Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AAAS ENSG00000094914 "Aladin WD repeat nucleoporin" Q9NRG9 12 53307456-53324864 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040086 Approved Approved "Nuclear membrane,Centrosome,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Centrosome, Cytosol" "HPA040086: AB_10805602" "unprognostic (1.53e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-3)" "unprognostic (1.70e-1)" "unprognostic (4.34e-1)" "unprognostic (1.00e-2)" "unprognostic (1.57e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.95e-1)" "unprognostic (9.82e-2)" "unprognostic (2.53e-1)" "unprognostic (7.44e-2)" 17.0 36.3 12.3 13.8 15.0 19.1 17.1 15.2 15.6 20.3 15.1 19.1 12.3 19.1 7.2 19.3 19.9 9.4 22.7 12.9 13.7 21.7 24.6 14.0 17.6 14.3 14.1 19.2 23.9 18.0 24.8 17.4 14.8 18.4 15.1 12.3 18.5 11.7 22.6 17.3 17.7 16.8 13.7 22.2 21.6 27.3 14.0 25.2 19.4 18.5 21.6 17.8 17.9 17.2 26.1 77.3 63.2 38.0 28.6 32.2 38.9 29.8 31.3 72.6 42.1 54.0 56.7 62.2 47.4 37.3 41.9 37.6 106.4 78.8 42.1 41.0 68.1 49.7 29.9 40.7 26.4 45.5 37.9 28.1 39.4 48.9 44.6 40.4 56.6 56.2 67.6 70.6 30.4 72.8 71.2 46.1 40.0 27.7 53.1 72.1 39.3 69.4 38.2 17.5 32.8 41.3 20.2 46.9 21.0 40.2 61.2 38.8 25.5 34.9 51.1 27.4 32.9 32.5 43.5 54.7 25.6 39.6 40.5 1.0 17.7 10.7 18.4 20.2 20.8 20.0 15.9 16.8 18.8 21.8 21.7 21.4 1.1 10.5 22.5 22.6 17.4 15.2 12.3 15.0 15.2 15.6 12.9 13.7 14.3 14.1 14.8 13.7 14.0 17.2 11.7 12.8 7.8 17.9 15.1 7.4 19.0 26.2 10.2 11.8 13.2 13.0 8.2 17.2 15.4 14.7 16.7 58.4 13.7 9.3 13.7 20.4 12.5 11.9 12.9 11.7 8.4 41.2 7.3 18.3 49.5 14.9 13.3 8.9 8.2 13.1 11.0 12.0 28.5 1.7 6.6 13.1 18.3 12.4 9.3 26.2 17.7 10.6 10.6 5.6 11.6 18.0 15.5 6.6 11.4 8.9 11.0 12.8 20.8 8.1 11.2 18.5 12.6 15.5 19.7 11.0 39.7 34.2 40.5 13.1 7.4 36.5 11.4 14.9 17.2 13.0 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 89.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 777.7;Rod photoreceptor cells: 640.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebral cortex: 31.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 9.1 12.6 0.3 8.1 0.6 12.0 8.1 0.9 31.0 7.1 0.0 7.0 4.6 9.9 9.9 7.4 7.5 5.4 20.4 2.9 0.0 10.5 5.1 10.3 9.0 4.7 2.9 5.5 13.1 89.7 13.7 9.9 3.5 8.6 6.3 28.2 6.7 8.2 13.0 6.3 8.5 7.6 0.0 8.6 12.6 6.7 4.8 13.2 23.4 6.7 7.7 7.8 7.1 4.8 25.1 15.3 14.6 12.3 13.7 14.3 41.0 19.4 16.8 12.0 11.3 15.6 10.0 0.9 4.6 27.6 16.5 11.4 11.7 11.4 27.1 20.6 4.4 13.3 9.0 10.0 11.7 9.5 31.3 12.9 9.6 23.7 30.9 10.2 27.4 12.3 3.2 14.1 22.5 3.7 8.8 5.6 6.4 4.9 8.3 5.8 13.8 2.2 10.0 51.0 4.2 6.6 12.0 8.8 10.2 9.9 5.3 12.9 25.6 26.4 17.5 19.7 19.4 12.9 3.9 1.5 23.0 16.0 19.1 1.4 0.5 0.2 1.4 0.2 1.4 0.1 1.3 1.0 0.3 0.3 1.7 1.5 1.5 1.1 2.2 0.2 1.0 0.5 0.3 0.6 0.9 31.0 2.9 0.0 4.7 2.9 3.5 0.0 4.8 4.8 54.6 35.3 34.2 77.7 13.4 15.9 20.8 15.9 32.5 254.4 42.2 40.9 86.7 102.9 19.3 143.5 777.7 81.6 149.1 130.6 43.0 46.0 23.9 36.6 67.4 56.0 72.1 35.3 265.8 67.4 56.3 29.5 44.9 65.7 21.0 24.4 118.2 38.2 62.4 306.2 327.7 31.6 12.2 128.8 23.5 32.7 38.2 67.1 10.6 156.4 72.7 53.2 252.4 147.8 113.9 55.9 76.3 46.6 57.4 42.1 56.0 90.0 10.7 640.8 19.7 26.7 45.5 46.9 59.3 23.3 9.9 213.3 158.1 33.6 21.7 49.0 AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Hepatocytes: 113.9;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 41.5;NTERA-2: 55.3;SuSa: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 19000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favorable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 9.7 5.9 10.0 1.8 12.2 0.2 8.4 10.3 14.4 8.2 15.5 5.2 0.9 9.5 7.5 3.2 11.7 2.1 9.2 9.4 10.6 13.9 44.3 6.3 1.4 11.6 11.0 25.2 4.8 7.1 3.5 3.2 11.4 5.4 1.4 3.7 3.5 4.8 8.6 2.8 3.6 4.4 10.1 2.9 5.5 2.2 11.0 1.5 4.7 6.2 1.4 6.9 6.2 11.8 0.1 0.0 21.9 41.5 27.3 13.5 9.4 5.4 8.0 7.3 9.1 12.6 0.1 0.0 0.2 6.6 8.3 4.1 33.5 16.8 9.6 0.0 12.2 9.4 4.3 12.5 22.0 0.0 2.9 12.2 0.5 9.2 7.1 18.9 19.8 12.1 2.7 15.5 5.1 0.1 0.9 0.0 55.3 0.1 1.7 11.8 16.3 0.3 5.3 2.4 2.7 0.7 1.5 0.0 5.3 37.8 0.5 0.0 8.1 13.6 3.4 7.0 8.3 3.5 3.0 0.0 4.9 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 12.2 10.3 14.4 9.4 10.6 11.6 11.0 11.4 10.1 11.0 11.8 16.0 9.6 37.8 145.9 2.1 6.2 9.0 2.8 14.8 7.0 8.7 6.3 9.7 14.3 5.6 14.7 16.7 11.6 1.5 0.6 0.0 2.7 12.2 4.1 24.0 11.7 3.0 5.2 5.0 1.8 3.3 14.4 5.6 7.7 3.8 18.1 24.7 113.9 1.5 11.8 4.4 2.6 2.0 2.2 2.5 7.4 19.0 1.4 12.4 35.6 0.0 8.9 0.0 106.1 132.5 2.3 2.5 24.5 1.6 4.7 5.4 8.6 0.9 3.3 19.7 38.9 15.8 12.4 2.4 7.8 4.7 5.1 2.1 8.0 1.9 4.8 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCA13 "FLJ33876, FLJ33951" ENSG00000179869 "ATP binding cassette subfamily A member 13" 7 48171458-48647497 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "bone marrow: 44.6" "Group enriched" "Detected in some" 5 "Basal respiratory cells: 33.8;Club cells: 25.8;Respiratory ciliated cells: 101.5" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.8;LHCN-M2: 2.4;U-2 OS: 6.4;U-266/84: 2.9" "Not detected" "Not detected" HPA063601 Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Centrosome, Cytosol" "HPA063601: AB_2685057" "unprognostic (8.97e-2)" "unprognostic (5.82e-2)" "unprognostic (3.18e-1)" "unprognostic (6.48e-2)" "unprognostic (2.65e-2)" "unprognostic (5.59e-2)" "unprognostic (5.19e-2)" "unprognostic (2.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.86e-3)" "unprognostic (6.03e-3)" "unprognostic (3.26e-1)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (3.62e-2)" 0.0 0.0 0.1 0.1 0.3 44.6 0.6 0.1 0.2 0.3 0.3 0.2 0.2 0.1 1.1 1.2 1.2 0.3 0.0 0.3 0.1 0.9 0.3 1.3 0.1 0.1 0.3 0.0 0.7 0.0 1.2 0.0 0.1 0.0 0.3 0.4 0.9 0.2 0.0 0.9 0.1 0.0 0.0 0.5 0.0 1.6 0.1 0.6 3.0 0.0 1.7 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.7 0.0 0.2 0.0 0.0 0.0 1.3 0.0 1.2 0.3 0.7 1.4 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.0 0.2 0.0 0.1 2.4 0.0 0.0 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 6.4 0.3 1.0 1.9 2.9 0.0 0.8 0.3 0.2 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.2 0.3 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.1 33.8 0.0 0.0 1.2 0.3 10.5 0.0 25.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 10.2 1.8 0.5 0.2 0.0 0.8 0.6 0.4 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.9 0.2 0.0 0.5 0.2 6.1 0.0 0.0 6.1 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 101.5 0.0 0.0 0.1 1.8 3.6 3.7 1.7 0.0 0.0 0.1 0.1 0.5 0.2 ABCA7 ABCX ENSG00000064687 "ATP binding cassette subfamily A member 7" Q8IZY2 19 1039997-1065572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Phagocytosis, Transport" Translocase "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;pituitary gland: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Bipolar cells: 70.6;Cone photoreceptor cells: 175.2;Extravillous trophoblasts: 303.3;Rod photoreceptor cells: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 20.4;HMC-1: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA041564 Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Plasma membrane" "Cell Junctions" "HPA041564: AB_2677550" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (7.26e-4)" "prognostic favorable (1.12e-4)" "unprognostic (8.88e-2)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (1.51e-3)" "unprognostic (3.68e-2)" "unprognostic (8.99e-3)" "unprognostic (2.08e-2)" "unprognostic (3.66e-1)" "unprognostic (7.88e-2)" "unprognostic (7.85e-2)" 4.4 3.0 3.4 5.5 3.9 27.4 3.3 4.0 6.1 3.2 11.5 3.8 2.3 1.2 0.2 7.6 2.1 2.1 3.1 3.6 3.7 6.4 4.2 9.5 8.5 5.8 4.5 0.5 7.7 2.7 28.7 1.2 5.3 5.3 1.2 25.5 8.6 1.1 3.8 5.9 10.1 0.5 3.0 26.6 3.8 1.7 4.1 10.0 5.7 0.3 3.2 2.3 2.8 3.2 4.7 6.4 0.5 4.4 7.2 2.2 7.3 0.8 1.0 0.4 0.6 5.2 2.8 13.9 5.6 1.3 0.6 8.0 1.3 6.2 0.4 10.2 2.5 6.7 20.4 5.6 1.8 3.9 40.3 3.8 1.8 0.9 1.2 4.4 1.4 7.7 10.2 6.9 1.3 2.2 4.3 2.2 0.9 3.3 2.5 3.1 0.8 11.6 3.8 6.0 0.3 1.3 8.2 1.9 1.2 1.1 4.6 7.1 2.2 0.4 1.6 3.7 0.8 9.9 6.6 5.7 2.1 7.4 2.0 2.8 1.4 5.9 1.8 1.2 1.1 0.6 0.9 1.2 2.1 0.9 0.8 1.5 3.3 1.1 1.3 7.3 0.4 1.3 3.4 3.9 4.0 6.1 3.6 3.7 5.8 4.5 5.3 3.0 4.1 3.2 4.1 73.7 21.9 8.5 13.2 3.3 0.8 10.7 5.2 70.6 4.8 2.2 6.0 4.3 14.0 5.5 175.2 4.6 9.1 14.7 1.9 2.7 7.3 8.9 1.4 2.9 3.5 13.3 12.9 2.5 303.3 1.5 5.6 6.9 10.1 2.0 2.5 4.9 7.9 15.2 11.5 4.7 16.2 12.6 7.5 4.8 0.0 12.7 0.0 4.7 19.6 13.1 9.2 1.5 2.4 7.0 9.6 0.0 12.0 1.5 1.7 1.3 17.5 149.1 0.0 2.7 2.7 0.7 2.0 6.6 3.4 25.7 12.6 1.0 5.3 1.9 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 101.7;intestine: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.8;Distal enterocytes: 109.9;Microglial cells: 570.6;Paneth cells: 106.2;Proximal enterocytes: 204.6" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cell line enhanced" "Detected in some" "CACO-2: 67.3;HEK 293: 20.4;HEL: 37.7;Hep G2: 18.5;RPTEC TERT1: 24.2;SH-SY5Y: 78.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 12.2" "CAB001716, HPA002199, HPA074614" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Plasma membrane" "Focal adhesion sites" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 101.7 14.1 3.9 13.6 1.9 3.6 13.7 17.6 6.4 5.3 16.6 26.4 11.0 3.6 3.1 5.0 15.5 1.9 15.3 15.6 33.7 28.0 6.4 3.2 17.6 14.4 2.2 2.0 1.4 0.5 2.3 19.7 4.2 18.2 2.2 1.2 3.1 0.2 1.5 70.7 9.8 15.1 4.2 2.1 0.9 19.3 2.7 1.9 1.4 3.5 3.6 1.7 14.3 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 20.4 37.7 4.2 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 24.2 0.2 0.9 78.9 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 4.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 11.1 0.0 27.2 0.8 2.7 6.8 0.0 2.5 1.7 6.6 0.2 17.9 0.0 0.1 0.0 2.5 14.1 13.6 13.7 17.6 15.3 15.6 17.6 14.4 19.7 15.1 19.3 14.3 17.1 0.0 3.0 3.9 9.9 0.8 0.1 0.0 1.2 1.9 0.4 3.9 3.0 95.8 0.6 49.7 0.0 5.8 24.7 109.9 5.9 13.8 27.3 0.6 0.6 52.9 0.0 7.8 16.1 1.9 0.2 3.7 0.0 0.7 3.8 0.3 2.5 38.4 0.4 0.0 11.4 15.8 0.0 0.6 1.2 3.8 0.9 1.6 0.0 570.6 0.2 0.2 32.0 6.0 3.2 8.1 106.2 0.0 4.6 0.2 204.6 57.7 0.7 1.1 0.0 0.4 1.3 0.4 0.9 0.2 0.6 9.9 24.5 0.1 19.9 0.3 ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.6;RT4: 1.6;TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" 1.5 0.0 0.3 0.1 0.3 0.0 0.6 0.3 0.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 80.8 0.0 0.1 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.0 6.2 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.4 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.2 0.2 1.0 0.6 0.5 0.3 0.2 0.3 0.0 41.7 44.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 19.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 16.5 0.1 0.0 1.8 0.0 2.7 0.8 0.0 0.0 6.6 0.0 0.0 24.0 0.0 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 9.1 0.0 3.8 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.6 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 41.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 51.3;granulocytes: 53.9;Microglial cells: 203.3" "Cancer enriched" "Detected in all" 8 "prostate cancer: 90.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 245.7;HMC-1: 256.3;RPTEC TERT1: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoli, Golgi apparatus" "HPA002476: AB_1844434" "unprognostic (8.77e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.55e-2)" "prognostic favorable (2.25e-10)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (5.55e-2)" "unprognostic (2.35e-2)" 2.2 1.3 2.5 6.1 2.3 4.1 6.9 2.5 2.5 4.9 7.2 9.2 4.9 3.4 18.8 2.0 10.2 6.1 2.0 2.3 5.4 18.0 1.3 7.6 3.9 4.3 3.7 3.7 3.3 22.5 1.4 2.1 4.6 41.1 8.5 0.9 1.5 5.5 5.3 2.9 5.4 6.3 4.9 4.1 5.2 4.7 3.2 3.9 7.7 1.7 6.3 15.4 1.8 5.1 18.5 31.7 5.3 9.4 9.5 12.3 1.3 14.4 14.3 12.6 10.9 43.8 13.2 10.2 9.3 19.5 9.0 24.0 7.9 7.1 15.8 30.7 12.1 245.7 8.8 8.8 19.2 28.6 256.3 9.4 3.2 9.1 18.5 17.9 16.4 11.3 25.8 0.4 17.1 5.9 5.4 4.6 6.2 22.3 7.9 7.7 14.3 26.9 69.3 40.4 12.5 9.3 4.8 1.2 10.1 5.9 0.0 15.1 27.0 13.3 8.6 11.2 17.3 0.1 0.0 4.0 25.4 16.0 6.6 0.2 0.5 0.2 1.3 0.6 1.1 1.4 1.0 1.5 1.8 1.6 0.6 1.5 0.3 1.9 2.3 0.3 1.5 1.3 2.5 2.3 2.5 2.5 2.3 5.4 4.3 3.7 4.6 4.9 3.2 5.1 4.6 9.6 32.7 28.4 5.8 4.2 7.0 7.3 4.0 0.1 0.6 0.6 4.5 8.6 9.1 23.9 22.9 0.1 2.0 2.7 0.0 6.9 3.8 4.2 11.3 19.8 0.0 51.3 13.6 3.1 0.4 5.7 6.1 6.0 53.9 9.5 2.9 0.6 4.5 0.0 10.3 4.0 0.0 2.5 8.1 2.0 6.8 10.7 1.8 203.3 13.5 0.5 4.1 16.1 2.5 2.9 8.3 1.9 8.3 27.1 0.5 26.4 4.7 0.8 0.0 8.2 3.1 0.9 8.3 3.4 7.5 0.3 6.4 17.3 9.2 4.5 ABCC5 "EST277145, MOAT-C, MRP5, SMRP" ENSG00000114770 "ATP binding cassette subfamily C member 5" O15440 3 183919934-184017939 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 167.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 196.0;Inhibitory neurons: 122.8;Rod photoreceptor cells: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044067, HPA052295" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA044067: AB_2678797, HPA052295: AB_2681789" "unprognostic (9.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.83e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (4.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.02e-1)" "unprognostic (5.91e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (1.10e-1)" "unprognostic (9.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-2)" 15.4 23.2 42.5 16.3 44.2 22.4 13.1 48.4 50.0 30.9 167.1 24.4 10.8 21.6 10.4 44.5 16.1 17.9 47.2 45.5 43.6 41.6 7.9 15.6 13.1 44.0 39.5 23.4 13.0 24.0 41.7 17.2 44.7 27.8 22.1 126.2 18.4 13.7 117.5 24.1 23.2 16.1 34.0 37.1 82.3 16.5 46.3 15.3 13.8 40.3 11.8 34.8 35.2 43.2 21.5 11.5 25.9 30.8 25.7 28.3 40.0 16.8 13.3 14.8 16.2 17.9 15.8 22.5 38.6 16.2 22.6 83.3 32.1 18.6 19.3 24.4 31.1 48.1 32.5 18.0 10.3 14.8 36.5 45.6 18.3 15.9 10.6 30.3 17.8 65.6 45.6 30.8 25.7 56.7 40.7 17.1 26.7 38.4 21.7 28.1 8.7 13.4 54.4 136.4 46.6 27.8 17.1 93.5 29.3 33.3 56.6 4.9 20.4 17.4 16.6 22.3 23.8 11.7 24.3 21.1 12.5 29.2 17.9 11.7 4.6 8.3 6.9 2.2 4.4 3.1 3.8 3.1 3.6 4.5 4.3 6.0 16.4 5.6 4.2 1.3 5.7 4.5 42.5 44.2 48.4 50.0 45.5 43.6 44.0 39.5 44.7 34.0 46.3 43.2 8.3 9.6 5.3 39.2 6.4 8.9 14.4 18.3 35.3 39.1 10.5 11.3 37.2 2.8 37.2 44.1 196.0 3.2 7.7 23.3 7.9 5.7 6.0 10.4 18.0 9.5 59.3 21.2 101.3 4.5 5.0 12.5 91.3 20.8 5.1 31.0 6.8 3.3 49.7 33.7 122.8 6.4 20.3 32.7 6.5 3.5 8.1 29.3 12.4 32.8 8.3 13.8 9.2 82.4 62.7 7.9 20.2 7.9 7.5 9.3 5.1 4.8 44.9 121.1 0.0 27.4 15.4 6.8 18.8 41.3 12.1 4.5 8.6 14.9 7.5 61.5 ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476879 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pancreas: 20.1;pituitary gland: 34.4" "Group enriched" "Detected in some" 4 "Astrocytes: 19.6;Bipolar cells: 39.0;Endometrial stromal cells: 17.9;Enteroendocrine cells: 22.0;Excitatory neurons: 48.2;Inhibitory neurons: 39.3;Oligodendrocyte precursor cells: 39.2" "Cancer enriched" "Detected in some" 9 "pancreatic cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 1.8;AN3-CA: 1.4;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" No NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoli "Golgi apparatus, Cytosol" "CAB011451: , HPA042318: AB_2677947" "unprognostic (4.30e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (4.73e-2)" "unprognostic (9.48e-3)" "unprognostic (2.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.53e-3)" "unprognostic (6.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (2.22e-2)" "unprognostic (1.96e-2)" "unprognostic (6.88e-5)" "unprognostic (2.72e-2)" "unprognostic (1.85e-1)" 0.4 2.8 2.6 0.0 3.7 0.0 1.8 3.9 5.2 3.5 0.0 0.7 0.5 2.6 1.4 0.1 0.6 0.0 1.6 3.1 1.4 0.5 0.1 5.0 0.0 3.3 2.7 0.4 20.1 0.2 34.4 0.4 3.3 2.1 0.3 2.2 0.0 1.5 1.5 0.2 1.0 0.2 0.6 0.1 6.1 0.4 1.2 0.0 3.4 0.6 0.0 0.4 1.3 3.5 0.0 1.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.7 3.9 5.2 3.1 1.4 3.3 2.7 3.3 0.6 1.2 3.5 0.3 0.0 0.0 19.6 0.3 0.0 0.1 0.0 0.0 39.0 5.3 3.7 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.5 17.9 0.3 22.0 0.0 48.2 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 39.3 0.7 0.0 0.3 0.5 0.0 0.0 0.1 0.0 3.7 0.0 1.9 0.0 39.2 7.6 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.0 0.7 2.0 0.1 0.8 0.0 0.1 0.0 0.1 2.6 0.1 0.2 ABHD14B "CIB, MGC15429" ENSG00000114779 "Abhydrolase domain containing 14B" Q96IU4 3 51968510-51983409 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 313.2;Proximal tubular cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 190.8" "Low region specificity" "Detected in all" "HPA036444, HPA036642" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA 2100000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli "Nucleoplasm, Cytosol" "HPA036444: AB_10672221, HPA036642: AB_10672225" "unprognostic (8.97e-2)" "prognostic favorable (6.92e-5)" "unprognostic (1.84e-1)" "prognostic favorable (5.42e-5)" "unprognostic (1.07e-1)" "unprognostic (2.21e-2)" "unprognostic (2.06e-3)" "unprognostic (1.35e-3)" "unprognostic (3.95e-1)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.93e-5)" "unprognostic (1.16e-1)" "unprognostic (3.55e-1)" "unprognostic (9.70e-2)" "unprognostic (3.70e-2)" 69.2 81.9 21.3 26.1 22.3 37.4 66.0 21.4 25.3 49.7 29.9 60.0 81.5 39.3 44.7 46.1 58.3 35.2 31.0 20.2 21.4 97.3 155.6 37.8 48.3 22.2 22.2 51.2 65.2 51.3 36.5 15.4 22.7 48.5 55.3 40.4 64.8 36.6 25.1 42.7 74.8 26.9 22.4 47.1 51.0 9.6 22.9 39.0 57.1 22.6 43.1 47.9 42.9 22.3 37.6 32.9 2.7 37.3 100.6 91.3 9.2 14.5 18.4 27.2 32.5 25.3 72.6 41.7 11.4 54.2 12.6 18.5 23.5 22.2 21.0 57.6 27.2 66.6 30.6 106.6 55.3 37.8 64.9 115.1 74.4 27.8 36.9 41.9 34.0 64.2 39.1 66.8 55.8 40.5 16.8 29.9 3.5 43.6 88.5 42.1 5.2 190.8 51.8 16.7 15.2 16.6 37.3 68.0 121.8 5.7 97.7 25.8 31.5 13.8 64.8 32.3 8.7 82.1 41.6 17.4 30.4 118.9 24.8 41.7 24.3 10.9 42.2 19.9 63.3 58.3 53.0 52.0 38.1 42.9 52.4 49.2 1.9 24.5 12.9 28.4 42.4 37.5 21.3 22.3 21.4 25.3 20.2 21.4 22.2 22.2 22.7 22.4 22.9 22.3 40.4 6.4 26.2 7.8 69.4 30.2 62.4 68.5 38.1 12.7 88.1 81.0 4.7 72.9 28.7 69.9 14.6 16.7 50.7 79.6 146.8 34.8 1.4 19.6 22.4 36.8 75.9 41.2 10.1 46.8 19.0 43.4 35.2 20.9 50.8 14.8 39.7 122.1 55.4 8.4 10.8 97.1 42.7 60.7 36.3 2.4 65.0 39.0 55.2 14.0 37.7 14.8 50.4 4.5 9.4 30.0 74.5 46.6 37.4 39.6 313.2 265.3 25.2 39.9 39.5 34.7 35.6 0.4 3.9 57.1 30.4 11.8 63.9 47.7 127.9 64.4 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.7;Paneth cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 209.6;RPMI-8226: 233.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 17.1 7.3 13.3 25.2 13.8 17.6 15.7 16.8 21.9 12.6 23.2 63.5 44.1 8.1 9.1 18.1 12.0 20.8 7.5 13.2 14.0 14.5 39.3 15.7 29.8 14.2 15.6 12.5 12.3 16.0 11.4 19.8 16.2 11.1 65.7 5.8 14.5 6.2 14.4 6.3 56.3 9.7 13.2 24.0 35.6 6.3 16.2 21.4 22.9 7.9 25.8 15.3 12.8 15.9 29.0 20.6 19.8 12.7 12.3 8.2 0.1 18.6 7.6 13.1 17.6 21.6 29.1 82.3 33.2 6.2 58.6 93.6 32.5 15.3 18.1 52.1 21.9 9.0 35.7 37.5 18.7 39.6 28.9 7.3 17.7 19.2 8.8 6.5 8.7 28.0 23.4 47.9 11.6 11.7 38.5 43.6 9.7 92.1 47.8 209.6 15.0 233.5 36.4 27.6 16.6 7.5 42.5 37.6 11.2 21.3 11.7 68.9 6.9 12.7 18.2 22.6 29.3 53.1 37.5 84.9 16.1 50.9 29.4 89.3 24.7 29.3 25.3 44.4 19.8 16.2 22.7 24.8 15.2 12.6 18.2 23.2 81.6 18.6 61.8 10.2 44.9 24.3 13.3 13.8 16.8 21.9 13.2 14.0 14.2 15.6 16.2 13.2 16.2 15.9 8.4 9.6 9.3 42.4 22.8 33.4 40.8 21.6 18.2 14.3 12.9 6.2 4.6 40.0 25.4 3.7 47.9 30.6 24.4 187.7 1.9 52.9 4.1 32.6 9.9 9.5 36.4 10.3 27.2 27.5 22.7 10.6 32.1 49.4 11.4 1.2 10.4 31.6 68.5 0.0 30.9 57.9 52.9 31.9 47.2 1.5 7.5 26.4 32.0 33.7 29.6 7.8 26.8 17.1 10.7 51.1 126.6 6.4 45.5 32.0 93.8 8.8 40.8 15.7 13.1 6.8 13.2 4.1 9.7 22.4 15.2 94.3 38.3 5.4 36.8 36.8 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 38.8 12.5 6.7 8.5 8.6 39.6 27.9 10.5 8.9 9.8 6.0 12.3 9.9 5.7 4.1 31.1 5.1 11.6 13.4 6.8 7.4 12.0 21.7 16.4 3.4 9.2 8.2 4.6 16.0 12.2 5.6 10.2 9.1 7.1 7.5 6.3 27.4 8.4 15.0 38.0 10.5 9.3 9.3 9.4 12.1 10.8 8.4 6.8 15.5 18.5 7.9 16.7 16.9 11.9 18.9 6.8 8.2 9.7 32.0 12.8 17.1 77.4 27.1 18.8 14.9 9.4 6.4 16.2 10.9 23.2 15.8 5.8 16.5 18.5 22.6 58.4 13.2 36.6 24.4 7.5 15.7 9.2 13.2 13.0 64.6 31.3 28.5 18.8 33.3 10.8 23.9 14.2 46.9 11.0 7.6 6.9 22.8 16.7 20.4 3.1 24.1 8.6 27.9 40.4 10.6 13.6 36.9 20.5 9.8 9.8 18.9 8.9 19.3 18.1 13.6 35.0 34.5 11.1 34.0 7.7 20.3 17.3 16.0 67.8 14.7 9.5 2.3 7.9 1.7 3.5 1.7 2.7 6.8 4.0 1.6 2.5 42.5 2.0 5.7 1.9 4.8 5.3 6.7 8.6 10.5 8.9 6.8 7.4 9.2 8.2 9.1 9.3 8.4 11.9 117.5 25.6 51.8 12.7 44.8 39.9 27.5 25.9 88.8 11.9 149.9 116.2 10.3 14.3 49.6 27.6 27.1 16.7 80.3 65.0 33.2 57.5 19.5 47.5 49.0 34.6 36.2 69.0 24.1 61.5 24.9 53.7 67.8 114.0 16.5 8.8 18.2 12.7 18.0 3.3 24.1 23.7 34.6 44.1 17.4 17.1 5.3 79.8 7.2 11.2 35.9 11.0 12.3 18.1 28.8 75.2 49.8 5.7 41.8 25.5 98.5 39.8 19.1 17.4 0.0 32.0 46.4 47.3 41.9 111.7 40.9 205.4 42.6 15.2 21.9 71.6 ABI2 "ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2" ENSG00000138443 "Abl interactor 2" Q9NYB9 2 203328280-203447728 "Predicted intracellular proteins" "Host-virus interaction, Neurogenesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070567 Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA070567: AB_2686281" "unprognostic (5.26e-3)" "unprognostic (5.26e-3)" "unprognostic (1.86e-1)" "unprognostic (4.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (1.81e-3)" "unprognostic (7.05e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-3)" "unprognostic (6.19e-3)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.24e-2)" "unprognostic (2.94e-1)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" 10.5 13.2 31.0 9.5 41.9 3.3 15.2 22.9 38.4 19.0 10.0 18.7 5.7 28.0 18.7 11.9 22.5 13.4 32.7 40.4 33.0 20.9 7.4 16.1 8.2 16.3 24.1 27.9 7.5 20.4 20.5 19.4 17.3 18.7 10.7 30.0 8.6 23.0 7.4 7.6 8.9 25.2 21.3 12.9 9.3 27.5 36.0 22.2 26.5 15.8 8.7 14.6 11.9 22.5 19.3 29.4 102.5 64.4 23.9 40.5 22.6 33.0 29.0 27.9 32.2 27.3 35.5 0.0 22.0 39.0 38.8 20.9 47.1 34.6 54.8 9.5 27.4 47.9 30.9 21.4 36.3 20.6 21.1 28.8 16.5 51.2 39.5 80.5 52.6 54.1 34.7 41.8 49.7 35.0 52.8 20.4 53.5 18.2 64.8 34.5 51.4 3.5 29.3 19.6 43.2 55.3 6.2 19.2 37.4 76.8 25.0 23.9 39.9 50.4 43.0 27.8 36.2 29.3 28.7 26.6 54.7 8.5 33.2 0.2 1.4 0.0 3.3 1.6 3.6 1.4 3.7 3.7 4.0 1.3 4.4 3.9 0.2 3.9 3.8 12.7 4.4 3.2 31.0 41.9 22.9 38.4 40.4 33.0 16.3 24.1 17.3 21.3 36.0 22.5 39.7 54.5 26.5 123.4 14.7 30.1 55.7 37.7 34.1 111.9 39.5 38.7 56.7 28.6 32.8 53.3 162.6 23.7 33.1 10.1 33.2 24.3 128.2 62.3 68.4 43.6 49.2 30.3 201.3 13.1 15.7 54.1 25.0 72.3 15.8 100.0 65.7 12.3 16.7 102.6 128.6 10.9 20.3 11.4 62.3 81.6 46.6 22.1 49.8 57.1 18.6 67.6 26.8 114.1 94.2 15.5 19.4 63.2 18.3 44.2 11.1 38.5 83.1 89.6 26.3 70.5 67.9 89.0 52.4 22.0 26.1 19.7 21.7 69.9 17.0 37.5 ABITRAM "C9orf6, CG-8, FAM206A, FLJ20457, Simiate" ENSG00000119328 "Actin binding transcription modulator" Q9NX38 9 108934400-108950744 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.7;Cytotrophoblasts: 6.0;Extravillous trophoblasts: 10.6;Fibroblasts: 4.3;Hofbauer cells: 7.8;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035917, HPA035918" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA035917: AB_2674860, HPA035918: AB_10670593" "unprognostic (4.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.85e-1)" "unprognostic (4.00e-3)" "unprognostic (1.05e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.16e-2)" "unprognostic (3.50e-2)" "unprognostic (1.57e-2)" "unprognostic (3.25e-2)" "unprognostic (2.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" 14.2 11.9 17.2 10.0 18.7 15.6 17.2 16.8 21.9 12.5 18.7 14.9 14.4 13.6 25.1 16.4 21.5 10.9 15.8 17.7 17.3 13.6 14.6 12.7 9.0 16.8 17.1 13.5 13.3 23.2 13.9 12.5 17.2 12.1 16.2 24.7 15.3 14.2 13.2 24.5 13.1 12.5 17.5 8.5 14.5 20.2 17.5 11.9 19.0 11.8 12.0 11.9 11.4 18.3 18.5 19.8 19.5 23.4 36.2 44.6 28.1 17.1 20.0 17.0 13.9 29.5 9.7 17.0 9.8 16.6 22.3 41.3 17.2 18.3 16.0 10.4 17.6 10.5 25.8 27.0 30.7 40.4 13.3 25.3 33.6 20.7 47.6 20.9 23.7 26.1 39.7 16.6 20.3 53.0 28.9 16.3 22.6 55.9 28.7 13.9 33.9 18.9 22.5 19.2 26.7 13.7 27.0 23.3 30.1 20.0 31.6 21.4 14.9 9.2 16.9 39.3 21.7 14.7 38.5 12.6 30.1 15.6 13.4 38.8 31.2 31.0 14.8 33.4 22.6 16.5 23.1 19.6 35.5 10.8 22.9 17.6 37.4 21.1 34.6 37.0 21.1 20.1 17.2 18.7 16.8 21.9 17.7 17.3 16.8 17.1 17.2 17.5 17.5 18.3 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 6.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 10.6 4.3 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 7.3 0.3 0.0 0.0 0.0 ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 197.6;Cardiomyocytes: 61.7;Hepatocytes: 116.0;Oligodendrocyte precursor cells: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 75.3;HHSteC: 77.6;HSkMC: 89.4;hTERT-HME1: 90.9;hTERT-RPE1: 76.2;TIME: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" 68.4 7.4 19.2 3.8 18.0 0.5 57.6 49.7 19.1 12.5 6.8 11.1 2.7 10.4 6.3 33.2 14.4 7.1 87.8 20.4 26.7 19.8 115.8 20.0 5.3 37.2 25.2 3.9 2.7 59.6 6.8 34.4 28.7 9.1 5.0 28.6 6.5 8.2 45.8 8.3 7.8 10.6 34.0 8.7 5.4 2.0 29.9 2.2 9.2 38.7 4.5 14.1 17.7 30.2 23.6 4.8 0.0 0.2 39.6 75.3 0.1 16.1 44.8 9.1 15.8 0.1 16.2 0.0 2.7 20.5 47.9 0.5 0.1 18.9 17.7 0.1 0.2 0.0 1.4 0.6 77.6 0.0 0.1 89.4 5.1 32.5 90.9 76.2 41.1 0.0 0.0 7.2 54.8 9.2 0.0 0.0 0.2 1.5 63.0 0.0 0.1 0.0 50.3 16.0 6.3 0.1 3.3 1.1 8.7 1.2 1.5 0.1 103.9 18.9 4.2 19.9 27.7 0.1 0.0 0.0 33.5 0.0 55.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 2.7 19.2 18.0 49.7 19.1 20.4 26.7 37.2 25.2 28.7 34.0 29.9 30.2 197.6 0.0 3.7 21.5 1.3 1.5 1.2 2.6 0.6 2.5 7.6 3.9 61.7 18.6 5.3 0.0 0.0 0.2 0.3 0.0 5.9 8.7 3.0 0.5 2.5 39.6 0.0 0.0 31.0 3.5 0.7 9.4 3.6 2.5 1.3 0.0 34.2 116.0 12.3 28.6 33.7 0.0 8.2 13.5 1.1 0.5 0.3 8.5 5.4 21.5 0.9 19.3 0.0 63.8 25.6 22.5 0.0 0.7 0.1 2.5 0.0 23.5 4.9 25.1 0.0 7.4 7.7 1.7 2.7 2.0 1.6 0.4 0.7 0.5 0.0 22.2 AC005726.1 ENSG00000258472 "Novel protein" 17 28455752-28614185 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 13.2;Club cells: 5.6;granulocytes: 6.3;Proximal tubular cells: 20.4;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.26e-2)" "unprognostic (1.82e-1)" "unprognostic (6.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (7.25e-2)" "unprognostic (5.96e-2)" "unprognostic (4.58e-2)" "unprognostic (9.22e-3)" "unprognostic (3.17e-3)" "unprognostic (1.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 9.6 13.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.4 0.0 0.0 5.6 3.7 0.0 1.7 0.5 0.0 1.9 1.2 0.0 1.7 2.4 1.4 0.0 0.0 0.0 2.0 0.8 1.6 0.0 3.2 6.3 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 20.4 5.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.3 1.1 1.2 0.0 0.0 AC006059.2 ENSG00000280571 "Novel protein" 3 42705756-42804518 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 2.2;retina: 7.6" "Cell type enriched" "Detected in single" 4 "Alveolar cells type 1: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047429 Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 11: Alveolar cells - Smell perception" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA047429: AB_2680043" "unprognostic (1.72e-1)" "unprognostic (4.20e-1)" "unprognostic (8.65e-2)" "unprognostic (2.65e-1)" "unprognostic (7.02e-2)" "unprognostic (8.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (4.32e-2)" "unprognostic (5.96e-2)" "unprognostic (6.09e-3)" "unprognostic (2.99e-2)" "unprognostic (3.01e-2)" 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.7 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.1 0.0 0.0 0.7 0.0 0.0 7.6 0.1 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.2 0.6 0.4 0.7 0.7 0.6 0.7 0.7 0.5 2.2 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC007325.2 ENSG00000277196 "Proline dehydrogenase 1, mitochondrial" Unmapped 138082-161852 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "brain: 113.8;choroid plexus: 218.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.9;Distal tubular cells: 7.9;Endometrial ciliated cells: 2.5;Proximal enterocytes: 5.6;Squamous epithelial cells: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "OE19: 345.1;RPTEC TERT1: 183.1" HPA020361 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" 2.2 0.6 83.9 0.8 83.5 0.7 3.3 75.2 113.8 1.0 218.6 1.1 28.9 0.5 0.1 6.8 1.4 0.4 9.5 90.0 76.6 12.3 6.0 18.8 1.0 87.3 82.6 0.0 0.1 0.1 0.9 72.0 0.9 1.4 1.9 0.7 2.4 10.2 32.6 33.2 0.2 74.5 0.7 0.8 1.9 85.0 5.6 4.5 24.0 6.4 1.9 72.3 0.0 8.3 0.3 2.5 5.0 0.0 1.6 0.0 0.0 0.0 0.0 5.3 1.8 0.0 0.5 0.0 0.2 10.0 18.8 0.5 0.0 0.0 0.7 0.0 0.2 0.9 3.6 0.0 0.1 0.4 18.5 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.5 0.2 0.0 17.5 345.1 0.0 0.1 0.1 0.0 183.1 0.7 0.4 0.5 0.0 6.9 1.5 18.8 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.9 83.5 75.2 113.8 90.0 76.6 87.3 82.6 72.0 74.5 85.0 72.3 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.2 0.1 AC008397.2 ENSG00000285188 "Novel protein" 19 18207961-18255419 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "stomach 1: 3.6" "Cell type enhanced" "Detected in some" "Adipocytes: 2.0;Alveolar cells type 1: 9.6;Alveolar cells type 2: 10.6;Breast glandular cells: 2.2;Breast myoepithelial cells: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.2" "HPA048975, HPA054218" Uncertain Approved "Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 11: Alveolar cells - Smell perception" "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " 0.1 0.0 1.8 0.1 2.3 0.0 0.0 1.2 2.3 0.3 1.2 1.2 0.8 0.7 1.9 0.1 0.7 0.3 0.5 2.1 1.5 0.4 0.0 1.2 0.0 1.3 1.5 0.2 0.4 0.0 0.6 1.4 0.2 1.0 0.0 0.0 0.7 2.4 0.0 0.5 0.5 1.3 0.4 3.6 0.3 1.6 0.0 0.0 2.6 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.3 1.2 2.3 2.1 1.5 1.3 1.5 1.4 1.3 1.6 1.6 2.0 9.6 10.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 4.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 AC011455.2 ENSG00000269547 "Novel protein" 19 38915404-38949855 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.0" "HPA052730, HPA056957" Uncertain Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 6: T47d - Mammary gland" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (6.10e-2)" "unprognostic (3.79e-2)" 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012254.6 ENSG00000288607 "Elongin A3 family member B" Q3SY89 18 47022287-47023927 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 34 "brain: 3.4;choroid plexus: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048971, HPA049178, HPA050086, HPA053158" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 2.0 0.0 2.7 0.0 0.0 0.9 1.3 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 3.4 3.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.7 0.9 1.3 1.1 1.1 3.4 3.2 2.7 1.8 2.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012254.7 ENSG00000288631 "Elongin A3" Q8NG57 18 47028202-47029842 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 44 "brain: 3.9;choroid plexus: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048971, HPA049178, HPA050086, HPA053158" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 2.0 0.0 2.8 0.0 0.0 1.5 1.8 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.0 0.0 0.0 0.0 3.9 3.8 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.8 1.5 1.8 1.6 1.9 3.9 3.8 2.7 1.1 3.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC013489.1 ENSG00000173867 "Novel transcript" 15 88459501-88546585 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "granulocytes: 1.3;Respiratory ciliated cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: AB_2680541" "unprognostic (3.32e-2)" "unprognostic (9.46e-3)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" "unprognostic (2.84e-2)" "unprognostic (6.56e-3)" "unprognostic (4.03e-1)" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.02e-2)" "unprognostic (2.29e-2)" "unprognostic (1.10e-2)" "unprognostic (2.62e-3)" "unprognostic (1.79e-1)" "unprognostic (4.47e-1)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" 0.4 0.4 0.6 0.2 0.6 0.4 1.1 0.7 0.7 0.4 0.9 0.5 0.3 2.2 1.0 0.3 1.0 0.5 0.8 0.5 0.9 0.7 0.8 0.5 0.4 0.6 0.6 2.2 1.0 0.7 0.5 0.7 0.6 0.6 1.3 0.4 0.7 1.4 0.3 0.4 0.9 0.6 0.7 0.4 0.4 0.7 0.5 0.7 1.2 0.5 0.3 0.8 0.3 0.6 0.5 0.8 1.2 0.6 0.6 1.0 0.7 1.0 0.7 0.6 1.1 0.9 0.7 1.2 0.7 0.6 2.1 0.6 0.9 0.3 1.0 1.0 0.5 0.8 0.4 0.8 0.7 1.0 1.1 0.7 0.8 0.4 0.5 1.2 1.0 0.9 0.1 0.4 1.0 0.5 0.6 0.7 0.2 0.4 0.7 1.2 0.6 0.8 0.6 0.4 0.9 0.4 1.4 1.0 0.7 1.5 0.8 0.7 0.5 0.9 0.9 0.5 0.9 0.6 0.9 0.7 0.5 0.0 0.5 0.3 0.7 0.9 0.8 0.9 0.9 0.8 0.8 0.7 1.0 1.1 0.0 0.9 0.6 0.6 0.8 0.9 0.6 0.6 0.7 0.7 0.5 0.9 0.6 0.6 0.7 0.6 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC087721.2 ENSG00000285920 "Novel protein" 15 41284007-41380996 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4;Alveolar cells type 2: 5.3;Club cells: 5.6;granulocytes: 3.8;Respiratory ciliated cells: 2.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "HPA042904, HPA074847" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" 0.8 1.5 0.3 1.8 0.2 2.9 1.3 2.1 1.0 1.0 0.1 1.8 1.7 0.9 0.3 1.6 0.7 1.1 0.8 0.1 0.3 1.1 1.7 1.0 2.4 0.4 0.6 1.5 0.6 0.9 1.3 0.5 0.7 1.9 1.8 0.6 1.1 3.1 1.0 1.4 1.1 0.2 1.6 1.2 2.9 0.6 2.6 0.7 1.9 2.5 1.5 0.4 3.7 1.2 6.6 5.5 2.5 3.7 3.4 3.8 2.9 4.8 4.7 2.0 4.1 2.8 4.0 2.2 4.4 8.7 10.1 5.3 4.1 7.2 3.6 9.4 3.8 3.6 2.0 14.2 8.2 2.1 3.3 3.3 8.8 1.9 4.7 10.6 8.7 11.0 4.3 1.8 5.5 4.5 6.9 9.2 5.5 7.6 5.0 4.3 4.6 4.0 6.6 6.0 6.6 3.9 2.6 7.0 6.6 8.5 4.3 2.8 5.5 3.2 5.8 5.6 10.7 9.4 2.4 8.7 5.6 0.1 0.4 1.0 0.2 0.4 0.3 0.4 0.5 0.4 0.6 0.3 0.2 0.2 0.1 0.3 0.5 0.9 0.9 0.5 0.3 0.2 2.1 1.0 0.1 0.3 0.4 0.6 0.5 0.2 0.6 0.4 0.0 6.4 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 AC090373.2 ENSG00000288616 "Elongin A3 family member D" A6NLF2 18 46962768-46964408 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 37 "brain: 3.4;choroid plexus: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048971, HPA049178, HPA050086, HPA053158" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 1.4 0.0 2.2 0.0 0.0 1.2 1.4 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.0 0.0 3.4 1.9 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 1.2 1.4 1.0 0.9 3.4 1.9 2.4 0.8 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092143.1 ENSG00000198211 "Novel protein (MC1R-TUBB3 readthrough)" 16 89919165-89936092 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 6.6" "Cell type enriched" "Detected in single" 15 "Fibroblasts: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 10.7" "CAB011512, HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB011512: AB_444319, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.90e-4)" "unprognostic (6.87e-2)" 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC127029.3 ENSG00000285947 "Novel protein" 17 63917203-63931385 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 14.0;naive B-cell: 18.4" "Lineage enriched" "Detected in many" 5 "B-cells: 18.4" "Cell line enhanced" "Detected in single" "U-698: 2.2" "HPA009178, HPA043715" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA009178: AB_1078483, HPA043715: AB_2678632" 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.5 2.2 0.4 14.0 0.7 0.3 0.5 18.4 0.4 0.2 0.0 0.5 3.8 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC138696.1 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.7;MOLT-4: 1.2" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (2.24e-2)" "unprognostic (2.10e-1)" "unprognostic (3.56e-3)" "unprognostic (1.87e-1)" "unprognostic (8.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.20e-1)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (2.20e-2)" "unprognostic (3.99e-1)" "unprognostic (2.59e-2)" "unprognostic (4.06e-1)" 0.3 0.3 0.2 0.0 0.3 0.0 0.2 0.1 0.5 0.3 0.0 0.4 0.1 0.6 0.0 0.1 0.7 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.4 0.4 0.6 0.1 0.2 0.0 0.3 0.3 0.0 0.1 0.2 0.2 0.4 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.3 1.7 0.1 0.1 0.5 1.1 0.6 0.2 0.0 0.7 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 1.0 0.4 0.0 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.3 0.6 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.2 1.1 0.0 0.8 0.2 0.5 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.5 0.3 0.3 0.2 0.4 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC245033.1 ENSG00000260836 "Novel protein" 15 82536788-82573194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 32.1;Alveolar cells type 2: 45.1;Club cells: 8.6;granulocytes: 12.6;Respiratory ciliated cells: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-2197: 12.6" HPA055060 Uncertain Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "Nucleoli, Cytosol" "HPA055060: AB_2682686" "unprognostic (2.91e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.4 0.4 12.6 0.2 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.6 0.2 0.1 0.3 0.4 0.5 0.2 0.3 0.3 0.0 32.1 45.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 138.1;Excitatory neurons: 230.7;Inhibitory neurons: 197.8;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 16.2 25.4 10.8 3.7 10.8 4.9 22.2 9.0 15.8 11.5 11.3 14.4 5.2 12.1 13.8 25.2 10.8 4.8 7.7 9.5 11.2 13.6 23.3 13.3 2.0 11.1 9.9 11.3 10.5 10.9 19.2 3.8 11.1 26.2 6.4 8.0 14.6 9.6 15.1 15.4 9.6 8.0 8.6 7.3 12.6 16.4 10.3 3.7 8.9 3.6 5.5 19.9 14.6 12.3 34.7 7.0 39.8 42.6 54.7 53.2 13.9 15.2 21.3 15.9 27.5 27.4 5.9 5.0 12.0 24.3 39.4 33.9 7.5 51.1 23.7 13.6 23.2 27.3 15.5 28.0 9.2 14.8 5.3 43.4 29.0 40.2 30.0 18.8 27.5 25.1 66.5 3.2 2.1 27.3 16.3 22.8 30.4 21.5 22.1 24.1 25.3 6.4 36.1 38.5 45.0 17.0 27.8 12.3 12.7 34.8 24.9 16.8 23.8 12.7 20.6 17.3 3.9 8.7 11.5 42.0 11.7 12.3 17.2 0.5 0.8 0.1 0.6 1.3 0.6 0.7 0.7 0.7 1.0 1.1 1.1 0.8 0.3 0.6 0.8 0.7 1.0 0.6 10.8 10.8 9.0 15.8 9.5 11.2 11.1 9.9 11.1 8.6 10.3 12.3 6.8 32.1 51.7 138.1 8.0 11.6 20.8 14.8 22.2 17.2 17.3 11.7 8.0 2.8 16.5 11.0 27.1 16.0 7.0 5.3 9.8 6.7 66.3 19.1 15.6 8.3 9.0 10.7 230.7 8.3 7.6 10.4 15.8 15.9 7.0 19.5 6.4 17.3 5.8 23.5 197.8 7.3 14.2 3.8 4.3 51.2 9.9 6.1 10.6 58.1 4.3 18.2 4.1 181.0 186.9 7.2 6.4 15.8 9.3 22.8 4.8 7.0 10.5 11.8 6.6 10.0 7.8 20.8 20.5 27.8 15.9 16.3 6.4 43.2 10.0 22.0 ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225266 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 850.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria NA NA 98000 "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Nucleoplasm, Nucleoli" "HPA019006: AB_1844478, HPA020595: AB_1844479" "unprognostic (4.81e-2)" "unprognostic (2.86e-1)" "unprognostic (2.21e-2)" "unprognostic (1.09e-2)" "unprognostic (6.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (6.87e-4)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (2.84e-3)" 197.9 405.2 120.1 78.7 131.0 103.5 142.9 128.4 126.7 110.5 170.6 157.3 306.2 98.5 44.4 181.0 94.0 92.6 576.8 117.8 125.0 215.3 517.4 106.7 52.0 127.5 125.3 80.9 236.5 159.6 189.6 112.0 124.8 133.2 131.6 34.9 158.5 113.9 850.4 135.7 270.6 110.6 118.2 132.2 186.4 75.9 132.0 83.4 159.3 817.1 82.9 137.1 115.3 122.7 193.7 162.5 65.8 92.4 271.2 99.2 135.9 156.5 169.0 136.9 84.5 67.2 155.3 90.4 109.0 260.0 49.7 147.9 43.8 135.5 119.6 295.9 47.1 50.6 120.9 101.1 131.2 49.0 129.5 112.5 122.0 114.7 178.5 212.6 124.8 111.3 73.3 110.2 222.7 65.3 49.6 68.4 34.3 178.4 91.9 70.4 78.3 227.2 305.1 155.0 19.1 47.3 206.8 224.8 110.8 60.6 102.8 74.9 151.5 127.5 101.6 75.9 149.9 104.5 59.1 5.2 230.7 85.7 94.9 24.2 96.1 121.3 39.1 57.8 35.7 25.2 32.5 43.8 99.9 24.6 23.7 29.1 20.2 37.8 39.3 80.4 31.8 79.4 120.1 131.0 128.4 126.7 117.8 125.0 127.5 125.3 124.8 118.2 132.0 122.7 109.9 60.9 81.9 143.3 72.3 87.3 336.0 322.4 91.6 42.0 157.7 104.5 451.4 138.7 206.7 202.3 62.6 482.9 87.7 484.2 185.9 310.8 133.0 87.2 52.7 77.4 179.3 65.2 40.9 77.0 197.8 118.6 406.7 88.5 88.4 121.1 53.6 365.4 182.4 33.7 33.4 251.8 233.9 67.9 94.6 249.9 124.5 101.5 81.8 34.7 274.9 40.7 73.2 23.1 24.5 106.1 388.9 132.8 172.3 369.0 489.8 345.8 144.1 41.3 105.2 88.3 147.4 114.3 47.8 113.8 87.5 663.3 75.5 169.2 316.8 367.5 ACIN1 "ACINUS, fSAP152, KIAA0670" ENSG00000100813 "Apoptotic chromatin condensation inducer 1" Q9UKV3 14 23058564-23095614 "Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000657 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 30000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA000657: AB_1078091" "unprognostic (2.54e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.89e-3)" "prognostic unfavorable (4.88e-5)" "unprognostic (1.49e-3)" "unprognostic (9.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.00e-2)" "unprognostic (6.64e-3)" "unprognostic (1.35e-3)" "unprognostic (4.34e-2)" "unprognostic (2.78e-2)" "unprognostic (2.28e-2)" "unprognostic (7.33e-2)" 41.5 57.7 58.3 35.0 60.2 66.7 36.6 64.3 64.6 46.1 62.7 42.6 28.6 41.5 30.1 50.9 39.3 24.3 44.1 57.5 63.4 51.3 47.5 33.8 45.2 60.9 60.6 48.7 45.1 41.4 48.5 37.2 59.9 45.8 33.2 39.0 39.1 27.8 53.0 39.5 46.0 38.9 55.7 66.4 45.3 47.6 61.6 52.8 47.1 36.5 47.4 41.9 41.3 64.4 77.1 77.6 120.0 97.7 73.3 58.5 120.2 83.8 58.8 98.9 80.0 103.8 87.8 141.8 48.4 69.7 65.0 82.6 167.4 95.6 100.7 100.2 74.3 124.5 82.9 144.8 41.8 136.6 106.4 69.0 58.0 101.5 84.8 81.0 87.9 103.4 117.2 55.1 75.7 96.5 156.1 134.6 135.1 84.6 73.3 139.7 93.0 75.8 82.9 133.3 79.7 58.6 111.2 71.7 69.1 86.7 59.2 109.0 90.7 67.3 67.3 64.7 78.5 57.9 70.2 144.0 59.9 101.8 74.8 5.3 4.0 5.1 4.2 3.5 3.2 3.8 2.9 3.2 3.4 5.4 3.8 3.7 10.8 7.5 3.2 5.5 3.5 2.6 58.3 60.2 64.3 64.6 57.5 63.4 60.9 60.6 59.9 55.7 61.6 64.4 49.8 70.5 123.0 44.4 61.6 37.3 30.2 52.7 64.9 38.1 43.4 40.8 67.9 32.9 67.2 35.0 27.1 58.0 65.0 64.4 17.6 53.4 42.5 70.5 97.6 55.5 58.3 76.2 41.0 49.3 66.8 60.3 85.1 90.1 130.6 79.4 35.0 28.8 47.1 15.2 43.6 50.1 42.7 38.1 40.8 10.9 46.0 52.5 26.6 44.0 53.4 26.1 54.6 45.8 65.6 59.4 49.7 38.4 65.4 43.5 37.7 21.6 82.6 43.3 6.6 52.4 66.9 42.1 39.2 58.5 46.5 69.2 65.2 86.1 55.8 38.4 ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.4;placenta: 16.0" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.0;Extravillous trophoblasts: 106.2;Syncytiotrophoblasts: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.9;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.9;NK-cells: 1.1" "Cell line enhanced" "Detected in some" "BEWO: 51.2;HEL: 17.1;SK-BR-3: 28.0;U-937: 10.7" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" 6.7 1.0 1.5 1.0 1.0 0.7 2.8 1.5 1.3 1.7 0.9 1.9 0.9 0.9 2.8 1.6 2.3 1.3 1.3 1.0 0.5 1.5 9.4 1.6 1.1 1.4 1.4 0.4 0.9 0.4 0.5 16.0 1.3 0.6 2.1 0.7 2.2 0.4 0.6 2.6 1.1 1.1 0.6 0.7 1.1 0.8 1.1 0.4 2.9 0.9 2.1 1.8 2.3 1.3 0.1 0.0 0.2 0.4 2.4 0.2 51.2 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.1 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 17.1 0.4 3.1 0.1 0.2 1.9 0.5 0.5 0.0 0.1 0.0 0.1 0.5 2.2 0.4 0.3 0.3 0.0 0.2 0.1 0.7 0.2 0.1 0.0 0.1 0.7 7.5 0.3 0.1 1.3 28.0 0.1 2.9 2.8 0.3 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.1 0.1 10.7 0.1 0.4 0.1 3.9 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.1 0.4 1.1 0.3 0.1 0.0 0.1 1.5 1.0 1.5 1.3 1.0 0.5 1.4 1.4 1.3 0.6 1.1 1.3 1.0 0.0 0.0 9.8 0.1 0.1 0.1 0.3 0.0 0.7 1.2 0.3 0.8 1.5 3.3 0.0 2.1 33.0 0.3 3.0 1.9 0.1 3.0 3.7 0.8 3.3 1.8 0.0 2.0 0.0 106.2 2.1 0.0 5.9 2.5 2.5 4.6 7.0 5.3 1.7 1.2 0.6 0.0 0.6 0.4 1.8 0.3 0.4 0.0 5.6 0.1 2.6 0.0 1.0 4.5 0.8 0.5 1.2 0.1 0.4 1.6 0.5 3.4 1.0 0.0 0.4 0.3 4.8 5.4 0.0 0.0 73.6 0.5 0.5 1.1 0.6 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81329996-81394179 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 100.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 36.2" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037723 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA037723: AB_10672606" "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.5 2.7 100.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.5 0.3 0.5 0.3 0.3 0.6 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 8.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 36.2 0.5 0.0 1.2 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 3.4 4.2 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7600 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: AB_10696506" "unprognostic (5.69e-2)" "unprognostic (6.34e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (1.12e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (9.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (6.53e-2)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" 24.1 18.8 8.0 19.5 7.5 15.8 19.8 7.5 9.5 17.7 10.3 22.0 15.5 22.5 8.4 12.1 17.3 13.6 49.3 7.2 9.1 15.5 14.5 26.1 12.7 8.0 7.5 15.1 14.0 11.7 8.8 17.8 8.6 16.1 16.4 9.6 18.6 22.1 27.6 12.5 15.8 32.3 6.9 18.4 17.7 6.2 8.5 6.3 17.4 14.2 12.5 21.3 14.7 7.5 81.5 54.0 23.1 51.4 37.2 42.0 11.7 62.7 54.3 60.7 58.4 48.5 71.4 4.1 39.1 70.5 81.8 48.3 29.6 79.9 84.2 18.8 44.6 27.4 55.0 35.6 49.9 10.8 33.3 37.5 53.6 71.5 80.5 39.6 90.3 0.6 17.7 26.7 66.7 28.4 15.2 26.1 33.9 31.8 65.3 15.7 87.6 34.4 72.8 29.8 4.5 22.1 68.4 28.3 41.6 85.5 31.9 14.0 84.7 50.7 33.8 73.3 34.7 6.4 16.1 0.5 37.4 10.5 43.6 24.7 30.2 22.2 10.2 43.5 14.1 11.1 12.6 11.3 32.4 9.9 4.0 9.4 15.8 12.3 56.2 5.4 20.8 18.6 8.0 7.5 7.5 9.5 7.2 9.1 8.0 7.5 8.6 6.9 8.5 7.5 34.6 48.1 27.3 12.1 23.0 20.1 45.9 51.8 7.4 5.3 5.6 6.7 44.3 18.6 36.8 16.5 25.0 4.0 21.5 9.7 5.9 59.6 0.8 20.8 22.9 38.7 2.4 11.2 6.1 52.5 11.4 33.4 16.8 21.6 37.3 14.8 32.9 11.8 42.4 5.0 8.6 10.3 16.2 37.1 95.4 0.4 18.0 57.3 33.8 13.1 192.3 11.9 19.6 4.5 3.1 83.4 15.0 25.6 27.7 52.4 14.6 30.3 38.0 9.9 26.3 35.2 65.1 1.6 10.4 3.5 10.7 3.0 21.2 30.4 11.2 38.2 ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 142.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.8;Proximal enterocytes: 78.2;Proximal tubular cells: 128.4;Syncytiotrophoblasts: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 97.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" 24.8 71.9 7.6 5.7 8.5 3.3 21.0 7.7 10.1 18.9 8.6 26.9 22.1 6.7 15.8 7.7 9.7 10.8 25.9 7.1 7.0 142.1 36.4 17.8 8.5 8.5 7.3 19.3 6.8 9.9 2.9 15.4 8.0 15.0 17.5 1.1 15.8 16.0 41.3 22.5 20.2 5.4 8.2 8.4 18.8 4.9 7.9 5.6 42.5 25.8 8.2 17.8 13.4 7.7 24.8 8.1 6.6 15.8 68.1 12.1 38.1 5.9 8.6 12.6 24.5 32.1 47.2 15.7 12.6 7.3 11.5 14.7 4.7 29.2 15.3 19.5 11.2 27.3 3.9 58.5 11.4 3.3 24.3 54.9 44.4 15.8 2.1 45.4 17.4 20.3 3.2 8.8 13.7 31.3 8.8 11.1 1.1 47.5 11.9 20.6 4.8 41.2 4.2 97.2 21.6 11.3 11.8 17.3 12.3 13.7 15.5 22.8 12.7 22.5 6.8 3.5 1.9 15.4 3.1 8.2 9.3 17.1 1.4 0.0 2.9 15.3 2.0 7.7 1.7 8.6 1.5 2.1 16.1 2.0 0.7 0.9 0.5 1.6 7.0 6.3 5.5 2.7 7.6 8.5 7.7 10.1 7.1 7.0 8.5 7.3 8.0 8.2 7.9 7.7 3.2 28.9 24.3 27.1 7.3 6.0 23.3 17.0 25.0 0.0 20.8 16.0 25.9 11.5 19.9 3.7 0.0 85.8 1.7 59.5 11.7 13.5 0.4 4.9 3.5 4.9 10.2 1.3 0.3 4.3 11.7 6.5 21.9 7.7 22.2 24.5 4.2 44.4 21.9 0.0 0.3 20.6 2.0 9.8 11.0 1.6 26.8 11.0 3.6 17.8 12.7 6.1 5.2 3.5 0.5 5.7 53.1 14.3 2.6 3.5 78.2 128.4 14.6 0.2 0.0 2.7 5.9 0.2 2.2 5.4 7.0 81.0 4.1 12.1 25.8 14.0 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 626.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 947.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Nuclear bodies,Actin filaments,Cytosol" NA NA 71000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Actin filaments" Cytosol "HPA001873: AB_1078096, HPA006035: AB_1078095" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-2)" "unprognostic (2.37e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.70e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.99e-1)" "prognostic favorable (5.25e-5)" "unprognostic (6.59e-2)" "unprognostic (1.91e-1)" "unprognostic (6.75e-3)" "unprognostic (6.52e-2)" 176.5 160.8 22.9 63.9 42.0 74.2 151.4 42.9 42.2 165.2 58.5 168.5 128.7 269.4 11.8 232.8 163.2 46.8 89.0 19.5 27.8 166.7 85.0 174.7 37.5 45.9 42.4 102.5 90.6 42.2 80.0 85.7 44.8 115.6 42.2 26.0 148.1 59.0 52.2 183.4 150.3 73.1 30.2 118.1 120.9 23.6 38.1 18.5 105.4 18.8 24.2 150.2 181.3 63.4 364.6 947.0 92.9 48.6 37.7 50.6 237.2 198.7 162.5 178.8 143.9 335.9 265.1 99.0 409.1 260.6 117.4 185.1 57.4 203.8 38.3 238.3 69.5 139.7 356.1 240.4 103.4 101.7 145.2 95.3 63.4 157.5 79.6 146.9 116.4 26.3 165.0 71.8 127.5 221.2 27.2 44.1 78.4 197.8 177.3 89.5 109.4 43.8 174.6 396.3 83.0 49.8 366.3 210.5 94.7 64.0 94.5 78.8 309.7 249.3 138.7 135.3 476.1 44.1 84.5 67.8 231.7 90.6 476.7 7.6 8.1 17.8 13.2 7.7 9.8 3.2 5.7 13.2 7.0 3.0 0.9 4.4 16.9 24.8 6.7 10.8 9.5 10.6 22.9 42.0 42.9 42.2 19.5 27.8 45.9 42.4 44.8 30.2 38.1 63.4 315.2 179.5 120.0 21.5 45.8 234.8 266.4 155.1 153.7 25.6 134.0 148.1 9.2 143.0 119.4 152.6 14.6 123.7 150.7 626.1 19.6 413.5 2.5 272.0 145.7 206.2 162.0 59.3 46.0 419.3 256.7 77.3 219.7 346.4 73.5 75.9 130.6 108.5 72.6 23.5 22.6 365.5 73.2 65.9 103.7 4.5 41.3 75.4 46.2 48.7 162.2 122.4 120.5 35.2 83.6 532.3 425.2 71.5 91.2 322.1 315.5 104.0 122.1 32.3 190.7 97.2 251.0 36.2 23.7 189.3 202.7 168.0 119.4 115.3 280.6 284.7 ACTR10 "ACTR11, Arp10, Arp11, HARP11" ENSG00000131966 "Actin related protein 10" Q9NZ32 14 58200080-58235636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000699 Approved "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane, Focal adhesion sites" "HPA000699: " "prognostic unfavorable (3.24e-4)" "unprognostic (4.61e-2)" "unprognostic (6.22e-3)" "unprognostic (2.03e-2)" "unprognostic (4.42e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.71e-5)" "unprognostic (3.20e-1)" "unprognostic (9.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.48e-8)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (2.43e-2)" "unprognostic (8.48e-2)" 12.6 18.0 22.4 3.1 22.4 5.4 12.5 23.4 41.5 15.9 24.5 13.5 2.7 10.2 5.0 16.4 12.7 4.2 22.9 22.2 22.9 18.0 18.5 10.8 4.2 22.3 22.4 15.8 17.4 8.7 20.3 6.4 22.5 14.5 4.4 5.5 10.3 4.7 10.2 13.2 11.3 6.1 22.1 14.7 13.2 10.8 23.0 5.3 13.6 4.1 4.3 12.0 13.9 22.9 4.1 2.6 4.6 1.8 15.3 7.3 2.3 3.1 3.6 4.9 6.1 3.5 4.8 6.3 4.5 6.7 3.0 4.2 6.2 4.5 7.2 3.3 15.3 2.4 4.6 6.9 13.0 4.3 3.4 9.7 6.8 4.5 8.5 4.3 6.7 3.6 2.1 5.0 10.3 11.3 5.7 16.2 2.3 4.0 20.8 4.0 8.0 3.7 9.1 5.2 2.6 2.9 5.9 4.9 16.9 5.2 8.4 7.1 5.4 5.3 11.3 4.9 2.8 2.9 2.0 7.1 5.8 3.3 3.2 15.7 5.4 8.6 6.2 7.3 9.2 6.1 7.0 6.2 4.3 4.1 7.2 7.5 7.8 5.9 8.5 4.8 5.5 4.0 22.4 22.4 23.4 41.5 22.2 22.9 22.3 22.4 22.5 22.1 23.0 22.9 68.3 60.9 44.2 28.7 39.9 53.3 66.4 125.7 34.1 71.4 35.8 43.3 77.0 42.9 75.1 51.5 29.2 110.1 46.4 59.6 125.2 81.2 8.7 40.3 46.7 54.4 33.6 60.0 48.6 59.6 76.9 73.4 32.1 29.7 43.7 49.6 47.8 31.8 77.8 57.2 47.3 48.1 105.8 32.0 38.4 11.6 88.3 47.2 74.7 23.4 52.8 101.4 35.0 40.2 54.6 75.0 29.1 80.1 34.7 59.1 56.3 111.7 67.7 72.0 78.9 54.5 96.6 116.4 60.4 45.7 64.4 156.0 46.1 81.3 41.3 54.6 ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 81.3;Rod photoreceptor cells: 84.8;Spermatocytes: 99.5;Spermatogonia: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: AB_2680298, HPA058795: " "unprognostic (1.65e-2)" "unprognostic (1.53e-3)" "unprognostic (9.80e-2)" "unprognostic (3.15e-3)" "unprognostic (2.46e-3)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (5.83e-2)" "unprognostic (5.90e-2)" "unprognostic (2.68e-1)" "unprognostic (6.85e-3)" "unprognostic (1.69e-1)" "prognostic favorable (7.64e-9)" "unprognostic (2.37e-3)" "unprognostic (8.77e-2)" "unprognostic (5.31e-2)" "unprognostic (2.44e-2)" 6.2 6.6 6.7 4.2 7.1 4.4 5.9 7.6 9.6 3.6 10.2 5.7 5.8 4.3 8.4 4.1 3.3 3.8 20.9 6.3 7.4 11.9 8.2 3.5 4.8 6.7 7.2 3.6 3.6 10.4 6.1 2.7 7.0 6.2 4.8 21.2 4.2 6.4 20.4 2.6 4.6 4.7 6.9 3.8 4.0 11.1 7.1 5.4 10.9 23.4 4.8 4.6 3.0 7.4 6.8 3.4 13.3 15.1 5.5 7.1 6.3 8.1 8.2 12.6 19.3 14.2 3.5 8.0 13.0 8.9 16.7 7.5 0.0 5.7 10.8 8.5 8.0 19.0 23.1 12.0 6.9 0.0 14.8 9.1 10.3 8.5 8.7 8.1 2.7 19.4 21.1 16.2 13.2 4.6 12.3 9.7 5.5 7.8 4.6 15.9 19.9 12.7 11.0 4.1 16.3 11.6 13.1 11.7 12.4 7.2 12.5 12.5 3.7 21.9 10.6 16.6 16.5 16.6 29.9 3.4 12.2 21.2 18.1 5.9 1.4 3.8 2.4 2.0 1.8 2.0 2.2 1.9 2.0 1.6 2.3 2.9 1.1 2.3 1.9 2.9 4.5 1.3 6.7 7.1 7.6 9.6 6.3 7.4 6.7 7.2 7.0 6.9 7.1 7.4 5.9 9.6 10.3 32.7 10.0 7.0 7.4 9.3 7.4 40.7 9.2 9.9 51.2 10.0 6.9 18.4 81.3 7.1 13.3 7.0 58.7 8.9 17.6 10.6 10.3 8.2 7.7 19.1 24.4 8.5 7.0 10.4 5.1 6.8 7.6 15.7 11.0 30.8 8.9 42.1 26.7 7.2 10.2 8.8 7.0 12.7 9.6 8.9 8.8 10.3 5.4 35.5 24.7 19.1 18.3 5.7 1.3 8.6 6.9 7.1 13.0 29.0 10.9 84.8 6.6 11.6 7.3 99.5 82.5 8.8 4.4 2.6 7.0 12.6 11.6 4.4 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADAT2 "DEADC1, dJ20N2.1, TAD2" ENSG00000189007 "Adenosine deaminase tRNA specific 2" Q7Z6V5 6 143422832-143450695 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035479 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 32: Non-specific - Translation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA035479: AB_10611672" "unprognostic (2.24e-1)" "unprognostic (3.07e-3)" "unprognostic (1.55e-1)" "unprognostic (8.20e-2)" "unprognostic (3.05e-2)" "unprognostic (8.58e-2)" "unprognostic (1.07e-3)" "unprognostic (3.31e-2)" "unprognostic (1.34e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-2)" "unprognostic (9.28e-5)" "unprognostic (4.88e-2)" "unprognostic (6.96e-2)" "unprognostic (7.29e-2)" "unprognostic (4.08e-2)" 6.8 8.8 1.4 3.1 1.3 5.4 6.3 1.9 1.5 6.3 1.8 7.8 3.1 4.8 1.4 10.3 6.1 1.2 3.4 1.3 1.2 7.7 12.0 8.5 4.2 1.2 1.2 5.8 10.5 1.5 6.6 1.1 1.3 7.3 4.1 1.4 5.4 1.1 3.1 8.9 8.8 1.7 1.0 10.7 8.9 2.8 1.5 1.9 8.6 0.7 3.5 6.5 7.9 1.4 1.8 1.6 2.2 7.2 1.7 5.3 2.7 2.6 1.1 1.6 2.2 4.0 4.4 7.0 2.7 1.7 1.7 5.8 4.3 4.1 3.4 3.5 9.2 10.4 7.3 8.3 2.1 15.0 4.6 2.4 6.0 3.2 6.3 1.8 3.7 6.5 11.3 5.4 2.7 2.5 6.0 7.6 2.5 2.6 2.8 7.0 5.7 5.6 3.0 1.9 4.7 3.1 2.1 6.0 1.8 1.2 2.4 5.0 3.4 2.6 1.9 5.6 4.8 5.9 4.2 4.9 2.7 13.0 2.8 0.0 0.2 0.0 0.6 0.3 0.8 0.5 0.5 0.5 0.6 0.3 0.7 1.0 0.1 0.4 0.0 0.6 1.3 0.4 1.4 1.3 1.9 1.5 1.3 1.2 1.2 1.2 1.3 1.0 1.5 1.4 4.6 6.4 12.9 8.8 6.9 6.6 4.3 4.1 6.2 3.7 5.6 6.3 4.0 5.7 4.1 1.8 0.0 2.4 11.9 4.3 3.9 5.6 1.2 2.7 11.1 4.8 4.2 14.9 11.2 4.1 2.6 5.3 12.2 5.9 7.6 7.1 3.9 5.2 4.9 1.7 10.4 6.0 4.1 4.3 6.1 1.6 6.8 5.3 5.4 7.5 2.1 1.9 8.2 12.5 4.2 6.6 2.4 3.4 4.2 6.8 1.6 1.4 2.1 4.3 0.0 5.1 5.1 2.4 5.6 9.8 9.2 0.8 8.9 6.2 8.8 4.5 ADD2 ADDB ENSG00000075340 "Adducin 2" P35612 2 70607618-70768225 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.5;brain: 52.8" "Cell type enhanced" "Detected in many" "Early spermatids: 31.7;Erythroid cells: 74.1;Excitatory neurons: 70.1;Horizontal cells: 139.7;Inhibitory neurons: 51.8;Late spermatids: 62.4" "Group enriched" "Detected in many" 5 "glioma: 5.2;testis cancer: 11.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 33.9;JURKAT: 33.1;K-562: 46.5;NTERA-2: 86.7;RPMI-8226: 41.7;SCLC-21H: 42.8;U-251 MG: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009796, HPA034509, HPA034510" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009796: AB_2223572, HPA034509: AB_2674201, HPA034510: AB_2674202" "unprognostic (3.58e-2)" "unprognostic (2.68e-4)" "unprognostic (3.83e-2)" "unprognostic (3.01e-4)" "unprognostic (1.94e-1)" "unprognostic (2.25e-3)" "unprognostic (1.35e-1)" "unprognostic (3.26e-1)" "unprognostic (3.49e-1)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (8.93e-2)" "unprognostic (4.47e-7)" "unprognostic (2.81e-4)" "unprognostic (1.77e-1)" "unprognostic (1.71e-3)" "unprognostic (1.31e-3)" 1.8 1.7 19.5 1.9 21.0 66.5 0.9 14.6 52.8 0.7 0.0 0.9 0.1 0.5 0.3 1.4 0.7 0.3 0.9 18.7 10.8 0.4 0.2 0.9 2.5 14.0 0.2 0.2 1.7 0.2 4.0 0.7 9.5 0.5 0.3 16.0 0.2 0.2 0.8 0.3 0.9 1.0 0.0 1.2 0.3 2.8 0.9 0.7 1.4 1.0 2.2 0.5 0.6 9.6 17.6 20.5 0.8 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 2.7 12.3 0.0 33.9 0.0 0.0 0.1 20.1 1.7 0.2 0.0 0.0 4.7 0.1 0.0 0.0 0.0 0.0 8.0 0.0 33.1 46.5 0.0 0.0 0.1 0.2 1.6 86.7 0.0 0.4 0.0 0.5 41.7 5.7 0.0 42.8 19.3 21.6 0.1 0.1 9.4 0.1 10.7 0.8 0.2 0.9 0.0 47.1 14.1 17.0 0.0 0.7 7.1 7.9 0.0 0.0 0.0 0.0 1.2 0.0 2.2 0.0 0.0 0.0 1.7 0.8 0.4 0.0 0.0 2.3 0.0 0.0 0.3 19.5 21.0 14.6 52.8 18.7 10.8 14.0 0.2 9.5 0.0 0.9 9.6 2.8 0.0 0.5 1.0 4.2 0.1 0.3 0.0 0.0 23.3 0.2 0.0 2.5 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.1 31.7 0.1 0.2 3.9 0.0 74.1 70.1 1.1 0.2 1.0 1.1 0.1 0.0 0.0 2.9 0.0 0.2 139.7 51.8 0.0 0.0 1.0 0.4 62.4 0.9 0.6 1.8 2.8 0.8 0.8 0.0 17.6 1.8 0.3 0.0 0.7 0.1 0.6 0.0 0.0 0.0 8.7 0.0 0.6 0.3 3.5 6.8 0.0 0.1 0.3 0.5 1.5 0.0 1.3 ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.9;lymphoid tissue: 10.5" "Cell type enhanced" "Detected in some" "dendritic cells: 32.0;Microglial cells: 11.2;NK-cells: 43.3;Plasma cells: 16.4;T-cells: 7.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 125.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 39.4;OE19: 13.2;RPMI-8226: 6.2;THP-1: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" 0.3 0.3 0.3 5.0 0.2 1.4 0.7 0.2 0.2 0.2 0.1 1.7 3.7 0.3 0.1 0.6 0.5 0.1 0.0 0.3 0.4 0.0 0.2 0.9 10.5 0.8 0.4 0.0 0.0 0.1 0.2 0.0 0.6 0.3 1.3 0.0 1.3 0.3 0.1 0.1 3.9 0.3 0.6 5.8 0.4 0.4 0.4 1.6 0.3 0.0 10.5 1.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.4 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 3.6 3.6 13.2 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.1 125.9 33.3 0.1 16.9 12.0 4.8 19.1 2.4 8.6 1.2 11.2 0.5 29.9 0.1 68.8 0.2 9.0 0.3 0.2 0.2 0.2 0.3 0.4 0.8 0.4 0.6 0.6 0.4 0.3 0.3 0.0 1.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.8 0.0 0.0 0.0 0.0 0.2 32.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.3 0.0 0.6 0.0 0.3 0.0 3.2 0.0 11.2 1.7 0.0 43.3 0.0 0.3 0.0 0.0 0.0 16.4 0.1 2.9 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 7.1 0.0 0.7 0.0 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 245.3;Inhibitory neurons: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 920000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: AB_2242229, HPA038391: AB_2675990, HPA038409: AB_10675798, HPA075222: " "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.93e-4)" "prognostic favorable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 23.9 15.5 13.0 16.9 18.7 28.6 27.4 13.5 17.7 17.5 11.6 17.9 16.9 10.8 16.5 47.3 16.5 11.4 27.2 13.9 15.2 35.8 151.2 24.4 22.8 14.0 15.0 8.3 18.8 44.2 14.9 26.6 16.5 14.9 19.5 16.1 20.0 16.0 41.5 33.9 12.4 14.8 14.2 15.0 12.1 15.5 14.1 27.0 38.2 47.1 34.5 24.5 24.7 15.8 177.3 37.4 37.2 50.5 37.1 54.7 88.2 140.8 105.4 103.8 114.5 114.0 172.6 86.3 34.2 57.7 51.3 151.1 44.1 150.1 167.0 59.1 51.3 55.6 59.8 122.8 41.7 87.6 22.5 51.1 95.5 77.4 191.7 79.0 91.2 38.7 41.8 28.4 78.8 101.7 102.5 129.0 9.9 80.0 276.3 100.6 63.7 69.4 117.1 92.7 29.5 33.8 63.6 239.7 49.5 34.7 159.7 69.3 82.8 34.3 67.0 93.2 123.0 40.5 48.3 98.1 65.0 127.6 22.1 2.3 34.2 4.1 12.9 65.5 29.9 103.7 28.2 24.1 83.1 155.0 21.3 19.2 11.1 20.7 80.4 57.6 55.7 36.3 13.0 18.7 13.5 17.7 13.9 15.2 14.0 15.0 16.5 14.2 14.1 15.8 9.8 83.3 75.8 136.5 84.2 94.2 73.5 102.0 105.9 16.3 26.2 26.0 67.8 38.6 72.4 31.3 56.3 136.7 25.9 11.0 92.0 83.2 80.7 40.6 18.8 14.9 10.8 27.7 245.3 67.5 139.5 27.0 23.0 55.6 21.5 9.7 17.2 130.1 39.3 11.8 287.7 12.1 44.7 25.2 50.0 26.9 16.8 33.7 48.0 198.6 44.1 14.1 11.3 140.8 165.4 62.7 10.4 12.0 39.1 92.1 5.0 64.5 33.5 25.0 6.6 20.4 26.0 17.4 14.3 96.7 97.0 107.3 32.7 17.0 20.5 66.3 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 ADRM1 "ARM1, GP110, Rpn13" ENSG00000130706 "Adhesion regulating molecule 1" Q16186 20 62302093-62308862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 369.5" "Cell type enhanced" "Detected in all" "Late spermatids: 1655.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 727.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042266 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 28000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA042266: AB_10794044" "unprognostic (5.49e-2)" "unprognostic (5.14e-3)" "unprognostic (7.34e-2)" "unprognostic (6.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-3)" "unprognostic (2.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.13e-3)" "unprognostic (8.98e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (9.02e-6)" "unprognostic (4.15e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "unprognostic (8.47e-2)" 76.9 92.7 44.9 53.4 45.6 78.0 68.3 48.7 63.7 57.8 38.1 78.7 52.0 80.6 14.6 99.0 58.4 33.5 109.0 44.0 48.4 65.1 119.5 67.3 54.2 52.0 45.7 44.5 83.2 23.5 52.6 39.6 51.0 59.5 16.1 11.9 61.3 35.1 369.5 93.9 63.4 23.3 44.4 83.2 68.6 128.5 47.3 38.9 51.7 66.9 29.7 73.0 64.4 46.4 219.9 241.8 66.8 142.6 62.5 45.8 178.1 138.9 95.4 260.1 104.0 727.1 227.8 117.4 250.3 82.1 148.3 243.6 84.3 209.9 79.8 136.7 170.1 284.4 177.4 392.0 105.6 149.3 261.1 57.0 126.3 170.9 67.7 43.4 101.4 113.0 211.4 125.6 61.7 296.1 187.5 290.8 225.1 106.6 354.0 149.2 115.5 186.7 71.3 163.9 118.5 146.5 151.5 241.7 174.0 44.9 168.1 163.3 149.4 258.5 274.4 252.4 289.1 261.5 223.4 158.6 272.6 148.7 192.3 195.4 208.7 233.5 200.4 262.1 179.9 260.2 180.8 192.9 219.2 265.2 132.4 151.4 200.2 184.8 227.8 205.6 265.8 260.8 44.9 45.6 48.7 63.7 44.0 48.4 52.0 45.7 51.0 44.4 47.3 46.4 91.4 35.3 25.2 7.5 91.3 148.2 115.6 275.4 98.4 34.7 62.0 62.0 19.4 52.9 119.3 66.2 18.8 230.4 83.3 156.4 115.4 186.9 359.1 61.7 43.9 105.6 57.8 74.3 5.2 211.3 173.6 73.3 51.0 56.9 42.5 55.8 87.1 101.7 150.2 33.7 4.9 87.1 156.6 77.6 154.2 1655.0 72.4 89.8 97.8 3.7 126.5 73.0 83.4 4.0 8.5 247.5 129.7 86.9 118.2 145.7 118.6 139.0 96.2 31.7 65.7 49.9 177.0 135.2 204.2 108.0 148.0 423.0 86.1 57.5 95.2 144.6 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AEN "FLJ12484, FLJ12562, ISG20L1" ENSG00000181026 "Apoptosis enhancing nuclease" Q8WTP8 15 88621337-88632281 "Predicted intracellular proteins" "Apoptosis, DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 62.7" "Cancer enhanced" "Detected in all" "testis cancer: 38.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048599 Supported "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "Nuclear membrane" "HPA048599: AB_2756313" "unprognostic (8.64e-2)" "unprognostic (1.94e-1)" "unprognostic (2.16e-2)" "prognostic favorable (1.72e-4)" "unprognostic (1.52e-2)" "unprognostic (4.40e-2)" "unprognostic (4.08e-2)" "unprognostic (9.42e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-2)" "unprognostic (9.00e-2)" "unprognostic (7.88e-2)" "unprognostic (8.58e-3)" "unprognostic (3.39e-2)" "unprognostic (2.73e-1)" "unprognostic (8.71e-2)" "unprognostic (6.10e-2)" 9.1 12.2 6.8 10.7 7.1 17.7 6.0 6.6 6.8 6.8 7.0 8.4 5.1 7.6 9.6 9.6 7.0 12.5 7.3 6.3 11.5 9.0 13.5 10.1 12.8 8.6 7.7 8.0 20.9 4.4 22.4 6.9 7.7 12.1 8.6 1.0 8.3 8.2 15.1 7.2 9.1 10.1 8.1 15.2 13.2 9.8 9.5 10.7 10.3 3.7 11.9 11.5 5.9 7.7 14.9 64.5 39.6 34.2 17.4 20.7 83.7 51.5 46.8 39.1 47.8 53.8 28.2 63.6 16.1 28.3 35.0 20.9 148.0 42.1 32.6 15.7 58.2 34.0 26.4 89.9 42.0 28.5 32.8 25.6 36.4 48.5 39.7 14.0 33.0 20.6 54.6 35.2 48.3 34.4 35.5 24.0 96.0 30.8 36.9 45.4 28.2 46.9 16.5 31.9 31.1 28.5 20.8 23.7 40.1 90.7 19.7 32.0 29.9 39.5 55.1 16.2 70.5 67.0 48.5 54.7 36.0 31.5 79.1 0.0 2.3 0.8 6.2 3.7 12.0 10.9 10.8 8.4 5.2 10.3 11.6 10.6 0.6 3.9 4.9 3.1 19.6 9.2 6.8 7.1 6.6 6.8 6.3 11.5 8.6 7.7 7.7 8.1 9.5 7.7 6.9 6.4 8.1 4.2 21.0 18.6 25.8 6.2 12.0 1.2 21.4 15.4 3.9 8.6 12.9 1.8 0.0 4.7 8.4 5.6 3.9 11.4 23.6 22.5 5.3 7.6 9.0 11.8 20.5 7.6 16.3 9.0 11.7 17.7 2.5 12.3 2.5 6.3 4.5 1.7 16.0 9.9 26.4 4.7 26.4 62.7 4.4 7.8 14.2 3.7 14.2 3.1 9.2 9.0 2.5 11.5 6.2 2.6 26.9 27.8 2.3 5.5 5.4 0.9 13.1 12.0 11.6 10.2 18.2 10.9 28.3 6.2 14.9 6.8 9.7 25.4 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826922-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Alveolar cells type 1: 169.9;Breast glandular cells: 119.1;Endometrial ciliated cells: 194.3;Glandular and luminal cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: AB_10599291, HPA030213: AB_10601340, HPA030214: AB_10601005, HPA030215: AB_10601556, HPA049868: AB_2680924" "prognostic unfavorable (7.43e-5)" "unprognostic (2.66e-3)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.09e-3)" "unprognostic (1.75e-1)" "unprognostic (1.73e-2)" "unprognostic (5.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.59e-1)" "unprognostic (4.72e-2)" "unprognostic (5.68e-2)" 39.7 15.0 25.1 23.1 34.8 5.5 49.5 27.2 27.9 46.0 35.1 55.3 53.1 35.8 39.8 126.3 63.8 33.6 47.3 21.0 29.7 45.0 66.8 57.0 10.9 30.2 30.0 31.2 61.2 32.8 38.3 44.9 29.5 47.0 62.7 47.1 79.0 28.6 34.0 54.7 71.1 23.9 12.3 34.2 50.6 31.3 31.2 7.3 51.4 28.4 27.3 29.2 61.8 35.3 67.7 20.7 141.2 50.8 13.5 11.3 104.8 26.8 13.7 22.7 27.9 88.8 41.1 12.0 48.3 16.3 35.5 31.8 59.2 55.1 40.3 76.1 61.1 0.4 9.1 67.9 20.3 7.7 30.8 8.0 36.2 38.1 89.0 36.1 42.8 25.6 137.4 45.5 14.9 29.2 0.8 0.6 34.7 95.6 9.5 43.6 37.1 51.2 41.3 32.5 65.1 39.6 27.2 101.7 40.5 131.1 12.2 2.8 62.9 10.6 50.5 45.7 44.9 0.8 59.3 24.5 31.4 15.4 93.7 0.0 0.1 0.0 0.3 0.1 0.2 1.1 0.3 0.1 0.2 0.7 0.0 0.1 0.9 0.0 0.1 0.0 0.2 0.0 25.1 34.8 27.2 27.9 21.0 29.7 30.2 30.0 29.5 12.3 31.2 35.3 173.8 169.9 89.3 0.0 6.4 0.0 0.0 0.0 0.0 0.0 119.1 83.3 0.0 0.0 40.9 95.6 0.0 30.6 4.7 0.0 21.5 70.1 0.0 194.3 42.0 36.3 0.0 0.0 0.0 39.4 35.0 20.5 0.0 273.4 8.8 65.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 10.9 0.0 0.0 0.0 0.0 65.7 0.0 0.0 4.5 0.0 0.0 35.0 46.7 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 42.1 5.6 13.2 0.0 0.0 AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524305-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus, Vesicles" "HPA034990: AB_2674398, HPA034991: AB_10603577" "unprognostic (7.30e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (8.44e-2)" "unprognostic (3.42e-2)" "unprognostic (4.65e-2)" "prognostic favorable (2.37e-5)" "prognostic favorable (8.44e-4)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.83e-4)" 15.9 20.2 24.6 21.1 24.9 21.3 32.4 31.2 38.4 22.5 28.3 30.5 23.1 18.8 43.7 29.6 22.9 21.9 12.0 25.3 25.6 56.1 33.6 21.9 37.2 24.6 24.6 19.3 31.6 38.0 25.1 15.0 24.5 34.5 33.7 36.8 28.9 18.6 15.4 33.2 24.5 17.3 24.8 26.4 33.7 24.6 25.4 29.3 25.3 12.9 41.4 25.5 22.4 26.2 29.8 19.3 14.1 17.1 17.8 15.1 23.4 16.7 24.9 26.9 20.1 22.4 21.9 43.9 16.0 20.7 31.1 23.5 24.6 23.3 34.8 42.8 13.5 21.0 12.0 26.5 18.8 40.5 34.5 7.5 48.6 17.4 39.6 19.8 21.4 21.8 16.0 38.7 16.8 16.9 21.9 49.1 13.0 55.9 14.3 17.7 22.6 28.8 48.9 31.5 25.9 13.1 17.7 39.9 35.7 18.0 24.0 30.6 18.5 20.0 23.0 17.0 18.8 43.3 27.8 66.7 15.1 45.3 22.6 40.5 9.3 16.6 7.4 9.3 8.7 21.8 9.3 9.1 12.2 20.3 8.8 6.9 16.3 7.1 14.7 15.8 12.8 5.9 24.6 24.9 31.2 38.4 25.3 25.6 24.6 24.6 24.5 24.8 25.4 26.2 24.6 25.6 39.7 43.1 75.4 122.6 29.6 21.5 55.8 24.2 43.8 23.0 16.0 40.0 33.6 20.2 20.9 13.8 40.5 60.7 37.2 25.5 34.8 44.6 17.8 27.1 46.6 52.0 72.1 25.7 12.4 23.6 35.2 55.9 46.9 17.8 17.5 36.8 20.8 37.0 62.9 40.3 20.3 45.2 77.9 55.1 15.8 52.1 23.2 65.6 60.8 35.0 26.8 52.3 67.0 27.3 43.0 20.7 60.5 42.6 29.0 70.5 40.2 32.9 26.3 25.3 21.2 43.1 21.9 59.0 123.5 27.2 36.5 10.2 40.3 46.1 AGAP2 CENTG1 ENSG00000135439 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Q99490 12 57723761-57742157 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 219.9" "Cell type enhanced" "Detected in many" "dendritic cells: 16.4;Excitatory neurons: 22.2;Inhibitory neurons: 12.3;NK-cells: 17.5;Sertoli cells: 32.9;Smooth muscle cells: 16.2;T-cells: 16.4" "Cancer enriched" "Detected in many" 12 "glioma: 20.6" "Region enhanced" "Detected in many" "cerebral cortex: 219.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 40.3;Karpas-707: 39.8;RH-30: 98.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023474, HPA075831" Enhanced Supported "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Midbody ring" "HPA023474: AB_1855378, HPA075831: " "unprognostic (1.87e-1)" "unprognostic (2.46e-3)" "unprognostic (9.26e-2)" "unprognostic (5.56e-4)" "unprognostic (3.95e-1)" "unprognostic (1.14e-2)" "unprognostic (5.00e-2)" "unprognostic (2.36e-2)" "unprognostic (3.39e-1)" "unprognostic (2.80e-1)" "unprognostic (1.93e-3)" "unprognostic (4.18e-1)" "unprognostic (4.81e-9)" "unprognostic (3.30e-1)" "unprognostic (2.72e-2)" "unprognostic (3.07e-1)" "unprognostic (5.75e-2)" 6.3 2.5 85.4 10.0 69.0 14.5 1.8 0.6 219.9 0.8 0.0 2.2 2.9 2.0 0.3 2.3 1.0 4.3 23.5 162.1 0.0 0.8 1.1 3.4 16.9 0.0 0.0 1.5 3.7 1.8 7.5 2.5 0.0 1.9 1.5 4.6 2.3 0.8 15.1 3.2 5.8 1.0 0.0 11.4 3.3 1.0 0.0 15.0 2.5 9.9 11.3 3.2 1.0 38.7 7.3 10.5 19.8 5.8 0.0 0.0 11.3 4.8 0.9 0.1 0.5 1.2 6.6 18.4 1.5 0.0 3.6 4.4 0.1 0.2 0.0 20.3 3.1 20.5 1.6 3.4 0.1 21.2 40.3 0.0 0.0 0.1 0.1 8.4 0.0 21.3 0.0 39.8 0.0 12.6 37.4 13.5 3.2 2.3 10.6 15.5 98.8 13.4 0.0 6.0 5.6 20.5 2.6 3.6 4.3 0.1 2.6 14.8 11.2 5.5 9.0 10.5 3.6 16.8 10.9 9.4 9.8 13.9 9.4 3.8 0.5 0.6 2.7 0.8 2.9 1.2 2.8 3.0 0.8 0.8 1.1 1.7 3.8 1.4 0.4 0.8 4.2 1.1 85.4 69.0 0.6 219.9 162.1 0.0 0.0 0.0 0.0 0.0 0.0 38.7 3.6 3.2 1.1 0.0 5.7 0.0 0.3 0.0 0.0 10.0 0.8 0.5 5.8 1.5 0.6 0.0 0.0 0.1 16.4 0.2 0.0 0.1 0.4 0.1 0.7 4.2 0.0 2.1 22.2 0.0 0.2 0.9 2.0 0.2 2.5 0.0 1.1 0.1 1.3 8.4 12.3 0.5 0.0 2.2 1.1 1.1 0.0 3.0 0.0 1.9 3.9 0.5 17.5 5.0 1.2 0.1 0.1 0.7 11.4 0.3 0.3 0.1 0.0 2.3 32.9 2.2 16.2 0.8 0.4 0.2 0.4 0.0 16.4 0.3 0.2 0.0 AGBL5 "CCP5, FLJ21839" ENSG00000084693 "ATP/GTP binding protein like 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "parathyroid gland: 49.9;testis: 192.9" "Group enriched" "Detected in many" 6 "Early spermatids: 302.7;Late spermatids: 338.0;Spermatocytes: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030981 Uncertain Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Cytokinetic bridge" "Microtubules, Cytosol" "HPA030981: AB_10611673" "unprognostic (1.29e-2)" "unprognostic (8.70e-2)" "unprognostic (2.26e-1)" "unprognostic (3.13e-3)" "unprognostic (1.95e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.86e-1)" "unprognostic (4.34e-1)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-2)" "unprognostic (5.56e-2)" "unprognostic (2.05e-1)" "unprognostic (1.69e-2)" "unprognostic (4.50e-2)" 8.8 16.7 8.4 8.0 7.4 13.6 12.4 7.8 8.2 14.4 9.5 16.2 8.8 14.0 26.0 18.3 20.8 14.3 12.7 7.3 11.3 22.5 7.2 11.2 10.7 8.3 7.8 14.4 15.0 49.9 12.5 11.2 8.9 15.2 11.5 16.3 21.2 16.5 7.1 20.5 9.9 14.6 6.1 8.5 11.8 192.9 9.1 15.6 28.5 6.5 8.6 14.9 7.3 7.5 55.0 34.7 55.4 37.2 11.6 23.0 62.9 10.9 23.5 30.9 31.9 30.2 40.5 30.3 34.0 18.9 43.4 24.6 44.8 49.4 33.9 25.9 66.8 44.5 42.0 65.7 23.6 21.6 14.4 24.4 36.7 27.1 22.0 46.9 32.8 43.5 38.9 23.8 30.3 21.5 63.2 32.3 39.4 39.4 23.7 64.5 62.9 48.0 31.9 13.6 37.1 53.6 21.5 16.7 35.0 53.9 24.9 16.3 16.4 28.6 39.2 13.8 23.9 47.7 27.2 62.4 31.8 24.4 26.1 8.8 1.8 4.5 3.3 1.1 2.5 4.6 4.1 4.6 4.1 2.3 3.6 2.2 1.1 8.5 0.7 2.3 2.8 3.8 8.4 7.4 7.8 8.2 7.3 11.3 8.3 7.8 8.9 6.1 9.1 7.5 3.6 0.0 10.1 5.2 6.3 3.3 8.3 7.2 13.6 5.7 8.6 6.7 6.7 10.0 6.8 9.2 0.0 14.7 1.8 5.9 19.6 8.3 302.7 13.0 3.9 4.9 2.4 11.6 7.9 6.0 7.9 6.4 5.6 5.8 1.3 14.1 6.4 4.1 5.2 0.0 9.1 8.4 6.1 3.1 3.5 338.0 10.5 8.0 7.2 6.5 4.9 6.8 0.0 10.1 10.1 5.0 7.6 11.3 17.1 6.0 6.3 25.0 10.7 10.0 0.0 4.2 7.0 156.8 41.2 16.3 2.7 8.3 5.0 9.4 8.6 10.5 AGER "RAGE, SCARJ1" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 728.3" "Cell type enriched" "Detected in many" 22 "Alveolar cells type 1: 2394.2" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;JURKAT: 3.0;RPTEC TERT1: 2.2;U-266/70: 2.4;U-266/84: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" NA NA 5360000 100000 "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" 2.2 1.7 0.1 1.1 0.1 0.5 1.6 0.1 0.4 4.4 0.2 3.9 0.6 2.5 1.9 2.1 4.5 0.1 2.7 0.2 0.1 6.4 2.7 728.3 0.6 0.2 0.1 4.8 1.7 0.0 5.0 0.4 0.2 4.9 0.8 0.4 1.6 0.0 1.0 2.0 3.2 0.1 0.1 7.0 2.0 2.2 0.2 0.8 39.2 0.1 0.5 2.9 3.2 0.3 0.1 0.0 0.0 0.3 0.1 0.9 1.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.0 0.2 0.0 1.0 0.1 0.3 0.2 0.2 2.5 0.7 0.0 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.1 0.2 0.1 3.0 0.0 0.3 0.1 1.3 0.1 0.9 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.0 0.6 0.8 0.1 2.4 2.0 0.9 1.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 5.4 2394.2 107.9 5.9 4.9 0.9 1.5 2.0 2.8 5.1 1.5 2.9 3.0 4.3 20.9 1.8 0.0 1.1 2.7 1.1 0.0 1.5 0.4 1.1 2.6 4.1 0.0 4.4 0.5 1.0 0.9 3.0 1.5 1.9 17.7 3.1 2.9 2.0 1.3 6.7 0.6 1.3 0.0 5.3 6.5 1.2 1.8 5.3 1.8 4.7 4.8 4.6 2.1 2.5 1.3 1.1 2.7 1.2 3.3 2.6 0.8 0.3 5.6 3.4 6.6 1.2 2.6 0.1 1.2 1.6 1.8 2.2 6.2 1.7 1.2 0.9 AGL ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850361-99924023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 257.6;tongue: 212.0" "Cell type enhanced" "Detected in all" "Muller glia cells: 160.5;Theca cells: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 450000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: AB_2682455" "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favorable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" 11.9 6.7 4.1 7.1 4.9 6.1 9.1 6.9 5.6 6.1 6.0 10.0 8.8 7.3 7.6 16.4 5.4 5.2 22.8 3.7 5.1 13.3 42.8 5.9 7.3 4.7 5.6 5.9 4.3 17.6 4.5 11.7 4.4 13.8 10.6 23.3 7.7 9.6 257.6 5.3 7.1 9.7 4.9 8.0 7.7 4.7 4.8 7.9 10.5 212.0 8.5 8.9 5.0 5.6 20.4 5.9 7.0 11.4 11.0 10.4 23.4 6.3 9.2 5.5 9.8 22.3 6.8 26.4 11.7 10.8 4.9 11.3 40.5 12.4 10.2 14.2 12.9 15.5 18.9 12.4 7.3 13.7 8.9 12.8 7.9 7.5 6.2 7.5 8.5 9.2 26.3 2.0 5.5 6.2 16.3 4.3 10.9 8.9 7.7 0.0 2.3 1.3 16.3 26.7 17.2 12.1 18.2 17.3 9.9 12.8 12.6 9.0 9.4 6.6 9.3 8.9 6.3 7.3 6.1 30.5 11.7 3.6 3.5 0.0 0.4 1.4 1.5 0.6 1.4 1.0 1.1 1.0 0.9 1.0 1.1 1.1 0.5 2.4 0.3 0.8 1.3 0.8 4.1 4.9 6.9 5.6 3.7 5.1 4.7 5.6 4.4 4.9 4.8 5.6 12.8 22.4 26.8 96.6 28.5 10.6 18.1 24.6 18.2 34.6 18.8 18.0 119.6 18.6 25.8 16.5 54.2 107.9 18.8 23.2 23.5 13.7 1.2 18.8 23.6 13.9 16.8 15.6 45.6 12.9 20.3 28.5 31.1 18.6 10.8 45.0 14.6 111.0 17.9 52.2 56.0 15.8 12.2 19.1 8.8 2.5 10.2 13.5 16.0 23.4 14.1 160.5 21.6 36.2 34.4 17.7 14.3 21.4 20.4 13.0 15.2 19.2 26.0 46.9 6.6 41.4 18.4 8.7 11.9 40.0 9.2 29.1 25.7 159.1 23.5 20.1 AGO3 "EIF2C3, FLJ12765, hAGO3" ENSG00000126070 "Argonaute RISC catalytic component 3" Q9H9G7 1 35930718-36072500 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 155.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048342, HPA067849, HPA075436" Uncertain Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Cytoplasmic bodies" "Nucleoplasm, Cytosol" "HPA048342: AB_2680365, HPA067849: , HPA075436: AB_2686750" "unprognostic (4.10e-2)" "unprognostic (7.10e-2)" "unprognostic (4.94e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (1.89e-2)" "unprognostic (2.12e-2)" "unprognostic (4.39e-4)" "unprognostic (5.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.30e-1)" "unprognostic (4.97e-2)" "unprognostic (2.96e-2)" "unprognostic (9.28e-3)" "unprognostic (1.61e-1)" "unprognostic (4.45e-2)" "unprognostic (9.06e-2)" "unprognostic (1.81e-1)" 3.6 2.8 4.5 2.6 8.4 7.4 2.9 6.9 6.9 3.3 7.4 3.0 1.4 2.9 3.2 2.7 2.7 1.9 3.4 4.6 6.9 2.5 4.3 3.5 3.0 8.5 7.2 3.7 2.9 3.3 6.2 3.5 7.4 3.2 2.0 5.1 2.5 2.2 3.2 3.8 2.5 2.7 6.8 2.8 2.8 5.6 8.0 3.3 3.2 4.4 3.1 3.0 3.0 14.0 6.6 4.4 5.5 4.4 7.5 4.6 6.7 5.2 5.4 7.9 8.4 4.9 7.2 7.2 6.5 5.4 9.1 5.3 5.9 3.8 10.5 9.9 3.7 8.8 8.3 3.7 4.0 8.5 7.2 2.2 3.4 11.4 7.2 3.1 6.8 7.4 9.8 10.2 7.0 2.5 6.5 4.6 9.6 3.4 7.8 7.5 7.4 7.1 2.5 6.2 6.7 4.2 9.4 2.3 3.3 8.3 3.5 3.5 5.4 5.5 13.9 4.9 6.4 5.6 10.5 9.9 2.8 5.4 5.4 9.8 4.3 13.2 4.9 4.1 3.1 6.5 3.1 3.4 4.8 6.4 4.4 4.3 13.0 5.4 6.1 4.2 3.4 2.3 4.5 8.4 6.9 6.9 4.6 6.9 8.5 7.2 7.4 6.8 8.0 14.0 32.2 86.6 43.2 80.6 32.6 38.7 35.9 17.8 35.3 69.1 26.1 17.8 19.1 17.2 23.0 25.8 112.6 11.8 36.6 13.2 0.0 15.8 56.0 26.6 43.0 33.8 46.7 18.7 103.8 12.2 14.8 42.3 19.9 35.6 55.9 31.6 36.8 24.7 16.4 42.1 101.1 16.0 20.3 31.7 45.1 76.7 37.9 29.7 23.2 70.3 36.9 35.2 27.8 141.8 155.9 17.3 9.1 41.3 24.7 41.1 15.0 8.8 17.5 89.6 19.7 64.4 29.9 37.5 22.1 20.0 33.5 12.9 35.3 31.0 17.5 27.9 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 51.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 25.5;HEL: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: AB_2682101, HPA060525: AB_2684306" "unprognostic (5.69e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 4.8 2.1 14.7 1.8 30.5 5.2 4.5 24.6 22.5 7.2 5.6 6.4 1.2 7.8 2.2 3.7 6.1 4.2 2.6 14.9 22.7 6.0 0.8 6.7 0.9 47.1 26.3 7.4 2.1 0.3 11.4 8.7 34.3 3.6 2.1 2.2 2.7 2.4 1.0 2.3 2.6 4.7 25.5 4.6 2.3 2.8 28.6 1.3 4.1 1.0 1.0 3.0 5.0 51.3 0.5 1.0 25.5 5.1 4.7 9.5 1.1 0.9 0.3 1.9 3.2 1.5 4.6 0.7 1.8 4.2 11.8 0.5 4.8 4.0 1.8 2.9 8.1 19.4 4.9 0.1 3.7 0.2 2.8 11.4 1.9 5.0 2.7 9.1 6.1 3.1 9.8 8.9 2.4 0.0 1.4 2.2 6.2 0.0 9.7 0.0 1.1 0.5 5.6 0.4 14.8 5.6 4.0 2.1 1.1 9.9 1.1 1.2 6.8 2.6 3.3 1.8 4.4 0.7 1.0 0.0 9.9 1.0 1.6 0.0 1.8 0.0 3.4 1.5 1.1 0.2 1.6 2.1 1.0 0.5 0.8 1.2 0.3 2.9 1.3 0.8 1.7 1.3 14.7 30.5 24.6 22.5 14.9 22.7 47.1 26.3 34.3 25.5 28.6 51.3 12.0 3.2 5.5 7.5 4.5 3.2 5.5 9.7 6.2 2.4 3.5 2.7 5.6 5.7 6.9 5.5 0.0 20.3 31.1 6.1 0.0 5.2 52.1 23.8 12.5 13.5 1.8 31.5 87.9 8.2 12.0 17.8 4.6 5.1 11.4 20.6 10.4 0.2 18.2 0.0 95.8 0.7 10.2 7.2 16.4 72.8 5.9 17.0 3.6 23.4 9.4 4.0 9.2 56.3 407.6 5.5 18.7 8.6 15.7 1.3 0.0 0.6 21.4 1.2 19.7 5.3 6.9 4.9 2.8 1.1 2.6 22.2 14.1 3.7 1.4 3.6 AIDA "C1orf80, FLJ12806" ENSG00000186063 "Axin interactor, dorsalization associated" Q96BJ3 1 222668013-222713210 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027935 Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Cytosol "Microtubules, Cytokinetic bridge" "HPA027935: AB_10602226" "unprognostic (2.33e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (2.63e-2)" "unprognostic (7.28e-2)" "unprognostic (2.58e-2)" "unprognostic (2.26e-2)" "unprognostic (2.73e-1)" "unprognostic (4.43e-2)" "unprognostic (2.09e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.28e-1)" "unprognostic (2.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" 72.3 36.1 53.6 39.1 63.8 21.9 40.2 57.1 66.5 47.8 47.1 50.0 25.3 36.1 56.1 45.2 31.3 40.8 45.8 51.7 62.0 39.3 49.0 46.2 51.2 63.0 58.4 40.6 32.5 32.5 21.4 47.8 62.8 35.1 36.1 19.4 28.0 42.1 28.4 26.6 28.9 54.2 58.9 37.4 28.2 44.3 58.5 33.8 37.5 49.7 52.9 47.2 31.2 69.6 74.3 56.2 65.5 70.4 181.2 169.9 71.4 135.7 145.0 95.1 87.0 64.3 62.0 39.5 67.2 161.7 73.4 44.8 81.4 89.9 115.4 59.6 30.0 50.4 64.2 61.9 95.2 62.5 28.4 104.0 78.9 113.4 108.9 102.4 117.8 49.6 77.1 54.3 180.8 27.6 40.9 38.4 163.6 83.9 118.8 43.8 183.9 57.9 110.9 49.7 43.1 72.1 91.0 53.4 83.8 100.3 43.5 38.5 94.1 127.4 62.9 124.9 162.7 40.3 80.4 35.2 118.1 38.7 128.0 5.7 2.8 2.9 5.7 4.4 4.8 14.2 7.2 6.2 2.5 13.8 7.4 5.8 1.6 3.5 5.0 7.2 10.2 4.1 53.6 63.8 57.1 66.5 51.7 62.0 63.0 58.4 62.8 58.9 58.5 69.6 80.2 22.4 49.9 6.5 57.9 32.5 36.2 19.8 20.5 18.8 20.8 18.0 8.6 27.1 18.7 33.1 33.3 20.6 46.5 19.0 29.4 38.6 20.4 27.1 48.9 52.4 36.1 46.7 8.9 37.9 55.0 52.6 12.8 46.6 3.8 32.4 43.9 36.9 31.5 23.5 11.1 22.4 22.4 37.8 40.2 23.8 60.3 42.5 37.4 30.9 58.9 32.1 38.1 10.6 10.0 51.1 19.8 50.8 32.1 61.2 24.4 54.4 32.8 13.8 32.9 66.1 43.9 35.3 17.9 26.6 30.3 9.0 28.0 32.0 17.8 33.7 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AIM2 PYHIN4 ENSG00000163568 "Absent in melanoma 2" O14862 1 159062484-159147096 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" DNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.5;lymphoid tissue: 50.3" "Group enriched" "Detected in some" 4 "B-cells: 64.2;Early spermatids: 24.0;Late spermatids: 33.3;Plasma cells: 40.1" "Cancer enhanced" "Detected in many" "cervical cancer: 15.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "memory B-cell: 143.8;naive B-cell: 63.7" "Lineage enriched" "Detected in many" 7 "B-cells: 143.8" "Cell line enhanced" "Detected in some" "Daudi: 94.6;HDLM-2: 132.5;Karpas-707: 50.4;U-266/70: 41.7;U-266/84: 34.2;U-87 MG: 38.6" "Low region specificity" "Detected in many" "HPA031365, HPA040309" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nucleoplasm, Cytosol" "HPA031365: AB_10601332, HPA040309: AB_2676925" "unprognostic (6.05e-2)" "unprognostic (7.68e-2)" "unprognostic (4.24e-3)" "unprognostic (2.08e-2)" "unprognostic (6.94e-2)" "unprognostic (3.44e-1)" "unprognostic (3.20e-1)" "unprognostic (1.35e-1)" "unprognostic (4.27e-2)" "unprognostic (1.28e-3)" "unprognostic (7.10e-3)" "unprognostic (1.13e-1)" "unprognostic (1.23e-12)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-3)" 1.2 0.6 0.9 21.6 0.6 1.2 0.9 0.9 0.9 0.6 8.1 2.4 1.8 0.4 0.3 1.6 0.4 2.3 0.3 0.8 0.6 0.5 1.7 1.7 50.3 1.3 0.9 0.2 0.4 0.0 9.8 0.9 1.1 0.9 2.2 0.4 1.3 0.1 0.3 0.6 15.5 0.8 0.8 24.9 3.2 2.5 0.8 4.1 0.7 1.0 49.4 14.0 0.5 0.7 15.8 0.0 0.9 0.0 0.0 12.5 0.0 0.0 1.6 1.1 1.0 0.0 0.0 94.6 0.1 0.0 0.1 0.1 0.0 0.0 1.0 132.5 0.0 3.3 0.1 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 50.4 0.0 0.0 0.0 0.3 0.9 0.0 0.4 0.0 0.0 8.9 0.0 8.3 8.6 0.0 0.2 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.1 17.9 0.3 41.7 34.2 0.8 38.6 3.4 6.7 20.7 8.2 0.0 2.0 7.0 5.4 143.8 5.3 3.5 4.2 63.7 0.5 1.3 16.3 0.0 8.2 0.0 11.9 5.0 0.9 0.6 0.9 0.9 0.8 0.6 1.3 0.9 1.1 0.8 0.8 0.7 0.4 0.0 0.0 0.0 64.2 0.0 0.1 0.2 0.0 0.7 0.1 0.3 0.3 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 24.0 0.0 0.0 0.9 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.4 0.0 0.0 3.2 1.9 33.3 0.3 3.2 3.6 0.0 4.0 0.3 0.0 0.5 0.0 0.1 0.1 0.7 40.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.7 0.4 1.4 0.0 0.0 10.0 0.0 0.0 0.4 AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 185.9;Late spermatids: 275.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome,Cytosol" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "Centrosome, Cytosol" "CAB005361: AB_2302969, HPA070217: " "unprognostic (5.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (8.58e-2)" "unprognostic (8.73e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" 46.0 58.0 18.7 12.5 19.6 11.6 40.0 20.6 27.1 26.1 19.8 40.8 15.2 32.4 21.6 29.7 29.6 7.7 48.4 19.8 20.3 54.9 46.6 29.5 13.0 19.7 20.1 32.6 35.8 11.6 28.6 12.1 19.5 32.9 12.6 23.2 30.9 8.3 79.8 20.6 30.1 9.5 18.7 28.0 36.4 43.3 19.5 13.3 33.0 23.3 12.5 35.5 28.0 20.7 40.3 18.8 28.0 42.6 43.6 26.3 51.1 59.3 18.6 23.8 30.7 56.0 35.5 82.1 54.9 23.4 62.2 14.0 37.2 23.3 40.0 33.1 15.7 40.7 47.8 44.9 33.0 49.5 17.1 14.0 33.3 23.0 37.0 25.0 14.8 45.8 36.6 29.3 28.6 42.1 50.2 31.4 25.0 17.9 10.5 55.8 34.5 44.5 40.3 31.3 14.4 13.3 28.2 26.4 44.6 21.3 25.1 54.7 29.5 20.4 34.6 41.4 47.6 33.1 74.4 75.3 29.8 69.3 28.9 25.2 16.8 20.1 19.2 22.1 20.3 29.8 22.8 24.9 24.8 26.1 24.5 26.3 2.7 24.1 21.0 29.9 25.8 13.3 18.7 19.6 20.6 27.1 19.8 20.3 19.7 20.1 19.5 18.7 19.5 20.7 51.5 22.4 30.0 14.0 33.9 0.0 95.7 0.0 33.6 19.8 57.3 86.6 55.6 18.6 16.7 23.9 10.4 86.7 27.2 16.8 185.9 75.6 174.9 36.4 34.6 38.6 9.7 29.2 14.8 78.5 95.1 47.3 16.8 30.2 21.5 31.7 30.7 42.5 71.3 20.2 15.4 21.3 0.0 30.6 0.0 275.9 33.5 32.2 0.0 6.5 42.4 58.7 34.0 13.0 17.0 59.1 25.5 32.0 29.4 116.6 48.6 149.8 18.2 29.3 52.6 40.9 50.0 56.5 37.9 24.3 0.0 66.2 27.6 44.7 32.9 88.1 AKAP11 "AKAP220, DKFZp781I12161, FLJ11304, KIAA0629, PPP1R44, PRKA11" ENSG00000023516 "A-kinase anchoring protein 11" Q9UKA4 13 42272152-42323261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039089 Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane, Cytosol" "HPA039089: AB_10674279" "unprognostic (6.43e-2)" "prognostic unfavorable (9.26e-4)" "unprognostic (4.91e-1)" "unprognostic (6.89e-2)" "unprognostic (1.92e-1)" "unprognostic (7.34e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (7.91e-2)" "unprognostic (2.15e-3)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (7.49e-3)" "unprognostic (7.44e-2)" "unprognostic (1.49e-1)" "unprognostic (6.02e-2)" "unprognostic (1.10e-1)" 12.6 13.9 14.2 11.5 27.3 3.7 11.6 10.9 19.9 16.6 0.0 10.0 7.5 13.5 15.4 10.6 10.4 10.2 11.6 22.7 12.7 13.3 10.7 10.9 15.8 8.7 15.3 14.7 6.9 11.7 9.3 7.7 8.5 11.3 10.5 32.5 8.0 12.3 5.6 9.9 8.4 12.2 11.5 13.3 10.4 20.6 16.4 13.2 14.0 10.9 13.8 10.4 8.6 18.9 15.2 15.3 18.4 11.0 23.6 28.7 8.0 20.2 16.7 11.9 11.1 16.9 12.4 31.2 7.6 22.7 12.5 17.7 16.1 16.9 22.7 33.4 7.5 8.8 10.6 8.4 18.5 22.2 20.8 21.2 17.0 24.4 21.2 17.5 17.8 15.5 29.5 12.3 24.3 11.4 13.0 7.2 10.9 22.3 7.1 10.7 12.9 15.1 11.9 11.1 7.8 11.3 15.5 10.1 7.1 8.5 8.7 11.8 24.8 20.1 10.4 30.7 15.4 4.7 6.3 15.8 25.7 11.1 14.4 1.7 0.3 0.4 0.5 0.3 0.7 0.9 0.8 0.5 0.3 1.1 0.6 0.6 0.1 1.6 0.5 0.5 1.0 0.2 14.2 27.3 10.9 19.9 22.7 12.7 8.7 15.3 8.5 11.5 16.4 18.9 41.9 25.6 30.5 58.8 42.8 12.2 13.7 15.4 14.8 67.3 20.4 14.6 44.9 12.8 32.6 29.5 37.5 4.4 21.2 12.9 1.9 12.7 14.0 24.3 33.1 25.5 21.0 16.6 105.4 9.5 3.8 27.5 24.5 25.7 34.2 25.9 29.3 22.6 12.5 42.1 105.4 14.9 20.3 24.8 21.6 14.6 21.8 25.0 8.8 46.9 21.6 69.8 16.5 69.9 91.3 12.7 15.4 33.4 27.0 12.2 9.4 20.5 33.1 38.3 19.7 33.9 27.1 49.2 32.8 20.6 16.9 2.5 25.4 28.3 12.3 13.4 AKAP9 "AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO" ENSG00000127914 "A-kinase anchoring protein 9" Q99996 7 91940840-92110673 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 2230.9;Rod photoreceptor cells: 1279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008548, CAB012909, HPA026109" Supported Enhanced "Golgi apparatus,Vesicles,Centrosome" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Vesicles, Centrosome" "CAB012909: AB_2533235, HPA008548: AB_1078121, HPA026109: AB_1844688" "unprognostic (9.57e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (5.97e-3)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (1.31e-2)" "unprognostic (1.28e-1)" "unprognostic (6.59e-2)" "unprognostic (7.59e-2)" "unprognostic (6.32e-2)" "prognostic favorable (2.10e-6)" "unprognostic (8.89e-2)" "unprognostic (1.73e-1)" "unprognostic (7.77e-2)" "unprognostic (3.96e-2)" 7.1 8.3 8.6 6.2 9.0 8.6 11.0 15.3 14.1 6.5 15.5 16.0 16.5 6.4 3.9 7.9 8.4 10.4 6.5 8.6 11.0 13.2 16.2 7.8 5.8 8.8 9.6 11.9 9.5 12.7 8.6 5.4 9.0 7.5 14.6 31.4 9.6 3.8 16.2 6.8 18.6 4.0 7.7 5.0 9.4 4.1 11.9 9.3 9.3 10.0 5.3 5.5 7.2 9.7 11.7 8.1 9.6 5.8 11.6 11.3 6.2 8.7 6.3 4.9 5.9 10.3 8.0 9.2 12.5 7.3 7.5 8.3 10.5 5.6 9.2 9.8 8.2 10.9 11.6 7.3 4.0 18.5 9.6 6.2 6.2 9.1 8.8 7.7 10.3 10.6 19.3 13.0 7.4 14.1 10.4 7.0 8.3 6.5 8.4 7.6 18.2 6.2 4.9 11.5 13.3 11.0 19.0 16.9 10.1 11.1 5.1 9.8 17.5 9.5 11.2 14.5 12.6 7.3 13.0 13.6 6.2 7.8 9.4 1.1 0.6 0.9 1.3 0.6 0.9 1.9 1.1 1.1 0.4 1.6 1.2 1.0 0.7 1.2 0.6 3.2 1.0 0.2 8.6 9.0 15.3 14.1 8.6 11.0 8.8 9.6 9.0 7.7 11.9 9.7 123.3 525.6 357.0 141.3 143.3 103.5 126.5 112.6 170.8 273.5 165.4 150.9 253.2 297.4 208.4 176.6 2230.9 141.4 201.5 293.4 101.8 131.0 22.5 392.3 157.7 115.9 185.1 129.4 142.6 92.6 81.9 123.5 152.9 185.0 136.6 386.1 98.2 153.5 57.2 360.1 182.6 350.8 136.3 78.3 88.4 17.5 173.4 101.6 58.7 115.2 121.5 155.7 119.4 169.9 187.1 102.4 218.9 135.8 193.5 91.4 298.5 47.2 506.3 1279.6 138.1 206.1 116.1 83.0 129.0 87.3 111.8 333.8 145.7 135.8 171.4 97.6 AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 80.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.1;hTCEpi: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: AB_10610980, HPA030271: AB_10600873, HPA030272: AB_10601342" "unprognostic (4.93e-2)" "unprognostic (1.72e-1)" "unprognostic (5.52e-2)" "unprognostic (2.00e-3)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-5)" "unprognostic (8.15e-2)" "unprognostic (5.95e-2)" "unprognostic (2.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.00e-8)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (5.75e-2)" "unprognostic (8.22e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.7 0.0 0.0 1.6 0.0 1.5 0.1 0.0 1.8 2.5 0.5 0.9 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 80.6 0.3 5.1 1.4 0.0 0.0 1.0 0.2 0.8 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.7 0.0 0.0 0.3 17.8 2.5 0.1 1.8 0.0 0.0 0.4 0.0 3.5 3.1 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.9 0.6 1.4 0.1 0.1 0.7 0.1 0.7 0.5 0.0 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 341.5 20.8 9.8 10.0 11.6 1.0 205.6 10.7 12.9 17.4 8.1 37.1 29.6 5.6 3.3 202.5 8.6 98.1 83.8 7.2 16.6 43.0 481.9 23.5 2.1 18.7 13.7 10.4 11.8 1.1 8.1 0.8 17.1 11.7 13.3 15.2 116.5 12.9 286.9 42.5 33.7 9.2 11.5 2.1 137.0 11.8 16.8 4.4 38.3 36.5 9.3 253.9 47.0 9.7 0.0 2054.8 2.4 214.1 2439.5 83.4 0.1 0.7 8.6 0.9 2.0 8.1 0.2 0.4 11.5 14.2 10.0 57.8 0.2 10.7 1.2 0.6 0.2 0.7 516.4 3926.2 4.6 0.4 0.9 218.3 126.4 10.5 10.4 0.7 0.9 0.3 81.9 0.3 20.4 3.3 0.2 0.0 0.7 2684.9 0.8 0.3 0.6 34.6 19.0 1178.9 1.2 0.4 21.2 0.3 0.1 0.4 0.5 4.0 8.6 5.1 1.8 74.6 0.8 0.6 0.6 0.3 25.9 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 11.6 10.7 12.9 7.2 16.6 18.7 13.7 17.1 11.5 16.8 9.7 15.2 12.8 2.8 0.0 0.9 11.9 9.5 141.7 20.5 1.9 0.8 1.4 5.5 102.9 128.8 0.0 0.0 0.0 0.0 10.3 0.0 18.3 17.3 0.7 0.5 7.5 1.8 8.0 2.6 103.3 0.1 44.2 133.5 0.8 0.0 0.1 10.8 397.4 0.1 3.3 4.2 5.4 46.8 12.0 7.8 7.8 79.2 1.0 8.8 19.7 0.6 39.6 0.0 5.5 0.3 90.0 6.6 78.6 0.8 23.7 15.9 3.6 40.3 3.0 0.0 5.3 13.9 0.2 0.3 112.9 13.5 0.0 1.3 0.4 8.5 271.9 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 613.3" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 6.6;OE19: 2.9" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 0.4 41.8 0.0 0.0 0.0 0.3 717.5 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.3 0.2 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 37.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.2 0.0 0.8 0.0 13.5 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 13.6 613.3 0.0 0.0 0.0 0.6 0.0 14.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.2 1.0 1.5 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 AKT2 PKBβ ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 62.8 40.0 31.7 37.3 31.3 48.4 38.6 58.3 40.0 49.8 55.1 42.3 24.5 43.5 49.4 42.5 46.1 25.1 40.8 31.5 24.5 52.2 59.2 30.7 38.1 32.0 26.0 53.9 41.9 58.5 47.8 27.6 26.3 41.2 23.3 41.2 32.5 45.0 101.3 39.4 35.6 34.2 22.1 38.1 33.1 29.7 28.0 53.4 100.1 118.7 37.0 39.8 41.5 35.2 66.2 160.1 63.1 61.5 72.0 88.9 32.5 41.7 63.5 87.6 77.9 71.8 60.8 67.4 36.8 96.3 37.2 28.2 66.8 90.0 56.1 62.5 74.3 43.4 116.5 44.7 45.8 50.7 50.5 82.7 53.6 58.6 56.4 71.9 19.0 73.0 57.3 67.5 49.8 54.6 81.1 24.7 31.7 73.7 41.5 54.2 32.1 48.5 68.3 105.7 82.7 49.8 43.3 75.0 35.0 62.5 59.8 64.9 18.8 52.7 51.5 47.3 67.6 61.5 59.0 56.4 52.6 59.7 44.3 5.7 2.6 2.1 2.2 1.2 2.2 1.9 1.8 1.5 1.7 2.9 1.7 2.6 4.0 1.7 1.6 4.9 1.6 1.7 31.7 31.3 58.3 40.0 31.5 24.5 32.0 26.0 26.3 22.1 28.0 35.2 18.1 16.0 15.9 51.2 33.0 23.8 23.9 20.9 26.2 67.6 25.3 23.9 31.2 30.0 18.1 60.7 41.7 31.3 26.0 23.7 21.5 19.7 5.5 26.2 26.7 17.4 19.2 19.1 30.4 30.4 25.2 27.9 20.9 25.8 14.0 44.2 13.9 87.5 22.3 60.6 25.3 20.1 22.4 23.2 17.5 10.5 42.9 20.0 23.2 23.4 21.7 46.2 50.4 41.7 40.6 24.8 16.9 26.7 30.4 29.7 21.8 24.8 24.9 97.4 19.7 29.3 25.0 14.8 15.6 31.1 27.4 38.7 23.1 56.9 23.3 29.4 AL031681.2 ENSG00000288000 "Novel protein" 20 43458054-43541881 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059648 Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL139300.1 ENSG00000256500 "Novel protein" 14 103562962-103685924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.7;tongue: 16.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;granulocytes: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA044617, HPA052450" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044617: AB_2679024, HPA052450: AB_2681838" "unprognostic (1.56e-1)" 4.3 2.6 0.9 2.9 1.0 0.8 1.3 0.9 5.2 1.2 0.2 1.4 0.0 0.8 0.2 1.6 0.9 0.1 12.8 1.4 1.6 0.5 0.5 1.0 1.6 1.0 1.7 1.0 2.5 7.5 3.8 0.1 1.6 1.4 0.0 3.5 1.6 1.1 31.7 0.6 0.7 3.1 0.7 0.4 0.7 9.4 1.1 2.9 0.1 16.5 1.7 3.4 0.5 1.2 8.1 15.9 18.5 0.6 8.2 7.8 5.6 25.7 19.7 29.3 17.0 9.5 12.1 22.0 17.2 19.2 19.3 5.5 12.4 13.3 17.4 6.7 0.0 8.7 6.1 8.7 9.7 10.8 3.4 8.6 0.6 13.5 11.0 14.5 15.2 13.7 11.6 3.4 21.4 15.4 18.9 1.2 12.1 19.5 13.9 7.7 12.1 11.4 13.6 9.0 22.1 12.2 14.6 5.7 12.1 6.2 13.0 6.6 8.4 11.3 9.2 16.9 10.4 6.4 8.6 25.6 19.6 3.4 9.8 0.2 0.8 1.1 0.5 1.3 0.7 0.3 0.7 0.9 0.4 1.3 1.0 0.4 0.7 0.6 1.6 1.5 1.4 0.3 0.9 1.0 0.9 5.2 1.4 1.6 1.0 1.7 1.6 0.7 1.1 1.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AL162231.1 ENSG00000187186 "Uncharacterized LOC730098" 9 34664163-34666112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 292.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 24.5;Breast myoepithelial cells: 36.4;Collecting duct cells: 36.8;Distal tubular cells: 25.4;Proximal tubular cells: 37.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 18.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 51.4" HPA069617 Enhanced Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Endoplasmic reticulum" "HPA069617: AB_2686161" "unprognostic (8.20e-3)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (6.63e-5)" "unprognostic (2.30e-1)" "unprognostic (2.46e-2)" "unprognostic (9.22e-2)" "unprognostic (2.11e-1)" "unprognostic (2.55e-2)" "unprognostic (5.99e-4)" "unprognostic (8.02e-2)" "unprognostic (1.39e-5)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.08e-3)" "unprognostic (2.00e-2)" 6.0 9.8 49.0 2.9 53.7 2.6 7.8 48.5 76.1 9.3 42.3 9.9 3.9 10.4 19.4 2.4 8.3 2.8 27.8 49.4 50.0 14.6 6.7 5.1 1.9 48.4 46.8 14.0 8.8 6.4 60.6 3.1 48.6 11.7 1.4 6.5 7.3 2.5 36.7 4.6 4.3 2.4 47.8 2.6 6.3 292.4 52.6 2.1 13.6 22.2 0.7 8.0 5.9 49.8 0.6 10.1 9.1 11.9 7.4 3.6 8.2 8.0 2.4 4.9 5.7 1.7 4.0 0.0 1.0 5.4 9.8 2.5 5.9 2.8 0.9 22.1 1.1 0.0 51.4 3.0 1.8 4.5 7.4 3.9 3.1 3.0 3.0 6.8 1.4 12.3 5.5 12.3 3.7 0.0 1.0 4.5 7.7 9.1 2.6 0.0 8.7 1.6 9.3 0.0 9.4 15.2 5.5 1.8 14.0 5.1 4.6 12.5 1.8 17.3 24.0 5.5 1.9 13.1 4.7 1.9 21.4 2.5 24.3 18.2 2.4 2.6 1.8 1.4 1.6 4.4 2.1 0.9 0.8 1.3 2.6 1.3 3.4 4.1 0.8 11.7 2.1 1.3 49.0 53.7 48.5 76.1 49.4 50.0 48.4 46.8 48.6 47.8 52.6 49.8 1.6 9.6 7.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 24.5 36.4 0.0 0.0 2.5 36.8 0.0 13.7 0.4 0.0 25.4 16.2 0.0 7.3 10.4 0.7 0.0 0.0 0.0 10.7 12.1 6.6 0.0 6.0 2.5 5.4 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 5.2 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 37.1 3.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 7.1 1.0 4.0 0.0 0.0 AL357075.4 ENSG00000288520 "Novel protein" G9CGD6 6 154159828-154510114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0" "HPA028708, HPA028710, HPA049651" Uncertain Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 3: HMC-1 - Innate immune response" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: AB_10601916, HPA028710: AB_2732442, HPA049651: AB_2680841" 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.4 0.5 0.5 0.3 0.5 0.7 0.1 1.0 0.4 0.3 0.2 0.0 0.2 0.8 0.6 0.2 0.0 0.3 0.2 0.5 1.4 0.0 0.5 0.3 0.4 0.3 0.1 0.0 0.3 0.0 0.0 0.6 0.6 0.3 0.5 0.3 0.6 0.2 0.0 0.2 0.0 0.4 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.1 0.4 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.2 0.3 0.2 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL358113.1 ENSG00000285130 "Novel protein" 9 69035747-69255187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.6;Endometrial ciliated cells: 3.8;Glandular and luminal cells: 3.8;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "REH: 1.0" "HPA001813, HPA068304, HPA070714" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA001813: AB_1080764, HPA068304: AB_2685970, HPA070714: AB_2732161" 0.0 0.3 0.1 0.4 0.1 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.7 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.8 0.5 0.1 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 3.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.8 0.6 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 AL645922.1 ENSG00000244255 "Novel complement component 2 (C2) and complement factor B (CFB) protein" 6 31927698-31952048 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.5;Club cells: 3.1;Fibroblasts: 1.2;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000951, HPA001817, HPA001832" Approved Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "unprognostic (7.68e-2)" "unprognostic (1.86e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 183.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 21.2 10.4 3.2 31.4 3.2 2.9 8.9 4.1 4.0 8.5 6.4 61.5 22.9 57.7 5.7 32.7 34.9 29.0 14.7 2.7 4.8 59.2 172.7 7.3 5.1 3.5 3.3 12.6 11.3 8.5 2.5 5.2 4.3 36.9 35.5 1.5 11.1 54.5 55.8 6.3 24.8 128.0 3.4 7.2 28.2 8.3 4.0 5.1 15.4 35.9 5.6 85.1 10.5 4.1 72.2 65.5 19.8 31.8 27.6 32.5 15.8 33.6 16.9 27.8 28.3 44.2 13.7 45.2 19.7 47.4 42.0 10.0 66.0 71.4 27.4 50.8 28.5 22.4 44.7 132.2 20.0 36.0 24.0 39.0 15.3 22.6 19.5 56.6 26.8 10.6 65.6 42.8 42.8 27.3 0.1 14.4 59.1 183.3 29.0 14.9 119.9 34.5 25.1 31.7 43.3 19.9 25.7 16.7 19.4 20.6 15.9 27.9 18.2 31.9 52.4 26.9 42.5 6.5 13.2 17.8 16.4 36.0 22.1 0.3 4.2 0.2 6.7 9.2 9.6 5.5 6.5 6.1 9.5 2.6 5.1 6.2 1.0 8.0 11.9 1.2 5.0 5.3 3.2 3.2 4.1 4.0 2.7 4.8 3.5 3.3 4.3 3.4 4.0 4.1 3.3 9.6 1.7 0.0 3.7 1.0 5.7 9.4 2.2 1.2 3.7 4.2 6.6 85.8 3.8 16.5 2.1 2.0 1.2 12.8 17.6 64.1 0.6 2.3 6.4 4.7 15.6 12.8 0.5 6.9 46.6 6.6 8.2 3.4 8.9 12.8 8.9 128.1 7.2 0.0 1.1 25.5 6.1 4.1 2.4 2.2 6.5 4.2 0.0 0.0 5.5 2.1 0.0 0.5 0.5 15.0 7.7 6.8 3.7 6.1 10.3 165.0 0.3 0.7 0.0 6.0 16.1 0.6 0.8 2.1 1.0 1.8 3.3 91.7 71.7 2.8 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 ALKBH5 "FLJ20308, OFOXD1" ENSG00000091542 "AlkB homolog 5, RNA demethylase" Q6P6C2 17 18183078-18209954 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 236.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007196 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA007196: AB_1850461" "unprognostic (1.07e-1)" "unprognostic (1.51e-1)" "unprognostic (2.23e-2)" "unprognostic (1.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.64e-1)" "unprognostic (1.34e-1)" "unprognostic (1.94e-2)" "prognostic favorable (3.75e-4)" "unprognostic (6.54e-2)" "unprognostic (3.99e-2)" "unprognostic (2.88e-2)" "unprognostic (3.22e-2)" "unprognostic (4.68e-3)" "prognostic unfavorable (5.69e-4)" 33.4 40.1 23.7 21.4 21.8 32.6 29.2 18.1 23.5 34.2 17.8 51.1 22.3 45.3 5.2 25.9 43.1 21.6 68.6 20.4 23.4 29.9 33.6 28.8 25.1 23.2 23.7 33.5 36.0 26.6 39.8 17.4 29.5 31.7 10.6 26.5 36.4 25.1 236.6 28.1 31.0 22.0 19.3 26.8 33.6 51.3 26.7 22.2 29.8 98.7 15.8 43.0 29.6 27.4 90.3 86.4 27.8 47.0 37.0 25.0 30.1 41.1 41.8 56.8 51.5 96.1 19.9 53.9 65.4 35.9 29.4 56.2 40.9 33.6 26.8 71.3 74.0 35.4 47.7 41.8 32.5 27.4 53.0 24.3 23.1 41.8 24.7 33.9 31.8 35.3 45.0 20.4 29.8 60.6 60.1 28.6 24.9 28.3 44.4 57.6 56.0 89.0 14.4 31.0 32.5 47.6 44.8 27.2 41.7 90.9 31.4 20.9 38.3 55.8 44.1 87.8 78.0 32.0 25.1 32.2 100.6 38.8 39.0 3.6 7.4 20.4 13.0 7.8 11.9 6.8 13.3 16.1 9.0 10.0 9.5 9.5 4.3 7.2 11.6 5.7 7.4 6.7 23.7 21.8 18.1 23.5 20.4 23.4 23.2 23.7 29.5 19.3 26.7 27.4 37.2 35.3 33.3 17.9 41.1 64.6 29.0 26.8 19.4 80.3 48.7 40.3 93.5 28.6 24.4 27.6 39.6 33.0 59.0 44.9 84.1 27.4 58.9 53.9 36.5 36.6 60.9 24.0 17.0 31.4 44.8 42.4 18.3 36.7 40.7 25.2 35.7 65.2 33.5 119.5 18.1 45.0 22.4 45.3 56.9 42.5 41.0 36.4 49.8 7.5 36.3 76.3 57.7 9.0 24.0 32.8 38.7 51.9 21.1 35.3 47.6 115.2 46.4 58.9 19.7 39.4 47.3 118.7 117.3 20.3 56.0 31.5 48.3 32.7 39.1 28.6 ALMS1 KIAA0328 ENSG00000116127 "ALMS1 centrosome and basal body associated protein" Q8TCU4 2 73385758-73625166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Cone-rod dystrophy, Deafness, Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 68.4;Excitatory neurons: 64.9;Late spermatids: 86.6;Oligodendrocytes: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RH-30: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035277, HPA043200" Enhanced Approved "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles, Centrosome" Cytosol "HPA035277: , HPA043200: AB_10796689" "unprognostic (2.86e-1)" "unprognostic (9.67e-2)" "unprognostic (2.58e-2)" "unprognostic (4.50e-3)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (2.91e-3)" "unprognostic (7.73e-2)" "unprognostic (1.02e-1)" "unprognostic (8.58e-2)" "unprognostic (4.78e-2)" "unprognostic (1.84e-1)" "unprognostic (3.43e-2)" "unprognostic (1.63e-1)" "unprognostic (7.85e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" 2.6 2.4 5.3 2.4 6.8 5.5 4.3 16.0 5.2 4.1 4.5 3.1 2.3 4.5 4.7 1.9 6.4 2.5 1.6 5.3 4.8 3.5 2.4 3.1 3.2 6.8 6.4 9.8 4.5 4.8 1.7 2.7 6.0 3.5 3.0 10.4 2.9 3.6 0.8 2.9 1.9 3.6 5.1 2.4 2.9 22.2 5.7 8.7 4.6 3.1 2.9 2.6 1.5 7.8 14.3 4.6 9.0 8.2 6.2 5.8 6.7 4.8 5.0 6.2 4.8 4.8 1.5 13.8 3.3 6.7 8.0 6.5 12.3 4.2 8.3 6.7 4.1 7.9 4.4 10.2 4.1 10.9 3.8 4.5 3.7 7.6 3.9 3.9 6.3 9.3 7.4 4.9 7.1 7.0 10.2 14.3 10.6 5.7 3.9 10.8 32.5 5.1 4.1 3.7 7.1 10.0 9.1 1.5 5.2 7.5 1.7 2.5 5.4 8.2 8.3 7.1 11.7 6.6 4.0 10.4 3.7 8.2 4.0 0.2 0.0 0.5 0.2 0.1 0.1 0.2 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.2 0.1 0.3 0.2 0.0 5.3 6.8 16.0 5.2 5.3 4.8 6.8 6.4 6.0 5.1 5.7 7.8 7.3 6.4 10.3 48.3 5.6 2.4 3.1 2.6 6.8 23.3 4.7 4.8 7.2 7.2 9.1 11.0 25.0 3.3 12.8 4.4 0.0 4.7 68.4 30.6 13.2 8.0 7.3 15.4 64.9 3.7 2.7 8.9 10.7 9.3 5.1 21.8 4.6 2.2 3.3 21.9 55.8 5.2 0.0 3.1 2.7 86.6 8.1 6.3 3.6 31.9 5.3 9.2 5.2 54.3 92.7 3.4 1.3 9.1 10.2 3.2 4.0 1.7 25.2 39.7 6.6 14.8 9.5 30.6 26.7 6.9 3.3 1.9 7.8 11.5 5.3 2.0 ALOX12 12S-LOX ENSG00000108839 "Arachidonate 12-lipoxygenase, 12S type" P18054 17 6996049-7010754 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.6;esophagus: 49.4;vagina: 105.7" "Cell type enriched" "Detected in some" 6 "Macrophages: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "A-431: 25.5;HEL: 40.4" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.4" "HPA010691, CAB019287, HPA064819" Enhanced Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 49000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Vesicles" "CAB019287: , HPA010691: AB_1844756, HPA064819: " "unprognostic (3.61e-3)" "unprognostic (6.93e-2)" "unprognostic (7.17e-5)" "unprognostic (9.43e-2)" "unprognostic (6.06e-2)" "unprognostic (2.25e-3)" "unprognostic (2.45e-1)" "unprognostic (3.16e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.96e-5)" "unprognostic (4.01e-3)" "unprognostic (2.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" 1.0 1.5 0.9 3.2 1.5 4.7 0.3 0.1 1.4 34.6 0.6 0.4 1.8 2.2 0.0 49.4 1.2 3.1 1.4 0.4 0.4 0.5 0.2 1.1 3.9 1.3 0.7 1.3 1.9 0.0 0.1 1.1 1.0 0.8 0.1 3.1 20.2 0.0 1.6 21.7 2.0 0.2 0.1 3.3 1.1 1.3 1.2 0.0 1.9 0.1 3.8 1.5 105.7 3.4 25.5 4.2 1.9 1.4 0.0 0.0 1.7 1.6 0.0 0.0 0.0 3.7 0.9 1.3 0.9 0.0 1.4 3.2 0.0 0.1 0.0 2.8 3.2 40.4 6.8 2.8 0.1 0.4 6.5 0.0 0.1 0.0 0.0 2.4 0.0 2.8 2.7 1.4 0.0 0.3 0.5 0.9 1.3 0.2 0.8 1.4 0.8 0.7 0.0 3.2 0.1 0.9 0.7 0.8 0.4 2.4 1.5 1.1 4.6 2.2 1.2 2.1 1.1 0.8 0.3 0.7 1.2 3.0 1.0 2.1 0.9 1.8 0.7 0.4 0.5 1.1 0.5 0.7 0.7 0.6 0.2 0.3 4.5 0.7 0.4 1.3 0.3 13.6 0.9 1.5 0.1 1.4 0.4 0.4 1.3 0.7 1.0 0.1 1.2 3.4 0.0 0.0 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 17.3 0.0 1.0 0.8 0.0 0.0 2.5 2.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.5 1.1 0.0 0.1 0.1 0.0 2.0 ALX1 CART1 ENSG00000180318 "ALX homeobox 1" Q15699 12 85280220-85301784 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.9;kidney: 6.1" "Cell type enriched" "Detected in some" 5 "Melanocytes: 32.0" "Cancer enriched" "Detected in some" 10 "melanoma: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 10.4;HEK 293: 23.3;HUVEC TERT2: 17.2;SK-MEL-30: 29.5;THP-1: 18.0;WM-115: 14.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001598, HPA018905" Uncertain Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Golgi apparatus" "HPA001598: AB_1078400, HPA018905: AB_1844783" "unprognostic (4.92e-3)" "unprognostic (8.09e-2)" "unprognostic (1.09e-3)" "unprognostic (1.84e-1)" "unprognostic (6.24e-2)" "unprognostic (2.05e-2)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-5)" "unprognostic (8.97e-2)" "unprognostic (1.43e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.3 1.0 0.4 0.0 0.0 0.7 3.9 0.0 2.3 0.0 0.0 0.2 0.3 6.1 0.0 0.0 0.0 0.2 0.2 1.6 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.2 1.9 0.9 0.0 1.6 0.0 0.3 0.2 0.0 0.0 0.8 0.2 0.0 0.0 0.8 0.0 0.4 0.3 0.2 0.0 6.0 0.0 0.0 0.7 0.7 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 3.6 0.0 10.4 0.5 0.0 0.0 23.3 0.0 4.1 0.0 0.3 0.0 0.0 0.0 0.0 3.1 0.0 9.3 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.7 5.8 0.0 0.0 29.5 4.1 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 2.2 0.2 1.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7;skeletal muscle: 27.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 132.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 46.6;HMC-1: 47.7;Karpas-707: 61.2;SiHa: 40.5;SK-BR-3: 46.1;U-266/70: 49.1;U-266/84: 62.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.8 11.7 8.2 6.5 11.2 6.1 0.4 5.5 11.8 0.3 6.9 1.4 5.1 3.0 0.4 2.6 0.7 1.7 1.7 7.6 6.9 5.8 60.7 2.3 4.4 15.5 8.6 1.4 3.3 0.7 0.5 2.0 9.5 2.8 0.2 1.8 2.0 0.2 27.3 5.8 5.0 0.6 2.7 5.9 4.8 13.1 8.0 0.6 0.9 0.9 0.4 0.3 0.2 15.4 46.6 9.5 0.8 5.8 0.0 0.0 10.0 1.5 0.5 0.7 1.4 3.9 5.8 4.0 4.2 0.0 2.6 8.2 0.3 0.0 0.3 16.0 1.7 4.2 7.9 9.4 0.0 5.9 47.7 0.0 0.4 0.8 0.1 0.2 0.3 3.9 2.7 61.2 0.0 6.8 3.7 10.8 4.4 1.8 2.2 7.8 0.3 5.3 0.0 4.3 4.9 6.9 40.5 46.1 5.2 0.2 4.6 8.4 0.0 5.8 19.1 8.0 5.4 49.1 62.8 6.3 3.8 12.2 6.9 0.2 0.6 1.7 0.5 0.6 0.4 0.6 0.2 0.6 0.5 0.3 0.3 0.4 0.4 2.3 1.8 0.2 0.1 0.5 8.2 11.2 5.5 11.8 7.6 6.9 15.5 8.6 9.5 2.7 8.0 15.4 1.1 0.0 0.5 0.3 2.0 0.4 0.2 0.0 0.0 0.1 1.1 1.0 0.6 1.5 0.6 3.7 0.0 0.9 1.7 0.0 3.9 0.2 0.9 0.1 0.0 0.8 1.8 8.0 0.7 1.1 0.1 0.1 0.0 0.0 0.0 0.2 8.6 132.5 4.4 1.7 0.3 0.1 0.0 5.7 1.3 0.1 0.3 1.8 3.6 0.0 0.7 1.8 2.1 4.0 2.0 0.2 0.0 0.0 0.7 0.0 0.4 31.0 0.0 0.0 0.0 0.8 0.0 1.5 1.9 0.0 0.3 0.3 1.4 0.3 0.4 0.1 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 AMER3 "FAM123C, FLJ38377" ENSG00000178171 "APC membrane recruitment protein 3" Q8N944 2 130755540-130768134 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 14.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.2;Enteroendocrine cells: 15.1;Excitatory neurons: 6.6;Horizontal cells: 3.3;Inhibitory neurons: 5.7;Rod photoreceptor cells: 4.9" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA045593, HPA054230" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA045593: AB_10965021, HPA054230: AB_2682423" "unprognostic (6.68e-2)" "unprognostic (3.73e-1)" "unprognostic (2.17e-2)" "unprognostic (1.83e-1)" "unprognostic (2.71e-1)" "unprognostic (5.33e-3)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (6.46e-3)" 0.0 0.6 4.0 0.0 4.5 0.1 0.0 14.6 8.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.2 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.9 0.0 2.8 0.0 1.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 4.5 14.6 8.1 3.7 3.2 1.2 0.2 1.0 0.0 1.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.1 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.7 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 41.5;ovary: 33.1" "Group enriched" "Detected in some" 4 "granulocytes: 26.0;Granulosa cells: 36.1;Theca cells: 94.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HEL: 40.1;K-562: 22.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 11 "hippocampal formation: 9.4" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.6 41.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.1 0.5 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.2 33.1 12.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 4.2 0.1 0.1 0.0 0.0 5.7 0.7 9.1 0.5 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 40.1 0.0 0.8 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 3.5 2.6 0.0 0.1 1.5 0.0 4.2 0.1 2.1 0.1 2.7 0.0 0.1 26.0 36.1 11.4 0.3 0.1 0.0 0.0 0.0 0.0 1.2 0.0 2.5 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.3 0.0 0.0 0.3 0.8 94.9 0.1 0.0 AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Enteroendocrine cells: 60.4;Glandular and luminal cells: 72.8;Granulosa cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 192.0;fHDF/TERT166: 183.2;hTERT-RPE1: 312.2;LHCN-M2: 179.2;RT4: 251.9;U-2 OS: 149.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 32: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" 10.8 19.8 4.5 7.0 4.9 3.5 22.8 3.6 5.4 20.3 2.3 39.4 3.3 30.7 7.9 4.0 36.4 19.3 5.6 3.2 8.8 7.7 4.6 20.0 12.4 9.1 37.9 28.7 3.6 6.4 5.3 13.2 19.6 11.3 9.0 25.7 4.5 11.0 1.1 4.4 12.6 34.3 4.3 17.4 5.5 10.7 13.1 2.8 4.2 2.2 7.6 22.6 14.3 3.9 44.4 105.5 6.3 0.2 2.5 0.2 17.2 14.8 39.3 4.7 3.8 0.3 192.0 0.0 47.6 183.2 117.0 64.8 0.0 117.6 5.5 8.6 0.7 0.0 11.0 0.1 3.8 1.2 1.7 0.9 20.1 122.6 59.5 312.2 15.0 0.9 8.5 0.0 179.2 2.1 3.6 0.1 4.5 21.2 27.1 0.3 46.5 0.1 52.3 251.9 18.8 0.0 76.2 9.0 0.5 3.4 11.2 1.0 4.1 2.6 149.9 1.7 121.3 1.9 0.4 0.2 10.0 3.4 2.8 0.0 0.1 0.0 4.4 0.2 6.0 3.7 6.8 6.9 0.7 1.6 15.3 12.1 0.1 8.6 0.0 8.8 4.4 4.7 4.5 4.9 3.6 5.4 3.2 8.8 9.1 37.9 19.6 4.3 13.1 3.9 7.2 9.6 3.1 1.0 3.6 2.4 13.1 39.4 15.4 62.6 10.8 37.7 1.6 1.5 4.9 1.8 0.0 1.0 12.4 0.4 1.9 5.3 1.4 31.5 6.0 12.7 60.4 5.7 2.6 19.3 28.1 11.1 0.5 72.8 7.0 76.8 32.2 1.2 4.8 0.0 0.2 3.1 2.0 3.5 1.1 2.3 2.5 7.2 1.8 1.9 5.3 15.6 2.1 0.0 0.1 40.4 1.5 0.7 3.8 10.7 0.0 0.1 2.9 4.9 0.0 3.2 27.7 0.7 2.4 2.5 0.4 8.5 7.6 12.8 0.3 33.9 AMZ2 ENSG00000196704 "Archaelysin family metallopeptidase 2" Q86W34 17 68205481-68257712 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 477.3;Early spermatids: 736.8;Late spermatids: 1665.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023299, HPA052406" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023299: AB_2226909, HPA052406: AB_2681818" "unprognostic (3.04e-1)" "unprognostic (3.68e-2)" "unprognostic (3.93e-2)" "unprognostic (3.27e-3)" "unprognostic (3.32e-1)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (2.43e-1)" "unprognostic (3.92e-2)" "unprognostic (2.83e-3)" "unprognostic (3.59e-3)" "unprognostic (3.37e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.37e-1)" "unprognostic (2.95e-1)" "unprognostic (3.28e-1)" "unprognostic (7.62e-2)" 52.3 51.8 54.5 32.6 66.4 36.4 45.0 57.1 87.2 41.2 50.0 57.8 26.2 44.5 53.4 38.4 52.5 37.9 77.0 59.5 56.6 59.2 38.1 32.9 54.0 58.8 56.7 48.7 45.3 64.4 59.1 29.5 58.0 41.6 32.9 78.5 40.0 51.2 95.6 43.1 36.9 41.7 55.3 43.3 39.7 194.4 60.0 53.2 53.3 86.8 51.7 48.5 36.5 61.4 94.6 98.9 87.5 72.9 65.6 113.4 140.0 71.0 88.3 116.1 93.7 42.3 60.4 142.6 74.9 104.8 107.0 46.0 68.6 198.5 154.0 50.2 67.7 52.8 38.6 83.1 124.9 49.8 86.9 96.9 213.9 107.5 206.2 113.0 118.9 121.7 54.6 86.5 150.9 67.3 110.2 45.4 43.5 51.1 98.5 41.3 238.9 106.7 71.2 50.1 85.7 67.2 64.8 125.5 130.9 184.6 100.7 33.5 65.2 143.8 72.0 55.8 74.8 121.9 121.9 255.7 105.1 69.0 79.1 76.6 25.2 35.3 34.8 30.3 46.2 30.7 43.2 46.0 30.3 41.3 37.8 40.4 45.1 63.7 40.9 28.1 58.3 36.9 54.5 66.4 57.1 87.2 59.5 56.6 58.8 56.7 58.0 55.3 60.0 61.4 18.5 12.8 15.6 477.3 38.7 18.6 31.6 58.4 30.1 13.8 29.7 34.3 81.4 21.5 32.8 23.9 8.4 64.0 58.0 9.4 109.5 28.8 736.8 28.4 17.2 24.4 21.1 21.0 36.4 26.0 66.9 28.2 14.8 18.5 34.1 28.9 21.4 15.5 41.8 18.5 30.0 16.7 40.7 26.1 71.0 1665.0 36.1 39.0 56.9 27.2 46.4 65.7 69.0 56.8 47.7 25.4 10.8 32.7 46.2 17.7 15.2 69.0 61.8 12.8 19.7 26.5 26.8 274.4 59.4 26.4 22.6 34.2 49.3 26.1 15.1 24.5 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGEL2 "Ccr4d, FLJ12793, KIAA0759L" ENSG00000174606 "Angel homolog 2" Q5VTE6 1 212992182-213015867 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030795, HPA030796" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Mitochondria" "HPA030795: , HPA030796: AB_10600979" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (8.73e-2)" "unprognostic (2.76e-1)" "unprognostic (2.04e-2)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (2.70e-3)" "unprognostic (6.46e-2)" "prognostic unfavorable (8.39e-6)" "unprognostic (9.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.20e-4)" 7.5 6.6 13.1 6.9 14.9 6.4 10.4 11.1 14.7 7.9 9.2 6.6 5.2 8.6 8.1 5.9 7.4 6.1 5.8 12.8 11.1 7.7 8.0 6.6 10.5 10.6 10.8 10.8 6.7 7.8 6.2 6.5 10.1 8.2 6.4 9.2 6.0 6.2 7.3 9.1 7.2 7.1 10.1 9.8 6.3 5.5 13.1 10.2 8.1 7.1 9.2 7.1 6.3 11.6 12.2 9.6 15.2 13.2 11.5 16.8 13.6 9.8 16.3 15.4 15.3 6.3 8.9 11.8 8.8 9.7 8.5 9.4 17.8 9.4 15.5 22.3 10.6 11.9 7.4 6.3 12.5 11.8 13.6 10.4 11.9 12.1 12.2 13.1 13.2 10.4 13.9 11.8 18.0 4.0 13.6 7.9 36.4 6.6 6.8 6.9 27.4 12.4 12.1 8.2 7.5 21.7 11.9 15.7 18.3 16.2 12.2 8.6 9.8 12.7 6.7 15.7 15.1 8.6 8.9 7.9 14.2 8.7 11.9 6.6 4.4 5.9 5.1 4.3 6.5 5.7 6.4 5.4 5.5 3.5 6.7 5.7 2.7 10.9 3.5 3.3 8.9 5.2 13.1 14.9 11.1 14.7 12.8 11.1 10.6 10.8 10.1 10.1 13.1 11.6 23.1 48.1 9.8 26.8 23.8 6.9 8.5 11.7 12.5 21.2 14.6 10.2 15.2 17.2 14.5 12.9 10.4 14.8 26.2 7.6 11.7 10.3 1.5 11.3 19.8 15.9 6.7 18.1 33.2 10.5 15.0 18.0 14.3 11.7 17.1 28.8 16.1 12.5 11.8 28.6 26.3 8.4 14.2 20.4 10.5 2.6 15.5 17.1 3.6 30.0 17.3 11.6 16.5 30.2 49.3 10.2 6.4 13.9 24.2 10.8 10.7 16.9 22.5 17.8 19.7 21.7 16.1 9.5 16.6 12.7 7.0 10.9 25.8 17.9 8.0 7.4 ANKEF1 "ANKRD5, dJ839B4.6, FLJ21669" ENSG00000132623 "Ankyrin repeat and EF-hand domain containing 1" Q9NU02 20 9986126-10058303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.0;testis: 14.6" "Group enriched" "Detected in many" 21 "Early spermatids: 323.1;Late spermatids: 383.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/84: 14.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA041151 Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" "Nucleoli fibrillar center, Plasma membrane, Cytosol" "HPA041151: AB_10796569" "unprognostic (4.72e-2)" "unprognostic (9.86e-2)" "unprognostic (2.31e-2)" "unprognostic (2.09e-1)" "unprognostic (5.38e-4)" "unprognostic (2.54e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (1.81e-4)" "unprognostic (3.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.28e-1)" "unprognostic (6.73e-2)" "prognostic favorable (4.44e-4)" "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.11e-1)" 2.4 1.4 1.1 1.5 1.1 0.6 3.1 2.7 1.4 2.2 2.8 2.5 2.5 1.0 1.0 2.5 4.0 2.2 1.0 0.9 1.7 2.5 4.0 1.7 1.2 1.4 1.3 2.2 14.0 4.3 2.2 0.7 1.4 1.9 2.3 5.3 2.6 2.1 0.6 2.8 2.4 0.7 0.9 1.2 3.7 14.6 1.6 1.7 5.7 0.6 1.8 1.6 1.3 0.9 9.0 8.7 0.9 2.1 2.2 1.5 5.9 1.3 0.1 1.6 0.8 5.1 7.2 0.1 2.4 0.3 9.7 7.1 2.3 9.0 1.9 0.0 1.4 1.1 2.2 5.3 1.0 0.9 0.2 3.9 9.8 1.5 1.4 4.0 1.4 3.2 3.4 6.1 0.4 2.4 1.4 0.0 4.4 11.2 2.4 0.0 0.1 5.6 5.3 5.5 6.5 3.1 3.8 8.7 0.0 3.2 7.2 0.8 0.9 1.1 1.4 0.1 1.4 7.0 14.2 1.3 2.4 0.4 1.2 0.0 0.0 0.0 0.7 0.0 1.1 0.5 0.7 0.5 0.0 0.4 1.0 0.6 0.1 0.5 0.0 0.5 0.7 0.2 1.1 1.1 2.7 1.4 0.9 1.7 1.4 1.3 1.4 0.9 1.6 0.9 0.5 3.2 6.7 1.3 2.0 0.3 2.3 1.6 3.4 1.7 3.4 1.8 1.8 2.8 2.0 7.3 0.0 2.2 1.2 2.7 1.9 4.5 323.1 6.7 1.0 1.8 5.3 0.4 1.1 6.3 2.0 0.9 10.7 2.8 1.3 0.7 0.7 9.1 1.3 3.3 2.8 3.8 2.0 0.3 0.6 383.0 3.4 1.4 0.0 1.0 0.0 0.8 3.1 0.5 0.4 5.3 4.2 4.1 4.8 1.9 3.3 2.8 16.2 4.9 0.0 0.7 0.3 5.1 3.4 8.6 0.3 1.5 2.6 1.1 3.7 1.5 ANKMY1 "FLJ20499, ZMYND13" ENSG00000144504 "Ankyrin repeat and MYND domain containing 1" Q9P2S6 2 240479422-240569209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 67.9" "Cell type enhanced" "Detected in many" "Early spermatids: 187.5;Late spermatids: 213.1;Respiratory ciliated cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA026620, HPA048869" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026620: AB_1844834, HPA048869: " "unprognostic (2.89e-3)" "unprognostic (1.03e-1)" "unprognostic (3.83e-2)" "unprognostic (3.22e-3)" "unprognostic (3.46e-1)" "unprognostic (3.97e-5)" "unprognostic (8.32e-2)" "unprognostic (1.19e-1)" "unprognostic (4.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.36e-2)" "unprognostic (2.59e-5)" "unprognostic (2.01e-1)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.20e-4)" 4.9 4.4 6.4 5.7 7.6 12.5 6.3 6.0 7.3 7.5 6.1 6.0 6.5 5.4 8.7 5.8 24.6 4.7 3.4 5.4 4.9 5.0 6.2 6.9 9.0 8.1 12.3 7.4 8.6 6.2 4.5 3.9 8.0 6.6 5.5 3.8 5.1 5.2 3.5 8.2 7.2 3.0 8.0 8.2 9.6 67.9 7.1 7.1 6.5 2.1 6.7 5.7 6.4 11.1 7.0 15.2 3.2 6.0 2.9 4.1 13.4 3.3 5.0 2.7 3.6 4.9 14.2 7.0 0.6 3.7 4.1 7.6 6.2 7.8 3.2 12.9 5.2 13.9 8.6 13.0 2.4 7.8 12.8 6.6 18.7 2.5 17.7 8.2 2.8 11.0 13.2 8.8 4.6 6.7 7.2 12.8 2.7 12.1 9.0 20.1 9.8 11.1 4.1 15.0 7.5 5.6 2.7 7.2 10.0 3.9 6.2 11.9 3.6 10.0 3.3 4.0 5.9 20.0 5.5 7.0 5.7 11.8 7.9 0.0 2.1 4.5 4.6 1.8 2.7 2.8 2.8 2.9 2.7 4.1 4.1 3.0 0.9 1.3 2.3 1.8 0.9 2.4 6.4 7.6 6.0 7.3 5.4 4.9 8.1 12.3 8.0 8.0 7.1 11.1 3.0 0.0 8.1 23.8 7.2 0.9 1.8 5.3 13.1 3.5 4.3 3.7 2.2 1.5 10.1 3.7 4.2 3.0 8.1 4.8 1.9 2.7 187.5 40.8 3.6 3.5 4.2 6.5 17.0 4.3 1.7 2.8 16.8 4.5 5.7 4.8 2.9 6.4 2.7 3.3 25.4 4.5 6.1 7.6 2.0 213.1 4.1 6.7 0.0 38.4 5.5 2.6 7.2 21.1 42.9 3.2 2.2 3.0 3.4 2.8 5.7 2.9 62.6 4.0 0.0 2.2 3.5 28.8 8.9 5.0 2.3 2.9 8.6 2.9 4.7 2.0 ANKRA2 ENSG00000164331 "Ankyrin repeat family A member 2" Q9H9E1 5 73552190-73565667 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003968, HPA065263" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA003968: , HPA065263: AB_2685449" "unprognostic (1.75e-1)" "unprognostic (5.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-1)" "unprognostic (3.31e-1)" "unprognostic (3.89e-2)" "unprognostic (5.68e-2)" "unprognostic (6.19e-2)" "unprognostic (3.47e-2)" "unprognostic (1.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.79e-1)" "unprognostic (9.80e-3)" "unprognostic (3.36e-1)" "unprognostic (3.31e-1)" "unprognostic (6.65e-2)" "unprognostic (1.13e-3)" 7.8 11.3 4.6 5.7 5.1 14.0 10.1 5.7 5.4 9.4 5.2 8.9 9.6 12.4 13.1 7.5 11.4 9.7 8.2 4.2 5.1 5.9 10.8 7.0 9.9 5.0 4.9 14.1 8.3 8.0 7.5 10.0 5.3 12.4 10.4 9.9 10.9 8.4 7.6 9.1 9.6 8.3 5.1 8.8 10.0 6.7 5.2 10.0 14.3 6.6 8.1 7.4 7.7 6.2 6.6 4.5 6.6 7.5 12.3 19.3 20.6 9.0 13.2 7.6 11.0 1.4 9.4 6.2 7.0 8.8 7.3 4.5 3.1 15.4 10.9 11.9 5.5 5.4 3.6 6.5 9.6 3.1 9.3 19.8 21.0 9.1 9.2 13.6 8.7 6.7 5.3 9.9 8.6 3.8 5.6 8.5 3.9 2.5 3.7 3.5 7.1 8.7 5.6 8.2 9.0 6.9 6.9 5.3 11.0 10.2 8.2 5.0 11.2 3.0 3.4 4.9 6.3 19.7 15.1 5.3 7.5 5.1 8.8 19.9 5.1 11.2 7.6 4.5 9.3 9.9 8.9 10.7 4.6 8.0 13.3 12.4 8.4 7.3 7.8 5.3 11.5 6.8 4.6 5.1 5.7 5.4 4.2 5.1 5.0 4.9 5.3 5.1 5.2 6.2 10.7 3.2 11.5 10.4 23.5 15.8 30.1 29.8 26.2 26.2 20.7 15.9 8.9 31.5 22.7 18.4 10.4 26.3 27.1 16.0 27.4 14.1 1.3 18.1 11.0 12.8 24.1 21.5 10.0 16.6 22.2 13.8 10.7 13.4 19.0 18.8 15.7 23.8 10.5 23.5 12.9 22.6 36.7 18.5 6.7 2.2 32.6 11.1 12.4 16.9 15.1 16.2 17.5 21.1 22.3 16.9 20.0 29.0 14.6 25.7 21.5 18.0 21.4 21.2 26.3 11.3 17.8 25.6 15.9 16.0 12.4 48.8 20.4 16.3 17.0 36.8 ANKRD18A "FLJ35740, KIAA2015" ENSG00000180071 "Ankyrin repeat domain 18A" Q8IVF6 9 38571358-38620596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 18.2;brain: 21.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.3;Excitatory neurons: 24.8;Inhibitory neurons: 26.8;Oligodendrocytes: 118.1;Rod photoreceptor cells: 31.2;Spermatocytes: 53.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 17.9" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-3)" "unprognostic (1.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (4.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-2)" "unprognostic (1.94e-5)" "unprognostic (2.31e-2)" "unprognostic (1.63e-2)" "unprognostic (1.58e-2)" "unprognostic (7.03e-2)" "unprognostic (2.14e-1)" 0.0 0.1 3.0 0.3 9.1 18.2 0.4 3.6 3.7 0.4 0.0 0.5 0.3 0.2 0.2 0.8 0.5 0.4 0.6 3.1 5.1 0.9 0.7 0.3 0.2 12.6 6.0 0.0 2.2 0.6 1.0 0.1 14.3 0.9 0.7 5.0 0.4 0.1 0.0 1.3 0.7 0.2 5.1 0.1 1.0 7.2 8.4 0.3 2.2 0.0 0.1 0.2 0.4 21.9 4.8 3.7 3.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.9 0.0 0.0 0.9 3.5 3.4 0.0 0.0 5.2 0.0 5.6 2.9 0.0 17.9 0.5 0.0 2.3 0.0 3.1 1.7 0.0 7.2 1.7 0.4 0.3 4.6 0.1 0.9 3.7 6.2 2.1 0.0 6.5 6.8 2.1 2.0 1.5 3.0 2.4 0.5 0.2 7.1 2.6 8.3 4.5 0.0 1.3 0.1 0.0 0.3 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.0 9.1 3.6 3.7 3.1 5.1 12.6 6.0 14.3 5.1 8.4 21.9 0.1 0.0 1.5 1.0 0.1 0.6 2.0 1.5 3.4 3.8 2.3 2.4 9.4 1.5 3.7 1.8 2.1 0.0 0.1 0.8 1.9 5.4 8.0 33.3 1.7 0.2 4.2 0.0 24.8 2.4 0.9 0.2 7.7 19.2 0.0 14.7 0.0 0.5 0.1 0.0 26.8 3.3 2.0 0.0 0.3 2.2 0.6 0.2 0.0 1.0 0.4 9.2 0.0 18.1 118.1 3.9 2.6 0.4 0.1 1.9 1.6 0.3 11.0 31.2 0.0 0.0 0.3 53.5 4.3 3.8 1.7 0.0 1.4 0.3 2.3 1.4 ANKRD18B bA255A11.3 ENSG00000230453 "Ankyrin repeat domain 18B" A2A2Z9 9 33524394-33573009 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 34.5;choroid plexus: 10.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.4;Excitatory neurons: 13.8;Muller glia cells: 22.3;Spermatocytes: 41.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 27.5" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.71e-2)" "unprognostic (1.85e-1)" "unprognostic (4.85e-3)" "unprognostic (1.00e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.29e-4)" "unprognostic (1.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.65e-2)" "unprognostic (2.54e-4)" "unprognostic (1.01e-2)" "unprognostic (6.43e-5)" "unprognostic (4.89e-2)" "unprognostic (9.75e-4)" "unprognostic (8.25e-2)" "unprognostic (5.18e-2)" 0.4 0.2 16.8 0.0 17.5 0.1 0.1 34.5 30.1 0.2 10.6 0.0 0.0 0.1 0.1 1.9 0.2 0.4 0.0 18.2 13.6 0.0 0.0 0.1 0.1 22.3 15.7 0.0 0.0 0.0 0.4 0.2 21.4 1.2 0.0 1.9 0.1 0.0 0.7 2.2 0.0 0.0 12.7 0.3 0.0 3.9 14.5 0.0 0.2 0.1 0.1 0.7 0.9 17.0 10.0 8.8 0.6 0.1 0.2 1.5 0.9 2.1 2.1 2.7 2.9 2.1 0.2 0.2 0.4 0.3 2.9 2.2 5.9 2.1 3.6 0.1 5.2 10.2 13.1 1.5 0.0 3.5 0.6 0.8 3.6 3.7 9.3 0.7 5.0 0.0 5.5 0.5 3.0 1.7 0.0 27.5 9.1 0.2 4.8 0.0 13.0 2.0 1.6 2.4 0.3 8.5 4.2 0.3 0.4 5.5 7.5 13.4 4.6 1.5 5.8 4.4 3.9 1.5 0.8 0.0 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 17.5 34.5 30.1 18.2 13.6 22.3 15.7 21.4 12.7 14.5 17.0 0.0 0.0 0.0 0.7 0.0 2.0 5.4 2.9 1.2 8.5 0.5 0.9 3.1 4.3 2.8 1.8 0.0 0.0 0.0 0.6 0.0 0.8 34.4 12.1 0.2 0.3 0.0 0.0 13.8 0.5 0.4 0.1 0.0 4.0 0.0 12.1 0.4 0.1 0.2 0.0 9.0 2.0 4.1 0.0 0.3 3.7 0.6 0.2 0.0 1.9 0.0 22.3 0.0 4.0 0.8 0.4 1.7 0.7 0.0 2.5 0.3 0.1 9.8 5.5 0.0 0.5 0.5 41.4 2.1 6.2 3.3 0.0 0.2 0.0 1.3 3.9 ANKRD20A1 "ANKRD20A, DKFZp434A171" ENSG00000260691 "Ankyrin repeat domain 20 family member A1" Q5TYW2 9 67832765-67920552 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.3;testis: 4.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.8;Excitatory neurons: 14.8;Inhibitory neurons: 9.0;Oligodendrocyte precursor cells: 12.5;Spermatocytes: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 8.7;U-266/70: 8.7;U-266/84: 5.6" "HPA043239, HPA046346, HPA046695, HPA047112, HPA047167, HPA047766, HPA049923, HPA051288, HPA051753" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" Cytosol "HPA043239: , HPA046346: AB_2679631, HPA046695: , HPA047112: , HPA047167: , HPA047766: , HPA049923: AB_2680954, HPA051288: AB_2681421, HPA051753: AB_2681592" "unprognostic (4.92e-1)" "unprognostic (4.31e-3)" "unprognostic (3.97e-1)" "unprognostic (2.30e-2)" "unprognostic (5.94e-2)" "unprognostic (2.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-2)" "unprognostic (7.17e-2)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" 0.4 0.2 0.8 0.1 2.6 0.5 0.4 0.1 3.3 0.3 0.0 0.4 0.1 0.2 0.3 0.8 0.4 0.2 0.9 1.3 0.2 0.3 0.2 0.5 0.1 0.4 0.1 0.2 1.0 0.2 0.7 0.0 0.7 0.4 0.7 0.8 0.4 0.2 0.1 0.4 0.3 0.2 0.1 0.7 0.1 4.4 0.4 0.3 0.4 0.0 0.0 0.1 0.4 2.9 0.2 0.2 1.3 0.5 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 1.4 0.0 0.0 0.3 0.5 0.9 0.3 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.3 8.7 0.0 0.0 0.8 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.6 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.3 0.4 0.8 8.7 5.6 0.0 0.3 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 2.6 0.1 3.3 1.3 0.2 0.4 0.1 0.7 0.1 0.4 2.9 0.0 3.2 2.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.3 1.2 0.2 0.0 0.8 0.0 0.0 14.8 1.8 0.0 0.3 1.5 0.1 1.3 0.5 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.6 0.0 0.0 12.5 0.3 0.5 2.5 0.0 0.0 0.0 1.8 0.0 2.2 0.0 0.0 0.0 0.2 10.3 1.9 0.7 0.0 0.0 0.4 0.0 1.3 0.1 ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "skeletal muscle: 1438.6;tongue: 448.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 5.0;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 5.2;Skeletal myocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Karpas-707: 38.5" "Low region specificity" "Detected in many" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: AB_10673347" "unprognostic (2.48e-1)" "unprognostic (7.83e-4)" "unprognostic (4.93e-4)" "unprognostic (1.21e-2)" "unprognostic (4.28e-1)" "unprognostic (3.28e-1)" "unprognostic (3.27e-2)" "unprognostic (6.66e-2)" "unprognostic (2.46e-2)" "unprognostic (3.59e-2)" "unprognostic (1.81e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-6)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.70e-4)" 0.8 0.9 1.6 0.4 2.1 0.7 1.2 2.2 2.1 1.4 0.6 1.3 0.8 1.8 0.0 6.0 2.5 0.2 24.2 1.5 1.4 0.7 2.2 1.0 0.6 2.5 1.6 1.7 1.6 0.3 10.4 0.2 1.8 5.3 0.1 0.1 18.5 0.3 1438.6 2.5 1.3 0.2 1.5 2.3 0.7 0.7 1.9 0.6 1.1 448.6 0.4 1.2 1.1 2.3 0.5 0.7 0.4 0.8 0.0 0.2 1.1 0.3 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.3 0.3 0.2 1.1 1.0 0.5 0.8 0.2 0.1 0.8 1.8 0.3 0.3 0.6 0.0 0.2 0.1 1.5 0.9 38.5 0.3 0.9 0.5 0.8 0.4 0.1 0.3 1.4 0.0 5.0 0.2 0.9 1.4 0.2 0.3 0.7 0.0 0.2 1.1 0.0 0.3 0.5 0.6 0.7 0.1 1.7 0.7 0.3 0.4 1.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 2.1 2.2 2.1 1.5 1.4 2.5 1.6 1.8 1.5 1.9 2.3 1.1 0.0 1.1 2.0 0.5 0.8 0.5 0.4 0.6 2.6 0.8 2.3 5.0 0.0 1.5 0.0 2.1 0.4 2.1 0.9 0.0 0.3 3.3 1.3 1.9 0.8 0.0 0.4 2.8 1.1 0.2 1.3 0.5 0.7 1.3 1.1 1.4 1.2 0.2 1.7 2.7 1.0 0.0 0.6 0.3 1.8 1.5 0.6 0.0 1.0 0.2 1.1 1.0 0.5 2.9 0.1 0.3 3.0 0.4 0.3 0.6 0.2 7.4 5.2 0.0 6.1 1.6 1.3 0.4 0.4 1.3 0.3 1.1 0.7 0.9 0.2 ANKRD31 FLJ40191 ENSG00000145700 "Ankyrin repeat domain 31" Q8N7Z5 5 75068275-75236911 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.9" "Group enriched" "Detected in some" 7 "Spermatocytes: 148.9;Spermatogonia: 37.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA038028, HPA057566" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome NA NA "Cluster 35: T-regs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Centrosome" "Nucleoli, Vesicles" "HPA038028: AB_10672615, HPA057566: AB_2683470" "unprognostic (1.37e-1)" "unprognostic (4.28e-2)" "unprognostic (5.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.72e-2)" "unprognostic (4.81e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-2)" "unprognostic (1.69e-1)" "unprognostic (3.00e-2)" "unprognostic (4.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 4.9 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.1 0.1 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.5 5.2 0.4 0.4 0.4 0.5 0.6 3.3 0.8 1.1 1.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.3 3.6 2.8 0.8 0.1 0.0 0.8 5.8 0.2 0.6 0.4 4.1 0.4 12.0 0.5 0.4 0.0 0.1 1.7 5.4 0.0 0.0 0.0 0.0 4.7 1.5 0.1 0.0 1.0 0.1 1.3 0.0 3.0 5.6 0.1 0.1 0.4 1.3 0.0 0.1 0.3 1.2 2.2 13.1 0.6 0.4 148.9 37.7 0.4 0.1 0.3 1.1 0.7 0.1 0.2 ANKRD34B DP58 ENSG00000189127 "Ankyrin repeat domain 34B" A5PLL1 5 80556755-80570280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "brain: 40.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.0;Collecting duct cells: 3.7;Enteroendocrine cells: 1.8;Inhibitory neurons: 6.0;Kupffer cells: 1.2" "Cancer enhanced" "Detected in some" "prostate cancer: 2.3" "Region enhanced" "Detected in many" "thalamus: 40.7" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Cell line enriched" "Detected in some" 29 "RPTEC TERT1: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043327 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitochondria" Cytosol "HPA043327: AB_10794180" "unprognostic (1.05e-1)" "unprognostic (4.16e-6)" "unprognostic (2.07e-4)" "unprognostic (1.05e-1)" "unprognostic (3.03e-1)" "unprognostic (8.25e-4)" "unprognostic (6.44e-2)" "unprognostic (1.80e-1)" "unprognostic (9.41e-2)" "unprognostic (6.52e-3)" "unprognostic (1.93e-1)" "unprognostic (4.28e-2)" "unprognostic (1.02e-1)" "unprognostic (2.33e-1)" "unprognostic (2.94e-2)" 0.0 0.0 2.8 0.4 15.8 1.7 0.0 3.4 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 7.4 0.7 0.0 0.1 0.9 4.0 2.4 0.0 0.0 0.1 0.1 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 0.2 40.7 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 1.2 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 97.9 0.1 0.3 0.4 0.0 0.3 0.0 0.1 3.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.1 2.8 15.8 3.4 3.6 1.1 7.4 4.0 2.4 2.0 1.6 40.7 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 2.0 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.8 0.0 0.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 6.0 0.0 0.0 1.2 0.0 0.7 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ANKRD37 Lrp2bp ENSG00000186352 "Ankyrin repeat domain 37" Q7Z713 4 185396021-185400628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 93.7" "Cell type enhanced" "Detected in all" "Club cells: 257.6;Endometrial ciliated cells: 271.9;Respiratory ciliated cells: 263.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036626, HPA058127" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" Mitochondria "HPA036626: AB_10671963, HPA058127: AB_2683614" "unprognostic (9.08e-2)" "unprognostic (2.85e-3)" "unprognostic (3.89e-2)" "unprognostic (2.36e-3)" "unprognostic (1.19e-1)" "unprognostic (2.27e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (1.74e-1)" "unprognostic (1.09e-1)" "unprognostic (7.36e-2)" "unprognostic (9.69e-3)" "unprognostic (2.81e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "unprognostic (6.45e-3)" "unprognostic (1.08e-1)" 16.9 10.3 30.7 4.3 31.7 3.3 13.4 32.2 58.7 36.6 45.2 11.2 7.8 6.1 3.7 69.5 11.7 6.7 27.4 31.5 31.9 14.3 26.2 9.9 4.1 33.7 32.9 29.1 17.5 1.4 21.8 15.1 32.1 35.2 9.5 93.7 31.2 5.7 30.2 14.9 6.4 4.4 33.9 7.1 9.0 11.2 34.7 5.1 23.9 13.3 7.5 10.8 29.6 32.4 12.6 1.6 1.1 5.4 7.4 4.5 4.9 4.8 3.7 3.7 6.8 2.9 3.4 4.3 2.4 8.4 6.4 4.3 6.5 6.2 4.2 12.4 0.7 2.8 5.8 8.3 3.3 2.4 7.6 1.2 6.4 3.0 3.6 23.8 3.9 2.9 5.0 8.2 9.4 2.6 2.6 12.1 1.7 1.1 8.3 0.5 1.5 13.4 4.5 1.1 7.2 12.9 3.7 4.1 14.4 4.6 4.1 2.3 5.1 6.6 5.0 4.2 5.1 13.3 5.2 2.2 20.9 2.8 6.9 0.5 3.3 8.3 4.1 3.2 3.9 6.8 3.6 6.7 2.0 6.9 2.4 3.4 1.2 3.9 3.3 3.4 4.5 2.5 30.7 31.7 32.2 58.7 31.5 31.9 33.7 32.9 32.1 33.9 34.7 32.4 39.3 22.4 28.7 9.1 104.2 59.4 41.8 197.9 42.7 29.9 66.9 92.3 1.8 11.5 257.6 9.2 29.2 25.0 69.8 93.8 25.4 25.2 6.2 271.9 18.9 44.7 119.9 8.4 8.0 23.3 43.0 28.6 142.2 96.5 61.7 7.7 12.1 25.8 15.4 10.1 7.9 186.6 89.5 8.1 170.2 3.2 9.3 53.3 142.3 12.2 17.7 99.8 1.0 4.0 4.6 32.3 53.3 11.7 223.5 38.5 60.9 31.5 263.3 115.2 6.6 27.3 38.7 32.1 28.4 54.0 48.2 84.4 65.8 7.4 50.8 20.2 ANKRD40 MGC15396 ENSG00000154945 "Ankyrin repeat domain 40" Q6AI12 17 50693198-50707914 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021668, HPA021759, HPA074884" Uncertain Approved "Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center, Cytosol" "HPA021668: AB_1844843, HPA021759: AB_2227411, HPA074884: " "unprognostic (2.73e-1)" "unprognostic (1.82e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (4.99e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (7.02e-4)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (3.84e-2)" "unprognostic (1.53e-1)" "unprognostic (4.77e-2)" "unprognostic (1.00e-2)" "unprognostic (9.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.32e-1)" 42.8 19.7 126.7 15.5 163.3 7.8 25.7 130.4 159.3 20.6 63.4 32.0 11.8 23.8 13.7 18.4 19.4 16.2 27.6 98.5 115.4 17.8 17.8 22.5 16.6 150.3 152.4 20.6 19.4 26.9 10.8 23.1 142.2 18.3 16.3 20.7 15.0 24.7 107.0 14.4 16.3 27.9 141.3 20.5 18.7 10.3 135.2 16.9 16.9 84.0 14.4 25.3 16.9 164.8 41.1 38.6 34.2 34.6 48.2 39.8 29.9 36.2 39.5 41.3 38.7 82.6 20.5 43.3 49.2 46.4 44.3 22.8 49.3 29.4 66.8 40.0 31.7 59.1 25.1 40.7 26.4 41.6 24.0 34.3 29.5 40.3 50.1 30.2 32.9 35.1 34.0 42.3 34.4 32.0 52.2 15.1 38.0 33.0 36.1 35.2 61.9 30.8 32.5 34.8 18.1 50.5 20.2 27.2 39.6 59.1 31.4 27.4 40.4 55.8 44.1 29.2 46.7 44.3 43.4 38.3 30.6 15.9 46.4 7.4 7.0 3.1 10.9 11.2 12.5 9.8 12.0 12.3 7.1 9.2 11.1 13.4 1.8 10.7 12.3 14.2 9.3 4.6 126.7 163.3 130.4 159.3 98.5 115.4 150.3 152.4 142.2 141.3 135.2 164.8 39.0 16.0 11.4 11.4 13.9 45.0 24.2 6.1 11.4 14.3 19.8 11.7 31.7 12.8 4.9 18.4 4.2 14.9 19.9 13.5 27.4 16.6 1.8 10.4 20.3 31.4 6.0 7.4 16.0 17.5 18.9 19.6 5.6 16.1 9.5 14.3 32.9 21.9 19.0 35.3 15.6 12.3 6.1 32.4 25.1 3.1 34.2 16.3 26.6 11.2 13.2 19.6 8.2 12.1 32.2 19.9 8.4 37.6 4.5 30.5 9.6 24.8 5.0 12.0 46.0 39.1 27.3 17.5 21.1 10.4 33.2 10.7 15.7 9.7 12.8 24.1 ANKRD42 "FLJ37874, PPP1R79, SARP" ENSG00000137494 "Ankyrin repeat domain 42" Q8N9B4 11 83193712-83260694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 37.2" "Cell type enhanced" "Detected in all" "Early spermatids: 170.5;Late spermatids: 63.2;Respiratory ciliated cells: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039917 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039917: AB_10672894" "unprognostic (6.59e-2)" "unprognostic (9.00e-2)" "unprognostic (1.00e-1)" "unprognostic (1.31e-3)" "unprognostic (9.12e-2)" "unprognostic (3.78e-1)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" "unprognostic (2.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.09e-2)" "unprognostic (3.10e-3)" "unprognostic (1.79e-1)" "unprognostic (4.25e-1)" "unprognostic (1.90e-1)" 5.2 13.3 8.0 5.2 8.9 9.0 6.0 4.3 11.8 7.4 15.8 5.8 5.2 6.0 19.7 4.8 15.8 7.6 5.3 11.6 14.3 11.1 4.7 6.6 3.8 10.0 9.2 8.7 5.9 12.3 13.1 3.9 7.9 7.2 4.2 17.8 6.0 7.4 2.7 5.5 4.9 5.3 7.6 4.5 6.2 37.2 10.7 2.8 11.8 2.2 4.1 7.3 5.5 8.2 5.6 9.7 4.7 9.5 14.3 15.0 4.1 11.4 8.8 6.7 4.1 5.9 6.8 2.2 14.1 10.3 13.4 11.9 5.0 7.8 5.5 3.2 3.7 4.0 14.5 4.0 10.0 11.6 9.0 8.9 8.8 17.0 8.9 12.3 7.0 4.0 12.0 2.0 9.8 7.9 1.7 12.2 3.9 8.8 6.1 2.7 6.5 2.8 21.8 6.6 3.7 4.9 14.9 9.2 2.9 6.1 13.9 6.2 10.2 10.2 7.1 37.1 5.4 2.9 7.1 4.5 7.9 6.7 4.3 5.7 2.6 3.2 2.9 3.0 1.9 5.0 2.5 2.9 3.5 3.8 1.2 2.0 2.0 4.4 8.0 1.4 1.1 1.7 8.0 8.9 4.3 11.8 11.6 14.3 10.0 9.2 7.9 7.6 10.7 8.2 7.6 9.6 16.0 7.5 8.5 11.2 21.5 6.5 4.0 3.9 11.9 9.8 7.8 8.6 8.0 7.3 39.6 3.1 7.1 5.2 9.8 7.7 170.5 53.1 21.9 8.5 3.0 2.1 33.3 6.7 3.3 13.0 7.7 15.4 13.9 7.8 9.3 4.8 5.0 1.7 27.3 3.1 12.2 7.2 9.9 63.2 8.7 8.8 7.2 7.5 7.3 7.4 2.1 4.5 2.9 5.7 4.9 10.5 4.7 10.6 5.8 14.8 61.6 22.4 13.1 16.6 9.0 55.5 17.3 4.7 15.3 5.5 9.1 14.5 3.9 11.5 ANKRD45 "CT117, FLJ45235" ENSG00000183831 "Ankyrin repeat domain 45" Q5TZF3 1 173608336-173669851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 6.7;choroid plexus: 14.3;fallopian tube: 12.7;parathyroid gland: 9.3;testis: 11.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Early spermatids: 48.8;Endometrial ciliated cells: 23.7;Late spermatids: 16.8;Respiratory ciliated cells: 31.8;Spermatocytes: 54.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.5;BJ hTERT+: 2.0;BJ hTERT+ SV40 Large T+ RasG12V: 2.6;GAMG: 1.9;HBF TERT88: 1.9;SH-SY5Y: 5.7" "HPA031655, HPA031656, HPA031657" Enhanced Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane, Centrosome" "HPA031655: AB_10610975, HPA031656: AB_10600331, HPA031657: AB_10602196" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-1)" "unprognostic (3.57e-2)" "unprognostic (2.69e-3)" "unprognostic (4.15e-2)" "unprognostic (6.93e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (4.49e-2)" "unprognostic (8.80e-3)" "unprognostic (2.91e-2)" "unprognostic (5.15e-2)" "unprognostic (1.61e-1)" 0.2 0.6 2.8 0.0 5.4 0.2 0.1 1.9 2.5 1.3 14.3 0.2 0.0 1.6 0.7 0.0 12.7 0.3 0.4 4.3 2.8 1.3 0.0 1.2 0.0 5.2 6.7 0.7 0.3 9.3 1.8 0.0 3.9 0.8 0.1 2.6 0.0 0.3 0.2 0.0 0.0 1.1 3.3 0.4 0.1 11.0 3.8 0.2 0.5 0.0 0.0 0.1 0.1 4.0 0.0 0.0 5.5 0.0 0.0 0.3 0.1 0.0 2.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 5.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 5.4 1.9 2.5 4.3 2.8 5.2 6.7 3.9 3.3 3.8 4.0 0.2 0.0 1.7 12.4 0.0 0.3 0.3 1.1 0.0 0.7 0.1 0.4 0.9 0.0 1.5 5.5 37.5 0.2 0.0 0.3 1.9 0.6 48.8 23.7 1.3 1.3 0.0 0.0 4.6 0.5 0.3 0.4 0.0 0.6 0.0 1.1 3.3 0.0 0.1 0.0 4.1 0.0 6.1 0.0 0.0 16.8 1.8 0.2 0.0 2.8 0.0 3.3 0.0 0.5 3.2 0.1 0.0 0.4 0.0 0.2 0.0 0.4 31.8 1.7 0.0 0.1 0.8 54.9 7.9 0.0 0.0 0.1 0.0 5.5 0.4 0.1 ANKRD49 "FGIF, FLJ20189, GBIF" ENSG00000168876 "Ankyrin repeat domain 49" Q8WVL7 11 94493979-94499578 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040273, HPA048137" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA040273: AB_10674991, HPA048137: AB_2680279" "unprognostic (1.52e-2)" "unprognostic (2.76e-2)" "unprognostic (1.92e-1)" "unprognostic (5.22e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-3)" "unprognostic (1.46e-2)" "unprognostic (7.21e-3)" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (4.21e-3)" "prognostic unfavorable (9.96e-4)" "unprognostic (6.32e-3)" "unprognostic (2.82e-1)" "unprognostic (3.40e-2)" "prognostic favorable (6.16e-4)" 7.8 6.8 8.3 12.7 8.9 25.2 13.1 11.1 11.4 9.7 8.2 10.8 11.4 10.4 18.3 9.5 8.5 8.4 5.3 8.3 8.4 7.8 8.6 7.5 20.8 8.2 7.7 12.6 13.4 9.3 8.9 12.1 8.0 10.9 13.6 11.8 10.7 10.8 5.8 10.2 16.2 8.8 7.8 15.6 12.7 5.4 9.3 17.1 14.2 7.3 20.8 7.9 8.5 9.5 8.9 4.4 11.0 9.4 10.2 12.0 13.5 13.3 12.0 14.9 17.1 20.7 18.4 23.4 20.9 8.5 12.5 20.5 14.0 9.8 12.2 17.9 12.1 18.9 16.8 7.8 11.1 17.8 15.8 9.1 23.1 10.7 14.9 10.4 11.3 20.9 18.4 14.4 9.4 6.1 19.8 32.8 6.3 17.5 9.8 14.9 11.3 12.0 12.9 9.2 10.5 10.9 10.2 9.8 8.7 18.4 18.0 12.9 7.5 13.0 9.3 13.8 7.2 7.6 20.0 24.6 4.4 21.8 7.4 77.8 23.1 23.9 21.9 19.5 23.7 34.1 23.4 19.4 18.4 28.8 28.4 25.9 42.7 27.2 15.8 30.5 31.4 17.8 8.3 8.9 11.1 11.4 8.3 8.4 8.2 7.7 8.0 7.8 9.3 9.5 20.5 12.8 9.3 11.1 43.2 5.6 10.0 15.1 14.2 16.3 14.0 11.3 9.1 24.3 15.4 25.8 14.6 31.1 36.1 27.8 21.5 20.3 10.1 11.9 18.1 15.4 13.3 40.0 11.1 23.0 13.8 16.5 27.0 15.1 21.5 18.7 16.4 18.8 14.3 11.8 9.5 23.6 8.2 28.5 8.4 3.7 35.8 18.5 10.6 8.4 28.1 21.8 57.7 5.5 12.7 22.8 35.2 23.7 28.0 11.3 45.3 19.3 8.1 14.4 26.3 11.3 18.4 21.0 19.9 11.6 6.8 28.0 36.5 9.8 22.0 5.8 ANKRD54 LIAR ENSG00000100124 "Ankyrin repeat domain 54" Q6NXT1 22 37830855-37849327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071287 Approved Approved Nucleoplasm,Microtubules,Midbody Yes No "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Midbody" Nucleoplasm "HPA071287: AB_2686380" "unprognostic (5.36e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.02e-1)" "prognostic favorable (7.38e-5)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.41e-2)" "prognostic favorable (6.16e-4)" "unprognostic (2.53e-1)" "unprognostic (6.33e-2)" "unprognostic (1.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-3)" 8.6 18.7 22.4 5.9 20.8 6.9 9.1 22.6 23.3 13.0 28.7 16.4 7.1 12.9 7.8 14.0 23.8 6.3 12.4 23.0 26.2 14.9 15.6 8.4 6.4 22.6 24.7 17.8 18.1 11.7 19.2 5.4 21.6 13.7 6.6 6.3 13.9 11.0 12.6 11.3 8.9 9.5 22.0 9.2 10.9 30.9 26.1 10.4 13.8 8.7 7.2 14.0 10.9 20.3 18.5 18.6 15.4 23.0 19.9 11.3 8.1 24.8 19.2 41.1 25.2 11.8 7.3 17.8 10.1 16.5 13.3 16.4 19.5 14.1 19.9 14.2 39.5 9.3 17.3 28.3 17.7 17.8 20.8 10.1 14.2 22.6 13.3 10.3 25.5 13.1 11.9 12.7 19.1 19.8 17.6 21.1 4.4 24.5 16.5 20.2 18.3 11.3 23.2 6.4 26.4 14.1 20.7 18.8 30.8 7.0 19.3 28.0 15.1 24.5 25.6 12.9 18.6 13.3 11.7 14.3 20.1 15.1 17.9 3.5 4.5 2.2 5.4 5.5 5.4 3.9 5.1 4.0 5.7 5.2 5.3 2.6 2.7 10.2 9.3 5.3 2.4 3.3 22.4 20.8 22.6 23.3 23.0 26.2 22.6 24.7 21.6 22.0 26.1 20.3 8.4 12.8 14.5 11.8 14.4 15.8 11.0 12.4 12.0 18.3 16.9 15.6 8.1 24.3 12.2 18.4 29.2 20.9 14.0 19.9 39.2 17.1 6.4 47.8 12.6 10.9 9.0 12.8 9.4 14.7 17.7 12.3 12.2 8.5 9.5 23.3 13.6 12.0 13.2 26.9 9.4 14.3 12.2 12.5 10.7 7.7 18.0 8.8 10.6 2.8 9.2 18.5 17.5 13.6 8.6 11.3 15.3 21.4 8.4 11.4 19.2 22.0 48.2 23.2 6.6 13.1 13.4 65.6 42.1 12.7 17.6 16.8 13.3 25.4 20.7 9.9 ANKRD55 FLJ11795 ENSG00000164512 "Ankyrin repeat domain 55" Q3KP44 5 56099680-56233330 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.3;liver: 3.1;lymphoid tissue: 3.6;testis: 9.8" "Cell type enhanced" "Detected in some" "Early spermatids: 161.3;Hepatic stellate cells: 41.7;Inhibitory neurons: 103.5;Late spermatids: 29.1;Spermatocytes: 59.3" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 22.9;eosinophil: 20.7;naive CD4 T-cell: 19.8" "Group enriched" "Detected in many" 74 "granulocytes: 22.9;T-cells: 19.8" "Group enriched" "Detected in some" 6 "HEL: 34.4;HMC-1: 17.1;NB-4: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051049, HPA061649" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear speckles" Cytosol "HPA051049: AB_2681326, HPA061649: " "unprognostic (1.00e-4)" "unprognostic (1.58e-4)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (7.78e-4)" "unprognostic (1.46e-3)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" "unprognostic (7.19e-6)" "unprognostic (2.56e-2)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (1.01e-1)" 0.4 0.1 2.2 0.7 3.0 0.7 0.1 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.3 0.1 0.9 8.3 0.4 3.1 0.3 3.6 4.1 4.6 0.1 0.0 0.0 0.2 0.6 5.2 0.0 0.2 0.4 1.0 0.0 0.0 0.4 1.3 0.1 3.3 1.6 0.3 9.8 7.8 3.2 0.2 0.0 2.0 0.3 0.1 0.9 0.2 0.3 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.2 1.3 0.0 1.6 17.1 0.0 0.1 0.0 0.0 0.1 4.2 0.1 2.9 1.1 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 1.7 0.0 2.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 2.0 0.4 22.9 0.2 20.7 0.1 0.1 0.0 0.0 4.3 0.0 0.1 0.0 19.8 0.8 2.0 0.0 0.1 0.0 1.0 2.8 2.2 3.0 0.0 2.4 0.9 8.3 4.1 4.6 5.2 3.3 7.8 0.9 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 1.5 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 161.3 0.4 0.8 2.2 0.0 0.0 1.3 0.2 0.3 0.6 0.5 7.5 2.5 0.1 41.7 0.6 0.7 0.0 103.5 0.0 0.0 3.2 1.9 29.1 0.6 1.4 1.8 1.0 0.9 0.9 3.1 18.6 1.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 59.3 0.6 0.0 0.0 1.2 3.9 0.5 0.0 0.2 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 ANKS1B "AIDA-1, ANKS2, cajalin-2, EB-1" ENSG00000185046 "Ankyrin repeat and sterile alpha motif domain containing 1B" Q7Z6G8 12 98726457-99984654 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 77.0;skeletal muscle: 34.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 2224.0;Inhibitory neurons: 1545.5;Oligodendrocyte precursor cells: 1318.0;Oligodendrocytes: 1000.1" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 10.3;ASC TERT1: 5.8;SCLC-21H: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078230 Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA078230: " "unprognostic (5.50e-2)" "unprognostic (3.26e-2)" "unprognostic (1.01e-2)" "unprognostic (6.87e-3)" "unprognostic (1.18e-1)" "unprognostic (1.14e-4)" "unprognostic (7.94e-2)" "unprognostic (2.47e-1)" "unprognostic (1.84e-2)" "unprognostic (3.03e-2)" "unprognostic (4.97e-4)" "unprognostic (2.81e-1)" "unprognostic (1.14e-3)" "unprognostic (1.64e-2)" "unprognostic (1.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.75e-3)" 1.6 3.6 36.2 0.7 50.4 0.1 2.7 40.2 77.0 2.9 0.0 4.0 0.5 2.3 1.4 2.9 3.6 1.2 1.4 51.8 5.2 4.6 1.1 1.0 0.6 0.0 7.9 8.9 1.1 0.8 10.1 1.8 2.0 3.1 1.0 6.2 3.1 2.7 34.2 1.0 1.1 2.3 0.4 1.1 1.4 7.6 13.8 1.0 5.6 1.8 0.3 2.1 1.7 71.6 0.2 2.2 10.3 2.4 4.0 5.8 0.5 0.0 1.1 0.7 0.8 0.2 0.7 0.8 0.4 1.5 3.1 0.4 0.1 0.0 0.2 1.2 0.7 0.1 0.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.7 0.1 0.6 0.4 0.5 2.9 0.0 1.9 0.7 0.0 0.2 0.1 0.0 11.1 1.1 0.9 3.2 1.2 0.8 3.7 0.1 0.1 0.9 0.9 0.6 0.6 0.0 0.7 0.5 0.9 0.2 0.9 3.7 0.6 1.1 0.7 1.0 1.1 0.9 1.3 0.7 0.6 0.9 1.0 1.0 1.9 1.5 1.6 1.2 4.3 0.6 36.2 50.4 40.2 77.0 51.8 5.2 0.0 7.9 2.0 0.4 13.8 71.6 0.5 3.2 3.9 228.8 0.8 1.1 1.1 0.2 4.6 32.9 6.3 2.4 2.4 0.0 1.3 9.2 18.8 0.4 0.5 0.0 0.0 0.5 142.2 2.6 0.8 0.8 0.0 0.0 2224.0 0.0 0.3 5.7 1.1 0.9 1.3 0.3 0.4 0.5 0.6 30.3 1545.5 0.0 0.0 0.0 1.9 92.0 1.2 0.4 5.4 84.3 0.2 1.7 1.0 1318.0 1000.1 0.0 1.1 6.0 0.3 0.5 0.0 5.0 3.1 3.4 6.6 12.1 1.8 31.8 3.9 2.6 1.4 0.8 2.1 0.5 0.1 0.6 ANKS6 "ANKRD14, FLJ36928, NPHP16, SAMD6" ENSG00000165138 "Ankyrin repeat and sterile alpha motif domain containing 6" Q68DC2 9 98731329-98796965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Inhibitory neurons: 48.6;Oligodendrocytes: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008355 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Nucleoplasm, Cytosol" "HPA008355: AB_2058277" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (9.31e-2)" "unprognostic (9.15e-3)" "unprognostic (6.90e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-3)" "unprognostic (4.10e-2)" "unprognostic (1.48e-1)" "unprognostic (3.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.94e-2)" "prognostic favorable (3.44e-5)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.68e-1)" 5.7 4.8 8.0 3.2 8.8 1.5 4.7 14.3 10.0 9.5 7.6 10.5 4.2 8.9 4.9 8.7 10.2 3.3 3.9 8.1 7.7 9.4 2.7 6.6 2.4 12.5 8.9 10.3 12.8 5.5 4.8 2.0 12.4 5.5 4.9 2.2 5.4 2.3 3.7 5.3 7.7 4.9 8.2 3.2 11.5 5.7 10.1 2.6 13.6 1.0 2.9 8.7 5.2 9.7 8.2 12.3 10.9 19.3 9.0 7.3 7.4 5.9 10.0 6.5 7.7 6.7 5.8 15.2 4.4 8.4 9.2 23.9 8.1 9.9 3.4 21.2 8.3 3.6 7.7 2.9 8.8 2.0 2.3 8.9 12.0 8.7 8.9 7.9 7.4 13.8 26.0 3.5 5.0 13.5 0.9 3.9 17.3 36.3 12.2 10.2 26.8 1.2 11.7 5.1 7.1 8.1 2.5 14.2 6.7 8.8 0.0 4.1 7.6 6.5 7.2 18.4 5.8 6.8 12.1 2.4 9.4 6.8 9.8 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 8.0 8.8 14.3 10.0 8.1 7.7 12.5 8.9 12.4 8.2 10.1 9.7 3.5 6.4 10.5 16.0 2.4 1.8 0.9 8.2 5.2 12.0 1.5 2.2 4.4 10.0 7.7 12.9 8.4 3.1 1.5 5.1 3.9 4.2 3.0 3.7 5.3 3.2 4.9 0.8 52.8 8.9 2.7 4.9 7.7 3.9 1.3 6.2 1.8 1.7 1.9 0.0 48.6 7.1 0.0 1.3 0.9 5.8 2.8 0.9 0.0 9.4 0.7 1.9 2.1 14.1 54.2 9.3 3.1 4.5 1.4 3.9 4.8 5.9 11.1 0.8 0.0 2.7 3.2 3.8 5.9 5.6 1.1 1.1 2.4 6.2 10.4 2.9 ANKZF1 "FLJ10415, Vms1, ZNF744" ENSG00000163516 "Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1" Q9H8Y5 2 219229783-219236679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035208 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035208: AB_10602229" "unprognostic (5.23e-2)" "unprognostic (2.23e-1)" "unprognostic (1.12e-3)" "unprognostic (8.27e-2)" "unprognostic (3.38e-1)" "unprognostic (7.95e-3)" "prognostic unfavorable (3.09e-5)" "unprognostic (3.87e-2)" "unprognostic (9.68e-3)" "unprognostic (7.82e-3)" "unprognostic (1.24e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (2.01e-6)" "unprognostic (1.49e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-1)" "unprognostic (2.88e-3)" 9.1 9.2 7.8 8.8 8.6 7.8 10.8 9.9 9.8 13.8 9.6 13.1 9.6 10.1 3.2 15.2 13.5 6.1 14.1 7.9 8.0 13.9 14.4 10.7 13.7 10.1 8.5 16.0 15.6 6.4 12.5 5.9 9.3 15.1 5.2 8.2 15.3 5.6 16.9 17.3 15.2 4.6 7.9 18.1 14.2 7.9 8.7 11.9 11.9 8.1 8.3 12.4 15.0 10.5 31.6 6.1 8.1 11.8 10.6 8.8 32.5 10.1 10.0 13.6 17.2 14.9 13.2 6.6 18.0 4.3 15.3 22.7 10.5 17.5 10.0 13.9 11.0 14.6 19.1 13.9 10.6 9.6 13.7 8.9 33.1 10.1 15.9 22.6 9.4 17.0 24.8 14.9 6.9 13.6 14.1 24.1 13.5 13.7 10.9 14.3 9.9 21.4 7.6 7.9 10.3 10.5 11.9 23.9 19.8 19.5 6.4 23.7 10.3 11.4 8.7 10.1 13.3 31.6 19.9 12.9 19.4 13.8 5.1 9.9 9.1 11.0 16.1 9.0 17.4 13.0 16.3 16.2 9.4 13.3 19.0 18.0 12.3 24.4 14.0 9.8 17.1 13.6 7.8 8.6 9.9 9.8 7.9 8.0 10.1 8.5 9.3 7.9 8.7 10.5 10.2 16.0 17.2 24.2 28.0 9.3 14.5 28.9 9.6 39.8 14.4 13.6 9.2 11.5 24.8 12.9 31.3 10.5 32.7 17.3 13.7 20.5 4.4 28.2 9.7 11.8 9.6 19.6 19.0 12.6 27.2 8.9 17.9 13.0 21.6 21.4 8.6 13.1 7.7 32.0 21.0 19.1 20.3 8.2 5.3 4.0 23.9 10.9 10.6 6.5 15.6 18.0 43.3 13.6 25.3 14.2 16.0 16.6 17.7 13.6 25.2 16.5 65.1 55.4 6.6 13.2 12.8 10.1 17.0 8.3 9.9 11.6 30.0 21.3 17.6 11.1 ANP32A "C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32" ENSG00000140350 "Acidic nuclear phosphoprotein 32 family member A" P39687 15 68778535-68820897 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005231, HPA063133, HPA067561" Supported Enhanced Nucleoplasm,Centrosome,Cytosol NA NA 770000 "Cluster 52: Eosinophils - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Centrosome" Cytosol "CAB005231: AB_2289588, HPA063133: AB_2684947, HPA067561: AB_2685861" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (3.03e-1)" "unprognostic (6.96e-2)" "unprognostic (2.29e-2)" "unprognostic (1.04e-2)" "unprognostic (4.44e-2)" "unprognostic (4.00e-2)" "unprognostic (3.74e-2)" "unprognostic (1.20e-1)" "unprognostic (7.83e-2)" "unprognostic (4.16e-2)" "unprognostic (3.24e-2)" "unprognostic (2.38e-2)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" 50.8 34.7 50.2 87.3 60.5 137.0 71.6 62.3 59.1 54.0 33.3 81.0 70.8 59.1 50.7 65.8 75.1 59.8 127.9 48.8 57.3 75.1 76.4 71.0 156.2 60.0 56.5 57.8 53.7 61.4 27.5 101.5 65.4 75.4 89.0 106.0 54.0 66.8 62.4 36.1 76.9 57.0 62.7 85.5 78.9 20.8 54.3 203.0 73.6 64.5 141.2 76.4 43.6 71.0 196.4 234.7 303.2 263.2 104.2 90.9 200.5 101.0 134.3 193.5 161.8 195.3 358.0 629.8 184.5 114.5 114.2 279.9 709.5 206.6 230.8 286.6 241.2 478.6 192.7 247.8 64.5 380.8 247.4 72.9 143.1 106.3 210.2 126.6 285.9 300.0 354.5 239.1 168.2 136.1 386.1 311.6 270.1 192.5 118.2 531.7 280.7 375.3 170.5 304.5 399.8 247.8 153.7 170.8 282.7 301.1 227.2 491.4 129.0 199.0 313.5 139.3 275.2 143.8 433.9 733.8 132.2 632.1 186.7 12.9 26.4 44.9 16.8 30.6 14.2 18.7 13.8 17.8 30.0 17.9 16.5 14.9 27.2 28.8 27.5 26.8 17.2 16.0 50.2 60.5 62.3 59.1 48.8 57.3 60.0 56.5 65.4 62.7 54.3 71.0 100.2 109.0 118.0 20.2 98.1 64.7 67.7 147.0 91.0 92.2 57.3 70.6 80.0 60.1 105.4 69.9 35.5 258.2 119.7 57.1 107.6 112.5 6.7 61.2 67.7 91.8 78.5 144.2 16.8 96.1 172.4 57.5 69.3 70.1 92.4 63.6 78.1 81.8 194.1 65.6 17.4 92.1 114.0 150.1 112.6 6.3 34.8 111.6 78.2 37.5 158.9 103.7 84.5 15.6 55.4 79.8 57.0 29.7 92.6 59.7 99.3 148.0 113.7 87.2 26.3 49.9 75.1 8.8 18.2 86.4 34.9 232.5 99.5 82.5 94.7 52.0 ANP32B "APRIL, PHAPI2, SSP29" ENSG00000136938 "Acidic nuclear phosphoprotein 32 family member B" Q92688 9 97983341-98015943 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063133, HPA067561, HPA069657" Supported Enhanced Nucleoplasm,Centrosome,Cytosol NA NA 570000 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "HPA063133: AB_2684947, HPA067561: AB_2685861, HPA069657: " "unprognostic (2.82e-1)" "unprognostic (2.05e-2)" "unprognostic (4.57e-2)" "unprognostic (6.74e-2)" "unprognostic (1.85e-1)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.98e-7)" "unprognostic (6.76e-3)" "unprognostic (5.70e-2)" "unprognostic (7.16e-2)" "unprognostic (3.50e-1)" "unprognostic (6.39e-2)" "unprognostic (9.22e-3)" "unprognostic (5.20e-2)" "unprognostic (2.36e-1)" "unprognostic (3.67e-2)" "unprognostic (1.78e-2)" 144.0 77.1 134.8 124.0 155.9 365.7 138.6 134.0 187.6 161.6 112.0 145.5 95.1 116.2 104.7 140.9 127.2 60.4 92.3 113.7 150.0 100.2 103.5 122.4 222.6 171.4 149.8 168.5 156.4 68.7 68.1 110.5 158.5 98.6 118.7 46.2 110.6 71.4 109.6 148.0 127.3 78.0 155.6 123.8 131.9 59.6 142.6 271.5 96.9 50.6 248.4 132.5 146.6 173.4 659.7 347.4 378.6 318.4 208.1 365.2 344.4 332.6 292.4 349.2 291.9 438.3 313.1 798.2 194.2 224.6 266.3 423.9 516.1 375.2 397.1 523.0 290.9 692.4 289.1 478.4 266.9 1201.9 386.8 278.7 268.8 280.9 574.0 283.2 307.9 701.5 1359.2 548.8 272.6 875.7 913.5 1062.0 148.2 638.8 341.2 537.8 589.5 381.7 228.8 269.9 304.2 265.8 390.4 376.2 364.5 185.3 213.2 444.0 377.0 226.5 367.3 288.3 355.5 493.2 601.3 469.1 209.7 472.7 432.1 91.3 83.6 118.8 65.2 95.5 89.3 106.1 122.5 92.8 100.5 93.0 143.8 112.1 34.2 74.1 149.7 96.4 162.5 85.3 134.8 155.9 134.0 187.6 113.7 150.0 171.4 149.8 158.5 155.6 142.6 173.4 127.9 86.6 101.8 7.8 227.7 180.7 201.3 180.0 208.9 61.1 100.4 126.0 85.8 112.9 120.7 75.4 25.0 345.5 159.5 159.1 97.8 144.9 114.9 73.8 176.3 146.9 149.9 709.4 5.8 171.6 537.9 121.9 123.3 117.5 119.7 247.9 159.5 96.6 284.7 119.5 6.2 242.2 75.3 310.6 152.0 95.2 146.3 222.5 128.1 14.0 263.5 68.9 149.3 8.0 18.8 137.1 151.1 145.2 266.5 260.6 177.7 101.9 56.3 42.1 151.2 113.4 189.4 204.3 339.0 243.0 154.1 333.1 217.6 188.9 302.7 234.1 ANP32D PP32R2 ENSG00000139223 "Acidic nuclear phosphoprotein 32 family member D" O95626 12 48472559-48473622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Smooth muscle cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063133, HPA067561" Uncertain Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Centrosome" Cytosol "HPA063133: AB_2684947, HPA067561: AB_2685861" "unprognostic (2.20e-1)" "unprognostic (3.75e-1)" "unprognostic (3.18e-1)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (1.72e-3)" "unprognostic (2.30e-2)" "unprognostic (3.62e-3)" "unprognostic (2.76e-2)" "unprognostic (3.48e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 ANP32E "LANP-L, LANPL, MGC5350" ENSG00000143401 "Acidic nuclear phosphoprotein 32 family member E" Q9BTT0 1 150218417-150236156 "Predicted intracellular proteins" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB021114, HPA063133, HPA067561" Supported Enhanced Nucleoplasm,Centrosome,Cytosol NA NA 280000 "Cluster 44: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" Cytosol "CAB021114: AB_10057407, HPA063133: AB_2684947, HPA067561: AB_2685861" "unprognostic (1.04e-1)" "unprognostic (2.40e-1)" "unprognostic (2.51e-1)" "unprognostic (8.95e-2)" "unprognostic (1.69e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (4.50e-5)" "unprognostic (1.64e-1)" "unprognostic (6.58e-2)" "unprognostic (3.91e-2)" "unprognostic (7.73e-3)" "unprognostic (2.47e-1)" "prognostic unfavorable (3.82e-8)" "unprognostic (1.76e-2)" "unprognostic (1.60e-1)" "unprognostic (1.77e-1)" "unprognostic (3.52e-1)" 20.0 30.4 36.1 38.9 37.8 75.7 18.1 54.9 45.0 20.5 30.4 19.9 22.5 26.3 34.4 18.7 21.2 20.2 35.1 32.8 39.9 30.8 29.0 23.0 71.0 43.5 41.5 23.3 8.9 33.1 16.4 21.6 40.5 16.2 18.2 98.6 12.9 24.5 49.8 21.6 25.7 21.0 39.7 33.1 17.3 10.3 40.7 88.2 30.5 26.0 62.2 21.8 16.2 35.6 224.0 141.7 289.7 144.0 22.3 32.7 109.8 117.7 66.6 111.8 106.0 105.6 154.0 405.1 101.8 68.3 66.3 76.6 164.9 73.6 158.4 466.1 101.3 280.7 175.6 153.2 21.1 572.0 136.6 26.8 11.9 104.1 95.4 54.8 84.6 193.3 274.8 231.2 103.6 232.3 231.5 148.3 292.5 72.9 64.8 245.4 161.2 214.1 80.2 88.8 94.5 161.2 245.4 39.6 70.7 127.5 105.3 287.7 87.4 56.7 158.4 59.1 239.1 297.6 325.6 388.7 64.5 403.6 105.5 56.6 20.8 35.9 35.0 15.6 53.2 54.5 46.4 38.5 17.4 39.5 32.6 40.7 14.7 31.5 20.3 12.2 56.2 36.5 36.1 37.8 54.9 45.0 32.8 39.9 43.5 41.5 40.5 39.7 40.7 35.6 48.7 12.8 84.0 16.3 88.9 97.3 37.6 36.8 40.5 117.5 33.8 37.7 99.9 24.3 32.8 73.5 33.3 58.4 98.2 12.1 86.1 36.4 1.4 52.5 64.0 52.3 14.4 222.5 7.9 26.5 133.1 57.6 20.9 41.9 63.3 28.4 39.7 59.0 52.3 63.9 9.9 19.9 28.5 48.0 108.9 1.9 30.4 54.3 67.6 6.5 57.0 134.3 60.8 3.0 6.6 27.0 14.2 33.4 116.3 21.6 20.4 58.6 59.6 135.1 26.3 56.8 75.1 12.4 22.7 55.2 98.5 40.6 108.9 27.9 37.8 25.8 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 ANXA10 ANX14 ENSG00000109511 "Annexin A10" Q9UJ72 4 168092537-168187736 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 486.3" "Group enriched" "Detected in some" 5 "Exocrine glandular cells: 172.6;Gastric mucus-secreting cells: 667.7;Pancreatic endocrine cells: 315.0" "Group enriched" "Detected in many" 5 "pancreatic cancer: 62.4;stomach cancer: 42.2;urothelial cancer: 19.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "OE19: 284.8;PC-3: 125.5;RT4: 172.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005469, HPA074650" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nucleoli" Vesicles "HPA005469: AB_1844849, HPA074650: " "unprognostic (2.29e-2)" "unprognostic (8.71e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (4.69e-1)" "unprognostic (2.29e-2)" "prognostic favorable (3.64e-6)" "unprognostic (1.18e-3)" "unprognostic (2.88e-1)" "unprognostic (8.61e-4)" "unprognostic (3.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-3)" "unprognostic (8.41e-2)" "unprognostic (4.01e-1)" "unprognostic (2.04e-1)" "unprognostic (8.89e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 19.6 0.0 0.0 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 486.3 0.9 0.0 0.0 0.0 0.0 0.0 89.6 0.1 0.0 0.0 4.6 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.6 0.5 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.4 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.4 0.1 9.7 0.0 4.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 284.8 125.5 0.0 0.6 0.0 0.0 172.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.3 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 1.5 0.0 0.5 15.5 0.0 0.4 0.1 0.0 0.2 7.2 3.2 0.0 2.1 0.0 0.0 0.1 0.0 21.1 11.0 0.1 0.1 0.3 0.0 2.7 0.2 172.6 0.0 0.4 667.7 0.1 0.0 0.0 1.8 72.6 0.0 0.0 0.2 0.5 0.0 2.8 0.0 0.8 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.5 0.0 315.0 1.1 0.0 1.4 0.6 0.0 0.2 0.3 0.6 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.1 14.7 ANXA2R "AXIIR, C5orf39" ENSG00000177721 "Annexin A2 receptor" Q3ZCQ2 5 43039233-43043170 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.8;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 32.2;B-cells: 23.8;dendritic cells: 36.4;Endothelial cells: 24.8;Hepatic stellate cells: 38.2;NK-cells: 47.4;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "gdT-cell: 53.9;MAIT T-cell: 63.5;memory B-cell: 34.3;memory CD4 T-cell: 56.1;memory CD8 T-cell: 59.9;naive B-cell: 32.9;naive CD4 T-cell: 96.3;naive CD8 T-cell: 72.1;NK-cell: 24.8;T-reg: 66.5" "Group enriched" "Detected in all" 6 "B-cells: 34.3;NK-cells: 24.8;T-cells: 96.3" "Cell line enhanced" "Detected in many" "HSkMC: 27.7;JURKAT: 33.1;MOLT-4: 30.0;REH: 30.9;U-937: 117.7" HPA051482 Uncertain Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA051482: AB_2681500" "unprognostic (3.38e-2)" "unprognostic (2.00e-3)" "unprognostic (1.21e-2)" "unprognostic (1.92e-2)" "unprognostic (1.40e-2)" "unprognostic (3.92e-3)" "unprognostic (5.65e-3)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (8.14e-2)" "unprognostic (2.13e-2)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.36e-8)" "unprognostic (2.68e-1)" "unprognostic (2.77e-1)" "unprognostic (2.68e-1)" "unprognostic (1.68e-1)" 4.7 1.3 3.2 12.1 3.2 19.8 3.9 3.0 3.8 3.5 3.5 2.5 3.3 2.4 1.7 1.8 3.3 3.5 2.9 2.8 2.9 2.0 1.3 4.6 26.1 3.4 3.3 1.2 0.8 0.6 1.1 3.2 3.2 2.7 2.7 0.1 1.7 1.2 2.5 2.1 8.2 2.1 3.5 15.8 3.3 1.5 3.3 25.2 2.7 3.0 17.2 3.2 3.8 4.0 2.1 2.1 1.6 1.2 2.6 8.0 0.4 0.5 0.3 0.5 0.6 3.9 1.9 6.8 6.5 1.6 2.2 0.8 5.0 0.5 0.5 13.3 4.0 2.2 5.9 1.8 4.1 2.6 0.8 27.7 0.2 2.4 0.2 0.1 16.2 33.1 1.5 8.9 2.1 3.1 30.0 4.1 0.0 1.7 14.8 30.9 3.6 3.9 0.7 1.1 5.7 0.0 2.7 0.7 0.7 0.2 0.7 4.9 9.9 0.5 0.0 0.8 2.5 4.4 6.7 3.3 3.6 117.7 1.4 5.6 3.5 1.7 53.9 2.5 63.5 34.3 56.1 59.9 3.5 32.9 96.3 72.1 3.2 24.8 8.1 5.2 66.5 26.6 3.2 3.2 3.0 3.8 2.8 2.9 3.4 3.3 3.2 3.5 3.3 4.0 32.2 0.0 9.9 0.0 23.8 3.7 1.4 0.3 2.2 0.1 1.9 2.2 1.3 4.3 1.5 0.0 0.0 0.4 36.4 0.5 0.0 0.1 4.0 1.1 5.0 24.8 1.8 8.2 0.0 0.0 1.1 7.2 1.5 0.8 15.2 4.1 38.2 1.4 8.7 0.0 0.0 0.1 2.0 18.2 5.6 1.5 1.5 7.5 7.2 0.0 7.1 0.2 47.4 0.0 0.0 0.1 0.0 0.4 7.8 1.2 1.0 0.4 2.0 0.0 0.0 3.4 3.7 0.7 1.6 1.2 2.3 0.4 66.0 0.3 0.5 1.4 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 AP3B2 NAPTB ENSG00000103723 "Adaptor related protein complex 3 subunit beta 2" Q13367 15 82659281-82710112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.7;pituitary gland: 18.8;retina: 33.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 27.1;Excitatory neurons: 61.7;Inhibitory neurons: 56.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 22.8;Rod photoreceptor cells: 58.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.5;NTERA-2: 9.5;RT4: 17.3;SCLC-21H: 29.0;SH-SY5Y: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039467, HPA039818" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039467: AB_10795143, HPA039818: AB_10795299" "unprognostic (3.17e-1)" "unprognostic (9.40e-2)" "unprognostic (5.33e-2)" "unprognostic (1.48e-6)" "unprognostic (8.44e-2)" "unprognostic (7.62e-2)" "unprognostic (5.82e-2)" "unprognostic (2.32e-1)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (3.57e-3)" "unprognostic (1.12e-1)" "unprognostic (8.66e-2)" "unprognostic (4.95e-2)" "unprognostic (3.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.43e-2)" 0.7 4.5 15.3 0.9 18.6 1.1 1.4 15.5 20.7 0.9 0.0 1.1 0.7 1.1 2.3 0.7 0.9 0.4 0.2 19.6 5.5 0.6 0.2 0.3 0.5 15.6 5.4 1.2 2.1 12.7 18.8 0.6 13.2 1.4 0.6 33.0 0.9 1.4 0.3 0.9 0.9 1.3 1.1 0.7 1.1 6.2 4.7 1.0 2.1 0.4 1.3 0.8 0.6 11.3 0.2 0.4 9.5 3.2 1.6 0.2 5.7 0.5 0.0 0.8 0.2 0.4 0.4 0.8 4.9 0.2 1.8 0.9 1.0 0.0 0.2 3.2 0.7 0.3 0.4 0.2 0.3 0.4 1.8 1.0 1.1 0.1 0.7 0.1 0.0 2.8 1.0 0.7 0.1 2.5 0.3 0.5 9.5 0.1 0.1 0.3 0.0 0.2 0.0 17.3 29.0 17.5 3.2 1.4 2.4 1.0 0.2 1.9 0.2 0.3 0.9 0.4 1.3 1.6 8.8 0.7 2.2 0.5 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.2 0.9 0.1 0.1 0.4 0.0 0.1 15.3 18.6 15.5 20.7 19.6 5.5 15.6 5.4 13.2 1.1 4.7 11.3 0.1 0.0 1.1 20.9 0.1 0.4 2.1 0.6 1.2 18.4 1.5 2.3 0.8 0.0 0.1 0.0 27.1 0.1 0.2 0.1 0.0 0.2 8.0 0.2 0.6 0.1 13.9 0.0 61.7 0.4 0.1 1.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 13.5 56.9 0.5 6.1 0.0 0.6 5.4 0.9 0.1 0.0 4.7 0.0 4.1 0.0 44.7 22.8 0.0 0.1 0.4 1.2 0.7 0.0 0.4 0.0 58.6 0.0 1.3 0.7 9.8 3.1 0.7 0.1 0.0 0.1 0.2 0.0 0.6 AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 44.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: AB_2685550, HPA067880: AB_2685914" "unprognostic (3.64e-1)" "unprognostic (9.40e-2)" "unprognostic (4.37e-3)" "unprognostic (1.45e-2)" "unprognostic (5.56e-3)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.03e-2)" "unprognostic (2.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.67e-1)" 8.3 4.8 3.2 6.9 2.6 44.0 6.6 5.8 3.6 5.4 1.3 6.0 5.7 7.1 2.0 10.2 5.2 3.1 5.0 3.6 1.2 5.7 5.8 8.7 4.7 3.9 1.5 2.9 10.3 6.4 3.5 3.8 3.0 5.0 3.0 2.5 7.0 4.5 9.6 9.1 6.8 3.2 1.1 10.0 6.0 2.5 1.8 4.8 4.9 3.4 4.3 6.6 5.1 1.6 12.8 9.8 2.8 14.3 8.6 4.1 16.4 5.3 6.2 6.1 4.7 7.7 6.0 7.8 9.4 6.3 12.4 15.8 8.7 4.3 2.9 12.1 10.1 7.0 12.0 3.8 5.8 9.9 13.3 7.0 10.1 4.0 2.9 6.0 5.2 13.6 15.6 9.7 3.6 9.2 5.5 10.5 4.6 4.4 10.1 17.3 0.5 16.8 5.9 15.8 2.7 5.4 4.1 2.6 26.0 3.7 4.4 14.1 7.6 10.2 8.6 13.6 6.0 10.0 11.2 8.1 7.5 8.5 10.5 1.1 1.7 0.6 0.5 1.0 0.2 0.3 0.2 0.2 0.5 0.3 0.3 0.2 25.0 0.4 1.3 0.3 0.2 0.8 3.2 2.6 5.8 3.6 3.6 1.2 3.9 1.5 3.0 1.1 1.8 1.6 2.0 0.0 8.8 6.2 3.9 2.4 12.3 4.3 7.4 5.0 4.2 2.0 1.6 2.8 3.7 7.3 14.6 7.6 5.9 12.8 1.9 8.9 1.4 6.3 2.9 3.0 3.0 0.0 3.6 13.6 18.2 2.9 6.6 10.7 2.5 5.3 1.4 7.1 14.0 11.8 3.2 3.8 6.1 12.4 2.1 0.7 0.6 11.6 7.2 3.7 17.8 3.0 6.2 1.0 2.2 9.4 6.9 3.8 3.6 5.6 10.1 8.8 2.9 8.0 0.0 3.7 3.0 0.6 4.7 6.0 2.3 34.9 4.3 2.0 4.5 10.0 APAF1 "APAF-1, CED4" ENSG00000120868 "Apoptotic peptidase activating factor 1" O14727 12 98645290-98735433 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32.0" "Cell type enhanced" "Detected in many" "monocytes: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 71.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031373, CAB069399" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB069399: AB_1611908, HPA031373: AB_10602230" "unprognostic (1.32e-1)" "unprognostic (5.12e-2)" "prognostic favorable (5.90e-4)" "unprognostic (2.21e-1)" "unprognostic (3.94e-1)" "unprognostic (8.21e-3)" "unprognostic (2.03e-3)" "unprognostic (1.35e-1)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (5.63e-2)" "unprognostic (6.04e-2)" "unprognostic (9.93e-3)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.07e-2)" 4.5 2.8 2.4 8.9 2.8 32.0 5.0 2.5 2.7 5.5 1.2 8.5 5.1 5.5 3.5 3.2 4.0 7.3 2.6 2.8 1.3 3.7 4.7 6.7 9.4 2.3 1.2 7.7 4.0 2.8 3.1 7.6 2.2 3.9 9.6 5.8 4.6 3.4 3.4 5.7 7.1 5.0 1.9 9.7 6.6 3.1 2.2 7.7 4.7 3.1 8.8 5.8 3.9 4.3 6.8 8.7 30.3 11.6 9.4 18.2 8.3 17.3 12.1 11.7 11.6 6.3 4.8 9.8 4.5 12.7 4.4 11.3 20.2 11.4 13.9 7.3 8.0 18.5 9.6 7.7 3.5 18.6 22.7 7.5 3.5 12.1 5.5 14.1 19.6 7.3 9.1 5.2 18.7 1.8 9.4 19.0 8.1 7.5 5.8 11.9 22.8 3.1 7.1 11.5 4.1 7.4 13.5 5.3 4.6 18.6 9.2 25.7 17.7 7.5 6.6 9.0 5.4 3.5 7.1 11.5 3.3 25.4 11.5 16.8 18.1 17.0 4.0 8.0 3.1 5.5 2.8 2.3 14.3 6.2 2.9 1.9 71.1 2.9 8.5 10.4 2.1 3.9 2.4 2.8 2.5 2.7 2.8 1.3 2.3 1.2 2.2 1.9 2.2 4.3 11.7 12.8 8.2 10.4 13.8 3.8 5.7 8.7 8.6 5.8 6.4 6.5 1.5 1.5 7.8 7.3 14.6 3.8 21.4 22.3 0.0 9.4 0.7 5.9 11.6 11.1 12.0 7.6 12.8 8.0 8.0 9.1 14.8 8.7 6.3 18.6 13.2 6.7 12.3 5.0 13.8 18.9 4.1 34.7 25.3 1.3 5.9 34.1 10.6 30.9 54.6 2.7 20.6 14.1 11.2 19.7 20.3 5.3 8.9 8.7 9.2 2.7 8.9 9.8 0.0 6.9 8.1 6.9 10.0 8.7 3.3 1.9 14.6 4.3 13.3 15.0 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.8" "Cell type enhanced" "Detected in many" "Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 6.9 4.6 28.4 6.2 26.0 9.1 5.7 23.1 31.0 5.7 0.1 6.7 6.2 5.6 3.3 7.7 4.3 4.9 7.2 52.8 27.4 6.2 5.7 6.2 5.6 32.1 30.7 6.6 4.1 8.5 3.9 5.1 39.0 5.2 6.2 20.0 3.8 4.1 8.5 5.7 8.5 7.5 16.0 6.1 5.0 5.1 37.9 8.5 5.9 11.8 5.9 5.4 3.6 20.9 11.3 10.1 16.8 12.2 13.4 11.3 6.7 17.9 8.5 9.7 11.5 8.2 8.9 22.0 17.0 23.1 15.5 9.0 17.4 14.6 15.9 13.2 12.2 16.8 14.9 6.2 6.6 8.4 8.6 9.3 9.8 16.6 10.8 6.8 13.6 10.2 20.9 7.2 14.3 7.8 9.6 4.2 6.0 6.1 3.6 8.1 20.8 10.7 8.9 14.1 17.0 10.1 16.9 6.5 7.1 6.8 9.1 6.7 22.8 19.6 9.5 19.5 13.6 5.6 9.5 8.2 10.8 15.3 11.2 11.8 2.5 4.9 2.9 1.3 2.4 2.8 1.5 1.9 2.1 3.1 2.4 2.4 11.4 2.9 2.4 2.7 1.5 1.0 28.4 26.0 23.1 31.0 52.8 27.4 32.1 30.7 39.0 16.0 37.9 20.9 40.6 51.3 23.6 536.4 21.9 11.2 8.9 10.1 19.9 196.9 13.1 14.9 56.6 18.6 20.1 0.0 66.7 5.4 28.9 28.6 0.0 18.7 10.5 20.1 27.6 31.2 27.5 17.4 165.8 19.5 6.5 25.9 19.4 29.7 19.0 28.7 26.7 13.9 16.3 79.1 236.4 17.2 2.0 18.9 12.4 5.5 17.7 27.8 17.8 85.3 30.7 23.4 23.7 196.6 150.8 20.3 34.7 19.5 22.9 10.4 37.2 5.1 18.0 41.5 39.5 44.1 34.0 19.2 30.4 26.5 11.6 2.9 22.4 27.1 16.0 8.9 APC2 APCL ENSG00000115266 "APC regulator of WNT signaling pathway 2" O95996 19 1446302-1473244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 64.5" "Cell type enhanced" "Detected in some" "Astrocytes: 142.4;Bipolar cells: 50.4;Excitatory neurons: 26.8;Horizontal cells: 45.4;Inhibitory neurons: 27.5;Muller glia cells: 29.4;Oligodendrocyte precursor cells: 28.1" "Cancer enriched" "Detected in some" 27 "glioma: 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;SCLC-21H: 9.3;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078002 Supported "Cytokinetic bridge,Midbody,Cytosol" Yes No "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Cytokinetic bridge, Midbody" Cytosol "HPA078002: AB_2686874" "unprognostic (1.78e-3)" "unprognostic (1.65e-1)" "unprognostic (2.88e-5)" "unprognostic (3.64e-2)" "unprognostic (3.59e-1)" "unprognostic (1.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (1.38e-2)" "unprognostic (1.30e-2)" "unprognostic (3.45e-2)" "unprognostic (9.49e-3)" "unprognostic (7.39e-2)" "unprognostic (3.70e-2)" "unprognostic (4.99e-2)" "unprognostic (1.98e-3)" 0.1 2.4 41.5 0.0 27.3 0.0 0.0 41.4 42.4 0.1 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.3 37.1 20.8 0.0 0.0 0.0 0.0 64.5 42.3 0.0 0.3 0.0 6.2 0.0 54.9 0.1 0.0 2.7 0.2 0.0 0.2 0.1 0.4 0.1 38.3 0.0 0.3 1.0 54.6 0.0 0.1 0.0 0.0 0.1 0.2 49.0 0.2 0.6 7.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.0 1.0 0.1 0.0 0.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.6 0.0 0.0 9.3 31.7 1.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.6 0.1 0.1 1.7 0.5 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 27.3 41.4 42.4 37.1 20.8 64.5 42.3 54.9 38.3 54.6 49.0 0.3 0.0 0.0 142.4 0.3 0.0 0.2 0.2 1.2 50.4 0.4 0.4 3.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.5 0.5 0.5 0.0 0.0 26.8 0.0 0.1 0.3 0.0 0.6 0.0 0.2 0.0 0.0 0.1 45.4 27.5 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.7 0.0 29.4 2.1 28.1 17.8 0.0 0.0 0.7 0.0 0.1 0.2 0.2 0.0 11.1 0.0 0.6 0.4 0.4 0.7 2.4 0.0 0.0 0.3 0.2 0.1 0.2 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 APLP1 APLP ENSG00000105290 "Amyloid beta precursor like protein 1" P51693 19 35867899-35879792 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Endocytosis" Heparin-binding Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 1201.6" "Group enriched" "Detected in many" 4 "Bipolar cells: 147.1;Horizontal cells: 161.5;Oligodendrocytes: 461.3" "Cancer enhanced" "Detected in many" "glioma: 63.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 81.6;AN3-CA: 162.9;HMC-1: 76.0;SCLC-21H: 87.2;SH-SY5Y: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028970, HPA028971" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 6400000 "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA028970: AB_2672847, HPA028971: AB_10601334" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (9.36e-3)" "prognostic unfavorable (3.87e-4)" "unprognostic (7.32e-3)" "unprognostic (1.26e-2)" "unprognostic (1.04e-3)" "unprognostic (2.24e-2)" "unprognostic (4.98e-2)" "unprognostic (6.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.57e-11)" "unprognostic (1.38e-3)" "unprognostic (7.12e-2)" "unprognostic (5.43e-2)" "prognostic unfavorable (2.65e-5)" 3.0 31.5 417.1 3.1 718.0 0.4 1.4 680.9 552.4 3.1 218.6 4.4 1.8 3.1 1.3 1.5 2.7 5.5 10.8 438.3 465.8 4.9 0.6 1.9 1.4 783.2 627.4 1.4 75.0 22.3 151.4 0.9 710.7 2.1 2.2 56.3 1.8 1.9 0.5 1.1 2.1 3.2 605.9 0.5 28.1 13.1 598.3 0.8 1.5 0.5 1.5 1.2 2.1 1201.6 4.4 40.0 81.6 162.9 7.1 3.2 10.4 5.6 3.5 7.8 1.1 7.3 6.3 0.8 66.5 21.0 27.7 2.2 26.1 2.6 5.2 48.9 3.7 0.3 10.6 5.2 2.0 0.2 76.0 3.6 1.8 3.2 0.1 28.8 3.1 6.1 2.7 1.2 25.0 8.3 0.2 0.3 3.9 16.5 16.5 7.2 0.4 1.1 1.4 1.1 87.2 89.3 23.1 3.8 0.8 23.9 20.8 4.3 1.3 61.3 28.8 32.9 4.3 2.4 1.6 0.3 42.3 1.1 33.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.0 417.1 718.0 680.9 552.4 438.3 465.8 783.2 627.4 710.7 605.9 598.3 1201.6 2.5 6.4 0.0 12.4 0.6 1.3 2.6 0.7 1.2 147.1 0.4 1.1 6.2 1.5 0.2 0.0 12.5 0.3 0.3 0.4 0.0 2.0 27.6 1.3 1.2 2.8 34.9 0.0 55.5 4.2 6.4 2.8 10.2 3.2 0.0 0.1 0.7 0.4 0.4 161.5 46.8 1.1 2.0 0.3 1.6 15.8 1.2 1.1 5.4 12.2 0.0 14.6 0.0 19.1 461.3 3.1 0.1 0.0 0.4 1.9 0.0 0.1 0.2 38.6 0.0 1.9 1.8 14.5 28.7 0.1 0.6 0.4 0.5 0.1 0.2 1.3 APOC3 ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 27649.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 84691.9" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "CACO-2: 107.3;Hep G2: 296.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" NA NA 106000000000 45000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" 4.1 1.2 0.0 1.0 0.0 0.0 2.5 0.0 0.1 0.4 0.0 7.2 907.0 0.5 0.0 1.1 1.9 0.0 1.6 0.0 0.0 18.2 27649.0 1.4 0.9 0.0 0.0 0.8 2.4 0.0 0.8 0.9 0.0 0.6 0.0 0.0 0.6 0.0 0.6 1.2 1106.7 0.5 0.0 8.0 1.5 1.0 0.0 0.5 0.8 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.1 107.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 296.2 0.0 10.7 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 2.3 0.2 0.0 0.0 0.0 6.3 3.9 0.0 0.1 1.1 3.8 4.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 67.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 674.9 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.0 4.2 0.0 0.0 39.7 0.0 823.7 0.0 0.4 1.5 0.1 0.0 0.0 0.0 0.3 707.9 84691.9 1.1 0.0 0.0 264.5 0.0 1107.4 0.0 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.0 0.0 0.0 0.0 10473.3 121.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 39.8 0.0 135.5 0.0 APOL6 "APOL-VI, APOLVI" ENSG00000221963 "Apolipoprotein L6" Q9BWW8 22 35648446-35668404 "Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.9;NK-cells: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB028574, HPA029165, HPA029167" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "CAB028574: , HPA029165: AB_10670037, HPA029167: AB_10670832" "unprognostic (7.25e-3)" "unprognostic (2.67e-2)" "unprognostic (1.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-1)" "unprognostic (1.55e-1)" "unprognostic (2.32e-2)" "unprognostic (8.29e-2)" "unprognostic (3.76e-2)" "unprognostic (6.26e-3)" "unprognostic (1.46e-3)" "unprognostic (1.46e-1)" "unprognostic (6.65e-3)" "unprognostic (2.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "prognostic favorable (6.61e-4)" 23.4 7.3 4.1 15.8 4.3 16.1 10.0 3.4 4.0 6.8 3.3 13.2 19.2 5.5 5.5 5.9 6.6 9.1 4.2 3.9 5.1 6.4 46.5 15.5 15.5 8.7 5.0 12.2 2.9 2.6 2.4 7.8 5.8 7.9 11.8 2.6 14.0 5.1 3.1 4.5 19.7 7.4 6.7 18.2 14.0 2.3 4.9 10.1 8.5 3.9 10.4 13.2 3.7 5.4 12.8 4.1 0.3 1.5 30.1 15.0 17.3 5.3 14.2 17.3 21.7 2.0 14.2 17.7 2.6 14.0 12.6 16.2 0.1 8.6 4.5 33.6 0.1 7.4 2.6 4.0 23.7 10.4 12.4 19.3 5.7 5.9 3.3 3.9 3.6 8.0 0.8 31.2 3.2 1.3 14.6 3.2 0.5 0.9 5.3 6.1 6.8 8.7 7.6 28.9 0.4 0.2 8.5 7.2 10.0 1.1 1.2 12.1 3.9 4.3 2.6 3.0 2.8 16.4 14.2 1.7 8.1 16.2 6.1 7.5 4.8 2.6 7.3 7.6 6.1 1.0 4.8 5.8 2.4 0.7 4.6 5.3 7.5 5.0 8.5 0.3 5.5 4.2 4.1 4.3 3.4 4.0 3.9 5.1 8.7 5.0 5.8 6.7 4.9 5.4 58.6 70.5 34.3 6.8 15.7 8.0 10.8 14.7 13.6 0.2 16.8 10.8 7.3 34.3 38.6 12.9 0.0 8.3 79.1 101.1 9.8 33.6 10.5 18.4 48.9 33.4 47.3 11.6 0.2 41.9 35.6 33.4 41.8 17.2 36.8 12.2 39.3 135.9 34.9 0.0 1.3 55.3 20.3 58.1 19.9 7.4 26.1 50.5 8.8 17.8 68.5 3.8 126.7 9.5 2.1 45.7 43.7 18.8 51.0 43.2 88.6 31.6 47.4 0.0 0.0 25.3 22.0 0.5 0.2 15.6 5.3 2.5 67.7 6.0 35.9 62.0 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARCN1 COPD ENSG00000095139 "Archain 1" P48444 11 118572390-118603033 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037573, HPA044874" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 140000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Golgi apparatus, Cytosol" "HPA037573: AB_10696938, HPA044874: AB_2679126" "unprognostic (1.46e-2)" "unprognostic (4.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.20e-1)" "unprognostic (9.99e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (2.97e-5)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-3)" "unprognostic (9.39e-2)" "unprognostic (3.56e-2)" "unprognostic (7.99e-2)" "unprognostic (9.20e-2)" "unprognostic (4.14e-3)" "unprognostic (5.56e-3)" 75.4 67.7 47.5 53.8 51.0 30.4 67.5 52.0 60.5 78.0 61.2 65.0 59.2 69.2 111.1 72.5 60.5 51.6 75.6 46.8 50.9 58.3 91.6 62.6 53.2 51.2 51.3 65.5 119.7 61.9 88.7 54.7 51.1 68.8 67.1 39.2 79.6 64.5 51.1 60.9 64.9 71.0 50.0 57.9 71.8 46.2 50.5 58.8 65.2 55.0 62.2 66.4 60.9 57.2 90.9 72.6 135.3 98.9 174.0 172.7 66.6 244.8 208.5 102.4 120.7 239.4 116.6 96.4 199.7 275.7 148.0 123.7 160.5 139.5 151.5 128.0 66.3 211.6 56.7 151.4 197.1 140.4 121.8 157.8 117.6 175.0 168.7 149.3 162.2 95.0 106.8 139.2 201.3 157.0 123.2 130.8 85.3 207.7 92.4 107.9 134.2 147.4 137.3 107.0 88.3 86.6 130.2 129.0 70.1 132.5 155.9 111.4 144.0 129.4 65.1 118.4 109.5 79.9 78.5 147.6 74.3 122.6 161.4 118.1 49.8 50.7 52.7 59.8 69.0 39.5 51.7 51.3 54.0 35.4 48.0 44.7 41.5 64.5 64.5 44.9 53.9 55.8 47.5 51.0 52.0 60.5 46.8 50.9 51.2 51.3 51.1 50.0 50.5 57.2 43.6 35.3 47.9 12.4 32.2 31.6 38.5 31.5 23.9 22.4 39.4 27.9 46.5 24.3 41.9 31.3 4.2 17.2 45.6 68.4 9.8 34.3 11.1 38.4 72.2 43.1 40.2 14.9 15.4 37.8 36.1 44.9 39.3 50.4 39.3 31.9 31.4 55.7 30.3 18.5 17.7 80.2 22.4 36.0 37.6 8.5 48.1 35.3 23.2 11.2 49.0 17.3 26.8 17.1 20.2 46.9 35.8 41.3 68.3 51.5 56.2 30.5 46.2 13.6 19.7 52.7 45.7 44.8 47.6 30.4 34.7 30.2 38.4 43.9 42.6 51.6 ARFGAP1 "ARF1GAP, bA261N11.3, FLJ10767" ENSG00000101199 "ADP ribosylation factor GTPase activating protein 1" Q8N6T3 20 63272785-63289790 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051019, HPA056273" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" Cytosol "HPA051019: AB_2681313, HPA056273: AB_2683084" "unprognostic (1.81e-1)" "unprognostic (4.64e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-1)" "unprognostic (1.38e-1)" "unprognostic (1.24e-1)" "unprognostic (1.57e-3)" "unprognostic (7.76e-2)" "unprognostic (8.86e-3)" "unprognostic (8.62e-2)" "prognostic favorable (4.57e-4)" "unprognostic (3.23e-2)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.16e-1)" "unprognostic (7.59e-2)" "unprognostic (4.34e-2)" "unprognostic (2.86e-1)" 12.9 16.7 13.1 15.5 14.3 12.1 13.0 13.1 20.6 19.1 8.4 19.1 13.1 20.8 8.6 15.8 16.1 16.8 14.1 14.4 11.0 15.9 17.8 16.1 16.1 14.1 12.0 17.7 28.3 11.8 63.9 15.4 14.2 20.1 9.5 11.7 18.4 13.4 14.1 19.1 18.1 12.5 9.1 20.5 18.5 24.2 12.5 14.2 17.9 7.5 11.3 16.5 14.9 15.9 32.6 60.2 25.6 30.6 30.3 32.5 51.2 46.4 36.5 90.7 45.5 145.2 35.2 24.5 41.7 55.4 41.5 43.2 23.5 73.8 28.5 15.8 26.7 19.4 64.7 128.4 46.2 28.8 38.4 28.5 46.9 44.0 24.9 30.5 32.9 25.5 34.9 27.8 25.1 53.2 52.9 28.0 34.5 34.3 51.9 29.7 36.8 23.6 22.3 38.8 27.3 29.9 55.1 58.7 59.2 20.7 42.8 36.4 42.8 56.0 77.3 35.0 37.6 28.4 20.2 26.5 56.9 20.0 35.3 4.8 5.7 6.4 5.6 7.1 6.4 3.0 3.1 5.3 5.7 4.2 3.0 3.0 2.4 4.7 9.5 4.2 4.1 6.0 13.1 14.3 13.1 20.6 14.4 11.0 14.1 12.0 14.2 9.1 12.5 15.9 12.6 22.4 30.7 34.9 11.2 10.1 6.0 8.6 4.0 26.6 17.6 14.4 12.4 11.5 14.4 12.9 33.3 12.5 15.4 37.6 9.8 12.2 15.9 11.0 17.1 14.2 24.5 9.5 14.5 15.4 24.9 16.3 50.4 14.9 15.9 30.6 13.6 23.3 14.9 21.9 14.9 40.4 2.0 14.4 11.5 23.3 12.5 13.5 12.4 5.6 12.3 11.8 15.5 18.6 24.8 28.2 18.3 9.8 17.8 11.6 17.4 11.5 18.8 20.1 6.6 11.1 14.9 21.3 7.4 6.7 8.5 15.2 10.3 16.8 24.0 9.2 ARFGEF1 "ARFGEP1, BIG1, DKFZP434L057, p200" ENSG00000066777 "ADP ribosylation factor guanine nucleotide exchange factor 1" Q9Y6D6 8 67173511-67343781 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023399, HPA023822" Supported Supported Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA023399: AB_1844981, HPA023822: AB_1844982" "prognostic unfavorable (8.76e-4)" "unprognostic (1.62e-1)" "unprognostic (4.60e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.52e-2)" "unprognostic (4.52e-1)" "unprognostic (5.38e-2)" "unprognostic (4.67e-2)" "unprognostic (2.13e-3)" "unprognostic (1.31e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.13e-1)" "unprognostic (2.84e-1)" "unprognostic (1.62e-1)" "unprognostic (1.61e-2)" 11.4 10.3 5.6 14.6 5.3 27.5 13.6 8.2 6.8 14.2 10.1 19.2 16.9 10.5 11.0 15.2 11.8 12.5 9.6 4.6 5.5 22.8 15.2 13.8 15.4 6.2 6.5 10.3 17.5 28.0 5.4 14.4 6.7 13.0 17.2 36.5 14.8 12.1 12.8 13.7 17.5 10.8 5.2 13.8 19.6 28.3 6.4 22.2 22.4 14.0 17.2 19.7 7.9 7.3 31.8 20.4 19.3 7.3 21.9 29.8 22.5 21.4 24.3 21.7 22.0 12.6 30.0 23.9 8.9 27.6 26.2 22.2 23.5 30.4 26.6 28.3 16.0 40.2 12.0 13.5 18.6 20.9 37.3 18.4 21.6 19.2 31.8 22.3 31.5 24.6 24.5 25.3 25.5 7.2 48.1 9.7 42.5 34.5 18.5 22.4 13.9 4.8 35.8 58.2 7.6 14.9 14.1 33.9 19.5 29.5 58.5 18.3 38.6 14.4 19.3 19.5 16.4 20.4 22.6 17.5 23.6 20.8 14.2 6.1 1.6 4.3 2.8 2.3 3.6 1.2 1.8 2.3 1.6 1.3 3.0 2.6 5.1 2.5 0.9 2.2 3.9 0.9 5.6 5.3 8.2 6.8 4.6 5.5 6.2 6.5 6.7 5.2 6.4 7.3 38.5 44.8 23.1 73.1 32.7 23.7 34.0 23.8 19.9 36.8 32.7 18.9 33.1 18.6 31.9 38.6 139.7 20.0 47.0 43.2 11.7 29.7 25.4 42.5 34.7 28.5 29.4 16.2 119.0 25.6 15.4 22.9 57.6 53.0 15.2 40.0 23.2 19.6 15.8 43.7 146.3 27.9 14.2 31.3 20.4 36.0 40.0 35.2 17.8 105.9 47.1 22.9 46.4 151.8 126.6 40.1 25.7 30.1 29.8 38.2 30.8 24.7 33.9 100.8 6.6 23.6 26.5 69.4 50.7 26.0 29.5 24.9 42.4 32.1 28.0 60.4 ARFGEF2 BIG2 ENSG00000124198 "ADP ribosylation factor guanine nucleotide exchange factor 2" Q9Y6D5 20 48921711-49036693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 81.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 102.6;Inhibitory neurons: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026078, CAB026382" Supported Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Vesicles, Cytosol" "CAB026382: , HPA026078: AB_1844983" "unprognostic (1.50e-2)" "unprognostic (9.56e-3)" "unprognostic (4.14e-2)" "unprognostic (4.94e-3)" "unprognostic (5.30e-2)" "unprognostic (6.94e-2)" "unprognostic (1.57e-2)" "unprognostic (2.99e-1)" "unprognostic (8.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.15e-7)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (3.90e-2)" 9.1 20.2 2.8 8.7 4.1 10.4 15.8 1.9 5.8 11.5 7.9 14.2 13.7 9.0 5.9 11.0 7.5 8.5 13.4 4.5 3.9 15.3 12.4 7.8 9.8 2.6 3.2 7.7 19.2 81.5 8.7 9.2 3.5 10.6 15.7 6.8 11.0 9.7 11.8 11.1 10.9 9.5 1.9 10.4 16.2 13.6 3.5 11.3 23.8 18.2 14.2 11.1 8.2 5.0 18.3 16.5 8.9 5.1 18.0 14.8 21.8 15.5 19.5 36.6 19.0 37.1 19.8 25.5 22.1 19.7 33.8 21.0 18.6 23.6 33.8 9.0 7.6 17.5 17.9 25.4 19.7 22.6 19.7 15.0 21.6 23.9 27.6 12.7 28.4 11.7 15.0 22.3 20.8 6.3 13.0 6.8 8.3 20.5 17.4 14.0 25.5 30.3 13.6 23.4 7.1 9.0 42.6 66.0 23.4 10.3 26.6 18.6 34.5 35.6 16.5 18.2 13.1 35.9 35.0 18.7 23.4 10.7 11.6 1.1 0.6 0.2 0.5 0.4 0.6 0.5 0.5 0.4 0.7 0.9 0.8 0.7 0.3 0.3 0.3 0.9 0.1 0.3 2.8 4.1 1.9 5.8 4.5 3.9 2.6 3.2 3.5 1.9 3.5 5.0 16.6 19.2 26.0 37.2 21.2 11.3 12.2 11.0 11.4 15.3 27.7 14.7 40.7 17.2 20.0 11.0 14.6 10.5 14.7 30.4 1.9 10.9 16.6 19.5 17.1 19.5 12.5 14.3 102.6 13.3 10.0 12.6 16.3 24.7 15.2 11.0 20.7 27.8 10.8 11.8 96.7 23.3 8.2 15.7 13.9 24.6 10.2 17.8 10.6 60.9 15.6 5.4 10.3 43.2 57.0 15.5 21.6 11.3 29.0 24.1 18.6 11.5 17.2 16.1 6.6 14.2 12.5 32.6 20.4 17.5 15.5 30.0 13.2 16.6 21.0 21.2 ARFIP1 HSU52521 ENSG00000164144 "ADP ribosylation factor interacting protein 1" P53367 4 152779937-152918463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005080, HPA037375, HPA063759" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" Nucleoplasm "CAB005080: AB_2058797, HPA037375: AB_2675440, HPA063759: AB_2685114" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.75e-5)" "unprognostic (1.49e-3)" "unprognostic (4.32e-1)" "unprognostic (1.24e-1)" "unprognostic (3.54e-2)" "unprognostic (5.34e-1)" "unprognostic (1.03e-2)" "unprognostic (3.56e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-2)" "prognostic favorable (2.83e-10)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (7.02e-2)" "unprognostic (4.22e-3)" 16.8 14.8 7.9 15.8 8.7 3.7 23.4 9.9 10.8 22.5 9.9 28.1 23.2 21.7 20.5 20.9 18.5 19.9 10.2 7.3 9.3 19.8 15.4 16.8 15.1 9.3 8.0 17.6 10.5 22.4 10.5 18.0 9.5 21.1 27.8 20.2 13.7 17.2 6.6 17.3 21.3 19.8 9.4 18.3 22.7 12.1 8.3 12.0 20.1 10.4 14.8 23.5 15.2 11.4 25.8 18.4 25.1 25.7 37.2 37.9 30.6 29.5 40.5 28.7 26.9 21.3 51.3 20.6 9.9 40.5 22.7 18.1 26.3 29.1 35.3 16.9 16.2 20.0 18.0 20.5 26.1 38.2 41.7 26.6 30.9 24.8 23.8 30.7 26.4 11.8 23.5 43.3 39.8 28.6 22.7 19.8 21.8 29.9 18.5 12.6 14.7 19.2 50.7 32.1 32.8 26.0 22.1 40.7 30.2 23.5 37.7 19.6 17.3 27.8 20.1 26.8 21.4 48.2 42.8 28.1 35.3 38.2 40.0 31.5 27.3 42.2 14.5 31.1 14.6 19.0 11.2 12.2 24.8 17.7 8.7 11.8 81.6 29.1 30.7 3.1 18.5 18.7 7.9 8.7 9.9 10.8 7.3 9.3 9.3 8.0 9.5 9.4 8.3 11.4 28.5 6.4 31.8 40.5 20.3 29.6 18.4 30.7 34.1 17.2 26.2 19.7 10.2 20.0 29.1 38.6 0.0 28.6 15.6 40.9 27.4 27.4 46.3 42.2 33.0 23.8 38.9 12.0 44.5 18.3 27.0 28.8 40.2 50.7 22.8 14.2 17.2 19.8 22.1 18.5 42.8 39.1 34.6 23.8 18.0 21.6 22.4 24.5 21.4 89.9 19.5 35.9 23.7 76.4 75.6 24.4 28.2 21.8 11.8 23.6 23.8 34.2 31.9 24.2 32.9 20.6 27.8 31.7 29.5 31.9 34.0 43.9 17.7 89.2 31.7 30.3 ARFIP2 POR1 ENSG00000132254 "ADP ribosylation factor interacting protein 2" P53365 11 6474683-6481479 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032985, HPA038156" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "CAB032985: AB_2058811, HPA038156: AB_10697243" "unprognostic (2.32e-1)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "prognostic favorable (2.00e-5)" "unprognostic (8.44e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-3)" "unprognostic (2.50e-1)" "unprognostic (2.96e-1)" "unprognostic (1.76e-1)" "unprognostic (5.70e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.53e-4)" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.32e-2)" "unprognostic (9.48e-3)" 19.8 29.3 31.7 18.6 32.3 22.8 50.7 32.5 35.2 36.3 36.2 36.8 32.9 27.2 34.0 31.4 39.3 23.9 17.9 32.1 31.4 27.0 34.6 24.4 22.4 31.2 31.4 29.4 49.4 46.4 40.7 29.7 31.9 46.6 48.1 28.3 57.7 28.2 15.2 32.8 30.7 27.4 30.9 20.7 50.4 18.3 31.8 25.7 36.9 16.1 32.0 29.2 24.4 33.1 50.4 64.8 38.9 38.5 59.1 53.9 56.1 40.3 107.0 86.2 101.8 62.1 80.3 39.9 16.5 79.3 49.8 68.0 49.4 84.1 70.0 30.9 86.5 22.3 87.7 60.4 71.3 36.2 42.8 60.0 65.7 43.0 98.3 64.2 55.9 38.3 35.3 45.0 55.8 98.9 41.9 41.6 67.2 119.0 71.9 31.7 22.6 37.1 61.9 50.4 50.8 63.2 48.7 204.9 25.9 36.3 86.9 33.0 36.8 35.4 35.7 39.1 30.3 67.3 32.5 24.3 65.4 22.0 43.9 13.0 15.6 9.9 17.9 10.9 17.8 12.1 16.7 14.5 21.3 13.8 16.7 17.1 6.1 21.1 6.7 16.6 18.9 13.9 31.7 32.3 32.5 35.2 32.1 31.4 31.2 31.4 31.9 30.9 31.8 33.1 14.8 6.4 6.4 4.6 20.7 28.0 49.3 48.9 16.5 32.6 59.8 45.1 4.3 40.0 30.5 12.9 29.2 80.1 24.3 56.0 58.7 62.7 31.7 28.1 20.1 19.6 63.0 21.8 8.4 85.4 65.8 23.1 62.2 37.2 31.8 30.3 20.3 21.1 28.1 21.9 7.8 126.6 32.6 10.1 16.4 43.3 20.5 14.4 24.9 5.6 25.2 35.4 18.6 6.6 7.6 59.9 63.4 24.5 28.0 73.3 65.2 34.4 34.7 32.3 26.3 21.6 23.3 41.0 26.2 26.2 32.1 112.5 16.9 40.9 52.6 64.7 ARGLU1 FLJ10154 ENSG00000134884 "Arginine and glutamate rich 1" Q9NWB6 13 106541673-106568137 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034962, HPA056792" Supported Enhanced Nucleoplasm,Mitochondria,Cytosol No No "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Mitochondria, Cytosol" "HPA034962: AB_10611676, HPA056792: AB_2683236" "unprognostic (1.66e-2)" "unprognostic (3.10e-2)" "unprognostic (2.24e-1)" "unprognostic (2.82e-1)" "unprognostic (3.97e-2)" "unprognostic (3.00e-2)" "unprognostic (1.11e-3)" "unprognostic (3.21e-2)" "unprognostic (9.00e-2)" "unprognostic (1.52e-1)" "prognostic favorable (3.92e-5)" "unprognostic (1.43e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.91e-3)" "unprognostic (2.65e-1)" "unprognostic (2.87e-1)" "prognostic favorable (7.34e-5)" 35.0 25.5 17.9 4.5 18.4 11.0 36.3 19.5 25.2 43.7 13.5 41.2 3.5 43.1 6.2 30.8 47.0 2.9 31.1 17.8 16.4 28.2 22.9 46.3 6.7 15.2 15.6 50.4 29.3 3.7 34.1 6.1 15.3 34.7 4.7 8.6 35.1 4.5 28.4 32.1 42.6 6.3 15.3 40.8 38.2 23.7 16.2 7.0 36.3 7.5 5.7 35.6 37.6 18.2 10.5 9.4 26.0 6.4 9.0 4.6 9.1 10.2 6.5 9.1 6.6 16.8 8.3 21.5 6.1 9.2 8.4 6.9 17.4 9.9 11.4 24.5 12.3 18.8 9.2 11.6 9.3 36.0 8.2 5.0 6.8 6.9 7.2 9.2 8.1 13.0 13.4 11.4 11.4 7.7 16.4 13.9 18.6 23.6 4.0 17.3 19.7 8.9 10.6 7.3 7.0 13.8 9.9 12.7 6.1 17.6 5.8 27.0 9.2 7.5 6.2 5.9 10.0 11.1 14.2 27.4 10.6 15.6 6.7 44.6 24.2 17.2 15.4 17.7 14.1 30.2 13.5 12.1 17.1 32.4 15.3 14.6 45.7 18.8 14.8 34.2 15.7 12.8 17.9 18.4 19.5 25.2 17.8 16.4 15.2 15.6 15.3 15.3 16.2 18.2 342.0 141.1 230.6 198.8 242.0 261.7 268.5 179.3 186.1 222.7 153.9 104.0 88.3 90.1 204.9 114.0 135.5 141.9 329.3 195.3 99.7 120.7 42.0 201.2 308.3 298.1 187.7 160.3 208.8 113.2 137.7 204.7 355.7 290.6 168.7 331.2 280.2 81.5 101.3 304.5 155.6 218.5 148.5 90.7 186.2 34.0 255.1 142.1 128.1 161.1 182.1 223.3 301.8 200.6 367.2 145.0 173.8 217.7 194.9 251.0 153.7 58.6 190.7 271.2 216.9 179.6 196.8 199.8 125.9 164.1 262.3 185.2 257.8 280.7 193.1 316.0 ARHGAP10 "FLJ20896, FLJ41791, GRAF2" ENSG00000071205 "Rho GTPase activating protein 10" A1A4S6 4 147732063-148072776 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 137.6;Oligodendrocyte precursor cells: 124.7;Peritubular cells: 121.1;Rod photoreceptor cells: 132.9;Sertoli cells: 144.7;Smooth muscle cells: 107.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 80.2" HPA039589 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039589: " "unprognostic (8.57e-3)" "unprognostic (1.34e-1)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (2.79e-1)" "unprognostic (3.41e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (2.57e-2)" "prognostic favorable (8.15e-5)" "prognostic unfavorable (6.26e-4)" "unprognostic (1.54e-1)" "unprognostic (1.02e-3)" "unprognostic (1.09e-2)" 35.0 11.4 4.6 7.0 6.3 3.3 22.6 2.0 7.1 35.1 9.8 47.0 4.9 16.9 9.8 35.7 35.1 13.0 38.7 6.0 2.6 9.7 7.9 15.1 5.8 3.1 4.7 33.4 9.2 16.0 6.2 10.7 3.5 26.0 8.0 14.4 11.1 20.0 38.6 22.2 16.6 13.3 3.6 9.8 26.3 11.8 5.5 11.3 16.9 33.1 6.7 44.2 30.8 4.1 21.0 8.3 4.4 9.2 33.2 45.1 46.0 28.3 23.5 17.9 13.8 21.6 11.8 0.0 4.7 24.4 15.0 10.1 16.4 23.4 21.5 11.4 10.9 7.2 6.2 0.7 51.2 7.1 8.0 23.4 17.9 22.3 19.0 22.7 22.0 6.0 1.0 38.3 32.3 25.5 4.5 0.0 4.1 13.9 4.0 8.1 12.7 24.5 12.3 19.0 10.7 5.1 7.4 29.6 7.9 19.0 3.7 0.6 21.9 16.8 12.9 10.3 13.8 14.2 1.8 0.1 25.5 0.9 15.1 0.0 1.7 16.7 5.3 0.1 10.5 0.0 4.1 6.2 3.0 0.0 1.2 6.0 0.2 5.3 0.1 0.1 5.4 2.4 4.6 6.3 2.0 7.1 6.0 2.6 3.1 4.7 3.5 3.6 5.5 4.1 18.5 3.2 4.1 5.5 1.5 14.4 7.9 7.0 16.5 7.1 13.0 15.4 64.8 5.7 3.5 1.8 43.8 29.0 11.1 0.2 0.0 5.8 13.6 16.3 83.5 11.8 0.0 1.3 63.3 16.0 48.2 45.6 11.2 31.8 1.3 21.7 4.2 13.0 20.9 3.3 26.7 0.4 0.0 6.2 33.7 10.2 137.6 24.2 5.4 46.9 58.4 8.2 8.2 124.7 2.1 14.0 0.1 121.1 3.2 4.5 0.8 15.0 1.3 132.9 144.7 22.7 107.3 4.7 13.3 15.7 10.2 12.7 16.0 9.1 1.1 3.1 ARHGAP15 BM046 ENSG00000075884 "Rho GTPase activating protein 15" Q53QZ3 2 143091362-143768352 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 79.8;lymphoid tissue: 75.2" "Cell type enhanced" "Detected in many" "B-cells: 126.3;Early spermatids: 132.3;granulocytes: 88.5;Microglial cells: 250.1;NK-cells: 89.6;T-cells: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 59.4;HEL: 75.8;HL-60: 124.3;MOLT-4: 82.0;NB-4: 100.4;THP-1: 131.0;U-698: 89.5;U-937: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032125 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA 38000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus, Vesicles" Nucleoplasm "HPA032125: AB_10671370" "unprognostic (1.59e-2)" "unprognostic (2.40e-3)" "unprognostic (8.63e-2)" "unprognostic (2.19e-2)" "unprognostic (2.99e-1)" "unprognostic (6.62e-3)" "unprognostic (6.14e-2)" "unprognostic (2.18e-3)" "unprognostic (1.32e-2)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (4.40e-2)" "unprognostic (2.12e-2)" "unprognostic (4.58e-2)" "unprognostic (6.94e-2)" 6.9 5.9 1.4 27.1 1.3 79.8 7.6 2.3 2.3 4.1 1.9 7.3 6.8 2.6 9.7 4.0 2.8 11.4 5.6 1.2 2.2 4.4 10.2 9.8 59.3 3.0 1.9 1.8 1.3 1.7 1.0 4.0 2.7 4.3 7.7 1.3 4.2 5.1 1.2 2.0 15.1 3.9 1.9 44.9 7.5 7.4 2.1 75.2 4.5 2.2 46.3 11.4 4.3 4.0 0.3 0.1 4.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 59.4 0.2 0.1 0.1 0.1 0.2 0.1 0.3 14.6 0.0 75.8 0.5 0.1 0.0 124.3 1.2 0.0 0.0 0.2 0.2 0.1 0.0 47.0 0.3 4.4 0.0 0.1 82.0 100.4 0.3 0.0 0.1 44.7 0.6 22.7 0.0 0.1 0.2 0.4 0.3 0.2 1.0 0.1 4.5 131.0 0.6 0.4 1.2 0.1 0.2 1.0 0.3 89.5 0.7 63.9 3.9 181.8 32.0 140.1 97.7 34.3 161.6 94.3 172.8 125.7 56.3 86.2 119.0 101.7 207.2 121.4 40.5 54.3 147.7 99.9 1.4 1.3 2.3 2.3 1.2 2.2 3.0 1.9 2.7 1.9 2.1 4.0 8.2 0.0 9.6 2.0 126.3 5.6 0.1 0.0 0.0 0.3 1.8 2.0 3.9 1.5 2.5 0.0 0.0 0.2 78.9 0.3 0.0 0.1 132.3 1.8 2.3 4.3 0.0 26.3 12.2 0.0 0.3 9.7 8.6 3.5 88.5 0.0 8.6 0.8 21.3 1.7 6.8 0.0 0.0 39.9 30.9 17.5 14.9 43.0 8.8 250.1 34.9 0.4 89.6 20.6 3.2 0.0 0.0 3.4 65.8 0.2 0.0 0.7 2.2 0.3 46.0 2.7 31.6 68.4 1.2 0.4 4.5 0.3 149.2 0.1 0.2 0.2 ARHGAP18 "bA307O14.2, MacGAP" ENSG00000146376 "Rho GTPase activating protein 18" Q8N392 6 129576132-129710177 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 253.6;Respiratory ciliated cells: 265.3;Syncytiotrophoblasts: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 395.8;LHCN-M2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031595 Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA 1900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Plasma membrane" "HPA031595: AB_10959905" "unprognostic (6.39e-2)" "unprognostic (1.60e-1)" "unprognostic (5.45e-2)" "unprognostic (5.49e-2)" "unprognostic (3.05e-1)" "unprognostic (3.17e-1)" "unprognostic (9.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.98e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (4.08e-1)" "unprognostic (2.29e-3)" "unprognostic (2.22e-1)" "unprognostic (3.05e-2)" "unprognostic (5.52e-2)" "unprognostic (1.08e-1)" 20.5 37.2 3.4 13.0 2.5 4.3 13.4 2.4 2.8 14.9 15.1 14.8 24.8 6.7 20.2 6.0 28.3 15.4 6.0 2.9 4.1 28.4 6.3 28.7 9.4 4.7 5.7 6.0 33.2 14.2 6.7 20.8 4.3 9.9 15.0 2.6 14.6 8.4 10.6 4.0 27.3 10.6 3.5 9.0 27.9 8.3 6.4 6.1 23.0 13.0 7.9 12.6 4.1 3.7 8.6 18.8 1.9 2.6 17.8 25.0 15.1 64.0 48.8 27.7 18.5 10.0 14.1 7.1 30.6 43.2 8.8 11.0 13.4 20.9 51.3 7.0 5.7 46.7 13.8 57.3 25.4 6.9 395.8 15.9 3.2 50.4 44.7 57.8 79.8 0.0 25.3 17.4 113.1 2.3 0.1 6.8 2.0 16.0 4.5 0.3 8.5 13.7 84.6 4.8 0.0 0.1 5.3 8.8 32.3 9.3 9.7 8.1 61.6 28.8 4.1 2.3 51.8 7.8 6.0 4.8 9.7 12.7 40.9 12.0 5.1 13.5 4.9 5.8 3.1 2.9 2.5 5.5 4.8 1.7 0.4 2.6 3.9 2.5 3.2 11.8 2.8 6.0 3.4 2.5 2.4 2.8 2.9 4.1 4.7 5.7 4.3 3.5 6.4 3.7 139.5 57.7 33.3 1.6 13.0 13.0 17.7 15.7 10.8 0.7 53.4 14.7 4.1 17.2 39.5 38.6 2.1 92.7 31.0 19.0 150.6 48.2 20.7 176.1 5.8 89.2 13.1 10.9 16.8 120.5 24.9 45.3 63.2 35.7 253.6 34.7 11.0 5.0 110.4 0.0 23.1 22.1 63.1 48.4 112.4 21.2 3.7 163.9 7.2 43.1 23.9 16.4 28.8 12.5 2.2 102.4 25.0 1.2 26.4 18.5 69.8 31.7 265.3 0.9 26.3 38.9 32.5 10.6 1.1 11.2 12.9 212.3 35.9 69.1 31.3 19.1 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGAP23 KIAA1501 ENSG00000275832 "Rho GTPase activating protein 23" Q9P227 17 38419280-38512385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.4;Hepatic stellate cells: 46.1;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 296.7;RT4: 115.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019818, HPA047291" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" Cytosol "HPA019818: AB_1844993, HPA047291: AB_2680012" "unprognostic (3.35e-1)" "unprognostic (5.11e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (6.87e-5)" "unprognostic (9.53e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (5.56e-2)" "unprognostic (1.50e-3)" "prognostic unfavorable (3.24e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.38e-5)" "unprognostic (8.36e-2)" "unprognostic (5.83e-2)" "unprognostic (4.57e-2)" "unprognostic (2.25e-1)" 25.6 13.8 36.2 8.3 66.2 10.7 18.8 47.2 54.6 25.9 5.5 22.8 3.0 28.4 3.7 60.8 18.4 7.8 27.3 34.4 37.5 11.8 2.9 28.0 4.1 63.7 59.6 18.1 3.5 3.1 6.2 19.4 54.1 19.9 2.8 8.5 12.8 12.5 10.6 61.1 10.4 11.6 43.0 30.7 13.4 16.1 66.1 5.4 9.5 5.8 11.0 36.3 29.5 97.8 32.5 17.2 15.2 5.1 9.5 31.1 19.6 44.8 49.5 37.7 21.8 56.8 55.1 0.7 35.2 102.5 18.7 296.7 1.7 62.3 26.6 3.5 3.3 0.0 55.1 0.4 47.2 3.0 0.3 18.8 11.8 27.7 17.3 31.0 39.4 6.0 0.6 8.3 21.6 0.0 10.2 6.3 9.0 1.2 6.3 17.0 33.0 10.4 16.0 115.7 3.7 8.8 26.9 0.1 0.3 21.2 6.7 7.9 57.7 62.6 22.9 12.9 12.1 6.5 7.3 1.9 16.3 8.1 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 66.2 47.2 54.6 34.4 37.5 63.7 59.6 54.1 43.0 66.1 97.8 27.2 12.8 1.5 23.8 0.7 9.9 17.5 10.6 9.1 59.4 1.7 3.9 20.4 1.5 13.2 3.7 0.0 27.0 0.2 0.1 0.0 2.9 7.6 8.5 10.0 34.9 0.0 4.0 9.3 1.4 3.1 11.6 3.1 5.7 0.0 4.9 46.1 0.5 5.1 26.9 16.2 0.4 2.0 2.5 4.2 21.0 9.0 1.2 1.8 9.4 0.2 9.6 0.0 20.1 129.2 7.0 0.1 7.2 1.7 15.4 0.0 0.2 8.3 3.4 0.0 10.9 7.6 13.5 2.7 27.5 25.9 16.6 1.8 1.3 0.3 42.2 ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 440.8;Endothelial cells: 298.6;Prostatic glandular cells: 593.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A-431: 118.8;hTERT-HME1: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" 32.9 3.7 7.0 2.8 5.5 0.1 30.3 22.5 8.0 8.8 7.3 9.4 2.1 7.4 5.3 4.5 10.2 6.5 19.2 4.6 5.5 23.7 16.8 27.1 4.9 6.8 6.1 10.2 7.4 6.5 6.2 17.4 7.1 11.2 3.2 14.9 12.1 7.0 11.6 14.7 6.4 5.6 6.4 21.7 10.4 5.8 8.6 3.0 22.8 12.7 2.8 8.0 9.3 5.1 118.8 4.8 7.0 0.1 26.7 57.5 24.5 38.6 62.9 31.0 45.1 13.7 5.4 0.0 85.2 76.5 36.3 24.8 0.2 27.4 63.9 0.1 4.1 0.4 6.6 7.6 2.7 0.0 0.0 11.7 5.4 23.7 100.9 36.4 88.0 0.1 0.0 0.0 32.1 4.7 2.2 0.1 9.0 0.6 82.1 1.4 5.6 0.0 82.7 10.8 0.1 1.5 24.1 20.5 2.0 26.5 5.6 0.4 84.2 20.0 26.2 29.7 32.3 0.1 0.1 0.2 3.7 0.0 0.9 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 5.5 22.5 8.0 4.6 5.5 6.8 6.1 7.1 6.4 8.6 5.1 440.8 51.3 18.4 26.4 2.9 23.5 239.2 31.7 4.6 16.0 87.3 46.1 26.0 31.5 39.6 130.6 18.8 29.5 2.0 0.9 54.8 83.5 94.1 36.9 11.4 298.6 0.0 3.2 11.3 17.2 102.6 63.6 20.9 106.2 3.8 13.8 177.1 56.1 3.0 92.5 24.1 1.0 6.1 13.6 17.9 24.4 24.5 6.2 26.6 208.9 2.5 94.2 0.0 2.0 3.5 55.7 0.1 21.8 0.1 593.9 0.1 78.1 12.5 81.2 190.7 58.2 127.8 80.3 116.5 1.7 17.2 14.1 4.1 11.1 1.6 146.9 ARHGAP32 "GC-GAP, GRIT, KIAA0712, MGC1892, RICS" ENSG00000134909 "Rho GTPase activating protein 32" A7KAX9 11 128965060-129279324 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 240.6;Excitatory neurons: 403.4;Inhibitory neurons: 239.7;Oligodendrocyte precursor cells: 170.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 26.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 36.6;RT4: 39.5;SK-BR-3: 42.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038382, HPA038389, HPA061505" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center" "HPA038382: AB_2675984, HPA038389: AB_10670972, HPA061505: AB_2684544" "unprognostic (1.17e-1)" "unprognostic (3.58e-2)" "unprognostic (2.54e-2)" "unprognostic (1.82e-1)" "unprognostic (3.89e-2)" "unprognostic (5.64e-2)" "unprognostic (1.52e-1)" "unprognostic (5.97e-2)" "unprognostic (7.32e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (6.64e-4)" "unprognostic (1.47e-1)" "unprognostic (6.17e-3)" "unprognostic (1.17e-1)" "unprognostic (4.01e-1)" "unprognostic (5.80e-2)" "unprognostic (1.64e-2)" 4.7 7.5 2.6 3.4 8.2 2.1 10.3 0.0 26.6 11.9 0.0 14.1 21.1 8.1 9.0 26.3 13.3 7.6 4.3 15.1 0.0 7.0 5.0 5.8 1.6 0.0 0.0 10.9 15.2 10.7 6.1 8.6 0.0 6.4 15.8 33.5 15.8 4.2 7.6 20.1 20.6 5.9 0.0 3.0 12.0 10.7 0.0 10.5 3.8 4.3 6.9 9.4 17.1 5.1 12.2 6.4 19.7 0.1 6.3 6.3 14.2 4.5 6.3 2.8 3.4 14.9 24.7 0.1 6.7 8.7 14.1 27.2 9.0 11.4 5.4 0.0 3.1 0.2 3.4 5.6 3.1 0.0 0.0 6.1 14.4 2.7 16.3 6.2 3.5 10.2 0.6 0.2 4.9 9.5 10.2 0.2 5.4 36.6 6.8 24.9 5.9 2.5 3.0 39.5 19.3 7.9 6.8 42.3 8.0 7.5 21.9 3.9 6.6 9.9 5.2 5.9 8.9 0.3 0.0 0.1 4.3 27.4 6.4 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.7 0.1 0.3 0.1 0.1 2.6 8.2 0.0 26.6 15.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 5.3 6.4 16.8 240.6 3.4 18.2 12.7 29.1 16.5 31.6 36.5 17.1 4.3 14.3 46.6 11.0 123.0 23.1 4.8 48.7 1.9 8.3 19.0 27.7 10.0 5.6 40.7 2.5 403.4 27.2 4.2 14.1 35.2 25.4 1.3 9.8 5.0 16.2 6.5 18.5 239.7 61.9 20.3 4.1 4.2 12.3 6.8 5.7 16.0 103.0 2.9 113.6 0.0 170.9 95.0 24.5 44.2 13.2 1.5 22.7 52.7 9.9 61.6 37.9 19.7 19.4 9.5 8.6 9.6 55.4 31.1 28.5 2.0 4.0 54.0 59.5 ARHGAP33 "FLJ39019, SNX26, TCGAP" ENSG00000004777 "Rho GTPase activating protein 33" O14559 19 35774532-35788822 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.4;Cone photoreceptor cells: 25.0;Horizontal cells: 20.2;Oligodendrocytes: 22.7;Rod photoreceptor cells: 33.7;Spermatocytes: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 58.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030117, HPA030118" Supported Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Actin filaments, Cytosol" "HPA030117: AB_10599306, HPA030118: AB_10601238" "unprognostic (1.44e-3)" "unprognostic (3.40e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (2.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.61e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" "unprognostic (2.97e-3)" "unprognostic (2.40e-2)" "prognostic unfavorable (3.09e-8)" "unprognostic (5.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-2)" 7.7 8.7 24.3 4.2 28.8 20.5 10.9 14.3 39.1 20.4 8.2 11.2 4.0 13.9 1.3 8.1 17.1 2.8 6.9 30.0 21.0 10.1 5.6 6.8 5.8 19.9 16.5 26.9 11.9 4.2 33.6 1.6 18.0 12.5 1.3 9.9 7.4 3.3 3.4 9.8 9.2 2.0 15.2 11.1 10.4 39.6 19.5 11.7 18.0 1.3 2.2 9.4 13.7 22.1 9.0 5.6 15.5 11.7 0.6 1.5 1.2 7.2 0.9 2.7 1.9 2.3 6.6 5.2 2.6 2.1 2.3 2.4 1.9 2.0 1.0 16.4 3.6 7.6 8.6 2.1 0.7 2.7 58.1 2.2 0.4 2.1 0.8 2.2 1.6 20.4 3.7 22.1 2.4 6.8 18.8 7.4 3.5 3.4 2.5 25.4 2.5 2.5 1.2 1.4 15.4 9.4 3.2 5.7 1.1 1.9 8.3 7.5 3.1 11.0 10.6 5.8 8.5 19.5 4.0 5.2 4.0 8.9 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 28.8 14.3 39.1 30.0 21.0 19.9 16.5 18.0 15.2 19.5 22.1 2.7 0.0 1.1 7.8 1.0 1.7 1.0 1.0 4.6 27.4 4.8 4.7 2.3 2.8 2.7 1.8 25.0 0.7 5.1 1.4 0.0 0.4 11.4 6.1 4.8 1.6 3.5 6.5 12.1 0.7 1.0 3.5 3.6 2.5 5.1 7.3 1.1 1.5 1.2 20.2 11.3 2.3 2.0 0.8 1.9 8.9 4.1 0.7 0.0 1.9 0.2 7.3 0.0 19.1 22.7 0.7 0.6 3.0 2.2 0.6 0.3 0.2 4.2 33.7 0.0 4.6 3.1 22.2 6.2 4.2 1.7 0.4 3.6 7.2 2.8 0.6 ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "adrenal gland: 105.4;brain: 144.3;pituitary gland: 176.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Breast glandular cells: 2.7;Oligodendrocyte precursor cells: 1.0;Skeletal myocytes: 1.5" "Cancer enriched" "Detected in some" 21 "thyroid cancer: 62.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 161 "SH-SY5Y: 176.9" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: AB_1078891, HPA076209: " "unprognostic (2.92e-2)" "unprognostic (7.71e-9)" "unprognostic (2.19e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.31e-1)" 0.2 105.4 20.1 0.0 3.7 0.0 1.4 0.8 3.2 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 13.5 132.5 0.0 0.0 0.0 0.0 35.0 46.1 0.0 0.0 0.0 176.9 0.1 144.3 0.2 0.1 0.0 0.2 0.0 6.6 0.1 0.0 0.0 4.7 0.0 0.1 0.8 52.1 0.4 0.1 1.1 0.0 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 176.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 3.7 0.8 3.2 13.5 132.5 35.0 46.1 144.3 4.7 52.1 10.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ARHGAP39 "CrGAP, KIAA1688, Vilse" ENSG00000147799 "Rho GTPase activating protein 39" Q9C0H5 8 144529179-144605816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Endometrial ciliated cells: 31.4;Excitatory neurons: 41.7;Inhibitory neurons: 33.1;Oligodendrocytes: 30.8;Respiratory ciliated cells: 27.6;Rod photoreceptor cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044491 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Nucleoplasm, Microtubules, Cytokinetic bridge" "HPA044491: AB_10794775" "unprognostic (3.42e-2)" "unprognostic (2.65e-2)" "unprognostic (9.85e-2)" "unprognostic (4.17e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-7)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (2.02e-1)" "unprognostic (6.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (9.97e-2)" 1.6 3.9 4.3 0.8 5.2 0.0 3.4 2.3 9.4 4.9 1.2 4.5 1.7 2.8 0.8 5.0 8.2 0.7 1.9 8.5 2.3 4.9 1.6 2.7 0.3 8.4 5.9 2.6 5.2 1.3 9.9 0.7 5.5 4.2 0.6 3.1 3.5 1.4 0.7 5.2 2.7 0.5 4.7 1.3 2.0 21.8 3.5 0.7 7.5 0.1 0.1 1.9 3.1 9.5 8.3 8.1 3.8 5.8 0.7 0.6 7.2 2.1 0.7 2.6 1.6 5.2 4.8 0.8 5.4 0.8 2.7 7.0 1.8 2.0 0.5 0.0 7.2 0.1 5.8 3.4 1.3 0.0 0.8 0.5 3.2 3.3 1.4 1.3 0.8 0.4 7.7 0.0 1.1 13.4 4.6 0.0 4.0 3.4 11.4 4.3 3.0 3.2 2.1 4.1 10.9 7.7 6.2 2.1 3.8 1.4 9.0 1.2 2.0 1.9 0.1 6.6 4.5 0.0 0.1 0.3 3.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 2.3 9.4 8.5 2.3 8.4 5.9 5.5 4.7 3.5 9.5 0.8 3.2 2.3 34.3 0.6 3.7 0.6 1.9 2.2 7.2 5.0 3.3 1.6 0.0 2.8 3.7 20.9 0.6 0.1 7.5 0.0 2.4 3.9 31.4 2.8 1.1 0.0 0.0 41.7 2.5 0.9 1.2 1.1 6.0 0.0 6.0 0.7 1.4 0.5 3.3 33.1 4.2 4.1 0.0 0.4 3.1 2.1 0.2 5.4 1.0 0.0 3.6 0.0 15.6 30.8 1.4 7.9 8.2 0.0 1.0 3.3 1.5 27.6 24.5 6.6 2.5 2.1 8.5 11.2 2.1 3.0 0.5 0.3 3.1 5.2 0.7 ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601934-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "breast: 32.4;epididymis: 35.7;esophagus: 28.7;skin 1: 45.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.7;Breast myoepithelial cells: 8.6;Club cells: 4.3;Collecting duct cells: 3.7;Early spermatids: 7.2;Late spermatids: 4.3;Respiratory ciliated cells: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.3;HBEC3-KT: 13.6;RPTEC TERT1: 11.7;SK-BR-3: 12.7;T-47d: 15.4" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: AB_10962149, HPA042840: AB_10963929" "unprognostic (9.89e-3)" "unprognostic (2.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-3)" "unprognostic (1.69e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (5.63e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (2.89e-4)" "unprognostic (2.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" 0.1 0.0 0.3 0.0 1.3 0.0 32.4 0.1 0.6 3.2 0.2 0.0 1.7 0.7 35.7 28.7 0.1 0.1 0.0 0.2 0.3 5.6 0.1 0.8 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 0.8 4.6 0.0 0.0 3.6 7.9 0.4 45.3 0.0 0.0 0.2 0.0 4.6 2.7 0.6 0.0 0.9 0.0 3.7 3.2 7.4 0.2 4.5 0.0 0.0 0.0 0.0 0.0 8.3 0.1 0.0 0.0 0.1 0.2 0.9 0.0 3.6 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 12.7 0.0 1.6 15.4 0.5 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.6 0.2 0.3 0.3 1.8 0.8 0.2 0.6 0.2 0.1 0.0 1.5 0.7 0.0 0.3 0.0 1.8 0.0 0.0 14.7 8.6 0.1 0.0 4.3 3.7 0.0 0.0 0.2 0.0 0.0 0.0 7.2 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.4 3.4 0.0 0.0 0.0 0.3 0.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 ARHGEF10L "FLJ10521, KIAA1626" ENSG00000074964 "Rho guanine nucleotide exchange factor 10 like" Q9HCE6 1 17539698-17697874 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 41 "classical monocyte: 18.8;intermediate monocyte: 18.0;myeloid DC: 13.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 48 "dendritic cells: 13.4;monocytes: 18.8" "Cell line enhanced" "Detected in many" "Hep G2: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026426, HPA026440, HPA028115" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA026426: AB_10599487, HPA026440: AB_10599422, HPA028115: AB_10602285" "unprognostic (4.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "prognostic favorable (8.13e-5)" "unprognostic (3.61e-2)" "unprognostic (7.90e-2)" "unprognostic (2.10e-2)" "unprognostic (1.75e-3)" "unprognostic (1.94e-3)" "unprognostic (5.83e-2)" "prognostic favorable (5.65e-4)" "unprognostic (4.11e-2)" "unprognostic (1.66e-1)" "unprognostic (8.17e-2)" "unprognostic (5.21e-3)" 22.2 10.5 11.9 11.4 10.9 1.7 16.5 38.7 11.4 24.2 13.8 29.4 15.9 16.2 4.6 28.1 16.0 11.9 30.2 10.3 12.2 32.5 87.5 13.0 4.5 19.4 18.5 10.4 43.9 17.0 7.9 5.9 19.4 18.4 12.9 4.0 25.9 19.5 66.2 40.9 21.7 8.7 10.9 9.7 20.8 3.7 17.7 1.6 18.0 35.5 4.3 24.6 21.7 9.3 8.0 9.1 11.3 3.9 19.1 6.3 7.6 5.4 10.6 6.3 5.3 9.5 23.6 0.0 9.8 10.2 8.8 6.0 1.6 2.9 1.2 0.2 2.9 0.0 9.5 26.9 4.2 0.0 0.0 8.5 5.5 3.9 1.1 12.7 1.2 0.0 0.0 0.2 17.8 7.7 0.0 0.2 4.9 12.2 0.0 0.0 4.5 3.0 13.4 16.4 16.5 12.2 4.2 2.9 12.3 3.2 11.0 9.5 0.0 5.5 6.5 6.5 2.3 0.0 2.5 0.0 8.5 0.2 3.0 0.0 18.8 0.0 0.0 18.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 7.6 11.9 10.9 38.7 11.4 10.3 12.2 19.4 18.5 19.4 10.9 17.7 9.3 1.3 3.2 7.4 82.6 1.0 5.7 5.3 7.2 5.2 16.1 13.7 12.3 36.4 20.0 13.9 31.3 2.1 0.7 0.1 41.6 9.8 19.8 15.9 3.4 4.2 2.1 37.8 2.7 16.7 20.3 0.6 8.5 17.9 6.5 0.0 3.9 2.5 43.7 26.0 10.1 23.8 45.5 8.2 8.6 26.4 8.9 5.0 18.6 3.6 19.7 9.6 14.6 0.0 24.6 7.1 11.7 24.9 6.8 0.2 5.9 13.6 18.3 9.4 5.4 13.1 10.8 18.3 11.9 1.6 8.0 8.7 1.0 0.6 0.3 46.1 12.1 ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" 25.6 30.6 27.2 14.3 26.9 11.4 31.9 26.8 32.1 32.9 26.4 27.6 25.0 27.8 25.4 27.6 29.3 28.4 40.3 30.9 23.0 67.4 66.4 36.7 11.9 17.8 25.6 25.2 26.1 68.4 14.6 42.9 17.3 26.5 29.1 47.7 25.0 30.9 32.2 49.5 25.5 30.3 20.1 21.5 32.2 9.7 35.9 13.5 51.5 31.8 18.7 28.7 22.0 19.3 38.1 31.6 41.9 39.8 55.0 54.5 16.7 43.8 49.8 26.1 33.1 37.5 27.2 3.2 51.7 79.8 46.6 27.5 54.1 56.0 51.3 31.1 25.8 61.8 34.0 29.2 49.2 0.1 43.7 52.4 39.7 57.8 63.8 58.0 80.7 32.7 52.4 122.5 67.0 26.6 0.1 0.1 11.4 49.3 26.1 13.4 47.4 11.9 65.1 66.1 30.0 36.4 61.5 51.0 16.2 25.0 43.1 5.1 80.1 57.2 24.2 37.6 32.4 35.1 15.4 20.2 23.6 7.9 44.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 27.2 26.9 26.8 32.1 30.9 23.0 17.8 25.6 17.3 20.1 35.9 19.3 86.2 73.7 88.4 274.9 8.6 90.5 69.1 47.2 42.1 134.6 55.1 26.9 87.6 68.6 57.8 97.5 185.6 16.7 11.5 59.7 35.2 45.6 6.4 61.4 55.7 94.0 37.8 69.7 239.0 50.9 10.4 44.0 34.7 140.3 11.4 44.9 85.6 118.3 7.3 90.9 192.4 39.6 18.3 31.2 25.6 14.8 29.8 18.2 51.6 118.0 8.7 41.0 13.4 143.2 55.0 53.5 52.1 33.4 9.3 85.6 48.1 76.3 48.7 80.9 26.3 58.4 60.3 16.3 13.8 55.3 85.1 28.7 16.1 43.1 41.3 99.1 ARHGEF26 "DKFZP434D146, SGEF" ENSG00000114790 "Rho guanine nucleotide exchange factor 26" Q96DR7 3 154121003-154257827 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 339.7;Astrocytes: 248.8" "Cancer enhanced" "Detected in all" "prostate cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017722, HPA049195" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017722: AB_1856800, HPA049195: AB_2680671" "unprognostic (1.41e-1)" "unprognostic (1.43e-3)" "unprognostic (3.55e-1)" "unprognostic (7.99e-3)" "unprognostic (2.82e-1)" "unprognostic (9.42e-3)" "prognostic favorable (9.74e-4)" "unprognostic (7.06e-2)" "unprognostic (1.16e-1)" "unprognostic (6.01e-5)" "unprognostic (1.44e-3)" "unprognostic (4.36e-2)" "unprognostic (2.22e-1)" "unprognostic (5.53e-3)" "unprognostic (3.11e-1)" "unprognostic (1.07e-1)" "unprognostic (5.24e-3)" 8.0 2.1 5.8 1.8 5.7 0.3 6.0 4.1 5.3 5.0 7.7 18.3 7.3 4.3 1.2 7.4 6.2 5.5 3.2 4.6 5.0 1.7 15.5 16.3 0.3 5.9 7.3 3.9 6.0 9.9 1.7 3.4 5.8 3.4 2.6 7.1 3.1 4.8 0.4 6.2 6.6 7.1 5.4 0.8 8.7 5.1 6.1 0.8 3.1 1.4 0.9 5.1 6.4 4.8 8.5 3.7 10.6 6.8 5.1 1.4 0.3 0.3 0.0 3.1 4.3 6.5 0.8 5.0 0.5 0.6 4.9 8.9 6.7 4.4 3.9 0.0 8.8 0.1 2.6 1.5 4.7 1.6 0.2 1.3 0.4 4.0 0.5 1.8 0.6 5.4 0.0 0.0 2.0 8.1 2.0 0.1 6.7 2.4 3.0 0.0 12.9 0.0 0.7 4.1 3.2 1.1 1.7 14.4 1.5 4.6 10.1 0.5 0.0 1.1 5.3 0.1 26.6 4.5 0.7 0.0 2.5 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.7 4.1 5.3 4.6 5.0 5.9 7.3 5.8 5.4 6.1 4.8 5.0 339.7 26.8 248.8 1.7 19.5 9.0 2.7 17.6 11.6 54.2 6.6 1.8 20.0 10.8 3.7 4.2 1.8 4.3 1.5 0.0 2.2 11.9 4.7 4.5 4.3 0.0 2.7 4.2 2.5 1.1 12.0 14.3 2.1 5.1 3.6 8.6 60.8 0.6 5.0 10.1 7.9 6.1 2.5 3.4 3.4 10.5 1.3 3.6 7.5 2.7 58.1 12.3 41.7 5.1 2.0 6.9 18.8 0.7 7.5 21.4 0.1 14.9 47.8 0.0 14.1 3.7 4.7 37.0 11.7 23.7 6.2 4.7 2.5 8.1 5.7 ARHGEF28 "p190RhoGEF, RGNEF, RIP2" ENSG00000214944 "Rho guanine nucleotide exchange factor 28" Q8N1W1 5 73626158-73941993 "Predicted intracellular proteins" Differentiation "Guanine-nucleotide releasing factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 31.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 73.1;Granulosa cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 97.8;LHCN-M2: 92.2;TIME: 59.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037602 Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytosol" "Plasma membrane" "HPA037602: AB_10672282" "unprognostic (1.97e-1)" "prognostic favorable (5.31e-4)" "unprognostic (7.66e-2)" "unprognostic (1.53e-1)" "unprognostic (3.33e-3)" "unprognostic (3.18e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (5.37e-1)" "unprognostic (3.63e-1)" "unprognostic (2.62e-1)" "unprognostic (3.04e-1)" "prognostic favorable (1.91e-6)" "unprognostic (1.07e-1)" "unprognostic (1.55e-2)" "unprognostic (1.62e-2)" "prognostic favorable (8.98e-4)" 4.8 23.9 4.5 1.1 4.7 0.0 7.5 0.4 5.1 3.9 0.0 3.3 3.2 4.1 2.5 6.4 9.8 5.3 1.9 5.0 4.3 31.5 6.4 7.3 0.4 1.6 2.0 19.0 20.7 1.2 6.0 0.5 3.2 5.0 3.7 6.0 19.2 3.6 0.9 14.8 2.5 3.5 1.4 2.8 21.8 1.5 3.2 4.0 13.6 0.9 2.9 3.7 6.6 2.8 30.1 21.0 0.1 2.6 2.6 3.6 0.0 10.8 21.5 13.5 13.3 6.3 12.8 0.1 22.5 3.7 30.4 10.0 1.4 17.4 20.2 0.2 3.1 0.6 3.3 27.2 20.9 0.0 0.0 3.3 7.0 21.0 97.8 25.2 44.4 0.6 0.0 0.0 92.2 2.8 0.0 0.0 0.2 7.9 8.5 0.0 5.5 3.7 36.4 18.0 2.0 3.9 5.3 0.8 0.6 0.0 4.6 0.1 59.8 6.6 9.2 0.5 10.3 1.1 0.0 0.2 10.1 1.4 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.5 4.7 0.4 5.1 5.0 4.3 1.6 2.0 3.2 1.4 3.2 2.8 9.1 28.9 16.4 3.9 0.2 25.7 14.1 14.1 40.5 4.9 7.5 11.0 2.0 24.3 15.5 31.3 0.0 0.3 2.1 3.7 15.6 13.0 9.6 32.7 1.7 12.8 11.4 2.7 73.1 11.3 0.3 3.1 35.7 12.6 1.3 83.2 2.2 7.3 0.3 13.5 34.5 10.7 40.7 0.3 0.9 2.6 10.2 3.3 1.8 32.8 0.6 26.8 1.0 34.7 15.2 26.3 4.6 5.7 1.2 16.0 3.9 26.7 50.4 1.6 6.6 0.5 7.0 1.0 1.3 20.4 25.6 0.1 1.2 32.3 6.7 17.3 ARHGEF33 ENSG00000214694 "Rho guanine nucleotide exchange factor 33" A8MVX0 2 38889875-38975454 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.8;Excitatory neurons: 15.2;Late spermatids: 26.8;Spermatocytes: 34.7;Spermatogonia: 35.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.6" "Group enriched" "Detected in some" 4 "BEWO: 5.6;HeLa: 2.6;SiHa: 7.2" "Region enriched" "Detected in many" 32 "cerebellum: 280.4" "Region enriched" "Detected in all" 6 "cerebellum: 23.1" "HPA034661, HPA041051" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA034661: AB_10669679, HPA041051: AB_2677274" "unprognostic (8.38e-2)" "unprognostic (7.05e-4)" "unprognostic (1.95e-1)" "unprognostic (4.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-1)" "unprognostic (3.66e-1)" "unprognostic (3.37e-1)" "unprognostic (5.82e-2)" "unprognostic (2.05e-3)" "unprognostic (4.99e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.42e-1)" "unprognostic (1.99e-1)" 0.4 2.1 4.9 0.6 5.2 0.0 0.9 22.6 5.8 1.5 4.4 1.0 0.1 1.5 2.6 0.4 1.4 0.8 0.5 4.9 4.1 0.9 0.2 0.7 0.3 4.1 5.4 3.5 0.4 0.7 3.4 0.5 4.0 0.9 0.3 4.0 0.5 0.7 0.3 0.8 0.4 0.5 3.1 0.3 0.5 5.7 7.2 0.1 1.1 0.0 0.2 0.7 0.7 5.0 0.2 0.0 0.2 0.1 0.1 0.1 5.6 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.1 2.6 0.1 0.4 0.2 0.1 0.5 0.6 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.3 0.2 7.2 0.3 0.0 0.6 0.0 0.2 0.4 0.1 0.9 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.2 3.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.9 5.2 22.6 5.8 4.9 4.1 4.1 5.4 4.0 3.1 7.2 5.0 0.4 0.0 1.5 7.8 0.1 0.0 0.1 0.0 0.6 2.5 0.3 0.6 0.8 1.5 0.6 0.0 0.0 1.1 0.0 0.1 0.0 0.1 34.8 1.8 1.2 0.4 0.0 2.7 15.2 0.0 1.9 1.2 0.0 0.2 0.0 1.4 0.0 0.2 1.0 0.0 11.4 0.4 0.0 0.0 0.0 26.8 1.2 0.2 0.0 1.9 0.1 3.6 0.0 5.5 3.4 0.0 0.0 3.4 0.0 0.1 0.0 0.4 3.9 2.9 0.0 0.3 1.5 34.7 35.6 0.1 0.1 0.5 0.0 2.0 0.1 0.2 ARHGEF5 "GEF5, P60, TIM, TIM1" ENSG00000050327 "Rho guanine nucleotide exchange factor 5" Q12774 7 144355288-144380632 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 47.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.7;Glandular and luminal cells: 47.4;Paneth cells: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 29.4;CAPAN-2: 21.9;HaCaT: 16.7;hTCEpi: 18.0;RPTEC TERT1: 17.5;WM-115: 17.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA020980, HPA029504, HPA044188, HPA045619, HPA045699" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA020980: AB_1845007, HPA029504: AB_10602231, HPA044188: AB_2678850, HPA045619: AB_2679393, HPA045699: AB_2679423" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-2)" "unprognostic (1.94e-1)" "unprognostic (9.45e-2)" "unprognostic (2.69e-2)" "unprognostic (9.95e-3)" "unprognostic (9.21e-2)" "unprognostic (1.05e-2)" "unprognostic (2.27e-1)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.28e-7)" "unprognostic (4.67e-2)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "unprognostic (7.76e-2)" 5.1 2.6 1.8 1.6 2.4 2.4 12.3 1.5 1.7 11.5 5.7 16.4 10.1 3.4 6.9 36.6 4.7 4.7 3.5 0.9 1.8 20.9 14.4 8.4 2.2 2.1 2.7 5.6 19.0 7.3 9.5 3.2 1.8 14.7 5.6 1.8 18.1 2.0 0.7 47.1 13.1 1.2 1.3 3.8 13.8 2.0 2.0 1.8 24.0 0.2 3.1 5.3 17.6 1.4 29.4 3.3 0.0 0.0 0.0 0.0 8.7 3.8 2.3 1.5 1.9 11.5 21.9 0.1 10.3 0.9 0.3 16.7 0.0 10.6 1.5 0.1 3.8 0.0 4.2 0.8 3.1 0.0 0.0 5.5 18.0 0.7 9.9 4.8 0.1 0.0 0.0 0.0 1.5 9.7 0.1 0.0 4.5 7.9 5.2 1.1 0.0 0.4 17.5 1.3 0.1 0.1 11.5 13.4 5.1 2.3 6.8 0.3 0.2 0.5 0.8 0.0 0.1 0.0 0.1 0.1 0.6 0.0 17.7 0.0 0.0 0.0 0.3 0.0 0.4 0.8 0.8 0.7 0.0 0.9 0.9 0.2 0.3 0.0 0.0 0.0 1.5 0.1 1.8 2.4 1.5 1.7 0.9 1.8 2.1 2.7 1.8 1.3 2.0 1.4 3.0 6.4 14.8 0.3 2.3 18.5 37.3 9.4 26.2 0.0 17.5 18.7 1.4 11.5 12.1 22.0 4.2 11.8 1.4 61.7 5.9 14.8 2.3 28.9 5.5 1.6 9.6 2.7 0.0 16.5 15.2 3.6 37.2 47.4 0.0 4.0 1.8 7.5 1.8 0.0 0.0 24.0 6.1 0.3 1.9 0.6 1.5 1.2 5.4 0.0 0.0 2.7 0.0 0.5 0.1 27.7 53.7 1.5 3.1 14.3 42.0 5.4 13.5 3.1 0.0 1.1 1.8 0.7 1.5 28.7 16.8 14.2 2.5 1.1 23.5 33.6 ARID4A "RBBP1, RBP-1, RBP1" ENSG00000032219 "AT-rich interaction domain 4A" P29374 14 58298504-58373887 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048899 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "HPA048899: " "unprognostic (1.57e-1)" "unprognostic (9.39e-2)" "unprognostic (5.17e-2)" "unprognostic (2.69e-1)" "unprognostic (3.70e-2)" "prognostic favorable (1.91e-4)" "unprognostic (2.71e-1)" "prognostic favorable (7.82e-4)" "unprognostic (2.08e-2)" "unprognostic (6.92e-2)" "unprognostic (3.27e-1)" "unprognostic (3.72e-2)" "unprognostic (9.32e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (4.11e-2)" "unprognostic (3.52e-2)" 9.8 6.9 8.6 11.1 9.2 34.7 9.1 14.8 10.0 8.6 8.9 7.7 8.8 9.5 6.8 7.4 6.8 9.0 8.7 8.0 11.7 9.4 18.7 10.3 14.9 7.9 7.7 12.5 7.4 9.8 5.4 9.8 7.6 8.6 8.8 14.0 6.7 7.6 5.4 8.7 9.1 8.2 6.8 14.0 8.9 6.9 12.3 14.5 10.6 6.3 11.2 8.4 7.5 10.7 8.5 7.0 19.2 9.5 9.3 11.2 9.7 9.9 8.4 6.6 10.4 8.3 13.1 20.4 10.3 8.4 6.3 9.6 8.6 4.8 9.6 14.3 5.5 9.2 8.2 8.0 5.6 19.7 12.8 8.4 5.2 6.4 6.6 10.5 10.6 11.6 10.7 16.3 7.1 11.5 14.3 17.7 3.8 8.2 8.7 14.5 16.6 6.1 7.1 14.9 16.5 14.3 16.9 8.4 12.0 9.4 14.3 17.8 15.3 11.2 8.7 9.1 4.6 5.3 4.2 18.3 6.7 12.3 5.8 65.8 19.5 59.1 20.6 20.1 23.3 31.5 25.3 22.1 14.9 42.3 27.0 26.5 109.4 29.1 40.8 19.8 19.8 10.1 8.6 9.2 14.8 10.0 8.0 11.7 7.9 7.7 7.6 6.8 12.3 10.7 57.7 83.3 100.9 68.9 73.5 38.4 21.2 22.1 64.3 111.0 29.5 35.8 55.0 24.3 32.3 27.6 52.1 19.9 74.0 33.0 19.6 23.3 18.2 40.5 37.6 47.1 22.8 45.8 94.2 21.7 21.3 40.1 26.0 52.6 65.2 39.9 37.5 41.9 34.7 112.7 78.6 35.5 20.3 47.7 49.5 8.8 36.4 59.3 26.6 63.7 75.8 63.9 49.4 86.5 91.4 24.9 38.6 36.1 55.1 20.9 43.4 14.9 11.2 64.2 19.7 40.0 43.0 38.6 33.8 55.4 33.4 20.4 77.0 34.1 32.9 17.7 ARID4B "BCAA, BRCAA1, RBP1L1, SAP180" ENSG00000054267 "AT-rich interaction domain 4B" Q4LE39 1 235131634-235328219 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 486.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027205, HPA027333" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" Nucleoplasm "HPA027205: , HPA027333: AB_1845013" "unprognostic (2.62e-1)" "unprognostic (2.38e-1)" "unprognostic (1.67e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-3)" "unprognostic (7.75e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-2)" "unprognostic (1.30e-2)" "unprognostic (1.03e-1)" "unprognostic (5.69e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (1.42e-2)" "unprognostic (1.25e-1)" "unprognostic (3.52e-2)" "unprognostic (8.84e-3)" 11.3 10.9 9.6 14.1 11.2 33.0 13.5 12.8 13.0 15.0 7.8 10.2 8.1 15.9 14.4 9.8 10.9 13.2 7.4 8.4 9.5 10.6 11.9 12.0 21.0 10.4 10.5 17.2 11.4 13.6 10.9 12.7 10.8 14.3 9.1 14.6 11.5 10.8 9.0 9.0 10.3 10.2 9.9 18.4 13.2 17.1 9.6 21.4 16.9 9.8 17.0 12.9 10.6 13.0 15.8 10.5 18.0 16.5 15.3 15.5 17.5 17.6 15.1 11.3 10.9 12.2 16.9 18.1 19.9 12.0 8.7 13.4 16.4 7.4 17.8 23.5 17.3 14.7 14.7 10.9 11.9 15.8 21.0 10.8 10.4 13.5 12.7 16.1 18.2 11.4 19.3 25.4 11.9 7.5 21.9 15.3 18.9 12.1 8.2 9.4 13.4 15.3 14.1 13.2 15.9 22.4 22.1 20.3 18.3 6.2 19.1 27.4 21.6 14.4 11.5 18.2 17.7 25.1 22.1 18.2 9.8 11.9 19.4 61.7 13.7 41.1 29.9 15.0 27.5 32.2 31.6 26.0 13.8 34.0 31.2 26.7 72.5 33.8 25.6 23.6 28.3 12.6 9.6 11.2 12.8 13.0 8.4 9.5 10.4 10.5 10.8 9.9 9.6 13.0 156.8 102.5 106.8 107.7 150.1 124.3 83.8 61.2 103.0 125.5 86.2 78.5 77.4 47.1 91.7 31.3 120.9 64.0 218.9 47.9 19.6 76.4 334.7 119.3 127.9 128.9 90.1 45.2 157.0 47.9 70.2 101.6 59.1 169.2 110.1 78.0 67.8 27.6 44.4 112.7 158.4 53.2 65.1 61.2 127.6 486.5 101.2 97.3 83.6 107.7 122.8 67.7 204.9 144.8 304.2 68.6 57.3 77.5 104.1 108.7 48.3 20.6 82.3 150.7 46.0 130.2 121.4 236.7 161.9 66.5 106.4 156.7 209.8 84.8 44.7 149.6 ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901684-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 968.2;Syncytiotrophoblasts: 920.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 115.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: AB_1845015" "unprognostic (3.31e-1)" "unprognostic (1.99e-2)" "unprognostic (2.94e-2)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (5.60e-2)" "unprognostic (1.50e-2)" "unprognostic (4.90e-2)" "unprognostic (3.90e-1)" "unprognostic (6.03e-2)" "unprognostic (1.97e-1)" "unprognostic (5.75e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" 50.0 8.1 2.9 21.2 5.8 6.9 34.3 3.2 11.3 37.2 20.7 17.5 10.2 39.0 4.6 20.2 20.6 39.3 18.3 4.4 1.6 21.4 8.3 18.3 18.8 7.8 6.9 17.5 6.2 13.3 10.0 21.0 11.4 18.3 11.7 4.1 15.8 10.2 87.2 18.1 14.2 42.5 0.9 16.9 11.5 6.9 9.0 13.1 7.8 11.9 16.7 30.9 19.6 9.7 2.2 0.9 6.0 14.7 13.0 34.0 1.2 42.9 115.2 29.9 23.3 52.7 2.3 3.9 10.1 41.4 4.3 14.3 20.6 6.5 36.0 13.7 6.1 2.1 10.4 13.5 23.9 0.6 25.2 43.3 3.4 17.6 20.2 26.2 3.9 7.5 1.9 5.7 9.9 7.7 14.4 1.1 1.1 10.2 13.5 17.7 9.8 1.1 20.1 23.9 3.3 4.4 19.2 10.6 12.8 13.1 8.7 0.7 3.3 16.5 22.0 25.1 10.9 0.4 0.0 11.4 14.3 0.8 5.4 9.6 1.2 0.8 13.3 2.8 1.8 37.5 19.7 11.8 2.2 41.2 12.8 8.4 2.2 12.3 8.2 1.0 30.9 5.4 2.9 5.8 3.2 11.3 4.4 1.6 7.8 6.9 11.4 0.9 9.0 9.7 86.2 131.4 70.7 54.5 199.8 968.2 453.9 111.3 105.9 54.4 112.8 96.6 72.8 27.1 96.3 51.5 0.0 187.8 89.1 7.5 99.7 56.1 31.7 164.7 231.0 134.1 36.4 5.2 167.8 14.6 150.7 343.6 21.4 457.7 24.6 37.6 119.2 7.4 51.0 74.0 181.9 18.7 22.4 44.1 162.4 20.1 151.6 43.6 138.7 34.7 39.0 17.2 58.7 74.4 155.8 41.1 25.2 60.5 234.5 193.7 5.4 304.8 38.4 3.6 131.5 496.3 463.9 8.2 5.8 65.7 477.8 920.4 178.2 24.3 41.7 233.9 ARL13A ARL13 ENSG00000174225 "ADP ribosylation factor like GTPase 13A" Q5H913 X 100969708-100990831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.1" "Group enriched" "Detected in some" 29 "Early spermatids: 69.8;Late spermatids: 55.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037377, HPA037378" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "Actin filaments, Cytosol" "HPA037377: AB_2675442, HPA037378: AB_10670932" "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.08e-2)" "unprognostic (1.93e-1)" "unprognostic (9.06e-3)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.51e-2)" "unprognostic (4.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (9.37e-4)" "unprognostic (2.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.1 5.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.6 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 55.5 0.6 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARL14EP "ARF7EP, C11orf46, FLJ38968" ENSG00000152219 "ADP ribosylation factor like GTPase 14 effector protein" Q8N8R7 11 30323104-30338223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039634, HPA048127" Approved Supported "Nucleoplasm,Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Focal adhesion sites, Cytosol" Nucleoplasm "HPA039634: AB_2676606, HPA048127: AB_2680277" "prognostic favorable (2.50e-5)" "unprognostic (8.93e-2)" "unprognostic (6.19e-3)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (5.26e-4)" "unprognostic (2.50e-2)" "unprognostic (6.50e-3)" "unprognostic (5.76e-2)" "unprognostic (8.86e-2)" "unprognostic (1.04e-1)" "unprognostic (8.57e-3)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (4.50e-2)" "prognostic favorable (7.49e-4)" 13.9 22.5 13.5 13.2 15.6 8.0 20.0 15.9 17.3 17.0 14.9 11.8 9.5 18.9 23.2 11.6 16.4 13.1 22.9 15.7 14.2 17.4 19.7 10.9 22.5 12.4 13.3 20.5 12.9 26.1 12.0 11.5 12.1 19.7 10.8 15.9 19.1 19.9 20.6 12.6 9.7 14.5 13.9 20.8 15.7 14.6 13.3 15.6 24.7 20.8 21.4 14.5 8.1 13.8 10.8 15.4 16.9 14.8 27.1 29.2 8.5 20.8 26.0 18.4 20.2 8.5 4.1 43.8 13.9 15.0 20.5 17.8 24.8 17.5 25.9 35.2 30.7 13.3 12.0 15.0 42.6 24.0 14.7 30.5 34.7 8.7 32.8 26.7 20.6 17.9 21.4 23.2 32.5 10.4 21.9 19.6 19.6 24.1 21.3 18.8 41.2 18.0 24.7 14.8 19.2 20.4 16.2 21.4 25.8 15.0 22.8 13.4 18.1 20.8 11.2 41.7 20.1 36.0 21.9 28.5 20.0 14.8 20.4 12.7 19.2 6.4 23.3 20.0 55.5 35.9 28.2 25.9 26.3 28.9 25.7 25.0 3.5 52.9 15.5 18.9 20.3 23.1 13.5 15.6 15.9 17.3 15.7 14.2 12.4 13.3 12.1 13.9 13.3 13.8 27.3 28.9 33.6 14.4 39.7 12.4 46.6 35.1 8.0 34.0 19.9 30.4 68.1 24.3 23.8 25.8 14.6 19.1 29.2 5.9 76.3 27.3 130.1 25.8 41.0 29.2 14.5 13.2 31.1 22.5 12.7 33.4 12.8 19.0 27.8 33.5 15.4 29.8 25.7 32.0 26.4 11.7 32.6 27.1 29.3 66.3 27.4 28.4 26.6 18.7 45.4 36.1 38.1 27.6 19.9 21.9 8.4 25.2 25.4 46.0 9.4 42.1 27.5 32.4 13.1 33.1 29.8 111.4 37.6 13.8 11.1 11.1 29.6 33.0 12.6 28.4 ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 441.6;Inhibitory neurons: 285.2;Microglial cells: 408.5;Oligodendrocyte precursor cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044604, HPA063820" Uncertain Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Plasma membrane, Cell Junctions" "HPA044604: AB_10960542, HPA063820: AB_2685131" "unprognostic (2.18e-1)" "unprognostic (4.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-3)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (6.56e-2)" "unprognostic (4.26e-3)" "unprognostic (3.86e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "unprognostic (9.15e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" 14.0 12.5 6.6 5.6 7.5 1.9 13.0 5.6 10.0 17.7 7.2 10.6 11.9 16.0 7.6 9.8 8.2 14.5 14.0 8.5 7.1 17.9 9.8 7.6 6.3 5.8 6.2 5.7 5.0 3.2 8.5 22.3 6.0 10.0 10.9 7.6 10.5 6.8 3.3 11.3 9.9 16.6 6.1 8.2 8.3 9.3 6.8 10.6 8.4 11.7 8.0 13.6 8.8 6.2 3.2 5.5 8.5 15.6 7.0 7.8 11.8 10.2 15.1 9.4 20.7 21.1 8.0 32.0 14.9 9.1 11.0 7.7 13.2 14.1 12.4 3.2 13.9 36.9 7.1 2.8 2.5 4.5 43.8 10.0 10.1 15.8 9.5 14.2 20.8 7.0 32.4 5.3 6.5 7.7 7.5 4.3 3.0 1.6 3.9 6.2 10.4 0.8 12.8 30.3 11.3 7.1 13.1 6.7 7.9 15.6 8.6 4.7 11.4 5.7 9.6 5.4 6.7 1.8 1.7 34.8 9.9 10.6 9.5 1.1 1.8 2.2 1.3 1.4 0.7 1.0 0.9 0.9 2.4 0.7 0.9 0.7 3.5 0.7 1.2 0.3 2.3 1.2 6.6 7.5 5.6 10.0 8.5 7.1 5.8 6.2 6.0 6.1 6.8 6.2 44.5 3.2 7.7 33.6 6.5 9.7 7.9 5.8 8.0 5.1 4.8 5.8 7.5 5.7 4.5 12.9 14.6 52.5 5.2 7.5 21.5 3.2 3.4 4.1 6.9 35.1 20.9 8.6 441.6 4.9 4.9 8.5 6.6 5.1 2.5 3.2 26.0 4.9 8.4 1.7 285.2 7.6 18.3 8.7 8.7 1.5 4.4 12.5 1.8 408.5 5.0 3.2 6.2 184.5 104.7 6.9 7.6 3.8 4.7 5.4 5.7 10.0 3.9 3.0 6.6 3.6 5.3 1.0 3.5 5.9 10.1 42.7 8.9 24.4 7.1 8.4 ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014160-65022184 "FDA approved drug targets, Predicted intracellular proteins" "Cell cycle" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 430.8;Late spermatids: 1125.1;Proximal tubular cells: 505.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Focal adhesion sites,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus, Focal adhesion sites, Cytosol" "HPA044610: AB_10964207" "unprognostic (9.23e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (1.61e-1)" "unprognostic (5.08e-2)" "unprognostic (1.07e-3)" "unprognostic (2.34e-1)" "unprognostic (9.85e-3)" "unprognostic (6.43e-2)" "unprognostic (6.87e-3)" "prognostic favorable (7.70e-4)" "unprognostic (2.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (1.24e-2)" 124.8 93.7 161.5 40.6 190.2 51.3 112.0 172.4 200.2 106.3 132.3 123.1 52.7 121.2 28.2 67.2 94.6 48.0 169.1 157.0 168.7 138.5 22.5 90.4 37.7 171.5 167.9 95.7 75.3 65.3 68.5 56.1 167.2 84.7 32.9 43.5 67.9 66.6 214.2 95.8 73.4 60.9 171.4 63.4 85.2 116.1 167.4 33.5 85.7 158.1 29.0 112.2 93.5 184.4 162.0 257.0 76.5 115.8 207.4 156.5 70.5 82.5 181.7 111.2 109.1 72.8 110.0 62.1 144.5 112.7 168.1 101.4 82.9 140.0 53.1 65.5 130.6 61.9 109.2 111.9 157.8 77.9 54.9 123.7 114.6 92.6 204.4 160.5 150.4 74.0 152.8 110.1 76.4 194.1 63.1 174.5 120.3 77.7 208.6 33.4 81.6 152.9 120.9 70.6 143.3 79.3 66.4 67.6 225.8 74.4 72.3 94.3 109.2 205.9 68.6 164.7 82.1 37.9 57.6 38.5 97.2 112.5 171.3 46.5 78.2 72.5 120.4 80.2 130.9 163.1 110.0 116.9 101.7 149.0 123.5 137.2 10.2 83.3 48.2 140.1 79.0 136.9 161.5 190.2 172.4 200.2 157.0 168.7 171.5 167.9 167.2 171.4 167.4 184.4 179.1 22.4 43.6 0.0 42.7 81.4 94.4 118.4 63.7 70.2 66.8 83.9 103.2 51.5 66.4 82.8 29.2 179.7 40.0 110.0 268.0 142.0 430.8 42.2 59.0 148.0 83.3 69.4 0.0 76.0 193.5 107.0 29.6 50.7 95.7 71.5 137.4 19.7 98.3 69.0 0.0 68.4 83.4 49.7 73.5 1125.1 71.7 49.5 177.9 0.0 100.6 208.4 55.6 0.0 0.0 68.3 115.7 71.1 16.5 79.9 162.4 505.5 47.0 48.9 65.7 74.2 109.7 126.5 79.4 56.3 82.8 107.3 40.0 65.7 98.0 75.9 ARMC5 FLJ13063 ENSG00000140691 "Armadillo repeat containing 5" Q96C12 16 31458080-31467166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041524, HPA063706" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA041524: AB_10796676, HPA063706: AB_2685098" "unprognostic (1.37e-1)" "unprognostic (1.68e-3)" "unprognostic (8.22e-3)" "unprognostic (9.96e-2)" "unprognostic (2.59e-1)" "unprognostic (2.94e-3)" "unprognostic (4.09e-2)" "unprognostic (6.14e-3)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (1.97e-6)" "unprognostic (4.70e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" 6.3 7.9 9.0 3.4 9.2 21.4 4.3 8.9 11.7 6.0 7.0 5.8 4.6 6.9 0.9 9.9 5.6 2.0 6.5 9.2 8.1 8.7 24.6 4.6 3.2 12.3 9.4 6.8 6.4 3.0 9.0 2.1 12.4 7.7 0.9 2.4 5.3 2.2 16.0 8.5 7.0 1.7 9.1 8.8 6.8 6.8 9.2 2.9 9.7 3.9 1.3 5.6 6.6 10.5 5.0 7.6 3.3 4.8 2.0 1.5 8.4 6.5 2.8 3.6 3.0 7.2 5.0 4.9 13.3 3.5 3.6 7.5 3.9 5.7 0.7 6.8 9.9 2.2 12.4 16.7 4.0 14.9 14.3 3.7 6.3 3.6 1.0 4.2 5.5 8.0 11.2 11.5 2.5 12.2 5.6 59.5 5.3 2.2 5.0 10.0 4.7 18.2 2.9 5.6 10.7 9.4 5.9 7.8 4.6 2.0 5.1 17.6 10.9 7.8 5.7 3.2 5.4 10.4 9.8 3.0 5.1 12.2 5.7 2.9 2.3 0.7 3.2 1.1 2.7 2.7 2.5 2.6 3.0 2.2 2.2 2.6 1.3 7.1 1.3 7.2 3.2 2.6 9.0 9.2 8.9 11.7 9.2 8.1 12.3 9.4 12.4 9.1 9.2 10.5 8.7 6.4 14.3 4.2 6.2 6.5 9.2 8.7 9.1 6.0 6.3 5.0 5.8 11.5 8.2 0.0 6.2 7.5 7.6 11.1 3.9 5.0 1.2 5.2 8.6 10.8 7.8 8.2 4.3 4.4 5.4 6.1 6.6 7.6 9.5 6.7 8.9 28.7 6.1 13.5 4.0 8.7 6.1 3.7 4.0 0.6 4.4 6.7 1.8 2.8 3.9 7.2 6.2 2.0 4.6 4.4 3.8 5.7 8.0 6.9 9.2 4.6 3.4 5.9 0.0 8.7 6.6 5.5 8.0 9.6 6.3 11.5 7.6 6.1 7.7 6.1 ARMC8 "DKFZP434A043, GID5, HSPC056, VID28" ENSG00000114098 "Armadillo repeat containing 8" Q8IUR7 3 138187248-138298384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036996, HPA044869" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Vesicles, Cytosol" "HPA036996: AB_10672786, HPA044869: AB_2679123" "unprognostic (2.04e-1)" "unprognostic (1.60e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (3.51e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (8.90e-5)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (7.48e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (3.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.06e-2)" "unprognostic (5.51e-2)" "unprognostic (1.18e-1)" 20.8 14.3 14.6 18.0 16.6 60.6 16.4 41.2 18.5 14.7 25.6 16.8 12.0 17.6 12.2 21.0 15.7 15.3 17.4 13.3 16.9 18.9 16.9 16.3 21.2 16.0 15.8 16.0 14.2 21.3 12.3 19.8 17.5 16.5 18.3 26.2 12.5 17.5 38.7 12.8 13.5 24.4 15.9 15.9 15.4 18.4 16.7 22.2 21.3 34.8 22.9 22.2 13.4 19.4 46.2 22.0 28.5 23.2 35.2 30.7 37.9 34.8 33.4 46.7 45.3 34.3 23.7 43.2 35.0 30.2 54.6 23.5 37.1 33.9 57.4 29.3 25.7 77.2 14.3 23.9 44.3 60.6 82.5 46.2 21.2 30.0 42.9 25.4 37.0 37.0 29.3 23.8 58.6 40.5 42.7 28.6 39.2 34.8 19.1 33.0 45.7 34.6 30.7 42.3 33.0 24.0 50.0 17.2 29.1 36.8 33.8 31.6 40.4 24.8 20.2 33.1 25.9 45.0 37.5 65.2 22.4 28.4 25.2 79.7 39.7 74.8 38.6 43.5 44.6 48.8 35.2 41.1 45.9 43.3 41.1 40.6 27.9 48.8 46.0 20.3 50.4 37.4 14.6 16.6 41.2 18.5 13.3 16.9 16.0 15.8 17.5 15.9 16.7 19.4 25.0 28.9 14.1 56.2 38.2 31.0 31.9 29.0 25.0 34.9 17.7 14.9 23.1 24.3 27.2 12.9 33.3 29.9 35.6 25.1 11.7 20.2 7.3 16.2 22.3 23.4 23.4 59.6 101.9 14.6 27.6 23.4 31.1 19.5 35.4 24.1 24.3 24.6 22.5 43.7 93.6 16.9 30.5 32.7 39.2 7.3 30.4 35.2 19.6 70.3 27.2 25.0 39.1 128.2 120.8 14.8 17.2 22.2 26.8 28.1 17.0 26.1 17.4 47.0 13.1 30.2 31.5 43.4 32.2 22.3 28.4 34.1 30.9 19.6 17.4 28.3 ARMCX1 "ALEX1, GASP7" ENSG00000126947 "Armadillo repeat containing X-linked 1" Q9P291 X 101550547-101554700 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 7.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 74.9;ASC TERT1: 66.9;BJ hTERT+ SV40 Large T+ RasG12V: 78.2;LHCN-M2: 70.7;RH-30: 87.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000268, HPA005685, CAB020695" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Cytosol" "CAB020695: , HPA000268: , HPA005685: AB_10600781" "unprognostic (2.31e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-3)" "unprognostic (2.13e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.32e-5)" "unprognostic (1.02e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-3)" "unprognostic (8.77e-2)" "unprognostic (2.12e-2)" "unprognostic (1.09e-2)" 24.4 34.0 16.8 8.8 18.4 3.1 21.9 14.9 21.9 32.3 18.2 31.4 7.0 30.4 21.2 11.4 25.2 17.5 32.8 18.0 19.5 13.7 4.0 16.5 5.5 16.2 17.9 48.3 12.8 16.9 25.9 14.9 18.8 24.3 7.6 12.0 14.1 23.0 27.7 10.9 12.0 21.2 15.6 14.1 14.8 5.9 17.7 6.3 16.4 25.5 3.4 23.2 21.7 17.9 2.1 0.6 16.0 0.0 74.9 66.9 0.2 25.5 49.7 31.4 78.2 0.0 0.4 0.0 21.3 39.3 34.2 2.1 0.0 3.7 17.7 0.1 0.0 14.9 5.1 0.0 39.6 0.0 0.2 56.5 4.8 23.8 0.0 25.9 19.2 0.0 0.3 0.3 70.7 1.0 0.0 0.1 23.1 0.0 0.2 0.0 87.8 0.1 21.6 0.0 15.8 13.1 0.0 0.3 45.9 4.4 2.5 11.0 25.6 18.9 10.0 55.5 0.3 0.0 0.3 0.0 18.6 0.0 12.1 0.0 3.3 0.4 0.0 3.1 0.5 0.0 0.4 0.3 7.7 0.2 1.1 2.7 0.1 1.8 0.9 4.0 0.8 1.6 16.8 18.4 14.9 21.9 18.0 19.5 16.2 17.9 18.8 15.6 17.7 17.9 27.6 25.6 7.4 8.5 0.7 33.1 22.9 5.0 18.2 32.2 19.1 17.4 59.7 7.2 4.1 23.9 6.2 1.6 3.7 0.6 13.7 21.1 0.3 10.4 23.2 29.9 5.4 4.2 9.5 7.1 2.6 53.2 9.2 11.2 24.1 20.0 20.7 0.8 27.9 21.9 11.8 2.2 2.0 9.5 33.4 2.0 47.2 17.5 58.7 4.7 5.7 36.0 0.0 11.1 8.4 5.6 0.1 44.4 0.4 20.6 0.6 13.6 3.6 13.9 46.0 60.6 39.9 1.6 0.7 3.8 21.7 2.6 2.3 35.6 2.5 7.5 ARMCX3 "ALEX3, GASP6" ENSG00000102401 "Armadillo repeat containing X-linked 3" Q9UH62 X 101622797-101627843 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000325, HPA000967, HPA001530" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA000325: AB_1078206, HPA000967: AB_1078208, HPA001530: AB_2666349" "unprognostic (1.67e-1)" "unprognostic (2.14e-1)" "unprognostic (5.23e-2)" "unprognostic (8.69e-3)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (9.72e-3)" "unprognostic (2.19e-2)" "unprognostic (4.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-2)" "prognostic favorable (1.55e-5)" "unprognostic (3.29e-2)" "unprognostic (3.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.55e-2)" 34.9 58.9 30.8 24.4 33.0 14.7 32.2 35.4 35.7 45.0 27.6 31.5 20.2 40.9 105.3 18.1 27.7 34.0 51.0 34.1 38.7 37.2 24.6 29.5 21.8 34.5 33.7 38.3 57.4 103.6 47.7 45.4 34.8 44.5 21.8 19.0 59.6 46.7 30.7 11.9 21.5 36.3 35.4 41.3 29.7 12.9 35.5 20.1 49.9 63.6 21.5 31.9 22.5 37.7 26.4 18.8 48.8 23.9 109.4 118.3 10.0 56.5 54.3 23.2 68.3 20.7 21.5 9.5 31.7 64.7 50.8 5.0 34.9 20.2 28.7 21.6 23.2 18.7 64.9 30.2 85.2 18.2 41.5 67.0 27.4 30.9 30.3 65.1 47.6 11.6 15.2 78.9 67.4 10.9 15.0 0.8 24.4 49.5 4.3 19.1 62.2 8.9 36.0 10.1 22.1 18.9 28.3 1.5 63.9 67.7 19.2 19.0 67.5 29.8 18.9 70.8 11.2 69.7 20.9 0.1 50.4 14.5 25.5 43.6 15.3 13.6 14.6 15.8 18.3 15.0 14.0 12.4 15.8 9.8 15.2 10.6 5.6 13.7 16.8 25.8 9.0 14.4 30.8 33.0 35.4 35.7 34.1 38.7 34.5 33.7 34.8 35.4 35.5 37.7 67.4 44.8 36.1 16.3 61.1 37.9 81.2 40.6 42.7 63.1 70.9 42.3 114.6 50.1 48.4 75.4 58.4 55.3 61.1 20.4 37.2 53.9 0.6 42.2 80.9 69.2 82.4 25.6 35.9 30.6 27.4 85.8 33.1 78.8 79.1 45.5 58.2 48.6 50.7 62.2 41.8 67.6 40.7 52.5 84.9 2.8 64.7 72.3 97.8 18.7 27.2 86.6 34.0 28.6 31.0 30.6 22.1 72.6 122.6 75.2 20.1 43.1 25.1 13.3 32.9 57.1 73.2 2.5 0.4 24.6 21.5 114.9 58.0 70.2 32.1 81.2 ARMCX5 "FLJ12969, GASP5" ENSG00000125962 "Armadillo repeat containing X-linked 5" Q6P1M9 X 102599168-102604159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 88.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000996 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Cytosol" "Plasma membrane" "HPA000996: AB_1078212" "unprognostic (7.71e-2)" "unprognostic (2.43e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (1.54e-1)" "unprognostic (5.05e-2)" "unprognostic (4.07e-2)" "prognostic favorable (6.58e-5)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (2.83e-1)" "unprognostic (3.28e-3)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (2.83e-1)" "unprognostic (5.24e-2)" 8.2 11.0 10.4 8.8 10.6 10.3 17.8 10.0 11.5 13.7 6.9 12.8 10.8 15.2 15.5 11.0 15.0 10.0 10.7 11.4 9.3 12.6 11.3 11.2 10.4 7.7 7.0 20.3 14.7 19.9 7.2 8.4 7.6 20.6 15.3 10.6 15.7 13.5 9.3 11.2 12.3 13.9 7.3 8.0 13.5 5.4 9.6 16.2 19.5 10.1 13.3 11.2 6.5 11.4 17.8 15.7 36.4 19.4 15.9 17.8 20.4 17.1 13.1 19.5 34.5 18.7 21.5 0.0 20.3 17.2 22.3 15.1 32.8 16.3 22.1 0.0 13.1 17.9 19.2 15.6 20.6 32.7 20.0 22.3 20.7 16.9 20.3 15.5 20.0 0.0 17.6 0.1 26.3 15.8 23.3 3.9 16.4 30.3 29.5 22.7 88.9 0.1 14.5 24.2 17.1 15.4 30.5 15.7 24.7 10.4 10.8 15.4 20.3 14.5 12.8 16.5 12.3 0.0 13.0 0.0 11.4 32.7 37.8 0.1 11.8 3.2 13.9 12.3 13.3 12.5 12.8 10.9 11.3 6.4 17.8 14.0 1.0 9.3 7.8 10.0 9.7 11.1 10.4 10.6 10.0 11.5 11.4 9.3 7.7 7.0 7.6 7.3 9.6 11.4 6.9 6.4 6.9 0.0 9.0 5.6 11.7 8.0 19.4 16.5 8.9 7.7 4.4 7.2 10.3 9.2 20.9 5.7 9.2 6.8 21.5 10.0 0.3 5.9 8.3 9.6 9.6 3.4 0.0 9.7 2.6 9.9 10.7 5.7 1.3 7.8 5.7 9.6 6.0 1.7 0.0 9.8 4.1 7.2 3.5 0.5 8.4 6.6 8.8 0.0 4.6 6.5 10.3 0.0 0.0 9.3 3.8 6.0 12.0 9.3 9.6 10.6 13.7 20.8 0.0 6.7 7.8 3.0 5.3 14.5 5.7 3.7 9.5 7.5 9.7 11.1 ARMCX6 "FLJ20811, GASP10" ENSG00000198960 "Armadillo repeat containing X-linked 6" Q7L4S7 X 101615118-101618001 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043030, HPA048125" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nucleoplasm, Nuclear membrane" "HPA043030: AB_2678277, HPA048125: AB_2680275" "unprognostic (1.20e-1)" "unprognostic (2.80e-1)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.80e-2)" "unprognostic (1.73e-3)" "unprognostic (1.92e-3)" "unprognostic (4.13e-2)" "unprognostic (1.07e-1)" "unprognostic (2.26e-2)" "unprognostic (3.31e-1)" "unprognostic (3.74e-1)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (7.82e-3)" "unprognostic (2.38e-2)" 9.4 14.6 11.8 9.6 12.1 8.2 11.7 13.0 13.8 14.2 11.9 11.1 6.2 15.8 22.7 9.3 12.6 10.5 15.3 11.7 12.7 13.0 7.6 9.6 12.8 13.9 12.6 19.1 17.4 26.3 17.1 15.7 13.5 13.7 8.1 5.3 24.5 18.3 6.7 10.7 9.0 14.8 12.9 19.2 9.5 4.4 12.4 13.8 14.2 8.3 13.8 11.2 11.3 14.6 13.7 15.7 24.2 13.8 48.4 28.6 4.8 28.0 27.0 24.5 47.5 9.4 12.8 14.4 28.0 26.4 25.5 13.9 23.8 11.3 19.1 12.6 14.4 13.5 22.6 12.8 22.2 13.4 16.4 17.9 11.3 15.1 7.8 34.3 25.4 7.4 11.3 18.0 37.3 33.0 19.8 0.2 17.5 17.7 3.1 20.0 32.5 5.5 17.7 1.8 13.3 12.5 16.4 0.1 21.0 18.3 11.4 6.4 19.8 29.7 13.4 41.8 6.6 22.1 12.6 0.0 8.9 3.5 9.9 11.3 3.7 6.1 5.8 6.7 7.5 13.2 6.1 6.4 7.6 9.0 7.3 6.9 0.4 8.3 5.1 13.2 3.6 6.2 11.8 12.1 13.0 13.8 11.7 12.7 13.9 12.6 13.5 12.9 12.4 14.6 23.9 9.6 9.1 5.2 28.5 13.4 14.4 28.3 26.2 5.5 39.3 44.4 9.7 14.3 16.3 31.3 16.7 37.8 40.6 2.2 23.5 44.2 0.6 21.9 23.7 27.2 16.4 13.0 1.9 27.7 17.3 24.6 19.9 38.0 14.5 30.2 25.4 15.7 67.9 10.1 3.3 14.2 16.2 29.0 32.3 2.2 18.6 40.8 37.4 5.6 28.5 30.3 36.0 8.5 4.9 26.5 11.2 19.9 23.8 18.3 7.6 25.0 5.5 4.6 26.3 13.1 22.4 2.6 2.3 32.7 16.1 34.5 26.0 29.5 11.7 20.8 ARMT1 "C6orf211, FLJ12910" ENSG00000146476 "Acidic residue methyltransferase 1" Q9H993 6 151452258-151470101 "Predicted intracellular proteins" "DNA damage" "Hydrolase, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003004, HPA005819" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 410000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA003004: AB_1078358, HPA005819: AB_1845741" "unprognostic (5.16e-3)" "prognostic unfavorable (7.09e-4)" "prognostic favorable (4.14e-4)" "unprognostic (6.39e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (1.37e-2)" "unprognostic (9.47e-2)" "unprognostic (2.33e-2)" "unprognostic (2.16e-1)" "unprognostic (2.24e-1)" "unprognostic (3.28e-1)" "unprognostic (3.16e-2)" "unprognostic (1.49e-1)" "unprognostic (9.78e-2)" "unprognostic (4.12e-1)" "unprognostic (1.22e-1)" 17.1 16.0 8.5 15.3 9.5 5.5 25.0 9.6 12.2 16.1 8.3 16.6 18.9 16.0 16.1 12.0 12.6 11.3 16.8 8.6 10.0 41.5 37.6 19.5 21.0 9.0 9.1 11.9 6.8 11.6 5.3 22.2 9.1 12.2 17.6 16.4 7.6 11.1 19.0 8.8 14.5 14.9 9.6 12.8 14.1 14.1 9.8 15.6 27.7 22.6 18.5 17.3 8.1 9.0 24.6 18.4 37.9 34.2 30.3 47.4 60.9 44.8 39.1 36.9 48.4 47.8 19.7 36.2 29.5 31.8 33.7 24.2 112.7 33.5 61.7 40.6 34.9 26.0 21.7 55.9 37.8 50.1 31.7 38.2 23.3 49.3 29.2 30.6 52.8 27.0 38.5 44.3 46.4 101.8 31.7 47.4 64.4 23.7 15.3 41.0 32.7 28.6 112.6 31.2 15.6 10.2 37.5 34.9 23.8 67.4 98.9 38.6 44.6 17.9 25.0 66.8 36.3 21.1 28.5 43.7 31.7 60.7 21.6 53.8 26.9 52.0 13.5 34.5 18.1 17.5 17.4 14.5 22.9 14.7 15.9 14.8 22.1 21.0 33.4 8.5 25.1 21.1 8.5 9.5 9.6 12.2 8.6 10.0 9.0 9.1 9.1 9.6 9.8 9.0 16.3 25.6 40.4 6.5 13.2 0.0 8.4 0.0 11.4 10.0 33.5 16.3 18.6 14.3 6.2 23.9 8.4 31.7 12.6 10.6 45.0 19.5 1.4 19.4 29.3 10.6 4.9 6.5 11.4 17.8 39.0 14.2 12.2 23.3 3.8 7.7 15.4 48.7 35.4 8.4 9.8 8.9 0.0 34.0 0.0 3.1 19.3 23.6 0.0 5.6 36.0 17.3 18.6 6.6 8.9 19.5 7.2 14.7 15.2 5.4 18.6 79.3 10.9 20.9 0.0 6.7 14.3 25.2 14.8 11.1 0.0 36.0 14.0 15.5 10.7 9.6 ARPC5 "ARC16, dJ127C7.3, p16-Arc" ENSG00000162704 "Actin related protein 2/3 complex subunit 5" O15511 1 183620846-183635783 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022013, HPA031972" Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane, Cell Junctions, Cytosol" "HPA022013: AB_1845045, HPA031972: " "unprognostic (3.82e-1)" "unprognostic (8.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.36e-2)" "unprognostic (1.74e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (5.90e-3)" "unprognostic (3.84e-2)" "unprognostic (3.17e-3)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-10)" "unprognostic (3.03e-2)" "unprognostic (4.66e-2)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" 86.1 49.2 17.4 148.2 22.5 69.1 48.8 23.7 23.8 46.5 13.0 104.7 99.5 69.5 15.7 77.8 52.0 52.9 35.7 20.0 22.3 39.0 64.3 103.1 158.9 35.2 22.8 30.6 51.7 29.9 19.7 108.2 29.7 46.0 68.9 8.0 45.9 35.9 18.7 42.6 117.4 78.9 24.0 120.8 88.6 38.4 24.1 130.5 46.0 22.5 131.3 75.9 51.8 37.8 313.4 167.7 141.0 98.1 114.0 161.5 338.7 419.7 317.9 176.3 143.0 150.9 215.9 284.9 463.9 241.7 114.6 211.2 101.1 141.6 93.9 413.6 87.1 172.9 212.6 132.6 185.2 254.8 325.0 197.6 148.2 215.7 170.3 201.2 213.7 196.1 133.3 229.1 233.9 125.6 238.5 67.9 133.7 238.5 63.0 219.2 126.3 278.6 97.3 158.7 61.1 164.7 435.8 186.1 167.3 147.1 185.2 222.5 480.9 259.0 134.5 293.8 410.1 270.1 321.8 196.2 204.5 179.6 204.6 1221.0 987.7 1563.7 395.7 1110.1 315.7 338.3 382.3 407.1 838.9 339.7 409.4 415.4 1852.1 392.6 1267.7 394.3 512.4 1913.3 17.4 22.5 23.7 23.8 20.0 22.3 35.2 22.8 29.7 24.0 24.1 37.8 148.7 375.0 188.9 8.1 163.3 249.1 178.3 275.9 91.0 34.2 79.9 118.9 30.2 150.2 197.6 82.8 14.6 475.1 227.4 283.5 166.3 344.3 35.5 78.8 211.4 186.7 202.0 90.0 21.6 280.2 734.2 166.2 87.1 119.8 258.8 147.7 181.7 87.4 608.5 38.7 13.8 146.6 238.0 556.3 740.8 24.2 125.9 558.5 254.3 20.6 635.1 56.7 423.3 7.5 51.5 381.6 234.5 183.6 132.1 182.6 213.6 152.0 95.2 25.4 243.3 83.9 286.8 151.9 137.3 161.5 244.9 199.5 234.4 144.4 155.4 234.6 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ASB7 ENSG00000183475 "Ankyrin repeat and SOCS box containing 7" Q9H672 15 100602589-100651701 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003300 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" Nucleoplasm "HPA003300: AB_1845071" "unprognostic (1.38e-1)" "unprognostic (3.48e-2)" "unprognostic (3.91e-2)" "unprognostic (4.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (5.55e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" 4.6 3.6 4.2 4.5 4.7 12.8 5.1 4.9 4.6 5.2 5.6 6.8 4.6 5.3 6.5 4.6 5.7 3.8 3.9 4.2 4.1 6.7 6.8 4.9 6.3 4.5 4.3 5.7 3.5 6.7 3.1 4.3 4.2 4.7 6.3 4.9 4.5 4.3 3.1 4.4 4.4 6.0 4.2 5.9 4.3 6.8 4.9 7.0 6.2 4.7 6.3 5.1 3.5 5.0 6.7 14.5 6.6 7.9 8.6 9.2 7.5 7.2 13.0 11.8 12.3 8.8 13.2 10.9 6.4 9.2 11.6 14.5 9.2 9.4 12.2 7.6 9.8 14.4 9.0 8.8 13.0 8.6 12.3 8.9 10.3 9.6 15.8 11.4 11.0 11.7 8.6 8.9 6.8 7.2 6.7 8.7 6.3 14.9 6.9 9.0 14.1 9.2 11.8 14.8 6.5 9.2 11.1 10.8 15.0 12.5 7.6 10.7 8.4 10.3 9.5 7.3 10.2 10.6 23.5 10.4 8.0 7.8 8.3 1.2 5.8 10.2 5.2 4.7 4.2 4.3 4.5 6.4 5.1 4.2 6.2 4.4 5.2 4.3 3.1 3.3 5.7 4.8 4.2 4.7 4.9 4.6 4.2 4.1 4.5 4.3 4.2 4.2 4.9 5.0 4.6 0.0 5.4 14.7 6.6 6.5 2.3 3.5 13.1 4.9 6.2 4.1 3.4 12.8 6.4 3.7 6.2 3.8 9.9 12.9 1.9 5.7 4.0 8.1 8.3 6.7 8.4 3.0 20.6 4.9 3.0 4.0 7.1 8.1 10.8 7.3 4.2 8.0 6.0 13.5 15.0 6.2 4.1 7.8 4.3 2.1 5.0 5.2 3.6 20.6 7.8 3.1 6.2 16.6 17.4 6.5 9.7 5.3 4.9 5.5 5.4 7.1 10.3 5.0 0.0 4.3 4.3 9.9 8.2 10.8 4.5 5.9 8.2 6.7 5.8 5.6 ASCC2 "ASC1p100, DKFZp586O0223, FLJ21588" ENSG00000100325 "Activating signal cointegrator 1 complex subunit 2" Q9H1I8 22 29788609-29838304 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001439, HPA052879" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA001439: AB_1078229, HPA052879: AB_2732577" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (8.58e-2)" "unprognostic (3.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.45e-3)" "unprognostic (3.01e-3)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (5.39e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.97e-3)" "unprognostic (5.19e-2)" "unprognostic (7.53e-2)" "unprognostic (3.81e-1)" "unprognostic (2.05e-3)" 26.6 31.3 11.4 22.7 12.7 53.7 24.9 12.6 13.7 23.7 16.7 24.5 23.7 21.0 16.1 42.0 19.9 17.1 22.8 11.6 11.9 19.8 35.8 22.1 24.5 13.5 12.9 19.9 23.5 21.8 26.7 21.8 13.2 27.1 24.6 8.4 29.8 18.0 43.5 30.1 23.1 19.2 12.9 29.4 37.0 24.5 12.5 29.6 28.3 32.3 34.0 26.8 27.5 13.3 46.9 26.8 28.4 38.7 41.6 36.7 40.7 47.6 36.3 48.4 48.1 31.5 24.7 46.5 33.4 46.2 30.7 55.5 36.8 54.0 40.5 59.8 64.3 39.9 33.0 38.0 52.1 72.3 115.6 39.6 48.2 55.0 50.0 28.4 42.9 30.7 41.8 43.7 44.3 57.8 44.5 37.9 20.7 65.6 36.0 53.0 34.9 48.6 29.6 76.1 43.8 38.5 44.3 48.2 35.4 28.8 34.3 37.4 42.8 67.1 11.3 41.2 47.9 51.9 42.8 54.4 39.2 39.9 49.5 44.7 29.8 53.6 32.1 49.2 28.4 18.8 23.6 26.9 37.7 15.0 24.1 24.6 9.2 33.7 43.9 21.7 30.3 20.0 11.4 12.7 12.6 13.7 11.6 11.9 13.5 12.9 13.2 12.9 12.5 13.3 27.7 19.2 14.7 18.6 35.8 30.0 25.2 38.1 13.1 9.4 23.3 12.3 19.1 31.5 33.3 40.5 4.2 46.3 40.5 38.8 11.7 25.4 110.2 14.0 28.1 20.7 15.5 116.0 13.5 24.9 63.3 22.9 69.8 20.0 34.9 24.3 22.9 25.7 30.6 5.0 13.8 23.2 44.7 29.2 37.3 155.2 31.1 29.1 28.4 11.2 27.9 12.2 56.7 15.6 16.3 27.7 34.0 24.8 32.4 16.2 46.8 18.2 24.4 13.6 19.7 19.6 19.7 48.4 22.5 35.0 39.2 44.3 34.9 27.8 23.9 34.2 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase and isoaspartyl peptidase 1" Q7L266 11 62337448-62393412 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.7;cervix: 121.7;testis: 100.5" "Cell type enhanced" "Detected in many" "Early spermatids: 372.5;Endometrial ciliated cells: 414.6;Glandular and luminal cells: 437.1;Late spermatids: 597.6;Proximal tubular cells: 214.1;Spermatocytes: 534.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 277.9;eosinophil: 269.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 277.9" "Cell line enhanced" "Detected in many" "EFO-21: 85.2;HAP1: 83.9;SCLC-21H: 112.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: AB_2665720, HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favorable (6.14e-4)" "prognostic favorable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favorable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 13.8 3.7 94.2 6.5 95.4 14.4 12.0 92.5 103.5 121.7 71.7 14.2 6.8 26.4 3.1 2.1 68.1 11.2 6.2 87.1 93.3 42.5 10.2 25.8 5.6 87.5 102.7 1.8 13.4 2.3 21.2 3.2 87.6 23.8 17.1 17.8 13.2 7.2 7.3 2.9 9.5 4.4 83.4 4.7 15.1 100.5 112.7 10.3 6.7 3.0 4.7 4.3 2.0 90.0 2.4 19.5 20.9 27.2 0.1 0.0 16.4 2.3 0.8 3.6 3.5 32.0 8.5 1.9 85.2 0.3 9.3 1.8 83.9 0.7 4.2 2.6 34.4 1.2 28.1 23.5 0.6 24.0 30.8 0.8 0.2 1.6 0.4 1.3 39.4 47.8 24.5 21.5 0.9 37.5 65.3 15.9 28.5 13.6 15.2 26.1 12.5 11.8 73.3 5.9 112.3 16.1 16.4 28.2 14.4 21.2 15.0 12.1 2.0 0.4 15.4 1.2 9.5 32.8 33.6 3.0 0.8 12.3 9.7 277.9 68.6 269.5 2.8 50.8 1.9 2.4 1.0 3.3 39.7 1.5 2.3 3.4 16.3 11.5 38.5 7.2 0.8 24.2 94.2 95.4 92.5 103.5 87.1 93.3 87.5 102.7 87.6 83.4 112.7 90.0 29.2 6.4 27.8 56.8 5.2 3.4 2.5 2.2 0.6 24.4 13.8 6.6 2.4 42.9 4.1 22.0 33.3 2.3 3.2 14.0 133.1 30.3 372.5 414.6 39.9 31.2 47.2 14.1 13.9 22.3 2.4 4.0 19.9 437.1 80.9 16.6 49.2 3.7 25.0 16.8 18.6 67.4 6.1 11.4 6.4 597.6 8.7 26.9 1.8 9.4 10.5 80.8 4.1 15.1 22.0 7.8 7.5 7.2 13.9 35.4 2.9 214.1 5.4 37.1 13.1 7.7 6.1 534.3 48.6 0.1 1.3 0.8 7.8 10.8 36.0 15.9 ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Spermatocytes: 73.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" 0.7 0.4 0.3 2.1 0.2 12.3 1.2 2.6 0.5 0.8 0.1 1.2 1.4 1.0 0.4 1.3 0.7 0.5 0.4 0.3 0.2 0.4 0.5 0.8 3.6 0.2 0.1 0.9 0.5 0.3 0.5 1.4 0.3 0.6 1.6 2.5 0.7 0.4 0.4 2.5 1.4 0.6 0.1 1.4 1.1 2.0 0.3 5.3 0.6 0.1 2.9 0.6 0.9 0.6 7.2 6.0 14.0 13.3 0.3 1.4 5.5 6.3 3.2 6.9 9.8 6.6 5.1 19.5 5.9 2.9 4.7 13.0 9.1 4.7 12.4 4.4 7.9 11.7 8.0 4.6 0.2 23.1 9.2 0.6 0.6 10.1 3.5 1.4 3.6 18.7 18.7 15.9 4.6 4.2 26.1 11.5 8.2 5.3 2.9 17.6 26.4 9.3 1.8 7.6 8.1 7.2 7.0 4.0 3.7 7.6 7.6 10.2 2.8 8.3 11.3 12.0 11.4 5.2 5.9 24.0 3.6 10.7 8.4 0.4 0.2 0.3 0.3 0.3 0.2 0.3 0.1 0.2 0.1 0.4 0.2 0.2 0.6 0.6 0.1 0.5 0.3 0.1 0.3 0.2 2.6 0.5 0.3 0.2 0.2 0.1 0.3 0.1 0.3 0.6 4.3 3.2 4.1 6.8 9.9 4.7 3.1 2.6 3.4 19.3 4.7 5.1 2.7 0.0 2.6 3.7 0.0 21.7 10.7 6.6 0.0 4.1 13.9 4.4 8.5 5.4 0.0 59.3 20.4 2.9 21.1 5.4 9.7 5.1 3.8 32.6 2.9 0.7 8.7 11.8 17.4 8.6 2.0 2.8 7.4 7.8 3.7 5.7 7.2 11.2 10.0 2.9 12.3 16.6 14.9 4.0 2.4 2.2 24.4 2.4 2.3 0.5 2.7 21.3 0.0 7.4 6.5 73.3 34.5 9.3 4.5 7.9 10.5 8.4 13.0 2.3 ATG13 KIAA0652 ENSG00000175224 "Autophagy related 13" O75143 11 46617527-46674818 "Cancer-related genes, Predicted intracellular proteins, Transporters" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039350 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA039350: AB_10673142" "unprognostic (3.66e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (5.36e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.59e-5)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (7.57e-2)" "unprognostic (2.44e-2)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" 32.3 39.7 55.9 26.1 67.6 60.5 30.1 49.4 63.7 30.6 46.1 26.5 29.3 28.2 32.2 32.0 32.1 29.6 36.8 55.2 51.8 28.7 43.9 25.3 31.5 60.2 59.4 29.7 44.6 37.5 57.7 21.9 61.8 31.1 24.1 48.4 35.9 25.5 34.5 39.6 28.0 24.8 51.8 36.4 36.4 82.0 59.6 40.6 36.8 33.4 33.6 27.4 29.1 87.9 32.8 58.5 44.1 26.1 60.2 70.0 44.5 37.5 65.4 45.0 57.0 40.2 31.7 30.2 25.6 56.5 58.1 38.8 42.7 50.3 45.2 57.9 81.1 32.8 39.7 71.2 67.4 44.1 54.1 84.9 59.0 31.0 67.9 63.9 45.0 69.4 57.8 66.8 40.8 48.8 44.0 65.1 55.0 59.5 49.9 41.4 57.0 53.7 29.9 34.5 41.6 42.1 51.2 40.6 55.4 42.1 58.0 89.5 44.6 54.7 33.3 51.1 41.2 61.1 73.8 38.6 67.8 39.3 40.9 41.7 36.1 48.5 35.1 42.6 27.9 27.1 31.2 27.8 35.0 21.7 26.4 29.2 67.7 31.5 35.1 25.6 44.7 39.9 55.9 67.6 49.4 63.7 55.2 51.8 60.2 59.4 61.8 51.8 59.6 87.9 10.6 16.0 16.2 14.7 16.9 9.3 12.0 9.0 13.1 22.7 16.7 12.3 13.2 8.6 12.0 12.9 39.6 9.9 25.4 24.5 7.9 18.9 42.7 30.0 17.3 12.7 18.0 28.2 23.4 32.3 22.4 14.8 20.9 46.1 8.8 22.5 13.2 22.5 15.1 33.7 25.7 22.6 14.2 19.1 9.8 46.8 11.5 15.7 12.4 15.0 22.8 16.3 19.6 25.1 61.0 30.4 12.9 11.3 36.6 19.9 19.5 13.5 9.4 32.2 13.1 16.9 19.9 46.3 16.3 15.8 11.5 26.4 18.0 9.8 11.9 24.3 ATG7 "APG7L, DKFZp434N0735, GSA7" ENSG00000197548 "Autophagy related 7" O95352 3 11272309-11557665 "Predicted intracellular proteins, Transporters" "Autophagy, Biological rhythms, Protein transport, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Excitatory neurons: 178.7;Inhibitory neurons: 176.4;Late spermatids: 119.1;Microglial cells: 132.1;Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 60.1;classical monocyte: 136.6;eosinophil: 88.4;intermediate monocyte: 79.4;myeloid DC: 82.4;neutrophil: 107.4;non-classical monocyte: 60.8" "Group enriched" "Detected in all" 5 "dendritic cells: 82.4;granulocytes: 107.4;monocytes: 136.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007639, CAB018771" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 33000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane" "CAB018771: AB_2062165, HPA007639: AB_1845162" "unprognostic (3.97e-2)" "unprognostic (2.83e-2)" "prognostic favorable (9.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.79e-1)" "unprognostic (5.19e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.80e-3)" "unprognostic (2.30e-2)" "unprognostic (2.67e-1)" "prognostic favorable (9.55e-4)" "unprognostic (1.61e-1)" "unprognostic (3.65e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" 16.8 13.5 11.2 25.0 13.1 47.6 18.0 7.3 21.8 14.5 17.0 17.3 13.0 14.9 16.7 16.7 18.7 16.6 10.8 12.4 9.5 13.7 13.2 20.9 23.9 15.0 15.0 12.2 10.9 21.2 7.5 21.0 13.1 11.6 19.2 10.3 12.2 11.9 13.0 18.0 13.8 20.0 12.4 16.4 14.4 22.5 15.4 13.1 13.0 13.5 25.0 20.3 12.0 21.3 48.5 37.1 16.7 9.2 28.0 36.7 80.4 44.5 56.8 43.1 49.9 16.0 42.5 22.1 26.5 39.2 45.1 14.5 18.3 62.0 73.8 19.8 23.5 16.0 33.6 19.6 36.9 46.8 50.8 38.0 28.2 83.6 52.0 45.4 60.5 14.0 24.1 17.9 60.6 31.3 13.7 21.3 13.0 22.2 47.9 17.1 19.6 19.9 32.5 34.2 14.6 14.5 31.6 26.4 17.5 20.1 28.8 44.7 42.5 36.0 25.7 23.6 63.2 11.1 31.8 38.1 57.8 43.1 49.9 60.1 136.6 88.4 15.9 79.4 12.3 13.0 12.9 15.1 82.4 12.3 11.7 13.7 107.4 21.3 60.8 14.7 12.4 56.8 11.2 13.1 7.3 21.8 12.4 9.5 15.0 15.0 13.1 12.4 15.4 21.3 6.4 0.0 9.8 160.0 11.4 11.1 7.3 21.6 9.6 18.1 7.4 3.6 4.2 4.3 12.5 7.3 18.8 16.5 7.9 8.3 7.9 12.3 44.2 10.6 9.5 14.6 11.4 9.5 178.7 12.9 16.8 11.0 10.7 13.2 14.7 12.4 19.6 9.0 57.6 20.2 176.4 7.6 22.4 25.8 12.1 119.1 10.2 28.8 3.6 132.1 30.6 8.1 13.4 99.0 137.2 17.4 7.3 9.8 10.8 6.4 8.4 6.8 16.5 12.5 6.6 11.7 10.6 22.4 11.9 9.8 7.7 19.2 10.1 9.9 7.6 7.4 ATOH1 "bHLHa14, HATH1, MATH-1, Math1" ENSG00000172238 "Atonal bHLH transcription factor 1" Q92858 4 93828753-93830964 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 20.0" "Cell type enriched" "Detected in some" 30 "Intestinal goblet cells: 226.1" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049400 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Mitochondria "Nucleoplasm, Cytosol" "HPA049400: " "prognostic favorable (3.26e-5)" "unprognostic (5.20e-1)" "unprognostic (2.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.70e-1)" 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.1 20.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 ATP13A3 AFURS1 ENSG00000133657 "ATPase 13A3" Q9H7F0 3 194402672-194498364 "Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 384.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029471 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoli "Plasma membrane, Cytosol" "HPA029471: AB_10600784" "unprognostic (5.07e-2)" "unprognostic (3.53e-2)" "unprognostic (2.94e-1)" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (9.87e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.22e-1)" "unprognostic (1.65e-1)" "unprognostic (1.34e-2)" "unprognostic (3.77e-1)" 38.0 22.5 8.5 32.0 9.3 36.9 22.8 12.2 14.8 17.0 18.4 21.2 20.2 18.9 17.0 18.0 17.4 24.2 55.7 10.4 9.3 36.2 87.0 35.5 20.8 9.7 8.4 15.9 16.4 50.3 15.3 54.8 9.1 15.5 22.0 11.6 21.8 15.2 17.0 11.5 16.6 16.9 9.5 16.9 24.4 9.6 12.8 16.3 46.0 14.4 19.4 40.1 16.3 10.1 184.6 19.3 33.0 35.2 49.7 64.9 96.8 62.7 75.4 74.9 132.5 114.1 45.2 74.2 161.1 89.4 197.9 64.2 37.5 66.9 171.4 175.5 31.4 43.1 24.8 31.7 77.1 139.7 91.6 32.6 36.8 127.8 89.0 105.0 38.0 34.9 46.2 139.1 90.7 41.0 53.9 34.8 41.1 64.5 33.5 40.0 77.1 48.8 71.6 53.4 52.4 30.5 64.1 77.9 52.9 31.2 127.7 92.4 37.1 81.2 64.2 162.1 116.5 93.4 141.2 116.6 149.3 80.6 55.7 0.2 0.4 0.4 0.4 0.6 0.5 0.4 0.4 0.7 0.6 0.2 0.5 0.5 0.0 0.6 0.2 0.3 1.0 0.2 8.5 9.3 12.2 14.8 10.4 9.3 9.7 8.4 9.1 9.5 12.8 10.1 56.6 51.3 34.1 51.6 22.3 82.5 49.1 42.1 21.1 25.9 32.1 16.6 50.0 78.6 35.9 49.7 20.9 29.6 26.6 43.7 3.9 66.6 2.0 52.3 65.4 50.5 30.6 23.5 61.8 71.4 19.0 53.2 42.8 181.8 8.8 27.9 68.9 153.2 37.2 15.2 80.6 24.1 26.4 31.1 384.4 2.3 10.2 110.1 62.2 76.8 27.0 8.4 18.6 64.3 49.6 87.8 23.7 13.2 37.8 94.3 11.6 41.4 31.7 13.6 13.1 35.8 42.4 15.2 6.8 36.5 71.2 64.6 24.4 14.1 24.7 69.9 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57906039-57959148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.7;Cytotrophoblasts: 14.4;Distal tubular cells: 17.6;Extravillous trophoblasts: 15.2;Proximal tubular cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A549: 1.0;Karpas-707: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: AB_10601026, HPA043204: AB_2678361" "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (5.28e-2)" "unprognostic (5.41e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" 7.5 4.9 0.6 0.4 0.5 0.1 5.6 0.6 0.9 4.1 0.5 8.1 0.2 3.1 0.0 5.6 3.2 0.0 4.6 1.0 0.3 4.0 5.2 2.6 0.1 0.4 0.2 3.1 5.9 0.0 2.8 0.1 0.4 3.3 0.0 0.5 3.6 0.0 12.4 4.4 4.3 0.0 0.3 3.2 4.2 27.8 0.5 0.0 3.5 0.0 0.1 4.7 4.0 0.3 0.6 1.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.9 0.2 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.6 2.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.8 0.1 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.6 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.0 0.3 0.2 0.2 1.6 0.1 0.1 0.1 0.1 0.0 0.6 0.5 0.6 0.9 1.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 8.0 0.0 9.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 7.4 12.7 0.0 0.0 1.8 3.7 0.0 14.4 4.2 0.0 17.6 6.1 0.0 5.6 4.9 2.8 0.0 0.0 0.0 10.7 15.2 2.3 0.0 6.0 11.4 6.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.9 0.0 0.0 26.1 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 3.0 9.5 0.0 0.0 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 130.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 294.0;Rod photoreceptor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" 17.7 28.2 30.6 18.0 35.2 21.5 16.3 16.8 42.7 13.4 0.0 22.1 34.6 20.9 19.6 17.4 17.1 22.7 18.9 43.6 44.1 37.4 21.0 24.1 13.1 25.6 26.2 20.0 17.4 86.0 39.0 21.2 34.6 17.4 20.5 130.7 13.5 18.6 59.3 28.1 24.3 21.5 12.1 21.8 16.3 18.7 30.9 15.2 30.3 25.3 14.9 11.9 12.8 27.2 18.4 37.0 22.1 40.1 36.5 31.7 12.9 12.7 23.3 26.4 34.2 23.9 39.9 3.4 22.6 26.2 36.2 38.7 34.5 21.5 30.4 28.3 36.2 29.2 27.3 19.0 22.7 12.8 50.9 23.5 30.3 42.4 18.0 32.6 18.9 13.2 108.0 111.3 39.7 15.8 5.1 11.3 14.3 23.9 0.4 0.2 23.0 51.2 30.2 14.4 60.9 32.0 19.7 17.7 37.1 28.8 43.0 19.0 11.4 22.3 0.9 33.0 15.3 45.0 66.1 6.8 29.7 0.2 26.5 21.6 14.5 11.2 1.0 4.4 1.6 4.7 0.7 0.2 12.2 7.3 1.2 0.9 18.7 0.1 3.3 6.2 3.7 6.6 30.6 35.2 16.8 42.7 43.6 44.1 25.6 26.2 34.6 12.1 30.9 27.2 20.0 19.2 48.0 47.0 23.0 19.8 56.7 15.7 32.5 164.8 15.7 16.5 21.1 28.6 18.3 14.7 294.0 34.3 16.7 46.2 11.7 16.3 4.0 32.8 27.4 22.2 84.9 45.8 125.0 18.5 15.7 31.0 23.4 74.0 24.1 74.5 16.4 37.8 53.8 95.9 112.3 27.3 12.2 37.8 29.2 3.9 17.4 42.8 40.9 38.4 17.7 59.3 3.1 61.3 80.5 24.2 37.6 23.7 13.8 32.7 56.9 32.5 11.4 403.4 6.6 39.4 32.3 38.8 18.2 21.7 20.2 99.9 6.9 35.0 24.5 14.9 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 6.6 4.4 5.6 7.0 6.2 10.4 5.7 7.4 6.5 4.7 6.9 5.5 8.7 6.0 3.9 4.3 4.8 3.8 4.7 6.0 6.0 3.8 4.2 6.3 8.3 6.6 5.8 4.1 5.7 3.7 4.9 3.7 6.5 4.7 5.8 6.7 7.6 4.0 6.5 9.4 7.0 5.1 5.6 6.6 8.8 4.9 6.2 7.5 4.8 3.5 8.2 5.3 4.5 7.9 4.8 10.3 12.0 17.8 9.2 7.0 6.7 6.2 6.2 5.4 5.8 6.9 2.7 18.0 4.2 7.6 5.5 9.0 16.1 6.2 4.5 11.4 10.2 27.9 9.2 5.4 10.2 16.8 51.0 6.7 4.4 5.9 7.4 9.0 5.0 15.0 14.5 3.4 8.1 8.4 15.4 24.8 11.5 6.6 6.5 15.7 9.9 6.4 8.3 10.4 7.2 13.6 9.3 6.9 9.4 6.6 5.9 14.4 8.3 8.0 3.1 10.8 9.1 10.8 12.8 14.9 9.4 12.1 6.5 6.3 0.7 13.7 1.7 0.9 1.0 0.9 1.7 1.5 0.8 3.7 1.6 1.8 2.0 1.7 1.5 2.8 1.0 0.8 5.6 6.2 7.4 6.5 6.0 6.0 6.6 5.8 6.5 5.6 6.2 7.9 13.0 6.4 11.0 3.9 20.4 10.1 10.8 4.6 11.4 20.5 7.9 5.3 8.8 12.8 8.3 9.2 12.5 5.2 27.9 17.9 0.0 8.1 10.2 11.0 11.9 10.6 13.2 50.3 21.2 10.9 5.7 11.3 18.3 12.3 75.3 8.7 18.2 11.4 8.4 11.8 19.3 9.8 2.0 9.4 17.2 4.5 8.7 11.3 1.8 7.5 13.2 9.0 25.7 10.6 17.1 9.2 9.0 9.4 19.7 15.7 11.1 4.0 13.5 28.8 6.6 12.4 10.9 23.6 12.6 9.6 14.2 6.8 21.8 5.7 11.4 11.4 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747033-113812056 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 463.7;Late spermatids: 870.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 79.2" "Group enriched" "Detected in all" 6 "dendritic cells: 38.8;granulocytes: 79.2;monocytes: 37.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" Nucleoplasm "CAB006910: , HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favorable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 18.1 32.2 40.1 21.6 46.4 16.6 24.5 14.7 53.0 25.3 62.4 22.1 18.5 14.2 15.1 22.7 19.0 20.9 9.0 47.5 58.5 92.7 36.4 24.5 25.1 39.6 23.0 11.3 20.9 60.1 17.1 24.5 39.0 20.9 22.5 58.7 37.5 14.9 7.9 25.0 15.9 15.8 16.9 26.5 22.1 18.1 28.4 22.9 40.8 11.0 28.0 19.6 14.2 21.9 61.7 27.4 33.9 29.7 70.0 30.9 36.0 32.7 49.4 33.7 46.1 52.4 48.3 50.4 75.5 48.0 37.3 39.1 77.5 43.2 43.8 23.1 21.4 44.8 39.3 40.6 57.6 33.2 50.0 42.0 29.1 43.7 30.2 52.0 55.7 25.1 52.0 37.0 50.5 40.5 24.4 14.9 42.8 42.9 34.3 20.8 24.6 57.4 92.5 58.0 65.4 24.1 57.3 38.6 44.9 46.4 58.5 26.6 51.4 31.1 23.1 21.7 19.8 38.4 44.5 46.2 61.1 41.2 35.3 26.8 37.0 12.8 6.3 27.7 5.9 8.2 5.6 6.0 38.8 6.8 5.4 6.2 79.2 9.2 23.9 10.8 8.1 16.7 40.1 46.4 14.7 53.0 47.5 58.5 39.6 23.0 39.0 16.9 28.4 21.9 18.8 28.9 35.0 43.4 24.2 30.3 15.9 30.3 23.9 94.1 27.9 17.1 10.4 31.5 32.9 99.3 41.7 22.0 20.8 38.3 82.2 29.5 463.7 41.7 24.5 26.8 55.8 49.6 119.4 27.5 22.6 17.9 20.9 100.6 10.8 19.4 36.0 74.3 74.3 101.0 107.7 25.4 197.4 104.7 73.3 870.3 18.0 70.9 46.2 34.7 82.8 45.6 11.3 54.3 53.2 27.1 30.5 23.0 23.6 25.6 24.1 80.8 38.3 44.4 6.6 15.3 21.6 28.7 15.7 40.8 47.9 43.9 19.0 25.8 27.2 26.8 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.8;Excitatory neurons: 28.5;Inhibitory neurons: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;T-cells: 3.7" "Cell line enhanced" "Detected in many" "ASC diff: 120.9;fHDF/TERT166: 112.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 17.2 9.5 8.2 22.7 7.8 5.4 14.0 18.8 11.0 28.7 20.7 17.8 12.5 39.2 17.7 11.0 30.8 18.2 15.2 10.8 9.2 6.3 3.4 18.0 25.4 8.9 8.1 35.3 5.9 10.5 19.3 15.3 9.6 18.9 9.1 2.1 7.2 21.2 3.5 8.5 17.6 39.7 5.6 19.5 14.5 16.3 8.8 18.4 15.0 7.4 19.6 19.7 17.9 7.7 2.1 15.6 20.0 20.5 120.9 80.4 0.3 41.8 77.4 26.1 30.5 0.3 0.6 1.9 21.4 112.4 17.7 9.2 23.0 5.5 19.3 46.6 16.8 19.7 20.4 18.9 37.2 0.1 14.8 53.4 1.3 40.6 38.7 35.6 40.0 25.1 37.6 47.8 22.7 21.8 36.2 2.5 43.7 0.4 17.4 39.9 12.7 71.5 5.3 0.4 17.4 22.7 11.3 2.8 30.3 28.3 14.9 15.3 34.7 40.2 19.2 51.4 13.5 58.0 75.7 11.1 14.1 2.2 24.7 2.8 0.0 1.7 1.1 0.0 0.7 0.3 1.7 1.9 0.0 0.2 1.4 1.2 0.0 0.5 0.0 0.3 3.7 0.5 8.2 7.8 18.8 11.0 10.8 9.2 8.9 8.1 9.6 5.6 8.8 7.7 6.4 3.2 4.5 26.8 7.7 2.5 1.4 0.9 0.0 4.5 1.9 2.3 6.2 0.0 1.9 0.0 2.1 0.1 16.0 0.1 0.0 1.6 0.6 6.5 20.5 9.0 0.0 0.4 28.5 0.2 0.5 12.8 0.5 2.4 7.6 10.8 13.6 0.8 0.4 8.4 31.7 0.2 0.0 1.0 4.2 1.4 11.5 1.3 7.2 4.7 0.9 3.4 7.2 4.0 4.2 0.9 0.0 14.7 13.9 5.6 0.0 0.2 4.4 0.5 0.0 9.5 11.2 2.6 4.3 0.6 1.6 0.3 17.2 6.7 0.1 0.8 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 78.1" "Cell type enriched" "Detected in many" 6 "Microglial cells: 248.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.2;NK-cells: 11.0" "Cell line enhanced" "Detected in some" "HMC-1: 40.2;NB-4: 19.2;THP-1: 26.7;U-937: 103.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 1.4 1.1 2.3 2.5 2.4 78.1 0.7 3.5 6.5 1.5 3.0 1.1 0.7 6.4 4.2 0.5 3.1 2.2 0.4 4.5 2.9 1.2 1.6 1.1 1.0 2.5 2.6 0.4 0.5 0.2 0.3 3.5 2.8 0.6 1.7 0.1 0.5 0.8 0.1 0.3 1.3 3.1 3.1 2.6 0.6 0.4 2.4 0.5 0.1 0.1 1.0 1.4 0.4 4.9 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.5 0.5 0.2 0.0 0.2 12.2 0.0 7.3 1.7 0.1 0.0 13.6 40.2 0.7 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 19.2 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.1 1.2 0.0 0.0 0.1 0.0 26.7 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 1.3 103.7 0.0 15.2 2.0 3.8 0.4 1.2 0.1 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.8 11.0 0.4 0.0 0.0 0.9 2.3 2.4 3.5 6.5 4.5 2.9 2.5 2.6 2.8 3.1 2.4 4.9 1.7 0.0 1.9 1.6 0.8 1.5 0.1 0.2 0.6 0.6 0.2 0.6 1.3 0.0 0.1 0.0 0.0 5.4 12.5 0.3 0.0 0.0 27.6 0.3 1.7 1.0 0.0 12.2 20.3 0.0 1.8 8.1 3.1 0.2 19.7 0.0 1.1 3.7 16.4 0.0 17.5 0.3 2.0 37.0 17.7 25.3 1.8 27.0 1.8 248.3 6.3 0.5 15.5 1.0 2.1 0.0 0.1 0.7 4.8 2.3 0.7 1.2 0.7 0.2 0.0 1.0 7.0 0.5 0.6 0.6 0.3 2.9 13.4 1.1 0.2 0.3 ATXN1 "ATX1, D6S504E, SCA1" ENSG00000124788 "Ataxin 1" P54253 6 16299112-16761491 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 582.5;Inhibitory neurons: 519.0;Oligodendrocyte precursor cells: 318.2;Oligodendrocytes: 466.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008335, HPA070756" Approved Supported Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "HPA008335: AB_1845129, HPA070756: AB_2686306" "unprognostic (1.01e-1)" "unprognostic (4.77e-2)" "unprognostic (1.23e-1)" "unprognostic (5.64e-3)" "unprognostic (4.54e-1)" "unprognostic (1.95e-2)" "unprognostic (7.74e-2)" "unprognostic (4.51e-2)" "unprognostic (4.06e-1)" "unprognostic (1.11e-2)" "unprognostic (3.87e-2)" "unprognostic (2.69e-2)" "unprognostic (1.41e-3)" "unprognostic (1.67e-3)" "unprognostic (2.33e-1)" "unprognostic (1.06e-1)" "unprognostic (3.29e-3)" 4.1 4.0 3.2 5.9 5.3 2.6 4.1 0.0 14.4 8.4 0.0 8.8 3.8 10.9 4.3 5.0 6.2 5.7 5.8 8.4 0.0 4.1 4.7 6.9 4.2 0.0 1.3 5.4 4.8 5.5 6.5 4.9 0.0 7.4 3.8 13.9 4.6 6.2 14.6 5.7 4.8 7.5 0.0 5.7 5.3 3.0 3.9 2.6 6.1 14.8 3.1 6.7 6.6 0.8 4.5 2.6 0.9 0.0 4.4 5.9 5.8 4.8 11.2 2.9 3.3 2.8 2.8 0.2 6.3 9.3 3.7 4.2 0.3 3.0 4.2 2.6 4.7 0.7 4.4 9.0 7.0 4.2 7.0 4.6 5.7 6.1 5.1 11.2 5.9 0.9 0.0 5.3 2.4 2.3 0.3 4.8 0.9 1.4 4.3 0.3 5.8 4.0 4.0 7.6 0.3 2.5 4.4 5.5 9.1 8.4 3.6 7.2 9.1 4.0 6.1 4.8 4.4 30.7 19.2 0.2 2.6 4.3 10.0 0.2 0.5 0.1 0.7 0.4 0.5 0.1 0.5 0.7 0.2 0.0 0.0 0.4 1.3 0.0 0.2 0.1 0.4 0.3 3.2 5.3 0.0 14.4 8.4 0.0 0.0 1.3 0.0 0.0 3.9 0.8 16.0 48.1 25.9 206.3 20.7 91.4 72.2 22.8 48.9 39.8 20.7 14.4 35.9 25.8 26.0 11.0 100.1 0.6 48.4 23.6 7.9 16.7 4.3 80.5 144.4 21.7 1.2 5.7 582.5 8.5 4.0 32.9 22.4 75.8 38.7 67.4 17.2 25.2 22.4 38.7 519.0 16.5 2.0 39.6 79.1 3.3 10.5 41.7 32.0 217.4 42.3 24.1 33.0 318.2 466.8 32.3 16.3 28.2 82.6 56.6 13.9 8.8 33.2 99.9 52.6 19.0 41.6 1.0 6.9 60.9 48.7 0.4 61.5 6.4 7.7 63.8 ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106621 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: AB_2686124" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" 9.0 5.9 3.8 5.7 4.2 9.9 6.8 4.9 5.0 7.5 3.3 7.3 3.7 6.4 4.3 10.3 6.0 6.5 5.3 3.6 5.0 5.6 9.6 6.8 7.7 6.2 5.7 7.1 4.5 6.4 4.0 7.0 6.2 6.0 6.8 3.9 5.8 5.5 3.3 12.9 4.8 8.6 4.3 5.6 5.2 9.3 4.3 8.0 5.9 5.9 9.8 9.0 8.0 4.9 8.6 16.7 14.6 13.6 20.9 20.1 28.4 9.7 15.4 11.9 16.5 12.3 23.2 17.6 18.5 15.8 14.1 14.6 11.6 21.0 26.3 20.0 3.5 7.4 8.0 18.2 17.3 13.5 12.6 16.5 18.1 20.9 21.8 15.9 18.7 19.4 10.1 12.5 18.2 33.1 14.0 11.9 10.4 28.5 13.6 11.0 27.0 9.9 15.3 19.4 5.3 8.8 23.1 9.5 13.3 19.6 18.1 9.1 10.0 11.7 17.0 7.5 5.2 10.8 19.8 16.2 8.3 12.9 6.9 13.5 14.3 10.8 6.1 16.5 7.4 7.7 7.0 6.9 16.2 10.6 7.8 8.8 12.2 8.7 23.0 9.3 8.1 6.3 3.8 4.2 4.9 5.0 3.6 5.0 6.2 5.7 6.2 4.3 4.3 4.9 55.0 16.0 12.4 33.6 27.6 25.4 28.6 29.8 19.4 35.4 16.9 18.4 19.3 15.7 20.0 42.3 50.1 20.3 31.5 13.8 15.6 25.8 19.8 20.3 34.9 53.0 16.1 30.3 36.1 17.3 29.8 34.6 18.3 22.5 24.6 25.9 49.6 21.1 22.4 26.9 28.6 16.4 12.2 35.1 27.2 26.8 67.7 30.0 23.2 28.1 48.0 20.4 29.9 39.2 51.5 19.6 16.1 65.1 20.1 31.9 16.6 17.7 16.0 46.7 46.0 51.9 38.2 39.1 57.2 21.6 30.3 25.3 28.8 24.8 18.9 28.2 ATXN7L2 "FLJ00381, MGC46534" ENSG00000162650 "Ataxin 7 like 2" Q5T6C5 1 109483479-109492804 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 7.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029827, HPA054952" Uncertain Approved "Nucleoli rim,Vesicles,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoli rim" "Vesicles, Cytosol" "HPA029827: AB_10602390, HPA054952: AB_2682647" "unprognostic (4.53e-2)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (3.90e-2)" "unprognostic (4.61e-5)" "unprognostic (2.40e-4)" "unprognostic (1.75e-1)" "unprognostic (3.53e-2)" "unprognostic (8.07e-2)" "unprognostic (2.77e-4)" "unprognostic (2.85e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (3.70e-2)" "unprognostic (1.08e-1)" "unprognostic (8.27e-2)" "unprognostic (3.94e-3)" 1.2 2.7 1.3 0.7 1.4 3.0 1.1 1.3 2.7 1.9 0.7 1.2 0.5 2.0 0.1 1.2 1.4 0.8 1.3 2.5 1.0 2.0 1.7 1.0 0.9 1.1 1.1 1.9 1.0 0.3 2.1 0.4 1.0 1.2 0.1 0.1 0.9 0.4 7.9 1.7 1.4 0.3 0.9 2.2 1.0 5.2 1.3 1.5 2.2 1.6 0.5 1.3 1.2 1.4 1.8 1.4 0.9 3.6 1.2 2.2 2.5 1.3 1.6 2.6 1.8 3.0 1.2 4.8 2.0 1.6 0.7 2.1 1.9 1.8 0.3 4.4 2.7 2.6 3.0 1.3 0.8 4.0 6.0 2.4 0.9 2.8 0.0 1.1 0.6 5.1 4.5 2.6 0.5 5.8 7.1 5.2 5.6 1.9 2.0 4.9 2.3 3.4 0.9 1.9 8.4 3.4 1.4 4.5 2.2 0.2 0.8 4.1 0.3 1.9 5.5 1.8 5.3 1.7 1.2 4.6 2.2 3.3 4.8 0.0 0.8 1.1 2.3 1.1 2.2 1.0 1.9 2.5 0.6 1.3 1.7 1.6 0.9 1.4 0.8 0.4 1.8 1.0 1.3 1.4 1.3 2.7 2.5 1.0 1.1 1.1 1.0 0.9 1.3 1.4 1.0 0.0 0.5 5.5 2.4 0.6 1.4 1.3 1.8 3.5 1.4 0.9 1.9 1.5 2.1 1.8 2.1 1.4 1.6 1.4 0.0 1.4 3.5 0.8 2.4 1.3 1.8 0.8 4.7 1.8 1.5 1.7 1.1 1.0 4.5 2.3 1.8 1.1 0.6 3.3 3.9 1.1 2.0 1.2 1.0 1.0 1.2 0.6 0.0 1.0 0.4 0.9 1.0 3.0 1.8 1.5 1.4 1.5 2.9 0.7 0.7 0.6 0.3 2.0 0.0 2.5 4.8 4.2 4.9 1.3 0.9 3.1 2.6 3.5 0.9 0.9 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.0;Oligodendrocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Actin filaments" Centrosome "HPA020863: AB_1845219" "unprognostic (1.54e-3)" "unprognostic (1.99e-1)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (6.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.29e-10)" "unprognostic (7.66e-3)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-3)" 13.7 11.4 8.5 7.2 8.6 4.4 10.8 8.9 10.1 11.4 10.5 15.2 7.4 12.5 5.2 12.3 11.3 6.4 28.5 8.2 9.2 5.5 16.9 7.2 4.8 9.2 9.0 10.5 20.8 3.0 5.8 12.4 9.4 9.4 9.4 2.5 7.9 9.1 31.1 11.2 7.5 12.5 8.8 6.5 12.3 10.7 9.0 6.9 5.6 13.6 7.9 16.2 10.8 9.1 16.4 26.3 26.0 8.6 21.4 24.1 14.7 41.1 36.2 31.9 19.9 7.2 11.3 15.2 24.8 34.8 24.2 10.4 12.2 26.9 25.7 14.6 7.7 26.1 15.9 20.5 31.5 26.6 18.2 19.8 50.9 18.4 45.8 38.6 35.2 7.6 26.6 21.1 45.6 17.3 10.5 46.1 11.9 22.2 8.5 15.7 14.6 32.2 26.4 21.0 13.4 16.8 22.6 11.6 11.4 10.7 12.6 29.4 24.5 27.7 9.5 12.0 34.6 21.2 17.7 31.1 13.3 31.0 15.2 0.0 0.2 0.0 0.5 0.6 0.6 0.4 0.5 0.2 0.2 0.1 0.2 0.3 0.0 0.5 0.2 2.3 0.9 0.1 8.5 8.6 8.9 10.1 8.2 9.2 9.2 9.0 9.4 8.8 9.0 9.1 9.0 3.2 5.3 16.6 5.6 5.7 8.7 1.8 3.4 5.6 7.5 9.0 32.7 2.8 0.8 0.0 6.2 11.0 10.5 7.4 0.0 2.9 13.8 4.4 14.3 10.2 4.8 9.5 21.8 8.6 44.0 8.5 5.6 5.6 0.0 14.7 8.6 19.1 7.4 8.4 24.1 7.7 0.0 4.1 4.4 6.5 7.5 5.0 3.6 22.5 3.5 10.9 7.2 26.7 86.6 7.0 5.2 10.5 15.6 21.5 9.4 4.6 1.5 5.3 6.6 4.9 9.7 6.2 7.4 12.9 9.7 9.4 6.5 23.1 6.0 14.7 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 B3GNTL1 B3GNT8 ENSG00000175711 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1" Q67FW5 17 82942155-83051810 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 19.9;Respiratory ciliated cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.1;HL-60: 27.0;THP-1: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023585, HPA024547" Supported Approved "Nucleoli,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli, Nucleoli fibrillar center" Vesicles "HPA023585: AB_2061075, HPA024547: AB_1845240" "unprognostic (1.51e-2)" "unprognostic (9.84e-2)" "unprognostic (4.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (8.11e-2)" "unprognostic (2.61e-7)" "unprognostic (9.95e-2)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (8.74e-2)" "unprognostic (2.80e-2)" "unprognostic (4.17e-9)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (3.39e-3)" 2.9 2.8 1.8 2.9 2.1 7.8 2.4 1.4 2.3 3.5 3.9 2.0 1.7 3.7 1.2 2.4 3.7 1.3 3.0 1.9 1.4 1.9 2.4 3.0 2.3 1.3 1.5 3.9 2.3 0.8 2.6 1.4 1.6 2.6 0.9 0.5 2.1 1.5 3.8 2.3 2.1 1.8 1.3 4.2 2.0 3.0 2.1 2.3 2.4 1.4 1.1 3.1 2.5 1.6 11.9 7.8 0.2 3.7 2.1 6.6 4.7 4.2 3.7 4.8 3.7 4.7 25.1 5.8 8.1 5.2 11.7 2.2 1.9 0.0 4.1 8.9 5.1 12.2 12.6 16.0 7.5 27.0 0.5 2.4 2.1 2.9 4.8 2.4 5.9 8.9 5.4 5.5 3.9 2.7 7.6 10.3 1.8 8.1 5.6 9.8 0.9 0.4 2.7 2.5 2.4 0.9 3.6 2.7 3.7 3.4 0.0 25.5 9.7 9.2 6.2 1.4 7.6 1.1 2.9 4.4 10.3 3.6 1.3 3.0 6.0 1.0 2.8 5.9 4.4 3.0 4.4 3.3 10.4 5.5 3.9 4.7 19.0 3.2 3.2 4.1 13.5 4.0 1.8 2.1 1.4 2.3 1.9 1.4 1.3 1.5 1.6 1.3 2.1 1.6 2.6 3.2 4.5 4.6 2.9 1.0 2.0 4.4 3.4 3.5 3.0 3.0 2.8 1.5 6.4 5.5 4.2 5.7 3.6 1.3 1.9 1.9 15.3 6.8 4.2 2.3 1.2 7.6 11.3 1.0 3.1 4.0 3.1 1.9 7.0 7.6 1.4 2.0 7.7 3.3 9.2 1.5 6.1 7.3 2.8 19.9 3.1 8.9 1.8 6.5 5.5 1.3 8.2 5.0 4.7 2.1 2.7 4.9 5.2 2.8 0.2 2.4 20.7 3.5 0.0 2.5 2.3 0.9 5.0 5.6 1.7 1.9 6.8 4.8 3.5 2.1 B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369499-382117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;ovary: 27.8" "Cell type enhanced" "Detected in many" "Astrocytes: 133.2;Bipolar cells: 23.8;Excitatory neurons: 31.2;Horizontal cells: 33.7;Inhibitory neurons: 32.3;Muller glia cells: 45.6;Oligodendrocyte precursor cells: 28.1;Oligodendrocytes: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 35.4;NTERA-2: 32.0;SCLC-21H: 39.5;SH-SY5Y: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043276, HPA053126" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA No "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cytosol" Vesicles "HPA043276: , HPA053126: AB_2682049" "unprognostic (6.11e-2)" "unprognostic (7.82e-2)" "unprognostic (1.79e-1)" "unprognostic (6.92e-3)" "unprognostic (5.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-3)" "unprognostic (4.99e-3)" "unprognostic (1.52e-10)" "unprognostic (9.01e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-4)" "unprognostic (1.25e-1)" 0.9 0.6 23.1 0.9 17.2 0.0 3.3 5.1 33.3 17.2 0.0 5.9 0.6 14.1 0.6 2.3 11.9 0.5 1.6 23.8 12.9 1.0 0.3 0.5 0.3 19.3 20.7 27.8 1.1 2.6 17.9 0.0 14.9 6.3 0.2 5.3 2.0 1.2 0.0 2.1 2.9 1.0 8.4 0.3 2.1 1.5 15.1 0.3 0.5 0.0 0.3 1.8 6.3 13.4 0.0 4.8 35.4 20.4 0.0 0.1 8.4 6.5 1.7 2.9 0.8 3.7 0.0 0.0 4.8 0.7 5.6 1.4 4.8 8.5 0.8 0.0 12.3 0.0 13.4 11.4 0.4 0.0 8.7 0.6 5.0 0.2 3.8 12.7 0.4 1.9 11.5 0.0 0.0 10.8 0.4 0.0 32.0 0.6 14.0 0.0 0.0 4.9 0.4 0.0 39.5 47.6 2.4 1.7 0.5 3.7 14.0 0.0 9.0 2.0 11.1 3.5 0.4 0.1 1.7 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 17.2 5.1 33.3 23.8 12.9 19.3 20.7 14.9 8.4 15.1 13.4 0.1 0.0 0.0 133.2 0.2 0.8 1.5 1.4 0.6 23.8 6.5 8.9 12.5 0.0 0.1 1.8 4.2 0.1 0.3 0.1 0.0 1.3 0.0 0.6 7.1 0.6 1.8 0.0 31.2 0.0 0.0 2.4 0.0 1.1 0.0 6.9 0.0 0.0 0.2 33.7 32.3 0.1 2.0 0.0 0.0 0.0 3.1 0.1 3.6 2.8 0.2 45.6 0.0 28.1 32.5 0.2 0.0 1.2 0.0 2.6 0.0 0.0 0.1 8.6 0.0 0.0 3.3 0.1 0.2 0.1 0.3 0.3 0.1 0.6 0.5 0.4 BABAM1 "C19orf62, FLJ20571, HSPC142, MERIT40, NBA1" ENSG00000105393 "BRISC and BRCA1 A complex member 1" Q9NWV8 19 17267376-17281249 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054386, HPA068786, HPA077609" Approved Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 47: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA054386: AB_2682471, HPA068786: AB_2686034, HPA077609: " "unprognostic (5.60e-2)" "unprognostic (1.08e-3)" "unprognostic (6.77e-2)" "unprognostic (1.06e-1)" "unprognostic (1.44e-1)" "unprognostic (2.18e-2)" "unprognostic (9.45e-3)" "unprognostic (2.05e-2)" "unprognostic (7.30e-2)" "unprognostic (2.03e-2)" "unprognostic (5.12e-2)" "unprognostic (7.21e-2)" "unprognostic (3.31e-3)" "unprognostic (1.74e-2)" "unprognostic (1.63e-1)" "unprognostic (3.79e-1)" "unprognostic (5.74e-2)" 45.8 54.1 51.9 40.0 55.4 70.4 46.8 44.7 66.7 49.9 39.4 60.6 41.6 50.3 28.7 48.3 44.5 28.9 72.1 58.3 53.9 53.3 55.3 42.8 55.4 50.4 51.5 44.2 49.9 46.8 32.2 46.7 54.1 48.0 36.3 26.4 50.2 37.1 134.1 46.1 50.6 37.3 44.0 60.7 54.2 41.6 51.4 51.3 37.3 96.9 51.3 49.2 43.4 54.7 126.8 69.5 68.8 66.0 72.9 51.9 154.9 73.5 96.0 143.2 142.1 78.2 146.5 87.8 172.1 102.2 64.9 61.2 79.7 102.2 89.1 127.5 130.9 78.6 91.6 99.0 60.4 142.4 96.0 79.6 68.3 96.4 56.1 79.3 122.5 123.9 132.9 101.1 103.3 104.1 138.7 135.8 182.0 106.3 147.0 95.5 92.2 119.4 104.1 62.1 66.3 120.3 90.5 92.8 84.6 77.2 81.4 115.2 91.7 87.8 55.7 108.8 124.3 133.1 172.5 119.7 125.6 187.0 85.5 201.3 154.3 167.7 132.9 148.1 128.3 141.9 121.7 129.2 161.3 143.4 111.8 109.9 37.9 114.3 147.8 134.3 180.2 214.1 51.9 55.4 44.7 66.7 58.3 53.9 50.4 51.5 54.1 44.0 51.4 54.7 40.8 12.8 29.7 11.1 45.0 34.9 41.5 63.4 19.4 21.9 53.9 60.7 37.8 41.5 44.9 35.0 14.6 172.4 51.0 51.1 101.8 70.1 65.8 18.4 30.4 39.9 43.8 78.5 18.6 72.4 155.4 41.4 26.0 28.1 46.3 54.3 40.0 50.4 98.7 16.8 16.2 60.6 48.8 46.8 45.6 106.3 36.7 43.2 65.8 8.4 80.4 35.3 68.0 8.5 12.3 69.8 63.8 44.4 51.7 44.6 68.1 89.3 23.5 18.5 39.5 34.7 52.5 57.8 74.2 27.9 41.3 158.0 46.4 43.0 64.7 45.5 BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 81.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 174.7;Breast myoepithelial cells: 163.2;Granulosa cells: 334.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 166.7;SK-MEL-30: 199.0;SuSa: 357.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: AB_2668371, HPA010866: AB_10601686" "unprognostic (7.02e-3)" "unprognostic (4.52e-2)" "unprognostic (1.28e-2)" "unprognostic (3.17e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (9.42e-6)" "unprognostic (1.09e-1)" "unprognostic (6.45e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-3)" "unprognostic (9.29e-2)" "prognostic favorable (5.25e-4)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "unprognostic (2.38e-2)" "unprognostic (2.10e-2)" 4.4 44.1 13.8 2.3 16.3 6.0 23.7 18.4 17.6 5.7 20.7 3.8 1.6 17.9 2.9 2.1 6.3 5.4 43.5 13.6 15.9 19.9 23.9 12.0 2.0 19.9 16.9 81.6 6.9 8.2 8.5 39.3 21.1 7.4 4.7 13.4 6.4 16.7 1.8 5.4 2.1 12.2 16.6 18.0 3.8 8.7 14.8 0.4 1.2 1.9 1.4 30.0 5.4 22.7 1.0 41.0 4.2 2.2 4.8 0.1 24.5 9.7 3.5 15.4 10.0 166.7 17.3 0.5 5.7 7.4 8.8 12.2 10.2 1.6 7.2 10.1 21.0 39.5 6.2 63.7 5.9 2.4 51.5 3.7 2.3 10.4 1.6 96.7 2.4 2.1 22.1 18.7 3.1 70.1 0.2 3.3 71.6 34.5 9.9 0.3 7.8 3.6 12.9 40.4 6.8 5.2 13.2 78.5 199.0 357.8 23.2 3.0 0.3 10.4 7.3 17.0 4.7 0.5 15.0 0.0 1.0 8.9 67.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.3 18.4 17.6 13.6 15.9 19.9 16.9 21.1 16.6 14.8 22.7 6.6 9.6 5.9 15.0 5.7 4.0 7.6 0.6 13.1 14.3 174.7 163.2 34.9 58.6 3.5 11.0 4.2 12.0 9.3 33.8 1.9 20.8 0.1 14.3 15.3 7.3 26.8 0.0 0.5 0.2 22.2 46.1 58.6 21.1 1.3 334.8 14.6 16.0 6.7 6.7 0.2 3.8 0.0 1.6 4.2 1.2 3.4 5.4 16.0 15.9 0.7 50.2 0.0 46.3 21.2 12.1 34.6 2.2 4.3 10.8 1.1 16.1 1.4 5.9 0.0 4.2 42.7 1.9 15.5 13.5 1.3 8.5 7.8 6.2 3.8 14.1 BANK1 "BANK, FLJ20706" ENSG00000153064 "B cell scaffold protein with ankyrin repeats 1" Q8NDB2 4 101411286-102074812 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.2;lymphoid tissue: 96.4" "Cell type enriched" "Detected in many" 10 "B-cells: 455.9" "Cancer enhanced" "Detected in many" "prostate cancer: 6.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 14 "memory B-cell: 310.4;naive B-cell: 253.0" "Lineage enriched" "Detected in many" 16 "B-cells: 310.4" "Cell line enhanced" "Detected in some" "Daudi: 13.6;HEL: 10.6;HL-60: 9.6;U-266/70: 31.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037002 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 19000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA037002: AB_10672383" "unprognostic (1.59e-2)" "unprognostic (2.08e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.73e-2)" "unprognostic (4.89e-2)" "unprognostic (1.62e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.25e-2)" "unprognostic (7.89e-2)" "unprognostic (2.80e-1)" "unprognostic (2.18e-1)" "unprognostic (2.75e-2)" "unprognostic (6.09e-3)" "unprognostic (1.75e-1)" 8.5 3.6 0.6 35.1 0.6 6.2 2.2 1.5 0.9 2.3 0.2 2.8 2.4 0.8 3.2 0.8 2.3 3.0 0.7 0.5 0.7 3.2 0.3 8.1 82.2 0.8 0.8 0.1 0.5 0.4 1.5 0.8 0.9 5.8 3.3 0.2 2.4 4.7 0.1 0.7 24.2 1.0 0.9 56.1 7.4 3.0 1.0 9.7 12.9 0.2 96.4 7.6 0.7 0.6 0.0 3.0 0.0 0.0 3.4 1.4 0.1 0.1 0.1 0.4 0.6 0.1 4.6 13.6 1.2 0.0 0.0 0.2 0.1 1.5 0.4 0.0 0.0 10.6 2.6 0.0 0.1 9.6 0.0 0.6 0.4 0.0 0.0 1.2 0.1 0.0 0.1 4.0 0.6 0.5 0.0 0.6 0.0 0.4 5.7 0.2 0.6 0.0 0.4 6.1 2.6 0.0 0.3 0.2 0.0 0.1 0.5 2.5 1.3 0.0 0.6 0.0 0.0 31.0 0.0 2.2 0.1 5.3 0.0 10.8 1.7 19.7 0.4 0.5 0.1 310.4 0.1 0.2 10.5 253.0 0.1 0.1 0.9 1.5 0.2 5.2 0.2 11.3 0.6 0.6 1.5 0.9 0.5 0.7 0.8 0.8 0.9 0.9 1.0 0.6 3.5 44.8 27.1 6.8 455.9 0.1 2.2 0.5 0.0 0.2 1.7 0.4 0.5 0.0 10.0 3.7 0.0 2.1 5.8 0.0 0.0 0.2 2.8 13.1 1.0 1.3 0.0 6.1 7.3 0.2 0.6 1.4 6.1 15.2 1.3 0.1 0.0 0.1 1.5 0.0 1.6 0.4 2.0 2.9 25.1 2.0 0.0 13.0 5.4 4.7 2.8 1.8 1.0 1.0 1.3 4.1 1.3 0.4 13.7 4.4 0.2 4.2 2.2 0.1 0.0 0.1 0.8 1.9 5.6 0.8 1.1 0.3 12.9 2.1 1.1 4.3 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.0;salivary gland: 131.4;vagina: 72.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 128.5;Breast glandular cells: 50.4;Squamous epithelial cells: 136.4;Suprabasal keratinocytes: 82.5;Urothelial cells: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HDLM-2: 163.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.8;hippocampal formation: 1.7" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: AB_781574, HPA064966: , HPA068414: AB_2685984" "unprognostic (4.25e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.22e-5)" "unprognostic (3.85e-2)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (1.43e-3)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.06e-4)" 0.3 0.0 0.1 1.3 0.3 0.0 14.9 1.1 0.3 24.2 5.5 7.0 17.9 0.1 0.2 158.0 16.7 4.7 0.2 0.3 0.4 5.4 0.0 0.3 0.7 3.0 1.6 0.0 10.3 0.3 1.7 3.6 3.2 4.8 4.9 0.2 131.4 0.6 2.2 34.8 13.0 0.2 1.8 0.0 6.4 2.4 0.4 0.4 0.3 39.3 8.8 0.4 72.2 2.9 23.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.3 0.0 1.0 20.9 0.0 5.1 0.0 163.7 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.1 0.0 3.9 0.0 6.2 0.0 0.0 0.0 20.6 0.9 0.0 0.0 39.8 0.0 0.3 0.2 0.0 0.0 19.4 0.1 0.4 3.8 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.3 0.3 0.4 3.0 1.6 3.2 1.8 0.4 2.9 0.2 0.0 1.1 0.3 0.5 43.1 128.5 8.7 3.4 0.6 50.4 16.9 0.5 4.3 8.0 0.0 0.0 13.4 0.8 29.4 7.9 23.7 7.2 11.3 0.6 1.2 1.8 0.0 1.8 0.7 5.8 2.7 6.6 4.6 0.0 0.0 0.0 0.2 1.9 0.0 0.3 13.4 0.0 0.3 2.2 1.6 0.0 0.7 10.6 0.0 0.1 0.7 0.0 0.0 0.3 6.2 29.8 0.4 0.9 25.6 34.0 3.4 11.8 0.3 0.0 0.6 1.7 0.1 5.3 136.4 82.5 4.2 1.7 0.0 19.4 84.8 BATF3 "JDP1, JUNDM1, SNFT" ENSG00000123685 "Basic leucine zipper ATF-like transcription factor 3" Q9NR55 1 212686417-212699840 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 41.0;Langerhans cells: 50.4;Macrophages: 24.4;monocytes: 65.7;Smooth muscle cells: 20.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 65.9;myeloid DC: 55.3;non-classical monocyte: 99.3" "Group enriched" "Detected in many" 34 "dendritic cells: 55.3;monocytes: 99.3" "Cell line enriched" "Detected in many" 11 "HDLM-2: 497.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA075858 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA075858: " "unprognostic (3.87e-2)" "unprognostic (2.10e-2)" "unprognostic (4.29e-2)" "unprognostic (6.85e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (3.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.08e-1)" "unprognostic (6.47e-2)" "unprognostic (1.28e-2)" "unprognostic (1.75e-1)" "unprognostic (6.43e-10)" "unprognostic (9.88e-2)" "unprognostic (5.19e-2)" "unprognostic (3.90e-1)" "unprognostic (7.08e-2)" 5.9 1.1 1.9 3.6 2.9 3.0 3.0 1.4 2.8 1.8 9.1 1.7 0.6 1.3 0.0 1.1 2.0 2.0 2.1 2.2 1.9 5.1 1.1 5.8 5.9 1.8 1.8 0.6 1.7 0.4 0.9 2.5 1.9 1.8 0.6 0.0 0.9 0.4 0.5 0.9 2.3 1.8 2.3 7.3 1.5 0.5 1.7 4.2 1.6 0.6 2.6 4.9 1.4 2.0 2.4 6.6 0.7 0.0 0.2 3.1 4.3 2.3 7.4 6.5 7.0 0.0 1.7 0.0 0.9 0.4 10.6 0.0 7.0 1.1 4.5 497.4 12.5 0.1 1.9 0.0 1.2 22.6 3.9 0.5 0.0 12.5 1.8 1.0 0.1 43.5 1.1 6.5 1.3 0.0 17.8 9.3 2.7 0.0 8.4 3.5 2.4 0.3 6.0 0.0 1.4 0.9 1.6 0.0 0.5 2.3 0.0 17.8 0.0 2.7 11.1 0.5 13.4 0.5 1.4 2.7 8.7 21.3 6.2 0.0 13.6 0.0 0.0 65.9 0.0 0.7 0.2 0.3 55.3 0.0 0.0 0.0 2.2 1.5 99.3 0.2 1.8 8.8 1.9 2.9 1.4 2.8 2.2 1.9 1.8 1.8 1.9 2.3 1.7 2.0 9.6 3.2 0.6 0.3 2.4 5.7 2.3 0.9 0.0 0.2 5.2 5.5 0.5 0.0 1.6 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.7 1.5 3.1 8.2 0.0 0.4 4.5 0.4 41.0 6.8 0.0 2.3 5.1 1.0 6.1 0.4 5.8 0.0 0.6 0.1 0.0 14.4 50.4 0.8 0.9 24.4 1.8 7.5 65.7 0.1 0.0 0.5 0.9 1.1 0.0 0.0 0.0 18.9 0.0 0.4 2.7 0.4 0.0 5.2 20.0 1.0 4.1 0.1 2.8 4.5 1.9 0.1 0.0 1.4 BBOF1 "C14orf45, CCDC176, FBB10" ENSG00000119636 "Basal body orientation factor 1" Q8ND07 14 74019349-74082863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.6" "Group enriched" "Detected in many" 4 "Early spermatids: 239.3;Endometrial ciliated cells: 166.4;Late spermatids: 111.3;Respiratory ciliated cells: 177.8;Spermatocytes: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003090, HPA003136, HPA075108" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "HPA003090: AB_1845571, HPA003136: AB_1078330, HPA075108: " "unprognostic (1.84e-2)" "unprognostic (1.31e-1)" "unprognostic (5.71e-2)" "prognostic favorable (6.34e-4)" "unprognostic (1.11e-2)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (2.08e-1)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" "unprognostic (1.01e-1)" "unprognostic (3.89e-1)" "unprognostic (1.40e-3)" "unprognostic (6.14e-2)" "unprognostic (2.57e-1)" "unprognostic (7.93e-2)" "unprognostic (6.04e-3)" 4.9 2.8 5.8 2.3 6.3 6.5 7.3 5.5 9.0 6.5 15.9 7.1 2.0 7.1 14.6 5.2 22.5 5.7 4.4 6.3 5.8 9.7 2.2 6.8 1.7 9.7 9.8 5.1 2.8 5.0 10.7 2.4 8.3 5.5 3.5 24.3 3.8 7.1 2.3 3.1 2.4 5.5 8.0 1.4 3.4 38.6 6.2 2.8 13.2 3.3 2.1 5.0 3.1 6.6 5.4 3.1 1.3 8.7 5.7 12.5 1.1 4.6 6.5 4.6 4.3 1.1 3.7 5.3 1.2 5.7 2.0 1.3 1.8 0.8 5.2 0.8 1.0 0.6 3.1 1.2 4.8 2.7 0.3 6.1 4.2 10.3 1.3 7.3 1.7 9.7 2.9 0.9 3.4 4.3 8.5 1.3 0.4 0.5 2.1 3.0 3.4 0.9 7.9 1.4 5.2 3.3 9.0 3.6 2.6 1.3 9.2 0.2 3.8 5.7 4.0 7.6 1.3 1.9 4.9 3.3 16.7 0.3 1.6 1.1 0.0 0.1 1.5 0.0 1.8 0.5 1.4 1.0 0.1 0.6 1.9 1.5 1.0 1.1 0.0 2.4 0.3 1.2 5.8 6.3 5.5 9.0 6.3 5.8 9.7 9.8 8.3 8.0 6.2 6.6 3.8 12.8 8.1 0.0 1.4 0.0 3.8 0.0 4.0 7.8 15.8 8.0 0.0 7.2 30.3 3.7 29.2 1.8 3.9 1.8 15.6 9.0 239.3 166.4 15.1 3.1 2.4 39.6 0.0 3.5 2.6 7.4 2.0 18.2 1.3 4.3 3.6 4.5 2.3 6.7 0.0 2.7 0.0 1.6 0.0 111.3 10.8 3.9 0.0 0.0 0.8 5.7 4.1 0.0 0.0 3.0 0.2 6.0 0.7 2.5 1.0 23.5 177.8 29.9 0.0 4.3 4.0 149.2 14.7 1.3 0.0 1.0 2.3 4.1 0.9 3.4 BCAR3 "AND-34, NSP2, SH2D3B" ENSG00000137936 "BCAR3 adaptor protein, NSP family member" O75815 1 93561741-93847150 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.5;Basal prostatic cells: 149.0;Extravillous trophoblasts: 75.0;Urothelial cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0;memory B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 159.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014858 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Centrosome "HPA014858: AB_1845302" "unprognostic (9.16e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.60e-3)" "prognostic unfavorable (8.41e-4)" "prognostic unfavorable (5.42e-4)" "prognostic unfavorable (8.92e-7)" "unprognostic (2.44e-1)" "unprognostic (3.66e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.51e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.13e-1)" "unprognostic (1.14e-1)" "unprognostic (7.05e-2)" "unprognostic (1.87e-1)" 31.0 10.6 17.7 6.6 20.9 1.0 18.5 19.3 15.3 10.0 21.1 15.3 13.4 5.7 3.6 8.1 9.5 7.5 13.1 14.8 18.7 15.9 11.9 14.2 13.8 21.1 20.6 11.4 4.2 4.0 4.6 17.0 18.9 8.9 16.6 1.5 21.9 9.5 24.4 15.6 12.9 8.0 19.0 4.8 16.2 6.3 21.7 4.3 10.4 21.1 13.0 13.6 9.8 17.8 56.0 23.4 43.5 3.4 18.4 14.4 37.1 56.9 98.3 45.9 28.1 4.0 40.9 9.0 18.9 88.1 59.4 34.0 1.3 73.5 39.7 4.0 1.3 0.0 16.2 10.3 33.1 0.4 0.2 17.3 79.5 47.5 159.7 44.1 51.1 1.1 1.6 0.3 125.7 8.6 1.0 0.2 13.6 24.5 79.7 3.7 62.7 1.3 120.4 70.1 1.5 3.6 27.4 29.1 36.1 16.8 32.9 2.2 60.8 67.3 17.5 29.2 76.0 4.5 2.1 1.2 10.1 0.2 25.2 2.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 17.7 20.9 19.3 15.3 14.8 18.7 21.1 20.6 18.9 19.0 21.7 17.8 26.9 3.2 7.2 72.5 10.2 9.8 149.0 11.3 2.8 0.9 7.9 13.5 7.1 11.5 11.7 14.7 0.0 27.5 2.5 30.8 27.4 11.3 11.3 13.3 2.6 17.9 14.9 0.4 5.2 6.3 75.0 6.3 15.8 16.6 3.8 33.7 5.7 10.3 11.9 21.9 11.2 20.7 8.2 5.3 12.7 12.8 10.2 8.3 19.6 64.6 9.4 4.0 0.0 3.0 2.1 28.0 22.0 1.2 8.9 36.3 25.8 23.7 18.1 0.4 72.3 23.8 19.9 4.2 3.7 4.8 10.2 18.9 3.7 8.3 10.3 106.1 BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.4" "Cell type enhanced" "Detected in all" "Astrocytes: 296.5;Early spermatids: 110.9;Inhibitory neurons: 94.9;Oligodendrocyte precursor cells: 98.5;Oligodendrocytes: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031580, HPA031956" Approved Supported Nucleoplasm,Nucleoli,Mitochondria "Intracellular and membrane" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Nucleoli" "HPA031580: AB_10696054, HPA031956: " "unprognostic (4.23e-1)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (9.37e-3)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.32e-3)" "unprognostic (2.67e-1)" "unprognostic (4.65e-2)" "prognostic favorable (5.54e-9)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (1.49e-2)" 19.7 10.7 7.3 7.6 8.3 8.2 22.3 11.5 7.8 11.7 11.6 22.5 11.5 9.2 7.1 10.3 11.5 7.8 18.8 8.8 7.0 31.8 78.4 7.3 8.8 10.7 9.2 14.6 12.9 19.7 7.2 4.8 13.1 15.9 20.7 7.9 26.6 11.3 10.9 8.5 12.4 9.4 11.8 6.3 17.6 13.1 8.7 9.1 15.5 15.3 9.1 11.2 7.6 16.0 13.8 5.1 18.8 25.3 18.6 16.1 14.9 9.7 19.8 15.4 21.0 8.3 18.5 38.9 10.1 23.1 18.0 13.6 10.6 12.7 21.5 48.8 15.6 19.4 12.6 11.3 20.7 27.7 8.3 15.6 12.8 10.7 13.3 13.8 18.6 29.8 16.6 33.8 35.0 7.6 10.3 16.3 14.0 30.1 6.5 25.5 58.3 33.8 43.2 20.7 12.6 17.8 16.2 13.4 9.9 20.6 17.3 21.1 8.0 9.2 6.3 8.5 13.0 24.0 25.2 12.9 11.3 20.4 14.2 3.4 4.2 1.0 10.1 5.1 13.3 10.6 8.3 8.5 8.3 12.7 11.0 11.6 0.8 17.4 5.9 12.9 20.3 6.1 7.3 8.3 11.5 7.8 8.8 7.0 10.7 9.2 13.1 11.8 8.7 16.0 8.4 9.6 21.0 296.5 11.5 8.5 12.5 21.1 15.9 7.8 19.6 14.7 29.3 8.6 18.0 5.5 2.1 17.0 9.1 17.5 27.4 8.2 110.9 8.3 10.3 8.0 12.0 10.3 72.0 10.4 8.3 13.7 15.3 17.6 16.5 19.2 11.0 66.5 12.2 3.3 94.9 31.3 10.2 9.1 9.0 13.7 8.7 5.4 16.0 59.0 7.3 15.5 10.3 98.5 101.7 5.4 10.4 8.6 8.4 6.2 11.5 33.1 13.5 8.7 6.6 11.1 9.4 15.2 5.6 20.1 12.4 10.4 9.9 15.5 17.4 10.9 BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 172.4;Squamous epithelial cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 67.3;Karpas-707: 54.1;SiHa: 69.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" 65.1 43.6 6.7 25.0 6.3 54.0 37.2 6.4 7.8 26.8 7.9 39.7 32.2 26.8 1.7 67.5 35.9 13.4 36.3 5.9 7.2 56.6 161.8 87.3 11.6 11.6 7.8 23.7 37.4 3.1 25.2 7.9 8.1 43.4 9.3 1.3 40.9 8.9 17.8 28.3 44.2 11.7 8.0 58.7 35.9 9.6 8.5 6.6 36.8 4.9 12.7 37.6 37.7 6.4 9.8 33.5 0.7 17.5 6.1 12.6 1.7 5.8 6.3 3.7 5.3 6.9 17.8 9.5 13.4 11.5 18.5 10.5 2.4 9.9 2.3 67.3 0.6 1.1 18.9 9.3 14.6 0.7 28.2 22.5 7.8 8.1 9.9 16.6 10.0 0.0 1.2 54.1 2.2 8.4 0.0 7.4 0.9 15.1 12.8 4.3 6.5 3.4 16.5 19.9 0.0 0.9 69.7 35.7 1.9 1.1 12.7 7.6 16.8 11.8 11.6 18.5 2.2 50.1 21.4 10.1 22.1 1.2 9.2 0.4 2.7 5.5 0.8 1.8 1.1 1.5 1.0 1.3 2.6 1.3 0.5 0.7 19.8 2.3 1.1 3.1 1.7 1.0 6.7 6.3 6.4 7.8 5.9 7.2 11.6 7.8 8.1 8.0 8.5 6.4 56.3 19.2 51.3 2.6 43.9 46.7 38.8 22.4 172.4 2.3 106.8 62.0 3.0 42.9 28.6 12.9 0.0 0.6 33.4 60.6 9.8 31.8 11.8 49.4 34.2 76.3 21.5 4.2 0.5 68.7 6.8 47.8 128.0 70.0 38.0 1.4 38.9 35.5 16.1 8.4 0.8 56.2 8.2 30.5 110.8 2.7 13.4 86.6 40.9 1.0 28.4 2.2 2.1 0.0 0.1 43.0 40.0 4.5 100.4 58.9 56.6 17.7 20.5 0.6 6.6 43.3 40.1 0.5 2.0 146.0 61.1 1.4 46.2 0.3 34.5 51.2 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 19.4 11.1 34.3 11.0 65.7 34.6 17.4 15.9 30.7 14.3 10.6 11.7 10.0 12.3 16.1 24.5 12.1 9.3 12.2 45.0 22.2 21.1 13.8 18.6 13.7 27.1 26.5 9.4 14.6 20.6 25.0 10.3 24.1 11.8 7.6 7.4 18.3 10.1 5.8 23.5 10.2 8.8 20.9 11.4 16.1 11.0 35.0 14.7 19.7 5.7 10.8 15.3 14.3 14.1 47.6 20.1 30.3 31.2 17.7 12.1 45.6 16.8 15.7 15.2 12.2 35.6 18.7 32.9 30.5 14.4 14.7 47.6 3.6 46.8 4.3 63.3 32.3 28.8 27.7 28.6 22.9 26.9 14.6 10.2 31.1 22.8 19.8 27.0 53.6 23.3 112.5 15.1 7.0 31.3 25.4 21.4 25.8 37.4 19.5 32.9 12.4 21.7 23.7 29.6 27.7 26.3 30.7 26.1 12.6 19.3 16.6 21.7 61.4 9.1 1.0 14.9 14.0 3.4 14.8 11.7 23.4 20.1 14.3 0.0 0.5 0.0 3.1 0.2 1.1 0.6 1.5 1.6 0.4 0.6 1.3 1.7 0.5 1.5 0.5 0.4 0.8 1.4 34.3 65.7 15.9 30.7 45.0 22.2 27.1 26.5 24.1 20.9 35.0 14.1 19.3 9.6 11.5 51.2 4.5 15.4 11.9 18.2 6.2 22.9 17.1 9.9 7.5 17.2 20.9 18.4 22.9 14.0 23.9 17.7 9.8 14.4 5.6 22.1 8.0 27.8 19.9 5.5 24.6 16.6 6.8 7.1 11.7 31.4 10.8 9.9 70.6 22.1 7.2 23.5 20.7 13.9 12.2 9.3 11.1 13.5 8.7 9.2 5.4 18.7 6.6 13.2 15.5 32.2 7.0 27.7 8.1 5.7 10.7 11.8 10.7 18.2 12.5 9.4 0.0 4.0 6.8 2.7 7.3 9.3 15.8 10.8 10.3 10.0 13.7 13.3 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BEGAIN KIAA1446 ENSG00000183092 "Brain enriched guanylate kinase associated" Q9BUH8 14 100537147-100587413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2;pancreas: 23.8;pituitary gland: 19.6" "Cell type enriched" "Detected in many" 7 "Horizontal cells: 143.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Group enriched" "Detected in some" 7 "HeLa: 56.6;SH-SY5Y: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002899 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Golgi apparatus, Cytosol" "HPA002899: AB_1078277" "unprognostic (2.98e-4)" "unprognostic (2.75e-3)" "unprognostic (2.66e-2)" "unprognostic (2.66e-4)" "unprognostic (2.77e-3)" "unprognostic (1.93e-2)" "unprognostic (5.16e-2)" "unprognostic (6.35e-2)" "unprognostic (3.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.15e-2)" "unprognostic (5.47e-2)" "unprognostic (1.59e-1)" "unprognostic (9.01e-2)" "unprognostic (3.11e-1)" "unprognostic (2.75e-1)" "unprognostic (2.60e-1)" 1.9 3.2 15.3 0.4 14.9 4.0 1.7 16.4 27.2 3.4 0.0 1.2 2.6 2.4 0.8 1.0 6.0 1.2 2.6 22.0 5.1 1.0 0.7 1.4 0.5 6.4 1.5 4.8 23.8 4.6 19.6 1.6 6.6 4.1 0.2 2.1 1.5 1.3 0.7 1.2 2.7 0.8 1.0 5.8 1.2 2.8 3.2 1.0 1.0 0.1 0.5 1.5 1.3 11.9 0.8 3.3 1.8 11.1 0.0 0.0 0.3 0.3 0.0 0.5 0.1 0.0 1.1 0.3 0.5 0.5 2.5 0.4 0.5 0.0 0.0 0.0 1.1 5.1 56.6 0.0 0.1 0.2 0.3 0.3 0.2 0.9 1.2 0.0 0.1 0.7 0.6 0.1 0.0 4.4 0.4 1.6 1.3 0.3 1.9 0.1 0.3 7.0 0.0 0.2 2.9 129.7 3.0 0.1 3.0 0.0 0.9 13.7 0.0 0.4 3.8 0.1 0.0 0.0 0.0 0.2 9.2 2.5 0.3 0.8 0.1 3.4 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.0 0.1 15.3 14.9 16.4 27.2 22.0 5.1 6.4 1.5 6.6 1.0 3.2 11.9 0.8 0.0 0.6 18.6 0.3 2.4 1.8 0.3 0.0 3.7 0.5 1.1 2.3 0.0 0.7 0.0 0.0 0.1 0.2 0.3 0.0 1.4 0.4 0.1 0.1 0.6 0.0 0.0 18.4 8.0 0.2 1.5 0.0 0.1 9.5 0.1 1.4 0.0 0.3 143.0 10.9 0.0 0.0 0.0 0.8 0.8 1.8 0.3 1.8 4.7 1.1 0.8 0.0 15.6 0.8 2.9 1.1 6.8 0.3 1.6 2.7 0.1 0.1 2.3 0.0 1.7 0.7 0.9 1.5 0.3 2.0 0.1 0.3 0.4 0.4 0.4 BEND4 "CCDC4, FLJ35632, FLJ43965" ENSG00000188848 "BEN domain containing 4" Q6ZU67 4 42110853-42152878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;prostate: 3.3;testis: 9.4" "Cell type enhanced" "Detected in some" "B-cells: 8.1;Inhibitory neurons: 6.2;Muller glia cells: 10.7;Spermatogonia: 38.3" "Group enriched" "Detected in some" 43 "prostate cancer: 6.3;testis cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 33.2;HEK 293: 7.9;HEL: 21.1;MOLT-4: 13.1;SuSa: 15.4;U-698: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036850 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA036850: AB_10600787" "unprognostic (3.62e-4)" "unprognostic (3.82e-1)" "unprognostic (4.82e-2)" "unprognostic (5.96e-3)" "unprognostic (2.97e-3)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (5.58e-2)" "unprognostic (6.71e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (1.49e-1)" "unprognostic (4.58e-3)" "unprognostic (4.24e-1)" 0.0 0.0 0.7 1.1 0.7 0.8 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.3 1.1 0.0 0.1 0.2 2.1 1.2 3.6 0.1 0.0 0.0 1.0 0.3 2.8 3.3 0.2 1.1 0.0 0.0 0.0 0.0 1.2 0.1 0.1 1.2 0.2 9.4 0.7 1.1 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 33.2 0.0 0.0 0.0 7.9 21.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.0 7.0 0.0 0.1 0.0 0.0 13.1 0.0 6.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 0.8 0.0 0.0 0.0 15.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 1.3 1.3 1.1 1.2 3.6 2.8 0.1 0.7 0.4 0.4 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 0.0 3.4 4.4 0.0 0.0 0.3 0.0 0.0 0.0 4.8 2.5 0.0 0.0 3.3 6.2 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.1 10.7 0.0 3.5 0.2 0.0 0.0 0.0 3.9 1.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.6 38.3 0.0 0.0 0.0 1.5 2.2 0.0 0.0 BEND7 "C10orf30, FLJ40283" ENSG00000165626 "BEN domain containing 7" Q8N7W2 10 13438484-13528974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 167.3;Late spermatids: 268.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.5;hTERT-RPE1: 17.3" HPA037835 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli fibrillar center, Vesicles" "HPA037835: AB_10669722" "unprognostic (6.22e-2)" "unprognostic (1.80e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-2)" "unprognostic (1.18e-2)" "unprognostic (4.62e-3)" "unprognostic (3.24e-3)" "unprognostic (3.52e-2)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (4.19e-3)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (1.58e-1)" "unprognostic (5.20e-3)" 8.0 6.0 4.7 2.4 4.9 0.7 9.4 6.5 4.7 7.4 4.9 11.2 16.5 7.3 13.6 2.2 12.4 6.5 7.4 5.0 4.9 18.5 9.0 9.1 1.1 5.1 5.9 8.3 12.1 14.8 10.3 4.3 5.9 5.7 6.6 15.4 15.1 6.5 16.4 3.2 19.3 6.1 4.7 3.0 11.2 16.3 5.6 0.5 23.5 13.3 1.0 6.8 4.4 4.4 9.9 5.9 6.0 2.2 0.1 0.0 8.7 3.8 0.1 9.3 5.6 2.4 17.5 0.0 5.1 7.3 5.2 0.4 9.8 2.1 8.3 0.0 8.7 0.0 0.0 11.4 3.9 0.0 0.0 0.2 5.7 1.2 0.0 17.3 10.3 1.4 4.3 0.0 9.3 4.0 0.1 0.0 1.8 0.0 1.0 0.0 4.4 0.0 8.0 1.3 0.4 4.7 10.7 0.0 0.1 9.1 0.1 4.7 9.2 1.1 13.8 11.6 4.8 0.0 0.0 0.0 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.7 4.9 6.5 4.7 5.0 4.9 5.1 5.9 5.9 4.7 5.6 4.4 33.6 22.4 11.6 23.5 1.9 3.4 23.6 1.1 1.8 14.4 15.4 11.4 11.0 22.8 9.8 20.2 8.4 3.0 2.6 13.2 3.9 13.0 167.3 25.0 5.8 16.7 7.8 0.0 7.5 16.5 2.9 8.0 9.7 36.2 6.3 14.7 22.5 9.6 3.0 1.7 10.2 8.5 6.1 9.4 1.9 268.7 5.0 2.5 3.6 24.4 4.5 20.3 12.3 47.7 0.7 21.8 9.5 6.0 0.5 23.9 45.2 52.0 9.7 32.2 0.0 14.1 8.4 21.5 20.0 3.3 1.8 2.5 3.5 3.4 10.3 36.1 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 23.2" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "THP-1: 78.4" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: AB_2685195, HPA064872: AB_2685377, HPA067500: AB_2685855" "unprognostic (9.17e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-2)" "unprognostic (2.28e-5)" "unprognostic (7.22e-3)" "unprognostic (6.47e-4)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.52e-1)" "unprognostic (3.71e-2)" "unprognostic (2.86e-7)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (6.72e-3)" "unprognostic (1.86e-1)" 2.0 0.5 8.9 1.4 6.6 0.0 1.5 12.1 22.4 2.3 0.4 1.3 0.4 0.3 0.1 0.9 0.8 0.4 0.3 23.2 1.5 0.2 0.5 2.0 0.7 5.5 1.5 0.2 0.7 0.1 1.4 0.0 2.6 0.4 0.5 4.4 0.5 2.3 0.1 0.8 1.4 0.4 1.4 1.4 0.5 0.2 1.1 0.3 0.7 0.0 0.6 1.2 2.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.6 12.1 22.4 23.2 1.5 5.5 1.5 2.6 1.4 1.1 1.8 0.3 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 64.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 3.4 0.2 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 2.9 0.0 0.4 0.1 1.6 0.0 0.1 0.0 0.0 0.0 BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" 15.4 10.6 11.4 13.5 10.0 12.0 10.9 10.9 10.5 20.8 7.8 18.5 4.6 15.5 6.0 47.0 12.8 9.4 19.8 11.1 8.6 9.1 8.5 16.0 14.7 11.0 9.8 12.5 8.9 17.7 6.0 10.4 10.3 11.3 5.0 6.5 14.6 13.1 22.3 63.4 10.4 13.7 10.5 17.3 9.5 9.4 10.0 13.8 10.0 15.3 16.8 15.2 30.9 12.3 32.6 26.5 19.2 19.8 36.6 25.1 27.1 30.8 22.2 17.2 13.6 15.6 14.4 36.3 19.5 34.4 22.0 99.4 21.8 49.1 19.4 17.4 23.5 19.2 25.6 21.7 21.8 26.9 30.0 25.8 67.1 28.8 22.0 20.4 26.0 15.4 19.3 27.5 38.1 21.4 25.6 16.7 13.3 23.8 32.0 27.8 41.8 19.3 27.8 27.0 13.4 20.7 21.7 19.9 14.3 19.2 8.2 12.3 34.9 31.8 21.1 53.9 33.9 22.5 17.5 31.9 26.9 16.3 28.4 1.6 3.4 4.4 1.2 3.6 1.2 1.8 1.4 1.6 3.8 2.0 1.3 1.2 7.5 1.1 5.9 3.2 0.9 1.7 11.4 10.0 10.9 10.5 11.1 8.6 11.0 9.8 10.3 10.5 10.0 12.3 21.7 28.9 12.7 14.7 27.6 73.7 17.1 19.2 83.6 12.8 11.4 10.2 54.5 8.6 16.2 7.3 6.2 8.5 26.1 3.4 3.9 10.1 6.5 21.3 26.7 26.4 10.8 16.0 16.2 5.1 6.5 26.0 5.6 21.1 24.1 13.0 19.2 7.5 14.2 15.2 14.0 1.9 12.2 32.4 30.2 7.6 21.1 40.7 16.0 19.7 38.9 22.0 7.2 9.5 18.5 8.5 3.6 33.4 22.1 18.7 0.8 6.7 14.0 6.4 19.7 23.0 33.1 9.7 8.4 103.2 130.8 7.3 17.2 13.8 3.6 20.3 BICDL1 "BICDR-1, CCDC64, FLJ26450" ENSG00000135127 "BICD family like cargo adaptor 1" Q6ZP65 12 119989869-120094494 "Predicted intracellular proteins" "Neurogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 128.7;pituitary gland: 80.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 12.9;dendritic cells: 13.7;Distal tubular cells: 23.5;Plasma cells: 12.8;Proximal tubular cells: 27.3;T-cells: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 48.9;MCF7: 27.7;OE19: 25.2;SCLC-21H: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061116 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" Vesicles "HPA061116: AB_2684433" "unprognostic (2.17e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.68e-3)" "unprognostic (3.05e-2)" "unprognostic (6.81e-4)" "prognostic favorable (3.15e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (5.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.63e-2)" "unprognostic (3.31e-3)" "unprognostic (7.26e-2)" "prognostic favorable (3.93e-5)" "prognostic favorable (1.21e-5)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.15e-1)" 24.8 2.7 7.6 10.8 8.8 3.0 2.9 5.4 13.3 7.4 0.2 3.2 4.0 0.7 37.5 35.8 4.2 4.1 2.9 7.6 10.9 128.7 5.6 6.0 23.8 5.6 3.4 1.1 7.7 2.5 80.2 1.1 5.6 4.9 3.1 67.6 8.3 1.0 0.4 64.2 7.3 0.6 2.6 7.1 20.9 40.8 6.9 18.2 24.4 0.0 15.5 3.1 21.5 6.6 3.5 10.6 0.6 0.0 0.9 0.0 12.6 0.0 0.0 0.0 0.0 9.5 5.9 16.8 4.4 0.0 9.1 7.9 1.3 1.6 0.0 1.2 1.7 0.1 4.7 18.3 0.0 2.1 17.1 0.0 48.9 0.0 0.6 0.0 0.0 14.1 0.5 2.1 0.0 27.7 12.3 0.2 21.1 25.2 5.0 1.3 0.9 4.5 6.2 8.4 30.8 2.2 3.6 9.7 2.6 5.1 22.4 8.3 0.0 0.1 2.9 0.0 0.2 4.2 17.1 6.5 0.6 2.4 1.7 0.3 0.0 0.0 1.2 0.0 0.4 0.1 1.2 1.0 0.0 0.1 0.9 0.7 0.0 0.0 0.3 0.0 0.2 0.2 7.6 8.8 5.4 13.3 7.6 10.9 5.6 3.4 5.6 2.6 6.9 6.6 0.6 0.0 1.3 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.8 2.2 0.0 0.0 1.3 12.9 0.0 1.0 13.7 0.0 23.5 1.1 0.0 3.1 1.0 0.1 0.0 0.0 0.0 3.5 0.6 2.7 0.0 7.7 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.9 0.0 0.0 12.8 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 17.6 0.7 0.0 0.0 BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.8;pancreas: 127.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 52.2;Breast myoepithelial cells: 22.1;Ductal cells: 34.3;Endometrial ciliated cells: 28.9;Exocrine glandular cells: 49.8;Glandular and luminal cells: 28.3;Pancreatic endocrine cells: 35.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;BEWO: 15.4;CAPAN-2: 14.4;HaCaT: 22.5;MCF7: 22.8;RT4: 10.8;SK-BR-3: 11.0;T-47d: 14.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 2.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: AB_10794925" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (6.06e-3)" "unprognostic (9.65e-5)" "unprognostic (5.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (8.56e-2)" "unprognostic (2.55e-2)" "unprognostic (2.38e-1)" "unprognostic (4.32e-2)" "prognostic favorable (9.04e-4)" 0.4 0.0 0.2 1.9 0.2 0.0 8.6 0.4 0.4 20.7 0.1 25.1 10.4 0.7 2.6 104.8 6.0 3.4 0.0 0.2 0.1 5.8 0.9 5.9 0.0 0.6 0.3 0.1 127.2 4.1 1.5 0.3 0.8 16.8 6.4 0.0 44.4 3.2 0.6 43.8 13.5 0.2 0.2 0.2 21.5 0.1 0.3 0.2 6.1 0.0 3.1 11.4 44.3 0.2 9.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 2.6 14.4 0.0 0.0 0.0 0.0 22.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 6.4 0.0 0.1 0.0 0.2 0.0 10.8 0.2 0.1 0.0 11.0 0.0 0.3 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.4 0.2 0.1 0.6 0.3 0.8 0.2 0.3 0.2 0.3 12.8 18.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 52.2 22.1 0.0 0.0 12.4 16.5 0.0 4.5 1.3 0.0 3.9 34.3 0.0 28.9 2.8 0.5 0.0 0.0 0.0 49.8 6.1 0.6 0.0 28.3 2.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.6 0.3 0.0 0.0 BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: AB_1846746" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (9.52e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.05e-2)" "unprognostic (3.02e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (5.00e-2)" "unprognostic (1.64e-2)" 23.2 27.6 18.4 25.8 19.6 36.4 28.2 20.0 23.4 27.5 22.5 27.2 23.6 25.7 30.2 18.1 19.7 24.8 23.6 17.9 19.9 28.8 44.3 22.6 34.5 19.7 19.4 21.8 33.7 20.4 18.8 29.4 19.8 21.4 26.0 22.2 21.1 16.1 29.7 18.2 25.2 21.6 20.1 26.7 23.5 24.6 18.8 50.6 22.2 32.9 27.1 30.4 20.4 24.9 34.0 24.7 37.3 29.3 46.1 63.3 23.9 128.3 48.8 71.9 43.4 30.9 81.7 37.1 123.5 59.2 40.3 36.7 24.5 33.8 85.7 50.0 12.6 37.2 17.6 37.8 46.9 22.9 23.0 40.8 64.4 41.2 52.3 66.2 50.1 22.2 34.4 0.2 131.0 10.9 24.3 20.1 18.1 40.1 23.7 11.9 48.4 24.9 55.4 38.5 15.5 20.3 44.7 26.9 40.7 56.7 42.5 27.3 82.7 150.7 34.4 46.2 84.2 14.9 21.9 25.0 32.6 28.2 112.5 97.2 43.3 104.4 22.9 42.2 18.9 15.7 21.5 21.3 33.8 15.1 27.4 27.7 67.6 34.3 46.7 20.4 33.2 27.5 18.4 19.6 20.0 23.4 17.9 19.9 19.7 19.4 19.8 20.1 18.8 24.9 61.8 41.7 41.1 17.0 52.6 67.2 109.2 53.6 39.9 24.4 52.3 52.8 58.6 67.2 49.5 64.4 29.2 38.4 77.9 85.7 43.0 49.8 20.8 63.2 54.0 51.0 48.5 80.0 22.4 73.7 27.8 55.9 28.5 85.7 62.7 43.7 59.3 182.1 41.5 20.2 21.7 54.3 46.8 84.3 71.5 11.2 36.4 71.1 51.6 26.2 81.2 34.3 55.6 21.6 33.1 54.5 71.1 29.0 49.2 75.0 82.1 110.1 56.6 31.0 26.3 45.7 48.9 44.7 42.4 28.4 62.8 35.2 57.1 36.4 44.2 82.5 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 BIRC7 "KIAP, ML-IAP, mliap, RNF50" ENSG00000101197 "Baculoviral IAP repeat containing 7" Q96CA5 20 63235883-63240495 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 6.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.4;Extravillous trophoblasts: 16.5;Hofbauer cells: 75.8;Melanocytes: 26.6;Muller glia cells: 54.2" "Cancer enriched" "Detected in many" 10 "melanoma: 73.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 196.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA047850, HPA061283" Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Centrosome, Cytosol" "HPA047850: AB_2680181, HPA061283: " "unprognostic (3.60e-1)" "unprognostic (7.94e-2)" "unprognostic (2.70e-2)" "unprognostic (1.78e-3)" "unprognostic (1.15e-1)" "unprognostic (8.11e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.62e-3)" "unprognostic (1.24e-2)" "unprognostic (6.90e-2)" "unprognostic (2.27e-1)" "unprognostic (8.82e-3)" "unprognostic (1.22e-2)" "unprognostic (4.77e-2)" "unprognostic (2.55e-2)" "unprognostic (4.84e-2)" 0.8 0.8 0.7 0.3 0.4 0.1 0.4 0.3 1.3 1.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.7 0.9 0.9 0.3 1.1 1.3 0.8 0.7 0.1 0.0 0.0 0.3 6.5 1.1 0.1 0.0 0.6 0.2 0.0 0.0 2.4 0.2 0.0 0.7 0.9 0.1 0.1 1.2 0.0 0.2 0.0 0.2 0.2 0.7 1.5 0.3 4.3 0.1 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 6.6 1.1 0.0 17.8 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 20.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 196.8 4.4 1.3 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.3 1.3 0.7 0.9 0.8 0.7 1.1 0.7 1.2 1.5 0.3 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 1.8 0.0 12.4 0.1 0.0 0.0 0.7 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.6 16.5 0.7 0.0 0.0 2.5 0.1 0.0 0.0 75.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.7 26.6 0.0 0.0 54.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248203-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 130.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 42000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: AB_10805479, HPA064307: AB_2685241" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (2.54e-2)" "unprognostic (3.91e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (6.69e-3)" "unprognostic (1.95e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" 20.6 13.5 13.4 18.2 15.0 18.1 20.4 15.9 17.6 19.1 14.5 18.8 12.4 21.2 21.1 28.3 14.7 18.4 15.6 13.5 15.2 22.0 14.0 16.0 26.0 15.6 14.1 13.9 26.8 21.7 9.7 27.4 15.4 14.4 15.4 14.7 15.6 14.4 28.8 130.3 18.3 22.4 14.7 20.6 16.2 15.9 14.2 36.3 16.5 19.0 26.9 17.9 21.5 16.2 40.3 62.9 61.5 41.6 40.6 43.8 27.8 36.5 24.0 59.1 50.8 93.2 11.9 119.5 63.3 31.1 26.1 27.1 135.5 52.8 50.1 31.5 101.4 73.5 54.6 80.0 58.3 136.1 43.2 50.5 3.5 46.5 26.5 47.1 87.2 98.2 157.9 47.6 24.6 31.0 168.1 98.6 57.2 0.0 29.2 143.0 154.5 78.9 46.8 35.6 135.1 48.4 32.6 63.2 42.2 106.6 42.9 68.5 54.5 35.0 69.2 16.0 66.0 55.8 124.1 159.3 26.7 0.2 47.6 0.0 8.8 1.5 15.3 6.2 25.3 6.5 18.2 20.2 10.1 7.3 16.4 17.8 1.2 16.3 3.3 10.1 20.0 9.9 13.4 15.0 15.9 17.6 13.5 15.2 15.6 14.1 15.4 14.7 14.2 16.2 21.0 3.2 12.6 13.4 8.8 15.9 16.7 10.6 19.4 20.2 10.3 6.6 17.8 12.8 4.0 11.0 12.5 49.6 15.6 7.6 7.9 17.4 8.4 7.4 28.2 24.0 18.0 22.5 19.0 14.2 38.0 18.3 11.2 7.0 43.8 30.5 25.7 6.9 25.0 13.5 20.9 8.4 6.1 18.9 7.1 6.6 16.1 13.0 10.6 18.7 12.2 9.9 22.6 29.1 22.6 7.2 9.6 24.8 20.0 13.0 11.5 20.0 5.5 15.7 6.6 12.9 19.7 14.9 29.1 24.0 12.6 27.5 20.9 34.8 11.5 7.6 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 625.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 465.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.3;monocytes: 465.2" "Cell line enhanced" "Detected in many" "A549: 506.6;K-562: 506.8;OE19: 451.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 115.7 76.8 46.6 48.2 46.9 625.2 93.8 49.4 61.0 86.2 52.1 78.5 75.1 59.0 20.5 188.8 69.3 50.9 125.6 44.5 48.0 103.1 266.2 102.8 58.9 56.0 48.6 66.7 73.2 46.1 25.2 52.1 58.5 74.3 30.3 5.5 89.4 42.2 210.4 83.9 72.2 31.7 49.8 166.7 138.4 10.2 52.3 27.5 64.5 94.1 25.3 81.0 96.5 53.4 227.9 506.6 7.3 77.7 73.7 70.2 57.3 28.0 88.7 39.3 75.4 103.4 203.8 74.3 212.3 56.3 126.8 73.1 30.4 64.6 10.5 123.8 20.0 114.9 73.4 62.4 169.8 1.6 32.2 69.2 119.4 52.4 34.2 40.1 41.8 27.4 506.8 137.0 51.0 359.2 6.1 7.2 1.9 451.4 133.8 54.0 23.4 120.3 50.9 146.5 0.4 10.5 84.5 224.5 84.4 13.2 221.5 17.6 39.2 99.4 103.9 156.4 15.9 71.7 92.1 28.5 259.1 46.2 39.0 45.5 465.2 18.0 29.2 220.9 27.0 58.2 24.3 24.5 343.3 37.5 24.7 19.3 58.4 27.4 117.7 75.8 37.3 259.4 46.6 46.9 49.4 61.0 44.5 48.0 56.0 48.6 58.5 49.8 52.3 53.4 74.6 221.2 164.5 9.4 34.4 129.4 348.5 337.9 103.6 11.2 93.8 143.0 130.5 164.5 184.2 97.5 6.2 84.9 39.5 343.6 266.1 234.2 10.0 56.5 46.3 51.1 44.9 3131.8 5.2 267.3 94.7 112.5 280.3 83.1 43.1 31.0 57.1 680.8 1099.2 10.1 5.1 223.5 158.7 627.7 165.4 23.6 124.2 286.7 144.1 13.1 219.8 88.0 32.0 2.0 5.6 260.4 464.0 94.0 25.7 229.7 864.3 488.3 139.1 13.5 32.9 65.4 146.0 2.6 4.0 160.3 130.4 74.7 34.5 34.7 191.0 260.5 BMI1 "PCGF4, RNF51" ENSG00000168283 "BMI1 proto-oncogene, polycomb ring finger" P35226 10 22321099-22331484 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 134.0;Late spermatids: 165.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 508.3;U-937: 583.9" "CAB011120, HPA030471, HPA030472" Supported Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Nucleoli, Cytosol" "CAB011120: , HPA030471: AB_2673491, HPA030472: AB_10601090" "unprognostic (5.44e-1)" "unprognostic (2.98e-1)" "unprognostic (4.24e-2)" "unprognostic (4.37e-2)" "unprognostic (2.76e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (2.60e-8)" "unprognostic (9.43e-2)" "unprognostic (7.95e-2)" "unprognostic (7.84e-2)" "unprognostic (8.23e-2)" "unprognostic (1.56e-1)" "unprognostic (7.44e-2)" "unprognostic (9.73e-2)" "unprognostic (8.56e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-2)" 29.0 31.1 26.6 25.1 35.1 21.9 36.0 29.9 42.4 27.6 28.2 26.2 19.7 30.7 29.7 21.9 22.6 23.9 20.5 25.0 27.8 26.0 35.6 23.4 27.7 29.5 30.1 21.7 25.7 56.9 25.0 28.7 31.6 33.7 21.5 40.4 19.9 26.1 44.4 14.4 20.8 36.2 29.9 36.2 22.5 35.3 28.1 24.9 23.9 35.5 27.0 23.8 14.8 45.4 74.9 36.1 41.2 12.7 68.9 54.6 40.5 49.7 22.2 37.3 43.5 37.6 93.4 38.1 32.8 45.6 42.2 26.1 59.1 35.0 45.4 508.3 72.8 104.7 28.7 42.9 41.1 39.8 55.7 35.5 58.8 41.2 45.3 47.0 26.2 62.1 105.4 63.3 48.6 30.2 106.9 11.4 9.3 36.3 83.4 79.6 57.1 37.3 35.3 25.2 33.8 66.0 32.7 42.5 57.3 17.8 38.5 153.8 56.4 41.4 122.6 99.6 67.6 76.1 110.8 83.1 59.5 583.9 27.4 15.1 1.3 2.5 5.2 3.0 7.0 4.4 5.3 5.0 0.9 2.2 4.4 4.3 0.6 5.2 2.1 1.6 4.1 2.0 26.6 35.1 29.9 42.4 25.0 27.8 29.5 30.1 31.6 29.9 28.1 45.4 18.9 25.6 24.0 0.0 23.1 15.9 20.5 12.4 22.8 20.9 24.4 20.3 19.0 22.8 19.8 12.9 8.4 12.7 14.2 5.6 13.7 16.3 134.0 12.1 25.3 24.0 13.2 19.1 0.0 18.2 22.2 19.8 7.7 9.8 12.0 12.6 28.5 30.7 9.9 30.3 0.0 9.9 14.2 19.7 25.6 165.1 36.1 13.8 37.4 0.0 17.5 13.9 15.5 0.0 0.0 22.9 7.3 36.5 33.9 29.1 4.6 13.0 16.9 15.2 19.7 26.5 28.6 19.8 22.2 11.2 14.6 6.7 22.4 17.0 10.3 20.4 BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;choroid plexus: 43.8;thyroid gland: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Basal squamous epithelial cells: 51.8;Cytotrophoblasts: 137.4;Oligodendrocyte precursor cells: 74.4;Squamous epithelial cells: 44.2;Syncytiotrophoblasts: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 172.1;MCF7: 202.3;OE19: 94.4;RPMI-8226: 77.8;SK-BR-3: 128.4;U-698: 237.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057757 Approved Nucleoplasm,Nucleoli,Vesicles "Secreted to blood" NA NA 248000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA057757: AB_2683518" "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" 1.5 6.5 33.1 1.9 34.6 0.0 1.3 37.2 27.9 8.5 43.8 2.9 2.2 1.2 17.2 23.9 9.5 0.4 13.8 35.6 28.5 6.3 0.0 1.6 1.0 36.2 36.3 0.2 0.5 0.0 2.7 25.7 34.7 5.9 1.7 5.3 3.9 9.2 0.3 22.5 1.9 0.3 32.8 0.6 3.6 0.7 39.7 3.8 45.9 0.0 2.1 6.8 13.0 42.8 0.3 0.7 23.4 5.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 20.0 6.8 172.1 41.3 0.0 8.7 48.3 5.2 0.0 0.0 0.4 17.2 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 202.3 0.0 0.1 12.3 94.4 0.0 0.1 0.1 77.8 0.0 0.2 0.4 17.8 5.5 128.4 0.5 15.2 0.9 0.4 0.4 0.1 10.9 0.0 0.1 0.2 0.3 237.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 34.6 37.2 27.9 35.6 28.5 36.2 36.3 34.7 32.8 39.7 42.8 0.6 6.4 2.2 74.1 0.4 13.8 13.4 12.9 51.8 4.7 0.9 4.6 15.1 0.0 4.2 1.8 0.0 137.4 0.1 0.2 0.0 0.0 5.3 1.7 2.4 1.2 2.4 0.0 0.9 0.0 21.0 13.5 2.0 2.5 21.6 0.1 0.0 0.0 11.0 1.7 4.7 1.5 6.1 0.0 1.9 4.9 0.3 0.4 3.6 2.8 0.1 38.4 0.0 74.4 8.7 0.0 0.3 0.4 2.5 6.6 0.2 2.2 1.9 2.4 0.0 1.3 0.8 1.8 3.4 44.2 9.7 56.9 0.9 0.7 1.5 18.1 BMS1 "BMS1L, KIAA0187" ENSG00000165733 "BMS1 ribosome biogenesis factor" Q14692 10 42782795-42834937 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036589, HPA043081" Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Mitotic chromosome" "HPA036589: AB_10601460, HPA043081: AB_2678305" "unprognostic (1.46e-2)" "unprognostic (4.31e-1)" "unprognostic (7.09e-2)" "unprognostic (3.56e-2)" "unprognostic (3.11e-2)" "unprognostic (7.25e-3)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (3.81e-3)" "unprognostic (1.32e-2)" "unprognostic (2.16e-3)" "unprognostic (7.03e-2)" "unprognostic (1.80e-1)" "unprognostic (3.43e-1)" "unprognostic (4.82e-2)" 8.1 8.3 6.5 8.9 7.2 10.7 8.5 8.6 8.2 8.2 8.5 7.7 6.3 8.2 6.8 9.6 7.3 5.1 9.0 6.1 7.8 8.1 8.1 7.6 10.0 7.4 7.8 8.4 8.8 11.4 7.6 8.2 7.7 7.3 7.9 6.5 8.8 6.9 17.7 10.2 7.8 7.7 6.5 8.7 7.4 8.1 7.0 9.6 7.2 13.4 10.8 10.1 8.3 7.2 32.0 26.7 25.3 29.0 18.8 15.5 24.5 26.1 27.5 30.3 25.9 37.1 24.4 16.9 18.1 22.7 17.0 27.3 42.0 33.8 39.4 24.7 29.3 22.7 20.7 31.9 16.2 61.7 20.4 13.9 16.9 32.7 31.5 16.9 23.2 19.4 40.4 17.7 21.8 27.1 34.6 20.3 32.3 22.0 28.0 31.3 26.7 18.1 16.8 27.7 19.3 20.4 22.9 25.1 21.7 26.2 30.6 17.6 28.3 14.0 50.7 28.4 43.2 14.1 18.7 48.5 20.5 44.9 11.0 3.8 4.6 2.7 7.2 8.2 8.5 8.7 8.9 7.9 7.5 6.1 9.6 8.3 0.6 6.1 7.1 3.9 6.9 5.3 6.5 7.2 8.6 8.2 6.1 7.8 7.4 7.8 7.7 6.5 7.0 7.2 25.6 32.1 33.1 19.6 29.7 22.9 33.9 28.4 14.2 20.7 18.8 17.1 48.0 20.0 37.4 23.9 10.4 27.7 23.6 10.2 21.5 32.3 14.6 28.8 34.5 31.3 16.8 19.5 31.4 34.9 30.0 26.4 16.3 30.0 22.1 36.8 21.4 18.6 19.7 21.9 28.8 11.5 22.4 15.3 22.6 12.1 23.6 19.9 33.8 10.3 35.2 12.8 24.7 20.1 24.0 38.2 8.9 16.6 31.3 32.2 8.8 30.1 49.5 28.7 19.7 35.3 31.4 40.3 56.1 17.1 25.4 24.9 25.3 33.5 18.7 41.4 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 173.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 313.2;Distal tubular cells: 352.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: AB_2682063" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (4.23e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.86e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (4.03e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (9.90e-5)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (4.40e-1)" 35.6 39.3 52.1 22.6 54.3 40.8 31.4 58.9 66.1 20.2 55.0 46.5 33.8 24.5 25.1 31.7 20.8 11.9 101.0 52.7 56.5 59.8 33.7 23.5 22.2 57.0 53.8 16.6 44.7 56.2 29.6 14.2 56.0 25.4 37.6 35.7 39.7 23.7 117.8 16.6 28.9 22.6 54.7 21.9 41.1 15.8 53.7 24.8 28.8 173.9 21.6 27.1 24.3 55.3 102.8 134.0 44.8 46.2 81.5 78.3 113.9 92.5 54.5 104.0 72.0 176.6 45.4 67.2 79.7 82.4 99.3 53.2 107.9 135.4 95.8 126.5 172.8 85.4 88.3 269.8 76.1 167.3 39.0 62.2 96.6 100.9 124.2 45.9 79.4 144.3 183.2 73.7 116.0 163.6 136.4 123.1 66.9 196.8 198.6 88.5 120.1 132.0 138.8 106.2 70.4 40.7 68.3 106.8 123.3 62.0 62.6 102.8 42.6 83.9 142.9 93.8 185.4 67.5 135.3 92.7 87.6 131.8 73.8 14.7 14.2 3.9 68.3 29.9 75.7 45.4 92.7 72.6 37.8 44.5 79.3 68.7 3.0 51.7 33.5 65.1 91.2 40.6 52.1 54.3 58.9 66.1 52.7 56.5 57.0 53.8 56.0 54.7 53.7 55.3 54.7 9.6 29.8 8.5 33.2 22.7 44.5 111.8 43.3 29.9 82.0 109.5 313.2 44.3 50.1 84.6 16.7 54.9 42.8 125.4 352.1 93.2 20.0 67.0 46.2 45.5 76.1 138.2 14.3 111.4 167.5 48.6 58.1 61.5 25.4 31.9 36.4 113.3 113.9 26.9 15.0 128.3 83.4 32.1 28.9 10.2 32.9 32.2 99.6 3.7 59.4 61.8 62.8 7.5 7.7 95.0 70.9 46.3 76.1 50.9 85.6 266.4 51.2 52.6 19.7 39.6 64.4 66.8 80.5 101.0 16.9 22.3 45.1 83.0 176.2 52.0 BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 223.5" "Low region specificity" "Detected in all" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: AB_2680193, HPA066764: AB_2685716" "unprognostic (6.92e-2)" "unprognostic (5.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.06e-3)" "unprognostic (3.32e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (3.35e-5)" "unprognostic (2.25e-2)" "unprognostic (4.14e-1)" "unprognostic (3.31e-1)" "unprognostic (2.26e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.23e-7)" "unprognostic (7.83e-2)" "unprognostic (4.33e-1)" "unprognostic (8.49e-2)" "unprognostic (4.06e-3)" 18.1 17.8 6.8 8.8 6.9 9.7 16.3 7.7 10.9 16.1 3.5 17.3 5.6 18.2 1.0 26.0 13.2 2.8 24.4 7.6 5.5 16.7 21.5 13.3 8.0 7.1 6.0 11.1 32.0 5.6 16.9 3.7 6.5 15.3 1.9 1.1 13.2 3.1 76.6 21.4 14.9 3.1 4.7 20.4 15.4 20.1 6.2 5.4 17.0 8.1 3.6 19.3 16.5 6.1 45.0 87.4 11.8 50.6 6.4 7.7 41.4 30.5 6.5 30.3 19.1 66.3 25.4 54.1 50.1 11.6 11.5 34.9 21.2 36.2 6.9 47.8 82.5 68.4 54.4 49.7 15.1 30.8 35.6 15.5 17.0 25.2 22.1 5.7 18.8 48.3 70.1 18.1 11.9 112.8 82.4 37.6 28.3 45.1 223.5 61.4 17.6 82.2 12.5 30.1 64.7 25.8 32.5 41.9 20.3 5.5 30.6 27.7 36.6 27.8 83.3 37.1 88.5 16.5 11.7 45.6 20.3 48.6 36.7 0.0 2.2 1.3 1.9 2.3 2.1 2.5 2.2 2.5 3.0 1.8 2.0 1.8 0.1 1.8 2.0 2.0 2.0 1.2 6.8 6.9 7.7 10.9 7.6 5.5 7.1 6.0 6.5 4.7 6.2 6.1 12.8 9.6 5.1 3.9 16.7 0.5 18.7 0.0 13.1 9.8 12.7 13.8 7.2 10.0 3.7 11.0 0.0 25.2 20.9 18.7 5.9 25.8 11.2 7.5 10.7 12.0 26.9 22.1 4.4 21.7 45.3 13.2 17.3 8.3 10.2 13.5 4.6 14.8 21.5 15.2 3.5 11.5 0.0 11.1 0.0 24.3 10.5 12.8 0.0 1.0 16.2 16.7 18.6 5.0 2.8 26.4 11.3 9.8 25.4 39.5 11.3 17.2 1.5 4.6 13.1 12.9 15.1 13.9 53.4 25.7 0.1 17.8 11.8 29.6 31.8 14.3 BORA "C13orf34, FLJ22624" ENSG00000136122 "BORA aurora kinase A activator" Q6PGQ7 13 72727749-72756198 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 13.5;Sertoli cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040866 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA040866: AB_10794868" "unprognostic (9.93e-2)" "unprognostic (7.18e-2)" "unprognostic (4.57e-2)" "unprognostic (7.09e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-4)" "unprognostic (2.65e-2)" "unprognostic (2.82e-3)" "unprognostic (6.18e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-2)" "unprognostic (5.32e-12)" "unprognostic (7.04e-3)" "unprognostic (2.88e-1)" "unprognostic (9.93e-2)" "unprognostic (2.28e-2)" 1.6 1.3 1.2 4.3 1.2 6.0 2.4 1.4 1.7 1.6 1.9 4.2 4.3 1.3 1.5 3.5 1.4 1.3 1.0 1.2 1.3 1.8 1.7 1.8 7.6 1.6 1.3 1.2 1.7 0.5 1.9 2.3 1.5 1.8 5.0 3.5 1.9 1.0 1.1 4.2 3.5 1.7 1.1 4.2 3.2 4.0 1.4 8.1 1.9 0.9 6.8 2.2 2.2 1.5 32.5 8.5 19.6 14.7 2.4 2.4 11.6 9.8 8.6 17.9 18.1 20.6 17.2 23.8 6.4 6.4 10.3 15.0 17.1 11.5 22.1 20.9 12.3 28.7 11.4 15.8 1.7 54.2 17.1 1.9 2.6 8.9 15.1 5.0 14.6 22.8 12.7 10.7 14.6 9.8 20.8 21.8 10.8 36.8 6.0 16.4 12.3 10.6 6.5 10.0 6.9 7.0 12.0 12.8 10.2 15.0 6.4 24.6 4.8 5.8 9.7 8.3 16.3 6.9 7.0 14.8 16.3 24.8 13.9 1.3 1.1 0.5 1.9 1.9 2.3 1.6 1.8 2.0 1.9 1.9 1.6 2.5 0.1 1.8 1.2 1.4 1.9 1.1 1.2 1.2 1.4 1.7 1.2 1.3 1.6 1.3 1.5 1.1 1.4 1.5 1.6 3.2 2.8 3.6 5.4 0.6 1.3 2.2 3.4 1.7 1.4 1.3 0.3 1.5 2.1 1.8 2.1 7.5 3.9 3.1 0.0 1.9 12.6 2.2 2.3 1.4 0.0 13.5 4.3 2.6 11.5 1.7 3.6 2.4 1.3 5.1 1.8 0.4 4.6 8.4 3.1 2.7 0.0 2.8 1.5 2.7 0.9 2.8 0.0 3.7 3.5 1.1 4.1 2.5 7.3 1.7 2.2 1.2 5.2 1.2 3.2 0.8 2.7 2.3 13.1 1.6 1.5 11.8 4.3 3.4 1.1 2.9 4.1 1.5 5.8 1.4 BORCS8-MEF2B MEF2BNB-MEF2B ENSG00000064489 "BORCS8-MEF2B readthrough" 19 19145569-19192158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.2;dendritic cells: 1.4;Gastric mucus-secreting cells: 1.5;Late spermatids: 1.1;Plasma cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 2.0;U-266/70: 3.1" HPA004734 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA004734: AB_10963939" "unprognostic (2.74e-1)" "unprognostic (5.77e-3)" "unprognostic (8.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.46e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.98e-1)" "unprognostic (3.75e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (6.23e-2)" "unprognostic (1.25e-1)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "unprognostic (5.29e-2)" 0.2 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.6 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.6 0.2 0.2 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.0 0.6 0.2 0.2 0.1 0.3 0.2 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.8 0.0 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.3 0.4 0.0 1.4 0.3 0.1 0.0 0.5 0.5 0.2 0.1 0.2 0.1 0.5 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.9 0.1 2.0 0.5 0.2 1.3 0.1 0.6 0.0 0.7 0.7 0.1 0.0 0.1 1.6 0.1 0.5 1.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.0 1.5 0.0 3.1 0.6 1.7 0.3 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.1 1.4 0.8 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.2 0.1 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.5 0.0 1.2 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.6 0.0 BPGM ENSG00000172331 "Bisphosphoglycerate mutase" P07738 7 134646811-134679816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Congenital erythrocytosis, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 87.3" "Group enriched" "Detected in all" 4 "Distal tubular cells: 129.1;Erythroid cells: 456.6;Syncytiotrophoblasts: 368.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 118.2;RT4: 186.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016493, HPA028735" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 81000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA016493: AB_1845414, HPA028735: AB_10600791" "unprognostic (2.56e-1)" "prognostic favorable (7.95e-4)" "unprognostic (3.19e-1)" "unprognostic (3.94e-1)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (3.81e-3)" "unprognostic (1.96e-1)" "unprognostic (7.74e-2)" "unprognostic (4.67e-3)" "unprognostic (7.42e-2)" "unprognostic (5.69e-2)" "prognostic favorable (1.54e-8)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.78e-2)" 11.4 12.6 16.3 9.1 17.1 87.3 12.4 17.9 20.5 12.5 15.8 12.9 8.4 9.6 18.5 26.9 8.5 12.9 13.5 16.5 19.0 35.1 13.1 14.0 11.1 17.9 17.8 7.1 8.4 35.3 18.1 47.0 18.2 13.5 10.0 19.9 17.8 17.9 37.8 10.7 8.0 12.1 19.6 12.5 11.9 14.7 17.7 16.3 11.9 27.0 26.2 39.0 17.2 18.5 14.0 16.3 21.7 29.6 24.3 14.4 21.9 41.3 49.9 15.7 23.2 6.5 18.5 17.1 12.0 23.2 30.9 11.2 23.3 22.7 27.6 118.2 19.9 9.8 15.4 7.8 16.7 18.8 12.4 14.2 20.0 29.7 16.0 24.0 58.0 20.8 28.8 20.9 37.8 6.6 30.7 26.0 22.7 27.7 15.3 23.2 15.5 12.4 36.1 186.8 18.7 31.1 19.3 23.1 21.7 23.1 15.1 11.8 44.7 25.1 6.0 33.7 33.9 33.9 41.2 21.5 43.3 17.7 43.7 61.1 16.4 48.9 23.3 22.2 16.7 19.3 15.0 20.7 17.5 18.9 20.7 21.1 30.2 18.5 23.0 11.4 21.1 23.6 16.3 17.1 17.9 20.5 16.5 19.0 17.9 17.8 18.2 19.6 17.7 18.5 17.6 9.6 25.5 6.5 15.7 39.0 18.5 60.6 10.8 19.2 15.9 18.7 25.0 18.6 52.3 27.6 2.1 44.5 43.0 5.0 129.1 45.9 3.4 10.0 7.0 18.8 13.1 456.6 8.0 18.2 32.7 17.0 4.1 8.5 24.7 6.6 10.0 4.7 15.1 20.2 9.3 4.6 36.7 11.7 10.5 7.2 10.2 11.8 23.2 5.6 15.7 25.6 47.4 7.5 11.6 49.0 4.6 12.0 14.2 26.0 5.5 68.8 50.5 13.5 6.6 12.0 22.1 33.9 21.8 13.5 13.2 368.9 25.0 7.8 4.8 19.2 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 BROX "C1orf58, FLJ32421" ENSG00000162819 "BRO1 domain and CAAX motif containing" Q5VW32 1 222712553-222735196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031445 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 270000 "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA031445: AB_10602697" "unprognostic (1.27e-1)" "unprognostic (4.32e-1)" "unprognostic (3.43e-2)" "unprognostic (4.60e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-1)" "unprognostic (3.31e-2)" "unprognostic (2.83e-2)" "unprognostic (2.52e-2)" "unprognostic (6.72e-2)" "unprognostic (4.27e-2)" "unprognostic (2.53e-2)" "unprognostic (4.84e-2)" "unprognostic (1.09e-1)" "unprognostic (6.56e-2)" "unprognostic (1.83e-2)" "unprognostic (2.50e-2)" 17.4 14.5 19.3 18.1 21.9 40.8 23.3 21.0 21.6 17.5 14.1 25.9 21.6 17.3 15.3 27.7 18.5 19.2 16.5 16.6 20.7 22.3 16.9 20.1 19.0 23.2 18.2 21.6 14.8 26.2 8.9 20.5 23.3 17.3 24.9 16.3 16.6 17.8 26.7 23.2 27.5 17.7 22.7 20.9 24.9 12.8 20.2 14.4 26.5 20.5 22.1 16.4 13.5 33.6 56.6 34.2 20.1 17.5 28.6 30.2 38.8 38.2 47.6 30.6 34.8 19.0 71.6 18.7 44.1 47.2 16.5 48.2 22.9 36.5 46.1 23.2 20.4 28.2 34.8 19.2 32.2 32.2 25.4 26.8 34.8 38.4 44.8 34.5 28.3 11.9 43.0 24.8 38.0 17.4 13.7 16.7 25.3 46.0 39.8 14.4 61.2 42.3 36.3 55.6 22.5 35.3 41.7 46.3 28.8 18.9 57.1 32.5 40.7 42.1 23.9 43.6 43.5 18.4 33.8 16.7 34.0 26.8 39.0 75.4 28.0 36.6 21.3 42.1 24.1 15.9 27.0 21.8 26.1 14.4 17.8 22.6 52.7 28.4 44.1 14.4 27.2 18.6 19.3 21.9 21.0 21.6 16.6 20.7 23.2 18.2 23.3 22.7 20.2 33.6 35.7 73.7 46.5 15.7 30.4 48.6 32.3 32.2 27.3 16.3 42.1 23.9 35.9 30.0 38.3 51.5 8.4 29.7 49.1 56.2 56.7 40.0 20.8 43.2 30.9 29.0 31.8 73.0 17.1 32.5 32.6 29.7 35.7 54.2 16.4 26.3 31.8 28.4 36.6 35.3 20.1 50.1 32.6 65.5 33.1 23.7 24.2 50.8 49.8 12.2 52.4 31.0 42.2 25.1 27.3 54.5 44.6 32.0 23.2 47.8 48.4 58.8 67.8 20.8 52.6 27.4 26.8 29.9 27.4 40.4 46.7 51.6 40.5 35.1 41.0 56.4 BRWD1 "C21orf107, DCAF19, FLJ11315, N143, WDR9" ENSG00000185658 "Bromodomain and WD repeat domain containing 1" Q9NSI6 21 39184176-39321559 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030943, HPA030944, HPA030945, CAB034184" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli" Cytosol "CAB034184: AB_2243666, HPA030943: AB_2673666, HPA030944: AB_2673667, HPA030945: AB_10670161" "unprognostic (6.00e-2)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (8.39e-3)" "unprognostic (4.94e-2)" "unprognostic (5.01e-2)" "unprognostic (8.90e-2)" "unprognostic (2.26e-1)" "unprognostic (4.82e-3)" "unprognostic (5.45e-2)" "unprognostic (2.58e-3)" "unprognostic (6.48e-2)" "unprognostic (1.19e-1)" "unprognostic (3.88e-2)" "unprognostic (2.56e-2)" 13.6 18.8 35.7 10.2 37.5 18.6 17.5 40.9 37.3 12.9 27.2 12.5 9.7 14.5 22.6 11.9 13.1 11.0 15.5 37.6 32.9 15.7 25.8 13.2 15.7 23.4 27.5 17.7 19.9 13.1 13.3 17.4 24.8 14.3 12.3 38.6 11.7 11.5 21.9 14.6 11.4 11.1 27.2 10.9 12.1 21.0 40.4 14.9 19.7 24.0 15.0 12.5 12.5 34.4 19.3 7.8 18.6 9.5 10.4 17.2 17.9 11.0 12.7 8.5 9.7 7.1 12.5 59.8 11.0 15.0 9.9 9.1 17.5 12.3 12.9 14.8 14.2 40.9 13.6 12.3 13.7 23.4 11.1 11.2 19.0 11.2 29.0 18.1 11.9 38.7 32.4 30.7 11.5 13.4 15.8 26.8 19.5 23.1 10.7 28.5 14.4 19.4 9.5 12.2 13.9 18.0 23.8 25.0 15.7 6.2 20.7 31.8 14.3 10.6 5.2 6.2 8.1 32.7 24.5 30.1 12.5 24.3 8.7 3.5 4.2 9.7 8.0 5.0 6.1 7.3 6.8 8.3 5.8 4.8 8.2 6.8 4.3 8.4 3.1 5.4 8.5 3.4 35.7 37.5 40.9 37.3 37.6 32.9 23.4 27.5 24.8 27.2 40.4 34.4 42.5 48.1 49.9 147.6 46.1 63.2 43.8 26.6 52.9 65.5 43.2 24.9 59.0 34.3 39.2 18.4 116.7 64.6 45.0 40.1 45.0 28.9 53.5 46.0 48.2 41.6 35.4 37.6 213.9 34.5 45.2 43.3 57.6 54.8 32.9 42.7 32.2 41.1 24.8 74.0 190.0 34.7 48.8 36.8 52.2 20.7 43.2 35.0 30.2 127.4 37.5 43.1 51.5 170.9 201.9 37.8 34.1 44.8 63.2 63.0 39.2 33.1 48.3 109.1 26.3 47.8 41.4 86.1 81.9 52.8 70.3 99.9 51.1 51.1 36.6 67.1 BTBD1 ENSG00000064726 "BTB domain containing 1" Q9H0C5 15 83016423-83067252 "Predicted intracellular proteins" "Differentiation, Myogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 325.0;tongue: 230.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024263, HPA067671" Enhanced Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Cytoplasmic bodies" "Nucleoplasm, Cytosol" "HPA024263: , HPA067671: AB_2685882" "unprognostic (1.63e-1)" "unprognostic (4.61e-2)" "unprognostic (1.35e-1)" "unprognostic (5.54e-2)" "unprognostic (1.80e-1)" "unprognostic (3.17e-2)" "unprognostic (4.80e-2)" "unprognostic (1.65e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (1.07e-1)" "prognostic favorable (6.21e-7)" "unprognostic (8.94e-3)" "unprognostic (8.27e-2)" "unprognostic (7.71e-2)" "unprognostic (1.89e-2)" 36.8 26.7 39.8 24.9 41.0 36.3 28.8 40.4 48.1 24.8 26.2 33.4 32.5 24.2 25.7 30.4 31.5 28.7 107.2 41.3 43.8 37.8 34.3 23.9 36.7 40.7 41.4 23.6 17.2 46.4 22.1 24.1 38.5 30.1 35.5 28.4 21.0 24.0 325.0 16.5 29.9 26.5 44.4 25.9 23.9 58.4 46.8 35.5 37.1 230.8 34.2 36.2 18.2 46.0 45.8 43.1 37.3 37.0 57.5 98.2 19.5 64.9 88.0 54.8 60.6 27.4 46.4 91.0 78.4 73.2 45.6 56.4 82.7 52.0 64.4 73.4 67.1 77.7 62.6 39.6 67.6 74.2 82.9 80.6 45.8 37.2 55.4 71.0 82.0 35.2 70.2 49.9 117.2 24.1 55.8 38.5 52.2 39.9 47.0 57.1 94.4 45.5 55.0 106.7 64.9 46.6 75.1 61.6 111.2 50.7 46.5 61.6 82.9 61.9 46.1 86.0 91.2 50.6 84.0 88.4 66.7 123.6 43.8 1.3 2.9 5.7 3.1 3.2 2.7 2.7 2.9 4.0 5.2 3.4 3.2 3.2 1.6 2.4 4.2 2.2 3.0 1.3 39.8 41.0 40.4 48.1 41.3 43.8 40.7 41.4 38.5 44.4 46.8 46.0 24.2 16.0 5.8 30.7 22.0 15.2 13.7 9.6 13.6 9.4 11.4 6.9 84.9 8.6 18.1 11.0 6.2 8.4 23.6 20.8 17.6 14.2 35.8 19.9 16.6 16.8 23.3 18.7 36.0 10.5 13.5 15.8 18.8 14.5 17.7 11.0 17.2 11.0 18.0 11.8 38.4 10.8 14.2 23.6 24.6 24.5 8.7 21.2 12.4 37.5 22.8 11.1 9.2 32.2 28.6 15.1 19.8 11.3 22.6 11.8 15.8 15.7 24.7 8.6 6.6 21.0 15.3 46.2 14.9 16.0 12.1 8.1 18.8 22.0 18.4 18.7 BTBD18 ENSG00000233436 "BTB domain containing 18" B2RXH4 11 57743514-57751781 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 3.1;testis: 2.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.7;Cone photoreceptor cells: 4.2;Rod photoreceptor cells: 1.6;Spermatocytes: 5.5;Spermatogonia: 3.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049325 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Plasma membrane" Vesicles "HPA049325: AB_2680713" "unprognostic (6.68e-2)" "unprognostic (3.13e-2)" "unprognostic (3.43e-1)" "unprognostic (4.81e-2)" "unprognostic (1.75e-1)" "unprognostic (2.47e-2)" "unprognostic (8.69e-3)" "unprognostic (4.84e-3)" "unprognostic (1.77e-1)" "unprognostic (2.96e-1)" "unprognostic (7.17e-3)" "unprognostic (5.95e-3)" "unprognostic (1.42e-2)" "unprognostic (2.34e-2)" "unprognostic (3.15e-1)" "unprognostic (3.34e-1)" "unprognostic (2.88e-1)" 0.0 0.0 0.1 0.0 0.3 0.4 0.0 3.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.4 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.3 3.1 0.9 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.4 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 5.5 3.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 BTRC "beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1" ENSG00000166167 "Beta-transducin repeat containing E3 ubiquitin protein ligase" Q9Y297 10 101354033-101557321 "Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 109.7;Excitatory neurons: 154.0;Inhibitory neurons: 144.4;Oligodendrocyte precursor cells: 183.5;Oligodendrocytes: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031156, CAB032986" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "CAB032986: AB_2243598, HPA031156: AB_2673764" "unprognostic (1.43e-1)" "unprognostic (2.35e-2)" "unprognostic (8.88e-2)" "unprognostic (2.09e-1)" "unprognostic (3.55e-1)" "unprognostic (2.73e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.22e-1)" "unprognostic (1.59e-2)" "unprognostic (8.80e-3)" "unprognostic (5.05e-1)" "unprognostic (2.81e-3)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (2.23e-1)" 5.2 9.2 16.3 3.8 19.3 2.8 8.5 8.9 17.4 6.8 7.8 6.3 3.9 6.1 10.5 8.4 7.7 5.8 14.6 18.9 16.3 8.0 6.4 4.9 4.2 10.7 12.6 11.0 6.5 13.1 9.4 7.9 13.7 8.8 4.7 21.6 6.9 5.9 12.2 6.8 4.7 7.1 10.0 6.5 5.7 13.8 16.3 6.4 8.5 12.1 5.6 6.4 6.7 13.7 8.7 13.0 17.2 20.0 16.1 14.1 6.3 12.0 18.4 11.8 10.0 9.0 6.5 13.8 11.8 9.9 12.3 12.9 14.1 13.0 11.7 9.5 11.5 10.1 8.0 11.5 8.9 14.9 5.7 9.0 14.7 10.4 18.4 22.4 15.3 12.7 11.0 4.5 12.0 7.2 9.8 7.5 7.8 9.0 9.9 12.4 24.6 2.8 10.3 5.4 12.9 11.2 8.1 3.5 11.3 19.2 9.2 5.1 12.7 6.1 10.3 8.6 8.5 7.5 18.2 8.7 6.4 7.3 3.9 1.8 1.7 1.8 2.9 1.5 2.8 2.5 3.0 2.5 2.3 2.1 3.4 2.8 1.1 2.5 1.6 1.1 2.8 1.6 16.3 19.3 8.9 17.4 18.9 16.3 10.7 12.6 13.7 10.0 16.3 13.7 8.6 3.2 9.4 109.7 6.9 5.6 4.1 6.9 12.5 32.5 10.0 7.4 28.0 8.6 10.6 3.7 29.2 11.5 6.1 5.0 7.9 9.7 41.9 11.7 12.4 9.0 3.0 20.6 154.0 7.2 7.2 10.3 3.6 10.6 13.9 10.1 6.4 6.7 5.9 16.8 144.4 4.9 6.1 3.5 2.5 21.6 9.0 5.0 1.8 69.3 4.6 13.6 8.2 183.5 148.0 7.9 3.2 10.5 6.3 6.6 5.5 9.4 13.0 26.0 6.6 8.3 7.6 33.8 18.3 7.4 7.1 12.4 8.2 5.9 4.8 6.2 BUD31 "Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W" ENSG00000106245 "BUD31 homolog" P41223 7 99408641-99419616 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028943 Approved Approved Nucleoplasm,Microtubules,Centrosome NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Microtubules, Centrosome" "HPA028943: AB_10602396" "unprognostic (1.68e-1)" "unprognostic (2.73e-2)" "unprognostic (2.89e-2)" "unprognostic (2.63e-2)" "unprognostic (5.29e-2)" "unprognostic (2.38e-2)" "unprognostic (2.02e-3)" "unprognostic (2.16e-2)" "unprognostic (4.02e-2)" "unprognostic (1.46e-2)" "unprognostic (8.71e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (1.42e-1)" "unprognostic (4.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.71e-1)" 48.2 47.1 51.3 32.6 51.0 91.7 45.9 54.5 59.7 37.8 52.3 46.4 32.0 38.1 35.4 49.6 39.9 32.2 39.6 51.9 51.8 65.5 42.9 43.4 45.5 51.4 51.3 39.0 33.9 41.1 54.0 33.9 51.6 42.3 25.7 14.8 37.9 30.8 31.6 40.8 35.2 29.2 51.5 40.9 44.0 68.4 55.0 41.1 41.2 25.1 35.8 40.3 40.7 53.2 111.2 123.9 67.5 153.9 67.3 75.0 67.0 103.7 96.7 113.4 124.1 148.5 104.5 83.7 122.7 98.3 123.8 65.5 76.0 92.9 93.8 102.3 106.9 61.1 83.1 98.2 139.4 106.0 78.2 73.8 112.1 104.1 195.1 66.4 89.8 87.6 151.7 182.3 106.2 283.9 143.3 281.2 152.2 114.6 156.8 73.2 69.5 145.7 100.7 85.6 120.3 145.8 101.8 114.9 216.8 43.8 72.2 129.0 74.8 108.1 138.5 216.8 163.6 115.0 207.2 220.9 94.9 153.6 199.4 390.7 206.8 516.9 175.8 232.0 164.7 226.1 165.5 171.2 175.9 223.9 140.0 145.7 451.2 203.7 252.6 171.2 215.7 360.5 51.3 51.0 54.5 59.7 51.9 51.8 51.4 51.3 51.6 51.5 55.0 53.2 103.2 83.3 81.2 3.6 88.1 192.7 142.3 192.7 103.6 32.8 94.8 134.1 12.8 68.6 110.5 92.0 10.4 169.9 118.5 157.7 238.7 169.9 173.1 137.3 91.7 98.1 146.8 85.2 5.7 187.1 163.0 97.9 65.2 111.9 91.2 79.6 86.0 84.3 151.5 16.8 5.6 187.2 111.9 89.2 125.1 121.3 82.0 90.8 136.9 5.6 148.5 103.5 116.4 5.0 6.8 248.1 153.8 74.1 68.4 153.9 155.4 242.3 171.2 40.1 59.2 77.4 144.3 298.2 135.7 99.1 183.8 182.4 112.0 86.9 132.3 174.8 BYSL Enp1 ENSG00000112578 "Bystin like" Q13895 6 41921499-41933046 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031217, HPA031219" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA031217: AB_10599488, HPA031219: AB_10601989" "unprognostic (6.12e-3)" "unprognostic (6.97e-2)" "unprognostic (2.90e-1)" "unprognostic (2.33e-3)" "unprognostic (4.38e-2)" "unprognostic (2.73e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.09e-2)" "unprognostic (2.51e-1)" "unprognostic (6.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.15e-8)" "unprognostic (4.39e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-3)" "unprognostic (5.99e-2)" 10.7 10.1 6.0 8.2 6.1 7.4 8.8 5.7 6.2 6.4 5.8 6.8 4.7 8.2 5.4 9.2 8.5 5.4 7.2 6.1 6.7 6.5 10.7 5.1 8.4 6.0 6.7 8.1 11.6 6.5 3.6 10.0 6.9 6.8 7.0 2.5 4.8 6.5 20.1 8.0 4.0 11.9 5.9 5.8 5.5 7.9 6.6 12.2 5.2 10.8 13.2 15.4 5.9 6.2 50.6 52.1 30.2 54.2 21.8 25.5 59.7 44.0 21.6 66.7 48.9 72.1 15.7 78.2 43.9 32.9 51.9 34.3 91.6 61.0 58.0 30.1 89.2 72.7 37.3 81.5 38.6 58.8 36.0 30.1 39.5 67.2 62.1 16.9 50.5 47.3 96.1 26.0 48.7 70.8 74.2 68.3 29.0 162.4 50.9 77.9 38.2 57.3 45.2 37.9 65.6 37.4 30.0 37.8 58.2 26.3 38.0 58.6 39.3 49.0 53.5 31.4 77.2 24.6 33.0 185.8 14.5 57.9 49.9 0.0 3.8 0.7 4.3 3.9 5.9 3.8 2.5 3.5 6.0 5.5 1.6 3.3 0.5 6.1 3.0 9.2 3.3 2.3 6.0 6.1 5.7 6.2 6.1 6.7 6.0 6.7 6.9 5.9 6.6 6.2 6.4 0.0 3.9 0.7 6.7 31.0 34.5 19.2 8.6 2.8 8.6 8.5 2.8 5.7 9.5 1.8 4.2 22.1 4.8 4.6 3.9 21.4 10.4 7.9 12.1 10.9 5.4 6.3 2.8 17.5 24.4 11.4 4.6 9.8 2.5 11.4 3.9 6.8 12.0 0.0 2.5 6.5 12.2 1.0 7.3 6.8 8.1 5.1 8.8 1.9 6.6 4.4 9.2 4.0 2.8 23.5 2.9 7.2 4.9 26.2 2.2 10.5 5.1 3.4 6.6 16.1 13.8 10.8 25.7 14.0 25.3 29.1 4.1 18.2 11.4 32.2 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C10orf62 bA548K23.1 ENSG00000203942 "Chromosome 10 open reading frame 62" Q5T681 10 97589721-97590934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 155 "testis: 277.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 9848.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA072947 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Vesicles" "HPA072947: AB_2686562" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (2.81e-1)" "unprognostic (5.36e-2)" "unprognostic (3.62e-1)" "unprognostic (1.20e-1)" "unprognostic (3.63e-2)" "unprognostic (2.53e-2)" "unprognostic (2.04e-2)" 0.0 0.2 0.3 0.0 0.8 0.0 0.2 1.4 0.4 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.7 0.7 0.0 0.0 0.9 1.0 0.0 0.3 0.1 0.2 0.0 0.9 0.3 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.5 0.0 0.0 277.9 0.8 0.0 0.1 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.4 0.4 0.3 0.5 0.9 1.0 0.9 0.5 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1711.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9848.3 39.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.3 0.0 0.0 6.6 0.0 0.0 40.7 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C10orf90 "bA422P15.2, FATS, FLJ32938" ENSG00000154493 "Chromosome 10 open reading frame 90" Q96M02 10 126424997-126798708 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 819.4" "Cancer enriched" "Detected in some" 5 "melanoma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 118.8;U-2197: 36.1;U-266/84: 27.2;U-87 MG: 37.0;WM-115: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038648, HPA075229" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038648: AB_10672721, HPA075229: " "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (7.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.30e-2)" "unprognostic (1.98e-3)" "unprognostic (5.06e-2)" "unprognostic (9.34e-3)" "unprognostic (3.73e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (5.06e-11)" "unprognostic (2.69e-3)" "unprognostic (9.91e-3)" "unprognostic (1.26e-1)" "unprognostic (2.88e-1)" 0.7 0.0 30.4 0.1 74.4 0.0 4.7 41.9 47.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 29.9 37.4 0.3 0.1 0.0 0.0 60.4 53.8 0.1 0.2 0.0 0.3 0.3 57.0 0.0 0.1 0.0 10.6 0.0 0.1 1.1 0.1 0.0 29.8 0.0 0.0 6.5 68.0 1.1 0.3 0.4 0.7 0.0 0.0 112.1 0.3 0.1 0.0 0.0 0.8 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.3 0.0 1.6 0.0 0.9 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 2.6 0.0 0.0 0.0 0.0 118.8 0.0 0.0 0.2 0.0 4.7 0.0 36.1 0.7 0.0 27.2 0.0 37.0 0.0 29.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.4 74.4 41.9 47.7 29.9 37.4 60.4 53.8 57.0 29.8 68.0 112.1 0.2 0.0 0.0 24.5 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 120.5 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 142.7 0.3 0.0 0.0 3.7 0.0 0.0 0.0 181.0 819.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 1.3 0.5 0.0 0.0 4.2 0.1 0.0 0.0 0.0 C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 107.7;Proximal enterocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 222.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" 25.0 17.6 8.9 20.7 12.2 4.7 21.0 12.1 12.7 23.3 8.2 29.2 53.8 39.2 7.3 15.5 22.2 17.6 31.5 9.7 10.5 17.0 87.4 24.1 15.5 14.4 11.6 19.3 27.3 7.3 14.5 16.1 12.5 22.9 17.4 3.0 34.0 17.6 13.7 15.4 59.4 32.6 11.0 20.8 23.6 14.6 12.8 6.4 17.0 15.2 16.7 22.3 19.4 15.2 44.8 45.5 26.4 51.6 62.1 62.5 29.7 105.4 67.5 51.8 53.1 96.2 26.9 20.1 31.7 131.3 47.2 49.4 39.1 47.4 33.2 22.1 23.1 21.4 44.8 65.3 50.1 18.3 68.7 52.1 34.6 78.8 32.0 31.0 21.2 10.6 37.9 32.2 44.6 55.7 4.5 26.4 44.2 72.1 53.8 8.2 44.8 104.1 23.9 21.1 17.3 31.8 33.3 27.1 222.8 21.8 25.6 15.3 23.3 80.8 50.2 103.3 47.3 39.4 41.4 18.8 65.1 14.1 79.9 16.7 12.1 12.6 14.0 19.0 9.4 26.7 7.9 8.9 19.5 35.7 7.3 7.7 1.8 9.9 14.1 26.7 8.4 12.6 8.9 12.2 12.1 12.7 9.7 10.5 14.4 11.6 12.5 11.0 12.8 15.2 6.8 9.6 3.6 3.3 25.5 14.0 12.2 11.7 9.6 4.8 8.2 8.9 10.4 11.5 6.9 9.2 2.1 11.9 12.4 36.2 1.9 21.9 3.5 5.3 17.8 6.6 4.8 9.1 4.1 31.5 30.7 21.1 18.3 6.8 45.0 5.0 9.3 107.7 15.8 0.0 4.2 50.0 6.1 12.9 23.5 7.1 14.0 12.3 28.4 5.6 14.9 6.8 18.6 6.6 8.5 26.9 16.6 16.1 67.0 13.0 162.5 10.6 9.4 2.9 13.1 11.2 20.2 20.7 27.1 9.6 11.2 10.5 6.5 9.6 15.5 10.6 C11orf42 MGC34805 ENSG00000180878 "Chromosome 11 open reading frame 42" Q8N5U0 11 6205557-6211135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "testis: 25.4" "Cell type enriched" "Detected in some" 5 "Late spermatids: 818.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;HeLa: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063404 Enhanced Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nuclear membrane, Vesicles" "HPA063404: AB_2685006" "unprognostic (4.79e-2)" "unprognostic (1.83e-1)" "unprognostic (3.18e-1)" "unprognostic (2.56e-1)" "unprognostic (1.39e-3)" "unprognostic (3.49e-3)" "unprognostic (2.05e-1)" "unprognostic (5.39e-2)" "unprognostic (1.26e-1)" "unprognostic (3.50e-2)" "unprognostic (9.30e-2)" "unprognostic (6.47e-3)" "unprognostic (7.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (2.07e-2)" "unprognostic (4.74e-2)" 0.0 0.1 0.5 0.2 0.5 0.1 0.1 1.4 0.7 0.1 0.0 0.3 0.9 0.3 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.4 0.2 0.0 0.1 1.5 0.7 0.0 0.0 0.2 0.3 25.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.2 1.3 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.0 0.2 0.3 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.1 0.1 0.3 0.1 0.3 0.1 0.6 0.1 0.1 0.3 0.1 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.4 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 818.5 1.5 0.2 0.0 1.0 0.0 0.0 0.0 2.0 2.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C11orf68 "BLES03, P5326" ENSG00000175573 "Chromosome 11 open reading frame 68" Q9H3H3 11 65916810-65919062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045938 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA045938: AB_10961633" "unprognostic (3.18e-1)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (1.23e-1)" "unprognostic (9.25e-2)" "unprognostic (1.15e-2)" "unprognostic (9.88e-2)" "unprognostic (5.98e-2)" "unprognostic (9.88e-2)" "unprognostic (2.73e-1)" "unprognostic (1.50e-3)" "prognostic favorable (5.02e-6)" "unprognostic (2.16e-1)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (1.18e-1)" 36.0 29.3 68.1 14.9 70.3 10.1 33.5 74.7 82.3 50.4 59.4 50.1 17.2 56.1 39.0 29.7 40.5 20.7 50.7 71.0 65.1 31.2 28.0 31.9 24.8 69.0 67.0 43.4 27.2 25.6 24.0 23.4 67.6 42.6 15.7 12.5 30.9 31.7 81.1 32.8 31.0 27.0 66.3 41.6 32.8 53.9 67.9 29.1 32.6 51.4 21.3 45.9 39.5 71.4 76.4 33.6 20.4 22.2 70.0 67.3 17.6 59.7 90.2 74.3 45.2 12.6 83.9 15.6 40.6 89.5 118.6 24.0 15.9 36.6 39.8 24.2 16.1 18.5 23.4 33.2 55.7 14.9 23.7 62.9 53.8 53.9 58.9 76.6 56.1 26.1 25.1 37.7 136.2 34.5 19.7 35.9 20.5 16.5 165.8 28.8 23.1 44.4 39.6 14.5 13.9 21.6 23.1 30.1 59.8 21.0 39.0 14.0 61.4 118.0 57.9 162.1 30.9 25.3 11.9 13.1 69.8 11.1 94.1 6.8 2.5 3.7 5.3 3.9 3.8 3.0 3.4 4.4 2.0 5.3 5.2 5.2 9.1 3.8 2.1 2.7 4.2 2.2 68.1 70.3 74.7 82.3 71.0 65.1 69.0 67.0 67.6 66.3 67.9 71.4 17.8 16.0 5.1 6.5 7.3 15.3 32.9 4.2 6.8 11.4 14.7 22.5 16.6 14.3 2.3 16.5 10.4 16.4 14.5 10.8 7.9 14.5 7.9 8.1 17.8 13.8 4.8 2.1 7.9 11.7 16.5 18.5 7.1 11.8 3.8 12.9 18.2 10.5 14.2 16.8 7.5 13.1 4.1 13.9 7.5 24.5 21.5 8.7 10.6 7.5 14.1 26.7 22.6 4.5 8.6 19.3 3.4 35.3 3.6 23.2 11.8 5.4 1.9 9.9 19.7 13.5 16.4 15.0 17.1 6.2 12.8 21.9 8.3 23.3 9.2 31.3 C11orf96 AG2 ENSG00000187479 "Chromosome 11 open reading frame 96" Q7Z7L8 11 43925342-43943878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 750.2;ovary: 721.3" "Cell type enhanced" "Detected in many" "Adipocytes: 796.5;Endometrial stromal cells: 906.3;Fibroblasts: 801.3;Granulosa cells: 982.4;Peritubular cells: 474.3;Smooth muscle cells: 1942.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "SH-SY5Y: 197.7" "Low region specificity" "Detected in all" HPA038843 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" No NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Focal adhesion sites, Cytosol" "HPA038843: AB_10673296" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.28e-2)" "unprognostic (8.15e-3)" "unprognostic (5.49e-2)" "unprognostic (3.42e-3)" "unprognostic (8.11e-3)" "unprognostic (1.15e-2)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (2.34e-5)" "unprognostic (2.65e-2)" "unprognostic (2.07e-1)" "unprognostic (1.18e-2)" "unprognostic (3.19e-2)" 478.3 199.0 28.7 39.2 24.3 4.9 203.5 26.1 34.2 305.0 18.4 151.0 19.7 283.4 8.7 44.8 750.2 61.1 269.3 24.8 44.4 226.8 179.2 377.9 6.8 93.8 42.4 721.3 60.7 3.2 126.5 15.4 38.5 157.3 8.4 1.3 22.2 14.3 110.8 97.2 130.3 28.4 35.1 54.4 240.2 67.8 44.5 5.0 119.4 10.3 0.7 176.3 148.1 21.0 0.0 0.0 0.0 0.0 4.0 2.0 1.1 0.3 1.3 0.0 0.1 0.1 0.0 0.0 0.5 0.5 2.1 0.1 0.4 0.0 0.0 0.0 2.9 6.2 0.1 0.0 0.8 0.5 0.6 0.3 0.1 1.4 0.0 0.0 1.2 2.1 2.3 0.0 0.0 0.0 2.4 2.7 1.7 0.0 0.9 10.3 0.7 4.7 0.0 0.0 2.2 197.7 0.0 0.0 19.4 5.5 0.0 2.3 2.7 9.2 3.8 2.3 0.2 22.5 0.2 3.2 7.1 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 24.3 26.1 34.2 24.8 44.4 93.8 42.4 38.5 35.1 44.5 21.0 796.5 6.4 139.9 0.0 1.9 92.9 15.2 1.6 5.2 15.4 8.2 13.7 6.0 0.0 1.9 0.0 2.1 1.5 13.7 0.3 0.0 4.5 4.3 34.1 906.3 260.3 0.0 2.7 0.0 0.6 4.4 801.3 4.1 183.3 13.9 982.4 172.7 6.4 3.8 1.7 0.0 0.2 0.0 8.4 171.8 13.9 215.6 27.1 174.3 0.0 0.1 2.7 0.0 0.0 0.0 1.9 0.0 474.3 9.4 73.6 0.0 0.0 0.9 9.3 302.4 173.2 1942.9 2.1 1.5 6.5 88.5 3.1 14.2 243.9 0.1 50.5 C12orf65 "FLJ38663, SPG55" ENSG00000130921 "Chromosome 12 open reading frame 65" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (9.07e-3)" "unprognostic (1.51e-2)" "unprognostic (5.30e-2)" "unprognostic (8.19e-3)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (4.29e-9)" "unprognostic (9.33e-3)" "unprognostic (2.39e-1)" "unprognostic (2.50e-2)" "unprognostic (6.33e-3)" "unprognostic (1.20e-2)" "unprognostic (2.01e-2)" "unprognostic (3.89e-2)" "unprognostic (3.19e-2)" "unprognostic (9.83e-3)" "prognostic favorable (7.82e-5)" 7.3 12.6 16.2 10.2 16.1 9.0 8.0 23.0 19.6 13.0 13.5 10.9 11.4 12.1 13.8 9.5 11.4 8.2 15.0 16.0 13.2 12.6 14.5 8.9 18.2 12.6 12.3 17.2 8.5 10.2 19.7 7.3 14.9 13.7 8.2 15.7 16.2 9.0 13.0 13.8 11.3 7.0 8.8 12.8 10.6 16.7 14.8 60.0 12.3 12.5 13.4 10.3 11.0 18.3 28.4 20.5 20.8 39.1 12.0 11.1 13.7 22.3 16.5 25.1 18.0 21.8 15.8 36.1 20.3 8.4 23.5 20.4 25.7 12.5 25.0 29.2 22.5 44.0 20.7 18.6 26.1 20.4 19.7 14.2 33.2 18.9 35.1 37.0 17.0 53.6 45.6 13.4 16.7 12.3 46.2 39.3 13.7 25.6 31.7 35.7 25.9 33.5 22.8 13.0 40.7 18.2 24.0 8.8 23.4 16.5 18.3 24.7 14.8 23.1 27.3 23.3 24.4 22.7 28.3 32.6 17.1 26.2 28.1 85.3 12.9 50.6 53.9 14.9 67.6 83.9 72.3 71.9 21.7 73.5 96.6 78.2 11.8 63.3 16.3 36.6 73.1 33.5 16.2 16.1 23.0 19.6 16.0 13.2 12.6 12.3 14.9 8.8 14.8 18.3 46.0 41.7 47.7 9.8 54.3 45.4 36.7 29.4 59.2 34.5 23.3 50.0 52.7 14.3 18.0 25.8 14.6 41.1 56.2 16.4 60.7 20.7 22.9 12.2 24.2 27.9 9.6 37.0 13.7 10.8 22.8 41.3 23.0 11.2 15.2 24.1 18.5 33.5 14.3 45.4 15.9 20.7 28.5 9.2 24.2 6.2 37.9 19.7 24.9 7.5 26.3 35.7 44.3 14.6 10.4 13.6 17.4 42.2 42.2 22.8 19.9 39.3 14.8 36.6 13.1 42.7 33.1 115.2 59.7 40.6 36.1 10.8 63.0 43.3 20.8 8.0 C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.5" "Cell type enhanced" "Detected in many" "Early spermatids: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: AB_10794735" "unprognostic (9.24e-2)" "unprognostic (3.26e-3)" "unprognostic (3.66e-3)" "unprognostic (7.20e-2)" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.98e-4)" "unprognostic (8.96e-2)" "unprognostic (1.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.03e-3)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (6.27e-2)" "prognostic favorable (1.61e-4)" 6.0 11.4 15.6 7.7 15.4 4.4 7.9 17.1 16.1 8.5 13.3 7.2 7.0 8.2 10.3 6.4 7.3 4.6 12.3 15.5 16.7 10.3 8.3 5.8 9.2 14.7 15.0 10.1 7.7 10.0 10.8 6.1 15.2 8.7 7.6 13.2 7.2 7.3 42.5 8.3 6.8 6.5 14.4 6.9 8.9 10.9 15.3 8.3 12.9 27.6 8.9 7.3 6.9 17.3 11.8 21.2 31.8 19.4 8.9 11.6 20.7 12.6 7.4 13.4 10.8 23.2 9.9 13.7 15.9 7.5 11.7 18.3 19.1 15.6 10.1 19.7 38.4 20.9 32.9 29.1 13.1 30.8 18.2 10.3 17.6 6.9 11.9 32.5 12.5 39.5 27.0 9.2 12.5 13.2 34.5 46.1 15.6 11.0 35.9 19.7 11.9 13.7 17.8 16.6 51.8 18.5 13.0 21.9 29.7 14.1 36.4 16.7 6.5 16.4 9.3 12.4 12.8 24.5 40.6 28.8 22.4 17.4 14.5 10.1 5.6 10.6 11.7 5.0 11.4 14.6 10.6 11.1 8.6 11.3 15.7 14.8 1.7 14.5 4.5 13.3 17.0 4.2 15.6 15.4 17.1 16.1 15.5 16.7 14.7 15.0 15.2 14.4 15.3 17.3 6.8 6.4 6.8 7.5 7.8 6.0 9.4 16.3 18.8 16.3 9.0 11.0 16.5 7.2 10.0 9.2 0.0 11.6 8.6 7.1 27.4 20.3 87.1 8.7 10.3 8.3 11.4 18.5 5.0 12.1 11.7 7.9 15.3 9.1 9.5 13.8 8.9 15.5 17.5 8.4 6.0 13.2 20.3 7.9 5.1 36.6 8.7 8.7 1.8 2.8 12.4 17.1 22.6 7.5 9.0 19.9 5.6 8.6 13.7 13.7 16.0 25.9 10.9 15.2 6.6 5.6 11.7 31.1 25.6 16.0 5.3 8.9 8.8 6.4 12.3 8.6 C15orf61 LOC145853 ENSG00000189227 "Chromosome 15 open reading frame 61" A6NNL5 15 67521131-67530146 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 23.7" "Cell type enhanced" "Detected in all" "Early spermatids: 222.6;Spermatocytes: 258.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062820 Approved Nucleoli,Vesicles,Cytosol "Secreted - unknown location" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Vesicles" Cytosol "HPA062820: AB_2684874" "unprognostic (1.35e-1)" "unprognostic (9.42e-3)" "unprognostic (2.11e-1)" "unprognostic (5.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.87e-3)" "unprognostic (8.95e-2)" "unprognostic (4.01e-2)" "unprognostic (1.04e-2)" "unprognostic (8.45e-2)" "prognostic favorable (5.31e-5)" "unprognostic (2.42e-2)" "unprognostic (9.78e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" 4.7 3.8 2.3 1.5 6.2 5.3 3.6 7.1 4.2 3.1 0.0 2.3 2.8 2.3 1.9 2.0 2.9 1.5 5.7 3.8 1.6 3.0 2.5 2.3 1.3 1.0 2.4 2.7 4.2 4.4 5.1 2.0 1.0 2.5 2.2 10.8 2.6 2.1 23.7 4.1 1.8 1.4 0.7 1.7 2.4 7.7 2.1 1.4 2.8 8.3 1.0 2.2 2.4 2.3 4.2 4.4 1.1 4.9 5.0 7.2 3.1 1.8 3.2 3.3 2.6 3.4 2.9 3.5 3.8 2.0 3.9 4.9 4.4 1.2 2.7 2.1 10.4 3.7 3.3 4.6 3.2 4.6 3.0 7.5 3.4 1.1 4.0 2.4 1.6 10.6 4.3 7.6 1.0 2.4 3.8 7.6 1.8 3.3 5.6 5.1 2.5 13.0 2.3 2.9 6.4 4.8 3.2 3.0 6.1 2.1 2.7 7.1 1.6 4.4 6.8 5.5 4.7 7.1 11.2 8.5 1.9 9.0 2.2 7.9 4.3 7.8 4.5 3.7 5.2 5.3 5.9 4.5 4.8 3.6 6.2 5.0 0.5 3.8 3.2 4.9 4.0 3.5 2.3 6.2 7.1 4.2 3.8 1.6 1.0 2.4 1.0 0.7 2.1 2.3 28.0 22.4 13.5 4.9 23.1 67.2 32.6 32.3 120.7 75.5 55.7 82.3 74.5 18.6 14.3 16.5 37.5 42.6 23.8 38.6 80.3 25.1 222.6 17.5 24.2 26.8 27.1 11.8 14.8 29.8 31.9 56.8 15.8 17.1 34.8 15.2 22.9 44.7 30.5 13.5 15.7 47.5 48.8 24.8 25.6 42.6 41.0 19.9 37.4 3.7 15.6 97.1 23.7 5.0 8.5 27.6 48.4 25.6 37.4 63.3 49.0 77.1 8.4 93.9 32.9 38.2 38.7 258.9 52.1 62.7 60.9 20.5 34.4 28.9 39.2 20.0 C16orf70 "C16orf6, FLJ12076, lin-10, LIN10" ENSG00000125149 "Chromosome 16 open reading frame 70" Q9BSU1 16 67109941-67148544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 47.9;Oligodendrocytes: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041131, HPA041214" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA041131: AB_10795487, HPA041214: AB_10794267" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (3.74e-3)" "unprognostic (1.81e-2)" "unprognostic (6.29e-2)" "unprognostic (1.07e-1)" "unprognostic (4.38e-2)" "unprognostic (1.68e-1)" "unprognostic (2.15e-2)" 11.3 10.0 15.6 7.6 16.6 18.1 11.1 15.5 17.4 13.2 10.8 10.2 7.3 11.2 8.9 17.8 10.6 7.5 10.3 18.5 13.6 14.0 57.3 9.8 9.2 15.7 16.1 11.1 8.3 16.1 10.9 11.8 17.0 14.4 10.1 8.1 12.0 8.5 29.7 30.4 10.0 10.8 16.2 14.7 8.6 13.8 15.6 9.2 9.0 15.3 11.7 10.5 14.6 21.4 13.7 19.3 19.0 19.9 23.6 13.9 44.5 15.4 16.6 30.7 33.3 22.1 11.7 13.9 13.3 18.2 16.9 18.0 23.7 14.9 39.7 7.1 19.7 10.6 12.2 47.4 14.5 10.9 58.0 14.1 20.6 30.2 13.9 16.6 17.3 17.5 17.5 5.8 19.4 13.6 21.2 16.6 21.5 18.4 29.4 29.5 32.2 21.9 13.4 8.2 24.5 13.2 46.2 10.7 12.0 18.7 22.0 9.0 13.4 21.5 18.4 15.5 13.5 8.8 17.3 41.3 19.4 10.9 17.5 3.2 17.4 6.1 4.4 12.2 5.9 6.9 6.6 8.1 14.6 4.5 6.8 6.3 6.2 5.9 13.6 4.8 7.2 8.9 15.6 16.6 15.5 17.4 18.5 13.6 15.7 16.1 17.0 16.2 15.6 21.4 5.1 6.4 5.9 11.1 6.6 9.1 2.5 5.1 19.4 7.4 8.7 6.7 1.3 1.5 3.2 0.0 0.0 8.8 5.0 4.9 5.9 4.4 1.6 12.9 8.5 6.2 7.2 11.1 20.4 2.9 9.5 5.1 8.6 30.6 9.5 8.7 5.0 47.9 18.6 10.1 18.5 8.4 4.1 13.5 7.8 1.6 4.7 13.2 10.6 17.8 13.3 2.7 3.1 11.1 41.6 4.8 8.6 6.4 7.5 4.6 5.4 10.3 11.0 5.9 13.1 5.3 6.4 24.7 24.8 20.5 12.1 7.0 6.7 8.2 5.7 1.3 C17orf100 LOC388327 ENSG00000256806 "Chromosome 17 open reading frame 100" A8MU93 17 6651762-6693202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 32.9;Late spermatids: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 10.0;SH-SY5Y: 9.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA046824 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA046824: AB_2679825" "unprognostic (9.24e-3)" "unprognostic (1.79e-1)" "unprognostic (3.16e-1)" "unprognostic (6.37e-3)" "unprognostic (1.56e-1)" "unprognostic (1.90e-2)" "unprognostic (1.19e-1)" "unprognostic (8.99e-2)" "unprognostic (2.69e-1)" "unprognostic (2.02e-3)" "unprognostic (2.58e-3)" "unprognostic (4.72e-2)" "unprognostic (5.54e-3)" "unprognostic (4.52e-2)" "unprognostic (9.68e-2)" "unprognostic (9.44e-2)" "unprognostic (7.65e-2)" 0.9 1.6 4.1 1.7 4.9 0.5 1.5 3.3 4.8 1.9 2.2 1.6 3.0 1.6 2.2 4.3 2.0 1.1 0.6 3.5 4.5 2.4 3.6 1.2 3.2 3.2 3.7 1.3 4.5 3.5 9.5 0.8 3.2 2.5 1.5 5.3 2.8 1.0 0.6 7.3 3.0 0.8 3.4 2.9 2.4 5.5 4.1 1.7 3.3 0.8 1.2 1.9 2.3 3.9 1.1 2.1 4.6 1.5 0.7 1.3 2.2 0.6 3.4 1.4 2.7 3.2 1.5 1.3 2.3 1.1 3.6 4.1 0.9 2.2 2.0 5.6 6.3 1.2 2.4 10.0 1.6 0.2 3.2 1.8 2.1 0.7 1.5 4.1 0.8 6.7 1.6 1.2 1.8 2.4 1.4 2.1 0.6 1.9 1.4 2.6 0.8 2.0 2.9 1.0 4.8 9.4 2.9 0.3 3.4 1.4 2.5 0.3 1.3 1.3 2.6 0.8 1.1 1.7 1.2 0.8 1.1 0.4 3.1 3.9 0.9 4.0 1.2 1.3 1.6 2.3 2.2 1.4 1.6 2.5 2.5 1.4 0.8 1.4 1.3 0.5 1.5 0.9 4.1 4.9 3.3 4.8 3.5 4.5 3.2 3.7 3.2 3.4 4.1 3.9 1.7 0.0 1.7 0.0 3.2 2.8 5.4 4.8 8.0 3.8 4.9 5.0 0.4 0.0 4.9 0.0 2.1 1.7 0.6 3.8 1.9 4.1 32.9 3.0 3.0 1.8 7.7 1.3 1.4 3.2 1.8 1.6 4.1 2.9 8.9 4.7 0.0 0.0 1.2 1.7 1.4 7.1 10.2 0.0 1.3 48.7 0.9 0.7 1.8 1.0 1.2 5.1 1.0 1.5 2.2 3.3 2.6 1.9 0.9 4.5 9.0 2.1 2.4 5.8 6.6 1.9 3.0 16.4 4.6 7.0 3.0 1.5 1.7 3.8 3.9 5.1 C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 515.3;skin 1: 331.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2060.3;Pancreatic endocrine cells: 2590.4;Paneth cells: 1697.3;Proximal enterocytes: 1756.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.2" "Cell line enhanced" "Detected in many" "A-431: 745.5;A549: 1228.0;CAPAN-2: 767.1;HBEC3-KT: 744.6;hTCEpi: 799.2;OE19: 678.3;PC-3: 659.8" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: AB_2682478, HPA059696: AB_2684105" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-2)" "unprognostic (3.92e-3)" "unprognostic (2.37e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.63e-2)" "unprognostic (6.01e-2)" 43.1 5.0 2.8 17.6 3.1 3.6 25.5 2.9 4.4 82.4 2.9 187.5 186.7 6.1 0.6 515.3 91.5 49.5 32.9 2.3 2.6 28.2 1.3 91.3 0.9 3.1 3.0 4.6 8.9 0.5 12.7 7.9 3.4 26.2 104.1 0.1 123.3 18.3 3.9 331.1 189.5 4.0 2.5 10.7 151.5 1.5 3.8 4.1 18.9 4.3 30.8 102.2 224.3 2.5 745.5 1228.0 0.0 0.6 0.0 0.0 1.2 1.0 0.0 0.0 0.0 77.1 767.1 0.0 394.2 0.0 0.7 300.1 0.0 744.6 0.0 0.4 0.5 0.4 244.2 20.0 5.4 0.0 0.2 0.0 799.2 0.3 493.3 3.3 10.2 0.9 0.4 0.5 0.8 220.4 0.1 1.9 0.4 678.3 659.8 0.2 0.2 2.8 469.5 255.2 0.8 0.8 416.6 340.8 0.8 1.6 103.7 2.3 141.6 0.5 201.9 0.7 2.8 0.7 2.4 3.7 0.1 0.2 0.2 2.1 0.6 2.2 0.2 0.0 0.4 0.1 0.5 0.1 22.2 1.4 0.7 0.3 1.0 0.4 0.1 1.8 0.0 18.2 2.8 3.1 2.9 4.4 2.3 2.6 3.1 3.0 3.4 2.5 3.8 2.5 29.1 535.2 172.9 0.0 5.4 225.3 28.4 508.7 436.5 0.0 32.5 25.5 2.4 267.4 418.0 55.2 0.0 8.6 1.7 2060.3 1.9 207.7 0.7 144.3 26.0 18.4 76.1 3.6 0.1 753.8 1.3 44.7 353.7 273.2 38.2 3.7 3.6 0.4 1.3 0.0 0.0 842.0 99.7 1.4 15.1 5.1 4.1 32.9 1.8 0.0 4.9 0.0 0.0 0.0 0.0 2590.4 1697.3 0.0 5.7 35.7 1756.4 51.7 212.5 0.0 0.0 0.4 14.3 1.8 1.9 629.0 348.4 3.1 7.9 0.0 691.9 188.4 C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 98.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 90.1;Langerhans cells: 33.4;Macrophages: 59.2;monocytes: 86.7;Plasma cells: 24.7;Spermatocytes: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.3;eosinophil: 169.4;intermediate monocyte: 312.5;myeloid DC: 162.2;neutrophil: 230.1;non-classical monocyte: 392.8" "Group enriched" "Detected in all" 20 "dendritic cells: 162.2;granulocytes: 230.1;monocytes: 392.8" "Cell line enriched" "Detected in some" 4 "U-937: 50.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: AB_10603448, HPA055027: " "unprognostic (6.65e-3)" "prognostic favorable (2.43e-4)" "unprognostic (6.44e-4)" "unprognostic (6.98e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-3)" "unprognostic (3.56e-1)" "unprognostic (8.27e-2)" "unprognostic (5.60e-2)" "unprognostic (6.02e-2)" "unprognostic (9.74e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.75e-7)" "unprognostic (2.31e-1)" "unprognostic (4.00e-2)" "unprognostic (1.03e-2)" "unprognostic (2.11e-2)" 3.6 1.0 3.5 11.2 3.9 98.0 1.2 4.2 4.5 2.1 3.5 1.8 1.7 1.0 2.7 1.0 2.3 2.9 0.9 3.4 4.1 1.2 3.2 6.1 5.2 5.2 4.3 2.0 1.7 0.4 0.8 1.8 5.2 1.3 1.2 0.7 0.9 0.9 2.7 0.5 2.3 3.4 4.6 21.7 1.6 11.1 4.0 3.2 0.5 1.5 3.0 4.6 1.6 6.0 2.4 0.1 0.2 0.4 2.2 1.2 0.2 0.4 0.1 0.4 0.9 0.2 0.4 5.9 0.5 0.0 0.2 0.2 0.3 0.3 0.3 2.7 0.6 0.3 0.0 0.0 1.6 3.9 0.6 6.0 0.7 1.0 0.3 0.1 0.1 0.6 0.3 12.2 0.2 2.2 0.2 9.3 0.5 0.4 0.4 4.5 0.0 3.1 0.0 0.2 0.3 0.1 1.2 0.0 0.9 0.1 0.2 8.7 0.0 0.1 0.0 1.1 0.1 7.3 3.7 1.7 0.0 50.9 0.0 7.8 282.3 169.4 0.6 312.5 1.6 13.0 0.8 0.8 162.2 8.5 4.9 1.5 230.1 8.0 392.8 3.6 2.3 157.7 3.5 3.9 4.2 4.5 3.4 4.1 5.2 4.3 5.2 4.6 4.0 6.0 0.3 0.0 1.8 1.6 10.6 0.8 0.4 2.1 1.2 0.1 0.6 0.5 1.1 0.0 1.7 1.8 2.1 1.0 0.7 0.3 0.0 0.1 3.7 0.9 0.3 1.1 0.0 4.8 0.9 1.3 0.9 1.6 4.1 1.0 2.5 0.3 0.4 1.1 22.3 0.0 0.9 0.6 2.0 90.1 33.4 6.1 0.9 59.2 1.8 0.0 86.7 3.1 4.1 0.0 3.1 0.1 3.5 0.7 24.7 0.3 0.2 0.7 5.1 1.1 6.6 0.5 0.6 28.5 19.2 0.3 0.9 0.7 2.1 0.1 0.6 0.6 C19orf67 ENSG00000188032 "Chromosome 19 open reading frame 67" A6NJJ6 19 14081624-14085875 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 27 "testis: 6.6" "Group enriched" "Detected in some" 28 "Early spermatids: 30.0;Late spermatids: 28.2;Spermatocytes: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046351 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Nucleoli" "HPA046351: " "unprognostic (1.21e-1)" "unprognostic (6.84e-2)" "unprognostic (1.40e-1)" "unprognostic (6.45e-4)" "unprognostic (1.25e-1)" "unprognostic (6.81e-2)" "unprognostic (1.41e-1)" "unprognostic (4.76e-3)" "unprognostic (9.22e-2)" "unprognostic (1.65e-3)" "unprognostic (4.20e-3)" "unprognostic (3.74e-1)" "unprognostic (1.63e-2)" "unprognostic (3.25e-1)" "unprognostic (1.36e-1)" "unprognostic (1.51e-2)" "unprognostic (1.94e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.5 30.0 0.4 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 28.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.1 9.9 0.5 0.0 0.0 0.4 0.0 0.0 0.2 0.2 C19orf71 LOC100128569 ENSG00000183397 "Chromosome 19 open reading frame 71" A6NCJ1 19 3539154-3544030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 53.7" "Group enriched" "Detected in some" 69 "Early spermatids: 566.4;Late spermatids: 357.0" "Cancer enriched" "Detected in all" 5 "melanoma: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HeLa: 92.7;SK-MEL-30: 48.2;WM-115: 170.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA048654 Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Endoplasmic reticulum" "HPA048654: AB_2680480" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "unprognostic (7.04e-3)" "unprognostic (7.37e-2)" "unprognostic (4.74e-2)" "prognostic favorable (2.35e-4)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (7.23e-2)" "unprognostic (3.13e-2)" "prognostic favorable (2.03e-5)" "unprognostic (6.19e-2)" "prognostic favorable (2.02e-5)" "unprognostic (5.52e-3)" "unprognostic (1.02e-1)" "unprognostic (3.84e-2)" "unprognostic (1.97e-3)" 2.6 4.5 3.7 8.1 3.5 10.5 2.2 15.0 5.6 3.4 0.0 2.7 8.5 4.9 0.8 3.5 4.5 3.8 2.5 4.4 5.6 6.3 3.5 4.4 9.5 4.6 3.1 4.7 7.6 0.7 7.5 3.2 3.8 4.1 0.6 3.3 12.3 2.3 2.5 13.0 7.3 0.9 1.4 9.8 6.0 53.7 4.6 1.9 11.0 0.5 1.2 2.6 2.5 10.9 15.9 12.8 4.1 5.5 0.1 0.1 8.3 9.8 0.0 0.0 0.0 8.1 4.7 2.8 7.2 0.1 20.8 13.8 0.1 0.7 0.0 16.0 7.5 2.1 92.7 2.4 0.0 2.1 9.7 0.1 0.2 0.3 0.1 4.5 0.1 7.3 11.1 13.9 0.0 11.1 3.5 5.2 3.5 0.5 3.9 5.3 6.1 14.9 0.0 6.2 9.7 8.9 17.0 8.5 48.2 1.9 9.6 5.2 13.2 7.6 9.9 23.2 9.3 11.0 3.1 4.1 22.7 9.4 170.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.5 15.0 5.6 4.4 5.6 4.6 3.1 3.8 1.4 4.6 10.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 566.4 0.3 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 357.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 3.8 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 2.7 1.6 0.0 0.0 0.1 0.1 0.2 0.0 0.1 C1orf100 ENSG00000173728 "Chromosome 1 open reading frame 100" Q5SVJ3 1 244352635-244389663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 35.0" "Group enriched" "Detected in some" 151 "Early spermatids: 1207.7;Late spermatids: 851.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "K-562: 5.9" "Not detected" "Not detected" "HPA031179, HPA031180" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA031179: AB_10599995, HPA031180: AB_10599026" "unprognostic (9.84e-2)" "unprognostic (2.14e-3)" "unprognostic (3.37e-2)" "unprognostic (9.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.49e-2)" "unprognostic (5.45e-3)" "unprognostic (2.17e-2)" "unprognostic (4.00e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-5)" "unprognostic (1.85e-2)" "unprognostic (2.08e-3)" "unprognostic (2.53e-2)" "unprognostic (1.79e-1)" "unprognostic (2.85e-1)" "unprognostic (1.27e-4)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1207.7 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 851.9 5.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf109 FLJ20508 ENSG00000116922 "Chromosome 1 open reading frame 109" Q9NX04 1 37681570-37692249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.2;Suprabasal keratinocytes: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027110, HPA027127" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Nucleoli" "HPA027110: AB_10611813, HPA027127: AB_1845628" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (2.43e-1)" "unprognostic (3.30e-3)" "unprognostic (1.71e-2)" "unprognostic (7.13e-3)" "prognostic unfavorable (1.76e-7)" "unprognostic (1.93e-1)" "unprognostic (1.48e-2)" "unprognostic (8.38e-2)" "unprognostic (1.73e-1)" "unprognostic (3.79e-3)" "unprognostic (9.96e-2)" "unprognostic (1.66e-2)" "unprognostic (2.25e-1)" "unprognostic (7.96e-3)" "unprognostic (1.69e-1)" 8.8 10.7 7.7 7.3 6.8 8.0 9.7 7.1 7.5 8.9 5.9 7.2 8.2 10.2 10.0 10.1 9.8 6.9 8.3 7.0 7.5 9.2 7.8 5.5 11.9 7.0 8.1 13.4 14.6 15.0 6.1 10.4 7.6 10.6 5.6 5.3 12.3 10.1 9.7 10.5 5.7 8.2 7.9 7.7 6.9 8.3 10.3 9.1 11.4 10.0 9.7 8.1 7.9 8.2 17.7 20.1 16.9 27.8 14.5 10.4 38.5 20.9 14.7 30.7 22.6 30.8 20.8 25.0 24.4 9.2 14.2 25.3 31.5 21.2 31.3 40.3 35.1 28.3 20.7 19.5 27.9 31.6 18.0 14.2 25.7 30.4 39.8 13.4 15.7 21.6 57.2 29.5 17.7 12.1 30.9 13.9 52.9 18.1 38.0 30.2 35.4 69.0 16.4 14.9 50.8 24.4 18.4 27.9 43.1 16.9 15.7 13.9 10.6 30.7 19.3 25.0 40.8 24.0 29.0 52.0 15.4 30.4 33.0 3.5 9.7 6.9 18.9 7.9 29.9 21.2 22.8 18.3 11.6 18.7 28.8 25.0 1.9 24.8 8.8 54.1 12.5 15.0 7.7 6.8 7.1 7.5 7.0 7.5 7.0 8.1 7.6 7.9 10.3 8.2 10.9 6.4 7.9 4.2 12.9 50.2 24.1 5.9 22.8 10.1 15.6 15.1 5.5 5.7 10.8 3.7 10.4 14.9 12.2 6.7 13.7 10.5 1.5 5.8 12.8 11.5 4.2 45.3 9.5 7.3 14.0 14.4 6.1 6.2 11.4 9.6 6.4 6.6 5.4 16.8 7.2 5.1 8.2 4.4 9.0 1.0 9.9 4.8 12.4 4.7 7.3 10.4 17.5 5.0 5.0 10.2 8.1 13.9 10.9 21.3 5.5 8.9 5.6 14.6 0.0 17.5 8.5 25.7 25.5 15.5 62.1 7.9 12.0 11.9 8.3 13.2 C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9;Late spermatids: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: AB_1078885, HPA075399: " "unprognostic (2.79e-1)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-3)" "prognostic unfavorable (9.58e-6)" "unprognostic (1.34e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" "unprognostic (9.29e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (1.77e-6)" "unprognostic (4.10e-2)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.62e-4)" 4.0 4.8 9.6 1.6 8.0 2.4 3.8 0.9 10.4 5.3 3.2 6.1 1.8 4.2 1.1 8.6 4.8 2.2 4.3 9.4 1.0 7.7 6.7 3.9 1.8 6.3 2.7 4.3 3.7 0.7 5.3 1.4 2.8 6.9 0.6 1.6 4.6 2.3 2.2 5.0 4.1 0.5 0.7 5.5 6.0 22.9 5.4 1.8 4.5 0.3 0.9 5.5 5.9 6.9 15.7 12.0 5.6 10.0 1.5 1.6 13.3 9.0 2.1 7.8 5.1 6.5 14.7 4.3 10.8 2.8 6.4 12.2 2.5 7.1 2.2 8.6 18.2 3.1 19.6 7.0 3.6 5.5 7.3 3.2 2.8 3.3 1.6 2.3 3.8 6.4 18.6 3.1 2.8 11.9 10.2 13.2 4.7 5.9 19.7 12.0 6.7 8.5 4.7 4.7 11.8 16.1 6.8 12.2 7.6 1.6 7.8 6.5 5.2 8.3 8.8 11.9 9.2 5.6 8.3 7.8 6.8 14.9 6.5 8.1 2.6 1.4 2.6 2.6 2.8 2.5 2.5 3.0 1.7 2.2 2.5 2.6 0.5 2.7 1.8 2.2 0.9 2.3 9.6 8.0 0.9 10.4 9.4 1.0 6.3 2.7 2.8 0.7 5.4 6.9 6.3 0.0 7.7 20.2 3.4 7.5 3.6 6.2 4.6 5.9 8.9 6.6 2.3 5.7 7.1 9.2 4.2 5.0 4.9 13.6 1.9 8.2 60.9 8.6 8.2 4.4 4.2 5.2 26.5 7.0 14.0 4.2 20.4 9.0 5.7 9.0 3.3 5.3 3.9 13.5 21.8 7.4 6.1 1.0 4.8 124.1 2.8 3.9 3.6 2.8 6.0 3.2 9.2 10.6 24.5 7.8 3.5 1.5 6.9 5.1 3.4 1.8 10.4 8.2 0.0 3.5 4.8 18.3 6.8 4.2 7.0 4.9 4.6 4.4 9.4 4.9 C1orf189 ENSG00000163263 "Chromosome 1 open reading frame 189" Q5VU69 1 154199085-154206333 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "fallopian tube: 30.5;testis: 19.7" "Cell type enhanced" "Detected in some" "Early spermatids: 88.7;Endometrial ciliated cells: 30.7;Late spermatids: 19.6;Respiratory ciliated cells: 25.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045779 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Golgi apparatus, Plasma membrane" "HPA045779: AB_2679448" "unprognostic (8.23e-3)" "unprognostic (5.55e-3)" "unprognostic (2.39e-2)" "unprognostic (2.01e-3)" "unprognostic (2.50e-3)" "unprognostic (2.02e-1)" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.24e-2)" "unprognostic (8.78e-3)" "unprognostic (1.36e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (3.75e-2)" "unprognostic (2.06e-1)" "unprognostic (9.79e-2)" "unprognostic (3.05e-2)" 0.1 0.0 0.2 0.1 0.3 0.5 0.1 0.4 0.4 1.6 0.6 0.0 0.0 0.5 0.3 0.1 30.5 0.0 0.1 0.3 0.4 0.1 0.3 1.8 0.1 1.6 3.4 0.1 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.0 0.9 0.0 0.1 19.7 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.4 0.2 0.3 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.4 0.2 0.4 0.3 0.2 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.5 0.1 0.1 0.5 0.2 0.5 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.3 0.0 0.4 0.2 0.2 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.4 0.4 0.3 0.4 1.6 3.4 1.2 0.9 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.7 30.7 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.2 25.1 0.0 0.0 0.0 0.0 7.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C1orf35 "MGC4174, MMTAG2" ENSG00000143793 "Chromosome 1 open reading frame 35" Q9BU76 1 228100726-228105411 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046175 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Plasma membrane" Cytosol "HPA046175: AB_10959459" "unprognostic (1.12e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.71e-4)" "unprognostic (6.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.64e-2)" "unprognostic (5.44e-3)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "prognostic favorable (7.38e-4)" "unprognostic (6.12e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.70e-1)" "unprognostic (8.58e-2)" "unprognostic (5.56e-2)" "unprognostic (3.70e-2)" 11.3 12.5 20.6 6.3 20.4 14.3 11.7 19.5 24.4 15.5 18.2 13.4 7.9 13.4 5.5 18.8 13.0 4.0 9.4 20.5 20.3 11.2 11.6 8.6 9.0 20.8 19.7 16.1 12.9 7.4 9.9 7.1 20.6 14.2 3.9 2.7 12.5 8.5 9.6 19.6 10.5 5.0 19.2 10.8 12.3 7.5 20.3 9.2 12.1 3.5 7.3 14.4 14.7 21.0 22.2 24.3 17.0 10.9 8.2 8.3 40.0 16.8 7.4 14.6 10.9 24.1 22.2 22.7 35.6 6.6 10.3 25.4 16.0 16.6 5.3 24.6 76.7 13.9 20.1 23.1 13.3 32.0 16.7 7.6 19.5 14.3 13.1 9.2 16.1 26.1 35.2 13.3 10.7 27.8 42.0 44.4 34.4 28.5 55.6 32.1 24.2 36.4 13.6 18.2 28.1 27.2 16.0 29.4 23.3 4.5 31.0 29.2 15.1 11.8 18.1 32.7 37.2 23.9 12.7 21.6 14.2 18.3 19.2 14.9 29.0 43.3 28.2 35.9 35.2 37.2 31.1 30.7 37.6 29.9 36.1 30.2 4.7 35.9 34.9 49.3 34.7 17.5 20.6 20.4 19.5 24.4 20.5 20.3 20.8 19.7 20.6 19.2 20.3 21.0 37.7 22.4 22.4 10.4 29.8 66.8 35.5 58.5 47.3 51.4 41.1 50.9 18.1 28.6 31.0 38.6 18.8 76.2 49.8 61.6 45.0 38.0 4.4 28.2 31.7 33.9 26.3 57.4 12.9 39.5 59.3 34.3 25.0 43.7 24.7 36.9 32.2 24.4 40.4 47.1 10.1 58.8 54.9 24.2 72.7 5.5 51.3 29.8 32.0 2.8 32.4 42.5 30.9 9.5 14.3 37.5 43.5 46.6 28.1 37.4 47.8 38.3 25.1 54.5 65.7 31.6 44.7 44.0 50.0 54.1 80.6 28.3 47.2 28.0 56.6 25.8 C20orf173 dJ477O4.4 ENSG00000125975 "Chromosome 20 open reading frame 173" Q96LM9 20 35523186-35529652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 35.5" "Group enriched" "Detected in some" 76 "Early spermatids: 473.3;Late spermatids: 156.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA076859 Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA076859: " "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 473.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 156.5 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2orf16 DKFZp434G118 ENSG00000221843 "Chromosome 2 open reading frame 16" Q68DN1 2 27537386-27582721 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 21.4" "Cell type enriched" "Detected in some" 6 "Early spermatids: 94.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.4;SiHa: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052136, HPA056962" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 74: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA052136: AB_2681742, HPA056962: AB_2683290" "unprognostic (4.32e-2)" "unprognostic (1.08e-2)" "unprognostic (8.36e-2)" "unprognostic (3.40e-3)" "unprognostic (6.36e-2)" "unprognostic (6.17e-2)" "unprognostic (6.15e-2)" "unprognostic (3.07e-1)" "unprognostic (9.35e-2)" "unprognostic (3.79e-3)" "unprognostic (4.59e-1)" "unprognostic (2.19e-2)" "unprognostic (8.82e-2)" "unprognostic (8.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-2)" "unprognostic (8.53e-3)" 0.1 0.4 0.1 0.2 0.1 0.0 0.2 0.0 0.3 0.2 0.0 0.2 0.1 0.2 0.0 0.3 0.2 0.2 0.3 0.1 0.2 0.2 1.2 0.1 0.1 0.3 0.1 0.5 0.3 0.0 0.5 0.0 0.3 0.2 0.0 1.5 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.4 21.4 0.3 0.0 0.4 0.0 0.0 0.2 0.2 0.2 0.6 0.6 0.9 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.8 0.3 0.8 0.0 0.6 0.2 0.0 0.0 0.0 0.6 0.1 1.2 0.5 0.6 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.5 0.8 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.5 0.2 0.0 0.6 2.4 0.4 1.8 0.4 0.2 0.1 0.4 0.4 1.1 0.5 0.8 0.3 0.4 0.1 0.0 0.7 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 94.1 0.3 0.2 0.1 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.0 0.0 0.0 14.4 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2orf68 ENSG00000168887 "Chromosome 2 open reading frame 68" Q2NKX9 2 85605254-85612066 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051143 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane, Mitochondria" Nucleoli "HPA051143: AB_2681360" "unprognostic (1.71e-2)" "unprognostic (3.65e-2)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.12e-6)" "unprognostic (9.34e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.76e-6)" "unprognostic (4.24e-3)" "unprognostic (8.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.88e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (1.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.70e-2)" "unprognostic (8.81e-3)" 11.0 9.4 8.8 10.0 11.6 10.5 12.6 15.4 9.9 18.7 10.7 13.6 11.0 15.7 12.2 12.1 15.2 6.6 12.3 8.6 9.4 12.8 11.7 14.0 14.2 11.7 10.8 20.4 17.2 8.5 14.0 12.5 11.0 16.4 10.9 20.0 16.4 10.7 21.8 16.3 16.6 9.9 9.8 16.9 14.3 9.5 10.2 13.7 16.3 9.8 13.9 13.6 15.4 15.2 8.8 7.9 15.7 11.5 14.2 7.6 10.2 4.3 5.6 6.7 8.7 7.1 10.6 12.4 6.0 7.3 6.0 10.4 7.9 7.5 7.2 6.8 19.1 21.1 13.8 8.5 11.2 12.3 11.4 11.3 9.7 4.4 12.7 10.6 10.1 14.7 10.7 12.4 6.3 9.3 13.3 13.4 6.9 10.2 7.3 14.8 27.8 11.5 8.5 10.1 19.8 14.2 6.5 8.5 9.0 8.7 9.1 6.5 7.0 4.8 12.8 5.9 4.2 17.9 11.8 10.8 7.2 12.9 6.0 32.7 30.5 59.0 22.4 21.8 21.3 14.6 21.1 21.0 22.4 20.7 30.5 28.2 49.2 31.2 27.0 15.2 17.7 16.7 8.8 11.6 15.4 9.9 8.6 9.4 11.7 10.8 11.0 9.8 10.2 15.2 8.2 64.1 63.1 15.0 18.6 5.9 18.2 10.0 9.6 17.4 16.0 12.3 10.7 37.1 24.3 35.0 35.5 47.2 24.4 24.6 17.6 17.9 4.8 9.4 8.7 13.9 19.2 19.5 2.7 19.8 17.7 12.9 17.9 9.6 34.7 15.6 17.9 25.3 23.3 25.2 6.8 16.9 12.2 34.9 14.3 12.8 24.2 26.0 14.2 15.0 31.4 12.3 38.1 10.1 16.9 19.4 14.0 13.5 13.6 14.4 32.7 26.6 21.0 27.0 19.7 13.7 8.5 37.2 20.1 27.4 9.8 24.9 18.1 10.0 15.8 19.2 C3orf38 MGC26717 ENSG00000179021 "Chromosome 3 open reading frame 38" Q5JPI3 3 88149959-88168729 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 341.2;Late spermatids: 312.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 147.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034736, HPA034737" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA034736: AB_2674307, HPA034737: AB_10671505" "unprognostic (1.93e-1)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (1.48e-2)" "unprognostic (1.74e-2)" "unprognostic (2.41e-2)" "unprognostic (2.26e-3)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "prognostic favorable (3.55e-4)" "unprognostic (9.28e-3)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.95e-2)" "unprognostic (2.88e-3)" "unprognostic (1.63e-1)" "unprognostic (4.57e-2)" "unprognostic (3.67e-2)" 10.2 8.8 7.1 11.1 9.2 42.1 12.4 11.2 11.5 10.7 6.8 11.1 9.7 9.1 10.9 12.1 10.6 9.7 9.9 7.8 8.6 10.4 14.1 10.1 17.7 8.0 7.5 11.6 7.8 10.7 4.8 12.4 8.6 10.1 11.0 7.7 8.8 9.5 8.0 8.2 10.0 10.9 8.7 13.2 10.4 32.8 7.8 20.9 12.0 10.8 18.4 12.5 5.2 12.8 16.6 17.4 32.5 17.7 22.5 19.8 15.0 26.3 31.5 38.6 51.9 19.5 22.5 22.8 23.1 24.5 18.4 11.8 23.7 19.2 33.1 40.1 11.7 27.1 12.3 16.9 30.8 37.9 22.5 27.7 20.1 26.1 21.8 25.2 23.1 23.7 18.0 25.1 43.4 19.4 38.3 16.9 40.0 31.0 18.8 23.9 11.4 21.5 25.7 22.6 10.1 14.6 24.1 14.2 42.2 26.2 25.5 30.0 20.6 24.2 25.7 147.7 29.8 22.6 36.2 33.0 18.8 29.8 23.0 47.8 22.3 24.1 16.8 32.4 21.4 26.0 15.3 17.2 23.5 22.3 15.1 15.6 9.7 23.4 27.4 16.2 20.5 21.6 7.1 9.2 11.2 11.5 7.8 8.6 8.0 7.5 8.6 8.7 7.8 12.8 13.3 19.2 7.5 5.9 30.9 11.7 18.8 19.9 14.2 21.6 11.0 9.5 6.9 8.6 16.7 5.5 22.9 21.6 24.4 13.9 19.6 16.7 341.2 14.4 13.3 10.8 16.2 23.5 9.7 13.7 22.7 17.3 11.7 10.2 14.0 14.2 11.4 7.5 26.7 6.7 9.1 13.3 14.2 23.9 25.1 312.0 16.4 24.0 16.0 6.5 28.0 23.2 23.7 10.1 15.0 15.3 19.3 15.1 17.5 18.6 16.1 14.5 21.2 24.8 13.1 14.9 16.6 75.7 12.2 14.9 14.1 25.6 24.6 18.1 11.1 22.5 C3orf49 ENSG00000163632 "Chromosome 3 open reading frame 49" Q96BT1 3 63819299-63848636 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.7" "Group enriched" "Detected in some" 6 "Early spermatids: 19.5;Late spermatids: 34.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.0;MCF7: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA053582 Uncertain Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Vesicles, Centrosome" "HPA053582: AB_2682199" "unprognostic (2.90e-1)" "unprognostic (2.63e-1)" "unprognostic (4.81e-2)" "unprognostic (1.64e-1)" "unprognostic (1.07e-1)" "unprognostic (5.27e-3)" "unprognostic (1.79e-1)" "unprognostic (2.14e-2)" "unprognostic (9.29e-3)" "unprognostic (1.72e-1)" "unprognostic (5.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.61e-3)" "unprognostic (1.02e-1)" "unprognostic (7.68e-2)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" 0.0 0.2 0.1 0.2 0.4 0.6 0.0 1.2 1.7 0.1 0.0 0.1 0.6 0.3 0.0 0.7 0.1 0.2 0.3 0.2 0.0 0.1 0.3 0.3 0.3 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.1 0.0 1.4 0.3 0.0 1.1 0.9 0.3 0.0 0.0 0.2 0.2 1.3 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.2 0.7 0.4 0.4 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.7 0.3 1.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.5 0.6 0.8 2.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.4 0.0 1.8 0.4 0.4 0.5 0.4 0.1 0.6 0.4 0.9 0.0 0.4 0.4 0.3 0.1 0.9 0.1 0.1 0.2 0.3 0.5 0.3 0.4 0.6 0.7 0.2 0.9 0.1 0.9 1.4 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.4 1.2 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.2 0.1 0.5 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 19.5 0.2 0.2 0.1 0.0 0.0 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 34.4 0.3 0.0 0.0 1.0 0.1 0.2 0.0 1.5 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.3 0.2 0.3 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.3 C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 17.4;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 129.6;Pancreatic endocrine cells: 82.8;Prostatic glandular cells: 75.6;Syncytiotrophoblasts: 75.0;Urothelial cells: 132.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.4;U-698: 30.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" 1.2 1.0 0.1 1.2 0.2 0.6 2.7 0.2 0.3 0.7 0.2 7.5 3.3 0.9 0.0 2.6 0.7 5.0 4.0 0.2 0.1 4.8 0.3 3.8 1.2 0.0 0.1 0.2 17.4 0.0 2.0 3.3 0.1 1.7 13.7 0.1 3.8 3.4 0.5 26.3 5.2 0.9 0.1 0.7 13.7 0.9 0.3 6.6 7.6 0.1 2.0 5.8 1.6 0.1 11.0 2.0 4.2 0.0 0.6 0.0 1.8 15.5 6.7 10.1 11.3 26.4 10.1 0.4 1.9 3.1 4.4 8.7 6.1 0.3 19.4 0.0 2.8 7.9 1.8 1.9 4.6 0.0 0.1 0.6 8.7 5.2 15.0 5.4 2.2 0.0 2.8 2.8 7.5 1.7 0.3 0.0 12.3 7.9 0.6 0.3 13.2 0.0 18.1 16.5 0.5 0.9 2.4 5.2 6.3 6.8 9.5 0.0 5.8 3.6 5.5 0.0 0.0 3.9 0.0 30.1 2.7 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.8 16.0 10.0 0.3 1.6 32.5 129.6 10.0 45.5 0.0 14.8 3.3 2.1 4.3 19.3 18.4 0.0 18.1 0.7 30.4 0.0 26.3 24.2 24.8 3.1 3.5 11.9 0.0 3.2 35.9 25.6 4.7 64.2 44.1 0.0 0.4 0.4 0.0 1.9 0.0 0.6 56.6 8.2 0.3 2.7 23.3 0.3 1.0 1.8 1.0 2.6 0.0 0.0 0.5 0.3 82.8 30.7 0.4 4.6 75.6 7.8 2.1 14.8 0.0 0.0 4.6 4.7 3.2 5.3 44.0 33.5 75.0 2.0 3.0 8.9 132.5 C3orf56 FLJ40141 ENSG00000214324 "Chromosome 3 open reading frame 56" Q8N813 3 127193131-127198185 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055395 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Centrosome, Cytosol" "HPA055395: " "unprognostic (1.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C7orf26 MGC2718 ENSG00000146576 "Chromosome 7 open reading frame 26" Q96N11 7 6590021-6608726 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042899, HPA052175" Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nucleoli, Intermediate filaments, Cytosol" "HPA042899: AB_2678218, HPA052175: AB_2681750" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (4.51e-2)" "unprognostic (2.50e-2)" "unprognostic (2.18e-2)" "unprognostic (5.22e-2)" "unprognostic (4.28e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "prognostic favorable (6.95e-5)" "unprognostic (4.72e-2)" "unprognostic (2.26e-3)" "unprognostic (4.41e-1)" "unprognostic (1.03e-2)" "unprognostic (3.40e-3)" "unprognostic (1.55e-1)" 18.1 18.9 16.9 12.2 18.2 21.3 18.9 15.9 18.5 23.0 15.0 21.6 12.6 23.3 6.5 16.5 22.2 9.3 17.6 16.3 16.2 19.6 21.5 17.2 17.3 18.8 17.2 19.9 21.7 10.1 17.0 7.2 16.9 22.9 7.1 3.8 16.6 9.8 21.9 21.4 18.6 11.1 16.0 27.2 20.0 17.3 17.3 18.5 19.0 10.2 10.9 20.9 17.1 20.4 21.5 17.6 12.0 28.5 19.3 10.7 15.8 12.6 10.9 17.8 10.9 16.5 8.7 25.2 16.0 9.4 33.7 23.3 16.2 11.5 8.1 9.9 23.3 9.4 11.5 17.6 22.5 22.7 29.0 12.4 17.0 10.7 11.2 9.4 19.6 26.7 25.1 18.6 10.7 36.1 19.9 46.9 24.0 10.6 23.2 40.1 9.5 21.5 11.6 18.5 15.7 29.2 12.2 39.9 17.3 12.5 18.3 33.8 14.2 14.7 48.2 16.3 27.9 22.5 23.8 23.8 9.9 24.9 44.3 0.5 1.5 2.2 2.0 1.5 2.6 1.7 2.4 2.6 1.1 1.6 2.4 2.0 1.4 1.6 1.6 2.9 2.7 0.9 16.9 18.2 15.9 18.5 16.3 16.2 18.8 17.2 16.9 16.0 17.3 20.4 12.9 9.6 8.6 11.1 13.7 15.2 8.8 4.6 13.1 7.1 14.2 14.5 6.0 12.8 6.1 1.8 6.2 11.6 23.6 11.8 0.0 8.9 8.2 9.9 12.6 12.8 12.6 4.2 9.5 10.2 10.6 11.2 10.7 8.9 1.3 16.0 12.5 7.4 13.4 5.0 8.3 12.5 8.2 11.3 10.2 3.5 8.1 12.9 7.2 7.5 8.4 6.7 18.6 9.5 13.2 10.2 9.8 8.6 10.9 10.9 8.5 8.0 5.3 6.5 6.6 12.0 14.5 11.9 13.5 11.7 12.8 9.7 17.5 14.0 11.6 7.6 C7orf31 ENSG00000153790 "Chromosome 7 open reading frame 31" Q8N865 7 25134692-25180356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 65.6" "Group enriched" "Detected in many" 17 "Early spermatids: 423.9;Late spermatids: 881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 19.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA020346 Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" Cytosol "HPA020346: AB_1845758" "unprognostic (3.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.01e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (1.81e-4)" "unprognostic (1.19e-1)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (2.90e-1)" "unprognostic (1.06e-1)" "unprognostic (3.12e-3)" "unprognostic (8.26e-3)" "unprognostic (1.63e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.15e-2)" 3.1 7.8 1.4 3.2 2.1 1.9 2.9 3.2 2.0 3.4 1.7 6.8 4.4 3.8 1.7 2.5 3.5 2.5 2.2 1.4 2.3 2.8 1.3 2.6 3.3 2.3 1.5 5.4 2.1 3.9 2.2 1.3 2.1 2.8 4.6 2.7 3.5 2.5 0.9 2.3 3.9 3.0 1.7 4.0 4.5 65.6 1.9 4.3 4.1 1.1 3.9 3.8 2.8 2.4 3.2 2.1 5.2 5.4 2.0 0.9 2.5 1.3 4.7 3.7 5.5 4.4 3.0 8.1 2.0 2.6 16.5 1.2 5.3 1.5 4.0 3.8 5.1 4.1 0.3 5.8 4.4 7.0 8.5 3.2 4.6 3.0 0.8 2.8 0.7 6.9 5.7 4.7 1.3 0.0 5.5 7.5 2.1 6.4 2.3 8.7 5.5 1.3 2.7 3.8 1.3 4.1 1.2 5.2 5.1 6.7 0.9 9.2 0.9 2.6 6.6 0.1 2.2 19.3 7.0 11.6 0.7 5.7 10.4 0.4 0.4 0.8 0.6 0.2 0.7 1.0 0.3 0.4 0.6 0.6 0.9 0.7 0.0 1.0 0.3 1.9 1.0 0.3 1.4 2.1 3.2 2.0 1.4 2.3 2.3 1.5 2.1 1.7 1.9 2.4 2.6 0.0 5.0 2.6 8.4 1.1 2.4 0.8 2.8 1.1 1.6 1.8 1.6 4.3 0.3 0.0 0.0 3.4 7.0 6.5 3.9 1.9 423.9 0.9 1.9 2.5 4.2 3.0 0.8 3.9 2.9 2.5 4.6 1.2 0.0 3.4 2.2 0.8 2.5 0.0 1.2 3.5 0.0 6.1 3.1 881.6 7.2 3.8 3.6 7.5 6.1 7.7 13.4 0.5 4.3 3.9 6.1 5.3 8.9 1.3 2.2 0.8 3.2 0.8 0.0 3.0 2.8 37.3 15.2 2.5 0.6 2.3 6.6 2.4 7.0 1.3 C8orf34 "vest-1, VEST1" ENSG00000165084 "Chromosome 8 open reading frame 34" Q49A92 8 68330955-68819023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.2;fallopian tube: 9.1;parathyroid gland: 7.4" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 396.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.3;HEK 293: 2.3;LHCN-M2: 2.7;RH-30: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044420, HPA053065" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus" No NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA044420: AB_10963791, HPA053065: AB_2682030" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (3.07e-1)" "unprognostic (2.85e-2)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (1.74e-1)" "unprognostic (8.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.80e-4)" "unprognostic (5.21e-2)" "unprognostic (8.87e-2)" "unprognostic (2.84e-4)" "unprognostic (1.33e-1)" 2.7 0.3 4.0 0.2 5.4 0.5 0.7 3.6 3.9 2.1 2.0 0.2 0.2 0.6 0.6 1.0 9.1 0.6 0.7 6.2 3.8 0.4 0.2 2.5 0.2 6.4 10.2 0.4 1.1 7.4 1.7 0.3 4.6 2.1 0.3 1.0 0.6 1.0 0.3 0.9 0.2 0.1 4.0 0.2 0.8 0.7 6.7 0.8 0.4 0.9 0.2 0.4 0.2 6.1 0.1 0.0 0.3 0.1 0.6 1.0 0.1 0.9 2.3 0.3 0.3 0.1 0.2 0.1 0.3 0.5 0.1 0.1 0.1 0.3 0.1 0.0 2.3 0.3 0.5 0.2 0.1 0.0 0.2 0.1 0.3 0.4 0.8 0.1 0.0 0.3 0.1 0.4 2.7 0.3 0.0 0.2 1.0 0.0 0.0 0.1 2.7 0.0 0.2 0.2 0.5 0.0 0.1 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.2 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.4 0.5 0.1 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.3 0.2 0.3 0.5 0.2 0.1 0.4 0.1 0.1 4.0 5.4 3.6 3.9 6.2 3.8 6.4 10.2 4.6 4.0 6.7 6.1 0.2 16.0 18.7 9.4 0.0 1.7 0.8 0.2 0.0 1.5 0.2 0.0 1.2 0.0 3.9 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.5 26.4 0.7 0.5 0.0 0.0 79.2 0.0 0.3 1.9 0.0 4.3 1.3 0.1 0.0 0.0 0.3 0.0 396.6 0.1 0.0 0.0 1.2 1.3 0.3 0.4 1.8 3.7 0.1 0.0 0.0 9.5 10.1 0.5 0.0 0.4 0.0 0.8 0.0 0.0 20.8 0.7 0.0 0.6 1.7 0.6 0.4 0.1 0.9 0.4 0.4 0.2 0.0 0.4 C8orf37 "BBS21, CORD16, FAP418, FLJ30600, MOT25, RP64" ENSG00000156172 "Chromosome 8 open reading frame 37" Q96NL8 8 95244913-95269201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Cone-rod dystrophy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024198 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Plasma membrane, Cell Junctions" "HPA024198: AB_1845775" "unprognostic (7.90e-2)" "unprognostic (1.98e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.72e-3)" "unprognostic (4.20e-3)" "unprognostic (2.04e-2)" "unprognostic (8.94e-2)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (6.11e-3)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (6.72e-3)" "unprognostic (2.02e-1)" "unprognostic (1.33e-2)" "unprognostic (3.29e-1)" 1.7 1.8 1.7 1.2 1.9 0.9 2.3 2.3 2.2 2.3 3.2 1.0 0.9 2.4 3.1 1.0 3.9 1.4 2.7 1.7 1.8 2.4 1.8 1.5 2.2 2.3 2.9 4.8 1.2 3.5 2.3 1.8 2.2 2.0 0.9 5.0 1.5 1.7 1.1 1.5 1.0 2.3 2.7 1.7 1.1 1.7 1.8 2.4 2.4 1.8 1.9 1.2 1.4 2.9 2.8 4.5 3.6 1.9 1.2 3.3 1.0 1.2 2.7 1.5 2.0 0.7 6.0 5.6 2.8 2.0 3.8 2.3 1.5 3.1 3.3 1.8 1.4 4.4 2.7 2.0 1.4 0.9 2.3 3.3 1.4 1.8 5.0 3.9 2.3 3.3 2.3 3.2 2.0 2.1 4.8 1.1 1.1 5.6 3.0 2.5 1.9 1.4 3.4 1.2 3.5 3.4 2.5 0.5 2.1 2.7 4.2 0.8 2.0 1.9 2.4 1.6 1.2 2.9 3.0 3.8 3.6 2.1 2.4 0.3 0.3 0.1 0.2 0.2 0.5 0.4 0.3 0.3 0.5 0.8 0.3 0.5 0.4 0.7 0.1 0.2 0.1 0.2 1.7 1.9 2.3 2.2 1.7 1.8 2.3 2.9 2.2 2.7 1.8 2.9 2.4 3.2 2.6 6.8 2.5 0.9 3.7 2.9 4.0 2.7 1.3 2.4 5.3 0.0 3.3 7.3 2.1 2.5 1.8 0.1 7.9 1.8 10.2 3.4 1.3 1.5 0.0 0.4 6.8 2.7 2.9 2.8 1.1 1.0 0.0 1.9 1.1 3.8 1.3 3.3 5.2 0.1 2.0 1.6 1.2 8.7 3.1 0.8 1.8 1.9 1.8 5.3 0.0 8.5 5.7 1.2 0.2 3.0 0.7 1.9 0.1 4.7 7.9 4.1 0.0 2.5 4.2 6.0 3.5 0.9 1.8 0.8 1.1 3.0 0.5 1.8 C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 20.8" "Group enriched" "Detected in some" 26 "Early spermatids: 268.6;Late spermatids: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "HeLa: 1.3" "Not detected" "Not detected" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.30e-3)" "unprognostic (7.49e-2)" "unprognostic (2.75e-2)" "unprognostic (3.37e-1)" "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (1.49e-1)" "unprognostic (2.01e-6)" "unprognostic (9.43e-2)" "unprognostic (1.92e-1)" "unprognostic (9.64e-2)" "unprognostic (2.10e-1)" 0.1 0.4 0.3 0.4 0.2 2.6 0.2 1.4 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.5 0.5 0.6 0.2 0.1 0.1 0.0 0.9 0.6 0.1 0.1 0.6 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.2 0.3 20.8 0.5 0.1 0.2 0.1 0.0 0.0 0.0 1.3 0.2 0.8 0.0 0.4 0.0 0.4 0.3 0.2 0.0 0.0 0.2 0.0 0.6 0.8 0.2 0.2 0.5 0.2 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.2 0.1 0.2 0.2 0.1 0.6 0.1 0.0 0.0 0.3 0.9 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.6 0.1 0.2 0.4 0.1 0.3 0.0 0.1 0.4 0.8 1.6 0.2 0.3 0.6 0.1 0.1 0.1 0.1 1.2 0.2 0.1 0.1 0.5 0.3 0.2 0.2 0.1 1.5 0.3 0.2 1.4 0.9 0.2 0.2 0.5 0.6 0.6 0.0 0.5 1.3 0.3 0.0 0.0 9.8 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 268.6 0.4 0.5 0.7 0.0 0.0 4.8 0.0 0.1 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 244.8 2.8 0.1 1.8 1.0 0.1 0.4 2.1 6.6 9.7 0.1 0.0 0.7 0.4 0.3 0.0 0.1 0.0 0.1 0.0 1.3 0.7 1.8 1.9 0.0 0.1 0.1 0.2 0.3 0.1 0.2 C9orf40 FLJ10110 ENSG00000135045 "Chromosome 9 open reading frame 40" Q8IXQ3 9 74946583-74952912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.9;Cardiomyocytes: 45.0;Erythroid cells: 39.2;Spermatocytes: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042167 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA 230000 "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 44: HDLM-2 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Cytosol" Centrosome "HPA042167: AB_10797382" "unprognostic (2.10e-1)" "unprognostic (7.65e-2)" "unprognostic (2.94e-1)" "unprognostic (7.65e-2)" "unprognostic (6.27e-2)" "unprognostic (4.18e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (6.12e-2)" "unprognostic (1.11e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" "unprognostic (6.15e-3)" "unprognostic (6.78e-3)" "unprognostic (3.74e-2)" "unprognostic (4.21e-2)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" 4.9 2.1 6.9 4.3 6.8 6.2 4.4 6.8 9.6 4.2 4.5 5.8 8.4 3.7 1.5 3.9 3.1 1.6 2.9 7.1 7.2 2.6 3.1 2.1 4.7 7.4 6.9 2.6 2.3 2.9 3.1 3.7 7.2 2.7 5.1 7.9 2.2 2.4 3.1 2.2 11.3 2.7 7.3 3.9 2.6 11.8 6.8 4.3 2.1 2.5 4.7 4.2 4.2 8.4 29.6 6.3 16.3 6.6 6.5 8.2 30.2 23.0 7.1 15.7 16.8 1.8 9.0 26.5 6.7 5.8 26.2 8.6 12.9 1.3 24.9 36.0 19.9 14.1 11.2 11.3 5.2 17.2 21.5 4.1 8.5 8.7 6.2 6.3 4.9 19.1 20.3 17.5 20.7 8.3 30.3 19.9 19.2 15.4 19.2 28.0 12.8 6.5 6.7 7.1 17.7 7.8 10.1 8.5 7.3 14.3 10.3 13.1 6.4 14.1 15.9 19.5 20.4 33.2 26.7 17.0 10.7 19.0 15.5 0.6 0.1 2.1 0.3 0.1 0.1 0.8 0.3 0.3 0.1 0.5 0.7 0.4 0.1 0.0 0.2 0.3 0.4 0.1 6.9 6.8 6.8 9.6 7.1 7.2 7.4 6.9 7.2 7.3 6.8 8.4 29.9 3.2 0.5 2.3 5.8 2.4 4.4 1.1 3.4 9.7 6.0 6.2 45.0 0.0 0.6 3.7 8.4 20.9 3.2 13.4 1.9 3.3 12.0 2.9 6.2 12.1 1.2 39.2 5.8 3.1 24.9 5.9 2.6 6.4 0.0 3.1 8.2 3.8 11.3 1.7 4.6 7.9 0.0 4.2 3.7 2.9 4.4 3.5 1.8 6.5 2.6 4.8 2.1 1.5 4.0 2.5 7.3 5.3 4.2 5.4 20.3 2.2 1.0 16.4 0.0 3.8 5.8 42.2 10.6 7.1 5.3 12.3 4.8 9.2 17.0 3.9 C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.7;myeloid DC: 25.2;neutrophil: 34.3;non-classical monocyte: 36.9" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.3;monocytes: 44.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Yes NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "Midbody ring" "HPA023873: AB_1845834" "unprognostic (1.78e-2)" "unprognostic (5.01e-2)" "unprognostic (7.63e-2)" "unprognostic (9.78e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-3)" "unprognostic (2.45e-1)" "unprognostic (2.05e-2)" "unprognostic (2.16e-2)" "unprognostic (9.81e-2)" "unprognostic (1.44e-2)" "unprognostic (9.29e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-2)" "unprognostic (9.13e-2)" 11.7 12.1 9.5 16.6 9.5 25.3 9.4 21.0 12.5 9.8 12.4 8.8 6.8 12.0 11.3 7.6 16.0 10.2 9.3 9.7 13.5 7.0 16.0 17.7 9.2 14.6 11.9 24.2 9.6 6.9 16.2 12.1 12.5 14.2 7.8 31.3 6.7 5.8 14.9 8.8 8.3 8.6 12.4 16.8 7.8 17.6 11.3 11.1 13.1 9.9 8.8 9.2 8.5 14.5 4.4 3.7 28.7 4.4 5.7 7.0 4.4 5.9 4.9 3.5 1.8 0.4 1.4 10.2 3.7 5.3 7.5 3.1 9.4 7.2 2.5 19.8 3.6 4.9 11.0 3.0 8.9 3.4 5.2 7.3 8.6 0.8 16.1 3.5 7.6 11.1 9.8 18.6 4.3 0.8 6.6 5.0 14.2 6.8 16.0 2.4 9.5 5.1 2.8 3.3 9.9 24.4 4.0 4.4 3.7 10.9 3.7 2.9 6.6 0.0 14.5 8.6 4.0 4.8 15.8 6.8 11.4 11.0 3.8 24.3 32.0 2.4 1.9 44.7 3.3 3.4 2.7 2.5 25.2 2.5 4.6 2.9 34.3 4.3 36.9 3.9 4.0 10.0 9.5 9.5 21.0 12.5 9.7 13.5 14.6 11.9 12.5 12.4 11.3 14.5 15.4 16.0 14.7 19.2 43.2 35.9 50.7 15.0 26.2 22.1 7.2 6.6 15.6 4.3 15.2 7.3 20.9 21.2 11.7 5.0 1.9 8.4 2.6 94.4 11.8 15.0 11.4 3.0 53.0 9.3 7.3 18.7 16.8 57.6 16.5 18.4 8.2 9.3 25.8 11.8 58.9 12.5 10.2 71.9 127.8 4.2 6.2 94.8 19.6 42.2 58.2 45.2 3.1 30.2 60.9 8.6 11.1 3.8 10.7 30.0 4.1 5.4 80.7 27.5 0.0 17.5 20.6 29.2 20.9 15.2 29.1 34.6 18.2 7.9 5.1 37.6 C9orf85 MGC61599 ENSG00000155621 "Chromosome 9 open reading frame 85" Q96MD7 9 71911510-71986054 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050767, HPA076627" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA050767: AB_2681229, HPA076627: " "unprognostic (7.81e-2)" "unprognostic (2.80e-1)" "unprognostic (6.21e-2)" "unprognostic (3.04e-1)" "unprognostic (2.89e-2)" "unprognostic (2.87e-2)" "unprognostic (1.99e-2)" "unprognostic (2.34e-1)" "unprognostic (1.01e-1)" "unprognostic (3.05e-1)" "unprognostic (1.27e-1)" "unprognostic (3.48e-1)" "unprognostic (1.10e-2)" "unprognostic (8.10e-2)" "unprognostic (6.60e-2)" "unprognostic (4.02e-1)" "unprognostic (6.18e-2)" 7.5 6.6 7.5 6.4 9.0 6.0 8.9 8.2 7.8 9.2 5.0 7.8 11.9 7.3 5.7 9.9 6.5 6.8 6.2 7.0 7.2 7.1 7.9 5.0 8.7 8.5 7.6 9.5 7.8 4.9 5.9 8.4 8.2 7.2 7.5 6.3 8.9 5.0 8.7 11.2 8.2 6.3 6.5 6.7 6.8 5.4 8.2 8.5 8.5 8.4 8.0 9.8 8.4 12.9 11.6 7.5 12.6 10.4 12.7 23.4 12.8 13.8 22.0 11.1 11.0 1.5 6.4 18.5 6.9 12.1 11.7 20.1 13.4 13.6 15.4 12.9 6.5 11.3 10.3 9.5 13.9 16.7 8.5 19.2 18.2 11.4 25.2 17.5 13.8 17.1 13.8 11.8 14.5 5.7 20.4 11.8 11.6 17.8 17.6 11.6 22.4 0.5 16.3 16.7 10.1 13.9 7.0 17.8 25.0 13.8 6.0 9.6 12.1 10.2 13.3 23.7 10.6 12.0 21.7 8.5 14.0 12.6 6.5 15.1 6.6 10.6 9.9 7.5 10.5 8.7 8.4 8.5 7.3 8.6 10.2 10.8 7.6 13.0 6.8 10.5 8.4 7.4 7.5 9.0 8.2 7.8 7.0 7.2 8.5 7.6 8.2 6.5 8.2 12.9 19.2 6.4 17.0 35.6 15.7 7.6 13.6 12.8 25.6 10.9 13.9 22.9 14.0 8.6 12.6 5.5 8.4 20.3 18.4 25.2 21.5 14.2 10.8 9.4 19.7 15.0 6.6 8.2 27.4 19.9 19.0 14.1 19.9 10.8 18.4 13.7 18.5 9.7 14.8 5.0 19.2 23.4 10.2 16.1 8.9 7.5 20.8 15.2 3.6 24.4 17.7 12.5 33.0 44.2 112.1 17.8 30.6 13.2 9.5 12.7 29.3 22.8 8.4 13.0 13.1 19.3 17.3 20.6 14.6 23.2 9.8 10.8 16.2 21.9 16.8 27.0 CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Proximal enterocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 15.6;OE19: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 27000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" 1.8 2.1 1.2 1.2 1.2 0.3 2.3 1.4 1.3 2.1 0.7 2.5 12.0 0.9 0.6 5.0 1.1 5.4 3.6 1.0 1.7 5.7 3.7 2.4 0.6 0.9 1.5 1.1 1.1 9.0 2.9 0.3 0.8 1.2 3.0 2.3 4.8 0.7 0.4 5.6 14.6 0.8 0.6 0.7 5.9 0.7 1.1 0.7 5.0 0.3 2.9 2.1 2.5 1.3 0.2 0.4 0.8 0.1 0.5 0.6 0.4 1.0 1.1 0.1 2.9 7.2 5.4 0.4 0.5 1.2 6.0 2.3 2.2 2.9 0.2 1.6 0.9 15.6 2.0 6.7 1.4 0.2 0.6 2.2 0.5 0.2 1.2 1.8 1.6 0.6 4.0 2.9 2.6 0.0 0.3 0.2 0.4 30.6 0.4 0.2 2.2 0.1 8.1 0.3 0.2 0.0 0.5 0.0 1.6 1.0 0.5 0.8 1.5 2.8 3.9 0.1 1.6 1.1 0.6 1.9 5.7 2.2 2.6 0.7 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.2 1.2 1.2 1.4 1.3 1.0 1.7 0.9 1.5 0.8 0.6 1.1 1.3 1.7 3.2 12.4 7.2 2.9 1.8 2.7 2.7 3.4 1.8 7.0 4.7 6.4 4.3 10.5 12.9 33.3 0.3 2.1 12.3 9.8 4.0 11.3 4.7 2.5 2.7 4.8 3.2 12.2 1.6 0.3 2.9 9.7 7.7 0.0 0.3 8.6 5.8 1.1 0.0 13.7 4.3 2.0 2.5 3.3 13.1 0.0 3.0 5.4 1.9 1.0 1.9 8.2 16.1 4.4 4.4 4.3 0.0 6.9 1.9 52.6 21.0 9.5 5.1 0.0 8.1 1.9 1.3 2.1 9.1 3.1 0.3 2.2 1.0 5.4 2.4 CABCOCO1 "bA63A2.1, C10orf107, Em:AC022398.2, MGC44593" ENSG00000183346 "Ciliary associated calcium binding coiled-coil 1" Q8IVU9 10 61662929-61766766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.6;testis: 15.5" "Group enriched" "Detected in some" 10 "Endometrial ciliated cells: 60.4;Respiratory ciliated cells: 88.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "MOLT-4: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041398 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Centrosome "Nucleoplasm, Cytosol" "HPA041398: AB_10794374" "unprognostic (1.89e-3)" "unprognostic (7.37e-2)" "unprognostic (2.23e-1)" "prognostic favorable (1.79e-4)" "prognostic unfavorable (4.88e-4)" "unprognostic (1.02e-1)" "unprognostic (2.55e-1)" "unprognostic (5.52e-2)" "unprognostic (4.43e-2)" "unprognostic (3.31e-1)" "unprognostic (1.16e-1)" "unprognostic (1.26e-2)" "unprognostic (3.46e-1)" "unprognostic (1.52e-3)" "unprognostic (2.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.33e-2)" 1.0 0.5 4.2 0.2 4.2 0.0 1.2 3.5 3.9 4.2 5.9 1.2 0.3 3.5 0.5 0.3 26.6 0.8 0.2 4.4 4.6 1.8 0.3 4.1 0.0 6.8 8.9 0.2 0.5 2.9 4.2 0.8 7.2 4.1 0.6 0.9 1.0 2.5 0.1 0.3 0.5 0.7 8.3 1.0 0.5 15.5 4.0 0.1 0.7 0.0 0.1 0.4 0.6 7.8 0.0 0.2 0.1 0.0 0.0 2.5 0.0 0.4 1.7 0.3 0.6 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 2.6 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.1 1.0 0.9 0.5 0.1 0.0 0.1 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 5.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 3.5 3.9 4.4 4.6 6.8 8.9 7.2 8.3 4.0 7.8 1.9 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.5 0.0 0.0 7.4 3.7 0.0 0.3 0.0 0.0 0.0 0.8 0.0 60.4 4.1 0.4 0.0 0.0 0.0 0.2 0.2 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 88.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.0 CABLES2 "C20orf150, dJ908M14.2, ik3-2" ENSG00000149679 "Cdk5 and Abl enzyme substrate 2" Q9BTV7 20 62388632-62407285 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.0" "Cell type enhanced" "Detected in many" "Early spermatids: 51.3;Late spermatids: 25.6;Spermatocytes: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052138 Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear bodies" "Nucleoplasm, Cell Junctions" "HPA052138: AB_2681743" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.26e-5)" "unprognostic (1.45e-2)" "unprognostic (1.51e-1)" "unprognostic (2.71e-2)" "unprognostic (5.07e-2)" "unprognostic (5.37e-3)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.09e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (1.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.67e-1)" "unprognostic (2.94e-2)" 2.4 3.0 6.8 4.2 7.2 8.1 2.8 11.5 9.1 3.9 3.5 4.4 2.9 3.5 2.6 3.2 4.8 2.2 10.6 7.1 7.4 2.6 4.0 2.9 5.1 7.9 6.6 4.3 3.2 3.9 5.9 2.8 7.8 4.3 3.2 5.6 3.3 3.1 5.8 4.3 4.4 3.3 5.9 4.2 4.0 31.0 7.5 5.3 5.1 4.1 4.4 3.7 3.3 7.2 16.3 12.0 20.4 20.9 3.1 4.4 2.8 9.2 8.9 24.8 11.4 43.6 9.1 16.3 7.6 5.9 33.9 10.1 12.6 6.0 9.6 7.3 6.9 19.0 6.3 10.6 5.5 7.8 9.4 2.7 6.7 7.1 2.6 4.4 5.8 20.8 4.9 13.9 5.6 20.0 20.6 6.2 6.8 16.4 13.7 28.1 17.2 7.1 3.7 10.6 11.1 16.8 13.3 17.4 3.6 7.6 11.9 11.7 6.0 22.7 6.8 30.3 9.5 13.3 11.7 19.4 20.4 8.8 12.1 0.0 0.2 0.0 0.7 0.3 0.4 0.5 0.4 0.5 0.3 0.2 0.2 0.3 0.2 0.4 0.3 0.2 1.3 0.1 6.8 7.2 11.5 9.1 7.1 7.4 7.9 6.6 7.8 5.9 7.5 7.2 1.5 3.2 1.7 2.0 2.1 0.9 0.5 1.7 2.8 6.0 2.9 2.4 10.7 2.8 2.5 0.0 4.2 1.3 3.1 3.5 1.9 2.2 51.3 1.1 1.2 1.6 3.5 1.7 4.4 2.4 0.7 2.6 3.6 2.2 0.0 5.3 2.2 1.4 2.1 13.5 5.2 4.1 0.0 1.6 3.0 25.6 1.8 2.0 0.0 1.0 1.0 1.9 1.0 3.5 3.3 2.1 2.3 3.4 2.5 0.7 1.8 0.7 0.2 3.4 0.0 3.0 1.3 21.8 6.9 1.3 2.0 2.3 2.0 1.0 2.8 0.6 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 188.7;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 34.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;NB-4: 1.0;NTERA-2: 1.1;U-266/70: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.0 1.0 33.5 0.6 30.5 1.2 0.0 0.0 34.6 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.7 0.0 0.3 42.8 3.4 1.3 0.0 0.1 0.4 4.6 6.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.2 9.7 0.4 0.1 1.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.5 30.5 0.0 34.6 42.8 3.4 4.6 6.2 0.9 9.7 3.8 1.1 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.4 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 116.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.5 0.0 0.2 0.0 73.9 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CACTIN "C19orf29, fSAPc, NY-REN-24" ENSG00000105298 "Cactin, spliceosome C complex subunit" Q8WUQ7 19 3610645-3626815 "Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042504, HPA042548" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear speckles" Cytosol "HPA042504: AB_10797501, HPA042548: AB_10794760" "unprognostic (1.18e-1)" "unprognostic (7.90e-3)" "unprognostic (1.09e-1)" "prognostic favorable (3.69e-5)" "unprognostic (5.93e-2)" "unprognostic (2.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.01e-2)" "unprognostic (3.84e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (7.22e-3)" "unprognostic (3.88e-2)" "unprognostic (4.98e-3)" "unprognostic (5.78e-2)" "unprognostic (3.08e-2)" "unprognostic (5.55e-3)" 14.6 14.2 20.6 7.8 19.6 10.0 14.8 19.4 24.0 15.7 16.6 15.4 6.2 16.7 2.6 15.4 16.8 3.0 16.3 20.3 18.8 17.0 19.9 12.3 7.6 21.1 19.6 24.7 17.3 4.2 13.3 4.6 19.1 17.2 3.2 4.6 13.2 4.2 19.4 17.8 15.2 2.9 18.5 18.4 15.8 18.2 19.8 8.7 15.3 6.1 4.4 16.5 14.6 20.1 22.2 12.5 10.3 17.9 7.4 7.2 15.6 15.4 6.3 9.1 10.2 12.5 9.7 18.4 12.9 9.7 10.6 20.4 10.8 12.9 5.5 18.7 14.8 11.4 19.2 15.1 10.3 15.7 15.9 7.1 12.2 8.4 5.8 5.4 13.2 15.6 25.9 19.8 4.9 13.3 28.0 13.5 22.0 13.4 14.8 29.4 13.5 17.5 8.5 11.0 14.2 19.9 17.4 12.1 13.3 5.5 9.8 17.7 17.2 12.3 15.5 27.0 27.4 30.3 21.6 20.7 15.2 24.8 16.8 0.0 0.4 0.0 1.2 1.0 0.4 0.6 0.5 0.5 0.3 0.6 0.6 0.8 0.2 0.3 0.1 1.4 0.5 0.4 20.6 19.6 19.4 24.0 20.3 18.8 21.1 19.6 19.1 18.5 19.8 20.1 7.4 0.0 2.7 5.9 6.3 6.0 4.1 2.8 5.7 5.1 6.9 7.1 3.1 5.7 2.2 1.8 2.1 3.6 7.2 6.9 0.0 5.1 3.3 6.7 5.8 5.3 1.2 7.4 3.9 4.9 5.2 5.1 9.2 7.4 4.5 8.5 3.3 4.8 5.1 0.0 4.1 5.8 2.0 3.9 6.5 4.5 5.9 5.3 1.8 3.7 6.1 6.0 8.2 2.5 5.8 5.2 4.4 5.7 6.0 6.0 3.6 3.1 2.4 6.2 0.0 7.2 6.4 10.8 8.8 7.9 8.0 3.3 5.6 7.6 6.1 3.6 CALCR CTR ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;kidney: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.5;Late spermatids: 7.7;Microglial cells: 15.9;Skeletal myocytes: 46.0" "Cancer enriched" "Detected in single" 5 "renal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.6;SuSa: 2.9;T-47d: 2.7" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: AB_10602339, HPA061428: AB_2732661" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.43e-1)" "unprognostic (7.73e-5)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (8.70e-2)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (2.71e-3)" "unprognostic (1.46e-3)" "unprognostic (1.69e-1)" "unprognostic (2.49e-4)" "unprognostic (1.05e-2)" 0.1 0.2 1.6 0.0 0.5 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 5.8 1.5 0.0 0.2 0.0 1.8 1.6 0.2 0.0 0.0 0.1 0.6 3.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 2.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.2 0.0 5.8 1.8 1.6 3.4 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.8 0.6 7.7 0.6 0.6 0.0 15.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 3.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 49.2;Gastric mucus-secreting cells: 31.6;Paneth cells: 39.3;Proximal enterocytes: 36.2;Respiratory ciliated cells: 107.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 184.3;non-classical monocyte: 216.9" "Lineage enriched" "Detected in many" 7 "monocytes: 216.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: AB_2681346" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.97e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (3.71e-2)" "unprognostic (4.05e-2)" "unprognostic (6.53e-2)" "unprognostic (6.77e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-3)" "unprognostic (6.24e-2)" "unprognostic (3.85e-2)" "unprognostic (7.92e-3)" "unprognostic (2.46e-1)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" 5.2 5.1 2.9 14.5 2.9 4.5 3.1 3.9 3.8 9.2 12.6 70.1 91.9 3.3 1.4 2.1 19.3 18.7 1.2 3.1 2.7 29.1 15.0 5.1 3.9 2.8 2.7 1.7 7.0 0.9 3.5 5.4 2.9 6.2 64.7 4.3 2.2 4.4 3.4 4.8 76.0 7.3 2.4 5.9 15.6 3.3 3.0 4.5 1.6 0.7 4.0 3.5 2.3 3.3 3.4 11.6 7.9 4.8 1.6 1.7 5.7 2.2 2.3 4.8 3.0 22.1 29.8 3.7 3.0 1.9 3.7 15.1 18.2 2.8 2.0 3.3 16.9 6.7 21.6 7.9 3.5 5.8 14.7 1.6 4.4 1.8 3.4 3.0 5.9 10.8 6.2 3.9 0.7 10.2 14.5 12.6 8.5 24.1 3.4 30.1 8.1 8.2 1.3 6.0 4.4 4.3 3.5 3.2 9.9 3.1 2.8 12.6 3.5 5.0 4.5 9.2 8.7 14.4 9.4 10.0 3.3 14.9 2.2 0.1 43.7 0.2 0.1 184.3 0.6 0.6 0.6 0.2 29.1 0.1 0.5 0.3 21.3 0.0 216.9 1.4 0.4 18.3 2.9 2.9 3.9 3.8 3.1 2.7 2.8 2.7 2.9 2.4 3.0 3.3 1.3 0.0 1.5 3.3 0.7 1.5 0.8 2.8 1.8 11.1 0.4 0.1 0.3 12.8 15.8 3.7 0.0 0.5 0.3 49.2 0.0 2.5 6.5 9.4 0.6 6.4 7.7 1.3 3.8 4.3 0.5 3.2 31.6 0.4 0.0 0.4 5.0 8.1 3.9 8.4 4.0 17.1 0.0 11.7 1.5 0.5 3.7 8.1 0.0 4.7 3.9 2.0 2.1 3.0 3.4 3.0 39.3 6.8 2.4 1.1 36.2 25.4 107.8 3.1 0.0 1.1 0.7 0.0 0.4 1.3 2.0 0.1 1.2 0.1 21.1 1.1 CAMK2A "CAMKA, CaMKIIα, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 662.9" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 245.8" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Region enhanced" "Detected in many" "cerebral cortex: 662.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;SCLC-21H: 3.0;SuSa: 1.4;U-87 MG: 3.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 1071.1" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 66000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 0.2 0.9 161.7 0.2 230.9 0.1 0.1 0.0 662.9 1.2 0.0 1.0 0.1 2.8 0.3 1.3 1.5 0.3 4.8 453.1 0.0 0.7 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.0 3.5 0.3 0.0 0.8 0.2 1.9 0.7 0.4 95.0 0.7 0.4 2.4 0.0 0.3 0.5 0.1 0.0 0.0 0.1 34.7 0.0 2.0 0.7 99.6 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.8 0.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.9 0.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.7 230.9 0.0 662.9 453.1 0.0 0.0 0.0 0.0 0.0 0.0 99.6 0.0 0.0 0.0 12.1 0.0 3.4 0.0 0.0 0.0 5.1 0.0 0.0 14.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.2 0.0 0.0 245.8 0.0 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.0 55.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 3.6 9.4 0.0 0.4 0.0 8.5 8.1 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.1 0.0 3.6 1.8 0.0 0.3 0.0 1.4 0.3 0.2 0.0 0.0 0.0 CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIβ" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.8;skeletal muscle: 132.5" "Cell type enriched" "Detected in many" 7 "Bipolar cells: 857.4" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 0.5 11.3 77.9 0.6 109.0 0.1 1.4 113.0 248.8 0.1 0.0 1.0 1.0 0.2 28.3 1.4 1.1 0.2 65.4 197.6 12.6 1.6 7.7 0.3 1.3 4.4 11.9 0.3 3.8 6.1 51.3 0.1 4.6 3.2 0.4 21.4 1.4 1.6 132.5 1.2 0.9 0.1 3.2 0.3 2.3 2.1 25.9 0.8 20.3 59.2 1.6 0.0 0.3 80.4 0.0 0.8 0.4 0.6 0.0 0.4 0.4 0.3 0.1 0.3 0.0 0.3 0.1 0.2 1.6 0.4 0.1 0.3 0.4 1.4 0.1 2.0 4.5 0.1 0.2 0.2 0.1 0.0 0.9 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.1 10.1 0.0 0.4 0.2 0.1 4.4 0.2 1.7 0.3 0.0 0.0 75.5 4.0 0.4 0.0 0.0 0.1 3.5 0.3 0.4 0.5 0.7 0.4 0.1 0.9 0.8 0.2 0.2 0.0 0.5 1.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.4 0.7 0.3 0.2 0.2 0.2 77.9 109.0 113.0 248.8 197.6 12.6 4.4 11.9 4.6 3.2 25.9 80.4 0.1 0.0 0.0 67.3 0.2 1.1 21.5 0.0 10.8 857.4 3.1 17.5 88.9 2.8 0.0 0.0 45.9 0.1 0.0 0.5 9.8 0.0 0.9 2.3 0.4 1.6 40.7 0.0 111.4 0.0 0.2 2.9 4.1 5.6 4.5 15.4 0.0 4.3 0.2 60.6 90.9 1.5 2.0 0.6 0.4 2.9 1.8 0.5 1.8 5.6 0.0 23.2 0.0 19.6 5.4 0.1 1.2 0.0 0.1 3.3 0.1 1.9 0.0 53.1 0.0 6.9 1.7 0.2 7.8 0.9 0.4 0.3 0.2 0.2 0.3 6.6 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 159.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 272.9;Excitatory neurons: 182.9;Inhibitory neurons: 200.0;Microglial cells: 187.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 272.6" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 28.6 25.6 52.7 26.6 45.1 5.7 21.0 45.8 52.0 18.9 1.6 36.4 28.8 23.5 9.8 29.7 18.8 30.7 159.3 60.2 23.9 19.3 37.3 22.9 35.2 11.8 33.9 25.4 15.2 56.5 9.1 19.8 12.6 32.2 39.1 79.2 13.4 41.7 105.1 15.8 34.1 24.9 21.0 18.4 37.1 19.8 46.7 16.3 23.7 60.0 31.4 27.4 19.7 22.9 4.8 62.5 67.5 22.8 144.0 272.6 24.0 145.4 96.3 56.0 48.0 42.3 17.6 91.2 20.7 102.3 70.7 2.1 42.6 22.8 56.6 35.1 10.8 0.0 22.0 49.2 73.0 0.1 0.2 176.3 30.5 43.5 107.1 88.5 50.6 11.3 3.6 39.4 106.8 17.1 9.3 3.6 9.8 60.3 22.8 17.9 79.0 0.4 57.3 42.7 18.2 18.3 20.0 29.3 19.5 55.9 0.6 23.7 30.7 146.9 34.8 63.6 29.1 30.4 16.5 76.7 75.7 5.5 70.8 0.0 12.7 0.0 6.7 7.0 12.7 11.2 6.6 7.5 15.7 22.6 7.4 6.5 0.9 9.7 2.5 0.1 13.2 7.7 52.7 45.1 45.8 52.0 60.2 23.9 11.8 33.9 12.6 21.0 46.7 22.9 43.7 41.7 37.6 128.3 55.1 18.4 16.6 8.3 22.8 83.3 14.0 17.1 272.9 62.9 24.7 29.5 87.6 0.5 19.0 70.9 5.9 8.4 3.2 18.2 35.2 27.2 103.8 3.6 182.9 20.1 0.4 50.1 71.9 47.0 10.1 13.0 24.3 57.2 18.6 72.3 200.0 88.1 14.2 17.3 22.3 6.2 20.2 31.5 5.4 187.4 16.0 35.9 28.8 203.1 128.0 11.6 57.3 19.9 20.4 36.2 52.4 23.1 21.7 74.0 6.6 32.8 44.4 3.1 3.4 37.1 31.8 1.1 27.8 12.3 48.6 27.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.3" "Cell type enhanced" "Detected in many" "Astrocytes: 410.7;Cytotrophoblasts: 163.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 133.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 154.8;SK-BR-3: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 22.0 14.0 86.1 17.0 92.6 34.5 15.2 79.9 137.8 24.1 44.1 101.1 34.2 45.2 14.5 34.7 30.6 17.8 11.8 91.3 79.0 19.3 14.5 18.8 16.2 96.1 96.5 12.7 10.3 12.3 14.1 27.3 94.1 31.1 26.1 42.4 22.9 49.6 154.3 17.3 41.5 43.9 91.4 24.9 30.4 6.5 102.5 15.7 13.6 84.8 14.9 58.4 25.8 91.9 35.7 24.6 22.5 43.9 16.7 26.1 26.3 25.8 41.0 31.9 26.1 39.8 37.2 27.4 25.7 32.4 12.4 54.9 17.5 20.5 25.3 24.0 22.2 18.2 20.4 17.8 8.1 24.7 29.1 14.4 17.7 32.5 22.1 50.4 28.3 32.5 19.5 37.9 19.0 25.2 41.7 37.5 16.5 21.3 154.8 36.5 25.3 13.7 17.2 51.5 11.5 28.4 15.0 177.4 11.9 16.5 33.2 15.0 36.7 24.9 40.0 13.4 33.3 11.9 14.9 24.8 26.5 69.2 8.8 31.0 17.9 133.9 23.1 7.9 28.5 13.9 26.3 25.0 23.0 12.7 24.5 24.1 115.8 34.0 15.1 7.9 27.7 17.5 86.1 92.6 79.9 137.8 91.3 79.0 96.1 96.5 94.1 91.4 102.5 91.9 19.3 16.0 11.7 410.7 22.2 9.4 8.7 9.2 14.2 63.3 14.8 16.3 6.7 12.8 15.5 7.3 100.1 163.6 21.3 46.2 13.7 13.3 2.0 6.3 6.4 20.2 23.9 13.3 107.9 19.6 45.2 12.0 14.8 7.5 16.5 20.2 16.4 9.6 27.2 26.9 89.7 24.8 10.2 18.9 16.3 3.1 12.8 15.8 12.4 43.1 18.3 17.7 26.8 61.9 16.9 22.0 65.5 18.8 13.6 8.2 77.1 26.9 10.4 77.0 46.0 11.2 50.8 0.8 13.5 26.5 12.6 81.1 30.3 5.2 32.1 13.7 CAMLG "CAML, GET2" ENSG00000164615 "Calcium modulating ligand" P49069 5 134738495-134752157 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 845.6;Late spermatids: 1655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052636, HPA056472" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nucleoli" "HPA052636: AB_2681893, HPA056472: AB_2683143" "unprognostic (9.23e-2)" "unprognostic (8.54e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (3.07e-1)" "unprognostic (8.54e-2)" "unprognostic (5.34e-3)" "unprognostic (4.58e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (3.26e-2)" "unprognostic (1.43e-2)" "unprognostic (2.19e-1)" "unprognostic (3.16e-1)" 52.3 37.2 50.6 17.5 52.1 31.7 42.1 50.7 69.4 57.0 48.2 54.8 34.4 45.8 48.2 29.5 45.3 27.4 26.9 52.3 55.9 29.7 29.3 28.6 26.2 51.9 53.8 68.6 30.7 27.0 43.1 17.9 54.3 34.9 15.9 29.1 29.0 31.8 60.4 36.7 30.4 28.5 52.8 26.1 36.5 51.3 52.1 25.8 27.0 35.6 25.3 44.2 41.1 53.3 27.5 22.2 33.0 64.1 76.3 118.3 14.4 39.0 55.8 26.8 52.8 38.9 40.1 113.9 56.2 27.5 42.7 34.2 29.2 46.9 35.0 54.3 54.5 29.9 33.2 32.8 56.3 13.7 89.2 96.9 49.5 35.1 57.9 92.3 54.8 49.0 18.6 47.1 39.9 31.2 43.1 58.2 17.1 34.7 21.5 46.2 40.7 44.3 46.0 26.4 52.2 36.9 27.1 15.3 97.1 40.8 48.4 33.9 53.2 24.5 16.4 40.2 35.2 45.8 55.1 42.5 46.2 48.5 14.8 62.0 26.4 60.7 30.5 31.8 41.1 43.5 43.5 38.4 29.1 39.5 45.0 44.2 47.9 31.4 44.6 26.1 52.6 31.6 50.6 52.1 50.7 69.4 52.3 55.9 51.9 53.8 54.3 52.8 52.1 53.3 86.8 38.5 36.4 13.7 92.9 167.1 107.0 113.6 157.1 80.5 121.9 124.7 45.1 100.1 68.9 42.3 25.0 50.3 93.3 42.8 92.0 63.9 845.6 57.6 116.4 99.5 62.4 76.6 29.4 90.9 62.5 107.4 32.6 61.7 123.4 66.6 102.4 69.1 69.9 55.5 32.0 69.4 107.8 111.5 130.8 1655.8 168.0 76.6 96.0 10.3 126.9 127.7 90.6 15.1 18.6 67.5 58.0 132.4 55.2 148.6 158.2 199.1 51.3 71.4 98.6 119.5 109.7 241.5 68.6 119.3 201.6 73.2 101.6 67.9 90.9 107.9 CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: AB_2681362" "unprognostic (2.82e-1)" "unprognostic (3.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-3)" "unprognostic (1.10e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (2.78e-2)" "unprognostic (7.08e-2)" "prognostic favorable (6.00e-8)" "unprognostic (3.42e-2)" "unprognostic (9.02e-2)" "unprognostic (3.73e-2)" "unprognostic (1.20e-1)" "unprognostic (4.56e-2)" "unprognostic (1.19e-1)" 15.8 15.6 10.7 13.6 15.9 10.3 15.0 5.2 36.7 14.8 0.0 19.6 10.3 17.0 4.4 14.4 14.4 8.7 17.7 24.2 3.4 16.0 12.9 18.4 9.7 10.0 4.4 14.8 17.5 19.2 26.0 7.4 8.5 15.1 10.8 10.7 13.9 11.6 38.0 17.4 19.0 14.2 0.5 21.6 18.6 14.5 7.3 10.4 17.0 27.5 9.5 16.0 13.0 18.4 13.2 23.2 4.2 6.1 27.8 19.0 8.6 12.4 13.8 11.6 10.1 5.9 3.6 15.5 11.9 19.7 9.8 13.1 16.2 19.5 6.6 21.8 20.7 9.8 13.3 6.6 15.9 5.8 40.4 13.4 24.0 10.8 17.1 14.0 19.6 11.8 16.2 13.9 11.0 8.8 10.3 3.7 0.6 15.6 9.5 8.9 4.8 6.1 13.1 13.8 5.8 5.1 7.8 14.1 3.8 7.2 12.6 5.6 25.6 9.1 5.3 9.8 20.6 6.8 8.0 5.6 22.4 11.5 9.2 0.5 1.2 0.9 1.3 1.6 1.0 0.6 0.6 1.2 0.7 0.4 0.8 1.0 3.0 0.6 4.9 1.1 0.5 1.4 10.7 15.9 5.2 36.7 24.2 3.4 10.0 4.4 8.5 0.5 7.3 18.4 15.2 3.2 11.3 11.4 9.2 6.9 3.7 11.6 8.6 14.7 11.9 8.9 8.0 12.8 6.9 11.0 10.4 5.9 9.0 16.1 1.9 7.9 30.1 5.9 12.6 10.0 11.4 7.4 17.9 11.2 9.6 12.3 20.4 11.6 13.3 14.7 16.8 15.3 8.5 35.3 15.7 13.9 20.3 16.7 10.2 54.3 10.2 13.1 3.6 4.7 14.9 6.5 12.3 9.0 9.5 10.6 13.9 9.4 9.0 6.3 20.1 15.4 6.1 11.2 13.1 7.9 14.8 7.2 6.9 8.8 10.4 12.4 11.4 14.4 12.2 4.1 CAND1 "DKFZp434M1414, KIAA0829, TIP120, TIP120A" ENSG00000111530 "Cullin associated and neddylation dissociated 1" Q86VP6 12 67269358-67319953 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055748, HPA062833, HPA069053" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 5900000 "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA055748: AB_2682905, HPA062833: AB_2684876, HPA069053: AB_2686074" "unprognostic (1.50e-2)" "unprognostic (1.60e-1)" "unprognostic (1.39e-3)" "unprognostic (2.31e-1)" "unprognostic (2.19e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.02e-2)" "unprognostic (2.17e-2)" "unprognostic (3.02e-1)" "unprognostic (3.38e-3)" "unprognostic (1.66e-1)" "unprognostic (2.54e-2)" "unprognostic (2.88e-1)" "unprognostic (1.58e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" 18.4 23.1 19.6 19.9 21.4 22.6 25.9 25.3 21.8 21.4 15.9 19.8 19.5 21.2 27.8 22.5 19.2 18.3 12.6 20.9 21.7 24.3 27.4 16.8 27.5 18.8 19.0 25.0 18.7 28.3 19.3 23.2 21.2 22.4 20.6 37.5 16.5 20.0 9.9 29.3 18.5 21.6 19.5 19.1 18.2 27.8 19.5 38.8 26.0 11.4 30.8 23.3 19.3 19.5 62.1 62.6 93.1 66.6 69.7 54.3 62.4 60.2 51.6 62.0 54.2 58.4 34.5 132.9 51.0 60.6 38.9 57.8 101.1 68.3 70.6 50.8 60.5 75.1 46.5 55.7 45.7 89.5 40.9 51.5 51.0 56.8 51.9 75.8 58.7 63.9 60.4 72.3 67.7 61.0 81.6 60.3 98.8 47.4 43.1 78.4 79.8 56.3 57.3 103.9 95.2 47.3 74.9 68.0 49.9 77.8 73.2 40.7 50.3 49.0 31.5 34.1 46.1 23.5 31.1 111.5 58.3 52.2 51.4 9.3 6.4 7.4 14.0 7.4 17.0 10.9 16.8 15.3 10.0 14.7 17.7 14.9 2.7 19.0 14.0 8.6 19.3 5.7 19.6 21.4 25.3 21.8 20.9 21.7 18.8 19.0 21.2 19.5 19.5 19.5 37.6 60.9 36.3 38.5 61.2 58.1 50.2 51.6 57.5 92.4 51.4 40.6 17.0 42.9 42.0 44.1 116.7 37.4 61.5 47.3 13.7 30.7 3.9 45.2 53.9 44.6 45.4 34.9 48.8 28.6 42.7 47.7 41.3 51.1 7.6 71.0 40.4 49.8 31.3 87.5 61.7 50.4 34.6 42.4 52.4 11.0 69.0 35.9 33.8 32.8 54.6 53.8 48.4 49.8 63.5 35.2 28.6 60.9 55.1 56.6 59.8 32.3 55.3 115.3 26.3 52.1 50.7 82.5 47.7 47.1 63.9 44.6 59.3 66.4 46.5 64.2 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CAPN6 "CalpM, CANPX, CAPNX" ENSG00000077274 "Calpain 6" Q9Y6Q1 X 111245099-111270483 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 212.7;placenta: 83.1;seminal vesicle: 72.4" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 198.5;Syncytiotrophoblasts: 140.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 25.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 10.8;NTERA-2: 16.3;SuSa: 14.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.6" HPA040259 Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA040259: " "unprognostic (1.27e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-2)" "unprognostic (5.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.93e-2)" "unprognostic (8.39e-3)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-3)" "unprognostic (5.12e-1)" "unprognostic (6.25e-2)" "unprognostic (7.67e-2)" "unprognostic (6.50e-2)" "unprognostic (5.02e-3)" "unprognostic (2.66e-1)" "unprognostic (6.30e-2)" 2.1 0.0 0.0 7.2 0.0 0.0 12.7 0.0 0.0 11.9 0.0 5.6 1.8 22.5 212.7 2.3 3.2 8.4 0.3 0.0 0.0 11.5 0.3 0.5 2.8 0.0 0.0 2.6 7.5 0.1 0.2 83.1 0.0 10.6 8.6 0.0 14.1 72.4 3.0 1.0 1.7 8.2 0.0 1.7 12.9 2.0 0.0 1.8 1.5 9.0 4.7 3.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 16.3 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.1 0.3 0.4 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.6 2.0 0.3 7.2 0.0 7.3 0.0 39.9 0.1 0.1 3.9 8.3 0.0 18.0 4.3 0.4 0.0 0.0 0.0 0.7 198.5 12.9 6.6 40.1 0.0 0.0 0.0 0.0 7.6 0.0 0.1 1.2 0.0 0.0 0.3 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 22.2 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.0 0.5 0.1 0.1 0.9 0.0 140.5 0.3 0.9 0.5 0.3 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 291.1" "Cell type enriched" "Detected in many" 6 "Gastric mucus-secreting cells: 910.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 125.9;RT4: 76.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.3 0.2 4.7 6.3 1.0 0.1 14.9 0.1 1.7 1.1 2.3 23.6 8.0 0.1 11.1 0.6 1.3 14.3 0.0 2.3 3.6 1.7 0.3 21.3 0.1 2.7 1.5 0.2 2.9 0.0 0.1 0.3 1.1 2.9 33.0 0.3 8.5 1.4 0.8 2.3 4.6 1.1 2.0 0.3 291.1 0.6 1.8 0.0 0.2 0.0 0.3 12.3 0.7 2.5 1.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.8 0.0 4.6 0.0 0.1 0.0 0.2 8.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.2 125.9 3.8 0.1 0.0 0.0 1.3 76.8 1.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 4.7 1.0 0.1 1.7 2.3 3.6 2.7 1.5 1.1 2.0 1.8 2.5 0.4 28.9 131.7 1.6 1.8 0.1 6.5 1.9 0.0 0.0 19.9 7.9 2.6 10.0 55.9 25.8 0.0 0.2 0.2 90.9 0.0 3.8 2.3 2.0 0.3 0.7 3.0 0.0 0.6 21.6 0.0 0.3 910.8 2.1 10.8 5.2 0.0 0.3 0.6 0.0 0.1 61.9 4.1 0.0 0.8 6.7 1.8 1.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 36.1 42.6 3.4 3.5 4.0 2.1 1.5 15.0 0.0 0.0 0.3 0.8 0.4 1.0 0.0 0.0 0.1 1.4 2.9 21.2 31.2 CAPRIN2 "C1QDC1, caprin-2, EEG1, FLJ11391, FLJ22569, RNG140" ENSG00000110888 "Caprin family member 2" Q6IMN6 12 30709552-30754951 "Predicted intracellular proteins" "Differentiation, Growth regulation" "Protein synthesis inhibitor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 73.8;Inhibitory neurons: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039746 Supported Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoplasm, Centrosome" "HPA039746: AB_10672902" "unprognostic (7.45e-2)" "unprognostic (6.38e-2)" "unprognostic (2.83e-3)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-2)" "unprognostic (1.92e-1)" "unprognostic (8.91e-2)" "unprognostic (9.90e-2)" "unprognostic (3.09e-1)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.50e-5)" "unprognostic (1.91e-1)" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "prognostic favorable (8.36e-4)" 4.2 6.1 11.7 4.0 12.1 8.5 3.7 11.3 20.3 5.7 3.2 6.3 2.8 6.3 7.4 2.9 5.1 4.4 13.5 10.7 37.4 5.7 5.6 4.7 4.3 20.5 8.8 7.3 5.8 9.4 10.0 3.0 16.3 5.6 4.0 18.0 3.2 6.9 6.0 8.0 4.9 6.1 3.8 6.1 5.5 17.4 12.7 3.6 5.0 5.0 3.6 6.0 4.3 12.1 7.4 5.1 9.4 7.9 9.1 9.5 5.7 13.4 11.2 5.7 7.7 2.8 4.6 4.3 11.5 14.1 11.3 5.8 5.0 22.0 10.3 6.5 5.6 18.0 9.5 10.4 5.1 2.9 1.8 11.1 8.4 18.2 14.6 23.6 13.0 7.7 1.1 4.3 13.6 1.4 3.7 4.6 11.0 3.9 15.2 1.6 14.1 2.1 2.5 26.1 11.7 7.1 5.0 3.6 5.6 22.3 3.2 0.9 17.8 11.0 6.0 33.5 24.9 8.1 6.1 4.1 13.2 0.9 7.3 6.2 0.8 0.7 2.4 0.3 2.9 2.6 1.5 2.6 0.4 2.1 1.7 1.6 0.1 1.7 0.4 2.4 1.1 0.6 11.7 12.1 11.3 20.3 10.7 37.4 20.5 8.8 16.3 3.8 12.7 12.1 9.8 22.4 27.7 45.1 9.0 7.1 4.9 3.8 7.4 28.9 6.4 9.1 28.7 0.0 6.3 3.7 22.9 8.6 14.7 5.3 9.8 5.6 17.2 21.8 12.2 11.6 16.7 23.5 73.8 11.2 1.7 12.2 11.2 10.0 22.1 19.6 7.9 8.0 9.6 11.8 68.5 5.0 0.0 7.8 4.4 13.7 6.8 6.7 3.6 12.2 4.5 10.5 11.3 49.3 19.4 33.9 2.2 8.6 8.8 2.5 4.5 11.9 13.0 34.2 6.6 13.2 11.3 8.2 33.5 9.2 4.5 12.3 11.8 9.8 3.9 3.3 CAPS "CAPS1, MGC126562" ENSG00000105519 Calcyphosine Q13938 19 5912339-5916211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 334.8" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2622.9;Respiratory ciliated cells: 1557.4" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 171.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 19.4;SK-BR-3: 65.1;U-266/70: 19.8" "Low region specificity" "Detected in all" HPA043520 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA043520: AB_10964138" "unprognostic (2.06e-1)" "unprognostic (1.13e-2)" "unprognostic (7.94e-3)" "prognostic favorable (7.63e-5)" "unprognostic (5.18e-1)" "prognostic favorable (8.60e-4)" "unprognostic (7.07e-2)" "unprognostic (2.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (9.99e-2)" "unprognostic (4.01e-2)" "unprognostic (8.47e-2)" "unprognostic (3.25e-1)" "unprognostic (6.86e-3)" "unprognostic (5.96e-3)" 12.2 25.9 37.5 10.9 35.1 10.0 11.6 55.0 30.1 47.2 55.4 16.1 6.9 21.7 4.6 12.9 334.8 11.2 13.5 40.2 69.6 38.3 21.5 49.5 12.2 72.6 105.3 13.8 24.0 3.3 27.9 9.3 85.7 40.4 2.8 2.2 24.9 30.9 4.3 16.2 18.7 2.3 60.9 25.2 37.5 6.4 50.0 5.7 30.8 1.1 4.2 44.2 13.7 66.1 2.2 2.3 0.9 6.3 2.1 3.2 4.0 0.7 0.7 0.3 0.6 1.5 13.8 0.9 4.0 1.5 0.7 2.3 0.1 0.6 0.0 4.7 1.9 0.8 4.8 4.7 2.5 0.8 3.5 4.1 4.2 0.4 0.8 4.0 1.0 4.7 0.7 5.4 0.7 4.4 2.4 4.0 0.7 19.4 12.6 3.1 0.3 4.7 1.8 6.2 1.0 4.9 1.0 65.1 6.6 2.0 4.3 4.7 1.5 0.6 0.4 4.6 17.1 19.8 6.5 1.1 7.7 1.8 2.8 0.4 0.7 0.3 1.7 0.6 0.9 0.9 1.0 1.3 0.8 1.8 0.8 0.7 0.7 1.8 0.4 1.5 1.0 0.8 37.5 35.1 55.0 30.1 40.2 69.6 72.6 105.3 85.7 60.9 50.0 66.1 5.3 12.8 16.5 11.1 3.3 4.8 32.1 122.8 1.8 2.5 8.9 8.8 2.2 0.0 161.5 121.4 4.2 24.3 7.4 5.3 35.2 34.7 6.5 2622.9 48.3 5.5 19.2 0.4 2.6 5.9 22.8 12.9 33.6 330.8 6.3 8.1 0.0 0.0 5.2 6.7 3.2 25.1 197.4 0.0 5.9 5.7 4.7 6.6 10.6 6.5 3.0 7.7 9.2 3.5 12.9 36.9 3.3 4.9 3.8 20.4 4.2 4.5 1557.4 4.2 6.6 3.5 42.7 0.4 0.6 0.9 4.1 20.5 9.2 3.3 9.3 128.6 CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 133.8;Inhibitory neurons: 95.8;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 102.6;Respiratory ciliated cells: 77.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: AB_10794758" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (7.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.36e-1)" "unprognostic (9.61e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-3)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.52e-2)" "unprognostic (2.69e-1)" 1.0 1.5 1.2 0.3 1.2 0.5 1.4 1.7 4.0 1.2 8.8 1.0 0.6 2.0 3.7 1.3 10.0 1.3 2.3 1.1 3.1 2.7 1.8 2.4 0.3 5.5 4.3 1.6 0.9 3.9 2.5 0.1 2.5 2.0 0.6 11.8 2.4 1.3 1.7 0.9 0.6 0.6 2.7 1.0 1.3 3.8 2.3 0.6 4.0 3.2 0.3 0.7 0.7 2.6 0.7 2.1 0.6 0.1 1.0 0.7 0.0 0.4 0.1 1.1 1.2 0.0 1.0 0.2 1.8 0.3 0.4 0.5 0.0 1.0 0.8 0.7 0.3 0.9 0.4 0.0 0.0 0.1 0.0 0.3 0.5 0.9 0.2 6.8 0.1 0.7 0.2 0.3 1.5 0.0 1.0 0.8 0.3 0.0 0.3 0.0 0.0 0.1 1.5 0.0 1.2 0.6 0.1 0.0 0.6 0.1 0.7 0.3 0.5 1.0 0.5 0.2 0.1 0.1 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.0 1.2 1.2 1.7 4.0 1.1 3.1 5.5 4.3 2.5 2.7 2.3 2.6 3.3 9.6 2.8 85.5 1.7 1.8 2.6 2.9 7.4 1.5 3.1 3.0 8.2 1.5 11.5 5.5 4.2 1.2 0.9 0.4 5.9 1.1 35.8 24.3 2.1 2.3 0.0 4.6 133.8 1.7 0.6 4.8 4.6 0.9 0.0 6.0 3.3 2.4 0.5 1.7 95.8 1.3 2.0 1.6 1.7 14.9 6.2 1.3 0.0 46.9 0.1 6.7 2.1 117.1 102.6 0.6 0.3 7.2 2.5 1.0 0.5 3.5 77.2 22.4 0.0 3.8 3.8 8.5 1.6 4.1 0.6 0.3 1.6 3.3 0.8 0.6 CAPZB ENSG00000077549 "Capping actin protein of muscle Z-line subunit beta" P47756 1 19338775-19485539 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1188.8;Late spermatids: 3669.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031531 Approved Approved Nucleoplasm,Vesicles,Cytosol No No 6600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Vesicles "HPA031531: AB_10603556" "unprognostic (7.52e-2)" "unprognostic (2.13e-1)" "unprognostic (5.25e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (1.85e-4)" "unprognostic (4.55e-2)" "unprognostic (7.70e-2)" "unprognostic (3.08e-1)" "unprognostic (4.15e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.57e-4)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (4.00e-1)" "unprognostic (3.78e-1)" 210.2 193.0 126.1 196.7 126.9 154.3 189.1 128.8 133.4 233.9 129.0 294.5 149.1 254.5 145.8 265.1 199.9 144.2 207.5 139.9 129.8 161.3 127.7 217.9 223.8 133.7 128.6 205.1 94.2 128.6 121.5 178.7 132.5 200.9 214.2 123.8 152.5 177.9 301.8 195.1 220.6 241.4 126.3 215.9 192.6 216.2 135.8 237.1 155.2 214.2 271.8 230.3 222.2 143.8 263.9 146.4 260.0 179.3 355.6 467.0 187.9 435.9 430.0 364.0 377.5 189.6 338.1 179.7 186.4 533.5 218.7 212.0 224.0 297.9 424.3 280.0 160.5 340.1 170.6 298.3 355.0 236.5 533.6 424.0 243.4 314.9 292.6 300.5 338.6 204.5 132.1 229.7 393.9 185.1 270.5 307.0 200.5 343.8 155.3 223.4 184.6 225.2 507.6 133.0 158.0 123.4 255.2 200.6 299.3 229.5 222.2 199.6 351.5 237.9 207.0 409.4 208.7 156.0 188.8 217.4 314.1 306.8 261.5 456.1 358.2 1077.5 304.0 542.3 265.0 266.1 318.5 329.4 362.3 203.7 263.5 293.7 576.3 196.7 703.0 199.1 404.2 597.6 126.1 126.9 128.8 133.4 139.9 129.8 133.7 128.6 132.5 126.3 135.8 143.8 197.7 99.3 68.9 52.9 160.3 156.3 282.8 263.0 103.6 93.9 106.9 117.7 87.6 112.9 143.5 101.2 41.7 338.0 247.5 301.7 297.4 322.1 1188.8 86.7 122.2 182.4 141.2 89.4 49.8 256.5 396.4 178.9 101.9 96.8 147.5 164.6 156.0 98.7 800.9 77.4 67.5 278.7 215.7 302.6 276.7 3669.8 232.7 311.2 144.1 124.6 561.5 151.1 338.8 42.7 64.9 349.6 295.2 302.4 103.4 206.8 235.6 251.2 122.6 93.2 243.3 97.8 262.6 119.0 81.5 150.3 182.7 342.2 268.2 197.9 193.8 280.5 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CARF "ALS2CR8, FLJ21579, NYD-SP24" ENSG00000138380 "Calcium responsive transcription factor" Q8N187 2 202912214-202988263 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034557, HPA043191" Approved Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoli fibrillar center, Cytosol" "HPA034557: AB_10601663, HPA043191: AB_2732503" "unprognostic (4.63e-2)" "unprognostic (3.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.93e-2)" "unprognostic (6.09e-2)" "unprognostic (8.65e-3)" "unprognostic (1.12e-1)" "unprognostic (2.13e-3)" "unprognostic (4.39e-2)" "unprognostic (1.10e-1)" "unprognostic (7.58e-3)" "unprognostic (1.08e-1)" "unprognostic (6.12e-2)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" 4.5 5.3 4.2 5.7 8.6 5.4 7.7 6.4 5.1 5.9 2.5 5.2 4.5 9.4 9.9 5.5 6.8 6.0 4.9 4.4 5.0 6.8 4.5 5.1 8.8 5.9 6.0 7.9 3.9 7.8 5.1 4.7 6.5 6.7 6.0 16.1 4.6 6.4 4.5 7.4 4.9 6.6 4.6 7.5 6.0 21.5 5.5 9.4 10.6 5.4 7.8 5.7 5.0 12.3 2.5 2.4 6.1 5.4 4.5 9.5 4.7 3.7 4.7 3.8 3.4 2.8 6.2 3.8 1.6 4.3 4.6 4.5 3.2 2.7 4.3 3.0 1.7 5.9 3.0 1.7 3.8 3.5 2.9 7.8 5.2 3.3 8.6 9.6 2.3 13.9 2.5 15.5 5.9 4.9 7.2 5.6 2.6 1.6 3.5 5.1 4.2 3.1 6.9 2.6 4.3 4.6 4.0 2.2 1.7 7.7 3.6 6.5 2.7 7.1 1.8 4.6 2.4 13.7 8.4 4.2 6.1 4.1 4.4 1.4 1.0 0.8 2.2 1.9 2.4 2.0 2.2 2.1 1.2 2.4 3.1 2.2 0.4 8.8 1.1 1.9 4.7 0.6 4.2 8.6 6.4 5.1 4.4 5.0 5.9 6.0 6.5 4.6 5.5 12.3 5.6 9.6 15.7 28.7 14.6 3.2 3.9 5.5 5.2 33.5 6.7 5.5 6.6 7.2 14.1 14.7 18.8 4.2 9.2 2.7 11.7 4.4 19.0 7.1 5.0 5.6 1.8 7.6 21.5 2.4 9.3 7.4 5.6 2.9 20.3 19.6 8.2 3.2 3.9 26.9 25.0 4.7 6.1 8.2 3.7 16.7 10.8 4.9 1.8 16.9 5.9 9.6 18.6 39.2 66.1 2.9 3.2 9.4 4.0 2.0 9.5 5.8 17.7 31.1 6.6 7.1 5.6 37.2 8.6 4.4 2.7 1.8 10.2 10.5 6.2 2.7 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 858.4;Early spermatids: 979.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882, HPA075906" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 17000000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "CAB009491: AB_2259755, HPA036881: AB_2675359, HPA036882: AB_2675360, HPA075906: " "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (3.79e-1)" "unprognostic (4.53e-3)" "unprognostic (1.94e-2)" "unprognostic (6.11e-3)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.66e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (4.98e-4)" 144.4 68.4 32.3 86.1 36.3 119.1 104.1 35.0 40.8 147.2 55.5 160.1 120.5 83.8 49.0 342.8 79.7 78.7 303.7 30.7 42.2 82.0 116.8 112.1 52.9 46.7 43.2 83.1 56.1 111.7 51.2 116.1 44.4 100.2 148.2 17.1 130.0 78.7 317.3 157.4 137.2 92.2 38.3 64.1 100.5 98.8 39.1 43.1 97.9 166.4 104.3 129.4 216.4 41.7 300.3 239.7 42.6 112.1 240.1 390.1 145.4 220.9 288.8 169.1 215.8 60.4 189.6 44.1 189.8 286.1 263.1 465.6 81.3 283.5 202.8 292.4 78.5 65.9 251.0 71.1 172.9 38.9 100.1 201.8 254.8 239.6 375.0 222.9 194.8 33.5 51.7 144.5 196.4 98.0 17.9 2.0 35.4 85.0 89.9 18.2 141.9 78.3 327.1 114.1 179.6 45.0 222.6 118.2 142.5 94.0 77.4 39.5 263.9 239.0 94.6 154.9 211.4 51.2 140.4 22.1 264.7 21.8 67.5 10.5 156.6 24.1 75.6 85.3 74.1 79.4 68.2 76.9 107.5 79.1 34.8 45.7 38.2 61.6 109.8 28.8 79.2 108.1 32.3 36.3 35.0 40.8 30.7 42.2 46.7 43.2 44.4 38.3 39.1 41.7 251.6 403.8 221.4 58.1 153.8 239.6 439.8 223.6 169.0 39.4 133.6 84.5 858.4 163.0 277.0 108.5 18.8 181.2 227.1 484.0 133.1 263.6 979.7 348.0 213.4 188.5 142.1 229.3 60.2 249.7 96.2 259.0 153.4 327.8 177.1 71.8 138.8 169.3 113.7 13.5 53.0 253.9 103.7 209.4 259.1 414.4 172.1 243.8 131.6 63.7 354.4 36.9 293.6 33.2 70.2 325.1 346.8 146.3 126.3 314.7 302.9 152.3 379.0 19.5 92.1 267.8 175.0 23.6 17.9 348.9 251.7 140.8 207.7 69.8 221.2 548.5 CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 31.3" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Gastric mucus-secreting cells: 27.0;Late spermatids: 49.2;Proximal enterocytes: 20.7;Spermatocytes: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 1.4;HMC-1: 1.8;MCF7: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in male reproductive system" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Cytosol" "HPA052777: " "unprognostic (8.50e-5)" "unprognostic (5.12e-2)" "unprognostic (3.57e-3)" "unprognostic (1.51e-1)" "unprognostic (2.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.60e-1)" "unprognostic (2.87e-3)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (1.07e-3)" 0.2 0.1 0.5 0.1 0.8 0.3 0.4 0.8 0.9 0.4 0.2 0.2 0.4 0.2 0.7 0.2 0.5 0.1 0.1 0.4 0.5 0.2 0.2 0.3 0.3 0.7 2.8 0.4 0.2 0.2 0.2 0.1 0.7 0.4 0.2 0.2 0.3 0.2 0.2 1.0 0.3 0.1 0.4 0.2 0.2 31.3 0.8 0.2 0.5 0.0 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.6 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.3 0.0 0.1 0.2 0.0 0.3 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.7 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.5 0.0 0.7 0.1 0.1 0.0 0.5 0.8 0.8 0.9 0.4 0.5 0.7 2.8 0.7 0.4 0.8 1.1 4.9 0.0 2.7 2.6 3.6 2.5 2.4 1.0 4.6 1.3 4.8 8.0 3.0 1.5 0.6 1.8 0.0 1.7 5.1 10.1 0.0 1.0 29.4 4.9 4.4 2.7 1.8 3.2 4.3 0.7 0.3 3.0 27.0 8.8 1.3 2.0 2.5 0.3 3.2 1.7 3.8 3.9 2.0 1.2 3.1 49.2 1.8 3.3 0.0 1.9 3.9 1.9 10.3 3.0 17.0 0.4 5.6 2.2 2.2 1.9 20.7 0.9 1.3 1.4 0.0 5.3 3.7 28.9 3.7 4.9 1.8 1.4 3.4 1.9 3.5 1.8 CAVIN4 "cavin-4, MURC" ENSG00000170681 "Caveolae associated protein 4" Q5BKX8 9 100578079-100588389 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 276.1;tongue: 92.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.5;Endometrial ciliated cells: 1.2;Endometrial stromal cells: 1.8;Glandular and luminal cells: 1.9;Granulosa cells: 1.8;Pancreatic endocrine cells: 1.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.9;SCLC-21H: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020973, HPA020987, HPA021021" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA020973: AB_1853079, HPA020987: AB_1853080, HPA021021: AB_1853082" "unprognostic (9.54e-5)" "unprognostic (1.68e-2)" "unprognostic (2.50e-2)" "unprognostic (3.76e-2)" "unprognostic (4.92e-2)" "unprognostic (4.56e-3)" "unprognostic (1.14e-4)" "unprognostic (3.36e-2)" "unprognostic (2.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (4.02e-1)" "unprognostic (1.74e-8)" "unprognostic (1.14e-1)" "unprognostic (3.39e-1)" "unprognostic (3.68e-3)" "unprognostic (1.55e-3)" 0.2 0.1 1.6 0.2 2.9 0.1 0.1 2.0 5.6 0.4 0.4 0.4 0.0 0.5 0.1 4.3 0.1 0.3 45.9 1.7 2.5 0.2 0.2 0.4 0.1 2.7 2.7 0.2 0.1 0.0 0.2 0.3 2.7 4.5 0.1 0.3 2.4 0.1 276.1 0.2 0.1 0.3 1.8 0.1 0.3 3.7 2.7 0.4 0.5 92.4 0.1 0.3 0.2 3.5 0.5 0.3 6.1 2.2 1.4 2.0 4.3 1.1 0.9 0.8 1.0 0.0 0.4 0.2 0.3 0.6 2.1 0.3 3.1 0.1 1.7 1.4 2.0 0.1 1.0 0.0 0.4 0.2 0.4 5.0 0.3 0.8 0.5 1.5 1.1 1.5 0.2 0.2 3.9 0.1 1.8 0.3 8.9 1.0 0.7 2.6 5.8 0.0 0.8 0.3 13.2 3.4 0.2 0.2 1.1 4.1 0.1 0.2 1.1 1.5 1.2 1.0 1.0 0.3 1.1 0.6 1.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.9 2.0 5.6 1.7 2.5 2.7 2.7 2.7 1.8 2.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.7 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.9 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 CC2D1A "FLJ20241, Freud-1, MRT3" ENSG00000132024 "Coiled-coil and C2 domain containing 1A" Q6P1N0 19 13906201-13930879 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005436, CAB015220" Supported Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli fibrillar center" "CAB015220: , HPA005436: AB_1078884" "unprognostic (8.66e-2)" "unprognostic (1.31e-2)" "unprognostic (2.55e-1)" "unprognostic (2.34e-1)" "unprognostic (1.07e-1)" "prognostic favorable (7.02e-4)" "unprognostic (7.00e-2)" "unprognostic (1.59e-3)" "unprognostic (1.17e-1)" "unprognostic (2.82e-2)" "unprognostic (2.61e-3)" "unprognostic (4.07e-2)" "unprognostic (1.23e-3)" "unprognostic (6.67e-3)" "unprognostic (1.97e-1)" "unprognostic (9.22e-2)" "unprognostic (1.71e-2)" 16.8 16.4 11.6 3.8 11.3 3.7 21.3 10.1 18.1 19.4 10.3 37.4 16.2 16.2 2.1 33.3 19.8 2.9 20.5 11.8 11.9 22.9 26.9 16.0 3.2 11.3 11.4 18.7 34.3 7.9 31.8 3.1 11.8 25.8 4.7 4.1 27.4 5.2 28.3 35.5 33.1 3.4 9.8 17.7 24.7 15.9 13.2 2.6 20.6 3.9 3.1 21.2 24.8 10.8 22.0 8.5 2.3 9.9 5.1 3.1 9.3 6.9 8.1 10.2 10.4 14.5 6.8 11.2 11.4 6.1 6.4 15.2 5.3 10.1 3.3 17.0 30.9 5.2 11.0 6.9 9.0 4.1 15.2 4.7 12.5 7.2 4.3 6.5 7.2 11.5 6.4 8.5 3.4 22.4 11.6 12.1 7.1 18.5 16.7 11.2 6.3 8.9 6.5 16.3 10.2 7.1 9.8 13.3 12.2 1.6 10.4 9.8 6.3 8.3 4.4 20.9 8.9 15.2 7.3 6.6 10.8 14.3 7.8 0.5 0.3 0.8 0.4 0.7 0.1 0.2 0.2 0.2 0.4 0.1 0.0 0.2 0.1 0.2 0.5 0.3 0.3 0.3 11.6 11.3 10.1 18.1 11.8 11.9 11.3 11.4 11.8 9.8 13.2 10.8 20.6 9.6 8.3 23.8 12.6 9.1 14.2 15.6 19.4 66.6 19.2 64.6 8.4 21.5 16.5 11.0 93.8 22.3 11.7 103.4 9.8 22.0 2.2 10.1 6.7 13.2 33.5 18.7 38.4 27.7 10.7 10.5 63.7 11.3 17.7 29.3 12.8 12.4 14.5 30.3 43.3 46.6 24.4 12.2 13.0 6.5 64.3 11.3 7.2 10.3 16.3 15.6 23.7 31.2 24.1 26.0 77.6 87.3 12.3 13.0 97.9 6.8 16.7 93.2 13.1 8.0 9.3 10.2 12.4 24.8 13.8 21.3 14.8 16.1 64.3 18.8 CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: AB_10669751, HPA050442: AB_2681128" "unprognostic (3.70e-3)" "unprognostic (7.07e-3)" "unprognostic (3.60e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.09e-2)" "unprognostic (4.13e-1)" "unprognostic (1.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" 91.6 61.0 35.1 19.1 34.6 7.8 75.3 37.4 40.6 48.5 36.0 117.8 19.2 74.2 31.1 25.1 60.6 15.3 90.3 34.5 35.3 37.7 50.3 43.6 15.4 35.5 35.7 32.3 62.7 12.8 33.0 13.9 36.0 55.9 16.8 13.9 26.6 29.2 64.4 32.5 47.1 28.2 34.7 41.2 74.4 17.1 37.3 26.0 31.4 22.4 14.4 76.6 39.1 35.0 17.9 15.7 12.8 16.3 63.3 40.3 7.4 29.5 26.4 18.5 17.2 7.2 5.2 11.5 12.8 38.9 47.6 5.9 9.6 14.2 13.6 34.4 15.3 5.5 25.1 18.3 15.0 8.5 20.1 24.1 16.6 19.8 15.3 34.4 13.1 19.2 7.2 21.7 23.4 11.6 9.5 12.6 9.5 12.6 48.2 13.7 2.9 9.3 62.8 9.6 8.4 14.0 15.2 21.1 15.4 9.5 11.1 10.4 16.7 29.5 16.3 21.6 27.3 9.6 15.4 23.1 54.6 13.5 26.2 33.3 39.3 20.1 128.7 43.2 168.8 79.5 111.6 113.8 45.0 79.5 53.2 74.2 7.8 69.3 25.9 123.8 140.8 75.1 35.1 34.6 37.4 40.6 34.5 35.3 35.5 35.7 36.0 34.7 37.3 35.0 68.7 67.3 25.0 11.1 104.8 70.2 38.0 76.9 8.6 31.9 39.2 65.3 0.7 60.1 48.4 82.8 8.4 15.0 175.2 143.9 17.6 74.1 7.6 33.5 34.1 36.1 88.1 15.8 8.6 140.2 66.2 60.0 121.8 30.5 34.3 24.4 53.9 77.3 90.9 32.0 10.2 100.5 69.2 46.9 185.9 28.3 59.4 82.0 113.8 13.1 43.5 57.2 133.9 7.5 10.8 86.7 108.6 102.3 53.3 45.3 146.7 66.9 48.2 34.1 118.3 33.7 135.3 37.9 63.1 17.8 66.9 13.8 132.7 44.9 51.7 29.5 CCDC112 MGC39633 ENSG00000164221 "Coiled-coil domain containing 112" Q8NEF3 5 115267190-115296693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045120, HPA050621" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA045120: AB_2679222, HPA050621: AB_2681191" "unprognostic (1.88e-2)" "unprognostic (5.10e-2)" "unprognostic (4.63e-2)" "unprognostic (5.60e-3)" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.32e-6)" "unprognostic (4.30e-2)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (3.33e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (1.51e-6)" "unprognostic (7.00e-2)" "unprognostic (2.79e-2)" "unprognostic (8.61e-2)" "unprognostic (4.10e-3)" 4.3 3.6 5.7 5.3 6.3 7.3 6.0 7.4 7.3 4.5 2.6 9.1 7.2 5.6 6.2 4.5 4.1 3.1 6.0 5.8 6.6 2.8 1.2 5.5 4.6 6.4 5.5 2.1 10.2 4.5 4.6 2.4 6.3 6.7 9.3 7.9 6.5 5.0 4.3 4.9 6.3 5.4 5.7 4.6 6.4 40.7 5.9 3.7 4.0 2.5 4.2 3.8 3.6 7.8 12.0 5.9 11.5 18.5 7.1 14.0 2.9 10.5 5.3 7.7 8.7 2.6 6.7 14.8 8.9 7.2 11.4 7.5 12.1 6.0 16.0 12.0 10.1 9.8 8.8 3.8 9.7 12.9 4.8 6.4 7.2 9.8 13.0 8.8 12.1 13.1 4.1 11.6 10.8 9.3 19.2 11.4 13.1 11.0 11.0 20.6 14.5 113.7 7.7 4.2 17.9 23.5 11.5 7.2 32.8 7.8 12.2 18.9 12.6 10.1 6.9 19.7 14.8 13.2 13.2 3.0 6.7 9.9 6.0 0.3 5.0 11.0 2.9 4.0 3.3 2.8 2.2 2.5 5.4 4.0 2.8 1.9 3.2 3.0 4.9 10.2 0.1 2.1 5.7 6.3 7.4 7.3 5.8 6.6 6.4 5.5 6.3 5.7 5.9 7.8 15.7 16.0 14.0 16.0 19.2 14.1 5.0 6.0 8.0 29.2 19.4 18.4 17.6 8.6 8.4 5.5 10.4 0.7 19.5 23.6 5.9 28.2 8.5 23.0 21.4 12.4 40.6 20.8 26.4 25.9 2.0 11.5 14.3 12.3 9.5 15.0 7.9 3.1 32.7 10.1 15.2 33.4 6.1 28.6 31.5 18.5 4.1 31.5 14.2 15.0 36.6 11.0 11.3 21.1 54.7 27.1 18.7 4.1 27.3 8.0 11.8 4.4 11.7 24.9 13.1 18.5 18.2 201.8 73.3 13.8 22.6 0.5 9.2 5.5 32.8 3.4 CCDC117 FLJ33814 ENSG00000159873 "Coiled-coil domain containing 117" Q8IWD4 22 28772674-28789301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 104.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000826 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Microtubules, Cytosol" "HPA000826: AB_1078417" "unprognostic (1.71e-1)" "unprognostic (2.04e-2)" "unprognostic (1.61e-3)" "unprognostic (9.07e-2)" "unprognostic (3.84e-2)" "unprognostic (1.26e-1)" "unprognostic (1.62e-1)" "unprognostic (1.35e-2)" "unprognostic (8.43e-2)" "unprognostic (7.74e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-3)" "unprognostic (8.25e-2)" 9.5 10.2 11.8 12.7 12.7 21.8 11.9 15.7 22.8 14.2 13.4 11.2 11.8 11.5 8.0 8.2 9.1 9.5 7.9 11.6 12.5 9.8 24.2 9.4 18.2 11.6 11.8 12.5 9.4 12.6 6.7 19.1 11.5 9.8 11.2 10.6 18.3 9.3 16.9 8.2 9.4 9.7 11.8 12.6 10.0 36.6 13.1 17.9 10.9 20.7 20.3 10.6 7.5 17.6 19.9 16.0 32.2 31.7 20.6 18.0 25.5 19.7 23.9 33.4 29.2 24.6 9.4 61.7 8.6 18.0 14.2 20.2 47.8 7.8 31.6 33.6 31.4 25.2 17.3 36.6 14.1 40.6 30.9 12.2 16.8 19.3 11.9 14.9 23.5 20.0 36.0 26.6 15.2 25.6 24.1 32.8 26.4 35.3 7.7 48.1 50.8 27.0 14.9 7.6 12.3 16.4 30.4 28.0 12.7 38.0 34.9 17.4 13.7 41.7 28.3 13.3 15.3 61.7 68.9 51.2 14.6 21.9 18.1 13.5 14.6 15.3 10.0 13.2 10.2 10.0 8.3 9.8 14.6 12.4 14.5 11.8 6.7 25.3 12.9 12.7 11.6 14.9 11.8 12.7 15.7 22.8 11.6 12.5 11.6 11.8 11.5 11.8 13.1 17.6 11.1 22.4 14.3 4.2 18.3 10.6 14.4 4.3 6.2 7.7 21.9 14.2 10.4 15.7 8.5 14.7 14.6 16.5 20.4 13.2 7.9 9.9 104.0 20.7 32.5 15.5 20.4 17.4 6.6 10.0 17.8 14.3 6.6 31.0 17.2 11.9 10.8 42.3 9.3 3.3 7.1 12.3 4.1 18.9 19.0 38.2 12.8 15.4 17.8 7.5 14.7 6.2 21.6 4.5 12.8 9.7 8.9 7.9 26.4 22.6 9.0 12.5 13.8 15.2 0.0 9.6 16.1 49.5 48.5 9.5 10.9 24.6 14.7 9.0 12.4 22.3 CCDC125 KENAE ENSG00000183323 "Coiled-coil domain containing 125" Q86Z20 5 69280175-69332809 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.0;neutrophil: 11.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.0" "Cell line enhanced" "Detected in many" "T-47d: 27.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041878 Approved Uncertain "Nucleoplasm,Nuclear membrane,Intermediate filaments" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane, Intermediate filaments" Nucleoplasm "HPA041878: AB_10796787" "prognostic unfavorable (8.06e-4)" "unprognostic (1.01e-1)" "unprognostic (2.35e-2)" "prognostic favorable (4.40e-4)" "unprognostic (1.05e-1)" "unprognostic (1.91e-2)" "unprognostic (8.21e-2)" "unprognostic (3.08e-2)" "unprognostic (4.06e-2)" "unprognostic (5.07e-2)" "unprognostic (2.52e-2)" "unprognostic (1.91e-2)" "unprognostic (2.05e-2)" "unprognostic (5.40e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "prognostic favorable (2.51e-4)" 3.3 3.9 2.3 2.9 2.4 10.9 7.0 2.6 2.8 2.8 2.7 4.8 4.9 2.7 2.6 4.5 3.6 3.3 2.1 2.1 2.5 3.8 12.9 3.3 2.9 2.7 2.7 3.0 5.1 3.2 4.3 3.9 3.2 6.9 5.6 3.2 6.6 1.9 2.0 3.8 5.4 1.3 2.0 3.5 5.9 1.4 2.5 2.4 2.9 1.1 2.4 3.2 2.9 3.5 3.1 5.0 0.9 14.0 1.6 0.9 17.9 1.8 2.6 1.2 0.7 4.4 15.3 5.5 10.4 2.1 1.1 3.9 10.3 5.3 1.1 19.4 8.1 3.5 7.5 8.6 4.2 3.9 1.9 5.5 2.6 5.7 1.7 2.8 2.0 6.6 10.6 2.3 1.1 12.5 4.9 6.1 0.2 3.9 3.2 7.2 0.0 7.4 6.7 3.5 5.8 3.6 3.7 8.2 2.8 0.2 27.0 3.9 2.3 1.1 2.0 3.4 2.9 10.8 17.8 2.0 3.5 20.5 0.5 6.9 1.0 15.0 1.1 1.0 0.9 1.1 0.9 0.8 1.7 0.8 0.8 0.5 11.4 1.1 2.8 1.3 0.7 0.9 2.3 2.4 2.6 2.8 2.1 2.5 2.7 2.7 3.2 2.0 2.5 3.5 4.7 25.6 20.4 21.9 5.7 1.0 4.0 8.5 7.4 4.7 13.4 10.3 5.9 7.2 16.8 1.8 2.1 34.2 4.4 11.0 5.9 13.7 0.9 31.6 5.6 3.4 1.2 9.2 17.2 12.2 8.5 5.5 28.5 15.1 15.8 9.9 1.8 17.9 6.1 3.3 16.7 14.1 10.2 4.1 2.7 1.9 2.1 8.7 1.8 17.8 7.8 4.5 5.2 16.1 13.4 8.6 17.1 2.2 6.9 5.5 9.6 8.9 60.7 7.4 0.0 5.3 4.7 1.8 3.1 8.5 1.0 12.4 5.2 14.1 7.9 4.8 CCDC13 FLJ25467 ENSG00000244607 "Coiled-coil domain containing 13" Q8IYE1 3 42705756-42773253 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.4;choroid plexus: 2.5;fallopian tube: 2.9;retina: 4.3;testis: 5.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 28.0;Distal tubular cells: 17.6;Early spermatids: 18.1;Endometrial ciliated cells: 23.3;Late spermatids: 18.4;Respiratory ciliated cells: 53.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047429 Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 49: Ciliated cells - Cilium organization" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA047429: AB_2680043" "unprognostic (3.34e-2)" "unprognostic (3.72e-2)" "unprognostic (2.18e-2)" "unprognostic (1.67e-3)" "unprognostic (2.19e-2)" "unprognostic (5.35e-2)" "unprognostic (4.75e-2)" "unprognostic (8.06e-2)" "unprognostic (4.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.05e-2)" "unprognostic (2.31e-1)" "unprognostic (1.83e-7)" "unprognostic (6.21e-2)" "unprognostic (2.40e-1)" "unprognostic (5.71e-2)" "unprognostic (2.04e-2)" 0.2 0.1 1.0 0.0 1.9 0.0 0.1 1.1 1.4 0.5 2.5 0.3 0.0 0.2 0.3 0.1 2.9 0.0 0.4 1.1 0.9 0.4 0.8 0.8 0.0 1.9 2.1 0.0 0.2 0.0 0.7 0.0 1.6 0.3 0.1 4.3 0.1 0.0 0.3 0.0 0.2 0.0 1.5 0.1 0.3 5.9 1.4 0.0 0.6 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.9 1.1 1.4 1.1 0.9 1.9 2.1 1.6 1.5 1.4 2.4 0.3 0.0 0.6 7.2 0.4 1.0 0.4 2.8 0.6 28.0 0.8 0.5 1.2 1.5 5.6 3.7 4.2 0.1 0.3 0.9 17.6 0.9 18.1 23.3 2.1 0.6 0.0 0.0 6.0 0.2 0.5 0.8 0.0 1.1 1.3 0.2 0.4 0.4 2.6 0.0 4.0 0.4 0.0 1.6 2.8 18.4 1.5 1.4 1.8 3.7 2.7 1.8 1.0 2.0 4.6 0.2 2.4 0.7 0.0 1.0 0.0 4.6 53.4 5.4 0.0 0.0 1.7 13.3 3.7 0.1 1.1 0.0 0.5 1.0 0.1 0.7 CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 87.6;retina: 52.5;testis: 185.7" "Group enriched" "Detected in many" 4 "Early spermatids: 780.2;Late spermatids: 2032.0" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 30.5;U-937: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nuclear membrane, Plasma membrane" "HPA010646: , HPA071015: AB_2686334" "unprognostic (2.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.29e-4)" "unprognostic (4.65e-2)" "unprognostic (4.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-4)" "unprognostic (2.58e-2)" "unprognostic (8.44e-3)" "unprognostic (4.35e-1)" "unprognostic (1.18e-4)" "unprognostic (5.27e-3)" "unprognostic (4.85e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" 1.8 3.7 37.2 1.9 24.4 0.8 1.7 42.7 39.9 5.2 6.2 20.1 1.6 9.3 2.2 1.7 3.3 2.2 5.7 24.2 34.7 0.7 0.3 1.1 2.7 30.5 54.2 2.8 0.8 1.6 6.4 1.4 26.3 12.1 3.1 52.5 1.6 13.6 4.4 0.9 4.8 11.6 34.9 1.5 4.6 185.7 87.6 5.2 1.3 4.0 1.7 13.1 3.9 30.6 1.1 1.5 11.7 7.9 6.3 5.4 2.0 4.7 6.0 4.6 4.3 1.8 1.0 6.5 0.5 6.2 18.4 2.5 7.8 0.9 4.3 17.2 7.7 10.7 3.1 0.0 2.2 1.5 22.2 6.0 0.8 5.0 0.4 4.1 2.7 10.0 4.0 6.0 1.9 2.3 8.0 3.4 16.3 0.1 5.1 19.5 2.3 2.9 0.3 2.4 7.4 20.4 2.9 3.3 5.1 4.1 0.3 3.1 2.4 7.4 4.2 3.7 3.5 3.4 1.6 6.1 30.5 46.2 1.9 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 37.2 24.4 42.7 39.9 24.2 34.7 30.5 54.2 26.3 34.9 87.6 30.6 1.6 0.0 0.5 11.4 1.1 0.5 0.9 0.1 1.8 306.0 0.6 3.8 7.5 1.5 0.7 0.0 98.0 0.1 2.2 0.0 0.0 0.7 780.2 0.3 2.2 2.0 0.0 0.4 23.3 1.5 0.3 2.6 1.5 0.1 0.0 1.9 1.1 0.0 6.8 40.4 48.0 0.1 0.0 0.6 1.6 2032.0 18.0 2.3 0.0 10.3 0.7 22.5 2.1 28.6 13.3 0.6 0.1 7.5 1.1 0.9 0.0 0.2 2.0 20.7 6.6 1.6 6.1 321.9 17.2 0.1 0.4 0.4 3.4 0.3 0.0 0.3 CCDC148 MGC125588 ENSG00000153237 "Coiled-coil domain containing 148" Q8NFR7 2 158171073-158456753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.0;testis: 3.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Early spermatids: 39.4;Excitatory neurons: 33.6;Inhibitory neurons: 53.0;Oligodendrocytes: 38.6;Respiratory ciliated cells: 34.1;Rod photoreceptor cells: 30.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;HBF TERT88: 1.8;RPTEC TERT1: 1.9;SCLC-21H: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042626 Uncertain Uncertain "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA042626: AB_10806244" "unprognostic (1.88e-1)" "unprognostic (5.90e-2)" "unprognostic (3.31e-2)" "unprognostic (1.94e-4)" "unprognostic (3.29e-1)" "unprognostic (7.65e-2)" "unprognostic (1.23e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (7.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (5.77e-2)" "unprognostic (3.35e-2)" "prognostic favorable (2.54e-4)" "unprognostic (6.57e-3)" 0.2 0.3 0.5 0.0 0.6 0.0 1.0 0.9 0.4 0.7 3.0 0.0 0.0 0.4 1.2 0.1 1.8 0.3 0.1 0.5 0.4 2.4 0.1 0.4 0.0 0.9 0.7 0.7 0.2 2.5 1.0 0.0 0.6 0.3 0.0 2.0 0.6 0.4 0.0 0.2 0.0 0.1 0.5 0.0 0.1 3.4 0.5 0.0 1.0 0.0 0.0 0.1 0.2 0.3 0.7 0.0 0.4 0.7 0.0 0.0 0.0 0.5 0.0 0.5 1.1 0.5 2.7 0.0 0.1 0.4 0.2 0.2 0.0 0.1 1.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 0.2 2.0 0.1 0.3 0.2 0.2 0.6 1.2 0.1 0.0 0.2 0.4 0.1 0.1 0.3 0.6 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.9 0.4 0.5 0.4 0.9 0.7 0.6 0.5 0.5 0.3 1.1 0.0 1.5 13.4 0.2 0.0 2.6 4.2 1.2 10.9 3.8 4.6 3.0 0.0 3.0 7.3 56.3 0.0 0.0 0.0 13.7 5.5 39.4 15.2 0.6 1.5 0.0 0.0 33.6 2.0 0.0 0.6 0.0 2.8 0.0 1.3 1.1 1.3 0.1 5.0 53.0 0.0 10.2 0.3 0.0 7.7 0.9 1.0 0.0 5.6 0.8 6.0 0.0 19.6 38.6 2.6 0.0 1.9 0.0 1.2 0.0 6.4 34.1 30.8 6.6 1.6 0.7 22.6 4.0 0.6 0.4 0.0 0.2 1.3 0.1 1.7 CCDC159 ENSG00000183401 "Coiled-coil domain containing 159" P0C7I6 19 11344684-11354944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 275.7;Late spermatids: 277.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047126, HPA054655" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA047126: AB_10961722, HPA054655: AB_2682558" "unprognostic (1.46e-1)" "unprognostic (3.05e-3)" "unprognostic (2.35e-3)" "prognostic favorable (1.87e-7)" "unprognostic (5.02e-2)" "unprognostic (1.06e-3)" "unprognostic (9.23e-3)" "unprognostic (2.40e-2)" "unprognostic (6.68e-2)" "prognostic favorable (9.46e-4)" "prognostic favorable (1.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.97e-2)" "unprognostic (5.09e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-2)" "prognostic favorable (8.62e-4)" 15.7 43.4 29.3 17.3 33.8 32.6 18.2 28.9 41.0 30.0 29.2 25.8 22.9 22.5 24.9 18.2 24.0 20.6 21.8 32.3 31.3 25.9 36.0 22.8 20.9 34.4 31.3 31.3 23.3 39.5 33.5 9.3 33.4 45.1 11.8 12.4 21.6 18.5 6.1 19.0 24.0 13.8 27.4 41.8 26.2 43.2 34.2 12.4 30.4 6.7 14.5 24.2 21.7 38.1 3.7 3.2 2.6 8.0 10.3 14.8 2.7 5.8 6.0 6.7 8.9 1.0 3.8 3.0 14.7 11.0 2.0 3.0 1.5 9.2 4.1 15.0 2.2 7.2 2.5 3.9 17.9 2.8 10.4 17.8 24.0 4.9 6.5 7.1 19.2 5.3 6.5 33.6 3.4 4.5 4.5 6.0 1.4 5.0 11.5 4.8 0.0 19.6 6.1 5.3 1.1 4.3 5.9 6.6 11.0 4.6 9.8 11.9 12.8 5.3 1.6 9.3 5.5 30.8 8.0 6.2 7.2 14.7 7.9 51.5 52.8 38.5 21.5 46.3 21.1 16.0 14.6 20.2 31.6 20.4 13.2 10.4 25.3 30.2 33.8 8.4 31.5 23.5 29.3 33.8 28.9 41.0 32.3 31.3 34.4 31.3 33.4 27.4 34.2 38.1 10.7 16.0 13.6 7.5 14.5 7.5 15.4 14.9 10.8 11.3 12.5 8.9 9.8 12.8 16.7 18.4 41.7 5.1 12.4 13.0 25.4 8.2 275.7 9.0 8.8 10.3 10.8 4.6 4.5 9.5 5.5 8.1 30.5 10.0 34.2 11.5 12.8 10.9 23.3 6.7 3.0 12.5 10.2 26.7 14.8 277.4 11.5 20.3 12.4 2.8 28.9 16.6 39.1 2.0 10.2 8.7 24.0 13.5 15.0 16.6 29.2 38.6 16.9 27.9 0.0 5.2 8.4 4.7 3.9 11.0 8.1 6.0 17.9 20.1 9.5 19.7 CCDC168 "C13orf40, FLJ40176" ENSG00000175820 "Coiled-coil domain containing 168" Q8NDH2 13 102729367-102759072 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 8.8" "Cell type enriched" "Detected in some" 11 "Early spermatids: 1011.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048184, HPA058793, HPA078547" Uncertain Approved Nucleoli,Centrosome,Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Centrosome" Cytosol "HPA048184: AB_2680303, HPA058793: AB_2683823, HPA078547: " "unprognostic (2.06e-1)" "unprognostic (7.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-4)" "unprognostic (2.09e-2)" "unprognostic (3.68e-2)" "unprognostic (2.74e-1)" "unprognostic (5.05e-2)" "unprognostic (3.61e-1)" "unprognostic (2.89e-3)" "unprognostic (1.73e-1)" "unprognostic (1.44e-5)" "unprognostic (2.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.85e-1)" "unprognostic (6.94e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 0.0 0.3 0.3 0.0 0.7 0.0 0.0 0.0 0.7 1.8 4.5 0.0 1.8 0.0 0.0 0.3 2.3 0.1 0.0 0.3 1011.0 0.2 1.2 0.6 0.0 0.0 1.1 0.4 0.5 0.4 0.0 0.4 0.0 0.4 0.4 0.0 0.3 0.0 0.9 0.0 0.0 0.6 0.0 91.3 2.1 0.6 0.0 1.0 1.6 0.0 0.0 0.5 0.6 0.4 0.0 0.7 1.4 0.5 0.0 0.2 0.0 0.0 0.0 2.9 0.7 3.1 1.5 0.0 0.0 0.4 0.9 0.2 0.2 0.2 CCDC175 C14orf38 ENSG00000151838 "Coiled-coil domain containing 175" P0C221 14 59504539-59576812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 18.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.4;Early spermatids: 11.9;Excitatory neurons: 15.9;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 11.4;Spermatocytes: 17.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 18.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004200 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli, Cytosol" "HPA004200: AB_1078743" "unprognostic (3.64e-3)" "unprognostic (8.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (3.83e-1)" "unprognostic (2.02e-2)" "unprognostic (5.98e-2)" "unprognostic (1.27e-1)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 18.4 0.5 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 18.4 0.5 0.0 0.2 0.7 0.8 0.8 0.4 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.6 0.0 8.4 0.0 0.0 1.1 0.0 0.0 11.9 5.0 0.1 0.0 0.0 1.7 15.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.3 0.0 0.0 1.5 4.8 0.0 0.3 0.0 0.0 0.1 1.5 0.0 5.0 3.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 7.4 11.4 0.0 0.4 0.3 17.7 4.4 0.0 0.0 0.0 0.0 0.1 2.4 0.1 CCDC24 MGC45441 ENSG00000159214 "Coiled-coil domain containing 24" Q8N4L8 1 43991359-43996528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 36.4;Respiratory ciliated cells: 57.6;Spermatocytes: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 1.0;intermediate monocyte: 2.2;memory B-cell: 3.5;naive B-cell: 2.2;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 5 "B-cells: 3.5;granulocytes: 1.0;monocytes: 2.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA035424, HPA061710" Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Nucleoli, Cytosol" "HPA035424: AB_2674619, HPA061710: AB_2684591" "prognostic favorable (3.06e-5)" "unprognostic (1.47e-1)" "unprognostic (1.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.65e-2)" "prognostic favorable (3.18e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.92e-2)" "unprognostic (6.38e-2)" "unprognostic (2.81e-1)" "unprognostic (7.00e-3)" "unprognostic (3.00e-1)" "unprognostic (1.74e-2)" "unprognostic (6.91e-2)" "unprognostic (1.51e-1)" "unprognostic (7.84e-2)" "unprognostic (2.15e-3)" 1.6 4.8 11.8 1.3 11.9 0.4 3.3 11.3 15.9 5.9 12.3 3.8 1.9 3.2 1.9 2.1 11.2 3.1 1.3 11.8 12.0 11.8 3.6 2.9 1.4 11.6 11.8 2.4 5.6 6.2 12.9 1.0 11.7 7.2 2.1 6.6 4.4 5.0 0.8 1.1 2.4 1.3 11.8 2.4 3.8 19.1 12.3 0.9 9.1 0.2 1.0 4.1 2.4 11.5 4.7 2.8 1.2 1.4 1.2 0.8 2.7 0.2 1.9 1.4 2.4 1.8 13.4 3.8 5.0 0.5 4.0 4.7 0.7 6.5 1.3 3.9 1.6 1.9 1.7 0.5 1.3 0.6 3.2 0.3 0.6 4.5 0.4 4.3 1.1 1.4 0.8 1.4 2.0 4.0 0.2 1.4 2.7 4.2 2.2 1.3 0.0 0.7 5.5 1.8 2.9 2.6 4.0 2.3 2.6 2.5 6.7 0.1 0.3 2.1 5.9 1.5 0.7 0.5 1.8 0.8 5.3 0.5 1.7 0.0 0.4 1.0 0.3 2.2 0.2 3.5 0.1 0.1 0.4 2.2 0.0 0.0 0.4 0.3 1.8 0.3 0.0 0.2 11.8 11.9 11.3 15.9 11.8 12.0 11.6 11.8 11.7 11.8 12.3 11.5 1.7 3.2 7.2 17.0 2.3 1.1 7.9 26.5 9.1 8.9 13.3 12.1 1.0 12.8 22.0 9.2 6.2 5.6 0.9 11.3 21.5 9.4 20.7 30.9 2.4 2.1 36.4 1.3 17.7 7.2 2.2 2.5 21.9 6.9 2.5 1.6 2.5 2.6 3.3 3.3 10.0 13.6 14.2 2.0 2.2 11.7 2.1 3.6 3.6 1.9 2.7 10.2 0.0 5.0 2.4 6.5 8.3 3.0 1.8 5.7 6.3 11.5 57.6 15.4 0.0 2.9 3.8 50.6 19.9 3.9 0.9 2.5 1.3 3.9 10.2 11.4 CCDC25 FLJ10853 ENSG00000147419 "Coiled-coil domain containing 25" Q86WR0 8 27733316-27772653 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023256 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Golgi apparatus" Cytosol "HPA023256: AB_2072067" "unprognostic (1.43e-1)" "unprognostic (5.48e-2)" "unprognostic (3.10e-3)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (6.62e-3)" "unprognostic (2.34e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-3)" "unprognostic (3.50e-1)" "unprognostic (2.69e-2)" "prognostic favorable (1.11e-7)" "unprognostic (3.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 14.0 20.9 10.1 11.8 11.4 4.9 17.4 10.5 17.1 10.1 7.3 14.3 35.5 10.4 14.3 14.2 12.9 11.9 12.2 9.9 11.3 22.5 32.3 8.8 14.0 11.1 10.5 10.8 16.3 18.3 7.5 10.6 11.5 11.6 15.7 11.1 13.5 12.0 28.4 10.3 30.8 10.3 11.3 10.5 20.0 10.9 11.9 11.4 18.8 15.2 14.2 11.7 9.4 13.0 50.1 27.9 25.8 24.7 22.8 33.0 17.2 41.0 39.5 24.7 24.0 11.2 17.9 53.6 27.7 20.9 21.2 23.1 23.6 40.0 35.5 20.3 16.4 66.9 23.1 19.3 36.9 23.8 20.8 37.1 25.9 27.1 37.6 28.7 54.0 33.7 32.2 24.6 27.8 19.2 55.3 19.9 37.9 49.4 14.8 18.7 44.4 28.8 32.3 26.7 15.1 41.7 27.5 21.0 42.8 19.0 24.0 13.1 44.6 22.5 33.4 38.9 21.7 24.5 33.8 19.5 35.0 30.8 23.8 20.3 8.9 6.6 15.2 12.6 17.8 19.8 19.6 16.1 11.6 15.5 18.3 19.3 3.2 14.3 13.4 18.1 23.2 10.4 10.1 11.4 10.5 17.1 9.9 11.3 11.1 10.5 11.5 11.3 11.9 13.0 47.5 25.6 38.9 12.4 34.8 21.4 39.6 46.5 55.2 42.6 57.3 61.6 62.5 60.1 44.5 53.3 12.5 77.6 31.2 61.6 109.5 76.9 183.1 46.8 51.0 54.2 26.5 46.7 30.5 134.6 56.0 49.3 63.2 33.3 63.9 39.3 55.0 144.5 44.7 55.5 21.9 58.6 46.8 33.5 27.2 162.9 47.2 27.4 37.4 12.2 44.4 60.2 35.0 12.1 17.7 83.7 51.1 47.4 40.7 55.2 182.1 128.6 53.7 38.9 46.0 44.4 49.1 91.1 59.6 56.7 22.3 42.4 38.7 88.1 71.2 36.0 CCDC51 FLJ12436 ENSG00000164051 "Coiled-coil domain containing 51" Q96ER9 3 48432164-48440456 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010980, HPA011408" Supported Supported Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Centrosome "HPA010980: AB_1846155, HPA011408: AB_2072212" "unprognostic (1.24e-2)" "unprognostic (5.23e-2)" "unprognostic (5.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-1)" "unprognostic (2.75e-3)" "unprognostic (4.71e-3)" "unprognostic (1.26e-2)" "unprognostic (3.04e-1)" "unprognostic (3.26e-2)" "unprognostic (7.70e-2)" "unprognostic (1.47e-3)" "unprognostic (6.46e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" 10.1 13.7 10.7 7.3 10.9 5.0 8.7 10.8 11.6 8.3 22.2 12.2 11.0 8.0 10.1 13.8 8.8 5.4 11.9 11.1 10.6 13.9 13.0 6.7 9.6 11.3 10.8 7.7 5.4 9.4 6.1 8.2 11.3 6.7 13.6 7.7 7.0 9.0 15.5 10.1 8.6 9.0 10.7 12.6 7.6 7.8 11.7 9.9 10.3 11.7 11.8 9.0 9.5 10.7 22.7 26.7 15.7 18.7 23.1 24.2 43.6 14.6 13.4 28.6 23.2 42.9 36.9 48.6 20.5 11.7 21.6 32.2 39.5 47.8 17.4 22.9 25.6 41.4 44.1 32.7 35.3 20.4 18.2 18.4 106.8 35.6 38.8 15.7 16.7 28.0 23.4 13.7 27.7 21.4 24.1 26.5 34.8 48.2 42.8 16.5 18.6 37.7 39.3 27.8 13.1 27.2 24.2 26.2 39.9 14.7 28.2 31.3 12.6 16.5 22.3 41.6 28.5 22.0 34.8 25.5 22.0 43.8 16.0 3.0 14.1 7.0 15.5 14.9 15.8 28.1 14.5 19.7 25.5 23.0 14.8 17.4 6.0 16.5 9.1 21.1 19.8 14.6 10.7 10.9 10.8 11.6 11.1 10.6 11.3 10.8 11.3 10.7 11.7 10.7 7.1 12.8 2.6 2.6 5.9 4.7 3.7 28.8 17.6 7.3 6.6 8.1 8.2 15.7 12.8 9.2 0.0 40.1 5.0 12.6 23.5 15.1 3.3 19.4 7.3 5.9 5.4 5.9 2.4 12.4 22.0 10.0 6.6 16.5 3.8 10.1 4.6 13.1 15.9 8.4 2.4 7.6 14.2 3.8 3.3 2.7 12.2 4.4 14.2 1.9 9.1 11.0 11.3 3.5 3.2 15.2 8.0 13.2 5.1 5.4 21.6 43.4 9.3 10.7 6.6 4.0 6.2 7.2 16.3 13.0 4.7 6.7 4.8 20.0 13.4 3.4 CCDC57 "FLJ00130, FLJ23754" ENSG00000176155 "Coiled-coil domain containing 57" Q2TAC2 17 82101460-82212830 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 729.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 3.7;naive CD8 T-cell: 7.6" "Lineage enriched" "Detected in many" 6 "T-cells: 7.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023315, HPA023326, HPA023342, HPA023344" Approved Approved "Microtubules,Centriolar satellite,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Microtubules "Centriolar satellite, Cytosol" "HPA023315: AB_1846159, HPA023326: AB_1846160, HPA023342: AB_2275460, HPA023344: AB_1846162" "unprognostic (2.51e-3)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (9.92e-3)" "unprognostic (1.25e-1)" "unprognostic (2.11e-3)" "unprognostic (1.33e-1)" "unprognostic (1.56e-2)" "unprognostic (3.19e-2)" "unprognostic (2.16e-1)" "prognostic favorable (5.55e-5)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.28e-6)" "unprognostic (5.19e-2)" "unprognostic (1.53e-1)" "unprognostic (2.04e-1)" "unprognostic (3.80e-3)" 5.3 8.4 3.3 5.8 5.1 8.3 8.3 6.1 8.2 13.0 6.4 8.7 7.2 9.4 6.4 3.5 11.0 6.6 4.3 3.7 1.5 12.4 7.4 8.1 5.3 2.1 1.4 12.3 10.5 7.9 16.9 3.4 1.3 14.4 3.0 9.0 9.1 5.8 4.0 5.6 6.6 3.6 0.1 6.2 7.7 12.2 1.8 8.1 17.7 1.1 2.8 6.9 6.5 3.1 5.2 10.4 5.4 6.9 3.1 5.8 6.0 3.9 3.9 2.8 2.5 3.0 7.9 2.7 3.7 3.2 2.9 12.0 1.6 7.2 1.6 2.8 10.6 4.5 20.3 6.7 4.0 4.5 5.6 5.9 5.5 5.3 6.9 6.5 3.4 3.9 5.8 1.5 2.0 7.5 8.8 8.5 1.7 3.0 4.1 4.7 2.4 3.8 5.5 6.2 18.5 11.3 3.4 17.3 6.7 3.4 9.9 5.3 3.7 11.0 10.0 4.8 8.2 11.0 1.2 0.9 8.5 5.1 4.5 0.5 0.4 0.5 0.6 0.1 0.2 0.4 0.5 0.8 0.4 0.3 3.7 7.6 1.3 0.3 0.1 1.2 0.2 1.0 3.3 5.1 6.1 8.2 3.7 1.5 2.1 1.4 1.3 0.1 1.8 3.1 5.9 25.6 62.7 19.6 35.8 11.7 22.7 23.7 19.4 22.5 82.3 66.2 5.3 17.2 41.9 29.5 41.7 36.2 45.4 27.6 9.8 15.8 116.1 44.9 15.9 6.9 42.7 14.1 72.8 17.1 34.2 9.8 36.2 19.2 34.9 33.2 7.1 101.0 29.9 25.2 54.4 46.9 30.5 42.1 35.8 729.3 8.1 28.7 33.8 13.1 39.6 10.0 48.4 16.1 10.6 18.1 26.9 10.1 36.5 20.4 31.6 13.2 52.3 66.3 6.6 14.3 9.9 13.6 6.9 21.2 18.3 12.4 40.2 10.5 37.2 23.1 CCDC59 "BR22, HSPC128, TAP26" ENSG00000133773 "Coiled-coil domain containing 59" Q9P031 12 82223681-82358805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038555 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA038555: AB_10669543" "unprognostic (1.61e-1)" "unprognostic (6.28e-3)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "unprognostic (6.73e-2)" "unprognostic (1.42e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-2)" "unprognostic (2.62e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (5.73e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" "unprognostic (1.02e-2)" 12.9 6.3 7.1 5.2 7.4 40.3 10.9 7.8 10.3 9.2 3.7 10.0 4.2 9.2 10.9 10.6 10.0 7.0 9.0 7.1 6.5 6.5 9.7 8.0 8.8 7.4 6.1 11.3 7.8 9.6 6.7 9.6 7.0 7.0 7.5 4.7 6.7 6.7 16.0 8.5 6.0 8.0 6.1 6.3 7.4 12.3 6.9 12.5 8.6 19.3 11.1 11.1 8.7 10.2 27.2 22.9 18.9 16.0 22.5 20.1 33.1 24.0 28.5 43.4 35.3 52.9 16.0 31.0 12.0 26.0 29.9 18.3 95.3 46.7 36.4 35.7 51.3 34.3 15.1 34.6 66.7 40.3 15.7 36.1 39.0 43.5 55.9 34.6 35.9 55.8 62.8 17.1 26.9 50.6 39.6 57.1 30.4 25.6 54.4 28.4 31.9 27.6 23.4 28.4 33.8 16.4 27.4 15.6 34.6 23.1 32.3 55.0 17.6 18.0 16.3 15.1 45.7 22.7 30.2 66.2 15.7 32.8 29.0 25.9 9.2 18.3 10.7 12.6 22.0 16.4 19.0 20.9 9.9 24.1 22.2 18.7 22.3 14.9 19.0 21.4 29.5 5.9 7.1 7.4 7.8 10.3 7.1 6.5 7.4 6.1 7.0 6.1 6.9 10.2 76.6 67.3 56.3 10.1 81.7 85.8 129.9 84.9 65.4 33.7 57.3 80.1 44.3 40.0 66.5 44.1 22.9 80.0 88.2 33.1 129.1 48.7 125.8 63.1 71.5 62.0 35.8 41.2 9.4 57.5 88.3 61.5 29.6 85.0 78.6 45.8 64.2 53.9 56.8 43.7 9.9 62.5 50.8 70.9 53.8 28.4 53.4 62.0 48.0 5.6 66.9 47.2 64.9 12.1 17.2 54.8 44.0 53.8 54.7 88.1 56.1 93.0 51.5 40.6 19.7 118.1 57.8 204.9 135.2 57.6 89.9 146.8 95.6 43.5 56.7 100.6 CCDC63 "FLJ35843, ODA5" ENSG00000173093 "Coiled-coil domain containing 63" Q8NA47 12 110846769-110907535 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 17.3" "Group enriched" "Detected in some" 32 "Early spermatids: 305.6;Late spermatids: 241.7" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "MCF7: 4.4" HPA061568 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No NA "Cluster 83: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Vesicles "HPA061568: AB_2684561" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.09e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 305.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 241.7 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 4.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 CCDC66 DKFZp686C0433 ENSG00000180376 "Coiled-coil domain containing 66" A2RUB6 3 56557161-56621837 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 202.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044185, HPA051937" Approved Supported "Cell Junctions,Midbody ring,Centriolar satellite,Cytosol" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Centriolar satellite" "Cell Junctions, Midbody ring, Cytosol" "HPA044185: AB_10965852, HPA051937: " "unprognostic (2.28e-2)" "unprognostic (7.74e-2)" "unprognostic (7.37e-2)" "unprognostic (2.90e-1)" "unprognostic (5.28e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.68e-3)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.05e-3)" "unprognostic (5.48e-3)" "unprognostic (6.85e-3)" "unprognostic (1.81e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-1)" "unprognostic (6.81e-3)" 2.7 3.1 3.8 3.6 3.7 3.0 5.2 3.7 4.3 4.8 4.2 4.0 3.0 4.1 5.3 2.5 5.7 3.4 2.9 3.7 4.2 4.1 2.0 3.6 4.9 3.8 3.7 6.0 3.3 5.4 4.5 3.3 3.9 4.0 4.1 7.8 3.3 3.6 4.5 2.5 2.8 4.9 3.8 4.3 3.2 3.7 3.7 5.1 4.9 2.6 4.9 3.7 3.1 3.8 5.6 2.0 5.8 3.7 8.9 5.2 4.6 6.8 6.4 9.1 7.8 4.3 4.3 15.6 1.6 3.8 5.8 2.8 3.4 6.5 10.1 5.6 4.0 9.5 9.0 4.6 6.2 12.8 3.3 4.9 8.8 7.7 5.1 8.0 6.0 7.7 9.3 2.4 7.2 4.7 10.0 7.5 9.7 4.8 7.5 3.4 5.2 8.6 5.3 1.9 2.2 4.2 8.7 5.5 5.2 4.9 1.9 5.2 3.1 6.6 5.2 6.3 9.9 4.7 5.3 8.0 4.9 14.3 5.5 10.0 1.5 3.5 4.1 2.0 5.4 2.7 7.0 5.0 1.1 1.6 8.0 5.8 0.3 5.1 2.4 1.0 14.8 2.6 3.8 3.7 3.7 4.3 3.7 4.2 3.8 3.7 3.9 3.8 3.7 3.8 39.7 22.4 22.6 42.7 41.3 28.2 20.1 30.5 15.9 68.5 18.5 21.0 30.5 30.0 29.0 22.0 108.4 23.0 51.5 7.7 29.4 23.7 202.5 58.1 33.5 28.8 21.0 40.8 93.2 10.5 14.6 29.9 18.8 13.9 34.2 38.3 37.9 8.5 18.4 52.2 95.8 11.4 22.4 35.8 27.9 109.6 54.0 20.7 26.6 51.5 56.1 36.8 105.0 70.9 96.7 14.1 9.8 47.8 28.1 25.5 11.5 20.3 51.5 111.5 32.9 38.6 30.9 55.8 46.8 12.1 29.5 16.4 51.7 33.6 14.5 11.4 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC7 "BIOT2, C10orf68, FLJ13031, FLJ32762" ENSG00000216937 "Coiled-coil domain containing 7" Q96M83 10 32446140-32882874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "brain: 28.1;testis: 78.0" "Cell type enhanced" "Detected in many" "Early spermatids: 489.6;Late spermatids: 914.3;Oligodendrocytes: 161.0;Spermatocytes: 176.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA075536 Approved "Nucleoli,Mitotic spindle,Cytosol" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli "Mitotic spindle, Cytosol" "HPA075536: AB_2686755" "unprognostic (3.43e-3)" "unprognostic (4.75e-2)" "unprognostic (1.85e-1)" "unprognostic (1.01e-2)" "unprognostic (2.69e-2)" "unprognostic (3.75e-3)" "unprognostic (2.65e-5)" "unprognostic (6.95e-2)" "unprognostic (7.57e-2)" "unprognostic (1.55e-1)" "unprognostic (2.44e-3)" "unprognostic (2.84e-2)" "unprognostic (2.95e-5)" "unprognostic (7.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" 1.0 1.2 10.9 0.9 20.3 2.4 1.3 28.1 14.5 1.4 0.0 1.1 1.2 1.3 1.5 1.2 0.8 1.1 1.1 3.1 8.9 1.1 0.7 1.2 1.6 13.7 9.1 1.5 1.5 0.8 1.7 0.9 17.0 1.1 1.5 3.0 0.8 1.3 0.7 0.7 1.0 1.2 10.7 1.1 1.2 78.0 15.6 0.8 1.9 0.6 1.4 0.8 1.0 23.7 1.4 1.5 0.4 1.8 1.2 0.9 0.6 1.2 0.4 0.4 1.2 0.3 2.0 1.0 0.6 0.8 1.1 0.6 0.7 0.7 1.6 3.6 0.2 0.5 1.3 0.4 2.1 0.6 0.9 0.8 0.3 0.8 0.3 0.8 0.5 1.6 0.8 3.4 1.5 0.2 0.4 0.3 0.4 0.7 1.4 0.9 1.9 0.1 1.2 0.3 0.9 1.0 0.2 0.2 0.9 0.5 1.0 0.8 2.0 1.0 1.2 1.3 0.7 1.1 0.8 1.0 1.3 4.0 0.6 0.0 0.3 0.0 1.7 0.2 1.7 1.2 2.7 1.5 0.1 0.6 2.9 2.0 0.0 1.8 0.1 1.0 2.0 0.3 10.9 20.3 28.1 14.5 3.1 8.9 13.7 9.1 17.0 10.7 15.6 23.7 7.4 6.4 8.6 87.8 4.8 1.9 1.1 0.5 2.2 8.9 4.1 3.9 7.2 0.0 3.0 1.8 4.2 0.7 6.2 2.0 1.9 4.6 489.6 5.0 6.1 3.5 3.0 2.1 84.3 3.4 1.1 3.7 4.1 5.4 12.6 7.0 0.0 0.0 1.7 0.0 103.3 2.8 0.0 0.0 1.2 914.3 9.6 3.1 1.8 93.7 2.4 3.5 4.1 96.0 161.0 2.8 0.5 7.2 3.8 0.5 2.4 1.1 1.1 23.1 13.1 6.0 3.6 176.0 9.4 1.3 1.1 0.1 8.6 4.6 2.1 0.6 CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Actin filaments" Cytosol "HPA067925: AB_2685925" "unprognostic (1.51e-1)" "prognostic unfavorable (9.08e-4)" "unprognostic (7.26e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-3)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.38e-3)" "unprognostic (6.03e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.53e-6)" "unprognostic (3.34e-2)" "unprognostic (3.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.35e-2)" 51.5 9.8 2.7 19.6 2.7 15.8 18.7 2.0 2.9 13.1 3.3 14.6 6.5 16.9 2.8 6.8 36.2 10.8 8.2 2.9 3.2 18.1 46.7 22.1 9.6 8.2 2.8 10.1 9.3 5.2 6.4 3.7 3.7 11.2 5.4 1.0 12.6 6.6 5.3 6.2 15.8 7.2 3.3 18.7 16.3 6.9 4.6 14.5 10.2 2.5 8.0 40.0 9.3 3.6 24.8 5.1 7.4 8.9 16.3 15.4 0.0 37.0 47.5 14.2 15.4 0.7 15.3 16.5 12.6 63.3 27.1 2.8 3.6 10.7 11.7 38.7 8.5 2.1 0.9 0.0 25.5 8.4 19.4 13.2 6.4 6.5 3.7 24.1 50.0 9.2 56.0 39.9 17.1 7.1 11.5 13.3 16.0 2.0 17.0 15.4 2.1 3.3 7.3 1.4 3.2 22.1 23.9 8.6 55.9 15.4 3.9 10.1 22.0 31.4 2.9 3.7 14.6 38.4 3.8 13.5 24.3 10.8 35.3 4.9 0.6 1.8 1.1 0.4 0.8 1.3 0.8 0.8 0.4 0.9 0.4 0.6 4.1 0.6 0.7 1.4 1.7 0.5 2.7 2.7 2.0 2.9 2.9 3.2 8.2 2.8 3.7 3.3 4.6 3.6 44.0 3.2 11.6 1.0 9.4 8.2 50.5 2.1 6.8 4.3 39.9 33.0 6.2 18.6 1.6 5.5 2.1 3.0 26.2 12.9 11.7 7.4 1.2 18.7 78.7 21.4 6.6 11.6 1.8 10.7 7.4 47.8 3.6 20.2 12.0 3.3 45.7 34.4 8.1 6.7 2.8 7.3 4.1 10.0 13.9 2.1 21.8 22.5 12.4 1.9 6.5 5.0 10.3 2.5 1.8 13.9 10.1 17.7 4.3 11.0 10.1 4.7 6.8 4.8 0.0 24.5 30.1 7.1 4.9 4.0 5.1 3.3 13.7 3.4 9.5 18.3 CCDC8 "3M3, DKFZp564K0322, PPP1R20" ENSG00000169515 "Coiled-coil domain containing 8" Q9H0W5 19 46410329-46413564 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 36.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0;Distal tubular cells: 39.2;Granulosa cells: 25.7;Leydig cells: 70.8;Peritubular cells: 57.9;Theca cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 18.5;AN3-CA: 22.2;HSkMC: 19.6;K-562: 20.3;RH-30: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041993 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041993: AB_10795388" "unprognostic (3.05e-3)" "unprognostic (2.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.39e-3)" "unprognostic (3.69e-1)" "unprognostic (6.64e-2)" "unprognostic (5.16e-2)" "unprognostic (7.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (5.72e-2)" "prognostic favorable (1.72e-5)" "unprognostic (5.43e-3)" "unprognostic (5.77e-2)" "unprognostic (4.09e-2)" "unprognostic (4.18e-3)" 4.1 16.3 4.1 2.7 3.8 0.7 8.8 3.9 2.6 13.9 7.5 3.3 0.9 13.9 10.5 1.3 22.9 4.2 24.7 3.6 3.9 11.2 0.7 4.4 0.9 5.2 7.4 36.8 13.6 9.1 12.9 6.7 5.3 6.4 1.2 1.3 10.8 7.5 2.1 3.1 2.2 6.5 4.8 2.3 2.2 5.9 4.2 5.6 9.0 2.4 0.8 7.5 7.3 4.4 1.9 0.1 18.5 22.2 4.8 6.0 8.9 9.6 0.0 2.1 0.9 0.1 0.1 0.2 12.5 7.6 0.4 0.2 0.1 15.0 1.0 0.0 9.4 0.0 0.2 1.0 16.0 0.1 0.1 19.6 0.0 5.2 15.2 0.3 0.1 0.1 20.3 0.0 6.8 0.0 0.0 1.3 13.3 0.0 0.0 0.7 24.8 0.0 16.1 0.1 2.9 0.1 0.1 0.1 0.1 14.2 0.1 4.7 1.7 1.2 4.9 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 4.1 3.8 3.9 2.6 3.6 3.9 5.2 7.4 5.3 4.8 4.2 4.4 0.7 0.0 1.1 1.3 0.0 0.9 6.5 1.5 0.0 0.4 1.8 19.3 27.0 7.2 4.0 11.0 0.0 7.5 0.1 0.0 39.2 14.8 0.4 15.0 13.9 1.2 0.0 0.0 0.0 1.1 10.0 17.3 0.0 3.9 1.3 25.7 1.1 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.9 2.9 70.8 0.6 1.8 1.0 0.0 14.6 0.0 1.5 0.1 3.6 0.0 57.9 0.0 3.7 0.0 1.2 2.4 0.5 13.1 12.3 8.3 0.4 5.5 0.0 0.1 2.1 0.2 32.7 0.0 0.8 CCDC82 FLJ23518 ENSG00000149231 "Coiled-coil domain containing 82" Q8N4S0 11 96349241-96389956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 493.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038704, HPA070631" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA038704: AB_10674835, HPA070631: " "unprognostic (3.04e-1)" "unprognostic (1.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.99e-1)" "unprognostic (4.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-3)" "unprognostic (1.37e-1)" "unprognostic (9.94e-3)" "unprognostic (5.94e-2)" "unprognostic (3.68e-1)" "unprognostic (3.41e-1)" "unprognostic (7.68e-3)" "unprognostic (1.42e-1)" "unprognostic (9.84e-2)" "unprognostic (1.44e-1)" "unprognostic (1.31e-2)" 22.2 15.1 16.5 19.6 19.7 17.1 17.6 32.0 26.6 15.9 8.7 18.1 13.0 18.4 13.9 10.4 15.9 16.8 13.7 17.4 24.6 16.6 22.1 17.9 23.4 18.2 16.5 18.3 13.8 11.8 18.2 17.4 19.5 13.0 13.3 43.2 12.8 15.8 14.3 14.3 16.9 13.8 12.4 20.3 16.7 23.7 17.9 22.3 17.9 14.9 20.1 16.7 14.5 31.1 12.9 17.9 52.4 21.0 35.9 30.0 20.8 47.0 28.0 29.9 42.4 31.1 41.3 26.1 42.8 23.1 50.5 29.1 17.5 14.7 42.5 44.5 11.7 49.1 42.7 26.0 25.6 41.5 33.2 18.3 9.2 58.9 22.8 28.0 35.9 25.3 31.4 28.1 40.5 1.1 34.9 40.2 12.0 21.6 12.7 23.7 44.2 21.0 22.6 32.9 9.6 22.7 26.6 2.7 23.0 35.5 5.0 19.5 42.6 50.1 28.1 43.7 25.3 9.5 29.9 36.0 16.2 30.7 38.6 59.4 12.5 25.1 23.7 15.2 24.5 22.5 24.7 23.6 14.0 19.3 26.9 25.5 17.9 35.7 16.2 18.7 28.5 17.9 16.5 19.7 32.0 26.6 17.4 24.6 18.2 16.5 19.5 12.4 17.9 31.1 57.9 19.2 31.4 30.7 32.9 30.5 27.0 31.5 19.4 58.9 14.0 18.5 37.2 18.6 28.9 31.3 100.1 16.6 55.1 10.7 27.4 34.6 493.8 57.6 37.0 53.6 19.8 16.4 67.0 17.5 20.5 44.9 13.7 26.4 40.4 36.4 38.6 32.1 25.2 32.0 67.0 9.0 24.4 27.4 38.4 76.8 43.8 32.5 26.6 23.4 37.2 41.6 42.2 54.3 119.7 32.3 12.2 42.9 27.2 14.5 8.8 40.1 71.8 50.6 32.9 45.4 48.4 85.4 57.0 13.0 20.5 8.2 40.7 24.9 10.3 18.7 CCDC83 "CT148, FLJ42119, KP-CoT-23, MGC34732" ENSG00000150676 "Coiled-coil domain containing 83" Q8IWF9 11 85855101-85920021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 115 "testis: 35.5" "Group enriched" "Detected in some" 46 "Early spermatids: 222.2;Late spermatids: 194.2;Spermatocytes: 160.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "MCF7: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039707, HPA039882" Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039707: AB_10795259, HPA039882: AB_10795410" "unprognostic (1.14e-1)" "unprognostic (4.09e-1)" "unprognostic (1.49e-2)" "unprognostic (4.43e-2)" "unprognostic (7.05e-6)" "unprognostic (3.52e-1)" "unprognostic (2.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 222.2 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 194.2 4.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 160.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC85C ENSG00000205476 "Coiled-coil domain containing 85C" A6NKD9 14 99500190-99604207 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058346, HPA061922" Uncertain Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Cell Junctions" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Cell Junctions" "Nucleoplasm, Nuclear bodies, Mitotic chromosome" "HPA058346: AB_2683686, HPA061922: " "unprognostic (7.17e-2)" "unprognostic (2.23e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (5.70e-2)" "unprognostic (2.61e-1)" "unprognostic (1.68e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-2)" "unprognostic (8.75e-2)" "unprognostic (3.30e-1)" "unprognostic (1.68e-3)" "prognostic favorable (2.60e-5)" "unprognostic (4.14e-2)" "unprognostic (1.95e-1)" "unprognostic (8.74e-3)" "unprognostic (9.81e-3)" 5.2 22.0 26.4 4.3 32.9 9.7 7.1 72.9 27.1 5.8 20.6 31.3 18.7 15.4 14.3 28.3 11.3 5.4 19.6 24.8 20.9 14.4 18.2 8.1 2.5 30.8 24.1 5.1 18.5 16.4 17.0 8.6 27.0 15.0 11.1 34.7 26.4 16.2 20.7 19.4 17.7 13.1 24.5 3.6 19.2 8.5 28.6 5.0 9.3 5.6 7.5 16.1 8.9 21.0 48.4 43.4 52.7 31.7 0.7 0.2 48.9 16.0 16.2 31.4 18.1 52.9 49.8 0.3 61.7 18.2 8.6 63.3 39.2 38.4 19.5 79.2 23.3 2.5 43.6 36.1 4.2 0.5 4.9 0.1 19.9 9.0 25.9 18.6 9.9 27.9 11.8 7.2 3.9 80.3 21.8 6.6 19.3 55.4 44.7 32.1 22.1 10.8 22.3 18.8 26.0 32.6 40.7 21.5 9.5 19.9 46.9 9.8 22.6 6.2 51.5 22.4 16.2 11.2 15.8 0.4 1.0 4.3 4.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 26.4 32.9 72.9 27.1 24.8 20.9 30.8 24.1 27.0 24.5 28.6 21.0 8.5 22.4 5.6 15.7 6.7 8.8 8.7 4.0 13.6 35.2 12.1 9.3 3.0 5.7 7.3 1.8 62.6 6.3 3.9 21.2 0.0 7.6 3.1 18.8 8.1 9.2 9.6 3.4 2.8 9.4 4.5 6.2 17.3 35.6 6.3 14.1 5.3 16.7 1.8 1.7 5.4 9.6 6.1 1.6 1.2 2.1 0.6 5.0 8.8 4.7 0.4 30.6 1.0 1.5 11.7 17.4 13.2 0.7 10.4 11.0 23.3 6.5 3.0 51.7 0.0 5.7 4.1 1.4 3.5 20.4 14.1 4.9 8.3 2.3 13.0 12.0 CCDC86 MGC2574 ENSG00000110104 "Coiled-coil domain containing 86" Q9H6F5 11 60842113-60851081 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 377.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041117, HPA041540" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA041117: AB_10794984, HPA041540: AB_10794299" "unprognostic (2.93e-1)" "unprognostic (6.59e-2)" "unprognostic (2.38e-1)" "unprognostic (1.47e-3)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.36e-5)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.65e-3)" "unprognostic (9.52e-2)" "unprognostic (1.25e-2)" "unprognostic (6.12e-2)" "unprognostic (4.47e-1)" "unprognostic (3.76e-2)" "unprognostic (7.54e-3)" "unprognostic (2.90e-1)" "unprognostic (2.16e-1)" "unprognostic (6.25e-2)" 25.6 26.7 12.0 14.3 13.3 10.2 20.8 13.1 14.2 12.9 11.2 14.1 11.4 16.7 3.5 19.4 15.2 6.9 16.0 12.7 13.5 19.2 13.7 11.8 11.6 13.2 13.5 13.8 23.9 377.6 24.9 11.6 13.7 23.9 5.8 8.2 12.2 8.6 34.7 22.7 12.3 10.4 12.3 12.7 16.4 48.9 12.7 8.8 12.9 13.7 8.5 20.2 14.5 14.1 83.4 110.2 26.5 76.1 21.8 35.7 36.3 54.3 42.4 98.1 52.4 95.0 53.7 98.9 100.7 31.0 69.7 73.3 94.2 65.7 48.2 35.7 101.3 51.0 45.8 133.2 70.7 80.7 82.6 39.5 48.7 90.2 61.8 14.3 75.8 53.5 166.0 46.9 50.3 97.3 125.2 122.6 107.0 48.6 156.3 81.4 39.6 253.5 37.2 33.8 59.9 38.9 34.7 79.5 64.6 17.6 80.8 30.3 45.9 93.6 59.6 131.6 118.2 41.0 66.5 109.2 78.2 86.0 118.6 1.7 13.5 4.2 9.1 29.4 9.7 9.4 9.6 8.3 29.8 9.0 11.5 10.2 1.0 6.9 9.3 16.6 9.7 10.1 12.0 13.3 13.1 14.2 12.7 13.5 13.2 13.5 13.7 12.3 12.7 14.1 9.3 0.0 2.2 2.0 8.9 37.0 22.2 5.7 28.5 12.1 9.9 10.3 0.6 4.3 4.0 1.8 8.4 17.2 5.7 5.3 7.9 18.6 25.6 6.8 9.4 12.7 7.2 8.8 2.0 12.2 20.4 10.2 9.7 7.7 5.1 7.9 3.6 3.1 18.4 3.3 1.7 5.7 6.1 2.5 16.5 15.0 11.5 7.3 16.0 1.0 5.3 3.9 4.1 1.0 1.3 19.2 3.6 6.0 8.6 24.0 4.4 7.3 1.3 8.3 19.7 10.7 19.1 74.6 18.8 21.2 31.0 8.2 7.0 12.5 11.3 18.8 CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.6;lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 21.7;HMC-1: 83.3;Karpas-707: 22.0;THP-1: 34.5;U-937: 25.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" 8.5 6.7 14.9 15.1 15.1 47.6 5.3 20.1 21.6 5.6 15.3 17.8 4.0 3.5 0.3 12.9 6.5 8.5 5.5 15.3 15.0 6.5 7.3 21.1 28.6 17.2 15.5 3.1 4.1 0.9 4.5 1.7 17.5 7.8 3.6 1.4 14.4 2.5 1.2 4.5 34.1 1.2 15.4 86.1 8.9 17.4 15.4 17.4 5.4 0.8 13.8 8.3 7.7 15.9 0.3 1.3 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 3.4 19.7 2.9 1.1 0.5 1.6 0.1 0.6 0.0 21.7 0.0 15.0 4.6 1.1 0.8 9.4 83.3 0.0 0.0 0.2 0.0 1.3 0.5 6.3 0.5 22.0 0.7 0.9 12.7 7.7 0.7 3.7 0.5 11.9 0.3 18.5 0.3 0.3 4.8 0.0 0.0 0.5 1.1 0.1 2.6 34.5 0.0 0.0 0.7 0.1 0.2 4.7 1.5 15.8 1.0 25.3 0.4 2.9 4.6 6.7 3.5 3.6 1.0 1.6 2.0 2.9 1.6 2.0 1.8 2.2 9.2 6.5 2.5 2.7 0.6 1.3 14.9 15.1 20.1 21.6 15.3 15.0 17.2 15.5 17.5 15.4 15.4 15.9 3.3 0.0 10.7 5.2 30.3 2.7 4.5 10.5 0.6 45.2 5.7 4.8 13.5 4.3 9.9 9.2 0.0 2.9 34.9 46.0 0.0 12.8 11.1 8.7 2.6 4.4 18.0 7.0 2.6 28.9 5.8 3.1 51.0 6.8 26.6 2.2 6.1 10.4 14.5 0.0 2.0 24.4 8.2 26.0 26.6 15.8 1.5 27.3 5.4 12.2 35.0 15.4 64.9 2.0 0.6 35.0 33.2 0.7 24.9 2.9 36.1 3.2 22.7 4.7 0.0 2.8 2.8 13.7 8.7 2.0 1.6 1.4 31.7 10.0 32.4 15.7 CCDC97 "FLJ40267, MGC20255" ENSG00000142039 "Coiled-coil domain containing 97" Q96F63 19 41310172-41324873 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043320, HPA043572" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Plasma membrane, Cytosol" "HPA043320: AB_10964344, HPA043572: AB_10962488" "unprognostic (9.25e-3)" "unprognostic (7.26e-2)" "unprognostic (1.68e-1)" "unprognostic (5.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (8.40e-2)" "unprognostic (1.91e-2)" "unprognostic (2.44e-1)" "unprognostic (5.93e-3)" "unprognostic (4.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-1)" "unprognostic (7.92e-2)" "unprognostic (1.65e-2)" 14.6 12.9 19.0 17.8 21.3 23.0 14.3 17.7 17.7 20.3 14.4 14.0 14.2 17.3 23.4 20.2 21.9 12.3 15.6 16.5 18.2 12.0 11.8 14.3 23.8 23.5 20.2 24.0 17.7 15.8 13.7 10.5 19.9 16.2 11.2 10.7 18.0 14.6 30.6 20.2 16.6 14.2 18.1 20.0 15.7 32.1 20.4 21.9 16.3 20.5 22.2 14.8 17.2 20.5 25.2 54.1 28.2 32.9 36.2 28.7 20.3 16.6 13.4 25.7 21.9 32.4 23.6 23.9 17.4 13.9 17.3 16.7 38.8 33.1 19.5 44.1 37.6 21.9 25.5 21.5 27.5 36.6 45.3 28.1 41.7 30.0 25.0 21.1 18.0 25.8 28.5 44.4 24.9 18.3 33.6 8.9 13.2 30.5 19.3 37.5 22.4 17.5 23.7 47.3 25.1 22.2 37.0 40.3 16.5 18.6 27.5 27.6 21.6 22.1 22.0 11.5 27.8 45.3 42.2 22.7 21.0 26.7 30.0 9.4 7.2 8.5 12.0 7.6 13.4 9.1 8.1 8.7 5.8 10.0 8.7 7.8 11.9 10.4 12.6 6.3 7.2 8.1 19.0 21.3 17.7 17.7 16.5 18.2 23.5 20.2 19.9 18.1 20.4 20.5 7.3 12.8 6.7 5.2 22.3 4.6 11.4 11.3 6.2 11.8 11.2 8.8 6.7 7.2 8.9 9.2 12.5 11.1 23.9 13.5 7.9 13.1 3.7 9.3 8.6 8.4 11.5 7.8 4.1 26.1 4.5 10.0 15.3 9.8 16.5 11.2 9.7 6.5 15.3 10.1 4.7 12.1 18.3 10.0 7.9 8.4 12.8 12.3 1.8 3.7 16.1 7.1 25.7 1.0 6.6 20.5 5.9 11.3 18.6 10.0 16.7 9.3 12.2 8.5 0.0 13.1 8.5 22.5 12.9 10.8 5.8 18.3 20.1 7.2 10.7 13.3 CCKAR ENSG00000163394 "Cholecystokinin A receptor" P32238 4 26481396-26490484 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;gallbladder: 29.2;stomach 1: 16.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Group enriched" "Detected in some" 5 "hypothalamus: 5.1;midbrain: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Region enhanced" "Detected in all" "midbrain: 12.6" HPA073900 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA073900: " "unprognostic (7.48e-2)" "unprognostic (3.70e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-2)" "unprognostic (3.36e-1)" "unprognostic (3.79e-1)" 0.0 0.0 0.5 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 29.2 0.0 0.6 5.1 0.1 0.0 0.0 0.0 0.8 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 16.5 0.1 1.1 0.3 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.4 0.6 5.1 0.8 6.9 0.6 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCNI CCNI1 ENSG00000118816 "Cyclin I" Q14094 4 77047155-77076309 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010206, HPA039853, HPA061470" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "CAB010206: AB_2073599, HPA039853: AB_2676710, HPA061470: AB_2684533" "unprognostic (3.68e-1)" "unprognostic (2.25e-1)" "unprognostic (7.59e-2)" "unprognostic (1.11e-1)" "unprognostic (4.64e-2)" "unprognostic (1.38e-1)" "unprognostic (8.57e-3)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.10e-4)" "unprognostic (3.81e-2)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" 176.7 98.4 182.1 109.8 191.0 222.9 183.6 253.4 218.2 234.8 131.4 182.7 100.0 211.0 249.1 177.9 196.5 150.7 195.7 148.1 171.8 183.8 133.7 144.8 185.2 184.0 185.9 341.6 155.2 145.2 71.1 138.0 188.6 198.9 129.8 213.2 183.0 208.9 225.8 136.4 120.8 195.6 167.5 149.1 149.0 131.7 186.1 229.2 273.5 177.8 238.8 186.6 170.5 220.7 163.3 96.0 305.0 268.6 447.6 406.7 117.0 122.5 298.4 189.9 181.5 119.3 240.6 300.1 183.2 309.4 118.9 83.4 211.7 428.9 300.2 214.0 83.7 180.3 102.1 114.0 438.1 312.0 346.4 320.4 502.6 175.1 426.2 542.6 270.1 154.3 157.2 315.9 273.4 187.7 406.3 292.5 135.2 113.9 59.0 250.7 290.0 126.5 283.5 182.7 387.3 211.8 162.9 247.2 209.2 212.6 141.2 131.6 184.6 231.0 137.0 249.0 170.4 173.7 86.1 310.9 195.4 210.6 153.3 160.7 113.2 236.7 95.6 108.0 131.2 148.2 157.0 142.0 119.5 153.7 165.2 143.8 145.8 109.3 134.0 135.3 149.7 100.0 182.1 191.0 253.4 218.2 148.1 171.8 184.0 185.9 188.6 167.5 186.1 220.7 368.4 173.1 231.3 59.7 606.6 422.9 633.0 489.3 578.8 629.5 550.2 523.5 460.5 323.1 238.7 196.8 68.8 273.7 441.5 258.8 794.3 400.9 71.0 250.5 321.3 405.5 412.3 510.9 125.8 334.3 427.4 510.9 220.2 231.2 278.4 300.9 382.7 121.5 337.0 181.7 150.3 346.6 329.6 685.1 676.5 147.5 604.0 490.4 402.0 77.8 613.0 403.2 390.3 52.3 69.1 515.1 317.6 989.2 500.8 854.8 468.4 596.6 161.4 228.7 552.2 373.3 510.8 200.4 745.5 466.1 394.8 379.5 497.3 326.5 345.9 747.1 CCNI2 FLJ16793 ENSG00000205089 "Cyclin I family member 2" Q6ZMN8 5 132747426-132754403 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.3;intestine: 3.6" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 3.5;Muller glia cells: 4.9;Plasma cells: 4.8;Undifferentiated cells: 4.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "MOLT-4: 25.7" "Low region specificity" "Detected in all" HPA056288 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 13: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA056288: AB_2683086" "unprognostic (3.84e-2)" "unprognostic (2.44e-3)" "prognostic favorable (8.21e-4)" "unprognostic (5.97e-2)" "unprognostic (3.39e-1)" "unprognostic (6.71e-3)" "unprognostic (1.21e-1)" "unprognostic (7.49e-2)" "unprognostic (3.03e-1)" "unprognostic (2.50e-1)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (1.77e-1)" "unprognostic (4.95e-1)" "unprognostic (1.71e-7)" "unprognostic (1.58e-1)" 0.2 0.3 1.2 0.9 1.9 0.1 0.2 1.3 1.5 0.5 0.0 2.6 3.6 0.1 0.3 0.1 0.3 0.4 0.3 0.9 0.8 3.1 0.0 0.5 0.8 2.2 1.3 0.2 1.2 0.0 0.6 0.1 1.6 0.9 2.7 1.1 2.6 1.3 0.3 0.3 2.1 0.1 0.9 0.4 2.4 0.7 1.5 1.5 0.4 0.0 0.9 0.9 0.2 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.4 0.0 0.6 25.7 0.1 0.4 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 1.3 1.0 0.3 0.3 0.0 0.0 0.0 0.0 1.7 4.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.8 0.1 1.2 1.9 1.3 1.5 0.9 0.8 2.2 1.3 1.6 0.9 1.5 4.3 0.2 0.0 0.5 0.0 0.9 0.1 0.4 0.8 0.0 0.1 0.4 0.1 0.6 0.0 0.4 0.0 0.0 0.4 0.1 3.4 3.9 0.4 2.2 0.4 0.0 0.1 1.2 0.0 0.6 1.5 0.2 0.3 7.1 0.5 1.3 0.0 0.0 0.0 0.1 1.7 0.5 3.5 0.0 0.0 0.0 2.1 0.3 0.4 0.0 0.0 0.0 4.9 0.0 1.0 2.4 1.5 2.3 0.0 4.8 0.6 1.8 0.3 1.0 0.2 0.0 0.1 0.2 0.2 0.7 0.0 0.1 0.0 1.9 0.1 4.2 0.6 CCNT2 ENSG00000082258 "Cyclin T2" O60583 2 134918235-134959342 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005559 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA005559: AB_1078608" "unprognostic (2.49e-2)" "unprognostic (1.19e-1)" "unprognostic (9.57e-2)" "unprognostic (1.25e-1)" "unprognostic (4.92e-2)" "unprognostic (2.65e-3)" "unprognostic (1.85e-2)" "unprognostic (1.00e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.44e-4)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.33e-1)" "unprognostic (8.51e-2)" "unprognostic (9.94e-2)" "prognostic favorable (3.28e-4)" 13.4 12.1 10.1 12.2 10.2 29.0 15.6 13.7 12.4 16.4 10.6 13.0 13.4 13.5 14.8 12.8 14.0 9.4 11.7 9.9 10.8 10.9 18.3 14.9 15.5 10.4 10.0 17.4 19.8 15.0 15.1 12.0 10.8 13.5 12.1 19.0 13.0 10.7 10.3 15.4 14.4 8.5 11.1 15.6 14.8 12.3 10.5 14.4 14.5 9.7 14.1 15.0 16.3 14.4 9.0 4.4 28.0 10.5 13.6 13.7 21.3 12.2 9.9 11.2 13.9 11.9 10.1 14.6 8.9 10.0 5.4 11.4 17.0 9.1 16.3 7.9 11.5 15.8 11.9 16.9 13.3 14.3 13.4 12.6 17.6 11.1 13.5 14.4 16.8 10.8 13.4 14.6 13.2 6.1 16.0 21.2 22.8 7.4 9.0 15.2 10.0 11.7 17.4 24.4 19.1 15.8 8.9 10.3 14.2 20.3 10.8 17.3 15.3 14.4 15.9 6.2 9.0 10.2 6.7 15.1 9.0 11.2 12.5 3.8 1.6 2.0 1.7 2.0 2.1 1.6 1.9 2.1 2.1 1.2 3.3 2.6 2.1 2.8 1.0 1.9 2.6 1.3 10.1 10.2 13.7 12.4 9.9 10.8 10.4 10.0 10.8 11.1 10.5 14.4 27.1 25.6 26.0 49.6 38.0 15.0 28.8 17.9 26.7 34.7 21.6 15.4 23.5 14.3 21.8 14.7 33.3 11.9 35.3 22.4 7.9 16.2 5.5 20.2 30.2 21.5 18.5 20.0 73.6 14.9 9.6 23.7 46.9 33.1 11.4 31.1 18.9 20.9 10.1 42.1 70.1 16.4 6.1 15.7 22.1 14.6 14.0 25.2 8.8 52.5 23.6 12.9 19.6 76.9 81.8 14.2 19.0 22.2 26.5 35.4 19.1 7.0 12.4 34.5 19.7 17.7 24.2 17.7 23.6 25.3 18.2 13.7 29.0 25.2 17.1 50.5 CCT8 "C21orf112, Cctq, PRED71" ENSG00000156261 "Chaperonin containing TCP1 subunit 8" P50990 21 29055805-29073797 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018520, HPA021051, HPA029426" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" No No 1100000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA018520: AB_1846204, HPA021051: AB_1846205, HPA029426: AB_10601796" "unprognostic (3.41e-3)" "unprognostic (2.75e-2)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (4.25e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (8.78e-2)" "unprognostic (1.37e-1)" "unprognostic (3.09e-1)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (8.26e-2)" "unprognostic (3.50e-2)" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" 72.7 125.0 62.5 99.1 67.0 99.5 100.4 70.3 84.0 78.5 78.0 87.9 77.9 74.8 88.2 83.7 80.9 64.3 116.3 66.9 74.7 102.7 92.7 70.1 140.8 64.5 65.3 88.0 95.3 100.0 40.6 107.0 69.0 77.1 102.1 71.3 70.7 72.5 121.1 75.0 78.6 85.5 66.7 88.9 68.8 79.1 68.7 141.2 78.5 145.2 154.3 122.3 50.3 66.1 437.4 243.1 319.4 233.3 220.4 302.3 350.9 340.5 219.1 386.2 317.5 548.6 269.0 858.8 229.1 237.1 466.8 174.4 632.2 391.7 441.1 364.0 348.1 1185.2 289.8 384.3 227.0 609.0 335.6 229.0 244.9 448.6 372.6 278.6 368.1 379.7 935.8 519.0 404.1 270.9 456.6 359.4 572.6 433.6 310.6 411.7 596.5 547.4 409.1 283.2 316.7 231.6 334.1 356.6 364.7 347.5 319.9 526.7 267.4 221.3 613.7 216.7 439.7 329.2 651.8 695.1 256.3 704.5 339.0 79.9 110.1 54.4 56.9 120.9 79.6 79.8 76.3 73.4 133.3 61.8 85.5 82.1 11.5 87.7 132.2 83.5 92.7 127.4 62.5 67.0 70.3 84.0 66.9 74.7 64.5 65.3 69.0 66.7 68.7 66.1 66.9 64.1 61.7 15.0 120.1 143.1 197.6 278.6 70.0 85.6 88.4 76.5 75.7 90.1 150.0 75.4 18.8 268.9 122.1 67.3 144.8 194.1 17.0 106.6 92.8 94.8 97.0 150.2 26.7 138.0 275.8 93.4 52.0 73.7 112.8 135.6 55.3 53.4 170.5 77.4 31.3 106.2 201.4 115.6 122.4 20.5 84.2 109.9 115.6 26.2 226.6 96.1 97.9 13.6 21.4 131.2 92.1 92.9 130.7 185.9 107.4 189.7 147.7 84.6 105.2 88.7 214.7 170.1 176.8 90.2 131.4 285.3 105.1 254.5 161.1 170.6 CD163L1 "CD163B, M160, SCARI2, WC1" ENSG00000177675 "CD163 molecule like 1" Q9NR16 12 7346685-7479897 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.9;lymphoid tissue: 31.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 27.5;Breast myoepithelial cells: 20.3;Excitatory neurons: 18.9;Inhibitory neurons: 16.6;Melanocytes: 14.2;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 10.8;HDLM-2: 10.1;HUVEC TERT2: 10.6;TIME: 10.1;U-87 MG: 22.7" HPA015663 Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA 660000 "Cluster 14: B-cells - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Cytosol" Nucleoplasm "HPA015663: AB_2072575" "unprognostic (1.25e-3)" "unprognostic (1.77e-1)" "unprognostic (1.42e-2)" "unprognostic (7.46e-3)" "unprognostic (2.29e-2)" "unprognostic (7.79e-2)" "unprognostic (9.39e-2)" "unprognostic (4.44e-3)" "unprognostic (1.07e-1)" "unprognostic (8.35e-2)" "unprognostic (1.08e-1)" "unprognostic (3.08e-1)" "unprognostic (1.26e-6)" "unprognostic (8.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.69e-1)" 7.5 2.0 0.6 6.4 0.7 0.1 3.7 0.4 1.4 2.0 1.3 14.6 8.6 0.9 0.6 3.0 0.7 4.2 1.3 0.6 0.5 0.7 2.6 2.7 8.0 1.7 1.3 0.3 0.4 0.3 0.5 10.6 1.8 0.5 21.9 1.8 0.8 1.2 0.4 0.6 18.5 3.2 1.2 31.8 4.5 4.1 3.6 4.6 0.7 0.9 6.3 6.1 0.3 1.0 0.2 0.5 0.3 0.0 1.1 0.4 0.0 1.0 2.1 0.2 0.9 0.0 1.7 0.0 0.4 1.0 10.8 0.0 0.0 1.4 1.6 10.1 0.0 0.0 0.6 1.6 0.0 0.7 0.1 0.3 0.0 0.3 3.9 0.7 10.6 0.0 0.2 5.6 6.3 0.0 0.0 8.1 0.2 0.0 0.0 1.9 1.8 2.2 0.0 0.0 1.4 6.5 5.1 8.0 0.0 0.4 0.0 6.6 10.1 3.5 3.2 0.3 0.0 0.1 0.1 0.0 22.7 0.5 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.4 1.4 0.6 0.5 1.7 1.3 1.8 1.2 3.6 1.0 4.1 0.0 0.0 2.6 0.3 1.3 0.0 1.1 0.0 2.5 27.5 20.3 0.7 0.0 2.1 0.0 4.2 0.1 0.5 0.4 0.0 0.0 3.1 0.0 0.1 2.5 0.0 0.0 18.9 1.4 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.4 9.1 0.0 16.6 0.1 4.1 4.1 5.2 1.5 0.0 6.4 14.2 7.5 0.2 1.1 0.0 4.5 2.4 3.3 2.6 0.0 1.2 0.0 0.0 0.1 1.2 2.1 19.7 2.1 10.5 3.4 0.8 0.1 1.3 0.3 0.3 0.0 0.1 0.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD1B CD1 ENSG00000158485 "CD1b molecule" P29016 1 158327951-158331531 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 157 "lymphoid tissue: 528.9" "Cell type enriched" "Detected in some" 21 "Langerhans cells: 153.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "myeloid DC: 19.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 19.2" "Cell line enriched" "Detected in some" 5 "MOLT-4: 587.9" HPA021824 Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" Cytosol "HPA021824: AB_1846262" "unprognostic (7.72e-3)" "unprognostic (1.55e-4)" "unprognostic (1.66e-5)" "unprognostic (1.04e-2)" "unprognostic (1.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.89e-4)" "unprognostic (2.27e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (9.53e-2)" "unprognostic (3.23e-1)" "unprognostic (3.52e-1)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (3.53e-2)" 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.0 0.6 0.0 0.7 0.1 0.0 0.0 0.1 0.2 1.0 2.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 3.3 0.2 0.1 0.0 1.0 0.7 0.0 0.0 528.9 0.3 0.1 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 118.6 0.0 0.0 0.0 0.0 587.9 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.9 153.1 0.2 0.0 7.0 1.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 551.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.1;myeloid DC: 324.9" "Group enriched" "Detected in many" 8 "B-cells: 84.1;dendritic cells: 324.9" "Group enriched" "Detected in some" 10 "JURKAT: 14.8;MOLT-4: 49.4" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" 2.7 0.8 0.0 17.3 0.0 1.1 5.0 0.0 0.2 2.3 0.0 3.4 2.0 2.4 0.6 4.5 1.8 7.7 2.0 0.0 0.0 1.2 4.1 6.5 26.2 0.0 0.0 0.9 0.7 0.6 0.2 0.1 0.0 1.8 9.4 0.0 2.8 1.3 1.0 12.2 12.0 3.1 0.0 23.0 3.7 0.9 0.0 130.4 0.7 1.1 38.2 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 49.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.6 26.8 0.1 0.1 24.7 0.3 84.1 0.1 0.0 324.9 49.1 0.2 0.0 1.1 4.1 3.7 1.5 0.5 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.2 0.0 26.6 13.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.1 0.0 0.1 1.5 0.0 0.8 0.0 0.0 0.1 1.4 0.0 0.0 3.8 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 7.1 551.4 4.5 0.0 91.2 19.6 0.0 11.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.4 0.1 0.3 0.0 7.4 0.0 1.9 0.0 0.0 0.0 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "dendritic cells: 52.1;Macrophages: 24.4;Microglial cells: 22.5;NK-cells: 90.6;Oligodendrocytes: 26.6;T-cells: 43.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "HEL: 100.0;HMC-1: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" 1.1 0.6 1.1 5.7 6.4 4.4 1.5 1.5 2.4 1.1 0.0 1.8 2.3 1.3 0.5 1.6 1.3 3.0 0.5 0.7 2.0 1.5 4.2 4.2 9.7 3.1 3.3 0.9 0.5 62.4 0.6 0.5 3.2 1.0 2.4 1.4 1.5 0.4 0.7 0.3 3.1 1.6 2.2 20.2 3.2 1.2 5.5 6.4 0.7 0.6 7.1 3.1 0.4 3.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.4 0.2 5.3 0.1 100.0 0.3 0.1 0.0 0.7 42.6 0.0 1.1 0.2 0.6 0.2 0.0 0.9 0.3 9.3 0.4 0.0 0.8 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.5 0.8 0.3 0.1 0.2 11.5 0.4 0.0 0.3 0.2 0.5 0.3 0.1 1.2 36.6 1.0 13.4 0.8 28.8 22.5 2.9 0.1 15.8 17.3 1.6 29.7 1.3 0.1 11.3 13.2 1.1 6.4 1.5 2.4 0.7 2.0 3.1 3.3 3.2 2.2 5.5 3.2 0.6 3.2 3.6 3.3 3.2 0.0 0.3 0.0 0.0 3.4 0.5 0.8 2.5 0.0 0.7 0.0 0.0 0.1 52.1 0.2 0.0 0.0 8.4 0.9 1.7 1.0 0.0 3.2 4.6 0.4 0.0 1.3 3.1 0.5 13.9 1.3 3.3 0.4 1.6 0.0 3.1 0.1 0.0 16.7 2.7 8.2 0.9 24.4 0.0 22.5 14.7 0.8 90.6 2.0 26.6 0.2 0.1 0.7 13.4 0.3 0.0 0.3 1.5 3.6 0.0 1.8 0.6 0.4 0.8 0.0 0.4 0.0 43.2 0.5 0.1 0.2 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.2" "Cell type enhanced" "Detected in some" "dendritic cells: 103.5;granulocytes: 59.5;Hofbauer cells: 114.0;Kupffer cells: 97.6;Macrophages: 90.9;NK-cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 104.4;NB-4: 45.9;RPMI-8226: 88.7" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" 10.6 7.5 6.7 31.1 7.1 24.4 4.6 7.1 31.1 2.8 7.5 9.2 11.3 3.5 1.8 3.5 3.1 14.2 4.7 6.9 7.8 3.5 14.6 18.1 27.0 11.4 8.6 1.5 3.2 1.4 3.6 13.9 13.2 4.0 8.6 1.0 4.0 2.5 1.6 4.5 13.5 11.7 9.2 95.2 4.9 1.2 12.1 14.1 2.3 2.7 11.7 9.5 2.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 5.5 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.5 45.9 0.0 0.0 0.0 0.2 0.0 88.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 17.1 0.0 845.6 170.3 481.9 226.4 374.2 48.3 18.9 45.5 67.5 159.2 6.4 16.7 52.5 560.5 456.5 387.6 149.7 3.1 197.0 6.7 7.1 7.1 31.1 6.9 7.8 11.4 8.6 13.2 9.2 12.1 12.5 1.0 0.0 7.4 0.3 7.8 0.9 0.1 0.2 0.0 0.0 0.6 1.8 0.6 1.5 0.7 0.0 0.0 0.7 103.5 0.1 0.0 0.1 0.0 0.6 0.2 2.5 0.0 5.7 0.1 0.0 1.2 0.8 0.5 0.7 59.5 0.0 2.2 1.3 114.0 0.0 0.3 0.2 0.0 97.6 24.0 0.4 0.0 90.9 3.6 5.6 36.6 0.0 225.6 1.0 0.0 0.0 0.1 0.0 14.5 0.1 0.0 0.4 0.6 0.1 6.6 0.6 0.5 0.0 0.4 0.2 0.6 1.5 33.2 0.0 0.2 0.2 CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "granulocytes: 15.2;Hofbauer cells: 32.1;Kupffer cells: 26.3;Langerhans cells: 15.3;Macrophages: 36.1;monocytes: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.1;HMC-1: 33.1;THP-1: 6.5;U-937: 16.2" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" 4.0 1.3 0.7 6.8 1.1 9.7 0.8 0.8 5.5 0.6 1.1 1.3 1.1 0.6 0.1 0.6 0.7 2.0 0.9 0.7 1.4 0.7 1.5 8.4 2.1 1.7 1.8 0.3 0.6 0.4 0.4 2.9 2.1 0.5 1.3 0.0 0.7 0.5 0.3 0.4 1.2 3.1 1.4 7.3 0.7 0.3 2.7 1.0 1.0 0.2 1.1 3.8 0.4 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 3.3 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 16.2 0.0 51.8 142.1 7.0 0.7 228.3 0.4 2.7 0.3 0.3 158.8 2.4 0.2 0.2 5.2 43.9 242.7 10.5 0.2 64.6 0.7 1.1 0.8 5.5 0.7 1.4 1.7 1.8 2.1 1.4 2.7 2.2 0.1 0.0 1.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 15.2 0.0 0.0 0.2 32.1 0.0 0.0 0.0 0.0 26.3 15.3 0.1 0.0 36.1 1.8 1.0 19.6 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 1.3 0.0 0.0 0.0 CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 298.7;Endothelial cells: 292.4;Fibroblasts: 121.9;Hepatic stellate cells: 136.0;Leydig cells: 146.3;Peritubular cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 64.3;MOLT-4: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" 202.7 28.5 29.2 13.9 28.8 5.7 122.3 27.3 34.2 95.4 21.0 54.2 13.5 71.6 42.3 28.9 82.8 54.3 153.2 25.1 27.5 49.4 5.6 69.1 18.1 29.8 29.5 35.4 18.9 21.8 10.1 219.5 30.8 36.2 19.3 2.3 37.4 33.2 58.5 67.5 39.3 75.5 24.8 21.7 34.4 20.2 32.9 19.0 79.5 68.2 17.1 74.0 61.6 28.0 0.0 0.0 0.2 0.0 3.2 0.3 0.2 0.4 2.4 0.7 1.7 0.0 0.0 0.0 6.2 0.7 0.2 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.7 64.3 1.1 0.0 0.0 1.7 0.0 66.5 0.3 0.5 0.0 0.0 0.1 3.7 0.0 0.3 0.0 0.1 0.2 0.0 0.6 0.1 0.4 2.3 0.0 9.9 0.2 2.8 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 29.2 28.8 27.3 34.2 25.1 27.5 29.8 29.5 30.8 24.8 32.9 28.0 298.7 3.2 7.8 1.6 1.0 16.7 0.2 0.3 4.6 0.6 2.1 3.0 21.9 2.8 0.1 3.7 2.1 0.2 1.5 0.0 0.0 0.5 11.6 1.0 5.2 292.4 0.0 22.3 0.2 0.2 0.3 121.9 0.5 1.0 1.3 0.1 136.0 0.6 0.4 0.0 0.1 0.0 0.0 1.2 21.8 5.0 146.3 2.4 17.8 33.7 0.3 0.2 0.0 0.5 0.3 0.2 0.0 123.0 1.6 0.3 0.0 0.1 0.0 0.2 6.6 7.7 15.2 1.0 2.0 1.5 12.9 0.1 2.2 4.0 0.0 0.3 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CDC123 "C10orf7, D123" ENSG00000151465 "Cell division cycle 123" O75794 10 12195965-12250589 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037830, HPA057540" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Golgi apparatus" Cytosol "HPA037830: AB_10671368, HPA057540: AB_2732614" "unprognostic (5.35e-3)" "unprognostic (9.06e-2)" "unprognostic (2.42e-1)" "unprognostic (5.09e-3)" "unprognostic (1.75e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (3.16e-7)" "unprognostic (2.63e-1)" "unprognostic (2.22e-1)" "unprognostic (3.20e-2)" "unprognostic (2.74e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (2.42e-6)" "unprognostic (5.35e-2)" "unprognostic (1.40e-1)" "unprognostic (3.88e-2)" "unprognostic (6.19e-2)" 44.9 40.0 38.1 53.8 44.3 73.5 45.9 40.6 46.1 43.5 39.1 54.1 37.1 39.0 46.9 50.1 42.3 34.0 61.0 41.7 41.5 42.6 55.6 35.8 69.1 40.3 38.4 31.4 29.4 42.3 33.0 50.8 40.5 35.4 58.3 29.7 31.5 39.3 49.7 44.3 39.1 53.4 41.3 45.3 35.4 35.7 40.1 65.2 41.5 52.5 81.1 63.6 34.7 43.7 155.4 187.4 148.3 157.1 125.4 136.3 117.7 137.0 94.2 194.8 205.5 274.0 186.5 259.7 123.5 153.6 116.1 157.7 237.0 223.3 172.0 176.8 206.6 199.3 142.8 266.6 162.1 151.6 159.0 131.3 118.9 214.0 126.5 98.0 206.3 320.6 224.2 114.5 178.6 135.0 208.3 133.8 221.4 223.1 76.3 195.7 111.9 234.0 173.2 86.3 72.3 140.8 139.6 165.4 152.6 120.4 180.7 179.2 200.9 107.7 127.6 167.9 166.6 112.5 233.5 320.7 135.4 155.3 69.7 133.8 99.2 242.2 103.6 117.0 108.1 158.6 114.8 115.0 139.0 170.5 93.5 99.9 233.4 121.1 129.4 116.0 143.5 167.3 38.1 44.3 40.6 46.1 41.7 41.5 40.3 38.4 40.5 41.3 40.1 43.7 48.6 32.1 35.9 18.3 51.5 54.2 49.2 162.1 39.9 28.5 28.0 32.3 56.4 24.3 75.8 35.0 6.2 120.8 55.3 25.1 86.1 91.1 7.9 26.8 39.5 49.7 20.9 36.8 33.2 82.6 138.2 46.3 26.5 26.1 49.4 36.6 34.2 37.6 101.3 26.9 27.9 31.9 105.8 25.9 34.0 10.1 41.7 37.2 46.2 21.5 79.3 43.3 45.3 19.6 23.5 84.3 34.3 45.9 44.2 46.5 30.7 73.0 62.5 29.9 39.5 32.3 59.8 50.2 41.5 46.5 74.0 77.6 51.3 72.4 47.0 50.7 CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105, DFNB32" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520277 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Early spermatids: 171.5;Late spermatids: 191.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023783 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023783: AB_1846352" "unprognostic (3.72e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (1.54e-3)" "unprognostic (1.38e-1)" "unprognostic (9.27e-4)" "unprognostic (4.88e-3)" "unprognostic (6.30e-2)" "unprognostic (3.97e-3)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (6.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (6.66e-2)" 3.6 1.5 3.9 4.6 3.1 15.5 11.3 2.7 4.2 5.4 5.2 6.0 7.3 5.3 2.7 2.2 13.0 3.3 2.3 3.7 4.5 6.3 1.8 5.9 7.2 4.3 4.9 4.6 2.0 6.0 3.6 5.1 3.3 7.6 6.0 5.5 3.4 3.0 2.6 3.8 10.7 4.7 3.5 6.7 5.8 28.2 3.6 6.4 5.8 2.8 4.4 4.4 3.3 3.2 3.3 2.6 8.1 9.3 2.9 2.1 5.7 4.1 2.7 3.9 3.1 8.9 2.7 1.6 3.0 2.4 3.2 2.5 5.6 2.3 4.0 3.4 13.7 5.8 2.3 2.9 1.1 7.8 9.8 1.8 0.6 4.3 1.4 2.0 7.0 3.3 44.7 4.8 5.8 1.4 6.3 8.7 5.1 2.1 3.3 6.8 10.6 1.7 2.8 7.2 1.5 2.7 4.3 4.1 5.6 3.9 1.9 10.0 3.1 2.2 4.9 3.8 2.5 2.4 0.9 2.5 2.7 7.3 1.3 12.2 3.6 9.0 6.9 3.3 12.5 4.5 10.9 8.2 3.5 2.9 10.2 5.5 5.4 4.4 2.3 6.2 6.0 4.1 3.9 3.1 2.7 4.2 3.7 4.5 4.3 4.9 3.3 3.5 3.6 3.2 14.1 3.2 5.5 145.9 10.6 3.7 4.5 1.7 4.6 0.4 15.8 11.0 6.6 0.0 4.4 1.8 4.2 2.7 23.2 18.4 0.0 3.0 171.5 48.3 11.8 13.5 4.8 3.8 4.3 1.9 1.0 7.0 6.6 51.1 15.2 4.8 7.1 1.0 2.8 0.0 1.4 4.0 2.0 5.5 7.3 191.7 5.0 11.1 5.4 51.5 9.3 11.4 6.2 53.8 3.6 3.1 11.2 0.7 13.5 5.2 22.9 2.5 22.5 3.8 0.0 6.2 6.0 2.3 3.6 4.9 2.4 2.2 44.1 3.0 3.7 4.1 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Horizontal cells: 753.7;Muller glia cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" 94.5 54.9 84.9 15.3 84.7 14.9 74.5 90.6 76.3 47.4 75.0 55.6 35.7 52.7 60.1 33.3 69.4 19.1 50.5 82.2 103.1 28.6 32.2 38.6 16.1 141.9 104.5 70.7 77.5 20.5 45.0 22.9 83.7 38.7 17.4 98.1 41.5 43.1 28.8 40.6 36.0 25.5 103.5 24.1 42.4 20.5 105.9 20.2 45.4 18.8 27.6 33.8 39.5 109.5 30.1 70.1 24.7 20.9 48.8 40.5 65.0 26.2 32.6 24.3 17.9 14.8 42.1 0.1 22.9 31.6 27.6 20.6 17.2 18.0 14.6 1.4 17.0 6.7 35.2 34.7 24.3 1.1 7.3 51.4 14.9 21.2 10.5 19.2 27.9 0.6 18.9 1.4 14.9 23.2 1.2 8.6 13.5 87.8 48.4 0.8 11.0 3.1 28.8 34.3 16.4 24.8 19.7 53.1 18.4 19.0 64.3 9.8 28.7 22.7 47.6 18.1 18.9 1.4 1.2 0.2 37.3 4.7 60.7 3.3 3.2 5.9 0.1 8.5 0.2 0.1 0.0 0.0 4.3 0.0 0.2 0.0 5.4 0.3 20.1 0.1 0.0 2.1 84.9 84.7 90.6 76.3 82.2 103.1 141.9 104.5 83.7 103.5 105.9 109.5 117.1 12.8 15.6 54.9 2.8 48.7 58.5 54.9 97.9 11.5 45.8 37.1 10.8 31.5 29.1 12.9 6.2 32.1 2.5 47.3 11.7 29.4 0.6 29.7 47.6 43.8 31.2 9.1 1.0 43.6 35.0 46.1 31.1 41.2 13.3 19.6 42.8 27.7 6.1 753.7 1.3 41.3 14.2 5.5 30.1 2.7 18.3 9.1 30.2 6.5 11.1 570.4 0.0 2.5 2.5 30.4 33.5 15.4 2.5 42.6 53.1 8.0 18.0 26.2 131.5 98.0 69.9 1.1 2.0 83.2 44.9 84.3 6.0 13.6 30.2 124.1 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500851-91525764 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.9" "Cell type enhanced" "Detected in many" "Early spermatids: 37.8;Erythroid cells: 23.1;Spermatocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: AB_2674807" "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 1.9 2.7 3.6 6.0 3.8 13.8 2.1 6.3 4.8 2.1 1.6 3.0 3.1 1.8 1.7 3.5 1.3 1.7 1.4 3.8 3.4 4.3 1.5 4.2 9.3 2.9 3.7 2.5 1.6 0.8 4.0 5.9 3.1 1.9 4.6 14.1 1.7 1.4 0.5 5.1 3.7 2.4 2.8 12.1 1.8 16.9 3.2 10.9 1.7 0.5 9.4 2.4 2.3 3.5 32.0 9.4 59.1 17.3 1.4 7.6 18.8 12.0 9.1 22.6 24.3 19.6 10.8 22.5 16.1 7.7 19.8 13.7 39.8 13.5 29.4 36.8 34.3 33.7 27.9 9.5 2.1 37.0 11.9 4.2 4.0 21.0 11.9 4.1 8.9 30.9 44.8 31.4 15.2 11.8 31.5 33.5 48.9 17.2 21.6 38.9 49.5 14.5 10.2 24.0 44.7 18.6 37.5 10.2 21.6 14.3 9.8 18.2 7.3 25.8 22.7 20.6 17.9 11.6 15.6 57.9 9.4 36.0 9.4 0.0 1.0 0.0 3.8 0.7 3.2 0.9 2.8 3.5 2.3 0.9 1.5 3.0 0.1 1.6 0.2 1.4 4.6 1.4 3.6 3.8 6.3 4.8 3.8 3.4 2.9 3.7 3.1 2.8 3.2 3.5 1.9 0.0 1.1 3.3 3.2 5.9 1.2 2.7 3.4 8.2 14.4 1.4 2.1 0.0 1.3 1.8 0.0 8.2 4.1 0.6 3.9 1.5 37.8 1.1 4.9 4.1 0.0 23.1 18.3 2.6 6.3 3.1 2.6 1.9 4.5 15.4 4.2 0.2 2.7 3.3 19.6 1.8 6.1 2.2 2.9 18.7 0.9 1.6 3.6 5.6 2.1 1.6 6.2 16.6 3.1 1.2 1.7 0.7 7.1 0.9 0.5 0.4 2.0 5.1 6.6 1.5 4.1 30.5 21.4 4.3 3.7 2.2 5.3 7.6 3.6 1.0 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863414 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: AB_2683182" "unprognostic (7.81e-2)" "prognostic favorable (9.40e-4)" "unprognostic (1.93e-3)" "unprognostic (8.08e-3)" "unprognostic (1.50e-2)" "unprognostic (2.84e-2)" "unprognostic (7.60e-2)" "unprognostic (1.09e-2)" "unprognostic (7.03e-2)" "unprognostic (8.75e-2)" "unprognostic (5.56e-3)" "unprognostic (1.61e-1)" "unprognostic (6.17e-2)" "unprognostic (3.36e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.48e-1)" 93.8 101.7 75.1 32.1 73.8 26.8 81.0 79.0 86.2 84.5 64.2 104.7 39.0 91.1 31.1 61.1 76.2 51.7 105.4 73.6 76.2 80.6 114.5 65.1 36.1 78.4 74.6 109.6 86.8 87.9 68.7 42.3 78.9 78.1 24.4 34.0 67.2 55.5 49.7 82.8 69.6 38.9 69.1 66.3 89.1 43.9 73.6 40.6 69.1 43.9 24.8 89.7 73.6 70.1 40.0 85.6 23.7 47.3 125.8 86.3 70.5 71.0 76.6 47.9 47.4 50.5 75.1 26.9 125.2 80.3 42.2 62.0 38.7 44.5 21.3 67.5 85.3 19.5 61.4 74.1 87.7 28.5 47.2 148.0 77.2 64.3 29.7 75.8 60.9 49.9 29.5 67.1 44.0 127.7 40.3 56.2 55.5 42.2 65.7 74.8 29.5 78.7 63.7 38.1 96.4 53.8 36.9 76.1 55.7 41.2 57.5 74.8 52.8 70.3 22.1 58.0 35.8 51.4 62.1 19.3 77.2 46.0 43.4 11.7 8.2 28.9 8.5 6.2 5.7 6.5 7.9 9.1 3.8 6.4 7.7 7.2 20.6 11.4 7.9 8.1 12.0 3.8 75.1 73.8 79.0 86.2 73.6 76.2 78.4 74.6 78.9 69.1 73.6 70.1 54.7 25.6 28.3 10.4 25.1 41.3 41.4 22.9 30.1 53.4 42.1 49.7 57.9 41.5 15.4 46.0 45.9 120.6 31.9 57.5 41.1 72.0 54.0 18.1 30.4 48.0 37.3 22.7 16.4 71.8 127.3 59.3 19.4 29.6 13.4 30.7 46.1 41.7 65.0 58.9 19.3 30.6 10.2 41.8 21.3 12.8 76.7 33.3 23.2 11.2 45.2 57.7 36.0 9.0 11.5 44.9 37.9 61.7 31.7 38.9 87.9 34.5 15.1 56.3 46.0 24.4 44.6 10.2 14.7 32.3 50.7 73.2 30.5 34.1 34.8 39.3 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696354 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 30.1 38.5 20.2 10.4 20.4 19.5 26.7 20.3 32.8 49.3 22.0 38.2 22.7 25.9 8.7 35.3 36.3 8.6 27.3 21.0 19.5 52.9 77.0 31.0 14.7 18.6 18.7 43.2 49.2 13.5 55.5 12.5 19.6 39.1 11.3 7.6 24.8 7.5 33.8 32.1 36.1 8.2 17.0 37.5 38.5 17.0 18.4 10.8 54.5 4.1 7.0 32.3 36.5 19.1 27.5 17.8 13.9 5.8 5.7 11.0 14.2 22.3 12.6 15.2 4.9 13.1 21.2 23.9 9.8 19.3 9.1 15.5 5.8 30.8 9.3 5.3 14.1 9.7 21.0 1.7 23.4 15.8 17.1 13.3 10.7 9.3 15.3 10.3 27.0 16.1 25.5 3.2 17.7 36.6 19.5 45.0 28.5 29.7 13.1 26.5 19.0 34.1 27.9 21.2 10.1 29.6 28.0 13.0 6.8 15.2 30.3 25.0 24.1 9.1 26.6 10.1 15.4 11.7 6.4 7.5 16.4 25.0 15.5 5.1 14.0 4.2 14.8 19.7 12.8 7.8 13.2 10.7 18.1 9.0 15.1 12.6 1.5 20.4 15.4 12.4 11.6 11.4 20.2 20.4 20.3 32.8 21.0 19.5 18.6 18.7 19.6 17.0 18.4 19.1 28.2 12.8 26.6 35.3 21.2 15.4 24.2 26.9 23.3 17.2 24.5 25.1 6.5 38.6 20.0 27.6 25.0 28.6 26.7 44.8 43.0 28.6 6.1 20.7 21.9 23.0 67.7 15.4 44.5 12.5 19.8 19.6 85.1 16.9 9.5 40.3 21.8 41.1 18.8 18.5 33.3 49.4 26.4 17.4 16.0 8.8 23.9 17.0 19.6 17.8 15.5 8.5 26.8 24.6 20.0 13.6 41.5 12.4 20.8 30.7 58.3 53.7 28.1 32.3 6.6 11.4 16.3 27.3 28.7 22.4 15.5 27.9 22.0 54.8 58.2 22.9 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39950121-40099580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.0;Oligodendrocyte precursor cells: 171.9;Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 11.4 10.2 8.8 14.6 10.8 28.1 11.1 19.3 9.9 12.8 6.7 11.9 10.5 13.6 14.2 14.7 15.0 12.7 10.4 8.1 10.7 12.7 15.9 12.1 21.7 10.5 8.5 20.1 12.8 17.2 8.0 13.6 8.6 11.2 13.6 19.7 12.9 11.8 11.2 12.0 12.0 12.0 7.2 16.6 12.3 19.0 10.1 19.6 20.6 14.0 20.2 13.4 10.0 14.9 28.4 16.6 28.2 27.0 24.9 24.1 19.3 22.1 23.8 19.8 24.6 17.8 19.1 51.0 12.6 23.4 34.8 33.6 23.4 19.4 29.0 25.3 17.3 22.8 20.0 16.0 23.7 34.8 23.5 14.3 25.5 22.6 30.0 22.6 23.6 23.1 39.0 34.3 20.7 14.7 28.0 24.9 40.8 20.0 19.1 30.5 18.5 20.5 18.5 28.1 20.0 28.8 27.6 59.8 19.9 36.7 24.6 43.0 28.3 27.0 26.0 17.6 30.5 28.3 26.0 41.2 19.8 30.9 35.4 7.8 2.2 4.0 4.1 1.9 2.8 6.4 3.8 3.0 1.3 10.5 3.8 3.9 5.9 4.3 3.1 3.3 3.9 1.3 8.8 10.8 19.3 9.9 8.1 10.7 10.5 8.5 8.6 7.2 10.1 14.9 47.6 44.8 72.0 131.6 49.7 21.4 18.5 15.9 29.0 47.8 36.7 27.7 30.9 25.8 37.1 31.3 70.9 13.7 91.0 23.1 7.9 20.4 13.9 54.3 51.4 30.9 18.7 5.9 179.0 15.4 9.1 31.7 30.1 72.6 17.1 95.5 19.2 23.7 13.2 37.0 166.2 17.6 14.2 23.8 17.4 9.2 26.1 31.6 14.2 145.2 27.9 22.4 53.5 171.9 199.6 28.6 12.9 17.7 50.1 21.8 15.2 12.7 32.8 69.4 6.6 38.5 32.0 36.1 33.4 34.7 26.1 12.2 49.7 56.8 20.1 25.0 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 217.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Microtubules, Cytosol" "Plasma membrane" "CAB016535: AB_785112, HPA000974: AB_2666162, HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 48.2 61.3 59.0 30.4 63.6 65.7 38.6 63.8 75.0 37.9 35.7 41.4 34.2 37.5 19.7 60.7 37.6 23.8 113.3 64.3 46.5 62.7 35.0 41.6 24.3 57.2 52.4 45.3 43.1 50.6 41.7 37.9 54.9 37.2 29.6 33.6 43.9 30.4 217.6 41.9 36.3 37.7 39.6 34.0 39.1 55.2 74.3 29.9 50.3 180.4 26.5 34.2 36.8 60.6 177.6 132.5 124.8 185.0 89.5 76.2 124.2 82.4 100.7 122.3 90.5 150.2 83.3 42.1 51.2 148.1 225.7 97.7 134.3 174.7 81.8 50.9 212.6 46.0 193.8 118.8 115.7 48.7 103.0 95.5 109.6 173.8 207.4 101.7 111.0 43.7 69.6 69.7 108.4 153.1 42.7 111.1 97.9 66.3 141.8 44.9 98.8 74.4 91.7 137.7 105.0 79.4 223.2 169.9 86.5 144.4 152.0 59.3 112.9 81.1 131.4 125.4 99.8 54.6 58.2 41.8 71.4 223.0 93.1 2.6 7.8 7.5 3.7 9.3 4.9 3.4 5.0 6.0 9.7 9.8 4.3 4.6 3.2 5.5 8.4 11.3 5.5 6.1 59.0 63.6 63.8 75.0 64.3 46.5 57.2 52.4 54.9 39.6 74.3 60.6 18.8 0.0 6.1 7.2 20.2 32.5 33.0 30.6 33.6 23.5 38.2 26.8 43.3 21.5 22.1 31.3 4.2 25.7 20.1 67.2 54.8 33.7 26.5 41.2 24.5 21.8 28.1 20.6 12.5 37.0 45.2 24.0 46.4 57.7 5.7 27.8 19.2 16.7 25.3 30.3 15.8 34.3 32.6 19.5 30.8 94.8 17.1 23.5 33.8 2.8 12.6 17.1 9.2 3.5 7.8 48.4 46.1 13.2 31.9 48.3 45.1 34.7 17.9 14.6 0.0 19.1 22.6 27.6 17.5 64.2 34.7 26.0 21.5 30.0 48.6 63.3 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Extravillous trophoblasts: 84.7;Melanocytes: 87.2;Syncytiotrophoblasts: 170.7" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 540.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 15.3 9.2 3.5 16.3 3.4 36.0 14.2 3.6 4.9 13.4 6.4 12.5 9.8 13.7 6.3 14.9 13.7 10.8 10.9 3.5 3.8 14.7 16.2 22.9 21.6 4.7 4.0 16.3 10.0 7.9 4.9 47.3 4.1 12.6 14.9 6.5 10.9 14.3 7.0 22.7 12.3 19.5 4.2 14.5 12.2 6.6 4.1 37.2 9.6 8.1 24.8 18.1 12.9 3.9 81.7 39.1 93.6 52.4 19.2 24.9 172.2 98.9 53.5 123.3 114.8 89.4 76.3 77.5 70.9 37.9 46.4 50.8 73.4 44.9 126.8 86.9 68.0 89.0 65.0 34.6 6.3 70.4 61.4 12.6 10.9 83.8 29.1 36.1 63.1 76.8 85.6 68.0 88.3 60.8 149.9 61.7 36.9 55.8 60.7 143.7 86.2 57.1 36.5 77.1 37.4 48.1 114.1 41.7 540.3 54.9 88.9 51.1 34.5 82.9 76.3 65.0 71.0 37.4 46.3 95.5 47.4 51.1 74.2 3.6 2.6 2.2 4.7 2.7 4.6 6.5 2.1 3.5 1.9 3.7 2.0 3.7 1.2 3.4 1.2 7.9 5.4 3.3 3.5 3.4 3.6 4.9 3.5 3.8 4.7 4.0 4.1 4.2 4.1 3.9 17.9 16.0 4.8 1.3 7.3 28.0 23.9 6.2 12.5 0.0 14.5 8.9 3.1 11.5 7.6 1.8 0.0 92.8 7.1 3.7 1.9 11.5 0.6 7.4 6.5 18.2 5.4 14.7 0.1 5.7 84.7 15.7 9.2 13.0 10.8 12.0 10.4 9.1 13.3 1.7 0.1 7.2 6.1 4.7 43.8 0.8 14.9 4.9 87.2 1.9 28.4 4.2 5.2 0.0 0.5 12.3 1.5 4.5 11.8 13.4 2.8 4.5 4.4 3.6 0.0 10.1 11.6 3.1 7.4 14.5 31.4 170.7 9.6 4.8 9.7 19.3 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "glioma: 175.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 2594.8;LHCN-M2: 2819.4;RH-30: 8902.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497" "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 69.7 87.8 35.0 52.8 37.9 72.0 76.6 37.7 36.9 84.3 35.9 62.6 40.2 97.4 64.2 57.2 69.4 57.1 58.9 33.6 37.1 58.5 51.5 58.0 66.8 37.1 36.9 97.3 70.9 63.5 67.7 52.4 36.8 52.7 63.3 14.5 54.4 54.1 48.2 58.9 47.2 80.4 37.3 51.5 54.8 24.1 37.3 67.6 66.0 52.7 70.6 71.6 60.7 37.6 207.1 235.7 295.7 268.0 253.7 220.7 210.4 116.1 347.9 468.5 385.7 338.2 189.1 297.4 200.2 173.6 293.2 158.0 396.3 2594.8 354.9 150.9 209.0 275.4 149.5 237.9 297.0 309.7 182.5 221.5 180.9 294.2 326.7 326.4 304.8 280.0 301.3 242.7 2819.4 304.9 296.7 256.5 347.0 208.0 249.8 267.3 8902.5 272.1 147.2 320.6 271.2 251.7 205.3 150.2 310.0 195.1 202.8 380.7 146.1 233.6 217.0 265.8 233.1 122.2 206.1 450.8 214.1 291.3 286.9 9.5 46.5 10.3 79.6 65.6 81.8 93.5 70.0 72.5 66.7 90.0 93.0 84.4 4.4 56.6 41.9 84.9 57.0 73.6 35.0 37.9 37.7 36.9 33.6 37.1 37.1 36.9 36.8 37.3 37.3 37.6 47.1 22.4 30.8 7.8 40.0 89.7 78.6 83.4 74.0 15.9 67.2 82.2 0.7 51.5 35.3 47.8 10.4 82.9 26.1 15.9 70.5 93.1 13.5 14.9 77.7 50.8 45.6 98.0 5.2 62.5 134.5 79.4 28.5 22.6 69.1 60.2 39.7 35.8 132.9 18.5 6.7 42.2 40.7 25.1 44.1 8.0 64.0 31.2 53.4 6.5 41.9 51.4 29.9 5.5 8.0 48.3 18.9 63.2 57.8 113.9 14.0 80.9 7.4 17.9 32.9 62.1 61.9 32.1 48.3 74.5 86.1 46.8 32.3 78.8 78.7 49.4 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 6.3 16.8 50.2 9.4 53.2 11.2 8.6 44.9 65.8 8.6 40.0 9.3 10.9 6.7 24.9 10.2 8.2 9.5 9.8 57.5 50.9 13.5 12.5 8.3 9.8 48.6 45.3 4.5 9.5 22.8 14.7 8.6 48.4 8.8 9.9 11.3 9.6 10.2 8.5 9.5 8.6 10.4 43.2 9.4 7.9 4.9 50.1 14.2 10.0 7.2 11.6 8.8 6.0 50.9 31.9 40.8 37.3 59.7 48.8 36.1 17.8 24.4 41.7 47.9 40.3 31.2 31.0 34.7 71.3 31.8 63.5 23.5 67.8 40.6 22.6 24.9 43.3 38.2 32.4 30.7 31.6 29.0 64.4 37.9 28.7 39.0 13.5 62.8 38.8 57.6 36.3 24.0 50.7 68.4 76.4 57.9 39.3 57.2 80.5 38.9 14.8 41.5 46.2 27.9 23.0 97.8 30.9 37.7 43.8 36.0 18.6 25.9 22.7 42.2 10.3 31.2 39.2 52.1 61.4 13.7 66.4 46.5 75.8 18.9 39.4 20.1 13.5 46.2 11.1 13.3 12.8 13.6 44.7 12.8 9.8 11.8 5.7 19.9 36.4 26.9 31.9 23.8 50.2 53.2 44.9 65.8 57.5 50.9 48.6 45.3 48.4 43.2 50.1 50.9 7.6 0.0 6.0 1.6 6.2 3.6 8.2 18.0 6.2 12.1 9.6 10.4 3.1 8.6 14.7 11.0 2.1 26.8 5.4 8.0 39.2 21.4 0.8 14.9 10.9 8.9 9.0 12.2 5.8 18.9 12.3 7.6 9.7 9.3 30.5 23.6 7.9 11.1 41.9 0.0 6.4 8.9 18.3 21.9 6.2 1.3 4.7 16.6 10.6 1.9 19.9 12.6 12.3 1.5 3.7 22.8 15.0 11.3 12.4 4.3 20.2 35.7 14.4 7.1 6.6 4.5 13.1 3.9 11.2 11.4 6.3 9.0 7.3 14.2 9.5 9.0 CDK5RAP3 "C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114" ENSG00000108465 "CDK5 regulatory subunit associated protein 3" Q96JB5 17 47967810-47981781 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022141, HPA022882, HPA027883" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Nucleoli, Vesicles" "HPA022141: AB_1846426, HPA022882: AB_1846428, HPA027883: AB_10602797" "unprognostic (4.27e-2)" "unprognostic (1.01e-3)" "unprognostic (9.95e-3)" "unprognostic (6.65e-2)" "unprognostic (5.98e-2)" "unprognostic (7.19e-3)" "unprognostic (3.84e-1)" "unprognostic (4.44e-2)" "unprognostic (7.55e-2)" "unprognostic (2.06e-1)" "unprognostic (2.59e-3)" "unprognostic (1.92e-2)" "prognostic unfavorable (3.61e-5)" "unprognostic (8.35e-3)" "unprognostic (2.30e-1)" "unprognostic (9.58e-2)" "prognostic favorable (7.31e-5)" 45.8 48.2 83.8 42.0 85.7 52.3 48.7 83.7 111.3 58.1 100.4 53.0 54.5 42.4 91.9 52.8 54.2 46.1 39.2 85.5 85.5 60.2 80.6 44.6 51.7 86.4 84.7 69.5 133.6 53.6 93.0 34.3 85.7 62.6 53.8 34.1 77.0 48.5 29.6 43.5 68.5 33.8 83.1 81.4 81.8 83.5 86.6 44.2 73.2 28.1 54.8 48.1 48.3 86.7 72.7 116.5 60.8 114.6 52.6 53.3 112.7 51.4 63.9 52.3 51.0 92.5 72.3 88.7 107.8 55.5 35.2 72.8 41.6 61.4 59.3 127.0 58.1 43.4 157.9 123.8 58.7 50.0 47.5 60.7 51.5 45.9 91.8 64.2 52.8 169.1 49.6 80.8 52.9 140.3 128.3 79.2 38.5 87.4 55.0 74.6 101.4 101.7 52.8 91.3 43.0 104.1 38.3 37.1 51.7 65.3 84.5 65.4 38.9 43.6 38.2 53.1 66.8 106.8 102.9 54.2 54.3 69.1 53.5 20.8 62.6 54.8 33.8 63.8 36.8 40.9 31.4 30.6 50.1 44.7 28.0 31.4 30.5 45.3 67.4 46.0 32.9 41.3 83.8 85.7 83.7 111.3 85.5 85.5 86.4 84.7 85.7 83.1 86.6 86.7 31.3 25.6 62.6 60.7 61.8 33.6 63.3 89.3 50.7 52.0 52.8 40.4 28.4 44.3 84.1 40.5 31.3 68.8 44.9 56.5 50.9 56.8 53.0 35.7 32.9 32.1 61.6 22.9 31.1 67.7 57.4 44.7 147.8 42.5 69.6 68.3 27.5 55.6 61.7 57.2 27.9 70.8 71.2 33.6 40.7 36.3 40.7 44.1 46.2 25.3 47.6 45.1 33.0 25.6 50.6 37.1 60.9 29.7 87.2 49.0 77.2 45.1 85.2 52.6 32.9 34.3 33.2 132.8 45.7 31.0 25.9 61.6 53.0 38.6 56.8 56.6 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 121.0;Extravillous trophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 169.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453, CAB079975" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, CAB079975: , HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 13.4 19.8 9.4 9.5 10.2 29.1 14.8 10.9 12.9 17.5 11.5 13.7 13.3 12.1 12.9 37.3 12.5 6.4 12.4 9.5 10.5 18.4 13.6 12.7 4.8 9.7 9.7 11.7 14.1 3.2 18.2 16.2 9.8 13.7 7.4 12.8 18.9 4.8 26.8 25.3 12.2 7.7 9.8 12.6 13.5 30.6 10.0 9.3 13.2 15.0 13.3 16.1 19.9 9.4 42.8 5.9 19.4 30.6 6.4 24.4 169.5 30.9 37.5 46.2 42.9 62.2 64.5 3.7 36.4 36.8 34.2 65.3 10.8 31.3 40.6 9.0 3.1 8.6 21.4 25.9 32.8 17.9 33.8 7.1 61.3 1.8 46.0 24.5 32.5 22.3 16.3 16.1 13.3 33.3 9.4 51.7 20.7 2.8 25.4 12.3 0.7 27.1 42.6 25.4 8.6 17.5 11.6 50.4 42.4 28.1 44.9 39.3 7.4 17.1 27.4 33.1 18.2 14.4 30.4 16.5 31.4 10.2 15.5 27.9 7.9 16.2 5.3 8.9 7.9 10.6 7.8 10.6 7.3 14.5 5.9 6.4 8.2 8.6 4.7 8.9 10.5 6.1 9.4 10.2 10.9 12.9 9.5 10.5 9.7 9.7 9.8 9.8 10.0 9.4 12.2 16.0 13.2 10.7 7.8 57.7 21.4 32.9 15.4 6.4 12.3 14.7 11.3 10.0 20.2 5.5 12.5 121.0 11.7 10.2 15.6 27.8 26.8 33.1 10.7 11.6 3.0 9.9 17.6 21.6 343.6 13.0 9.7 27.2 15.8 7.4 7.1 6.7 24.0 1.7 13.7 12.3 20.3 8.5 6.0 7.9 7.5 8.5 7.2 11.2 11.6 10.4 15.5 8.0 11.9 29.3 16.2 7.2 5.8 28.2 12.3 29.3 42.4 8.7 26.3 10.0 12.5 70.1 18.6 15.9 41.9 64.6 11.4 6.8 13.2 29.8 CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 206.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 575.3;Extravillous trophoblasts: 1531.7;Syncytiotrophoblasts: 2241.2;Theca cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 155.1;non-classical monocyte: 376.4" "Lineage enriched" "Detected in many" 14 "monocytes: 376.4" "Cell line enhanced" "Detected in many" "EFO-21: 12.0;HeLa: 12.8;RPMI-8226: 18.7;SH-SY5Y: 33.0;SiHa: 25.2;SK-MEL-30: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: AB_1079548" "unprognostic (5.49e-3)" "unprognostic (2.62e-1)" "unprognostic (9.82e-3)" "unprognostic (5.79e-3)" "unprognostic (4.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-1)" "unprognostic (3.31e-2)" "unprognostic (8.53e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" 127.4 182.9 8.2 3.3 38.0 1.7 92.5 43.3 18.7 73.7 6.5 48.1 1.4 70.6 0.2 29.9 70.7 0.8 82.6 11.7 18.8 149.5 8.3 34.5 0.2 55.1 33.5 206.4 28.5 0.2 27.8 28.1 45.0 33.1 0.2 0.5 21.7 1.5 60.3 26.6 25.0 0.4 31.8 20.6 54.1 8.6 34.3 0.2 17.0 0.9 0.4 75.0 49.4 95.3 0.1 0.1 1.6 0.0 0.4 0.5 1.8 0.3 0.6 0.3 0.0 3.3 0.4 0.0 12.0 0.2 0.1 0.5 0.3 0.3 0.1 5.6 1.2 0.1 12.8 0.0 3.3 0.0 1.4 2.4 1.6 0.0 0.2 0.1 0.3 0.1 2.7 0.8 0.5 0.1 0.0 6.0 10.6 0.5 4.0 2.2 0.0 18.7 0.7 0.0 3.5 33.0 25.2 0.3 15.2 0.9 0.2 2.8 0.4 0.0 2.2 0.0 0.1 7.3 0.0 0.1 0.0 1.8 6.8 9.1 1.2 0.9 0.4 155.1 1.8 0.0 0.4 0.6 26.9 0.3 1.0 0.3 2.2 0.0 376.4 0.2 0.7 14.7 8.2 38.0 43.3 18.7 11.7 18.8 55.1 33.5 45.0 31.8 34.3 95.3 357.3 3.2 5.8 1.0 11.6 10.7 81.7 4.9 30.7 11.9 81.0 150.5 45.3 61.5 10.8 31.3 6.2 575.3 46.9 20.3 15.6 9.8 176.5 38.8 101.5 100.8 106.5 0.8 0.6 0.6 1531.7 141.0 17.9 56.2 0.0 31.2 74.6 4.0 91.0 8.4 1.2 25.0 12.2 23.5 23.2 276.4 74.3 54.9 35.6 4.7 14.1 68.3 0.0 3.5 65.7 4.3 4.2 44.4 12.9 64.6 4.0 78.5 7.5 27.4 32.9 238.3 71.4 2.1 3.5 17.3 11.8 2241.2 25.1 781.8 15.2 71.8 CDR1 "CDR, CDR34, CDR62A" ENSG00000288642 "Cerebellar degeneration related protein 1" P51861 X 140783578-140784366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1331 "brain: 44280.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 140.3;Horizontal cells: 35.3;Muller glia cells: 140.9;Rod photoreceptor cells: 34.1" "Region enhanced" "Detected in all" "cerebellum: 44280.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.9;BJ: 16.0;MOLT-4: 10.6;U-87 MG: 61.7" "Not detected" "Not detected" HPA073147 Approved "Nucleoplasm,Golgi apparatus,Centrosome" NA NA "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus, Centrosome" Nucleoplasm "HPA073147: AB_2686574" 7.9 3.1 1936.4 0.7 9723.2 0.0 0.0 44280.9 11546.5 0.0 0.0 0.3 0.3 1.2 0.0 2.0 0.6 5.1 5.1 967.3 404.7 0.2 0.0 1.3 0.2 4300.7 2927.3 0.3 10.6 0.0 1.1 8854.8 0.4 0.0 20.8 1.4 0.0 0.4 33.2 0.3 0.0 1798.6 2.4 1.1 0.2 3637.0 0.0 2.2 0.0 0.0 1.7 21870.1 0.0 4.2 8.9 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 10.6 0.0 2.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 2.1 3.7 0.1 0.0 0.0 2.9 0.0 3.0 0.0 0.0 0.0 61.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1936.4 9723.2 44280.9 11546.5 967.3 404.7 4300.7 2927.3 8854.8 1798.6 3637.0 21870.1 0.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 140.3 0.3 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.7 1.1 0.0 0.0 0.4 0.0 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 35.3 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.2 0.0 0.0 0.0 140.9 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 34.1 0.0 1.6 1.2 0.0 0.0 0.1 3.1 0.0 0.1 0.1 0.0 0.1 CDV3 H41 ENSG00000091527 "CDV3 homolog" Q9UKY7 3 133573686-133590261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 559.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 1103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029761, HPA029762, HPA029763" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA029761: AB_10600193, HPA029762: AB_10611247, HPA029763: AB_10601679" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (4.06e-2)" "unprognostic (4.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.21e-6)" "unprognostic (1.20e-1)" "unprognostic (3.30e-1)" "unprognostic (8.45e-3)" "unprognostic (3.29e-3)" "unprognostic (1.13e-1)" "unprognostic (2.36e-1)" "unprognostic (7.83e-2)" "unprognostic (1.48e-2)" "unprognostic (9.87e-2)" "unprognostic (7.59e-3)" 117.0 68.6 39.1 113.7 42.0 161.3 73.0 40.6 42.9 59.3 48.3 80.0 57.5 60.6 54.9 78.7 51.6 76.4 74.5 37.0 47.1 64.4 112.9 83.6 159.3 46.0 41.8 57.9 84.3 85.8 43.0 108.5 46.0 43.2 70.8 49.2 52.7 47.7 250.9 55.0 65.5 75.7 44.6 121.6 89.0 95.9 45.8 194.5 97.4 155.9 165.6 104.3 49.3 47.8 376.2 85.5 147.6 98.0 166.7 203.6 174.5 201.6 261.1 197.6 194.7 213.4 147.0 473.9 298.0 227.4 229.2 158.2 213.5 202.0 366.4 306.1 80.1 282.3 93.2 130.9 258.2 318.7 173.4 194.7 206.7 178.2 473.4 139.6 254.5 137.9 205.7 309.9 289.5 107.1 260.9 180.9 148.9 161.6 108.2 156.8 197.6 382.2 206.9 150.7 116.5 87.8 192.0 140.4 246.0 210.0 456.3 190.8 316.4 209.4 198.5 168.5 202.7 446.9 363.2 1103.9 117.0 187.8 124.7 14.3 10.5 17.6 13.0 12.3 13.5 11.1 12.2 13.2 9.7 7.0 9.7 15.2 9.7 6.4 13.7 15.9 24.0 5.7 39.1 42.0 40.6 42.9 37.0 47.1 46.0 41.8 46.0 44.6 45.8 47.8 116.3 57.7 69.8 7.2 114.9 145.9 217.3 19.5 63.7 22.6 97.6 77.2 86.2 74.4 34.4 84.6 10.4 51.6 169.7 158.0 37.2 42.1 324.7 174.0 160.5 99.5 47.2 59.5 13.2 87.6 82.0 93.7 88.7 314.4 45.0 63.0 91.1 97.2 118.5 23.5 12.3 102.4 10.2 146.8 117.7 559.5 34.2 145.0 55.2 17.8 100.4 109.5 90.6 8.0 14.5 88.1 101.2 35.7 239.4 320.2 26.9 74.4 27.4 29.9 26.3 120.9 92.5 21.2 30.9 94.0 128.3 35.2 126.5 124.4 90.1 219.5 CDX4 ENSG00000131264 "Caudal type homeobox 4" O14627 X 73447254-73455245 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "skin 1: 1.1" "Cell type enhanced" "Detected in some" "Spermatogonia: 1.2;Suprabasal keratinocytes: 1.1" "Cancer enriched" "Detected in single" 11 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043714, HPA056528" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear speckles" Cytosol "HPA043714: , HPA056528: AB_2683166" "unprognostic (1.97e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEBPE CRP1 ENSG00000092067 "CCAAT enhancer binding protein epsilon" Q15744 14 23117306-23119255 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 51.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 6.6;Kupffer cells: 1.4;Macrophages: 2.3;monocytes: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 218 "eosinophil: 750.4" "Lineage enriched" "Detected in many" 250 "granulocytes: 750.4" "Group enriched" "Detected in some" 4 "HL-60: 233.8;NB-4: 122.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002928, CAB005113" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Plasma membrane, Cytosol" "CAB005113: AB_631240, HPA002928: AB_1078494" "unprognostic (1.33e-2)" "unprognostic (4.76e-2)" "unprognostic (4.19e-2)" "unprognostic (2.04e-1)" "unprognostic (5.01e-2)" "unprognostic (1.66e-3)" "unprognostic (2.84e-1)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (5.69e-2)" "unprognostic (9.03e-2)" "unprognostic (2.22e-1)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.57e-2)" "unprognostic (8.19e-2)" 0.1 0.0 0.1 1.6 0.1 51.8 0.0 0.0 0.2 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.5 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 3.2 0.3 0.1 3.4 0.8 0.0 0.3 0.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 233.8 39.6 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.9 122.5 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 26.3 0.0 0.5 3.0 750.4 0.0 0.6 0.1 0.5 1.0 0.4 1.5 0.5 1.8 1.5 3.4 0.0 0.3 1.5 0.0 1.8 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 1.4 0.6 0.1 0.0 2.3 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.6 0.1 0.0 0.0 CELF2 "BRUNOL3, CUGBP2, Etr-3, NAPOR-2" ENSG00000048740 "CUGBP Elav-like family member 2" O95319 10 10798397-11336675 "Predicted intracellular proteins" "mRNA processing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.9" "Cell type enhanced" "Detected in many" "Astrocytes: 558.0;Excitatory neurons: 1676.4;Inhibitory neurons: 576.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 200.2;HMC-1: 186.2;REH: 86.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016395, HPA035813" Enhanced Supported "Nucleoplasm,Vesicles,Midbody ring" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Midbody ring" "CAB016395: AB_2086271, HPA035813: AB_2674797" "unprognostic (1.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.90e-2)" "unprognostic (3.55e-2)" "unprognostic (9.00e-2)" "prognostic favorable (7.61e-4)" "unprognostic (1.57e-1)" "unprognostic (3.77e-2)" "unprognostic (4.20e-2)" "unprognostic (5.22e-2)" "unprognostic (2.60e-3)" "unprognostic (2.83e-2)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.45e-1)" 39.6 5.7 33.7 30.7 42.7 78.9 17.7 0.2 42.0 14.2 0.0 16.5 9.2 15.0 5.0 21.4 13.3 17.2 37.5 42.5 7.2 3.0 4.3 28.2 42.4 0.9 13.9 46.8 4.4 3.5 6.5 8.6 0.4 14.1 17.9 35.4 9.6 12.2 17.6 8.6 23.4 23.2 8.6 31.1 10.3 7.6 23.7 60.7 8.5 15.0 29.4 16.2 8.0 21.0 0.1 0.0 47.6 0.0 7.4 2.7 5.3 7.0 0.2 1.1 0.2 0.1 0.0 0.1 5.3 6.1 0.0 0.1 6.8 0.2 0.4 40.4 11.9 200.2 0.7 0.0 1.7 58.0 186.2 3.0 0.3 0.4 0.0 0.7 6.7 70.6 9.3 80.7 59.6 0.0 71.9 42.0 19.3 0.0 0.0 86.7 50.8 18.0 3.4 0.0 7.1 0.5 0.1 0.2 51.1 15.2 0.0 39.0 0.1 8.9 2.5 29.9 0.1 30.7 30.1 9.3 2.9 68.8 21.6 68.0 43.2 90.8 54.8 57.5 69.2 48.1 54.1 60.5 53.4 51.0 56.1 52.7 115.1 73.5 67.8 37.9 60.9 63.5 33.7 42.7 0.2 42.0 42.5 7.2 0.9 13.9 0.4 8.6 23.7 21.0 20.4 160.3 147.3 558.0 165.6 19.9 3.4 5.8 12.5 68.2 18.8 13.7 122.7 5.7 22.4 12.9 102.2 1.1 233.5 11.8 15.6 1.6 135.9 5.3 11.3 34.7 59.3 45.2 1676.4 2.1 0.9 106.0 11.2 17.0 128.5 0.7 13.2 5.1 90.0 134.6 576.9 37.5 24.4 261.4 134.3 110.3 111.6 192.9 115.6 376.6 263.6 90.5 256.4 324.7 21.6 1.5 16.9 89.5 124.3 10.1 2.4 1.0 5.8 99.2 52.6 117.6 33.7 4.1 11.5 5.7 14.5 1.9 232.5 8.5 23.8 2.4 CEMIP2 TMEM2 ENSG00000135048 "Cell migration inducing hyaluronidase 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 92.5;placenta: 79.6" "Cell type enhanced" "Detected in some" "Adipocytes: 105.8;dendritic cells: 378.1;Glandular and luminal cells: 137.3;Plasma cells: 155.1;Syncytiotrophoblasts: 89.8;T-cells: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 143.4;BEWO: 117.4;OE19: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017080, HPA044889" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Vesicles, Cytosol" "HPA017080: , HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" 25.1 5.4 9.7 24.8 6.5 29.7 11.1 9.7 8.3 5.1 15.0 24.2 27.2 7.2 2.7 6.6 5.6 41.5 7.7 19.0 2.8 10.4 60.2 35.0 23.1 4.1 3.6 2.2 19.3 92.5 4.6 79.6 4.9 7.0 28.0 17.3 11.1 8.0 4.8 6.1 23.7 11.7 4.1 15.9 33.2 6.8 8.2 18.6 9.4 8.6 20.7 32.0 3.4 5.5 22.5 85.0 143.4 6.6 13.7 22.9 117.4 81.7 48.7 51.6 40.5 24.3 31.3 0.4 20.0 18.8 11.6 35.2 38.6 9.9 73.2 2.5 11.2 38.9 20.9 68.7 23.9 0.4 9.8 28.0 11.4 38.9 8.1 14.0 68.2 3.3 4.7 10.2 28.8 15.1 4.1 0.6 28.2 144.3 8.6 3.3 39.9 2.4 31.6 60.4 6.3 0.6 19.3 12.5 20.5 45.2 8.8 1.3 30.3 33.7 38.3 17.4 39.3 1.8 37.8 0.9 6.1 3.9 43.7 0.1 1.3 3.1 1.4 1.1 0.3 0.4 1.5 1.3 0.5 3.0 2.1 1.0 2.3 0.3 1.0 0.1 2.3 0.9 9.7 6.5 9.7 8.3 19.0 2.8 4.1 3.6 4.9 4.1 8.2 5.5 105.8 0.0 0.0 0.0 47.6 0.0 0.0 0.0 0.0 0.0 58.7 46.7 0.0 0.0 0.0 14.7 0.0 47.9 378.1 0.0 0.0 20.2 0.0 42.1 24.2 14.7 0.0 0.0 0.0 36.2 14.4 4.3 0.0 137.3 0.0 3.8 0.0 0.0 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 30.8 0.0 0.0 155.1 0.0 0.0 11.6 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 89.8 86.1 3.1 0.0 0.0 CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: AB_2683654" "unprognostic (4.35e-1)" "unprognostic (6.41e-3)" "unprognostic (4.31e-3)" "unprognostic (7.85e-2)" "unprognostic (6.31e-2)" "unprognostic (3.85e-3)" "unprognostic (6.40e-2)" "prognostic favorable (9.67e-4)" "unprognostic (3.22e-2)" "unprognostic (7.13e-2)" "unprognostic (8.35e-2)" "unprognostic (4.32e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-3)" 1.5 1.6 2.5 1.0 3.2 3.6 3.3 5.6 2.6 2.8 0.2 2.0 1.1 3.1 2.3 1.5 2.9 1.1 1.5 2.2 2.0 2.0 1.4 1.5 1.8 1.3 1.8 5.6 3.8 1.5 2.5 1.3 1.7 2.9 1.2 2.7 2.0 1.6 1.1 2.3 1.8 1.5 1.3 2.0 2.1 1.7 1.7 2.0 3.1 1.1 1.5 2.0 2.3 2.8 0.4 0.5 1.6 0.9 1.9 1.1 0.9 0.6 0.5 0.7 0.5 0.7 1.3 2.7 0.8 0.8 0.2 0.8 2.2 0.9 1.2 0.8 0.4 2.1 0.9 0.9 0.6 3.9 0.8 1.4 0.3 0.5 1.3 1.2 0.4 1.8 3.0 1.6 1.1 0.7 5.3 3.5 1.8 0.8 0.3 2.4 4.0 0.9 1.0 0.8 2.8 1.3 1.2 2.5 0.7 1.6 0.7 1.3 0.4 1.0 0.5 0.7 0.5 1.3 0.5 2.7 1.1 2.2 0.6 0.5 0.2 0.5 0.7 0.4 0.3 0.8 0.8 0.9 0.2 1.1 1.2 0.9 0.2 0.5 0.2 0.4 0.4 0.2 2.5 3.2 5.6 2.6 2.2 2.0 1.3 1.8 1.7 1.3 1.7 2.8 53.1 32.1 35.5 38.8 68.4 15.2 25.3 17.7 35.9 53.7 26.0 32.3 24.3 18.6 31.6 16.5 14.6 20.2 75.0 17.7 11.7 13.5 4.1 21.0 39.0 33.7 13.1 31.7 58.5 16.7 12.9 41.3 35.7 25.1 26.6 39.8 23.2 14.1 12.8 52.2 57.0 18.4 18.3 16.7 7.9 5.5 34.8 26.7 16.0 31.9 27.4 31.6 60.8 46.3 74.6 14.6 13.0 25.6 89.1 15.3 24.2 20.4 27.2 29.0 19.7 54.1 34.2 47.2 44.4 34.7 9.2 18.3 69.8 43.3 16.4 23.9 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 100.4;Spermatogonia: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 106.4;JURKAT: 105.1;NTERA-2: 103.4" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" 4.0 4.7 11.7 0.6 11.3 5.1 4.6 9.3 11.7 4.4 7.1 9.1 9.8 5.9 3.5 0.5 6.6 1.3 5.6 11.9 13.2 3.4 10.7 2.6 1.2 11.6 11.0 6.2 4.0 3.9 7.0 1.2 10.0 3.1 8.0 4.0 1.5 4.0 21.1 0.8 10.6 4.0 11.6 1.1 13.2 10.3 11.4 17.1 2.4 9.5 1.2 4.2 1.7 11.9 10.7 20.4 106.4 53.4 3.0 2.7 18.2 8.7 8.6 26.5 20.0 20.5 4.7 42.5 17.0 6.5 4.9 3.2 69.3 0.6 16.8 0.0 85.9 10.1 5.0 41.1 29.2 10.1 0.0 7.6 2.8 31.6 18.7 3.0 15.2 105.1 17.4 0.0 8.0 1.8 80.2 34.2 103.4 69.1 0.0 57.1 4.1 4.9 6.1 15.4 56.8 43.9 22.2 0.3 5.2 48.6 0.3 24.8 1.0 0.0 8.6 1.2 0.0 0.0 0.0 24.9 0.0 14.0 0.6 0.0 0.0 1.3 0.1 0.0 0.0 1.4 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.7 11.3 9.3 11.7 11.9 13.2 11.6 11.0 10.0 11.6 11.4 11.9 13.3 0.0 2.7 3.9 13.7 1.0 29.7 0.5 4.6 40.0 22.5 31.6 4.2 30.0 4.4 1.8 4.2 19.6 19.6 43.0 31.3 7.5 16.3 2.6 32.4 5.0 39.4 12.6 18.9 23.3 22.1 9.2 59.1 2.7 5.7 39.7 1.8 50.1 6.0 11.8 21.8 63.0 0.0 1.4 0.7 9.0 8.7 4.6 8.8 3.7 2.0 45.9 13.4 19.6 11.7 17.8 83.9 11.7 10.7 38.0 100.4 43.5 2.5 15.0 26.3 4.2 17.9 81.6 124.2 2.5 2.6 6.4 10.7 8.7 78.9 45.0 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CEP131 "AZ1, AZI1, KIAA1118" ENSG00000141577 "Centrosomal protein 131" Q9UPN4 17 81189593-81222999 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Differentiation, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024019 Approved Supported "Microtubules,Cytokinetic bridge,Centriolar satellite" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" Microtubules "Cytokinetic bridge, Centriolar satellite" "HPA024019: AB_1845227" "unprognostic (1.56e-2)" "unprognostic (1.09e-2)" "unprognostic (2.41e-1)" "unprognostic (2.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (9.68e-5)" "unprognostic (3.43e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.33e-3)" "unprognostic (7.04e-2)" "unprognostic (8.82e-3)" "unprognostic (1.36e-2)" "unprognostic (8.48e-2)" "unprognostic (2.66e-1)" "unprognostic (7.32e-3)" 9.1 8.6 6.7 5.2 6.4 10.2 10.3 7.8 10.0 14.7 7.5 9.8 4.6 11.4 0.9 9.1 11.5 2.0 16.8 6.5 5.8 11.7 6.8 10.7 7.9 6.8 6.2 12.8 10.1 2.2 15.4 4.1 6.2 12.0 0.8 1.8 9.3 2.1 11.1 10.5 10.3 1.6 5.7 19.0 9.9 28.2 6.7 3.5 10.3 2.0 2.2 10.4 10.7 6.8 21.1 20.0 10.6 19.4 1.7 2.7 33.6 14.4 2.5 10.3 7.9 23.8 10.5 14.8 8.0 3.5 6.3 14.9 3.1 7.0 2.5 6.2 26.8 14.3 32.7 41.3 2.9 12.5 30.6 2.3 4.6 7.5 2.1 3.3 7.3 15.6 10.6 8.5 2.7 23.5 29.0 24.3 9.5 6.1 17.7 29.0 12.1 6.1 3.9 18.4 24.2 27.2 18.5 11.4 18.0 3.9 17.2 12.3 10.0 18.6 32.1 16.7 19.2 22.0 4.0 11.3 9.6 10.7 13.5 2.1 0.8 0.5 1.2 2.3 0.3 2.9 0.7 1.1 1.8 1.7 1.1 0.8 1.3 1.0 4.6 2.0 0.1 0.8 6.7 6.4 7.8 10.0 6.5 5.8 6.8 6.2 6.2 5.7 6.7 6.8 6.5 0.0 4.4 5.5 6.6 0.0 3.4 0.0 3.4 5.8 3.3 4.4 13.4 2.8 1.3 3.7 6.2 8.7 4.8 5.6 0.0 4.5 14.0 8.4 3.5 6.0 6.7 5.7 2.1 3.7 7.2 6.9 6.6 2.8 15.9 9.3 2.5 1.7 5.2 5.0 2.9 5.1 0.0 1.9 0.0 17.9 9.6 3.6 0.0 1.0 1.3 6.0 7.2 2.5 2.8 5.2 0.8 3.0 4.4 1.2 1.8 1.4 3.6 6.9 0.0 4.3 5.7 14.7 20.5 3.7 0.0 6.0 3.5 8.4 7.9 2.7 CEP162 "C6orf84, KIAA1009, QN1" ENSG00000135315 "Centrosomal protein 162" Q5TB80 6 84124241-84227643 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.3;Oligodendrocytes: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030170, HPA030171, HPA030172, HPA030173" Supported Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA030170: AB_10611113, HPA030171: AB_10601567, HPA030172: AB_10602414, HPA030173: AB_10602206" "unprognostic (1.75e-1)" "unprognostic (1.46e-2)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.95e-4)" "unprognostic (1.03e-1)" "unprognostic (6.73e-2)" "unprognostic (1.21e-3)" "unprognostic (1.57e-3)" "unprognostic (3.98e-2)" "unprognostic (2.87e-3)" "unprognostic (3.27e-2)" "unprognostic (6.32e-2)" "unprognostic (3.58e-1)" "unprognostic (1.44e-3)" 2.0 1.5 1.1 2.3 1.9 2.4 2.6 1.8 1.6 2.4 3.2 1.9 1.2 3.7 2.2 1.8 3.7 2.8 1.6 0.8 1.3 2.5 1.4 2.7 2.2 1.4 1.6 4.1 2.1 4.2 1.2 2.5 1.5 2.4 2.6 2.8 1.9 2.3 1.0 2.3 1.7 2.6 1.3 2.3 2.7 8.6 1.6 3.9 3.5 1.6 2.3 2.1 1.4 3.0 2.5 1.1 7.1 7.8 4.2 6.1 4.6 2.8 2.7 3.9 4.6 3.2 3.4 2.7 2.6 2.2 6.7 3.8 4.2 2.6 6.2 7.0 2.8 5.0 5.1 2.4 2.1 5.5 4.6 2.9 1.9 3.9 1.5 5.0 4.4 3.7 10.2 3.1 2.8 1.3 1.4 3.3 4.8 1.7 1.6 7.6 9.3 1.5 2.9 2.3 4.6 5.7 2.0 1.1 2.1 5.1 2.5 3.7 3.5 3.8 3.4 3.4 3.1 2.3 3.3 1.6 2.4 2.9 4.8 0.0 0.2 0.3 0.4 0.2 0.5 0.5 0.3 0.3 0.1 0.3 0.2 0.4 0.5 0.0 0.2 0.4 0.0 0.2 1.1 1.9 1.8 1.6 0.8 1.3 1.4 1.6 1.5 1.3 1.6 3.0 13.6 32.1 17.6 42.7 9.6 0.0 6.7 0.0 4.6 5.9 6.1 7.1 11.2 4.3 6.8 9.2 12.5 6.5 7.0 7.0 5.9 12.6 141.3 43.2 18.3 11.3 11.4 10.8 35.0 7.1 5.9 13.3 8.6 11.3 18.3 18.0 7.9 4.2 5.5 28.6 29.2 4.7 0.0 7.9 0.0 57.9 11.8 9.9 0.0 36.5 7.6 9.2 6.2 54.3 64.0 6.8 12.7 12.0 3.7 2.5 5.6 6.8 39.4 14.3 13.1 13.8 10.9 58.7 20.0 3.6 0.0 3.8 8.5 13.4 5.0 4.1 CEP170B "Cep170R, FAM68C, KIAA0284" ENSG00000099814 "Centrosomal protein 170B" Q9Y4F5 14 104865268-104896770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 229.4;Distal enterocytes: 81.2;Rod photoreceptor cells: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000871, HPA059017" Enhanced Approved Microtubules,Centrosome,Cytosol NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Microtubules, Centrosome" "HPA000871: AB_2666124, HPA059017: AB_2683883" "unprognostic (1.09e-1)" "unprognostic (1.60e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (2.38e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (4.96e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (4.41e-4)" "prognostic favorable (3.26e-4)" "unprognostic (1.62e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (1.17e-2)" 13.0 12.8 13.0 4.9 14.1 0.2 13.2 0.0 27.6 11.9 0.0 27.8 17.9 14.8 2.6 31.3 14.7 6.0 9.9 16.6 1.7 29.2 20.2 14.9 0.8 12.3 4.4 6.3 27.7 6.1 21.1 2.7 10.6 19.5 5.7 10.2 18.5 7.7 6.5 36.2 21.1 4.1 0.0 4.5 24.3 15.4 5.1 1.0 20.7 1.4 1.9 16.1 16.4 10.3 23.4 19.1 1.4 17.8 7.4 5.3 41.3 18.0 7.0 8.9 5.9 20.3 14.0 0.0 21.5 13.8 6.1 50.7 4.2 21.1 2.3 8.6 8.8 0.0 22.9 13.4 14.9 0.1 18.2 5.2 26.2 9.3 13.5 7.0 9.0 0.1 6.0 0.2 7.7 49.4 0.1 0.3 5.9 33.2 16.3 7.7 0.1 5.6 8.9 39.1 4.8 5.0 26.7 15.5 24.2 3.0 27.1 3.4 20.0 14.0 15.3 39.0 12.3 0.8 0.1 0.1 11.1 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 14.1 0.0 27.6 16.6 1.7 12.3 4.4 10.6 0.0 5.1 10.3 1.7 9.6 15.3 5.2 0.8 23.8 12.6 12.8 10.2 18.0 15.2 11.4 3.7 22.8 10.0 18.4 229.4 3.6 0.2 81.2 1.9 12.2 0.8 16.2 6.3 4.4 22.1 0.0 17.7 24.0 7.6 5.4 48.4 18.2 5.7 5.7 8.6 12.8 1.4 40.4 14.9 41.0 8.2 0.8 5.2 1.7 3.7 1.3 8.8 2.8 1.0 11.1 0.0 5.5 5.9 31.8 42.9 8.6 0.7 30.3 27.5 5.0 20.1 112.6 6.6 6.8 7.8 1.7 5.2 13.9 24.6 6.7 1.9 0.0 35.6 24.5 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CEP70 "BITE, FLJ13036" ENSG00000114107 "Centrosomal protein 70" Q8NHQ1 3 138494344-138594538 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 222.5;Late spermatids: 299.3;Spermatocytes: 163.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 2.8;MAIT T-cell: 3.3;memory B-cell: 1.7;memory CD4 T-cell: 2.1;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.1;naive CD8 T-cell: 4.0;NK-cell: 2.3;T-reg: 1.3" "Group enriched" "Detected in many" 10 "B-cells: 1.7;NK-cells: 2.3;T-cells: 4.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036941, HPA036942" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" Centrosome "HPA036941: AB_10670567, HPA036942: AB_10670957" "unprognostic (1.61e-1)" "prognostic favorable (2.93e-4)" "unprognostic (2.27e-2)" "unprognostic (3.59e-2)" "unprognostic (3.31e-2)" "unprognostic (3.44e-2)" "unprognostic (1.95e-2)" "unprognostic (9.92e-3)" "unprognostic (9.04e-2)" "unprognostic (4.25e-2)" "unprognostic (5.01e-3)" "prognostic unfavorable (9.60e-5)" "unprognostic (8.90e-3)" "unprognostic (8.07e-3)" "unprognostic (1.46e-1)" "unprognostic (8.71e-3)" "unprognostic (6.43e-2)" 7.5 12.0 20.1 6.3 20.9 5.9 13.3 24.1 22.3 30.6 16.2 17.6 56.2 20.9 21.6 12.0 30.6 13.1 15.8 18.1 25.4 21.4 29.4 14.7 5.5 22.1 21.8 18.5 24.1 21.8 15.6 3.9 21.8 21.0 18.1 35.8 8.7 21.7 18.0 6.8 19.0 11.7 20.5 6.1 13.1 69.0 23.9 42.4 39.2 20.8 6.9 12.1 11.7 22.7 53.7 11.1 25.3 30.8 15.2 16.9 23.5 10.4 19.4 14.0 20.5 15.5 27.9 12.5 24.0 19.2 53.1 23.0 23.2 20.6 31.1 22.2 15.3 35.7 26.0 20.1 24.2 1.6 12.5 92.3 11.7 10.6 26.2 37.0 20.5 40.1 26.6 40.5 23.1 20.1 38.4 2.1 15.0 13.9 24.6 41.7 32.9 32.3 26.9 23.8 30.7 19.8 54.5 12.7 60.8 28.4 64.3 17.7 12.1 10.3 19.0 21.3 12.9 37.2 22.1 42.6 22.9 3.3 35.7 0.2 0.0 0.1 2.8 0.1 3.3 1.7 2.1 2.3 0.0 1.4 4.1 4.0 0.2 2.3 0.0 0.1 1.3 1.2 20.1 20.9 24.1 22.3 18.1 25.4 22.1 21.8 21.8 20.5 23.9 22.7 7.0 32.1 69.3 44.1 4.8 9.7 46.3 14.0 22.2 15.8 11.8 9.8 34.3 22.8 27.4 20.2 35.5 8.1 4.6 10.5 72.4 24.9 222.5 114.0 14.9 7.7 15.6 13.7 51.8 17.6 4.4 11.8 16.3 52.6 20.8 21.9 6.1 14.7 2.4 21.9 48.5 11.1 8.2 0.3 3.0 299.3 9.9 2.3 10.6 19.7 0.6 26.4 2.1 60.8 30.5 12.7 8.1 12.8 9.2 29.5 3.3 21.1 34.5 31.1 6.6 17.5 12.4 163.6 9.5 18.6 8.1 9.6 8.9 9.5 23.9 28.6 CEP72 "FLJ10565, KIAA1519" ENSG00000112877 "Centrosomal protein 72" Q9P209 5 612340-667168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.3" "Cell type enriched" "Detected in many" 4 "Melanocytes: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 4.5" "Group enriched" "Detected in many" 4 "B-cells: 1.6;NK-cells: 4.5;T-cells: 1.7" "Cell line enhanced" "Detected in many" "HDLM-2: 46.0;HeLa: 40.0" "Region enriched" "Detected in many" 8 "cerebellum: 14.1" "Not detected" "Not detected" "HPA058235, HPA074879" Approved Approved Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Centrosome "Nucleoplasm, Mitochondria" "HPA058235: AB_2683649, HPA074879: AB_2686720" "unprognostic (2.06e-1)" "unprognostic (3.15e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (8.50e-2)" "unprognostic (9.74e-2)" "unprognostic (2.94e-3)" "unprognostic (3.20e-1)" "unprognostic (1.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.38e-2)" "unprognostic (4.38e-3)" "unprognostic (1.81e-3)" "unprognostic (3.60e-2)" "unprognostic (2.93e-1)" "unprognostic (4.68e-2)" "unprognostic (1.24e-2)" 1.1 0.9 1.3 1.9 1.2 3.1 1.4 1.5 1.3 1.6 0.8 1.2 1.4 1.3 1.0 2.2 1.6 1.5 0.9 1.4 0.6 1.4 2.1 1.4 2.7 0.7 0.8 2.8 1.9 1.2 1.5 0.7 0.8 1.3 0.8 1.1 1.7 0.8 0.7 2.4 1.6 0.9 0.6 1.8 1.8 7.3 0.9 3.0 1.8 0.6 1.4 1.2 1.7 1.8 7.5 11.9 10.6 15.0 0.9 1.0 19.1 3.2 1.4 7.1 6.2 10.8 11.2 8.8 8.2 1.4 13.2 7.1 7.5 5.4 2.8 46.0 11.8 9.7 40.0 4.3 1.3 11.3 6.3 1.1 2.3 6.1 4.1 1.4 2.8 17.0 10.1 10.1 3.5 5.7 17.1 9.8 7.0 6.4 11.1 12.8 6.1 12.2 2.3 5.8 8.1 6.2 23.3 7.6 2.0 3.3 7.6 8.7 0.9 6.8 9.9 6.5 4.6 6.3 6.4 8.8 4.2 15.7 7.3 0.0 0.3 0.3 1.3 0.1 1.7 1.4 1.1 1.2 0.1 1.6 1.6 1.6 0.0 4.5 0.6 0.4 1.5 0.8 1.3 1.2 1.5 1.3 1.4 0.6 0.7 0.8 0.8 0.6 0.9 1.8 0.7 3.2 1.5 1.3 2.9 5.7 0.9 2.4 0.6 2.5 1.1 1.8 2.2 2.8 1.0 0.0 0.0 1.2 1.1 1.1 0.0 2.5 4.0 2.4 1.5 1.1 0.0 4.2 2.5 0.9 5.1 1.0 3.6 1.9 0.0 3.8 0.4 1.7 1.4 3.3 1.3 0.7 4.1 0.8 2.9 2.2 1.2 0.7 135.2 1.0 1.4 0.9 2.1 2.0 3.9 2.3 0.5 2.6 4.7 1.1 0.1 0.5 3.4 2.0 0.0 1.3 1.1 30.7 10.1 2.8 3.7 1.6 1.9 0.9 1.3 2.5 CEP85 "CCDC21, DKFZP434L0117" ENSG00000130695 "Centrosomal protein 85" Q6P2H3 1 26234200-26278808 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.9;tongue: 65.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.0;Oligodendrocytes: 28.8;Spermatocytes: 40.9;Spermatogonia: 34.2;Syncytiotrophoblasts: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028252 Approved Approved "Nucleoli,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Golgi apparatus" "Centrosome, Cytosol" "HPA028252: AB_1846142" "unprognostic (1.08e-1)" "unprognostic (2.59e-2)" "unprognostic (1.74e-2)" "unprognostic (4.16e-2)" "unprognostic (2.66e-1)" "unprognostic (5.30e-3)" "prognostic unfavorable (4.39e-6)" "unprognostic (3.72e-2)" "unprognostic (5.30e-2)" "unprognostic (8.24e-2)" "unprognostic (9.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (7.33e-3)" "unprognostic (5.41e-2)" "unprognostic (1.02e-2)" "unprognostic (2.60e-2)" 2.8 3.5 3.9 5.3 8.3 20.8 3.8 5.6 6.7 4.1 3.7 5.4 3.4 3.2 3.2 8.6 2.7 2.7 25.5 4.3 5.9 6.0 5.8 4.7 6.9 7.1 6.8 3.3 5.0 8.8 6.1 3.2 8.9 2.9 6.0 14.1 5.3 2.4 132.9 9.8 5.2 3.7 3.7 6.3 4.7 31.1 7.1 13.6 7.8 65.9 7.8 3.2 6.2 14.3 29.6 12.5 30.2 22.6 7.3 8.9 52.5 18.8 11.5 31.9 28.5 17.4 28.2 34.3 20.1 9.2 14.6 25.5 41.0 14.4 29.9 23.5 20.9 49.7 31.9 19.4 6.6 46.2 43.8 3.8 13.7 24.9 16.4 12.8 14.5 47.7 57.4 39.9 19.2 9.8 38.7 35.2 23.0 17.4 20.8 39.8 31.3 29.7 10.4 5.5 41.4 16.7 24.5 19.8 15.7 21.5 14.5 26.4 14.3 17.1 26.7 19.3 24.7 30.0 48.4 38.9 9.8 65.2 27.5 5.0 6.4 19.2 3.5 6.1 2.8 2.6 2.6 2.7 4.9 1.8 2.2 3.5 0.6 2.3 7.4 2.1 3.6 3.6 3.9 8.3 5.6 6.7 4.3 5.9 7.1 6.8 8.9 3.7 7.1 14.3 1.0 0.0 2.2 3.6 2.7 6.9 4.0 2.5 6.2 11.2 3.7 2.9 29.0 1.5 3.7 5.5 12.5 3.4 5.1 6.9 7.9 1.7 1.0 3.4 2.3 2.0 1.8 16.8 12.8 1.3 3.9 2.3 3.6 4.9 2.5 9.1 1.4 3.1 4.8 0.0 9.9 3.7 2.0 5.0 3.7 2.9 1.5 4.3 1.8 4.7 4.0 1.8 2.1 3.0 28.8 2.7 3.4 0.4 4.4 2.5 2.3 1.1 2.0 11.1 0.0 2.4 2.3 40.9 34.2 8.6 6.1 41.7 3.4 2.3 4.5 4.5 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 703.3;liver: 345.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 794.4;Hepatocytes: 518.5;Paneth cells: 519.2;Proximal enterocytes: 2529.8;Undifferentiated cells: 499.5" "Cancer enhanced" "Detected in all" "liver cancer: 104.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA018897, HPA074629" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 6400000 "Cluster 44: Non-specific - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558, HPA074629: " "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 18.8 38.1 21.2 18.1 20.6 6.3 13.5 24.1 23.0 22.0 25.6 191.2 703.3 14.6 14.4 132.7 17.9 19.5 51.4 22.1 20.6 96.5 345.7 15.6 11.9 20.8 20.8 17.0 14.4 38.0 15.7 10.1 20.6 16.7 178.8 16.2 32.9 15.0 33.8 32.7 576.5 19.7 20.0 12.4 41.6 9.3 20.9 13.1 27.9 14.3 20.8 13.7 33.5 20.5 11.6 16.6 18.4 25.9 19.5 17.9 14.5 15.9 25.8 17.6 22.1 17.3 23.5 15.7 14.3 20.9 13.3 35.4 14.2 39.8 15.3 10.7 18.9 14.4 9.6 44.2 26.3 21.6 26.3 25.4 82.5 26.0 46.7 24.6 14.1 11.3 22.2 10.9 35.7 9.1 17.7 21.4 10.8 16.3 18.8 20.9 19.1 19.8 60.7 18.6 11.6 16.0 50.9 12.6 14.5 8.1 21.0 26.5 17.5 22.4 12.6 15.3 11.1 23.3 24.0 18.4 36.7 17.3 17.4 4.1 5.4 1.6 5.1 3.8 4.5 3.0 4.1 5.8 4.5 3.1 4.8 4.5 1.6 4.3 4.1 4.3 3.2 3.1 21.2 20.6 24.1 23.0 22.1 20.6 20.8 20.8 20.6 20.0 20.9 20.5 13.2 32.1 24.6 8.8 18.8 19.5 13.5 32.8 39.3 31.2 12.4 18.3 33.6 115.8 19.8 53.3 20.9 16.1 12.9 794.4 37.2 24.6 2.1 26.9 15.0 14.1 24.1 7.8 7.0 33.8 5.7 15.3 60.6 33.7 27.3 80.7 28.5 518.5 19.6 28.6 9.7 196.0 18.3 37.0 9.6 2.3 18.6 15.3 10.6 10.3 19.5 19.0 21.6 8.0 5.9 51.8 519.2 18.0 8.5 19.1 2529.8 176.0 85.4 24.2 32.9 19.5 15.2 47.2 19.7 116.1 20.5 13.5 13.0 22.1 499.5 16.7 CETN1 "CEN1, CETN" ENSG00000177143 "Centrin 1" Q12798 18 580380-582114 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1084 "testis: 134.3" "Group enriched" "Detected in some" 34 "Early spermatids: 930.9;Late spermatids: 435.6;Spermatocytes: 675.9" "Cancer enriched" "Detected in single" 10 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001470, HPA028956, CAB037244, HPA069157" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centriolar satellite, Cytosol" "CAB037244: AB_476871, HPA001470: , HPA028956: AB_10601798, HPA069157: " "unprognostic (1.51e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 930.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 435.6 12.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 675.9 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CETN2 "CALT, CEN2" ENSG00000147400 "Centrin 2" P41208 X 152826994-152830757 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 243.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 639.9;Proximal tubular cells: 345.8;Respiratory ciliated cells: 1116.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001470, HPA028956" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Centriolar satellite, Cytosol" "HPA001470: , HPA028956: AB_10601798" "unprognostic (3.32e-1)" "prognostic favorable (7.54e-6)" "unprognostic (7.73e-2)" "unprognostic (2.14e-2)" "unprognostic (2.14e-1)" "unprognostic (5.73e-3)" "unprognostic (9.58e-3)" "unprognostic (1.30e-1)" "unprognostic (1.28e-1)" "prognostic favorable (9.97e-4)" "unprognostic (5.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.32e-3)" "unprognostic (5.90e-2)" "unprognostic (1.25e-2)" "unprognostic (1.34e-1)" "unprognostic (2.20e-1)" 30.2 41.0 61.8 19.8 62.3 26.2 40.3 58.3 80.4 64.6 90.5 54.6 15.2 57.6 116.2 37.2 243.6 31.7 34.6 60.6 65.8 74.7 31.5 39.8 16.0 68.0 75.8 57.2 24.0 55.7 73.9 21.4 70.4 50.3 25.8 40.1 24.4 77.7 19.6 23.8 21.6 54.8 67.4 16.8 29.3 23.3 64.8 21.0 67.2 20.2 21.9 37.3 36.1 67.1 145.2 65.0 78.8 59.6 102.5 110.5 31.4 61.6 73.8 79.9 60.9 29.5 75.8 51.6 157.8 83.1 128.8 55.3 55.3 76.7 94.1 23.2 40.0 11.5 32.1 86.6 38.5 48.7 12.5 67.0 99.2 74.1 39.1 95.4 64.0 40.3 31.0 20.9 78.3 67.9 36.4 53.0 27.5 119.9 82.6 31.9 57.2 53.2 146.9 35.4 38.5 50.0 41.2 42.2 38.2 70.8 45.4 37.2 59.8 56.0 44.9 111.9 69.9 20.9 29.7 81.0 118.3 28.9 28.0 19.9 11.4 35.9 11.7 13.6 14.2 11.9 11.5 13.1 13.5 9.7 12.2 12.5 10.9 12.3 13.7 20.0 10.5 11.8 61.8 62.3 58.3 80.4 60.6 65.8 68.0 75.8 70.4 67.4 64.8 67.1 21.6 51.3 35.7 3.9 19.2 22.6 52.4 201.6 21.6 13.6 46.1 47.6 37.1 64.3 155.8 169.2 6.2 66.6 16.2 13.8 238.7 100.3 60.1 639.9 65.4 29.6 37.1 33.2 4.2 41.1 69.8 42.9 12.2 68.7 24.6 41.0 44.3 96.5 50.0 13.5 3.5 31.7 150.5 23.7 21.3 72.5 67.7 27.3 37.4 1.9 27.8 104.4 20.6 0.5 2.5 39.6 16.0 111.7 16.6 29.3 15.4 345.8 1116.5 29.4 19.7 22.7 64.2 76.5 70.4 33.7 30.5 41.5 19.7 51.8 29.2 42.4 CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1342.4;Late spermatids: 262.5;Spermatocytes: 346.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies" Cytosol "HPA008994: AB_2275429, HPA017061: AB_1846129" "unprognostic (8.11e-2)" "unprognostic (3.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.36e-2)" "unprognostic (7.98e-2)" "unprognostic (3.68e-1)" "unprognostic (4.65e-3)" "unprognostic (7.79e-2)" "unprognostic (1.51e-2)" "unprognostic (1.58e-2)" "unprognostic (3.66e-3)" "unprognostic (7.63e-2)" "unprognostic (8.57e-3)" "unprognostic (4.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-3)" "unprognostic (2.96e-1)" 39.1 42.7 72.7 20.2 74.8 16.5 48.9 61.8 98.8 49.8 82.8 52.3 15.1 47.1 77.0 21.9 62.3 40.9 35.7 75.0 78.5 63.2 17.7 33.9 21.7 71.8 70.4 58.9 33.6 78.0 106.7 20.6 72.1 41.6 23.2 124.3 28.7 45.0 19.2 18.8 25.2 37.4 65.9 18.2 42.1 145.2 73.6 22.8 78.0 27.1 19.7 40.7 33.6 70.1 59.5 47.3 50.2 66.3 64.4 119.4 30.4 36.6 73.4 54.9 46.6 34.6 21.2 21.3 82.3 48.9 81.9 38.4 39.3 51.4 67.7 51.9 76.2 31.0 43.9 38.1 70.0 59.4 38.4 58.1 82.7 74.0 92.1 146.8 58.9 42.5 40.1 18.2 66.1 44.4 35.7 67.5 25.2 38.7 44.8 27.2 59.7 21.7 112.1 33.7 74.1 36.6 49.4 25.6 68.5 26.2 42.1 19.7 32.5 57.6 33.7 58.5 50.8 29.9 14.2 7.3 94.0 26.7 26.8 15.5 4.3 13.6 18.3 5.0 35.4 16.9 50.6 29.6 5.8 11.7 41.1 26.0 5.2 12.3 6.4 13.5 30.5 15.9 72.7 74.8 61.8 98.8 75.0 78.5 71.8 70.4 72.1 65.9 73.6 70.1 51.3 48.1 30.6 15.7 14.5 0.0 52.6 0.0 22.2 39.6 48.7 77.2 37.9 38.6 27.2 35.0 8.4 14.3 14.8 6.4 92.0 61.9 1342.4 184.4 51.8 42.9 17.0 21.0 51.6 60.7 27.0 44.7 21.9 36.3 39.1 27.1 42.1 10.7 23.6 23.5 41.1 12.2 0.0 8.7 0.0 262.5 75.2 12.8 0.0 14.0 16.9 145.0 16.5 21.6 13.3 37.0 11.5 67.7 11.4 41.3 7.6 146.9 99.1 92.4 59.2 43.0 43.4 346.0 29.8 16.1 0.0 7.8 24.7 36.0 9.9 35.6 CFAP410 "A2, C21orf2, LRRC76, YF5" ENSG00000160226 "Cilia and flagella associated protein 410" O43822 21 44328944-44339402 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, DNA damage" "Ciliopathy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 30.8;Extravillous trophoblasts: 15.7;Hofbauer cells: 35.5;Syncytiotrophoblasts: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030283, HPA030284, CAB034126, CAB034128" Supported Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Vesicles, Cytosol" "CAB034126: AB_1564257, CAB034128: AB_1564259, HPA030283: , HPA030284: AB_10602700" "unprognostic (1.84e-1)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.36e-1)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (9.73e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.49e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.98e-1)" "unprognostic (2.79e-1)" "unprognostic (1.32e-2)" "unprognostic (1.06e-1)" 19.8 22.2 14.5 5.1 14.6 11.4 19.5 13.8 18.6 22.9 12.7 21.1 6.5 23.4 2.3 12.5 26.3 3.8 19.9 14.9 14.5 26.0 26.8 18.5 6.6 16.5 16.8 22.3 24.0 7.5 34.4 3.3 14.5 26.3 1.4 10.0 18.6 5.0 16.1 17.9 19.2 2.4 13.9 20.9 20.7 30.9 18.5 4.2 32.8 4.9 2.3 19.2 14.8 16.2 12.9 5.2 4.9 6.3 3.2 2.0 19.3 6.4 3.7 2.5 1.3 9.4 3.7 9.1 12.5 2.2 5.1 6.0 0.9 1.2 0.6 14.2 12.9 9.5 4.3 11.2 4.1 10.2 9.8 2.9 2.2 1.0 2.2 4.4 1.6 6.7 11.6 15.1 1.6 15.5 11.2 25.0 12.2 6.4 7.8 28.6 6.3 20.3 2.9 18.0 12.9 12.2 8.9 2.1 11.0 2.9 9.3 22.0 7.5 5.4 6.9 5.8 4.9 25.1 14.2 6.4 13.2 20.4 9.9 1.7 10.2 1.6 9.4 12.6 11.3 16.6 10.0 13.2 10.5 11.6 11.3 11.1 1.3 17.3 9.5 31.3 6.1 7.6 14.5 14.6 13.8 18.6 14.9 14.5 16.5 16.8 14.5 13.9 18.5 16.2 5.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 30.8 6.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 15.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 32.7 1.1 0.0 0.0 0.0 CFAP58 "bA554P13.1, C10orf80, CCDC147, FLJ35908" ENSG00000120051 "Cilia and flagella associated protein 58" Q5T655 10 104353833-104455102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.4;testis: 13.4" "Group enriched" "Detected in some" 4 "Early spermatids: 73.3;Endometrial ciliated cells: 25.1;Late spermatids: 58.9;Respiratory ciliated cells: 56.9;Spermatocytes: 34.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.1" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;U-2 OS: 6.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.9" "HPA036555, HPA071938" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Plasma membrane, Cytosol" "HPA036555: AB_10673622, HPA071938: " "unprognostic (5.32e-1)" "unprognostic (2.59e-1)" "unprognostic (6.26e-2)" "unprognostic (1.57e-3)" "unprognostic (5.41e-3)" "unprognostic (1.01e-1)" "unprognostic (9.62e-2)" "unprognostic (5.64e-2)" "unprognostic (3.11e-1)" "unprognostic (2.18e-1)" "unprognostic (8.93e-2)" "unprognostic (3.15e-1)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" "unprognostic (6.81e-2)" "unprognostic (4.19e-2)" "unprognostic (1.59e-1)" 0.4 0.6 1.0 0.5 1.3 0.4 0.4 0.4 0.7 2.2 2.4 0.5 0.1 1.8 0.2 0.2 8.4 0.2 2.5 0.8 1.2 0.7 0.1 1.3 0.3 2.9 3.7 0.5 0.3 0.7 1.5 0.4 2.2 0.5 0.0 0.6 0.2 0.4 1.3 0.3 0.2 0.6 2.0 0.3 0.3 13.4 1.0 0.1 0.8 0.8 0.4 0.3 0.6 1.1 0.1 0.0 0.7 0.1 0.1 0.3 0.1 1.0 3.1 0.6 1.6 0.0 0.0 2.4 0.2 0.4 1.7 0.2 0.0 0.2 1.8 0.3 0.1 0.5 0.9 0.0 0.3 0.3 0.4 0.3 1.3 0.5 1.6 1.3 1.0 0.1 0.7 0.7 0.8 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.2 0.3 0.3 0.0 0.4 0.2 0.0 0.1 0.5 0.7 0.1 0.4 2.0 0.6 6.5 0.3 1.8 0.2 0.0 0.1 0.7 0.8 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.4 0.7 0.8 1.2 2.9 3.7 2.2 2.0 1.0 1.1 0.4 0.0 0.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 10.0 0.0 9.3 0.0 0.0 0.1 0.1 0.0 0.0 0.6 73.3 25.1 0.3 0.4 0.0 0.0 4.0 0.2 0.4 0.7 0.0 0.4 0.0 0.3 1.8 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 58.9 0.6 0.2 0.0 1.9 0.1 0.7 1.0 1.0 0.0 0.3 0.0 1.2 0.0 0.2 0.0 0.0 56.9 0.3 0.0 0.8 1.0 34.4 4.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149858-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 21.6;choroid plexus: 28.1;fallopian tube: 42.2" "Cell type enriched" "Detected in some" 4 "Endometrial ciliated cells: 110.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.3;REH: 2.2;T-47d: 2.5;U-698: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: AB_2680434" "unprognostic (2.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.90e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.18e-3)" "unprognostic (6.49e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.43e-2)" "unprognostic (1.62e-4)" "unprognostic (2.03e-4)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.55e-2)" 0.2 0.4 3.2 0.4 2.8 2.1 0.3 1.1 1.0 3.8 28.1 0.3 0.3 0.5 0.3 0.5 42.2 0.2 0.2 5.5 5.8 1.7 0.5 7.1 0.7 17.9 21.6 0.4 0.4 0.1 1.2 0.0 11.3 0.6 0.0 0.2 2.3 0.7 0.3 4.7 0.5 0.0 15.0 0.6 4.0 0.5 4.6 0.0 0.8 0.0 1.2 0.2 0.2 3.4 0.2 0.0 0.2 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 2.0 4.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.2 1.7 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.7 0.2 0.7 0.3 0.8 0.1 2.2 0.0 0.3 0.5 0.5 0.4 0.1 0.0 0.6 0.0 0.2 2.5 0.0 0.1 0.1 0.7 0.2 0.1 0.4 0.1 9.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.8 1.1 1.0 5.5 5.8 17.9 21.6 11.3 15.0 4.6 3.4 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 6.2 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.4 110.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.6 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 23.3 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.1 0.2 CFAP99 ENSG00000206113 "Cilia and flagella associated protein 99" 4 2418974-2462942 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;choroid plexus: 5.8;fallopian tube: 3.9;retina: 1.5;testis: 5.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Early spermatids: 11.6;Endometrial ciliated cells: 13.6;Late spermatids: 11.2;Rod photoreceptor cells: 5.5;Spermatocytes: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA071642 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA071642: " "unprognostic (7.54e-3)" "unprognostic (6.46e-3)" "unprognostic (1.12e-1)" "unprognostic (2.31e-3)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.89e-1)" "unprognostic (8.14e-2)" "unprognostic (7.93e-5)" "unprognostic (1.15e-1)" "unprognostic (5.97e-3)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (6.94e-2)" "unprognostic (3.49e-1)" 0.0 0.8 0.5 0.0 0.5 0.0 0.0 0.8 0.3 0.2 5.8 0.0 0.0 0.2 0.1 0.0 3.9 0.0 0.0 0.9 0.8 0.2 0.1 0.6 0.0 3.2 4.8 0.0 0.3 0.0 0.8 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 5.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 0.3 0.9 0.8 3.2 4.8 1.8 2.0 1.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.2 0.0 1.8 3.7 4.2 0.0 0.0 0.0 0.0 0.2 11.6 13.6 0.2 0.1 0.0 0.0 1.2 0.6 0.1 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 1.5 2.9 5.5 0.0 0.0 0.0 14.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 372.8;skeletal muscle: 719.9;tongue: 686.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 522.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000000 "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB037078: AB_259128, HPA045599: AB_2679383" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (2.80e-3)" "unprognostic (3.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (1.65e-2)" "unprognostic (3.13e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (2.16e-5)" 48.7 52.5 71.7 28.6 98.7 18.1 24.6 90.3 116.1 39.8 53.9 92.5 14.3 73.4 19.5 69.0 42.6 24.1 372.8 69.4 85.0 31.4 125.9 24.9 10.7 85.7 83.6 41.2 9.4 24.4 10.9 35.3 88.7 75.4 28.1 41.0 17.1 107.3 719.9 8.2 24.0 115.0 74.7 12.7 36.1 21.7 81.2 10.4 29.4 686.4 9.9 56.8 24.3 130.5 87.1 77.7 49.5 32.0 51.1 185.6 27.9 146.6 170.5 145.6 151.4 61.9 38.5 30.6 58.5 245.2 104.9 17.1 107.4 32.5 268.6 4.2 45.0 6.6 87.4 144.5 81.6 8.2 5.3 139.3 12.4 122.2 67.7 96.8 145.9 4.5 9.9 26.8 186.9 25.5 6.3 4.3 16.3 15.4 118.9 5.4 158.1 4.7 55.1 17.7 10.3 41.7 96.6 21.5 51.2 36.2 47.8 7.5 124.6 140.9 93.0 66.1 72.9 34.3 22.8 11.7 51.7 11.4 34.5 1.8 1.0 1.3 1.9 1.0 3.1 4.9 2.2 2.1 1.6 3.0 1.7 1.8 0.3 1.8 0.4 1.6 2.1 0.9 71.7 98.7 90.3 116.1 69.4 85.0 85.7 83.6 88.7 74.7 81.2 130.5 39.6 105.8 41.6 6.2 17.0 20.0 88.6 31.3 23.9 62.8 19.6 16.6 522.2 22.8 26.3 22.0 20.9 32.2 11.5 0.9 60.7 45.2 2.6 40.3 60.5 45.1 9.5 11.4 9.6 39.7 60.5 69.9 6.1 56.2 5.7 25.8 47.2 112.0 15.6 77.4 14.2 2.4 57.0 15.7 14.4 10.1 57.2 10.6 30.2 11.2 5.7 112.9 15.5 8.0 93.8 24.7 4.0 98.6 60.4 84.0 1.0 101.9 24.7 57.8 32.9 83.9 115.8 49.3 51.9 16.1 19.5 21.3 21.1 47.9 4.6 58.5 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CHAMP1 "C13orf8, CAMP, CHAMP, ZNF828" ENSG00000198824 "Chromosome alignment maintaining phosphoprotein 1" Q96JM3 13 114314482-114337626 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006623, HPA008900" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Midbody ring" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA006623: AB_1845548, HPA008900: AB_1845547" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (1.67e-1)" "unprognostic (3.89e-3)" "unprognostic (2.07e-1)" "unprognostic (9.43e-2)" "unprognostic (1.13e-1)" "unprognostic (4.38e-2)" "unprognostic (1.13e-2)" "unprognostic (4.40e-2)" "unprognostic (3.50e-2)" "unprognostic (3.67e-1)" "unprognostic (4.62e-2)" "unprognostic (2.40e-1)" 9.9 7.1 3.4 9.8 3.3 14.2 9.5 6.6 5.2 8.1 3.8 8.7 10.0 8.5 8.0 6.4 9.8 7.6 6.2 3.0 4.3 8.9 15.2 8.9 15.7 2.7 3.4 12.1 15.4 9.3 3.6 9.9 3.4 10.0 9.9 9.1 8.4 9.3 7.9 9.2 8.0 10.1 2.3 9.6 7.7 6.9 2.7 16.5 10.7 9.7 17.3 7.5 4.4 3.1 36.9 15.8 56.6 24.2 20.1 30.9 24.3 38.2 32.0 35.6 39.4 23.5 22.0 75.2 15.1 30.0 22.3 23.0 41.8 30.6 52.7 29.8 50.0 49.7 21.8 20.7 22.5 73.3 28.3 30.4 18.8 27.8 27.3 12.6 17.4 25.8 32.1 20.3 46.1 14.6 48.6 21.4 43.1 45.2 20.2 48.1 26.9 26.0 27.0 22.2 27.5 32.8 22.2 49.2 36.7 39.1 28.2 61.3 19.3 19.5 30.8 20.7 23.6 25.7 27.9 80.4 38.6 42.7 38.1 7.5 3.3 4.4 3.7 4.0 4.6 5.4 3.3 3.7 3.9 5.8 2.6 3.0 0.8 3.5 6.6 12.5 2.4 2.1 3.4 3.3 6.6 5.2 3.0 4.3 2.7 3.4 3.4 2.3 2.7 3.1 11.2 9.6 9.6 3.6 13.9 3.3 6.6 7.6 10.8 12.5 11.3 10.8 5.7 11.5 4.1 12.9 4.2 14.2 18.1 9.3 13.7 11.7 1.0 8.5 14.8 10.9 10.8 24.4 6.1 11.4 18.1 11.5 10.2 8.3 10.1 13.1 13.9 21.6 21.7 15.2 7.8 12.5 6.1 20.7 7.8 1.6 11.8 13.0 12.4 7.5 18.4 8.8 17.5 4.0 8.0 10.9 7.8 11.3 17.6 13.2 12.5 17.0 7.6 10.9 6.6 11.7 10.5 10.6 20.7 13.1 3.8 7.9 11.4 12.4 11.4 3.5 CHCHD1 "C10orf34, FLJ25854" ENSG00000172586 "Coiled-coil-helix-coiled-coil-helix domain containing 1" Q96BP2 10 73782047-73783652 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 561.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039046 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "Nucleoli fibrillar center" "HPA039046: AB_10673234" "unprognostic (4.97e-2)" "unprognostic (1.90e-3)" "unprognostic (2.96e-1)" "unprognostic (1.31e-3)" "unprognostic (1.80e-1)" "unprognostic (9.85e-2)" "unprognostic (1.75e-2)" "unprognostic (3.33e-1)" "unprognostic (1.35e-1)" "unprognostic (2.24e-2)" "unprognostic (4.53e-1)" "unprognostic (1.91e-2)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (5.58e-2)" "prognostic favorable (5.42e-4)" 30.1 53.2 38.7 29.3 39.1 26.7 34.4 40.0 45.1 25.4 41.9 38.1 40.0 25.9 52.0 49.8 25.6 18.5 52.9 38.9 39.6 55.9 54.7 25.6 36.4 38.8 38.5 24.1 31.3 42.8 31.0 29.2 39.2 36.7 29.0 21.9 45.6 21.9 64.2 29.9 35.1 19.1 39.3 40.3 37.6 24.8 39.4 34.6 31.9 50.6 30.8 27.7 30.1 40.1 115.8 87.6 70.8 98.3 57.0 56.6 71.1 58.3 70.7 59.8 80.0 78.6 99.3 56.9 63.3 52.9 60.1 77.9 69.8 79.8 46.9 87.6 132.4 42.7 73.2 119.6 68.6 65.8 65.7 52.3 96.3 51.5 33.0 87.4 83.9 78.8 67.0 61.7 78.3 117.3 82.1 146.5 66.3 109.6 561.7 77.3 53.9 72.6 97.5 63.0 34.2 67.4 36.0 246.2 127.3 56.8 138.0 92.5 47.2 35.7 79.7 60.2 102.4 61.5 70.7 91.2 83.4 133.7 28.5 44.2 51.3 32.5 36.1 54.9 43.9 62.6 43.7 43.5 52.5 50.8 36.1 36.9 21.2 36.6 45.6 75.1 65.2 35.8 38.7 39.1 40.0 45.1 38.9 39.6 38.8 38.5 39.2 39.3 39.4 40.1 45.0 41.7 48.4 5.2 50.7 35.1 34.4 117.2 29.0 27.0 68.7 74.4 77.3 47.1 84.4 60.7 22.9 151.6 49.3 112.1 199.6 80.8 73.3 99.0 64.1 44.5 61.8 61.2 8.6 88.3 166.3 38.2 41.8 75.8 29.8 63.9 51.4 132.5 139.7 20.2 8.0 106.2 122.1 61.2 35.6 16.3 56.5 52.7 40.9 5.6 82.5 76.8 51.5 5.5 9.6 96.4 96.4 55.3 53.3 55.3 101.0 243.3 99.0 35.3 52.6 36.1 52.4 70.1 48.7 71.2 43.5 128.1 41.6 83.9 98.4 54.9 CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884796-7912760 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Supported "Nucleoplasm,Nucleoli,Centriolar satellite" No No "Cluster 27: Non-specific - Gene expression" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA043368: AB_2678448, HPA076524: AB_2686804" "unprognostic (1.77e-2)" "unprognostic (8.01e-2)" "prognostic unfavorable (2.43e-4)" "prognostic favorable (7.68e-5)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.83e-2)" "unprognostic (5.25e-3)" "prognostic favorable (8.36e-4)" "unprognostic (9.11e-2)" "unprognostic (8.31e-2)" "unprognostic (3.98e-2)" "unprognostic (1.50e-1)" "unprognostic (8.90e-3)" "unprognostic (2.20e-3)" 28.2 29.3 19.9 35.0 27.9 42.7 28.4 0.0 39.9 71.6 0.0 55.3 16.7 63.9 31.2 35.1 56.8 27.8 21.2 35.8 7.0 38.3 5.7 32.4 41.3 4.9 2.4 60.0 34.8 44.7 47.7 16.6 1.1 68.7 22.1 19.0 40.3 38.0 8.0 32.7 34.6 45.0 3.1 31.5 36.3 20.9 8.0 58.2 44.9 9.1 36.7 41.2 42.8 21.4 44.9 108.7 61.6 81.2 72.2 60.9 32.8 51.7 66.1 40.8 43.5 21.1 36.7 122.8 38.3 73.0 34.0 59.6 117.7 52.5 53.0 65.5 67.2 62.7 148.5 2.7 38.3 17.8 112.1 79.2 27.5 55.4 36.9 108.7 76.9 54.1 41.5 2.0 38.8 42.6 48.2 19.6 9.8 45.3 40.3 137.8 82.1 19.3 40.0 107.7 41.9 56.3 126.4 47.9 24.6 16.9 55.7 27.1 99.7 89.4 68.8 22.3 72.5 8.8 1.6 68.3 46.1 47.4 77.6 1.7 2.6 3.3 4.1 1.4 3.6 1.1 4.2 4.0 1.3 1.2 4.6 3.1 2.8 3.2 3.2 3.0 2.5 2.5 19.9 27.9 0.0 39.9 35.8 7.0 4.9 2.4 1.1 3.1 8.0 21.4 20.9 32.1 63.2 10.4 19.6 36.6 47.6 21.1 65.4 60.7 43.8 34.2 14.3 17.2 35.2 80.9 8.4 16.8 57.3 39.8 17.6 22.9 11.3 48.6 51.9 29.4 56.8 19.1 20.6 23.4 20.5 39.9 31.1 70.7 39.9 59.7 22.9 2.7 9.0 45.4 25.2 17.0 12.2 24.7 34.7 18.5 44.4 26.7 8.8 6.5 43.7 12.4 59.8 12.1 2.5 20.9 10.8 57.2 17.4 55.5 10.9 9.7 24.8 17.3 26.3 31.8 43.5 25.5 46.8 52.8 20.5 16.4 62.9 52.0 30.3 60.3 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CHIC1 BRX ENSG00000204116 "Cysteine rich hydrophobic domain 1" Q5VXU3 X 73563200-73687102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 47.0;Excitatory neurons: 62.7;Inhibitory neurons: 59.6;Microglial cells: 29.0;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA052062" Uncertain Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles, Vesicles" Cytosol "HPA026782: AB_1846654, HPA052062: AB_2681714" "unprognostic (9.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.10e-2)" "unprognostic (9.95e-2)" "unprognostic (6.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (2.43e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.65e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-2)" "unprognostic (2.19e-1)" "unprognostic (3.51e-1)" "unprognostic (2.76e-2)" 2.9 7.0 4.4 3.0 4.8 0.6 3.7 4.6 8.5 7.1 2.4 5.2 2.3 5.6 3.8 2.4 4.2 4.6 5.4 5.7 6.1 6.3 1.5 2.7 3.9 5.9 4.6 5.7 2.2 5.9 5.6 2.1 6.0 4.8 4.2 5.4 2.8 5.1 2.6 3.0 3.4 5.4 4.9 4.1 2.5 1.5 5.8 2.8 6.5 5.2 3.5 4.2 3.4 5.1 4.6 4.7 2.3 3.0 6.5 8.7 0.0 5.1 6.8 4.1 4.9 3.1 5.8 2.1 6.9 4.6 8.1 1.4 3.3 2.5 9.0 5.3 4.1 3.2 4.0 0.0 4.2 0.0 6.0 6.1 2.9 7.7 4.1 5.2 5.9 2.1 0.8 20.3 8.1 0.7 1.9 0.0 7.3 0.0 4.6 1.8 5.9 1.3 5.1 2.3 1.3 1.9 5.8 2.7 6.3 3.9 2.3 1.3 6.9 4.7 4.6 9.4 3.1 5.7 15.3 0.0 6.9 3.4 3.7 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.3 0.4 0.0 0.2 0.3 0.4 0.0 0.3 0.0 0.0 0.3 0.1 4.4 4.8 4.6 8.5 5.7 6.1 5.9 4.6 6.0 4.9 5.8 5.1 8.3 3.2 9.1 47.0 9.4 2.7 4.6 2.7 4.6 10.0 4.2 3.6 12.7 5.7 4.1 3.7 6.2 0.2 7.5 2.1 0.0 3.5 4.1 10.9 5.6 9.4 0.0 4.4 62.7 3.5 0.0 8.2 1.5 7.3 5.1 5.3 5.3 1.6 1.6 13.5 59.6 7.5 2.0 2.2 1.8 1.8 3.1 2.3 5.4 29.0 1.6 5.7 8.2 66.9 76.1 2.4 6.1 9.1 6.7 5.4 1.4 11.4 3.9 7.5 0.0 8.3 5.0 2.0 2.4 2.4 4.5 0.0 8.8 5.9 3.4 4.6 CHMP1A "CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A" ENSG00000131165 "Charged multivesicular body protein 1A" Q9HD42 16 89640816-89657738 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transcription, Transcription regulation, Transport" Repressor Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA006776 Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Centrosome, Cytosol" "HPA006776: AB_1078520" "unprognostic (7.12e-2)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (1.41e-2)" "unprognostic (7.29e-2)" "unprognostic (8.03e-3)" "unprognostic (1.28e-3)" "unprognostic (3.92e-3)" "unprognostic (2.42e-1)" "unprognostic (3.53e-1)" "unprognostic (2.21e-1)" "unprognostic (2.56e-1)" "unprognostic (7.98e-3)" "unprognostic (1.59e-2)" "unprognostic (4.19e-2)" "unprognostic (3.24e-1)" "unprognostic (1.73e-1)" 30.3 31.2 46.3 21.1 44.5 31.4 29.4 41.2 53.4 34.3 36.9 42.7 37.8 35.8 17.0 65.4 31.6 24.8 33.1 46.8 42.7 36.6 30.6 28.7 27.5 45.3 44.3 25.0 25.7 30.4 24.8 24.7 44.0 33.5 23.0 5.4 31.8 22.1 50.0 48.7 42.5 22.4 44.3 31.6 34.0 37.3 45.7 30.5 28.3 25.9 24.3 35.6 36.9 44.2 70.5 66.3 29.5 46.2 42.2 38.2 75.3 53.0 54.3 79.3 38.7 97.1 111.5 37.7 53.2 70.1 52.9 88.3 52.6 69.7 36.7 34.2 82.7 31.0 23.4 108.5 57.8 23.0 31.7 54.7 75.6 74.6 33.8 42.7 41.2 46.2 69.9 18.2 45.6 141.4 55.1 88.3 58.1 78.6 63.5 60.1 58.3 39.8 60.4 43.0 52.7 70.8 103.5 34.3 38.1 27.5 117.6 48.5 63.1 52.7 61.6 65.3 45.8 52.1 59.1 51.1 88.1 54.9 62.5 66.7 51.6 108.9 54.4 62.7 42.0 36.3 43.6 50.1 44.2 33.4 27.5 33.4 86.0 49.8 82.3 49.4 58.5 64.1 46.3 44.5 41.2 53.4 46.8 42.7 45.3 44.3 44.0 44.3 45.7 44.2 31.1 32.1 23.6 17.3 27.5 23.8 24.5 28.8 13.1 24.6 33.9 27.6 16.8 28.6 26.6 31.3 8.4 57.7 43.2 147.3 37.2 55.3 56.4 27.2 26.3 28.3 44.3 16.2 8.8 59.5 74.4 26.9 36.2 35.0 27.9 33.0 23.2 31.1 47.6 43.7 7.9 57.7 30.5 30.4 23.8 125.5 20.5 28.3 23.2 11.2 62.8 36.3 43.3 11.1 9.5 84.7 121.6 24.0 14.8 31.7 109.6 40.9 22.4 20.5 26.3 17.1 27.1 45.4 33.3 26.3 32.5 66.2 28.6 28.8 58.2 36.5 CHMP2A "BC-2, CHMP2, VPS2, VPS2A" ENSG00000130724 "Charged multivesicular body protein 2A" O43633 19 58551566-58555105 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041153, HPA042031" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 230000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA041153: AB_10964358, HPA042031: AB_10961727" "unprognostic (1.80e-1)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (2.54e-1)" "unprognostic (3.86e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (3.09e-2)" "unprognostic (4.23e-2)" "unprognostic (2.71e-2)" 131.8 185.9 144.9 86.8 149.6 162.3 125.1 153.7 171.9 108.9 143.5 141.3 113.4 111.7 150.1 154.9 104.6 83.1 182.6 144.4 147.8 163.3 161.3 116.9 81.9 151.1 147.0 101.9 125.0 147.8 118.7 95.8 151.3 112.5 124.1 75.2 137.2 97.1 222.9 158.4 121.9 83.6 149.0 121.2 143.8 73.9 146.8 82.6 123.2 151.7 95.1 114.3 113.7 157.4 110.4 290.9 91.4 85.0 138.9 172.9 112.9 100.0 204.3 52.0 56.0 86.3 160.1 29.3 143.2 168.1 149.2 87.7 76.1 190.4 43.7 98.8 628.2 71.8 214.0 134.7 266.6 121.1 108.0 201.5 266.0 81.5 257.8 175.3 153.1 135.5 86.8 135.6 159.5 187.1 153.7 111.3 38.3 304.2 220.3 65.2 78.6 222.0 230.1 246.8 107.3 181.2 162.0 213.7 123.4 57.3 164.3 121.5 174.4 262.0 37.7 77.2 117.3 339.0 404.9 95.2 185.0 141.0 176.6 278.9 247.4 351.1 134.9 232.7 114.5 127.0 148.0 153.1 216.2 123.0 102.0 116.3 820.6 131.6 243.9 197.1 215.5 208.4 144.9 149.6 153.7 171.9 144.4 147.8 151.1 147.0 151.3 149.0 146.8 157.4 166.1 99.3 119.8 9.4 72.9 165.6 261.4 287.7 69.4 73.9 124.7 120.6 118.7 154.4 207.2 165.5 16.7 288.8 76.5 555.2 442.2 332.6 121.9 194.0 109.2 143.6 155.4 142.5 5.3 522.5 296.8 113.5 115.7 198.8 121.5 102.1 142.5 214.0 269.1 52.2 5.6 296.6 217.7 142.0 145.8 90.9 145.1 134.5 215.3 6.5 203.6 217.6 147.2 3.0 13.4 479.8 615.3 133.2 77.3 258.5 607.0 599.8 242.1 94.3 85.5 103.9 169.7 116.8 89.7 109.5 198.5 460.0 89.2 149.3 226.3 372.7 CHMP5 "C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60" ENSG00000086065 "Charged multivesicular body protein 5" Q9NZZ3 9 33264879-33282070 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033874, HPA042883, HPA056437" Enhanced Supported Microtubules,Midbody,Cytosol Yes No 22000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Microtubules, Cytosol" Midbody "CAB033874: AB_10608611, HPA042883: AB_2678212, HPA056437: AB_2683133" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (9.08e-2)" "unprognostic (1.07e-1)" "unprognostic (2.32e-1)" "unprognostic (4.56e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-2)" "unprognostic (4.71e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.66e-1)" "prognostic favorable (2.87e-7)" "unprognostic (2.22e-1)" "unprognostic (9.59e-2)" "unprognostic (1.73e-1)" "unprognostic (7.31e-2)" 54.6 54.6 48.3 36.7 49.2 30.5 49.6 50.4 63.8 56.4 50.0 55.7 55.2 41.3 48.1 64.6 43.8 42.1 50.8 49.0 50.3 77.8 56.3 53.5 41.6 50.4 49.7 42.9 32.7 63.9 49.7 63.8 50.7 54.8 55.9 53.8 43.7 39.4 48.2 47.0 59.2 33.9 52.7 43.5 54.6 36.2 49.4 44.9 55.8 44.3 38.1 49.7 56.5 56.9 92.2 66.5 67.0 43.5 99.0 89.0 61.9 90.1 99.7 138.3 152.6 50.9 56.9 49.0 96.3 84.3 95.9 39.2 70.5 72.8 111.1 102.5 49.3 41.5 129.7 55.8 85.9 53.4 78.8 95.6 131.3 93.6 86.4 114.5 73.3 68.3 44.9 63.6 110.5 41.3 56.1 164.1 61.8 70.1 80.6 34.0 59.2 32.9 115.2 48.7 32.7 83.6 91.0 53.4 87.2 77.8 54.2 82.7 74.4 69.5 73.0 60.2 80.8 42.3 87.6 57.0 100.5 36.0 45.6 98.6 50.3 106.3 25.3 56.5 27.6 31.0 33.7 33.8 46.5 26.4 30.6 29.4 129.4 47.4 67.3 71.2 43.4 51.3 48.3 49.2 50.4 63.8 49.0 50.3 50.4 49.7 50.7 52.7 49.4 56.9 182.7 89.8 59.0 14.0 52.9 188.1 156.2 372.5 71.7 63.7 85.2 75.1 64.7 94.4 228.6 110.3 27.1 172.0 77.4 241.0 285.7 141.7 245.2 228.0 90.6 133.8 80.2 90.1 19.6 86.1 186.1 104.4 56.1 167.0 58.4 66.5 97.5 70.5 154.9 26.9 19.0 137.9 246.2 100.9 103.2 35.9 93.2 95.3 117.4 15.0 166.3 156.2 38.1 14.6 26.8 151.9 247.9 104.6 45.2 182.4 226.3 355.2 328.9 68.2 85.5 97.0 130.0 99.5 68.7 70.1 236.3 259.0 68.5 71.4 78.5 246.0 CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 305.0;skin 1: 149.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 345.0;Paneth cells: 274.0;Proximal enterocytes: 654.2;Undifferentiated cells: 205.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 7.3;hTERT-RPE1: 10.2;NB-4: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" 0.4 0.2 1.1 3.8 1.1 2.2 4.3 3.6 1.3 14.0 0.0 146.7 305.0 0.9 1.1 0.6 0.9 0.4 0.4 0.7 1.6 4.1 0.7 0.6 0.8 0.5 0.1 0.4 0.5 0.1 0.0 1.4 0.9 3.8 147.4 1.3 0.8 4.5 1.2 149.7 250.5 6.5 0.1 0.3 1.1 7.3 0.9 0.5 0.6 0.2 0.4 9.0 4.2 2.9 1.0 2.2 0.5 0.6 1.2 1.3 1.2 2.9 1.1 0.3 1.0 0.5 2.3 0.4 0.9 2.5 1.2 1.4 0.4 2.9 0.6 0.7 0.2 0.5 4.1 1.6 1.7 0.3 0.7 0.9 0.8 2.5 7.3 10.2 1.1 0.3 1.2 1.0 1.2 0.1 0.1 8.7 0.3 0.5 2.1 0.2 0.1 1.4 1.1 0.7 0.6 0.7 0.8 0.2 0.0 0.6 0.2 0.2 1.3 0.5 0.6 0.7 0.1 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.0 1.1 1.1 3.6 1.3 0.7 1.6 0.5 0.1 0.9 0.1 0.9 2.9 0.0 0.0 0.0 0.0 0.0 10.3 8.7 6.1 0.0 0.0 0.0 0.1 0.1 0.0 24.4 1.8 0.0 0.9 0.0 345.0 0.0 0.0 0.6 1.3 0.5 0.2 9.1 0.0 0.0 0.0 4.1 0.2 0.0 3.6 4.5 0.7 0.0 0.0 0.1 0.0 0.0 70.0 12.2 0.0 1.6 0.5 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 274.0 0.0 0.0 2.5 654.2 12.9 4.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 67.5 0.7 0.2 0.2 205.4 29.9 CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538948-219543809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 163.7;Extravillous trophoblasts: 182.7;Syncytiotrophoblasts: 310.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" NA NA 570000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.96e-4)" 29.9 45.7 26.9 12.5 24.9 1.7 22.3 25.8 34.2 59.1 36.7 21.9 26.7 55.9 13.7 27.3 30.2 24.2 134.8 38.4 31.2 41.1 97.8 42.8 6.5 34.0 30.4 127.4 138.9 24.6 128.3 40.6 32.1 58.6 4.7 8.5 56.1 25.6 16.3 26.2 23.2 12.6 27.4 16.6 40.9 97.5 33.2 3.6 52.8 3.9 4.5 34.3 30.0 34.0 67.5 13.0 9.6 81.0 36.0 55.8 109.7 66.4 55.4 18.5 16.8 36.8 57.5 20.7 139.0 64.6 63.3 84.1 6.3 40.3 2.9 32.3 22.5 7.4 18.0 161.9 49.8 6.6 42.1 75.0 69.2 18.8 17.9 66.7 0.1 7.1 47.2 49.6 17.7 105.5 1.0 17.6 39.8 22.8 50.6 0.1 30.4 41.6 22.4 29.7 23.4 36.0 32.1 30.7 94.3 17.9 10.5 22.6 1.6 67.9 37.1 81.9 35.2 58.9 19.9 9.7 62.1 6.7 70.4 1.7 0.0 6.5 1.9 0.1 2.4 1.0 1.5 1.3 0.0 0.1 1.7 0.6 0.0 1.9 0.0 9.5 1.2 0.7 26.9 24.9 25.8 34.2 38.4 31.2 34.0 30.4 32.1 27.4 33.2 34.0 2.1 0.0 15.2 16.0 16.5 14.5 23.2 52.8 17.1 14.6 40.0 29.6 30.5 22.8 31.2 75.4 10.4 163.7 21.7 15.9 9.8 58.1 4.1 14.0 22.2 2.9 43.0 3.2 4.3 80.4 182.7 56.0 25.5 42.4 10.2 27.4 4.2 64.0 18.5 43.7 9.2 57.8 36.7 2.4 9.1 7.1 24.8 2.3 67.6 5.6 1.8 56.8 9.2 5.5 3.7 65.6 32.7 63.2 123.6 42.3 60.7 20.6 14.6 11.5 26.3 19.3 27.1 11.9 6.3 14.2 11.1 310.3 9.7 46.3 14.3 33.0 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 57.6" "Group enriched" "Detected in some" 10 "Muller glia cells: 4.0;Skeletal myocytes: 4.4" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RH-30: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056404, HPA065404" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA056404: AB_2732603, HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 6.3 0.7 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in many" "Muller glia cells: 114.4;NK-cells: 233.8;Plasma cells: 79.3;Sertoli cells: 92.1;Theca cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Cell line enhanced" "Detected in many" "ASC diff: 57.7;ASC TERT1: 58.8;HEL: 48.2;HHSteC: 118.4;HMC-1: 55.4;HSkMC: 62.3;U-266/70: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" 7.7 2.7 17.8 8.1 13.7 16.8 6.3 16.7 14.6 5.7 6.0 3.0 2.1 8.4 1.4 1.1 2.1 1.7 5.6 9.7 13.4 8.4 1.3 7.5 7.7 31.0 18.4 4.9 1.3 0.9 6.9 10.3 28.1 7.4 1.1 11.0 2.7 9.9 1.6 4.4 7.5 3.7 21.4 18.2 3.4 1.7 28.7 14.5 6.7 0.8 5.4 7.1 7.6 48.4 0.0 0.3 3.1 2.6 57.7 58.8 0.2 3.3 9.5 2.3 2.1 0.0 0.0 0.6 2.0 2.3 3.1 0.1 2.3 8.2 1.2 0.8 1.5 48.2 0.1 0.0 118.4 1.2 55.4 62.3 9.7 3.1 10.1 3.6 3.6 7.2 5.5 2.9 15.4 0.0 9.1 12.2 16.5 0.0 8.0 0.5 1.0 0.1 1.7 2.2 3.7 0.0 0.7 0.0 5.6 2.9 0.0 1.9 12.3 7.0 4.1 9.5 13.9 52.4 0.8 3.3 13.8 9.3 37.4 0.7 0.5 0.7 0.3 4.3 0.0 1.1 0.1 0.2 1.6 0.8 0.6 0.5 0.3 4.9 11.4 0.1 0.5 0.9 17.8 13.7 16.7 14.6 9.7 13.4 31.0 18.4 28.1 21.4 28.7 48.4 11.3 0.0 0.0 3.6 17.7 2.4 7.3 2.5 0.0 25.0 2.8 2.7 1.4 0.0 1.8 3.7 2.1 0.6 41.9 0.0 0.0 0.4 0.2 5.7 29.8 9.4 0.0 39.1 6.8 0.2 0.6 14.4 2.0 6.5 11.4 12.5 3.6 0.4 2.8 1.7 8.1 0.0 0.0 10.3 32.2 1.3 12.8 20.2 17.8 1.0 13.6 114.4 233.8 2.5 6.1 5.9 0.0 2.2 79.3 13.1 0.0 0.0 0.1 23.8 92.1 0.8 20.2 0.0 2.2 0.1 0.6 1.0 9.8 58.1 1.3 14.8 CIPC KIAA1737 ENSG00000198894 "CLOCK interacting pacemaker" Q9C0C6 14 77098126-77117287 "Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.1" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000644 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Nucleoli "HPA000644: AB_1079206" "unprognostic (3.93e-2)" "unprognostic (6.71e-2)" "unprognostic (2.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (2.41e-1)" "unprognostic (6.67e-3)" "unprognostic (3.73e-2)" "unprognostic (1.74e-1)" "unprognostic (2.31e-2)" "unprognostic (3.20e-1)" "prognostic favorable (1.77e-10)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "unprognostic (1.13e-1)" "unprognostic (1.21e-1)" 13.2 9.6 41.3 8.4 53.0 4.2 15.8 48.0 41.1 16.8 24.7 26.8 10.3 14.6 13.5 22.1 30.4 9.0 39.8 46.5 44.1 14.2 15.4 11.1 8.4 47.5 48.2 9.1 9.7 29.5 13.5 9.0 43.9 25.5 19.9 41.2 20.5 24.8 132.1 15.4 11.4 16.5 42.3 9.1 11.4 11.7 53.3 10.3 20.4 82.4 10.1 17.2 15.5 49.6 9.4 12.6 25.4 16.8 10.1 8.0 15.4 6.0 9.4 10.9 9.8 10.3 19.4 23.3 5.9 9.7 9.6 14.3 23.7 9.4 14.3 12.3 6.4 14.9 9.8 9.5 9.7 8.4 10.7 9.4 17.9 10.6 6.5 14.1 12.7 19.2 14.0 8.8 8.1 21.4 20.2 10.2 10.6 21.3 10.9 20.2 11.3 14.0 11.0 16.1 35.9 13.4 11.0 17.4 14.9 10.7 27.2 8.6 14.9 7.0 15.1 10.0 7.6 8.4 7.1 11.1 13.2 7.1 14.8 4.3 4.5 1.6 2.6 5.1 4.1 7.9 3.6 2.7 5.4 7.1 3.8 2.8 5.5 5.5 3.8 2.0 4.1 3.6 41.3 53.0 48.0 41.1 46.5 44.1 47.5 48.2 43.9 42.3 53.3 49.6 8.5 16.0 18.4 33.6 4.7 9.1 8.2 5.3 12.5 29.3 18.3 12.6 49.9 8.6 12.6 11.0 58.4 7.4 5.5 43.5 9.8 4.2 11.0 39.8 9.2 7.0 17.4 6.5 16.4 5.6 5.0 5.6 9.2 20.3 1.3 5.8 7.1 29.5 15.2 11.8 20.2 14.8 30.5 16.0 6.6 15.8 4.1 7.2 8.8 9.4 5.8 22.8 2.1 21.1 58.7 5.1 12.4 14.3 4.2 8.3 18.1 6.0 30.5 36.4 13.1 7.9 9.3 19.9 9.1 10.4 9.8 13.5 3.1 7.1 13.7 7.1 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLBA1 C14orf79 ENSG00000140104 "Clathrin binding box of aftiphilin containing 1" Q96F83 14 104985775-105010482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Endometrial ciliated cells: 29.9;Respiratory ciliated cells: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042052, HPA061117" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA042052: AB_2677822, HPA061117: AB_2684434" "unprognostic (1.49e-2)" "unprognostic (4.04e-2)" "unprognostic (4.84e-2)" "unprognostic (2.88e-2)" "unprognostic (5.51e-2)" "unprognostic (1.49e-1)" "unprognostic (5.77e-2)" "unprognostic (9.43e-3)" "unprognostic (1.78e-1)" "unprognostic (8.21e-2)" "unprognostic (3.50e-2)" "unprognostic (2.30e-1)" "unprognostic (4.39e-3)" "unprognostic (3.12e-2)" "unprognostic (1.11e-2)" "unprognostic (9.30e-2)" "unprognostic (2.95e-1)" 3.6 7.8 5.7 1.3 6.0 1.6 5.8 3.7 6.4 8.0 11.1 5.6 1.7 7.6 11.5 7.8 14.9 3.4 3.0 6.2 7.5 15.9 6.9 5.8 1.5 5.5 6.5 7.1 14.4 9.3 21.7 1.8 4.4 9.6 2.6 3.1 8.1 6.1 1.8 7.6 3.1 3.3 5.0 3.2 5.9 23.9 7.0 1.3 18.2 1.2 1.2 6.0 5.4 4.2 5.1 8.9 2.7 8.3 2.6 3.8 4.1 4.0 3.7 4.7 2.1 0.8 8.7 0.5 8.3 4.0 2.5 10.9 1.0 6.0 3.0 4.2 3.2 0.3 8.9 0.4 9.2 2.3 2.2 2.3 13.6 5.1 10.1 8.0 2.7 4.2 3.1 1.4 2.8 17.5 0.9 6.6 3.4 5.0 8.5 3.2 1.5 2.9 10.4 2.9 17.1 8.9 5.7 2.5 5.0 1.7 18.0 3.1 3.0 5.9 2.7 12.0 3.1 1.6 1.1 0.5 7.6 0.7 4.2 0.4 0.2 0.0 0.2 0.2 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.1 0.1 5.7 6.0 3.7 6.4 6.2 7.5 5.5 6.5 4.4 5.0 7.0 4.2 1.0 16.0 3.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 7.4 7.4 0.0 0.0 2.5 16.5 0.0 1.8 0.4 0.0 3.9 7.9 0.0 29.9 8.1 0.9 0.0 0.0 0.0 1.3 0.8 1.3 0.0 8.8 2.5 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 6.5 19.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.4 6.5 0.0 0.0 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 373.9;intestine: 257.8" "Group enriched" "Detected in many" 6 "Distal enterocytes: 597.0;Paneth cells: 183.2;Squamous epithelial cells: 158.7;Urothelial cells: 176.9" "Cancer enhanced" "Detected in many" "cervical cancer: 21.4;urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 1368 "RT4: 430.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" NA NA 150000 "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: AB_2291679, HPA064770: " "unprognostic (1.38e-4)" "unprognostic (1.52e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.73e-2)" "unprognostic (7.03e-2)" "prognostic favorable (8.63e-4)" "unprognostic (7.59e-2)" "unprognostic (3.35e-1)" "unprognostic (1.26e-1)" "unprognostic (6.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (2.29e-1)" "unprognostic (5.69e-2)" "unprognostic (3.43e-2)" 0.6 0.0 6.3 13.9 9.4 0.0 2.2 6.7 8.0 44.6 3.2 257.8 0.1 0.1 0.1 373.9 0.2 0.2 0.1 6.2 6.6 0.1 0.1 0.0 0.0 10.9 7.0 0.0 0.1 0.0 0.5 0.0 8.7 2.5 143.5 0.0 23.1 0.2 0.1 17.1 29.1 2.9 7.1 0.1 0.6 0.3 8.0 0.1 0.0 0.0 30.1 99.3 66.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 430.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.4 6.7 8.0 6.2 6.6 10.9 7.0 8.7 7.1 8.0 12.7 0.1 0.0 0.0 0.0 2.9 3.3 40.3 6.5 2.8 0.0 1.9 1.8 0.4 0.0 17.5 1.8 0.0 0.0 0.2 597.0 0.0 0.0 0.4 7.3 0.1 0.3 8.3 0.0 0.1 0.0 0.0 0.4 0.0 3.5 8.9 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 183.2 0.0 1.2 9.7 4.7 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 158.7 11.9 0.0 1.5 0.0 12.0 176.9 CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 214.4" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 4 "CACO-2: 49.0;RH-30: 66.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" 2.1 2.5 1.7 1.7 1.9 1.5 1.6 3.8 1.6 1.8 2.5 2.4 4.9 4.0 23.7 2.4 3.0 3.9 1.3 1.5 2.9 46.2 16.9 2.8 1.3 3.2 3.2 7.0 2.1 1.4 2.3 5.8 3.7 1.7 2.8 3.4 2.5 1.0 4.0 4.8 3.8 2.9 2.5 1.8 2.9 2.1 2.7 1.1 2.2 2.8 1.2 1.4 2.0 2.3 2.9 5.4 4.2 5.5 12.8 7.5 7.9 2.8 1.2 1.6 1.9 49.0 3.0 3.5 1.2 2.5 9.7 2.8 9.9 1.7 2.2 1.1 7.5 3.3 2.7 12.8 7.2 4.1 5.7 4.9 1.6 3.7 5.9 1.2 5.8 4.0 4.3 4.7 5.3 3.2 1.6 1.4 5.7 7.4 2.4 1.9 66.0 5.2 6.0 5.5 7.2 5.2 3.3 3.0 5.1 14.1 3.0 2.1 3.8 1.6 3.7 12.7 1.4 3.6 11.9 7.3 2.8 6.6 8.5 0.0 0.9 0.0 0.1 0.9 0.1 0.1 0.2 0.2 2.6 0.1 0.0 0.0 0.2 0.1 0.1 2.8 0.0 0.3 1.7 1.9 3.8 1.6 1.5 2.9 3.2 3.2 3.7 2.5 2.7 2.3 4.3 9.6 8.4 20.5 2.1 7.1 1.8 1.6 5.2 27.4 1.8 1.4 1.9 2.8 2.3 12.9 2.1 6.2 17.7 11.3 11.7 4.1 2.0 8.0 10.0 5.5 0.0 3.4 11.5 3.5 2.6 7.9 8.6 22.8 2.5 0.8 1.4 35.2 11.1 8.4 15.6 6.6 4.1 17.6 19.8 0.6 5.3 10.9 3.6 46.9 10.1 2.7 2.1 20.6 9.6 7.7 7.3 13.2 2.2 4.0 20.4 38.8 4.2 4.3 0.0 214.4 4.8 0.9 2.3 8.1 9.5 5.1 1.9 9.3 7.0 4.8 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLDND1 "C3orf4, Z38" ENSG00000080822 "Claudin domain containing 1" Q9NY35 3 98497912-98523066 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 1093.8;choroid plexus: 316.7" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 575.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029841 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA029841: AB_10600658" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.13e-2)" "unprognostic (8.50e-2)" "unprognostic (9.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.43e-3)" "unprognostic (4.08e-2)" "unprognostic (3.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.84e-6)" "unprognostic (5.73e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (1.51e-1)" 53.6 42.6 477.0 40.7 757.5 49.1 48.8 696.1 804.5 59.0 316.7 58.3 36.5 58.8 43.1 77.8 46.7 50.6 57.6 483.5 577.6 39.2 50.0 46.9 54.7 851.3 670.8 63.9 23.6 32.6 28.2 73.8 837.8 49.5 46.9 46.5 29.8 51.9 43.6 64.8 42.2 63.5 643.7 44.0 37.4 106.6 638.3 44.7 40.5 68.9 54.9 64.0 65.8 1093.8 67.3 26.2 83.2 50.7 96.0 75.0 44.6 52.0 69.8 71.0 97.8 52.7 66.9 33.7 69.1 49.4 134.3 90.4 61.6 39.9 124.3 79.3 27.5 68.3 18.6 48.1 76.2 62.7 67.3 88.4 207.6 54.0 58.7 77.6 79.1 64.7 35.4 100.6 102.9 33.4 47.8 42.8 75.1 28.7 55.9 31.9 110.6 43.4 67.7 30.0 30.1 82.6 74.6 24.4 108.5 110.5 24.5 52.8 75.1 94.6 86.2 65.3 69.3 130.8 59.8 53.9 154.9 61.0 125.2 179.8 91.0 103.9 102.1 55.4 193.5 101.5 190.3 187.1 98.9 99.3 76.6 78.1 70.2 274.0 56.7 63.9 399.7 155.1 477.0 757.5 696.1 804.5 483.5 577.6 851.3 670.8 837.8 643.7 638.3 1093.8 83.3 35.3 36.6 17.9 72.1 144.0 131.7 122.3 87.0 20.1 43.6 45.3 53.8 17.2 71.4 27.6 25.0 52.0 72.8 16.9 29.4 21.2 105.3 21.1 47.7 70.8 28.7 65.4 25.1 16.2 160.6 86.6 30.1 41.7 36.8 25.2 61.4 19.4 35.6 15.2 23.6 19.6 89.5 29.2 168.1 76.7 51.6 46.9 113.8 20.6 42.3 28.1 38.1 30.7 575.2 30.3 16.8 46.6 131.7 98.1 34.6 23.3 27.5 35.0 52.6 53.2 128.4 182.4 55.3 90.1 196.5 95.8 147.1 22.8 17.5 121.9 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLN6 "FLJ20561, HsT18960, nclf" ENSG00000128973 "CLN6 transmembrane ER protein" Q9NWW5 15 68206992-68257211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.8;Hofbauer cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066046, HPA066759" Approved Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Endoplasmic reticulum" "Nucleoli, Vesicles" "HPA066046: AB_2685604, HPA066759: " "unprognostic (1.01e-1)" "unprognostic (1.54e-3)" "unprognostic (7.01e-2)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (3.08e-1)" "unprognostic (2.24e-2)" "unprognostic (5.07e-2)" "unprognostic (2.40e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-1)" "unprognostic (6.78e-2)" 11.6 17.6 12.7 14.8 13.0 29.9 11.5 13.3 14.9 11.0 13.2 17.5 14.6 9.8 6.8 16.9 9.8 9.6 9.3 12.1 12.6 20.0 22.7 13.2 16.2 13.3 13.1 6.8 19.1 10.4 10.1 11.6 13.8 12.4 14.9 11.8 14.8 9.2 17.0 14.7 14.6 10.4 12.8 20.7 13.3 10.9 13.0 11.6 12.9 7.3 16.7 10.7 9.6 14.5 38.2 93.1 23.9 33.9 14.5 11.8 57.1 35.3 17.0 42.8 34.9 72.1 60.5 57.6 17.2 21.4 31.7 69.5 69.8 34.5 17.0 38.5 82.3 84.3 66.1 54.3 29.7 95.6 58.1 20.8 11.4 34.7 23.7 9.0 29.1 33.1 56.9 116.0 33.6 103.8 44.0 69.4 57.1 67.3 38.3 42.1 71.8 80.6 36.2 97.0 48.2 20.0 39.5 61.7 34.3 18.0 33.1 95.5 19.3 48.1 55.7 35.8 127.2 81.3 97.3 47.4 30.0 115.4 47.6 0.0 8.8 0.6 3.0 13.0 4.0 2.9 2.2 4.3 5.2 2.3 2.8 1.3 10.5 2.0 16.1 4.4 2.3 3.5 12.7 13.0 13.3 14.9 12.1 12.6 13.3 13.1 13.8 12.8 13.0 14.5 1.4 9.6 6.9 7.2 13.4 20.1 22.0 13.9 14.8 181.8 2.0 1.9 27.4 10.0 9.6 5.5 16.7 42.8 7.1 22.7 0.0 3.3 0.4 1.0 4.8 9.7 15.1 32.8 8.9 1.8 58.4 9.1 8.2 1.4 8.9 5.6 11.0 21.9 88.4 21.9 8.1 20.5 16.2 24.2 14.0 1.4 9.0 11.3 19.6 8.4 12.9 16.9 11.3 5.0 10.2 3.6 26.0 8.2 33.4 23.7 15.6 2.1 3.3 32.7 6.6 7.5 5.6 1.0 19.5 21.1 14.1 21.8 9.5 5.3 35.6 16.3 CLNS1A "CLCI, ICln" ENSG00000074201 "Chloride nucleotide-sensitive channel 1A" P54105 11 77514936-77637794 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017840, HPA031707, HPA031708, HPA032045" Approved Supported Nucleoplasm,Microtubules,Cytosol No No 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Microtubules" "CAB017840: , HPA031707: AB_2674002, HPA031708: AB_2674003, HPA032045: AB_2674123" "unprognostic (1.30e-1)" "unprognostic (3.26e-1)" "unprognostic (5.16e-2)" "unprognostic (1.30e-2)" "unprognostic (5.12e-3)" "unprognostic (5.09e-2)" "unprognostic (9.63e-2)" "unprognostic (5.56e-2)" "unprognostic (2.06e-3)" "unprognostic (5.56e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.05e-1)" "unprognostic (9.19e-2)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" 53.1 88.7 86.1 63.1 91.8 72.3 79.9 89.3 92.7 62.2 82.0 72.7 49.7 63.5 99.6 85.3 74.8 53.2 76.4 79.9 94.1 59.6 105.6 45.7 99.5 88.0 86.6 103.3 90.0 60.2 54.0 65.6 89.8 61.2 77.5 97.0 58.2 57.5 98.4 54.0 53.6 56.8 90.5 61.9 65.7 45.7 87.9 102.8 79.0 100.7 105.4 74.6 61.0 94.8 138.4 134.7 216.6 160.7 157.1 224.8 86.8 119.1 181.3 189.0 168.9 326.5 190.0 308.6 194.5 144.6 148.1 162.8 263.0 245.6 227.2 178.6 160.1 301.9 161.7 188.8 132.5 451.8 134.1 182.9 278.9 165.9 311.7 185.5 217.4 187.1 404.8 91.9 186.6 205.0 299.2 364.5 205.7 458.8 243.9 161.5 419.8 332.7 136.7 191.9 219.0 250.1 158.2 177.7 112.1 155.2 241.8 195.8 144.4 138.7 171.2 274.4 116.8 184.3 276.6 330.1 55.0 166.9 114.4 48.1 100.6 39.1 61.1 107.1 68.9 96.5 76.1 66.3 138.7 99.5 91.1 77.8 7.1 101.2 93.6 85.3 72.8 105.7 86.1 91.8 89.3 92.7 79.9 94.1 88.0 86.6 89.8 90.5 87.9 94.8 47.9 16.0 20.3 14.7 91.6 82.7 107.0 248.2 116.7 67.2 75.4 78.6 71.6 71.4 102.6 58.8 50.1 132.9 70.0 27.4 84.1 76.4 17.0 45.1 57.4 53.1 31.8 123.6 21.7 87.5 145.9 72.5 43.8 34.5 78.0 117.0 57.5 62.2 91.1 58.9 24.3 65.3 87.5 108.7 99.3 13.6 87.7 74.9 76.5 10.3 153.8 221.9 57.7 17.6 24.9 65.4 54.3 68.4 64.8 108.2 79.3 97.6 71.6 60.3 52.6 61.8 54.5 116.0 109.4 128.0 86.1 80.6 69.2 126.7 112.5 103.9 CLPX ENSG00000166855 "Caseinolytic mitochondrial matrix peptidase chaperone subunit X" O76031 15 65148219-65185342 "Disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040262, HPA048199" Approved Supported Nucleoplasm,Mitochondria,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 49: Eosinophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Nucleoplasm, Cytosol" "HPA040262: AB_10793961, HPA048199: AB_2680312" "unprognostic (2.78e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-2)" "unprognostic (2.00e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-3)" "unprognostic (2.64e-1)" "unprognostic (3.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.53e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.93e-9)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (5.95e-2)" "unprognostic (3.50e-2)" 7.9 10.8 9.2 6.1 9.7 8.0 9.3 9.5 11.0 7.6 7.4 9.2 8.8 7.8 8.6 13.3 7.9 6.3 14.1 7.8 8.3 12.2 32.9 6.5 9.1 9.8 8.9 9.4 9.4 11.9 4.6 9.8 8.5 8.0 8.0 10.1 7.6 6.0 26.8 14.7 7.4 7.1 8.8 8.4 9.2 9.1 9.4 10.6 9.8 24.0 9.9 7.9 8.9 10.1 8.1 13.7 11.7 14.8 12.2 15.5 12.5 9.2 10.2 9.8 10.3 13.7 11.1 25.0 7.5 12.3 7.3 16.9 43.2 12.1 10.5 9.9 7.9 18.9 12.8 17.4 17.3 24.4 10.5 18.6 16.2 9.0 17.1 11.3 12.6 13.3 17.6 8.6 11.7 10.3 11.6 21.4 13.1 16.0 6.1 22.4 13.9 26.1 18.6 18.5 10.1 8.1 12.4 19.3 13.8 15.3 8.9 20.3 11.2 9.8 8.7 8.0 8.7 9.2 15.0 13.0 9.6 30.4 7.8 2.2 4.1 6.5 4.3 3.5 3.9 4.4 3.7 3.2 3.9 3.9 5.0 4.0 6.4 4.7 3.3 5.9 3.5 2.7 9.2 9.7 9.5 11.0 7.8 8.3 9.8 8.9 8.5 8.8 9.4 10.1 16.4 35.3 35.5 15.3 23.6 19.2 18.8 20.9 18.8 32.3 17.0 15.6 69.9 27.1 29.5 33.1 14.6 41.0 28.5 16.7 21.5 36.8 104.5 24.4 28.7 21.0 10.3 56.8 15.6 31.6 29.2 25.5 33.6 27.5 16.4 37.8 21.0 90.1 22.6 32.0 15.2 20.3 28.5 28.3 16.6 242.3 28.9 20.3 17.8 16.9 34.1 25.9 20.6 12.5 23.9 29.0 18.2 29.7 30.8 24.9 23.1 33.8 27.7 27.2 26.3 23.1 30.1 45.0 30.6 29.1 30.1 89.2 24.4 59.0 24.3 25.5 CLTA Lca ENSG00000122705 "Clathrin light chain A" P09496 9 36190856-36304781 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1299.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002665, HPA050918, HPA054667" Enhanced Enhanced Vesicles,Endosomes,Lysosomes NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "CAB002665: , HPA050918: AB_2681273, HPA054667: AB_2682565" "prognostic favorable (5.64e-4)" "unprognostic (7.62e-2)" "unprognostic (9.22e-2)" "unprognostic (8.45e-3)" "unprognostic (1.71e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (9.46e-5)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-3)" "unprognostic (7.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.98e-2)" 172.8 174.2 131.6 80.8 139.1 67.2 165.6 144.7 165.1 170.9 137.5 163.3 107.9 165.6 100.7 207.1 158.9 64.4 98.1 133.3 143.8 236.0 146.8 146.2 84.1 145.1 138.5 205.6 164.3 104.3 139.3 124.4 151.4 145.0 108.6 84.8 162.8 71.2 87.7 163.2 136.0 84.9 141.6 153.0 161.4 108.5 141.7 85.2 160.1 51.5 93.4 150.9 158.4 151.5 326.3 257.2 188.4 146.3 270.0 269.8 302.6 328.5 248.2 258.1 301.5 194.2 143.9 243.8 177.0 220.9 460.7 136.2 238.8 228.2 238.4 166.0 193.1 187.5 255.0 199.8 359.4 201.0 166.5 297.3 250.5 297.4 234.3 241.0 329.6 129.3 166.0 126.4 399.0 113.3 182.2 254.8 301.8 218.8 360.3 173.3 124.8 142.1 353.7 229.1 146.1 245.3 137.3 160.0 289.4 220.2 146.9 244.2 418.4 209.4 234.0 240.3 347.9 83.0 208.9 259.5 256.9 278.0 188.9 142.2 221.7 115.4 97.1 239.6 101.9 121.0 104.9 100.2 222.6 119.6 92.9 82.0 86.7 96.2 191.8 192.2 162.9 209.4 131.6 139.1 144.7 165.1 133.3 143.8 145.1 138.5 151.4 141.6 141.7 151.5 291.5 128.2 143.9 14.4 105.9 197.3 274.3 374.3 169.0 139.4 274.0 315.0 51.5 217.3 247.4 180.3 60.5 958.0 140.1 349.3 463.7 480.5 51.9 241.5 174.3 244.0 183.8 154.8 28.5 335.6 469.1 187.5 142.2 182.7 73.5 198.4 312.7 170.6 903.7 92.5 30.4 350.5 248.2 391.7 172.0 97.6 262.9 249.3 195.7 20.6 343.5 282.8 117.4 16.1 49.0 465.2 426.4 215.5 97.7 320.5 411.5 651.7 304.7 127.3 177.5 170.0 310.4 288.0 216.8 210.9 193.2 1299.5 103.7 281.6 380.0 360.4 CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 1839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 704.2;MCF7: 641.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" 102.9 133.6 125.8 50.1 125.1 40.6 82.9 117.8 176.7 180.4 125.3 133.9 92.3 85.9 23.2 473.7 82.4 34.1 320.8 130.8 129.6 90.4 82.5 96.5 32.9 136.9 122.8 107.2 68.2 70.1 112.8 57.5 138.1 88.1 45.5 37.9 128.6 44.4 322.5 453.1 99.7 41.2 114.5 68.7 123.3 38.9 127.9 43.7 69.5 120.8 58.5 106.2 300.8 133.6 229.1 107.6 29.9 128.2 65.7 49.2 244.4 286.3 110.9 178.6 127.0 140.3 103.9 49.6 165.0 130.2 71.8 213.3 51.4 704.2 69.7 341.7 95.3 33.6 163.3 87.7 102.9 53.2 85.6 52.6 241.5 98.1 114.7 36.0 84.7 39.2 65.2 123.4 100.3 641.9 84.5 81.1 24.4 189.5 158.2 91.3 52.9 165.2 95.6 92.0 127.7 43.7 136.6 148.0 103.6 34.7 61.4 101.9 185.2 64.0 96.3 117.5 165.1 96.5 73.3 68.5 51.4 112.7 74.4 6.6 19.7 61.7 13.6 15.8 7.0 5.9 11.9 13.2 20.0 10.1 10.0 10.0 36.6 15.0 20.8 16.1 24.9 8.1 125.8 125.1 117.8 176.7 130.8 129.6 136.9 122.8 138.1 114.5 127.9 133.6 113.7 57.7 19.8 8.5 54.7 634.0 238.7 155.7 180.4 310.5 105.5 124.6 208.5 72.9 93.4 82.8 64.6 141.1 82.3 794.5 135.0 324.7 9.5 58.4 72.7 102.2 151.8 43.6 25.4 453.1 586.9 136.7 193.2 85.2 48.2 40.8 70.3 96.3 111.9 336.5 24.1 348.5 114.0 80.7 226.1 13.7 122.1 88.4 220.5 6.5 85.7 136.1 107.1 8.0 15.2 1839.9 786.9 129.8 76.4 391.4 545.7 269.7 49.6 64.3 78.9 79.6 161.4 15.9 29.1 415.6 803.0 386.5 81.3 151.2 289.7 436.0 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" 105.4 95.2 42.1 89.7 54.9 96.3 81.6 67.3 103.9 92.3 36.7 121.7 74.1 83.1 126.4 82.1 67.8 88.9 90.7 60.7 65.1 125.5 117.7 82.1 75.5 95.5 52.4 73.2 56.8 186.8 51.6 139.6 95.2 97.8 128.3 163.6 68.6 104.2 88.4 81.3 73.3 121.0 43.8 78.8 91.2 71.3 68.2 76.0 114.1 83.9 86.8 101.1 51.6 55.0 293.3 426.1 207.6 207.0 345.8 280.5 240.0 305.7 321.7 268.2 278.9 264.7 175.2 200.6 340.1 436.4 296.9 186.2 313.6 255.1 356.2 214.4 166.8 328.2 248.8 414.0 262.3 228.5 182.3 266.9 154.6 408.0 262.3 211.4 302.0 99.9 334.4 280.4 429.1 511.1 135.6 65.1 179.6 263.3 248.2 118.7 343.6 244.9 297.5 404.1 184.1 216.7 188.3 122.9 180.4 270.5 290.3 142.3 385.6 492.4 287.9 237.0 317.8 213.3 320.3 181.4 357.7 151.6 305.3 16.6 33.1 21.3 17.5 36.3 21.7 13.7 16.1 19.2 36.5 12.9 13.4 15.0 19.9 18.9 32.5 22.8 22.1 23.3 42.1 54.9 67.3 103.9 60.7 65.1 95.5 52.4 95.2 43.8 68.2 55.0 62.6 99.3 107.9 80.3 46.3 63.9 44.4 75.6 28.5 91.9 58.5 34.7 77.9 71.4 103.3 77.3 60.5 109.1 60.7 184.0 27.4 76.2 23.3 95.5 95.6 79.7 120.6 115.9 137.7 97.7 47.7 84.5 99.4 106.1 68.4 75.5 120.7 185.4 182.5 85.8 135.9 120.7 77.3 195.0 93.2 77.2 74.0 128.3 53.4 79.6 102.8 53.9 38.1 73.4 124.2 106.2 76.1 93.6 83.0 86.3 102.7 132.4 128.0 65.2 78.9 66.0 82.8 52.7 38.0 60.5 79.3 107.9 45.9 81.3 127.8 91.6 CMSS1 "C3orf26, MGC4308" ENSG00000184220 "Cms1 ribosomal small subunit homolog" Q9BQ75 3 99817837-100181732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042820 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA042820: AB_10795763" "unprognostic (1.50e-1)" "unprognostic (8.28e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.13e-2)" "unprognostic (2.39e-3)" "prognostic unfavorable (5.92e-10)" "unprognostic (1.50e-1)" "unprognostic (5.92e-2)" "unprognostic (5.83e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (3.10e-4)" "unprognostic (2.18e-3)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (3.25e-1)" "unprognostic (4.04e-2)" 24.5 33.1 23.0 15.8 21.7 20.8 23.4 26.7 30.1 22.4 17.8 21.0 8.6 21.8 9.7 15.8 20.9 10.5 28.2 21.8 20.9 20.7 15.0 15.8 17.1 22.8 20.1 23.6 26.7 21.8 24.5 11.6 19.6 16.0 11.6 24.6 14.0 13.3 69.4 17.4 12.6 13.2 17.9 13.8 16.4 30.3 21.3 16.7 14.8 29.9 15.0 24.5 18.1 21.7 116.2 51.0 50.0 72.6 34.7 40.1 51.0 53.5 28.8 93.3 77.0 64.1 37.5 126.3 90.6 28.2 82.4 68.4 70.3 60.2 120.3 66.8 66.5 99.9 32.9 53.2 62.6 137.0 51.3 28.2 56.7 71.4 116.6 30.3 65.2 100.9 63.5 78.1 67.0 78.8 110.3 126.4 73.0 109.4 126.1 49.1 81.3 134.1 57.2 27.5 139.9 58.9 52.8 42.5 125.0 47.8 51.4 84.0 18.5 73.6 207.4 43.3 109.8 56.3 121.1 244.9 49.1 149.4 124.8 1.0 11.0 2.3 22.2 27.3 32.0 57.3 32.8 30.3 23.8 55.7 41.3 42.0 4.1 28.6 25.1 62.1 33.9 18.2 23.0 21.7 26.7 30.1 21.8 20.9 22.8 20.1 19.6 17.9 21.3 21.7 26.7 6.4 19.4 48.6 41.3 62.2 37.4 45.5 26.2 32.8 43.8 40.4 41.7 42.9 23.2 62.5 18.8 41.7 25.1 8.5 97.8 42.1 165.0 21.7 56.8 38.7 15.0 30.9 154.3 47.7 56.6 44.3 9.7 19.8 62.1 47.7 24.7 61.4 27.2 127.9 132.8 14.4 16.2 7.9 45.5 215.8 50.7 18.7 37.4 58.1 12.8 28.0 19.6 114.1 116.2 35.8 4.6 58.6 36.2 82.8 1.1 87.9 22.4 27.0 26.3 67.3 50.1 163.4 146.1 21.3 66.1 21.9 30.1 54.1 22.6 27.0 CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Granulosa cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" 4.5 5.0 36.4 2.7 34.1 2.5 5.7 32.8 34.5 3.9 28.3 16.1 11.9 4.4 20.1 6.0 10.6 2.9 4.1 43.1 37.1 26.3 4.1 8.4 0.6 42.1 41.7 3.4 19.2 32.7 14.4 2.1 35.4 7.7 12.6 7.8 11.1 3.8 3.3 7.7 12.9 3.4 41.8 2.0 31.4 6.9 45.5 0.5 38.6 2.1 1.1 3.2 4.1 41.6 16.0 12.9 7.8 19.1 2.6 4.2 31.7 6.6 5.9 3.5 5.6 24.2 17.7 0.7 10.8 3.9 4.8 20.0 19.7 7.8 5.2 1.3 17.2 1.7 5.3 15.2 5.6 1.4 3.0 6.7 13.4 4.2 8.1 11.9 2.0 2.3 8.0 4.1 5.1 18.5 0.1 3.2 8.7 28.6 8.6 3.5 10.6 4.9 15.2 14.2 17.9 7.1 27.4 14.6 9.3 5.6 15.3 3.4 4.3 6.5 7.0 1.8 6.6 1.4 3.3 0.7 8.1 3.2 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 36.4 34.1 32.8 34.5 43.1 37.1 42.1 41.7 35.4 41.8 45.5 41.6 2.6 22.4 11.1 32.7 0.8 5.2 8.8 21.9 4.6 9.5 23.5 10.8 7.1 15.7 19.3 23.9 8.4 5.0 1.6 51.7 13.7 15.9 1.9 20.7 2.7 4.3 39.0 0.8 68.0 24.0 29.6 3.5 27.5 12.3 4.5 67.6 1.8 6.1 2.4 30.3 37.7 24.1 20.3 2.8 0.9 3.0 2.5 1.9 3.6 7.5 4.4 24.2 0.0 37.7 51.3 30.8 19.5 3.0 0.6 29.0 30.7 19.9 40.0 11.1 6.6 3.1 8.8 6.4 7.7 7.5 5.5 2.9 0.9 2.5 43.4 19.4 CMYA5 "C5orf10, DKFZp451G223, SPRYD2, TRIM76" ENSG00000164309 "Cardiomyopathy associated 5" Q8N3K9 5 79689836-79800240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 623.5;tongue: 799.5" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 3425.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 1.3;RT4: 1.5;THP-1: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA074081, HPA077831" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles, Cytosol" "Vesicles, Plasma membrane" "HPA074081: , HPA077831: " "unprognostic (5.53e-2)" "unprognostic (9.91e-3)" "unprognostic (1.21e-2)" "unprognostic (1.49e-2)" "unprognostic (9.01e-4)" "unprognostic (7.00e-2)" "unprognostic (7.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.75e-1)" "unprognostic (5.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "unprognostic (6.30e-3)" "unprognostic (3.88e-2)" "unprognostic (7.69e-2)" "unprognostic (9.74e-2)" 0.9 0.1 1.4 0.2 1.4 0.0 3.9 1.2 2.1 1.7 3.1 1.3 0.1 5.9 4.6 6.6 2.1 0.9 155.8 0.6 0.6 2.5 1.2 0.5 0.0 1.6 2.0 14.6 0.3 3.6 2.0 1.1 1.1 6.1 0.2 1.7 6.1 2.1 623.5 2.2 0.4 4.6 1.1 0.0 0.6 0.5 1.7 0.9 2.3 799.5 0.1 2.1 1.2 0.8 0.0 0.0 0.0 0.1 0.5 0.4 0.6 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 1.0 5.4 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.2 2.1 0.6 0.6 1.6 2.0 1.1 1.1 1.7 0.8 2.7 9.6 2.8 69.5 0.4 1.3 17.9 2.9 4.6 2.0 24.4 46.6 3425.2 5.7 12.2 25.8 0.0 21.4 1.3 0.4 17.6 0.7 0.3 29.3 7.2 19.7 1.8 0.0 32.9 0.4 2.9 113.7 3.6 55.2 1.3 2.5 0.4 2.3 2.1 217.0 10.7 0.2 8.2 0.6 1.6 2.3 14.9 1.4 0.0 6.5 0.1 8.8 2.1 156.3 2.9 0.6 0.2 13.5 0.6 4.8 0.0 15.4 6.2 3.0 0.0 165.6 23.1 2.5 2.0 2.2 5.4 32.8 1.2 1.7 0.2 18.1 CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 264.4" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 1139.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.2;RT4: 7.2;U-2 OS: 3.0" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Not detected" "Not detected" HPA076168 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 79: Retina - Phototransduction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Nucleoplasm "HPA076168: AB_2686781" "unprognostic (2.68e-2)" "unprognostic (4.90e-2)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" "unprognostic (2.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.48e-6)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" 3.3 0.4 0.5 0.8 1.4 0.3 1.5 1.6 0.9 1.0 0.6 3.6 2.2 0.4 9.3 9.0 4.1 1.1 0.4 0.7 0.8 2.4 23.5 0.3 0.1 0.4 0.3 0.1 0.8 4.1 0.3 1.0 0.4 2.6 2.4 264.4 4.3 1.7 5.0 5.1 6.3 0.3 0.1 3.4 2.8 0.4 0.7 0.3 0.7 1.3 0.5 3.7 1.9 0.6 2.3 0.9 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 2.0 9.2 0.1 0.5 0.0 2.7 1.4 0.2 0.3 0.1 0.0 0.6 0.0 0.2 0.8 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.9 0.0 0.8 0.7 0.5 0.2 0.9 0.0 0.1 0.4 1.1 2.2 0.1 0.0 0.1 0.4 7.2 0.3 0.0 0.2 0.5 0.1 0.2 0.9 0.0 0.3 0.2 3.0 0.1 0.1 0.7 0.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 0.5 1.4 1.6 0.9 0.7 0.8 0.4 0.3 0.4 0.1 0.7 0.6 7.3 0.0 0.0 0.7 0.1 0.1 1.8 0.5 0.6 97.7 8.7 1.8 0.7 5.7 3.4 62.5 91.8 0.0 0.0 10.6 0.0 10.1 0.4 2.5 0.4 8.7 0.0 2.7 1.2 6.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 38.0 1.7 45.4 1.1 4.0 0.0 0.8 0.0 0.1 0.3 0.5 0.0 7.5 0.0 163.9 0.0 0.0 0.2 2.1 16.4 0.0 0.0 3.7 24.5 0.4 0.8 1139.7 0.0 0.6 17.1 0.6 1.3 10.3 2.7 0.3 0.2 0.1 4.7 35.1 CNN2 ENSG00000064666 "Calponin 2" Q99439 19 1026586-1039068 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 274.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049095 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 8400000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" Cytosol "Nucleoplasm, Actin filaments" "HPA049095: AB_2680627" "unprognostic (2.52e-2)" "unprognostic (2.69e-1)" "unprognostic (1.74e-1)" "unprognostic (4.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.31e-2)" "unprognostic (1.33e-1)" "unprognostic (2.56e-1)" "unprognostic (4.58e-2)" "unprognostic (6.56e-2)" "unprognostic (3.60e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (4.70e-7)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (2.50e-1)" "unprognostic (1.54e-1)" 76.7 22.1 6.3 149.8 7.9 208.8 82.1 9.0 11.2 88.2 30.3 64.1 25.6 118.0 20.0 131.7 88.7 78.8 60.2 6.1 6.7 65.0 42.9 152.2 184.2 9.5 7.7 164.7 69.2 8.6 22.4 37.8 9.6 84.1 33.6 7.5 89.4 68.4 8.1 76.5 64.8 56.0 7.9 154.0 75.1 12.1 9.0 52.2 79.0 7.7 169.9 86.4 79.7 13.3 230.7 75.6 206.9 257.3 104.5 196.9 162.6 204.3 221.8 249.2 192.5 263.0 191.8 151.2 203.9 367.9 58.9 221.3 123.9 324.1 164.7 104.7 10.6 109.6 122.0 205.9 415.0 97.4 230.1 337.2 150.9 158.1 118.5 405.6 142.9 110.1 64.0 225.2 206.0 44.0 8.9 91.5 256.2 184.0 35.0 52.8 72.5 170.9 247.5 265.9 0.5 14.8 252.6 34.3 27.5 149.6 247.6 163.6 349.4 134.8 140.0 210.0 208.9 105.2 86.8 297.8 79.6 117.7 220.9 560.2 142.2 631.5 243.1 180.6 393.5 231.0 301.6 324.2 217.5 201.9 250.1 252.0 845.4 213.8 209.4 96.7 347.3 393.3 6.3 7.9 9.0 11.2 6.1 6.7 9.5 7.7 9.6 7.9 9.0 13.3 10.3 60.9 60.6 0.0 140.4 97.6 274.2 142.9 178.2 1.2 36.5 66.4 6.1 15.7 78.4 36.8 10.4 12.0 66.4 47.0 62.6 63.6 0.5 29.1 52.9 26.3 15.4 44.1 0.1 138.6 99.8 50.4 49.5 40.0 59.5 44.3 37.9 29.8 54.9 0.0 0.1 51.2 42.7 87.9 103.1 1.8 8.1 90.7 14.2 2.8 129.9 0.9 91.6 0.0 0.6 186.9 27.1 76.8 85.8 60.9 3.3 5.9 37.8 7.5 32.9 10.4 70.6 1.7 3.8 135.0 87.8 11.4 160.8 1.7 32.1 170.9 CNOT10 "FLJ12890, FLJ13165" ENSG00000182973 "CCR4-NOT transcription complex subunit 10" Q9H9A5 3 32685145-32773875 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 181.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035614, HPA041450" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" Cytosol "HPA035614: AB_10669975, HPA041450: AB_2677487" "unprognostic (3.75e-1)" "unprognostic (4.57e-2)" "unprognostic (4.45e-3)" "unprognostic (6.01e-2)" "unprognostic (9.88e-2)" "unprognostic (4.60e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.88e-1)" "unprognostic (1.50e-1)" "unprognostic (5.09e-3)" "unprognostic (1.80e-1)" "unprognostic (1.81e-2)" "unprognostic (1.65e-2)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.75e-3)" "unprognostic (3.43e-1)" 8.4 7.8 5.9 11.4 6.5 17.4 12.6 7.8 7.1 10.9 7.2 11.6 9.8 10.7 11.5 9.8 14.1 8.7 7.7 5.7 6.7 10.6 12.5 9.8 14.6 6.1 5.8 12.2 9.4 13.0 10.3 8.5 6.2 9.1 13.8 6.5 8.5 7.5 9.5 13.2 10.6 10.1 6.1 14.5 9.1 39.8 6.3 19.7 12.3 5.8 16.5 9.8 8.7 7.5 24.4 26.7 27.2 25.9 12.9 14.8 181.2 20.1 20.0 28.0 31.3 20.5 20.5 39.6 13.0 14.4 18.1 20.9 32.5 26.5 27.8 34.5 33.3 51.0 23.2 20.0 37.6 42.3 18.9 10.9 23.3 30.9 40.4 18.7 23.2 36.4 54.1 30.1 16.6 20.1 38.0 20.4 41.2 28.0 25.3 37.9 18.5 39.8 18.0 28.1 15.5 29.9 29.5 41.1 24.4 19.3 40.0 47.4 14.3 17.3 24.6 23.0 33.7 30.8 67.8 39.6 17.7 31.7 21.4 18.5 12.0 17.7 11.4 17.1 12.4 15.3 18.6 13.7 15.1 17.4 18.1 16.0 9.6 10.2 25.2 8.4 16.0 12.3 5.9 6.5 7.8 7.1 5.7 6.7 6.1 5.8 6.2 6.1 6.3 7.5 11.6 16.0 22.8 28.4 19.6 10.5 7.2 13.0 9.1 16.8 9.4 9.0 13.2 14.3 15.3 14.7 33.3 14.8 21.0 15.3 5.9 12.9 60.3 23.4 12.9 14.1 15.6 21.2 37.7 13.5 17.1 12.0 15.3 14.1 10.8 17.2 12.8 9.8 11.9 15.2 36.5 10.6 10.2 18.8 14.3 34.3 9.6 14.5 12.4 20.6 37.2 7.4 10.3 29.1 35.3 11.7 16.4 10.5 17.5 6.6 15.2 7.0 29.9 20.9 6.6 14.9 12.5 63.0 33.1 10.2 14.5 8.2 20.1 17.8 14.4 7.3 CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Spermatocytes: 84.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cell line enhanced" "Detected in many" "HEL: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" 4.4 2.4 2.3 2.1 2.4 7.3 3.5 7.7 2.2 5.0 3.3 4.5 1.2 7.1 2.4 2.7 4.3 4.2 2.3 1.7 2.6 2.4 10.5 2.8 2.7 2.7 3.1 8.8 1.7 4.4 2.2 3.6 3.0 2.7 2.2 2.1 1.6 3.2 1.6 1.9 2.2 4.5 2.6 3.9 1.9 5.2 2.5 2.8 3.1 2.5 1.6 3.5 3.5 2.8 8.3 5.6 12.1 6.8 5.8 13.6 0.4 9.5 6.3 7.0 9.5 0.4 2.7 6.0 1.5 6.6 7.5 0.3 14.1 3.9 10.9 0.3 4.9 35.5 11.7 2.0 6.4 4.9 7.4 8.6 2.0 5.8 5.7 6.5 10.0 2.2 1.3 1.1 11.3 0.6 4.0 7.8 9.4 1.4 10.3 5.8 11.2 3.0 4.1 2.0 7.6 7.9 11.6 0.2 3.0 4.8 2.3 12.3 7.5 9.5 3.7 10.4 8.3 4.7 6.1 0.1 4.4 6.1 4.4 0.2 1.3 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.1 0.5 3.9 0.7 0.1 0.2 2.3 2.4 7.7 2.2 1.7 2.6 2.7 3.1 3.0 2.6 2.5 2.8 32.0 6.4 17.6 59.7 1.6 8.8 13.7 6.1 13.1 12.3 3.6 5.8 13.4 7.2 3.4 9.2 0.0 2.5 1.1 2.4 5.9 10.1 16.3 23.4 30.7 24.9 2.4 17.1 20.3 12.0 5.2 29.2 4.1 17.0 7.6 42.4 20.0 38.8 18.4 20.2 37.2 5.9 4.1 40.3 11.6 8.8 45.7 24.0 8.8 91.8 31.0 21.4 1.0 70.4 29.6 4.0 0.8 30.9 1.8 3.8 5.3 8.5 6.7 8.1 13.1 34.2 21.3 84.3 48.9 5.3 5.5 1.0 1.7 31.6 5.5 6.3 CNTNAP5 "caspr5, FLJ31966" ENSG00000155052 "Contactin associated protein family member 5" Q8WYK1 2 124025287-124915287 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 7.9" "Group enriched" "Detected in some" 49 "Excitatory neurons: 554.6;Inhibitory neurons: 906.4;Oligodendrocyte precursor cells: 760.0" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "HPA069095, HPA069356" Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA069095: AB_2686083, HPA069356: AB_2686127" "unprognostic (6.32e-3)" "unprognostic (6.38e-2)" "unprognostic (1.23e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (3.11e-2)" "unprognostic (2.62e-6)" "unprognostic (3.65e-3)" "unprognostic (5.32e-2)" "unprognostic (9.58e-2)" 0.0 0.5 2.4 0.0 0.6 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.3 5.1 0.1 0.0 0.0 0.0 6.8 6.3 0.0 0.1 0.0 0.0 0.0 7.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 7.9 4.3 5.1 6.8 6.3 7.3 0.0 7.2 0.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.1 0.0 0.0 554.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 906.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.4 0.0 1.0 0.0 760.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074753-121177610 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.0;testis: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 131.7;Spermatocytes: 385.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Approved "Centriolar satellite,Centrosome,Cytosol" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "Centriolar satellite" "HPA020468: AB_2670455, HPA020480: AB_2670457, HPA051583: AB_2681542" "unprognostic (4.33e-3)" "unprognostic (2.89e-3)" "unprognostic (2.09e-2)" "unprognostic (7.97e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.21e-5)" "unprognostic (1.05e-2)" "unprognostic (3.22e-3)" "unprognostic (3.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.78e-2)" "unprognostic (5.47e-2)" "unprognostic (3.60e-3)" "unprognostic (9.83e-3)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.13e-2)" 5.3 3.7 2.5 13.8 3.6 28.0 5.0 4.0 3.2 4.4 6.9 4.6 4.0 6.7 2.7 4.1 7.8 5.4 2.8 2.1 3.3 2.8 4.1 6.7 23.3 5.4 5.5 7.5 3.9 2.8 3.1 6.3 4.1 4.5 5.6 7.5 3.6 3.8 1.1 4.9 5.2 4.9 3.7 12.6 7.8 35.3 3.4 23.9 4.8 1.8 21.7 6.5 2.8 5.3 12.6 8.3 22.5 16.4 3.3 4.9 4.2 8.4 6.2 6.6 5.6 4.7 13.2 55.7 3.3 6.3 11.8 25.2 7.6 5.2 10.4 34.3 5.5 29.4 15.2 6.1 4.5 81.0 34.1 3.1 3.8 6.9 16.5 2.8 14.6 22.7 19.2 31.0 6.5 7.9 31.2 21.5 8.1 16.0 6.6 30.1 33.4 17.4 3.1 5.7 8.5 12.9 28.4 5.2 6.3 3.9 11.0 36.0 10.3 6.7 11.6 10.8 15.8 22.0 25.6 37.8 5.6 32.2 16.1 16.2 7.0 17.0 7.2 4.3 5.5 11.7 7.5 5.5 3.7 11.9 9.0 6.4 2.7 5.0 6.5 10.6 11.5 2.8 2.5 3.6 4.0 3.2 2.1 3.3 5.4 5.5 4.1 3.7 3.4 5.3 19.8 28.9 32.8 34.9 78.7 3.3 13.8 6.8 9.1 33.5 7.4 12.2 8.9 10.0 29.5 3.7 37.5 2.7 58.2 2.7 3.9 5.1 131.7 61.8 12.3 14.8 8.4 33.2 35.4 6.0 3.0 15.1 14.8 10.9 53.0 20.6 14.6 3.9 27.2 30.3 43.8 8.4 4.1 33.9 16.5 44.3 13.7 50.7 8.8 52.5 55.2 8.2 49.4 37.2 53.1 6.3 4.5 12.0 39.1 4.3 2.2 1.4 114.6 59.6 39.5 33.8 14.5 385.0 114.1 10.9 5.7 0.8 57.0 13.1 6.4 6.2 COA4 "CHCHD8, CMC3, E2IG2" ENSG00000181924 "Cytochrome c oxidase assembly factor 4 homolog" Q9NYJ1 11 73872667-73876901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040126 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA040126: AB_10795415" "unprognostic (7.30e-2)" "unprognostic (8.69e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.64e-3)" "unprognostic (1.49e-1)" "unprognostic (2.22e-2)" "prognostic favorable (3.87e-4)" "unprognostic (1.31e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (8.17e-2)" 45.1 96.2 46.9 36.8 52.5 25.4 39.0 51.6 52.0 37.1 46.2 44.5 49.0 35.8 32.5 48.0 40.2 40.3 63.1 46.0 49.4 70.4 99.7 31.3 47.3 51.0 50.4 37.8 46.5 49.6 34.2 37.6 51.0 45.1 42.2 15.7 42.7 36.2 72.2 33.1 49.6 32.4 50.6 37.1 41.6 31.6 50.3 32.3 55.7 55.9 36.0 54.6 37.4 56.9 106.4 201.9 80.2 119.0 70.6 86.6 79.3 107.4 75.5 126.0 107.2 147.4 132.5 91.3 214.7 90.2 99.9 105.7 124.2 146.1 98.3 120.6 115.1 156.3 118.1 141.8 130.5 107.2 115.0 109.4 136.1 207.0 136.6 70.9 120.0 87.0 135.3 87.5 118.3 210.8 83.7 168.1 104.3 422.7 205.9 96.2 174.3 244.0 137.5 101.3 72.5 121.3 99.0 110.7 295.3 78.8 162.3 108.0 83.8 102.8 91.7 212.9 142.8 103.3 125.1 313.1 57.0 132.0 121.4 18.5 49.6 12.7 35.9 52.2 47.0 58.1 42.0 37.8 61.1 48.5 44.6 48.2 3.4 43.1 51.4 80.2 47.7 38.6 46.9 52.5 51.6 52.0 46.0 49.4 51.0 50.4 51.0 50.6 50.3 56.9 48.9 35.3 36.0 6.8 48.6 53.5 75.7 89.7 47.8 19.5 64.3 86.1 66.7 85.8 55.5 55.2 22.9 168.8 36.7 97.8 129.1 89.2 37.3 77.2 90.9 49.7 72.6 68.3 3.6 94.9 111.3 54.2 69.3 72.0 62.1 83.9 33.2 184.1 97.5 18.5 5.8 98.6 28.5 44.8 34.2 13.3 55.0 44.7 28.4 2.8 55.2 67.5 49.4 8.5 18.8 98.2 85.1 38.4 47.3 139.5 174.2 266.2 47.1 18.5 6.6 81.6 51.0 78.7 34.2 86.3 51.3 122.3 39.9 150.7 121.2 98.7 COG3 SEC34 ENSG00000136152 "Component of oligomeric golgi complex 3" Q96JB2 13 45464898-45536701 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040353, HPA054470" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA040353: AB_10794027, HPA054470: AB_2732585" "unprognostic (1.75e-1)" "unprognostic (3.03e-3)" "unprognostic (1.75e-1)" "unprognostic (4.04e-3)" "unprognostic (9.69e-2)" "unprognostic (2.86e-2)" "unprognostic (2.18e-2)" "unprognostic (4.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (5.82e-2)" "unprognostic (1.21e-2)" "unprognostic (4.49e-2)" "unprognostic (7.06e-3)" "unprognostic (1.13e-1)" "unprognostic (8.25e-2)" "unprognostic (1.71e-1)" 11.2 15.0 7.5 9.3 7.7 11.8 15.6 10.5 9.3 15.2 10.5 16.2 12.6 13.0 16.8 12.4 12.2 9.5 11.8 7.4 7.2 12.3 29.5 10.4 10.7 7.0 7.0 15.1 20.8 12.3 14.9 13.0 7.0 18.7 18.9 10.0 18.0 12.4 11.4 13.2 13.2 12.1 6.8 12.4 14.7 9.7 7.5 12.2 17.0 9.7 10.9 12.7 13.1 9.4 8.3 7.4 13.9 12.6 17.9 20.4 13.2 13.5 19.1 15.4 12.8 10.8 14.9 11.3 5.9 16.2 11.4 17.7 11.6 13.7 23.3 8.9 9.3 12.7 9.2 19.2 22.1 18.8 11.7 15.4 20.3 10.3 36.1 18.6 15.2 11.0 8.3 6.8 18.7 12.9 10.5 17.6 11.4 41.5 8.7 12.1 8.1 10.6 14.4 13.4 6.9 12.5 8.7 17.1 18.2 13.1 11.7 19.3 14.4 7.4 5.7 13.9 8.7 9.4 5.4 11.7 14.2 9.4 13.5 3.5 1.9 3.6 3.4 2.2 3.6 2.2 2.6 2.9 1.4 2.3 2.9 2.7 1.7 2.5 1.3 3.4 3.0 1.7 7.5 7.7 10.5 9.3 7.4 7.2 7.0 7.0 7.0 6.8 7.5 9.4 15.8 9.6 31.4 23.2 18.9 15.8 15.2 13.1 14.2 9.7 22.0 17.9 19.7 24.3 19.8 12.9 14.6 14.2 35.5 32.5 15.6 11.6 24.1 15.0 20.1 16.7 22.2 11.4 39.3 37.9 18.8 14.3 26.0 30.8 17.1 22.4 18.9 72.8 10.8 10.1 34.7 54.5 6.1 20.9 9.0 9.0 14.0 13.3 10.6 22.5 13.2 7.6 15.5 34.2 36.9 22.7 32.8 13.5 31.3 26.6 29.4 17.3 11.7 11.2 6.6 12.8 11.7 12.7 8.9 17.7 16.1 32.8 21.2 21.7 24.4 37.3 COIL "CLN80, p80-coilin" ENSG00000121058 Coilin P38432 17 56938199-56961050 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 98.5" "Cell type enhanced" "Detected in all" "Early spermatids: 249.2;Late spermatids: 591.1;Spermatocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017524, HPA027885, HPA057480, CAB069400" Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Nucleoli "CAB017524: AB_1121780, CAB069400: , HPA027885: AB_2672421, HPA057480: " "unprognostic (1.01e-2)" "unprognostic (3.05e-1)" "prognostic favorable (1.77e-4)" "unprognostic (1.90e-2)" "unprognostic (3.19e-2)" "unprognostic (4.13e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (1.64e-1)" "unprognostic (4.07e-3)" "unprognostic (3.00e-3)" "unprognostic (2.50e-2)" "unprognostic (2.25e-2)" "unprognostic (1.28e-3)" "unprognostic (2.50e-1)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (7.71e-2)" 7.7 7.2 6.6 8.8 6.8 19.9 12.2 9.7 8.9 9.2 7.3 9.2 10.2 10.4 11.6 9.7 9.8 7.1 8.0 6.6 7.0 8.7 13.0 7.6 12.8 6.7 6.7 11.9 8.7 12.3 6.2 13.0 7.4 9.3 10.6 12.6 9.8 7.7 11.5 9.8 10.0 8.5 6.8 10.3 9.2 98.5 6.6 13.2 12.1 9.1 13.5 9.3 8.7 8.1 25.0 18.6 37.4 14.5 12.5 14.9 25.8 17.5 16.4 26.1 27.7 25.6 21.0 29.9 34.6 14.0 19.5 14.1 25.6 20.2 37.1 36.1 32.3 48.7 17.4 29.2 13.5 41.5 28.5 13.9 24.7 19.7 21.1 15.5 22.6 17.4 42.9 24.3 24.8 31.6 32.9 26.3 22.0 27.4 18.4 15.5 45.9 23.9 18.1 24.7 31.6 31.2 11.7 11.5 30.1 21.5 41.8 40.0 16.0 30.2 22.7 14.8 23.0 35.6 47.7 34.5 15.8 22.7 18.8 22.3 13.3 17.5 15.5 12.6 17.5 27.6 17.0 16.6 13.5 25.0 19.5 18.9 8.1 16.0 17.2 16.4 18.6 10.1 6.6 6.8 9.7 8.9 6.6 7.0 6.7 6.7 7.4 6.8 6.6 8.1 21.3 12.8 21.0 6.8 26.5 18.7 39.5 34.0 21.1 35.9 21.6 22.5 14.1 22.8 28.3 14.7 37.5 42.2 26.2 12.5 13.7 30.1 249.2 22.7 23.1 26.6 23.9 17.5 8.8 27.7 32.3 23.5 18.3 19.9 22.2 20.3 22.5 23.9 22.7 25.2 10.9 16.5 16.2 16.5 10.4 591.1 42.3 12.3 3.6 10.3 19.6 28.5 34.0 9.5 13.3 23.5 17.3 30.5 15.1 32.2 16.6 23.0 22.0 52.4 13.1 24.9 21.9 142.2 46.8 20.3 22.7 29.1 23.3 17.1 20.8 29.0 COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;retina: 24.7;testis: 19.1" "Cell type enhanced" "Detected in some" "Early spermatids: 107.1;Inhibitory neurons: 275.3;Late spermatids: 39.2;Rod photoreceptor cells: 71.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HeLa: 47.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: AB_10600802" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (8.87e-5)" "unprognostic (2.43e-2)" "unprognostic (3.20e-1)" "unprognostic (7.62e-3)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (3.53e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (5.30e-3)" "unprognostic (2.82e-3)" "unprognostic (9.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" 6.1 0.5 13.4 0.1 10.3 0.0 2.8 0.0 30.0 1.1 0.3 0.4 2.9 0.6 1.6 0.4 0.9 2.2 0.5 17.8 13.7 1.9 2.2 0.2 0.1 6.5 9.4 1.0 0.2 1.3 7.0 0.3 1.0 0.5 0.3 24.7 4.9 0.5 1.0 0.7 2.5 0.8 6.9 0.8 0.3 19.1 8.9 0.5 2.8 0.3 0.1 0.7 1.0 1.7 0.0 0.0 5.3 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 2.7 0.0 0.1 0.0 3.2 5.9 47.6 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.2 0.0 0.1 1.2 0.2 5.6 0.0 0.8 0.0 1.6 0.0 0.1 0.0 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.2 1.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 10.3 0.0 30.0 17.8 13.7 6.5 9.4 1.0 6.9 8.9 1.7 8.2 0.0 0.0 12.4 0.1 0.0 0.1 0.0 2.2 2.1 0.4 0.6 1.0 0.0 0.6 1.8 4.2 0.0 0.0 0.0 0.0 0.0 107.1 6.5 2.0 1.6 0.0 0.0 20.5 0.0 0.0 0.7 0.0 18.9 0.0 0.5 0.7 0.0 0.0 1.7 275.3 0.0 0.0 0.0 0.4 39.2 0.6 0.2 0.0 10.3 0.0 2.8 0.0 16.6 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 71.5 0.0 4.7 24.6 7.8 1.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COMMD3-BMI1 ENSG00000269897 "COMMD3-BMI1 readthrough" 10 22316388-22329542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.1;testis: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 23.3;MOLT-4: 12.7;U-937: 23.8" "HPA030471, HPA030472, HPA036584" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Nuclear bodies" "Nucleoplasm, Nucleoli, Cytosol" "HPA030471: AB_2673491, HPA030472: AB_10601090, HPA036584: AB_10670803" "unprognostic (8.63e-2)" "unprognostic (2.36e-2)" "unprognostic (1.83e-2)" 0.9 2.2 0.4 1.0 1.4 0.3 0.8 1.0 1.9 1.5 0.8 0.8 0.6 0.4 0.0 1.8 1.3 0.2 3.0 0.3 1.6 0.4 0.5 0.9 1.0 1.3 0.7 0.6 0.8 0.4 0.1 0.7 0.9 0.5 0.2 10.1 1.8 2.7 6.4 0.7 0.8 0.3 0.4 0.9 1.1 6.7 1.3 2.0 0.4 2.3 1.5 1.0 0.8 2.0 2.1 6.4 3.9 0.2 2.5 2.3 0.4 0.9 1.3 1.4 5.8 7.8 1.2 1.9 0.8 3.0 5.1 1.1 2.8 2.2 1.3 23.3 2.4 5.4 1.5 0.0 1.7 0.6 3.0 2.9 3.2 3.3 0.1 4.3 1.6 8.3 1.4 2.8 0.8 0.0 12.7 0.9 0.4 3.9 2.1 1.7 3.1 1.7 0.5 1.9 0.4 2.7 5.5 1.1 0.2 1.4 0.0 4.7 6.8 2.3 3.9 1.3 0.7 4.9 0.9 3.5 1.2 23.8 0.0 7.4 2.1 3.0 3.4 2.4 3.7 7.5 3.2 4.1 2.2 7.3 2.4 1.8 0.7 4.9 1.3 0.3 6.5 4.9 0.4 1.4 1.0 1.9 0.3 1.6 1.3 0.7 0.9 0.4 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COMMD4 FLJ20452 ENSG00000140365 "COMM domain containing 4" Q9H0A8 15 75336020-75343224 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039935, HPA066957" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Vesicles, Plasma membrane" "HPA039935: , HPA066957: AB_2685754" "unprognostic (7.77e-2)" "unprognostic (3.07e-3)" "unprognostic (1.03e-1)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.49e-1)" "unprognostic (2.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.78e-3)" "unprognostic (2.01e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-3)" "unprognostic (2.51e-1)" "unprognostic (2.27e-1)" "unprognostic (1.96e-1)" "unprognostic (5.07e-2)" 36.2 72.3 38.8 33.5 39.4 52.9 36.8 40.5 50.4 31.1 43.7 41.6 48.3 30.3 30.2 39.9 34.6 37.3 38.9 36.9 39.7 54.6 51.0 34.6 44.7 39.5 38.1 24.4 33.8 48.9 33.9 31.2 38.6 34.2 33.8 13.4 43.4 34.0 30.3 35.0 42.2 24.7 40.8 41.3 42.5 81.2 42.4 53.3 38.8 15.3 36.7 33.6 31.8 42.0 138.2 222.5 97.5 124.8 42.3 64.9 98.5 98.8 106.2 191.2 196.6 133.8 184.0 88.8 100.2 79.5 168.8 144.8 175.2 116.5 82.7 70.1 242.4 104.8 169.8 151.0 76.4 79.4 111.0 74.3 63.6 116.2 21.9 48.4 96.5 103.6 108.2 128.1 147.1 179.7 71.0 117.4 140.9 75.2 127.9 127.5 137.4 127.8 98.6 127.8 79.2 114.8 131.2 105.1 169.8 63.8 164.7 160.9 78.6 135.3 119.2 125.8 184.8 93.4 218.7 101.4 138.9 181.9 125.4 27.0 44.1 40.7 84.7 61.8 52.8 47.5 51.7 63.2 50.0 46.4 31.9 47.4 9.5 76.8 55.6 70.6 87.6 39.4 38.8 39.4 40.5 50.4 36.9 39.7 39.5 38.1 38.6 40.8 42.4 42.0 43.7 28.9 52.4 15.0 26.2 27.0 44.8 58.5 28.5 40.7 44.3 50.3 18.7 38.6 46.2 35.0 31.3 80.9 34.8 59.6 58.7 72.6 12.2 37.1 44.9 42.7 30.5 60.8 9.0 78.7 107.0 43.4 33.1 45.7 41.8 91.1 37.5 41.9 127.5 16.8 8.8 72.8 44.7 35.8 27.0 17.6 49.0 41.3 37.4 11.2 28.5 78.1 53.5 7.1 17.6 72.4 61.7 34.3 43.0 26.6 71.2 98.1 39.8 49.4 46.0 36.1 59.3 152.9 63.5 34.3 30.7 50.8 32.2 53.4 58.7 48.7 COMMD9 "FLJ31106, HSPC166" ENSG00000110442 "COMM domain containing 9" Q9P000 11 36269284-36289449 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009142 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA009142: AB_1847105" "unprognostic (1.56e-2)" "unprognostic (4.75e-3)" "unprognostic (7.57e-2)" "unprognostic (4.40e-3)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-3)" "unprognostic (2.62e-1)" "unprognostic (6.15e-2)" "prognostic favorable (8.54e-4)" "unprognostic (4.94e-2)" "unprognostic (2.40e-1)" "unprognostic (6.08e-3)" "unprognostic (7.24e-2)" "unprognostic (1.71e-1)" "unprognostic (7.31e-3)" "unprognostic (1.88e-1)" 26.8 32.1 33.8 21.8 34.1 50.8 24.3 35.1 36.7 17.2 29.6 19.6 21.1 14.1 25.1 24.9 20.3 20.5 31.1 33.8 33.8 38.7 36.6 26.8 26.0 34.2 34.4 19.4 26.4 27.4 23.2 24.8 33.9 14.0 24.2 20.3 21.9 13.3 64.2 27.1 20.2 21.9 36.9 26.8 19.7 14.9 36.0 30.6 25.1 61.7 32.0 20.6 16.6 39.1 28.8 33.4 36.1 38.2 54.5 37.8 20.0 33.6 42.6 74.7 69.8 27.3 23.9 33.0 32.5 67.1 57.5 41.4 64.0 45.2 69.6 39.9 75.2 18.2 57.6 48.0 51.0 71.6 52.3 48.0 49.5 40.9 25.0 38.5 62.2 43.3 45.7 34.7 59.4 36.9 47.9 49.6 38.5 55.6 70.3 52.1 81.7 38.9 78.6 26.6 44.1 49.2 47.9 47.1 43.6 29.2 102.7 27.0 41.9 45.0 34.4 107.9 49.8 24.3 53.2 37.2 51.8 66.4 44.0 85.6 376.6 173.7 91.4 359.0 86.8 130.7 87.5 88.4 383.6 138.3 99.8 83.4 42.7 94.8 300.9 145.8 114.5 315.2 33.8 34.1 35.1 36.7 33.8 33.8 34.2 34.4 33.9 36.9 36.0 39.1 26.9 22.4 29.4 2.6 27.0 15.3 12.7 37.4 13.1 16.6 25.6 38.7 29.9 12.8 20.2 18.4 10.4 43.2 28.3 16.9 78.2 70.1 9.5 13.2 20.3 22.8 25.7 23.1 9.4 46.4 52.9 21.2 11.7 17.0 19.0 25.6 15.4 17.1 105.1 5.0 8.7 20.4 34.6 59.5 35.6 28.9 17.7 57.5 24.9 1.9 61.3 36.3 33.0 4.5 8.8 46.5 17.7 11.7 10.4 4.9 30.3 62.5 8.5 22.9 13.1 12.3 22.8 32.8 33.3 19.6 21.6 24.9 19.2 28.4 24.6 12.0 COMTD1 FLJ23841 ENSG00000165644 "Catechol-O-methyltransferase domain containing 1" Q86VU5 10 75233641-75236030 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 128.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 334.8;Exocrine glandular cells: 249.5;Paneth cells: 272.5;Proximal enterocytes: 435.9;Squamous epithelial cells: 285.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.2;PC-3: 38.3;RPMI-8226: 24.5;U-266/70: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042165 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA042165: AB_10794042" "unprognostic (2.53e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (9.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (8.08e-3)" "unprognostic (9.35e-2)" "unprognostic (6.74e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" 11.0 17.9 1.1 1.0 1.5 1.5 9.8 1.2 1.8 18.3 5.8 23.3 7.4 7.5 0.4 70.6 7.2 0.4 33.5 1.3 1.7 29.1 37.5 11.7 0.6 1.7 2.0 8.0 128.6 3.4 17.1 0.9 1.7 11.8 1.0 1.1 23.9 1.0 28.2 25.3 25.2 0.5 1.1 12.4 27.8 3.4 1.6 0.5 18.5 0.7 0.7 8.3 29.0 0.9 6.9 2.2 0.5 1.3 0.1 0.7 19.0 2.1 1.0 0.3 0.6 1.6 6.0 20.0 3.5 0.4 1.1 9.0 0.9 1.9 0.1 3.2 30.2 0.8 4.8 3.3 1.1 3.5 3.3 0.6 3.2 0.1 2.9 1.3 0.3 3.6 7.8 4.7 0.1 6.2 5.3 11.0 1.2 5.1 38.3 10.6 1.3 24.5 1.8 0.6 8.4 2.3 2.4 16.0 4.8 0.5 8.9 0.5 1.4 0.6 5.9 1.2 2.1 21.5 4.5 9.8 0.7 3.4 0.6 0.0 7.1 3.9 10.6 10.0 11.6 7.1 10.6 11.0 8.5 5.6 3.5 6.1 1.4 7.3 9.4 15.3 8.9 6.8 1.1 1.5 1.2 1.8 1.3 1.7 1.7 2.0 1.7 1.1 1.6 0.9 23.6 19.2 11.5 1.6 18.2 29.4 40.5 54.1 133.1 6.0 29.3 37.1 31.1 57.2 33.8 53.3 10.4 33.4 30.8 334.8 144.8 162.8 1.6 10.5 7.7 13.5 40.2 16.0 3.4 249.5 79.1 13.4 148.8 33.4 12.7 10.3 25.4 84.0 35.1 1.7 3.9 206.0 42.7 24.2 21.3 3.5 9.6 21.8 37.4 6.5 31.8 10.7 24.7 1.5 0.5 109.2 272.5 7.2 50.8 38.7 435.9 140.3 11.3 34.5 32.9 6.2 25.6 2.6 3.4 285.3 38.2 30.4 29.2 10.7 143.8 56.7 COPA HEP-COP ENSG00000122218 "COPI coat complex subunit alpha" P53621 1 160288594-160343273 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028024 Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA 150000 "Cluster 18: Basophils - Vesicular transport" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA028024: AB_10603787" "unprognostic (1.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.77e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.42e-2)" "unprognostic (3.14e-1)" "unprognostic (2.21e-1)" "unprognostic (5.03e-2)" "unprognostic (3.10e-1)" "unprognostic (2.05e-2)" "unprognostic (8.70e-2)" "unprognostic (2.03e-1)" "unprognostic (4.94e-2)" "unprognostic (1.39e-1)" 47.7 43.1 46.6 38.5 48.9 30.0 42.0 57.2 57.1 52.9 67.4 42.3 53.7 46.7 55.1 38.3 41.2 38.6 55.1 48.6 53.7 48.6 55.0 47.0 36.1 57.9 51.0 46.9 49.9 51.8 59.8 48.3 60.0 43.5 47.9 26.2 57.6 39.4 59.1 40.0 49.0 50.0 53.9 42.7 43.5 24.4 51.1 37.6 60.1 38.2 38.9 41.3 37.9 66.4 91.0 68.5 70.1 66.9 164.9 154.7 78.6 116.5 144.3 103.1 138.7 72.0 60.5 64.4 73.3 194.0 57.7 86.0 92.0 81.3 126.5 68.6 64.3 76.8 95.2 79.0 115.1 94.1 74.5 134.8 49.1 140.0 128.9 126.3 126.4 64.4 71.9 69.7 124.4 43.6 49.3 53.3 80.1 97.3 79.0 49.2 89.2 118.9 94.3 94.7 62.1 84.3 157.3 109.2 148.0 115.0 140.4 133.9 162.8 84.3 54.1 108.2 80.2 106.8 76.3 106.6 104.2 51.3 122.8 48.1 39.0 25.4 18.6 36.7 25.5 17.8 16.7 21.3 40.4 14.2 14.3 17.9 10.9 26.7 36.2 17.8 22.9 35.5 46.6 48.9 57.2 57.1 48.6 53.7 57.9 51.0 60.0 53.9 51.1 66.4 53.6 76.9 54.7 44.7 66.4 28.2 35.5 41.6 29.6 52.4 53.0 41.3 51.8 42.9 49.7 40.5 81.3 41.0 83.2 66.8 13.7 49.9 14.7 50.7 68.1 50.4 55.3 37.0 77.6 49.6 63.3 66.2 65.2 64.3 45.6 63.0 52.8 71.1 51.2 45.4 73.8 83.8 30.5 93.7 58.0 6.4 71.1 84.3 26.6 67.5 75.0 41.0 38.1 65.9 178.9 55.5 48.1 56.8 115.9 52.9 98.9 41.4 66.2 53.7 39.5 57.6 52.4 37.6 25.7 35.8 31.8 69.2 58.3 58.1 66.6 61.2 COPB1 COPB ENSG00000129083 "COPI coat complex subunit beta 1" P53618 11 14443440-14500027 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012338, HPA043954, HPA064403" Supported Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 330000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "CAB012338: AB_726922, HPA043954: AB_2678746, HPA064403: AB_2685258" "unprognostic (2.35e-1)" "unprognostic (1.02e-3)" "unprognostic (1.36e-2)" "unprognostic (4.76e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.91e-4)" "prognostic unfavorable (5.63e-7)" "unprognostic (4.69e-3)" "unprognostic (3.42e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (8.94e-2)" "unprognostic (1.78e-2)" "unprognostic (3.02e-2)" "unprognostic (8.00e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" 48.1 47.1 19.9 55.0 21.8 79.8 62.6 26.2 25.3 64.9 44.7 59.8 57.7 52.6 69.3 46.7 49.2 54.9 43.7 20.1 23.6 65.3 73.6 49.9 59.1 24.2 21.8 49.1 59.2 67.6 48.4 69.2 23.7 66.9 67.1 39.3 67.5 53.8 33.1 36.6 58.8 61.1 23.5 46.3 59.7 46.8 23.0 68.1 81.0 38.1 64.5 60.4 40.0 27.6 134.9 113.6 118.6 89.4 193.1 221.3 95.9 199.2 206.5 173.1 202.0 89.1 203.5 130.1 87.1 252.9 164.6 144.7 134.6 133.3 212.1 122.7 114.0 138.3 74.3 135.8 171.3 128.9 134.4 156.3 172.4 116.0 217.8 158.9 183.7 71.6 104.5 103.8 221.1 101.6 117.2 78.7 61.7 163.3 123.1 94.9 163.1 89.0 156.1 123.3 75.6 81.2 154.2 123.2 104.8 135.5 112.3 110.1 189.5 166.2 85.4 181.3 110.1 55.2 100.5 143.8 125.1 79.2 158.6 52.8 38.7 43.5 45.7 47.8 55.7 38.4 38.1 47.6 52.3 32.0 37.8 39.8 31.2 44.6 49.8 31.1 44.8 43.2 19.9 21.8 26.2 25.3 20.1 23.6 24.2 21.8 23.7 23.5 23.0 27.6 55.6 109.0 63.2 29.0 64.3 38.9 59.7 82.6 52.3 28.4 43.0 27.9 31.3 35.8 107.8 44.1 27.1 65.4 71.2 55.9 41.1 77.1 17.2 72.6 81.4 55.5 43.8 50.9 36.9 81.7 69.6 70.5 63.2 72.5 65.2 50.7 51.4 58.1 60.9 18.5 39.1 87.5 61.1 50.7 43.5 10.7 51.0 61.5 21.4 35.6 70.1 34.0 44.3 32.6 49.6 93.6 37.5 55.3 107.4 54.3 60.6 57.3 131.9 29.5 52.6 60.8 78.7 87.5 64.3 48.7 35.8 117.0 77.0 49.3 51.5 60.7 COPG1 COPG ENSG00000181789 "COPI coat complex subunit gamma 1" Q9Y678 3 129249606-129277773 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037866, HPA037867, HPA045712" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No 57000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA037866: AB_2675710, HPA037867: AB_10697085, HPA045712: AB_2679428" "unprognostic (8.86e-2)" "unprognostic (2.22e-2)" "unprognostic (4.22e-3)" "unprognostic (1.15e-1)" "unprognostic (1.81e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (1.22e-6)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (5.64e-2)" "unprognostic (8.90e-3)" "unprognostic (3.29e-1)" "unprognostic (1.23e-3)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (2.99e-1)" "unprognostic (1.60e-1)" 84.7 111.0 66.6 59.0 68.2 59.4 79.8 69.5 80.7 100.4 93.0 107.6 86.7 75.5 157.4 86.8 70.0 53.8 95.5 70.3 73.7 82.7 149.5 84.4 54.8 74.3 71.5 77.9 162.4 96.3 139.0 81.9 77.4 107.7 109.8 33.4 130.7 72.7 75.7 74.4 86.7 72.2 66.4 81.9 114.0 46.5 73.2 53.5 83.3 43.2 67.1 67.2 72.2 73.2 167.8 83.2 119.1 104.0 272.8 219.0 126.9 266.3 251.8 179.5 225.2 153.9 101.2 91.1 150.8 380.7 145.6 98.4 99.5 157.2 193.6 112.0 41.4 151.9 103.2 252.6 247.9 116.4 156.4 230.9 135.6 143.8 235.0 196.1 164.3 68.9 54.2 213.6 219.2 253.4 68.7 117.7 71.3 243.6 100.9 73.3 111.8 178.3 227.3 136.7 74.1 86.1 204.2 150.3 255.9 129.8 167.1 167.6 223.9 96.9 91.7 207.2 104.2 165.7 86.1 158.9 236.4 86.9 190.0 79.1 49.9 37.2 44.1 59.2 53.6 24.9 39.8 43.9 57.0 26.9 30.0 36.2 37.2 57.0 57.3 52.2 43.8 56.2 66.6 68.2 69.5 80.7 70.3 73.7 74.3 71.5 77.4 66.4 73.2 73.2 16.6 16.0 31.5 7.8 19.2 8.8 16.9 35.4 12.0 9.2 18.9 8.6 23.3 17.2 34.6 27.6 4.2 55.6 19.7 77.0 43.0 44.5 10.4 26.2 27.7 22.8 38.6 22.9 14.1 46.5 63.1 32.5 53.0 36.9 15.2 28.6 28.9 56.5 39.0 5.0 14.8 75.1 22.4 31.2 14.8 4.7 41.0 21.6 23.2 7.5 36.5 12.7 18.6 4.5 11.8 40.8 44.6 31.2 68.4 24.4 64.5 39.5 32.6 7.1 19.7 20.2 33.3 24.3 17.0 16.4 10.2 72.2 19.4 27.7 44.6 20.6 COPRS "C17orf79, COPR5, HSA272196, TTP1" ENSG00000172301 "Coordinator of PRMT5 and differentiation stimulator" Q9NQ92 17 31851871-31859291 "Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 253.2;Late spermatids: 288.9;Spermatocytes: 575.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052552 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA052552: AB_2681868" "unprognostic (1.65e-2)" "unprognostic (4.88e-2)" "unprognostic (2.46e-1)" "unprognostic (4.01e-3)" "unprognostic (3.12e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (3.69e-4)" "unprognostic (6.88e-2)" "unprognostic (3.10e-1)" "unprognostic (4.44e-2)" "unprognostic (5.28e-3)" "unprognostic (1.01e-2)" "unprognostic (1.19e-3)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (3.11e-2)" 51.1 46.5 127.4 20.1 130.0 14.2 49.8 124.6 172.8 42.8 129.5 99.0 16.0 43.4 117.6 26.4 51.7 32.0 66.1 128.7 136.2 55.8 68.1 33.9 21.0 123.6 126.7 51.7 41.9 49.0 67.4 19.7 128.8 60.2 27.4 56.0 35.4 46.3 53.5 30.3 31.1 44.4 123.3 25.1 51.6 241.4 131.2 13.2 63.2 53.3 27.8 57.1 33.3 124.1 101.5 132.9 64.4 66.6 104.3 99.5 45.2 109.7 140.3 125.8 127.8 83.4 27.0 53.0 58.8 135.1 245.0 58.5 116.0 67.6 142.3 18.7 153.8 15.4 79.7 99.5 105.5 53.2 43.4 64.2 87.4 169.3 92.4 135.7 68.6 75.2 75.0 46.9 139.6 89.9 79.6 170.7 49.1 65.2 62.8 61.8 120.8 104.4 74.5 62.8 58.4 44.2 65.9 32.6 107.1 56.1 104.4 57.9 37.0 327.8 85.9 116.6 156.3 76.2 77.2 58.3 170.8 50.1 44.9 1.8 2.0 0.0 0.6 2.0 1.6 1.9 0.5 0.1 2.6 3.6 0.3 0.3 0.6 0.0 0.9 1.0 0.8 0.3 127.4 130.0 124.6 172.8 128.7 136.2 123.6 126.7 128.8 123.3 131.2 124.1 54.2 22.4 8.3 13.7 20.9 34.4 69.0 15.3 29.6 43.1 79.2 88.4 78.9 68.6 13.4 86.5 10.4 31.9 10.7 12.1 225.0 99.6 253.2 142.2 38.5 53.5 19.7 18.7 14.6 80.8 54.9 65.7 14.3 40.5 3.8 39.9 62.4 95.4 87.6 26.9 14.8 15.9 40.7 30.3 34.7 288.9 62.4 36.5 58.7 7.5 47.9 136.3 9.2 3.5 9.2 70.7 8.4 65.1 27.4 127.4 6.4 212.0 55.8 43.0 19.7 46.9 63.5 575.6 63.8 21.4 31.7 27.4 11.2 49.6 21.3 39.6 COQ10A FLJ32452 ENSG00000135469 "Coenzyme Q10A" Q96MF6 12 56266890-56270966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 166.3;skeletal muscle: 280.7;tongue: 387.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068931 Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 24: NB-4 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Endoplasmic reticulum, Golgi apparatus" "HPA068931: AB_2686061" "unprognostic (4.55e-2)" "unprognostic (4.88e-3)" "prognostic unfavorable (5.46e-4)" "unprognostic (8.99e-3)" "unprognostic (2.77e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-1)" "unprognostic (2.86e-3)" "unprognostic (6.09e-2)" "unprognostic (8.57e-2)" "prognostic favorable (2.06e-4)" "unprognostic (5.03e-2)" "prognostic favorable (3.44e-4)" "unprognostic (1.67e-1)" "unprognostic (8.07e-2)" "unprognostic (7.20e-2)" "unprognostic (1.15e-1)" 7.0 33.3 16.3 3.5 16.9 4.6 7.2 17.7 19.7 9.1 21.1 9.5 3.2 10.0 16.2 9.0 10.8 6.3 166.3 16.2 17.6 17.1 37.0 6.7 7.8 16.5 18.3 10.2 18.0 15.7 25.4 2.7 17.2 11.9 5.0 26.0 12.6 9.8 280.7 5.0 9.7 7.2 16.4 12.2 8.8 6.8 18.6 7.9 10.3 387.5 8.9 8.5 6.8 15.8 3.7 15.2 14.4 9.4 8.1 8.0 6.0 5.2 12.5 18.3 18.2 11.9 5.6 21.5 11.3 13.3 5.1 3.5 16.8 3.0 10.9 3.2 17.0 10.2 14.1 12.4 11.0 8.1 5.9 8.4 4.9 13.6 5.3 11.4 9.8 14.9 6.8 8.8 17.1 5.1 11.7 29.1 12.0 2.7 8.7 24.2 15.6 14.5 10.1 2.2 20.5 22.0 18.1 3.8 5.8 10.6 5.8 8.9 6.9 3.4 10.0 9.5 5.3 18.1 20.4 10.8 10.2 7.6 2.6 14.1 1.1 1.1 7.4 1.0 7.4 12.7 7.0 7.8 1.7 6.8 8.3 8.1 0.4 5.8 0.9 6.9 5.1 3.9 16.3 16.9 17.7 19.7 16.2 17.6 16.5 18.3 17.2 16.4 18.6 15.8 8.1 3.2 7.2 12.4 20.8 13.4 13.0 2.3 15.4 17.9 8.4 12.7 120.5 7.2 3.2 11.0 16.7 5.8 32.0 2.0 52.8 2.8 0.2 13.7 6.3 9.6 16.2 4.2 3.9 4.6 6.8 10.9 6.6 5.1 4.5 8.2 3.6 15.2 5.2 32.0 6.2 3.4 4.1 2.5 12.1 1.7 8.4 4.5 12.4 3.7 2.5 26.5 13.4 4.5 2.3 2.7 2.5 17.0 18.6 4.4 3.1 18.1 11.0 32.3 39.5 22.1 14.0 4.0 22.2 4.9 10.5 3.0 19.5 10.4 4.4 5.9 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CORO7-PAM16 ENSG00000103426 "CORO7-PAM16 readthrough" 16 4340251-4420494 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Club cells: 2.5;Oligodendrocytes: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041657, HPA053586, HPA062721" Uncertain Approved Nucleoplasm,Microtubules,Mitochondria NA NA "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Mitochondria" Microtubules "HPA041657: AB_10796351, HPA053586: AB_2682201, HPA062721: AB_2684849" "unprognostic (2.95e-2)" "unprognostic (2.46e-1)" "unprognostic (1.44e-1)" "unprognostic (2.46e-1)" "unprognostic (2.11e-1)" "unprognostic (1.24e-2)" "unprognostic (2.11e-4)" "unprognostic (4.39e-2)" "unprognostic (9.83e-3)" "unprognostic (1.20e-1)" "unprognostic (8.75e-3)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.79e-2)" "unprognostic (2.59e-2)" "unprognostic (2.19e-1)" "unprognostic (3.85e-1)" 0.1 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.3 0.2 0.5 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COX10 ENSG00000006695 "Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10" Q12887 17 14069490-14231736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Heme biosynthesis" Transferase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 44.5;tongue: 44.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 88.2;Late spermatids: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032005, HPA032006" Supported Supported Nucleoli,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Nucleoli, Cytosol" "HPA032005: AB_10603560, HPA032006: AB_10670554" "unprognostic (6.17e-2)" "unprognostic (3.14e-1)" "unprognostic (1.41e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.40e-2)" "unprognostic (6.27e-3)" "unprognostic (1.07e-1)" "unprognostic (9.46e-3)" "unprognostic (6.46e-2)" "prognostic favorable (4.32e-6)" "prognostic favorable (8.73e-4)" "unprognostic (8.82e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-2)" 7.1 7.5 3.1 5.4 2.9 10.4 6.0 4.1 4.4 5.8 4.3 12.5 12.5 5.2 4.4 10.9 5.6 4.2 27.9 3.3 3.9 11.6 10.6 4.4 5.8 3.8 3.5 4.5 9.9 9.6 3.3 7.0 3.5 5.6 12.3 5.6 7.2 5.5 44.5 7.4 10.1 7.2 3.0 4.8 9.3 21.1 4.0 5.4 6.2 44.3 7.5 8.5 6.6 3.6 10.1 19.7 7.7 11.9 7.7 5.6 19.5 12.3 8.4 21.9 14.6 16.3 6.6 23.5 9.8 13.0 6.8 20.2 16.6 16.3 17.3 13.1 15.7 14.5 12.4 20.0 14.2 15.5 12.3 9.8 19.5 14.0 17.6 7.9 11.4 15.8 20.4 8.2 9.5 13.1 13.5 10.5 12.8 37.6 9.5 10.3 28.8 18.5 15.2 20.1 5.2 9.8 12.0 18.5 16.5 36.1 9.6 9.2 9.9 8.9 8.0 9.9 15.8 10.1 15.6 11.2 14.9 15.7 11.9 3.8 11.3 4.4 9.8 16.1 10.6 13.2 11.3 10.5 14.9 9.2 11.9 11.5 1.2 10.0 13.9 4.6 20.1 11.0 3.1 2.9 4.1 4.4 3.3 3.9 3.8 3.5 3.5 3.0 4.0 3.6 5.9 0.0 14.7 25.8 9.6 9.7 9.5 9.8 14.2 7.5 8.7 7.4 88.2 5.7 7.3 11.0 10.4 19.7 5.7 13.8 41.1 9.1 41.1 9.6 9.6 7.8 12.6 13.3 33.5 8.7 17.5 8.8 16.3 9.4 5.1 7.5 3.9 9.6 10.8 0.0 43.0 16.4 8.2 4.4 4.7 81.0 2.1 6.7 5.4 22.5 6.3 4.6 8.2 34.7 26.9 8.8 11.4 6.8 12.5 8.7 26.6 17.8 5.8 12.2 0.0 5.2 12.5 22.8 19.2 19.4 10.4 16.1 8.6 6.6 18.9 13.7 COX6B2 "COXVIB2, CT59, FLJ32865" ENSG00000160471 "Cytochrome c oxidase subunit 6B2" Q6YFQ2 19 55349306-55354719 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 90.5" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Late spermatids: 27.4;Respiratory ciliated cells: 12.6;Spermatocytes: 61.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "CAPAN-2: 24.9;SCLC-21H: 10.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA035014 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA035014: AB_10601261" "unprognostic (7.43e-3)" "unprognostic (8.72e-2)" "unprognostic (1.42e-1)" "unprognostic (5.75e-2)" "unprognostic (2.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (6.45e-3)" "unprognostic (1.02e-1)" "unprognostic (6.82e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (8.11e-2)" "unprognostic (1.81e-6)" "unprognostic (9.91e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (2.02e-1)" 0.7 0.1 0.3 1.0 0.2 1.1 0.9 1.0 0.5 0.4 0.4 6.7 0.2 0.2 1.2 1.2 0.7 0.2 0.1 0.3 0.3 0.8 0.1 0.3 0.2 0.3 0.5 0.5 0.2 0.0 0.9 0.2 0.4 0.7 4.8 0.4 1.4 0.2 0.3 2.5 0.3 0.2 0.1 0.3 0.2 90.5 0.3 3.3 0.1 0.0 1.9 0.5 0.9 0.6 3.1 0.4 0.1 0.1 0.0 0.0 0.2 0.4 0.1 0.3 0.5 0.2 24.9 0.1 0.2 0.3 0.3 1.8 0.7 0.2 0.2 0.9 0.7 0.0 2.0 0.1 0.3 0.2 1.8 0.2 2.7 0.5 0.6 1.7 0.0 0.1 0.4 0.2 0.0 0.6 0.1 0.2 0.6 2.6 0.5 0.1 0.0 0.2 0.1 0.4 10.1 0.3 0.4 0.1 0.0 0.6 0.4 0.0 0.5 0.2 0.5 0.1 0.3 1.6 1.4 0.1 0.1 0.3 0.1 0.8 0.2 0.3 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.2 0.2 1.5 0.5 0.2 0.4 0.2 0.3 0.3 0.2 1.0 0.5 0.3 0.3 0.3 0.5 0.4 0.1 0.3 0.6 0.2 0.0 0.5 0.0 0.0 0.5 0.7 3.5 1.2 2.4 0.9 1.3 0.6 0.0 2.1 0.0 4.2 0.5 1.8 8.0 0.0 0.5 36.0 1.3 0.5 0.2 1.2 0.0 0.0 0.6 0.3 0.6 0.0 0.8 0.0 0.2 0.0 0.0 0.1 3.3 0.1 1.3 4.1 0.0 0.0 27.4 0.6 0.3 0.0 0.0 0.0 1.4 2.1 0.0 0.1 9.6 4.1 0.0 0.3 0.7 3.4 0.1 12.6 5.4 0.0 0.4 0.5 61.1 1.7 0.3 0.4 0.4 0.6 0.1 6.5 2.3 CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.6;skin 1: 57.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.7;Basal respiratory cells: 23.7;Exocrine glandular cells: 54.1;Fibroblasts: 11.5;Suprabasal keratinocytes: 31.0" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 140.1;hTERT-RPE1: 261.0;LHCN-M2: 284.2;U-2 OS: 151.0;U-87 MG: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved Nucleoplasm,Centrosome,Cytosol "Secreted in other tissues" NA Yes 390000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Centrosome, Cytosol" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" 5.0 4.4 0.4 0.4 0.4 0.1 3.5 0.5 1.7 15.3 0.5 0.0 0.0 0.2 0.3 21.6 0.4 0.1 1.1 0.6 2.1 0.6 0.1 0.4 0.2 1.1 0.7 0.1 12.7 0.0 0.5 2.0 1.1 0.2 0.0 0.2 6.7 0.0 0.3 57.1 0.2 0.8 0.6 3.3 0.4 0.3 1.2 0.8 0.0 0.0 0.9 0.0 12.6 1.1 95.3 5.0 0.3 0.3 0.7 1.5 0.1 74.6 140.1 74.9 18.5 0.7 8.1 0.1 14.3 31.9 75.2 5.5 0.0 41.3 76.7 0.4 0.3 0.0 33.3 2.1 1.8 0.3 0.2 1.0 65.2 6.7 9.4 261.0 0.3 0.1 0.0 0.2 284.2 0.2 0.0 0.0 0.8 0.4 11.1 0.3 75.4 0.1 34.5 4.0 0.2 0.0 49.9 23.3 0.5 28.0 0.5 0.4 57.3 18.1 151.0 6.2 7.4 0.2 0.2 0.1 272.7 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.7 0.6 2.1 1.1 0.7 1.1 0.6 1.2 1.1 0.0 3.2 0.5 0.0 0.0 17.7 0.5 23.7 0.6 0.0 4.2 2.8 0.3 0.0 8.5 0.0 0.0 5.6 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.3 0.0 0.0 0.4 54.1 1.2 11.5 0.0 2.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.2 0.0 0.3 3.6 1.0 0.6 0.0 0.0 0.0 0.5 7.9 0.0 0.0 0.0 0.9 0.0 0.1 2.9 0.0 0.0 1.3 0.4 0.1 0.7 10.0 31.0 9.4 0.1 0.0 0.0 1.6 CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378927-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052796, HPA055465" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear speckles" NA NA 1700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nuclear speckles" "Nuclear membrane" "HPA052796: AB_2681953, HPA055465: AB_2682823" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" 25.9 7.4 10.8 19.7 13.1 32.2 20.5 15.4 25.6 40.9 9.4 18.0 20.3 15.8 13.2 12.1 23.0 31.8 9.1 11.8 13.0 19.7 25.4 18.2 7.9 19.5 13.3 7.8 15.7 28.5 6.1 30.3 17.8 16.8 20.1 14.9 44.8 11.2 8.1 8.2 19.8 23.3 18.3 9.3 37.3 41.3 13.5 8.3 57.6 14.0 9.9 18.3 7.1 28.0 39.4 58.9 50.0 51.6 51.0 95.9 18.0 53.1 77.2 36.0 43.9 69.6 24.9 5.1 65.8 61.3 45.6 27.6 32.7 67.1 60.3 18.7 46.7 11.2 32.5 43.2 61.8 73.8 28.3 172.3 29.4 46.2 44.3 59.7 74.3 16.5 22.1 56.1 29.2 7.7 23.9 20.3 14.1 89.8 13.4 22.6 57.8 15.3 67.3 44.2 12.5 31.5 63.4 54.0 27.6 58.0 51.2 50.4 89.2 35.7 23.3 56.2 51.3 22.5 50.0 16.1 45.6 47.2 30.9 4.5 7.7 8.4 4.1 3.6 4.5 0.2 2.1 3.5 4.4 0.4 1.6 2.0 25.0 2.7 3.2 0.5 1.5 3.6 10.8 13.1 15.4 25.6 11.8 13.0 19.5 13.3 17.8 18.3 13.5 28.0 124.4 32.1 23.9 28.4 7.5 22.0 34.2 99.2 21.6 30.8 34.9 18.8 13.7 155.8 129.5 29.5 45.9 24.8 35.9 37.8 1.9 32.4 96.1 21.9 24.9 51.9 32.3 15.6 62.9 24.8 11.1 25.6 72.4 35.2 24.1 21.6 56.0 93.9 15.9 47.1 57.1 69.0 85.5 31.2 20.4 56.0 16.8 33.7 30.2 90.9 32.9 13.4 29.9 45.8 164.5 32.8 26.4 16.1 38.1 58.5 50.1 18.5 84.2 33.8 0.0 21.3 23.4 31.0 21.0 21.1 18.6 24.1 35.6 14.2 34.4 50.7 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CPEB4 KIAA1673 ENSG00000113742 "Cytoplasmic polyadenylation element binding protein 4" Q17RY0 5 173888349-173961980 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 322.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/70: 112.1;U-266/84: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038394 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Golgi apparatus" Vesicles "HPA038394: AB_10671226" "unprognostic (2.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.12e-1)" "unprognostic (3.99e-1)" "unprognostic (8.80e-2)" "unprognostic (2.91e-1)" "unprognostic (4.58e-1)" "unprognostic (8.75e-2)" "unprognostic (2.54e-1)" "unprognostic (9.37e-3)" "unprognostic (1.44e-1)" "unprognostic (7.84e-2)" "prognostic favorable (4.99e-8)" "unprognostic (2.66e-1)" "unprognostic (4.73e-2)" "unprognostic (1.42e-2)" "unprognostic (3.83e-2)" 20.0 66.2 22.4 17.8 29.4 72.0 17.3 44.7 29.3 17.4 44.2 12.8 13.7 12.7 6.9 30.8 10.4 20.0 46.6 23.7 24.8 50.7 79.1 16.6 12.5 20.6 27.8 10.7 36.6 73.1 12.3 18.3 22.7 12.2 13.0 41.7 23.0 15.4 62.1 12.0 15.1 16.3 23.0 14.7 19.2 15.7 26.3 9.4 33.4 62.5 16.3 22.2 8.8 32.4 12.6 18.4 9.2 5.4 14.0 8.5 16.0 21.5 20.2 7.6 9.3 16.1 8.5 15.9 16.0 12.0 24.5 1.0 7.4 12.6 12.0 32.3 8.4 11.0 42.2 10.9 30.5 4.5 19.4 13.2 24.9 19.6 29.3 32.5 8.5 6.7 33.8 35.5 17.6 8.8 3.7 3.5 4.8 5.3 17.9 3.5 8.5 50.7 10.8 21.6 9.8 10.6 2.5 29.6 39.0 13.7 20.9 7.7 22.6 12.8 6.9 6.5 15.1 112.1 173.8 8.6 28.8 8.1 15.9 0.4 1.1 1.2 0.7 1.1 1.0 1.2 0.9 0.6 0.5 0.9 0.9 0.5 5.7 0.5 1.5 0.5 0.9 0.6 22.4 29.4 44.7 29.3 23.7 24.8 20.6 27.8 22.7 23.0 26.3 32.4 66.1 76.9 34.3 270.3 39.6 42.4 14.0 23.0 23.3 163.8 80.2 30.0 221.8 97.2 55.2 53.3 135.5 11.5 36.9 68.2 23.5 31.5 67.6 104.4 38.6 54.3 62.7 244.4 190.4 26.5 5.8 26.1 59.1 133.7 90.0 7.6 59.6 144.1 69.2 146.4 163.2 26.8 52.9 109.9 95.8 47.8 8.7 87.5 74.7 61.8 50.8 108.6 18.6 322.2 237.5 43.8 59.4 21.4 174.8 43.3 39.4 81.5 74.9 131.3 0.0 49.2 47.7 55.9 19.9 45.6 51.3 62.0 26.9 36.6 21.3 64.4 CPNE2 CPN2 ENSG00000140848 "Copine 2" Q96FN4 16 57092583-57148369 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.4" "Cell type enhanced" "Detected in many" "Adipocytes: 84.3;Hepatic stellate cells: 82.8;Oligodendrocytes: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041132 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA041132: AB_2677316" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (4.93e-3)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (2.10e-2)" "unprognostic (9.14e-2)" "unprognostic (2.10e-3)" "unprognostic (8.78e-3)" "unprognostic (2.18e-2)" "unprognostic (1.88e-1)" "unprognostic (3.53e-3)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" 35.1 7.3 34.5 12.8 50.2 60.6 24.9 41.1 45.3 36.5 36.9 29.2 6.0 20.7 6.6 15.9 28.0 14.3 15.5 36.7 46.6 14.1 9.4 37.2 11.0 52.9 48.1 10.7 7.3 10.9 7.5 27.9 48.6 14.0 28.3 1.7 10.9 17.1 11.7 11.7 21.2 25.1 39.3 18.2 9.2 16.4 61.0 6.3 15.9 13.5 9.2 16.7 18.5 87.4 23.9 45.1 68.0 38.1 12.0 11.6 11.3 25.4 39.8 56.8 39.5 12.7 27.0 14.2 22.7 38.6 31.4 36.7 27.1 15.1 30.6 17.7 15.9 5.9 17.5 10.7 21.6 4.8 0.6 11.1 16.8 22.3 10.8 42.4 84.5 7.6 16.0 0.5 14.5 11.1 7.2 69.9 15.5 11.6 9.5 88.8 21.3 11.9 37.7 9.0 1.4 27.6 32.3 6.9 19.4 30.5 7.5 94.4 60.3 51.6 27.7 13.1 33.5 3.4 3.0 31.8 33.4 20.6 37.0 0.0 1.5 0.8 0.2 0.4 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.2 1.5 0.1 0.1 0.0 0.2 0.4 34.5 50.2 41.1 45.3 36.7 46.6 52.9 48.1 48.6 39.3 61.0 87.4 84.3 19.2 7.4 8.1 1.5 2.3 17.1 6.0 7.4 0.4 8.2 6.9 2.3 4.3 5.1 5.5 0.0 0.6 1.4 43.4 5.9 4.7 19.9 33.4 13.8 41.0 3.6 0.8 1.0 4.2 2.9 12.3 1.5 39.3 0.0 26.7 82.8 2.0 23.6 0.0 7.4 13.7 4.1 25.3 7.4 5.9 6.8 12.0 7.2 8.4 10.7 3.6 0.0 17.1 86.3 6.2 25.1 7.5 0.8 14.2 35.4 2.6 9.2 0.0 32.9 9.3 21.7 0.6 2.6 6.2 4.3 0.8 8.4 2.1 18.2 16.3 CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196792-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 85.1;Hepatocytes: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" Nucleoli "HPA028201: AB_10599177, HPA028202: AB_10599942, HPA028214: AB_10601958" "unprognostic (2.43e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.27e-4)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (6.48e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.97e-2)" "prognostic favorable (1.46e-12)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-2)" 12.9 14.3 6.6 9.4 8.2 5.4 13.6 7.9 7.3 10.3 16.8 35.4 32.4 6.8 10.5 14.2 10.5 9.5 19.5 6.1 7.1 35.1 91.2 11.5 10.6 8.1 7.5 10.2 21.7 27.3 6.7 18.0 8.0 12.2 32.8 7.1 14.6 11.7 17.3 6.7 24.9 11.4 7.7 8.7 18.4 12.9 9.0 10.2 12.5 33.1 13.2 11.1 4.5 8.9 16.0 8.3 17.2 17.8 14.6 11.3 17.5 9.8 13.2 17.5 17.5 8.6 14.5 28.9 14.6 9.2 20.1 19.1 35.1 25.1 15.1 17.0 16.0 21.8 9.9 6.4 25.9 15.9 19.5 23.0 23.2 13.8 11.1 18.6 15.4 26.5 20.9 9.9 13.1 12.8 10.7 13.0 29.8 38.4 20.0 13.2 16.2 34.4 22.9 22.0 25.3 14.4 22.1 30.3 39.7 36.6 32.3 32.2 8.7 8.4 6.1 16.5 8.5 26.3 19.8 16.2 11.6 20.6 12.4 5.6 14.1 14.6 7.2 20.0 8.1 5.3 6.3 8.4 17.9 7.4 10.5 7.2 5.3 6.9 20.5 8.9 9.9 10.3 6.6 8.2 7.9 7.3 6.1 7.1 8.1 7.5 8.0 7.7 9.0 8.9 5.0 12.8 24.1 4.2 7.8 1.8 5.2 20.5 5.2 6.0 7.5 7.0 18.1 15.7 11.4 11.0 14.6 85.1 4.5 49.3 25.4 12.9 1.1 10.9 8.1 5.9 14.5 9.4 1.5 10.5 20.3 7.2 18.3 10.3 2.5 12.7 8.9 88.8 26.3 15.2 2.0 26.6 16.2 15.1 7.2 2.8 6.8 10.5 7.2 1.9 20.2 11.6 6.2 2.5 4.5 10.5 25.6 5.3 9.1 4.9 38.6 41.0 7.6 11.0 6.6 7.5 8.4 49.9 31.3 13.8 2.6 54.6 6.9 25.6 29.5 5.7 CRACDL "C2orf55, KIAA1211L, MGC42367" ENSG00000196872 "CRACD like" Q6NV74 2 98793846-98936259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.8;epididymis: 31.6" "Cell type enriched" "Detected in some" 9 "Adipocytes: 35.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 12.8;basal ganglia: 20.0;cerebral cortex: 30.8;hippocampal formation: 29.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 41.0;HDLM-2: 61.7;Karpas-707: 17.4;MCF7: 16.3;SiHa: 17.3;SK-BR-3: 22.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "amygdala: 19.1;basal ganglia: 45.5;cerebral cortex: 36.9;hippocampal formation: 54.9;olfactory bulb: 15.9" "HPA051082, HPA061678" Enhanced Approved "Microtubules,Cytokinetic bridge,Centrosome" Yes No "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Microtubules, Centrosome" "Cytokinetic bridge" "HPA051082: AB_2681337, HPA061678: AB_2684584" "unprognostic (3.56e-3)" "unprognostic (1.23e-3)" "unprognostic (5.88e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.24e-1)" "unprognostic (3.67e-3)" "unprognostic (2.12e-1)" "unprognostic (5.10e-2)" "unprognostic (7.65e-2)" "unprognostic (3.23e-2)" "unprognostic (3.61e-2)" "prognostic favorable (1.13e-5)" "unprognostic (1.22e-1)" "unprognostic (3.34e-1)" "prognostic favorable (1.33e-5)" "unprognostic (2.22e-2)" 5.0 0.9 12.8 1.5 20.0 0.5 5.1 0.0 30.8 5.1 0.0 5.9 8.0 2.1 31.6 11.2 22.6 2.9 3.4 29.7 0.0 4.1 0.3 6.0 0.8 0.0 0.0 0.6 4.7 7.7 6.6 4.5 0.0 2.3 4.6 0.1 11.0 4.6 1.7 6.4 7.5 2.3 0.0 1.3 8.3 6.2 0.0 1.0 5.0 1.5 1.8 2.2 5.5 3.6 8.4 0.4 0.2 3.2 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.4 4.9 0.0 10.4 0.0 0.2 7.4 0.3 0.4 0.0 61.7 1.2 0.0 0.5 0.5 0.0 0.0 0.1 0.3 2.3 0.1 1.2 0.1 2.5 0.0 0.0 17.4 0.0 16.3 0.2 1.3 0.1 8.3 0.9 0.0 0.0 0.8 3.2 6.5 5.8 0.9 17.3 22.5 0.1 0.0 8.7 1.4 10.7 0.0 1.3 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 20.0 0.0 30.8 29.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 CRAMP1 "CRAMP1L, KIAA1426" ENSG00000007545 "Cramped chromatin regulator homolog 1" Q96RY5 16 1612337-1677908 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041752 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA041752: AB_10796459" "unprognostic (3.67e-1)" "unprognostic (9.97e-2)" "unprognostic (2.72e-1)" "unprognostic (2.23e-1)" "unprognostic (3.41e-2)" "unprognostic (2.25e-3)" "unprognostic (5.78e-4)" "unprognostic (4.17e-2)" "unprognostic (8.53e-3)" "unprognostic (6.01e-2)" "unprognostic (1.55e-2)" "unprognostic (9.93e-2)" "unprognostic (3.86e-3)" "prognostic favorable (4.93e-4)" "unprognostic (8.57e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-2)" 8.0 7.5 7.4 5.6 6.2 13.5 9.0 15.0 6.9 11.1 5.9 10.9 8.1 10.3 6.2 9.0 10.7 5.4 8.3 6.6 4.6 9.4 6.3 9.9 7.6 5.4 5.2 12.5 8.8 5.7 12.4 6.9 5.3 12.0 5.4 9.9 8.4 6.4 7.9 11.0 9.5 6.7 3.2 11.0 9.0 22.9 5.5 10.7 12.7 4.8 6.0 9.6 9.5 7.1 8.5 15.5 15.6 14.5 9.8 9.7 20.3 14.4 7.5 11.5 8.2 11.2 14.0 12.0 12.3 9.9 7.1 15.3 18.7 10.0 10.3 12.7 22.6 14.2 16.0 6.9 7.1 19.0 20.6 8.5 12.6 14.5 12.1 11.2 12.4 17.9 19.6 7.1 6.3 12.4 14.8 10.6 14.9 4.9 8.7 51.2 8.4 16.1 8.2 7.5 16.6 14.0 15.8 11.3 8.3 10.9 9.9 24.3 15.2 11.9 12.8 11.4 13.9 15.0 23.3 24.3 3.7 13.0 10.8 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.3 0.0 0.1 7.4 6.2 15.0 6.9 6.6 4.6 5.4 5.2 5.3 3.2 5.5 7.1 10.4 16.0 17.0 0.0 2.7 0.0 5.2 0.0 12.0 8.6 9.3 8.0 0.0 4.3 8.6 9.2 18.8 4.7 12.8 6.1 1.9 5.5 28.0 11.1 14.5 6.8 2.4 4.6 0.0 2.0 3.0 5.4 5.1 15.3 5.1 11.0 6.8 4.3 5.6 3.3 0.0 6.6 0.0 8.2 0.0 9.6 4.4 4.3 0.0 0.0 6.6 6.2 4.1 0.0 0.0 7.1 4.7 6.8 4.7 9.9 6.0 1.6 2.9 17.9 6.6 7.1 5.2 17.3 18.4 9.4 0.0 5.3 5.2 5.6 5.5 5.9 CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 49.9;Breast myoepithelial cells: 40.1;Intestinal goblet cells: 56.9;Prostatic glandular cells: 49.3" "Group enriched" "Detected in all" 5 "breast cancer: 47.8;endometrial cancer: 28.7;prostate cancer: 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 81.8;OE19: 82.7;SK-BR-3: 174.6;T-47d: 139.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: AB_10669516" "unprognostic (1.35e-1)" "unprognostic (4.71e-2)" "unprognostic (8.13e-3)" "prognostic favorable (7.21e-4)" "unprognostic (2.04e-1)" "unprognostic (1.40e-2)" "unprognostic (5.51e-3)" "unprognostic (5.02e-2)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.12e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (9.34e-3)" 6.3 8.5 3.5 4.5 3.8 7.6 48.2 4.6 4.7 30.5 4.4 11.5 11.4 12.9 13.0 8.2 19.2 6.7 5.0 3.3 3.5 10.5 14.0 5.8 5.9 3.9 4.1 17.4 13.2 6.7 6.1 6.3 3.7 106.2 15.2 4.9 43.9 7.6 5.6 10.2 9.0 5.7 3.9 7.5 29.3 5.3 3.6 12.0 11.3 5.3 7.4 6.8 6.9 4.7 7.5 10.6 9.8 10.9 6.9 10.0 24.7 6.2 7.2 8.3 7.3 5.1 31.0 13.9 31.7 2.6 6.1 12.0 14.5 9.7 4.5 11.4 5.9 10.3 11.7 8.9 5.6 4.9 8.5 10.9 9.2 7.9 17.9 7.5 7.4 16.5 8.1 16.9 3.8 81.8 9.3 3.8 6.7 82.7 12.7 20.9 10.3 26.1 9.0 5.3 18.5 20.1 6.6 174.6 16.8 12.8 139.9 14.9 4.5 2.5 7.3 5.2 4.9 31.4 17.3 10.6 5.3 8.5 8.2 1.5 2.9 2.2 3.4 1.2 4.5 4.5 1.9 2.4 5.0 4.8 1.8 3.5 0.1 9.4 1.7 5.7 1.8 2.5 3.5 3.8 4.6 4.7 3.3 3.5 3.9 4.1 3.7 3.9 3.6 4.7 7.2 6.4 13.1 3.6 6.2 2.9 13.1 10.1 6.8 5.3 49.9 40.1 2.0 7.2 20.3 1.8 2.1 12.9 5.6 3.6 9.8 14.0 0.4 10.6 5.2 6.9 9.0 8.6 0.4 13.3 17.0 4.8 10.7 13.5 5.7 8.7 4.2 14.2 5.4 0.0 0.4 56.9 6.1 7.5 2.0 0.6 7.2 5.1 5.4 0.0 2.8 6.6 8.2 1.5 2.2 7.9 4.3 2.2 5.3 49.3 4.0 4.1 16.6 8.8 19.7 3.1 5.0 7.4 10.6 6.3 3.0 4.2 4.5 7.6 10.9 7.0 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CREBL2 ENSG00000111269 "CAMP responsive element binding protein like 2" O60519 12 12611827-12645108 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 130.6" "Cell type enhanced" "Detected in all" "Kupffer cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043738 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Nucleoplasm, Cytosol" "HPA043738: AB_10795041" "unprognostic (2.87e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" "unprognostic (7.51e-2)" "unprognostic (7.38e-2)" "unprognostic (4.51e-1)" "unprognostic (1.44e-1)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (5.82e-3)" "unprognostic (6.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (6.31e-2)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" 39.8 130.6 24.7 30.4 26.3 5.3 31.9 22.8 29.2 26.4 29.5 23.4 23.1 19.0 28.8 17.1 24.6 28.2 22.5 26.2 28.8 49.7 50.1 32.5 37.5 24.6 24.5 37.2 24.7 56.3 32.2 24.2 24.6 28.2 23.8 35.2 26.4 23.0 10.1 24.6 23.6 18.9 24.8 37.5 25.1 20.9 29.1 24.7 44.3 15.6 29.8 28.0 15.1 27.7 12.5 15.9 13.6 15.5 46.9 47.0 26.3 24.0 40.4 17.3 23.7 11.5 17.9 10.8 9.1 29.3 26.2 10.3 20.7 18.4 29.1 61.0 12.6 8.5 15.1 14.2 30.7 12.2 15.2 30.8 32.2 20.3 33.1 58.7 25.7 8.5 8.7 16.5 29.4 20.1 6.4 9.9 40.8 11.9 14.4 8.7 23.6 6.9 33.1 35.7 16.0 18.2 24.4 11.7 43.3 58.5 6.5 13.6 20.8 23.7 15.1 23.7 23.9 13.9 19.7 2.7 28.1 10.3 24.9 1.1 2.5 2.6 1.7 5.6 3.1 0.9 3.4 2.7 2.8 1.1 3.3 2.7 0.4 1.1 2.6 1.4 5.6 1.5 24.7 26.3 22.8 29.2 26.2 28.8 24.6 24.5 24.6 24.8 29.1 27.7 18.0 25.6 26.5 23.5 14.8 22.2 18.6 11.1 18.8 17.5 23.5 15.9 14.6 30.0 12.2 33.1 2.1 18.1 15.7 17.7 41.1 21.6 40.4 14.2 10.4 19.1 30.0 27.8 15.9 21.8 19.3 25.3 17.9 10.6 10.2 12.1 23.2 48.4 39.3 37.0 17.7 16.4 26.4 120.0 83.0 12.1 36.1 58.2 33.8 33.7 45.6 38.0 10.3 28.6 18.6 21.8 15.0 35.3 17.3 29.5 29.3 58.8 19.9 11.8 39.5 13.7 12.4 45.8 20.8 18.0 29.1 27.5 23.3 11.5 17.6 28.1 CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 980.8;Endometrial ciliated cells: 1761.1;Proximal enterocytes: 2548.8;Respiratory ciliated cells: 1702.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 699.8;CAPAN-2: 415.5;HaCaT: 464.1;HDLM-2: 329.5;OE19: 1305.8;T-47d: 586.0" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" 265.2 21.7 19.2 61.1 19.7 29.4 180.8 20.0 36.4 147.4 20.3 133.9 121.7 108.0 206.6 118.7 118.2 28.1 262.6 18.5 20.3 109.7 17.8 254.6 83.9 26.9 29.1 49.8 18.3 21.2 41.5 28.3 24.6 49.6 55.4 0.2 135.7 87.9 44.7 301.1 312.5 42.4 24.7 94.5 94.2 14.3 21.0 79.6 182.1 50.2 135.7 113.7 98.9 20.3 0.0 699.8 4.8 0.6 12.1 8.3 66.8 1.3 0.4 9.0 0.1 21.0 415.5 228.0 2.4 191.0 2.6 464.1 0.1 0.0 0.0 329.5 0.0 17.7 294.7 116.3 1.8 0.1 0.2 3.8 0.0 23.1 0.0 0.9 0.5 64.6 0.5 0.9 0.0 3.7 8.1 1.6 7.4 1305.8 36.4 181.3 0.0 45.5 0.0 0.0 18.5 1.3 2.6 1.2 0.0 0.5 586.0 106.4 1.5 0.4 0.4 5.5 0.0 0.3 0.2 17.9 0.0 0.0 0.6 121.8 218.6 313.1 209.2 214.4 135.1 697.0 442.0 222.1 442.9 384.2 85.4 100.2 13.9 323.5 283.9 291.3 694.8 465.6 19.2 19.7 20.0 36.4 18.5 20.3 26.9 29.1 24.6 24.7 21.0 20.3 50.2 980.8 256.2 0.3 350.7 186.5 1.2 79.5 67.2 0.0 88.1 18.3 1.0 2.8 501.3 51.5 0.0 2.1 287.8 360.4 1.9 20.5 3.6 1761.1 124.5 86.4 76.5 27.3 0.0 3.1 4.3 313.3 210.0 491.9 521.5 0.1 24.7 1.3 52.2 0.0 0.0 243.1 30.5 168.0 577.3 26.2 25.1 523.7 370.0 1.9 461.4 0.2 83.4 0.0 0.1 34.2 659.2 9.4 584.3 0.7 2548.8 2.5 1702.1 0.0 223.5 8.2 448.0 1.0 11.4 29.4 251.6 1.5 524.7 0.1 190.7 3.0 CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 1113.7" "Cell type enhanced" "Detected in many" "Adipocytes: 459.4;Cardiomyocytes: 863.3;Endothelial cells: 510.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.1;memory CD4 T-cell: 80.4;naive B-cell: 109.9;T-reg: 115.6" "Group enriched" "Detected in all" 30 "B-cells: 109.9;T-cells: 115.6" "Cell line enhanced" "Detected in many" "EFO-21: 321.9;MCF7: 306.5;SK-BR-3: 303.7;T-47d: 266.4;TIME: 259.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 160000 "Cluster 26: Non-specific - Mitochondria" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: AB_10797017" "unprognostic (2.68e-1)" "unprognostic (6.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.20e-3)" "unprognostic (9.68e-2)" "unprognostic (6.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-3)" 177.6 44.7 160.4 31.3 172.0 1.5 162.5 137.7 259.5 101.6 124.2 101.9 27.0 138.1 36.4 127.3 130.0 47.9 1113.7 172.7 186.4 205.1 52.7 185.7 30.0 157.3 158.7 51.2 46.1 19.2 175.0 49.6 158.6 89.0 8.3 4.1 100.0 72.9 52.5 128.9 82.8 32.0 145.0 104.1 66.1 92.8 191.9 10.4 155.6 42.7 16.5 121.4 100.4 140.8 2.5 201.2 37.9 98.3 4.3 19.9 10.0 17.5 1.9 2.8 1.0 7.1 44.2 0.2 321.9 73.8 4.5 166.8 3.6 50.8 0.1 2.3 1.9 0.2 132.5 73.8 24.3 0.0 25.5 10.5 4.4 5.2 26.2 38.4 192.7 0.2 0.5 1.4 26.8 306.5 0.5 0.6 10.0 45.7 143.4 0.4 7.7 9.9 140.1 0.6 61.6 175.3 30.0 303.7 1.9 4.9 266.4 0.1 259.3 82.7 38.8 2.3 50.5 0.7 0.6 0.9 24.3 0.3 179.3 0.2 1.9 0.0 7.5 0.9 6.8 52.1 80.4 17.2 3.6 109.9 17.8 4.5 1.0 3.7 0.5 0.5 115.6 10.4 160.4 172.0 137.7 259.5 172.7 186.4 157.3 158.7 158.6 145.0 191.9 140.8 459.4 157.0 33.7 17.9 15.0 153.2 96.7 206.4 29.0 2.7 110.0 140.7 863.3 107.2 127.1 189.4 4.2 2.6 8.2 0.9 154.6 106.8 37.9 125.1 28.8 510.4 25.2 9.7 16.4 87.6 30.5 132.9 32.1 126.6 7.6 0.4 346.3 30.4 3.0 94.2 3.0 0.3 81.4 11.8 92.6 84.0 28.0 9.3 156.5 27.2 2.5 57.2 1.0 4.5 3.1 48.9 0.1 14.7 7.0 37.4 0.2 17.0 155.7 4.0 276.1 108.1 339.5 27.8 46.1 20.1 196.8 32.0 32.5 5.9 0.2 103.2 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 203 "amygdala: 14.2;basal ganglia: 11.4;cerebellum: 27.1;cerebral cortex: 24.3;hippocampal formation: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255, HPA063619: " "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favorable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favorable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" 8.8 11.3 14.2 5.2 11.4 2.1 8.2 27.1 24.3 11.3 0.0 8.9 4.0 9.3 3.4 5.2 10.3 3.2 10.5 24.5 0.0 12.8 10.4 7.9 4.1 0.0 0.0 9.4 9.8 4.7 23.7 3.9 0.0 11.6 1.5 4.4 7.3 5.1 14.4 7.4 8.5 2.5 0.0 9.6 9.9 11.3 0.0 3.6 14.4 3.6 2.2 9.7 7.4 0.0 5.2 7.9 6.7 10.7 6.3 4.5 18.6 5.4 3.6 5.3 4.8 5.1 6.6 7.1 11.6 5.2 3.9 5.5 2.1 3.5 1.3 3.1 15.1 6.0 7.8 9.3 5.5 8.3 16.3 7.8 2.9 4.4 1.3 6.8 3.1 7.2 4.8 6.3 3.0 15.2 5.7 10.0 8.8 2.7 13.1 8.7 2.9 8.1 3.2 8.0 12.1 10.7 6.0 5.8 7.0 2.2 6.6 5.2 5.4 6.0 9.1 10.8 6.4 4.4 3.6 4.6 6.9 8.6 4.6 0.3 0.6 0.4 0.4 0.2 0.3 0.5 0.5 0.6 0.7 0.7 0.5 0.3 0.2 0.3 0.4 0.8 0.4 0.4 14.2 11.4 27.1 24.3 24.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 5.3 31.0 6.9 2.7 8.9 7.8 5.7 29.1 5.8 6.1 17.7 10.0 3.5 18.4 27.1 9.7 7.9 6.8 11.7 4.6 1.1 9.6 14.0 5.6 19.2 3.6 37.4 6.0 2.7 7.5 8.6 9.8 2.5 14.7 3.9 4.7 8.8 43.7 26.7 7.1 12.2 6.0 4.0 3.2 9.3 6.3 3.6 10.3 5.5 9.1 8.2 12.1 20.2 3.5 9.6 4.9 2.0 3.0 6.1 5.0 4.8 14.7 0.0 14.2 6.6 2.9 8.8 2.4 2.0 10.4 5.1 8.3 5.2 3.6 CRY1 PHLL1 ENSG00000008405 "Cryptochrome circadian regulator 1" Q16526 12 106991364-107093549 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018762 Approved Supported "Nucleoplasm,Nuclear membrane,Microtubules" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear membrane, Microtubules" "CAB018762: AB_2083970" "unprognostic (1.21e-3)" "unprognostic (4.74e-2)" "unprognostic (6.50e-2)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.84e-1)" "unprognostic (3.48e-2)" "unprognostic (3.61e-1)" "unprognostic (4.29e-3)" "unprognostic (1.34e-2)" "unprognostic (6.85e-3)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.82e-2)" "unprognostic (5.08e-1)" "unprognostic (1.85e-1)" "unprognostic (2.25e-1)" 13.3 12.4 8.5 7.6 9.8 12.4 11.2 16.2 10.9 11.1 16.7 12.6 11.5 14.2 6.4 11.0 16.4 16.7 11.7 8.4 9.0 13.7 13.6 19.3 5.8 9.8 10.1 9.0 13.5 8.8 8.4 12.1 9.9 11.3 8.6 21.3 9.0 11.5 10.9 9.0 12.7 16.8 9.7 8.7 16.2 37.3 9.9 19.0 17.0 11.0 6.7 15.6 8.6 12.5 17.3 16.9 20.6 23.0 14.6 9.1 36.9 17.9 19.1 36.0 24.2 19.9 10.1 0.0 11.1 16.7 22.7 11.6 26.8 9.3 39.6 17.3 16.6 16.9 15.3 13.8 18.6 17.3 14.2 8.6 9.6 26.4 24.9 17.8 30.5 31.4 19.3 14.6 22.7 12.1 39.2 19.7 25.1 16.5 24.6 34.5 52.3 6.1 25.3 20.2 37.1 19.2 33.6 22.1 10.9 20.0 15.6 9.6 13.5 20.9 22.2 14.6 16.2 26.6 26.6 7.8 10.2 16.3 17.5 12.0 3.2 5.8 12.8 4.7 16.1 1.9 9.6 8.2 4.3 1.9 8.9 8.8 1.4 6.4 8.9 2.8 13.5 5.7 8.5 9.8 16.2 10.9 8.4 9.0 9.8 10.1 9.9 9.7 9.9 12.5 16.3 16.0 16.2 20.5 9.7 69.2 47.9 4.3 55.2 16.8 30.4 14.7 11.1 11.5 6.1 11.0 20.9 8.3 29.1 12.7 17.6 11.4 12.8 27.3 19.3 20.1 19.6 11.2 22.4 16.3 13.4 24.5 45.9 33.2 5.1 6.2 12.1 20.2 6.3 26.9 38.4 9.7 6.1 7.3 21.0 4.8 11.5 8.8 16.0 13.1 16.3 22.8 19.6 35.2 32.8 21.5 7.0 17.3 15.3 29.7 7.7 16.1 18.7 13.7 6.6 24.3 19.2 108.0 32.4 24.3 59.5 15.1 29.7 5.7 6.8 27.0 CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2.6;Distal tubular cells: 1.9;granulocytes: 4.5;Muller glia cells: 4.3;Proximal tubular cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.4;HEK 293: 1.4;HeLa: 1.8;hTERT-HME1: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: AB_2682939" "unprognostic (1.36e-2)" "unprognostic (6.27e-4)" "unprognostic (6.30e-3)" "unprognostic (5.34e-2)" "unprognostic (8.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.15e-2)" "unprognostic (8.28e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-3)" 0.2 0.5 0.9 0.1 0.6 0.0 0.7 0.0 1.0 0.5 0.0 0.6 0.3 0.3 0.2 0.6 0.4 0.4 0.5 0.9 0.0 2.0 2.0 0.3 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.0 0.8 0.4 0.7 1.0 0.4 0.7 0.9 0.7 0.1 0.0 0.1 0.5 0.2 0.5 0.2 1.3 0.1 0.3 0.1 0.4 0.0 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.2 1.4 0.8 0.6 0.0 0.0 1.4 0.0 1.8 1.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.2 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.5 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 1.0 0.9 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.6 0.3 0.4 1.5 0.1 0.0 0.0 0.0 0.0 2.6 1.9 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 4.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.3 10.5 0.4 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.3 0.0 0.1 0.0 0.3 0.1 CRYBG1 "AIM1, ST4" ENSG00000112297 "Crystallin beta-gamma domain containing 1" 6 106360717-106572017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 61.9;placenta: 72.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 219.4;dendritic cells: 153.6;Plasma cells: 89.9;Syncytiotrophoblasts: 600.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 93.7;HBEC3-KT: 124.1;hTERT-HME1: 95.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.2" "Low region specificity" "Detected in many" "CAB026378, HPA030948, HPA030949" Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Microtubules, Cytosol" "CAB026378: , HPA030948: AB_2673670, HPA030949: AB_2673671" "unprognostic (1.66e-1)" "unprognostic (3.44e-2)" "unprognostic (9.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (3.69e-3)" "unprognostic (5.61e-2)" "unprognostic (8.97e-2)" "unprognostic (3.53e-2)" "unprognostic (8.89e-2)" "unprognostic (8.60e-2)" "unprognostic (3.25e-2)" 17.0 1.2 0.6 21.9 0.5 24.1 17.3 0.7 0.8 6.8 40.3 25.0 25.4 2.4 6.2 61.9 6.7 8.1 1.0 1.9 0.4 15.3 11.8 9.8 20.4 0.8 0.7 2.3 4.9 5.8 0.4 72.0 0.6 25.2 19.2 0.8 9.3 5.4 1.1 42.1 23.7 4.8 0.5 12.6 10.3 5.1 1.5 9.7 2.6 1.2 33.5 19.0 14.0 0.4 34.7 0.2 0.0 0.1 25.5 93.7 9.9 4.9 33.5 10.8 10.0 2.4 11.5 54.0 2.3 21.7 14.6 54.5 0.2 124.1 5.3 74.0 2.3 0.0 1.5 16.9 12.1 33.4 0.2 44.9 66.7 19.7 95.8 0.1 46.5 41.9 1.7 7.3 28.5 3.5 9.7 10.7 0.4 0.2 21.2 16.4 0.4 0.4 14.9 80.0 2.2 0.2 20.3 31.9 0.3 3.0 16.4 24.3 13.5 11.6 1.5 0.2 34.4 5.7 4.7 57.7 56.0 39.3 26.3 0.3 3.4 0.4 7.4 3.6 10.1 6.6 9.8 8.5 8.6 2.9 5.8 5.7 2.4 4.8 4.1 1.0 9.9 4.0 0.6 0.5 0.7 0.8 1.9 0.4 0.8 0.7 0.6 0.5 1.5 0.4 13.4 12.8 11.9 0.0 24.2 0.0 0.0 0.0 0.0 0.0 31.2 14.1 0.0 0.0 13.0 33.1 0.0 219.4 153.6 0.0 3.9 10.9 0.0 20.2 2.7 4.4 0.0 0.0 0.0 12.5 15.3 2.5 0.0 31.6 1.3 0.1 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.0 5.7 0.0 0.0 0.0 0.0 26.4 0.0 0.0 89.9 0.0 0.0 15.0 8.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 600.1 76.7 0.1 0.0 0.0 CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 329.8;liver: 254.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 485.2;Hepatocytes: 306.1;Proximal enterocytes: 509.9;Proximal tubular cells: 1033.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040403, HPA058848" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA 690000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: AB_10795632, HPA058848: " "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-2)" "prognostic favorable (1.76e-5)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-3)" "unprognostic (4.75e-3)" "unprognostic (1.19e-1)" "unprognostic (4.09e-2)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "prognostic favorable (2.30e-9)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (3.11e-1)" 33.7 31.8 69.5 15.4 81.3 11.2 27.1 75.4 78.1 33.0 65.6 62.1 190.2 30.5 51.7 24.7 26.5 30.0 30.4 65.2 79.0 329.8 254.1 19.9 19.4 76.3 71.9 19.8 46.9 31.4 38.1 16.1 76.1 32.2 49.3 20.7 41.6 36.5 17.0 16.3 131.6 22.8 77.2 23.3 45.2 4.9 71.9 18.0 35.0 20.7 16.3 20.9 23.6 89.8 8.1 6.9 6.4 42.7 31.6 36.1 5.8 11.1 20.0 4.8 3.9 2.6 7.8 0.1 20.6 15.5 10.9 1.9 5.7 9.9 4.9 19.4 4.7 14.2 0.8 55.1 18.1 4.6 12.2 21.5 6.4 3.9 22.0 17.1 51.7 20.3 1.0 5.8 12.7 29.2 12.7 7.2 0.4 68.7 10.2 6.4 3.8 1.0 40.8 16.9 4.2 5.0 6.6 3.1 51.0 3.0 21.2 18.0 50.1 5.8 2.6 14.3 7.1 7.6 1.6 0.0 11.1 7.9 24.5 5.8 50.7 3.2 23.2 59.6 18.9 20.5 30.6 22.1 60.5 23.1 23.5 22.2 1.7 15.6 50.6 6.4 37.5 43.8 69.5 81.3 75.4 78.1 65.2 79.0 76.3 71.9 76.1 77.2 71.9 89.8 29.2 6.4 10.3 57.8 17.7 10.3 15.9 29.7 6.2 6.1 22.0 11.6 10.5 35.8 25.6 77.3 12.5 22.0 10.0 138.5 485.2 26.1 3.6 32.5 8.8 29.1 9.1 6.9 54.5 31.6 11.2 29.8 34.1 27.2 25.3 8.8 50.7 306.1 71.4 1.7 35.3 89.0 32.6 91.6 34.3 4.3 26.1 51.3 37.4 13.1 19.3 112.2 9.2 33.7 114.1 43.2 219.1 24.0 14.3 23.0 509.9 1033.9 20.9 12.6 19.7 23.4 14.7 1.0 2.7 13.0 9.2 20.8 20.1 20.7 105.2 15.0 CTAG2 "CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803" ENSG00000126890 "Cancer/testis antigen 2" O75638 X 154651972-154653579 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 5.4;testis: 10.4" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 77.3" "Cancer enhanced" "Detected in many" "melanoma: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 104.1;K-562: 140.6;OE19: 203.6;RPMI-8226: 311.3;SK-BR-3: 195.4;U-266/84: 356.9" "HPA071467, HPA076586" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA071467: AB_2686402, HPA076586: " "prognostic unfavorable (2.35e-4)" "unprognostic (3.87e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-2)" 0.3 0.8 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.8 1.5 0.0 5.4 0.0 0.0 3.4 0.7 0.3 0.0 0.1 0.0 0.5 2.0 0.0 0.3 2.6 0.1 0.3 0.0 0.0 0.1 0.0 3.3 0.4 0.2 0.0 0.0 0.4 0.5 10.4 0.0 3.0 0.1 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 104.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.6 2.9 0.0 0.0 0.2 0.0 0.0 203.6 0.0 0.0 0.0 311.3 0.0 0.0 0.4 0.0 0.0 195.4 0.3 0.0 0.2 0.6 0.3 6.3 0.2 0.7 0.2 2.6 356.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.2 0.0 2.1 0.0 0.0 1.2 0.9 0.0 3.9 0.0 0.2 0.0 1.8 0.2 0.0 0.0 0.5 0.0 11.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 3.1 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.7 1.2 0.5 0.0 0.0 0.6 18.5 77.3 0.0 0.0 1.1 0.1 0.0 0.0 0.0 CTCFL "BORIS, CT27, dJ579F20.2" ENSG00000124092 "CCCTC-binding factor like" Q8NI51 20 57495966-57525652 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 11.0" "Group enriched" "Detected in some" 15 "Spermatocytes: 61.3;Spermatogonia: 143.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 4.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HMC-1: 79.6;K-562: 116.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA001472 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA001472: AB_1078583" "unprognostic (2.50e-1)" "unprognostic (4.01e-2)" "unprognostic (7.70e-2)" "unprognostic (1.85e-5)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-2)" "unprognostic (5.26e-3)" "unprognostic (3.60e-1)" "unprognostic (2.20e-1)" "unprognostic (9.00e-2)" "unprognostic (4.16e-2)" "unprognostic (4.75e-4)" "unprognostic (2.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.84e-2)" 0.1 0.2 0.4 0.2 0.5 1.0 0.2 1.2 0.6 0.0 0.1 0.1 0.2 0.3 0.4 0.2 0.1 0.2 0.2 0.4 0.5 0.2 0.4 0.2 0.4 0.1 0.0 0.2 0.5 0.1 0.2 0.3 0.1 0.2 0.2 0.9 0.1 0.1 0.2 0.5 0.3 0.1 0.0 0.3 0.2 11.0 0.3 0.1 0.4 0.1 0.1 0.1 0.0 2.0 0.1 0.1 0.1 0.5 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.4 0.2 0.1 0.3 0.4 0.2 0.1 0.0 0.4 0.2 0.3 0.7 0.1 0.2 0.2 79.6 0.0 0.0 0.1 0.0 0.1 0.0 0.2 116.1 0.6 0.0 0.1 0.3 0.4 0.3 0.1 0.1 0.3 0.2 0.2 0.1 0.3 0.3 0.3 0.1 0.2 0.3 0.4 0.2 0.1 0.5 0.3 0.2 0.3 0.1 0.3 0.1 2.9 0.3 0.3 0.4 0.5 0.1 0.3 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.4 0.1 0.1 0.9 0.2 0.2 0.2 0.1 0.0 0.4 0.5 1.2 0.6 0.4 0.5 0.1 0.0 0.1 0.0 0.3 2.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 3.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.2 0.2 0.0 0.0 6.6 0.1 0.2 61.3 143.8 0.0 0.0 0.0 0.1 0.0 0.1 0.2 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 372.9;granulocytes: 263.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 308.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Enhanced Nucleoplasm,Centrosome,Cytosol No No "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Centrosome, Cytosol" "HPA004742: AB_1847323, HPA027906: , HPA027907: AB_10601362" "unprognostic (2.81e-1)" "unprognostic (3.42e-1)" "unprognostic (8.80e-2)" "unprognostic (1.88e-3)" "unprognostic (1.93e-1)" "unprognostic (2.55e-2)" "unprognostic (1.44e-1)" "unprognostic (5.11e-2)" "unprognostic (1.02e-1)" "unprognostic (3.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (5.31e-2)" 26.9 16.8 20.9 27.3 22.8 41.8 23.8 21.6 24.8 23.7 23.4 31.8 21.7 27.7 31.1 23.4 25.3 19.8 32.3 22.0 22.4 22.9 46.8 25.3 39.3 22.8 22.3 27.1 17.3 19.7 18.2 22.1 21.7 23.4 23.1 18.8 18.5 30.6 33.3 25.3 25.1 30.6 21.6 54.0 34.8 43.3 22.1 40.1 17.1 20.9 41.2 25.8 20.4 23.6 66.7 60.3 56.7 44.6 40.3 32.8 89.2 41.9 43.7 98.0 86.0 224.8 52.4 73.9 59.6 42.7 94.4 69.8 77.1 98.6 105.3 36.1 38.0 243.0 33.2 110.2 41.8 77.4 308.0 35.1 58.9 55.6 54.8 34.1 59.8 103.8 66.8 29.6 53.5 54.9 127.0 101.4 51.4 74.9 85.8 87.9 109.1 56.3 42.9 55.0 45.1 53.6 72.5 102.3 75.4 52.3 50.6 61.1 44.5 97.4 58.0 64.9 68.8 34.1 46.6 85.5 68.5 48.6 52.7 267.9 77.7 103.3 51.0 103.0 49.1 88.9 49.9 53.8 110.3 83.4 49.8 53.6 16.9 79.9 109.6 86.9 66.2 71.3 20.9 22.8 21.6 24.8 22.0 22.4 22.8 22.3 21.7 21.6 22.1 23.6 28.6 28.9 26.4 21.2 40.0 22.8 32.9 40.7 13.1 26.1 13.0 13.2 39.8 17.2 34.1 18.4 18.8 147.8 40.4 21.1 37.2 34.8 372.9 24.2 24.9 32.5 20.9 43.7 31.6 34.7 69.4 28.7 48.4 21.6 263.6 34.4 44.3 45.2 49.3 18.5 35.6 27.3 42.7 36.0 35.5 131.2 34.2 44.5 26.6 14.0 89.8 32.1 40.2 30.7 39.8 31.9 21.5 33.4 21.6 22.3 34.7 43.1 26.1 25.8 19.7 25.4 48.0 79.4 45.2 10.7 22.4 52.9 38.8 23.7 24.2 20.6 CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 93.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2382.9;Excitatory neurons: 1253.9;Inhibitory neurons: 1124.0;Oligodendrocyte precursor cells: 1418.0;Oligodendrocytes: 433.8" "Cancer enriched" "Detected in many" 16 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.1;MCF7: 9.0;SK-BR-3: 5.3;U-266/84: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: AB_2669150, HPA071124: " "unprognostic (7.32e-2)" "unprognostic (1.51e-3)" "unprognostic (2.23e-1)" "unprognostic (5.16e-2)" "unprognostic (5.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (9.13e-2)" "unprognostic (9.86e-2)" "unprognostic (8.95e-3)" "unprognostic (2.66e-1)" "unprognostic (9.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" 0.2 0.7 79.2 0.2 79.3 0.0 0.9 49.7 75.7 0.1 15.2 1.1 0.1 0.1 0.3 0.1 0.2 2.6 3.8 84.6 56.7 0.0 0.5 0.7 0.1 93.8 72.6 0.5 15.8 0.0 9.0 0.3 71.5 0.9 0.3 7.0 0.8 0.2 0.1 0.7 0.5 0.1 77.7 3.9 0.6 2.6 83.7 0.2 0.2 0.1 0.0 0.1 0.2 76.1 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 9.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.0 17.5 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.2 79.3 49.7 75.7 84.6 56.7 93.8 72.6 71.5 77.7 83.7 76.1 0.1 0.0 0.0 2382.9 0.1 0.0 0.1 0.0 0.0 24.0 7.9 4.1 12.7 28.6 0.0 1.8 0.0 0.0 0.0 0.1 3.9 6.5 25.6 0.8 0.1 0.8 4.9 0.0 1253.9 6.1 0.2 0.5 0.0 0.9 0.0 0.0 0.0 0.2 0.1 8.4 1124.0 0.1 0.0 0.0 0.7 31.1 1.5 0.2 0.0 69.3 0.0 33.0 0.0 1418.0 433.8 2.2 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.6 0.0 3.3 0.3 4.6 5.9 0.0 0.0 0.0 0.1 0.5 0.3 0.1 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 320.9;Muller glia cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 23.1;SK-MEL-30: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 57.8 70.0 68.1 0.8 76.3 0.3 62.2 74.5 74.0 78.8 90.2 76.7 3.0 89.2 21.9 15.6 70.8 10.0 100.2 63.2 74.2 46.9 66.0 32.9 3.6 75.0 70.3 99.1 31.7 20.0 43.3 3.8 68.4 53.5 3.5 26.2 55.7 17.1 91.9 44.4 29.5 12.2 77.2 25.0 54.3 109.7 71.0 3.0 40.6 27.6 3.0 56.6 58.7 86.6 0.0 17.0 3.1 5.4 14.2 8.6 3.4 13.0 11.4 6.3 2.3 0.0 2.2 0.0 21.3 10.4 0.0 1.2 6.8 2.6 4.8 3.7 0.0 0.5 7.0 0.0 9.9 0.3 4.4 22.3 9.1 0.8 1.6 13.7 3.8 2.0 5.4 1.6 5.2 4.6 0.1 1.7 0.9 3.7 9.7 0.0 0.0 1.5 7.1 0.3 4.3 6.9 23.1 0.3 59.5 0.3 7.4 0.6 3.3 1.8 2.9 1.5 1.2 21.2 0.2 0.0 2.2 0.0 2.9 0.0 0.4 0.3 3.9 0.6 4.1 1.5 3.5 4.6 0.6 1.4 6.4 4.1 0.1 4.6 0.2 0.9 1.3 2.2 68.1 76.3 74.5 74.0 63.2 74.2 75.0 70.3 68.4 77.2 71.0 86.6 36.6 12.8 15.6 31.3 5.9 39.8 62.4 8.5 37.5 107.9 45.3 80.6 57.9 41.5 7.4 36.8 41.7 31.6 9.6 0.6 15.6 13.1 163.3 1.7 22.8 27.2 12.0 11.4 26.5 7.5 9.5 118.1 8.2 5.3 9.5 52.1 56.0 67.8 14.9 134.6 31.3 3.1 18.3 21.5 32.8 320.9 145.7 13.1 156.5 12.2 3.1 196.6 17.5 21.6 29.4 5.9 3.2 121.9 12.9 50.5 1.3 44.7 3.3 77.9 78.9 62.0 45.9 169.6 43.3 3.6 25.3 23.7 9.5 30.7 4.3 32.9 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Cytotrophoblasts: 122.3;Extravillous trophoblasts: 153.0;Granulosa cells: 54.2;Syncytiotrophoblasts: 67.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Group enriched" "Detected in many" 8 "BEWO: 592.6;SuSa: 739.0" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.2 0.2 0.6 0.3 0.7 0.3 5.8 0.8 1.6 43.1 0.8 2.9 1.1 2.8 1.7 19.8 1.3 0.5 0.1 0.6 0.5 21.3 0.2 0.9 0.1 0.7 0.6 0.2 2.1 1.4 1.5 16.8 0.6 0.7 3.2 17.2 9.4 0.1 0.7 52.5 0.4 0.8 0.5 0.2 2.8 65.8 0.6 643.6 1.3 0.1 6.0 0.4 20.1 1.0 37.1 5.2 12.1 33.1 0.6 0.0 592.6 0.5 0.0 7.1 4.7 81.0 37.7 0.3 2.8 0.5 50.5 67.2 58.8 43.9 9.7 0.1 4.4 0.8 1.9 3.1 0.2 0.1 3.3 0.0 9.2 1.5 0.8 0.9 2.4 8.5 0.5 0.2 14.4 15.2 0.9 0.3 76.2 78.9 10.7 0.0 27.3 0.1 11.4 3.7 2.4 3.6 39.1 13.1 13.2 739.0 21.1 3.2 0.0 1.0 23.6 0.2 3.5 5.7 20.6 0.8 1.6 0.4 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.2 3.3 0.0 15.1 0.0 0.1 0.6 0.7 0.8 1.6 0.6 0.5 0.7 0.6 0.6 0.5 0.6 1.0 0.9 0.0 1.1 0.3 0.9 30.3 13.0 63.7 19.9 4.6 13.1 9.9 1.3 0.0 17.4 1.8 10.4 122.3 6.9 4.7 1.9 1.8 2.6 15.0 2.9 1.8 1.8 0.0 0.6 0.8 153.0 3.2 0.0 24.0 0.0 54.2 0.4 0.0 13.6 0.0 0.9 1.5 10.2 0.8 3.0 8.2 4.1 2.4 0.0 0.0 0.2 6.5 0.0 0.0 3.5 0.5 10.5 1.2 0.0 8.1 0.1 22.1 4.2 36.6 6.6 1.4 3.6 46.7 33.7 8.2 11.9 67.3 0.5 0.7 4.2 8.4 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Cell line enhanced" "Detected in many" "A-431: 450.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 91.7 142.5 28.3 15.6 30.0 4.9 82.9 29.7 32.3 112.3 28.5 84.9 28.4 117.8 18.7 131.6 85.0 35.1 106.9 27.7 28.2 109.6 66.9 74.8 9.0 33.2 30.8 112.9 79.5 18.1 94.1 23.9 30.9 101.6 23.8 8.4 92.9 27.0 65.7 104.4 70.9 31.8 29.5 53.3 92.2 62.0 30.3 8.7 89.5 14.5 12.7 88.1 101.2 32.5 450.2 97.2 32.0 37.2 53.2 81.9 52.5 93.8 92.5 80.7 63.4 129.5 110.3 17.5 90.6 121.1 86.3 97.3 38.6 98.7 58.7 35.5 39.1 1.7 73.6 61.1 113.9 0.4 22.6 116.6 68.0 89.4 50.2 84.4 68.8 0.5 51.3 3.3 80.9 122.9 0.9 6.4 35.0 163.4 58.6 0.2 39.3 14.3 90.5 143.7 26.3 44.9 68.3 93.2 158.0 57.2 75.8 1.9 86.8 70.8 45.3 111.2 63.6 7.4 5.2 1.0 141.1 0.4 98.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 2.1 0.0 0.1 0.4 0.0 6.8 28.3 30.0 29.7 32.3 27.7 28.2 33.2 30.8 30.9 29.5 30.3 32.5 95.3 44.8 51.8 61.7 4.0 151.9 102.8 85.8 46.1 39.4 81.0 57.9 64.1 80.1 95.4 134.3 18.8 83.8 1.6 224.4 64.6 146.5 12.4 86.4 84.8 89.9 74.4 18.9 93.4 221.5 95.6 89.1 76.0 116.1 6.3 117.7 78.9 44.1 10.4 38.7 65.4 123.8 57.0 8.9 34.1 26.1 103.2 38.6 122.7 28.1 5.9 42.5 0.0 40.2 145.8 260.6 177.8 98.9 3.1 153.5 108.4 164.3 89.4 32.5 59.2 61.0 87.5 32.0 47.0 76.7 174.9 106.3 5.4 91.4 111.9 258.1 CTXN1 FLJ25968 ENSG00000178531 "Cortexin 1" P60606 19 7924491-7926135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 275.1;endometrium 1: 85.7" "Cell type enriched" "Detected in many" 4 "Endometrial ciliated cells: 127.7" "Group enriched" "Detected in all" 4 "endometrial cancer: 69.5;glioma: 56.3;ovarian cancer: 138.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 96.4;HEK 293: 67.5;NTERA-2: 72.4;REH: 57.3;SCLC-21H: 56.2;SH-SY5Y: 94.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016669 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA016669: AB_1847330" "unprognostic (1.49e-2)" "unprognostic (3.52e-2)" "unprognostic (1.79e-2)" "unprognostic (2.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (5.42e-2)" "unprognostic (2.17e-1)" "unprognostic (2.58e-1)" "unprognostic (2.28e-2)" "unprognostic (1.69e-3)" "unprognostic (3.31e-2)" "unprognostic (1.56e-3)" "unprognostic (4.84e-2)" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "unprognostic (9.41e-2)" 6.5 12.5 176.3 0.9 275.1 0.1 3.2 0.0 173.0 36.9 0.0 61.3 0.9 85.7 2.9 2.6 43.0 0.2 1.0 199.1 58.0 11.7 0.4 7.0 0.0 0.0 21.3 6.2 2.2 1.1 57.0 0.3 1.0 16.3 0.4 0.2 6.4 12.4 0.5 4.1 4.7 4.9 0.0 1.4 8.8 27.8 85.5 0.3 2.8 0.1 0.0 21.2 13.2 40.7 33.5 8.1 20.5 96.4 0.0 0.3 4.8 8.5 2.3 4.1 2.4 2.4 5.0 0.2 16.2 2.0 2.2 35.9 4.7 0.9 0.2 3.0 67.5 0.7 5.3 1.5 0.9 1.8 1.9 0.0 2.7 1.4 0.9 9.8 5.4 9.1 21.3 0.3 0.5 40.5 18.5 13.6 72.4 2.4 34.1 57.3 0.0 6.4 15.0 1.4 56.2 94.5 5.2 2.8 9.9 1.7 21.2 0.6 8.3 2.1 33.1 3.9 4.8 0.7 1.0 4.8 8.0 3.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.3 275.1 0.0 173.0 199.1 58.0 0.0 21.3 1.0 0.0 85.5 40.7 0.6 0.0 0.0 3.3 0.7 1.1 4.1 1.5 2.2 0.3 15.3 6.7 0.4 1.5 1.0 9.2 4.2 0.2 0.2 0.5 3.9 7.8 9.5 127.7 22.4 1.6 9.1 0.0 20.6 0.4 0.4 3.0 0.0 7.9 0.0 13.3 0.7 0.1 0.3 0.0 3.5 0.5 2.0 0.3 0.5 27.1 1.2 0.5 1.8 4.7 0.0 0.6 0.0 1.5 2.9 1.7 1.2 1.9 0.0 19.9 0.0 11.9 21.0 0.4 0.0 0.2 17.7 6.0 16.0 0.3 2.0 0.3 0.6 3.2 0.2 6.4 CUEDC1 ENSG00000180891 "CUE domain containing 1" Q9NWM3 17 57861243-57955412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Oligodendrocytes: 117.9;Rod photoreceptor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 21.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 21.7" "Cell line enhanced" "Detected in many" "T-47d: 116.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023050, HPA024836" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Centrosome "HPA023050: AB_1847332, HPA024836: AB_1847333" "unprognostic (4.46e-1)" "unprognostic (3.76e-3)" "unprognostic (4.77e-2)" "unprognostic (4.87e-3)" "unprognostic (4.04e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (2.65e-5)" "unprognostic (6.69e-2)" "unprognostic (1.53e-2)" "unprognostic (6.65e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "prognostic favorable (8.46e-4)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (2.52e-2)" "unprognostic (2.65e-2)" 20.5 19.2 19.1 13.9 29.5 8.6 17.2 23.2 22.8 31.5 20.6 40.9 7.6 24.7 7.9 32.4 32.4 19.7 38.8 16.6 22.5 25.1 6.1 21.2 7.5 29.5 27.5 9.5 19.0 11.3 21.6 11.9 24.0 24.4 10.6 30.4 30.9 26.3 86.6 11.7 13.2 25.6 21.9 10.6 23.2 3.2 27.8 5.5 18.2 39.7 5.5 31.3 21.2 33.8 27.1 81.7 83.7 15.1 13.5 24.4 2.8 18.8 37.6 38.5 27.7 15.1 100.9 0.4 74.3 36.2 32.6 21.2 9.3 40.1 13.7 52.8 15.8 0.9 58.4 12.6 32.1 0.3 6.3 25.2 23.7 22.5 18.9 33.8 18.8 0.5 1.1 0.4 35.8 15.2 1.4 0.6 2.9 30.7 22.5 2.8 21.6 4.0 25.8 17.5 34.5 18.9 7.9 8.4 32.0 14.2 116.8 2.9 24.2 101.9 63.4 28.2 42.4 0.0 0.4 0.4 44.3 3.7 83.3 0.7 0.5 2.5 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.2 1.9 21.7 0.0 0.2 19.1 29.5 23.2 22.8 16.6 22.5 29.5 27.5 24.0 21.9 27.8 33.8 14.1 19.2 5.9 22.5 0.9 4.1 15.6 6.5 13.1 47.1 11.5 11.6 16.1 17.2 10.4 22.0 64.6 0.7 30.9 6.2 7.9 20.3 0.4 24.6 6.3 10.7 3.5 0.0 4.8 26.3 0.4 15.8 10.2 22.9 0.0 10.0 3.9 3.4 17.3 10.1 13.0 4.5 18.3 11.3 7.3 2.9 6.8 12.9 5.4 30.9 4.3 31.8 0.0 31.2 117.9 27.7 2.1 5.3 0.1 21.8 0.7 8.6 17.6 64.8 6.6 26.6 15.3 0.0 1.3 19.0 2.4 0.7 0.7 1.6 4.2 17.3 CUTC CGI-32 ENSG00000119929 "CutC copper transporter" Q9NTM9 10 99702558-99756134 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 385.5;tongue: 204.2" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038619, HPA058231" Enhanced Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" Nucleoli "HPA038619: AB_10672649, HPA058231: " "unprognostic (1.25e-2)" "unprognostic (5.92e-2)" "unprognostic (2.70e-1)" "unprognostic (8.66e-2)" "unprognostic (7.39e-2)" "unprognostic (1.39e-1)" "unprognostic (3.55e-3)" "unprognostic (8.67e-2)" "unprognostic (5.36e-2)" "unprognostic (1.81e-1)" "unprognostic (5.87e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.81e-7)" "unprognostic (1.00e-1)" "unprognostic (3.42e-2)" "unprognostic (2.41e-1)" "unprognostic (3.97e-1)" 38.7 15.5 19.3 14.6 21.9 23.6 27.3 20.8 25.9 17.3 17.3 19.4 11.1 14.7 11.0 16.0 17.1 12.1 41.7 18.7 20.7 13.5 30.2 15.1 22.3 21.0 20.6 12.6 14.2 8.6 7.8 11.3 21.3 16.1 15.9 28.3 16.9 11.2 385.5 18.6 20.9 14.4 20.1 28.6 18.6 43.4 20.3 23.9 13.2 204.2 19.7 43.8 16.7 25.0 27.4 57.7 19.9 60.7 71.8 32.8 10.8 22.0 28.0 21.6 24.2 26.7 20.5 98.9 19.1 37.5 10.6 22.9 40.8 36.6 23.9 29.5 39.0 32.9 26.1 42.7 33.2 61.5 15.5 34.0 22.3 34.5 71.1 26.8 37.8 56.2 29.6 21.4 16.4 19.4 55.7 63.2 20.0 27.7 21.4 37.5 23.3 38.3 22.8 11.2 6.5 14.8 10.1 15.9 28.9 27.1 25.3 34.7 21.2 9.0 12.2 9.9 29.5 34.7 48.5 69.6 29.4 130.0 8.2 70.6 42.6 111.7 56.9 35.2 60.0 73.4 53.9 54.9 47.1 66.5 74.4 57.2 68.6 63.1 46.0 54.2 57.0 45.3 19.3 21.9 20.8 25.9 18.7 20.7 21.0 20.6 21.3 20.1 20.3 25.0 26.3 9.6 12.5 15.3 32.8 12.1 14.7 23.1 5.7 18.7 12.6 15.2 40.6 14.3 14.9 5.5 8.4 18.6 23.2 4.6 21.5 16.9 12.6 11.4 12.0 19.8 12.1 28.2 8.5 17.4 13.5 32.8 10.7 8.3 30.4 14.4 27.5 23.4 20.9 11.8 9.0 7.4 12.2 17.0 11.7 10.8 13.1 16.6 30.2 7.5 28.0 25.9 21.6 8.0 26.9 10.5 7.4 16.1 27.2 16.1 19.2 34.8 21.5 33.0 19.7 27.1 15.5 163.3 36.7 14.3 10.9 13.5 25.6 36.3 9.6 11.6 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CYB5B CYB5-M ENSG00000103018 "Cytochrome b5 type B" O43169 16 69424619-69466264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 318.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007893 Approved Approved "Endoplasmic reticulum,Centriolar satellite,Cytosol" NA NA 99000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "Centriolar satellite, Cytosol" "HPA007893: AB_1847369" "unprognostic (1.13e-1)" "unprognostic (4.47e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (2.87e-3)" "unprognostic (4.35e-3)" "unprognostic (3.87e-1)" "unprognostic (1.44e-2)" "unprognostic (1.52e-2)" "unprognostic (3.10e-1)" "prognostic favorable (6.38e-5)" "unprognostic (9.69e-3)" "unprognostic (4.66e-2)" "unprognostic (3.78e-2)" "unprognostic (1.30e-2)" 60.2 318.0 52.3 51.4 53.9 20.9 50.4 46.0 69.9 45.8 43.6 92.6 69.5 49.3 72.8 59.3 58.2 45.4 58.0 56.9 51.2 71.9 83.8 54.1 68.8 50.7 48.1 44.0 40.1 77.7 28.6 73.8 50.6 47.6 116.0 49.4 36.3 48.3 65.8 45.8 67.8 61.6 44.7 49.6 49.3 38.6 52.3 74.3 54.1 78.2 76.9 80.4 38.2 48.4 186.2 576.4 232.9 144.9 105.1 139.3 99.5 162.3 224.1 266.0 249.2 406.1 221.3 168.0 159.3 157.9 216.0 214.5 224.4 235.0 300.0 90.2 85.5 81.2 97.1 479.1 154.7 169.1 172.4 120.9 116.3 315.9 149.6 111.8 254.7 190.5 133.6 78.4 165.2 241.2 278.9 204.1 173.5 171.4 78.4 260.0 128.7 184.3 359.3 208.7 135.7 69.7 431.6 82.0 142.2 119.0 159.0 133.2 115.9 152.2 124.5 102.2 145.5 94.7 227.0 516.6 157.0 138.0 180.0 121.1 57.6 71.5 103.8 80.0 85.0 68.8 76.9 81.8 69.8 63.1 62.8 75.5 17.1 96.4 59.7 124.2 134.6 105.6 52.3 53.9 46.0 69.9 56.9 51.2 50.7 48.1 50.6 44.7 52.3 48.4 36.2 44.8 46.8 44.7 47.2 49.8 49.2 84.0 66.0 22.8 28.6 26.0 25.0 30.0 51.4 62.5 6.2 159.8 66.7 112.7 78.2 66.2 18.8 56.4 33.3 61.7 23.4 38.7 40.9 70.4 94.1 38.4 27.5 87.7 60.2 36.6 43.9 54.9 64.8 30.3 30.4 76.6 83.4 30.1 57.5 22.7 44.4 33.4 62.2 24.4 55.8 63.0 96.8 23.6 39.4 70.5 78.8 44.4 28.1 34.9 75.9 62.9 49.5 31.6 46.0 22.2 36.5 48.1 46.6 44.9 42.3 59.8 54.1 84.8 61.6 50.4 CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.2;kidney: 139.9" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Collecting duct cells: 158.2;Distal tubular cells: 174.1;Excitatory neurons: 117.7;Inhibitory neurons: 147.5;Oligodendrocyte precursor cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 202.4;JURKAT: 145.2;MOLT-4: 204.8;U-266/70: 153.6;U-698: 142.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: AB_2685955, HPA071459: AB_2686400" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-6)" "unprognostic (3.76e-1)" "unprognostic (4.58e-2)" "unprognostic (1.14e-1)" "unprognostic (6.91e-3)" "unprognostic (3.97e-2)" "unprognostic (5.25e-2)" "prognostic favorable (1.18e-4)" "unprognostic (3.81e-2)" "prognostic favorable (3.21e-12)" "unprognostic (2.90e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.49e-2)" 3.2 12.3 61.0 30.8 54.4 55.5 2.8 23.6 103.8 3.1 16.3 8.9 6.3 6.6 25.1 3.8 9.2 8.8 10.4 112.2 25.6 139.9 18.3 12.2 57.1 8.4 33.4 4.8 7.1 64.9 40.1 9.3 6.6 5.8 9.8 35.4 4.0 5.0 7.0 2.8 17.5 5.6 0.0 35.0 20.9 5.3 67.7 85.9 9.9 1.7 55.3 8.3 2.3 37.7 0.3 31.8 47.3 28.8 1.1 1.3 81.5 6.1 9.6 2.5 6.8 6.2 0.6 202.4 14.5 3.4 7.4 0.4 38.0 27.1 5.8 48.8 60.8 28.4 42.3 24.9 4.1 29.1 71.8 5.4 10.9 8.1 0.5 18.8 8.8 145.2 0.4 81.1 7.0 7.7 204.8 5.5 22.3 0.5 8.5 50.6 1.4 102.3 24.5 30.2 70.5 27.4 0.6 28.3 4.6 46.8 19.9 0.8 11.3 2.0 21.4 7.1 5.4 153.6 40.2 142.8 21.4 33.5 11.8 64.8 12.6 90.1 85.9 57.4 61.0 35.8 60.6 75.7 17.8 35.9 63.2 73.2 41.0 53.9 133.7 43.9 53.5 78.0 61.0 54.4 23.6 103.8 112.2 25.6 8.4 33.4 6.6 0.0 67.7 37.7 1.8 3.2 26.9 133.5 76.6 1.1 2.2 2.8 3.4 62.0 3.5 3.4 17.9 8.6 7.4 158.2 16.7 37.2 78.8 6.0 174.1 9.7 15.3 2.8 1.8 2.6 14.4 11.6 117.7 1.6 43.0 3.6 6.1 6.2 2.5 23.1 5.7 30.8 5.3 90.9 147.5 5.6 4.1 6.5 11.4 24.2 1.8 15.7 7.2 23.4 20.3 14.0 101.0 120.6 33.8 1.9 9.9 6.8 41.1 1.3 5.4 55.0 4.7 35.2 0.0 12.2 11.0 3.2 13.1 0.8 1.4 21.1 88.8 2.1 9.1 1.7 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 48.3;Basal respiratory cells: 142.7;Basal squamous epithelial cells: 74.0;Club cells: 47.0;Proximal tubular cells: 61.3;Urothelial cells: 36.7" "Cancer enhanced" "Detected in many" "lung cancer: 18.3;urothelial cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "A549: 411.5;Hep G2: 122.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022261, HPA063771" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA022261: AB_1847427, HPA063771: AB_2685120" "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" 0.0 0.0 0.2 0.4 0.4 0.0 3.7 0.0 0.3 1.7 0.0 0.0 0.1 14.9 0.2 3.8 0.2 0.0 0.0 0.1 1.8 35.3 0.4 0.7 0.2 0.4 2.0 0.0 0.0 0.0 0.2 10.0 0.3 2.9 0.0 0.0 0.3 2.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.2 1.3 0.0 10.5 28.7 1.3 0.2 0.5 411.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 12.6 0.0 3.2 0.0 0.9 15.8 0.0 0.1 0.1 0.0 0.0 0.0 6.5 122.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 7.0 1.3 0.0 2.6 0.6 0.0 0.1 0.1 0.0 0.0 0.0 16.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.1 1.8 0.4 2.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 1.3 22.8 48.3 142.7 74.0 0.0 11.0 8.6 0.4 0.0 47.0 0.0 0.0 0.1 0.1 0.1 5.9 0.1 0.0 0.7 0.5 0.3 0.0 0.0 0.2 0.0 0.1 2.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 9.8 0.0 61.3 13.1 0.0 0.0 0.0 0.6 0.0 0.0 3.3 19.6 0.1 0.1 0.0 0.2 36.7 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CYTH2 "ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like" ENSG00000105443 "Cytohesin 2" Q99418 19 48469208-48482314 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014872, HPA060662" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus, Plasma membrane" "CAB014872: , HPA060662: AB_2732652" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.66e-1)" "unprognostic (2.83e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (2.33e-2)" "unprognostic (9.19e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.21e-4)" 8.1 12.1 17.2 11.4 17.8 8.1 14.2 20.3 19.0 15.9 15.4 9.3 21.5 10.7 13.6 15.3 7.6 23.2 7.4 16.2 17.1 21.0 7.2 11.2 8.2 18.1 19.1 7.5 16.6 19.6 14.8 16.3 17.4 15.0 8.3 39.0 22.6 9.1 3.6 15.1 21.3 8.2 15.3 10.6 17.5 35.6 21.2 14.9 52.5 5.7 8.8 10.9 10.6 21.2 24.7 36.8 107.9 24.7 16.2 13.9 19.6 18.9 17.3 19.9 18.7 20.1 32.9 16.1 19.2 16.6 16.5 30.4 21.1 23.1 12.5 24.6 28.1 22.5 52.6 22.0 14.6 14.0 29.7 18.0 38.5 24.6 15.9 90.2 26.0 23.4 22.9 55.0 26.6 20.0 23.9 102.5 11.8 22.1 14.9 29.6 15.9 11.2 34.2 52.1 31.9 30.9 20.7 57.6 16.8 34.0 27.1 18.8 28.3 42.6 21.3 10.3 27.8 54.1 30.8 10.8 15.5 27.1 30.7 2.8 2.7 2.3 2.6 2.1 1.8 2.6 3.2 3.7 2.4 1.8 2.8 2.0 7.2 1.4 2.7 3.9 3.6 2.1 17.2 17.8 20.3 19.0 16.2 17.1 18.1 19.1 17.4 15.3 21.2 21.2 48.5 28.9 33.5 15.0 18.7 45.9 115.0 81.1 26.7 35.6 47.6 28.7 11.5 55.8 63.2 40.5 25.0 51.2 42.6 35.0 35.2 82.7 285.9 85.3 26.5 56.0 26.0 4.6 5.7 93.6 47.0 33.5 55.0 56.3 17.7 32.5 50.3 8.3 43.7 21.9 6.8 29.3 67.1 27.9 39.7 163.0 37.3 34.9 35.6 9.4 52.0 42.6 22.6 4.5 12.0 136.6 36.2 36.9 23.2 77.1 57.9 53.3 80.6 59.5 52.6 42.9 70.9 63.5 53.2 23.2 47.5 142.7 33.2 26.0 25.4 139.2 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 CZIB "C1orf123, FLJ20580" ENSG00000162384 "CXXC motif containing zinc binding protein" Q9NWV4 1 53214099-53220634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 29.2;Cardiomyocytes: 45.8;Cytotrophoblasts: 60.7;Extravillous trophoblasts: 76.7;Fibroblasts: 22.2;Hofbauer cells: 66.5;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043835 Uncertain Approved "Vesicles,Mitotic spindle,Cytosol" Yes No 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Vesicles, Mitotic spindle" "HPA043835: AB_10796797" "unprognostic (1.09e-2)" "unprognostic (5.91e-2)" "unprognostic (2.03e-2)" "unprognostic (4.55e-2)" "unprognostic (5.43e-2)" "unprognostic (1.53e-1)" "unprognostic (9.20e-3)" "unprognostic (2.27e-1)" "unprognostic (5.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.46e-1)" "unprognostic (3.05e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (6.31e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (2.43e-1)" 55.8 35.5 56.1 22.3 58.0 21.9 49.4 57.2 74.6 53.6 56.9 66.5 22.5 57.1 39.8 32.3 52.3 30.2 52.5 57.7 56.6 39.4 43.5 33.1 30.0 57.9 56.6 47.2 25.1 34.6 28.5 30.6 57.0 41.0 34.8 21.6 24.8 45.4 76.5 26.2 31.6 59.2 57.1 32.5 40.3 31.0 57.4 36.3 35.1 65.3 29.7 57.7 37.6 59.0 32.6 34.7 44.7 41.0 101.6 129.1 39.4 47.8 50.4 47.3 50.8 29.6 27.5 50.1 39.0 58.1 45.8 12.6 27.9 46.9 57.0 65.0 47.5 51.0 24.9 45.0 100.0 59.5 32.1 84.6 50.3 50.6 53.3 71.5 78.5 61.0 53.7 13.7 60.1 54.6 73.5 55.6 74.8 39.7 54.3 52.8 56.8 39.7 55.8 32.6 37.6 36.1 45.1 40.9 47.7 72.2 29.2 59.8 49.3 54.5 31.9 38.2 47.2 19.5 30.7 57.3 43.9 58.5 42.8 60.7 56.6 58.6 50.9 72.3 46.9 46.9 49.8 53.6 68.8 45.1 55.0 54.9 22.8 59.0 60.3 46.3 68.2 51.1 56.1 58.0 57.2 74.6 57.7 56.6 57.9 56.6 57.0 57.1 57.4 59.0 29.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 60.7 8.2 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 76.7 22.2 0.0 0.0 0.0 0.0 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 46.7 1.3 0.0 0.0 0.0 DAAM2 KIAA0381 ENSG00000146122 "Dishevelled associated activator of morphogenesis 2" Q86T65 6 39792298-39904877 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 245.9" "Group enriched" "Detected in many" 5 "Astrocytes: 275.6;Oligodendrocytes: 449.8;Sertoli cells: 151.2" "Group enriched" "Detected in all" 5 "glioma: 15.0;melanoma: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 54.9;JURKAT: 30.4;LHCN-M2: 55.8;SK-MEL-30: 68.7;WM-115: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051300, HPA054630" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "HPA051300: AB_2681430, HPA054630: AB_2682549" "unprognostic (7.53e-2)" "unprognostic (6.02e-3)" "unprognostic (4.49e-2)" "unprognostic (7.93e-2)" "unprognostic (8.24e-2)" "unprognostic (4.28e-2)" "unprognostic (2.43e-2)" "unprognostic (1.05e-3)" "unprognostic (1.33e-1)" "unprognostic (5.89e-2)" "unprognostic (2.17e-1)" "unprognostic (5.24e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.67e-2)" "unprognostic (8.54e-2)" "unprognostic (7.94e-2)" "unprognostic (8.54e-4)" 33.7 22.5 179.4 9.0 229.4 1.8 23.3 175.8 159.3 15.7 65.1 18.9 9.8 14.0 10.4 36.6 18.5 7.4 13.5 144.0 170.5 9.3 4.8 12.4 3.6 234.8 195.8 10.0 7.5 4.1 5.1 12.2 205.0 11.0 8.7 1.6 7.6 21.7 38.3 8.5 20.9 18.3 194.3 40.2 18.9 12.3 187.7 2.5 13.1 38.1 2.3 9.9 11.3 245.9 0.1 0.0 5.8 0.1 12.2 0.3 0.2 9.8 13.1 2.2 1.2 0.9 0.0 0.1 0.5 14.7 4.5 0.1 0.0 0.0 0.8 0.0 2.4 0.0 0.0 0.1 8.8 0.0 0.1 54.9 0.0 0.3 0.0 15.6 0.0 30.4 0.0 0.1 55.8 0.2 1.5 0.1 1.6 3.1 0.1 0.0 10.0 8.1 0.0 0.0 2.0 2.3 0.0 0.7 68.7 11.7 0.0 0.1 0.6 20.8 6.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 179.4 229.4 175.8 159.3 144.0 170.5 234.8 195.8 205.0 194.3 187.7 245.9 11.2 9.6 12.2 275.6 0.1 1.8 0.9 0.0 0.0 1.3 1.5 1.5 2.5 1.5 3.8 0.0 0.0 0.5 0.1 0.0 0.0 0.5 3.8 1.2 10.4 9.0 0.0 2.7 1.4 3.3 0.5 11.8 0.5 2.3 0.0 1.9 2.5 1.2 0.2 0.0 5.8 0.0 0.0 31.5 2.4 6.4 23.6 6.2 8.8 21.5 0.0 5.8 1.0 8.5 449.8 0.3 0.0 22.2 0.0 0.8 0.0 0.1 1.5 1.6 151.2 12.7 48.8 1.0 1.9 0.4 1.1 0.3 0.7 55.9 0.0 1.2 DAB2 DOC-2 ENSG00000153071 "DAB adaptor protein 2" P98082 5 39371675-39462300 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Protein transport, Transport, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 179.1;placenta: 226.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1756.4;Proximal tubular cells: 1653.7;Syncytiotrophoblasts: 1324.5" "Cancer enhanced" "Detected in all" "renal cancer: 52.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 48.7" "Lineage enriched" "Detected in many" 8 "dendritic cells: 48.7" "Cell line enhanced" "Detected in many" "ASC diff: 220.1;ASC TERT1: 234.5;fHDF/TERT166: 356.8;TIME: 211.1;U-138 MG: 237.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009314, HPA028888" Enhanced Enhanced "Nucleoli fibrillar center,Vesicles,Plasma membrane" NA NA 130000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "Nucleoli fibrillar center" "CAB009314: AB_638976, HPA028888: AB_2672814" "unprognostic (1.24e-1)" "unprognostic (7.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (5.37e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.38e-6)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" 76.9 113.6 7.3 33.1 8.3 4.1 48.2 13.4 13.1 48.4 26.2 33.2 13.5 32.5 116.8 16.8 21.6 50.1 20.0 7.5 7.7 179.1 27.3 53.3 33.2 14.6 10.0 34.0 22.8 10.1 7.9 226.6 12.6 13.0 54.5 11.6 24.2 19.8 11.4 21.2 25.6 47.8 7.8 58.5 16.6 10.6 20.1 20.9 23.5 16.4 19.0 44.6 20.6 10.8 0.2 8.3 12.9 27.9 220.1 234.5 16.0 145.7 149.5 56.3 92.5 108.1 0.5 0.1 8.8 356.8 54.8 0.3 2.0 5.2 78.9 0.2 4.2 19.9 191.1 35.5 52.4 0.2 24.3 146.5 0.2 91.7 16.5 87.2 172.4 9.9 0.0 5.0 95.2 0.6 2.1 0.3 8.9 4.1 15.8 5.4 32.7 0.0 37.8 3.2 0.1 0.4 17.4 9.3 79.2 20.4 0.6 4.9 211.1 237.9 26.1 27.7 11.9 0.2 0.1 0.3 82.6 18.1 31.5 5.8 2.3 0.5 2.1 4.6 0.1 0.1 0.3 1.4 6.3 0.2 0.2 1.7 3.2 1.7 1.3 48.7 0.4 12.7 7.3 8.3 13.4 13.1 7.5 7.7 14.6 10.0 12.6 7.8 20.1 10.8 100.2 38.5 42.2 0.0 14.5 14.5 1.2 15.3 3.4 1.1 38.3 26.7 55.1 70.1 9.9 95.6 70.9 170.8 83.8 29.6 197.6 75.7 1.4 31.7 161.0 116.9 9.7 10.1 11.0 2.0 20.1 139.5 3.6 36.4 25.3 50.6 187.4 3.7 1756.4 8.4 2.8 7.6 2.0 175.2 77.9 4.5 122.4 287.4 12.4 92.8 10.9 81.5 63.8 27.2 0.3 6.5 10.2 64.3 1.4 7.0 33.8 1653.7 7.5 3.5 6.6 62.4 50.4 0.5 4.8 3.5 13.4 1324.5 13.4 104.8 27.5 1.3 DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468703-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 207.9;Skeletal myocytes: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 280.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 84000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" 25.2 22.0 31.5 17.9 32.6 5.4 26.6 30.7 30.7 26.2 25.5 38.8 24.0 32.1 16.2 28.3 31.8 26.4 68.9 30.1 28.9 28.1 43.0 31.8 9.4 33.3 31.4 24.6 51.4 44.3 18.6 77.0 28.6 29.5 30.6 9.8 31.8 37.9 93.8 28.5 24.0 45.9 30.2 12.6 32.0 26.9 34.1 10.5 25.5 95.7 14.3 27.8 22.0 31.2 92.3 92.4 61.9 152.3 80.3 38.8 280.9 63.9 93.7 108.0 69.0 74.2 96.0 13.0 62.2 103.2 87.6 168.4 55.6 81.2 67.2 12.7 18.6 9.6 84.3 87.2 35.5 11.2 17.4 33.3 72.5 100.3 33.3 96.7 97.1 15.3 14.5 9.8 31.2 75.5 10.1 8.1 66.4 110.0 31.2 5.5 60.5 22.3 82.5 126.4 21.8 45.2 74.8 206.0 105.5 170.3 171.6 22.8 51.8 39.1 63.9 76.0 91.4 11.0 24.2 8.1 50.4 12.6 245.9 2.3 1.2 0.7 1.1 1.3 1.2 1.2 0.9 0.9 0.7 1.0 1.0 1.0 2.2 1.1 2.5 1.3 0.7 1.4 31.5 32.6 30.7 30.7 30.1 28.9 33.3 31.4 28.6 30.2 34.1 31.2 19.0 54.5 18.4 32.0 4.0 14.3 8.0 31.7 17.1 7.4 36.1 46.4 56.6 30.0 20.6 35.0 4.2 116.4 5.8 37.3 1.9 32.4 30.0 30.2 17.3 20.9 33.0 14.3 15.6 79.6 118.4 26.1 37.8 37.9 7.0 207.9 16.8 59.9 21.2 3.3 16.5 29.7 14.2 8.6 7.0 20.0 21.5 6.3 33.8 9.4 5.6 27.1 5.2 19.6 10.7 57.2 21.4 36.9 5.1 14.4 18.9 7.6 23.2 8.7 46.0 326.1 36.2 7.1 19.9 19.0 17.0 95.9 5.9 10.0 29.2 10.2 DALRD3 FLJ10496 ENSG00000178149 "DALR anticodon binding domain containing 3" Q5D0E6 3 49015488-49022293 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 158.9;Late spermatids: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036862 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA036862: AB_10673507" "unprognostic (2.76e-2)" "unprognostic (8.44e-3)" "unprognostic (3.56e-1)" "prognostic favorable (9.03e-4)" "unprognostic (3.77e-1)" "unprognostic (1.52e-1)" "unprognostic (3.33e-3)" "unprognostic (1.19e-2)" "unprognostic (5.33e-2)" "unprognostic (9.52e-2)" "unprognostic (8.07e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.79e-5)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" 11.8 18.5 11.2 6.0 10.9 5.4 14.2 10.6 12.4 14.1 14.5 10.1 7.8 9.8 13.1 18.3 36.9 10.5 10.0 10.8 10.8 21.4 9.0 9.9 9.1 11.5 12.6 15.2 38.7 13.9 14.4 9.6 10.9 10.2 7.9 6.5 11.6 9.5 11.0 18.8 9.6 6.9 12.0 10.8 14.7 51.0 11.2 9.4 19.2 6.9 12.3 10.7 11.5 10.8 12.0 16.6 10.2 20.0 28.5 37.8 12.4 9.9 27.5 16.5 15.8 11.7 14.9 4.9 13.7 27.3 14.3 7.8 13.4 26.1 11.5 7.0 9.1 5.3 13.9 22.0 18.7 15.0 10.5 25.7 26.6 20.9 46.1 42.0 26.0 11.2 4.3 12.0 16.4 20.8 6.6 10.1 16.8 25.3 15.5 3.5 1.5 35.7 44.4 19.0 6.5 21.1 10.9 30.1 23.7 16.8 21.3 16.2 15.9 6.4 9.7 22.6 9.2 37.8 21.9 3.0 24.2 8.3 12.9 12.0 11.1 5.5 13.9 13.7 25.0 23.9 22.4 17.1 11.7 21.1 18.7 12.5 10.9 22.6 12.8 8.1 29.5 12.8 11.2 10.9 10.6 12.4 10.8 10.8 11.5 12.6 10.9 12.0 11.2 10.8 26.8 16.0 12.2 8.5 27.3 25.6 21.6 28.5 22.8 30.2 35.5 40.5 1.2 27.1 20.8 27.6 18.8 28.2 30.0 25.0 37.2 40.7 158.9 61.2 21.5 16.3 19.1 11.1 10.7 39.4 40.0 19.8 28.5 24.6 24.7 32.4 15.0 5.9 19.2 40.4 9.5 22.3 20.3 12.9 24.5 306.6 24.2 16.8 21.4 2.8 23.5 25.8 13.4 6.6 5.5 21.5 21.3 18.4 18.2 10.0 50.4 49.9 75.3 58.4 46.0 19.1 19.0 110.7 33.4 26.5 34.1 18.3 27.1 29.7 30.0 17.3 DAP ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Vesicles, Mitochondria" Nucleoplasm "HPA029456: AB_10601262" "unprognostic (2.70e-2)" "unprognostic (3.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (4.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "unprognostic (8.58e-3)" "unprognostic (2.04e-2)" 54.5 103.7 34.8 47.0 33.6 44.5 69.0 30.6 38.8 75.1 91.0 65.8 93.8 59.0 68.6 39.0 63.1 83.3 60.9 35.4 32.9 99.0 161.8 64.9 45.6 39.9 37.1 75.0 241.4 82.9 80.9 64.1 33.1 76.7 69.1 13.8 129.4 92.2 9.4 46.9 87.0 63.6 34.7 46.3 106.3 27.3 36.6 41.2 92.9 14.7 50.8 87.9 49.0 32.5 107.3 76.3 92.6 86.3 169.6 203.6 102.8 255.3 394.4 189.5 217.8 54.7 88.9 46.3 163.8 318.4 119.6 20.6 58.3 151.7 205.1 245.3 42.5 62.2 137.9 136.0 159.7 117.7 44.6 105.4 51.9 124.5 223.3 109.1 358.4 51.1 73.5 152.5 188.2 85.0 63.1 74.9 33.7 143.9 172.9 86.0 40.9 76.8 250.1 195.2 62.7 84.3 261.2 105.2 69.6 70.6 83.4 170.4 177.4 116.8 125.9 78.1 137.6 85.1 118.6 68.3 115.4 225.3 179.3 40.7 78.0 45.0 32.7 70.7 38.5 39.8 33.6 29.0 76.8 25.9 24.4 24.4 63.4 33.1 72.1 62.3 39.3 62.2 34.8 33.6 30.6 38.8 35.4 32.9 39.9 37.1 33.1 34.7 36.6 32.5 29.0 16.0 44.7 8.5 36.7 19.2 62.6 14.1 19.9 8.9 90.4 39.2 12.3 72.9 27.3 53.3 6.2 66.2 42.3 75.6 133.1 97.3 13.3 45.0 31.7 38.4 44.3 23.4 5.5 193.0 98.5 45.1 61.7 58.1 35.0 68.9 41.0 109.1 52.3 5.0 7.8 115.3 10.2 49.9 34.2 33.4 29.8 56.5 28.4 35.6 44.2 29.8 32.0 22.6 6.2 124.8 69.0 34.3 74.8 78.6 133.5 100.5 15.1 8.1 0.0 18.6 41.8 30.7 7.1 15.7 18.2 101.0 24.1 43.0 70.4 108.8 DAPL1 ENSG00000163331 "Death associated protein like 1" A0PJW8 2 158795317-158862781 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 196.9;esophagus: 242.0;skin 1: 301.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 212.9;Muller glia cells: 913.0;Squamous epithelial cells: 736.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 4.0;hTCEpi: 23.2;SCLC-21H: 5.9;U-87 MG: 8.4" "HPA046937, HPA058635" Enhanced Approved "Nucleoplasm,Nuclear bodies,Microtubules" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies, Microtubules" "HPA046937: AB_2679870, HPA058635: AB_2732625" "unprognostic (3.95e-5)" "prognostic favorable (8.43e-4)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (8.59e-2)" "unprognostic (5.24e-2)" "unprognostic (4.59e-2)" "unprognostic (2.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-3)" "unprognostic (4.09e-2)" "unprognostic (6.68e-2)" "unprognostic (3.00e-2)" "unprognostic (2.30e-3)" 1.9 56.0 1.6 0.1 1.8 0.8 28.7 1.6 6.6 47.6 1.2 2.9 0.5 0.6 196.9 242.0 80.5 0.6 0.5 1.3 9.3 3.6 0.2 1.6 0.6 1.5 5.3 1.0 22.8 0.0 24.4 0.1 2.4 9.2 0.7 115.6 30.2 1.1 1.0 301.0 1.0 0.5 1.3 0.3 1.5 1.5 4.3 4.8 34.3 0.0 25.0 8.6 108.1 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 0.1 0.2 23.2 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.4 5.9 0.0 0.0 0.0 0.6 0.0 0.7 1.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.0 1.2 0.8 0.5 0.1 0.6 0.2 0.4 0.2 0.1 0.3 0.4 0.1 0.1 0.5 0.7 0.1 1.2 0.4 0.1 1.6 1.8 1.6 6.6 1.3 9.3 1.5 5.3 2.4 1.3 4.3 1.2 0.6 0.0 0.0 0.0 4.1 106.9 51.8 74.8 212.9 7.2 15.0 19.6 0.1 2.8 29.8 9.2 6.2 6.0 4.9 2.0 3.9 7.6 13.8 5.6 2.2 2.0 3.0 0.0 0.2 6.0 12.8 2.4 0.0 5.4 4.5 148.1 0.7 14.3 14.7 3.3 0.4 2.0 14.2 9.1 9.3 56.1 4.1 5.0 12.4 0.0 5.4 913.0 2.1 1.0 0.1 5.8 7.1 2.2 3.4 11.8 5.9 13.3 4.8 23.8 0.0 1.9 10.9 10.8 4.2 736.5 126.6 4.5 3.1 1.7 2.3 67.4 DAW1 "FLJ25955, ODA16, WDR69" ENSG00000123977 "Dynein assembly factor with WD repeats 1" Q8N136 2 227871054-227924344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 25.7;fallopian tube: 32.6;testis: 51.3" "Group enriched" "Detected in some" 13 "Early spermatids: 106.7;Late spermatids: 215.3;Respiratory ciliated cells: 113.9;Spermatocytes: 177.1" "Cancer enhanced" "Detected in some" "lung cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HUVEC TERT2: 21.8;U-2197: 40.7" "Low region specificity" "Detected in many" HPA046118 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Plasma membrane" "HPA046118: AB_10961428" "unprognostic (1.23e-1)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (4.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.63e-3)" "unprognostic (2.90e-2)" "unprognostic (9.92e-3)" "unprognostic (1.54e-5)" "unprognostic (1.52e-1)" "unprognostic (6.83e-3)" "unprognostic (1.70e-1)" "unprognostic (3.08e-1)" 0.6 0.0 4.3 0.1 5.3 0.3 0.4 2.9 4.7 0.7 25.7 0.2 0.0 0.1 0.3 0.5 32.6 0.3 0.5 4.5 4.5 0.2 0.4 3.0 0.2 7.3 8.8 0.1 0.0 0.2 0.2 0.8 5.5 0.0 0.0 0.7 0.1 0.0 3.6 0.2 0.0 0.1 6.8 0.2 0.1 51.3 5.4 0.4 0.1 0.0 0.2 0.1 0.0 5.4 0.8 0.0 0.1 0.0 0.3 1.2 0.6 0.8 0.4 0.9 0.6 5.4 0.5 0.2 0.0 0.2 8.8 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.1 1.7 0.0 1.0 0.7 5.8 21.8 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.1 0.3 0.1 0.2 0.4 0.1 0.8 0.0 0.0 0.2 0.0 0.5 2.2 0.2 2.0 40.7 0.0 0.0 0.1 0.3 3.9 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.3 2.9 4.7 4.5 4.5 7.3 8.8 5.5 6.8 5.4 5.4 0.0 0.0 1.1 0.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.7 0.0 11.5 0.0 4.2 0.2 0.0 0.0 0.0 0.2 106.7 11.2 0.0 0.2 0.0 0.0 6.2 0.0 2.8 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 8.2 0.0 0.0 215.3 3.4 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.1 3.0 0.2 2.6 0.0 0.1 0.0 0.1 113.9 0.3 0.0 0.7 2.1 177.1 4.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 DBX2 FLJ16139 ENSG00000185610 "Developing brain homeobox 2" Q6ZNG2 12 45014672-45051099 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 9.3" "Group enriched" "Detected in some" 9 "Astrocytes: 11.4;Oligodendrocyte precursor cells: 14.1;Spermatogonia: 5.1" "Cancer enriched" "Detected in single" 32 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065045, HPA066053" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065045: , HPA066053: AB_2685605" "unprognostic (1.13e-4)" "unprognostic (9.99e-2)" "unprognostic (7.82e-3)" "unprognostic (5.24e-2)" "unprognostic (5.62e-2)" "unprognostic (1.51e-1)" "unprognostic (9.22e-2)" "unprognostic (4.76e-2)" "unprognostic (1.64e-1)" "unprognostic (5.19e-1)" 0.4 0.0 3.6 0.0 4.0 0.0 0.2 3.7 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.4 3.6 0.1 0.0 0.0 0.0 8.2 4.6 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 9.3 0.0 0.0 0.6 5.2 0.0 0.2 0.2 0.0 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.0 3.7 3.7 3.4 3.6 8.2 4.6 5.6 9.3 5.2 7.4 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 DCAF13 "DKFZP564O0463, Gm83, HSPC064, Sof1, WDSOF1" ENSG00000164934 "DDB1 and CUL4 associated factor 13" Q9NV06 8 103414714-103443453 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Ubl conjugation pathway" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044504 Uncertain Supported "Nucleoplasm,Nucleoli,Cell Junctions,Centrosome,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Centrosome, Cytosol" "HPA044504: AB_2678963" "prognostic unfavorable (4.06e-4)" "unprognostic (4.39e-2)" "unprognostic (1.70e-1)" "unprognostic (4.46e-3)" "unprognostic (3.57e-2)" "unprognostic (7.86e-3)" "prognostic unfavorable (8.05e-6)" "unprognostic (5.92e-3)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.54e-3)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (6.42e-2)" "unprognostic (8.63e-2)" 16.7 19.2 10.3 22.9 11.0 15.2 23.9 11.3 15.6 17.7 12.8 20.7 16.1 16.2 19.1 21.3 18.0 12.7 16.2 10.9 11.1 32.4 20.7 12.9 24.7 10.8 13.7 13.6 18.5 20.0 15.6 18.7 11.4 14.7 21.4 13.8 14.3 12.8 18.8 15.7 14.5 18.2 11.3 14.3 15.6 32.2 10.4 24.7 18.1 16.0 30.5 33.6 14.6 11.9 96.5 84.2 76.9 79.0 54.7 62.7 57.6 70.1 53.2 64.4 65.9 83.1 90.9 132.2 116.1 73.3 64.0 69.9 105.8 89.0 124.1 127.7 74.9 183.0 48.0 95.9 62.2 76.1 75.7 51.8 59.9 95.9 157.5 40.3 91.4 89.6 125.3 56.7 99.9 78.0 144.9 79.3 118.0 268.9 129.6 92.6 93.3 136.4 95.3 78.6 97.6 92.3 43.5 67.3 83.1 67.4 103.9 51.2 60.6 65.3 105.3 85.5 94.7 61.7 116.5 188.0 88.0 162.8 85.7 19.6 37.6 22.1 35.5 46.5 48.8 60.8 37.5 38.2 54.4 50.8 37.0 38.2 4.2 52.8 35.2 28.3 58.0 44.9 10.3 11.0 11.3 15.6 10.9 11.1 10.8 13.7 11.4 11.3 10.4 11.9 40.0 16.0 17.0 9.1 39.7 79.5 76.6 92.4 38.1 19.6 21.6 24.9 20.8 12.8 53.8 33.1 25.0 57.9 34.8 11.0 39.2 55.0 54.6 26.9 35.4 39.9 14.5 22.1 9.5 48.4 75.0 37.4 17.9 24.7 40.6 49.3 17.5 16.9 42.7 16.8 9.0 17.5 69.2 14.8 23.9 16.7 24.2 22.9 26.6 11.2 28.5 28.8 27.8 16.1 20.0 43.6 12.3 17.7 30.3 51.1 24.3 79.1 36.0 23.7 13.1 50.2 48.0 102.0 86.3 37.1 77.0 33.9 33.1 41.7 28.1 56.9 DCBLD2 "CLCP1, ESDN" ENSG00000057019 "Discoidin, CUB and LCCL domain containing 2" Q96PD2 3 98795941-98901695 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.8;Oligodendrocyte precursor cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 455.0;hTERT-RPE1: 648.9;LHCN-M2: 776.8;RPTEC TERT1: 479.0;U-87 MG: 581.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016909 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 2200000 "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA016909: AB_1847510" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-1)" "unprognostic (5.97e-3)" "unprognostic (9.29e-3)" "unprognostic (8.31e-3)" "unprognostic (1.06e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.32e-5)" "prognostic unfavorable (2.87e-4)" "unprognostic (7.76e-2)" "unprognostic (3.93e-2)" "unprognostic (1.59e-3)" 12.2 13.3 4.0 4.5 3.8 1.2 8.2 8.1 5.8 8.3 6.6 11.5 2.8 14.6 8.0 6.4 14.5 12.5 27.6 3.4 5.9 11.0 9.8 11.5 3.6 6.5 6.9 17.8 5.8 13.2 6.6 8.0 26.7 11.5 7.0 22.4 10.1 14.9 5.2 8.3 4.1 16.3 4.8 1.6 6.5 23.8 7.3 6.9 15.7 8.4 3.9 7.8 5.1 5.0 55.3 397.0 52.3 41.2 67.8 160.1 22.7 122.0 57.9 81.4 91.9 33.9 171.6 0.1 373.7 211.5 249.0 50.3 24.1 198.8 186.2 0.8 8.4 19.4 12.1 51.5 41.6 9.3 8.7 63.8 30.3 234.3 455.0 648.9 54.6 7.1 4.0 5.0 776.8 14.6 7.7 5.5 36.5 0.4 135.6 8.1 98.2 4.8 479.0 14.4 14.0 24.3 33.5 6.9 145.9 35.2 26.4 7.3 90.4 208.0 166.6 53.8 433.0 6.3 9.7 7.4 581.3 3.4 92.8 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.0 3.8 8.1 5.8 3.4 5.9 6.5 6.9 26.7 4.8 7.3 5.0 5.9 32.1 52.8 18.3 2.7 22.8 15.5 18.2 17.1 12.9 15.5 16.3 83.8 17.2 19.0 18.4 77.2 12.4 1.6 4.3 0.0 30.5 3.1 32.2 39.5 7.7 3.6 5.9 51.6 8.0 9.7 33.8 6.1 38.3 38.0 52.2 6.8 20.5 4.0 13.5 51.3 8.0 20.3 3.2 6.2 5.8 22.1 4.0 8.8 25.3 1.4 40.9 2.1 88.4 38.9 26.3 4.6 50.4 1.6 11.9 0.7 7.9 22.8 48.9 0.0 12.3 31.3 15.8 24.2 14.1 15.6 4.0 1.8 34.4 8.2 7.1 DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Collecting duct cells: 79.1;Distal tubular cells: 56.7;Ductal cells: 135.9;Endometrial ciliated cells: 160.3;Glandular and luminal cells: 102.4;Proximal tubular cells: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 71.8;EFO-21: 48.3;Hep G2: 82.3;RPTEC TERT1: 254.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" 0.0 1.3 0.8 0.0 1.2 0.1 4.4 0.3 0.8 1.6 15.1 0.7 0.6 4.4 5.3 0.0 7.6 3.9 0.0 0.8 1.0 23.2 2.2 3.4 0.0 2.2 2.7 0.2 26.2 8.2 1.2 0.6 1.7 1.2 0.6 1.4 0.4 2.3 0.3 0.1 0.1 0.1 2.0 0.1 1.8 3.7 1.1 0.1 8.2 0.2 0.0 0.4 0.0 1.6 0.0 8.8 0.5 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 71.8 0.2 0.0 48.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.2 0.0 0.0 82.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.4 0.0 0.2 0.1 0.0 0.3 10.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 254.5 0.3 5.2 0.5 0.0 1.3 0.0 0.2 12.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.2 0.3 0.8 0.8 1.0 2.2 2.7 1.7 2.0 1.1 1.6 0.2 19.2 14.4 3.9 1.4 0.1 0.6 0.3 0.0 0.0 20.3 11.7 0.3 62.9 6.1 79.1 0.0 0.4 0.0 1.2 56.7 135.9 40.1 160.3 5.3 0.4 3.6 0.0 11.3 8.4 0.0 1.3 3.6 102.4 0.0 4.1 0.0 1.0 0.5 0.0 8.3 2.9 0.0 0.0 0.0 14.6 0.3 1.0 0.0 1.0 2.0 2.3 0.0 1.0 0.5 27.9 4.1 0.4 0.0 1.3 0.0 54.3 37.1 0.1 0.0 0.0 2.4 32.3 2.6 0.0 0.1 0.1 1.1 5.6 2.7 0.9 DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113022195 "Enzymes, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: AB_731858, HPA057676: AB_2683500" "unprognostic (2.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-3)" "prognostic unfavorable (4.84e-4)" "unprognostic (1.87e-1)" "unprognostic (3.64e-2)" "unprognostic (6.26e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-2)" "prognostic unfavorable (2.66e-5)" "unprognostic (8.39e-2)" "unprognostic (2.84e-1)" "unprognostic (3.25e-2)" "unprognostic (5.75e-2)" 4.6 4.0 5.9 8.1 6.0 14.0 6.9 9.8 5.7 6.0 6.6 3.9 3.7 4.3 3.4 4.1 4.7 3.5 3.4 5.9 7.2 4.8 4.7 6.9 12.6 5.5 4.9 6.7 3.3 3.1 3.7 12.1 5.8 4.4 4.1 7.4 5.3 3.5 4.8 5.8 5.1 3.3 4.5 10.2 4.0 3.8 8.5 17.9 3.7 3.9 12.3 4.4 5.2 5.1 6.4 5.6 24.1 19.0 4.5 5.3 37.0 6.7 4.3 7.2 9.8 25.0 13.1 32.2 8.5 3.2 5.6 7.9 27.6 7.1 8.8 9.0 11.0 29.5 4.6 9.9 5.4 20.1 15.3 4.8 5.3 8.4 9.0 6.9 12.5 24.8 22.7 12.0 6.1 8.1 29.6 19.6 20.8 4.0 2.9 27.0 22.7 12.2 10.5 15.4 5.6 11.4 8.3 8.8 11.3 24.1 25.3 24.4 7.7 7.8 13.9 4.4 8.8 8.8 19.8 23.6 4.7 26.0 6.3 14.0 4.9 3.7 3.0 6.1 4.2 3.8 3.7 3.0 5.1 2.5 3.4 3.7 9.4 3.5 7.3 2.9 4.3 2.6 5.9 6.0 9.8 5.7 5.9 7.2 5.5 4.9 5.8 4.5 8.5 5.1 30.0 19.2 16.8 16.0 50.7 27.8 19.9 22.3 31.9 24.7 43.5 26.4 12.4 8.6 24.1 20.2 79.2 66.7 65.0 11.6 19.6 11.2 24.3 21.7 38.1 28.9 16.2 41.9 25.5 11.8 49.6 25.7 17.3 25.7 19.6 66.7 28.5 7.0 31.7 28.6 34.1 8.9 20.3 78.1 41.5 53.8 19.0 57.4 26.6 56.2 90.7 36.9 35.0 26.7 28.8 17.3 10.6 10.9 27.1 33.3 13.8 14.4 22.7 34.6 6.6 16.5 32.3 36.6 29.5 20.0 26.6 64.4 50.1 52.0 13.1 48.8 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" "Plasma membrane" "HPA024049: AB_1847524, HPA024558: AB_1847525" "unprognostic (1.28e-1)" "unprognostic (8.32e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-2)" "unprognostic (9.26e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.43e-1)" 50.6 54.1 48.0 26.6 51.1 43.7 53.0 51.8 74.1 32.3 42.3 37.5 23.8 38.2 43.5 34.3 30.1 32.8 75.6 50.4 54.8 54.2 46.7 34.0 28.3 50.8 49.8 41.5 32.0 72.8 29.7 53.6 51.1 34.7 36.2 42.4 33.6 36.7 36.6 29.0 26.1 42.6 52.9 27.6 31.9 21.9 50.5 37.8 54.6 43.5 31.2 45.8 31.6 58.6 53.6 51.9 64.4 33.8 59.3 80.7 42.1 72.8 87.0 70.4 74.9 33.6 35.8 41.0 76.0 78.8 64.9 39.6 46.1 64.2 83.8 32.4 34.3 57.8 40.9 54.5 45.8 33.6 47.4 68.2 90.4 51.2 54.8 61.5 65.2 58.0 66.4 44.3 77.0 41.7 62.4 53.0 51.6 93.8 32.0 32.4 48.7 35.3 104.6 54.1 105.4 60.0 42.7 53.0 77.9 32.4 50.4 48.3 60.8 37.4 128.9 31.9 52.4 18.1 22.2 51.8 69.7 38.1 68.1 16.7 13.5 5.0 8.1 15.8 9.1 7.1 7.5 9.8 15.9 5.3 9.5 11.4 3.7 11.2 15.9 20.8 8.1 6.8 48.0 51.1 51.8 74.1 50.4 54.8 50.8 49.8 51.1 52.9 50.5 58.6 61.3 25.6 39.7 19.9 34.9 57.2 91.3 127.1 25.6 36.4 45.4 43.2 83.4 47.1 85.3 44.1 14.6 88.5 48.9 28.1 123.3 94.5 18.0 32.5 37.2 58.7 40.8 28.2 19.0 84.5 87.7 56.6 25.0 39.6 46.9 44.0 45.7 42.7 71.4 26.9 17.3 31.6 91.6 43.9 54.8 12.5 80.8 43.2 69.4 15.0 58.4 63.3 17.5 17.6 21.3 91.1 43.1 75.2 32.3 48.8 36.3 147.1 71.6 40.3 52.6 63.1 66.0 44.2 47.3 38.0 63.5 203.6 59.8 49.5 33.0 95.0 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 131.8;kidney: 124.8" "Cell type enhanced" "Detected in many" "Astrocytes: 364.4;Excitatory neurons: 197.4;Oligodendrocyte precursor cells: 182.4;Proximal tubular cells: 283.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 239.4;LHCN-M2: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006308, HPA071064" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 350000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532, HPA071064: " "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favorable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favorable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 10.3 28.6 95.9 12.8 100.9 0.6 18.8 61.5 131.8 22.4 73.4 45.1 40.1 10.8 76.5 12.6 36.5 25.5 17.4 102.0 77.3 124.8 79.5 26.4 2.6 58.6 84.8 2.9 27.5 21.1 6.3 11.6 62.6 28.5 45.3 34.6 17.7 18.6 30.4 5.6 39.7 16.5 59.5 10.6 29.7 19.1 106.6 1.0 28.9 14.0 2.0 19.2 2.6 80.3 63.1 7.6 36.0 6.9 84.1 78.0 9.2 155.9 120.0 63.6 75.6 89.9 16.5 0.1 39.2 239.4 38.3 17.8 79.7 15.0 93.0 0.3 29.5 0.2 22.3 31.8 40.9 57.6 3.2 60.5 2.0 50.4 24.9 85.5 75.9 0.0 0.1 6.0 179.7 7.5 3.0 0.3 25.5 124.6 22.6 0.0 63.1 0.9 113.4 46.3 59.2 115.0 18.0 56.3 9.1 38.7 29.6 4.9 107.7 31.6 27.0 11.7 57.8 0.0 0.1 0.2 1.6 0.1 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.9 100.9 61.5 131.8 102.0 77.3 58.6 84.8 62.6 59.5 106.6 80.3 14.1 35.3 43.4 364.4 2.6 13.8 4.6 6.8 5.7 4.5 31.2 13.8 11.8 61.5 13.6 69.9 4.2 2.7 0.4 75.3 125.2 15.9 22.5 36.9 9.8 7.5 34.2 2.7 197.4 31.2 0.9 13.9 47.9 24.2 0.0 59.3 8.2 102.8 1.1 0.0 51.0 86.9 8.2 2.2 5.5 25.6 15.8 2.4 12.4 23.4 0.6 68.4 0.0 182.4 9.6 44.5 69.4 74.9 0.0 33.6 68.7 283.3 36.5 9.4 13.1 15.3 18.6 4.6 5.4 32.6 14.3 0.8 2.5 13.5 106.7 8.3 DDIT4L "REDD2, Rtp801L" ENSG00000145358 "DNA damage inducible transcript 4 like" Q96D03 4 100185870-100190782 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 323.5;tongue: 106.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Distal tubular cells: 21.5;Extravillous trophoblasts: 18.5;Granulosa cells: 23.5;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 19.3;BJ: 29.6;fHDF/TERT166: 16.2;HSkMC: 14.7;hTERT-RPE1: 32.8;RPTEC TERT1: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050903 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA050903: " "unprognostic (2.21e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.77e-4)" "unprognostic (1.66e-3)" "unprognostic (5.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.12e-1)" "unprognostic (3.21e-1)" "unprognostic (7.18e-2)" "unprognostic (2.59e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-2)" "unprognostic (4.82e-3)" "unprognostic (2.09e-2)" "unprognostic (7.53e-5)" "unprognostic (4.99e-3)" 3.1 1.0 7.0 0.6 21.1 0.4 2.2 8.5 11.0 23.0 7.7 2.0 0.3 1.5 1.7 7.7 2.1 0.6 2.3 10.2 7.6 21.8 0.4 0.8 0.5 11.8 8.8 7.7 0.4 0.6 2.0 3.7 11.1 11.2 0.9 1.2 17.4 6.9 323.5 1.1 0.7 1.6 9.1 1.2 0.5 3.0 8.7 1.2 1.1 106.9 0.4 1.2 2.6 8.9 0.0 2.2 8.5 0.0 3.7 19.3 1.2 29.6 2.5 0.5 0.1 0.1 0.9 0.0 0.7 16.2 0.7 0.0 6.2 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 14.7 0.1 0.3 1.5 32.8 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.7 0.0 0.0 0.6 0.0 0.0 20.5 0.1 0.1 0.1 0.6 1.2 4.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 2.3 3.9 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.0 21.1 8.5 11.0 10.2 7.6 11.8 8.8 11.1 9.1 8.7 8.9 3.8 0.0 0.0 6.2 0.0 2.7 0.2 4.2 1.8 0.1 1.0 0.9 7.3 0.0 1.3 22.0 0.0 1.9 0.4 0.2 21.5 0.1 0.8 0.5 0.3 3.6 0.0 0.0 0.0 0.0 18.5 5.1 1.5 0.9 0.0 23.5 0.0 0.0 12.0 0.0 0.5 0.3 0.0 0.0 3.0 0.4 0.9 0.3 7.2 0.0 0.0 8.6 0.0 0.5 0.0 0.5 0.0 2.2 0.2 1.1 0.0 2.2 0.1 0.2 19.7 7.3 11.9 4.7 0.8 0.9 1.4 4.0 0.6 8.3 0.4 0.3 DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814691-117832377 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 376.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 17000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA035400: AB_10672091, HPA041056: AB_2677277" "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (2.06e-1)" "unprognostic (1.77e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (8.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (7.28e-2)" "unprognostic (5.65e-2)" 25.3 21.4 14.9 30.2 15.9 21.8 32.7 16.1 18.0 23.4 15.1 28.3 22.4 30.0 22.9 24.8 23.6 22.2 21.2 14.1 15.9 27.0 35.2 24.8 41.1 15.7 15.2 25.5 21.1 21.4 10.8 26.2 16.1 23.2 31.0 19.4 19.3 23.0 18.6 22.9 23.4 26.3 16.6 32.3 22.8 20.6 15.1 34.5 30.2 18.3 41.7 33.2 17.3 19.0 94.0 41.9 61.3 55.5 35.5 31.9 101.0 54.7 43.0 73.7 64.6 104.2 60.6 137.8 85.9 45.6 68.0 71.1 120.3 70.7 108.0 70.6 83.9 132.0 36.9 105.1 49.5 178.4 66.0 33.4 63.9 93.7 94.3 37.6 44.9 70.3 146.5 58.4 57.1 58.6 98.2 92.6 154.4 79.1 62.3 84.4 95.8 121.3 48.8 55.2 58.8 99.3 62.7 69.2 73.4 62.1 43.9 96.7 34.9 65.6 96.5 46.8 99.5 66.3 87.9 376.0 48.2 82.9 30.1 11.7 23.0 16.3 24.9 28.9 32.0 37.4 29.8 28.9 20.7 30.3 35.6 31.7 5.8 29.7 33.1 33.7 25.7 32.1 14.9 15.9 16.1 18.0 14.1 15.9 15.7 15.2 16.1 16.6 15.1 19.0 144.4 96.1 62.5 24.8 153.9 192.7 114.4 149.4 100.2 150.5 82.8 94.5 50.4 101.5 103.8 121.4 83.4 110.3 140.6 69.0 117.4 125.4 17.1 92.2 125.1 109.1 56.9 76.4 24.3 115.2 120.9 98.2 63.2 102.8 110.3 71.8 107.1 195.6 87.9 82.4 28.0 108.0 109.9 104.8 100.8 17.7 106.6 100.6 92.5 20.6 117.1 70.3 135.9 26.7 39.1 130.0 68.8 103.8 103.3 118.1 53.3 186.5 90.6 132.9 65.7 158.7 110.1 138.6 129.9 81.4 160.5 88.8 143.2 67.4 114.6 65.3 DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111754832-111775602 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 52.8" "Group enriched" "Detected in all" 5 "Early spermatids: 738.2;Late spermatids: 718.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "CAB015427: AB_629518, HPA005516: AB_1849612" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "prognostic favorable (9.85e-5)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (6.35e-6)" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (7.46e-3)" "unprognostic (4.21e-1)" "unprognostic (5.22e-2)" "unprognostic (1.05e-3)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (1.30e-2)" 4.6 3.6 0.8 1.3 0.7 2.3 4.3 0.4 0.9 4.2 0.3 3.9 0.5 4.8 0.9 3.3 4.5 1.6 3.6 0.8 0.7 3.0 2.6 3.2 3.0 0.7 0.8 4.3 3.6 2.5 1.9 2.4 0.5 3.0 1.9 0.8 3.3 2.5 8.8 3.6 4.3 2.8 0.5 4.8 3.8 52.8 0.6 3.7 3.2 1.8 4.2 4.0 3.3 1.3 7.0 3.8 7.1 7.3 4.7 5.0 7.0 3.3 9.1 16.3 18.6 5.8 4.5 17.7 5.2 6.4 3.9 5.8 13.5 9.4 18.2 7.3 9.2 7.4 3.2 3.0 4.6 8.4 6.1 3.0 10.4 9.2 12.2 2.4 12.8 7.2 10.8 5.9 12.0 6.5 11.8 0.9 14.1 5.2 8.5 11.3 12.7 5.3 4.8 5.2 11.7 9.5 6.7 7.0 12.7 5.7 7.0 8.5 3.5 7.9 8.2 13.2 8.6 1.2 5.3 12.3 7.5 8.1 18.5 14.9 6.2 6.0 8.2 5.6 10.7 9.3 9.1 8.4 6.8 9.1 10.6 8.6 3.4 9.1 6.6 3.5 10.0 6.9 0.8 0.7 0.4 0.9 0.8 0.7 0.7 0.8 0.5 0.5 0.6 1.3 8.5 12.8 9.4 6.8 13.0 10.8 9.7 6.0 9.6 14.3 6.5 6.6 7.7 5.7 10.0 5.5 2.1 10.2 9.4 2.9 3.9 9.5 738.2 8.1 12.0 9.3 4.2 5.9 7.4 6.9 7.5 6.9 5.1 5.4 7.6 12.3 5.7 5.9 9.3 6.7 7.7 5.8 8.2 7.2 7.0 718.9 16.4 7.3 1.8 3.7 7.5 6.9 6.2 3.0 3.6 6.3 2.3 13.2 9.0 5.2 3.0 7.6 11.8 10.4 6.6 9.7 11.7 121.7 26.3 7.0 7.2 5.1 11.1 14.0 6.6 5.5 DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956170-68985068 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 589.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 40000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA036592: AB_10673625, HPA036593: AB_2675208" "unprognostic (3.04e-1)" "unprognostic (6.81e-3)" "unprognostic (1.13e-2)" "unprognostic (1.21e-2)" "unprognostic (1.75e-2)" "unprognostic (6.71e-3)" "unprognostic (1.34e-2)" "unprognostic (1.99e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (3.12e-4)" "unprognostic (1.64e-1)" "unprognostic (1.39e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-2)" "unprognostic (1.24e-2)" "unprognostic (5.74e-3)" 55.9 27.9 7.9 52.7 8.8 103.5 36.2 8.9 9.3 22.0 7.7 26.5 25.5 25.2 13.4 40.3 24.0 32.4 21.9 7.4 9.7 30.0 42.1 31.5 50.0 10.8 10.1 20.1 45.7 24.5 12.9 38.0 11.0 19.0 32.0 8.1 20.5 17.5 47.9 30.1 21.8 28.4 10.7 30.2 26.4 22.5 8.8 33.6 25.1 26.9 51.0 81.7 23.5 11.3 194.4 112.5 64.5 199.7 56.7 74.4 135.6 129.8 104.3 163.8 138.3 366.7 128.8 289.5 77.8 108.2 77.2 168.1 250.4 161.8 217.5 90.7 176.1 203.2 76.9 153.3 121.2 488.9 184.7 76.8 205.2 196.2 324.5 76.1 121.3 106.8 393.8 140.5 116.8 88.1 192.9 106.1 176.3 91.8 236.8 170.1 105.3 143.0 108.2 102.7 132.5 141.6 116.6 254.8 155.5 76.8 144.9 101.1 125.6 95.5 136.0 129.8 230.7 160.4 228.2 418.2 79.3 362.4 66.5 7.6 10.9 20.4 8.7 17.1 15.9 14.0 11.4 11.8 13.0 12.3 10.6 11.8 4.9 9.4 21.2 12.1 9.2 7.5 7.9 8.8 8.9 9.3 7.4 9.7 10.8 10.1 11.0 10.7 8.8 11.3 199.4 102.5 141.6 8.1 243.7 550.2 346.2 103.8 174.2 25.9 159.9 113.7 74.2 94.4 144.1 71.7 41.7 80.8 139.5 134.0 72.4 141.2 50.8 116.7 260.7 196.7 86.7 98.6 18.5 187.8 151.8 162.2 120.8 201.8 168.5 57.1 104.2 215.3 112.4 25.2 16.0 202.7 67.1 154.5 266.8 19.7 89.5 199.1 124.5 12.2 138.1 25.8 64.9 13.6 18.2 222.9 77.7 77.1 148.9 465.3 59.9 128.2 72.8 29.8 26.3 302.6 174.9 105.5 114.8 224.8 589.7 137.5 159.6 99.4 210.7 375.5 DDX28 "FLJ11282, MDDX28" ENSG00000182810 "DEAD-box helicase 28" Q9NUL7 16 68020916-68023232 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041911, HPA053585" Approved Supported Nucleoli,Mitochondria,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" Nucleoli "HPA041911: AB_10794161, HPA053585: AB_2682200" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.58e-1)" "unprognostic (8.69e-2)" "unprognostic (8.46e-2)" "unprognostic (9.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.63e-2)" "unprognostic (8.14e-3)" "unprognostic (8.53e-2)" "prognostic favorable (2.07e-10)" "unprognostic (1.58e-2)" "unprognostic (6.21e-2)" "unprognostic (2.23e-1)" "unprognostic (2.47e-1)" 5.8 10.0 3.9 4.8 4.1 16.8 5.6 4.0 4.3 3.9 4.0 5.7 3.9 6.0 5.1 8.2 5.0 2.8 8.3 4.1 4.7 6.4 8.7 4.3 7.7 4.0 3.9 5.5 5.6 7.0 3.6 4.7 4.3 3.5 4.3 1.6 5.0 3.5 15.4 9.7 7.0 3.7 4.0 9.0 6.3 9.7 4.1 5.6 4.0 7.7 6.4 5.5 4.3 4.1 10.2 14.7 7.1 8.5 9.5 5.3 16.5 6.9 9.8 16.4 11.6 14.4 15.5 37.6 10.2 8.3 9.0 17.9 10.1 16.1 9.6 5.1 16.7 13.6 7.4 14.9 12.8 21.7 14.1 10.3 17.2 13.5 12.4 5.7 9.2 24.9 24.5 5.7 7.4 22.4 22.9 30.0 17.2 10.2 10.7 22.1 6.6 40.3 11.6 11.4 14.8 9.9 27.6 7.8 15.3 8.0 14.9 23.1 7.0 7.3 6.3 10.6 11.2 12.8 16.9 36.7 9.0 16.4 10.1 24.0 22.3 27.4 17.0 22.4 18.7 14.3 15.6 18.5 20.8 19.0 24.2 18.2 7.2 21.5 23.4 10.2 16.0 20.8 3.9 4.1 4.0 4.3 4.1 4.7 4.0 3.9 4.3 4.0 4.1 4.1 4.4 6.4 6.8 0.7 10.9 9.2 14.2 11.7 8.0 5.6 4.8 4.3 4.1 8.6 8.3 3.7 0.0 27.9 4.0 2.9 13.7 12.0 6.6 5.4 4.4 5.7 4.8 9.5 0.9 9.7 12.5 4.4 5.1 5.4 3.8 8.0 6.8 11.6 17.1 3.3 1.0 3.5 6.1 8.5 3.1 4.0 5.0 6.8 7.2 0.0 13.3 7.5 25.7 0.5 1.4 7.4 4.2 3.4 4.2 5.7 2.0 19.7 5.3 4.3 13.1 4.4 9.4 22.7 14.1 6.7 10.7 99.9 7.6 12.5 6.1 8.8 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 3.9 3.8 3.3 5.3 3.9 4.2 6.3 8.8 3.2 4.8 4.0 3.9 3.1 4.5 5.0 5.7 5.2 3.6 3.3 2.8 3.7 6.0 5.5 4.5 6.6 5.1 3.8 9.9 5.8 5.4 4.2 3.5 5.7 5.4 4.7 3.2 8.2 4.3 6.1 8.4 4.2 4.2 2.9 4.8 4.0 6.0 3.6 5.5 13.8 4.2 7.2 5.2 4.9 4.7 12.4 22.2 10.8 14.4 12.4 11.1 20.4 12.9 12.2 19.2 14.5 24.9 24.1 29.9 11.2 11.7 20.8 33.5 32.8 14.6 15.4 18.4 12.3 16.4 19.5 13.1 14.9 29.7 12.8 9.9 19.5 19.7 27.5 7.5 12.7 22.1 30.6 11.4 16.1 26.3 20.6 15.9 26.2 35.4 22.2 21.4 19.3 34.6 17.5 11.4 18.8 13.5 23.4 20.2 18.0 12.2 42.8 8.4 11.1 32.5 15.0 18.7 19.8 5.5 18.8 23.5 12.0 18.2 25.2 0.0 1.1 1.2 3.1 1.6 2.4 2.1 2.9 2.4 2.5 2.7 3.6 2.7 0.2 2.0 1.1 1.6 2.0 1.7 3.3 3.9 8.8 3.2 2.8 3.7 5.1 3.8 5.7 2.9 3.6 4.7 3.3 6.4 6.0 16.6 7.2 5.6 4.5 3.0 9.1 4.3 5.9 8.1 4.4 0.0 10.2 7.3 4.2 5.7 4.7 3.6 1.9 6.2 4.1 3.9 6.6 3.6 24.6 1.7 9.7 5.4 6.8 4.4 4.1 4.6 1.3 6.1 2.9 4.1 5.2 1.7 13.9 5.8 6.1 2.9 1.8 3.0 18.0 2.9 1.8 5.6 4.5 1.7 8.2 26.7 17.1 5.9 1.2 13.2 5.7 5.8 0.7 7.1 5.7 3.7 0.0 4.1 3.4 14.0 13.7 8.8 6.3 3.0 5.0 5.7 6.1 3.5 DDX4 VASA ENSG00000152670 "DEAD-box helicase 4" Q9NQI0 5 55738017-55817157 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "testis: 149.7" "Group enriched" "Detected in some" 4 "Early spermatids: 565.1;Late spermatids: 184.1;Spermatocytes: 320.9" "Cancer enriched" "Detected in single" 37 "testis cancer: 3.0" "Region enhanced" "Detected in single" "white matter: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.8;PC-3: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026170, HPA037763, HPA037764" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "CAB026170: , HPA037763: AB_2675652, HPA037764: AB_2675653" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.54e-1)" "unprognostic (2.58e-1)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (5.35e-2)" "unprognostic (3.91e-1)" "unprognostic (3.77e-2)" "unprognostic (3.28e-1)" "unprognostic (5.73e-2)" "unprognostic (5.43e-7)" "unprognostic (4.84e-2)" "unprognostic (1.12e-1)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 149.7 0.3 0.3 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.2 0.1 0.3 0.1 0.2 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 565.1 0.0 0.0 0.4 0.0 0.0 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 12.2 0.0 0.0 184.1 5.6 0.5 0.0 1.0 0.0 0.0 0.0 1.5 8.7 0.1 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 320.9 83.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DDX51 ENSG00000185163 "DEAD-box helicase 51" Q8N8A6 12 132136594-132144319 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039503 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" Cytosol "HPA039503: AB_10796328" "unprognostic (2.84e-3)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-1)" "unprognostic (8.66e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (4.88e-1)" "unprognostic (3.05e-3)" "unprognostic (5.31e-2)" "unprognostic (3.97e-2)" "unprognostic (2.48e-1)" "unprognostic (4.69e-2)" "unprognostic (3.28e-1)" "unprognostic (1.65e-3)" 8.5 7.1 4.6 1.9 4.7 4.3 8.6 4.5 5.8 9.7 3.3 8.6 1.6 8.5 2.4 7.2 10.5 1.0 6.8 4.8 4.0 9.3 6.9 6.8 2.5 4.5 4.3 12.9 11.2 1.9 8.7 1.3 4.7 8.7 1.4 2.6 6.9 2.3 9.7 12.0 8.0 1.7 4.2 9.6 8.1 6.7 4.2 2.3 8.5 1.4 1.9 9.3 8.0 5.1 4.1 6.5 2.7 3.4 2.5 2.4 5.0 3.1 1.8 4.5 1.9 4.0 2.0 7.2 2.6 1.9 1.0 4.2 6.7 5.0 2.2 1.7 6.5 8.5 3.8 1.3 3.0 6.0 4.7 2.1 3.6 2.5 2.3 5.0 2.4 7.8 6.4 2.3 1.3 4.1 7.4 12.2 4.7 3.4 11.0 8.6 3.6 7.9 3.1 3.2 6.5 3.4 3.4 4.8 3.5 2.2 4.2 5.5 4.2 1.7 5.1 4.1 7.2 6.4 4.0 8.2 3.5 4.5 4.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.1 4.6 4.7 4.5 5.8 4.8 4.0 4.5 4.3 4.7 4.2 4.2 5.1 9.5 3.2 17.3 5.2 8.4 12.5 10.1 2.9 7.4 28.5 9.9 10.4 4.5 10.0 9.0 3.7 25.0 6.7 12.9 7.6 1.9 4.1 1.0 6.4 9.2 8.6 8.4 5.0 22.1 5.3 6.4 9.5 9.7 8.8 6.3 18.2 6.8 7.3 5.6 33.7 17.1 11.1 0.0 6.3 8.0 1.1 8.4 6.4 10.6 11.2 4.6 11.7 11.3 8.0 9.0 6.0 8.0 8.2 8.4 11.3 3.3 3.4 4.4 28.0 0.0 17.7 9.1 7.0 11.1 6.3 14.1 4.1 11.1 17.2 12.8 6.8 DDX53 "CAGE, CT26" ENSG00000184735 "DEAD-box helicase 53" Q86TM3 X 22999960-23003589 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 38 "brain: 2.1;testis: 5.4" "Cell type enriched" "Detected in some" 5 "Early spermatids: 62.6" "Cancer enriched" "Detected in single" 4 "testis cancer: 0.7" "Region enriched" "Detected in single" 7 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.2;K-562: 4.6;RPMI-8226: 2.4;U-2197: 1.4;U-266/84: 10.5" HPA003186 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nucleoli, Cytosol" "HPA003186: AB_1078637" "unprognostic (5.76e-1)" "unprognostic (1.12e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.3 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.1 0.2 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 10.9 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DDX54 "APR-5, DP97, MGC2835" ENSG00000123064 "DEAD-box helicase 54" Q8TDD1 12 113157173-113185479 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028244, HPA070786" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA028244: AB_10603885, HPA070786: AB_2686311" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (8.54e-2)" "unprognostic (8.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (2.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.83e-2)" "unprognostic (1.15e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" 19.6 21.7 7.4 28.9 8.6 38.8 18.7 8.0 9.7 20.0 12.0 17.9 26.8 21.4 5.6 24.0 21.1 13.3 17.8 7.4 7.3 16.2 20.8 17.0 28.5 8.9 8.1 23.2 30.3 20.7 8.4 16.8 9.3 16.2 11.4 7.3 19.7 15.8 53.9 24.7 21.0 13.5 7.7 21.5 21.8 9.2 9.2 21.3 19.0 20.4 16.5 19.9 18.2 9.0 82.7 84.0 30.8 57.1 20.2 24.1 79.3 43.8 40.3 58.3 31.9 87.1 39.0 105.8 49.7 36.8 43.4 59.8 55.0 56.8 22.0 61.3 67.7 64.0 45.1 60.3 35.3 107.5 72.1 39.8 44.1 56.7 34.7 47.7 48.4 63.2 94.2 37.1 30.4 75.8 93.0 152.4 72.1 57.6 59.2 68.2 45.6 107.8 31.7 84.3 39.8 36.0 61.8 93.4 39.9 25.2 80.4 82.6 36.3 49.2 54.8 59.1 92.7 53.3 66.4 119.5 43.4 59.0 52.9 13.0 11.3 2.9 12.6 16.7 13.1 12.4 11.5 12.6 14.5 11.3 11.6 12.9 0.6 13.1 11.7 10.9 10.1 12.7 7.4 8.6 8.0 9.7 7.4 7.3 8.9 8.1 9.3 7.7 9.2 9.0 19.1 32.1 29.8 6.5 39.4 17.3 35.9 26.4 34.7 20.5 28.2 24.3 14.5 21.5 24.1 12.9 2.1 63.9 30.6 29.2 25.4 44.5 1.2 23.3 21.8 25.7 28.2 33.4 5.9 49.9 57.2 23.2 26.0 28.5 25.3 35.6 17.9 38.2 38.6 26.9 4.3 31.5 24.4 35.9 20.9 2.4 29.5 22.3 12.4 6.5 29.5 26.8 51.5 2.0 4.8 43.0 33.4 24.0 35.0 52.9 49.3 50.5 12.8 18.1 6.6 28.7 24.9 14.8 20.1 39.5 19.6 72.4 33.3 56.8 43.8 38.0 DDX55 KIAA1595 ENSG00000111364 "DEAD-box helicase 55" Q8NHQ9 12 123602077-123620943 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 74.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039962, HPA044101" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA039962: AB_2676774, HPA044101: AB_2678810" "unprognostic (1.14e-1)" "unprognostic (2.30e-2)" "unprognostic (2.29e-1)" "unprognostic (3.71e-3)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.11e-9)" "unprognostic (1.60e-1)" "unprognostic (4.49e-2)" "unprognostic (7.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-3)" "prognostic unfavorable (8.97e-12)" "unprognostic (9.15e-3)" "unprognostic (2.94e-1)" "unprognostic (3.47e-2)" "unprognostic (1.23e-3)" 11.0 10.3 11.1 10.4 11.1 20.3 11.1 13.2 19.5 12.1 11.2 9.7 7.6 9.6 7.7 11.1 12.2 5.6 6.9 10.7 11.4 12.3 14.7 8.4 13.8 11.5 10.8 13.1 15.4 6.5 11.3 7.7 11.6 11.4 8.8 12.6 9.5 6.3 6.4 13.6 10.8 7.1 9.9 14.9 9.7 9.6 11.3 10.3 9.1 3.4 10.7 10.7 11.1 12.9 20.5 28.4 21.4 21.7 18.0 14.2 32.2 24.8 9.1 21.6 14.8 32.5 14.6 30.2 19.3 10.9 19.5 24.4 32.8 18.4 25.1 22.8 29.7 40.8 34.0 24.3 13.7 50.7 30.7 12.0 19.2 25.7 29.5 16.7 15.8 23.9 42.3 15.5 15.5 21.1 50.0 68.2 33.3 23.6 27.9 37.1 22.7 19.7 15.2 34.8 25.3 21.0 20.2 25.9 35.0 17.7 46.2 32.4 16.3 18.6 24.5 30.6 31.2 28.4 37.4 54.2 17.7 35.8 32.4 3.4 9.1 7.8 11.4 10.6 12.4 13.9 11.1 12.3 7.7 10.7 14.9 13.9 5.2 13.3 6.4 13.2 9.9 8.6 11.1 11.1 13.2 19.5 10.7 11.4 11.5 10.8 11.6 9.9 11.3 12.9 13.3 22.4 13.9 15.7 14.2 11.0 13.4 13.9 9.6 20.2 9.6 14.9 2.5 8.6 11.7 7.3 22.9 13.8 26.3 5.9 7.9 12.2 45.1 9.0 18.4 12.0 7.2 19.6 13.4 12.0 17.4 12.0 11.2 7.2 25.3 16.4 7.1 9.4 14.3 15.2 16.5 15.9 10.2 7.1 7.4 74.8 17.1 9.0 7.2 12.2 9.9 16.1 15.5 6.6 14.3 13.3 7.6 14.7 13.8 13.3 5.9 6.3 12.3 28.1 6.6 10.5 14.1 21.9 18.6 12.5 16.9 7.7 14.2 14.0 10.2 11.0 DEDD "CASP8IP1, DEDD1, DEFT, FLDED1, KE05" ENSG00000158796 "Death effector domain containing" O75618 1 161120974-161132688 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064486, HPA065101, HPA073628" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli" Cytosol "HPA064486: , HPA065101: , HPA073628: AB_2732230" "unprognostic (2.24e-1)" "unprognostic (2.38e-1)" "unprognostic (4.81e-2)" "unprognostic (5.09e-2)" "unprognostic (4.20e-3)" "unprognostic (5.94e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (2.52e-1)" "unprognostic (8.70e-2)" "unprognostic (7.66e-3)" "unprognostic (2.33e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.98e-7)" "unprognostic (1.53e-1)" "unprognostic (1.34e-1)" "unprognostic (4.06e-2)" "unprognostic (1.43e-2)" 34.4 21.4 20.6 19.4 22.0 29.8 29.0 21.9 20.8 26.1 18.8 30.5 20.8 24.7 14.9 25.8 26.5 21.2 24.3 20.2 20.4 21.6 24.3 28.6 21.2 21.3 20.7 28.0 21.2 18.2 17.9 22.1 20.7 23.0 13.7 23.9 20.7 15.8 56.7 29.2 23.5 21.0 20.7 27.8 22.4 28.0 21.5 22.5 24.2 34.9 18.3 26.8 25.1 22.6 24.7 24.0 27.7 24.3 21.0 22.2 19.1 20.7 29.3 23.5 26.1 16.7 41.5 26.2 20.4 31.2 17.2 22.0 21.2 32.5 15.1 26.3 23.1 24.5 30.2 22.7 37.0 17.3 35.5 26.8 34.2 25.3 40.1 31.2 38.5 35.6 21.3 38.3 27.8 38.8 42.4 18.9 46.5 49.1 24.5 34.1 19.1 35.0 23.8 29.6 29.3 44.2 21.1 55.1 37.0 29.9 33.0 34.8 27.3 25.6 27.2 30.0 30.6 52.2 35.6 46.9 30.6 18.5 18.6 64.0 36.9 52.8 27.8 34.6 23.7 24.0 27.4 27.9 33.3 22.7 30.6 25.1 41.2 27.7 38.0 29.2 38.4 31.4 20.6 22.0 21.9 20.8 20.2 20.4 21.3 20.7 20.7 20.7 21.5 22.6 27.8 25.6 9.3 8.5 16.7 25.2 13.9 11.5 14.2 6.8 10.5 8.0 10.6 18.6 10.1 9.2 6.2 19.6 16.2 12.9 23.5 13.6 42.6 9.5 8.3 22.3 11.3 13.7 4.8 19.3 19.6 13.3 15.8 11.3 16.5 7.7 21.0 10.7 14.8 13.5 5.1 8.1 2.0 19.8 27.2 43.5 11.8 16.2 14.2 4.7 20.9 6.7 8.2 5.0 10.8 15.6 13.2 9.8 24.2 10.2 12.5 13.7 7.4 13.2 6.6 12.0 16.5 23.5 18.4 22.2 24.9 27.0 15.0 5.7 9.7 17.4 DENND10 FAM45A ENSG00000119979 "DENN domain containing 10" Q8TCE6 10 119104086-119137984 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 36.5;Cytotrophoblasts: 53.8;Extravillous trophoblasts: 27.7;Hofbauer cells: 56.0;Syncytiotrophoblasts: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041159 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Centrosome, Cytosol" "HPA041159: AB_10793871" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "unprognostic (1.88e-2)" "unprognostic (2.13e-1)" "unprognostic (3.08e-1)" "unprognostic (3.05e-2)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" "unprognostic (6.68e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.20e-2)" 16.7 14.3 18.7 14.0 20.2 32.4 14.0 18.7 23.6 14.2 17.4 17.9 12.6 13.3 16.7 20.5 11.4 12.7 15.5 18.8 19.2 26.1 31.1 12.6 13.1 19.8 18.9 20.9 9.4 18.0 2.9 15.6 19.8 13.4 14.4 10.6 10.9 10.6 17.6 18.7 15.2 13.2 19.8 14.1 14.2 7.3 19.3 13.1 19.9 11.1 14.6 14.8 9.3 21.7 23.7 24.9 38.6 45.5 75.9 59.1 15.9 32.3 85.9 29.4 30.1 23.7 35.8 16.1 12.8 41.4 33.8 42.2 25.7 28.0 27.0 29.2 24.1 3.8 11.5 32.9 75.4 11.0 10.3 63.7 31.5 20.9 32.6 75.0 36.1 16.8 7.8 22.9 42.0 20.0 17.2 48.5 23.6 22.1 14.6 17.0 40.6 14.3 38.6 25.9 6.9 27.7 21.7 30.2 67.5 36.1 24.9 48.5 36.6 23.3 12.3 28.9 19.4 23.0 10.0 17.7 35.9 54.7 11.2 44.9 26.6 55.6 6.9 31.8 6.6 3.9 10.9 10.0 16.6 3.6 5.7 7.1 40.0 6.1 36.4 5.0 20.4 11.6 18.7 20.2 18.7 23.6 18.8 19.2 19.8 18.9 19.8 19.8 19.3 21.7 9.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 53.8 11.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 27.7 9.0 0.0 0.0 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 45.3 1.7 0.0 0.0 0.0 DENND1C "FAM31C, FLJ22757" ENSG00000205744 "DENN domain containing 1C" Q8IV53 19 6467207-6482557 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.2;intestine: 14.4;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "B-cells: 27.5;dendritic cells: 30.1;granulocytes: 15.9;Hofbauer cells: 14.6;NK-cells: 35.0;T-cells: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 22.5;HEL: 15.1;HMC-1: 44.7;MOLT-4: 14.7;THP-1: 13.8;U-937: 31.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042758, HPA042839" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Centrosome" "HPA042758: AB_10962357, HPA042839: AB_10959898" "unprognostic (5.94e-2)" "unprognostic (1.41e-3)" "unprognostic (4.26e-2)" "unprognostic (1.93e-3)" "unprognostic (1.21e-1)" "unprognostic (1.72e-3)" "unprognostic (3.91e-2)" "prognostic favorable (1.23e-4)" "unprognostic (7.76e-3)" "unprognostic (4.45e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.95e-4)" "prognostic favorable (7.51e-14)" "unprognostic (1.37e-3)" "unprognostic (1.27e-1)" "unprognostic (4.53e-2)" "prognostic favorable (5.62e-4)" 2.2 1.0 1.4 21.4 1.3 21.2 1.0 1.5 1.7 0.9 1.5 3.0 4.9 0.9 0.0 1.9 1.3 2.8 1.1 1.4 1.5 1.6 2.1 5.8 32.1 2.4 1.8 0.3 1.3 0.1 0.8 1.8 2.2 1.6 1.2 0.0 3.0 0.5 0.8 1.4 14.4 1.2 1.8 35.1 5.2 0.4 2.8 20.5 1.7 0.3 14.9 3.0 1.3 2.6 0.2 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.5 0.0 22.5 0.1 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.0 15.1 0.0 1.6 0.0 7.5 44.7 0.0 0.0 0.1 0.0 0.0 0.0 7.4 0.3 9.4 0.1 0.0 14.7 11.5 0.0 0.5 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 13.8 0.1 0.0 0.0 0.0 0.0 0.4 2.0 10.6 0.1 31.3 0.0 18.3 19.9 32.8 40.1 32.4 35.0 23.8 28.6 35.0 19.5 18.7 35.7 32.1 27.8 23.8 35.0 11.2 35.6 37.1 1.4 1.3 1.5 1.7 1.4 1.5 2.4 1.8 2.2 1.8 2.8 2.6 0.3 3.2 3.0 0.0 27.5 0.4 0.1 0.0 1.2 0.0 0.6 0.6 1.3 2.8 0.0 1.8 0.0 0.2 30.1 0.5 1.9 0.4 0.7 1.5 0.2 0.4 0.0 5.7 0.4 0.0 0.2 0.7 1.5 0.3 15.9 0.5 1.1 0.7 14.6 0.0 0.5 0.9 0.0 11.6 9.2 0.6 0.0 13.8 3.6 2.8 10.9 0.0 35.0 0.0 0.5 0.3 0.4 0.0 13.5 0.2 2.9 6.2 1.6 0.0 0.0 0.0 0.3 0.3 1.2 1.6 0.1 0.3 34.5 0.7 1.0 0.1 DENND4A "IRLB, MYCPBP" ENSG00000174485 "DENN domain containing 4A" Q7Z401 15 65658046-65792293 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 59.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 195.4;Oligodendrocyte precursor cells: 176.5;Oligodendrocytes: 180.2;Rod photoreceptor cells: 155.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065343 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA065343: AB_2685476" "unprognostic (1.10e-1)" "unprognostic (8.43e-2)" "unprognostic (4.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (8.88e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" "unprognostic (1.66e-1)" "unprognostic (7.83e-2)" "unprognostic (3.45e-1)" "unprognostic (2.24e-1)" "unprognostic (3.48e-1)" 6.2 9.8 4.0 11.4 6.5 33.8 6.8 29.9 7.5 7.4 11.2 6.6 5.8 8.8 5.1 6.6 7.2 11.2 5.1 5.6 5.1 7.9 16.8 9.5 19.7 3.5 4.7 12.8 15.5 10.1 8.4 8.5 4.7 6.0 6.8 59.3 6.1 5.6 9.2 6.5 6.3 7.4 4.2 12.4 8.9 7.9 3.3 12.7 9.3 7.8 18.2 10.2 4.5 7.6 9.9 9.6 4.9 5.1 14.3 15.9 5.9 10.1 13.9 6.8 9.9 5.5 7.8 52.0 6.8 15.1 8.4 18.1 9.7 9.2 12.0 56.7 11.2 49.4 11.7 10.4 8.3 16.8 16.7 10.6 10.3 9.5 20.0 12.0 18.5 11.4 15.2 31.5 7.9 5.2 8.1 9.1 1.5 30.5 6.9 3.9 17.2 45.1 8.0 19.0 7.7 7.0 9.8 6.9 8.9 5.8 6.7 43.1 19.6 9.3 10.3 16.7 14.2 16.8 20.1 19.3 13.1 36.2 7.8 3.2 2.6 5.2 3.6 1.0 5.5 5.4 3.1 4.6 2.3 6.1 3.2 3.1 1.4 3.5 0.9 0.9 3.3 1.5 4.0 6.5 29.9 7.5 5.6 5.1 3.5 4.7 4.7 4.2 3.3 7.6 22.7 16.0 23.1 126.7 81.5 27.9 29.8 7.9 36.5 73.8 23.9 12.2 12.3 20.0 15.2 9.2 60.5 5.6 47.8 5.8 0.0 10.1 2.4 29.3 22.2 23.7 17.4 83.1 195.4 13.0 6.8 22.4 25.0 46.1 48.8 10.5 21.0 25.9 20.4 111.0 140.3 9.7 0.0 19.0 47.5 3.0 13.1 42.2 24.9 145.2 24.5 26.9 20.6 176.5 180.2 12.0 10.1 12.4 55.1 20.2 6.4 9.8 18.1 155.9 6.6 37.9 15.7 11.3 10.9 18.7 17.0 12.6 56.5 13.2 10.0 17.3 DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 120.9;Oligodendrocyte precursor cells: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" 21.7 11.9 5.9 9.2 7.0 10.6 21.7 14.1 6.3 17.2 8.0 17.4 25.1 17.2 14.3 14.5 16.4 13.8 14.5 5.3 5.6 13.9 15.2 18.0 11.8 5.9 5.7 21.4 12.9 19.0 8.7 19.6 5.7 16.1 19.8 11.8 15.1 13.4 10.6 29.6 22.4 14.6 5.8 12.7 19.8 11.2 7.2 17.7 17.3 12.4 11.2 16.6 16.0 6.6 17.7 17.5 11.7 15.3 26.6 28.5 21.4 10.0 14.9 10.2 13.7 8.4 11.6 7.5 8.3 13.6 11.8 9.4 13.7 9.4 12.0 47.2 7.8 34.4 18.5 10.4 13.4 8.3 18.8 11.7 18.7 9.0 15.5 21.6 20.2 9.9 9.4 8.5 13.1 7.4 13.8 18.8 9.0 24.7 8.5 12.6 6.6 10.9 29.2 34.1 10.9 8.5 8.4 20.1 7.4 11.0 12.1 11.3 18.5 8.9 5.2 10.0 10.5 5.8 14.9 4.0 7.7 7.6 5.2 8.3 1.6 1.9 5.4 0.8 7.0 1.7 4.6 5.5 3.1 2.3 4.3 5.0 0.9 6.4 0.9 3.2 3.8 2.4 5.9 7.0 14.1 6.3 5.3 5.6 5.9 5.7 5.7 5.8 7.2 6.6 28.6 9.6 11.5 85.8 21.3 51.2 16.7 18.0 65.4 20.9 16.0 11.0 12.4 14.3 21.6 16.5 60.5 29.4 22.6 26.6 1.9 9.8 7.7 12.7 15.5 22.9 19.8 9.7 78.6 12.5 13.5 24.0 47.4 20.4 27.1 24.8 51.0 11.5 19.0 23.5 87.2 22.6 24.4 23.9 22.0 5.2 18.6 32.2 21.4 120.9 8.5 13.6 27.8 107.1 69.1 12.1 20.9 20.3 14.1 19.4 26.4 4.9 21.6 16.3 0.0 19.5 16.2 3.3 6.8 30.9 49.3 16.1 28.2 12.0 23.3 23.2 DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;gallbladder: 21.0;lymphoid tissue: 20.7;testis: 12.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Erythroid cells: 23.8;Extravillous trophoblasts: 21.6;Spermatocytes: 37.2;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: AB_10669521, HPA072558: AB_2686534" "unprognostic (1.38e-1)" "unprognostic (1.99e-2)" "prognostic favorable (2.42e-4)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.23e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (3.08e-4)" "prognostic unfavorable (6.93e-5)" "unprognostic (2.13e-2)" "unprognostic (8.14e-2)" "unprognostic (1.47e-3)" "unprognostic (2.44e-2)" "unprognostic (1.11e-16)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (8.62e-2)" 0.3 0.2 0.4 3.9 0.7 11.1 0.9 0.5 0.5 0.6 0.1 4.1 6.0 0.6 0.0 2.5 0.2 21.0 0.1 0.3 0.6 2.9 0.4 0.4 9.1 1.2 0.5 0.2 0.1 0.0 0.0 7.5 1.4 0.2 5.5 0.1 0.5 0.1 0.0 2.1 6.4 0.9 0.6 1.6 1.4 12.6 0.6 20.7 1.2 0.0 9.7 1.0 1.1 1.5 61.0 20.3 60.5 37.2 1.3 1.9 66.2 16.1 10.9 27.7 35.8 34.0 37.5 34.6 38.5 5.0 36.0 19.8 49.2 36.1 36.9 49.5 35.5 43.3 22.7 42.6 1.0 36.7 40.3 1.2 3.7 9.0 12.9 5.4 26.1 36.3 31.4 45.8 24.7 38.0 59.8 31.9 44.7 13.0 32.6 65.4 49.2 29.4 22.8 29.9 33.6 15.4 37.7 13.4 17.7 27.0 24.9 28.8 12.1 11.7 34.2 9.5 41.6 23.0 43.3 68.0 14.7 53.2 33.3 1.5 0.1 0.9 0.2 0.0 0.2 0.4 1.0 0.7 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 3.2 0.4 0.4 0.7 0.5 0.5 0.3 0.6 1.2 0.5 1.4 0.6 0.6 1.5 0.2 0.0 1.8 0.0 1.9 4.7 1.0 1.5 0.0 0.1 0.5 0.8 0.1 18.6 0.3 0.0 0.0 7.4 1.1 3.1 0.0 0.3 1.9 3.3 1.4 0.9 0.0 23.8 5.5 0.2 21.6 1.1 2.6 11.7 3.8 5.2 0.0 0.3 6.4 0.0 1.7 2.3 0.0 1.6 2.9 2.4 0.3 1.9 0.0 4.7 0.1 0.2 0.0 2.0 7.0 0.9 5.8 0.0 15.9 0.7 3.7 1.0 0.1 0.1 6.6 0.3 1.4 37.2 12.7 5.8 2.0 46.9 4.5 0.6 7.9 0.9 DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 29.0;kidney: 19.6;liver: 74.0;testis: 28.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 34.8;Early spermatids: 153.3;Extravillous trophoblasts: 47.0;Proximal enterocytes: 33.2;Spermatocytes: 42.3" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 53.7;RH-30: 40.1;SiHa: 37.3;SK-MEL-30: 34.4;U-2197: 34.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: AB_1847610" "unprognostic (2.34e-1)" "unprognostic (5.57e-2)" "unprognostic (1.27e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (7.26e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (8.99e-2)" "unprognostic (1.89e-2)" "unprognostic (9.30e-2)" "unprognostic (8.09e-3)" "unprognostic (2.64e-1)" "unprognostic (2.94e-2)" 0.6 0.8 2.5 1.9 3.2 1.8 0.9 2.9 3.7 2.8 2.7 4.6 24.6 1.0 2.2 4.4 0.9 4.4 1.1 2.6 2.7 19.6 74.0 0.9 0.7 3.2 2.7 1.6 3.8 2.3 0.8 1.5 3.0 1.9 5.1 0.1 2.0 1.5 4.9 6.0 29.0 1.7 2.8 0.3 3.0 28.2 2.7 2.9 0.5 0.9 1.5 1.2 3.4 4.9 9.4 5.2 7.3 3.3 3.8 3.6 4.9 16.2 5.4 9.8 13.0 13.5 0.9 0.0 3.7 16.2 4.5 9.4 10.8 3.8 11.5 0.0 14.9 2.5 16.1 19.3 3.2 9.1 10.9 4.6 5.7 5.7 4.2 5.3 0.0 0.0 6.2 0.0 53.7 1.0 0.0 14.6 4.8 7.7 0.0 0.0 40.1 0.1 3.2 1.3 1.6 4.2 37.3 6.6 34.4 5.1 1.7 4.7 0.0 6.3 10.4 34.1 10.6 0.0 0.0 0.1 2.3 0.0 31.5 4.1 0.5 6.7 0.2 0.1 0.0 0.0 0.4 0.2 3.2 0.0 1.9 2.1 0.0 2.4 0.0 1.2 0.0 0.4 2.5 3.2 2.9 3.7 2.6 2.7 3.2 2.7 3.0 2.8 2.7 4.9 0.2 0.0 0.0 1.0 0.0 34.8 12.8 4.5 12.5 0.0 0.2 0.6 0.1 1.5 0.9 0.0 0.0 0.5 0.5 6.0 3.9 0.9 153.3 0.2 0.2 0.3 3.5 3.2 0.1 0.6 47.0 1.6 0.0 0.1 2.5 0.1 1.4 22.6 3.1 0.0 0.4 2.4 0.0 0.6 9.5 16.3 1.5 1.7 1.8 3.7 1.2 0.0 0.0 3.5 10.4 0.8 0.6 1.2 0.1 2.4 33.2 18.4 0.9 0.0 0.0 4.5 1.4 42.3 6.5 6.6 7.4 1.5 0.7 0.2 2.4 1.6 DEPTOR "DEP.6, DEPDC6, FLJ12428" ENSG00000155792 "DEP domain containing MTOR interacting protein" Q8TB45 8 119873717-120050918 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.2;tongue: 122.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Glandular and luminal cells: 66.1;Oligodendrocytes: 123.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 20.3" "Lineage enriched" "Detected in many" 11 "dendritic cells: 20.3" "Cell line enhanced" "Detected in many" "Daudi: 105.1;RPMI-8226: 193.2;RPTEC TERT1: 149.3;U-698: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020841, HPA023938, HPA023945, HPA024011" Enhanced Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "Nucleoplasm, Nuclear bodies" "CAB020841: , HPA023938: AB_1847606, HPA023945: AB_1847607, HPA024011: AB_1847608" "unprognostic (3.41e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-2)" "unprognostic (1.15e-2)" "unprognostic (3.19e-1)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-1)" "unprognostic (2.49e-2)" "unprognostic (3.24e-2)" "unprognostic (6.02e-2)" "unprognostic (7.29e-2)" "unprognostic (5.66e-2)" "unprognostic (1.02e-1)" "unprognostic (4.16e-2)" "unprognostic (2.84e-2)" 14.4 52.8 12.0 3.0 16.7 2.0 20.7 12.6 11.9 39.2 3.8 23.3 16.9 16.5 11.1 15.2 27.1 10.8 5.1 9.7 23.2 40.0 16.3 5.3 10.1 15.8 12.5 24.7 11.9 16.9 11.4 4.9 15.3 12.1 9.9 2.0 106.3 15.6 158.2 6.6 14.5 15.5 14.8 9.5 40.0 2.9 16.3 5.1 98.0 122.3 2.9 5.6 7.0 24.2 0.1 3.5 0.3 1.1 21.0 6.2 0.3 0.1 0.3 0.6 0.5 2.4 0.4 105.1 2.3 1.2 0.3 0.3 5.4 0.2 0.4 2.3 2.7 14.2 0.9 0.6 12.8 3.0 23.7 5.5 9.5 0.8 0.6 0.1 0.0 1.8 0.1 16.9 0.3 7.1 0.1 2.5 1.3 45.5 3.7 0.4 4.9 193.2 149.3 4.1 3.2 0.7 1.7 11.0 3.2 2.8 9.6 0.5 0.0 0.4 0.9 21.4 0.5 45.4 11.4 55.2 6.5 3.9 0.6 0.0 0.9 0.0 0.2 1.7 0.8 0.1 0.4 0.7 20.3 0.1 0.8 0.6 0.3 0.4 0.2 1.0 0.4 1.0 12.0 16.7 12.6 11.9 9.7 23.2 15.8 12.5 15.3 14.8 16.3 24.2 23.1 6.4 9.3 4.9 2.9 5.2 15.4 3.8 27.3 2.1 16.5 10.4 2.4 15.7 8.4 25.8 0.0 0.6 0.8 2.7 86.1 5.7 2.2 19.0 9.7 7.5 16.7 12.4 14.5 11.8 4.1 10.0 29.6 66.1 12.0 5.4 2.5 12.7 3.3 0.0 31.0 7.7 0.0 16.0 39.5 2.2 11.8 14.9 14.2 46.9 1.5 1.2 2.1 9.5 123.9 1.1 36.5 3.4 6.4 7.1 21.0 33.6 1.1 0.7 0.0 8.1 5.7 3.6 3.8 16.5 5.5 0.4 1.3 6.0 16.5 21.9 DET1 FLJ10103 ENSG00000140543 "DET1 partner of COP1 E3 ubiquitin ligase" Q7L5Y6 15 88494440-88546681 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: AB_2680541" "unprognostic (9.21e-2)" "unprognostic (1.83e-1)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (3.17e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-2)" "unprognostic (6.64e-2)" "unprognostic (1.84e-1)" "unprognostic (4.01e-2)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (2.82e-3)" "unprognostic (2.62e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (4.67e-2)" 3.7 5.2 2.5 2.0 2.8 1.2 3.6 2.7 2.7 6.0 3.2 4.2 3.5 6.7 5.4 2.2 5.6 3.0 5.6 2.5 2.6 3.2 2.7 2.1 2.9 2.7 2.5 10.3 3.6 3.7 3.7 3.5 2.8 4.1 3.2 5.0 4.1 3.8 9.7 2.6 3.2 5.5 2.4 2.5 3.4 1.5 2.6 5.6 4.1 11.7 3.0 4.5 3.3 3.2 1.7 6.2 8.6 6.0 3.4 6.0 1.1 5.4 6.1 4.5 5.1 1.0 4.8 3.3 4.1 7.3 4.5 2.4 8.7 1.3 3.9 0.2 5.9 6.9 3.1 1.5 6.7 2.5 1.1 5.0 5.9 1.9 6.9 4.4 3.8 2.9 8.5 3.8 6.7 2.6 3.2 2.8 3.6 2.6 1.8 4.2 6.9 3.8 2.4 5.3 3.0 4.9 6.5 2.0 14.9 5.6 2.9 5.2 3.0 5.1 3.7 4.8 5.4 2.3 1.4 2.1 5.4 4.3 4.5 0.0 2.3 1.6 2.2 3.4 1.4 1.8 1.7 1.9 3.7 2.2 2.6 1.9 0.3 1.4 2.3 1.9 2.4 1.3 2.5 2.8 2.7 2.7 2.5 2.6 2.7 2.5 2.8 2.4 2.6 3.2 3.5 3.2 2.7 6.8 3.5 0.6 2.0 3.7 4.6 11.5 4.3 3.8 2.3 1.5 2.1 3.7 10.4 7.2 1.7 2.1 1.9 3.4 1.2 3.4 6.1 2.3 3.0 5.5 5.7 3.9 6.3 4.9 2.0 2.4 0.0 10.6 2.2 2.8 4.4 6.7 6.8 2.7 2.0 1.6 2.2 0.6 4.4 2.5 3.6 3.7 4.7 7.1 2.1 6.0 9.5 3.1 1.0 3.8 1.6 1.5 3.1 2.6 3.1 7.9 0.0 5.6 4.5 8.1 9.9 1.5 1.3 4.1 2.7 8.4 3.3 1.4 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 213.5;Proximal enterocytes: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 18.4;PC-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 15.0 24.7 4.6 1.8 4.6 5.1 11.8 5.5 5.6 6.1 4.1 16.7 37.0 5.6 1.0 8.6 5.1 2.0 11.7 4.7 4.1 7.9 16.5 6.9 1.8 4.5 4.6 4.3 6.5 3.9 6.5 1.5 4.2 6.6 4.2 1.6 7.4 2.4 11.7 6.9 40.6 1.6 4.1 9.3 8.7 14.7 4.4 2.3 7.4 3.5 1.4 6.7 6.4 4.5 5.2 4.9 2.2 4.1 3.5 1.5 2.9 3.4 3.1 2.9 2.0 11.2 3.1 2.1 12.4 1.9 1.6 4.0 1.8 4.3 0.6 3.7 5.1 3.3 4.2 18.4 2.5 1.0 3.4 2.1 3.2 2.0 2.1 2.1 2.3 7.3 2.9 5.2 1.9 3.7 6.8 4.1 1.1 10.9 21.2 7.7 0.9 3.4 2.8 2.5 2.6 4.2 4.7 5.2 2.3 0.8 2.9 3.3 2.0 1.6 5.6 3.6 2.8 2.3 0.6 0.8 1.8 6.3 3.2 0.0 0.4 0.7 0.2 0.3 0.4 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.2 4.6 4.6 5.5 5.6 4.7 4.1 4.5 4.6 4.2 4.1 4.4 4.5 34.0 16.0 19.0 15.7 8.5 8.0 12.5 6.3 4.0 24.6 21.6 16.0 20.8 12.8 8.7 18.4 29.2 11.3 17.6 213.5 1.9 9.4 19.2 12.3 13.7 26.5 23.4 17.7 11.2 11.9 10.3 9.3 48.4 21.3 7.0 23.9 12.5 57.4 18.8 18.5 12.8 93.6 4.1 25.5 11.8 25.8 6.8 22.8 5.4 8.4 9.2 21.3 4.1 17.6 7.0 13.3 113.4 6.8 18.8 8.1 700.1 7.4 5.6 23.6 0.0 11.9 12.3 27.7 17.4 12.3 9.2 16.4 12.3 41.1 108.0 20.7 DGCR8 "C22orf12, DGCRK6, Gy1, pasha" ENSG00000128191 "DGCR8 microprocessor complex subunit" Q8WYQ5 22 20080232-20111877 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 61.3;Rod photoreceptor cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076916, HPA079351" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Cytosol" "HPA076916: , HPA079351: " "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (1.97e-1)" "unprognostic (1.81e-1)" "unprognostic (8.34e-2)" "unprognostic (2.75e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.34e-1)" "unprognostic (5.72e-3)" "unprognostic (2.83e-1)" "unprognostic (1.09e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.02e-2)" "unprognostic (4.20e-1)" "unprognostic (4.68e-2)" "unprognostic (2.26e-2)" 5.2 4.4 5.3 6.1 5.2 7.7 4.8 9.4 5.6 6.8 5.0 7.0 5.0 8.5 3.6 7.1 6.9 4.7 5.2 5.3 4.6 4.7 4.5 5.3 6.3 5.1 5.1 8.4 6.2 6.4 5.2 11.6 5.6 5.5 5.0 6.5 7.2 5.6 14.8 7.5 6.7 6.0 4.7 5.9 6.1 15.2 5.3 9.5 6.0 9.3 5.9 6.8 5.7 6.2 22.7 15.7 20.1 11.9 7.7 12.4 25.5 21.3 12.6 14.1 9.9 17.0 11.3 20.1 11.6 20.0 9.4 21.4 18.4 17.8 12.2 19.7 27.4 21.7 17.4 14.0 20.3 40.7 17.5 10.0 21.6 14.8 10.7 12.9 12.6 12.1 78.7 14.1 16.5 14.6 24.7 12.1 19.4 16.5 11.8 29.0 21.2 6.8 8.5 20.9 22.3 14.3 19.4 11.3 13.0 12.0 10.9 17.2 18.8 20.5 17.1 13.0 21.9 7.8 11.5 19.9 15.3 18.2 20.3 0.0 1.1 0.6 2.0 0.9 1.5 0.7 0.9 2.1 1.3 0.6 0.9 1.2 0.2 1.6 3.6 1.5 1.2 1.5 5.3 5.2 9.4 5.6 5.3 4.6 5.1 5.1 5.6 4.7 5.3 6.2 8.1 6.4 7.9 11.8 6.0 9.6 5.2 6.8 10.2 37.1 9.1 8.0 4.2 11.5 7.3 5.5 39.6 13.6 6.9 9.6 0.0 6.1 61.3 5.5 8.3 10.2 7.3 10.3 12.4 10.2 11.2 7.3 12.8 7.3 3.8 19.2 9.7 14.4 5.3 43.7 12.7 10.3 4.1 8.4 6.5 39.2 18.3 5.0 5.4 6.5 7.2 10.9 11.3 9.5 14.0 10.9 5.8 10.5 9.3 8.6 6.2 3.4 8.1 60.7 6.6 9.7 8.1 25.2 17.5 10.4 9.2 13.5 9.3 15.1 9.7 5.6 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 101.5;lymphoid tissue: 198.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 49.0;Squamous epithelial cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 86.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 130.4;hTERT-HME1: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 58: T-cells - T-cell receptor" Vesicles "Nucleoplasm, Mitochondria" "HPA041645: AB_2677595, HPA045462: AB_2679335" "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 12.7 12.8 7.6 50.0 9.8 31.9 11.0 6.6 9.2 22.9 7.0 25.6 51.2 13.1 9.9 101.5 11.4 15.8 8.5 7.2 5.2 7.9 3.7 18.6 95.5 5.2 5.0 10.9 14.6 12.0 6.9 14.9 5.3 24.8 26.9 2.8 35.5 9.6 2.3 84.7 64.8 14.1 4.8 53.8 12.4 12.3 5.0 198.1 10.5 4.2 101.8 28.4 39.0 6.8 22.2 13.2 9.3 12.4 22.4 29.0 2.8 47.2 47.8 18.2 13.5 6.9 35.2 13.5 11.1 31.5 6.2 38.7 10.3 130.4 21.4 14.4 2.5 21.1 26.8 3.6 19.1 6.7 20.9 25.1 68.4 25.2 133.9 60.6 37.9 78.8 2.4 18.7 49.4 2.3 54.3 8.6 2.0 18.1 15.5 23.8 2.9 2.0 43.7 60.9 1.6 5.6 15.5 0.9 1.7 23.8 9.3 6.4 34.0 12.0 8.4 2.8 1.7 2.9 1.2 32.4 13.8 17.5 3.4 17.0 7.4 15.3 18.5 5.2 35.5 20.4 70.6 33.0 10.5 16.2 86.9 51.5 13.3 14.1 3.5 10.5 86.7 36.2 7.6 9.8 6.6 9.2 7.2 5.2 5.2 5.0 5.3 4.8 5.0 6.8 4.5 3.2 6.5 1.6 25.7 15.0 9.7 21.1 26.7 1.2 4.0 4.6 2.9 4.3 19.1 5.5 0.0 16.3 12.2 35.4 0.0 5.1 9.4 1.9 6.5 5.3 2.4 11.2 11.2 9.4 4.3 8.2 15.3 3.0 7.0 2.4 4.2 0.2 4.2 0.0 5.2 7.7 2.0 6.9 21.6 7.0 3.7 14.0 0.0 5.6 15.7 2.6 10.3 9.0 0.8 25.3 14.4 3.0 14.8 8.2 49.0 0.3 5.2 0.5 6.6 1.5 4.2 6.6 4.2 40.4 13.9 26.4 37.4 1.6 9.7 20.1 DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 105.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" 7.4 4.8 3.1 4.2 3.6 3.9 5.8 3.7 3.7 4.0 3.7 5.4 3.9 5.4 2.8 4.2 6.1 2.3 13.8 2.9 2.5 8.0 105.9 3.9 4.2 3.4 3.3 4.9 4.2 6.2 2.5 2.7 3.3 4.0 5.8 3.2 5.4 4.5 10.0 4.5 3.1 5.7 2.1 4.1 4.1 3.6 3.4 3.9 4.1 8.1 5.5 3.9 3.4 5.2 12.5 25.7 6.9 12.1 3.8 5.0 13.9 10.5 4.2 15.6 11.6 20.4 11.1 27.8 13.6 5.7 8.6 12.5 13.7 11.4 18.2 6.0 13.3 15.4 12.6 20.3 10.6 21.4 10.8 4.9 11.3 18.6 19.7 4.7 11.3 18.3 23.9 4.4 9.7 32.7 20.2 17.0 15.9 21.1 10.0 24.9 9.6 29.4 9.4 7.8 8.5 10.2 14.1 14.8 6.8 8.7 13.0 10.3 5.1 14.1 8.3 13.1 15.2 8.8 18.7 46.3 7.1 22.4 12.8 6.1 8.4 1.0 9.4 8.8 12.9 12.0 8.5 9.3 14.5 11.7 11.7 12.6 2.1 10.1 6.3 13.5 8.0 7.2 3.1 3.6 3.7 3.7 2.9 2.5 3.4 3.3 3.3 2.1 3.4 5.2 6.3 3.2 13.1 1.6 7.1 5.6 7.8 11.2 6.8 5.6 6.6 7.1 14.8 15.7 5.5 7.3 4.2 12.3 6.9 1.6 5.9 10.3 2.9 3.8 6.3 9.1 1.2 7.8 2.0 5.1 12.4 7.4 2.6 3.2 8.2 10.2 5.3 124.1 7.9 3.3 2.3 6.6 10.2 6.0 3.1 3.6 2.8 3.3 12.4 1.0 3.8 5.2 8.2 4.0 4.4 5.9 2.4 2.2 4.6 11.2 1.0 20.8 8.1 5.2 0.0 9.7 9.1 6.8 8.1 5.0 3.8 2.9 4.3 13.5 6.7 4.2 DHRS1 "FLJ25430, MGC20204, SDR19C1" ENSG00000157379 "Dehydrogenase/reductase 1" Q96LJ7 14 24290598-24299780 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 68.9;liver: 61.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 178.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000599, HPA076886" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Centrosome, Cytosol" "HPA000599: AB_1078655, HPA076886: " "unprognostic (2.08e-3)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (2.75e-1)" "unprognostic (3.57e-1)" "unprognostic (6.57e-2)" "prognostic favorable (1.18e-5)" "prognostic favorable (6.83e-4)" "unprognostic (3.66e-1)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (9.88e-2)" "unprognostic (2.25e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" 12.4 14.8 2.0 2.8 2.1 4.4 13.3 2.3 2.8 17.6 2.7 16.3 21.5 11.5 5.8 68.9 9.4 5.3 5.4 2.0 2.4 15.0 61.2 9.7 4.4 2.4 2.1 7.0 7.7 13.5 8.8 3.5 2.3 10.1 6.6 1.2 26.2 7.4 2.9 40.7 19.8 5.7 2.3 10.5 11.4 5.5 2.1 4.8 11.7 2.8 9.5 8.9 25.4 2.7 16.6 4.0 4.2 1.7 9.4 10.0 1.1 5.9 12.7 13.4 14.6 1.7 15.7 7.7 2.5 9.3 2.2 14.0 3.2 26.5 6.6 5.4 3.6 2.4 9.1 27.2 4.5 4.8 1.9 8.9 15.9 3.4 2.5 11.2 10.2 6.5 4.9 7.4 11.4 7.0 1.8 1.8 0.7 13.4 6.1 6.0 3.0 10.8 10.5 6.4 3.8 2.7 8.2 11.1 3.0 3.0 5.8 1.4 4.0 1.1 2.6 1.7 2.0 4.1 3.5 3.8 4.9 4.1 1.3 15.1 9.0 18.4 6.5 10.2 7.2 9.9 7.2 6.2 11.1 6.3 7.0 4.0 5.9 5.0 6.2 6.8 12.3 5.2 2.0 2.1 2.3 2.8 2.0 2.4 2.4 2.1 2.3 2.3 2.1 2.7 17.8 22.4 17.1 8.5 18.4 32.9 26.9 89.9 28.5 12.3 32.4 27.3 19.0 50.1 36.1 35.0 18.8 48.3 26.2 59.6 39.2 27.1 21.7 14.2 6.7 17.1 19.2 16.2 6.9 30.4 9.5 16.5 19.4 18.0 6.3 14.6 14.6 105.4 28.1 15.2 9.2 39.8 40.7 14.6 18.0 34.8 20.2 17.0 46.2 4.7 15.2 16.5 24.7 7.1 14.2 64.1 50.3 20.7 21.8 17.9 178.8 74.8 22.6 47.7 26.3 10.4 16.3 27.3 14.0 80.5 45.7 26.1 23.4 13.7 41.3 35.9 DHRS12 "FLJ13639, SDR40C1" ENSG00000102796 "Dehydrogenase/reductase 12" A0PJE2 13 51767993-51804162 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 66.8" "Cell type enhanced" "Detected in many" "Late spermatids: 69.1;Proximal tubular cells: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB034238, HPA057028, HPA058315" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Vesicles" "CAB034238: AB_2091845, HPA057028: AB_2683314, HPA058315: AB_2683678" "prognostic favorable (1.41e-4)" "unprognostic (1.98e-2)" "unprognostic (2.98e-1)" "unprognostic (7.57e-2)" "unprognostic (2.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.47e-3)" "unprognostic (1.70e-1)" "unprognostic (3.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.21e-2)" "unprognostic (3.98e-1)" "prognostic favorable (2.22e-16)" "unprognostic (2.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.03e-2)" "unprognostic (3.44e-1)" 22.7 10.6 7.8 2.9 7.3 4.5 20.5 8.9 7.8 13.9 6.5 14.0 5.5 13.1 5.0 10.3 14.5 6.1 14.3 7.3 6.7 24.6 28.9 11.7 5.3 7.2 6.6 18.4 66.8 6.6 18.7 3.6 7.0 15.4 3.7 5.9 15.0 5.9 16.0 14.1 12.5 4.0 7.6 15.7 15.0 8.2 7.0 2.3 18.8 4.1 3.5 13.2 11.2 8.3 1.1 2.5 3.8 5.6 1.2 2.6 4.4 1.6 4.1 1.8 1.3 4.5 8.6 4.2 1.2 2.5 2.5 2.0 0.0 0.3 0.3 4.2 3.4 0.6 1.1 3.2 6.6 0.4 0.7 2.7 3.9 0.6 2.4 4.5 5.2 4.0 2.0 3.0 1.3 5.5 1.0 3.5 6.1 4.2 0.6 0.5 0.8 5.8 5.6 3.2 3.4 6.9 2.9 2.5 7.1 5.0 2.8 2.8 3.7 1.3 1.5 0.1 1.7 1.4 1.8 1.9 2.3 1.4 3.7 6.6 16.6 0.5 14.0 14.2 24.1 13.7 19.7 16.9 9.0 13.4 16.4 12.9 31.4 3.8 16.5 10.6 19.8 13.5 7.8 7.3 8.9 7.8 7.3 6.7 7.2 6.6 7.0 7.6 7.0 8.3 14.1 12.8 14.8 11.1 11.4 11.3 12.1 22.2 10.8 11.9 23.5 22.9 15.7 18.6 13.3 16.5 8.4 24.9 8.0 7.8 52.8 12.5 26.1 5.6 7.7 10.1 10.3 2.1 4.9 16.7 17.5 17.1 7.1 6.4 12.0 6.8 8.6 30.7 17.1 3.3 5.4 12.4 22.4 11.2 11.6 69.1 11.1 10.1 14.2 3.7 10.5 32.4 8.2 24.6 12.9 12.6 21.9 9.8 4.8 12.2 25.5 83.5 19.5 18.5 0.0 14.2 11.4 1.4 8.2 10.5 14.9 23.8 13.7 13.4 11.0 12.2 DHRS7B "CGI-93, DKFZp566O084, MGC8916, SDR32C1" ENSG00000109016 "Dehydrogenase/reductase 7B" Q6IAN0 17 21123364-21193265 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012132, HPA016873" Uncertain Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cell Junctions, Cytosol" "HPA012132: AB_1847658, HPA016873: AB_1847657" "unprognostic (1.90e-1)" "unprognostic (3.16e-2)" "unprognostic (2.71e-1)" "prognostic favorable (1.98e-8)" "unprognostic (9.83e-2)" "unprognostic (1.18e-1)" "unprognostic (3.46e-1)" "unprognostic (1.45e-1)" "unprognostic (5.02e-3)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.81e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.20e-2)" "unprognostic (6.26e-2)" "unprognostic (9.20e-2)" "unprognostic (3.97e-1)" 19.0 18.8 18.5 8.1 18.6 2.9 19.2 19.6 28.3 17.8 19.9 15.1 15.6 11.4 25.7 12.8 15.9 11.9 22.2 18.6 19.2 22.8 20.2 13.4 7.7 19.3 19.2 8.4 20.2 32.9 7.9 13.2 19.4 15.1 15.8 10.8 18.3 10.2 30.8 18.7 14.5 9.6 19.3 9.2 18.1 24.0 18.3 6.8 16.6 19.5 9.0 12.4 11.1 20.7 17.2 19.9 7.1 15.6 18.5 12.7 12.4 16.0 8.9 11.4 20.7 25.2 17.6 7.2 23.8 13.7 9.0 23.7 10.6 26.2 16.1 13.8 33.9 9.9 13.8 21.8 10.2 5.5 7.0 10.0 17.0 14.6 22.1 5.6 11.3 12.5 6.0 8.6 13.5 35.2 6.0 21.6 9.9 55.4 8.5 10.0 18.8 12.7 39.1 20.5 3.9 8.3 19.8 17.4 17.9 56.8 11.7 11.2 5.6 9.4 6.4 28.7 18.3 4.7 7.9 13.6 14.9 20.3 14.4 19.2 34.3 29.3 6.7 33.9 6.0 7.6 6.5 4.6 21.6 5.9 7.0 6.1 25.0 8.4 40.8 9.4 10.9 14.4 18.5 18.6 19.6 28.3 18.6 19.2 19.3 19.2 19.4 19.3 18.3 20.7 31.1 16.0 18.1 29.4 11.9 16.3 26.7 59.0 11.4 21.3 19.8 17.4 14.1 25.8 38.5 29.5 31.3 52.9 11.3 25.9 17.6 47.2 69.5 38.1 13.6 23.7 7.2 21.9 32.9 39.0 31.8 18.9 14.3 22.2 8.8 13.8 27.5 20.5 29.4 18.5 37.3 28.5 48.8 17.9 15.5 24.4 22.4 14.3 19.6 14.0 20.8 27.6 22.6 36.7 36.2 30.0 24.8 35.0 10.5 29.0 44.4 25.2 50.7 40.1 6.6 15.1 18.2 71.5 22.3 10.7 18.6 51.6 11.2 27.3 22.2 25.1 DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.5;Inhibitory neurons: 21.5;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: AB_2682491, HPA062700: AB_2684838" "unprognostic (8.31e-2)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.29e-2)" "unprognostic (8.38e-2)" "prognostic unfavorable (5.63e-6)" "unprognostic (9.83e-2)" "unprognostic (2.21e-1)" "unprognostic (6.22e-2)" "unprognostic (4.47e-2)" "unprognostic (5.67e-2)" "unprognostic (8.57e-2)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" 6.6 4.2 4.2 4.5 4.9 9.8 6.0 4.4 5.2 10.1 3.1 16.7 6.2 11.2 8.0 8.1 8.5 5.6 10.2 4.5 3.9 6.0 4.8 5.3 6.7 4.1 4.3 7.9 3.7 7.0 3.8 5.2 4.1 8.1 8.6 6.0 5.1 7.2 8.2 6.9 7.9 8.1 3.8 4.8 8.0 6.6 4.2 6.4 5.1 6.3 5.4 11.9 7.0 5.1 10.3 8.4 15.9 6.6 6.0 7.8 11.3 6.0 10.3 13.5 9.9 29.1 9.0 11.4 10.4 11.4 10.4 16.0 11.0 17.5 13.2 2.9 5.2 15.4 14.3 16.7 7.2 18.4 7.7 9.0 11.3 11.7 10.9 8.3 6.1 19.4 16.0 6.5 7.2 8.2 30.0 14.0 9.1 18.5 13.5 14.5 23.2 9.5 5.0 11.8 13.9 11.1 16.4 9.6 15.4 9.9 13.3 14.7 6.0 19.1 10.6 7.8 12.6 6.5 9.2 12.3 10.9 8.2 10.4 0.0 3.0 1.2 2.9 2.7 2.9 2.5 2.4 3.1 4.0 2.9 4.5 2.4 0.6 3.9 2.4 1.4 1.7 2.9 4.2 4.9 4.4 5.2 4.5 3.9 4.1 4.3 4.1 3.8 4.2 5.1 5.4 0.0 3.7 16.0 3.8 0.5 1.4 2.2 7.4 5.1 2.3 3.0 6.7 4.3 4.8 1.8 4.2 3.7 4.1 4.2 1.9 2.4 3.7 2.5 6.6 3.8 5.4 5.5 23.5 1.1 2.4 3.8 7.7 3.2 8.2 6.1 5.7 7.0 5.0 5.0 21.5 6.3 4.1 4.7 4.0 0.8 6.2 3.3 3.6 14.0 3.6 3.3 6.2 22.6 24.8 2.0 5.8 6.4 4.9 2.7 4.6 2.2 4.3 4.7 0.0 4.7 3.9 1.9 9.4 4.5 2.0 3.0 4.5 4.9 5.4 1.1 DHX36 "DDX36, KIAA1488, MLEL1, RHAU" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324487 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 547.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035398, HPA035399" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Mitochondria, Cytosol" "HPA035398: , HPA035399: AB_10670115" "unprognostic (8.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (3.50e-3)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (8.80e-3)" "unprognostic (1.03e-1)" "unprognostic (7.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (2.72e-1)" "unprognostic (5.09e-2)" "unprognostic (5.27e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" 17.7 14.4 5.6 17.3 8.6 16.3 16.4 8.9 7.3 13.9 6.3 12.0 12.6 18.3 11.6 14.8 14.4 15.5 16.9 5.6 8.1 18.6 20.0 13.7 21.7 7.0 7.5 19.0 16.0 29.1 14.9 19.0 7.2 17.3 13.7 17.0 11.7 16.4 58.9 12.0 12.8 17.1 6.9 15.2 16.0 34.4 6.9 21.7 23.1 31.6 20.5 17.2 11.0 10.0 63.8 42.6 56.6 32.7 26.1 36.3 28.1 40.6 40.5 45.2 53.5 43.7 49.7 61.3 64.0 35.8 41.7 40.1 53.8 34.4 70.6 59.3 35.6 44.5 34.8 25.0 44.2 62.7 37.4 41.3 28.5 48.6 59.1 24.5 39.4 37.3 42.6 34.3 42.2 31.0 52.2 13.7 75.4 33.6 40.5 53.4 47.6 88.8 32.1 44.4 52.7 56.1 42.3 44.4 59.7 38.3 45.5 31.5 44.9 47.1 29.6 44.6 82.1 63.6 43.9 87.5 38.1 32.2 51.1 1.2 1.5 1.8 3.7 1.5 2.3 2.6 3.2 2.5 1.3 3.1 2.9 3.1 0.6 2.6 3.5 3.3 3.1 0.6 5.6 8.6 8.9 7.3 5.6 8.1 7.0 7.5 7.2 6.9 6.9 10.0 95.6 57.7 92.9 45.4 123.6 92.9 146.6 56.6 81.4 152.2 61.8 62.6 60.8 67.2 83.5 60.7 129.3 138.0 179.3 43.8 39.2 71.2 547.0 73.4 147.9 82.0 92.0 68.5 53.5 62.8 69.9 97.6 66.8 104.2 103.8 86.7 72.8 80.5 62.0 154.8 60.2 57.4 73.2 73.7 85.2 335.5 110.6 83.0 53.4 37.5 88.5 86.4 113.3 59.3 55.4 66.5 49.9 121.5 97.6 132.2 40.4 54.4 52.3 128.6 78.9 130.6 88.8 197.4 135.1 65.3 83.1 370.1 152.0 114.2 58.1 128.4 DHX57 DDX57 ENSG00000163214 "DExH-box helicase 57" Q6P158 2 38797729-38875934 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 136.3;Late spermatids: 352.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036160 Uncertain Approved "Nucleoli,Intermediate filaments,Microtubules,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments, Microtubules" "Nucleoli, Cytosol" "HPA036160: AB_10670711" "unprognostic (6.78e-2)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (2.03e-3)" "unprognostic (3.25e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.75e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (3.88e-2)" "unprognostic (7.03e-3)" "unprognostic (1.77e-1)" 6.1 9.2 6.6 5.2 6.9 4.8 6.5 6.4 8.8 8.1 6.9 7.1 2.2 7.7 10.3 5.4 6.6 4.2 5.3 7.1 7.2 6.8 5.3 4.9 6.2 5.8 6.5 7.8 7.0 9.7 10.0 5.8 6.0 6.2 5.5 8.5 5.6 6.3 9.1 7.1 5.2 7.3 6.0 5.9 5.7 23.4 6.6 6.7 7.2 5.5 6.3 7.4 6.2 6.5 23.4 19.3 21.0 15.8 13.5 16.6 16.2 15.5 15.9 15.2 14.7 15.7 7.2 7.1 15.6 16.9 17.1 11.8 23.6 18.2 24.9 28.0 18.4 13.3 11.5 21.3 12.2 14.5 7.3 16.0 10.8 20.0 12.5 10.8 20.7 5.2 17.8 9.5 16.7 17.7 14.7 12.9 25.1 10.1 11.4 7.0 27.7 13.9 14.2 8.6 16.8 24.8 15.8 16.4 17.4 14.7 11.7 8.0 15.4 15.1 16.5 10.9 17.7 9.3 12.2 2.8 11.4 10.1 10.2 1.6 6.3 1.2 2.8 4.5 3.6 3.8 2.3 2.1 3.2 4.6 2.9 1.7 0.4 2.3 5.6 1.2 2.5 2.9 6.6 6.9 6.4 8.8 7.1 7.2 5.8 6.5 6.0 6.0 6.6 6.5 6.2 3.2 10.9 24.2 8.8 2.7 2.7 5.9 6.2 24.7 5.2 7.6 6.2 10.0 10.9 23.9 56.3 7.2 4.7 2.5 0.0 7.7 136.3 18.0 13.4 6.3 11.9 8.2 36.7 7.6 6.7 9.3 7.1 6.2 10.8 19.4 9.7 6.2 7.0 18.5 38.0 5.7 4.1 11.7 3.8 352.8 15.8 8.5 1.8 25.3 23.9 9.5 8.2 33.2 20.9 8.5 3.1 13.9 8.1 2.0 2.1 6.0 27.3 27.7 0.0 8.8 6.0 19.3 9.8 5.3 2.6 2.9 7.9 14.7 5.0 2.2 DHX58 "D11LGP2, LGP2" ENSG00000108771 "DExH-box helicase 58" Q96C10 17 42101404-42112714 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 45.5;BJ hTERT+ SV40 Large T+ RasG12V: 52.9;SK-MEL-30: 27.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018670, HPA019570" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Cytosol" Nucleoplasm "HPA018670: AB_1847665, HPA019570: AB_1847666" "prognostic favorable (3.45e-4)" "unprognostic (1.03e-2)" "unprognostic (3.56e-3)" "unprognostic (1.54e-2)" "unprognostic (2.45e-2)" "unprognostic (4.82e-2)" "unprognostic (2.05e-3)" "unprognostic (5.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.15e-1)" "unprognostic (6.02e-2)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (8.65e-2)" "unprognostic (8.01e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 8.9 11.9 5.5 10.2 6.1 12.3 7.6 4.7 7.4 7.7 4.9 7.0 8.5 7.0 5.9 6.4 11.5 12.1 4.9 4.6 4.8 7.3 14.5 11.8 12.5 6.9 5.4 11.9 6.0 7.2 6.9 7.0 6.2 8.7 5.1 0.6 18.6 8.2 3.7 7.5 8.5 7.3 7.5 18.4 9.3 10.8 5.4 12.5 5.5 4.3 7.4 8.0 5.9 6.7 2.5 0.0 0.1 1.3 11.3 9.9 0.3 3.3 22.4 45.5 52.9 0.3 14.6 0.2 3.4 5.4 10.2 2.0 0.2 3.5 1.7 9.3 0.3 3.9 2.6 0.9 12.6 3.6 8.6 15.9 5.9 4.0 3.9 8.0 5.5 23.5 0.0 12.8 2.5 0.0 21.7 4.5 0.4 0.6 0.0 7.8 0.0 1.2 5.2 8.6 0.4 0.0 1.5 5.9 27.0 0.0 7.9 3.8 2.4 2.3 0.1 0.8 1.1 4.3 3.8 0.2 4.6 3.3 2.6 2.3 7.7 6.9 3.1 9.7 4.8 4.6 4.7 2.9 5.9 3.5 5.1 3.8 3.2 6.8 8.6 2.0 4.4 5.0 5.5 6.1 4.7 7.4 4.6 4.8 6.9 5.4 6.2 7.5 5.4 6.7 9.1 9.6 3.4 6.8 4.8 1.5 3.9 6.2 3.4 1.0 3.5 3.7 1.7 8.6 7.6 7.3 0.0 4.0 4.7 2.3 1.9 7.0 9.0 4.5 2.9 7.0 0.0 0.4 1.9 6.9 4.6 4.1 3.6 4.0 1.3 7.5 3.3 14.0 9.8 0.0 2.4 3.2 4.1 7.0 0.7 12.1 8.7 7.4 3.6 8.4 39.9 2.4 2.1 4.0 1.8 5.7 4.3 9.1 1.3 5.4 3.9 5.7 11.6 0.6 0.0 3.7 3.8 18.1 1.0 2.3 1.6 0.8 6.6 8.2 1.9 2.9 DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684663-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.0;Late spermatids: 177.8;Microglial cells: 301.7;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: AB_831223, CAB068183: AB_2665693, CAB068184: AB_2665694, HPA005647: AB_1078657" "unprognostic (5.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.16e-5)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.41e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.12e-4)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (6.44e-2)" "unprognostic (3.11e-2)" "unprognostic (6.99e-3)" "unprognostic (6.08e-3)" 10.7 3.3 3.7 6.4 6.4 17.7 7.0 0.0 4.3 10.6 17.3 8.6 4.3 5.5 3.5 7.7 6.7 5.7 5.4 6.4 3.1 3.1 12.3 8.2 3.8 0.6 0.9 7.7 4.9 7.0 2.0 12.5 1.0 6.1 8.7 3.0 6.6 7.6 12.0 5.3 5.3 7.4 0.2 3.8 7.4 9.4 1.5 6.0 3.9 9.1 3.9 7.4 9.8 1.8 0.0 6.5 3.1 6.3 17.1 28.3 0.0 11.2 11.8 5.9 12.4 5.5 12.3 18.5 8.7 9.7 11.3 0.0 16.6 1.7 7.6 0.5 9.5 0.0 7.4 5.9 14.2 24.3 8.2 14.3 6.0 8.0 24.6 8.0 11.6 13.6 0.0 14.9 11.2 5.3 9.2 10.0 24.4 0.1 9.4 0.0 16.5 0.0 3.4 9.8 0.0 6.3 0.0 3.2 9.0 18.8 2.7 13.2 14.8 12.6 5.8 10.6 7.3 0.2 0.0 15.3 10.7 24.1 7.6 0.0 3.1 3.3 1.1 2.8 0.9 1.7 1.2 1.4 2.3 1.3 0.8 0.7 0.3 0.7 2.5 2.2 0.7 0.6 3.7 6.4 0.0 4.3 6.4 3.1 0.6 0.9 1.0 0.2 1.5 1.8 61.7 32.1 51.1 21.2 18.8 10.8 6.8 11.9 11.4 5.5 9.9 8.1 20.2 15.7 15.0 20.2 0.0 65.2 21.5 36.6 7.9 18.6 80.5 51.2 46.2 31.2 24.6 6.1 171.0 23.4 16.8 35.2 41.8 41.7 7.6 36.1 8.2 26.1 21.0 0.0 90.0 32.3 4.1 29.6 19.3 177.8 45.1 34.7 8.8 301.7 32.7 13.0 10.3 281.0 41.2 38.4 39.3 20.3 11.6 8.0 11.9 9.4 57.1 13.7 26.3 46.7 32.7 7.5 12.9 17.6 18.3 118.3 19.0 19.0 32.5 6.0 DIDO1 "BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333" ENSG00000101191 "Death inducer-obliterator 1" Q9BTC0 20 62877738-62937952 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004374, HPA049904" Supported Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Vesicles, Cytosol" "CAB004374: AB_2093108, HPA049904: AB_2680944" "unprognostic (9.56e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-1)" "unprognostic (7.47e-2)" "unprognostic (2.68e-1)" "prognostic favorable (5.13e-4)" "unprognostic (9.92e-3)" "unprognostic (4.57e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "prognostic favorable (3.88e-4)" "unprognostic (2.20e-2)" "unprognostic (1.50e-3)" "unprognostic (1.06e-1)" "unprognostic (5.64e-2)" "unprognostic (8.90e-2)" "unprognostic (9.82e-2)" 30.4 20.1 15.7 21.5 17.6 29.1 31.0 22.4 17.8 33.8 23.3 36.3 19.6 38.2 26.8 27.1 36.8 17.5 27.6 15.4 17.2 25.5 24.7 30.9 31.6 16.4 16.4 39.5 24.6 28.5 28.1 24.8 16.6 34.0 19.7 19.9 33.2 24.9 32.5 39.5 36.5 20.9 14.0 35.9 28.8 27.9 17.3 30.8 33.0 22.8 26.9 32.6 31.5 22.2 29.6 22.5 36.7 21.0 18.4 22.6 19.6 21.9 18.5 79.4 22.8 96.4 29.9 29.0 29.4 26.9 46.1 45.2 33.8 42.4 51.1 16.1 22.9 41.9 40.2 69.6 23.5 37.8 41.6 23.3 57.0 27.5 15.4 18.1 22.1 54.6 41.7 25.8 20.5 28.7 76.9 33.1 29.4 35.7 32.2 53.7 47.0 18.5 13.1 26.0 45.2 26.7 43.8 41.9 28.9 21.9 41.8 42.7 27.8 64.3 44.8 21.7 31.5 17.1 11.9 38.2 29.3 18.8 23.7 32.6 7.2 20.2 15.0 9.5 15.9 11.7 13.4 14.8 5.1 9.8 17.6 16.5 10.6 13.8 7.6 10.7 11.8 9.6 15.7 17.6 22.4 17.8 15.4 17.2 16.4 16.4 16.6 14.0 17.3 22.2 24.8 25.6 30.1 37.9 28.4 24.2 35.3 17.8 25.6 25.6 23.1 19.6 27.5 22.8 23.8 25.8 33.3 28.6 49.0 32.3 23.5 18.0 42.8 32.1 26.1 26.2 19.2 21.0 44.9 13.8 15.7 24.2 30.1 34.3 22.8 33.8 20.7 19.6 14.5 38.7 46.0 23.2 14.2 16.8 13.7 13.0 35.1 20.2 21.4 32.8 26.8 16.7 42.2 40.7 47.4 22.2 20.2 33.8 30.0 26.3 25.3 9.6 45.8 23.4 6.6 35.4 23.4 26.1 32.1 26.0 25.6 19.7 32.1 25.6 21.1 34.4 DIMT1 "DIMT1L, HSA9761" ENSG00000086189 "DIMT1 rRNA methyltransferase and ribosome maturation factor" Q9UNQ2 5 62347284-62403943 "Enzymes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042944 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA042944: AB_2678234" "unprognostic (1.58e-1)" "unprognostic (2.27e-1)" "unprognostic (6.02e-3)" "unprognostic (7.16e-2)" "unprognostic (8.95e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (8.88e-2)" "unprognostic (1.18e-2)" "unprognostic (1.62e-1)" "unprognostic (5.31e-2)" "unprognostic (3.70e-1)" "prognostic unfavorable (8.90e-12)" "unprognostic (8.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (5.15e-2)" 16.3 13.6 6.5 13.3 6.5 9.1 19.7 6.7 9.6 17.2 6.4 10.9 8.5 14.6 13.9 17.5 14.5 14.2 17.7 6.6 6.8 10.6 15.4 9.8 15.9 6.7 6.7 15.5 19.3 13.3 10.3 17.3 6.7 15.9 12.0 2.9 15.2 16.2 9.7 8.5 8.8 21.0 6.7 13.3 8.5 8.2 6.6 15.0 13.4 12.8 16.8 26.0 11.4 6.7 33.1 19.9 24.2 44.1 37.7 57.4 35.0 57.3 33.7 57.3 55.8 45.1 36.3 61.4 48.4 61.9 45.4 20.2 38.7 35.8 61.3 46.4 34.0 27.2 15.0 33.8 48.1 32.4 34.7 46.7 31.1 54.1 57.3 28.1 46.1 37.0 49.3 27.9 47.3 43.5 50.1 58.6 36.1 18.9 49.7 28.2 33.3 119.2 45.8 29.9 31.5 19.8 38.5 32.2 35.5 19.6 27.0 29.2 40.3 21.0 29.5 33.7 71.2 27.4 46.7 62.6 27.0 61.6 45.1 7.9 5.3 2.7 6.7 9.1 12.7 10.4 11.2 9.1 9.3 6.1 11.6 9.7 0.1 7.7 6.8 12.1 7.8 6.3 6.5 6.5 6.7 9.6 6.6 6.8 6.7 6.7 6.7 6.7 6.6 6.7 25.3 3.2 9.5 6.5 37.8 50.9 90.3 54.8 69.4 6.2 29.9 20.2 35.3 17.2 36.3 14.7 10.4 45.3 21.9 5.0 21.5 28.6 10.1 23.8 28.3 32.0 4.8 20.4 11.1 22.5 48.1 35.6 13.7 23.2 13.3 13.3 17.5 13.4 33.1 0.0 10.5 12.1 32.6 16.4 22.8 4.4 28.9 18.5 28.4 2.8 19.7 7.4 13.4 8.0 12.9 19.8 7.5 20.3 29.3 104.3 4.0 32.5 24.0 4.7 6.6 51.8 49.8 16.5 20.4 58.7 37.8 35.7 31.1 28.6 18.3 76.6 DIO2 "SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 163.9;thyroid gland: 355.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 150.7;Endometrial stromal cells: 158.3;Extravillous trophoblasts: 523.3;Muller glia cells: 246.4" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 80.8;fHDF/TERT166: 41.8;HeLa: 95.4;HHSteC: 44.2;SiHa: 168.1;SK-BR-3: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: AB_2680230" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.67e-4)" "prognostic favorable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" 1.5 3.0 18.0 0.6 15.3 0.1 15.3 15.0 24.6 163.9 5.9 1.3 1.3 40.2 0.5 58.9 0.7 5.1 11.9 17.1 13.0 5.0 0.1 1.6 0.8 13.6 19.2 0.2 1.8 6.6 31.6 14.5 17.4 9.0 1.7 7.4 33.3 30.4 6.5 7.1 1.5 4.5 5.5 0.6 5.3 4.7 13.3 1.2 355.8 70.7 33.1 6.0 25.0 16.6 0.2 9.5 0.0 0.0 0.5 1.4 0.3 80.8 16.6 6.2 0.9 0.0 0.3 0.2 0.2 41.8 0.3 1.7 2.9 0.0 6.1 0.0 0.2 0.0 95.4 0.0 44.2 0.0 0.2 5.1 0.0 1.2 0.0 3.9 1.4 0.0 0.0 0.8 0.5 1.9 0.1 0.1 1.7 0.0 0.5 0.8 3.9 0.1 0.0 0.8 0.0 0.2 168.1 35.3 0.3 7.1 0.1 0.0 0.8 0.3 7.0 17.4 20.1 2.8 0.0 0.0 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 15.3 15.0 24.6 17.1 13.0 13.6 19.2 17.4 5.5 13.3 16.6 0.1 0.0 0.5 52.9 0.3 2.9 0.1 0.0 2.2 3.3 150.7 34.4 1.9 0.0 0.0 0.0 0.0 4.8 0.5 0.2 0.0 0.0 29.5 14.2 158.3 2.3 0.0 0.0 1.0 0.0 523.3 24.6 0.0 15.6 0.0 0.1 0.7 0.2 9.2 1.7 1.0 0.5 0.0 1.3 5.7 12.5 3.4 1.3 5.4 4.7 0.0 246.4 0.0 8.5 1.4 1.0 0.0 4.1 0.3 0.3 0.0 0.0 0.0 7.8 0.0 69.1 6.5 9.7 0.7 8.9 3.0 28.2 1.7 0.9 0.1 0.1 DIP2C KIAA0934 ENSG00000151240 "Disco interacting protein 2 homolog C" Q9Y2E4 10 274190-689668 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 125.4;Excitatory neurons: 219.3;Inhibitory neurons: 269.9;Oligodendrocyte precursor cells: 216.2;Oligodendrocytes: 421.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-2197: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030264, HPA059325" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" Vesicles "HPA030264: AB_10600903, HPA059325: AB_2683979" "unprognostic (1.72e-2)" "unprognostic (3.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (8.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.16e-2)" "unprognostic (1.58e-1)" "unprognostic (2.00e-1)" "unprognostic (6.28e-3)" "unprognostic (5.94e-2)" "unprognostic (3.65e-2)" "prognostic favorable (2.46e-6)" "unprognostic (8.52e-2)" "unprognostic (1.22e-1)" "unprognostic (1.09e-3)" "unprognostic (9.10e-3)" 12.7 7.7 13.8 3.7 18.3 0.2 8.3 18.8 19.9 11.0 0.0 22.1 4.5 12.1 5.4 9.1 8.8 8.6 14.1 13.6 10.7 14.7 8.9 4.9 2.4 16.8 14.6 13.3 8.0 8.1 6.2 4.6 17.4 8.4 4.4 9.4 4.2 9.1 34.5 4.8 7.0 12.4 7.2 3.3 7.3 7.2 18.1 2.1 5.3 20.8 1.5 10.5 7.5 32.6 0.7 6.3 11.5 6.1 19.0 20.5 9.5 13.9 8.6 10.5 8.5 1.8 1.9 0.5 3.6 22.5 2.7 0.1 7.1 1.2 6.4 0.3 6.4 0.1 4.5 2.0 9.2 0.0 8.6 16.9 5.5 6.6 0.0 16.4 2.3 0.1 0.0 1.2 8.0 17.4 0.7 0.0 3.0 5.4 2.6 9.9 4.8 2.0 7.5 7.2 5.8 8.2 2.4 5.0 20.1 6.0 6.6 0.0 0.1 11.1 2.9 33.3 4.6 0.8 14.3 7.2 13.9 0.3 6.4 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.2 0.2 0.0 1.0 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.1 13.8 18.3 18.8 19.9 13.6 10.7 16.8 14.6 17.4 7.2 18.1 32.6 12.6 9.6 5.8 125.4 4.0 7.9 5.4 2.2 7.4 18.6 11.8 10.0 30.3 17.2 4.7 3.7 22.9 5.2 0.6 2.2 0.0 8.5 19.0 7.9 18.5 7.8 10.8 0.0 219.3 4.0 5.8 15.4 10.2 8.8 20.3 16.3 10.4 24.2 6.2 1.7 269.9 6.2 2.0 3.5 5.2 6.1 11.5 3.6 23.2 44.0 0.6 19.4 1.0 216.2 421.7 7.7 1.3 19.5 0.9 7.7 10.2 17.0 5.3 20.5 6.6 22.7 17.6 21.7 22.5 4.3 3.8 3.8 2.0 5.6 5.7 8.9 DIPK1B "C9orf136, FAM69B, MGC20262" ENSG00000165716 "Divergent protein kinase domain 1B" Q5VUD6 9 136712572-136724742 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 15 "Adipocytes: 23.1;Cardiomyocytes: 7.3;Endothelial cells: 6.9;Extravillous trophoblasts: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.8" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "EFO-21: 56.4;HEK 293: 58.2;HUVEC TERT2: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054443 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA054443: AB_2682489" "unprognostic (2.78e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (1.77e-5)" "unprognostic (3.82e-1)" "unprognostic (1.37e-1)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (6.80e-2)" "unprognostic (2.10e-2)" "prognostic favorable (9.48e-5)" "unprognostic (2.77e-1)" "unprognostic (6.67e-3)" "unprognostic (4.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.84e-1)" "unprognostic (2.78e-1)" 17.4 4.8 21.7 3.7 20.3 9.1 14.0 25.7 26.8 14.9 18.7 12.3 5.4 16.8 2.1 4.9 16.7 5.5 35.9 20.1 20.0 17.8 11.4 16.4 5.8 23.5 21.1 11.5 14.3 12.8 25.1 18.7 24.2 13.6 0.8 5.9 9.8 3.1 8.9 11.5 7.7 3.0 17.3 8.6 6.8 15.0 24.2 1.7 16.8 3.8 1.3 8.0 7.7 19.4 3.2 11.3 25.3 21.0 0.0 0.0 19.5 2.9 0.0 0.8 0.9 27.7 6.6 9.2 56.4 0.0 7.9 13.5 11.7 0.3 0.2 8.1 58.2 13.5 4.7 5.9 0.2 7.0 9.0 0.2 0.0 0.3 0.1 10.1 65.2 19.7 14.8 4.2 0.0 14.8 10.8 28.3 36.9 12.6 9.7 49.9 1.9 26.2 1.4 3.7 38.5 38.3 1.8 8.2 27.4 8.7 18.3 21.9 33.3 5.6 18.7 5.3 6.8 12.9 3.3 8.9 3.2 6.7 10.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 2.8 0.2 0.1 0.0 0.0 0.0 1.0 0.1 0.3 21.7 20.3 25.7 26.8 20.1 20.0 23.5 21.1 24.2 17.3 24.2 19.4 23.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 6.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DIRAS1 "Di-Ras1, GBTS1, RIG" ENSG00000176490 "DIRAS family GTPase 1" O95057 19 2714567-2721372 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.8;heart muscle: 105.0;tongue: 51.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Distal tubular cells: 31.3;Excitatory neurons: 20.4;Horizontal cells: 89.2;Inhibitory neurons: 25.9" "Cancer enhanced" "Detected in many" "glioma: 17.4;melanoma: 13.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 43.4;REH: 49.2;SH-SY5Y: 27.8;THP-1: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050164 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" Nucleoplasm "HPA050164: " "unprognostic (7.43e-2)" "unprognostic (1.13e-1)" "unprognostic (2.33e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (4.19e-3)" "unprognostic (8.01e-3)" "unprognostic (2.68e-1)" "unprognostic (5.62e-2)" "unprognostic (3.60e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.00e-1)" "unprognostic (1.79e-3)" "unprognostic (5.47e-3)" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (6.91e-4)" 1.8 2.5 10.5 1.2 20.7 0.7 1.9 16.1 84.8 7.0 0.0 1.4 1.2 12.7 2.5 5.4 6.6 0.7 105.0 19.8 16.9 4.8 0.1 0.6 0.6 17.1 17.4 2.7 6.7 17.0 22.4 0.3 14.5 3.3 1.1 11.5 6.7 1.8 2.7 1.9 2.2 7.4 0.0 4.2 3.5 6.0 45.2 0.1 0.5 51.8 0.7 4.0 2.4 34.8 0.1 2.2 7.0 24.1 0.9 3.1 0.1 8.2 2.8 0.4 0.1 1.4 0.4 0.0 1.0 21.9 12.2 0.1 10.1 0.0 0.0 0.0 15.6 0.5 0.8 0.9 1.0 0.0 43.4 1.4 5.1 0.1 0.1 4.6 0.0 0.2 15.0 7.2 2.8 3.6 0.2 0.4 15.2 0.0 3.3 49.2 0.0 11.7 0.0 0.0 3.1 27.8 0.3 1.1 15.6 1.2 1.1 34.2 0.0 5.3 6.6 0.2 2.6 16.4 12.4 8.9 11.8 0.5 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 20.7 16.1 84.8 19.8 16.9 17.1 17.4 14.5 0.0 45.2 34.8 0.0 0.0 0.0 1.6 6.9 1.1 0.8 0.2 2.2 7.9 2.6 2.8 18.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 31.3 1.4 0.4 0.1 2.2 0.3 0.0 1.3 20.4 2.0 0.5 0.9 0.0 0.3 0.0 2.3 0.0 0.0 5.7 89.2 25.9 0.0 0.0 0.0 3.6 1.1 1.2 0.5 3.6 4.7 0.1 4.6 0.0 2.0 3.4 1.5 0.0 0.0 0.6 0.9 0.0 0.1 0.0 6.1 0.0 0.7 2.1 0.7 0.4 0.3 0.4 0.3 0.1 0.0 0.0 0.2 DIS3L "DIS3L1, FLJ38088, KIAA1955, MGC4562" ENSG00000166938 "DIS3 like exosome 3'-5' exoribonuclease" Q8TF46 15 66293217-66333898 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041805 Approved Supported "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Centrosome "HPA041805: AB_10796783" "unprognostic (2.57e-1)" "unprognostic (5.37e-2)" "unprognostic (1.12e-1)" "unprognostic (3.99e-2)" "unprognostic (3.16e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (1.28e-2)" "unprognostic (1.59e-3)" "unprognostic (1.86e-1)" "unprognostic (3.42e-3)" "unprognostic (2.66e-1)" "unprognostic (6.18e-2)" "unprognostic (9.58e-2)" "unprognostic (3.40e-1)" 11.0 11.8 7.9 6.2 9.8 7.6 9.3 8.9 8.6 10.3 7.7 11.1 5.1 11.1 9.5 7.5 9.6 5.5 12.7 8.0 9.1 8.3 11.0 5.9 7.6 8.7 9.4 11.1 12.8 15.8 10.0 5.4 9.6 8.7 6.0 11.4 8.9 9.0 23.2 7.4 7.7 8.8 8.8 8.7 9.0 9.8 8.9 7.8 11.0 28.3 7.2 9.6 8.1 12.2 14.0 32.6 10.6 14.1 12.2 16.4 12.4 9.5 11.1 14.3 13.2 17.6 10.1 51.6 10.3 13.4 14.9 23.3 25.7 9.2 9.2 12.0 24.1 26.7 25.1 20.1 9.5 27.7 10.1 6.9 9.7 4.5 14.8 9.7 13.1 17.7 18.6 12.6 14.4 12.3 13.8 17.3 15.4 12.7 20.0 18.3 42.1 30.0 5.7 18.9 17.1 15.7 22.3 7.6 11.4 10.0 10.6 21.8 14.4 18.7 16.8 7.4 18.7 10.1 36.9 24.0 6.4 35.9 7.8 8.5 5.1 4.3 7.6 6.1 10.2 6.5 7.7 10.0 8.5 7.8 8.8 7.3 0.6 11.7 13.2 6.7 8.0 6.7 7.9 9.8 8.9 8.6 8.0 9.1 8.7 9.4 9.6 8.8 8.9 12.2 7.1 6.4 16.2 22.5 14.6 4.2 5.5 4.0 17.1 15.6 9.4 7.6 30.3 15.7 7.1 3.7 4.2 17.0 9.6 5.0 5.9 6.5 7.1 8.3 14.6 10.2 3.0 24.2 11.4 3.5 4.5 12.4 10.7 7.3 16.5 25.1 7.1 19.2 9.6 10.1 17.2 10.6 8.2 12.3 7.8 9.9 19.9 10.1 1.8 13.1 14.4 17.7 12.3 22.6 23.1 3.3 5.1 20.3 18.4 4.8 5.4 9.8 8.1 23.2 19.7 9.5 10.1 28.5 17.2 12.1 5.4 3.7 16.0 16.5 14.0 3.8 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 DLGAP3 "DAP3, SAPAP3" ENSG00000116544 "DLG associated protein 3" O95886 1 34865436-34929650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.6" "Cell type enhanced" "Detected in many" "Early spermatids: 18.9;Excitatory neurons: 39.1;Horizontal cells: 21.9;Inhibitory neurons: 27.9;Late spermatids: 19.3" "Cancer enhanced" "Detected in some" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 8.0;NTERA-2: 4.2;SCLC-21H: 12.5;SH-SY5Y: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026445, HPA027304" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "Plasma membrane, Midbody" "HPA026445: AB_1847733, HPA027304: " "unprognostic (8.63e-2)" "unprognostic (8.58e-2)" "unprognostic (1.48e-1)" "unprognostic (5.77e-7)" "unprognostic (4.01e-2)" "unprognostic (5.51e-2)" "unprognostic (2.95e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-4)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (6.12e-2)" "unprognostic (1.47e-1)" "unprognostic (2.26e-1)" "unprognostic (2.21e-1)" 0.3 0.4 46.9 0.5 41.2 1.1 0.2 0.0 48.2 0.2 0.0 0.3 0.2 0.3 0.0 0.1 0.3 0.1 0.1 36.0 19.1 1.3 0.1 0.2 0.3 0.0 17.8 0.1 1.1 0.2 4.8 0.0 0.0 0.2 0.0 1.8 0.2 0.2 0.1 0.2 0.5 0.0 0.0 1.9 0.3 7.5 51.6 0.3 0.4 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 8.0 0.1 0.0 1.0 0.0 1.3 0.0 0.0 0.1 0.1 0.6 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 1.3 0.0 0.0 4.2 0.0 0.0 0.4 0.0 0.1 0.0 0.4 12.5 2.4 0.1 0.1 0.0 0.2 0.3 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.2 46.9 41.2 0.0 48.2 36.0 19.1 0.0 17.8 0.0 0.0 51.6 0.0 0.2 0.0 0.0 1.0 1.8 0.3 0.9 0.8 1.8 4.1 0.7 0.8 1.0 0.0 0.1 1.8 4.2 0.1 0.9 0.8 3.9 0.4 18.9 0.2 0.1 0.4 1.2 0.0 39.1 0.6 0.2 0.4 0.0 0.1 0.0 0.3 0.4 0.1 10.1 21.9 27.9 0.4 0.0 7.1 0.6 19.3 0.9 4.1 0.0 1.9 0.7 1.5 1.0 8.0 0.7 0.2 0.0 0.0 0.8 0.2 1.3 0.8 0.0 2.2 0.0 0.7 0.4 3.4 4.9 1.1 0.3 0.0 1.3 0.1 0.9 0.6 DLK2 "EGFL9, MGC2487" ENSG00000171462 "Delta like non-canonical Notch ligand 2" Q6UY11 6 43450352-43456632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.3;prostate: 12.9;skin 1: 12.7" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 96.9;Basal respiratory cells: 56.8;Basal squamous epithelial cells: 64.3;Breast myoepithelial cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 24.1;HBEC3-KT: 13.1;hTCEpi: 38.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA061223, HPA068672, HPA070955" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Vesicles" "HPA061223: AB_2684454, HPA068672: AB_2686017, HPA070955: " "unprognostic (4.65e-5)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (9.68e-4)" "unprognostic (2.87e-1)" "unprognostic (3.80e-1)" "unprognostic (4.19e-3)" "unprognostic (1.65e-1)" "unprognostic (2.65e-3)" "unprognostic (4.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.88e-1)" "unprognostic (9.27e-12)" "unprognostic (7.71e-4)" "unprognostic (8.92e-2)" "unprognostic (1.55e-1)" "unprognostic (6.43e-2)" 0.8 0.5 3.8 0.7 4.5 0.9 2.9 6.9 7.0 2.9 1.8 0.4 0.4 0.6 2.0 12.3 0.6 0.3 1.7 4.4 4.2 0.5 0.7 0.5 0.9 2.7 2.6 1.1 0.8 0.1 0.8 0.6 2.7 12.9 0.0 0.6 8.1 5.2 0.2 12.7 0.6 0.1 2.6 0.7 0.4 1.0 3.5 2.3 0.7 0.0 0.9 0.8 6.7 3.2 7.9 2.8 0.8 11.3 0.0 0.6 2.5 2.8 3.0 3.1 1.4 2.7 0.4 1.5 1.7 0.5 3.8 24.1 8.0 13.1 0.7 1.5 3.0 0.6 1.5 4.2 0.8 0.5 1.6 1.3 38.5 0.9 7.1 1.0 0.0 4.5 0.7 1.1 1.2 3.0 0.6 0.6 1.0 3.0 2.9 1.6 1.4 0.7 0.4 2.6 8.3 0.8 0.9 0.3 0.4 0.6 0.7 2.4 0.8 1.1 3.6 0.8 5.6 1.8 0.4 2.5 0.1 1.1 0.8 0.3 0.1 0.1 0.1 0.0 0.8 0.1 0.5 0.5 0.0 0.2 0.2 0.1 0.2 0.8 0.1 0.5 0.0 0.1 3.8 4.5 6.9 7.0 4.4 4.2 2.7 2.6 2.7 2.6 3.5 3.2 0.3 0.0 0.5 0.3 0.4 10.1 96.9 56.8 64.3 1.3 0.6 26.7 0.6 0.0 6.0 0.0 0.0 1.3 0.5 0.0 0.0 0.1 0.3 0.1 3.0 0.7 1.2 0.0 6.1 0.0 2.7 0.4 0.0 0.2 0.0 4.7 0.0 0.0 0.1 11.8 2.8 0.0 2.0 0.0 0.4 0.5 0.3 0.6 1.8 2.8 0.0 0.6 0.0 3.0 0.9 0.1 0.0 0.0 0.1 12.9 0.0 0.0 1.1 1.2 0.0 0.5 1.1 1.7 7.0 6.7 2.6 0.3 1.3 0.4 0.0 8.3 DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.7;choroid plexus: 2.3;pituitary gland: 3.4;testis: 1.4" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 24.6;Spermatogonia: 39.5" "Group enriched" "Detected in many" 11 "glioma: 29.2;melanoma: 15.5;testis cancer: 8.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cell line enriched" "Detected in some" 6 "SK-MEL-30: 83.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (2.52e-1)" "unprognostic (3.81e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.65e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.82e-4)" "unprognostic (4.94e-2)" "unprognostic (5.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.97e-1)" 0.0 0.0 5.1 0.1 5.7 0.0 0.0 3.1 5.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.7 0.0 0.0 0.0 0.1 4.9 4.7 0.2 0.0 0.5 3.4 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.1 0.0 1.4 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.1 3.9 0.9 2.0 0.0 0.0 0.6 1.1 0.0 0.7 0.2 0.5 0.9 0.1 3.7 0.0 1.5 0.1 2.3 1.0 0.2 1.2 6.0 0.2 0.1 0.3 0.3 1.0 4.6 0.0 0.0 0.1 0.1 0.1 0.1 4.3 1.1 0.1 0.3 0.0 0.2 0.0 0.7 0.0 6.2 0.6 0.2 0.2 0.2 0.2 13.6 14.1 2.9 0.1 83.7 0.3 0.0 0.2 0.0 0.0 2.6 0.1 1.0 1.4 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.5 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 5.1 5.7 3.1 5.6 4.7 4.7 4.9 4.7 4.2 4.4 4.6 5.4 0.3 0.0 0.0 0.3 1.1 0.3 0.3 0.4 0.0 0.5 1.3 4.7 0.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.7 0.6 0.1 0.7 0.2 3.0 0.0 1.7 0.6 0.6 1.0 0.5 0.3 0.0 1.7 0.0 0.0 0.3 0.0 3.4 0.3 0.0 0.0 0.0 2.2 1.2 0.1 1.8 0.0 0.0 0.9 0.0 24.6 0.5 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.7 6.6 0.0 0.6 6.5 39.5 0.2 0.1 0.3 0.5 1.7 0.0 0.1 DLST "DLTS, KGD2, OGDC-E2" ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903743 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA 70000 "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Mitochondria, Cytosol" "HPA003010: AB_1078679" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "unprognostic (2.45e-3)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.13e-12)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (4.55e-3)" 64.5 85.5 33.5 32.3 34.7 75.0 59.6 35.8 34.7 62.1 43.8 63.3 58.7 47.5 43.2 62.9 46.1 36.2 129.0 30.8 35.1 100.4 78.4 48.5 36.9 35.8 34.5 45.8 44.8 78.8 35.4 44.8 34.3 41.3 59.3 37.1 46.5 43.5 144.7 64.3 58.3 52.1 33.6 46.1 57.7 29.3 37.3 42.5 42.9 224.2 45.7 58.0 49.7 32.5 79.1 81.1 63.7 45.4 98.1 110.6 97.5 106.3 107.8 106.8 99.0 80.9 88.1 81.0 44.3 118.1 48.1 87.8 109.0 105.6 112.0 61.5 43.3 68.4 66.3 74.8 101.4 49.5 45.4 114.0 90.5 103.8 126.7 95.5 106.1 36.6 53.4 55.6 110.3 112.0 59.0 69.7 55.0 146.6 79.0 73.8 93.8 46.7 125.8 100.8 75.5 64.1 100.6 129.4 71.3 54.2 121.7 70.5 90.8 63.8 83.2 79.5 74.0 38.7 43.7 73.4 93.9 47.9 68.8 3.0 1.3 2.3 2.1 2.0 1.8 1.6 1.9 1.6 2.1 1.0 1.5 2.2 1.3 3.5 1.8 2.8 2.0 1.5 33.5 34.7 35.8 34.7 30.8 35.1 35.8 34.5 34.3 33.6 37.3 32.5 24.2 6.4 4.8 14.0 22.7 26.4 23.5 19.7 21.6 19.1 25.1 20.4 28.5 21.5 10.1 20.2 31.3 41.0 27.7 41.9 56.7 37.8 7.3 10.9 20.4 19.8 14.8 22.5 21.9 25.7 38.8 25.6 30.5 18.9 21.0 19.4 23.2 43.6 32.1 13.5 24.6 31.8 12.2 20.9 19.0 6.2 18.0 18.8 23.2 13.1 27.1 10.0 20.6 18.6 18.5 44.3 28.0 20.7 20.0 28.2 49.8 73.3 8.7 20.8 26.3 18.3 24.0 12.1 15.3 34.2 28.4 79.5 23.1 19.3 40.5 27.7 DLX1 ENSG00000144355 "Distal-less homeobox 1" P56177 2 172084740-172089677 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 18.8" "Cell type enriched" "Detected in some" 23 "Inhibitory neurons: 30.4" "Cancer enhanced" "Detected in many" "prostate cancer: 11.1" "Region enhanced" "Detected in many" "hypothalamus: 18.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 134.5;U-138 MG: 36.9;WM-115: 42.1" "Group enriched" "Detected in many" 5 "basal ganglia: 28.6;olfactory bulb: 82.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 48.8" "HPA007175, HPA045884" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA007175: , HPA045884: AB_10960361" "unprognostic (2.14e-2)" "unprognostic (5.09e-2)" "unprognostic (3.92e-2)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (7.92e-3)" "unprognostic (8.86e-2)" "unprognostic (2.80e-2)" "unprognostic (2.03e-1)" "unprognostic (5.74e-2)" "unprognostic (2.04e-1)" "unprognostic (7.40e-9)" "unprognostic (2.22e-1)" "unprognostic (9.19e-2)" "unprognostic (1.25e-1)" "unprognostic (5.91e-3)" 0.1 1.3 5.9 0.2 4.8 0.0 0.1 0.0 4.4 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.5 18.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.1 0.5 0.2 0.1 0.0 0.0 0.1 0.0 3.5 0.0 1.0 0.1 0.3 0.1 0.2 2.7 2.4 0.6 0.6 134.5 2.0 4.5 0.3 3.2 6.5 7.7 4.1 1.0 0.2 0.0 7.8 7.2 7.5 9.4 7.4 1.2 5.2 0.3 33.3 21.1 14.4 5.7 0.1 7.9 15.9 0.0 2.2 1.9 3.2 5.4 0.0 6.7 12.4 0.0 6.3 8.1 0.1 1.9 0.1 0.0 22.9 0.4 15.8 0.0 0.9 4.5 11.3 0.0 6.1 0.8 17.5 0.4 5.2 9.5 7.1 36.9 0.2 16.4 16.4 0.2 0.0 0.1 15.2 21.4 42.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 4.8 0.0 4.4 3.5 18.8 0.0 0.2 0.0 0.0 3.5 2.7 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.2;lymphoid tissue: 20.9;parathyroid gland: 46.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 115.4;Ionocytes: 46.8;Skeletal myocytes: 22.7" "Group enriched" "Detected in many" 4 "lung cancer: 3.0;renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.8;RH-30: 5.0;RPMI-8226: 19.4;SK-MEL-30: 5.2;THP-1: 3.6;WM-115: 3.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: AB_10600905" "unprognostic (5.67e-2)" "unprognostic (2.20e-3)" "unprognostic (3.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-3)" "unprognostic (8.93e-2)" "unprognostic (8.62e-2)" "unprognostic (4.93e-2)" "unprognostic (1.27e-3)" 4.7 0.1 1.7 0.1 3.4 0.0 5.3 3.1 2.7 0.1 0.2 1.6 0.0 0.1 1.1 0.3 0.6 0.0 0.1 1.9 1.9 41.2 0.0 3.1 0.2 3.0 3.1 0.0 0.0 46.4 0.5 0.2 2.9 0.3 0.9 0.4 1.3 1.4 13.3 0.3 0.1 0.0 1.7 0.0 0.0 0.8 2.8 20.9 0.1 2.5 0.1 0.0 0.2 8.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.0 19.4 0.0 0.8 2.9 0.0 0.0 0.0 5.2 0.3 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.4 3.1 2.7 1.9 1.9 3.0 3.1 2.9 1.7 2.8 8.5 0.5 0.0 0.0 0.3 0.2 0.5 0.6 1.8 0.0 0.1 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.1 0.1 1.8 115.4 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.0 46.8 0.0 1.1 0.4 0.6 0.2 3.6 0.0 0.0 0.3 0.0 0.5 11.1 0.0 1.9 0.0 0.4 0.2 0.0 0.4 0.6 2.4 0.0 22.7 0.7 4.0 3.0 0.2 0.1 0.1 0.1 0.0 1.8 0.4 DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.7;testis: 45.3" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Endometrial ciliated cells: 311.3;Plasma cells: 225.4;Respiratory ciliated cells: 494.5;Spermatocytes: 116.2" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Group enriched" "Detected in many" 4 "granulocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;Karpas-707: 4.9;PC-3: 1.4;SK-BR-3: 1.4;U-266/70: 4.0;U-266/84: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041166, HPA074239" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "Nuclear speckles" "HPA041166: AB_10794190, HPA074239: AB_2732250" "unprognostic (5.25e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-2)" "prognostic favorable (2.14e-4)" "unprognostic (1.42e-1)" "unprognostic (9.99e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (7.71e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-5)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-4)" "unprognostic (7.51e-4)" 0.3 0.7 1.4 0.1 1.2 1.2 0.3 1.1 1.9 2.2 9.7 0.3 0.0 0.5 1.4 0.4 22.7 0.0 0.4 1.6 1.5 1.0 0.8 3.5 0.0 4.1 7.3 0.4 0.3 0.3 2.4 0.2 4.3 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 3.0 0.7 0.2 45.3 1.6 0.0 1.6 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 4.0 2.8 0.4 0.1 0.0 0.0 1.3 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.3 0.3 0.1 0.4 1.0 0.3 1.4 1.2 1.1 1.9 1.6 1.5 4.1 7.3 4.3 3.0 1.6 1.3 1.1 0.0 12.4 1.6 5.7 0.6 1.5 9.6 0.0 1.4 4.5 1.5 0.7 1.5 67.2 3.7 54.2 0.2 0.5 0.1 0.0 1.3 116.2 311.3 4.4 1.9 0.0 0.0 9.6 0.4 0.4 2.4 0.5 14.6 3.8 2.6 2.2 0.6 1.9 0.0 5.2 0.0 18.3 7.0 1.5 26.7 1.2 21.6 87.2 0.0 0.8 2.4 1.0 0.5 0.6 0.9 0.0 0.4 225.4 1.4 0.0 1.7 494.5 51.0 0.0 1.6 7.3 116.2 17.0 0.2 0.3 0.4 4.5 1.2 0.3 0.9 DNAH17 "DNAHL1, DNEL2, FLJ40457" ENSG00000187775 "Dynein axonemal heavy chain 17" Q9UFH2 17 78423697-78577396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 2.1;retina: 2.5;testis: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 56.4;Cone photoreceptor cells: 87.6;Early spermatids: 43.7;Late spermatids: 36.6;Oligodendrocytes: 52.5" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.9;lung cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 5.7;MOLT-4: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA024354, HPA076261" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Plasma membrane" Cytosol "HPA024354: AB_1847911, HPA076261: AB_2732305" "unprognostic (4.98e-4)" "unprognostic (2.26e-1)" "unprognostic (2.30e-3)" "unprognostic (8.70e-3)" "unprognostic (6.66e-2)" "unprognostic (9.23e-2)" "unprognostic (3.72e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.20e-3)" "unprognostic (8.35e-3)" "unprognostic (1.58e-10)" "unprognostic (5.25e-2)" "unprognostic (1.54e-1)" "unprognostic (5.12e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 5.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.2 1.6 0.8 1.3 0.9 0.6 2.1 0.4 6.4 0.5 0.7 0.6 0.6 0.3 0.1 0.0 56.4 0.1 0.0 2.5 0.0 0.0 0.0 87.6 0.0 0.1 0.0 0.0 0.0 43.7 1.4 0.5 1.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 1.7 0.0 0.1 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.8 1.7 36.6 0.6 2.9 0.0 1.0 0.1 1.5 0.0 1.0 52.5 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 7.8 0.0 0.6 0.5 17.4 0.6 0.0 0.1 0.0 0.3 0.4 0.0 0.1 DNAJA2 "CPR3, DNAJ, DNJ3, HIRIP4" ENSG00000069345 "DnaJ heat shock protein family (Hsp40) member A2" O60884 16 46955362-46973674 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049789, HPA060538" Approved Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 67000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Cytosol" "Intermediate filaments" "HPA049789: AB_2680883, HPA060538: AB_2684315" "unprognostic (7.68e-3)" "unprognostic (1.05e-2)" "unprognostic (4.77e-2)" "unprognostic (3.67e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.81e-4)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (5.41e-2)" "unprognostic (2.12e-1)" "prognostic favorable (1.19e-9)" "unprognostic (9.22e-2)" "unprognostic (2.28e-1)" "unprognostic (9.22e-2)" "unprognostic (4.69e-2)" 20.7 25.2 30.5 14.2 32.6 23.9 19.7 33.9 40.5 17.9 32.2 21.3 20.0 22.0 28.6 21.5 17.4 16.4 36.0 32.3 31.9 28.0 36.0 16.6 19.7 29.8 30.2 22.0 17.0 29.2 16.4 19.9 30.5 21.8 19.0 29.5 17.1 20.6 37.1 21.1 20.5 17.0 31.0 22.7 19.2 24.9 31.2 20.3 22.2 38.7 21.4 21.6 18.2 30.5 23.1 26.9 26.6 22.8 35.7 34.1 40.3 29.4 35.4 43.4 20.5 23.7 23.6 37.1 23.2 31.9 18.6 35.0 43.0 30.2 49.8 8.8 36.0 27.2 12.8 50.7 42.7 41.7 36.3 36.5 34.6 25.2 23.7 37.9 30.4 14.7 31.7 12.0 37.0 25.4 30.1 57.5 40.6 21.1 39.6 34.3 48.7 44.1 52.7 24.1 36.1 23.1 34.9 52.1 33.4 26.1 20.3 32.2 31.6 25.4 16.0 18.5 25.1 29.3 21.7 49.0 26.9 35.5 21.8 13.1 10.3 13.5 9.8 12.7 12.9 11.3 13.2 11.2 9.4 8.4 12.9 13.1 10.7 12.8 11.3 6.7 17.2 9.7 30.5 32.6 33.9 40.5 32.3 31.9 29.8 30.2 30.5 31.0 31.2 30.5 64.3 51.3 35.9 11.8 78.4 126.9 75.1 56.4 101.3 38.8 37.5 28.4 100.3 40.0 48.2 40.5 18.8 85.2 76.1 67.6 90.1 73.4 93.3 86.9 76.8 52.2 52.0 49.4 16.6 62.2 72.5 66.2 54.0 72.1 53.9 52.7 31.1 54.9 56.5 37.0 15.3 55.6 52.9 42.5 86.4 56.8 50.1 65.1 72.9 12.2 72.3 60.5 45.3 10.1 11.0 71.2 64.2 59.0 70.7 61.6 83.3 111.4 67.6 43.7 52.6 63.4 99.4 177.7 106.0 111.1 120.5 172.4 89.6 131.4 62.6 87.3 DNAJB4 HLJ1 ENSG00000162616 "DnaJ heat shock protein family (Hsp40) member B4" Q9UDY4 1 77979175-78017964 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 119.0;HUVEC TERT2: 182.3;LHCN-M2: 312.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004995, HPA028383, HPA028385" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 9500 "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "CAB004995: AB_425882, HPA028383: AB_10599601, HPA028385: AB_10599944" "unprognostic (1.21e-1)" "unprognostic (4.36e-2)" "unprognostic (2.19e-1)" "unprognostic (5.50e-3)" "unprognostic (3.40e-2)" "unprognostic (4.76e-3)" "unprognostic (4.32e-3)" "unprognostic (3.93e-3)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (2.00e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (7.12e-3)" "unprognostic (1.01e-2)" 31.6 49.7 21.9 11.1 24.2 6.7 15.4 24.4 74.6 24.0 19.9 14.3 6.4 21.3 10.8 26.4 13.9 32.3 50.4 23.1 27.1 20.6 20.0 17.0 9.7 23.0 24.8 16.0 22.8 14.1 11.6 26.0 23.0 23.3 11.2 15.0 7.6 14.1 44.1 9.6 9.6 29.9 23.3 42.2 12.3 7.9 25.9 10.5 44.5 71.4 6.2 23.6 12.8 35.3 6.2 11.8 14.5 8.6 61.8 115.0 6.7 119.0 28.8 50.8 56.8 3.9 8.0 8.9 19.4 55.5 20.7 9.2 18.7 10.1 86.1 10.1 5.3 4.5 32.9 28.7 84.1 2.5 2.4 47.9 27.9 66.5 18.9 28.4 182.3 2.9 19.6 6.1 312.1 0.7 3.0 6.6 9.4 1.8 5.6 5.0 25.2 5.9 12.0 3.1 10.8 3.4 13.3 10.0 11.7 15.0 3.9 3.7 88.7 72.5 17.8 51.2 15.9 5.5 1.8 7.9 9.9 5.3 12.9 3.3 0.7 1.2 1.1 0.8 1.8 1.6 1.3 1.3 0.7 1.3 3.0 2.1 0.2 1.6 0.9 2.3 1.9 0.9 21.9 24.2 24.4 74.6 23.1 27.1 23.0 24.8 23.0 23.3 25.9 35.3 81.5 60.9 6.3 35.9 23.9 41.7 112.5 16.3 48.3 29.3 90.9 57.1 98.7 18.6 20.0 18.4 68.8 51.2 15.3 40.9 37.2 11.2 144.7 55.1 37.3 84.4 21.4 42.1 41.6 14.7 23.2 87.3 45.9 51.9 56.6 16.7 42.8 22.3 19.4 30.3 39.0 37.9 12.2 18.3 70.1 62.6 24.5 33.7 65.8 21.5 5.1 40.5 8.2 28.6 53.8 11.4 27.3 35.0 70.6 33.9 16.8 31.0 34.7 56.5 26.3 82.8 120.3 23.1 12.0 55.5 39.2 181.0 52.7 32.1 30.9 43.2 DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012139, HPA012737, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane" Vesicles "HPA012139: , HPA012737: AB_1847293, HPA013154: AB_1847292" "unprognostic (9.96e-3)" "unprognostic (2.75e-1)" "unprognostic (3.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (2.65e-2)" "unprognostic (1.78e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.70e-6)" "unprognostic (2.24e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-3)" "unprognostic (1.08e-2)" 12.6 22.1 30.8 10.7 33.0 16.9 11.1 10.2 39.1 11.4 2.1 17.6 11.5 12.1 5.7 42.0 11.6 7.4 25.8 36.2 31.0 17.7 12.8 18.0 9.9 27.9 23.9 8.8 22.7 21.2 28.5 8.4 30.4 16.7 6.9 28.1 16.2 11.5 14.5 19.2 17.5 8.6 13.8 22.2 20.8 10.7 26.8 8.4 16.8 9.5 8.5 13.4 16.9 25.7 25.2 23.7 19.8 18.8 19.4 15.9 14.6 28.6 27.4 49.4 23.8 52.7 30.2 9.8 31.6 28.2 22.7 36.4 15.9 53.6 16.0 8.2 11.3 19.3 17.4 25.8 18.1 19.2 43.5 18.0 39.9 22.9 11.7 19.1 24.2 16.5 19.2 8.9 22.6 17.3 21.1 30.9 7.1 21.0 26.5 21.0 10.9 10.7 16.4 22.6 21.4 13.9 30.8 48.7 17.8 11.6 23.5 75.9 43.7 42.6 14.4 20.4 21.5 11.1 5.6 13.6 42.9 25.3 25.4 0.7 3.2 2.6 3.2 3.7 1.8 1.6 1.8 2.7 2.5 1.4 2.5 2.5 3.1 1.5 3.1 3.9 3.1 2.6 30.8 33.0 10.2 39.1 36.2 31.0 27.9 23.9 30.4 13.8 26.8 25.7 12.8 6.4 17.8 19.2 10.4 20.8 18.5 25.5 20.5 60.7 17.4 14.1 31.7 14.3 23.2 23.9 62.6 18.5 19.1 71.7 13.7 20.5 48.9 23.9 8.5 18.7 32.4 10.3 37.1 37.6 18.4 12.4 27.0 23.5 1.3 12.1 23.9 27.8 43.5 79.1 38.8 33.3 14.2 51.0 24.8 123.5 7.2 31.4 14.2 25.3 36.9 27.9 22.6 19.1 26.2 59.0 41.1 12.4 17.3 39.5 62.0 22.9 29.4 47.0 13.1 9.0 13.1 13.5 13.2 28.0 22.9 30.2 15.0 13.3 28.4 64.5 DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415871 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 81.5;retina: 52.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1038.1" "Cancer enriched" "Detected in many" 4 "glioma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 62.1;HEL: 165.8;K-562: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: AB_10611957, HPA054917: AB_2682641" "unprognostic (6.99e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-1)" "unprognostic (7.94e-7)" "unprognostic (1.59e-1)" "unprognostic (7.61e-3)" "unprognostic (1.87e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (4.14e-1)" "unprognostic (4.22e-3)" "unprognostic (1.53e-1)" "prognostic favorable (2.81e-4)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (8.67e-3)" 1.5 11.1 34.7 0.9 43.3 4.7 1.1 33.7 46.9 0.8 0.0 2.1 1.0 0.6 0.4 0.3 1.1 1.0 8.9 42.1 48.0 7.7 0.4 1.5 0.2 60.2 51.3 0.5 2.1 1.0 12.6 7.4 67.6 1.1 1.7 52.8 0.7 0.7 0.4 1.1 1.0 0.9 27.2 2.1 1.7 2.2 42.0 0.8 1.7 0.8 0.3 1.1 0.9 81.5 10.4 2.8 0.1 4.4 2.1 0.5 23.4 20.1 33.1 32.6 31.7 2.7 0.5 9.9 1.7 8.3 8.0 2.5 14.6 3.3 25.8 62.1 6.9 165.8 5.1 0.6 0.2 5.6 3.9 2.7 2.2 3.3 13.8 6.0 0.7 8.0 65.5 1.2 6.6 1.9 2.1 0.0 6.5 0.0 2.2 0.0 4.9 0.4 23.7 0.0 39.4 27.0 11.9 15.5 5.4 37.4 7.5 0.3 6.5 4.8 3.3 0.6 5.9 6.0 4.1 3.0 13.4 4.1 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 43.3 33.7 46.9 42.1 48.0 60.2 51.3 67.6 27.2 42.0 81.5 0.8 0.0 0.5 49.3 0.5 1.3 0.4 0.5 0.0 30.4 0.6 0.3 28.0 2.8 0.2 0.0 14.6 8.9 1.5 0.4 1.9 0.8 2.0 1.8 0.5 3.7 7.2 19.4 237.4 0.7 2.1 5.8 1.5 3.0 0.0 0.6 0.4 0.1 1.2 52.2 237.6 1.9 2.0 0.0 0.8 1.9 0.0 0.7 7.2 18.7 1.1 4.1 0.0 136.7 1038.1 0.4 0.2 0.0 0.9 1.7 0.0 7.2 1.2 21.6 0.0 0.2 8.5 1.7 2.5 0.0 0.3 7.4 0.6 6.9 0.6 0.2 DNAL4 "dJ327J16, PIG27" ENSG00000100246 "Dynein axonemal light chain 4" O96015 22 38778508-38794198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 124.1;Late spermatids: 210.7;Spermatocytes: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 64.0" "Low region specificity" "Detected in all" HPA003647 Approved Approved Nucleoplasm,Nucleoli,Centrosome,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Nucleoli, Cytosol" "HPA003647: AB_1078712" "unprognostic (8.45e-2)" "unprognostic (8.15e-3)" "unprognostic (2.35e-1)" "unprognostic (3.14e-3)" "unprognostic (3.74e-1)" "unprognostic (1.52e-1)" "unprognostic (6.46e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (2.07e-1)" "prognostic favorable (1.20e-6)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.83e-2)" 11.3 18.0 29.1 6.7 32.3 4.4 14.5 21.0 36.5 18.3 23.2 12.9 7.9 12.2 15.0 18.9 35.4 12.9 13.7 29.2 28.3 24.4 11.1 13.9 8.1 22.1 23.3 17.5 21.3 31.1 30.9 9.9 22.1 18.3 9.6 13.8 18.1 12.1 7.0 17.5 9.8 7.5 22.0 11.4 16.4 65.5 28.0 14.3 25.4 6.2 8.3 14.2 15.5 24.5 17.9 8.9 17.5 15.5 21.8 21.7 0.0 7.5 14.0 11.4 12.2 5.7 20.1 4.5 15.7 10.7 13.1 8.3 11.0 20.5 7.7 11.4 14.8 2.6 2.5 6.6 34.9 14.5 3.7 17.1 64.0 14.9 26.8 29.7 16.6 22.1 5.3 8.5 13.8 21.9 13.6 14.0 6.8 26.3 7.4 12.8 7.5 5.9 23.7 10.8 24.3 13.5 15.4 11.5 30.7 12.1 20.7 13.7 9.8 10.1 10.1 15.5 7.5 5.3 1.8 2.1 29.9 4.9 9.8 15.0 8.5 11.9 11.2 8.9 13.8 7.1 9.3 10.2 8.7 10.6 10.5 9.0 15.0 16.2 11.3 13.2 9.3 7.5 29.1 32.3 21.0 36.5 29.2 28.3 22.1 23.3 22.1 22.0 28.0 24.5 8.2 6.4 10.5 5.5 5.1 5.6 13.4 18.9 10.2 15.0 20.6 17.8 4.3 14.3 15.2 3.7 2.1 27.6 9.7 10.9 31.3 28.4 124.1 56.4 11.8 8.5 12.6 11.2 11.0 15.5 21.2 10.1 6.1 10.5 15.2 20.3 12.8 3.8 13.7 11.8 10.6 14.7 14.2 4.4 2.8 210.7 11.8 6.5 8.8 4.7 5.7 18.9 8.2 6.6 5.1 18.4 9.1 7.5 1.3 9.8 8.5 20.0 41.0 15.4 6.6 6.6 11.6 77.7 20.0 9.1 10.5 19.8 6.0 20.1 13.2 12.0 DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoli, Golgi apparatus, Cytosol" "Nuclear bodies" "HPA037878: AB_10675622, HPA058216: AB_2683640" "unprognostic (3.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.95e-6)" "unprognostic (3.92e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (8.67e-3)" "unprognostic (4.03e-2)" "unprognostic (5.07e-3)" "unprognostic (6.52e-2)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "prognostic favorable (6.15e-4)" 13.6 6.0 3.6 5.5 3.7 10.3 10.2 6.2 5.3 15.8 8.6 17.7 22.5 9.6 12.5 10.2 11.3 11.0 7.5 4.7 4.2 20.6 13.1 8.4 4.6 3.7 3.6 11.5 17.6 31.7 3.9 10.5 3.8 8.9 20.7 15.8 8.4 12.8 13.4 27.4 27.2 8.8 3.0 7.7 23.8 6.9 5.2 20.1 8.1 11.1 5.2 19.8 17.7 3.1 25.7 20.7 18.4 29.2 32.9 27.4 4.4 45.2 43.6 21.5 20.7 14.2 38.0 26.6 18.9 34.9 11.8 19.9 21.6 26.1 29.9 1.4 6.7 3.8 23.7 10.0 17.1 2.6 1.8 13.0 5.7 26.6 23.4 75.5 52.1 8.5 3.6 0.0 44.1 3.2 4.5 5.1 17.7 18.0 12.3 5.5 18.7 1.4 36.6 21.9 3.1 4.2 7.4 1.9 5.7 25.3 1.5 2.4 63.4 16.0 15.3 13.1 29.8 2.1 1.7 36.3 15.2 8.4 12.2 0.0 0.8 0.2 0.7 1.2 0.7 1.2 0.1 0.4 0.3 1.9 0.1 0.3 0.7 2.1 1.2 0.3 0.0 0.6 3.6 3.7 6.2 5.3 4.7 4.2 3.7 3.6 3.8 3.0 5.2 3.1 6.8 9.6 11.0 11.1 14.8 35.1 7.2 5.0 5.2 6.3 9.3 6.3 6.1 12.8 11.2 12.9 35.5 7.7 4.4 36.7 3.9 7.5 1.0 27.0 11.0 12.6 3.6 0.0 15.9 14.3 1.4 17.6 26.0 43.9 2.5 4.1 11.4 12.8 4.7 13.5 24.8 25.0 6.1 10.7 9.6 3.2 13.7 20.5 3.6 23.4 3.3 4.3 0.0 10.6 2.6 19.3 23.6 9.1 6.1 4.0 36.5 3.7 19.9 26.6 0.0 4.3 6.9 4.2 9.3 9.0 45.6 3.7 4.3 15.0 28.4 21.8 DNTTIP1 "C20orf167, dJ447F3.4, Tdif1" ENSG00000101457 "Deoxynucleotidyltransferase terminal interacting protein 1" Q9H147 20 45791954-45811427 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 124.8" "Group enriched" "Detected in all" 6 "dendritic cells: 43.3;granulocytes: 124.8;monocytes: 50.9" "Cell line enhanced" "Detected in all" "PC-3: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045496 Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA045496: " "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (4.52e-2)" "unprognostic (2.50e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (6.29e-2)" "unprognostic (7.16e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-3)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (3.18e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" 19.9 19.4 22.8 24.7 23.2 44.1 20.0 23.3 26.1 21.0 23.9 33.2 17.5 27.2 25.0 19.5 24.7 21.7 27.3 23.1 24.2 19.2 19.3 22.3 23.7 23.2 24.3 20.6 15.8 26.1 20.8 23.1 23.4 22.0 38.7 21.7 19.4 22.8 62.0 28.2 21.0 24.4 23.4 25.3 24.6 30.4 23.8 30.1 19.6 31.0 28.0 34.0 19.3 24.4 79.8 41.6 42.1 40.2 31.7 34.1 43.7 29.2 47.1 92.7 83.4 134.8 126.1 32.8 93.2 42.9 147.1 58.4 37.3 62.8 61.1 18.0 47.2 36.0 45.2 87.2 64.4 70.0 56.7 34.4 58.0 60.8 58.2 42.4 55.1 46.9 33.9 32.6 56.0 107.5 57.9 108.2 28.7 44.8 280.7 46.0 52.3 34.4 47.4 37.9 39.5 35.6 59.7 48.2 65.2 32.7 47.6 111.4 32.6 55.4 41.1 54.0 71.0 35.5 24.8 41.0 120.5 44.8 48.1 16.7 50.9 71.0 4.1 22.0 4.2 12.0 5.5 7.0 43.3 11.1 10.1 4.7 124.8 3.3 13.6 16.6 9.3 13.5 22.8 23.2 23.3 26.1 23.1 24.2 23.2 24.3 23.4 23.4 23.8 24.4 21.2 16.0 22.9 10.1 22.0 25.5 44.8 43.1 22.2 19.8 20.3 23.0 19.9 21.5 37.1 25.8 4.2 60.7 14.3 37.2 50.9 57.6 37.9 35.1 19.4 22.6 22.2 9.7 11.2 75.4 43.0 25.7 26.5 20.6 6.3 26.4 25.0 16.6 70.8 20.2 9.5 92.7 59.0 26.3 34.7 15.7 28.3 32.4 16.0 11.2 68.3 53.1 15.5 7.5 10.6 105.0 50.5 27.1 21.9 38.2 33.3 44.2 48.0 29.7 0.0 20.8 26.5 92.9 35.4 19.4 27.6 57.7 16.3 32.9 34.8 60.7 DNTTIP2 "ERBP, HSU15552, TdIF2" ENSG00000067334 "Deoxynucleotidyltransferase terminal interacting protein 2" Q5QJE6 1 93866284-93879918 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044502, HPA053707" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044502: AB_10960277, HPA053707: AB_2682236" "unprognostic (2.95e-3)" "unprognostic (3.84e-2)" "unprognostic (6.21e-3)" "unprognostic (1.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.92e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (7.94e-2)" "unprognostic (5.57e-3)" "unprognostic (2.69e-2)" "unprognostic (2.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.80e-5)" "unprognostic (2.59e-1)" "unprognostic (8.41e-2)" "unprognostic (2.25e-1)" "unprognostic (1.06e-2)" 5.0 3.7 4.9 3.5 5.2 15.3 5.0 10.3 6.7 3.5 5.6 3.4 2.7 4.0 6.3 4.4 3.5 4.5 4.5 5.5 5.4 4.2 5.0 3.7 5.5 4.8 4.9 4.3 3.4 3.8 2.1 4.6 5.1 3.7 3.6 4.2 2.9 3.0 8.9 5.5 2.7 3.7 3.8 4.5 3.6 4.5 5.3 4.3 4.7 5.0 5.2 6.5 2.8 6.8 14.3 6.6 7.2 7.8 6.9 6.2 11.1 9.4 6.6 11.0 9.4 7.3 6.1 18.8 12.2 9.9 13.8 7.7 11.9 11.2 15.6 11.4 6.6 15.4 11.3 11.0 7.2 17.4 5.3 6.8 11.9 11.9 9.8 5.5 7.9 6.0 18.6 6.0 15.1 6.3 12.2 11.3 14.2 6.3 10.6 7.0 15.6 7.2 11.3 10.8 8.7 7.7 9.8 14.4 10.5 9.2 6.2 12.6 7.7 8.8 9.2 10.2 15.9 6.4 9.3 15.3 5.1 13.6 5.9 9.7 5.7 11.6 6.4 8.3 7.7 8.2 5.8 5.8 5.1 8.4 5.3 6.9 8.0 9.6 8.5 3.5 6.4 6.8 4.9 5.2 10.3 6.7 5.5 5.4 4.8 4.9 5.1 3.8 5.3 6.8 98.9 57.7 78.2 3.6 66.7 54.4 163.0 57.9 43.3 33.9 27.5 38.9 73.0 11.5 91.2 12.9 58.4 52.0 110.2 17.3 21.5 74.3 53.8 85.1 72.0 74.2 8.4 20.6 6.8 60.3 44.4 54.3 38.2 122.4 119.4 36.6 25.7 19.4 38.1 20.2 7.7 14.5 46.8 29.5 72.1 11.0 25.7 75.8 23.2 8.4 52.1 29.2 48.4 3.5 7.2 88.6 20.1 25.9 50.1 96.7 17.2 19.6 85.1 34.4 19.7 90.7 79.0 62.8 65.9 40.0 50.6 55.8 87.7 44.4 23.1 112.0 DOC2A ENSG00000149927 "Double C2 domain alpha" Q14183 16 30005514-30023270 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.2;choroid plexus: 26.5;testis: 37.8" "Group enriched" "Detected in many" 4 "Early spermatids: 284.7;Late spermatids: 200.4" "Cancer enhanced" "Detected in many" "renal cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 13.1;MCF7: 10.8;REH: 11.0;SCLC-21H: 35.9;U-937: 17.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065676 Uncertain "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "Nucleoplasm, Nucleoli" "HPA065676: AB_2685528" "unprognostic (1.46e-3)" "unprognostic (3.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (4.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.66e-2)" "unprognostic (9.14e-2)" "unprognostic (3.90e-2)" "unprognostic (2.89e-2)" "unprognostic (1.28e-3)" "unprognostic (5.13e-2)" "unprognostic (8.29e-3)" "unprognostic (1.71e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" "unprognostic (2.61e-1)" 2.7 4.5 47.5 0.2 57.6 1.0 1.9 34.7 72.2 2.8 26.5 6.8 0.7 1.4 0.3 1.8 8.7 0.7 1.4 60.3 28.3 5.3 0.9 5.6 0.3 34.0 38.5 15.4 1.6 0.8 9.4 0.1 35.4 8.2 1.3 1.1 1.4 0.5 0.2 0.6 2.6 0.7 27.5 6.0 0.8 37.8 38.2 0.1 1.0 0.0 0.1 1.1 2.2 42.5 0.9 1.8 1.2 0.7 0.4 0.0 13.1 0.4 0.9 0.5 0.4 5.6 3.3 0.0 1.1 0.1 1.6 0.3 7.1 2.7 0.3 0.0 0.7 1.1 0.3 0.2 0.5 1.0 3.5 1.6 0.8 0.2 0.8 6.5 0.0 3.9 0.3 0.0 0.0 10.8 2.2 4.0 1.7 4.0 5.1 11.0 0.0 0.5 0.4 0.8 35.9 2.3 0.3 3.0 0.3 2.6 3.4 2.0 0.0 0.0 1.5 0.1 0.2 0.2 0.0 0.0 0.2 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.5 57.6 34.7 72.2 60.3 28.3 34.0 38.5 35.4 27.5 38.2 42.5 1.5 0.0 4.6 8.8 0.4 0.6 3.5 2.5 6.8 3.7 4.0 3.4 0.7 1.5 7.8 1.8 22.9 0.3 0.2 3.0 1.9 0.1 284.7 12.2 0.2 1.7 1.2 0.0 28.2 0.0 1.0 2.1 1.5 0.3 0.0 3.5 2.5 0.0 0.5 0.0 10.7 3.6 10.2 1.9 1.0 200.4 0.6 2.2 1.8 4.7 0.1 2.3 0.0 3.5 2.6 0.0 1.0 1.9 0.1 2.3 0.3 0.3 57.5 2.0 0.0 0.5 0.9 3.2 6.1 0.6 0.9 0.1 0.3 2.5 4.3 1.1 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DOCK8 "FLJ00026, FLJ00152, FLJ00346, ZIR8" ENSG00000107099 "Dedicator of cytokinesis 8" Q8NF50 9 214854-465259 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.0;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "Microglial cells: 506.8;monocytes: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 173.6" "Group enriched" "Detected in all" 4 "dendritic cells: 53.0;granulocytes: 173.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "Daudi: 52.9;HL-60: 53.3;MOLT-4: 50.1;NB-4: 83.7;REH: 61.9;RT4: 54.3;THP-1: 158.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003218, HPA073349" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "Nucleoplasm, Mitochondria, Cytosol" "HPA003218: AB_1078695, HPA073349: " "unprognostic (1.56e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-2)" "unprognostic (7.55e-3)" "unprognostic (3.31e-1)" "unprognostic (6.28e-3)" "unprognostic (1.79e-1)" "unprognostic (8.12e-2)" "unprognostic (2.72e-2)" "unprognostic (6.72e-2)" "unprognostic (1.90e-1)" "unprognostic (3.89e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.91e-1)" "prognostic favorable (6.89e-6)" 11.0 13.3 4.3 35.7 4.4 42.2 7.3 5.2 3.9 4.3 45.0 7.3 7.3 3.0 2.9 7.2 4.3 14.6 2.0 4.0 5.9 16.5 6.1 19.7 51.1 8.8 7.6 2.0 4.2 7.7 2.6 15.3 9.1 5.1 7.3 4.5 4.6 2.8 1.0 3.0 15.4 6.2 9.3 45.6 9.5 7.5 8.8 64.8 4.9 2.5 49.6 14.8 3.3 12.8 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 1.6 1.4 52.9 3.9 0.0 0.0 2.3 0.8 0.3 0.0 18.2 2.3 0.1 0.0 0.2 0.0 53.3 7.1 0.2 9.3 0.0 0.2 0.0 0.0 0.0 11.8 25.9 0.0 3.2 50.1 83.7 0.2 0.2 0.7 61.9 0.1 21.3 0.2 54.3 0.1 0.0 0.0 0.6 3.6 1.0 1.4 158.0 10.2 0.0 0.4 0.7 0.1 10.3 0.1 0.0 0.1 33.3 0.9 65.1 56.9 73.5 12.2 52.0 10.2 25.2 15.7 13.8 53.0 23.2 11.3 11.1 173.6 24.1 84.2 13.8 15.6 22.6 4.3 4.4 5.2 3.9 4.0 5.9 8.8 7.6 9.1 9.3 8.8 12.8 5.0 9.6 33.5 2.3 112.6 6.4 2.5 1.2 45.5 3.6 12.3 10.8 2.3 18.6 4.9 7.3 77.2 70.9 101.9 1.5 1.9 1.0 33.4 1.9 0.7 9.8 8.4 35.1 1.9 6.5 4.3 5.3 12.8 3.2 24.6 12.7 2.9 2.6 58.4 0.0 4.2 12.9 2.0 115.0 49.4 14.8 3.1 107.7 8.8 506.8 134.3 1.1 74.2 4.5 2.2 1.4 24.9 0.4 94.6 1.5 1.2 12.8 8.0 4.2 13.1 30.2 20.6 22.1 13.3 9.4 3.8 42.7 111.6 1.1 1.3 3.4 DOHH "HLRC1, MGC4293" ENSG00000129932 "Deoxyhypusine hydroxylase" Q9BU89 19 3490821-3500674 "Enzymes, Predicted intracellular proteins" "Hypusine biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041953, HPA076271" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nucleoli" "HPA041953: AB_10795386, HPA076271: " "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "unprognostic (8.63e-2)" "prognostic favorable (2.24e-4)" "unprognostic (3.66e-1)" "unprognostic (2.01e-2)" "unprognostic (9.45e-2)" "unprognostic (7.26e-2)" "unprognostic (4.65e-2)" "unprognostic (1.13e-1)" "prognostic favorable (3.58e-4)" "unprognostic (9.87e-3)" "unprognostic (1.14e-3)" "unprognostic (4.35e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (3.76e-3)" 7.5 8.8 15.6 4.4 18.9 8.9 6.8 18.9 18.3 6.2 9.9 8.2 17.8 7.6 0.5 11.0 6.7 1.2 12.6 14.7 15.2 11.1 10.9 6.4 3.2 20.6 19.2 6.5 8.5 2.5 8.4 2.2 18.8 7.5 1.0 1.3 6.9 2.1 18.9 10.5 11.5 1.3 16.5 7.9 8.7 8.1 17.6 2.1 5.9 2.2 1.6 8.3 6.9 24.0 18.6 22.4 3.1 7.1 1.6 2.0 15.0 17.4 3.6 8.0 6.5 31.9 7.6 15.3 13.2 2.4 7.5 19.3 4.6 6.1 1.5 21.5 24.5 15.1 13.3 37.7 6.7 20.7 19.9 2.3 5.7 8.2 3.3 2.8 4.3 15.6 34.1 16.4 3.7 22.3 20.3 23.3 19.1 7.1 29.2 25.4 7.6 21.3 5.3 11.1 20.0 15.5 12.7 10.8 18.4 1.3 15.0 11.0 9.9 10.9 14.4 29.0 31.7 21.9 17.4 20.1 12.4 46.6 12.7 1.2 6.7 2.4 7.6 8.1 9.4 11.1 10.1 14.9 11.0 16.5 14.1 12.3 0.4 10.0 8.9 14.1 13.2 5.9 15.6 18.9 18.9 18.3 14.7 15.2 20.6 19.2 18.8 16.5 17.6 24.0 9.5 6.4 2.2 2.0 15.5 23.6 22.6 13.2 12.5 17.2 12.4 10.0 7.7 11.5 7.1 5.5 10.4 30.9 7.6 27.9 21.5 22.2 8.6 10.9 7.9 13.2 13.1 23.2 4.9 21.3 29.9 13.6 16.3 7.8 13.4 10.5 11.7 10.0 21.6 25.2 5.1 17.6 24.4 7.9 9.3 23.8 14.0 9.3 19.6 1.9 16.9 12.7 15.5 4.5 30.0 24.7 17.2 15.1 16.0 28.4 10.8 28.9 4.6 12.4 0.0 16.2 13.6 12.6 12.7 14.5 27.6 34.8 12.1 13.6 27.2 18.7 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066767, HPA068706" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA066767: AB_2732751, HPA068706: AB_2732118" "unprognostic (6.35e-2)" "unprognostic (2.69e-1)" "unprognostic (2.63e-1)" "unprognostic (1.30e-3)" "unprognostic (3.55e-1)" "unprognostic (2.81e-3)" "unprognostic (8.90e-3)" "unprognostic (3.26e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-2)" "prognostic favorable (5.53e-4)" "unprognostic (3.20e-2)" "unprognostic (1.06e-1)" "prognostic favorable (6.88e-5)" "unprognostic (6.13e-3)" 9.6 14.3 6.6 6.3 6.3 1.5 7.8 6.7 6.7 7.4 8.6 7.5 7.6 9.3 13.5 8.6 8.9 7.9 10.5 6.5 7.1 9.1 10.5 9.1 6.8 6.9 7.6 6.7 14.5 16.8 5.9 9.3 7.3 10.0 6.6 4.4 12.0 10.0 6.7 9.9 7.5 9.4 6.5 8.0 10.6 14.5 7.6 5.1 7.8 7.1 6.6 8.6 5.9 6.8 11.7 42.5 14.8 22.0 42.6 22.2 20.0 23.7 38.1 28.5 21.0 33.7 17.9 6.4 12.3 34.6 40.3 80.3 20.3 29.6 14.7 10.7 17.8 8.0 27.4 24.5 43.0 8.8 13.5 31.1 27.0 30.8 16.8 16.7 28.1 9.1 19.7 10.0 31.3 56.9 7.3 7.3 19.0 33.0 26.0 7.2 19.5 25.1 25.7 17.3 13.5 15.1 31.4 25.6 14.1 13.7 44.8 11.4 23.6 25.6 9.2 32.5 19.8 9.4 25.0 6.4 24.2 8.0 19.9 2.7 15.4 6.9 11.2 15.3 10.1 11.8 9.9 12.3 16.6 12.5 12.8 13.2 2.2 13.0 21.2 9.3 16.8 10.5 6.6 6.3 6.7 6.7 6.5 7.1 6.9 7.6 7.3 6.5 7.6 6.8 8.5 6.4 4.1 2.9 2.6 1.8 3.6 13.9 4.6 9.1 4.4 4.3 3.5 10.0 10.9 7.3 8.4 25.6 3.5 5.2 0.0 15.7 15.1 5.9 7.2 9.2 1.2 3.6 1.2 14.2 16.4 8.1 5.1 3.6 1.3 7.5 16.1 9.2 13.5 5.0 2.2 3.5 12.2 5.2 2.7 3.7 12.2 2.9 3.6 1.9 2.8 10.7 5.2 2.5 1.7 11.1 7.5 6.0 1.5 4.4 7.5 9.0 11.4 7.1 0.0 7.0 15.7 33.8 15.1 3.3 1.3 18.2 2.3 15.8 5.7 2.1 DONSON "B17, C21orf60, C2TA, DKFZP434M035" ENSG00000159147 "DNA replication fork stabilization factor DONSON" Q9NYP3 21 33559542-33588706 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.3;Erythroid cells: 42.1;Spermatocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039558, HPA049033" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" Cytosol "HPA039558: AB_2676570, HPA049033: AB_2680608" "unprognostic (9.90e-3)" "unprognostic (1.01e-3)" "unprognostic (6.58e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.22e-4)" "unprognostic (4.00e-2)" "unprognostic (5.93e-3)" "prognostic favorable (2.17e-4)" "unprognostic (1.25e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.77e-2)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (8.83e-2)" 5.5 2.9 5.8 5.5 6.5 10.9 4.1 7.9 7.5 8.5 4.2 5.2 5.4 5.7 2.4 5.0 7.0 5.5 4.4 5.4 6.5 3.9 7.9 4.6 10.5 6.7 6.2 10.8 3.4 5.6 5.5 6.6 6.7 4.8 6.3 13.3 3.5 3.4 4.4 8.5 6.1 4.5 5.7 3.6 4.9 21.2 6.5 10.6 3.5 4.8 9.2 4.7 6.2 8.6 67.9 15.5 34.8 30.4 10.7 18.5 23.9 53.7 23.2 41.2 45.1 41.9 19.7 40.5 13.9 28.3 30.6 20.0 43.6 20.2 45.1 36.5 36.5 73.8 34.9 41.5 8.1 39.0 18.2 13.9 5.7 44.4 11.1 13.1 25.1 19.8 67.0 65.2 35.4 14.7 34.0 17.2 35.9 34.8 17.3 33.2 68.4 41.3 21.3 19.0 36.0 14.8 82.1 25.3 23.1 17.1 34.9 19.4 16.4 38.0 25.3 28.6 37.7 56.8 58.1 59.3 22.1 52.1 43.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 6.5 7.9 7.5 5.4 6.5 6.7 6.2 6.7 5.7 6.5 8.6 6.3 3.2 1.9 10.4 4.8 8.2 8.1 3.1 5.2 2.8 5.6 5.7 3.9 7.2 2.3 3.7 10.4 13.2 7.8 3.0 1.9 3.3 57.3 3.0 6.6 8.0 1.2 42.1 9.7 4.7 27.9 6.9 7.1 4.4 8.2 7.5 7.5 6.2 8.9 6.7 11.2 4.2 6.1 3.4 6.3 25.3 10.2 5.5 7.2 4.7 4.0 2.1 4.1 7.5 12.7 3.9 2.5 13.9 19.3 5.7 2.9 4.4 2.8 3.6 0.0 4.4 7.6 62.3 33.5 7.6 9.8 16.6 7.6 3.0 6.8 9.2 DPF1 "BAF45b, NEUD4, neuro-d4" ENSG00000011332 "Double PHD fingers 1" Q92782 19 38211006-38229714 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 23.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.9;Early spermatids: 25.4;Excitatory neurons: 24.6;Horizontal cells: 45.4;Inhibitory neurons: 16.3;Late spermatids: 23.4" "Group enriched" "Detected in some" 5 "glioma: 5.6;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 19.7;SCLC-21H: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049148 Enhanced Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" Mitochondria "HPA049148: AB_2680653" "unprognostic (7.72e-2)" "unprognostic (2.33e-1)" "unprognostic (5.38e-2)" "unprognostic (4.11e-3)" "unprognostic (8.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-4)" "unprognostic (1.40e-2)" "unprognostic (2.72e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-3)" "unprognostic (2.87e-2)" "unprognostic (1.11e-16)" "unprognostic (2.56e-1)" "unprognostic (3.75e-1)" "unprognostic (6.96e-2)" "unprognostic (8.20e-4)" 0.1 0.3 12.7 0.4 14.9 0.1 0.1 2.2 23.4 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.0 0.4 16.9 9.9 0.1 0.0 0.3 0.1 1.9 4.4 0.3 0.1 0.0 2.5 0.1 2.4 0.1 0.0 2.4 0.2 0.0 0.2 0.3 0.1 0.2 2.0 0.1 0.1 2.4 9.5 0.2 0.0 0.0 0.1 0.1 0.1 14.8 4.6 3.8 15.8 11.7 1.1 0.8 1.6 4.8 2.7 8.0 6.7 2.7 0.4 7.5 3.2 3.7 3.2 2.8 19.7 2.6 3.6 7.2 3.9 2.5 2.0 1.1 0.4 1.9 2.1 0.9 0.1 4.7 1.5 1.0 1.5 5.5 5.6 0.4 7.7 6.4 4.1 0.5 2.9 1.3 4.4 7.5 8.0 1.6 0.8 1.4 22.9 7.8 5.4 0.5 1.0 1.9 2.4 0.4 1.8 11.5 3.7 2.8 4.4 2.9 10.3 9.9 6.1 2.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 14.9 2.2 23.4 16.9 9.9 1.9 4.4 2.4 2.0 9.5 14.8 0.4 0.0 0.0 3.3 0.1 2.3 0.1 1.1 0.0 17.9 0.2 0.6 1.2 0.0 0.1 0.0 8.4 0.1 0.0 0.1 0.0 0.0 25.4 1.5 2.2 0.9 0.0 0.0 24.6 0.0 2.0 1.5 0.0 0.7 0.0 4.3 0.4 0.0 0.2 45.4 16.3 0.0 0.0 0.3 0.4 23.4 0.6 0.1 0.0 1.0 0.0 3.3 0.0 12.5 4.8 0.1 0.0 2.6 0.0 0.1 0.0 0.1 1.4 3.1 0.0 0.7 1.9 6.7 12.6 0.0 1.1 0.1 0.2 1.6 0.0 0.1 DPH6 "ATPBD4, MGC14798" ENSG00000134146 "Diphthamine biosynthesis 6" Q7L8W6 15 35217345-35546193 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 91.7;Oligodendrocytes: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042976, HPA055496" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042976: AB_10964890, HPA055496: AB_2682835" "unprognostic (9.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (9.94e-2)" "unprognostic (1.76e-1)" "unprognostic (1.49e-3)" "unprognostic (7.92e-3)" "unprognostic (1.13e-1)" "unprognostic (4.65e-6)" "unprognostic (9.70e-2)" "unprognostic (5.61e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" 8.6 7.5 3.7 4.9 4.7 5.4 10.8 4.6 5.0 6.8 3.6 6.7 6.1 7.9 10.7 9.6 8.1 6.0 10.2 3.6 4.7 10.4 8.1 5.3 5.3 4.6 4.4 9.7 14.3 8.7 5.9 8.1 4.8 5.8 7.0 8.9 6.7 6.1 10.8 9.7 6.6 6.4 4.3 6.3 6.8 5.9 3.9 7.0 10.8 6.9 7.4 8.0 7.1 5.7 16.9 8.9 14.7 12.5 2.6 11.7 14.3 6.2 10.8 14.7 7.6 11.9 15.5 5.2 14.8 5.7 17.9 19.0 17.2 17.9 17.5 4.1 10.7 19.6 9.9 18.9 15.3 10.6 12.1 9.9 22.2 5.9 28.5 9.0 14.4 11.0 21.8 20.6 13.6 6.6 13.0 9.8 13.0 25.4 8.1 16.0 13.7 7.2 12.9 21.0 10.7 10.4 11.6 12.8 10.7 8.5 44.6 14.4 4.4 14.2 13.8 14.4 10.0 18.2 31.3 13.4 12.3 17.7 13.9 0.0 6.7 0.3 6.0 6.7 7.7 8.9 8.1 8.4 6.7 6.3 10.3 9.3 0.3 14.7 6.2 5.8 5.8 4.5 3.7 4.7 4.6 5.0 3.6 4.7 4.6 4.4 4.8 4.3 3.9 5.7 15.9 16.0 7.5 91.7 18.7 31.0 20.0 19.8 24.5 29.2 12.0 16.6 15.8 18.6 17.2 9.2 39.6 26.7 9.3 7.5 13.7 16.3 2.2 10.7 13.7 10.0 5.4 16.8 28.0 24.1 23.5 12.0 21.4 13.3 3.8 21.1 5.7 7.4 17.5 18.5 47.0 7.4 14.2 10.3 12.9 3.3 14.0 9.8 16.0 44.0 14.3 15.0 11.3 71.9 101.5 18.7 7.1 6.8 6.9 8.9 13.4 19.9 7.6 24.2 0.0 18.9 14.0 9.8 14.0 21.2 23.2 22.6 9.9 21.9 10.5 13.4 DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326141-109337572 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.2;testis: 4.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Erythroid cells: 16.4;Extravillous trophoblasts: 17.2;Spermatogonia: 11.7;Syncytiotrophoblasts: 6.2" "Cancer enriched" "Detected in single" 218 "testis cancer: 59.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.3" "Group enriched" "Detected in some" 4 "HAP1: 89.7;NTERA-2: 327.5;SuSa: 120.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: AB_2674535, HPA035250: AB_2674536" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (3.80e-1)" "unprognostic (2.53e-1)" "unprognostic (8.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (9.83e-2)" "unprognostic (2.02e-2)" "unprognostic (6.60e-2)" "unprognostic (2.48e-2)" "unprognostic (3.03e-8)" "unprognostic (5.28e-2)" "unprognostic (5.04e-2)" "unprognostic (5.56e-2)" "unprognostic (3.85e-2)" 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 12.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 89.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 327.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.5 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 22.3 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 16.4 0.1 0.0 17.2 0.5 0.0 0.0 1.3 0.0 0.4 1.6 1.7 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.7 0.0 0.0 0.9 0.3 0.3 11.7 0.0 0.0 6.2 0.5 0.2 0.0 0.3 DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024339, HPA024780" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA024339: , HPA024780: AB_10600869" "unprognostic (1.45e-1)" "unprognostic (2.89e-3)" "unprognostic (3.41e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.28e-1)" "unprognostic (5.54e-2)" "unprognostic (4.94e-2)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.72e-2)" "unprognostic (9.38e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" 11.5 12.3 7.3 6.6 10.5 5.1 12.5 9.7 9.4 13.6 8.0 8.6 6.7 12.3 10.5 7.6 11.2 10.0 15.4 6.5 10.1 14.5 15.8 9.1 6.9 9.9 9.0 16.7 9.4 26.4 6.4 12.6 10.3 11.6 9.0 13.0 10.2 9.0 7.2 9.4 7.9 9.5 9.6 11.1 13.1 9.6 8.9 7.0 16.1 9.3 5.8 8.6 8.5 14.4 24.4 15.5 26.1 16.4 25.9 33.3 14.4 21.5 20.3 19.8 19.4 7.3 35.0 5.4 25.8 20.8 13.3 25.0 16.0 16.9 32.7 12.2 12.8 25.3 15.1 12.2 30.1 10.9 5.1 22.2 14.0 16.8 16.2 23.2 24.3 16.0 18.0 9.0 23.3 15.3 20.9 20.5 10.2 27.9 17.2 14.8 17.9 10.9 19.1 18.9 12.8 28.7 17.2 3.6 16.8 15.9 22.8 13.6 24.0 20.5 12.6 23.1 18.1 9.9 13.1 14.8 15.4 18.7 29.6 0.7 0.5 0.0 1.0 0.6 1.4 1.2 1.0 1.6 1.0 0.3 1.1 1.4 0.4 1.4 0.6 1.2 0.4 0.7 7.3 10.5 9.7 9.4 6.5 10.1 9.9 9.0 10.3 9.6 8.9 14.4 21.1 16.0 16.3 20.5 6.3 9.8 14.1 11.6 15.9 19.6 16.2 12.1 26.0 11.5 13.0 40.5 4.2 16.7 3.7 8.5 1.9 8.9 2.1 13.7 20.3 19.0 7.3 9.7 13.2 10.0 11.9 20.4 12.2 13.7 3.8 23.1 65.0 27.5 9.6 13.5 18.3 11.5 10.2 14.8 11.9 5.0 17.4 8.3 10.6 25.3 5.5 11.9 9.2 23.6 39.7 13.0 6.4 18.4 7.9 15.6 10.7 10.7 18.8 17.6 6.6 13.4 14.9 11.9 9.8 16.6 12.1 9.2 7.8 32.6 12.0 14.1 DRG1 NEDD3 ENSG00000185721 "Developmentally regulated GTP binding protein 1" Q9Y295 22 31399604-31530634 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 160.2" "Group enriched" "Detected in all" 5 "Early spermatids: 798.4;Late spermatids: 651.5;Spermatocytes: 469.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001218 Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 22000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA001218: AB_1078704" "unprognostic (4.94e-1)" "unprognostic (3.33e-2)" "unprognostic (1.17e-3)" "unprognostic (5.26e-2)" "unprognostic (4.66e-2)" "unprognostic (3.49e-3)" "prognostic unfavorable (7.71e-4)" "unprognostic (3.68e-2)" "unprognostic (1.54e-1)" "unprognostic (2.32e-3)" "unprognostic (8.69e-3)" "unprognostic (1.55e-3)" "unprognostic (4.80e-2)" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (3.89e-1)" "unprognostic (2.25e-1)" 31.4 32.6 22.6 21.4 23.9 32.3 35.1 27.0 31.6 27.3 22.8 24.7 22.6 27.8 38.7 27.4 32.7 19.5 44.6 23.7 24.6 35.9 37.9 20.9 29.2 23.9 23.7 35.0 34.1 38.4 18.6 35.7 25.0 25.0 30.0 30.1 30.5 28.8 100.5 23.7 21.3 34.1 24.5 20.1 24.2 160.2 22.7 40.4 34.5 85.1 38.3 30.8 20.6 26.4 80.3 61.3 73.9 63.3 64.4 75.2 61.5 70.2 81.7 125.7 104.4 100.3 38.3 111.2 38.6 86.9 60.3 64.5 128.5 82.8 134.4 52.0 152.0 71.9 64.9 99.6 91.4 174.2 65.1 65.6 60.9 103.7 152.9 64.6 87.5 61.6 93.9 48.1 97.2 88.0 75.7 88.4 62.1 114.0 65.9 98.7 118.9 97.3 82.1 68.6 80.8 50.4 78.5 79.8 107.2 70.8 59.7 77.2 50.6 57.7 79.3 59.1 81.3 67.2 78.5 108.6 57.0 77.7 77.4 25.0 43.3 46.0 34.3 49.7 39.6 53.6 36.6 43.0 45.2 39.4 40.5 39.8 9.8 46.7 37.5 39.6 50.9 47.0 22.6 23.9 27.0 31.6 23.7 24.6 23.9 23.7 25.0 24.5 22.7 26.4 22.0 19.2 15.4 3.9 29.4 38.6 40.8 77.2 29.6 18.7 27.2 27.2 52.4 35.8 37.6 27.6 25.0 126.4 20.6 22.5 64.6 56.4 798.4 23.7 24.4 34.4 11.4 37.8 10.3 45.4 104.5 33.2 21.4 21.1 33.7 27.1 35.7 36.9 60.4 15.2 11.2 31.0 48.8 31.1 24.0 651.5 35.8 22.9 17.8 7.5 39.2 27.6 33.0 9.5 11.1 42.7 27.0 37.2 27.1 48.7 42.9 60.3 28.7 18.4 59.2 35.4 36.1 469.3 92.1 33.1 32.1 117.1 25.5 26.2 41.0 45.3 DRG2 ENSG00000108591 "Developmentally regulated GTP binding protein 2" P55039 17 18087892-18107970 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007716 Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "Vesicles, Cytosol" Nucleoplasm "HPA007716: AB_1078705" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.26e-3)" "unprognostic (7.86e-2)" "unprognostic (8.85e-2)" "unprognostic (5.72e-2)" "unprognostic (8.49e-2)" "unprognostic (1.25e-1)" "unprognostic (2.88e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (3.10e-1)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" 19.3 19.1 14.2 12.8 14.8 15.9 19.6 14.8 15.0 21.6 13.6 19.4 14.8 22.3 12.9 21.6 19.8 12.6 19.8 14.9 15.7 18.5 16.6 15.7 18.4 15.2 15.4 22.5 19.6 15.8 17.8 12.3 16.1 20.1 10.0 5.2 17.0 15.2 36.6 20.3 17.4 13.7 15.4 19.8 17.9 8.9 14.9 16.0 18.4 16.5 14.9 20.0 18.3 16.5 37.1 51.1 17.4 17.3 31.1 31.7 33.1 24.8 24.7 40.0 37.0 55.5 21.8 35.5 31.8 29.4 21.2 38.9 28.5 35.1 27.4 32.1 74.2 16.0 26.5 31.5 33.4 14.3 24.2 36.4 30.5 39.1 33.0 22.9 38.5 46.8 27.6 13.7 23.6 42.5 38.7 25.8 12.9 51.4 36.1 41.5 41.8 66.7 24.3 21.6 9.9 28.0 25.2 15.2 31.9 102.8 30.0 21.4 29.2 19.6 18.3 23.0 42.8 15.5 19.4 20.1 27.9 26.2 36.6 17.7 21.1 23.6 24.6 23.3 20.2 14.9 17.8 20.0 24.6 17.7 16.9 18.7 2.8 28.2 30.5 13.8 24.9 19.3 14.2 14.8 14.8 15.0 14.9 15.7 15.2 15.4 16.1 15.4 14.9 16.5 23.8 0.0 12.4 8.5 19.5 16.7 19.9 21.2 11.4 14.9 18.8 23.0 3.9 24.3 13.2 7.3 2.1 37.5 26.3 20.1 29.4 29.4 7.3 12.8 19.3 20.8 21.6 10.1 11.9 27.1 40.8 19.4 17.9 12.9 12.0 32.6 16.4 19.4 32.2 6.7 10.0 19.7 16.2 21.4 12.2 14.2 21.5 18.0 12.4 8.4 23.9 19.6 23.7 4.0 8.0 24.8 16.2 24.5 22.9 17.4 31.4 31.8 9.3 13.4 6.6 22.0 21.7 12.1 13.0 18.2 11.6 39.3 21.9 33.9 24.5 14.4 DRGX "DRG11, PRRXL1" ENSG00000165606 "Dorsal root ganglia homeobox" A6NNA5 10 49364066-49396089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 19 "adrenal gland: 5.4;brain: 10.4" "Cell type enhanced" "Detected in some" "Langerhans cells: 1.2;Melanocytes: 1.8" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in some" 12 "medulla oblongata: 10.1;pons: 10.4;spinal cord: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "RH-30: 11.6;SH-SY5Y: 46.2;U-2197: 17.7" "Region enriched" "Detected in single" 6 "pons and medulla: 3.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 4.0;hippocampal formation: 1.6;medulla oblongata: 2.4;spinal cord: 3.7" HPA043978 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA043978: AB_10961154" "unprognostic (1.42e-2)" "unprognostic (5.68e-2)" "unprognostic (3.92e-2)" "unprognostic (1.23e-2)" "unprognostic (1.74e-3)" "unprognostic (1.58e-1)" "unprognostic (4.54e-2)" "unprognostic (3.74e-2)" "unprognostic (8.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.09e-2)" 0.1 5.4 0.0 0.2 0.1 0.1 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 10.1 0.7 0.0 0.0 0.0 0.2 0.0 10.4 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 8.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 46.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 17.7 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.1 0.3 10.1 0.7 10.4 8.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.2 0.8 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.8;Spermatocytes: 115.5;Spermatogonia: 75.1;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 5.9 9.9 4.2 7.5 4.2 14.3 8.6 3.9 4.5 5.0 5.2 9.2 6.8 4.4 9.3 7.9 4.1 4.4 5.1 4.3 4.4 4.8 9.1 6.3 12.8 4.0 3.9 4.3 4.3 5.5 3.5 8.8 4.1 6.5 10.8 10.7 5.9 6.3 4.0 8.0 7.8 6.3 3.9 9.6 7.3 23.3 4.1 16.4 5.1 4.8 14.3 4.4 4.7 4.7 36.7 29.1 35.7 29.5 14.0 18.0 24.7 42.9 35.1 63.9 70.2 52.5 44.4 39.3 27.4 23.0 69.1 45.8 33.3 32.7 60.3 18.2 22.7 78.3 26.2 36.1 3.0 46.2 34.0 7.0 9.4 43.7 13.8 10.4 31.5 42.4 30.9 33.7 41.7 25.3 59.2 34.5 16.8 63.3 55.1 46.1 109.4 28.4 16.2 20.5 37.8 16.9 52.9 53.7 25.8 26.3 55.9 30.5 16.4 60.1 35.0 56.9 46.1 27.3 39.1 46.4 49.8 40.8 42.6 53.4 6.4 14.5 7.4 11.0 8.4 14.6 8.1 10.3 7.1 18.4 10.1 9.0 11.9 11.1 10.1 46.9 12.2 6.7 4.2 4.2 3.9 4.5 4.3 4.4 4.0 3.9 4.1 3.9 4.1 4.7 6.5 6.4 4.4 1.6 10.3 5.0 11.4 7.6 3.4 8.0 8.7 7.6 5.4 2.8 8.6 5.5 29.2 49.8 9.8 9.2 7.9 6.8 10.6 5.5 5.9 8.1 2.4 22.1 6.3 6.4 30.4 8.4 20.9 9.4 3.8 21.8 7.9 6.2 14.7 6.7 4.4 13.6 4.1 6.3 4.6 8.0 8.7 6.7 1.8 5.6 7.4 6.0 7.2 3.0 3.6 5.1 5.4 7.5 22.9 7.1 7.7 3.6 8.2 17.5 0.0 5.3 8.2 115.5 75.1 12.3 7.2 47.5 7.7 6.9 13.6 11.0 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493290-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 461.9;choroid plexus: 120.6;heart muscle: 150.0;skeletal muscle: 166.9;tongue: 209.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1756.1;Excitatory neurons: 506.0;Inhibitory neurons: 650.9;Oligodendrocyte precursor cells: 491.6;Oligodendrocytes: 367.4" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 37.7;NTERA-2: 42.0;SCLC-21H: 51.9;U-87 MG: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" 11.6 6.6 252.7 5.4 248.2 0.8 9.6 243.3 260.1 5.4 120.6 22.4 3.9 8.1 20.5 22.9 11.7 9.4 150.0 250.1 423.0 2.3 2.2 6.6 2.3 461.9 326.9 7.0 18.1 2.4 10.8 4.1 360.4 23.6 7.6 19.8 11.3 25.3 166.9 2.7 8.4 19.4 308.1 4.8 6.8 6.1 269.2 0.5 12.3 209.9 2.0 32.0 5.2 331.0 0.7 0.5 17.3 0.0 9.5 25.1 2.6 3.2 14.8 0.6 1.7 3.8 0.2 0.1 8.9 1.9 15.3 1.1 2.1 7.5 1.8 0.0 10.7 0.1 0.9 5.7 7.1 0.2 0.2 19.2 1.8 11.9 4.5 14.2 6.7 0.1 2.4 1.9 3.8 37.7 0.1 0.2 42.0 0.6 8.1 0.1 7.7 24.1 0.9 0.3 51.9 6.9 0.0 1.7 4.9 23.8 21.8 6.3 0.5 16.7 9.9 0.3 5.2 1.3 2.0 1.0 52.5 0.0 8.4 1.0 0.7 0.0 0.8 0.0 1.1 0.8 1.5 1.1 3.5 0.7 1.6 1.3 0.3 0.8 0.0 0.1 4.3 1.0 252.7 248.2 243.3 260.1 250.1 423.0 461.9 326.9 360.4 308.1 269.2 331.0 5.1 0.0 1.1 1756.1 0.1 1.5 0.1 0.8 0.0 18.3 22.2 12.3 134.3 27.1 1.4 0.0 6.2 0.1 0.4 0.0 5.9 12.6 3.1 7.0 2.6 6.4 0.0 0.0 506.0 25.1 0.1 5.7 0.0 0.4 0.0 2.3 0.0 0.2 9.0 1.7 650.9 0.1 4.1 4.0 21.5 3.7 5.9 8.0 5.4 105.9 0.9 34.0 0.0 491.6 367.4 8.0 0.0 0.4 0.0 1.8 0.1 2.0 7.1 3.8 13.1 22.7 17.3 0.9 4.8 0.2 1.0 0.0 0.2 0.3 0.2 0.2 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056709-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;lymphoid tissue: 11.8" "Group enriched" "Detected in many" 6 "Astrocytes: 48.3;Horizontal cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 109.1;REH: 45.1;U-698: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: AB_2682769" "unprognostic (2.13e-3)" "unprognostic (3.20e-3)" "unprognostic (4.24e-4)" "unprognostic (2.01e-1)" "unprognostic (7.48e-3)" "unprognostic (1.59e-3)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (9.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.41e-2)" "unprognostic (4.70e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-3)" 9.0 1.7 6.5 5.7 6.8 2.7 6.4 3.2 5.9 2.4 0.2 0.8 1.3 1.5 0.3 0.9 1.8 0.8 1.2 5.2 11.1 3.5 8.9 0.8 11.1 5.2 8.8 0.4 1.6 0.0 3.3 0.3 5.1 0.8 0.1 2.9 2.6 0.3 0.5 1.0 3.5 0.3 3.7 11.8 0.9 1.9 10.5 0.5 2.2 0.1 6.0 0.5 0.6 2.4 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 109.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.3 4.6 0.0 2.0 0.2 0.0 45.1 0.2 2.6 0.0 0.0 2.7 7.1 0.4 0.4 2.5 0.0 0.1 0.2 1.2 0.0 4.0 0.0 0.1 0.5 0.2 110.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.5 6.8 3.2 5.9 5.2 11.1 5.2 8.8 5.1 3.7 10.5 2.4 0.7 0.0 0.0 48.3 8.8 1.0 0.0 0.0 0.0 4.7 0.2 0.6 0.7 0.0 0.0 1.8 8.4 0.0 0.3 0.1 7.9 2.5 0.7 0.7 17.5 1.7 0.0 0.0 10.6 0.0 0.0 4.5 0.5 0.4 7.0 0.0 0.4 12.4 0.8 171.6 13.8 0.1 0.0 0.3 0.6 1.7 7.8 0.2 3.6 2.8 0.0 11.4 2.1 13.0 1.0 0.2 0.1 7.5 2.5 0.0 0.0 0.2 0.0 2.8 0.0 0.4 1.3 0.8 2.4 0.0 0.4 0.0 2.2 0.8 0.0 0.0 DTX3 "FLJ34766, RNF154" ENSG00000178498 "Deltex E3 ubiquitin ligase 3" Q8N9I9 12 57604622-57609804 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 70.7" "Cancer enriched" "Detected in all" 4 "glioma: 54.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "NK-cells: 1.0;T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059654 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No No "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA059654: AB_2684097" "unprognostic (2.31e-2)" "unprognostic (8.80e-2)" "unprognostic (2.06e-2)" "unprognostic (3.68e-1)" "unprognostic (3.35e-1)" "unprognostic (2.58e-2)" "unprognostic (6.91e-2)" "prognostic favorable (9.87e-4)" "unprognostic (1.84e-1)" "unprognostic (4.26e-2)" "prognostic favorable (1.44e-4)" "unprognostic (8.62e-2)" "unprognostic (5.44e-3)" "unprognostic (7.99e-2)" "unprognostic (8.81e-2)" "unprognostic (9.51e-2)" "unprognostic (3.48e-2)" 36.6 58.2 117.1 15.8 120.2 7.2 36.4 117.5 138.2 97.6 115.0 117.4 11.5 95.5 50.7 24.2 92.0 24.5 67.6 124.5 111.4 63.8 12.3 37.2 21.2 107.8 112.1 124.3 41.9 39.4 145.1 28.1 108.6 82.1 16.8 80.8 31.4 48.2 21.0 21.1 46.2 48.5 105.3 46.0 51.0 29.0 112.6 23.6 75.9 16.6 15.5 65.0 60.7 119.0 8.8 22.7 65.9 0.1 0.0 0.1 0.4 13.8 35.4 29.7 30.0 11.8 36.5 12.3 20.5 30.0 0.3 14.2 0.0 1.7 20.9 31.1 4.1 7.1 39.4 12.5 49.4 0.0 0.1 24.5 16.7 22.8 0.3 84.4 33.6 0.1 0.0 40.9 23.1 19.2 38.4 0.3 52.1 7.2 2.0 0.0 55.1 0.7 2.8 22.7 47.7 75.5 10.9 3.1 7.0 15.8 38.4 18.9 0.1 38.6 15.3 17.9 20.2 66.2 53.6 0.2 24.8 0.1 20.6 0.0 0.0 0.0 2.5 0.0 0.6 0.1 0.9 1.2 0.1 0.1 0.8 1.6 0.0 1.0 0.0 0.3 2.2 1.2 117.1 120.2 117.5 138.2 124.5 111.4 107.8 112.1 108.6 105.3 112.6 119.0 4.9 16.0 15.6 25.8 2.9 6.2 10.0 8.7 21.1 47.8 12.2 19.9 11.0 11.5 10.5 12.9 50.1 0.5 10.6 0.5 13.7 8.2 0.9 17.8 17.4 8.5 15.6 4.4 29.9 1.9 0.3 15.1 6.1 5.5 5.7 17.2 15.0 0.6 0.6 70.7 29.3 0.9 10.2 2.0 2.1 2.8 34.2 1.6 3.6 8.4 0.8 27.4 36.0 25.1 19.0 2.6 0.0 31.6 5.8 7.1 0.0 4.6 30.9 42.0 46.0 11.5 37.5 4.6 5.7 2.8 2.8 1.2 10.4 16.8 0.7 3.5 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742089 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 32.9" "Cell type enhanced" "Detected in many" "granulocytes: 133.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 19.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 102.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favorable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 3.8 2.4 4.3 5.2 7.4 25.0 6.0 7.7 5.3 4.5 4.7 8.0 1.4 3.6 1.2 6.0 6.4 6.6 2.6 4.5 4.5 1.4 32.9 6.2 9.1 7.1 6.0 1.6 17.0 1.2 1.2 3.8 5.8 2.7 4.1 14.9 6.3 0.9 22.9 6.1 3.9 8.9 3.8 6.1 2.5 3.1 9.0 5.6 4.4 3.6 7.6 6.1 2.7 13.5 15.2 6.4 0.5 0.4 45.4 22.6 0.5 10.1 25.9 16.2 12.5 0.3 4.2 11.6 3.3 26.1 11.9 102.3 2.2 9.8 14.0 30.5 1.2 20.4 3.0 1.8 10.6 9.1 13.3 31.9 7.0 17.6 17.8 7.5 0.6 3.0 2.1 4.0 16.0 0.3 1.8 7.2 1.5 3.2 0.7 1.1 28.5 0.9 5.7 9.1 37.4 3.0 1.3 1.2 43.6 5.6 2.1 5.5 3.6 8.1 2.2 12.6 12.4 6.8 5.1 6.2 12.8 4.1 8.9 8.2 5.5 0.3 4.5 4.6 3.9 0.8 2.9 3.1 7.0 0.9 1.0 1.7 0.5 19.7 1.9 0.2 16.9 2.2 4.3 7.4 7.7 5.3 4.5 4.5 7.1 6.0 5.8 3.8 9.0 13.5 4.9 0.0 1.7 2.6 21.7 50.9 13.5 13.6 25.6 6.0 42.4 18.7 4.7 14.3 19.2 3.7 20.9 2.8 39.0 3.1 0.0 35.9 61.1 57.9 6.6 6.7 43.9 2.5 0.3 9.1 3.7 7.9 4.6 53.7 133.5 0.2 1.8 53.6 22.3 1.7 30.9 17.7 69.2 9.7 46.9 7.1 24.8 26.0 23.2 2.8 14.1 14.3 17.5 17.1 50.5 26.2 0.8 12.8 9.9 11.0 0.4 1.1 18.5 34.2 0.0 33.7 5.3 9.7 3.2 16.7 41.3 3.4 47.0 28.7 3.6 16.5 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 DUX4 ENSG00000260596 "Double homeobox 4" Q9UBX2 4 190173774-190185942 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Group enriched" "Detected in some" 26 "Early spermatids: 4.9;Late spermatids: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.5;U-2 OS: 2.2;U-266/70: 4.7;U-266/84: 6.9;U-698: 1.5" "Low region specificity" "Detected in some" HPA058451 Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli" "Golgi apparatus, Cytosol" "HPA058451: AB_2683722" 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.4 0.0 4.7 6.9 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DVL3 KIAA0208 ENSG00000161202 "Dishevelled segment polarity protein 3" Q92997 3 184155377-184173614 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046486, HPA058265" Approved Approved "Intermediate filaments,Midbody ring,Centrosome" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Midbody ring, Centrosome" "Intermediate filaments" "CAB046486: AB_10610845, HPA058265: AB_2683658" "unprognostic (2.20e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.88e-2)" "unprognostic (1.64e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (8.61e-2)" "unprognostic (5.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (4.77e-5)" "prognostic unfavorable (1.53e-8)" "unprognostic (1.87e-1)" "unprognostic (4.10e-1)" "unprognostic (8.41e-2)" "unprognostic (3.95e-1)" 35.2 28.1 16.4 18.7 17.4 18.6 29.8 17.4 18.9 39.0 15.9 46.0 17.2 44.7 16.1 30.3 34.5 22.6 35.0 16.4 17.1 25.7 20.0 31.7 13.9 18.1 17.3 42.0 25.6 17.9 24.4 38.3 17.6 29.1 16.1 22.8 25.6 25.8 34.9 33.8 27.1 31.7 16.6 25.6 27.9 15.1 17.0 12.4 30.0 22.3 15.9 36.6 31.6 18.3 47.9 13.6 36.4 41.4 37.5 37.8 95.0 28.4 28.9 32.7 27.6 43.6 18.3 33.6 73.3 37.0 32.4 40.8 29.6 22.2 23.4 54.0 32.2 38.1 21.3 28.2 56.6 21.2 27.8 38.4 39.9 23.4 27.3 55.9 24.6 21.6 38.9 44.2 35.5 46.5 28.3 25.2 32.8 34.6 22.1 49.9 42.7 30.0 31.7 36.2 36.3 51.0 34.9 39.8 67.4 35.8 98.7 26.8 25.0 29.5 28.5 31.0 43.8 48.3 38.8 37.0 30.0 22.4 23.6 0.1 0.6 1.3 0.6 1.0 0.8 0.7 0.4 0.7 0.6 0.5 0.5 0.3 0.9 0.4 0.3 0.8 0.2 0.4 16.4 17.4 17.4 18.9 16.4 17.1 18.1 17.3 17.6 16.6 17.0 18.3 15.9 25.6 14.1 16.6 10.8 18.7 15.7 12.9 15.9 20.1 23.5 16.5 26.9 12.8 17.2 22.0 27.1 34.4 14.6 40.8 23.5 13.3 12.8 23.2 30.9 15.9 34.3 6.9 11.4 16.6 21.6 22.6 32.6 27.7 17.1 29.7 19.2 20.5 20.3 62.2 11.8 22.3 12.2 16.2 14.4 47.5 33.5 17.4 12.4 14.0 10.8 19.7 14.4 9.0 11.5 20.7 18.9 37.2 13.9 20.8 25.2 18.3 13.4 18.5 19.7 23.6 27.1 10.6 12.4 20.4 21.7 52.1 10.3 21.9 21.5 25.7 DXO DOM3Z ENSG00000204348 "Decapping exoribonuclease" O77932 6 31969810-31972290 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 467.9;Late spermatids: 242.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046708 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA046708: AB_2679764" "unprognostic (4.56e-2)" "unprognostic (2.21e-1)" "unprognostic (1.80e-1)" "unprognostic (4.07e-3)" "unprognostic (1.93e-1)" "unprognostic (2.00e-3)" "unprognostic (3.43e-3)" "unprognostic (4.18e-3)" "unprognostic (3.10e-2)" "unprognostic (2.64e-3)" "prognostic favorable (5.87e-4)" "unprognostic (4.29e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (9.17e-2)" "unprognostic (7.24e-2)" "unprognostic (2.01e-1)" "unprognostic (2.23e-3)" 6.6 17.8 8.2 3.9 8.1 1.4 6.9 8.2 8.5 10.7 9.6 7.1 4.5 8.1 5.8 5.7 8.5 4.2 9.6 8.1 8.4 12.3 13.0 6.4 4.6 9.3 8.6 13.4 10.8 11.8 13.0 4.4 8.7 10.3 3.9 4.8 6.7 6.0 5.3 4.9 5.8 4.8 8.6 9.7 8.6 31.3 8.3 7.0 11.5 7.1 3.0 7.9 7.4 8.5 12.9 6.3 5.8 23.1 9.5 6.4 6.7 7.5 12.0 16.2 15.5 7.6 5.9 5.2 8.5 16.6 5.2 8.7 10.1 16.8 9.4 9.6 12.9 9.3 15.8 16.4 18.7 0.0 4.6 9.7 16.3 10.5 13.5 9.9 21.3 6.6 8.3 11.9 9.8 14.7 1.5 11.1 4.4 8.4 1.3 4.0 4.1 8.2 21.2 4.5 30.1 17.0 6.6 7.3 16.9 4.1 0.0 14.8 7.0 4.7 12.6 4.6 12.3 9.1 9.4 10.2 4.6 14.4 5.2 0.0 1.9 1.0 2.2 1.6 3.9 2.4 2.3 1.4 4.3 2.1 1.6 2.3 0.3 2.1 1.4 1.3 1.6 1.8 8.2 8.1 8.2 8.5 8.1 8.4 9.3 8.6 8.7 8.6 8.3 8.5 11.2 6.4 9.6 11.8 16.8 8.5 15.3 14.3 19.9 13.3 13.6 11.4 7.1 11.5 10.5 3.7 16.7 14.5 14.1 5.0 19.6 8.4 467.9 9.3 10.6 9.8 16.2 4.4 4.4 12.6 9.5 10.9 15.8 8.7 6.3 12.1 8.6 10.9 6.6 5.0 6.2 9.0 12.2 5.9 4.9 242.8 17.7 6.9 12.4 1.9 4.3 16.0 11.3 7.5 6.6 6.9 10.5 12.4 14.7 10.8 10.6 13.3 8.9 15.6 13.1 7.1 14.3 78.4 16.1 11.8 5.5 20.1 15.4 22.6 8.3 11.5 DYNC1I2 "DIC74, DNCI2" ENSG00000077380 "Dynein cytoplasmic 1 intermediate chain 2" Q13409 2 171687409-171750158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transport" "Motor protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033836, HPA040619, HPA053987" Supported Supported "Nucleoli,Endoplasmic reticulum,Microtubules,Cytosol" NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Cytosol" "Nucleoli, Microtubules" "CAB033836: AB_2093633, HPA040619: AB_2677045, HPA053987: AB_2682334" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-2)" "unprognostic (8.15e-2)" "unprognostic (8.90e-2)" "unprognostic (1.37e-3)" "unprognostic (2.51e-3)" "unprognostic (6.30e-3)" "unprognostic (1.23e-1)" "unprognostic (1.89e-2)" "unprognostic (1.40e-2)" "unprognostic (4.19e-1)" "prognostic favorable (8.04e-4)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (1.35e-3)" "unprognostic (6.42e-2)" 65.1 58.5 89.2 44.4 121.1 23.1 65.3 122.6 185.9 62.3 70.4 62.3 54.3 74.5 51.0 68.3 47.1 58.6 65.9 89.2 101.4 80.0 41.3 51.7 38.7 130.5 116.2 71.7 38.7 68.2 29.4 76.2 124.1 59.9 64.7 63.5 46.7 60.3 51.0 48.8 51.0 80.4 104.0 41.4 49.3 55.9 112.9 60.0 56.3 57.7 47.4 72.3 53.3 155.5 87.5 55.0 167.0 61.9 151.2 144.0 94.2 149.2 115.7 122.9 133.7 96.5 84.4 79.2 127.7 178.8 168.0 86.2 132.5 143.5 159.8 30.1 59.7 69.3 65.7 109.6 75.5 80.0 71.7 113.0 133.4 152.3 97.3 171.7 219.1 76.5 112.1 21.3 246.1 54.4 68.9 65.7 77.0 127.0 55.5 68.7 149.8 58.3 163.3 138.0 105.8 116.6 82.7 65.6 90.6 126.0 64.1 77.3 238.3 185.9 91.9 75.2 90.9 26.3 54.0 64.5 126.8 64.2 139.2 209.6 93.9 49.2 50.7 98.0 54.3 77.2 58.1 59.4 68.7 71.1 51.7 49.5 5.8 64.4 100.1 111.8 66.2 39.6 89.2 121.1 122.6 185.9 89.2 101.4 130.5 116.2 124.1 104.0 112.9 155.5 146.2 198.7 60.6 30.3 49.2 50.6 59.2 138.5 19.9 73.1 101.7 87.1 75.4 158.7 124.8 169.2 64.6 101.9 46.3 169.5 131.0 207.6 129.5 118.2 147.3 117.1 84.3 95.2 102.4 161.5 107.5 91.2 42.8 172.6 102.3 69.3 174.9 150.7 101.1 80.8 104.9 140.0 116.0 148.1 39.8 48.0 128.6 75.9 35.6 45.9 156.2 91.3 70.0 35.7 182.4 189.2 126.9 138.0 22.7 44.7 139.2 270.3 108.0 128.9 111.7 61.4 111.0 248.4 95.2 43.2 60.0 115.6 46.7 60.6 123.9 58.5 DYNC2H1 "DHC1b, DHC2, DNCH2, DYH1B, hdhc11" ENSG00000187240 "Dynein cytoplasmic 2 heavy chain 1" Q8NCM8 11 103109410-103479863 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Cone photoreceptor cells: 112.6;Endometrial ciliated cells: 124.0;Excitatory neurons: 164.7;Inhibitory neurons: 101.8;Respiratory ciliated cells: 171.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039015, HPA039016" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Cytosol" "HPA039015: AB_2676309, HPA039016: AB_10673410" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (1.28e-2)" "unprognostic (1.54e-1)" "unprognostic (7.11e-2)" "unprognostic (2.08e-1)" "unprognostic (4.14e-3)" "unprognostic (2.07e-2)" "unprognostic (2.05e-1)" "unprognostic (4.10e-2)" "unprognostic (2.87e-2)" "unprognostic (7.13e-2)" "prognostic favorable (8.49e-5)" "unprognostic (3.75e-3)" "unprognostic (1.62e-1)" "unprognostic (3.88e-2)" "unprognostic (4.11e-3)" 4.2 3.0 5.0 1.2 5.2 0.3 3.5 5.6 10.2 5.1 14.6 3.2 1.6 4.6 3.7 1.6 6.5 3.2 2.0 4.1 6.1 3.7 0.8 2.8 0.9 8.3 8.9 5.6 2.9 6.7 6.8 1.4 6.3 2.6 0.7 10.5 2.6 2.5 0.8 2.8 2.1 2.3 5.5 1.9 2.2 7.9 6.7 1.8 4.6 1.5 0.7 3.3 3.0 5.9 1.3 2.7 7.0 3.3 9.5 21.2 0.4 4.0 6.4 6.5 7.0 1.6 1.5 0.0 5.5 8.0 3.1 5.5 5.5 7.7 5.3 0.0 4.6 1.2 4.8 0.2 9.3 2.2 1.3 13.6 2.8 14.9 16.9 10.3 2.7 1.4 0.2 0.0 8.6 5.4 0.7 0.7 1.9 0.0 7.7 0.0 5.9 0.1 7.5 0.9 4.6 3.6 6.5 1.7 3.1 1.7 6.8 1.5 6.4 7.9 3.3 7.7 3.0 0.0 0.0 0.1 2.3 6.7 2.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 5.0 5.2 5.6 10.2 4.1 6.1 8.3 8.9 6.3 5.5 6.7 5.9 12.7 0.0 13.1 173.7 2.3 6.6 13.4 17.3 9.6 25.9 8.2 9.7 10.1 4.3 18.0 27.6 112.6 0.3 2.1 0.2 1.9 7.0 26.1 124.0 43.7 11.1 17.3 1.3 164.7 3.4 0.5 32.0 5.6 7.5 3.8 15.4 9.3 0.8 2.5 32.0 101.8 1.0 4.1 0.8 5.8 11.1 20.8 3.1 8.8 45.0 0.9 16.5 1.0 86.0 72.6 10.5 2.9 18.4 3.3 4.9 0.9 16.9 171.0 85.1 19.7 40.8 18.5 90.6 11.6 5.0 5.5 0.5 5.0 23.5 1.7 5.9 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4098.6;Respiratory ciliated cells: 2679.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA Yes 890000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 268.6 261.9 912.5 186.7 967.7 126.8 268.0 895.2 1292.9 354.2 894.7 325.8 162.8 319.4 322.3 719.9 544.2 242.7 257.5 975.4 944.7 352.6 238.4 222.6 241.6 896.1 898.5 247.0 225.1 228.2 309.7 259.2 914.2 225.9 327.4 181.3 245.4 264.6 85.6 626.7 206.3 390.1 935.1 185.2 244.5 360.3 909.7 306.5 176.1 163.9 357.8 389.8 474.4 1001.2 721.6 811.4 779.2 600.8 677.1 713.6 250.8 968.0 451.6 785.6 466.7 770.8 472.3 400.6 510.3 945.1 753.0 629.6 949.3 818.3 781.0 528.3 617.9 390.4 532.9 1062.5 676.2 412.8 620.5 436.2 863.0 584.6 477.5 855.7 831.8 421.5 502.0 446.1 1056.8 960.1 541.4 894.8 642.2 917.7 935.7 543.0 403.0 499.2 1143.1 659.8 535.2 392.0 789.3 677.7 926.6 812.6 673.6 595.3 635.2 592.3 502.1 525.6 852.2 264.0 562.8 404.6 656.8 645.1 776.6 516.6 291.9 384.2 200.6 303.3 155.3 310.4 207.2 211.7 281.8 219.0 132.0 165.7 50.1 282.9 334.8 461.6 373.5 353.0 912.5 967.7 895.2 1292.9 975.4 944.7 896.1 898.5 914.2 935.1 909.7 1001.2 810.1 195.5 101.9 79.3 341.4 922.2 359.1 1275.0 356.8 138.4 800.0 949.4 170.8 303.1 764.6 399.1 83.4 524.6 484.1 689.9 1113.2 691.2 1407.2 1842.5 528.5 541.9 480.8 332.9 111.2 538.9 897.4 538.5 240.5 488.1 316.7 611.9 521.9 499.0 732.1 85.8 62.8 801.6 1121.0 329.4 706.1 4098.6 516.6 466.3 595.9 42.2 701.6 164.0 248.2 47.3 156.4 754.9 798.6 701.8 234.9 304.7 533.4 1125.0 2679.6 193.5 368.1 440.7 1016.3 961.5 721.4 1005.4 1610.1 1006.6 396.6 586.3 498.2 389.6 DYNLL2 "Dlc2, DNCL1B, MGC17810, RSPH22" ENSG00000264364 "Dynein light chain LC8-type 2" Q96FJ2 17 58083419-58095542 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 455.4;Late spermatids: 892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 1000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (7.22e-2)" "unprognostic (7.76e-2)" "unprognostic (3.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.93e-1)" "unprognostic (3.72e-2)" "unprognostic (6.78e-2)" "unprognostic (2.91e-2)" "unprognostic (1.68e-1)" "unprognostic (1.10e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.24e-1)" "prognostic favorable (1.12e-12)" "unprognostic (2.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.31e-1)" "unprognostic (7.02e-2)" 24.5 41.8 76.8 17.7 84.5 17.7 16.9 78.1 77.7 18.2 45.6 26.1 25.0 19.6 22.4 20.3 19.4 13.4 62.8 63.4 80.4 42.1 35.2 17.9 15.5 83.6 90.1 20.4 17.8 47.2 28.7 30.4 83.6 30.3 20.1 41.2 30.8 26.3 113.7 19.1 24.3 18.9 83.4 18.0 21.3 26.2 87.9 22.5 33.0 58.7 18.4 20.7 17.6 72.0 54.1 36.0 72.3 33.1 44.0 24.0 114.6 53.2 21.1 25.2 19.7 80.4 25.4 48.0 58.8 33.1 30.1 28.4 33.8 42.2 43.2 47.8 24.5 52.1 21.9 47.7 34.8 56.2 31.1 24.3 28.2 29.4 23.2 26.4 17.1 39.8 52.7 28.4 24.7 81.5 64.1 23.2 49.9 35.3 36.5 58.3 42.5 19.9 22.0 57.9 49.3 39.4 47.7 19.0 42.0 37.2 56.2 26.1 31.0 49.3 62.2 33.2 39.8 52.6 68.5 57.0 25.5 44.2 35.2 1.0 0.2 0.5 0.6 0.1 0.7 0.4 0.5 0.6 0.1 0.4 0.5 0.8 0.4 0.4 0.9 0.2 0.4 0.2 76.8 84.5 78.1 77.7 63.4 80.4 83.6 90.1 83.6 83.4 87.9 72.0 33.9 12.8 43.8 1.0 28.1 49.1 40.7 13.7 45.5 63.7 55.7 39.8 186.2 44.3 23.8 60.7 39.6 102.1 59.7 56.7 31.3 37.6 455.4 51.5 57.3 32.5 67.2 40.6 1.2 31.2 73.4 30.6 20.9 55.2 22.8 19.1 23.9 104.7 43.0 70.7 2.0 55.7 26.4 28.4 37.4 892.8 29.5 32.8 65.8 1.9 31.9 74.7 19.6 0.5 2.8 38.0 38.6 26.7 19.4 35.3 50.0 78.2 18.4 41.1 26.3 40.1 86.1 46.5 44.8 45.1 46.0 60.1 46.9 29.0 49.7 36.5 DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 58.8;Respiratory ciliated cells: 74.0;Rod photoreceptor cells: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030404 Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA030404: AB_10601548" "unprognostic (3.65e-2)" "unprognostic (8.37e-2)" "unprognostic (2.87e-2)" "unprognostic (3.71e-2)" "unprognostic (8.22e-2)" "unprognostic (6.50e-2)" "unprognostic (6.47e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (2.35e-3)" "unprognostic (2.72e-1)" "unprognostic (9.98e-2)" "unprognostic (2.77e-2)" 4.9 1.4 1.7 2.2 2.2 8.8 4.7 5.9 2.1 8.6 15.3 5.0 2.2 8.1 1.9 2.5 12.8 5.7 3.3 2.2 2.3 5.6 1.0 5.7 0.9 5.7 7.4 7.0 6.3 2.7 2.1 2.0 4.2 4.1 1.5 4.6 2.1 3.3 1.0 7.8 2.1 4.6 4.3 2.6 7.2 4.1 2.6 0.4 3.6 0.9 0.7 6.1 5.3 2.2 5.4 3.1 6.1 5.1 3.8 5.1 1.4 8.6 5.1 5.0 6.3 2.0 0.4 0.0 4.3 8.0 7.0 1.7 4.5 2.0 2.4 1.2 4.4 2.4 7.5 0.3 3.1 1.8 4.0 5.4 2.0 5.5 2.6 5.1 2.8 1.4 1.8 0.0 6.9 0.3 0.0 0.8 7.4 0.0 1.1 0.0 7.1 0.0 2.3 8.5 2.1 4.8 8.9 0.0 4.3 3.4 2.3 3.7 2.2 12.3 5.6 6.0 4.5 0.0 0.0 0.1 4.9 2.6 4.8 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 2.2 5.9 2.1 2.2 2.3 5.7 7.4 4.2 4.3 2.6 2.2 1.4 3.2 2.0 4.2 0.0 3.6 0.6 1.9 7.4 8.6 0.2 2.5 2.9 7.2 7.7 1.8 8.4 0.1 0.0 0.0 5.9 3.8 17.4 58.8 8.5 2.6 0.0 1.3 4.0 1.2 0.1 6.5 7.1 1.1 0.0 7.4 0.0 0.0 1.4 3.3 2.9 0.0 2.0 3.2 2.6 1.8 6.2 3.5 0.0 3.7 0.6 2.7 0.0 2.5 0.2 5.9 0.0 4.1 0.0 0.4 0.0 0.8 74.0 19.4 0.0 7.2 9.8 0.6 2.3 1.7 4.3 0.0 0.5 1.7 0.0 0.1 E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029779, HPA065012" Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA029779: AB_2732448, HPA065012: AB_2685403" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (2.96e-1)" "unprognostic (9.14e-2)" "unprognostic (8.99e-3)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (3.50e-1)" "unprognostic (5.99e-3)" 6.5 4.9 4.8 9.8 5.2 19.8 4.1 2.8 5.7 3.3 3.0 5.4 5.2 3.6 3.9 4.9 2.5 6.4 5.1 6.4 4.6 5.8 4.4 4.9 11.0 3.7 4.6 1.4 2.1 3.1 1.8 5.6 4.2 3.3 6.3 6.1 2.7 3.1 10.0 2.6 5.7 6.0 3.7 8.4 3.6 3.4 5.5 8.6 8.5 9.3 9.5 8.5 2.7 3.8 14.3 11.6 32.2 35.1 10.9 11.9 22.0 18.9 16.8 18.2 19.9 14.3 8.8 32.3 35.2 18.2 16.9 14.6 37.8 17.4 30.3 12.2 25.3 58.1 20.4 16.3 11.6 38.6 33.0 9.7 12.6 17.7 21.6 18.8 12.7 29.8 65.3 19.4 20.9 15.0 43.6 43.2 24.2 11.0 11.9 46.5 27.8 36.5 21.8 25.1 22.9 42.2 17.3 24.1 26.3 20.0 12.4 23.4 17.2 28.6 17.4 14.2 30.5 12.1 40.1 38.3 7.1 23.2 41.3 5.6 2.3 1.1 1.6 1.6 2.0 0.4 1.0 2.4 2.6 0.4 0.8 1.8 7.2 3.5 1.1 1.1 1.6 1.1 4.8 5.2 2.8 5.7 6.4 4.6 3.7 4.6 4.2 3.7 5.5 3.8 4.8 0.0 2.6 53.8 10.6 9.2 12.3 7.0 7.4 34.1 11.9 7.2 10.6 4.3 10.6 7.3 22.9 8.3 15.0 12.0 9.8 7.6 12.2 3.9 14.1 8.5 12.0 17.2 67.7 6.9 13.8 9.2 12.8 10.6 20.3 32.3 14.6 4.7 17.1 32.0 31.9 11.7 4.1 47.2 17.7 5.7 2.8 28.7 5.4 27.2 23.8 2.9 15.5 37.7 2.9 14.8 10.3 3.0 19.1 22.1 4.5 25.1 2.2 9.0 0.0 9.0 11.5 3.0 4.7 16.5 8.9 3.1 15.3 5.7 13.8 18.4 E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.6" "Cell type enhanced" "Detected in many" "B-cells: 23.7;Plasma cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.4;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.4" "Cell line enhanced" "Detected in many" "AF22: 82.6;Daudi: 158.0;U-698: 77.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli, Vesicles" "HPA055723: AB_2682897, HPA065441: " "unprognostic (8.73e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.73e-3)" "unprognostic (1.62e-1)" "unprognostic (3.36e-5)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (2.88e-2)" "unprognostic (3.25e-2)" "unprognostic (3.64e-1)" "unprognostic (2.95e-3)" 1.8 3.9 4.8 8.0 5.2 1.7 6.7 4.6 6.5 5.2 5.1 6.6 4.9 4.5 8.1 2.2 8.0 4.3 1.9 5.1 5.8 8.1 3.0 4.1 25.9 5.5 5.2 4.9 4.3 13.2 3.7 5.0 5.0 3.6 7.8 0.9 2.3 3.3 0.4 0.8 3.8 4.1 5.1 6.9 5.5 8.5 5.3 10.7 8.7 0.9 29.6 6.9 0.9 5.5 14.2 15.9 82.6 29.7 1.5 2.2 25.0 2.7 6.9 2.4 7.4 9.6 17.4 158.0 10.3 3.5 28.4 2.6 51.0 4.3 3.0 16.0 20.1 16.4 8.3 22.4 13.4 4.8 0.1 3.3 6.9 3.5 12.0 15.7 2.7 16.5 34.7 1.2 4.6 10.0 15.8 10.8 26.1 28.0 12.9 12.9 3.4 17.9 27.5 10.7 9.8 29.8 1.8 5.8 23.8 32.6 33.5 5.2 0.1 3.7 2.5 4.6 10.5 27.6 20.6 77.1 4.3 4.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 13.4 0.0 0.0 0.1 8.9 0.2 0.4 0.0 1.4 0.0 1.5 0.6 0.6 4.8 5.2 4.6 6.5 5.1 5.8 5.5 5.2 5.0 5.1 5.3 5.5 1.1 0.0 6.5 3.6 23.7 2.3 3.3 1.3 1.2 0.9 5.6 6.0 1.0 5.7 2.9 5.5 10.4 4.1 5.1 3.3 0.0 3.3 7.6 7.3 5.2 1.5 7.8 1.3 7.7 2.6 1.1 3.0 4.1 7.5 1.3 5.5 0.4 2.4 0.5 0.0 4.6 2.7 2.0 0.8 1.0 3.8 1.5 1.9 3.6 4.7 0.3 5.2 4.1 11.6 4.2 3.0 1.7 1.9 29.6 6.9 0.8 5.8 8.6 1.6 0.0 5.0 4.5 8.1 4.6 2.3 2.8 1.1 2.5 4.6 3.7 2.1 E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;lymphoid tissue: 11.8;skeletal muscle: 12.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 34.1;Gastric mucus-secreting cells: 10.2;Plasma cells: 9.7;Squamous epithelial cells: 10.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytosol" "HPA064882: AB_2685381, HPA076614: " "unprognostic (5.62e-2)" "unprognostic (5.24e-2)" "unprognostic (3.17e-2)" "unprognostic (6.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (1.29e-5)" "unprognostic (1.94e-2)" "unprognostic (3.90e-3)" "unprognostic (2.41e-1)" "unprognostic (7.29e-4)" "unprognostic (1.16e-2)" "unprognostic (9.13e-8)" "unprognostic (1.02e-3)" "unprognostic (1.37e-1)" "unprognostic (3.81e-1)" "unprognostic (4.28e-3)" 0.3 0.1 0.0 2.8 0.0 14.2 0.5 0.1 0.1 1.0 0.0 4.0 3.8 0.4 0.0 4.9 0.9 0.4 2.1 0.0 0.0 0.1 0.3 0.3 7.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 5.1 0.0 0.9 0.2 12.6 3.0 3.0 0.6 0.0 1.3 5.6 1.7 0.0 11.8 0.1 0.4 7.3 1.8 1.3 0.1 23.3 7.2 7.1 9.8 0.4 1.1 31.7 13.0 3.7 15.3 16.4 25.4 7.8 23.5 5.5 4.3 9.0 20.2 17.2 1.6 13.5 15.9 14.9 8.0 4.1 7.1 0.0 12.7 19.2 0.3 0.1 3.1 1.0 0.9 21.0 17.2 17.6 22.1 6.3 11.6 25.8 16.6 6.9 26.3 10.1 26.9 12.8 16.0 6.6 16.8 6.0 7.0 5.5 11.3 1.3 4.0 7.7 13.7 4.2 7.3 9.0 18.3 11.8 7.7 16.2 30.6 9.0 24.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.1 0.1 1.3 0.0 0.0 0.3 0.1 3.8 0.0 0.5 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.4 3.3 0.8 0.8 1.2 34.1 0.1 0.0 1.7 1.0 10.2 3.3 0.0 3.1 0.0 0.0 2.4 0.0 0.0 3.9 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 1.2 0.0 9.7 0.1 0.4 0.2 5.6 0.0 0.0 1.5 0.9 4.0 3.1 10.0 0.3 0.3 2.2 0.5 6.3 0.9 EAF1 ENSG00000144597 "ELL associated factor 1" Q96JC9 3 15427598-15450635 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.1" "Group enriched" "Detected in all" 6 "Early spermatids: 268.7;Late spermatids: 389.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 137.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059516, HPA060569, HPA069538" Supported Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA No "Cluster 16: MAIT-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" Vesicles "HPA059516: AB_2684048, HPA060569: AB_2684322, HPA069538: AB_2686147" "unprognostic (1.26e-1)" "unprognostic (1.61e-2)" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (3.22e-1)" "unprognostic (3.16e-2)" "unprognostic (3.22e-1)" "unprognostic (8.45e-2)" "unprognostic (2.06e-2)" "unprognostic (5.17e-2)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (1.64e-1)" 12.9 9.0 9.2 10.5 8.9 57.1 9.1 7.2 9.4 7.2 7.7 9.0 10.6 7.9 7.6 9.8 7.0 10.4 5.1 10.3 11.1 11.2 19.0 8.3 10.7 9.6 10.3 5.6 9.8 11.8 8.6 10.2 12.3 10.0 9.9 7.7 6.9 6.8 5.3 10.7 10.0 8.3 7.8 9.8 11.4 7.3 10.6 10.6 10.5 5.8 11.1 11.5 5.8 7.9 10.3 16.6 17.1 17.6 9.8 8.3 137.4 14.7 10.5 16.7 16.3 22.7 11.4 28.7 9.3 10.9 10.9 8.6 22.5 13.2 19.2 23.6 16.2 24.8 14.5 20.8 22.1 23.6 19.2 11.0 22.8 24.3 16.2 12.8 16.8 23.1 26.9 20.6 14.1 21.2 23.6 13.2 30.7 19.3 16.9 21.3 14.2 16.0 14.5 17.8 17.6 30.6 18.2 16.7 17.6 21.9 25.2 18.5 16.6 17.5 12.8 15.6 21.8 27.1 58.3 29.7 17.0 27.7 21.1 8.0 7.1 4.6 11.1 5.4 14.3 4.9 9.1 8.7 4.2 3.6 5.4 8.7 6.5 8.1 6.9 9.8 10.9 4.4 9.2 8.9 7.2 9.4 10.3 11.1 9.6 10.3 12.3 7.8 10.6 7.9 11.5 9.6 17.3 6.8 14.2 46.9 9.1 6.0 14.2 8.1 15.8 7.7 4.8 15.7 9.0 12.9 6.2 8.0 29.1 15.5 9.8 8.6 268.7 10.8 16.0 11.8 34.3 7.8 16.4 8.2 14.6 13.9 16.3 14.1 10.2 9.9 12.1 30.4 15.8 21.9 14.0 12.5 12.2 30.7 31.6 389.5 11.5 37.6 23.2 3.7 19.4 5.5 22.6 5.5 10.7 15.6 10.3 12.0 12.2 16.1 16.0 29.7 8.6 6.4 26.3 13.6 11.0 21.5 11.6 17.7 54.3 35.8 22.0 4.3 12.8 19.9 EAPP "BM036, C14orf11, FLJ20578" ENSG00000129518 "E2F associated phosphoprotein" Q56P03 14 34515938-34539711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002916 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA002916: AB_1078715" "unprognostic (8.76e-3)" "unprognostic (1.27e-3)" "unprognostic (2.08e-3)" "unprognostic (1.94e-1)" "unprognostic (4.59e-2)" "unprognostic (1.64e-1)" "unprognostic (2.80e-1)" "prognostic favorable (9.34e-4)" "unprognostic (1.81e-1)" "unprognostic (6.38e-2)" "unprognostic (2.05e-1)" "unprognostic (7.80e-2)" "prognostic favorable (2.23e-6)" "unprognostic (2.64e-1)" "unprognostic (2.68e-1)" "prognostic favorable (2.96e-4)" "unprognostic (3.24e-2)" 37.3 35.8 26.3 24.6 27.0 89.2 51.0 29.7 35.5 33.3 27.1 50.8 35.7 35.0 44.7 29.0 39.4 28.1 29.0 27.1 28.6 42.4 50.2 29.5 37.2 25.9 26.5 49.7 26.7 54.7 21.6 35.2 26.3 33.7 51.7 37.1 36.4 31.2 37.0 46.9 45.6 29.2 28.1 31.3 29.3 23.5 27.1 49.1 45.5 29.3 37.1 31.1 30.0 30.0 37.7 45.1 41.3 24.4 47.8 48.7 64.1 33.8 51.6 41.5 43.1 21.6 48.6 39.1 46.6 41.5 24.7 34.5 30.8 45.1 48.3 49.1 27.1 28.7 31.6 91.7 65.1 51.5 30.4 56.3 56.7 23.8 60.9 54.6 41.7 54.1 28.9 42.0 39.1 88.0 71.4 41.5 24.3 69.4 50.0 44.8 49.5 39.5 50.2 50.3 33.1 36.5 47.8 45.6 76.4 39.4 79.7 32.3 45.2 21.4 18.1 28.1 22.0 52.8 63.1 41.5 20.1 28.0 27.6 139.9 61.9 134.3 65.3 57.8 79.1 107.7 81.9 75.0 54.9 101.0 82.7 75.8 140.2 100.6 80.9 47.8 124.4 80.0 26.3 27.0 29.7 35.5 27.1 28.6 25.9 26.5 26.3 28.1 27.1 30.0 59.8 22.4 53.3 17.0 78.6 46.4 67.2 145.0 74.6 75.6 60.0 70.1 35.4 60.1 78.8 82.8 31.3 125.3 76.3 91.8 174.1 86.6 20.9 82.0 59.6 57.8 66.0 66.7 20.5 84.5 76.5 67.6 26.5 54.8 73.5 98.7 57.5 109.0 58.8 25.2 21.3 112.8 87.5 50.6 33.9 14.9 89.5 47.5 90.7 16.9 71.3 122.0 87.6 17.6 23.1 59.8 102.5 94.4 46.8 61.4 131.5 164.8 102.0 75.7 72.3 69.9 78.7 103.3 38.3 63.8 66.5 189.4 74.2 101.2 98.0 58.2 EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 38000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: AB_1847954, HPA028277: AB_10603664" "unprognostic (9.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.03e-2)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (7.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.24e-3)" "unprognostic (7.11e-2)" "unprognostic (1.64e-3)" "unprognostic (4.10e-3)" "unprognostic (3.04e-3)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-2)" 35.1 38.8 30.3 35.2 31.1 34.3 39.5 28.8 33.5 30.0 32.5 35.4 23.6 35.5 55.7 46.5 43.5 21.7 37.1 31.1 31.0 55.7 126.6 27.7 35.9 29.3 28.5 27.3 36.1 45.6 48.9 33.1 30.0 29.0 36.5 19.6 34.5 31.0 51.9 36.8 24.5 35.0 29.6 24.8 33.4 44.4 31.8 30.5 41.4 28.6 39.8 52.5 34.5 31.1 325.0 180.2 66.0 192.7 52.1 58.3 142.6 219.4 107.8 338.7 210.5 215.2 192.5 211.0 167.9 157.0 157.2 218.2 144.5 200.9 360.5 101.2 146.5 144.8 160.9 188.5 95.7 248.7 106.8 47.6 197.4 248.6 197.3 64.2 185.5 145.2 220.3 67.8 165.1 172.8 190.0 152.0 290.8 209.5 165.0 139.2 150.4 235.5 123.7 135.0 132.0 139.9 127.3 228.6 219.0 105.6 94.5 136.1 147.6 128.7 248.9 211.4 360.7 102.9 219.7 262.7 107.6 258.7 265.2 19.7 45.4 24.9 52.3 54.1 55.2 61.5 52.8 54.5 68.7 68.5 48.3 48.3 3.9 59.6 53.3 65.6 60.5 43.6 30.3 31.1 28.8 33.5 31.1 31.0 29.3 28.5 30.0 29.6 31.8 31.1 38.0 35.3 39.5 5.9 36.9 123.0 91.6 78.0 40.5 26.3 50.6 62.1 32.0 52.9 52.5 31.3 6.2 102.2 23.3 34.0 90.1 144.5 163.5 56.8 47.3 51.0 24.1 45.0 5.6 124.4 135.1 51.5 33.1 31.6 50.7 35.1 27.8 148.3 63.3 15.2 3.8 49.7 48.8 22.5 24.7 94.9 33.2 28.9 55.2 3.7 41.4 55.7 35.0 6.0 4.9 135.3 25.8 38.4 53.1 179.3 29.4 135.9 81.3 29.5 39.5 55.0 68.1 92.6 97.8 54.2 99.4 84.3 26.8 57.8 66.2 95.3 ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 106.9;ovary: 99.7;pituitary gland: 27.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 33.5;Muller glia cells: 100.3;Peritubular cells: 21.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.9" "Region enhanced" "Detected in many" "hypothalamus: 106.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AN3-CA: 44.1;HeLa: 21.8" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Approved "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (1.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.39e-1)" "unprognostic (4.62e-3)" "unprognostic (2.80e-1)" "unprognostic (9.96e-4)" "unprognostic (7.56e-3)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.49e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.24e-5)" "unprognostic (3.09e-2)" "unprognostic (3.68e-1)" "unprognostic (7.84e-2)" "unprognostic (5.45e-2)" 1.8 10.0 5.2 1.0 5.5 0.0 1.7 1.2 31.6 1.0 3.4 0.8 0.1 2.2 0.0 0.4 3.5 0.5 0.2 0.5 106.9 4.1 2.5 0.4 0.3 20.9 11.3 99.7 0.7 1.2 27.6 0.3 17.1 0.4 0.0 13.4 0.6 1.5 3.0 0.6 0.4 1.4 2.4 4.5 0.9 1.9 44.2 0.2 1.4 0.0 0.4 0.4 1.1 4.5 0.0 0.1 0.1 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.4 0.0 0.2 0.0 0.6 0.0 0.0 0.0 4.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 3.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.5 1.2 31.6 0.5 106.9 20.9 11.3 17.1 2.4 44.2 4.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 33.5 0.5 0.3 1.1 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 1.1 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 1.5 0.1 0.0 0.0 0.0 100.3 0.0 0.0 0.0 0.1 0.0 21.1 0.0 0.0 0.0 0.1 0.0 3.7 0.0 1.0 2.3 0.5 1.6 0.0 0.0 0.0 0.1 0.6 0.0 0.1 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EDRF1 "C10orf137, DKFZp586F1019, FLJ21617" ENSG00000107938 "Erythroid differentiation regulatory factor 1" Q3B7T1 10 125719515-125764143 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031820 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Centrosome, Cytosol" "HPA031820: AB_10600753" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (1.53e-1)" "unprognostic (3.64e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-2)" "unprognostic (8.84e-4)" "unprognostic (4.76e-3)" "unprognostic (8.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.63e-3)" "unprognostic (4.62e-2)" "prognostic unfavorable (3.16e-5)" "unprognostic (3.44e-3)" "unprognostic (5.51e-2)" "unprognostic (1.38e-1)" "unprognostic (7.68e-3)" 4.1 4.0 2.0 6.1 2.7 21.8 5.6 5.3 2.9 5.6 2.7 4.0 5.0 7.4 4.9 4.7 4.6 4.1 5.1 2.9 2.0 3.6 2.8 4.2 9.7 1.7 1.7 8.0 7.2 4.3 2.9 5.7 2.3 6.8 5.2 4.6 12.3 4.1 5.7 5.1 4.5 5.2 1.5 5.4 4.7 15.1 1.7 9.4 5.2 5.1 8.2 4.4 3.3 4.1 12.6 11.7 15.4 16.5 7.2 10.0 7.8 14.8 13.6 16.3 18.5 15.7 10.4 16.5 6.9 9.6 9.5 15.3 22.6 4.7 18.0 10.3 18.3 12.0 12.5 8.9 9.6 17.0 12.1 6.5 6.0 16.2 8.1 15.6 7.8 8.9 11.1 11.2 10.6 5.3 16.9 11.8 20.6 7.7 10.2 14.0 13.2 9.7 6.5 7.2 7.6 14.9 10.7 5.9 10.1 13.9 10.3 6.8 5.4 8.8 9.6 12.4 17.1 15.0 11.4 26.1 9.3 8.8 5.0 5.9 2.3 1.4 2.7 2.0 3.4 3.1 2.2 2.5 3.0 2.3 2.2 2.8 2.9 2.9 1.3 2.9 3.1 1.4 2.0 2.7 5.3 2.9 2.9 2.0 1.7 1.7 2.3 1.5 1.7 4.1 12.4 12.8 9.7 26.1 19.1 5.9 5.7 5.1 15.4 23.9 9.3 8.4 12.9 8.6 9.0 11.0 33.3 6.7 28.5 5.1 0.0 4.3 145.1 11.2 14.6 9.5 4.2 7.6 40.9 7.2 6.0 12.1 17.3 27.2 20.3 24.7 7.5 7.0 4.1 20.2 31.7 7.5 4.1 7.7 4.2 61.5 21.1 9.2 7.2 22.5 12.2 9.1 13.4 22.1 36.2 8.3 4.9 19.9 27.1 6.6 7.1 2.7 8.6 24.4 6.6 13.0 11.0 26.8 21.4 10.6 8.2 4.5 20.1 18.5 7.3 5.2 EEF1AKMT2 "C10orf138, Efm4, METTL10" ENSG00000203791 "EEF1A lysine methyltransferase 2" Q5JPI9 10 124748149-124791887 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.1;Distal tubular cells: 66.5;Extravillous trophoblasts: 29.8;Proximal tubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA050138 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Vesicles, Cytosol" "HPA050138: AB_2681030" "unprognostic (1.64e-3)" "unprognostic (3.42e-2)" "unprognostic (1.34e-1)" "unprognostic (9.75e-2)" "unprognostic (7.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.33e-2)" "unprognostic (2.29e-3)" "unprognostic (9.04e-3)" "unprognostic (9.76e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.82e-4)" "unprognostic (3.90e-2)" "unprognostic (4.44e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.09e-2)" 4.8 3.8 3.0 2.1 3.3 3.6 5.3 4.8 4.2 4.6 3.0 3.7 1.8 4.0 4.6 4.0 3.8 2.1 4.1 3.1 3.0 4.9 5.2 3.3 2.5 2.8 3.1 5.5 4.4 4.5 4.3 2.7 2.8 4.3 3.8 2.5 5.1 2.8 4.0 5.0 3.5 2.6 2.7 3.5 3.7 5.6 2.8 3.3 5.1 3.3 3.1 3.4 4.2 3.6 12.6 3.3 4.8 8.0 3.1 8.0 3.1 5.8 7.6 7.4 6.5 4.3 7.1 8.4 3.0 4.7 2.5 3.8 6.8 4.2 11.5 7.0 2.5 6.8 4.2 3.9 6.0 10.9 4.1 3.9 3.9 4.1 9.9 6.2 4.7 7.0 7.6 9.3 9.3 3.7 5.2 8.5 5.9 4.6 4.8 2.3 5.7 2.6 4.6 2.7 1.5 3.8 3.7 6.2 8.7 3.3 5.4 8.5 5.8 2.7 2.9 4.5 8.8 4.3 3.7 6.8 4.9 5.7 3.9 0.8 1.0 1.6 1.6 1.1 2.5 1.9 1.6 2.0 1.2 1.3 2.2 1.6 0.1 4.4 0.8 1.5 1.9 1.1 3.0 3.3 4.8 4.2 3.1 3.0 2.8 3.1 2.8 2.7 2.8 3.6 23.2 3.2 11.3 0.0 8.9 0.0 0.0 0.0 0.0 0.0 20.5 22.4 0.0 0.0 2.5 11.0 0.0 29.1 13.4 0.0 66.5 20.0 0.0 11.4 11.8 7.5 0.0 0.0 0.0 20.4 29.8 10.4 0.0 10.5 2.5 17.8 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 11.4 0.0 0.0 0.0 0.0 19.8 0.0 0.0 2.8 0.0 0.0 30.5 3.6 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 17.1 7.1 14.7 0.0 0.0 EEF1AKMT3 "DKFZP586D0919, FAM119B, METTL21B" ENSG00000123427 "EEF1A lysine methyltransferase 3" Q96AZ1 12 57771492-57782541 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 14.9;Breast myoepithelial cells: 7.6;Exocrine glandular cells: 12.7;monocytes: 8.8;Proximal tubular cells: 16.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 7 "RH-30: 152.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043020, HPA045492" Uncertain Approved "Nucleoplasm,Mitotic chromosome,Centrosome" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Centrosome "Nucleoplasm, Mitotic chromosome" "HPA043020: AB_2678274, HPA045492: " "unprognostic (2.00e-1)" "unprognostic (6.52e-2)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (1.06e-1)" "unprognostic (7.34e-3)" "unprognostic (7.52e-3)" "unprognostic (1.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.54e-3)" "unprognostic (5.77e-2)" "unprognostic (1.33e-1)" "unprognostic (1.34e-2)" "unprognostic (1.23e-1)" 7.5 6.2 2.5 3.6 2.3 2.6 9.2 4.1 2.7 10.5 2.6 5.6 3.9 9.3 9.6 5.6 8.4 5.4 3.7 2.4 1.8 11.6 6.5 5.3 3.6 2.6 2.4 11.4 21.7 6.4 3.7 4.6 2.7 8.2 4.6 3.7 19.4 8.7 2.9 7.3 3.8 7.6 2.1 4.0 7.2 4.2 2.4 1.9 10.1 3.1 3.1 6.3 7.3 3.1 5.4 11.0 4.6 5.9 12.8 12.0 4.0 5.8 10.9 8.9 9.0 5.6 9.5 3.1 7.4 7.6 7.2 5.2 3.7 3.3 9.3 4.0 5.6 14.9 6.6 9.2 11.3 3.7 6.6 12.6 8.7 9.3 9.8 15.2 9.7 13.2 8.9 22.6 5.4 3.8 4.7 11.0 3.4 4.3 8.0 8.5 152.1 10.0 6.0 5.3 4.4 6.0 10.0 7.5 6.2 4.1 11.9 10.0 9.5 13.7 7.7 5.8 6.4 5.7 2.3 3.8 11.3 15.4 10.0 0.4 3.0 0.1 1.8 1.1 7.8 0.5 3.5 2.2 3.1 0.4 1.7 1.4 0.7 1.5 4.6 1.5 2.2 2.3 2.5 2.3 4.1 2.7 2.4 1.8 2.6 2.4 2.7 2.1 2.4 3.1 3.9 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 7.6 0.0 0.0 1.8 1.8 0.0 3.4 1.3 0.0 5.9 5.5 0.0 2.0 6.0 1.9 0.0 0.0 0.0 12.7 4.9 3.4 0.0 2.5 2.5 5.4 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.1 0.0 0.0 16.4 1.5 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.6 0.5 4.7 0.0 0.0 EEFSEC "EFSEC, SELB" ENSG00000132394 "Eukaryotic elongation factor, selenocysteine-tRNA specific" P57772 3 128153481-128408646 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 71.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 15.2;GAMG: 12.3;MOLT-4: 7.9;SH-SY5Y: 10.4;SK-BR-3: 17.7;SK-MEL-30: 15.4;T-47d: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035795 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA035795: AB_10696512" "unprognostic (1.01e-1)" "prognostic favorable (2.98e-5)" "unprognostic (2.53e-1)" "unprognostic (1.32e-3)" "unprognostic (1.12e-1)" "unprognostic (3.03e-1)" "unprognostic (4.37e-3)" "unprognostic (6.06e-2)" "unprognostic (6.78e-3)" "unprognostic (2.84e-1)" "unprognostic (1.61e-2)" "unprognostic (3.83e-2)" "unprognostic (1.12e-2)" "unprognostic (4.31e-2)" "unprognostic (1.99e-1)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" 13.5 8.2 0.2 0.2 0.2 0.1 12.5 0.2 0.6 14.2 0.1 11.3 0.0 15.6 0.0 12.3 13.9 0.1 25.5 0.2 0.3 14.3 21.8 9.6 2.2 0.4 0.2 12.3 11.7 3.0 8.8 1.6 0.3 12.1 0.6 0.5 9.7 1.9 24.0 16.5 10.7 0.0 0.2 13.4 11.0 19.3 0.4 0.1 9.9 0.0 1.2 12.7 12.3 0.2 0.5 0.1 4.1 1.7 0.1 0.2 0.5 0.0 0.3 0.2 0.2 0.3 6.9 15.2 0.1 3.8 12.3 1.1 0.4 0.1 0.1 0.3 0.3 0.0 0.1 0.1 5.7 0.3 0.3 0.1 0.1 4.0 0.1 0.2 0.3 0.0 0.1 0.2 3.5 0.2 7.9 0.4 0.4 0.1 0.1 0.3 0.2 1.0 0.0 0.0 0.3 10.4 0.0 17.7 15.4 0.3 9.6 0.7 0.0 0.1 0.0 0.2 0.2 0.4 0.7 0.4 0.1 0.4 0.2 0.4 6.3 6.1 5.0 6.0 3.9 5.4 4.4 4.4 8.7 3.9 4.0 5.0 0.0 7.5 4.8 3.7 5.7 4.3 0.2 0.2 0.2 0.6 0.2 0.3 0.4 0.2 0.3 0.2 0.4 0.2 9.4 0.0 6.0 15.0 17.2 6.4 9.3 9.1 7.4 7.8 6.9 8.6 10.1 8.6 4.4 16.5 2.1 22.3 15.7 6.4 15.6 7.9 27.7 3.1 12.5 8.2 11.4 5.9 25.3 7.1 18.3 10.0 10.2 4.5 28.5 10.0 8.9 14.8 14.6 13.5 36.6 11.7 18.3 7.9 8.2 71.6 13.1 11.4 12.4 28.1 9.8 9.3 17.5 45.8 27.1 5.6 2.7 8.6 17.1 9.4 8.6 25.7 2.7 8.2 26.3 9.0 9.1 27.9 16.9 10.8 9.9 29.7 13.7 11.9 10.6 6.0 EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.6;fallopian tube: 19.7" "Group enriched" "Detected in some" 4 "Early spermatids: 29.6;Endometrial ciliated cells: 31.9;Late spermatids: 20.1;Respiratory ciliated cells: 46.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;RPTEC TERT1: 1.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 8.9" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: AB_10672605, HPA057532: " "unprognostic (2.06e-3)" "unprognostic (1.87e-2)" "unprognostic (2.96e-2)" "unprognostic (4.34e-3)" "unprognostic (1.81e-1)" "unprognostic (7.59e-4)" "unprognostic (2.37e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-1)" "unprognostic (1.20e-1)" "unprognostic (5.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-2)" "unprognostic (4.59e-2)" 0.3 0.4 0.8 0.1 1.0 0.8 0.3 1.7 1.1 1.1 12.6 0.1 0.0 0.3 0.8 0.0 19.7 0.2 0.3 1.4 1.5 0.8 1.2 1.7 0.1 4.9 7.0 1.0 0.6 1.7 3.6 0.1 3.2 3.0 0.0 1.6 0.2 0.2 0.0 0.1 0.3 0.0 3.6 0.4 0.7 6.9 2.4 0.2 1.2 0.0 0.2 0.0 0.1 1.0 0.1 0.7 0.2 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 1.5 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.4 0.6 0.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.0 1.7 1.1 1.4 1.5 4.9 7.0 3.2 3.6 2.4 1.0 0.2 3.2 1.7 0.3 0.5 0.5 0.1 0.8 0.0 0.4 0.7 0.4 1.3 1.5 1.8 0.0 2.1 0.0 0.3 0.1 0.0 0.2 29.6 31.9 0.7 0.5 0.0 0.0 2.7 0.2 0.1 0.5 3.1 1.9 0.0 0.1 0.0 1.1 0.1 5.0 0.8 0.3 2.0 0.0 0.0 20.1 0.3 0.3 0.0 0.0 0.1 1.2 1.0 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.0 0.9 46.0 5.6 0.0 0.5 0.6 6.8 2.7 0.7 0.3 0.0 0.3 0.3 0.0 0.2 EFCAB13 "C17orf57, FLJ40342" ENSG00000178852 "EF-hand calcium binding domain 13" Q8IY85 17 47323290-47441312 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 20.5" "Group enriched" "Detected in many" 4 "Early spermatids: 169.8;Late spermatids: 185.7;Spermatocytes: 64.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002501, HPA021633, HPA023249, HPA026561" Uncertain Enhanced "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB002501: AB_564092, HPA021633: AB_1845594, HPA023249: AB_1845595, HPA026561: AB_1845596" "unprognostic (1.66e-1)" "unprognostic (3.48e-1)" "unprognostic (1.24e-2)" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.40e-1)" "unprognostic (7.43e-2)" "unprognostic (8.79e-3)" "unprognostic (8.75e-2)" "unprognostic (1.75e-2)" "unprognostic (1.46e-5)" "unprognostic (1.68e-1)" "unprognostic (1.61e-1)" "unprognostic (8.10e-2)" "unprognostic (1.90e-3)" 3.2 2.6 1.3 3.2 2.3 3.9 4.2 3.7 2.0 3.8 0.9 2.9 4.8 6.0 4.0 1.6 3.5 2.9 2.5 1.1 2.9 5.4 3.5 3.1 4.5 2.9 2.5 3.8 1.8 3.2 2.5 3.6 3.3 2.7 3.3 3.9 2.3 1.9 0.8 2.2 3.3 2.4 1.7 4.4 3.6 20.5 2.8 1.8 14.2 0.4 3.2 2.6 2.4 4.3 0.9 3.7 1.5 0.2 1.8 6.4 2.8 2.1 0.4 0.6 1.0 1.7 5.2 0.3 5.8 0.7 0.0 1.0 0.0 0.4 3.5 0.1 0.5 4.9 3.4 0.5 1.8 3.8 0.5 1.2 1.7 2.4 0.0 4.4 4.1 3.8 1.5 9.0 2.2 0.1 1.7 2.1 0.8 2.6 2.9 4.5 1.1 1.8 8.3 3.0 1.1 0.5 1.1 0.1 2.5 1.1 6.0 4.5 1.5 0.2 1.1 0.3 1.0 9.4 6.9 0.9 5.5 7.3 3.8 2.8 1.0 0.3 0.5 0.6 0.4 2.2 0.4 0.3 0.5 2.6 1.2 0.7 0.0 0.5 0.4 0.3 0.1 0.3 1.3 2.3 3.7 2.0 1.1 2.9 2.9 2.5 3.3 1.7 2.8 4.3 5.3 9.6 2.2 7.2 7.9 0.8 1.8 0.9 0.6 2.5 2.3 2.4 6.2 1.5 1.3 0.0 0.0 0.3 1.3 0.4 0.0 1.0 169.8 1.9 2.5 6.0 3.0 1.3 8.0 0.9 0.1 4.1 2.6 5.4 6.3 1.3 4.6 0.5 1.9 3.3 10.1 0.4 2.0 2.9 2.0 185.7 1.8 2.6 0.0 32.8 2.7 1.0 0.0 13.0 19.5 1.1 0.3 3.8 1.4 1.1 1.2 1.6 3.3 2.9 0.0 3.2 4.0 64.1 24.5 0.0 0.6 0.0 2.3 1.2 0.7 1.3 EFCAB14 KIAA0494 ENSG00000159658 "EF-hand calcium binding domain 14" O75071 1 46674659-46719146 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 159.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011224, HPA011938" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Nucleoli, Golgi apparatus" "HPA011224: AB_1852314, HPA011938: AB_1852317" "unprognostic (2.44e-1)" "unprognostic (5.90e-2)" "unprognostic (7.53e-2)" "unprognostic (2.36e-1)" "unprognostic (7.34e-2)" "unprognostic (4.55e-2)" "unprognostic (1.39e-2)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (3.00e-1)" "unprognostic (1.13e-3)" "unprognostic (1.00e-2)" "unprognostic (5.77e-2)" "unprognostic (1.94e-1)" "unprognostic (2.46e-1)" 49.8 23.8 26.0 25.4 35.5 8.5 30.5 31.9 21.3 42.4 15.5 37.4 30.2 31.7 24.7 39.6 38.4 33.3 36.1 21.3 28.1 44.2 30.6 43.0 26.2 37.5 33.7 35.8 23.1 159.5 18.0 43.6 33.4 30.7 39.3 12.3 30.5 40.1 34.6 28.7 31.5 38.9 29.9 31.7 65.9 27.3 29.9 34.1 43.9 45.9 35.2 40.1 27.1 38.2 34.9 20.3 13.4 23.8 75.2 48.6 37.3 35.4 56.7 40.3 40.6 22.4 23.1 26.5 38.5 51.6 53.7 41.0 28.1 41.3 51.7 62.4 16.9 33.8 15.1 8.7 26.9 44.3 67.1 43.9 61.5 31.4 28.2 37.4 52.6 26.3 23.5 37.9 37.7 12.4 30.6 10.6 22.2 39.8 21.1 22.1 45.9 25.2 37.6 68.4 7.4 9.9 47.7 64.2 29.9 43.3 29.0 38.6 46.0 33.1 16.8 38.1 37.0 38.0 65.2 22.7 43.6 34.5 25.9 23.4 22.6 36.8 25.3 28.0 34.0 18.0 23.0 22.9 19.5 17.0 21.0 21.7 15.4 21.8 26.3 14.1 21.1 24.3 26.0 35.5 31.9 21.3 21.3 28.1 37.5 33.7 33.4 29.9 29.9 38.2 152.3 73.7 84.6 31.3 45.9 31.7 52.3 32.0 44.9 31.6 56.3 34.0 44.9 47.1 46.1 114.0 31.3 40.6 64.4 80.8 31.3 36.2 70.6 36.1 37.4 74.8 37.8 31.1 20.3 38.4 32.0 48.8 79.0 52.2 101.8 27.4 50.7 57.9 42.2 47.1 27.8 64.6 54.9 75.5 44.0 18.9 47.2 52.0 26.6 29.0 65.0 50.6 84.5 29.7 46.2 48.5 61.3 49.7 34.8 73.8 50.5 34.4 49.9 18.6 26.3 50.2 49.9 51.3 27.7 46.5 43.5 59.0 52.0 30.4 46.2 128.4 EFCAB7 "KIAA1799, RP4-534K7.1" ENSG00000203965 "EF-hand calcium binding domain 7" A8K855 1 63523372-63572693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 55.3;Excitatory neurons: 58.9;Inhibitory neurons: 47.7;Oligodendrocyte precursor cells: 41.7;Spermatocytes: 73.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029611, HPA029612, HPA029613" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli, Nucleoli rim" "Plasma membrane, Cytosol" "HPA029611: AB_10599972, HPA029612: AB_10600533, HPA029613: AB_10601004" "unprognostic (8.81e-2)" "unprognostic (5.24e-2)" "unprognostic (5.13e-2)" "unprognostic (1.64e-1)" "prognostic favorable (3.65e-4)" "unprognostic (1.70e-2)" "unprognostic (6.53e-4)" "unprognostic (2.99e-1)" "unprognostic (5.81e-3)" "unprognostic (1.69e-1)" "unprognostic (6.28e-2)" "unprognostic (1.66e-1)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (6.97e-2)" "unprognostic (9.90e-2)" "unprognostic (2.73e-1)" 2.7 5.3 7.3 2.2 7.6 2.0 6.0 8.9 10.3 5.8 10.1 3.4 2.0 6.1 6.2 2.9 8.1 4.6 6.5 7.4 9.3 5.6 1.7 4.0 3.6 6.8 7.2 8.0 2.9 10.4 5.9 3.2 7.0 5.4 3.0 8.9 3.1 5.0 6.7 3.1 2.1 4.7 6.5 2.7 3.2 14.6 8.2 7.3 5.9 3.9 3.3 3.7 2.8 8.3 6.5 5.7 7.1 4.5 7.5 11.0 3.6 4.1 4.6 7.2 8.8 1.7 5.0 4.4 9.6 2.5 14.5 6.0 6.1 4.1 8.5 8.6 4.3 3.6 10.4 3.9 4.6 5.1 3.2 6.1 9.9 8.6 5.6 11.4 6.1 8.2 4.8 7.3 4.7 1.5 9.9 3.5 3.1 4.6 5.6 6.2 10.7 4.6 11.1 3.6 15.2 5.8 8.1 4.5 10.5 9.6 4.5 3.8 1.7 4.1 3.5 12.1 4.0 4.7 8.7 5.0 7.4 3.5 6.0 10.1 0.4 0.1 1.2 0.3 1.6 1.8 1.4 1.4 0.8 1.9 1.4 1.3 0.0 1.3 2.6 1.0 1.6 0.6 7.3 7.6 8.9 10.3 7.4 9.3 6.8 7.2 7.0 6.5 8.2 8.3 3.1 12.8 4.1 23.2 6.0 3.1 5.6 7.0 5.7 7.7 2.6 3.9 7.8 2.8 5.6 5.5 4.2 3.7 2.1 0.6 7.9 3.8 55.3 19.9 8.0 3.2 1.8 1.3 58.9 0.7 2.0 5.6 3.6 3.4 2.5 7.9 2.2 1.2 2.6 0.0 47.7 1.3 8.2 2.5 1.6 8.8 10.8 1.8 1.8 14.0 1.9 5.2 2.1 41.7 21.9 1.4 0.3 13.5 6.0 1.4 0.5 5.5 27.5 11.3 26.3 11.8 5.3 73.4 22.7 3.8 2.3 1.2 3.4 5.8 2.1 1.6 EFHC2 "FLJ22843, MRX74" ENSG00000183690 "EF-hand domain containing 2" Q5JST6 X 44147872-44343672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 17.1;fallopian tube: 14.7" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Early spermatids: 78.6;Endometrial ciliated cells: 55.3;Respiratory ciliated cells: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 16.4;NK-cell: 5.8" "Group enriched" "Detected in many" 7 "granulocytes: 16.4;NK-cells: 5.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.7;HEL: 3.7;HMC-1: 12.0;NB-4: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034492 Approved Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "HPA034492: AB_10671227" "unprognostic (1.93e-1)" "unprognostic (7.80e-3)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (6.83e-3)" "unprognostic (5.07e-2)" "unprognostic (4.29e-2)" "unprognostic (1.75e-2)" "unprognostic (3.50e-2)" "unprognostic (2.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (7.89e-2)" "unprognostic (1.06e-1)" "unprognostic (6.13e-4)" "unprognostic (1.64e-3)" "unprognostic (4.97e-2)" 0.4 0.3 1.5 0.3 1.9 1.4 0.7 1.0 1.4 2.7 17.1 1.1 0.3 3.7 3.4 1.8 14.7 1.4 3.7 1.5 2.1 1.8 0.0 2.0 0.2 5.2 3.9 1.7 0.1 0.2 3.1 0.8 2.8 1.9 0.3 2.0 8.2 3.6 0.0 3.5 0.5 1.6 2.7 0.3 0.9 6.7 2.5 0.5 2.3 0.1 0.4 0.5 0.9 2.6 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 3.7 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 12.0 0.2 0.2 0.1 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 16.4 0.0 0.0 1.5 0.0 0.6 0.1 0.6 0.1 0.3 0.1 0.5 0.7 1.5 5.8 0.0 0.0 0.0 0.9 1.5 1.9 1.0 1.4 1.5 2.1 5.2 3.9 2.8 2.7 2.5 2.6 0.1 0.0 3.9 32.0 0.0 3.1 6.0 9.6 1.2 0.2 0.4 0.5 10.8 4.3 5.1 0.0 2.1 0.0 1.6 1.2 1.9 0.9 78.6 55.3 6.0 0.3 0.0 1.7 7.2 5.9 0.1 0.8 0.0 17.1 16.4 3.8 0.4 0.0 0.3 0.0 1.7 1.5 4.1 0.0 0.4 19.0 6.8 4.9 0.0 0.0 0.4 5.3 3.1 1.5 0.2 1.0 0.0 7.2 0.2 1.0 3.8 0.7 79.6 0.1 6.6 0.1 3.7 11.3 10.5 7.3 2.8 0.3 1.6 0.4 5.2 6.0 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 EFTUD2 "SNRNP116, Snrp116, Snu114, U5-116KD" ENSG00000108883 "Elongation factor Tu GTP binding domain containing 2" Q15029 17 44849948-44899445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022021 Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 94000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Cytosol" "HPA022021: AB_1848032" "unprognostic (4.28e-2)" "unprognostic (4.12e-2)" "unprognostic (1.98e-3)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (4.98e-2)" "prognostic unfavorable (2.71e-6)" "unprognostic (6.94e-2)" "unprognostic (4.52e-1)" "unprognostic (2.37e-1)" "unprognostic (4.11e-3)" "unprognostic (5.19e-2)" "unprognostic (5.48e-3)" "unprognostic (1.62e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" 23.6 30.7 26.7 31.3 27.2 37.4 22.4 24.6 28.0 17.6 27.9 26.5 21.6 19.4 18.8 33.1 25.0 16.3 35.3 28.0 26.3 26.1 26.2 22.6 35.5 25.6 26.1 17.6 24.0 27.9 13.2 28.6 26.4 17.8 28.8 15.5 22.5 18.6 65.8 28.5 22.8 23.5 25.1 29.8 22.5 27.5 27.3 41.0 21.2 38.3 46.5 28.8 20.3 26.6 88.7 173.6 82.8 134.9 61.9 60.9 97.1 68.7 91.4 169.6 146.0 134.6 73.9 152.1 79.0 87.1 130.3 98.6 181.5 120.2 196.2 153.9 150.8 150.9 100.9 144.5 68.2 179.9 107.5 66.5 67.4 157.2 85.0 65.2 149.1 134.8 189.6 57.8 98.0 88.2 182.3 118.6 85.7 206.8 143.1 126.1 168.1 132.0 97.0 97.8 135.7 81.1 67.7 49.5 73.9 120.6 131.6 112.2 91.4 126.5 97.4 77.7 176.3 60.2 81.4 150.0 101.6 98.4 132.0 42.7 84.3 85.9 37.2 81.6 41.7 32.3 32.9 36.1 82.8 31.3 28.8 32.2 13.0 44.2 85.0 35.5 35.2 70.7 26.7 27.2 24.6 28.0 28.0 26.3 25.6 26.1 26.4 25.1 27.3 26.6 11.3 0.0 14.0 11.1 18.1 11.7 12.2 15.1 13.6 14.7 14.1 11.8 21.1 22.8 15.3 18.4 33.3 34.5 14.0 15.6 3.9 29.4 12.5 17.8 17.9 21.4 10.8 24.8 17.5 26.7 30.9 14.0 18.3 18.8 19.7 22.6 21.8 22.4 38.5 26.9 17.2 13.4 16.2 30.1 17.5 6.5 12.8 26.2 5.4 12.2 46.7 12.0 21.6 6.0 15.5 27.7 12.0 9.1 20.3 14.5 15.9 13.2 17.4 18.0 19.7 14.8 14.8 28.2 43.3 16.0 14.6 27.2 16.3 21.4 22.2 12.5 EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 461.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 760.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA047165: AB_2679965, HPA051029: AB_2681317" "unprognostic (2.04e-3)" "unprognostic (2.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-2)" "unprognostic (6.38e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.01e-1)" 53.4 32.6 61.1 36.2 62.5 23.2 72.6 59.7 72.4 51.3 59.8 77.8 49.6 46.2 57.4 80.8 50.8 46.3 55.7 60.2 61.5 61.0 248.4 45.0 28.4 60.2 62.5 42.4 101.8 461.9 30.6 48.5 60.2 49.6 80.4 39.4 75.3 58.0 119.5 70.2 49.3 62.5 62.4 30.5 59.7 33.1 64.4 35.3 40.5 104.6 42.3 78.9 48.4 61.0 156.6 115.6 129.5 160.5 207.7 155.9 162.4 159.6 116.8 104.3 93.4 178.9 303.4 158.0 264.0 146.5 110.8 176.1 199.0 326.8 135.2 42.0 142.6 760.9 77.2 179.9 154.1 170.9 78.4 147.5 292.7 157.4 230.2 102.8 223.9 85.1 351.1 61.1 149.4 113.8 79.0 96.4 173.6 398.3 139.5 113.9 155.4 132.8 177.0 272.4 120.1 116.9 187.1 215.5 63.4 212.3 436.4 165.7 195.2 133.8 93.3 94.7 128.7 39.7 84.8 200.5 58.5 256.1 182.2 4.3 7.0 5.9 7.2 6.7 7.2 8.4 5.7 9.0 10.9 6.3 8.1 6.7 0.8 6.5 4.9 14.5 9.1 5.3 61.1 62.5 59.7 72.4 60.2 61.5 60.2 62.5 60.2 62.4 64.4 61.0 73.5 32.1 38.3 13.4 34.8 120.6 130.3 132.6 120.1 58.9 148.8 100.6 61.9 124.4 69.5 110.3 37.5 166.9 32.4 66.4 144.8 178.6 31.1 34.4 59.3 87.1 98.4 102.7 25.1 181.8 201.2 80.1 87.7 46.5 27.3 76.2 74.6 575.0 110.5 82.4 24.0 115.3 105.8 49.8 96.1 49.7 71.4 40.9 90.7 11.2 40.9 107.1 50.4 13.0 23.0 182.1 67.6 72.2 79.1 270.0 68.5 122.7 43.9 36.9 46.0 60.8 80.1 95.9 112.3 176.3 181.4 140.1 31.0 71.3 135.7 189.4 EIF1AD "haponin, MGC11102" ENSG00000175376 "Eukaryotic translation initiation factor 1A domain containing" Q8N9N8 11 65996545-66002176 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054991, HPA058735" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" Cytosol "HPA054991: AB_2682664, HPA058735: AB_2683802" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.86e-2)" "unprognostic (1.17e-1)" "unprognostic (8.76e-2)" "unprognostic (1.36e-3)" "unprognostic (2.31e-1)" "unprognostic (1.59e-3)" "unprognostic (7.63e-3)" "unprognostic (1.40e-1)" "unprognostic (1.28e-3)" "unprognostic (3.96e-1)" 15.7 17.7 15.3 19.9 15.8 44.6 16.0 18.7 19.8 13.1 14.4 15.8 15.1 15.9 16.2 21.0 15.3 13.0 17.1 16.4 17.7 15.2 17.3 15.0 23.4 16.1 15.7 20.4 19.2 17.1 16.6 21.1 16.3 13.4 14.7 16.6 16.8 14.9 27.2 23.1 16.9 14.8 14.8 20.0 16.1 19.4 17.3 19.9 13.8 23.3 27.6 17.1 14.5 18.4 51.0 43.9 35.0 35.9 27.6 28.8 32.8 36.4 34.6 44.2 37.7 44.8 47.5 38.2 62.6 41.2 38.0 34.9 42.2 48.8 41.5 35.1 21.7 54.4 52.0 46.4 33.7 50.3 41.8 24.1 41.9 65.3 44.1 31.2 31.0 40.9 81.1 54.4 64.7 68.7 46.6 55.1 25.9 23.3 47.5 50.3 35.9 75.0 25.6 31.8 26.5 31.2 39.3 54.7 41.5 28.1 53.1 31.0 36.5 59.7 39.9 47.8 36.1 66.7 85.5 79.8 42.9 33.8 39.5 52.6 20.5 13.5 17.7 16.6 13.6 19.4 15.0 13.0 21.3 19.0 14.1 13.5 13.1 16.4 21.3 12.7 15.3 13.3 15.3 15.8 18.7 19.8 16.4 17.7 16.1 15.7 16.3 14.8 17.3 18.4 8.2 3.2 5.4 3.3 16.2 37.7 12.2 13.4 12.5 7.2 14.2 9.1 16.2 14.3 7.3 5.5 14.6 16.3 17.7 11.6 15.6 12.7 18.3 9.0 8.3 11.6 2.4 21.0 3.0 13.1 23.0 11.4 7.1 10.5 12.7 31.7 16.4 16.5 24.5 11.8 2.8 11.2 6.1 10.4 29.5 14.3 12.2 14.4 12.4 1.0 17.6 10.5 17.5 5.5 4.5 29.0 15.2 5.7 22.6 13.2 13.8 15.7 10.6 18.5 6.6 9.8 27.0 31.3 23.2 15.7 48.9 25.3 16.2 7.4 10.9 13.2 EIF2B2 "EIF-2Bbeta, EIF2B" ENSG00000119718 "Eukaryotic translation initiation factor 2B subunit beta" P49770 14 75002921-75012366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005841, CAB037105, HPA048028" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 12000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB037105: AB_1840834, HPA005841: AB_1078725, HPA048028: AB_2680235" "unprognostic (1.10e-1)" "unprognostic (4.41e-2)" "unprognostic (5.70e-2)" "unprognostic (6.71e-2)" "unprognostic (7.64e-2)" "unprognostic (3.45e-3)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "prognostic favorable (2.95e-4)" "unprognostic (4.15e-2)" "unprognostic (2.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" 2.7 5.3 4.0 2.9 4.5 3.2 3.6 8.7 4.8 3.9 2.2 3.0 3.0 3.6 4.9 3.8 3.1 4.0 3.9 3.6 6.1 4.9 3.3 2.7 4.0 4.5 4.2 2.9 4.0 8.5 3.5 4.8 4.5 4.1 3.8 6.8 2.8 4.5 5.5 4.0 2.8 3.4 2.9 2.7 2.6 3.9 4.8 3.9 11.5 7.1 4.2 4.0 2.6 6.9 5.9 7.0 5.6 6.4 6.3 5.2 7.4 3.7 6.1 7.1 8.2 9.0 5.9 5.2 2.3 5.8 4.5 4.4 8.8 8.7 10.6 3.2 6.5 4.6 6.3 6.2 8.2 3.4 5.3 4.8 8.2 9.1 9.3 6.1 24.8 4.5 4.2 4.9 15.5 17.4 5.5 4.3 4.0 7.3 10.3 3.4 6.6 4.3 10.1 7.0 6.0 4.8 3.9 5.5 8.4 6.9 9.0 3.2 6.4 5.4 5.2 2.4 4.8 8.4 7.5 6.2 5.9 4.3 4.2 4.2 1.8 1.4 3.0 1.9 2.5 2.1 2.6 2.5 2.4 2.0 1.9 2.0 1.0 3.3 1.8 2.0 4.0 2.5 4.0 4.5 8.7 4.8 3.6 6.1 4.5 4.2 4.5 2.9 4.8 6.9 18.9 19.2 11.5 6.2 14.1 17.7 19.5 28.9 18.2 28.2 15.4 17.0 18.2 22.8 21.5 25.8 45.9 51.5 16.1 15.3 41.1 36.2 12.1 17.0 14.5 32.1 15.6 20.8 5.3 33.1 56.5 18.3 12.8 12.8 21.5 17.5 13.2 11.9 33.7 28.6 5.4 9.0 20.3 19.1 11.9 12.7 15.8 18.8 14.2 1.9 28.0 27.3 28.8 2.5 8.5 28.1 11.7 16.1 11.3 17.5 19.0 50.8 17.2 29.4 26.3 16.9 27.9 84.2 27.4 27.3 21.9 165.5 14.9 30.5 19.7 19.2 EIF4E "EIF4E1, EIF4EL1, EIF4F" ENSG00000151247 "Eukaryotic translation initiation factor 4E" P06730 4 98879276-98929133 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Autism, Autism spectrum disorder, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 927.0;Late spermatids: 2284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004077, CAB016316, HPA068358" Supported Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA 450000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Cytosol, Cytoplasmic bodies" Nucleoplasm "CAB004077: AB_823488, CAB016316: AB_627502, HPA068358: " "unprognostic (3.07e-3)" "unprognostic (1.43e-1)" "unprognostic (6.53e-3)" "unprognostic (7.52e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-3)" "unprognostic (2.03e-5)" "unprognostic (6.55e-3)" "unprognostic (1.09e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (1.10e-3)" "unprognostic (5.40e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" 38.0 37.4 27.4 37.7 28.5 57.4 35.6 32.5 34.6 28.5 20.9 45.1 35.9 30.5 38.0 51.7 31.7 31.3 37.5 27.8 34.3 47.4 43.3 27.0 44.6 29.2 31.1 29.1 27.0 45.1 17.0 35.9 29.2 31.4 52.2 54.0 31.2 30.7 39.2 24.2 34.4 39.4 36.2 31.5 35.8 62.6 31.4 53.2 52.6 48.1 58.0 54.4 29.8 34.3 101.1 85.2 139.8 96.5 73.4 74.2 87.3 184.6 105.3 137.0 100.5 111.0 122.7 194.7 59.4 104.4 94.3 49.0 181.9 124.9 158.9 133.5 56.2 135.6 52.7 105.8 62.6 199.3 104.8 54.5 78.3 104.8 82.9 81.5 108.3 97.6 226.6 95.2 120.0 82.9 189.2 110.6 115.0 189.2 72.2 119.7 94.4 90.0 122.0 85.3 123.3 80.3 85.5 188.4 65.4 93.3 89.9 85.9 86.5 110.0 121.6 96.9 153.7 71.4 185.4 179.4 99.7 102.7 127.1 39.5 34.7 59.3 38.2 42.1 44.4 50.0 43.2 40.2 39.6 43.6 47.3 47.3 26.3 54.3 54.8 33.5 46.5 50.3 27.4 28.5 32.5 34.6 27.8 34.3 29.2 31.1 29.2 36.2 31.4 34.3 45.2 32.1 42.2 29.7 93.1 362.1 227.5 202.2 149.7 87.9 81.6 41.1 27.5 55.8 106.0 60.7 35.5 105.3 56.2 140.5 256.3 88.9 927.0 76.1 84.0 77.8 64.6 192.8 45.2 67.4 150.0 87.1 80.0 119.0 51.4 28.0 40.0 77.1 121.1 85.8 45.0 77.4 227.9 61.9 327.6 2284.9 50.7 122.1 193.9 25.3 69.8 82.0 57.7 35.2 50.9 83.8 107.1 49.2 113.0 191.1 83.2 189.2 76.8 64.7 52.6 78.7 151.7 98.7 87.1 171.2 370.9 119.0 82.2 39.8 97.3 224.3 EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 990.0;Late spermatids: 2765.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 750000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: AB_10601368" "unprognostic (2.83e-1)" "unprognostic (9.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.61e-2)" "unprognostic (2.72e-3)" "unprognostic (1.79e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-2)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.68e-2)" "unprognostic (1.27e-2)" 186.9 174.9 151.0 117.8 159.3 283.3 168.3 163.8 157.3 179.8 129.6 208.4 130.2 186.4 76.6 249.3 163.6 100.0 171.0 149.9 151.9 156.6 197.0 158.4 130.3 161.9 156.9 181.2 226.4 160.7 119.9 162.8 162.2 150.3 100.2 149.8 170.1 125.1 399.8 230.9 148.9 119.2 165.2 137.4 192.9 79.9 164.6 150.2 141.2 173.4 137.2 175.3 179.7 187.1 526.3 341.4 251.3 303.1 220.8 231.8 283.4 359.8 276.3 300.3 289.5 423.3 388.6 444.3 96.6 338.8 424.2 266.6 280.5 481.5 286.3 298.0 329.2 247.5 305.2 345.9 253.1 429.0 236.9 273.2 300.8 326.2 460.7 341.5 326.8 260.1 445.8 186.4 305.2 448.2 342.0 516.8 337.6 430.3 328.9 386.9 342.7 401.5 250.9 324.7 252.7 325.4 340.9 420.3 296.0 331.3 476.8 272.4 340.2 411.6 284.6 345.1 474.4 218.8 299.8 771.4 326.3 435.1 441.4 213.7 229.7 245.6 156.9 255.6 164.5 146.4 161.4 158.3 224.2 132.9 183.9 151.7 150.1 193.5 270.2 95.1 194.7 388.0 151.0 159.3 163.8 157.3 149.9 151.9 161.9 156.9 162.2 165.2 164.6 187.1 105.8 83.3 81.2 15.7 97.1 119.2 153.8 101.5 78.0 93.1 103.0 95.5 43.3 68.6 68.7 44.1 25.0 198.8 91.9 98.7 107.6 148.1 990.0 104.8 98.3 103.0 90.4 79.5 25.3 157.7 381.4 101.6 61.2 112.5 122.4 112.1 79.6 95.7 124.2 97.6 24.6 87.2 91.6 101.2 102.7 2765.8 103.8 86.8 72.9 15.9 157.4 134.7 119.4 16.6 44.2 147.0 82.8 110.6 82.7 140.7 84.6 69.0 57.8 72.3 85.5 107.3 117.7 61.2 64.6 90.1 116.1 395.3 92.4 116.9 109.5 140.4 EIF5A "EIF-5A, EIF5A1, MGC104255, MGC99547" ENSG00000132507 "Eukaryotic translation initiation factor 5A" P63241 17 7306999-7312463 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005042, HPA061298, HPA074052" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Plasma membrane" "CAB005042: AB_562281, HPA061298: AB_2684472, HPA074052: " "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (8.10e-2)" "unprognostic (2.80e-1)" "unprognostic (6.95e-2)" "unprognostic (1.39e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (4.10e-1)" "unprognostic (4.11e-2)" "unprognostic (1.64e-2)" "unprognostic (8.25e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (3.53e-1)" "unprognostic (2.79e-1)" "unprognostic (6.01e-2)" "unprognostic (7.65e-2)" 317.2 309.3 82.3 138.3 83.8 221.5 240.7 85.5 99.0 222.7 77.8 247.5 113.0 206.2 85.8 575.9 188.1 73.7 316.1 87.8 89.8 241.7 495.6 244.5 135.0 87.7 86.4 161.2 295.0 79.7 166.7 96.4 93.0 189.1 125.7 47.6 230.9 65.6 572.1 407.8 207.5 106.1 86.5 227.4 226.7 201.7 92.3 122.5 181.6 160.3 154.4 221.3 281.8 88.6 838.2 958.6 275.8 570.6 220.8 270.2 427.1 546.2 360.7 730.1 501.6 583.6 343.3 749.7 350.9 451.4 300.3 572.3 610.0 777.8 665.9 466.2 987.2 477.9 710.1 750.6 388.6 324.0 431.7 302.5 374.9 587.8 736.0 259.1 501.4 232.0 673.8 192.2 527.3 496.2 388.6 523.3 525.8 477.2 498.0 412.0 320.5 732.4 464.6 393.8 340.5 431.8 330.0 469.4 360.8 212.3 327.2 258.4 427.7 567.6 379.5 326.2 896.4 168.8 229.9 443.6 515.1 527.2 642.2 146.8 137.6 102.0 157.4 193.1 187.5 154.5 153.1 137.2 215.9 149.1 139.6 144.6 62.0 195.1 186.5 225.0 156.7 200.3 82.3 83.8 85.5 99.0 87.8 89.8 87.7 86.4 93.0 86.5 92.3 88.6 180.1 54.5 37.9 6.2 241.9 349.0 67.9 226.5 378.5 88.3 258.8 138.7 77.8 125.8 72.7 62.5 14.6 324.3 200.3 316.0 74.3 317.3 153.8 136.4 255.2 176.6 150.6 456.1 6.8 239.8 633.8 199.6 172.8 187.8 138.4 87.3 105.7 236.4 296.8 50.5 7.0 317.4 83.4 133.6 283.1 112.9 100.6 151.9 263.3 4.7 245.0 122.2 216.3 2.0 11.5 322.0 223.7 81.3 386.7 507.1 229.3 127.1 41.3 65.0 92.1 160.7 262.1 200.4 82.6 572.0 313.7 428.4 179.3 290.7 384.7 207.0 EIPR1 "EIPR-1, TSSC1" ENSG00000032389 "EARP complex and GARP complex interacting protein 1" Q53HC9 2 3188925-3377830 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 48.6;Distal tubular cells: 50.9;Ductal cells: 28.7;Extravillous trophoblasts: 36.9;Hofbauer cells: 34.0;Proximal tubular cells: 41.6;Syncytiotrophoblasts: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031231, HPA031232, HPA031233, HPA031234" Approved Supported "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "Intermediate filaments" "HPA031231: AB_10669881, HPA031232: AB_10603222, HPA031233: AB_10670026, HPA031234: AB_2673803" "unprognostic (2.16e-1)" "unprognostic (2.22e-1)" "unprognostic (2.71e-1)" "unprognostic (1.66e-1)" "unprognostic (4.27e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (3.67e-7)" "unprognostic (1.94e-1)" "unprognostic (1.57e-1)" "unprognostic (7.83e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (1.78e-1)" "unprognostic (1.02e-2)" "unprognostic (3.43e-1)" "unprognostic (2.24e-2)" "unprognostic (3.83e-2)" 8.5 15.2 24.8 13.8 25.6 18.2 9.8 24.3 27.3 9.3 20.5 13.6 12.2 9.9 19.4 19.7 13.2 7.7 11.9 26.0 26.2 17.9 16.5 9.3 19.2 22.2 23.2 6.9 10.5 15.8 27.8 9.1 23.9 9.5 11.8 15.9 11.2 7.8 14.0 13.9 10.6 10.6 22.9 14.6 10.8 11.6 25.1 22.2 22.4 15.2 18.0 10.8 11.1 23.6 25.4 48.2 25.9 28.2 15.7 21.1 56.2 26.8 27.8 32.0 24.2 32.5 32.6 45.3 46.8 28.3 30.1 25.9 20.9 39.3 17.3 35.5 37.5 40.7 28.4 76.2 29.9 40.2 49.9 19.5 35.1 32.2 43.6 17.6 41.9 79.0 45.2 30.9 29.7 48.5 37.6 57.9 29.4 61.5 38.1 43.6 26.6 61.6 39.6 35.7 54.5 62.6 18.5 31.7 30.1 13.8 29.0 36.9 29.9 25.3 13.1 21.2 36.9 34.9 88.0 37.8 30.0 40.8 24.1 22.2 15.2 12.8 19.7 17.9 19.6 16.8 16.1 20.6 27.4 20.6 17.6 18.8 6.5 22.2 16.7 30.3 22.2 18.6 24.8 25.6 24.3 27.3 26.0 26.2 22.2 23.2 23.9 22.9 25.1 23.6 5.6 3.2 9.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 8.5 7.0 0.0 0.0 6.2 20.2 0.0 48.6 7.0 0.0 50.9 28.7 0.0 14.9 7.5 7.0 0.0 0.0 0.0 16.0 36.9 5.0 0.0 11.5 3.8 13.7 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.3 0.0 0.0 41.6 4.4 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 26.7 5.7 24.5 0.0 0.0 ELAVL1 "Hua, HUR, MelG" ENSG00000066044 "ELAV like RNA binding protein 1" Q15717 19 7958573-8005659 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 227.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005256, HPA046298" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 230000 "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "CAB005256: AB_2096342, HPA046298: AB_2679618" "unprognostic (1.19e-1)" "unprognostic (9.66e-3)" "unprognostic (2.46e-2)" "unprognostic (3.98e-1)" "unprognostic (1.04e-1)" "unprognostic (6.37e-3)" "unprognostic (1.81e-2)" "unprognostic (8.44e-2)" "unprognostic (3.75e-2)" "prognostic favorable (4.93e-4)" "unprognostic (2.09e-1)" "unprognostic (1.59e-2)" "unprognostic (7.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 27.5 27.7 14.5 33.1 15.6 27.8 25.0 16.0 15.7 29.4 19.5 27.9 25.2 31.6 25.9 30.0 34.3 22.4 34.0 15.3 15.9 24.8 29.0 24.2 40.2 13.7 15.6 31.8 28.4 37.5 21.4 32.7 13.8 26.9 27.2 19.0 29.6 29.4 37.7 24.9 25.1 35.9 16.2 30.1 24.6 46.1 15.1 52.7 27.9 32.2 44.1 37.4 25.2 16.6 127.5 84.1 137.9 104.5 52.9 52.7 76.5 89.5 78.4 136.9 106.3 122.4 73.2 153.2 125.5 104.0 76.9 86.0 155.2 107.9 114.8 134.9 131.8 135.5 58.9 115.7 77.4 129.9 103.1 65.8 63.6 95.7 57.7 64.8 106.2 115.6 140.7 112.6 95.7 95.8 215.3 103.7 122.1 96.4 101.6 239.0 89.6 100.9 87.5 93.9 98.0 70.8 88.9 89.1 71.7 82.6 101.8 101.4 79.7 127.3 87.3 119.2 161.8 109.8 114.7 161.9 71.3 154.2 112.2 29.9 19.7 37.2 16.4 17.2 17.0 20.8 24.0 26.3 25.0 27.7 21.8 16.6 5.3 33.1 22.1 12.5 20.9 16.3 14.5 15.6 16.0 15.7 15.3 15.9 13.7 15.6 13.8 16.2 15.1 16.6 45.7 25.6 23.1 18.6 56.0 72.4 79.5 29.0 51.2 47.2 54.9 37.2 31.3 30.0 20.7 47.8 56.3 86.8 48.1 32.9 66.5 37.1 227.7 41.6 46.5 52.2 42.0 95.7 20.3 33.8 102.3 53.1 40.2 47.2 21.0 59.5 47.2 89.2 64.2 60.6 21.5 52.9 18.3 57.5 79.2 164.1 50.4 47.3 51.6 23.4 43.9 43.4 57.7 33.7 26.9 35.3 45.7 56.8 88.7 98.2 38.3 65.8 27.3 55.7 52.6 45.5 71.0 164.7 61.2 72.0 71.0 74.8 50.9 44.7 60.2 84.6 ELL "C19orf17, ELL1, Men, PPP1R68" ENSG00000105656 "Elongation factor for RNA polymerase II" P55199 19 18442663-18522116 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 297.2;Late spermatids: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004202, HPA046076" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA004202: , HPA046076: AB_2679526" "unprognostic (9.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (8.26e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (3.00e-2)" "unprognostic (6.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.57e-1)" "unprognostic (2.07e-1)" "unprognostic (5.12e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 15.1 7.7 4.0 9.0 6.2 29.8 11.8 8.4 7.0 11.2 5.0 10.6 6.5 11.0 2.0 10.3 10.6 5.7 10.5 3.6 4.2 12.6 14.1 16.6 7.6 4.7 4.2 13.0 10.0 4.1 11.3 10.0 3.8 9.9 2.3 1.2 8.3 3.6 20.1 15.3 12.8 3.6 4.0 17.3 10.1 38.5 6.1 6.8 8.2 9.9 4.3 10.5 11.0 3.9 12.7 5.7 3.2 6.8 3.4 4.2 22.7 10.0 8.8 7.5 7.1 7.1 9.8 15.6 11.8 6.7 5.2 8.6 4.7 11.1 3.8 13.3 10.9 9.4 5.9 6.3 5.2 10.3 11.8 8.6 9.3 9.8 7.7 5.6 5.4 8.5 13.5 21.8 4.0 10.3 12.5 11.9 10.6 7.8 16.8 10.9 4.8 17.4 5.3 8.8 5.7 6.4 7.4 12.3 11.0 4.1 6.4 12.4 9.0 8.6 6.6 11.6 9.3 34.8 23.4 11.7 11.4 17.6 12.5 0.3 5.9 4.5 4.5 4.1 7.3 2.9 2.6 3.9 5.0 2.1 1.7 2.7 18.1 2.3 2.1 8.6 3.1 4.1 4.0 6.2 8.4 7.0 3.6 4.2 4.7 4.2 3.8 4.0 6.1 3.9 12.3 6.4 6.1 9.1 16.3 28.0 26.4 11.9 23.3 4.5 19.7 10.7 5.1 11.5 7.2 3.7 4.2 47.5 29.5 15.2 11.7 8.7 297.2 22.9 16.0 11.4 19.7 10.3 9.1 8.0 17.6 17.2 12.8 37.7 11.4 5.1 7.5 15.5 19.3 1.7 11.2 10.1 6.1 12.8 21.7 235.9 6.5 20.4 7.2 9.4 13.8 5.3 4.1 7.1 8.0 10.8 3.7 3.0 53.6 14.2 11.8 7.0 8.4 3.4 19.7 13.0 16.7 18.2 24.7 19.4 30.4 68.7 19.2 5.9 7.1 19.9 ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Gastric mucus-secreting cells: 4.6;Proximal enterocytes: 6.5;Squamous epithelial cells: 21.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cell line enhanced" "Detected in many" "Daudi: 73.8;OE19: 28.5;T-47d: 39.0;U-698: 149.9" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" 0.5 0.9 1.0 9.7 1.0 0.2 5.2 1.0 1.1 1.6 4.7 8.0 14.1 0.6 1.1 4.5 3.9 0.7 0.5 1.0 1.1 1.4 0.7 1.5 49.7 1.0 1.1 1.7 0.4 1.6 0.5 3.7 1.1 2.0 12.3 0.1 2.2 1.0 0.4 25.0 12.9 1.0 1.0 1.0 1.8 16.2 1.4 1.5 0.7 1.9 57.7 0.7 0.8 1.1 2.1 0.2 0.6 1.1 4.9 1.2 0.4 0.2 1.3 2.8 3.1 0.0 1.3 73.8 0.1 1.2 0.1 13.7 1.3 0.7 1.4 1.6 7.3 0.4 2.6 4.6 1.0 0.1 0.0 1.4 12.3 0.7 0.2 0.2 1.1 0.4 0.2 0.0 0.7 4.0 1.5 1.4 0.1 28.5 2.4 0.8 0.0 0.0 1.8 0.0 9.5 0.0 1.7 21.5 0.0 0.3 39.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 149.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 10.5 0.6 0.1 0.0 15.9 1.1 0.2 0.0 0.1 0.0 2.2 0.6 0.6 1.0 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.1 1.0 1.4 1.1 0.1 0.0 0.0 0.0 2.2 0.4 0.1 0.2 5.2 0.0 0.7 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.2 0.0 0.1 1.8 0.4 0.1 0.2 0.0 0.4 0.1 0.7 0.0 0.5 4.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.5 0.0 0.0 0.5 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 6.5 0.1 3.1 0.0 0.0 0.2 0.4 0.2 0.2 21.0 1.0 0.3 0.1 0.1 2.3 0.2 ELMOD2 MGC10084 ENSG00000179387 "ELMO domain containing 2" Q8IZ81 4 140524168-140553770 "Predicted intracellular proteins" "Antiviral defense" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047600 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoli, Cytosol" Nucleoplasm "HPA047600: AB_2680098" "unprognostic (1.39e-1)" "unprognostic (1.91e-1)" "unprognostic (6.70e-3)" "unprognostic (2.10e-3)" "unprognostic (4.91e-2)" "unprognostic (3.93e-1)" "unprognostic (1.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" "unprognostic (7.93e-2)" "unprognostic (1.05e-2)" "unprognostic (3.65e-1)" "prognostic favorable (1.17e-8)" "unprognostic (3.17e-1)" "unprognostic (4.03e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (1.82e-2)" 10.7 13.8 6.8 8.7 7.4 8.6 14.2 9.7 6.9 9.9 12.3 12.2 12.9 10.9 13.2 8.6 10.7 9.1 11.4 6.0 7.8 14.5 15.6 8.5 8.8 8.3 7.6 8.5 8.8 15.5 7.4 9.6 8.0 13.0 13.0 18.0 9.2 9.7 4.3 9.4 15.3 10.2 8.7 7.6 10.3 8.0 7.2 12.5 16.8 5.3 10.2 9.4 6.0 10.6 11.3 12.4 24.9 19.1 25.4 29.2 16.0 26.3 24.7 14.3 17.1 12.2 23.7 18.5 11.3 16.5 17.3 10.1 23.8 16.7 17.6 18.1 14.2 15.3 10.2 16.0 23.1 23.6 13.0 20.1 27.2 12.2 12.5 22.6 15.9 22.2 19.9 29.6 24.8 8.2 25.6 8.1 13.2 16.4 10.1 29.7 19.2 12.0 20.7 17.9 11.8 43.6 17.3 17.5 19.3 27.7 17.1 9.7 16.3 32.7 11.6 15.5 27.6 30.8 47.1 23.1 23.9 18.2 25.3 2.3 6.6 8.0 6.6 7.1 7.4 3.2 5.8 7.2 5.6 6.0 5.9 5.9 15.3 7.5 5.7 9.8 7.3 4.4 6.8 7.4 9.7 6.9 6.0 7.8 8.3 7.6 8.0 8.7 7.2 10.6 14.6 28.9 17.7 22.5 13.1 9.2 11.0 30.3 11.4 20.7 14.7 10.5 14.3 7.2 26.4 18.4 18.8 23.2 19.9 17.6 1.9 22.2 3.9 29.0 24.4 14.5 9.1 7.4 20.2 26.5 8.7 15.5 9.2 15.7 19.7 17.8 11.4 27.1 19.0 15.2 15.6 10.9 22.4 16.4 11.0 1.5 13.1 13.8 17.8 19.7 14.1 16.3 9.2 20.6 35.3 25.6 12.9 10.9 21.7 10.3 27.1 15.9 44.9 24.7 6.6 10.0 18.3 26.9 19.1 12.4 11.6 20.1 13.9 10.9 12.0 8.6 ELOC "SIII, TCEB1" ENSG00000154582 "Elongin C" Q15369 8 73939169-73972287 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 266.1;Extravillous trophoblasts: 326.2;Hofbauer cells: 313.7;Pancreatic endocrine cells: 317.3;Proximal tubular cells: 341.3;Syncytiotrophoblasts: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078113 Approved "Nucleoli,Vesicles,Cell Junctions" NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cell Junctions" "HPA078113: AB_2686877" "prognostic unfavorable (6.48e-4)" "unprognostic (1.60e-1)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (8.02e-3)" "unprognostic (5.84e-3)" "unprognostic (2.19e-2)" "unprognostic (1.77e-1)" "unprognostic (6.99e-3)" "unprognostic (4.02e-3)" "unprognostic (3.33e-2)" "unprognostic (2.77e-3)" "unprognostic (3.84e-2)" "unprognostic (5.33e-2)" "unprognostic (1.67e-1)" "unprognostic (8.95e-2)" 78.3 83.9 86.5 45.0 89.6 93.1 59.9 88.6 116.1 47.9 79.8 61.3 30.2 48.1 67.0 75.3 46.2 39.3 141.0 92.5 85.3 97.2 76.0 62.0 52.5 83.6 83.9 46.1 41.1 58.5 57.2 56.0 83.9 45.2 44.8 69.4 46.7 43.7 190.3 48.4 40.7 54.8 84.2 48.2 57.3 111.2 85.1 64.4 43.3 125.6 65.7 69.3 52.0 89.5 211.2 169.2 151.1 110.2 113.0 146.7 108.1 203.6 165.3 194.8 199.0 151.1 178.2 106.3 160.7 181.9 263.4 147.2 168.7 203.6 256.8 123.2 141.5 185.7 174.2 243.0 147.3 120.4 133.6 149.4 159.9 177.0 226.8 144.2 184.8 180.2 166.2 137.8 260.2 155.9 311.7 214.9 137.5 341.9 271.8 111.9 95.1 100.8 216.2 181.9 142.1 134.3 85.2 458.9 202.4 155.1 169.2 127.9 142.2 140.1 160.6 156.1 208.1 155.6 204.5 198.9 169.6 130.2 175.0 138.6 66.4 85.6 62.0 78.6 68.3 83.1 74.2 70.8 73.6 73.9 66.5 67.5 79.8 73.4 77.3 118.4 99.1 60.0 86.5 89.6 88.6 116.1 92.5 85.3 83.6 83.9 83.9 84.2 85.1 89.5 236.0 67.3 98.9 0.0 24.8 0.0 0.0 0.0 0.0 0.0 147.6 185.4 0.0 0.0 49.5 119.5 0.0 220.1 74.5 0.0 266.1 216.7 0.0 147.9 98.9 77.1 0.0 0.0 0.0 227.2 326.2 66.0 0.0 168.8 69.4 65.9 0.0 0.0 313.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.9 0.0 0.0 112.7 0.0 0.0 0.0 0.0 317.3 0.0 0.0 12.1 0.0 0.0 341.3 63.4 0.0 0.0 0.0 78.2 0.0 0.0 0.0 0.0 332.5 40.7 98.8 0.0 0.0 ELP6 "C3orf75, FLJ20211, TMEM103" ENSG00000163832 "Elongator acetyltransferase complex subunit 6" Q0PNE2 3 47495640-47513712 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046358, HPA064545" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" Centrosome "HPA046358: AB_10961011, HPA064545: AB_2685282" "unprognostic (2.00e-3)" "unprognostic (2.27e-1)" "unprognostic (7.41e-3)" "unprognostic (2.41e-2)" "unprognostic (2.67e-1)" "unprognostic (8.62e-2)" "unprognostic (4.24e-3)" "unprognostic (1.66e-1)" "unprognostic (2.11e-2)" "unprognostic (1.24e-2)" "unprognostic (2.07e-2)" "unprognostic (5.38e-2)" "prognostic favorable (3.42e-6)" "unprognostic (1.54e-1)" "unprognostic (9.05e-2)" "unprognostic (2.30e-1)" "unprognostic (6.29e-2)" 13.5 27.0 21.3 14.3 22.8 11.5 15.8 23.6 23.6 14.5 24.3 16.2 15.2 17.2 23.1 15.5 16.9 14.7 19.6 21.0 21.6 17.5 21.3 12.1 21.9 22.8 22.2 21.7 14.8 21.1 15.1 14.4 22.7 19.4 13.9 8.7 16.4 17.7 35.6 16.6 13.4 18.0 22.2 15.7 15.7 21.1 22.9 24.6 19.3 29.0 20.5 16.0 13.3 23.7 37.6 36.4 45.3 46.8 34.9 32.0 26.5 43.4 29.7 54.2 48.6 35.1 38.4 68.7 27.1 37.6 51.3 22.1 43.6 62.5 33.0 39.9 34.4 62.6 55.5 40.4 38.5 49.1 38.5 34.9 33.2 61.4 38.3 31.5 47.3 58.8 67.1 21.7 54.1 44.0 59.8 56.7 55.1 35.4 57.9 29.2 22.3 42.2 38.4 33.9 40.3 40.9 36.9 29.8 25.8 36.0 40.8 41.1 32.8 57.3 41.9 28.9 56.9 44.8 63.5 64.9 28.4 58.8 58.4 19.7 20.4 15.1 31.8 18.9 25.2 33.4 29.4 32.9 25.9 35.2 28.3 28.9 2.8 35.3 13.7 33.9 38.5 25.6 21.3 22.8 23.6 23.6 21.0 21.6 22.8 22.2 22.7 22.2 22.9 23.7 19.3 6.4 12.3 8.8 24.9 8.4 15.2 35.7 19.4 21.7 20.3 22.4 23.0 24.3 20.0 33.1 14.6 44.0 27.8 16.0 60.7 28.1 8.3 15.3 19.4 22.6 17.4 30.3 9.4 23.6 39.6 23.4 17.9 14.0 22.2 56.3 30.0 28.5 28.6 38.7 11.9 15.0 40.7 14.5 8.3 14.5 23.0 17.4 16.0 9.4 21.7 43.7 48.4 5.5 11.7 21.3 12.7 30.5 23.1 10.9 22.9 51.1 15.7 26.0 6.6 14.2 22.6 47.2 22.4 15.6 8.4 26.8 23.9 58.4 21.7 10.4 EMG1 "C2F, Grcc2f, NEP1" ENSG00000126749 "EMG1 N1-specific pseudouridine methyltransferase" Q92979 12 6970913-6997428 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039304, HPA039666" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA039304: AB_2676432, HPA039666: AB_10672891" "unprognostic (1.23e-1)" "unprognostic (1.17e-1)" "unprognostic (6.77e-2)" "unprognostic (1.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (2.70e-1)" "unprognostic (1.03e-1)" "unprognostic (2.12e-1)" "unprognostic (9.03e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (2.83e-6)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (6.75e-2)" "unprognostic (1.62e-1)" 16.8 18.0 13.0 15.2 14.2 12.6 17.3 14.4 20.2 14.9 15.9 14.0 11.1 14.5 13.6 20.2 16.1 4.6 22.6 13.2 14.1 23.2 22.8 15.9 13.4 14.4 14.2 13.9 13.6 9.4 12.8 8.6 14.5 15.7 9.7 9.3 13.6 6.1 21.2 17.4 14.0 7.4 14.3 18.1 14.6 9.9 14.0 12.3 15.6 12.8 12.8 16.1 14.1 15.3 55.5 53.7 20.5 25.2 15.8 11.5 84.7 40.1 17.9 31.2 21.2 106.4 57.6 55.4 14.7 25.1 56.8 39.8 18.9 46.1 35.2 40.1 30.6 76.8 51.7 99.6 20.3 79.0 47.8 18.5 27.2 45.5 51.8 16.2 13.9 38.6 38.6 12.1 29.8 65.3 41.4 48.3 169.6 45.4 28.0 56.3 41.2 44.0 20.0 68.8 11.9 35.7 42.2 43.9 41.4 57.5 12.0 57.8 29.2 32.4 42.6 26.8 92.9 14.6 17.9 97.7 34.8 33.7 52.8 15.5 44.1 22.3 60.7 66.4 63.3 85.3 63.6 67.6 51.2 88.0 74.4 69.1 6.2 60.9 86.4 55.8 68.1 81.3 13.0 14.2 14.4 20.2 13.2 14.1 14.4 14.2 14.5 14.3 14.0 15.3 30.1 16.0 41.3 1.3 34.0 36.6 92.2 79.1 25.0 14.7 29.0 36.8 0.0 24.3 60.9 42.3 8.4 107.3 22.8 18.1 49.0 75.3 9.6 23.1 24.8 32.3 9.6 16.0 1.3 66.8 121.0 31.8 11.7 22.7 60.9 27.7 23.2 35.9 65.4 16.8 1.4 25.7 71.2 25.0 29.3 15.5 37.9 27.7 28.4 1.9 45.1 24.5 43.3 2.0 2.7 75.7 19.8 25.9 17.3 69.0 25.1 81.1 54.0 16.0 39.5 29.2 86.5 28.9 59.7 28.4 39.9 74.3 30.6 46.4 35.7 75.8 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 EMX1 ENSG00000135638 "Empty spiracles homeobox 1" Q04741 2 72916260-72936071 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.1;kidney: 36.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 55.2;Excitatory neurons: 13.0;Proximal tubular cells: 35.7" "Cancer enriched" "Detected in some" 5 "renal cancer: 3.7" "Region enriched" "Detected in some" 10 "cerebral cortex: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.3;CACO-2: 3.7;HEK 293: 8.3;HMC-1: 1.6;RPTEC TERT1: 1.4;U-2 OS: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 17 "amygdala: 2.7;cerebral cortex: 10.5;hippocampal formation: 7.8" "HPA006230, HPA006421" Approved Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA006230: AB_2667542, HPA006421: AB_1078739" "unprognostic (4.54e-2)" "unprognostic (5.59e-2)" "unprognostic (8.71e-2)" "unprognostic (2.22e-6)" "unprognostic (4.82e-2)" "unprognostic (1.70e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (2.99e-1)" "unprognostic (3.07e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-3)" "unprognostic (5.02e-2)" 0.2 0.1 0.1 0.0 1.3 0.0 0.0 0.0 13.1 0.0 0.0 0.4 0.8 0.0 0.7 0.1 0.0 0.0 0.0 1.3 0.0 36.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.9 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 13.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 55.2 0.0 0.1 0.0 1.2 5.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.9 35.7 0.0 0.0 0.0 0.0 0.0 1.5 5.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 EN2 ENSG00000164778 "Engrailed homeobox 2" P19622 7 155458129-155464831 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "brain: 19.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3.6;Glandular and luminal cells: 8.7" "Cancer enhanced" "Detected in many" "melanoma: 6.3" "Group enriched" "Detected in many" 6 "cerebellum: 19.2;midbrain: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.1;AN3-CA: 15.2;HAP1: 9.0;HEK 293: 25.1;SK-MEL-30: 12.9" "Region enriched" "Detected in some" 8 "cerebellum: 27.8" "Region enriched" "Detected in some" 5 "cerebellum: 52.3" "HPA045646, HPA069809" Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" No No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "HPA045646: AB_2679404, HPA069809: AB_2686205" "unprognostic (2.44e-3)" "unprognostic (1.71e-2)" "unprognostic (4.89e-2)" "unprognostic (7.99e-3)" "prognostic unfavorable (1.74e-6)" "unprognostic (2.54e-1)" "unprognostic (8.02e-2)" "unprognostic (7.00e-2)" "unprognostic (1.15e-1)" "unprognostic (9.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.94e-1)" "unprognostic (1.03e-13)" "unprognostic (4.91e-3)" "unprognostic (2.72e-1)" "unprognostic (2.24e-1)" "unprognostic (5.64e-3)" 0.1 0.1 0.1 0.0 0.2 0.0 0.1 19.2 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.2 8.0 0.6 0.3 0.5 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.8 0.7 41.1 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.1 0.0 1.4 0.0 9.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.3 5.5 0.0 0.0 0.0 0.0 2.0 0.0 3.2 0.0 0.1 0.3 0.0 0.0 3.0 0.0 12.9 0.0 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 19.2 0.7 0.2 0.4 0.2 8.0 2.3 0.3 0.9 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 3.6 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 8.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.4 1.5 0.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 ENAH "FLJ10773, MENA, NDPP1" ENSG00000154380 "ENAH actin regulator" Q8N8S7 1 225486835-225653142 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028448, HPA028696" Enhanced Enhanced "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 15000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028448: AB_10600766, HPA028696: AB_10611249" "unprognostic (2.56e-2)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.61e-3)" "unprognostic (2.85e-1)" "unprognostic (1.21e-3)" "unprognostic (2.30e-1)" "unprognostic (2.23e-1)" "unprognostic (9.22e-2)" "unprognostic (4.71e-3)" "unprognostic (2.14e-1)" "unprognostic (2.24e-3)" "unprognostic (8.84e-2)" "unprognostic (5.83e-2)" "unprognostic (7.92e-2)" "unprognostic (2.93e-2)" 26.3 20.2 30.3 16.5 25.9 0.5 13.4 21.1 20.3 13.5 2.0 30.9 12.5 23.6 13.7 16.2 15.0 23.6 25.2 27.2 35.7 7.0 7.5 17.3 4.7 35.5 34.2 22.6 22.3 17.9 6.5 18.2 28.1 21.4 10.1 8.1 20.9 30.6 20.4 10.6 10.8 57.6 22.4 24.8 23.3 25.0 40.9 9.0 7.3 11.5 4.6 30.1 13.8 28.7 91.6 71.9 87.1 79.0 33.3 43.7 111.9 99.1 47.3 58.4 43.9 46.4 33.0 38.7 256.8 153.9 52.5 79.0 102.7 37.4 55.2 0.6 63.4 40.3 62.4 63.1 99.4 4.8 1.5 67.9 44.2 75.9 96.2 47.8 47.0 10.7 2.7 1.9 58.6 17.7 18.5 4.7 146.8 23.9 64.3 27.6 122.9 1.1 26.9 69.5 85.3 68.9 194.6 73.3 63.3 66.1 87.5 5.9 92.2 150.4 109.8 126.8 198.6 4.2 11.4 25.7 82.7 5.0 78.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 30.3 25.9 21.1 20.3 27.2 35.7 35.5 34.2 28.1 22.4 40.9 28.7 117.0 12.8 37.3 81.9 3.8 129.0 172.5 64.4 26.2 11.2 96.2 57.9 119.3 54.3 56.5 22.0 62.6 65.0 1.7 14.8 3.9 84.7 74.8 127.2 60.5 79.3 41.4 0.0 86.3 100.5 18.5 71.6 63.2 75.0 5.1 194.2 23.9 12.9 11.2 16.8 155.0 27.3 26.4 1.6 29.7 24.3 58.1 4.3 83.6 41.2 3.8 32.6 3.1 160.4 151.3 61.5 16.5 168.9 1.6 133.1 3.5 19.6 137.8 19.0 92.1 69.4 166.1 13.4 37.2 25.6 134.1 60.5 4.8 220.7 31.3 100.3 ENKD1 "C16orf48, DKFZP434A1319, FBB11" ENSG00000124074 "Enkurin domain containing 1" Q9H0I2 16 67662945-67667265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 34.2;Endometrial ciliated cells: 38.3;Respiratory ciliated cells: 42.5;Spermatocytes: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041163, HPA041478" Approved Approved "Plasma membrane,Centrosome,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Centrosome" Cytosol "HPA041163: AB_10794986, HPA041478: AB_10794668" "unprognostic (6.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.59e-3)" "prognostic favorable (1.68e-4)" "unprognostic (4.41e-1)" "unprognostic (1.06e-1)" "unprognostic (3.78e-3)" "unprognostic (1.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (5.69e-2)" "unprognostic (6.58e-2)" "unprognostic (1.67e-1)" "unprognostic (2.44e-1)" "unprognostic (3.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" 12.8 12.8 8.4 4.6 8.3 3.5 14.9 22.0 11.5 23.2 13.6 28.6 3.9 21.2 5.6 8.6 30.7 3.6 13.2 8.2 8.6 26.6 11.6 14.7 2.2 9.9 10.9 21.2 67.2 16.0 25.6 3.3 8.4 20.6 2.7 8.5 13.7 9.2 9.5 12.1 11.1 4.4 10.0 11.9 15.9 41.1 9.1 4.7 22.3 1.6 2.5 21.5 14.2 8.5 11.1 7.5 17.2 8.0 5.6 5.8 8.5 8.5 5.1 6.7 8.1 5.5 16.5 4.1 14.3 5.3 0.0 12.7 4.5 10.2 8.2 6.5 10.2 4.1 25.7 13.1 9.1 7.4 5.4 5.1 7.3 9.1 8.2 15.4 5.5 13.3 6.9 2.5 3.5 5.7 8.2 30.9 8.2 11.5 3.0 28.5 1.8 31.3 7.2 1.1 17.4 18.9 18.2 1.8 9.7 3.9 15.8 10.5 14.3 8.1 11.4 15.2 0.1 19.1 9.2 4.5 12.3 10.8 2.5 0.0 0.4 0.0 0.1 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.2 0.3 0.9 0.2 0.2 1.3 0.0 0.1 8.4 8.3 22.0 11.5 8.2 8.6 9.9 10.9 8.4 10.0 9.1 8.5 8.8 22.4 14.4 8.8 1.7 6.9 5.9 6.2 4.0 3.6 10.4 11.2 5.5 10.0 4.0 9.2 4.2 3.1 1.5 4.4 1.9 13.1 34.2 38.3 10.5 8.6 13.2 2.1 2.1 10.7 2.4 7.5 1.5 9.5 1.3 7.4 10.4 26.4 4.7 3.3 2.2 6.0 2.0 3.2 4.3 20.6 13.1 2.6 5.4 0.0 3.0 8.8 0.0 2.5 1.7 9.5 1.4 14.3 2.6 6.0 1.8 7.3 42.5 10.5 6.6 9.1 8.0 37.0 7.9 1.2 5.3 3.4 1.9 11.6 4.9 4.4 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 11 "U-698: 8664.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: AB_2681425" "unprognostic (6.27e-2)" "prognostic favorable (8.24e-4)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (2.58e-1)" "unprognostic (8.24e-2)" "unprognostic (1.94e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (2.21e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.64e-2)" "unprognostic (8.07e-3)" 140.5 106.6 151.2 115.1 156.7 219.8 154.9 133.6 188.2 145.2 132.6 135.9 133.6 117.8 183.3 288.0 100.5 94.9 120.2 161.6 144.1 118.8 148.8 124.0 128.4 137.2 135.6 102.4 108.5 173.0 92.0 103.7 134.2 97.7 123.9 121.8 122.9 94.6 301.0 241.3 132.7 105.8 136.9 99.7 124.1 45.2 147.4 157.8 134.4 212.3 146.7 147.0 165.6 157.0 287.1 170.8 236.9 206.9 149.7 126.8 220.7 141.0 148.4 199.9 171.7 207.3 216.6 288.9 196.8 122.1 125.1 238.3 198.5 325.4 160.1 415.1 277.4 434.3 239.6 158.2 108.3 372.1 462.6 100.5 202.0 214.1 293.6 118.8 206.2 224.8 321.7 551.8 140.9 775.5 302.3 272.6 431.2 386.2 211.1 298.6 199.9 328.0 299.2 306.0 303.8 193.3 201.6 385.6 222.1 200.8 533.9 442.9 208.2 143.9 261.9 171.8 340.3 309.4 441.4 8664.2 197.1 357.6 191.8 67.3 54.4 94.3 55.6 62.9 52.2 64.3 46.3 57.5 70.7 55.3 37.7 56.0 53.0 68.8 64.3 58.3 58.2 75.1 151.2 156.7 133.6 188.2 161.6 144.1 137.2 135.6 134.2 136.9 147.4 157.0 103.1 41.7 166.1 20.9 132.9 190.3 225.1 303.9 124.7 59.7 152.7 117.1 102.6 98.7 172.9 82.8 45.9 286.5 148.9 170.7 254.3 160.3 9.7 109.1 68.5 114.2 130.8 178.2 44.7 152.4 184.2 85.9 71.9 93.7 224.3 51.1 80.3 86.9 203.3 67.3 29.3 169.1 211.6 101.1 171.4 17.7 86.0 123.3 103.2 19.7 409.7 83.6 184.4 21.6 19.3 91.5 146.8 104.2 135.6 128.0 187.2 186.0 128.8 50.0 72.3 85.5 94.4 27.6 25.0 269.7 286.8 382.8 140.4 87.9 163.9 253.7 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 27.6;liver: 14.5" "Group enriched" "Detected in some" 5 "Distal enterocytes: 194.5;Intestinal goblet cells: 181.0;Paneth cells: 174.3;Proximal enterocytes: 167.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;OE19: 1.7;RPMI-8226: 5.3;T-47d: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 1.4 0.0 0.4 0.4 0.2 0.2 0.6 0.0 21.3 27.6 0.1 0.0 0.3 0.7 3.7 0.0 0.0 0.0 3.1 14.5 0.1 0.1 0.2 0.1 0.1 3.1 0.1 5.1 0.1 0.0 0.4 11.2 0.0 6.3 0.2 0.0 0.1 27.2 0.1 0.0 0.2 8.9 0.5 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 5.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.7 0.2 0.0 0.0 5.3 0.7 0.0 0.2 0.5 0.1 0.0 0.1 0.4 2.8 0.1 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 1.7 1.5 0.4 11.5 0.3 20.2 0.0 0.0 0.1 194.5 0.0 1.3 0.0 3.0 0.4 0.1 3.6 0.0 0.0 7.5 0.2 0.1 31.6 4.7 0.0 0.1 0.4 10.1 0.1 0.0 0.0 181.0 8.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 174.3 0.0 0.2 0.6 167.3 5.9 1.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.3 0.1 15.6 1.7 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 86.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 19.4 9.1 7.2 12.8 7.2 5.9 19.5 6.7 10.9 14.0 22.4 25.8 7.4 29.9 9.8 17.5 18.5 17.8 28.5 7.1 7.0 10.2 5.7 28.7 8.2 7.7 7.6 11.6 12.6 5.0 9.3 22.3 8.0 27.9 8.6 8.8 16.4 33.7 20.0 9.7 11.4 25.4 7.8 10.0 15.5 8.9 7.8 11.1 7.9 15.2 8.8 24.7 13.7 7.5 19.0 7.1 12.5 14.4 16.6 32.2 8.6 25.4 31.5 16.0 21.0 9.1 10.2 1.1 3.8 28.1 13.6 6.0 8.3 32.3 19.9 62.3 5.6 20.2 15.5 13.5 18.7 11.5 8.2 26.8 29.4 20.6 25.1 19.4 86.2 0.8 5.9 11.1 53.7 5.5 2.0 3.8 13.5 6.2 3.5 0.8 12.4 8.2 13.9 43.4 1.2 6.3 29.1 1.7 23.5 12.8 6.0 15.9 44.6 40.6 13.4 5.1 24.3 6.0 20.5 9.3 16.3 17.1 23.8 5.4 1.5 0.0 2.0 1.4 2.3 1.1 3.0 4.3 2.4 0.7 2.5 2.7 0.2 2.4 0.5 0.4 6.6 1.3 7.2 7.2 6.7 10.9 7.1 7.0 7.7 7.6 8.0 7.8 7.8 7.5 29.6 12.8 10.3 14.0 3.5 7.1 11.4 13.2 16.5 2.2 7.5 11.7 20.7 4.3 14.5 1.8 16.7 0.9 3.1 5.1 0.0 4.6 16.5 15.3 7.5 23.7 6.0 3.8 11.2 8.2 5.3 9.3 9.2 15.4 0.0 9.4 20.3 3.6 6.7 0.0 21.4 4.5 2.0 6.8 9.8 15.1 3.1 8.6 8.8 30.9 6.5 1.4 1.0 9.5 12.2 12.4 3.4 40.6 5.4 8.3 2.1 1.9 13.2 5.6 0.0 26.8 15.2 5.5 2.5 14.8 4.5 0.8 7.0 6.9 3.4 8.6 EOMES TBR2 ENSG00000163508 Eomesodermin O95936 3 27715949-27722711 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Differentiation, Gastrulation, Immunity, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.4;lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "dendritic cells: 43.6;Erythroid cells: 16.8;NK-cells: 93.7;T-cells: 31.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Region enriched" "Detected in single" 13 "cerebellum: 8.4" "Group enriched" "Detected in many" 7 "gdT-cell: 16.5;MAIT T-cell: 26.2;memory CD8 T-cell: 19.5;naive CD8 T-cell: 11.9;NK-cell: 33.0" "Group enriched" "Detected in many" 107 "NK-cells: 33.0;T-cells: 26.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.4;JURKAT: 8.3;SCLC-21H: 3.9" "Region enriched" "Detected in many" 8 "olfactory bulb: 77.5" "Group enriched" "Detected in some" 27 "cerebellum: 30.2;olfactory bulb: 12.7" HPA028896 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA028896: AB_10601370" "unprognostic (1.53e-4)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.60e-4)" "unprognostic (4.13e-2)" "unprognostic (9.63e-4)" "unprognostic (4.29e-4)" "unprognostic (3.14e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (6.32e-3)" "unprognostic (1.49e-2)" 1.0 0.6 0.2 3.2 0.1 1.8 0.6 8.4 0.4 0.4 0.4 0.7 0.4 0.8 0.8 0.3 0.4 1.6 0.3 0.2 0.3 0.4 2.4 2.2 15.0 0.2 0.3 0.5 0.3 0.1 0.2 0.4 0.6 0.5 0.8 1.6 0.9 0.1 0.1 0.2 1.4 0.4 0.3 12.8 1.3 0.4 0.2 1.5 0.5 0.1 5.4 1.3 0.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 1.3 0.0 7.4 1.1 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.8 0.0 0.9 0.3 0.0 8.3 0.2 0.0 0.0 2.0 2.0 0.0 0.2 0.2 0.9 1.3 0.0 0.0 0.6 0.0 3.9 0.0 0.0 0.0 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 16.5 0.0 26.2 0.0 3.0 19.5 0.0 0.0 0.2 11.9 0.2 33.0 0.1 0.1 0.0 2.9 0.2 0.1 8.4 0.4 0.2 0.3 0.2 0.3 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.8 1.5 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 16.8 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 2.2 1.6 0.2 0.0 0.0 0.0 0.0 3.1 0.7 0.0 0.3 1.3 1.8 1.0 1.1 0.1 93.7 0.0 0.0 0.0 0.0 0.4 9.8 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 2.0 0.0 0.1 0.0 31.5 0.0 0.0 0.0 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 49.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.0;Basal prostatic cells: 7.3;Basal squamous epithelial cells: 25.6;Urothelial cells: 5.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTCEpi: 157.9;U-2197: 74.8" "Not detected" "Not detected" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" 1.6 0.1 0.2 1.6 0.1 0.3 1.4 0.4 0.6 5.2 0.1 0.1 0.1 0.0 1.1 49.0 1.5 0.1 0.8 0.2 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.1 0.1 2.2 0.1 0.5 0.1 0.2 0.0 0.2 3.6 3.1 0.1 3.5 0.1 0.0 0.1 0.3 0.0 1.1 0.1 0.9 0.0 0.0 3.4 1.3 9.6 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.1 1.8 0.2 3.6 0.0 2.8 0.0 0.0 0.0 0.5 20.2 0.0 0.2 0.0 0.7 0.0 157.9 2.9 11.7 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.0 0.0 0.3 0.0 3.6 0.4 0.0 0.0 0.3 0.3 0.1 0.0 8.3 3.3 0.0 0.0 0.5 0.0 0.2 0.4 0.1 74.8 0.2 0.0 0.0 0.1 0.7 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.3 0.1 0.7 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.4 0.0 0.0 1.5 0.0 0.0 6.0 7.3 0.9 25.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 3.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 3.0 1.6 0.1 0.2 0.0 0.0 5.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;dendritic cells: 53.7;Early spermatids: 42.2;Excitatory neurons: 47.9;Inhibitory neurons: 44.3;Late spermatids: 41.2;Oligodendrocyte precursor cells: 77.9" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Group enriched" "Detected in some" 5 "HDLM-2: 63.9;HMC-1: 35.5;RPTEC TERT1: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 1.0 0.6 4.7 0.8 18.7 0.7 3.2 40.6 12.8 1.8 0.0 3.2 1.4 2.2 0.9 1.9 1.3 1.7 0.3 7.0 5.1 1.3 1.6 0.3 1.9 5.0 14.4 0.7 0.3 0.2 1.0 0.2 5.5 1.7 0.5 4.2 2.2 2.7 4.9 4.8 0.7 0.7 0.9 1.9 0.6 10.8 12.0 0.7 7.0 10.3 1.7 1.5 1.0 4.2 0.0 0.0 8.4 0.1 0.2 0.0 0.0 6.6 0.1 0.3 0.1 0.1 0.0 1.1 1.6 3.4 0.6 0.1 5.5 0.0 1.2 63.9 0.8 4.8 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.3 0.2 0.5 0.0 0.3 4.7 0.2 0.0 0.3 2.4 1.2 0.1 0.0 0.9 0.2 16.5 0.0 1.1 0.2 0.0 0.1 0.0 1.1 0.1 0.7 0.5 1.1 3.4 0.7 7.9 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 23.3 0.0 0.2 4.7 18.7 40.6 12.8 7.0 5.1 5.0 14.4 5.5 0.9 12.0 4.2 1.9 0.0 0.0 198.8 1.0 3.7 0.0 0.0 0.0 1.9 0.8 12.3 1.6 0.0 0.0 0.0 10.4 0.0 53.7 0.0 0.0 0.8 42.2 0.1 0.5 2.8 0.0 0.0 47.9 0.4 0.1 0.4 0.0 0.1 0.0 3.3 0.4 7.0 0.4 0.0 44.3 0.0 0.0 0.0 0.8 41.2 0.6 0.8 1.8 8.4 0.1 16.9 0.0 77.9 5.6 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.3 0.8 0.5 1.6 0.0 5.8 0.0 0.2 3.0 0.3 0.2 EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 387.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 263.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" 57.1 75.3 63.1 27.3 61.2 22.1 53.0 30.3 82.2 51.1 14.8 73.1 88.7 47.8 9.2 80.5 48.7 14.3 148.6 65.2 31.5 85.2 137.1 50.5 19.3 37.8 38.5 76.2 104.3 22.3 51.1 17.4 31.1 64.8 16.2 8.9 50.9 20.0 156.1 71.0 80.4 11.0 27.9 72.8 152.6 80.8 40.0 11.6 49.0 35.3 11.2 50.1 54.5 47.1 95.5 128.8 31.5 64.8 35.6 33.8 64.6 69.3 39.0 48.2 48.0 54.1 58.7 58.1 46.1 55.6 42.5 71.5 27.7 52.9 17.4 20.4 263.2 42.8 67.4 65.3 48.9 27.8 39.3 43.9 45.6 41.7 30.1 34.7 46.4 40.7 64.7 48.0 32.2 53.6 44.4 45.2 72.3 71.4 179.6 29.5 42.8 103.2 36.8 55.3 45.2 109.9 64.1 68.8 48.0 21.7 51.6 95.7 78.4 133.0 63.8 48.4 101.3 52.2 50.9 41.7 97.9 55.0 67.5 1.4 1.8 2.3 0.6 2.2 0.4 1.0 0.6 0.6 1.1 0.8 0.6 0.6 2.1 0.3 3.6 1.7 0.9 1.5 63.1 61.2 30.3 82.2 65.2 31.5 37.8 38.5 31.1 27.9 40.0 47.1 62.6 3.2 20.4 9.8 44.2 31.4 29.0 25.9 44.3 33.3 32.7 25.8 15.5 55.8 17.9 44.1 66.7 46.1 28.1 227.7 119.3 57.1 63.2 39.5 37.5 46.1 45.0 35.3 7.8 88.5 80.8 37.2 145.2 45.9 10.8 87.0 83.9 106.1 62.9 28.6 7.8 115.6 22.4 136.5 21.4 169.4 47.5 55.4 23.2 6.5 40.8 33.6 28.8 4.5 8.9 106.5 167.7 53.0 57.7 37.6 387.2 81.8 20.9 41.3 13.1 41.2 34.6 50.2 62.7 46.6 27.4 52.3 26.3 48.2 132.5 39.2 EPOP "C17orf96, LOC100170841, PRR28" ENSG00000273604 "Elongin BC and polycomb repressive complex 2 associated protein" A6NHQ4 17 38671703-38674957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4;testis: 10.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 19.3;Breast myoepithelial cells: 13.6;Glandular and luminal cells: 6.4;Syncytiotrophoblasts: 13.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.5;basal ganglia: 8.8;cerebral cortex: 10.4;hippocampal formation: 7.7;white matter: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 47.9;Hep G2: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055190, HPA056555" Enhanced Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA055190: AB_2682731, HPA056555: AB_2683172" "unprognostic (9.08e-2)" "unprognostic (3.71e-1)" "unprognostic (5.79e-2)" "unprognostic (6.75e-3)" "unprognostic (1.83e-1)" "unprognostic (1.84e-2)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (2.63e-2)" "unprognostic (1.78e-10)" "unprognostic (8.97e-2)" "unprognostic (2.51e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" 1.6 2.2 4.5 1.7 8.8 0.5 1.1 0.9 10.4 0.9 0.5 0.8 0.3 1.2 0.8 1.9 1.1 0.9 1.2 7.7 0.9 1.6 3.8 1.1 2.7 1.4 1.7 0.8 3.7 4.8 0.8 1.3 1.6 1.4 0.4 2.2 0.8 0.9 0.6 3.3 0.9 0.7 1.3 1.1 1.3 10.0 1.7 1.5 0.6 0.3 3.5 2.9 0.7 5.4 9.2 10.8 6.8 47.9 1.5 0.4 11.7 1.9 0.7 2.1 3.3 10.8 3.3 17.1 11.6 1.2 6.1 7.3 22.6 4.6 3.7 18.2 17.1 3.8 1.5 57.3 3.1 2.1 9.0 1.0 8.0 2.3 4.6 4.4 1.6 18.8 12.0 25.9 1.4 14.4 15.8 5.1 1.5 6.0 9.6 37.3 3.9 37.8 1.3 2.4 10.4 15.8 6.0 7.8 2.1 11.0 11.4 7.2 2.7 2.0 2.0 2.2 1.8 13.5 16.1 21.7 3.9 25.4 7.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 8.8 0.9 10.4 7.7 0.9 1.4 1.7 1.6 1.3 1.7 5.4 4.4 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 19.3 13.6 0.0 0.0 1.3 1.8 0.0 1.7 3.5 0.0 0.0 4.2 0.0 3.4 4.8 1.8 0.0 0.0 0.0 4.0 1.5 1.0 0.0 6.4 0.0 1.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 13.1 0.6 0.8 0.0 0.0 ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 72.8;Inhibitory neurons: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 30000000 "Cluster 34: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: AB_2677946" "unprognostic (2.33e-3)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.38e-1)" "unprognostic (1.88e-3)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-2)" "unprognostic (4.52e-2)" "unprognostic (3.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (5.14e-2)" 51.5 15.8 3.7 37.0 4.3 27.9 25.5 3.1 5.6 21.8 2.3 37.9 63.4 22.0 14.4 13.2 25.5 23.7 17.1 3.4 5.2 16.4 32.9 31.2 38.2 8.4 5.7 20.7 13.7 19.1 8.2 47.0 7.0 18.6 43.7 12.4 19.3 22.0 20.9 36.5 55.1 21.7 5.0 30.8 33.7 9.1 6.6 63.7 17.5 19.6 36.8 27.3 11.7 6.8 25.9 14.1 21.3 20.0 114.7 111.5 61.4 18.3 59.6 44.0 76.2 17.6 91.1 75.3 37.6 36.0 61.8 25.7 17.8 38.1 27.3 139.8 7.5 24.7 10.0 13.9 130.9 12.0 44.1 46.8 16.2 50.6 15.5 64.3 61.1 48.8 12.9 74.7 26.7 11.6 113.2 12.4 10.6 3.1 10.4 82.4 28.8 38.4 32.8 39.0 7.8 5.5 29.6 19.8 28.6 14.6 17.1 57.0 48.8 37.4 12.6 6.2 31.1 26.9 53.9 57.8 40.2 40.2 22.5 28.8 15.2 18.0 22.6 12.3 20.2 14.8 19.2 19.1 10.5 18.3 22.3 18.1 15.8 23.1 20.6 16.7 13.9 13.7 3.7 4.3 3.1 5.6 3.4 5.2 8.4 5.7 7.0 5.0 6.6 6.8 11.1 9.6 16.3 34.0 15.3 25.0 14.2 19.2 8.6 13.6 6.6 3.9 10.6 10.0 16.9 9.2 2.1 9.6 21.1 24.4 0.0 12.4 27.0 12.7 15.0 16.3 10.3 14.1 72.8 15.5 11.9 18.4 16.3 19.8 15.2 13.9 16.8 28.0 17.6 3.3 79.3 23.9 4.1 29.9 16.1 7.3 9.9 22.9 7.2 24.4 32.5 9.0 20.6 32.6 70.1 12.3 14.1 16.1 32.3 13.5 47.3 6.9 23.1 7.6 0.0 10.3 22.6 1.4 1.8 9.8 11.1 9.2 21.8 5.7 27.3 14.9 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ERCC4 "FANCQ, RAD1, XPF" ENSG00000175595 "ERCC excision repair 4, endonuclease catalytic subunit" Q92889 16 13920154-13952348 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 140.7;Late spermatids: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000156, HPA045828" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB000156: , HPA045828: AB_2679463" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.12e-3)" "unprognostic (9.41e-2)" "unprognostic (3.35e-1)" "unprognostic (1.40e-2)" "unprognostic (1.64e-2)" "unprognostic (2.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (8.49e-2)" "unprognostic (5.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (5.88e-4)" 2.7 3.9 4.7 3.3 5.2 2.5 2.8 6.7 5.4 3.3 4.3 1.9 1.7 3.3 2.8 2.9 3.5 3.0 3.6 4.3 4.9 2.9 3.2 2.7 3.3 5.1 4.8 4.3 2.7 3.9 1.6 2.6 4.9 3.6 2.2 4.1 2.8 2.9 18.5 3.0 1.9 3.6 4.4 3.7 2.6 5.5 5.4 4.2 4.4 3.3 2.9 2.6 1.5 6.8 4.7 5.5 5.3 7.5 8.7 8.1 4.0 6.1 6.4 5.4 6.8 2.1 4.5 7.8 8.6 5.4 4.8 5.8 8.0 4.1 8.3 10.7 4.7 3.8 6.7 5.2 7.9 5.2 4.2 6.1 5.7 7.1 6.0 5.3 7.2 4.6 6.1 8.8 7.6 3.9 7.0 3.4 3.9 2.4 3.1 7.8 10.8 9.7 3.3 3.2 4.3 5.1 7.5 6.0 5.8 4.2 7.5 3.9 7.9 7.8 5.7 7.0 5.4 7.9 9.9 5.2 7.6 6.2 8.1 4.9 2.3 2.3 2.6 2.7 2.9 2.5 2.4 2.0 2.3 3.1 2.4 2.6 2.7 3.6 2.4 3.2 2.5 1.1 4.7 5.2 6.7 5.4 4.3 4.9 5.1 4.8 4.9 4.4 5.4 6.8 14.0 19.2 13.5 16.6 11.3 4.8 6.1 18.3 10.2 0.0 10.0 9.5 8.6 14.3 12.7 5.5 0.0 17.3 9.7 3.3 9.8 11.6 140.7 18.6 19.0 13.5 9.6 12.0 20.4 8.4 6.2 13.0 5.1 7.4 1.3 17.8 17.2 17.7 11.7 0.0 21.2 4.8 10.2 13.6 6.5 117.9 14.9 11.4 10.6 8.4 14.4 0.0 17.5 12.1 20.1 9.9 1.7 21.1 14.4 10.2 4.4 13.3 26.1 0.0 26.3 17.3 12.2 49.4 28.9 9.2 5.5 12.3 11.8 18.0 6.0 4.7 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;lymphoid tissue: 3.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.4;Granulosa cells: 2.5;Spermatocytes: 2.1;Spermatogonia: 2.4;Squamous epithelial cells: 2.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Nucleoplasm, Cytosol" "HPA050492: AB_2681145" "prognostic unfavorable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.1 0.1 0.1 1.3 0.2 3.2 0.4 0.8 0.2 0.4 0.1 0.9 0.7 0.2 0.2 1.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 2.3 0.1 0.0 0.3 0.1 0.0 0.1 0.5 0.1 0.1 1.1 0.5 0.3 0.0 0.1 0.6 0.6 0.3 0.0 0.5 0.7 0.8 0.2 3.6 0.1 0.0 2.7 0.2 0.4 0.6 19.0 16.3 14.6 9.3 1.0 1.7 8.0 19.8 9.1 17.0 17.7 13.3 11.6 30.5 7.3 7.2 23.0 15.2 27.8 14.8 30.1 17.5 20.2 10.5 5.5 7.9 0.0 20.7 14.2 0.2 0.9 23.7 4.4 2.8 9.6 15.1 14.1 7.3 17.6 14.8 19.8 12.1 26.6 18.3 24.8 16.4 26.2 5.4 4.4 11.5 12.0 8.6 14.7 9.8 3.6 11.8 7.5 4.6 6.0 11.4 18.3 21.8 13.1 5.7 9.4 25.9 8.1 14.1 11.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 1.7 0.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.9 0.3 0.2 0.5 0.0 0.0 0.3 0.6 0.5 1.5 0.2 0.0 0.0 1.1 0.9 0.6 0.0 0.0 0.3 0.9 0.8 0.3 0.0 3.4 0.9 0.0 1.7 0.5 0.0 0.5 0.0 2.5 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.4 2.1 2.4 2.4 0.1 0.4 0.3 0.2 0.9 0.1 ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 383.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: AB_2680855" "unprognostic (1.62e-2)" "unprognostic (3.50e-2)" "unprognostic (5.53e-2)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.19e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (3.70e-2)" "unprognostic (2.32e-2)" "prognostic favorable (8.18e-4)" "prognostic unfavorable (7.02e-6)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.19e-2)" "unprognostic (2.64e-1)" 38.5 32.5 22.7 37.8 24.6 10.5 46.0 25.1 29.0 34.4 20.8 37.1 34.4 34.4 50.1 46.0 24.2 33.1 52.4 22.6 25.9 30.6 47.6 26.3 33.8 24.9 23.9 26.9 40.2 47.2 20.7 53.1 24.3 39.5 33.7 29.4 49.2 34.5 33.8 19.2 34.9 39.3 25.4 26.7 32.6 57.8 24.4 35.0 45.1 47.0 43.6 50.1 22.1 34.4 96.7 87.0 69.1 46.8 94.8 111.5 170.1 153.1 123.4 92.7 98.3 115.7 157.6 51.3 149.1 120.7 168.7 98.7 66.0 98.3 146.4 112.6 69.4 84.0 114.6 68.3 55.7 121.2 70.0 79.1 75.9 115.8 116.7 169.3 71.8 69.8 70.5 144.6 122.6 52.3 60.3 126.2 98.9 101.3 235.0 54.9 189.9 107.6 75.5 140.1 26.5 43.2 77.2 86.5 91.5 145.9 168.0 96.7 81.8 124.1 108.1 169.1 167.6 106.4 145.5 106.0 103.7 87.3 105.3 92.3 50.2 70.6 84.7 79.9 102.9 83.2 107.6 101.2 55.1 71.0 106.6 90.3 181.1 72.1 101.1 120.9 130.8 90.1 22.7 24.6 25.1 29.0 22.6 25.9 24.9 23.9 24.3 25.4 24.4 34.4 54.6 28.9 28.6 20.9 74.3 57.9 68.9 144.1 39.9 54.8 57.2 55.1 61.7 38.6 99.0 53.3 54.2 119.2 60.8 19.4 49.0 72.7 383.0 48.7 66.5 43.7 41.8 44.8 39.2 62.8 120.6 73.0 25.5 54.6 55.8 44.2 34.6 50.2 56.4 48.8 37.8 33.5 87.5 25.5 40.2 51.9 52.5 37.1 62.2 14.0 41.6 69.5 52.5 32.2 48.3 58.1 20.5 59.8 154.0 85.7 32.4 49.5 64.6 60.0 32.9 58.5 105.7 75.0 36.3 49.4 66.3 156.2 68.0 54.0 34.7 78.8 ERICH1 ENSG00000104714 "Glutamate rich 1" Q86X53 8 614746-738106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003725 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA003725: AB_1853023" "unprognostic (7.19e-2)" "unprognostic (1.38e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-2)" "unprognostic (1.02e-1)" "unprognostic (7.51e-3)" "unprognostic (1.55e-1)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (5.11e-2)" "unprognostic (1.27e-1)" "unprognostic (8.63e-2)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" 15.9 8.7 7.3 17.2 6.5 23.0 13.7 6.4 8.2 10.7 8.3 11.0 8.4 10.1 6.6 10.4 10.5 9.1 10.7 6.9 7.1 22.5 11.6 14.6 21.1 9.0 7.1 11.6 9.0 7.9 11.5 10.1 8.4 9.1 7.2 5.1 9.8 5.8 10.8 13.0 12.4 7.9 6.0 15.3 10.5 8.0 8.4 11.8 13.2 5.5 10.7 12.7 11.6 7.1 15.8 22.2 11.7 14.0 12.4 15.0 24.3 14.9 7.9 13.3 14.6 14.4 9.9 36.0 6.9 12.5 25.3 26.0 21.7 22.9 9.4 15.7 28.1 25.1 15.1 20.8 13.9 15.5 22.6 17.4 14.5 10.1 13.0 13.7 14.7 31.2 26.3 20.2 13.5 13.2 30.0 27.5 18.6 17.6 9.9 27.0 7.6 25.0 14.9 28.7 5.4 15.0 10.9 13.8 20.2 19.2 5.8 18.4 23.7 9.7 4.6 0.6 16.2 13.1 36.7 38.9 19.9 24.6 10.5 24.7 33.0 12.5 8.4 32.3 7.5 17.9 9.7 8.4 17.1 20.1 8.1 7.1 30.0 12.3 29.8 12.7 7.5 10.4 7.3 6.5 6.4 8.2 6.9 7.1 9.0 7.1 8.4 6.0 8.4 7.1 71.0 44.8 36.1 17.9 75.3 36.6 47.0 47.9 32.5 23.3 32.6 32.5 23.0 27.1 31.2 33.1 12.5 62.0 55.4 49.2 109.5 38.4 16.1 35.9 52.2 65.8 19.7 43.9 24.4 36.6 60.4 40.7 66.8 57.4 41.1 48.3 62.4 31.9 41.9 48.8 21.0 50.4 32.6 70.9 68.0 9.2 60.3 69.9 35.6 23.4 126.9 18.2 78.2 11.1 22.5 55.4 54.3 40.6 34.6 51.5 33.3 58.9 26.9 22.1 39.5 33.6 35.6 48.5 58.4 23.2 40.9 54.0 68.3 27.0 39.8 37.0 ERICH5 "C8orf47, FLJ39553" ENSG00000177459 "Glutamate rich 5" Q6P6B1 8 98064522-98093610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 34.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 100.1;Ductal cells: 57.6;Endometrial ciliated cells: 27.8;Proximal tubular cells: 24.5;Respiratory ciliated cells: 39.4" "Cancer enhanced" "Detected in many" "liver cancer: 23.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 2.2" "Lineage enriched" "Detected in single" 11 "dendritic cells: 2.2" "Cell line enhanced" "Detected in some" "A549: 7.3;HAP1: 8.0;HEK 293: 11.5;JURKAT: 14.7;RPTEC TERT1: 7.5;RT4: 18.2" "Not detected" "Not detected" "HPA025070, HPA025293, HPA027233" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA025070: AB_1845778, HPA025293: AB_1845779, HPA027233: AB_1845780" "unprognostic (2.88e-3)" "unprognostic (1.49e-1)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (6.86e-2)" "unprognostic (2.39e-1)" "unprognostic (8.66e-2)" "unprognostic (1.57e-1)" "unprognostic (4.66e-1)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (5.73e-1)" "prognostic favorable (3.76e-4)" "unprognostic (4.36e-2)" "unprognostic (9.22e-2)" "unprognostic (3.17e-2)" "prognostic favorable (9.38e-4)" 0.5 0.1 1.5 0.3 2.4 0.0 1.0 0.9 1.4 2.5 1.2 1.9 5.3 1.3 0.6 0.7 11.1 12.3 5.3 1.0 2.4 5.6 10.2 0.9 1.0 1.8 2.1 0.9 34.2 2.2 1.3 0.2 1.9 2.7 3.3 2.3 1.3 2.3 0.0 0.7 1.5 0.5 1.1 0.2 12.6 2.4 4.7 0.7 0.6 0.0 0.7 1.9 0.5 1.3 0.0 7.3 0.0 0.0 0.1 0.0 4.7 4.6 1.8 2.3 1.8 0.1 2.4 0.0 6.0 1.2 3.6 0.4 8.0 0.2 2.8 0.0 11.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.3 0.0 14.7 0.0 0.0 0.1 0.2 0.0 0.8 1.6 0.2 2.8 0.0 0.0 0.2 7.5 18.2 4.1 0.2 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 2.4 0.9 1.4 1.0 2.4 1.8 2.1 1.9 1.1 4.7 1.3 0.0 3.2 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.2 2.1 1.3 8.0 100.1 3.1 7.3 0.0 0.3 0.0 1.6 0.0 57.6 0.3 27.8 0.6 0.8 18.0 0.0 1.1 18.4 1.8 0.2 7.7 7.7 0.0 4.3 0.4 2.6 0.1 0.0 1.6 2.4 0.0 0.3 0.0 0.0 0.3 0.7 0.0 0.0 0.1 8.0 0.0 0.5 0.1 14.8 1.6 0.0 0.0 2.5 0.7 24.5 39.4 0.1 0.0 0.2 1.0 0.2 4.7 1.1 0.0 0.1 0.2 0.7 3.6 2.6 ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.0" "Cell type enriched" "Detected in some" 56 "Syncytiotrophoblasts: 575.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 38.8" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" 0.3 0.4 0.6 0.1 0.4 0.2 0.4 1.8 0.6 0.4 0.0 0.3 0.5 0.3 1.0 0.3 0.2 0.4 0.1 0.6 0.7 0.5 0.2 0.6 0.0 0.6 0.4 0.0 0.0 7.5 0.0 37.0 0.5 0.3 0.2 0.2 0.2 0.2 0.0 0.5 0.5 0.2 0.1 0.0 0.3 0.1 0.6 0.4 0.0 0.4 0.0 0.5 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.4 1.8 0.6 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 10.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 575.5 0.4 0.5 0.0 0.0 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 569.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" 123.8 87.5 83.0 73.0 85.5 95.1 146.7 86.3 110.8 141.0 87.7 125.7 106.7 129.7 160.1 93.6 121.8 96.4 151.5 84.3 98.6 194.4 277.2 92.3 93.5 87.3 85.6 179.0 67.3 109.9 81.5 81.9 89.7 112.5 135.0 122.0 92.8 140.3 149.8 83.3 93.4 166.2 94.3 63.9 83.0 54.2 82.4 155.7 155.0 179.0 110.3 104.9 96.2 100.0 138.4 77.9 229.8 160.4 264.5 441.9 62.5 190.8 280.9 264.7 204.6 131.6 162.8 156.5 56.9 233.3 194.0 137.1 256.8 227.2 333.0 180.4 270.4 200.3 70.7 208.6 220.5 400.1 82.2 304.6 207.0 167.9 229.4 316.2 253.2 260.3 200.3 40.7 433.5 135.1 352.7 260.0 59.8 175.2 148.8 277.1 133.6 106.2 378.4 55.4 115.0 130.1 85.0 72.6 160.3 157.6 137.1 223.0 169.2 94.4 113.0 187.5 181.8 27.6 63.5 135.7 205.3 223.2 131.2 35.0 129.4 55.7 48.5 113.6 80.9 104.1 97.6 76.3 142.8 83.4 114.1 90.5 15.0 109.3 106.1 170.7 90.6 100.3 83.0 85.5 86.3 110.8 84.3 98.6 87.3 85.6 89.7 94.3 82.4 100.0 139.0 54.5 56.8 37.5 77.2 134.1 227.4 300.5 148.0 51.5 114.1 123.2 99.2 167.3 111.7 154.5 41.7 160.4 51.2 59.1 360.0 168.0 135.5 102.2 120.6 112.5 108.8 99.5 22.7 103.2 141.0 162.9 51.0 80.7 96.4 71.1 132.1 154.7 227.5 21.9 19.3 114.6 175.0 140.2 148.0 34.8 267.8 108.2 165.4 25.3 144.3 199.5 36.0 23.6 36.2 85.4 92.3 211.4 35.9 99.1 137.1 569.1 94.2 77.3 151.2 196.0 484.2 61.6 46.3 120.6 129.3 74.4 78.2 151.2 199.8 143.6 ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 159.2;Hepatocytes: 266.3;Proximal enterocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" 27.3 35.5 25.5 15.8 29.8 16.3 23.6 36.4 31.4 17.5 33.6 67.6 81.8 15.5 4.7 62.7 14.6 10.2 154.9 23.5 31.6 70.3 91.5 30.9 11.0 30.9 31.7 8.1 56.3 23.9 15.9 15.4 29.8 26.4 22.9 5.1 48.5 12.6 195.3 35.9 65.4 7.1 26.6 32.0 52.4 8.4 37.5 8.4 28.3 88.8 12.4 31.0 28.8 23.7 25.9 40.2 9.8 23.6 13.0 12.7 54.2 25.0 11.9 9.2 9.0 37.4 30.3 34.9 45.1 12.8 23.7 66.0 16.9 33.0 3.5 23.0 21.0 22.9 51.7 30.1 18.0 39.3 55.3 17.4 49.8 20.7 27.0 12.8 12.8 18.1 37.9 18.7 15.3 57.9 19.4 55.9 27.9 30.4 74.4 20.4 19.7 79.6 31.1 52.4 20.6 26.2 12.8 81.2 83.8 5.5 25.8 38.2 28.9 16.6 20.4 47.4 25.6 28.6 25.5 23.6 26.9 38.2 13.4 0.2 2.9 4.8 2.7 5.4 2.6 1.7 2.3 1.9 2.7 2.3 2.3 3.3 5.3 1.8 5.1 2.1 3.6 1.7 25.5 29.8 36.4 31.4 23.5 31.6 30.9 31.7 29.8 26.6 37.5 23.7 20.8 9.6 22.7 21.2 14.7 18.6 41.0 29.7 18.8 28.8 30.9 24.3 9.2 100.1 21.3 20.2 33.3 103.8 20.9 159.2 54.8 51.3 3.4 18.7 17.4 15.3 37.8 19.4 13.6 80.2 61.3 12.4 39.8 20.3 7.6 9.3 35.0 266.3 33.6 33.7 16.6 82.5 28.5 82.7 11.7 1.1 6.5 22.2 17.8 11.2 28.8 20.1 27.8 9.0 6.4 81.1 103.1 12.0 8.2 42.8 199.7 82.2 19.8 20.4 13.1 18.7 21.7 3.5 7.1 26.3 18.5 134.2 14.5 22.2 113.7 65.0 ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 299.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: AB_2668349, HPA029407: AB_2673026" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.75e-4)" 10.1 14.4 13.7 14.5 15.2 12.2 13.7 9.0 15.9 10.8 16.4 27.2 23.3 10.2 19.6 10.8 10.1 14.0 7.3 14.7 28.1 18.4 18.2 12.6 17.4 12.0 14.2 11.7 10.7 10.8 13.7 11.3 15.8 10.9 15.3 18.2 12.4 6.2 6.2 15.3 15.5 7.6 11.1 16.7 45.0 17.8 19.3 23.1 14.5 5.6 14.3 10.8 9.5 17.5 14.8 27.9 30.4 27.5 21.2 21.3 21.7 15.6 12.2 17.4 16.0 20.6 33.3 41.1 14.7 11.6 16.5 10.7 27.1 7.6 28.2 36.8 23.7 34.7 11.5 18.9 20.6 33.9 29.4 13.7 7.2 21.9 17.4 25.8 20.3 15.7 41.8 17.2 22.3 7.7 38.8 67.1 59.3 17.9 20.1 32.7 28.1 32.9 25.6 16.5 9.8 17.8 18.9 13.9 27.1 41.1 24.1 32.1 17.5 12.2 19.9 18.6 25.0 12.9 18.1 46.8 16.2 21.0 23.9 44.0 14.3 15.9 15.4 22.0 15.2 22.2 16.4 14.4 14.1 15.3 17.7 17.7 14.6 17.7 23.4 12.6 20.5 19.2 13.7 15.2 9.0 15.9 14.7 28.1 12.0 14.2 15.8 11.1 19.3 17.5 33.6 48.1 32.2 48.0 55.9 144.3 75.7 34.7 64.9 41.0 56.8 42.2 10.1 45.8 43.8 44.1 50.1 30.1 57.6 116.1 27.4 30.7 299.0 64.2 49.1 34.8 108.3 48.8 104.4 44.5 24.2 38.2 230.4 51.4 34.8 40.9 28.2 41.5 42.9 26.9 104.3 60.7 46.8 88.3 60.0 43.5 24.2 57.0 67.6 84.3 39.1 17.7 43.3 121.2 152.9 39.5 62.9 21.4 63.7 73.8 57.7 33.2 81.6 39.5 39.5 23.3 38.9 49.1 18.5 51.9 170.2 75.4 49.0 41.5 47.8 90.3 ETS2 ENSG00000157557 "ETS proto-oncogene 2, transcription factor" P15036 21 38805183-38824955 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 701.0;Basal squamous epithelial cells: 863.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 33.6;granulocytes: 37.0;monocytes: 32.4" "Cell line enhanced" "Detected in many" "HEL: 309.0;hTCEpi: 269.6;hTERT-HME1: 210.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003176 Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA003176: AB_2666824" "unprognostic (2.06e-1)" "unprognostic (5.91e-2)" "unprognostic (9.16e-3)" "unprognostic (5.33e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-3)" "unprognostic (7.36e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.89e-1)" "unprognostic (8.10e-2)" "unprognostic (7.10e-2)" 109.9 29.7 51.4 95.5 43.3 167.1 87.7 31.6 72.5 89.6 61.4 119.3 131.3 77.5 27.9 90.6 72.5 132.1 68.0 50.9 43.2 66.1 230.7 185.5 38.0 50.0 39.9 65.7 37.5 61.9 56.6 73.6 45.0 80.1 146.5 7.5 50.3 45.7 149.7 248.3 179.7 78.0 47.9 201.0 72.7 7.6 54.0 43.7 62.5 42.8 34.8 210.2 103.6 44.4 120.1 26.2 16.6 5.6 18.8 61.3 49.2 27.4 154.1 36.2 46.5 23.0 35.1 24.7 13.3 25.0 48.5 35.7 28.0 71.2 63.8 24.5 12.0 309.0 152.6 62.2 196.9 18.4 28.2 39.8 269.6 49.6 210.2 22.0 28.3 17.2 31.3 0.2 14.4 20.1 54.1 22.2 56.0 39.3 18.2 189.6 10.2 25.2 50.2 74.4 14.2 18.4 78.4 32.8 6.2 5.7 1.9 36.3 30.8 83.0 13.0 55.3 60.5 0.5 0.3 25.2 20.7 69.4 70.8 21.0 19.5 7.0 3.2 24.9 3.9 0.4 3.0 4.7 33.6 0.4 3.2 3.2 37.0 0.3 32.4 8.1 0.3 8.9 51.4 43.3 31.6 72.5 50.9 43.2 50.0 39.9 45.0 47.9 54.0 44.4 253.0 51.3 156.6 6.2 10.8 427.4 701.0 150.8 863.4 2.1 84.2 69.7 25.6 51.5 141.9 51.5 0.0 58.4 17.5 150.7 11.7 73.7 4.0 241.1 127.4 312.7 91.8 36.4 39.6 108.5 109.3 98.7 161.1 497.9 51.3 0.9 242.0 262.4 62.1 0.0 10.7 266.0 79.3 150.8 291.7 2.0 18.0 253.4 67.6 74.0 41.0 1.5 3.1 4.0 3.1 127.6 175.1 24.8 21.0 184.0 162.2 47.2 107.9 1.6 52.6 81.8 108.8 0.6 3.3 522.6 486.4 177.6 28.8 8.2 243.3 338.7 EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.6;Basal squamous epithelial cells: 12.0;Fibroblasts: 8.9;Leydig cells: 11.5;Skeletal myocytes: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.7;HHSteC: 13.0;hTERT-HME1: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Microtubules, Cytokinetic bridge" "Nucleoplasm, Cytosol" "HPA040910: AB_2677195, HPA048122: AB_2680272" "unprognostic (6.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.10e-2)" "unprognostic (2.25e-1)" "unprognostic (8.23e-3)" "unprognostic (2.80e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (8.57e-2)" "unprognostic (9.37e-2)" "prognostic favorable (1.58e-4)" "unprognostic (2.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.61e-2)" "unprognostic (6.29e-5)" 4.8 0.7 1.3 1.5 1.4 0.1 3.6 1.2 1.1 6.0 2.3 3.7 0.6 4.7 1.7 2.2 4.7 2.7 3.1 1.3 1.4 2.6 0.7 2.1 1.9 1.6 1.5 7.8 1.7 3.1 1.1 1.3 1.2 3.2 0.6 0.3 2.8 2.0 1.1 3.8 2.0 2.3 1.4 1.0 2.1 1.6 1.5 1.0 3.8 1.9 1.7 4.1 4.4 1.3 0.0 2.7 0.0 6.6 8.4 9.3 0.0 4.1 9.7 3.6 6.0 0.0 0.0 5.2 0.0 3.3 2.0 2.8 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 5.9 4.6 4.6 10.6 0.0 3.9 0.0 0.0 0.2 5.3 0.0 0.0 0.0 3.9 0.0 0.0 8.6 8.2 0.0 0.4 0.0 0.4 0.6 0.0 0.0 0.0 1.6 0.0 0.5 6.7 0.0 0.0 2.4 0.0 4.1 4.7 1.2 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 1.4 1.2 1.1 1.3 1.4 1.6 1.5 1.2 1.4 1.5 1.3 0.6 0.0 0.5 17.6 0.8 2.2 4.9 2.3 12.0 0.0 0.9 2.2 1.0 1.5 1.3 0.0 0.0 8.3 1.7 0.0 0.0 1.9 2.2 0.7 5.6 1.2 0.0 0.4 0.3 0.5 0.3 8.9 0.5 1.7 2.5 4.7 1.4 0.1 0.5 0.0 0.3 0.0 0.0 0.3 1.2 0.9 11.5 0.8 0.0 6.5 0.0 1.9 1.0 1.0 0.3 0.6 0.0 7.9 1.7 2.8 0.0 0.9 1.0 0.1 0.0 14.7 3.2 1.8 2.1 4.4 0.9 1.4 2.8 3.4 0.0 1.4 EXOC1 "BM-102, FLJ10893, SEC3, SEC3L1, Sec3p" ENSG00000090989 "Exocyst complex component 1" Q9NV70 4 55853648-55905086 "Predicted intracellular proteins, Transporters" "Antiviral defense, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037706, HPA044873" Uncertain Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Microtubules, Cytosol" "HPA037706: AB_10670525, HPA044873: AB_2679125" "unprognostic (7.10e-3)" "unprognostic (4.48e-2)" "unprognostic (8.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.81e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (2.84e-3)" "unprognostic (4.65e-2)" "unprognostic (2.04e-2)" "unprognostic (4.03e-3)" "unprognostic (1.55e-1)" "unprognostic (1.94e-1)" "unprognostic (3.11e-1)" "unprognostic (2.93e-2)" "unprognostic (6.24e-2)" "prognostic favorable (5.50e-5)" 19.7 16.5 18.1 17.3 20.4 12.7 20.0 20.4 20.0 18.9 18.7 18.0 16.8 16.6 20.4 29.3 16.5 15.5 16.5 18.3 20.0 15.9 10.2 17.4 18.3 21.1 19.2 15.1 12.9 20.5 14.5 20.8 20.3 14.3 19.1 18.5 17.4 12.8 13.6 28.1 16.2 15.7 20.4 20.8 15.6 16.9 20.1 13.9 16.3 13.5 20.0 16.2 20.1 25.1 21.8 12.4 21.9 25.3 36.9 45.9 14.6 30.2 30.1 24.1 25.1 8.6 37.1 20.9 20.6 32.6 29.1 25.4 18.0 23.9 34.5 11.1 12.4 19.4 14.8 10.1 34.7 21.3 26.4 37.4 32.1 25.1 27.6 31.2 39.9 16.0 28.3 20.1 53.0 13.8 15.6 21.5 13.9 31.2 23.4 18.0 16.4 17.1 26.9 23.6 16.2 28.7 18.0 29.2 25.5 18.5 18.6 22.6 48.5 29.7 24.2 25.8 26.3 23.9 12.7 18.4 38.6 23.4 28.8 21.3 14.6 13.1 6.5 19.0 8.8 8.4 9.2 9.5 14.3 8.3 8.3 6.0 19.5 12.5 23.6 6.4 11.6 7.9 18.1 20.4 20.4 20.0 18.3 20.0 21.1 19.2 20.3 20.4 20.1 25.1 44.7 41.7 38.0 77.4 24.5 34.8 14.8 34.0 22.2 48.8 26.4 21.2 29.1 17.2 35.6 22.0 31.3 60.8 21.4 38.3 19.6 23.6 45.3 41.0 47.5 39.0 22.2 19.6 72.6 20.0 31.6 28.9 22.4 37.2 36.7 35.5 40.0 12.3 40.9 28.6 86.5 28.8 24.4 37.7 47.4 16.7 21.5 37.8 40.9 56.2 38.7 40.3 22.6 73.4 138.0 36.2 32.4 23.7 19.0 17.4 37.6 21.9 44.7 32.5 32.9 25.9 27.9 47.6 31.6 42.5 39.9 51.2 27.8 44.6 28.7 26.8 EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 19.0;thyroid gland: 17.9" "Group enriched" "Detected in some" 4 "Adipocytes: 15.3;Endothelial cells: 17.7;Hepatic stellate cells: 51.4;Theca cells: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 19.1;K-562: 16.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" 4.3 8.3 0.3 2.1 0.6 1.6 2.9 0.5 0.4 4.0 1.6 2.7 2.4 4.9 0.4 1.9 2.8 2.3 2.3 0.4 0.3 19.0 2.7 2.7 1.1 0.7 0.5 0.9 2.7 3.3 5.0 0.4 0.5 5.2 0.7 0.1 1.8 2.2 0.9 2.1 3.2 1.9 0.3 8.3 2.9 3.3 0.4 0.4 17.9 0.3 0.5 3.2 2.4 0.7 0.1 0.3 2.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 19.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 16.6 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 1.0 0.1 0.3 0.6 0.8 1.5 0.2 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.4 0.4 0.3 0.7 0.5 0.5 0.3 0.4 0.7 15.3 0.0 1.3 0.7 0.7 0.4 0.3 0.0 0.0 0.7 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 17.7 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.2 0.0 0.4 51.4 0.3 0.0 0.0 1.1 0.6 0.0 1.6 0.0 0.0 1.8 2.8 0.0 0.0 0.1 0.2 2.1 0.5 0.7 0.0 0.0 1.9 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.6 0.4 6.2 0.2 0.9 0.0 0.1 21.2 0.0 0.3 EXOC4 "KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p" ENSG00000131558 "Exocyst complex component 4" Q96A65 7 133253073-134066589 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 238.6;Excitatory neurons: 334.2;Inhibitory neurons: 306.8;Microglial cells: 341.0;Oligodendrocyte precursor cells: 395.6;Oligodendrocytes: 345.9;Rod photoreceptor cells: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031443, HPA031444" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 10000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA031443: AB_10602496, HPA031444: AB_2673886" "unprognostic (1.70e-1)" "unprognostic (1.62e-2)" "unprognostic (2.05e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (8.63e-2)" "unprognostic (2.33e-1)" "unprognostic (4.40e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (9.78e-3)" "prognostic favorable (6.85e-5)" "unprognostic (5.91e-2)" "unprognostic (2.18e-1)" "unprognostic (3.37e-1)" "unprognostic (3.35e-2)" 20.7 21.1 18.7 13.8 20.2 13.8 21.4 19.3 20.3 22.6 24.3 19.7 13.1 21.5 13.6 24.4 27.3 17.8 15.3 20.9 19.4 17.7 17.8 17.7 16.4 18.4 20.3 30.6 27.3 27.3 16.9 19.6 19.9 18.3 21.5 53.1 16.3 20.5 68.4 25.4 13.5 23.9 18.8 21.0 17.3 18.7 19.1 28.1 26.4 38.5 20.3 21.1 18.6 20.8 40.1 32.2 43.3 43.3 49.7 51.6 15.0 28.6 47.2 25.4 33.2 18.8 54.7 29.8 20.1 54.1 36.9 24.7 23.7 38.8 41.8 45.6 28.2 24.0 31.5 19.9 54.7 32.0 25.1 50.4 47.6 36.3 66.5 55.7 43.5 38.6 35.1 28.8 47.7 26.1 58.5 35.2 32.8 47.5 29.8 25.7 38.7 54.2 40.7 35.2 33.9 53.2 43.0 39.1 46.3 48.9 25.8 29.3 47.9 28.1 14.6 30.0 31.5 45.0 29.4 28.1 82.9 36.4 43.8 10.3 12.0 7.2 11.2 12.9 10.0 8.3 11.6 11.9 16.3 8.1 9.4 9.6 4.0 19.6 11.4 7.2 12.9 11.2 18.7 20.2 19.3 20.3 20.9 19.4 18.4 20.3 19.9 18.8 19.1 20.8 22.9 22.4 22.3 238.6 27.3 18.9 16.3 16.6 25.6 39.9 16.8 15.4 30.9 11.5 18.0 14.7 93.8 17.5 26.7 21.5 3.9 15.0 29.6 27.0 21.2 23.0 17.4 18.7 334.2 18.2 16.6 21.2 34.1 21.0 8.2 32.4 23.2 15.9 18.1 50.5 306.8 21.0 26.4 27.3 14.5 27.6 17.4 20.4 14.2 341.0 23.9 20.4 23.7 395.6 345.9 15.4 17.4 18.8 27.7 13.2 16.3 16.9 29.8 231.5 13.1 26.0 15.3 20.5 13.1 28.2 17.0 11.2 26.2 26.4 21.9 20.1 EXOC6B "KIAA0919, SEC15B, SEC15L2" ENSG00000144036 "Exocyst complex component 6B" Q9Y2D4 2 72175984-72826041 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.7" "Cell type enhanced" "Detected in many" "Astrocytes: 210.3;Excitatory neurons: 351.1;Inhibitory neurons: 393.6;Microglial cells: 286.7;Oligodendrocyte precursor cells: 288.5;Oligodendrocytes: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034546, HPA063991" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034546: AB_2674218, HPA063991: AB_2685168" "unprognostic (5.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.18e-3)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "unprognostic (1.06e-2)" "unprognostic (9.34e-2)" "unprognostic (1.32e-1)" "unprognostic (2.16e-3)" "unprognostic (3.38e-2)" "unprognostic (2.61e-1)" "unprognostic (4.35e-3)" "unprognostic (4.38e-3)" "unprognostic (1.55e-1)" "unprognostic (1.18e-1)" "unprognostic (5.29e-2)" 11.3 13.4 22.3 4.2 32.7 1.2 8.6 18.8 23.9 12.6 3.2 8.6 7.3 10.1 6.0 15.1 7.8 6.5 50.7 20.7 25.7 7.2 3.8 7.2 3.1 23.9 25.7 15.0 5.0 13.2 6.1 13.0 23.3 8.0 5.7 14.1 7.7 8.9 11.1 26.5 9.1 10.0 16.4 5.2 6.9 6.9 22.2 4.4 10.2 11.5 6.4 9.7 13.0 40.9 21.7 16.3 14.7 17.8 41.2 16.9 25.3 15.6 21.9 13.2 8.6 22.3 3.3 5.6 9.5 26.2 19.6 35.4 12.4 25.7 18.9 4.2 10.1 16.7 11.0 12.8 22.2 2.4 5.5 14.6 36.6 14.9 23.1 20.6 21.8 8.7 1.8 0.0 17.6 7.5 6.4 2.9 15.3 14.9 9.0 3.4 26.4 2.3 12.7 50.1 7.3 6.3 26.7 8.2 10.9 16.1 5.7 2.3 24.3 15.2 12.8 13.1 9.6 5.5 5.9 0.0 17.7 1.2 12.4 1.3 0.5 0.0 0.7 0.4 0.5 0.7 0.5 0.4 0.4 0.7 0.6 0.9 0.0 0.5 0.6 0.1 0.8 0.4 22.3 32.7 18.8 23.9 20.7 25.7 23.9 25.7 23.3 16.4 22.2 40.9 17.8 0.0 4.1 210.3 4.1 26.1 10.2 9.8 14.8 17.4 5.2 5.2 87.1 12.8 5.1 9.2 25.0 15.1 5.0 10.2 5.9 9.3 62.9 5.6 14.5 14.1 3.0 2.1 351.1 11.5 13.2 12.4 30.5 9.2 8.2 11.6 11.4 5.6 4.6 16.8 393.6 6.0 4.1 12.0 7.1 8.2 8.4 5.0 5.4 286.7 2.0 9.9 1.0 288.5 863.3 11.0 8.6 7.5 3.7 8.1 28.2 5.5 8.4 11.1 0.0 13.5 14.7 12.0 4.9 13.1 37.4 24.6 4.7 5.5 4.5 10.7 EXOC7 "BLOM4, EXO70, Exo70p, KIAA1067, YJL085W" ENSG00000182473 "Exocyst complex component 7" Q9UPT5 17 76081016-76121576 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022840, HPA022842" Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "Vesicles, Plasma membrane" "HPA022840: AB_1848316, HPA022842: AB_1848317" "unprognostic (5.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" 40.4 31.4 36.0 32.7 37.0 53.2 31.2 31.4 36.7 39.3 34.1 40.1 32.5 40.1 33.1 52.3 52.3 35.4 47.2 36.8 35.5 31.9 30.2 35.9 32.7 35.4 34.3 49.6 41.1 61.2 41.0 35.3 36.5 48.1 27.9 24.7 50.6 43.1 43.0 37.0 34.7 43.5 31.9 32.4 30.3 24.9 36.4 43.5 43.0 41.4 32.3 44.3 30.1 34.8 65.6 79.4 71.9 58.5 66.6 47.0 74.5 58.9 77.6 103.9 74.7 67.5 43.0 33.7 42.0 103.0 65.6 52.7 43.9 57.1 69.0 29.3 59.1 55.8 64.0 72.3 46.4 62.9 55.7 66.1 44.3 80.5 39.2 73.5 116.9 59.8 38.1 33.7 65.6 59.8 102.1 27.8 37.8 49.5 83.4 54.0 123.3 34.6 59.7 133.6 38.9 91.4 66.5 48.6 44.6 68.8 79.7 51.0 77.5 111.3 66.3 74.1 65.8 46.0 18.2 31.2 66.4 28.0 59.0 55.1 41.1 66.1 35.5 57.4 24.4 26.7 26.9 30.4 28.9 26.9 27.7 23.9 46.2 36.4 79.7 12.3 32.0 44.9 36.0 37.0 31.4 36.7 36.8 35.5 35.4 34.3 36.5 31.9 36.4 34.8 31.0 19.2 35.0 36.6 37.7 19.8 40.1 40.8 31.3 87.6 30.2 28.8 7.5 28.6 41.4 40.5 143.9 51.5 37.5 47.6 33.2 38.3 22.4 35.1 25.8 27.1 48.9 48.6 26.2 37.1 29.0 31.6 27.0 34.4 41.1 65.0 30.7 27.0 37.7 67.3 31.1 43.8 54.9 29.6 21.3 52.2 37.3 26.9 24.9 15.0 36.8 52.1 56.7 44.2 35.0 44.6 41.4 38.4 15.7 41.5 62.8 35.3 43.7 108.8 46.0 27.8 49.5 32.1 16.6 20.3 19.9 71.1 35.8 56.6 29.8 44.8 EXOSC10 "p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p" ENSG00000171824 "Exosome component 10" Q01780 1 11066618-11099869 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028470, HPA028484, CAB037141" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "CAB037141: AB_532315, HPA028470: AB_10599180, HPA028484: AB_10611250" "unprognostic (1.23e-2)" "unprognostic (3.46e-2)" "unprognostic (1.85e-2)" "unprognostic (1.62e-1)" "unprognostic (6.88e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (2.49e-6)" "unprognostic (3.36e-1)" "unprognostic (4.66e-2)" "unprognostic (2.52e-1)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (7.68e-3)" "unprognostic (3.43e-1)" "unprognostic (9.03e-2)" "prognostic favorable (5.27e-4)" "unprognostic (1.33e-1)" 31.8 21.4 18.3 25.9 18.4 39.4 30.8 23.1 22.2 32.5 14.7 27.6 20.7 28.7 23.9 27.3 26.4 19.2 20.3 17.7 15.9 21.8 20.0 24.3 31.1 17.2 15.2 35.8 24.0 25.2 26.1 26.1 16.6 25.3 27.6 35.4 25.4 21.0 33.3 37.0 26.1 27.5 13.7 27.4 26.1 23.4 17.9 32.7 23.3 22.6 34.2 24.6 28.4 19.1 66.4 41.5 84.9 33.0 44.3 48.7 48.5 63.8 46.8 109.8 99.1 61.6 94.1 66.3 40.3 61.0 48.8 64.2 95.0 71.2 100.1 74.9 95.0 96.5 80.5 63.2 43.4 79.5 73.7 38.4 60.2 108.1 63.1 40.9 69.4 58.0 103.2 59.3 61.4 37.4 78.5 73.1 56.5 50.3 49.1 79.8 72.2 58.1 64.8 33.3 54.5 53.3 68.8 58.9 77.0 59.4 51.5 72.1 63.6 58.2 60.4 53.0 76.2 35.7 60.0 130.0 59.4 116.2 71.5 57.7 32.0 26.6 36.2 41.5 43.0 36.4 37.7 36.7 37.9 36.5 31.9 35.4 6.2 49.3 51.2 19.3 39.4 43.3 18.3 18.4 23.1 22.2 17.7 15.9 17.2 15.2 16.6 13.7 17.9 19.1 18.4 28.9 18.3 17.0 26.1 13.3 14.3 19.8 26.2 14.9 11.0 23.6 6.4 12.8 29.2 5.5 47.9 26.5 18.8 16.4 9.8 25.0 16.4 14.3 21.0 20.1 9.0 28.0 20.3 31.9 34.3 17.2 31.1 19.2 20.2 26.2 13.9 11.1 24.7 21.9 24.3 16.5 22.4 15.1 14.1 7.1 29.5 18.7 12.4 9.4 24.0 6.1 28.8 30.2 15.2 30.2 9.4 23.0 26.8 8.5 12.7 8.8 27.3 34.8 13.1 18.4 17.6 21.9 20.8 28.7 13.4 22.7 21.2 19.7 20.1 10.0 EXOSC4 "FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p" ENSG00000178896 "Exosome component 4" Q9NPD3 8 144078648-144080648 "Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.9" "Group enriched" "Detected in many" 4 "Early spermatids: 320.6;Late spermatids: 856.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 430.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024792, HPA065103" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Vesicles "HPA024792: AB_1848325, HPA065103: " "unprognostic (2.32e-1)" "unprognostic (1.55e-2)" "unprognostic (3.06e-1)" "unprognostic (3.53e-2)" "unprognostic (1.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.58e-3)" "unprognostic (1.26e-1)" "unprognostic (8.36e-2)" "prognostic favorable (2.23e-4)" "unprognostic (4.32e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "unprognostic (5.18e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (5.11e-2)" 19.3 31.2 15.1 11.4 16.5 14.9 16.9 16.0 23.4 13.1 16.1 18.8 15.4 17.0 5.0 27.5 16.1 7.2 23.7 15.6 15.0 23.6 35.0 16.0 12.1 16.8 14.9 12.3 18.8 10.3 17.6 9.2 15.5 18.8 5.7 3.5 26.6 12.5 21.2 22.1 15.2 6.1 15.4 23.8 24.0 94.9 15.8 10.1 13.9 8.2 6.6 17.4 15.2 15.9 51.8 104.8 18.1 44.2 15.6 11.7 51.8 39.9 15.2 28.9 28.9 73.4 33.4 28.9 54.6 15.5 21.0 40.4 33.8 40.5 8.3 42.5 117.8 42.7 77.9 83.3 25.9 31.4 48.6 16.9 40.9 33.2 26.2 11.4 14.8 32.0 68.8 19.8 23.8 177.8 51.4 62.0 47.6 51.2 430.6 21.7 30.2 74.8 27.7 48.3 57.6 75.4 46.6 59.7 95.4 9.3 68.1 49.0 15.2 29.9 66.3 73.6 68.1 52.4 67.8 37.5 43.1 50.8 47.7 61.5 78.3 34.1 37.4 76.6 38.7 59.7 29.3 37.4 75.0 60.2 37.7 36.2 22.9 45.6 43.0 97.4 36.1 49.5 15.1 16.5 16.0 23.4 15.6 15.0 16.8 14.9 15.5 15.4 15.8 15.9 16.3 9.6 21.3 2.9 17.8 94.4 45.2 58.6 45.5 10.0 40.7 41.4 22.3 24.3 31.9 27.6 8.4 48.2 17.2 46.6 123.3 50.6 320.6 23.8 28.3 25.5 25.9 24.6 3.2 46.3 44.2 24.7 25.0 18.8 14.0 21.0 19.2 54.9 44.7 6.7 3.3 35.6 48.8 29.8 40.7 856.7 18.6 29.9 35.6 0.0 45.7 23.5 14.4 3.0 3.6 61.7 52.4 21.1 32.5 55.5 41.0 102.5 31.7 8.2 13.1 14.7 43.5 97.0 34.7 48.1 87.9 48.2 12.8 37.8 47.1 48.7 EXOSC8 "bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p" ENSG00000120699 "Exosome component 8" Q96B26 13 36998816-37009614 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034240, HPA039702, HPA043942, HPA075230" Uncertain Supported "Nucleoli fibrillar center,Mitotic chromosome,Vesicles" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitotic chromosome, Vesicles" "CAB034240: AB_2101977, HPA039702: AB_2676634, HPA043942: AB_2678742, HPA075230: " "unprognostic (8.67e-2)" "unprognostic (9.39e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (2.58e-2)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (4.01e-2)" "unprognostic (3.24e-3)" "unprognostic (2.45e-2)" "unprognostic (2.35e-2)" "unprognostic (7.32e-3)" "prognostic unfavorable (8.39e-7)" "unprognostic (9.58e-3)" "unprognostic (7.42e-2)" "unprognostic (1.10e-1)" "unprognostic (4.51e-1)" 15.0 14.2 16.6 19.1 17.6 27.5 18.8 17.9 24.3 16.8 16.6 17.0 12.6 14.2 14.4 18.2 16.8 8.4 19.4 16.9 17.8 17.9 19.8 13.5 21.2 17.5 17.1 16.4 13.9 11.6 10.8 15.6 18.1 14.2 19.0 15.3 11.3 13.2 24.2 16.6 14.0 16.6 17.3 17.5 15.3 27.8 17.0 31.5 12.3 24.8 25.1 16.2 14.7 19.7 47.5 33.5 97.7 66.4 28.4 30.1 73.8 68.9 48.8 93.2 74.2 72.7 93.6 65.1 29.8 38.2 91.4 64.7 92.7 67.1 111.5 96.3 73.9 174.8 34.2 87.4 37.0 148.3 58.9 17.4 51.3 62.6 100.2 24.1 72.8 93.6 86.6 41.3 66.4 59.1 78.6 116.6 101.4 113.2 44.0 48.5 98.6 53.5 51.1 30.8 23.8 46.1 38.1 44.5 65.3 51.1 35.4 117.6 37.2 35.5 49.1 42.9 95.5 23.3 29.4 135.7 56.0 104.1 66.8 28.9 29.8 23.5 42.8 39.6 44.8 66.0 54.1 50.5 33.9 57.2 67.1 62.7 6.0 46.2 41.7 54.8 54.6 52.4 16.6 17.6 17.9 24.3 16.9 17.8 17.5 17.1 18.1 17.3 17.0 19.7 43.5 32.1 38.9 15.7 40.1 36.1 51.6 109.6 25.0 20.8 25.0 50.0 50.2 18.6 69.5 11.0 8.4 86.8 46.8 13.1 56.7 58.1 115.7 21.5 31.4 39.4 13.2 57.9 7.0 52.1 92.3 41.8 19.4 20.6 103.6 46.2 18.5 17.4 46.8 28.6 8.6 19.1 79.3 13.6 34.2 54.6 40.7 26.0 26.6 10.3 32.6 27.1 35.0 17.1 22.0 36.1 16.4 36.5 38.8 29.0 18.0 26.6 53.4 32.0 26.3 38.8 52.1 163.3 85.9 29.0 36.2 67.0 38.7 42.7 30.2 37.7 FAAP20 "C1orf86, FLJ31031" ENSG00000162585 "FA core complex associated protein 20" Q6NZ36 1 2184461-2212720 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 337.5;Proximal tubular cells: 290.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038829 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Cell Junctions" "HPA038829: AB_10673476" "unprognostic (1.36e-2)" "unprognostic (2.86e-2)" "unprognostic (2.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.64e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (2.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.88e-4)" "unprognostic (1.59e-1)" "unprognostic (1.96e-3)" "unprognostic (1.36e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (8.55e-2)" 39.3 57.5 18.1 3.2 18.9 5.6 41.2 20.8 28.0 52.5 20.5 48.5 4.6 50.0 1.3 38.8 37.8 1.5 50.0 14.5 19.6 64.8 52.1 37.9 3.6 24.6 18.9 45.3 38.7 5.1 75.5 3.2 19.6 61.1 1.8 3.7 30.7 7.1 26.4 42.7 31.8 1.8 20.2 45.0 47.3 54.8 26.9 2.9 52.9 4.0 3.1 43.7 40.7 18.9 27.7 4.4 5.8 7.3 3.6 4.7 34.8 30.4 11.0 9.6 12.9 6.7 18.0 31.7 43.7 4.8 9.0 13.5 4.2 4.6 4.9 68.3 61.0 26.5 6.8 14.4 13.5 18.7 24.8 8.1 9.8 5.8 6.3 5.9 11.9 24.6 37.1 7.6 6.7 11.6 27.0 57.6 20.8 5.4 55.6 36.0 18.1 30.7 4.6 4.5 47.4 63.5 19.8 8.6 58.5 5.3 8.5 7.5 25.6 15.1 35.8 18.7 17.4 68.9 39.9 48.2 28.0 11.4 6.4 9.8 16.4 63.4 18.4 16.9 18.1 28.3 16.5 19.8 17.0 25.7 22.2 18.6 20.6 10.8 15.6 42.4 16.2 10.6 18.1 18.9 20.8 28.0 14.5 19.6 24.6 18.9 19.6 20.2 26.9 18.9 71.7 6.4 11.9 0.0 82.3 0.0 97.7 0.0 79.6 29.1 120.9 138.2 22.1 62.9 6.8 97.5 4.2 119.7 83.6 14.5 170.2 128.5 102.7 44.3 77.2 62.1 43.7 36.8 0.0 110.8 144.1 65.3 64.7 49.9 7.6 74.8 84.6 94.5 134.0 15.2 0.0 56.0 0.0 110.8 0.0 337.5 86.0 82.3 0.0 0.0 178.9 84.7 91.6 0.0 0.0 141.1 40.8 82.8 60.9 152.8 56.2 290.1 8.0 29.5 65.7 63.3 68.8 101.5 38.3 88.4 0.0 89.8 62.4 102.5 42.2 113.2 FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "intestine: 550.0" "Cell type enriched" "Detected in some" 10 "Proximal enterocytes: 5965.8" "Group enriched" "Detected in some" 9 "colorectal cancer: 3.2;pancreatic cancer: 1.6;stomach cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RPMI-8226: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 61000 "Cluster 1: Neutrophils - Mixed function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: AB_10601317" "unprognostic (3.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (4.58e-1)" "unprognostic (1.51e-2)" "unprognostic (2.61e-2)" "unprognostic (1.69e-4)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" 0.2 0.1 0.1 3.1 0.1 0.9 0.0 0.6 0.2 0.0 0.4 28.2 291.0 0.3 0.1 0.1 0.2 0.1 0.6 0.2 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.2 0.3 0.0 0.0 0.1 0.4 550.0 1.9 0.0 0.1 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.3 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.6 0.4 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.2 4.2 0.4 0.1 0.3 0.3 0.0 0.1 0.1 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.8 0.0 0.0 0.0 242.0 0.0 0.0 0.0 1.4 0.1 0.1 1.2 0.0 0.0 0.2 0.1 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 570.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 383.1 0.0 0.0 0.0 5965.8 17.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 222.5 0.0 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FABP7 "B-FABP, BLBP" ENSG00000164434 "Fatty acid binding protein 7" O15540 6 122779716-122784074 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 366.1;choroid plexus: 164.8;retina: 175.3;tongue: 199.3" "Cell type enriched" "Detected in some" 6 "Muller glia cells: 1407.3" "Group enriched" "Detected in many" 6 "glioma: 139.3;renal cancer: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 105.5;U-251 MG: 28.8;WM-115: 63.7" "Region enriched" "Detected in all" 5 "olfactory bulb: 1195.2" "Low region specificity" "Detected in all" "CAB025488, HPA028825, CAB058697" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Golgi apparatus, Cytosol" "CAB025488: , CAB058697: AB_2665600, HPA028825: AB_10602130" "prognostic favorable (2.49e-4)" "unprognostic (1.56e-2)" "unprognostic (2.53e-3)" "unprognostic (5.80e-2)" "unprognostic (2.29e-1)" "unprognostic (1.14e-1)" "unprognostic (7.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (1.65e-6)" "unprognostic (9.83e-2)" "unprognostic (1.30e-2)" "unprognostic (2.50e-1)" "unprognostic (8.66e-2)" 1.9 0.4 184.8 0.1 210.5 0.3 38.0 228.1 366.1 1.2 164.8 0.7 0.1 0.1 0.2 0.8 0.1 0.1 0.3 198.7 176.2 0.8 0.3 0.0 0.1 188.0 175.5 0.1 0.1 0.0 8.0 0.4 171.2 0.3 0.1 175.3 8.8 3.9 8.8 41.8 0.1 0.0 170.8 0.0 0.4 0.2 174.0 1.8 0.0 199.3 0.1 0.2 0.4 182.9 0.0 0.1 105.5 0.0 0.0 0.0 3.8 0.0 0.9 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.1 0.2 0.1 0.2 0.0 0.1 28.8 0.0 0.0 0.0 1.2 0.1 63.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 184.8 210.5 228.1 366.1 198.7 176.2 188.0 175.5 171.2 170.8 174.0 182.9 0.1 0.0 0.0 14.0 0.0 12.2 0.3 0.0 0.0 11.6 44.5 38.9 1.3 0.0 0.0 0.0 12.5 4.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 2.9 0.0 228.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 5.0 1.1 0.0 0.0 0.0 1.4 0.0 0.0 0.1 30.2 0.0 0.0 1407.3 0.0 41.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 48.0 0.0 0.5 0.3 0.0 0.3 0.0 18.9 7.1 0.3 0.0 0.0 0.0 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 204.7;BJ hTERT+: 244.1;fHDF/TERT166: 273.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 96000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: AB_2685931, HPA069104: AB_2686087, HPA069701: AB_2686175" "unprognostic (2.13e-3)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (4.66e-2)" "unprognostic (9.40e-3)" "unprognostic (6.77e-2)" "unprognostic (2.54e-1)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.63e-6)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (3.44e-3)" 28.4 48.1 7.9 23.6 11.8 2.0 20.2 7.8 9.2 48.4 23.7 34.6 22.9 29.2 17.8 35.1 19.5 36.4 23.7 9.9 11.4 11.8 54.2 21.2 8.9 13.7 12.5 41.5 25.6 22.4 18.5 35.6 11.2 35.5 33.7 3.1 61.2 27.8 16.6 15.6 24.4 61.7 9.0 8.8 34.4 12.5 12.1 4.3 17.6 22.7 19.5 35.6 26.4 13.4 43.5 30.7 18.5 21.9 197.4 204.7 6.1 167.9 244.1 69.7 105.8 8.1 33.0 0.0 23.0 273.8 118.8 11.9 0.1 53.7 80.1 0.2 4.6 3.1 30.3 40.6 70.6 0.1 5.8 122.1 17.0 101.2 23.3 157.2 101.4 0.1 3.4 0.2 102.9 11.0 0.1 2.3 3.8 18.3 15.6 0.8 90.9 3.2 23.4 8.7 0.7 9.4 33.8 0.7 33.8 42.8 20.8 3.8 156.3 75.4 34.8 95.3 39.5 0.7 0.2 0.3 123.3 3.3 63.0 0.6 3.2 0.0 0.1 3.6 0.0 0.4 0.1 0.1 2.6 0.1 0.1 0.1 2.4 0.0 1.4 0.3 0.0 0.9 7.9 11.8 7.8 9.2 9.9 11.4 13.7 12.5 11.2 9.0 12.1 13.4 28.1 16.0 13.2 5.9 2.2 12.2 47.4 43.7 15.4 0.3 29.9 21.2 17.2 14.3 56.0 7.3 0.0 2.2 0.2 46.8 9.8 45.6 1.0 17.5 88.6 35.2 15.7 3.6 1.0 61.0 47.0 94.9 35.7 39.1 1.3 30.4 31.1 68.3 16.1 0.0 1.8 78.7 83.4 7.2 15.0 6.3 110.9 8.7 21.4 17.8 6.4 12.2 0.0 14.6 31.0 47.6 41.6 116.2 8.5 92.6 39.0 11.7 47.8 1.2 19.7 49.4 44.3 1.2 5.5 23.6 10.2 3.4 3.1 94.1 32.0 82.7 FAM131C "C1orf117, FLJ36766" ENSG00000185519 "Family with sequence similarity 131 member C" Q96AQ9 1 16057769-16073651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.3;kidney: 14.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 9.2;Distal tubular cells: 19.6;Horizontal cells: 38.7;Muller glia cells: 31.8" "Cancer enhanced" "Detected in many" "renal cancer: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.8;HEK 293: 5.3;PC-3: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031046 Uncertain Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nucleoli, Intermediate filaments, Cytosol" "HPA031046: AB_2673711" "unprognostic (4.69e-3)" "unprognostic (4.98e-2)" "unprognostic (7.26e-2)" "unprognostic (2.46e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (1.63e-2)" "unprognostic (4.67e-4)" "unprognostic (2.82e-1)" "unprognostic (1.93e-2)" "unprognostic (1.75e-1)" "unprognostic (1.68e-1)" "prognostic favorable (9.33e-6)" "unprognostic (1.93e-1)" "unprognostic (2.29e-1)" "unprognostic (2.82e-2)" "unprognostic (1.44e-1)" 0.3 6.9 10.3 0.0 13.8 0.0 0.2 40.3 12.3 1.1 3.3 0.3 0.0 0.5 0.2 1.5 0.5 0.3 5.6 8.5 15.3 14.9 0.5 0.0 0.0 15.9 14.4 0.4 3.5 3.3 9.4 0.0 18.4 0.2 0.0 3.1 1.9 0.3 0.1 2.7 0.9 0.1 13.5 0.1 1.0 0.7 13.5 0.1 1.2 0.2 0.3 0.2 0.9 20.8 3.3 7.8 0.2 0.4 0.0 0.0 0.0 0.7 0.6 0.8 1.9 0.2 1.7 0.0 0.3 0.4 1.9 0.9 1.0 0.2 0.2 0.0 5.3 0.0 1.6 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.6 2.6 0.5 0.2 0.0 0.0 0.1 1.6 0.0 0.0 0.3 1.6 6.0 0.0 0.0 3.5 0.6 0.0 1.1 2.3 0.2 0.9 0.2 0.0 0.2 0.0 1.2 0.1 2.7 0.0 0.0 1.3 0.1 0.0 2.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 13.8 40.3 12.3 8.5 15.3 15.9 14.4 18.4 13.5 13.5 20.8 0.1 0.0 0.0 4.9 0.0 0.3 0.4 0.3 0.0 6.5 0.6 1.0 2.1 1.5 0.3 9.2 4.2 0.1 0.0 0.0 19.6 2.6 1.3 0.3 0.1 0.3 3.5 0.0 0.7 0.4 0.0 0.3 0.0 0.2 0.0 0.3 0.7 0.4 0.0 38.7 8.9 0.0 6.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 2.6 31.8 0.0 0.0 7.1 0.3 0.0 0.0 0.4 0.5 0.0 0.8 0.2 2.4 0.0 2.3 0.4 0.7 3.5 0.2 1.1 0.0 0.1 0.0 0.1 0.5 FAM13A "ARHGAP48, FAM13A1, KIAA0914" ENSG00000138640 "Family with sequence similarity 13 member A" O94988 4 88725955-89111398 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.0;Oligodendrocyte precursor cells: 157.8;Syncytiotrophoblasts: 279.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038108, HPA038109" Uncertain Approved "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Cytosol" Nucleoli "HPA038108: AB_2675837, HPA038109: AB_10672619" "unprognostic (1.14e-1)" "unprognostic (1.53e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.46e-3)" "unprognostic (6.36e-2)" "unprognostic (4.71e-1)" "unprognostic (3.49e-3)" "unprognostic (1.90e-2)" "unprognostic (7.44e-2)" "prognostic favorable (4.28e-4)" 49.2 12.8 8.5 9.9 9.0 12.7 31.8 14.2 11.8 17.6 13.2 18.3 50.5 12.5 7.5 7.6 23.5 16.3 9.9 9.7 7.3 21.9 39.1 11.8 6.3 8.6 8.4 27.8 38.6 49.2 8.4 35.1 9.5 10.6 14.8 15.9 23.4 10.5 9.7 20.4 29.0 13.3 8.3 5.4 16.3 13.9 9.0 5.6 32.8 21.9 4.8 16.9 10.4 8.8 4.5 6.7 9.8 12.8 55.5 22.7 16.0 10.2 12.4 4.0 3.6 5.6 10.3 0.1 4.0 7.4 6.3 2.7 14.5 7.4 8.9 0.6 10.0 7.5 8.9 0.7 16.3 6.3 1.0 21.9 5.9 10.1 3.6 17.5 6.9 2.5 19.7 0.7 8.7 0.2 0.7 2.8 12.1 0.8 6.9 10.2 16.6 4.0 7.4 21.8 24.6 6.5 2.5 7.9 9.9 9.6 5.5 0.2 2.5 11.2 6.2 5.5 5.9 3.4 2.1 0.1 16.6 0.6 5.9 0.0 4.1 0.0 1.0 2.0 0.7 0.0 2.7 0.3 3.5 0.0 2.9 0.7 0.9 0.4 0.6 1.2 1.5 1.6 8.5 9.0 14.2 11.8 9.7 7.3 8.6 8.4 9.5 8.3 9.0 8.8 42.6 12.8 34.9 95.3 4.3 10.1 22.3 20.4 28.5 16.3 29.7 20.6 25.9 38.6 39.3 11.0 35.5 72.9 12.9 50.4 29.4 10.7 3.4 82.0 33.6 14.1 4.9 31.3 178.0 16.9 35.3 42.1 33.1 98.2 1.3 70.2 12.8 143.0 20.7 0.0 46.5 54.1 26.4 29.6 11.9 5.1 45.1 21.7 19.6 104.9 16.9 22.6 5.2 157.8 17.4 20.7 73.4 33.4 10.3 13.6 37.5 50.4 74.6 11.3 0.0 24.7 31.9 5.3 10.2 14.4 7.7 279.5 9.7 41.2 22.3 19.5 FAM161B "C14orf44, FLJ31697" ENSG00000156050 "FAM161 centrosomal protein B" Q96MY7 14 73931501-73950414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 62.9;Late spermatids: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019125 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA019125: AB_1845570" "unprognostic (1.50e-1)" "unprognostic (9.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.99e-1)" "unprognostic (9.51e-2)" "unprognostic (1.79e-2)" "unprognostic (1.76e-3)" "unprognostic (5.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (7.83e-2)" "unprognostic (1.53e-1)" "prognostic favorable (6.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (1.60e-1)" 2.7 8.7 6.6 1.7 6.6 1.2 4.8 5.8 8.2 5.3 3.4 3.9 3.3 5.2 4.3 4.1 5.5 2.7 5.4 6.4 5.9 7.2 5.1 2.8 1.8 6.8 5.7 12.8 2.2 4.3 7.6 2.4 7.1 6.0 2.7 10.1 2.8 5.2 7.9 2.1 3.3 3.4 5.5 3.1 3.3 18.8 6.1 1.9 4.2 4.8 1.8 5.5 3.8 6.6 2.1 1.6 2.2 3.4 4.7 3.5 2.0 3.6 2.8 6.0 5.8 1.5 2.6 3.3 2.3 4.2 2.5 3.9 0.9 1.7 4.1 9.2 1.8 1.6 1.6 1.7 4.0 1.1 2.3 2.6 3.4 6.1 2.2 4.4 2.7 3.4 1.0 1.6 4.3 3.3 3.1 4.2 0.5 1.4 3.5 2.1 2.9 1.3 3.1 3.1 2.7 2.5 5.1 2.3 3.1 1.6 8.1 1.5 2.9 12.4 5.6 3.1 2.2 3.3 2.2 2.1 6.3 1.9 2.2 3.2 1.3 1.9 1.1 0.3 1.3 0.7 1.2 1.7 0.2 0.9 0.6 0.4 0.4 1.3 0.4 0.3 0.7 0.9 6.6 6.6 5.8 8.2 6.4 5.9 6.8 5.7 7.1 5.5 6.1 6.6 3.5 3.2 4.8 4.9 3.0 0.6 2.1 1.0 3.4 8.9 3.7 3.8 3.4 0.0 3.2 1.8 4.2 1.5 1.9 3.5 0.0 1.0 62.9 5.9 3.9 2.2 0.0 1.7 7.3 1.6 1.1 4.6 7.1 4.5 0.0 5.0 2.5 0.7 2.9 3.3 8.6 4.1 2.0 1.2 0.7 142.7 3.4 1.4 1.8 2.8 2.2 8.0 6.2 5.5 2.9 1.2 0.8 9.4 1.4 0.8 4.3 4.2 9.4 16.7 6.6 5.2 4.2 11.0 6.1 0.6 0.9 2.2 3.3 9.6 1.4 0.9 FAM163B C9orf166 ENSG00000196990 "Family with sequence similarity 163 member B" P0C2L3 9 133577081-133609389 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.1" "Group enriched" "Detected in some" 6 "Excitatory neurons: 24.8;Inhibitory neurons: 17.8;Late spermatids: 17.3" "Cancer enriched" "Detected in some" 6 "glioma: 3.2" "Group enriched" "Detected in many" 6 "amygdala: 26.5;basal ganglia: 44.4;cerebral cortex: 60.1;hippocampal formation: 38.2;white matter: 32.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "SH-SY5Y: 50.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067336 Enhanced Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies, Plasma membrane, Cytosol" "HPA067336: AB_2685825" "unprognostic (2.94e-2)" "unprognostic (6.87e-3)" "unprognostic (2.65e-2)" "unprognostic (2.70e-1)" "unprognostic (1.23e-2)" "unprognostic (9.05e-2)" "unprognostic (1.02e-2)" "unprognostic (3.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (5.75e-4)" "unprognostic (1.07e-1)" "unprognostic (9.54e-2)" "unprognostic (1.65e-1)" "unprognostic (4.73e-4)" 0.1 10.0 26.5 0.0 44.4 0.0 0.0 0.0 60.1 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.1 0.4 5.2 38.2 0.0 0.8 8.7 0.3 1.7 0.0 0.0 0.4 0.1 0.0 0.5 0.8 7.3 0.2 0.5 0.2 0.3 0.8 0.0 0.0 0.0 0.0 6.0 0.2 0.4 2.4 0.0 0.2 0.2 0.0 0.0 1.1 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.7 0.2 0.1 0.0 0.0 2.4 50.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 44.4 0.0 60.1 38.2 0.0 0.0 0.0 7.3 6.0 0.0 32.5 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 2.8 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM184A "C6orf60, FLJ13942" ENSG00000111879 "Family with sequence similarity 184 member A" Q8NB25 6 118959763-119149387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.3;choroid plexus: 30.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.0;Astrocytes: 261.2;Oligodendrocyte precursor cells: 88.4;Syncytiotrophoblasts: 266.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.8;HEK 293: 11.1;Hep G2: 7.9;JURKAT: 11.6;K-562: 10.4;SCLC-21H: 8.5;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034571, HPA034572, HPA041955" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA034571: AB_10602498, HPA034572: AB_2674228, HPA041955: AB_2677768" "unprognostic (1.21e-1)" "unprognostic (4.11e-3)" "unprognostic (6.95e-2)" "unprognostic (3.40e-3)" "unprognostic (6.80e-2)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-4)" "unprognostic (2.59e-1)" "unprognostic (3.19e-1)" "unprognostic (5.16e-4)" "unprognostic (8.38e-3)" "unprognostic (4.02e-2)" "unprognostic (9.11e-3)" "unprognostic (8.16e-3)" "unprognostic (5.70e-2)" "unprognostic (2.32e-1)" 3.1 1.6 33.3 1.3 36.3 0.2 4.7 37.3 43.3 3.6 30.5 3.5 3.0 2.5 3.0 1.4 3.2 1.8 2.5 34.3 33.0 6.7 6.3 9.9 3.5 31.9 32.4 4.5 3.2 4.8 11.0 23.0 32.4 3.9 0.9 16.3 3.3 2.8 0.9 1.7 1.6 1.6 29.1 0.6 1.7 16.9 32.6 0.6 7.0 2.2 3.5 2.4 2.1 34.5 0.1 0.3 11.8 0.9 0.3 0.3 0.0 0.6 0.4 0.5 0.9 2.0 1.1 0.9 0.0 0.2 5.3 0.0 3.4 0.0 0.2 1.3 11.1 0.1 0.9 7.9 0.2 0.0 0.6 0.4 0.1 0.1 0.0 0.3 0.0 11.6 10.4 0.7 0.3 0.3 0.4 0.1 6.0 0.6 1.3 0.0 0.1 0.0 0.1 0.1 8.5 8.0 0.7 0.6 1.8 2.2 2.1 1.4 0.3 0.8 0.5 0.2 2.9 4.9 3.3 0.3 1.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 33.3 36.3 37.3 43.3 34.3 33.0 31.9 32.4 32.4 29.1 32.6 34.5 21.0 48.1 103.0 261.2 0.7 2.4 5.9 0.4 11.4 35.2 3.8 8.8 6.4 2.8 17.7 3.7 29.2 61.4 0.6 0.4 17.6 1.0 22.9 2.0 2.0 5.3 6.0 0.4 66.9 1.1 18.9 11.8 1.5 0.8 6.3 8.9 1.8 4.0 5.6 13.5 55.5 0.6 0.0 0.3 1.8 9.2 3.7 1.0 0.0 34.7 0.0 11.1 0.0 88.4 20.6 0.3 1.2 7.2 2.7 1.6 0.4 3.1 37.3 28.4 6.6 45.2 4.1 61.8 16.0 4.2 3.4 266.4 5.8 1.4 0.7 2.0 FAM186A LOC121006 ENSG00000185958 "Family with sequence similarity 186 member A" A6NE01 12 50326230-50396622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 14.2" "Cell type enriched" "Detected in some" 8 "Early spermatids: 521.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047128, HPA064735" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA047128: AB_10967726, HPA064735: " "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.43e-2)" "unprognostic (1.30e-2)" "unprognostic (6.96e-2)" "unprognostic (4.65e-5)" "unprognostic (1.93e-1)" "unprognostic (2.42e-5)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (7.51e-2)" "unprognostic (3.22e-3)" 0.1 0.3 0.2 0.2 0.4 0.5 0.1 0.6 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.2 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.2 0.3 0.0 0.9 0.0 0.1 0.3 0.1 0.7 0.2 0.0 1.1 0.3 0.2 0.0 0.0 0.3 0.1 14.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.6 0.3 0.1 0.1 0.0 0.0 0.2 0.4 0.6 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 521.1 0.1 0.2 0.1 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 64.7 0.6 0.1 0.0 2.8 0.0 0.6 0.0 1.5 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM199X CXorf39 ENSG00000123575 "Family with sequence similarity 199, X-linked" Q6PEV8 X 104166453-104195902 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003093 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA003093: AB_1078597" "unprognostic (2.03e-3)" "unprognostic (4.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.18e-2)" "unprognostic (1.89e-2)" "unprognostic (6.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (9.13e-2)" "unprognostic (6.07e-3)" "unprognostic (1.08e-2)" "unprognostic (4.73e-2)" "unprognostic (4.00e-2)" "unprognostic (2.39e-2)" 19.9 11.7 17.0 7.1 16.9 13.8 11.6 18.2 18.7 9.2 10.2 8.4 7.9 10.6 34.8 7.8 9.1 6.8 7.3 15.2 18.8 15.1 7.7 8.1 8.6 15.5 19.1 11.9 11.1 19.9 8.5 9.0 17.5 10.2 8.4 16.1 10.2 13.9 9.4 9.5 7.2 8.7 16.8 8.8 8.3 10.1 20.5 9.0 17.5 9.7 7.8 8.0 7.6 18.8 23.9 14.9 13.2 14.5 9.6 11.5 13.3 12.4 11.6 15.8 14.7 11.6 19.4 13.1 15.0 11.4 12.5 17.6 23.9 18.3 25.7 6.4 13.4 10.4 19.0 13.2 13.7 20.0 14.1 9.0 22.9 15.5 15.6 24.7 16.2 8.3 11.5 28.6 17.8 17.1 10.8 14.2 13.2 20.9 17.3 11.4 8.6 16.5 26.9 15.8 7.1 8.8 30.0 19.7 21.4 12.9 9.8 9.8 20.1 17.6 6.4 13.8 13.5 13.6 12.1 14.4 19.8 21.1 13.1 0.6 0.5 0.3 0.7 0.4 0.7 0.4 0.6 0.8 0.6 1.3 0.9 0.5 0.6 0.3 0.5 0.3 0.8 0.3 17.0 16.9 18.2 18.7 15.2 18.8 15.5 19.1 17.5 16.8 20.5 18.8 18.6 16.0 14.5 33.0 17.8 24.0 11.5 12.6 13.6 23.3 21.3 14.7 13.7 17.2 12.2 62.5 14.6 11.8 23.1 23.9 23.5 11.9 0.6 20.6 27.3 15.7 16.8 9.4 25.9 18.7 13.0 11.7 18.3 31.5 9.5 16.8 14.6 18.8 17.6 33.7 24.5 17.0 16.2 21.4 27.0 3.9 11.8 15.7 10.6 15.9 14.6 20.0 22.6 26.2 21.6 15.4 18.9 14.7 20.2 14.6 14.2 34.8 10.3 16.9 26.3 17.1 13.7 4.1 9.7 21.0 26.3 14.6 15.9 21.6 15.9 15.5 FAM210A "C18orf19, HsT2329, MGC24180" ENSG00000177150 "Family with sequence similarity 210 member A" Q96ND0 18 13663347-13726663 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 33.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014324, HPA051564" Uncertain Approved "Nucleoplasm,Golgi apparatus,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Golgi apparatus, Mitochondria" "HPA014324: AB_2668972, HPA051564: AB_2681536" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (5.78e-2)" "unprognostic (9.18e-3)" "unprognostic (4.13e-2)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.23e-3)" "unprognostic (1.11e-2)" "unprognostic (2.26e-1)" "unprognostic (5.53e-3)" "unprognostic (6.79e-3)" "unprognostic (2.98e-2)" "unprognostic (3.27e-3)" "unprognostic (7.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" "unprognostic (4.82e-2)" 6.1 4.7 4.7 5.5 4.5 3.5 4.8 5.8 7.1 4.2 8.0 6.9 9.3 3.9 2.9 8.8 4.2 4.0 21.8 4.6 5.3 9.4 13.2 4.0 6.4 5.2 7.0 5.6 3.3 6.4 2.6 7.5 5.6 4.4 6.4 11.5 5.1 4.6 25.5 3.3 6.2 6.2 5.1 3.7 4.7 8.4 6.3 5.3 6.3 33.1 7.3 6.3 5.0 5.7 24.6 13.6 9.4 8.8 10.9 11.2 13.6 16.5 15.3 18.2 21.1 18.4 11.6 24.9 20.2 11.8 33.6 11.5 18.2 20.6 29.5 17.4 8.4 17.7 9.7 13.0 12.9 30.3 15.9 9.7 15.9 17.5 61.6 12.7 11.9 14.8 24.2 13.4 21.2 16.8 18.7 19.5 10.6 47.7 13.5 15.2 22.3 29.1 15.1 15.3 6.0 10.1 14.5 21.1 40.0 13.4 10.8 14.2 13.2 46.4 45.7 29.1 20.6 15.1 20.1 28.8 24.6 15.6 18.9 3.5 5.3 3.3 6.2 8.0 6.8 5.7 5.2 5.4 6.4 6.3 6.4 6.2 0.8 6.0 4.2 4.0 5.4 3.8 4.7 4.5 5.8 7.1 4.6 5.3 5.2 7.0 5.6 5.1 6.3 5.7 14.9 9.6 8.3 13.7 29.8 55.3 14.8 28.3 12.5 63.2 11.0 11.2 66.4 12.8 14.6 7.3 20.9 20.6 11.6 9.1 21.5 18.6 20.5 16.7 21.6 18.3 11.4 5.9 18.0 8.8 39.0 17.4 10.2 32.7 7.0 36.7 6.8 20.7 20.0 30.3 23.5 10.0 10.2 9.5 43.4 6.1 9.3 26.5 8.8 15.0 11.4 19.0 15.5 18.6 24.8 12.6 4.1 10.1 14.2 19.9 12.1 29.8 5.0 29.9 6.6 16.3 15.4 31.4 32.3 20.6 57.3 25.7 16.8 45.6 20.5 14.8 FAM219A "bA573M23.5, C9orf25, FLJ39031" ENSG00000164970 "Family with sequence similarity 219 member A" Q8IW50 9 34398184-34458570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 94.6" "Cell type enhanced" "Detected in many" "Horizontal cells: 53.8;Late spermatids: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019338, HPA052909" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA019338: AB_1845819, HPA052909: AB_2681986" "unprognostic (9.96e-3)" "unprognostic (2.16e-1)" "unprognostic (1.50e-2)" "unprognostic (1.23e-2)" "unprognostic (6.81e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.98e-5)" "unprognostic (2.71e-2)" "unprognostic (2.50e-1)" "unprognostic (2.95e-1)" "prognostic favorable (2.46e-4)" "unprognostic (3.46e-3)" "prognostic unfavorable (5.54e-5)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.34e-1)" "unprognostic (2.76e-1)" 19.8 14.0 82.5 9.0 79.4 3.8 17.5 72.4 88.0 18.5 25.9 17.0 5.4 22.5 6.2 9.8 15.7 5.6 29.9 75.9 77.5 15.7 12.7 18.8 6.5 90.0 84.8 15.3 13.2 6.4 26.3 13.4 94.6 16.3 4.6 19.3 12.1 7.0 42.7 16.2 11.9 11.9 83.8 15.1 12.7 9.7 82.9 8.3 14.9 12.6 5.0 17.7 15.7 85.4 27.9 10.6 24.5 14.0 22.3 8.5 23.8 16.5 12.4 14.0 17.7 7.4 6.3 6.1 16.6 16.1 27.7 11.4 19.6 10.6 14.0 96.0 11.2 2.5 14.6 8.0 12.5 6.1 13.6 9.0 10.5 21.0 11.7 17.4 23.4 10.6 6.1 29.6 11.0 5.6 9.5 8.5 15.8 3.8 15.6 12.1 4.1 5.3 10.1 5.9 7.8 24.8 14.3 10.3 8.5 22.2 5.2 6.1 28.0 15.4 11.9 32.3 23.2 7.8 12.0 5.1 44.2 13.9 27.8 0.6 0.1 1.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.5 0.2 0.2 0.1 0.4 0.1 82.5 79.4 72.4 88.0 75.9 77.5 90.0 84.8 94.6 83.8 82.9 85.4 14.3 6.4 3.3 17.3 3.3 6.2 3.7 5.6 4.0 21.1 5.1 2.9 11.7 1.5 2.5 3.7 4.2 9.4 4.3 2.1 0.0 6.1 13.8 2.0 6.0 17.4 10.8 0.4 28.6 5.1 16.8 7.8 6.1 2.8 2.5 3.4 9.3 2.8 5.9 53.8 31.8 2.3 8.2 5.5 2.6 35.1 3.7 4.1 8.8 15.0 4.5 9.3 3.1 22.1 15.9 6.6 1.7 5.7 3.0 5.1 1.3 3.0 2.3 11.0 6.6 5.2 9.1 9.9 3.8 3.0 6.5 20.7 3.5 2.9 0.9 2.7 FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Early spermatids: 29.1;Horizontal cells: 77.4;Oligodendrocytes: 78.5;Rod photoreceptor cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" 0.7 19.0 23.7 0.7 45.2 0.6 1.2 36.7 34.2 0.6 5.6 1.9 4.8 0.3 0.8 2.3 0.4 0.8 8.9 20.0 27.6 10.6 4.0 2.1 0.4 41.2 43.1 13.4 3.9 0.7 22.4 0.1 37.7 1.8 1.0 22.1 3.4 0.5 4.3 3.2 2.2 0.4 29.0 6.2 7.2 23.4 48.4 0.4 0.7 0.6 0.6 0.9 1.8 65.6 2.0 3.1 1.6 3.7 1.0 0.0 1.1 0.6 0.3 1.6 0.2 28.1 0.5 0.3 2.2 0.8 1.7 1.2 1.9 0.1 0.6 16.8 4.0 3.5 0.9 6.5 0.2 2.8 3.6 0.2 0.2 0.3 0.0 0.4 0.1 2.0 1.2 0.6 0.3 11.5 0.7 3.6 3.0 3.3 5.3 2.3 8.0 1.2 3.5 1.5 19.2 116.4 2.5 3.7 8.2 0.5 4.5 3.0 0.2 0.5 3.2 1.3 2.4 2.9 4.0 2.4 0.3 2.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 45.2 36.7 34.2 20.0 27.6 41.2 43.1 37.7 29.0 48.4 65.6 2.1 0.0 0.0 2.3 3.6 2.2 0.9 0.1 3.4 23.4 7.4 6.1 8.1 1.5 0.8 1.8 33.3 0.3 10.4 1.2 7.9 1.7 29.1 1.2 0.5 1.3 7.7 0.0 1.3 0.8 0.2 1.5 1.5 1.8 0.0 0.7 0.7 1.3 0.3 77.4 6.7 5.8 0.0 0.0 2.1 13.4 1.2 1.9 7.2 0.0 0.1 11.2 0.0 9.5 78.5 1.1 0.2 0.4 1.3 1.7 0.9 0.7 0.6 50.3 0.0 2.6 1.5 1.1 5.7 3.3 1.8 0.8 3.7 6.0 1.6 0.4 FAM229B "C6orf225, DKFZp586F0922, LOC619208" ENSG00000203778 "Family with sequence similarity 229 member B" Q4G0N7 6 112087591-112102790 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 448.1" "Group enriched" "Detected in many" 8 "Early spermatids: 3403.2;Late spermatids: 7607.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA036068 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA036068: AB_10673495" "unprognostic (1.65e-1)" "unprognostic (9.41e-2)" "unprognostic (4.29e-2)" "unprognostic (4.67e-3)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (2.71e-2)" "unprognostic (1.76e-2)" "unprognostic (5.08e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-3)" "unprognostic (4.74e-2)" "prognostic favorable (8.76e-4)" "unprognostic (3.74e-3)" "unprognostic (1.36e-1)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" 18.2 21.7 62.1 3.6 69.4 3.7 16.9 68.5 85.4 20.7 67.9 21.1 3.5 25.8 36.4 7.2 53.4 19.1 69.9 60.5 68.7 29.2 25.0 15.3 3.5 70.0 69.7 25.9 8.6 43.6 66.1 10.6 71.3 19.2 5.4 35.4 9.0 22.6 13.6 7.7 7.4 18.4 72.8 5.2 18.7 448.1 65.2 10.9 21.1 15.3 3.3 19.0 11.3 77.1 4.0 9.9 39.9 19.5 34.3 34.0 1.9 14.9 56.6 21.0 44.0 1.7 9.4 3.1 43.0 27.7 21.9 2.5 8.4 21.7 33.4 1.0 27.7 3.7 4.1 15.7 21.3 8.1 1.8 20.7 14.3 34.8 5.9 48.6 20.9 35.2 4.9 7.8 26.0 1.0 15.1 12.9 10.4 2.9 23.2 23.3 10.0 3.2 31.3 0.6 37.0 15.5 11.9 1.3 23.9 21.4 19.1 7.4 12.0 17.5 7.4 67.1 20.2 5.8 0.3 28.6 27.7 6.8 23.5 0.1 0.0 2.1 3.0 0.0 3.9 1.8 2.6 2.4 0.4 2.6 5.6 5.1 0.2 4.6 0.2 2.5 0.3 1.9 62.1 69.4 68.5 85.4 60.5 68.7 70.0 69.7 71.3 72.8 65.2 77.1 53.7 3.2 11.4 10.4 4.7 8.4 18.8 48.6 12.0 31.3 23.6 34.7 93.9 21.5 42.1 51.5 12.5 1.5 1.9 0.3 133.1 31.7 3403.2 207.7 18.5 24.6 3.0 9.0 17.2 10.4 6.9 32.9 7.1 11.6 1.3 36.1 33.2 54.4 3.1 16.8 14.8 0.6 52.9 3.2 7.3 7607.9 72.7 6.2 24.9 6.5 2.1 83.5 4.1 12.1 35.8 6.7 0.1 90.7 5.0 11.6 0.1 93.0 409.9 36.9 59.2 26.5 32.6 663.2 51.1 5.5 8.7 0.5 4.4 64.0 0.7 12.2 FAM241B C10orf35 ENSG00000171224 "Family with sequence similarity 241 member B" Q96D05 10 69630247-69633596 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.4;Collecting duct cells: 16.5;Distal tubular cells: 11.7;Ductal cells: 24.3;Exocrine glandular cells: 18.4;Pancreatic endocrine cells: 20.7;Proximal tubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "gdT-cell: 4.3;MAIT T-cell: 10.9;memory CD4 T-cell: 10.5;memory CD8 T-cell: 7.0;naive CD4 T-cell: 17.2;naive CD8 T-cell: 5.7;T-reg: 7.8" "Lineage enriched" "Detected in single" 25 "T-cells: 17.2" "Cell line enhanced" "Detected in many" "PC-3: 57.5" "Low region specificity" "Detected in all" HPA034591 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Centrosome" Cytosol "HPA034591: AB_10670572" "unprognostic (1.12e-1)" "unprognostic (6.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.17e-1)" "unprognostic (7.17e-3)" "prognostic unfavorable (8.64e-4)" "prognostic unfavorable (1.03e-4)" "unprognostic (3.56e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.63e-1)" "unprognostic (3.37e-2)" "unprognostic (3.12e-2)" "unprognostic (5.23e-2)" "unprognostic (2.52e-1)" "prognostic favorable (9.72e-4)" 1.6 3.0 26.3 1.9 27.3 1.1 4.7 30.4 40.3 2.2 19.2 6.6 2.7 3.2 11.1 4.8 4.3 2.0 6.6 35.5 31.7 10.7 3.7 4.0 2.9 21.7 24.2 2.1 8.2 8.2 12.7 1.2 28.2 7.8 2.3 11.3 5.5 4.7 4.7 3.4 3.5 3.8 21.5 1.4 5.8 22.2 26.4 2.8 5.8 1.2 2.3 5.8 3.0 22.2 29.4 31.9 3.9 31.8 0.0 0.0 13.6 2.9 0.8 5.1 5.6 23.4 23.6 0.0 42.8 0.6 18.6 11.8 16.6 9.6 7.1 29.4 22.8 0.0 6.7 8.8 8.1 0.0 10.0 0.0 9.4 0.2 4.8 3.8 0.0 43.8 11.1 0.1 0.5 39.9 0.3 0.0 19.1 11.8 57.5 0.0 0.0 0.4 10.9 16.6 16.0 22.2 12.1 29.6 19.0 7.8 20.5 5.1 1.4 0.8 19.4 0.1 8.5 5.1 15.2 0.1 0.4 0.0 0.8 0.0 0.0 0.0 4.3 0.0 10.9 0.1 10.5 7.0 0.1 0.4 17.2 5.7 0.6 0.2 0.0 0.1 7.8 3.1 26.3 27.3 30.4 40.3 35.5 31.7 21.7 24.2 28.2 21.5 26.4 22.2 1.4 0.0 4.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.3 19.4 0.0 0.0 3.1 16.5 0.0 7.5 0.6 0.0 11.7 24.3 0.0 5.7 0.4 0.7 0.0 0.0 0.0 18.4 5.6 0.6 0.0 5.0 0.0 8.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.3 0.0 0.0 13.5 4.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.9 2.8 3.7 0.0 0.0 FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" Yes No 15000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: AB_2683303" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.19e-2)" "unprognostic (4.73e-2)" "unprognostic (5.19e-2)" "unprognostic (2.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (6.27e-2)" "unprognostic (3.42e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (4.04e-1)" "unprognostic (9.71e-2)" 28.4 37.3 43.5 11.3 49.1 11.3 27.6 50.8 51.3 44.6 38.8 35.3 28.0 36.0 7.7 41.3 38.9 8.4 58.7 40.6 45.8 38.6 63.1 26.8 9.4 52.2 47.6 51.5 52.0 14.8 40.9 10.1 47.8 39.1 6.8 6.1 28.5 12.7 36.8 31.1 33.8 7.4 46.9 28.2 36.1 10.0 46.4 12.1 39.9 13.7 5.5 35.8 35.3 58.1 44.4 41.1 10.3 34.5 30.3 15.4 28.8 22.3 15.1 14.8 17.6 19.1 26.2 28.5 109.2 36.8 29.0 31.6 16.2 19.3 3.6 23.4 21.7 11.2 36.9 13.8 47.2 7.6 17.6 19.0 17.5 30.7 21.4 17.7 10.5 18.1 21.6 20.5 17.3 46.3 14.2 32.7 4.6 47.8 52.4 17.3 10.4 79.6 16.6 18.0 20.4 15.6 10.3 24.4 37.3 7.4 18.7 11.8 12.0 19.9 12.0 54.7 30.6 77.6 46.5 36.0 36.4 19.6 20.8 23.4 10.8 15.2 13.4 12.7 13.2 6.1 8.6 9.6 11.0 8.7 10.0 12.0 5.8 10.6 11.3 14.6 9.1 10.1 43.5 49.1 50.8 51.3 40.6 45.8 52.2 47.6 47.8 46.9 46.4 58.1 23.5 12.8 16.7 13.1 16.9 16.3 23.4 29.2 22.8 25.4 21.9 24.9 21.9 22.8 16.3 22.0 14.6 47.0 19.3 60.2 27.4 27.6 1.0 13.4 18.3 18.3 17.5 29.9 7.1 42.5 50.0 28.4 50.0 15.0 5.7 34.8 23.6 30.3 29.8 21.9 9.4 58.9 18.3 16.4 15.3 2.8 33.5 18.0 33.8 6.5 17.6 28.9 24.7 11.1 14.3 28.2 57.5 29.3 32.5 28.7 116.2 33.1 12.7 20.4 6.6 26.7 24.5 5.2 10.1 32.1 21.2 71.3 19.3 23.7 39.7 22.9 FAM50B "D6S2654E, X5L" ENSG00000145945 "Family with sequence similarity 50 member B" Q9Y247 6 3849373-3851320 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 88.3;MCF7: 27.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA064111, HPA067817" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Midbody" Yes NA "Cluster 15: NK-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Midbody" "HPA064111: AB_2685191, HPA067817: AB_2685904" "unprognostic (1.15e-1)" "unprognostic (7.76e-2)" "unprognostic (4.28e-2)" "unprognostic (4.43e-2)" "unprognostic (2.12e-3)" "unprognostic (2.69e-1)" "unprognostic (2.38e-2)" "unprognostic (7.13e-2)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (2.15e-1)" "unprognostic (2.90e-1)" "prognostic favorable (4.01e-6)" "unprognostic (1.60e-1)" "unprognostic (3.22e-1)" "unprognostic (1.34e-1)" "unprognostic (9.39e-2)" 6.9 9.1 11.7 3.7 14.3 1.8 7.0 12.3 15.1 8.3 8.5 10.2 6.6 9.7 3.9 6.6 8.8 3.7 18.0 12.5 13.6 9.8 12.9 5.3 5.1 11.7 11.1 9.3 9.2 4.2 10.4 1.7 11.5 6.4 1.4 5.5 10.2 5.8 32.1 7.1 6.5 2.8 11.2 7.1 8.1 14.0 13.0 3.9 9.8 8.8 3.5 9.7 6.3 12.6 6.6 8.7 0.1 0.0 4.9 4.7 0.4 7.6 3.7 5.1 6.5 0.0 11.7 7.0 8.0 5.5 2.0 4.9 0.0 3.0 3.8 88.3 4.6 0.0 21.1 0.0 5.2 0.0 0.1 5.2 6.0 4.0 1.1 1.6 5.1 0.0 0.0 0.0 4.6 27.5 0.0 9.8 1.9 4.0 4.1 0.0 0.0 0.0 2.5 0.0 11.8 10.3 12.4 7.7 0.4 0.0 8.4 7.8 7.2 0.0 0.9 10.1 0.0 0.0 19.7 0.0 2.7 0.6 14.1 5.7 7.9 4.4 11.3 10.8 26.7 25.0 21.8 14.6 10.5 20.8 17.7 11.2 3.3 33.8 17.7 17.3 36.0 9.0 11.7 14.3 12.3 15.1 12.5 13.6 11.7 11.1 11.5 11.2 13.0 12.6 11.4 16.0 7.0 2.6 8.3 6.4 5.7 10.2 15.4 18.1 8.7 13.5 19.8 17.2 8.3 12.9 4.2 4.2 9.3 2.3 33.2 13.5 31.5 6.8 5.0 6.7 1.2 6.7 2.5 11.1 6.9 8.0 7.1 3.3 3.8 7.5 11.0 21.6 10.1 15.2 2.6 3.5 8.2 6.8 4.7 28.8 8.4 5.6 12.4 1.0 8.7 20.9 4.1 1.0 4.6 8.5 5.1 10.9 6.9 3.3 7.4 36.9 6.8 16.0 0.0 13.0 8.4 38.3 43.9 12.5 6.7 1.0 6.1 7.8 3.8 2.1 FAM72A "LMPIP, MGC57827, p17, RP11-312O7.1, UGENE" ENSG00000196550 "Family with sequence similarity 72 member A" Q5TYM5 1 206186179-206204414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Early spermatids: 29.5;Kupffer cells: 18.2;Late spermatids: 30.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (3.61e-2)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" "unprognostic (5.20e-5)" "unprognostic (3.61e-1)" "unprognostic (1.19e-3)" "unprognostic (1.01e-5)" "unprognostic (7.70e-3)" "unprognostic (1.45e-2)" "unprognostic (5.58e-3)" "unprognostic (2.87e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-16)" "unprognostic (1.82e-1)" "unprognostic (1.94e-2)" "unprognostic (4.83e-2)" "unprognostic (3.89e-1)" 4.0 3.1 2.6 5.9 2.9 8.4 3.6 9.1 3.1 1.3 1.0 2.2 3.1 0.9 0.4 2.5 1.8 2.7 1.2 3.1 4.0 1.3 2.0 2.6 10.9 5.4 4.4 1.1 1.4 1.6 0.8 3.5 5.8 1.1 2.3 0.2 1.0 0.7 0.6 5.9 2.9 2.0 4.1 6.3 1.5 7.1 4.8 8.6 0.9 1.0 7.5 1.5 1.5 4.7 21.1 16.4 17.7 7.7 2.6 3.1 21.1 14.6 6.3 17.1 12.7 9.9 31.1 54.2 12.3 3.8 18.8 24.7 20.9 8.1 20.2 29.5 16.3 24.3 16.4 13.9 1.8 42.9 27.0 4.4 1.4 15.1 26.7 5.1 10.7 45.7 50.1 36.7 10.7 12.9 26.9 38.3 32.1 15.1 22.1 29.5 30.6 41.4 9.8 3.2 17.7 10.2 10.6 9.7 9.3 20.1 20.5 23.2 5.5 13.5 15.5 17.7 24.9 29.1 44.8 48.4 11.1 34.9 18.8 0.0 5.9 0.0 0.7 8.0 0.2 1.7 1.4 1.4 4.6 0.5 0.1 0.3 1.0 0.6 4.8 1.9 2.9 2.1 2.6 2.9 9.1 3.1 3.1 4.0 5.4 4.4 5.8 4.1 4.8 4.7 5.9 0.0 1.5 0.0 2.4 1.8 0.4 1.2 1.2 0.3 0.8 0.6 1.5 0.0 0.9 0.0 0.0 0.8 3.7 4.9 0.0 1.0 29.5 1.5 1.5 8.4 0.0 0.4 0.1 0.8 3.8 1.8 0.5 0.7 0.0 0.3 7.1 0.4 9.4 0.0 0.2 3.6 0.0 18.2 5.8 30.2 0.0 6.9 3.6 0.0 9.6 0.6 2.1 0.0 0.1 0.6 0.0 0.0 1.6 0.4 1.3 0.3 2.1 0.2 0.0 0.9 2.2 28.0 4.1 2.0 1.0 0.7 1.4 0.8 1.6 0.8 FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.3;Early spermatids: 11.3;Erythroid cells: 5.9;Hepatic stellate cells: 6.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (8.53e-2)" "unprognostic (1.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.25e-3)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-4)" "unprognostic (8.22e-5)" "unprognostic (1.30e-2)" "unprognostic (1.79e-2)" "unprognostic (1.36e-4)" "unprognostic (2.46e-2)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-2)" "unprognostic (5.30e-2)" 0.8 0.6 1.2 3.7 1.0 6.2 0.8 2.0 1.1 0.5 1.3 1.1 1.3 0.5 0.4 1.6 0.4 1.0 0.3 1.2 1.2 0.4 0.4 0.6 8.1 1.6 1.4 0.4 0.2 0.7 0.2 1.4 1.6 0.2 1.2 0.1 0.4 0.2 0.1 1.9 1.1 0.7 1.3 2.0 1.0 2.3 1.3 10.3 0.3 0.2 6.6 0.8 0.7 1.4 28.6 10.3 16.5 8.2 1.6 2.4 13.3 14.7 6.2 16.8 14.1 0.1 14.5 62.9 19.9 2.7 16.4 17.1 23.1 8.3 25.9 41.1 17.3 27.2 12.0 12.5 1.0 47.7 23.2 1.3 0.9 13.0 26.5 4.2 10.3 51.0 36.1 37.3 12.4 12.1 24.1 39.1 31.6 14.9 20.6 35.8 35.8 28.7 6.7 3.2 18.0 10.4 11.1 8.6 8.6 16.9 11.4 36.5 3.6 13.8 23.5 27.3 26.6 32.6 44.1 61.3 12.4 50.8 32.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.4 0.3 1.2 1.0 2.0 1.1 1.2 1.2 1.6 1.4 1.6 1.3 1.3 1.4 1.3 0.0 0.0 0.0 1.6 1.0 0.1 0.2 0.0 0.0 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.8 0.1 7.3 0.0 0.2 11.3 0.2 0.4 2.5 0.0 5.9 0.1 0.2 2.3 0.6 1.1 0.2 0.0 0.5 6.4 0.0 1.1 0.0 0.3 4.9 0.0 1.9 2.8 3.0 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.1 2.3 0.0 2.5 0.0 2.1 0.0 0.7 0.0 0.0 0.3 0.9 17.0 3.1 3.5 1.0 0.1 1.2 0.2 3.6 0.0 FAM72C RP5-998N21.9 ENSG00000263513 "Family with sequence similarity 72 member C" H0Y354 1 143955364-143971965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.9;lymphoid tissue: 5.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 7.8;Extravillous trophoblasts: 4.5;Sertoli cells: 6.6;Spermatocytes: 9.4;Spermatogonia: 3.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 64.9" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (6.45e-3)" "unprognostic (2.69e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-3)" "unprognostic (9.46e-5)" "unprognostic (1.23e-3)" "unprognostic (4.36e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-1)" "unprognostic (0.00e+0)" "unprognostic (2.95e-1)" "unprognostic (4.70e-2)" "unprognostic (5.82e-2)" "unprognostic (1.47e-2)" 0.4 0.2 0.1 1.5 0.1 2.9 0.3 0.2 0.2 0.2 0.0 0.4 0.6 0.2 0.0 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.3 4.5 0.1 0.1 0.1 0.2 0.0 0.0 0.5 0.1 0.1 0.6 0.0 0.2 0.0 0.0 1.2 0.4 0.3 0.1 1.2 0.3 1.6 0.1 5.4 0.1 0.1 4.5 0.4 0.4 0.2 18.7 10.6 12.5 5.7 0.6 1.7 12.1 8.9 2.8 12.0 9.0 1.6 21.7 44.4 11.6 1.0 11.0 17.4 17.2 5.5 13.0 15.3 10.0 19.1 9.4 3.3 0.4 39.5 16.6 0.3 0.1 9.1 24.3 2.5 5.1 34.7 34.0 20.5 0.8 1.4 23.2 30.4 10.2 20.8 6.6 29.7 9.0 31.5 2.1 2.3 6.3 11.5 8.7 5.0 4.9 13.0 12.5 33.4 3.7 9.4 15.4 12.5 20.3 41.9 64.9 26.0 5.1 24.1 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.6 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 2.3 0.3 0.2 1.3 0.0 7.8 0.2 0.2 4.5 0.3 0.0 0.1 0.0 0.5 1.8 0.1 1.7 0.0 0.3 0.6 0.0 2.2 1.4 0.5 0.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 6.6 0.3 0.7 9.4 3.5 1.3 0.3 0.3 0.7 0.3 0.5 0.0 FAM72D ENSG00000215784 "Family with sequence similarity 72 member D" Q6L9T8 1 145095974-145112696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;lymphoid tissue: 6.7" "Group enriched" "Detected in some" 4 "Early spermatids: 7.3;Erythroid cells: 9.7;Extravillous trophoblasts: 5.5;Spermatocytes: 15.4;Spermatogonia: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.70e-2)" "unprognostic (1.64e-1)" "unprognostic (1.73e-1)" "unprognostic (4.03e-3)" "unprognostic (1.26e-1)" "unprognostic (7.10e-3)" "unprognostic (5.88e-5)" "unprognostic (7.65e-4)" "unprognostic (6.72e-2)" "unprognostic (2.36e-2)" "unprognostic (1.22e-2)" "unprognostic (1.46e-1)" "unprognostic (0.00e+0)" "unprognostic (6.63e-2)" "unprognostic (1.72e-1)" "unprognostic (9.74e-2)" "unprognostic (6.50e-2)" 0.7 0.3 0.4 3.0 0.4 4.0 0.5 0.7 0.5 0.3 0.2 0.8 1.0 0.3 0.1 1.1 0.2 0.5 0.2 0.4 0.8 0.2 0.3 0.5 4.8 0.6 0.7 0.2 0.1 0.2 0.1 1.1 0.6 0.1 1.0 0.1 0.2 0.1 0.0 1.9 1.3 0.5 0.4 1.2 0.6 2.1 0.7 6.7 0.2 0.1 4.5 0.6 0.4 0.5 16.6 10.4 11.7 4.5 0.5 1.0 12.4 9.8 3.0 11.1 7.1 7.5 14.7 26.6 9.3 1.5 11.1 17.3 13.6 3.0 12.8 22.6 14.1 13.6 5.8 9.7 0.6 24.0 14.2 0.8 1.1 9.4 16.9 2.0 5.6 33.0 26.8 34.9 7.2 12.4 16.6 22.5 21.1 20.3 14.4 13.9 14.3 30.7 4.0 2.2 10.9 9.1 7.3 6.3 4.4 13.9 17.2 15.7 2.7 8.3 9.6 7.3 16.7 27.0 46.5 39.3 0.2 18.7 10.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.4 0.7 0.5 0.4 0.8 0.6 0.7 0.6 0.4 0.7 0.5 2.0 0.0 0.0 0.0 0.8 1.0 0.0 0.2 1.2 0.0 0.2 0.4 1.1 0.0 0.2 0.0 0.0 1.2 0.1 0.8 0.0 0.1 7.3 0.2 0.3 2.1 0.0 9.7 0.3 0.0 5.5 0.8 0.0 0.2 0.0 0.3 0.4 0.1 1.5 0.0 0.5 0.8 0.0 1.0 1.0 0.6 0.0 1.8 1.8 1.0 0.8 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.8 0.2 0.3 0.1 0.3 0.0 0.0 0.5 0.8 15.4 4.5 1.6 1.0 0.3 0.4 0.1 1.4 0.1 FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 84.7;intestine: 83.1;smooth muscle: 95.3" "Group enriched" "Detected in many" 4 "Basal squamous epithelial cells: 44.9;Erythroid cells: 72.6;Extravillous trophoblasts: 67.5;Squamous epithelial cells: 71.7;Syncytiotrophoblasts: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: AB_2680717, HPA060854: " "unprognostic (7.90e-3)" "unprognostic (4.34e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.44e-6)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.73e-5)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.81e-14)" "unprognostic (2.57e-3)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" 1.6 1.8 0.8 7.2 1.6 23.3 1.1 0.9 1.4 4.1 0.2 83.1 8.4 1.0 1.6 84.7 1.0 13.6 1.0 0.9 0.5 5.7 3.7 5.2 4.5 0.5 0.4 0.5 0.4 0.2 0.4 3.4 0.5 16.2 8.6 0.2 7.8 1.7 0.2 10.2 34.7 95.3 0.5 1.9 44.9 5.0 0.5 6.6 1.0 0.2 12.2 27.0 17.1 0.9 112.2 67.3 52.0 44.0 5.8 6.5 93.6 49.3 30.2 94.7 57.4 103.4 49.7 28.3 47.6 32.1 73.4 93.1 71.8 83.9 87.9 9.4 28.6 32.6 50.7 75.2 4.7 14.6 16.5 3.3 4.2 54.6 31.4 11.4 52.7 12.3 29.6 39.5 54.4 59.7 22.7 21.3 43.2 64.4 85.1 21.8 96.0 15.6 27.6 28.0 24.3 40.2 143.0 117.4 20.6 48.1 73.6 14.9 25.4 62.4 76.4 71.6 110.1 12.0 19.6 29.0 28.1 21.2 46.7 0.0 0.0 0.0 0.2 0.1 0.9 0.6 1.0 1.1 0.0 1.1 1.1 1.4 0.0 1.1 0.1 0.0 2.0 0.5 0.8 1.6 0.9 1.4 0.9 0.5 0.5 0.4 0.5 0.5 0.5 0.9 3.9 0.0 1.3 0.3 2.3 2.3 5.8 7.0 44.9 0.0 2.8 9.0 0.8 1.5 18.0 0.0 0.0 17.3 6.3 6.5 0.0 0.1 0.5 1.1 1.6 2.2 1.8 72.6 3.7 0.0 67.5 2.7 18.3 2.1 0.0 8.2 1.8 5.7 4.8 0.0 1.2 6.0 4.1 1.6 0.5 0.6 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 6.0 0.0 12.5 1.6 1.7 8.3 4.5 0.0 19.7 0.3 4.0 15.7 18.3 71.7 1.8 152.6 5.2 0.3 10.2 4.1 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403135-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 26: Non-specific - Mitochondria" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" Cytosol "HPA040930: AB_10795484, HPA041730: AB_10804114" "unprognostic (3.01e-2)" "unprognostic (6.44e-3)" "unprognostic (5.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.18e-1)" "unprognostic (8.10e-3)" "unprognostic (3.06e-1)" "unprognostic (2.15e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (8.51e-5)" "unprognostic (2.82e-2)" "unprognostic (8.91e-3)" "unprognostic (1.01e-1)" "unprognostic (2.37e-3)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "prognostic favorable (5.53e-4)" 10.6 9.6 14.5 5.5 13.9 8.7 12.3 12.3 17.6 14.8 7.2 14.6 13.8 10.7 2.6 17.7 12.3 5.3 11.6 13.8 11.7 12.2 13.3 9.1 6.2 18.9 11.6 12.5 18.6 8.4 11.6 2.3 13.5 13.4 4.7 1.7 13.9 5.8 3.3 25.2 15.4 3.3 12.7 11.8 14.4 9.0 14.4 4.7 11.4 2.5 3.8 12.7 14.6 14.3 15.6 16.3 1.9 9.4 2.0 6.8 8.2 8.8 7.3 8.5 8.9 2.8 11.0 13.9 9.7 5.2 3.0 7.5 3.7 6.3 1.4 22.6 7.6 4.6 2.9 6.5 9.0 3.9 8.1 6.6 13.0 4.3 7.8 4.7 5.0 22.5 12.9 15.0 5.1 17.2 5.9 3.1 1.4 25.5 17.5 11.6 3.9 8.4 10.4 8.0 3.3 9.6 8.8 15.6 5.6 0.9 11.8 12.3 6.7 3.8 10.4 11.9 10.7 16.1 8.8 6.1 9.9 9.2 6.2 0.0 1.9 10.8 2.4 2.7 3.2 2.0 4.2 3.4 2.6 6.5 3.3 2.6 1.7 3.0 2.7 1.0 3.9 1.4 14.5 13.9 12.3 17.6 13.8 11.7 18.9 11.6 13.5 12.7 14.4 14.3 19.8 9.6 8.9 3.6 17.5 21.5 22.3 23.7 14.8 15.1 21.1 26.3 5.4 10.0 21.2 23.9 12.5 11.8 22.1 41.4 21.5 22.2 6.4 18.2 9.1 12.0 25.7 9.7 11.7 32.9 10.9 13.9 17.9 18.0 15.2 8.6 11.4 12.5 11.0 11.8 9.5 32.4 22.4 13.2 18.2 2.4 18.6 14.3 23.2 2.8 14.4 14.6 34.0 5.5 8.5 23.8 42.8 18.4 12.7 12.2 100.4 22.6 22.4 12.5 13.1 13.5 13.8 37.4 37.4 22.3 29.8 6.2 21.8 12.9 34.8 23.4 FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30890559-30943108 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA048198: AB_2680311" "unprognostic (7.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.67e-2)" "prognostic favorable (1.42e-6)" "unprognostic (3.73e-1)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (1.29e-1)" 6.2 8.5 9.3 0.9 9.5 0.5 6.7 9.4 9.7 10.1 9.3 10.7 0.9 9.2 6.6 6.5 9.0 1.2 8.8 8.9 9.5 9.5 9.6 5.5 0.8 9.7 9.8 11.8 12.7 5.9 11.4 3.0 10.0 11.5 2.0 2.7 9.8 1.4 18.7 10.8 7.3 2.4 9.5 6.8 8.6 8.9 9.9 4.4 10.0 7.3 0.7 9.3 9.7 10.0 5.2 9.9 3.6 1.9 12.4 9.3 0.8 4.4 2.1 4.7 5.0 4.5 1.7 0.6 7.6 3.6 7.4 9.2 4.7 9.4 5.0 4.2 1.4 1.3 5.5 1.9 4.8 1.2 1.9 2.8 7.3 3.0 7.3 7.2 3.4 5.7 4.7 6.1 4.7 0.6 8.6 3.1 2.2 11.5 2.8 7.0 12.0 2.3 6.7 2.3 4.5 4.6 9.2 5.6 3.0 8.8 4.4 3.3 3.3 9.4 3.0 5.0 3.4 7.4 8.7 1.1 4.1 1.9 1.1 0.0 0.1 0.0 1.4 0.3 2.0 1.2 1.2 0.7 0.9 1.5 1.8 1.1 0.0 1.8 4.3 1.1 1.4 0.7 9.3 9.5 9.4 9.7 8.9 9.5 9.7 9.8 10.0 9.5 9.9 10.0 9.1 16.0 8.4 21.2 5.4 4.1 5.8 4.9 9.6 17.0 11.2 9.8 17.0 0.0 10.7 9.2 20.9 6.5 3.5 7.6 9.8 4.5 11.9 10.2 12.9 8.8 7.8 6.9 23.7 2.9 2.2 8.4 8.6 9.0 8.8 15.5 6.8 13.4 3.7 26.9 25.5 11.0 8.2 5.4 2.5 7.1 10.5 3.9 5.4 15.0 3.4 14.9 7.2 13.6 44.2 3.6 6.4 6.8 7.0 6.0 4.2 8.0 13.6 23.5 6.6 9.4 7.6 20.9 16.4 7.2 2.4 4.1 5.3 9.2 10.3 3.7 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FAU "asr1, FLJ22986, Fub1, Fubi, MNSFbeta, RPS30, S30" ENSG00000149806 "FAU ubiquitin like and ribosomal protein S30 fusion" "P35544, P62861" 11 65120630-65122177 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059015 Supported Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" No No "Cluster 30: Non-specific - Translation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA059015: AB_2683881" "unprognostic (1.81e-3)" "unprognostic (3.47e-2)" "unprognostic (2.89e-1)" "unprognostic (2.91e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-3)" "unprognostic (1.97e-1)" "unprognostic (5.40e-2)" "unprognostic (1.26e-1)" "unprognostic (7.06e-3)" "unprognostic (7.77e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-3)" "unprognostic (1.45e-2)" 817.0 787.0 976.0 655.4 1009.0 1898.7 878.5 956.5 1212.5 1024.2 887.1 905.9 604.0 780.6 535.3 720.0 907.5 590.1 862.2 928.0 953.5 632.1 756.3 614.0 1342.5 982.1 958.7 1403.7 1167.7 395.0 521.6 482.7 989.8 649.3 438.8 228.2 854.7 532.3 1191.2 905.1 712.9 441.6 1010.2 784.5 796.3 336.6 1011.9 843.5 619.9 642.1 818.5 796.7 794.0 1017.9 1305.1 1040.6 658.8 1067.9 766.4 1142.2 1033.3 727.3 887.7 1327.5 832.4 1258.7 1232.1 1782.0 1782.3 744.2 701.5 1101.2 821.5 1287.2 419.3 1075.4 1494.0 1428.1 907.1 1607.8 1612.2 1546.9 1184.9 1583.3 1944.0 1106.3 1286.5 842.2 998.5 1416.3 1334.4 1578.6 644.9 2003.0 1579.6 2925.2 1850.4 1007.2 2027.5 1464.8 622.2 2980.1 1036.0 744.3 1054.4 949.2 663.8 1490.6 2131.0 399.1 1393.3 1829.5 771.2 868.6 954.8 1327.5 1150.0 1629.0 1943.6 2802.6 1042.6 1285.4 979.3 2638.2 2997.4 1808.3 2906.6 2694.0 3986.3 7025.5 4689.8 3729.6 3181.0 6502.9 5484.9 4364.5 1905.5 2994.7 2398.9 4141.8 3794.9 10270.4 976.0 1009.0 956.5 1212.5 928.0 953.5 982.1 958.7 989.8 1010.2 1011.9 1017.9 2252.8 641.0 1035.7 17.6 3768.6 3773.3 3059.7 1883.6 2632.2 351.8 3483.5 5942.5 507.2 1712.8 1280.4 958.2 196.0 2277.7 2670.7 1454.5 2050.4 1540.6 875.1 954.7 1569.4 1671.7 1226.4 1786.0 15.9 2689.2 2487.3 1531.1 923.5 1298.4 1370.0 1483.3 1755.9 2176.7 2188.0 190.1 18.2 2143.3 907.3 2643.8 3977.8 2397.4 2285.9 2349.4 2123.8 16.9 3121.9 935.5 2472.7 15.6 40.8 2042.7 2666.5 1229.2 2317.3 3295.5 2501.4 2615.9 826.4 513.6 1117.5 2227.4 2678.6 654.4 590.6 2506.0 4195.9 2793.0 2897.4 1470.6 2184.8 3518.0 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FBRSL1 KIAA1545 ENSG00000112787 "Fibrosin like 1" Q9HCM7 12 132489551-132585188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NB-4: 90.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049880 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA049880: AB_2680930" "unprognostic (2.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-2)" "unprognostic (7.75e-2)" "unprognostic (3.21e-1)" "unprognostic (2.59e-2)" "unprognostic (1.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.25e-1)" "unprognostic (1.57e-1)" "unprognostic (2.77e-3)" "prognostic unfavorable (9.82e-4)" "prognostic favorable (1.17e-4)" "unprognostic (1.13e-1)" "unprognostic (3.39e-1)" "unprognostic (1.09e-2)" "prognostic favorable (7.21e-4)" 12.3 19.2 16.3 8.7 13.1 10.1 13.2 20.7 21.2 17.8 7.2 20.5 11.2 18.6 7.7 15.6 18.7 4.1 31.1 16.2 6.7 19.3 26.8 16.2 8.5 10.0 7.7 22.3 39.2 7.3 28.7 5.7 8.0 22.0 3.6 5.9 14.7 7.2 31.9 19.4 23.3 4.1 4.7 28.3 21.4 29.1 9.6 6.2 15.7 9.4 4.7 17.8 15.7 10.2 11.7 18.5 8.7 14.8 3.7 4.5 64.4 10.9 3.1 7.1 4.3 32.7 6.9 19.0 18.4 3.6 6.1 22.6 9.3 6.1 2.3 14.7 47.6 23.2 11.0 25.0 8.0 24.7 23.4 4.1 10.7 6.6 4.8 6.5 7.0 15.9 49.9 3.8 3.1 29.8 33.7 90.0 22.7 8.4 33.4 50.9 9.3 13.2 6.2 11.2 33.4 28.0 10.2 15.8 14.1 3.6 18.6 23.7 11.1 7.6 18.5 13.7 13.9 24.6 13.0 12.0 8.8 23.8 9.4 1.2 0.4 1.2 0.3 0.3 0.3 0.8 0.3 0.3 0.3 0.6 0.3 0.4 0.5 0.2 0.7 1.0 0.6 0.3 16.3 13.1 20.7 21.2 16.2 6.7 10.0 7.7 8.0 4.7 9.6 10.2 14.9 3.2 5.2 24.2 12.8 9.2 7.1 3.3 11.4 28.9 20.7 18.5 13.7 4.3 4.0 11.0 41.7 6.9 19.8 24.0 7.9 6.2 1.4 16.8 17.9 8.8 31.0 12.0 17.0 7.6 5.8 11.8 15.3 22.0 1.3 22.6 7.5 22.2 6.9 11.8 17.1 21.7 0.0 11.6 11.1 2.0 16.1 16.4 5.4 15.0 7.7 9.3 6.2 12.5 16.8 9.0 15.0 15.4 11.9 16.0 13.3 6.4 6.4 22.7 6.6 12.7 11.5 5.7 8.0 10.8 10.4 11.5 10.9 12.7 18.7 10.4 FBXL14 "Fbl14, MGC40195" ENSG00000171823 "F-box and leucine rich repeat protein 14" Q8N1E6 12 1565993-1594581 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 47.4;Late spermatids: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053889 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA053889: AB_2682293" "unprognostic (8.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.82e-1)" "unprognostic (4.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.27e-1)" "unprognostic (5.90e-2)" "unprognostic (8.98e-2)" "prognostic favorable (9.04e-6)" "unprognostic (5.60e-3)" "unprognostic (1.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.12e-3)" 5.2 4.3 7.9 5.9 10.6 5.8 4.6 8.7 21.4 3.6 2.4 8.4 4.9 4.5 1.6 6.0 5.7 4.8 5.2 10.6 7.8 4.6 3.9 5.7 7.5 7.8 8.1 4.7 11.3 7.1 8.7 4.2 8.3 3.7 3.5 4.2 6.2 4.0 3.3 3.4 6.2 2.1 7.4 6.4 9.7 21.1 9.0 8.3 6.4 2.5 3.3 4.7 4.3 8.6 11.8 16.3 4.8 8.4 4.0 4.1 14.3 2.6 4.7 2.4 2.7 17.1 14.8 15.8 3.1 2.9 4.0 8.1 3.9 6.0 0.4 27.2 19.0 19.6 4.7 5.5 5.3 15.0 14.4 6.5 2.7 4.4 3.7 4.3 4.3 13.4 8.3 43.2 2.9 12.4 15.9 7.4 21.2 6.4 6.7 13.5 7.8 9.9 3.8 10.3 9.2 9.1 6.3 9.5 9.8 4.9 7.5 12.1 6.4 5.3 17.5 6.8 9.5 5.3 6.1 19.7 11.3 8.7 8.2 0.7 0.1 0.0 0.1 0.1 0.1 0.2 0.4 0.4 0.2 1.7 0.4 0.2 0.3 0.6 0.2 0.2 1.6 0.1 7.9 10.6 8.7 21.4 10.6 7.8 7.8 8.1 8.3 7.4 9.0 8.6 1.9 0.0 0.0 11.4 1.1 0.0 0.3 0.5 1.8 4.2 1.1 0.9 0.9 0.0 0.3 0.0 0.0 0.2 0.5 1.6 0.0 0.2 47.4 1.7 0.8 2.3 0.0 0.4 12.3 0.5 0.1 1.3 1.5 0.9 0.0 0.5 2.9 1.1 0.6 10.1 13.4 0.7 2.0 0.8 0.8 103.7 0.3 1.2 0.0 12.2 0.8 2.7 0.0 10.6 17.1 0.1 0.7 1.5 1.8 0.8 1.4 0.8 1.0 3.0 0.0 1.7 1.1 10.4 0.5 2.9 0.0 0.1 1.8 0.9 1.2 0.3 FBXL2 "FBL2, FBL3" ENSG00000153558 "F-box and leucine rich repeat protein 2" Q9UKC9 3 33277025-33403662 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 48.8;Excitatory neurons: 125.0;Inhibitory neurons: 92.8;Late spermatids: 50.7;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 5.7;LHCN-M2: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003240, HPA061783" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003240: , HPA061783: AB_2684605" "unprognostic (5.73e-2)" "unprognostic (4.47e-2)" "unprognostic (7.92e-2)" "unprognostic (7.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (3.16e-1)" "unprognostic (2.00e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "prognostic favorable (3.35e-4)" "unprognostic (3.30e-3)" "unprognostic (9.72e-2)" "unprognostic (4.28e-2)" "unprognostic (5.90e-2)" 0.9 1.3 3.6 0.4 3.8 0.3 1.0 2.2 4.0 1.1 4.2 1.1 0.7 1.0 2.1 0.4 1.5 0.6 0.9 3.5 3.7 1.4 0.2 1.2 0.3 2.9 2.6 1.4 1.1 2.7 2.7 1.4 3.0 1.0 0.2 4.2 0.8 1.6 0.2 0.6 0.5 0.8 1.6 0.5 0.8 1.1 3.3 0.2 2.3 0.0 0.2 0.8 0.9 2.7 2.7 0.7 1.0 1.0 1.5 2.4 0.4 2.0 1.6 1.8 2.6 0.5 3.1 0.1 0.6 1.3 0.8 0.5 0.9 2.1 1.2 0.2 1.1 0.4 2.3 0.5 1.8 0.2 0.4 0.9 1.6 1.1 0.8 5.7 3.3 1.9 0.5 0.2 6.2 0.2 0.5 0.3 0.7 0.3 0.6 0.1 0.6 0.1 4.6 0.7 1.1 1.1 0.9 0.5 0.8 1.7 1.3 0.7 2.5 0.8 0.7 0.6 1.1 0.2 0.1 0.1 0.8 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 3.6 3.8 2.2 4.0 3.5 3.7 2.9 2.6 3.0 1.6 3.3 2.7 2.7 3.2 7.3 22.2 1.0 1.1 7.6 5.6 1.8 15.3 3.0 3.7 2.4 2.8 4.8 5.5 25.0 0.5 0.4 0.1 3.9 3.9 48.8 18.8 3.6 3.8 0.0 0.0 125.0 0.4 1.5 5.0 5.6 6.2 0.0 6.2 2.2 0.1 0.5 18.5 92.8 0.3 8.2 0.8 2.4 50.7 1.5 0.5 1.8 22.5 0.1 6.6 0.0 55.8 49.6 4.2 0.1 4.1 0.3 4.2 0.2 3.2 16.5 17.7 6.6 3.6 3.9 21.3 8.6 0.7 1.1 0.7 1.5 3.5 0.1 3.8 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO31 "FBX14, Fbx31, FBXO14, MGC15419" ENSG00000103264 "F-box protein 31" Q5XUX0 16 87326987-87392142 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 65.3" "Cell type enhanced" "Detected in many" "Adipocytes: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030150 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Golgi apparatus, Cytosol" "HPA030150: AB_10670559" "unprognostic (4.85e-1)" "unprognostic (5.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.53e-2)" "unprognostic (4.04e-1)" "unprognostic (2.25e-1)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.65e-2)" "prognostic favorable (9.16e-5)" "unprognostic (3.00e-2)" "unprognostic (1.47e-3)" "unprognostic (1.20e-1)" "unprognostic (3.95e-1)" "unprognostic (1.57e-3)" "unprognostic (2.26e-3)" 33.7 12.8 6.8 6.0 8.5 5.7 24.3 39.0 14.5 14.9 0.0 20.9 8.6 21.7 4.4 10.2 16.8 6.2 18.2 11.9 13.4 5.3 15.9 8.7 6.4 8.3 5.5 15.0 13.1 8.2 19.4 4.9 11.1 10.2 5.8 8.1 11.1 10.7 65.3 17.0 15.9 11.1 2.7 5.2 11.5 18.7 9.5 5.7 8.7 36.8 4.6 21.8 13.0 7.6 7.0 13.1 4.3 11.7 21.6 12.9 12.5 12.0 11.9 11.6 6.1 11.9 5.8 16.3 12.9 12.7 5.9 10.6 8.3 10.0 7.7 7.5 15.5 5.5 8.7 34.1 12.1 5.3 4.4 15.4 8.3 15.2 14.3 7.6 7.2 8.3 15.9 6.3 6.3 10.1 13.0 7.3 8.4 7.3 11.5 16.1 5.1 7.0 5.2 4.9 20.0 9.7 26.7 5.4 8.3 3.1 8.5 4.6 10.1 11.2 8.5 10.8 9.6 14.4 12.0 20.1 9.0 9.8 7.0 0.5 0.1 0.0 0.2 0.1 0.4 0.6 0.4 0.6 0.1 0.3 0.4 0.5 0.2 0.0 0.2 0.2 1.1 0.4 6.8 8.5 39.0 14.5 11.9 13.4 8.3 5.5 11.1 2.7 9.5 7.6 61.3 0.0 4.6 13.1 7.3 14.7 5.1 3.3 17.1 13.8 6.4 6.7 20.6 2.8 2.1 5.5 33.3 10.8 4.6 19.3 0.0 3.6 9.2 18.0 10.6 16.0 9.0 9.5 21.6 5.1 3.1 10.1 6.6 11.1 0.0 5.3 5.3 29.5 4.0 0.0 21.9 11.7 4.1 4.4 7.7 26.3 8.1 2.9 3.6 10.3 4.1 5.3 3.1 8.5 13.6 3.5 17.2 11.3 7.2 5.4 33.6 5.5 11.7 11.9 19.7 8.6 9.8 17.9 6.1 14.6 12.9 7.3 9.0 5.9 16.5 4.5 FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034821, HPA041444" Approved Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA034821: AB_10669897, HPA041444: AB_2677484" "unprognostic (7.72e-2)" "unprognostic (5.75e-3)" "unprognostic (1.95e-2)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (7.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.29e-2)" "unprognostic (2.21e-3)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.70e-3)" 12.8 11.5 7.3 12.9 8.4 9.8 13.9 8.1 9.9 14.1 8.2 12.5 9.6 12.5 11.1 10.5 10.0 11.5 17.4 7.0 7.7 12.9 18.0 14.5 14.6 8.0 7.6 12.3 9.5 18.5 10.2 13.8 8.0 14.6 13.0 11.0 11.5 12.0 18.7 12.2 11.6 12.3 7.5 14.4 12.5 12.4 7.8 20.2 12.2 16.8 15.6 13.8 11.2 9.9 12.6 13.2 20.1 14.7 22.1 24.6 10.4 16.1 30.7 22.4 30.5 19.6 15.1 18.2 15.5 26.2 23.6 17.2 21.2 20.3 26.8 20.1 13.6 10.8 19.0 13.3 21.9 29.6 17.0 24.0 17.1 21.6 21.1 24.0 30.7 16.6 12.2 19.1 22.3 5.1 18.8 13.8 9.4 13.9 19.8 16.6 29.3 18.4 21.7 14.5 17.9 17.3 21.4 14.2 21.2 17.1 15.0 21.2 20.2 20.4 7.3 10.8 18.2 23.3 25.1 15.3 20.3 16.6 15.8 15.1 6.1 9.1 5.0 8.0 5.5 4.9 4.7 5.0 7.5 3.8 4.8 6.2 11.2 7.7 15.2 3.7 7.4 4.9 7.3 8.4 8.1 9.9 7.0 7.7 8.0 7.6 8.0 7.5 7.8 9.9 10.6 16.0 45.7 25.1 13.8 3.3 5.5 7.4 7.4 10.3 8.5 6.7 18.7 11.5 10.6 11.0 10.4 7.5 13.4 11.3 5.9 8.8 11.2 8.9 9.9 10.8 9.6 7.2 40.2 6.7 6.8 11.8 14.8 10.4 15.8 9.6 11.4 16.9 12.6 13.5 37.4 10.1 6.1 24.9 6.4 2.9 9.0 17.8 3.6 38.4 12.3 5.9 12.3 33.2 44.4 9.9 8.9 18.4 11.0 8.6 9.3 9.3 16.4 9.0 0.0 6.9 7.8 20.6 8.6 9.2 3.8 12.3 12.1 11.2 9.0 8.7 FBXO41 "Fbx41, KIAA1940" ENSG00000163013 "F-box protein 41" Q8TF61 2 73254682-73284478 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.9;Enteroendocrine cells: 12.0;Excitatory neurons: 28.8;Inhibitory neurons: 22.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 21.2;basal ganglia: 31.0;cerebral cortex: 42.3;hippocampal formation: 29.6;white matter: 24.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055246, HPA058386" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA055246: AB_2682758, HPA058386: AB_2683701" "unprognostic (1.15e-3)" "unprognostic (9.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.74e-2)" "unprognostic (5.85e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-1)" "unprognostic (7.97e-3)" "unprognostic (7.55e-2)" "unprognostic (9.13e-3)" "unprognostic (4.35e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-2)" 1.3 3.0 21.2 4.6 31.0 3.3 1.5 7.2 42.3 1.7 0.0 1.8 1.4 1.6 2.3 1.3 1.7 1.7 1.0 29.6 4.6 1.1 0.4 1.5 7.7 4.2 3.8 2.5 3.7 5.5 13.9 0.5 4.6 2.6 1.4 3.1 2.6 2.0 0.1 2.3 5.3 1.2 1.1 9.1 1.8 2.3 5.4 5.5 1.2 0.1 6.9 1.5 1.4 24.8 6.4 3.1 1.0 0.0 0.3 0.2 1.4 1.2 1.0 2.0 2.5 7.2 3.6 46.6 0.2 0.2 4.5 5.1 6.5 4.1 2.0 19.4 0.6 14.5 8.0 3.0 1.5 22.2 10.4 2.5 1.6 0.1 1.6 5.6 0.3 12.7 2.9 7.6 2.1 1.7 7.7 20.4 4.7 2.4 2.7 25.4 11.7 23.2 1.3 2.2 15.7 5.8 8.0 3.3 5.0 0.3 4.5 9.2 0.4 7.0 5.9 6.4 1.2 8.5 3.9 22.1 1.8 23.7 3.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 21.2 31.0 7.2 42.3 29.6 4.6 4.2 3.8 4.6 1.1 5.4 24.8 0.3 0.0 0.6 2.6 5.1 0.3 0.3 1.0 1.2 13.9 1.8 1.4 2.1 1.5 0.3 1.8 0.0 0.0 3.4 0.5 0.0 0.5 0.2 0.3 2.5 0.4 12.0 0.0 28.8 2.5 0.1 2.1 0.0 1.1 2.5 2.1 0.7 0.0 1.9 6.7 22.4 0.4 2.0 4.7 1.1 1.5 0.3 3.2 1.8 7.5 2.6 0.9 2.1 5.5 0.9 1.1 0.3 0.7 3.6 0.8 0.1 0.3 1.1 2.3 0.0 0.3 0.7 1.3 2.4 0.5 0.3 0.0 3.1 5.4 0.8 0.2 FBXO46 "20D7-FC4, Fbx46, FBXO34L" ENSG00000177051 "F-box protein 46" Q6PJ61 19 45710629-45730896 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049390 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Vesicles" Cytosol "HPA049390: AB_2680742" "unprognostic (9.02e-3)" "unprognostic (1.01e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (9.33e-2)" "prognostic favorable (5.44e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.08e-1)" "unprognostic (2.06e-1)" "unprognostic (6.13e-2)" "prognostic favorable (8.11e-4)" "unprognostic (9.77e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (5.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (5.09e-6)" 7.5 7.2 10.6 11.1 11.0 9.2 8.9 9.5 12.6 13.5 18.4 11.7 7.6 13.6 7.5 21.4 10.3 5.1 8.5 8.8 12.2 7.9 10.5 7.4 14.7 8.7 9.6 14.1 9.6 5.8 9.4 6.6 11.5 9.8 7.5 9.9 10.1 5.3 11.4 13.4 11.1 6.3 6.0 14.4 10.8 12.3 9.9 11.1 10.4 5.4 13.9 9.3 13.0 20.9 14.0 21.5 16.2 18.9 4.1 7.3 18.3 7.1 4.0 5.6 6.5 17.8 17.9 24.1 9.5 4.0 7.9 19.9 12.1 9.1 4.2 30.0 25.5 19.6 84.1 9.8 6.2 8.7 24.2 6.1 8.1 9.5 5.9 14.0 8.4 29.4 15.6 28.4 4.6 13.2 20.3 10.2 10.2 13.0 7.3 27.3 9.0 22.6 6.7 16.3 16.1 14.1 11.4 23.7 9.4 15.3 20.1 10.7 9.6 11.8 10.6 6.5 12.0 27.2 41.0 16.1 13.1 12.3 9.8 4.6 1.1 1.2 1.8 0.9 1.2 2.1 1.3 1.3 0.8 3.8 1.2 1.4 3.3 0.6 1.2 1.3 1.4 0.7 10.6 11.0 9.5 12.6 8.8 12.2 8.7 9.6 11.5 6.0 9.9 20.9 4.8 9.6 4.8 6.2 6.5 26.0 10.0 5.7 9.1 3.3 12.7 8.5 5.4 10.0 6.1 7.3 2.1 7.9 3.4 16.3 1.9 6.5 2.9 8.0 5.1 5.2 7.3 5.9 6.5 4.9 19.0 3.6 6.1 9.2 3.8 11.4 4.2 21.1 3.7 11.8 5.5 12.7 0.0 5.7 8.8 3.1 5.6 3.3 5.4 5.6 5.6 4.0 7.2 4.0 6.1 6.9 12.2 1.9 5.5 8.0 6.3 2.2 7.2 3.4 0.0 3.6 4.7 6.5 4.6 13.3 35.8 12.4 5.1 4.9 9.3 11.1 FBXW11 "BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696" ENSG00000072803 "F-box and WD repeat domain containing 11" Q9UKB1 5 171861549-172006873 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072204 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "HPA072204: AB_2686493" "unprognostic (4.04e-3)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (6.87e-2)" "unprognostic (9.43e-2)" "unprognostic (1.53e-1)" "unprognostic (8.14e-3)" "unprognostic (2.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.54e-1)" "unprognostic (3.76e-3)" "unprognostic (1.76e-1)" 19.5 20.4 33.3 13.6 38.2 8.2 17.0 34.7 41.6 19.9 27.4 14.6 12.6 22.9 12.4 24.2 27.0 17.5 36.1 38.0 35.5 23.0 20.7 17.6 16.7 33.3 34.4 25.6 29.1 33.1 14.2 13.9 33.1 19.0 16.0 37.2 13.5 20.3 34.5 13.7 13.2 26.1 34.4 18.1 20.0 14.3 37.7 17.3 21.1 35.6 22.0 19.2 15.8 42.4 35.4 35.6 52.0 45.2 39.9 40.2 26.4 37.1 51.7 45.0 54.9 36.7 23.1 32.5 44.3 46.4 72.0 22.8 37.6 56.3 74.6 42.7 37.3 26.2 35.0 28.5 35.4 29.8 36.0 28.5 38.2 36.8 59.8 48.5 38.6 27.3 16.6 31.7 55.7 26.5 20.7 15.3 19.8 20.8 39.5 30.1 43.7 22.0 34.8 29.2 21.6 37.2 32.9 27.3 70.8 38.7 34.2 31.0 33.8 44.3 22.0 27.4 37.2 31.8 38.9 22.2 31.3 27.8 34.6 25.4 7.3 7.2 5.8 5.1 6.1 8.5 4.8 5.7 7.3 8.4 4.3 5.7 7.1 14.1 5.7 8.6 5.7 6.6 33.3 38.2 34.7 41.6 38.0 35.5 33.3 34.4 33.1 34.4 37.7 42.4 35.4 25.6 21.2 75.4 52.7 19.1 15.6 21.8 32.5 43.5 26.4 22.1 59.1 42.9 20.8 27.6 8.4 8.5 49.8 25.1 43.0 33.7 32.9 42.0 47.9 26.3 28.8 27.4 86.5 36.9 7.8 24.7 38.2 51.0 20.8 25.8 29.3 43.1 12.8 35.3 85.3 21.6 20.3 29.6 25.3 34.3 29.5 26.6 12.4 62.8 24.6 63.6 16.5 75.9 94.4 54.1 14.9 28.6 36.5 30.2 21.5 52.4 17.1 34.3 46.0 28.2 33.5 34.5 16.0 28.7 23.7 12.0 28.8 17.2 15.0 32.9 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCHO2 ENSG00000157107 "FCH and mu domain containing endocytic adaptor 2" Q0JRZ9 5 72956041-73090522 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 19.3;neutrophil: 20.6" "Group enriched" "Detected in many" 9 "granulocytes: 20.6;monocytes: 6.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037685, HPA037686, HPA077850" Enhanced Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Centrosome "Vesicles, Cytosol" "HPA037685: AB_2675610, HPA037686: AB_10673636, HPA077850: AB_2686860" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (6.59e-2)" "unprognostic (2.68e-3)" "unprognostic (4.99e-2)" "unprognostic (6.25e-2)" "unprognostic (1.31e-1)" "unprognostic (5.67e-2)" "unprognostic (6.56e-3)" "unprognostic (1.21e-1)" "prognostic favorable (7.00e-5)" "unprognostic (1.43e-1)" "unprognostic (3.27e-3)" "unprognostic (9.59e-2)" "unprognostic (1.76e-1)" 16.6 9.8 5.1 11.3 6.5 10.7 15.0 9.8 9.1 14.5 11.4 16.3 17.1 16.1 9.0 29.6 11.3 16.9 10.6 5.2 5.0 19.7 17.9 21.8 11.0 6.7 5.6 14.9 9.1 15.3 4.1 21.2 6.4 13.0 17.1 9.1 11.6 12.6 10.4 12.3 18.6 13.4 5.3 17.1 13.6 7.2 8.8 5.2 24.0 12.2 9.2 14.9 16.5 9.5 15.0 11.8 11.3 9.9 15.6 20.5 33.0 12.9 19.0 9.6 15.1 6.0 25.6 3.5 17.6 18.0 17.8 11.1 9.6 22.6 13.0 3.8 11.3 7.3 9.9 7.6 7.8 1.5 7.3 13.8 11.5 12.8 20.6 21.9 22.3 3.5 8.4 6.2 20.2 7.0 0.0 7.3 3.6 3.0 6.1 3.2 10.8 4.4 23.4 20.8 4.5 7.1 17.7 12.6 8.3 15.7 15.1 10.4 23.1 12.5 5.8 13.9 9.3 2.2 4.4 0.7 8.1 1.1 15.8 19.3 3.2 8.8 1.5 4.6 1.0 0.4 0.5 0.6 1.4 0.9 0.2 0.5 20.6 0.9 6.6 0.5 0.4 0.8 5.1 6.5 9.8 9.1 5.2 5.0 6.7 5.6 6.4 5.3 8.8 9.5 51.8 57.7 44.3 34.9 3.8 10.5 15.6 12.0 12.5 11.1 16.5 12.3 15.1 14.3 23.1 35.0 4.2 14.2 7.0 25.6 13.7 16.0 2.4 24.3 17.0 36.8 14.9 12.6 78.2 17.5 8.9 22.8 17.3 38.3 18.3 9.5 52.1 11.0 19.8 11.8 51.5 14.8 8.2 81.0 13.0 2.8 13.4 45.8 16.0 71.2 12.9 15.4 3.1 62.4 59.1 30.7 29.4 13.9 3.5 22.5 21.0 21.8 21.5 8.9 26.3 25.1 21.3 16.9 14.3 15.0 15.3 13.7 4.4 9.1 14.0 30.2 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FCMR "FAIM3, TOSO" ENSG00000162894 "Fc fragment of IgM receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 65.5;lymphoid tissue: 180.6" "Cell type enhanced" "Detected in many" "B-cells: 262.3;dendritic cells: 43.5;NK-cells: 108.1;T-cells: 74.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "RPMI-8226: 171.4;U-266/70: 73.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003910 Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 5500000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" 4.9 1.5 0.3 74.8 0.3 12.6 2.4 0.3 0.8 1.5 0.4 8.0 6.1 2.4 2.6 3.0 1.9 11.3 2.6 0.1 0.4 2.3 5.9 6.0 152.1 0.4 0.1 0.8 1.1 0.5 1.0 1.8 0.2 3.4 9.9 0.2 3.5 1.2 3.6 0.4 65.5 2.3 0.0 115.0 14.2 0.5 0.5 77.2 3.3 1.4 180.6 19.1 1.6 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.3 0.3 0.0 0.0 11.6 0.0 0.4 0.7 0.3 0.0 0.6 0.5 0.0 0.2 0.2 0.9 0.0 1.6 0.1 0.0 0.1 0.7 0.3 1.2 0.0 0.0 7.0 0.2 23.5 0.0 0.2 3.5 0.3 0.1 0.0 0.2 4.9 0.6 171.4 0.1 0.3 0.1 0.0 2.8 0.6 13.0 0.0 0.3 0.0 0.5 0.0 0.5 0.2 0.1 73.8 5.9 23.2 0.8 0.1 0.6 7.9 2.8 3.6 209.3 4.3 276.9 882.3 280.1 266.3 3.2 1057.5 483.2 336.0 56.0 218.8 4.3 13.7 687.7 416.6 0.3 0.3 0.3 0.8 0.1 0.4 0.4 0.1 0.2 0.0 0.5 0.6 1.3 0.0 3.9 0.0 262.3 0.0 4.9 0.0 1.2 0.0 3.5 3.0 3.6 5.7 1.3 0.0 0.0 0.1 43.5 0.9 0.0 1.7 0.2 0.8 0.7 1.7 0.0 8.4 0.0 2.9 0.1 3.4 4.1 0.9 0.0 0.6 4.6 1.4 4.4 0.0 0.0 0.6 0.0 5.7 0.0 0.4 0.3 8.1 0.0 0.0 3.6 0.0 108.1 0.0 0.0 1.2 0.3 0.0 30.5 2.9 0.1 1.0 0.7 0.0 0.0 0.2 2.9 0.1 2.3 1.7 0.0 0.0 74.9 0.0 1.9 6.8 FEM1A ENSG00000141965 "Fem-1 homolog A" Q9BSK4 19 4791734-4801273 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "skeletal muscle: 273.6;tongue: 121.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016565, HPA063622" Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus" Cytosol "HPA016565: AB_1848489, HPA063622: AB_2685063" "unprognostic (4.62e-2)" "unprognostic (1.96e-1)" "unprognostic (1.66e-1)" "unprognostic (6.75e-2)" "unprognostic (3.60e-1)" "unprognostic (2.42e-3)" "unprognostic (2.04e-1)" "unprognostic (6.74e-2)" "unprognostic (1.25e-2)" "unprognostic (9.21e-2)" "unprognostic (2.28e-3)" "unprognostic (6.25e-2)" "unprognostic (6.18e-5)" "unprognostic (3.72e-3)" "unprognostic (1.25e-1)" "unprognostic (1.91e-1)" "unprognostic (4.70e-2)" 4.3 3.7 8.0 4.0 7.8 7.5 4.4 8.1 8.0 3.2 6.8 3.8 3.7 3.0 3.6 8.4 3.4 2.7 17.8 8.2 6.1 3.8 4.4 4.2 4.7 7.9 7.5 3.5 8.5 9.6 0.9 4.2 7.3 4.9 3.3 3.0 5.9 3.3 273.6 8.5 3.3 3.9 7.1 4.3 3.9 2.4 7.8 4.8 3.5 121.2 4.6 4.1 1.0 8.5 9.2 6.2 5.7 12.4 6.2 3.6 8.3 5.4 4.4 8.5 6.0 9.7 4.1 10.4 5.4 6.7 4.6 9.3 10.1 8.9 5.5 12.4 11.6 10.1 4.9 7.4 9.4 17.0 12.4 5.3 13.6 6.6 9.4 4.0 6.2 13.9 15.1 19.3 5.9 9.3 14.3 6.2 17.7 5.7 15.0 13.1 7.4 11.0 7.7 11.6 18.5 13.1 7.1 13.2 10.4 4.3 10.2 14.5 8.7 7.7 5.6 12.1 14.4 22.3 20.0 8.8 7.9 12.1 11.1 4.7 2.8 2.8 2.5 3.2 2.1 1.9 2.0 2.3 2.6 2.5 1.7 2.0 2.4 2.6 3.0 2.6 1.5 1.8 8.0 7.8 8.1 8.0 8.2 6.1 7.9 7.5 7.3 7.1 7.8 8.5 7.9 25.6 32.8 1.6 16.6 20.1 14.9 7.7 12.5 16.8 20.8 16.4 6.5 18.6 15.5 1.8 16.7 21.2 16.1 16.7 13.7 10.3 5.3 8.7 11.6 12.3 13.1 28.6 2.7 11.8 13.8 9.2 6.1 19.1 22.8 7.5 15.4 18.7 12.3 11.8 3.2 15.5 4.1 15.4 8.7 3.5 9.0 13.1 3.6 2.8 17.2 12.1 32.0 2.5 2.3 12.4 9.4 8.2 9.9 15.5 10.9 10.1 11.3 19.8 6.6 27.1 9.3 12.7 6.2 18.3 29.5 27.1 14.3 16.8 18.0 17.7 FERMT2 "KIND2, mig-2, PLEKHC1, UNC112B" ENSG00000073712 "Fermitin family member 2" Q96AC1 14 52857268-52952435 "Predicted intracellular proteins" "Cell adhesion, Cell shape, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040505, HPA072965" Uncertain Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 230000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA040505: AB_10673300, HPA072965: " "unprognostic (4.38e-2)" "unprognostic (4.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.42e-2)" "unprognostic (2.51e-2)" "unprognostic (4.89e-3)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.58e-1)" "unprognostic (1.99e-1)" "unprognostic (3.87e-2)" "unprognostic (3.96e-3)" "unprognostic (7.69e-2)" "unprognostic (3.14e-1)" "unprognostic (1.73e-3)" 148.4 21.2 28.7 38.8 31.6 0.5 57.6 29.0 37.3 44.7 18.0 104.3 13.1 105.1 26.3 46.8 55.7 65.7 66.9 31.0 27.4 55.4 108.3 47.9 15.3 35.7 29.1 43.6 20.6 18.4 13.1 116.5 33.5 69.1 33.3 29.5 22.6 117.9 48.8 13.4 29.3 155.6 30.6 37.6 46.4 15.5 27.6 6.9 35.9 69.6 6.6 77.7 29.1 38.1 22.8 18.9 101.6 46.8 163.7 133.7 84.6 148.4 95.2 172.3 107.9 34.1 17.6 0.1 49.4 153.1 33.8 9.6 80.1 11.1 128.3 0.2 22.6 31.9 83.1 40.3 209.6 0.4 12.6 129.4 23.5 95.3 125.4 78.5 91.2 16.8 0.6 153.4 131.7 28.0 7.7 0.5 64.3 0.2 51.3 3.9 103.8 0.4 60.9 20.6 6.2 130.5 157.8 35.0 37.7 103.3 30.1 1.1 115.2 134.5 92.4 108.2 56.0 22.6 29.4 0.6 30.9 0.2 33.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 31.6 29.0 37.3 31.0 27.4 35.7 29.1 33.5 30.6 27.6 38.1 152.7 76.9 42.0 116.5 1.0 18.6 150.6 15.5 13.6 39.5 33.8 41.4 65.8 24.3 25.6 40.5 37.5 74.8 2.3 0.2 31.3 48.5 68.2 20.1 141.7 110.4 0.0 2.7 13.7 33.2 178.1 103.9 3.6 40.2 58.3 31.6 110.3 82.3 10.4 15.2 16.1 0.5 4.1 8.9 19.5 27.9 74.9 4.4 46.2 29.0 4.8 52.3 1.0 41.2 92.0 27.6 0.1 174.9 4.5 40.0 0.0 44.7 10.1 56.0 151.2 83.4 174.1 4.1 16.2 2.2 8.1 102.6 7.9 12.3 0.4 37.0 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: AB_10672235" "unprognostic (1.42e-1)" "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-2)" "unprognostic (1.94e-3)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (7.82e-3)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" 53.0 39.1 48.2 21.0 51.6 16.5 35.9 48.2 68.6 26.9 42.8 34.5 22.1 33.1 18.9 31.7 23.8 23.6 46.7 49.2 48.4 33.6 29.4 27.1 24.3 49.5 46.3 27.6 10.8 20.3 14.2 46.8 48.2 23.5 27.9 26.5 17.1 32.5 108.1 17.0 28.5 41.1 50.1 30.3 21.9 20.8 49.6 18.2 23.9 78.5 19.5 29.1 24.3 56.3 64.9 37.1 49.4 22.3 91.3 122.1 39.5 157.1 76.5 90.7 56.0 24.6 21.5 39.1 94.7 199.2 41.0 25.1 42.4 54.3 98.5 9.3 24.7 31.7 12.2 43.5 44.4 32.9 8.5 119.9 44.2 57.8 69.6 61.2 131.0 9.5 35.4 12.0 170.2 22.7 19.6 27.5 27.1 33.9 57.8 16.9 44.3 14.0 72.9 57.6 1.9 45.7 38.7 31.9 37.8 51.7 11.3 39.1 161.2 59.7 32.9 33.4 92.9 9.8 11.5 26.6 58.9 22.4 84.8 2.5 3.5 5.1 1.7 3.4 1.0 1.6 1.3 1.0 3.5 1.0 1.5 0.7 4.2 3.2 2.3 15.6 1.4 0.8 48.2 51.6 48.2 68.6 49.2 48.4 49.5 46.3 48.2 50.1 49.6 56.3 109.4 54.5 37.5 25.8 23.7 31.4 94.7 45.5 41.5 52.5 31.7 33.1 43.1 17.2 70.2 58.8 45.9 96.4 61.1 57.6 56.7 80.3 5.6 38.4 44.7 100.9 24.0 15.3 45.4 30.6 87.6 50.7 27.0 64.3 24.1 66.0 97.5 37.2 93.7 21.9 22.9 28.8 38.7 88.1 65.4 10.7 54.3 64.6 56.9 45.0 56.0 97.1 35.0 23.1 50.5 74.4 41.4 66.2 17.9 99.1 65.6 45.1 35.9 36.3 59.2 64.0 51.2 12.1 34.9 24.0 32.1 180.1 24.2 47.2 37.7 140.6 FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266599-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.7;gallbladder: 3.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 9.4;Microglial cells: 1.9;Proximal tubular cells: 4.1" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 11.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.1;BJ hTERT+: 120.0;fHDF/TERT166: 88.0;HBF TERT88: 88.0;LHCN-M2: 81.1;U-138 MG: 109.5;U-251 MG: 55.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB010313, HPA042442" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010313: AB_2102677, HPA042442: AB_2678001" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (8.49e-4)" "unprognostic (1.10e-1)" "unprognostic (2.91e-1)" "unprognostic (2.80e-3)" "unprognostic (6.87e-4)" "unprognostic (2.53e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.33e-16)" "unprognostic (3.02e-3)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" 0.0 0.0 0.2 0.6 0.0 0.1 0.0 11.7 1.2 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.0 3.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 2.7 0.2 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 1.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.1 6.1 21.8 0.0 64.1 120.0 16.5 12.2 0.0 0.1 0.0 0.0 88.0 1.2 0.1 0.1 22.5 88.0 0.0 1.1 0.2 0.1 0.0 1.7 0.6 0.0 6.3 0.0 48.6 23.0 27.9 5.7 0.0 0.0 0.2 81.1 0.0 0.1 0.3 0.1 0.0 2.1 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.8 0.0 0.0 0.2 20.9 109.5 4.6 5.4 55.0 0.0 0.0 0.1 6.3 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.7 1.2 0.6 0.0 2.7 0.2 3.0 0.0 0.5 0.5 0.0 0.0 1.1 0.3 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.6 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FIGN ENSG00000182263 "Fidgetin, microtubule severing factor" Q5HY92 2 163593396-163736012 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 161.3;Inhibitory neurons: 82.9;Oligodendrocyte precursor cells: 309.6;Oligodendrocytes: 129.4;Sertoli cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 3.3" "Lineage enriched" "Detected in single" 34 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "AF22: 18.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034987, HPA057919" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Cell Junctions" "HPA034987: AB_10669681, HPA057919: " "unprognostic (3.93e-2)" "unprognostic (8.30e-3)" "unprognostic (1.48e-1)" "unprognostic (7.68e-5)" "unprognostic (3.45e-2)" "unprognostic (8.98e-4)" "unprognostic (5.23e-3)" "unprognostic (7.65e-3)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (2.07e-2)" "unprognostic (3.24e-2)" "unprognostic (3.85e-3)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (4.10e-2)" "unprognostic (3.78e-2)" 3.1 2.0 3.9 0.4 5.0 0.8 2.0 2.3 4.4 2.4 0.0 2.6 0.4 1.1 1.2 0.6 1.9 1.1 3.3 2.5 5.4 1.9 3.2 1.4 0.6 3.0 4.2 4.6 2.9 0.4 2.6 1.1 3.9 1.6 0.7 1.4 2.6 2.7 1.0 1.0 1.4 0.9 1.8 3.0 1.8 1.1 4.6 0.2 1.1 1.7 0.2 1.7 2.4 5.1 6.4 2.3 18.6 0.0 0.0 0.0 6.8 2.4 1.6 1.7 3.2 0.0 2.2 0.0 6.6 2.6 3.4 0.9 6.2 2.6 1.3 0.0 4.6 0.0 4.7 4.6 1.5 0.0 0.0 0.8 2.2 3.3 9.0 2.6 4.0 0.0 0.0 0.0 5.1 1.6 0.0 0.0 7.9 0.4 2.9 0.0 6.3 0.0 4.2 2.1 2.9 2.5 0.0 1.8 1.7 10.3 2.0 0.0 0.4 7.6 6.8 0.0 5.1 1.1 0.0 0.0 2.3 0.0 4.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.0 2.3 4.4 2.5 5.4 3.0 4.2 3.9 1.8 4.6 5.1 2.9 6.4 7.3 161.3 0.7 1.9 0.1 2.8 1.8 24.4 5.7 2.7 19.4 20.0 3.0 12.9 0.0 21.2 0.2 0.1 1.9 3.7 3.8 0.7 0.7 2.1 0.0 0.0 53.4 1.5 7.4 11.6 4.1 1.6 0.0 23.6 7.9 13.5 1.4 6.7 82.9 0.0 4.1 0.0 1.6 6.4 51.9 0.6 17.8 28.1 0.0 4.3 0.0 309.6 129.4 1.1 0.0 34.3 0.0 1.8 0.0 8.1 4.0 2.1 72.3 16.6 17.8 1.1 1.2 1.0 0.4 16.8 0.2 7.0 0.0 0.0 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 6.5 5.1 3.4 7.0 3.5 4.3 6.4 5.4 3.6 9.9 3.1 4.7 3.0 8.5 10.0 4.7 4.3 6.0 6.8 3.2 3.2 3.1 3.2 4.1 3.1 3.3 3.1 5.4 5.8 6.2 7.7 7.9 3.0 6.8 4.8 7.2 4.3 7.5 2.1 4.7 2.9 13.9 3.0 2.7 4.0 2.2 3.5 1.8 3.3 3.2 3.2 8.9 3.8 3.5 7.0 5.2 14.4 33.6 36.8 46.8 6.5 34.9 32.7 12.0 23.3 4.4 4.3 2.4 16.0 31.0 14.7 14.8 8.1 12.8 23.9 1.3 11.6 5.6 9.2 13.1 18.6 4.0 9.3 29.4 13.1 20.9 24.6 28.2 27.0 3.6 9.2 5.0 21.8 2.9 2.1 4.9 7.5 7.7 9.2 0.1 9.6 8.2 11.8 6.1 3.8 12.5 12.2 27.5 8.8 17.0 6.2 5.3 21.7 12.6 14.6 21.8 14.0 7.6 8.3 4.2 18.0 3.8 40.2 0.5 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.4 0.2 0.0 0.6 0.2 0.1 3.4 3.5 5.4 3.6 3.2 3.2 3.3 3.1 3.0 3.0 3.5 3.5 13.5 19.2 16.0 7.2 7.9 27.4 22.0 15.8 35.9 16.3 13.3 13.0 15.7 5.7 11.7 18.4 27.1 11.6 9.4 5.3 1.9 7.4 0.4 30.4 44.3 12.9 1.2 6.5 19.4 3.7 27.3 40.0 15.3 40.0 2.5 9.1 8.6 6.5 6.0 15.2 12.7 9.7 8.2 2.5 11.2 0.4 13.1 5.7 10.6 10.3 3.6 26.5 2.1 11.6 16.6 5.7 19.0 20.7 43.8 17.8 3.3 2.7 6.0 21.4 6.6 13.8 20.4 1.4 3.4 27.5 18.3 15.7 6.0 20.8 6.1 28.0 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 719.1;Late spermatids: 1236.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 93.4;neutrophil: 78.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 10000 "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 206.9 161.5 426.8 79.8 423.7 272.9 197.3 359.7 645.5 235.3 332.7 311.1 85.5 188.6 59.0 238.3 198.1 85.5 244.3 427.4 395.7 194.8 233.7 187.6 97.9 427.6 405.1 263.6 167.2 109.1 312.3 91.2 406.1 249.4 33.6 51.4 200.0 115.3 202.7 185.9 159.2 62.5 381.7 193.6 189.3 378.4 423.4 86.2 205.9 105.5 52.7 228.3 222.4 437.8 196.3 139.0 106.0 201.7 106.2 165.6 266.8 155.0 163.1 116.5 160.2 133.3 259.1 111.6 245.0 191.7 77.7 104.4 65.0 216.5 31.4 136.6 316.5 105.3 175.4 162.3 183.3 105.5 220.6 217.3 204.8 104.0 65.4 216.1 121.9 213.2 222.4 254.8 102.1 329.1 190.4 313.1 216.3 174.6 200.2 197.8 88.4 387.3 154.9 126.6 117.1 213.2 108.8 87.7 197.5 77.8 104.5 299.4 143.2 143.2 130.3 282.1 120.0 194.6 118.2 130.8 321.5 166.7 130.8 18.1 14.7 93.4 14.2 15.5 13.3 10.2 14.6 16.3 11.1 9.8 11.1 12.6 78.0 8.8 19.0 11.3 15.8 30.1 426.8 423.7 359.7 645.5 427.4 395.7 427.6 405.1 406.1 381.7 423.4 437.8 115.9 9.6 1.1 35.3 115.1 95.3 164.1 118.4 68.3 64.8 110.9 107.4 2.0 115.8 58.0 101.2 14.6 246.4 107.0 287.7 248.4 178.4 412.3 65.6 59.2 92.3 205.9 719.1 32.0 126.9 234.8 126.5 80.5 64.6 52.8 125.0 99.6 66.4 237.3 99.3 33.2 156.8 126.1 184.1 145.0 1236.4 203.8 152.1 202.7 8.4 221.9 149.0 183.4 12.5 32.8 166.9 283.4 165.5 127.2 139.4 339.3 290.4 51.9 56.4 98.6 95.7 129.9 193.5 212.4 96.5 117.9 312.9 145.0 121.7 158.3 158.0 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: AB_2678324, HPA060454: AB_2684281" "unprognostic (4.44e-2)" "unprognostic (5.20e-2)" "unprognostic (2.19e-2)" "unprognostic (8.37e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-2)" "unprognostic (4.59e-3)" "prognostic favorable (8.98e-4)" "unprognostic (3.53e-1)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.53e-2)" 10.5 9.1 8.5 8.1 8.2 8.8 9.9 3.7 11.5 11.4 4.5 13.3 4.8 15.2 5.0 8.8 12.6 6.0 15.8 8.5 10.4 12.0 11.9 10.4 7.4 10.1 7.3 12.7 11.1 7.5 16.8 10.1 8.8 13.5 4.3 5.7 11.1 7.4 19.6 7.2 10.5 5.8 6.1 14.7 10.9 9.3 9.4 5.6 13.6 9.8 4.9 13.0 10.5 8.7 12.7 26.5 17.8 12.5 15.4 16.9 15.8 31.7 21.0 12.6 19.9 17.0 21.4 11.7 17.0 18.2 20.9 13.0 6.6 14.8 11.5 21.9 22.2 11.7 14.4 10.7 13.3 9.3 19.8 19.4 12.5 15.6 15.2 14.6 16.7 6.0 12.2 11.0 12.7 5.8 6.8 22.8 17.2 7.8 6.5 18.3 11.1 4.0 8.0 26.4 12.0 23.1 15.8 7.6 10.6 11.7 8.9 7.3 16.8 18.4 19.8 6.7 25.7 11.6 15.4 11.0 15.0 7.5 25.6 1.3 1.8 0.8 1.5 1.0 0.9 1.7 1.1 1.7 1.1 2.4 1.2 1.6 2.2 2.0 1.1 1.9 0.6 1.2 8.5 8.2 3.7 11.5 8.5 10.4 10.1 7.3 8.8 6.1 9.4 8.7 4.7 9.6 7.4 6.8 3.9 0.8 4.8 3.0 1.2 9.8 5.3 5.2 15.5 4.3 5.6 5.5 6.2 9.6 9.1 4.5 5.9 4.2 12.0 7.9 7.3 6.0 7.8 7.8 6.8 2.4 5.9 6.6 3.6 5.1 1.3 6.7 11.4 16.6 7.6 3.3 8.2 4.2 2.0 10.0 1.2 13.2 5.6 4.3 5.4 3.7 6.1 7.8 2.1 8.0 6.2 4.1 4.7 4.1 3.6 4.3 4.2 8.2 9.7 11.0 6.6 7.2 7.0 12.2 4.0 2.4 1.6 18.7 4.3 4.5 4.0 4.3 FLII "FLI, Fli1, FLIL, MGC39265" ENSG00000177731 "FLII actin remodeling protein" Q13045 17 18244815-18258738 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.4" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 198.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007084, HPA008903, CAB016132" Enhanced Enhanced "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Centriolar satellite, Cytosol" "CAB016132: AB_627613, HPA007084: AB_1848638, HPA008903: AB_1848640" "unprognostic (8.09e-2)" "unprognostic (1.09e-2)" "unprognostic (6.89e-2)" "unprognostic (2.53e-2)" "unprognostic (4.22e-2)" "unprognostic (4.78e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-3)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" 57.7 50.0 9.8 22.9 11.5 26.4 55.0 12.6 11.1 50.2 13.4 56.2 19.5 49.6 7.3 65.7 41.3 13.7 75.1 9.9 11.5 42.2 30.7 53.3 20.0 15.4 13.0 39.1 57.6 16.9 39.0 17.0 15.4 41.5 12.9 4.6 63.6 17.4 245.4 46.9 50.8 18.9 12.1 58.0 45.6 35.3 14.2 17.4 44.1 73.1 15.8 61.3 50.3 13.6 198.0 73.5 18.4 30.0 44.2 38.9 29.4 53.7 64.1 59.0 36.4 93.5 45.2 39.7 56.3 61.1 33.7 89.0 26.2 90.1 34.4 32.6 42.6 20.5 54.9 36.9 50.0 23.6 44.3 36.4 53.3 47.9 71.8 36.2 58.0 35.3 18.0 15.0 34.9 61.3 34.9 20.5 20.5 85.1 37.8 34.3 87.2 48.7 43.5 58.4 7.2 10.9 63.1 51.0 28.7 117.2 90.8 17.8 73.3 53.6 54.4 104.0 64.4 15.9 12.5 11.5 50.8 23.5 28.7 10.0 27.5 25.6 12.8 39.3 12.5 9.3 9.9 13.0 30.2 6.0 7.3 8.2 22.6 10.5 51.1 8.6 12.7 24.2 9.8 11.5 12.6 11.1 9.9 11.5 15.4 13.0 15.4 12.1 14.2 13.6 44.9 60.9 36.9 12.7 23.3 22.7 24.9 35.1 26.7 15.4 29.6 23.9 37.4 22.8 47.3 25.8 18.8 25.9 24.8 62.8 15.6 53.5 45.2 37.5 27.9 38.7 23.9 21.7 7.2 56.9 28.7 28.4 42.3 56.6 46.9 28.8 27.5 19.4 48.9 26.9 7.4 26.0 24.4 46.2 39.7 9.2 32.3 52.2 16.0 14.0 55.7 11.4 12.3 3.5 14.2 134.4 49.8 35.0 31.8 40.7 48.8 21.3 50.3 12.7 32.9 28.0 30.7 40.0 20.0 33.8 19.6 25.4 32.1 33.3 40.9 38.6 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 156.5;Basal prostatic cells: 168.3;Club cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 27.5;hTCEpi: 51.3;RPTEC TERT1: 17.3;WM-115: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA 1100000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" 5.0 3.7 2.3 0.8 3.0 0.0 2.3 6.4 5.3 3.2 0.9 1.6 11.8 2.3 3.1 1.6 2.4 5.0 0.6 5.3 1.3 23.2 7.0 17.7 0.1 0.0 1.3 10.6 1.2 8.2 1.0 1.8 0.8 8.2 0.8 1.6 1.2 14.0 2.0 6.3 2.3 1.4 0.6 0.7 9.7 1.2 2.3 7.3 5.2 0.7 0.3 7.9 2.1 1.8 0.0 12.2 27.5 0.0 0.0 0.0 0.0 2.7 0.8 0.1 0.0 15.3 5.6 0.0 0.9 0.6 0.0 8.0 0.0 8.3 0.1 0.0 1.8 0.0 0.4 0.3 2.4 0.0 0.0 4.6 51.3 0.0 9.7 0.0 0.1 0.2 0.0 0.2 5.3 0.4 3.7 0.0 8.9 6.2 0.1 0.1 0.2 0.0 17.3 3.6 0.5 5.7 0.0 0.0 9.2 15.5 0.5 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.0 0.0 0.2 0.0 62.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 6.4 5.3 5.3 1.3 0.0 1.3 0.8 0.6 2.3 1.8 0.3 218.0 156.5 2.3 0.5 8.7 168.3 26.1 55.8 23.9 4.4 6.5 1.2 24.3 73.1 22.0 6.2 0.5 0.0 2.2 13.7 23.6 0.2 0.7 1.7 1.9 11.3 0.0 27.2 14.9 0.0 8.7 37.8 0.7 5.1 5.0 2.9 8.5 0.2 6.7 39.3 2.5 2.0 0.3 0.7 0.5 3.7 1.3 5.4 1.9 1.6 0.6 0.0 26.2 3.9 10.0 3.0 0.4 0.1 24.9 3.5 49.2 13.4 3.3 0.0 25.0 1.8 0.0 0.1 5.9 16.6 0.0 0.8 1.4 1.5 18.3 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FLYWCH1 DKFZp761A132 ENSG00000059122 "FLYWCH-type zinc finger 1" Q4VC44 16 2911931-2951208 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040753, HPA041001" Approved Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA040753: AB_10794880, HPA041001: AB_10794259" "unprognostic (2.26e-1)" "unprognostic (1.66e-2)" "unprognostic (2.93e-1)" "unprognostic (2.06e-3)" "unprognostic (1.71e-1)" "unprognostic (2.68e-2)" "unprognostic (3.51e-2)" "unprognostic (1.92e-1)" "unprognostic (7.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-3)" "unprognostic (6.61e-2)" "unprognostic (1.61e-1)" "unprognostic (3.84e-2)" "unprognostic (7.33e-2)" "unprognostic (2.19e-3)" "unprognostic (7.91e-2)" 16.0 14.6 22.6 11.7 22.4 12.5 14.2 22.6 28.7 18.6 15.9 19.3 12.9 17.7 4.8 12.8 17.0 13.0 19.0 18.9 20.8 12.8 8.3 14.0 11.3 33.2 23.3 20.6 10.7 14.7 16.4 8.2 30.0 17.2 3.7 13.3 13.7 12.5 32.8 20.4 14.4 7.6 19.2 18.7 13.4 4.0 27.3 9.1 15.5 10.7 6.2 21.8 16.2 23.7 10.0 34.8 7.8 23.2 12.4 12.5 23.6 18.2 14.1 9.0 9.2 5.8 31.8 24.4 47.3 14.0 14.7 20.5 6.5 12.2 1.8 40.8 19.6 8.2 30.9 19.5 27.7 10.9 27.3 11.2 37.9 19.1 13.8 16.7 12.9 16.0 18.6 25.0 7.0 23.8 25.1 13.3 12.7 7.5 23.6 43.5 11.6 44.0 10.6 6.7 16.7 15.5 19.1 20.6 24.1 4.3 16.1 19.6 24.4 15.0 13.6 29.4 12.4 37.1 34.5 22.7 16.4 17.8 17.9 1.2 0.8 0.3 1.3 0.4 2.3 0.9 2.1 2.7 0.8 2.6 1.7 1.5 0.1 0.5 0.4 0.5 1.1 1.1 22.6 22.4 22.6 28.7 18.9 20.8 33.2 23.3 30.0 19.2 27.3 23.7 16.7 0.0 4.2 34.3 10.4 12.4 9.3 9.2 23.3 42.1 8.6 11.3 12.3 8.6 5.1 22.0 35.5 21.2 14.3 6.5 1.9 6.1 0.4 6.0 7.7 13.4 2.4 6.5 26.9 6.5 8.5 13.9 12.2 8.9 0.0 48.3 11.0 6.8 8.5 33.7 29.0 4.9 4.1 9.9 5.1 1.2 11.1 8.9 8.8 13.1 7.9 18.8 9.2 18.6 25.6 7.1 2.9 14.3 10.4 5.3 8.9 6.3 8.3 39.3 0.0 16.6 20.9 0.9 3.2 13.1 13.9 8.8 11.9 5.3 7.4 5.6 FMNL2 "FHOD2, KIAA1902" ENSG00000157827 "Formin like 2" Q96PY5 2 152335174-152649826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 223.5" "Cell type enhanced" "Detected in many" "Astrocytes: 668.0;Excitatory neurons: 574.9;Inhibitory neurons: 321.9;Oligodendrocyte precursor cells: 371.0;Oligodendrocytes: 2442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 5 "monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 191.4;hTERT-HME1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005464 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA005464: AB_1848965" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (8.75e-3)" "unprognostic (3.06e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.54e-1)" "unprognostic (4.66e-2)" "unprognostic (5.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-1)" "unprognostic (3.73e-2)" "unprognostic (1.58e-1)" 26.4 25.2 88.9 11.1 152.3 0.7 20.8 135.2 119.3 18.1 73.6 15.2 8.9 20.7 14.9 8.5 15.3 16.8 12.0 92.9 102.6 22.2 8.1 32.2 14.2 172.3 136.3 54.0 18.1 23.1 28.4 58.2 165.5 15.2 12.3 10.6 32.1 11.7 24.1 11.3 11.6 16.3 121.6 19.8 17.3 9.0 128.5 14.8 33.1 19.3 8.4 19.3 18.3 223.5 14.5 15.1 45.9 25.5 54.5 58.3 191.4 14.4 29.4 24.9 34.8 16.3 0.9 0.3 29.8 12.6 53.7 16.2 22.4 45.8 39.6 0.1 23.4 0.2 10.0 70.2 15.7 4.0 0.8 38.4 27.8 48.2 123.5 48.3 44.7 6.6 0.6 0.3 13.9 4.0 0.8 4.5 29.5 12.4 30.0 25.9 9.9 20.9 72.9 9.9 46.6 38.0 12.2 4.5 51.4 38.7 1.1 1.5 49.9 37.4 1.0 12.7 25.0 1.3 0.5 0.1 34.7 3.3 77.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 88.9 152.3 135.2 119.3 92.9 102.6 172.3 136.3 165.5 121.6 128.5 223.5 21.5 25.6 25.9 668.0 2.7 26.4 23.0 14.0 19.4 23.8 11.4 10.0 3.8 1.5 16.4 11.0 0.0 36.1 4.5 2.6 13.7 20.4 24.5 14.1 10.8 29.1 8.3 0.4 574.9 6.9 17.8 36.2 8.2 27.0 1.3 36.0 20.0 1.3 40.6 0.0 321.9 3.3 10.2 64.8 53.0 10.5 35.1 31.5 7.2 245.4 4.4 3.9 1.0 371.0 2442.0 10.0 2.1 41.3 5.6 33.5 0.7 8.9 8.5 2.0 6.6 18.7 13.2 6.7 8.0 6.3 16.9 27.0 2.1 13.0 6.1 13.2 FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 35.8;Cone photoreceptor cells: 39.6;dendritic cells: 48.6;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" 12.2 5.7 13.7 20.5 13.2 5.2 10.6 13.0 11.2 9.6 3.0 8.0 5.7 11.2 19.2 4.5 6.9 11.1 12.6 11.0 12.6 9.3 2.7 17.4 23.5 21.7 14.6 16.1 3.2 3.6 4.1 14.0 18.2 6.0 5.6 2.7 4.6 4.4 5.6 4.4 10.2 11.5 17.7 13.4 6.6 10.1 20.4 20.1 13.4 6.7 28.3 8.6 6.3 20.4 8.6 2.5 18.4 6.1 5.0 20.1 0.2 10.4 21.0 13.8 12.1 9.7 2.3 18.2 19.5 12.4 15.2 0.4 9.5 4.3 12.6 16.2 3.6 20.1 2.9 0.5 8.8 4.0 25.1 12.7 0.7 21.7 9.1 41.2 37.1 9.0 4.6 13.0 20.5 6.3 16.6 6.0 6.0 0.9 5.5 7.9 23.0 2.8 13.1 1.3 3.0 8.6 6.0 0.8 11.8 9.3 1.5 5.9 47.2 34.2 11.8 0.6 18.2 6.7 0.4 9.8 21.3 12.4 14.7 3.0 0.1 0.8 0.8 0.4 0.4 0.2 0.3 0.5 0.2 1.1 0.4 0.5 0.0 0.6 0.3 5.1 0.1 0.5 13.7 13.2 13.0 11.2 11.0 12.6 21.7 14.6 18.2 17.7 20.4 20.4 35.8 3.2 3.4 6.8 17.5 1.7 0.7 0.4 2.2 11.3 1.3 2.3 3.3 0.0 1.4 1.8 39.6 2.1 48.6 0.1 0.0 0.3 2.0 0.7 2.6 29.7 0.0 1.7 16.0 0.6 0.8 7.1 1.5 2.0 27.8 5.4 15.7 0.8 11.1 3.3 6.5 0.8 0.0 6.9 9.0 4.6 3.7 17.7 5.4 119.0 22.9 0.5 16.5 27.6 5.5 0.8 0.1 6.4 1.8 0.8 0.0 0.2 0.2 2.0 13.1 15.5 10.3 5.9 7.5 0.4 1.4 2.5 13.6 2.6 0.1 0.4 FNDC11 "C20orf195, MGC5356" ENSG00000125531 "Fibronectin type III domain containing 11" Q9BVV2 20 63547891-63556695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "testis: 108.0" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Collecting duct cells: 1.8;Endometrial ciliated cells: 5.1;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 3.3" "Lineage enriched" "Detected in single" 7 "B-cells: 3.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.2;EFO-21: 2.6;HaCaT: 1.5;OE19: 1.8;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA041341 Approved Nucleoplasm,Vesicles,Aggresome NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Vesicles" Aggresome "HPA041341: AB_10794991" "unprognostic (2.01e-1)" "unprognostic (6.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (2.36e-1)" "unprognostic (9.99e-3)" "unprognostic (7.94e-2)" "unprognostic (8.30e-4)" "unprognostic (3.68e-1)" "unprognostic (8.33e-2)" "unprognostic (3.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (3.75e-1)" "unprognostic (6.81e-2)" 0.4 0.1 0.2 0.3 0.1 0.5 0.6 0.1 0.3 0.8 0.3 0.3 0.1 0.4 2.3 0.2 1.2 0.3 0.2 0.1 1.1 1.2 0.1 0.9 0.6 0.5 0.5 0.4 0.1 0.0 0.9 0.1 0.3 0.6 0.0 0.0 0.4 0.1 0.1 0.4 0.6 0.0 0.4 1.0 0.4 108.0 0.5 0.3 0.5 0.0 0.4 0.7 0.6 0.2 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 5.2 0.3 2.6 0.0 0.1 1.5 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.6 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.1 1.8 0.4 0.0 0.0 0.0 0.9 0.0 0.2 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 1.5 0.1 0.2 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.5 0.5 0.3 0.4 0.5 0.2 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 6.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 FNDC3A "bA203I16.5, FNDC3, KIAA0970" ENSG00000102531 "Fibronectin type III domain containing 3A" Q9Y2H6 13 48975912-49209779 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008927, HPA012555, HPA012825" Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Golgi apparatus, Centrosome" Cytosol "HPA008927: AB_1078899, HPA012555: , HPA012825: AB_1848985" "unprognostic (1.54e-1)" "unprognostic (1.34e-3)" "unprognostic (8.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (2.91e-2)" "unprognostic (5.71e-2)" "unprognostic (6.17e-2)" "unprognostic (3.16e-2)" "unprognostic (1.87e-2)" "unprognostic (4.03e-2)" "prognostic favorable (4.25e-4)" "unprognostic (8.93e-3)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (6.14e-2)" 17.8 39.9 15.2 18.7 18.6 17.0 26.3 12.7 16.4 35.2 13.6 23.3 27.5 32.1 38.8 13.1 26.5 26.8 14.0 15.3 39.4 29.7 66.9 21.6 16.7 16.7 19.6 35.4 43.1 27.7 30.8 44.1 17.4 22.1 24.0 21.9 36.8 33.9 10.1 11.4 23.8 26.0 15.5 22.6 28.8 30.4 31.9 21.3 51.2 13.1 18.9 25.6 14.1 17.9 11.6 13.1 47.1 12.4 58.3 73.0 9.2 53.3 70.8 50.2 36.3 17.9 27.7 8.8 9.7 40.5 21.8 12.4 28.4 18.1 72.6 22.1 21.9 14.3 36.9 33.2 35.3 13.4 2.3 37.7 24.8 44.7 51.4 47.1 52.6 11.9 18.0 21.0 55.4 4.7 13.3 26.7 23.2 25.0 11.0 12.6 18.8 16.4 42.4 21.2 17.8 29.4 20.1 17.8 38.8 29.8 9.6 26.0 41.7 26.1 17.9 24.3 38.3 25.4 14.4 8.1 19.6 16.9 27.4 1.9 3.0 1.9 2.5 2.0 3.6 3.3 2.9 2.2 1.9 2.2 3.7 3.3 4.5 2.1 4.0 4.0 2.6 1.7 15.2 18.6 12.7 16.4 15.3 39.4 16.7 19.6 17.4 15.5 31.9 17.9 46.7 54.5 49.0 88.2 36.2 18.4 37.4 17.5 44.3 52.0 33.4 25.5 27.1 27.1 28.9 36.8 37.5 13.2 36.4 21.6 13.7 30.6 45.9 42.1 74.3 42.4 43.5 17.9 159.5 36.2 38.2 58.0 57.6 56.4 31.6 38.8 32.9 74.2 25.4 35.3 170.8 37.4 18.3 31.8 24.4 13.1 33.8 45.5 37.4 112.4 27.0 52.7 24.7 177.9 178.2 25.5 29.0 39.5 165.9 44.2 37.8 48.0 35.6 42.5 6.6 48.0 50.8 89.8 33.7 20.3 11.9 32.3 30.9 46.4 24.7 26.4 FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.2;liver: 126.9" "Cell type enhanced" "Detected in many" "Early spermatids: 255.2;Hepatocytes: 130.9;Late spermatids: 557.6;Pancreatic endocrine cells: 89.2" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 35.3;ASC diff: 34.7;HUVEC TERT2: 43.3;SH-SY5Y: 33.2;TIME: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" 34.5 124.2 55.4 2.9 54.6 0.0 26.2 59.8 69.0 7.5 40.3 5.9 1.1 4.2 2.7 24.9 3.8 12.2 11.7 58.9 56.0 11.4 126.9 4.6 1.1 64.6 57.5 38.3 11.9 36.5 11.2 2.5 63.6 11.8 1.8 10.4 9.0 3.2 4.1 4.9 3.4 5.4 56.2 5.4 5.6 27.3 59.2 0.4 5.9 4.0 2.8 6.0 8.0 56.1 0.0 0.3 19.9 35.3 34.7 21.2 0.3 8.1 16.3 5.8 5.0 1.6 0.6 0.0 0.9 25.9 7.5 0.0 13.3 4.9 5.0 0.0 2.2 1.7 0.1 18.7 12.9 0.0 0.2 18.2 2.3 10.0 2.0 26.0 43.3 0.0 1.9 0.0 21.3 0.0 0.0 0.1 12.4 0.0 0.7 0.0 0.0 0.0 3.4 0.0 0.3 33.2 0.2 0.0 0.3 2.6 0.1 0.0 39.7 5.4 2.4 2.1 6.3 0.0 0.0 0.0 29.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 54.6 59.8 69.0 58.9 56.0 64.6 57.5 63.6 56.2 59.2 56.1 14.8 0.0 0.5 5.2 0.8 3.4 3.2 0.4 5.7 9.1 8.3 12.8 2.4 14.3 0.2 0.0 4.2 0.2 0.4 0.0 3.9 72.9 255.2 1.6 18.8 10.9 0.0 2.7 20.1 48.3 0.2 17.3 6.1 2.0 5.7 5.9 10.0 130.9 0.5 0.0 18.7 0.5 0.0 3.2 5.3 557.6 15.5 1.0 3.6 5.6 1.0 23.7 0.0 10.6 2.1 89.2 0.0 11.7 0.7 11.9 0.0 0.4 0.2 12.9 0.0 34.4 15.6 5.0 8.4 1.4 2.4 0.0 1.5 1.0 0.1 1.7 FOXJ3 KIAA1041 ENSG00000198815 "Forkhead box J3" Q9UPW0 1 42176539-42335877 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067284 Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA067284: AB_2685817" "unprognostic (5.60e-2)" "unprognostic (2.26e-2)" "unprognostic (4.24e-2)" "unprognostic (5.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (3.65e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (1.72e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (4.51e-7)" "unprognostic (2.10e-1)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (5.43e-2)" 23.2 12.9 15.6 14.9 18.6 30.2 22.2 28.6 20.1 22.6 15.2 17.8 15.7 20.2 14.8 15.5 17.9 13.1 20.1 19.7 19.6 13.4 16.2 18.5 17.8 13.4 13.2 23.1 18.9 21.4 17.1 18.4 11.9 17.1 18.1 19.4 16.9 14.6 42.1 22.9 17.6 17.7 12.5 17.2 17.5 16.4 16.2 22.2 19.2 29.2 17.3 18.3 19.1 20.6 24.8 20.5 22.1 23.0 23.3 28.5 31.7 18.4 27.1 24.2 26.8 19.0 28.9 37.8 19.1 25.8 20.7 23.1 31.1 30.2 40.8 28.5 17.5 41.7 26.3 16.3 20.1 38.7 27.4 21.3 29.3 36.2 44.6 25.7 26.7 29.6 25.7 26.6 29.2 14.1 39.3 22.0 34.4 19.8 18.3 36.4 57.9 25.9 20.5 35.4 30.6 28.8 33.1 37.8 33.1 31.4 19.0 56.9 25.0 25.1 33.5 25.7 30.8 26.2 34.8 30.2 22.7 31.6 20.7 5.1 4.9 5.5 7.2 4.3 8.9 6.4 8.9 7.9 4.0 9.2 9.3 10.7 9.3 9.9 8.9 8.3 6.2 4.2 15.6 18.6 28.6 20.1 19.7 19.6 13.4 13.2 11.9 12.5 16.2 20.6 47.5 12.8 21.3 75.4 29.5 35.4 10.9 16.7 40.5 21.4 22.9 18.3 39.9 10.0 18.5 16.5 18.8 13.9 28.8 33.2 17.6 10.7 23.7 30.6 32.0 26.7 27.0 27.3 110.8 14.7 30.8 22.6 31.6 38.1 12.7 19.3 16.4 17.0 11.7 21.9 112.6 26.5 8.2 18.6 15.3 18.4 22.4 18.7 10.6 87.1 16.0 15.0 27.8 102.5 126.6 15.9 18.9 19.9 29.2 21.4 22.6 14.8 15.1 31.3 6.6 38.3 22.0 32.1 22.5 28.2 33.4 27.9 27.7 12.6 18.9 20.8 FOXK2 "ILF, ILF1" ENSG00000141568 "Forkhead box K2" Q01167 17 82519713-82644662 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027523, HPA073491" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Mitochondria" "HPA027523: AB_10601013, HPA073491: " "unprognostic (2.39e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (9.52e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (3.35e-2)" "unprognostic (2.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "unprognostic (3.80e-3)" "unprognostic (2.24e-2)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" 14.0 24.0 10.7 12.6 13.2 8.0 12.1 14.7 16.3 14.2 1.2 18.1 9.3 19.7 9.8 20.2 13.2 10.0 17.1 12.4 10.5 12.7 13.1 14.2 12.5 5.8 7.1 14.7 15.4 20.0 17.7 15.7 6.3 13.3 9.4 11.6 12.1 12.5 43.0 18.8 12.1 16.4 3.0 11.6 14.7 28.1 9.4 18.4 15.4 28.4 11.9 15.5 13.4 12.7 48.4 50.4 46.3 50.9 26.2 28.5 31.0 27.6 31.6 47.4 47.9 49.1 30.1 40.7 19.6 34.4 52.3 27.6 49.7 32.0 44.4 28.3 47.9 42.3 32.7 49.4 41.0 47.3 27.2 27.2 57.2 50.4 56.8 29.2 48.9 43.7 57.7 40.7 26.3 28.8 81.8 30.4 26.5 39.7 38.2 53.0 39.4 34.2 21.7 40.1 76.2 56.1 27.4 69.0 65.1 48.8 48.7 54.3 38.3 62.2 43.2 42.2 56.6 46.7 45.1 53.5 33.4 39.0 33.4 1.5 1.0 1.2 1.4 0.7 1.1 1.5 1.1 1.4 1.2 1.0 0.8 0.9 0.1 1.6 0.9 2.0 1.3 0.6 10.7 13.2 14.7 16.3 12.4 10.5 5.8 7.1 6.3 3.0 9.4 12.7 21.5 51.3 27.1 23.5 11.5 37.2 8.0 10.6 10.2 19.2 17.7 15.7 19.5 7.2 16.2 14.7 12.5 11.9 19.3 15.6 3.9 8.7 15.6 19.4 22.4 14.9 10.9 7.8 44.6 10.7 8.8 13.2 14.3 26.7 2.5 22.1 10.8 13.4 20.0 47.1 39.6 12.6 8.2 17.3 22.0 24.1 9.3 19.2 12.4 20.6 13.9 12.3 6.2 33.2 49.1 11.4 12.4 13.2 13.3 13.6 12.2 7.1 13.9 16.7 0.0 19.8 16.6 15.0 10.3 17.0 43.0 9.7 11.6 30.6 13.0 10.7 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FOXN4 ENSG00000139445 "Forkhead box N4" Q96NZ1 12 109277978-109309284 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 11.4" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Endometrial ciliated cells: 2.6;Ionocytes: 2.0;Respiratory ciliated cells: 1.2;Spermatocytes: 2.8;Spermatogonia: 3.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SCLC-21H: 3.5;SH-SY5Y: 3.6;U-266/70: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA050018 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Mitochondria" Cytosol "HPA050018: AB_2680992" "unprognostic (1.09e-3)" "unprognostic (9.63e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (2.52e-2)" "unprognostic (1.18e-1)" "unprognostic (3.27e-2)" "unprognostic (7.93e-3)" "unprognostic (2.30e-1)" "unprognostic (1.02e-3)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (6.00e-2)" 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.2 1.8 0.5 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.3 0.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 11.4 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.1 2.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FRMD4B "GRSP1, KIAA1013" ENSG00000114541 "FERM domain containing 4B" Q9Y2L6 3 69168782-69542583 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 39.8;hTERT-HME1: 52.7;HUVEC TERT2: 55.1;TIME: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009705 Uncertain Supported Approved "Nucleoplasm,Golgi apparatus,Centriolar satellite" NA NA 17000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Centriolar satellite" "Nucleoplasm, Golgi apparatus" "HPA009705: AB_1849147" "unprognostic (1.36e-1)" "unprognostic (2.92e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (4.59e-2)" "unprognostic (9.73e-2)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (2.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-2)" "unprognostic (8.23e-2)" "prognostic favorable (5.01e-4)" "unprognostic (1.49e-1)" "unprognostic (7.54e-2)" "unprognostic (2.79e-1)" "unprognostic (4.39e-3)" 11.0 4.8 17.5 12.3 46.7 15.5 16.1 26.9 30.9 24.9 7.0 12.8 9.1 11.3 9.3 26.8 13.2 19.2 17.4 20.8 29.3 16.3 34.5 24.8 10.9 39.4 37.1 10.9 8.2 3.7 4.0 25.5 36.3 16.9 12.9 21.9 37.1 10.5 2.3 23.0 12.5 10.5 22.7 32.3 15.0 4.7 42.0 14.1 27.1 4.6 11.2 13.7 15.8 84.0 6.7 1.8 10.4 0.3 0.2 1.5 11.3 0.5 1.7 0.8 0.5 39.8 11.3 0.8 3.5 0.5 1.0 25.9 4.9 35.3 1.2 2.2 3.3 20.4 2.6 2.3 0.7 5.2 10.2 1.7 35.2 1.0 52.7 1.6 55.1 4.7 1.6 5.8 3.0 7.7 0.5 0.8 5.6 8.9 8.5 32.2 2.8 1.0 14.8 4.6 12.1 15.6 1.7 12.2 35.5 9.3 4.6 6.8 47.1 0.6 4.3 0.4 1.8 0.6 0.3 1.2 0.4 13.5 13.5 18.3 27.6 2.3 1.9 13.8 7.0 1.6 6.3 2.8 16.9 2.0 1.9 1.8 7.1 3.8 2.3 16.8 15.4 7.7 17.5 46.7 26.9 30.9 20.8 29.3 39.4 37.1 36.3 22.7 42.0 84.0 20.6 41.7 83.6 2.9 3.6 60.7 33.4 57.8 69.4 13.8 34.4 21.7 33.4 41.5 58.5 14.7 218.9 49.9 20.3 74.4 33.2 32.6 18.9 207.9 49.3 64.3 24.5 8.6 4.2 17.3 19.7 32.1 75.4 282.6 34.7 97.5 89.3 53.6 92.6 0.0 92.7 42.1 36.7 138.7 112.7 4.0 6.5 105.2 28.4 93.7 26.3 13.5 1.0 129.2 1209.1 24.5 67.0 18.4 6.9 61.1 10.7 55.6 38.2 109.2 6.6 11.8 21.0 0.0 3.5 79.9 51.4 58.3 44.6 32.1 32.2 172.8 FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 2.9;kidney: 2.7;smooth muscle: 2.2" "Cell type enriched" "Detected in single" 19 "Distal tubular cells: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.5" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in single" 86 "olfactory bulb: 21.3" HPA000886 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" Nucleoplasm "HPA000886: AB_1079269" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.0 2.9 0.5 0.0 0.5 0.0 0.1 0.1 0.1 2.7 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" 19.8 17.5 9.6 11.8 11.0 13.0 19.7 12.2 14.5 20.8 9.1 15.0 11.7 14.6 5.3 37.3 15.8 11.6 17.1 13.1 7.9 19.7 13.4 23.5 15.6 12.9 11.3 12.2 23.0 4.0 11.6 10.4 11.4 15.8 6.7 1.7 18.0 6.5 14.8 34.0 23.8 6.6 9.5 40.8 13.4 18.0 11.5 11.1 17.8 5.1 13.6 14.6 26.4 16.2 17.8 22.1 8.7 20.4 23.0 12.0 15.6 20.1 18.1 16.7 12.7 21.2 28.5 21.9 41.9 27.6 11.6 30.3 11.3 16.9 7.0 38.8 10.6 29.9 21.5 11.7 12.4 16.9 44.8 14.9 13.2 15.7 8.2 8.9 26.6 23.2 25.5 23.5 18.3 23.9 26.6 24.6 10.2 13.0 28.7 33.7 16.6 25.2 13.5 21.8 18.9 14.0 15.0 60.1 47.7 7.7 22.0 13.7 23.6 18.4 19.7 26.1 12.3 41.0 22.5 20.4 16.0 10.7 129.8 1.1 12.4 17.7 13.1 13.2 14.1 12.5 9.6 16.7 11.3 9.6 8.8 9.8 23.0 8.2 19.6 13.4 10.8 12.3 9.6 11.0 12.2 14.5 13.1 7.9 12.9 11.3 11.4 9.5 11.5 16.2 30.3 3.2 5.8 2.0 20.5 54.3 22.5 17.7 6.2 5.4 15.4 12.6 7.4 12.8 13.8 12.9 0.0 6.4 25.8 29.3 7.9 21.0 22.3 20.1 12.1 24.8 13.1 24.0 13.4 29.1 15.5 13.0 10.7 23.1 14.0 27.3 37.5 11.0 16.0 5.0 4.9 20.5 8.2 20.2 68.7 4.6 6.2 18.7 19.6 10.3 21.6 4.3 18.6 5.0 10.3 33.8 14.0 7.2 11.9 28.1 32.8 4.6 14.3 4.5 6.6 11.4 14.4 5.3 9.6 24.9 83.5 11.4 21.9 35.2 14.6 35.7 FRYL "AF4p12, DKFZp686E205, KIAA0826, MOR2" ENSG00000075539 "FRY like transcription coactivator" O94915 4 48497357-48780322 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.5" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 1148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 13.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031106, HPA031107" Supported Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Microtubules, Cytokinetic bridge" "HPA031106: AB_10600660, HPA031107: AB_10600536" "unprognostic (7.50e-2)" "unprognostic (9.72e-3)" "unprognostic (6.68e-3)" "unprognostic (3.22e-2)" "unprognostic (5.37e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (4.80e-2)" "unprognostic (4.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.62e-2)" "unprognostic (3.32e-2)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" 8.8 5.4 12.2 13.2 43.5 15.0 7.9 26.6 22.6 8.4 0.8 37.9 10.4 8.4 3.7 6.6 6.1 8.3 8.6 12.1 19.9 8.4 5.7 9.7 13.4 34.8 23.4 7.9 5.6 20.3 2.7 10.5 31.2 6.5 36.7 29.2 6.8 6.6 4.5 10.2 12.8 9.2 22.2 10.8 10.7 6.3 25.7 16.7 7.9 12.0 13.1 10.2 3.4 81.5 19.7 11.6 26.8 16.4 11.3 16.1 14.5 18.1 17.4 17.6 21.2 9.4 14.7 25.0 14.3 19.3 32.9 11.8 17.8 28.1 37.9 14.3 6.1 45.6 11.3 4.3 7.0 31.6 16.8 11.6 10.5 24.0 24.9 16.4 26.4 21.3 14.8 9.2 22.9 9.6 34.5 10.9 4.6 8.9 9.8 25.4 35.0 4.7 15.7 20.8 23.1 9.9 17.7 5.2 9.9 12.8 6.8 19.6 40.3 19.8 25.5 10.1 35.3 12.4 17.5 22.1 16.6 20.6 19.8 13.5 0.9 1.8 2.0 1.4 1.6 1.5 1.8 1.7 1.0 1.2 2.0 1.9 2.8 2.7 1.0 1.7 1.3 0.7 12.2 43.5 26.6 22.6 12.1 19.9 34.8 23.4 31.2 22.2 25.7 81.5 87.1 38.5 33.1 92.1 50.1 47.3 24.3 32.0 38.7 45.3 23.7 17.0 33.5 18.6 28.9 16.5 135.5 23.6 59.9 122.8 3.9 13.8 11.6 48.2 29.0 74.8 79.5 80.6 110.1 11.6 21.5 23.7 128.4 56.8 46.9 25.6 48.9 15.2 19.4 47.1 172.5 195.1 38.7 30.1 34.0 3.9 17.1 40.1 26.6 214.5 35.1 32.8 63.8 146.8 1148.7 28.8 87.3 18.4 38.6 43.4 50.4 8.4 21.0 105.6 19.7 31.2 37.3 12.8 10.9 37.3 49.3 10.8 54.4 15.6 93.9 53.3 FSD1L "CCDC10, CSDUFD1, FSD1CL, FSD1NL" ENSG00000106701 "Fibronectin type III and SPRY domain containing 1 like" Q9BXM9 9 105447796-105552433 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 43.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 423.3;Early spermatids: 97.2;Excitatory neurons: 79.0;Rod photoreceptor cells: 121.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035138 Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA035138: AB_10601324" "unprognostic (9.28e-2)" "unprognostic (4.04e-3)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (3.93e-2)" "unprognostic (1.82e-2)" "unprognostic (3.17e-5)" "unprognostic (4.20e-2)" "unprognostic (5.65e-2)" "unprognostic (9.64e-3)" "unprognostic (2.66e-3)" "unprognostic (3.32e-2)" "unprognostic (8.28e-2)" "unprognostic (2.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.07e-2)" "unprognostic (1.22e-3)" 1.2 3.5 8.4 2.1 9.4 2.4 1.6 7.8 10.0 1.7 6.3 2.6 4.5 2.1 3.3 0.9 7.1 1.4 4.1 8.9 12.3 2.1 0.7 2.2 1.4 13.2 11.4 1.4 1.4 2.0 3.3 0.9 11.5 1.6 2.4 43.2 1.1 1.6 7.3 1.1 3.7 1.5 11.7 1.4 2.2 5.8 12.5 1.6 2.0 13.3 1.5 1.1 0.9 12.0 3.3 3.8 5.6 3.9 1.6 3.2 2.0 3.1 1.8 2.5 2.5 1.7 1.4 8.3 1.2 2.7 3.0 1.3 3.6 1.6 3.5 11.1 1.3 1.4 5.3 2.3 2.5 4.9 3.4 1.5 1.6 3.6 5.5 3.2 2.4 3.9 1.8 5.1 2.5 1.1 8.4 3.1 3.5 0.4 2.2 10.6 3.8 0.7 2.6 0.7 12.3 5.9 3.5 0.9 3.0 2.3 3.7 1.7 3.2 4.4 2.7 3.7 4.2 2.6 9.9 2.2 3.1 3.0 1.6 0.4 0.9 0.0 0.5 0.6 0.2 1.8 0.7 0.5 0.6 0.6 0.0 0.3 0.2 0.5 0.4 0.6 0.2 0.2 8.4 9.4 7.8 10.0 8.9 12.3 13.2 11.4 11.5 11.7 12.5 12.0 2.9 3.2 1.1 23.8 4.2 1.0 2.0 2.5 0.0 23.1 2.3 2.0 6.0 1.5 3.5 7.3 423.3 0.3 3.4 3.0 1.9 22.7 97.2 47.5 5.7 3.3 10.7 1.7 79.0 3.8 1.3 5.2 2.6 15.1 14.0 10.4 1.1 1.3 3.8 52.2 59.2 6.3 2.0 1.2 3.5 68.2 5.0 5.3 10.6 16.9 21.0 12.7 1.0 21.6 66.9 5.2 7.1 6.8 3.0 1.1 7.8 2.4 44.9 121.1 13.1 6.3 4.1 26.0 26.1 0.3 0.9 0.0 2.8 2.2 6.8 0.2 FTSJ3 SPB1 ENSG00000108592 "FtsJ RNA 2'-O-methyltransferase 3" Q8IY81 17 63819433-63830012 "Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055544, HPA062628" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA055544: AB_2682843, HPA062628: AB_2684813" "unprognostic (1.33e-1)" "unprognostic (1.41e-1)" "unprognostic (6.60e-2)" "unprognostic (7.82e-2)" "unprognostic (6.45e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.27e-1)" "unprognostic (2.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.85e-1)" "unprognostic (1.12e-1)" "unprognostic (4.99e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (5.10e-1)" "unprognostic (3.43e-1)" 20.7 20.7 11.8 18.2 12.4 15.8 18.0 12.3 12.7 20.4 12.0 20.5 14.2 20.2 17.2 19.0 18.8 15.1 20.8 11.3 12.0 23.3 18.8 14.8 20.9 12.6 12.1 22.3 15.7 20.6 12.4 13.1 12.5 18.7 18.0 8.8 17.7 18.1 28.8 23.9 18.4 22.6 12.3 21.0 17.8 15.2 12.3 21.0 17.2 14.6 23.8 20.1 18.7 12.7 63.0 97.0 36.8 52.5 57.9 49.5 57.0 61.4 44.7 68.8 54.2 81.4 40.9 83.4 24.7 36.2 36.0 42.6 69.3 58.4 87.8 14.4 69.2 75.0 68.6 76.6 42.2 95.9 52.5 35.1 45.3 106.9 51.2 34.9 58.2 50.2 75.9 33.1 46.5 105.5 84.9 31.1 99.4 70.2 97.7 74.6 100.9 58.6 44.8 56.3 33.9 132.5 72.3 60.9 43.1 72.7 58.0 31.8 52.7 50.9 71.6 57.4 115.1 79.5 120.9 81.4 45.6 62.6 50.3 4.5 11.4 7.0 11.0 13.0 14.5 9.6 11.6 14.5 13.6 8.6 9.2 11.5 2.5 13.9 10.1 10.3 15.1 10.0 11.8 12.4 12.3 12.7 11.3 12.0 12.6 12.1 12.5 12.3 12.3 12.7 16.2 32.1 30.2 4.2 17.3 13.8 13.6 16.1 26.7 6.6 10.6 12.6 27.7 18.6 25.7 14.7 10.4 16.0 19.4 15.7 13.7 28.0 8.8 23.5 27.5 25.1 12.7 20.8 2.0 33.8 17.0 18.4 11.2 24.1 24.1 17.5 14.3 19.9 14.2 3.3 2.0 12.0 16.2 13.8 9.3 17.8 24.2 16.3 8.8 1.9 19.3 16.0 15.5 1.5 3.8 30.6 14.0 19.2 18.6 10.6 15.5 29.8 24.3 9.3 46.0 21.0 20.5 11.7 15.7 20.8 12.8 16.3 18.6 15.7 21.1 9.5 FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 140.0;Early spermatids: 248.8;Late spermatids: 334.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: AB_2682327, HPA058655: AB_2683789" "unprognostic (6.02e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-3)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" "unprognostic (4.80e-2)" "unprognostic (5.40e-3)" "unprognostic (6.07e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-3)" "unprognostic (2.76e-4)" "unprognostic (3.06e-3)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-3)" "unprognostic (6.01e-3)" 1.9 2.2 4.3 1.0 4.7 0.8 3.4 4.2 4.2 4.0 2.0 2.5 2.5 3.1 1.2 1.9 3.3 1.8 1.7 3.0 3.3 3.1 2.0 2.4 1.8 4.3 5.5 5.2 2.6 5.1 1.3 3.5 3.3 2.2 2.7 5.2 2.7 2.1 0.6 3.2 2.6 2.9 2.7 1.5 2.3 1.5 4.8 2.9 2.8 1.2 2.2 2.2 2.2 2.5 2.4 4.5 6.8 8.3 10.8 10.8 3.4 4.3 7.1 4.2 5.4 6.3 3.6 2.7 5.1 5.8 3.5 5.9 10.4 4.1 4.1 5.8 3.8 8.6 3.6 7.0 4.9 1.9 2.9 8.0 7.0 1.1 5.4 8.8 8.6 4.4 8.0 3.2 3.9 1.4 6.6 2.8 9.1 6.4 3.0 4.8 5.1 1.4 6.1 5.4 2.4 2.3 2.5 3.7 5.1 7.0 3.8 1.9 6.6 3.2 1.4 8.1 3.6 1.3 2.2 1.8 2.0 5.4 3.4 0.4 0.6 0.7 1.3 0.2 1.4 1.0 0.7 1.2 1.3 0.3 0.8 0.8 0.4 1.6 0.2 0.7 1.7 0.6 4.3 4.7 4.2 4.2 3.0 3.3 4.3 5.5 3.3 2.7 4.8 2.5 4.5 3.2 2.0 140.0 2.5 2.7 2.7 3.4 4.0 2.9 3.7 3.8 2.5 2.8 3.2 3.7 10.4 12.0 3.0 1.5 1.9 4.5 248.8 2.8 5.7 3.8 3.6 3.8 16.3 4.0 7.0 5.8 6.1 3.0 5.7 10.1 5.3 3.6 3.4 3.3 20.2 3.2 4.1 2.2 1.8 334.2 6.8 2.2 1.8 29.0 3.0 29.9 5.2 44.2 16.4 4.0 1.0 4.9 5.0 1.4 5.3 3.0 2.0 11.0 0.0 5.7 4.6 7.0 2.7 5.5 1.7 6.0 2.6 6.5 3.6 1.3 FUT8 ENSG00000033170 "Fucosyltransferase 8" Q9BYC5 14 65410592-65744121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1019.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 15.6;NK-cells: 14.8;T-cells: 10.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017129, HPA043410" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB017129: , HPA043410: AB_2678467" "unprognostic (1.67e-1)" "unprognostic (1.63e-1)" "unprognostic (3.28e-2)" "unprognostic (1.65e-3)" "unprognostic (2.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (2.00e-2)" "unprognostic (1.33e-3)" "unprognostic (8.09e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-3)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" 7.9 8.2 21.0 11.9 38.2 3.6 10.5 44.1 28.2 6.9 0.0 11.4 17.5 9.0 5.3 6.8 15.6 11.1 4.7 20.4 27.7 6.9 3.4 8.1 11.7 32.8 29.9 7.3 9.9 9.6 4.6 17.3 29.3 5.8 11.6 8.3 42.6 10.5 2.5 5.3 17.4 11.0 29.4 10.2 31.8 16.4 29.7 11.3 8.4 6.3 18.6 13.3 4.5 64.3 115.9 22.5 12.6 110.6 49.5 38.4 61.6 35.9 64.8 30.3 32.6 16.9 44.8 30.7 29.2 40.1 79.4 9.0 29.9 11.4 45.6 124.2 11.0 33.5 7.2 23.0 26.8 7.6 23.9 96.0 6.8 39.3 19.4 124.4 69.6 17.1 14.1 28.8 20.8 60.8 36.6 16.7 14.7 59.6 66.6 26.9 10.3 17.2 46.5 33.1 23.4 16.6 20.8 9.8 8.0 70.6 10.2 12.9 141.8 34.5 36.0 15.3 30.5 47.3 18.5 74.3 68.6 13.6 11.1 0.7 2.0 0.7 3.6 0.9 3.8 15.6 6.2 5.6 2.6 8.3 6.6 6.6 0.3 14.8 1.4 2.6 10.0 2.9 21.0 38.2 44.1 28.2 20.4 27.7 32.8 29.9 29.3 29.4 29.7 64.3 19.0 12.8 32.5 227.5 43.1 12.1 7.4 11.5 17.1 10.1 18.3 11.7 5.9 8.6 18.9 12.9 4.2 45.5 8.3 5.9 0.0 9.1 37.9 9.9 14.6 16.0 5.4 15.8 169.0 31.7 28.1 22.7 78.0 10.2 7.6 3.3 14.6 3.5 13.0 8.4 166.4 26.5 2.0 12.2 8.6 15.3 12.8 10.2 1.8 70.3 3.6 27.8 9.2 138.7 1019.1 54.7 10.3 13.5 124.3 8.8 24.5 8.4 15.3 9.1 0.0 14.3 13.2 34.6 26.8 7.4 9.8 14.1 18.9 10.6 21.7 7.2 FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 18.9;stomach 1: 23.2" "Cell type enhanced" "Detected in some" "Astrocytes: 776.4;Excitatory neurons: 333.5;Inhibitory neurons: 238.2;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 224.7" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.9;OE19: 2.8;RT4: 6.5;SCLC-21H: 6.3;SK-BR-3: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: AB_2686323" "unprognostic (1.60e-1)" "unprognostic (2.48e-1)" "unprognostic (5.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.43e-3)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" 0.0 0.4 10.5 0.0 12.6 0.0 0.6 14.5 11.7 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 11.8 13.6 0.2 0.0 0.0 0.0 3.4 18.9 0.0 4.8 0.0 0.4 0.4 3.2 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 5.5 0.0 23.2 0.0 15.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.4 2.8 0.0 0.0 0.0 0.0 0.0 6.5 6.3 0.1 0.0 3.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 12.6 14.5 11.7 11.8 13.6 3.4 18.9 3.2 5.5 15.3 6.4 0.0 0.0 0.0 776.4 0.2 0.0 0.6 0.0 0.0 4.2 1.4 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.1 1.3 0.0 0.0 333.5 2.0 0.0 0.1 56.1 1.4 0.0 0.4 0.0 0.0 0.1 0.0 238.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.2 0.0 168.9 224.7 0.5 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.2 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Kupffer cells: 9.8;Leydig cells: 23.3;Peritubular cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 53.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 1.5 1.6 1.0 1.4 1.5 0.2 1.3 0.9 1.2 5.9 10.5 1.8 0.9 5.3 1.3 0.9 3.8 1.8 2.8 1.1 1.3 2.8 0.2 2.9 0.8 1.3 1.9 3.3 1.5 2.1 1.1 3.6 2.0 1.7 0.4 0.7 1.0 1.9 0.4 0.6 1.6 1.5 1.3 2.1 1.2 1.5 1.4 0.3 2.4 0.7 0.7 2.0 2.5 1.6 12.9 37.7 38.3 13.8 8.7 6.4 0.4 39.5 30.4 53.4 38.2 28.4 6.2 0.0 8.9 13.9 13.1 5.5 3.6 2.8 30.2 2.9 7.2 1.7 6.6 0.1 7.7 0.2 7.5 10.7 2.8 9.6 8.8 40.8 1.8 4.9 2.5 0.3 20.9 5.9 6.7 3.6 26.8 0.1 6.7 18.1 8.6 1.9 7.7 0.6 3.8 10.9 5.2 1.1 2.3 32.4 14.6 8.4 0.7 24.1 17.5 4.4 22.6 0.8 0.7 3.0 4.0 2.4 11.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 1.0 1.5 0.9 1.2 1.1 1.3 1.3 1.9 2.0 1.3 1.4 1.6 0.5 19.2 0.0 1.6 0.6 0.6 0.3 0.9 0.0 0.0 0.9 2.9 1.9 0.0 0.2 1.8 0.0 1.6 1.8 0.0 0.0 0.3 0.6 1.1 8.4 0.7 1.2 1.3 0.0 1.8 0.5 5.9 0.0 1.5 0.0 1.4 0.7 0.0 4.8 0.0 0.0 0.3 0.0 9.8 6.0 0.4 23.3 5.6 0.0 6.5 6.2 6.0 0.0 0.0 0.2 0.7 0.0 18.0 0.3 0.1 0.0 0.3 0.2 0.4 0.0 0.4 5.3 0.3 1.2 0.3 0.4 2.3 0.2 2.4 0.0 0.0 G2E3 "FLJ20333, KIAA1333, PHF7B" ENSG00000092140 "G2/M-phase specific E3 ubiquitin protein ligase" Q7L622 14 30559158-30620064 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.3" "Group enriched" "Detected in all" 6 "Early spermatids: 722.5;Late spermatids: 233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001601 Uncertain Approved "Golgi apparatus,Vesicles,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Golgi apparatus, Vesicles" "HPA001601: AB_1079198" "unprognostic (4.75e-2)" "unprognostic (6.31e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (9.10e-2)" "unprognostic (3.99e-2)" "unprognostic (5.44e-6)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (1.86e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (2.32e-2)" "unprognostic (2.12e-2)" 4.8 3.2 2.1 6.4 7.0 10.0 6.4 11.6 5.5 6.4 0.7 5.6 5.0 6.3 3.7 6.2 4.8 3.8 4.8 2.4 5.6 4.5 5.2 4.5 9.1 3.1 2.5 6.1 5.2 5.6 2.7 6.3 2.7 5.1 5.3 13.8 4.9 4.6 3.0 5.9 4.9 6.2 1.0 6.3 5.3 42.3 7.0 14.3 6.6 3.9 8.9 4.9 3.9 9.6 37.9 15.6 33.7 16.1 11.2 15.0 30.5 31.9 12.9 20.2 22.9 17.1 20.5 32.9 10.9 18.4 15.9 29.7 36.4 18.8 42.2 25.7 15.7 19.6 17.1 31.0 10.3 34.0 22.5 8.1 7.4 15.1 34.9 18.3 22.9 22.5 21.2 24.2 29.0 21.9 22.6 9.6 31.2 27.5 32.7 21.4 0.0 8.2 10.5 22.3 28.4 19.9 27.7 16.0 7.9 20.5 19.1 12.5 17.3 19.7 21.9 16.9 21.9 14.1 47.7 38.8 5.4 16.6 29.2 20.2 6.5 12.9 7.6 8.5 10.1 9.2 7.4 6.3 5.6 9.9 9.2 7.8 5.9 6.5 11.3 6.8 6.6 4.1 2.1 7.0 11.6 5.5 2.4 5.6 3.1 2.5 2.7 1.0 7.0 9.6 22.6 19.2 9.0 17.9 32.9 21.9 22.5 11.8 26.7 34.9 13.0 10.8 10.0 12.8 13.6 5.5 25.0 17.8 23.0 9.0 9.8 8.9 722.5 13.9 26.6 17.0 13.8 42.7 45.3 7.1 22.7 20.6 14.3 14.1 17.1 23.3 13.2 7.5 14.2 35.3 38.4 14.7 14.2 13.9 12.4 233.9 16.4 16.5 8.8 24.4 16.2 15.5 32.0 41.7 43.1 10.7 9.4 14.3 14.4 22.5 5.6 12.0 10.9 33.4 52.6 18.0 18.6 69.8 42.7 20.7 25.4 10.0 24.9 11.9 12.4 20.6 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GAB3 ENSG00000160219 "GRB2 associated binding protein 3" Q8WWW8 X 154675249-154751583 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 20.4;dendritic cells: 32.0;Erythroid cells: 20.4;granulocytes: 20.8;Kupffer cells: 24.7;Microglial cells: 30.9;NK-cells: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 23.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA010090 Approved Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA010090: AB_1849362" "unprognostic (2.67e-2)" "unprognostic (1.04e-2)" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (3.63e-3)" "unprognostic (1.20e-1)" "unprognostic (5.90e-3)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.04e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.22e-1)" "unprognostic (2.84e-2)" "unprognostic (5.87e-2)" "unprognostic (2.19e-1)" 3.7 2.1 1.8 7.0 3.5 12.5 2.3 2.6 3.4 1.8 2.2 2.6 3.4 2.0 3.8 1.7 1.9 3.7 7.4 2.0 2.6 1.0 1.9 6.0 7.6 4.7 2.2 1.3 1.0 2.7 0.4 3.7 5.0 1.3 3.4 1.2 2.1 1.9 1.3 3.6 4.2 3.5 2.1 13.9 2.6 4.9 3.6 5.2 3.6 1.6 6.6 3.1 1.1 8.6 0.8 0.0 0.7 1.0 0.9 2.3 0.5 0.3 0.6 0.2 0.3 0.0 0.5 2.5 0.7 0.0 1.5 0.4 0.6 0.4 0.0 2.9 1.0 21.3 2.9 2.4 1.6 6.5 23.3 0.9 0.2 2.0 0.8 0.8 5.2 2.0 4.8 7.3 1.0 0.3 2.4 6.6 0.2 0.0 0.1 3.5 0.0 0.3 1.3 0.0 3.0 0.4 0.3 0.3 0.4 0.5 0.9 3.7 4.8 1.2 1.9 0.8 0.6 8.0 7.0 2.5 2.0 8.4 0.6 26.4 5.9 8.7 13.3 5.7 10.2 1.0 3.5 9.7 5.8 1.3 1.2 6.8 9.0 2.5 3.6 3.3 0.8 5.0 1.8 3.5 2.6 3.4 2.0 2.6 4.7 2.2 5.0 2.1 3.6 8.6 9.9 0.0 6.7 0.7 6.0 0.6 0.0 0.3 0.0 0.1 0.2 0.6 20.4 0.0 1.3 0.0 0.0 0.1 32.0 0.0 0.0 0.8 0.3 0.5 1.2 8.3 0.0 20.4 0.3 0.5 0.6 2.3 0.0 0.1 20.8 2.2 6.1 0.3 13.8 0.0 0.3 0.0 0.0 24.7 5.8 1.7 1.8 18.8 0.0 30.9 16.1 2.6 39.1 8.5 0.3 0.4 0.0 4.5 7.5 0.1 0.0 0.2 1.7 0.4 6.6 0.7 6.6 0.1 1.0 0.2 1.0 0.1 18.6 0.5 0.0 0.1 GABARAPL2 "ATG8, ATG8C, GATE-16, GATE16, GEF2" ENSG00000034713 "GABA type A receptor associated protein like 2" P60520 16 75566375-75577881 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036726 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA036726: AB_10672476" "unprognostic (3.29e-2)" "unprognostic (3.16e-2)" "unprognostic (1.30e-2)" "unprognostic (7.00e-2)" "unprognostic (4.44e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.58e-1)" "unprognostic (6.85e-2)" "unprognostic (2.13e-1)" "unprognostic (4.95e-2)" "unprognostic (9.86e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.95e-8)" "unprognostic (3.11e-3)" "unprognostic (3.84e-3)" "unprognostic (1.37e-2)" "unprognostic (3.85e-1)" 129.2 166.9 269.1 68.0 278.1 101.6 122.3 297.7 310.8 105.9 237.2 118.5 67.1 101.3 158.1 91.9 106.0 84.1 279.9 259.7 294.9 153.8 113.6 111.3 94.7 280.8 278.4 108.7 81.4 209.5 169.0 113.8 289.2 113.7 81.4 201.4 100.8 102.2 262.9 135.0 90.1 98.6 306.0 112.0 99.7 78.3 282.4 102.1 124.5 186.7 98.9 95.3 104.8 320.2 103.4 85.9 142.7 67.7 217.1 189.9 72.6 118.2 169.9 158.0 176.4 79.8 129.1 148.1 143.0 135.3 95.2 86.6 107.6 110.6 193.9 64.8 208.7 86.9 72.2 119.1 118.2 84.1 151.3 132.0 153.5 133.3 98.6 143.0 130.5 130.5 130.3 58.4 160.2 145.7 125.4 161.0 85.8 114.5 95.8 139.4 69.0 179.6 166.2 66.4 167.7 175.5 184.7 43.7 177.4 113.3 140.1 130.4 119.5 67.9 104.7 100.0 64.5 166.2 172.8 310.6 163.6 80.6 102.6 345.1 148.8 370.8 128.4 140.3 163.0 215.0 135.2 146.8 176.8 199.0 121.4 114.6 502.5 115.3 157.0 274.1 208.1 241.5 269.1 278.1 297.7 310.8 259.7 294.9 280.8 278.4 289.2 306.0 282.4 320.2 341.0 86.6 136.2 30.7 163.9 274.9 278.8 311.4 141.7 247.9 196.5 236.2 361.4 145.8 212.5 174.7 45.9 251.3 188.5 201.5 686.7 183.9 48.2 209.6 112.8 270.1 277.8 457.6 37.0 175.4 120.6 203.5 80.5 162.4 110.1 85.9 239.8 128.5 223.9 307.9 39.6 156.4 297.0 169.6 428.8 59.7 243.5 197.2 257.9 21.5 404.6 491.0 145.2 27.6 63.6 223.6 237.0 261.1 137.5 306.1 195.7 552.4 263.0 208.1 157.8 182.1 187.9 288.1 219.9 136.6 273.9 390.1 159.3 182.5 121.2 328.6 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 8 "Inhibitory neurons: 392.8;Oligodendrocyte precursor cells: 146.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 20.1;HEL: 64.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 0.2 3.0 22.1 0.0 29.9 3.3 0.1 15.5 33.0 1.0 0.0 0.0 0.0 1.6 4.3 0.4 0.2 0.1 0.0 17.1 98.5 4.8 0.1 0.2 0.1 12.4 41.6 0.2 0.2 46.3 5.0 0.4 17.6 0.8 0.1 29.7 0.1 0.3 0.0 0.2 0.1 0.0 12.7 0.1 0.0 3.2 31.1 0.8 0.1 0.0 0.2 0.6 0.4 14.2 18.2 0.7 0.0 7.3 0.0 0.0 0.1 0.4 0.0 2.6 1.7 4.6 6.7 0.0 0.9 0.5 2.9 20.1 2.3 0.6 1.6 2.8 13.4 64.5 6.0 0.2 0.0 0.3 1.1 0.0 5.5 0.0 2.3 0.6 0.1 0.5 17.0 0.3 0.8 1.5 0.0 0.0 8.1 9.7 6.7 1.0 4.6 0.4 8.5 9.4 6.7 2.1 12.6 0.0 3.5 0.6 0.2 0.0 0.0 12.0 1.7 2.4 7.0 0.0 0.0 0.1 11.5 3.2 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 29.9 15.5 33.0 17.1 98.5 12.4 41.6 17.6 12.7 31.1 14.2 0.0 0.0 0.0 14.7 0.0 0.3 2.1 7.7 2.2 32.5 0.1 0.1 1.3 0.0 3.6 0.0 10.4 0.0 0.0 0.2 7.9 4.5 5.6 4.4 0.4 0.4 3.0 5.5 2.6 5.6 0.1 0.2 0.0 2.9 0.0 5.5 0.0 0.0 4.0 5.0 392.8 0.3 2.0 0.8 0.4 6.2 0.6 0.5 0.0 7.5 0.0 4.9 0.0 146.8 7.6 2.9 0.0 0.0 0.1 0.9 0.0 0.0 4.7 6.0 0.0 0.0 1.2 4.4 7.7 0.6 0.1 0.5 0.0 0.1 0.1 0.4 GAGE1 CT4.1 ENSG00000205777 "G antigen 1" P0DTW1 X 49599025-49608536 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 49 "testis: 9.1" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 113.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AN3-CA: 739.9" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 739.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.5 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 24.4 113.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE10 ENSG00000215274 "G antigen 10" A6NGK3 X 49303669-49319844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;testis: 1.6" "Cell type enhanced" "Detected in some" "Granulosa cells: 2.1;Leydig cells: 1.2;Microglial cells: 1.0;Peritubular cells: 1.2;Spermatocytes: 3.2;Spermatogonia: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.5;WM-115: 1.0" HPA043232 Supported Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" "unprognostic (2.81e-2)" "unprognostic (2.26e-1)" "unprognostic (3.97e-1)" 0.0 0.0 1.0 0.0 1.4 0.0 0.2 0.9 2.0 0.1 0.8 0.1 0.0 0.1 0.5 0.0 0.4 0.0 0.1 1.0 0.8 0.0 0.0 0.0 0.2 0.9 1.1 0.9 0.0 0.0 0.8 0.0 1.0 0.1 0.1 0.6 0.0 0.3 0.1 0.0 0.0 0.3 0.9 0.1 0.0 1.6 0.8 0.0 0.2 0.0 0.1 0.1 0.0 1.0 0.0 0.0 0.2 2.5 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.9 2.0 1.0 0.8 0.9 1.1 1.0 0.9 0.8 1.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.2 5.2 0.0 0.1 0.0 0.0 0.6 0.0 0.1 GAGE12C ENSG00000237671 "G antigen 12C" A1L429 X 49532211-49539538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 271 "testis: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/84: 37.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 9.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12D ENSG00000227488 "G antigen 12D" A1L429 X 49541767-49549094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 271 "testis: 27.0" "Cell type enriched" "Detected in single" 10 "Spermatogonia: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/84: 37.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 9.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12E ENSG00000216649 "G antigen 12E" A1L429 X 49551333-49558649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.8" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.4;U-266/84: 2.1" HPA043232 Supported Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12F ENSG00000236362 "G antigen 12F" "P0CL80, O76087, P0CL82" X 49551278-49568218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 178.7" "Cell type enhanced" "Detected in single" "Spermatogonia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "AN3-CA: 1630.3;K-562: 1415.3" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.7 178.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.9 0.0 0.0 1630.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.1 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1415.3 30.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 360.9 0.0 5.1 56.9 7.5 0.3 1.0 0.6 72.0 0.0 0.2 0.0 171.2 1.3 11.5 4.6 4.8 12.1 3.4 8.4 12.6 8.7 0.0 7.8 9.7 8.6 1.4 14.7 10.5 12.4 20.2 11.5 0.4 0.6 0.2 0.3 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12G ENSG00000215269 "G antigen 12G" "P0CL81, O76087, P0CL82" X 49570434-49577754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "retina: 1.6;stomach 1: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 4.7" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 8 "AN3-CA: 439.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 23: AN3-CA - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 439.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 54.7 0.0 0.0 8.4 0.5 0.1 0.2 0.0 0.0 0.0 0.2 0.0 20.8 0.2 1.5 0.9 0.5 1.6 0.8 0.8 2.0 0.2 0.0 1.5 0.3 1.7 0.0 0.3 1.4 0.9 4.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12H ENSG00000224902 "G antigen 12H" A6NDE8 X 49579983-49587301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 230 "testis: 22.9" "Group enriched" "Detected in some" 15 "Spermatocytes: 1.4;Spermatogonia: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "A-431: 53.9;U-266/84: 164.9" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.3 1.4 0.0 0.0 0.0 164.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12J GAGE11 ENSG00000224659 "G antigen 12J" A6NER3 X 49322057-49329384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 35.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "AN3-CA: 1145.9;K-562: 290.3" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 35.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1145.9 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 2.1 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 290.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 32.4 0.0 0.0 0.0 0.2 0.5 0.0 2.5 32.2 0.1 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE13 GAGE12A ENSG00000274274 "G antigen 13" Q4V321 X 49331616-49338952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 36.1" "Group enriched" "Detected in some" 22 "Spermatocytes: 4.2;Spermatogonia: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AN3-CA: 303.6;T-47d: 165.3;WM-115: 83.9" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 303.6 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 3.6 0.0 2.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 165.3 0.0 0.7 3.4 1.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 83.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE2A "CT4.2, GAGE2" ENSG00000189064 "G antigen 2A" Q6NT46 X 49589529-49596827 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 108 "testis: 92.5" "Group enriched" "Detected in some" 17 "Spermatocytes: 108.0;Spermatogonia: 358.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 86.8;T-47d: 289.7;WM-115: 325.3" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" "unprognostic (1.29e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 86.8 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.0 289.7 0.0 0.0 47.3 10.6 0.1 0.0 1.2 13.8 0.0 2.9 0.0 325.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 108.0 358.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE2E GAGE8 ENSG00000275113 "G antigen 2E" Q4V326 X 49341192-49345922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 13 "stomach 1: 12.8;testis: 26.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "AN3-CA: 2587.1;K-562: 674.0" HPA043232 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.2 12.8 26.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2587.1 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 4.3 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.7 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 674.0 12.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.2 0.0 5.0 0.3 0.3 364.7 0.1 3.3 61.8 2.4 0.2 0.2 0.8 20.9 0.0 0.7 0.2 138.5 0.4 0.6 0.1 0.5 0.0 0.0 0.6 0.1 1.0 0.0 1.2 2.1 0.0 0.4 0.4 0.0 1.5 2.9 0.1 0.1 0.3 0.0 0.3 0.2 0.0 0.1 0.5 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 65.8" "Cell type enhanced" "Detected in many" "Microglial cells: 74.0;Oligodendrocyte precursor cells: 156.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 284.9;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: AB_1849443" "unprognostic (6.99e-2)" "unprognostic (4.33e-2)" "unprognostic (9.85e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.63e-1)" "unprognostic (6.98e-2)" "unprognostic (6.95e-3)" "unprognostic (2.38e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-3)" "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-1)" 12.1 15.6 10.7 14.4 14.5 19.3 13.5 12.1 10.0 24.1 33.0 16.1 14.4 6.3 6.0 4.9 14.6 16.7 9.0 9.5 12.5 9.7 4.4 15.5 9.9 16.1 13.9 65.8 9.8 13.6 11.5 4.7 12.3 9.1 14.7 7.8 13.5 3.7 5.4 6.0 12.6 11.6 9.9 15.8 22.0 4.5 13.9 7.8 16.6 8.2 9.4 11.1 5.2 12.6 25.6 85.3 20.3 17.8 42.2 37.3 15.6 71.7 39.9 27.9 26.7 12.1 56.7 16.6 49.3 121.4 49.9 4.4 9.4 56.0 25.4 43.2 6.7 45.4 16.0 16.5 32.4 9.9 42.3 46.7 12.9 22.7 33.2 284.9 54.4 12.5 10.5 50.9 48.4 26.4 1.1 6.8 8.0 71.1 17.3 5.1 10.7 16.6 38.6 17.1 2.7 6.6 31.8 117.0 9.4 29.6 45.6 7.4 161.2 67.5 15.9 16.8 77.7 14.5 15.0 8.7 44.2 19.3 21.1 2.0 1.2 2.4 3.1 1.6 2.8 1.9 1.8 2.0 1.4 2.1 0.8 2.1 2.5 1.9 1.8 1.1 1.6 1.0 10.7 14.5 12.1 10.0 9.5 12.5 16.1 13.9 12.3 9.9 13.9 12.6 17.4 9.6 46.4 32.7 17.4 4.8 3.9 5.6 1.8 4.6 12.4 8.6 5.0 5.7 8.7 14.7 4.2 0.7 27.7 23.0 9.8 9.1 10.3 12.4 7.4 14.1 3.0 21.4 14.3 30.1 1.5 13.7 30.5 22.3 10.2 10.5 23.9 5.3 8.5 0.0 15.9 20.4 6.1 19.5 7.8 22.5 38.2 12.4 0.0 74.0 11.9 17.4 44.3 156.9 66.9 36.8 13.6 50.0 15.4 8.2 15.3 2.7 0.7 10.5 6.6 5.6 7.8 2.0 4.0 1.2 3.7 0.8 21.7 27.3 12.2 4.2 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 74.7;intestine: 55.8;stomach 1: 54.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.2;Intestinal goblet cells: 142.4;Undifferentiated cells: 42.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 128.4;U-2197: 160.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 5.0 2.0 1.2 7.7 1.3 2.2 3.4 6.5 1.8 8.7 4.3 55.3 34.2 3.7 74.7 19.6 7.5 10.5 1.2 1.1 1.4 4.8 0.4 11.7 3.2 2.6 1.4 0.4 13.6 6.3 3.4 2.6 2.7 4.6 55.8 0.6 25.5 4.3 1.3 3.4 27.1 14.0 1.1 2.2 54.8 4.6 1.5 3.3 14.7 0.6 6.1 11.9 4.6 1.6 5.4 4.1 3.4 13.5 10.0 7.8 0.0 1.4 2.1 2.0 4.6 0.8 21.6 0.0 5.0 0.9 12.2 38.0 2.9 1.3 1.6 26.2 1.7 2.4 0.2 0.0 0.5 1.6 0.5 3.8 0.9 6.4 0.0 2.7 2.3 19.3 30.2 0.0 0.6 13.9 2.6 4.7 16.7 128.4 5.6 6.5 0.3 0.1 2.3 7.7 12.4 1.1 0.5 30.6 3.0 7.7 4.5 4.5 4.3 0.0 0.3 160.9 0.0 2.1 4.8 2.3 37.1 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.4 0.2 0.0 0.1 0.6 0.3 0.0 0.6 0.0 0.1 0.0 0.1 1.2 1.3 6.5 1.8 1.1 1.4 2.6 1.4 2.7 1.1 1.5 1.6 1.3 3.2 25.7 2.0 2.3 2.4 1.3 8.3 1.2 2.4 0.4 0.1 1.0 18.6 16.9 11.0 16.7 1.0 2.6 101.2 0.0 11.2 1.8 4.8 1.6 1.6 19.9 1.3 7.4 25.4 1.7 12.5 32.1 8.7 2.5 2.4 0.0 0.0 2.3 0.0 5.7 142.4 2.0 0.3 3.9 1.4 2.1 3.9 0.0 3.7 0.2 0.8 3.1 3.5 7.0 32.0 36.5 7.5 1.7 7.4 21.9 2.7 16.9 0.2 0.0 0.7 1.5 5.9 10.5 9.9 1.3 1.1 4.5 5.1 42.5 11.1 GALNT17 "GalNAc-T17, GalNAc-T19, GalNAc-T5L, GALNTL3, ppGalNAc-T17, WBSCR17" ENSG00000185274 "Polypeptide N-acetylgalactosaminyltransferase 17" Q6IS24 7 71132144-71713600 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.0;choroid plexus: 46.0;heart muscle: 43.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Endometrial stromal cells: 7.4;Fibroblasts: 1.5;Granulosa cells: 1.7;Theca cells: 2.3" "Cancer enhanced" "Detected in many" "prostate cancer: 8.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.3;NTERA-2: 10.8;RPMI-8226: 12.6;SK-BR-3: 45.7;SuSa: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013624, HPA047986" Approved Uncertain "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Golgi apparatus" "Nucleoli, Nuclear bodies" "HPA013624: AB_1858787, HPA047986: " "unprognostic (2.79e-2)" "unprognostic (6.83e-2)" "unprognostic (5.54e-2)" "unprognostic (3.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (6.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.00e-1)" "prognostic favorable (4.60e-4)" "unprognostic (2.00e-1)" "unprognostic (4.73e-1)" "unprognostic (1.96e-2)" "unprognostic (9.63e-3)" "prognostic favorable (3.91e-4)" "unprognostic (1.92e-1)" "unprognostic (7.94e-3)" 3.2 8.7 30.5 1.9 37.9 0.0 2.0 35.9 51.2 4.0 46.0 16.6 0.3 16.6 3.1 9.3 8.7 2.5 43.5 55.0 3.2 5.7 0.4 9.3 0.0 2.1 3.8 31.6 10.1 1.2 13.3 0.2 3.0 14.7 1.0 3.3 3.3 8.2 4.7 2.2 3.9 8.3 0.0 3.4 2.4 5.0 11.2 2.6 10.1 2.9 1.5 21.2 3.3 24.8 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.7 0.0 0.0 45.7 0.0 14.1 0.0 0.0 0.0 0.0 3.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 37.9 35.9 51.2 55.0 3.2 2.1 3.8 3.0 0.0 11.2 24.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.1 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 GALNT18 "GalNAc-T18, GALNT15, GALNTL4, MGC71806" ENSG00000110328 "Polypeptide N-acetylgalactosaminyltransferase 18" Q6P9A2 11 11270877-11622005 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 149.5;Excitatory neurons: 104.4;Inhibitory neurons: 156.3;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 42.1;HaCaT: 52.4;HBEC3-KT: 36.5;PC-3: 36.4;RPMI-8226: 39.3;SK-BR-3: 47.2;U-87 MG: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012955, HPA070681" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Vesicles, Cytosol" "HPA012955: AB_1849460, HPA070681: " "unprognostic (1.26e-1)" "unprognostic (2.80e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (7.37e-2)" "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (6.68e-2)" "unprognostic (6.04e-2)" "unprognostic (2.05e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-1)" "unprognostic (2.66e-3)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.81e-2)" 18.0 4.7 19.1 4.1 17.7 0.0 15.6 17.1 20.8 13.0 10.7 24.8 3.0 24.0 2.4 7.7 12.0 11.2 26.9 29.5 12.9 26.5 10.5 51.2 5.4 12.2 17.2 4.9 8.2 9.8 6.4 24.4 13.9 13.0 3.2 3.6 17.0 9.3 10.7 13.0 8.8 13.3 12.3 3.6 6.8 14.7 19.7 6.3 42.8 6.2 3.3 11.7 11.5 12.9 42.1 15.0 2.0 9.1 0.0 0.0 0.3 4.5 11.2 0.6 0.0 1.7 5.4 0.1 3.1 0.1 5.6 52.4 9.9 36.5 0.1 0.0 14.6 0.0 0.1 0.1 0.5 0.0 0.0 0.2 14.9 0.0 13.5 0.0 0.0 18.5 0.0 0.1 1.9 10.2 0.5 0.1 1.5 0.1 36.4 0.0 0.0 39.3 27.5 5.1 0.6 4.1 7.6 47.2 0.3 1.4 9.9 0.1 0.0 0.7 8.1 0.4 0.2 0.0 0.0 0.0 33.6 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 17.7 17.1 20.8 29.5 12.9 12.2 17.2 13.9 12.3 19.7 12.9 40.5 44.8 6.9 149.5 0.1 5.6 6.6 18.3 12.0 1.6 1.6 2.5 8.5 30.0 13.7 20.2 2.1 49.2 0.4 0.8 15.6 19.9 2.2 1.9 0.4 40.6 0.0 0.0 104.4 4.0 3.5 5.4 0.0 1.3 1.3 16.7 18.5 2.6 2.6 0.0 156.3 0.4 8.2 0.8 1.1 1.4 1.5 0.4 1.8 79.6 0.0 43.1 0.0 8.5 10.5 7.3 0.2 3.0 0.2 13.4 0.0 40.8 14.3 2.1 13.1 15.1 7.4 0.6 1.1 1.8 5.4 15.5 0.3 46.7 1.1 1.9 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.5;lung: 10.2;stomach 1: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Distal enterocytes: 48.3;Intestinal goblet cells: 75.5;Pancreatic endocrine cells: 53.5;Prostatic glandular cells: 40.1;Urothelial cells: 115.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 45.3;BJ: 29.8;BJ hTERT+: 53.5;fHDF/TERT166: 64.5;HaCaT: 51.8;K-562: 30.7;LHCN-M2: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.1 0.0 0.0 0.7 0.0 0.6 1.1 4.0 0.3 1.1 5.2 10.6 2.2 0.1 0.1 4.5 0.0 2.7 0.4 0.4 0.0 0.0 0.0 10.2 0.0 0.1 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.7 13.5 0.1 8.2 0.1 0.0 0.3 4.1 0.4 0.0 0.1 12.8 0.1 0.1 0.1 0.1 0.1 1.7 4.5 4.6 0.2 45.3 4.8 0.0 0.0 2.0 17.0 0.0 29.8 53.5 0.5 1.1 1.9 24.4 0.0 0.1 64.5 0.0 51.8 0.9 10.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 0.2 0.0 0.9 0.0 0.0 0.0 30.7 0.0 52.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 25.4 0.3 0.6 0.1 0.0 0.1 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.1 157.0 36.1 0.0 0.1 0.8 13.3 20.2 6.2 0.0 0.5 2.8 0.5 2.8 32.9 0.0 0.0 0.0 0.2 48.3 0.0 1.2 6.9 1.2 0.0 0.6 2.4 5.2 0.8 3.2 0.0 2.1 35.7 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 75.5 6.1 0.0 0.7 0.5 0.0 0.3 3.6 0.0 1.6 0.0 0.0 0.0 0.1 53.5 26.4 0.0 1.4 40.1 3.1 0.2 10.0 0.0 0.0 0.5 1.2 2.6 0.5 4.5 0.1 0.0 0.3 0.0 22.7 115.1 GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 27580.7;tongue: 18892.5" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 10357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: AB_641107, CAB016392: AB_627678, CAB079968: , HPA040067: AB_10965903, HPA061280: AB_2684463" "unprognostic (3.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.58e-2)" "unprognostic (4.20e-1)" "unprognostic (9.73e-3)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.89e-3)" "unprognostic (2.86e-1)" "unprognostic (2.06e-2)" "unprognostic (9.50e-3)" "unprognostic (4.52e-1)" "prognostic unfavorable (6.25e-10)" "unprognostic (2.33e-1)" "unprognostic (4.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.26e-2)" 1219.9 1815.8 2605.9 1191.3 2589.5 4608.5 1042.3 2869.0 3067.8 1163.8 2419.2 1720.0 1480.8 1080.9 769.9 2973.8 1042.8 1161.3 5572.8 2630.1 2880.0 2323.2 2557.9 1137.9 1388.3 2845.2 2861.3 1087.0 652.0 1616.0 1338.7 1190.6 2828.4 1241.0 1586.6 2386.8 1835.8 1238.7 27580.7 1775.5 1457.5 1424.4 2670.8 1208.5 1215.5 693.0 2985.1 1570.9 1022.1 18892.5 1861.0 1889.0 1672.9 2741.6 6063.0 10247.9 3109.5 4709.2 3026.2 5018.7 6516.0 4716.2 7218.1 7172.8 7491.2 7211.3 4091.6 7540.8 878.2 5947.4 4904.2 3359.8 3372.7 10829.1 5432.4 6263.1 3229.5 4224.9 5857.5 6279.2 3890.9 6710.2 3046.1 4089.0 3521.7 6553.0 7609.7 15565.8 7762.7 5052.4 2215.9 1484.1 8670.0 11849.8 7303.1 3247.3 10995.7 7254.7 3950.7 5849.8 5505.7 3512.8 7909.6 7115.9 2088.3 3331.0 4243.1 10206.4 5984.0 8874.7 1657.2 4311.2 4794.3 5049.0 5907.2 2717.1 7931.5 3178.4 2544.6 9374.4 10632.2 4050.5 8040.5 2575.4 4295.8 737.9 1325.8 2011.2 1171.4 1046.9 1364.8 1333.1 3253.6 652.5 757.6 886.9 1981.4 1227.8 1900.6 474.6 2126.1 6812.0 2605.9 2589.5 2869.0 3067.8 2630.1 2880.0 2845.2 2861.3 2828.4 2670.8 2985.1 2741.6 1036.7 237.2 259.5 228.2 1086.9 1818.8 2223.4 7367.5 4070.9 1157.6 1794.6 3689.2 40.4 1263.9 2213.7 1022.5 417.0 4237.7 1032.7 2579.6 3463.0 5198.9 759.8 770.1 702.4 1597.4 1324.3 1180.6 112.1 3794.5 10357.8 1127.1 1068.8 1021.8 562.3 2063.7 1242.9 1742.3 3895.3 2348.7 145.8 2351.2 2543.1 2586.7 2494.4 2257.7 889.4 2134.0 4220.8 86.2 3422.3 6177.9 1045.4 98.5 196.2 5681.8 3001.4 1026.9 2668.2 1714.0 5714.0 7286.7 864.3 1435.2 1150.4 1744.7 2827.8 429.9 476.2 3605.2 1600.7 4694.0 1514.9 1839.0 3140.9 2882.4 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 206.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.9;Cardiomyocytes: 33.8;Endothelial cells: 12.1;Fibroblasts: 14.5;Hofbauer cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.6;intermediate monocyte: 28.8;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.6" "Cell line enhanced" "Detected in many" "ASC diff: 77.0;ASC TERT1: 143.3;HSkMC: 166.4;HUVEC TERT2: 193.3;WM-115: 74.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA 13000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA007227: AB_1847689" "unprognostic (4.87e-2)" "unprognostic (7.79e-2)" "unprognostic (6.60e-3)" "unprognostic (9.42e-3)" "unprognostic (2.37e-2)" "unprognostic (7.47e-2)" "unprognostic (2.13e-2)" "unprognostic (7.49e-2)" "unprognostic (9.20e-3)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-3)" "unprognostic (3.74e-3)" "unprognostic (3.85e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" 73.9 206.2 29.0 39.8 29.2 2.8 47.3 21.8 23.3 47.0 11.9 23.4 13.3 77.7 21.8 17.2 19.4 37.1 77.9 28.7 29.6 9.5 8.6 14.1 11.2 51.7 33.0 140.3 14.2 11.5 2.8 29.0 26.9 23.6 23.3 0.8 23.6 30.0 12.4 7.3 18.5 70.2 34.1 20.8 11.8 10.4 35.5 5.7 17.7 16.7 6.8 43.2 9.2 33.0 12.5 9.9 6.1 1.1 77.0 143.3 11.4 3.1 2.4 0.6 3.7 13.3 4.9 0.1 0.3 5.0 5.1 0.2 70.7 18.9 1.8 0.1 0.2 1.0 0.0 37.0 51.4 0.6 0.3 166.4 4.6 24.2 2.6 8.0 193.3 0.0 13.0 0.0 35.7 0.8 0.0 0.2 0.4 43.4 0.2 0.1 0.5 0.2 0.0 27.5 0.4 0.1 0.0 27.8 8.2 33.4 5.4 0.3 9.3 16.0 17.1 9.6 6.1 0.0 0.1 44.8 2.5 0.3 74.3 0.1 50.6 0.0 0.1 28.8 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.7 0.1 14.0 0.6 0.0 17.8 29.0 29.2 21.8 23.3 28.7 29.6 51.7 33.0 26.9 34.1 35.5 33.0 22.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 1.2 14.5 0.0 0.0 0.0 0.0 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Rod photoreceptor cells: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: AB_1849530" "unprognostic (3.34e-2)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "unprognostic (3.99e-2)" "unprognostic (8.69e-2)" "prognostic favorable (6.00e-4)" "unprognostic (9.01e-3)" "prognostic favorable (1.24e-11)" "unprognostic (7.62e-3)" "unprognostic (2.94e-1)" "unprognostic (7.69e-2)" "prognostic favorable (6.60e-4)" 39.3 45.7 48.5 23.2 47.5 16.3 39.9 52.8 53.7 46.4 63.3 83.5 54.2 44.6 26.9 36.3 44.2 26.3 83.3 47.2 54.2 84.4 65.9 54.1 24.6 54.1 56.2 39.8 54.1 37.2 65.5 24.7 56.1 60.2 41.0 71.1 50.0 27.7 75.8 39.3 89.7 22.9 45.1 58.5 63.9 30.8 58.9 18.3 61.7 43.7 21.6 53.0 40.9 48.7 18.1 29.3 39.6 38.4 18.8 11.4 40.0 24.1 18.8 23.9 25.0 32.8 14.1 19.3 17.1 14.7 51.5 18.4 38.2 16.2 12.0 27.5 26.2 20.8 87.8 35.6 20.8 31.2 49.4 19.8 29.8 20.3 21.1 57.9 63.4 18.9 20.7 36.0 22.6 18.0 8.5 32.0 41.2 36.6 45.7 15.5 16.0 16.3 33.3 41.9 32.2 43.0 13.5 33.3 24.5 48.1 22.8 27.8 44.6 25.8 30.9 22.4 29.9 24.2 16.5 16.0 32.3 11.3 20.5 11.1 2.9 2.0 3.8 3.9 2.5 3.7 3.7 4.7 2.8 4.7 2.2 1.9 3.2 2.4 2.5 4.4 2.8 2.2 48.5 47.5 52.8 53.7 47.2 54.2 54.1 56.2 56.1 45.1 58.9 48.7 12.7 12.8 8.0 45.1 11.2 7.4 18.2 9.4 6.2 77.5 15.0 10.8 13.7 17.2 14.5 27.6 114.7 11.1 16.6 71.7 21.5 10.5 14.1 10.0 8.1 16.0 35.8 17.2 23.5 12.0 10.2 8.0 46.4 13.8 14.0 18.7 30.7 20.1 9.2 52.2 26.4 35.8 16.2 12.8 10.7 24.3 12.5 10.7 12.4 8.4 13.3 16.2 12.3 18.1 20.2 15.1 57.6 9.8 11.7 15.8 87.4 17.8 17.9 102.9 13.1 12.2 12.2 9.2 5.7 8.8 9.9 22.2 9.4 11.3 41.4 26.3 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GCC1 "FLJ22035, GCC1P, GCC88, MGC20706" ENSG00000179562 "GRIP and coiled-coil domain containing 1" Q96CN9 7 127580628-127593611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 102.7;Late spermatids: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019369, HPA021323" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA019369: AB_1849552, HPA021323: AB_1849554" "unprognostic (1.09e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-1)" "unprognostic (9.51e-2)" "unprognostic (1.07e-1)" "unprognostic (7.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.54e-2)" "unprognostic (1.83e-1)" "unprognostic (5.08e-2)" "unprognostic (4.81e-2)" "unprognostic (4.50e-3)" "unprognostic (1.17e-3)" "unprognostic (4.17e-3)" "unprognostic (1.22e-1)" "unprognostic (8.65e-2)" "unprognostic (9.96e-2)" 6.6 6.6 5.4 7.8 6.3 13.5 9.2 6.4 5.7 7.0 6.2 6.9 6.5 6.1 6.5 7.0 5.9 6.3 4.8 5.2 5.9 6.2 10.6 6.9 8.6 6.3 6.3 8.0 6.9 9.4 4.5 7.5 6.1 7.3 6.2 3.6 8.2 6.7 6.6 7.8 6.5 5.1 6.2 8.3 7.7 11.0 6.1 8.3 7.7 6.7 9.9 7.1 4.7 7.2 15.7 20.8 9.0 19.5 19.7 13.5 12.4 13.4 15.5 13.2 16.5 17.5 10.5 14.4 8.0 12.6 29.7 17.0 13.1 14.7 14.1 20.3 11.9 10.6 11.4 9.2 29.2 18.5 16.9 12.7 39.7 14.1 27.8 12.4 12.6 14.2 17.6 16.1 15.0 15.6 18.0 16.0 18.8 17.2 16.1 12.7 9.8 16.5 11.4 12.0 14.2 20.6 14.4 67.9 27.5 16.1 11.6 13.2 16.4 19.5 6.3 17.0 15.6 43.6 20.6 9.1 19.3 18.6 20.2 5.3 7.1 13.2 7.1 6.9 9.1 6.6 6.4 7.0 6.6 6.3 5.1 5.2 13.1 8.7 8.2 3.8 6.5 8.1 5.4 6.3 6.4 5.7 5.2 5.9 6.3 6.3 6.1 6.2 6.1 7.2 4.8 12.8 7.7 0.0 9.6 10.6 5.0 2.7 12.0 4.1 11.5 6.1 3.6 4.3 3.7 3.7 4.2 7.2 7.3 10.0 5.9 5.1 102.7 4.3 5.5 6.7 7.2 8.2 0.0 6.4 4.6 5.0 8.6 6.8 1.3 5.9 5.0 7.4 5.2 11.8 0.0 8.2 2.0 10.1 8.3 131.7 5.3 7.6 12.4 0.0 6.9 4.9 5.2 0.0 0.0 5.9 6.6 3.8 6.3 5.4 6.0 4.5 2.4 5.9 6.6 5.9 6.5 7.8 4.6 6.3 10.4 10.4 8.8 5.8 5.8 5.4 GCH1 "DYT14, DYT5, DYT5a, GCH, GTPCH1" ENSG00000131979 "GTP cyclohydrolase 1" P30793 14 54842008-54902826 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" "Allosteric enzyme, Hydrolase" "Disease variant, Dystonia, Parkinsonism, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;liver: 36.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 212.5;Hepatocytes: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 11.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.5;Daudi: 25.0;JURKAT: 23.0;SH-SY5Y: 50.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 12.7" HPA028612 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028612: AB_10602135" "unprognostic (3.77e-2)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (2.39e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.75e-1)" "unprognostic (3.97e-1)" "prognostic favorable (8.69e-4)" "prognostic favorable (1.41e-4)" "unprognostic (1.23e-1)" "unprognostic (1.96e-2)" "unprognostic (7.22e-3)" "unprognostic (1.76e-2)" "unprognostic (2.23e-1)" "prognostic favorable (6.67e-4)" 2.4 6.0 2.1 8.1 3.0 31.4 1.8 1.1 2.0 0.4 1.5 2.4 9.4 0.4 0.2 3.5 1.2 0.4 1.9 1.9 4.8 4.6 36.7 4.1 7.0 3.5 16.1 0.5 2.6 0.9 1.8 0.3 8.4 1.5 2.4 0.1 1.7 1.0 0.4 2.2 7.5 1.1 2.4 6.9 2.8 1.2 7.8 3.8 0.8 0.2 2.0 3.3 1.4 2.0 4.7 0.6 1.3 7.1 0.0 0.0 23.5 0.0 2.0 2.4 2.9 1.4 1.0 25.0 6.9 0.2 5.8 4.0 4.9 1.5 0.1 10.9 5.2 0.6 0.3 3.1 8.4 0.0 1.9 0.3 0.7 1.2 0.1 0.0 0.7 23.0 2.8 0.0 0.0 5.0 15.1 0.3 0.4 6.5 8.2 9.6 2.8 0.0 2.9 1.6 11.6 50.9 3.3 2.4 1.6 0.4 2.9 1.5 0.3 0.1 4.0 9.9 3.8 10.5 8.4 7.8 3.1 8.4 0.0 0.0 2.6 0.2 2.8 5.3 2.1 0.7 1.0 1.5 2.8 1.9 2.5 1.3 0.3 1.8 11.1 0.1 2.1 1.2 2.1 3.0 1.1 2.0 1.9 4.8 3.5 16.1 8.4 2.4 7.8 2.0 19.2 3.2 4.8 0.7 33.4 74.6 30.9 23.6 17.6 0.0 19.4 13.2 6.5 4.3 13.6 5.5 2.1 1.9 50.9 21.8 7.9 8.7 0.5 16.8 5.8 19.8 212.5 10.1 3.8 9.4 44.3 15.3 43.8 29.3 0.0 0.3 6.8 94.6 6.1 0.0 5.9 22.7 4.1 28.0 33.3 0.6 0.3 55.8 10.6 15.9 29.5 0.7 29.9 0.5 0.8 11.0 13.6 4.9 14.4 20.5 17.1 48.6 6.9 0.4 0.0 12.5 7.5 2.2 6.7 20.8 76.1 4.2 41.8 11.9 12.2 39.0 GCKR ENSG00000084734 "Glucokinase regulator" 2 27496839-27523684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 136.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 96.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.4;Hep G2: 20.7;HUVEC TERT2: 6.4;TIME: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034098, HPA045855, HPA052227" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "CAB034098: AB_2247323, HPA045855: , HPA052227: " "unprognostic (3.31e-1)" "unprognostic (2.11e-3)" "unprognostic (2.27e-1)" "unprognostic (6.97e-2)" "unprognostic (1.68e-2)" "unprognostic (5.70e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (1.02e-7)" "unprognostic (6.51e-2)" "unprognostic (1.18e-1)" "unprognostic (9.27e-3)" "unprognostic (1.50e-2)" 0.8 7.1 0.8 0.2 1.3 0.9 0.6 4.7 1.6 0.5 1.4 0.1 0.7 0.5 0.6 1.5 0.2 2.3 0.4 1.0 1.3 0.5 136.4 0.2 0.6 1.7 1.2 5.8 1.8 0.2 0.4 0.2 1.6 0.5 0.3 0.9 0.4 0.2 0.3 0.8 0.2 0.3 0.3 1.6 6.5 2.7 1.1 0.2 0.1 0.1 0.3 0.3 0.4 1.4 0.2 0.4 0.4 0.2 0.3 0.2 0.1 0.0 0.1 0.3 0.0 0.4 0.1 0.2 0.5 0.7 0.2 0.2 0.2 0.0 0.0 0.1 0.0 13.4 0.7 20.7 0.8 0.0 0.4 0.3 1.0 0.5 0.1 2.2 6.4 0.1 0.0 0.2 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.5 0.2 4.2 0.1 0.3 0.6 0.2 0.4 0.1 0.2 1.2 0.1 0.2 0.8 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.4 0.3 0.0 0.1 0.0 0.2 0.8 1.3 4.7 1.6 1.0 1.3 1.7 1.2 1.6 0.3 1.1 1.4 0.3 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 7.9 0.1 0.6 0.6 0.0 0.0 2.0 10.4 0.0 0.2 18.3 0.1 0.0 0.1 0.7 96.5 0.1 0.0 1.6 0.0 0.0 2.1 0.0 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 13.7 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 1.7 0.2 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 220.7;Urothelial cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 205.4;Hep G2: 178.2;OE19: 287.5;RT4: 189.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favorable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.30e-2)" 26.7 18.3 18.5 16.6 24.9 37.8 27.2 18.1 23.3 9.5 14.1 22.8 41.9 19.2 10.8 37.0 62.9 32.1 16.4 16.8 18.9 34.1 152.1 10.9 26.2 18.4 19.7 8.5 15.9 18.3 4.8 9.1 20.4 26.9 26.0 14.4 13.1 15.8 11.4 18.8 32.2 16.0 18.2 39.1 32.9 11.3 22.5 13.7 30.0 14.5 24.0 63.7 14.5 36.0 31.3 205.4 16.5 39.1 19.4 8.6 22.1 15.5 24.9 11.4 13.3 30.5 70.7 59.1 28.7 14.1 86.9 43.3 50.7 112.5 15.3 46.9 31.4 39.6 38.3 178.2 22.1 52.8 23.5 13.5 46.6 12.8 56.8 15.0 17.7 50.9 22.4 18.2 5.6 32.9 45.5 20.9 30.6 287.5 19.2 14.9 10.2 52.1 37.0 189.8 47.5 23.3 25.9 40.9 27.8 23.8 28.2 24.6 24.6 10.2 35.5 26.0 23.4 24.1 39.9 34.0 25.6 37.0 17.5 1.2 0.5 0.3 0.5 0.9 0.4 0.8 0.5 1.1 2.3 0.5 0.3 0.6 0.2 4.2 1.0 1.6 0.9 0.3 18.5 24.9 18.1 23.3 16.8 18.9 18.4 19.7 20.4 18.2 22.5 36.0 17.1 0.0 2.4 36.9 12.7 34.8 61.6 56.6 47.3 14.4 23.7 13.6 20.9 38.6 47.4 0.0 25.0 6.4 22.9 22.1 11.7 14.6 2.2 34.8 14.9 14.1 220.7 113.2 22.4 12.8 8.6 13.6 43.8 69.8 2.5 50.9 10.4 118.5 22.7 8.4 30.4 19.4 40.7 87.2 10.9 1.5 6.5 32.1 8.8 24.4 10.6 12.5 17.5 30.2 84.1 15.9 13.2 9.4 10.4 88.3 18.2 27.1 66.5 5.0 13.1 14.0 13.5 3.1 9.2 72.6 24.9 7.8 14.9 26.6 14.8 144.8 GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 207.9;Erythroid cells: 301.9;Prostatic glandular cells: 762.3;Urothelial cells: 374.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: AB_2107835, CAB040554: , HPA023696: AB_1849560" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (8.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (4.64e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (3.53e-1)" "unprognostic (3.51e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" 12.2 13.1 5.4 6.6 4.7 15.0 6.6 5.1 5.4 4.5 5.6 6.2 19.2 3.6 4.0 6.6 14.3 14.1 4.7 4.7 7.5 11.3 48.5 5.9 4.6 6.4 6.9 2.8 7.7 6.7 3.4 10.3 7.1 5.6 5.5 3.6 4.5 5.9 16.0 3.0 12.7 3.6 5.1 6.8 5.7 3.2 5.7 5.0 16.8 11.8 10.1 6.9 3.7 6.1 37.7 58.6 6.4 12.6 20.9 13.0 24.4 43.7 27.3 32.8 24.3 9.9 21.7 14.2 84.8 28.8 106.7 37.3 9.6 18.0 26.2 38.6 12.7 98.9 37.4 42.8 39.1 36.8 15.2 16.1 6.7 67.0 10.7 13.2 36.4 16.0 40.0 20.5 24.0 7.3 26.8 8.5 21.5 36.0 27.4 12.3 19.0 20.9 23.6 43.4 14.8 6.1 41.3 32.2 15.4 71.8 7.2 22.7 38.4 34.1 20.1 64.5 66.7 18.1 25.0 14.7 28.2 20.4 12.2 2.1 0.3 0.7 2.6 0.2 1.5 1.3 2.5 3.4 0.3 2.0 1.5 1.6 1.5 2.3 0.3 1.0 0.7 0.7 5.4 4.7 5.1 5.4 4.7 7.5 6.4 6.9 7.1 5.1 5.7 6.1 28.7 41.7 19.1 16.0 14.6 11.5 207.9 33.2 24.5 24.8 24.2 34.2 16.4 61.5 29.0 29.5 6.2 63.5 39.3 21.7 25.4 25.1 3.9 66.3 27.6 55.5 52.5 301.9 32.0 12.3 19.6 44.5 15.8 50.1 19.7 17.3 31.4 102.4 19.9 33.7 30.7 19.9 22.4 20.7 51.4 4.0 21.5 32.0 8.8 15.0 9.3 21.2 34.0 11.1 11.6 24.2 8.0 12.4 21.6 762.3 47.2 65.1 64.3 13.1 0.0 48.4 37.1 32.0 36.7 33.5 9.2 45.0 34.1 26.5 17.8 374.9 GCNT7 "C20orf105, dJ1153D9.2" ENSG00000124091 "Glucosaminyl (N-acetyl) transferase family member 7" Q6ZNI0 20 56491492-56525925 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "bone marrow: 4.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Excitatory neurons: 1.4;Inhibitory neurons: 1.2;Late spermatids: 1.0;Oligodendrocyte precursor cells: 3.0;Oligodendrocytes: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA052617, HPA059403" Uncertain Approved "Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear bodies, Vesicles" Cytosol "HPA052617: AB_2681886, HPA059403: " "unprognostic (3.57e-2)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (1.89e-1)" "unprognostic (3.96e-2)" "unprognostic (9.08e-2)" "unprognostic (3.10e-1)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (2.38e-1)" "unprognostic (9.69e-2)" "unprognostic (2.84e-2)" "unprognostic (2.16e-3)" "unprognostic (1.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.96e-1)" "unprognostic (8.69e-2)" 0.0 0.1 0.1 0.3 0.2 4.4 0.0 0.6 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.9 0.0 0.1 0.2 0.2 0.0 0.1 0.2 0.6 0.2 0.1 0.2 0.3 0.2 0.3 0.1 0.4 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 28.9 25.9 42.9 15.6 46.3 27.8 21.1 42.9 49.9 21.9 40.4 44.9 30.0 20.0 27.5 22.4 16.9 18.4 52.8 45.7 45.5 27.6 25.4 29.3 11.7 44.5 47.7 12.8 28.5 76.8 19.2 20.5 43.3 26.7 41.6 19.8 28.3 30.3 62.9 26.4 27.7 26.5 42.8 13.5 34.3 14.1 48.8 16.8 20.3 64.4 15.3 30.2 16.6 47.4 38.6 46.2 25.0 29.4 115.3 43.3 34.7 38.3 66.9 30.0 37.1 26.6 67.4 29.2 48.1 57.2 32.8 31.8 35.2 46.6 36.9 31.7 52.8 24.2 41.4 57.2 69.1 32.7 21.5 44.9 73.1 32.2 37.4 54.5 40.6 36.3 13.7 29.1 33.2 70.3 28.3 29.1 29.1 59.9 34.2 40.2 45.7 41.7 72.9 59.7 28.9 25.8 37.0 44.5 37.9 38.5 45.8 37.8 42.7 25.3 22.3 33.9 24.6 27.0 27.4 19.9 38.5 47.2 23.1 52.0 19.3 11.2 8.9 17.7 11.5 7.2 10.4 10.4 12.4 6.1 5.5 8.5 34.0 6.6 22.7 7.5 12.7 8.2 42.9 46.3 42.9 49.9 45.7 45.5 44.5 47.7 43.3 42.8 48.8 47.4 12.2 38.5 86.8 7.2 18.9 23.5 30.3 56.2 22.8 15.4 38.3 22.4 66.8 34.3 56.0 9.2 27.1 80.4 23.2 123.1 23.5 97.0 35.1 26.9 23.8 17.7 33.5 100.8 12.0 163.9 78.6 27.3 24.5 21.5 3.8 36.4 20.7 23.9 60.8 32.0 15.9 57.5 61.1 48.2 22.9 61.2 28.6 32.3 24.9 8.4 38.2 22.3 24.7 9.5 25.0 77.4 97.6 38.0 19.6 100.5 101.7 45.9 39.7 29.6 13.1 16.7 24.9 87.1 59.6 31.9 29.5 270.4 22.0 45.9 85.3 79.2 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 447.4" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 32.1;MCF7: 50.6;OE19: 53.3;SK-BR-3: 165.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" 7.1 2.4 6.1 6.0 6.1 1.8 5.4 6.8 11.4 18.7 5.9 25.9 8.4 5.3 9.3 45.6 5.7 2.5 5.2 6.0 6.1 17.9 2.1 6.4 4.2 7.5 6.1 6.8 2.2 0.4 4.8 11.4 8.0 5.7 17.2 6.5 9.0 2.2 2.1 11.0 10.2 5.2 6.3 9.0 18.8 1.8 6.1 4.1 4.7 0.9 20.9 5.4 19.1 6.8 21.8 0.3 5.2 1.5 1.6 5.5 5.5 0.6 1.3 1.8 1.7 1.0 15.2 0.6 2.9 1.5 0.6 1.8 1.6 0.5 1.8 2.5 4.0 0.2 1.0 32.1 1.0 0.7 1.3 0.2 1.6 4.5 0.3 4.1 5.1 4.2 1.0 2.3 2.2 50.6 1.5 2.0 2.6 53.3 0.6 6.3 1.4 7.1 2.6 7.4 1.1 2.2 0.2 165.0 0.5 1.6 3.0 2.7 2.7 0.9 1.1 1.9 1.8 2.7 0.9 1.5 4.2 2.7 0.7 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 0.0 6.1 6.1 6.8 11.4 6.0 6.1 7.5 6.1 8.0 6.3 6.1 6.8 5.9 6.4 1.1 1.6 1.0 1.3 0.9 4.4 1.2 1.6 4.1 3.0 1.5 0.0 22.2 5.5 0.0 24.2 1.2 98.2 5.9 0.9 67.8 2.6 3.8 4.3 3.5 0.0 0.6 1.3 71.9 2.1 30.1 4.1 0.0 2.0 3.9 0.3 3.1 1.7 0.8 34.2 6.1 1.9 1.0 447.4 3.4 1.4 1.8 1.9 1.2 0.6 0.0 1.5 1.2 19.2 36.7 3.0 0.1 1.1 46.0 100.6 9.0 1.7 6.6 0.6 2.7 1.4 1.3 5.1 2.0 9.3 1.9 1.3 13.9 4.8 GEMIN2 SIP1 ENSG00000092208 "Gem nuclear organelle associated protein 2" O14893 14 39114223-39136973 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 45.8;Late spermatids: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015426, HPA046570, HPA057114" Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Nucleoli "CAB015426: AB_629517, HPA046570: AB_2679703, HPA057114: AB_2683340" "unprognostic (4.53e-1)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (5.07e-3)" "unprognostic (1.04e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.88e-6)" "unprognostic (8.62e-3)" "unprognostic (3.05e-2)" "unprognostic (1.99e-3)" "unprognostic (3.08e-1)" "unprognostic (3.03e-1)" "unprognostic (4.53e-3)" "unprognostic (1.52e-1)" "unprognostic (1.58e-1)" "unprognostic (3.95e-1)" "unprognostic (6.78e-2)" 6.1 4.3 6.1 4.5 6.3 10.3 7.9 10.2 7.9 5.9 4.6 6.0 6.7 5.4 7.2 5.7 5.9 4.2 7.7 5.7 3.9 6.1 5.6 4.8 8.8 3.6 2.6 5.9 4.7 3.7 4.6 5.6 3.6 4.8 6.1 4.7 4.3 4.5 12.1 6.3 4.7 7.7 1.1 5.2 5.1 8.3 3.4 9.1 5.5 7.9 7.8 6.2 5.5 6.2 23.6 34.5 33.3 23.7 11.3 12.6 17.0 11.5 9.0 30.3 30.0 30.7 27.9 36.0 23.4 9.8 11.0 17.5 45.6 18.7 31.5 17.6 26.7 21.5 18.1 76.8 23.9 32.6 12.8 7.3 17.6 18.8 27.5 8.7 26.6 31.4 25.2 25.6 17.3 48.9 36.3 31.2 23.6 29.7 38.3 32.8 36.4 22.6 17.5 15.6 32.2 6.2 24.5 17.7 12.4 18.4 41.5 14.0 11.2 12.7 20.0 13.3 18.6 26.8 44.2 54.1 6.6 34.0 19.6 10.8 12.0 9.9 13.5 13.1 9.8 15.3 12.3 13.5 16.2 15.8 13.5 14.4 3.1 11.9 11.5 16.1 11.8 9.2 6.1 6.3 10.2 7.9 5.7 3.9 3.6 2.6 3.6 1.1 3.4 6.2 11.6 6.4 3.7 4.9 10.3 8.5 8.1 20.9 8.0 5.9 7.3 12.1 6.0 5.7 11.4 5.5 10.4 12.9 7.0 2.2 11.7 10.8 45.8 11.2 11.3 10.6 3.6 17.2 7.4 6.4 18.9 12.5 2.6 7.5 5.7 11.7 9.7 6.6 11.4 5.0 6.2 7.1 14.2 10.6 7.3 41.1 9.0 6.3 7.2 4.7 9.4 8.1 9.2 4.0 7.4 6.9 2.5 9.8 9.4 8.0 3.1 14.7 15.5 6.9 6.6 8.3 8.1 25.9 15.4 11.3 8.0 3.8 9.1 11.6 9.3 4.8 GET4 "C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35" ENSG00000239857 "Guided entry of tail-anchored proteins factor 4" Q7L5D6 7 876554-896436 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 36.7;Oligodendrocytes: 15.8;Plasma cells: 37.2;Squamous epithelial cells: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019765 Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome,Cytosol" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nucleoli, Mitotic chromosome" "HPA019765: AB_1845750" "unprognostic (2.80e-2)" "unprognostic (2.40e-2)" "unprognostic (2.10e-2)" "unprognostic (9.66e-4)" "unprognostic (9.86e-2)" "unprognostic (8.64e-2)" "unprognostic (4.10e-2)" "unprognostic (1.74e-1)" "unprognostic (2.59e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" "unprognostic (7.65e-2)" "unprognostic (8.18e-2)" "unprognostic (1.26e-1)" "unprognostic (5.93e-2)" "unprognostic (9.47e-2)" 25.0 98.0 28.9 12.5 33.7 31.6 26.8 29.7 37.0 28.1 19.1 33.5 20.8 25.5 21.1 43.7 32.1 11.4 33.1 28.8 31.1 68.8 98.4 25.5 15.8 36.1 33.4 34.3 46.1 13.7 70.7 20.5 36.0 37.8 8.8 16.4 28.8 12.3 56.3 46.9 33.6 7.7 29.1 37.5 41.5 79.0 34.0 14.4 34.3 21.9 10.4 31.3 28.9 45.6 78.8 38.1 25.8 38.4 13.2 9.1 81.7 21.2 14.9 26.5 26.6 103.4 95.1 28.5 21.7 12.4 73.7 48.7 29.3 23.3 11.5 11.6 50.9 15.8 31.5 59.5 29.1 27.1 28.1 13.8 27.6 23.4 15.1 19.9 21.1 32.5 103.6 25.7 15.2 59.7 20.8 65.2 93.3 46.1 56.0 43.0 4.5 30.8 23.8 45.4 46.7 50.5 19.5 71.2 32.2 31.5 54.2 47.8 21.4 19.6 43.6 45.7 29.5 38.5 25.9 37.5 20.1 46.2 50.3 22.3 28.5 32.4 23.9 27.6 23.3 24.3 26.4 24.1 29.4 24.5 25.2 27.0 21.9 27.7 35.3 33.3 26.9 24.8 28.9 33.7 29.7 37.0 28.8 31.1 36.1 33.4 36.0 29.1 34.0 45.6 0.3 0.0 3.1 14.7 10.6 1.0 0.3 0.2 14.8 0.8 1.1 0.9 0.6 0.0 2.2 0.0 4.2 1.1 0.7 2.3 0.0 0.9 4.0 2.0 1.1 1.5 0.0 9.2 9.1 0.7 0.7 3.8 36.7 2.8 1.3 1.2 0.0 0.4 0.6 8.4 9.1 2.8 0.0 0.6 0.8 2.7 0.0 6.1 0.0 4.7 0.5 0.2 0.0 10.1 15.8 0.8 1.0 0.0 37.2 0.4 3.6 1.1 2.1 1.4 0.0 0.8 1.8 0.6 1.1 23.5 1.0 1.6 9.9 0.8 1.7 0.8 GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.6 18.1 9.7 10.2 10.5 15.0 14.1 10.2 14.5 10.7 16.1 13.9 9.3 11.1 17.4 11.9 23.4 9.0 33.3 10.8 10.7 23.3 34.0 9.0 12.2 9.5 9.1 11.4 10.0 30.4 10.7 13.5 10.0 13.0 15.8 16.8 13.4 11.2 30.6 11.3 10.8 10.8 9.4 8.5 17.9 15.8 10.2 17.2 13.1 38.5 15.5 12.9 7.0 11.1 39.5 34.3 27.2 52.2 20.3 27.1 28.2 41.5 24.7 41.5 44.1 36.4 24.9 39.7 44.9 21.9 65.7 32.1 55.0 59.6 54.8 34.8 35.5 22.9 31.7 27.0 27.1 23.6 26.0 32.1 26.3 33.6 40.5 29.8 30.3 39.4 40.7 32.9 48.5 23.3 32.1 15.1 11.4 14.8 29.7 41.1 43.5 49.3 32.0 24.7 46.6 24.8 46.3 38.1 44.3 30.1 33.0 44.0 24.0 16.2 27.8 20.5 27.2 19.0 38.3 40.1 24.1 34.2 24.6 22.8 6.9 9.2 6.7 7.2 6.6 8.3 5.5 7.5 6.7 7.2 7.5 7.3 3.5 16.0 11.8 4.4 7.0 5.2 9.7 10.5 10.2 14.5 10.8 10.7 9.5 9.1 10.0 9.4 10.2 11.1 6.4 12.8 12.9 19.9 8.5 6.0 7.1 13.0 8.6 9.1 7.7 6.9 11.0 7.2 12.5 7.3 6.2 20.1 7.5 8.9 21.5 9.5 11.5 42.4 9.2 6.4 5.4 17.9 35.7 5.3 15.9 6.3 15.3 13.7 2.5 10.4 5.3 22.4 9.9 16.8 34.1 9.7 30.5 8.5 2.4 2.6 7.2 6.8 8.8 13.1 17.9 13.0 7.2 34.2 29.1 9.8 9.9 7.5 11.4 4.6 8.5 11.2 61.5 9.6 0.0 5.6 7.8 15.2 11.7 10.0 7.0 16.0 7.3 11.1 10.0 7.5 GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cardiomyocytes: 108.2;Excitatory neurons: 133.2;Inhibitory neurons: 106.2;NK-cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEL: 30.5;HMC-1: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" 10.5 2.0 14.3 2.8 21.6 12.7 9.6 11.2 26.1 5.0 0.0 6.2 1.8 3.6 0.8 8.6 4.4 4.3 16.7 24.5 3.7 2.3 7.2 9.7 4.3 3.0 1.5 1.5 1.5 1.7 3.5 3.9 2.3 4.0 2.8 2.1 3.6 1.4 12.0 5.5 6.5 4.9 0.6 8.8 7.9 0.6 2.5 3.0 2.7 9.7 4.2 6.2 5.8 16.9 12.5 1.3 1.0 2.1 1.7 1.8 1.3 1.0 0.5 0.7 0.4 0.4 0.9 16.8 16.6 1.2 1.0 10.9 3.4 5.4 0.7 1.2 6.0 30.5 7.2 6.6 2.4 9.0 46.3 0.9 4.1 1.6 4.5 2.6 9.5 4.5 0.9 1.5 1.3 4.1 2.0 5.2 1.8 4.3 3.3 6.9 2.1 8.8 0.6 2.4 5.5 1.0 4.0 0.7 4.0 2.1 0.9 0.9 12.2 1.6 3.2 3.5 5.6 13.4 8.3 19.8 1.4 5.3 0.4 0.2 0.4 15.5 1.5 0.9 0.2 2.7 0.2 0.7 0.2 1.9 0.1 0.5 0.3 13.1 0.9 0.1 0.1 1.0 14.3 21.6 11.2 26.1 24.5 3.7 3.0 1.5 2.3 0.6 2.5 16.9 100.9 0.0 1.8 33.0 14.3 20.3 4.9 14.5 19.9 43.8 7.4 3.7 108.2 10.0 14.4 0.0 0.0 1.5 46.1 18.2 0.0 5.3 0.1 3.8 1.0 49.0 8.4 31.2 133.2 3.1 34.7 9.1 2.0 8.0 4.5 0.2 51.4 19.5 2.5 1.7 106.2 11.2 8.2 15.7 31.3 0.3 2.5 21.4 12.4 42.2 4.7 2.1 142.2 58.8 56.6 30.5 31.7 1.2 14.5 3.1 10.6 0.3 13.6 2.7 13.1 19.9 17.5 0.0 3.3 34.6 22.4 0.7 23.4 1.0 4.4 4.7 GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319780-69387250 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 184.2;Intestinal goblet cells: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 93000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center" "HPA047240: " "unprognostic (4.38e-3)" "unprognostic (8.20e-2)" "prognostic favorable (7.13e-5)" "unprognostic (2.97e-1)" "unprognostic (1.32e-1)" "unprognostic (2.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (5.00e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" 31.2 17.9 6.6 21.5 6.5 15.0 22.4 5.5 7.1 37.8 31.5 74.3 38.4 15.6 41.6 16.4 24.3 32.5 24.8 7.0 11.0 21.6 23.1 17.0 10.6 4.9 10.5 12.0 33.7 26.2 18.9 36.0 10.8 36.7 76.6 10.4 42.4 25.9 10.2 6.0 41.2 23.2 5.3 9.5 64.3 46.6 8.0 10.2 91.8 13.9 15.9 21.8 9.2 6.8 46.6 42.7 34.7 20.9 107.7 75.8 73.5 97.1 94.5 44.7 59.3 109.5 50.5 31.7 31.9 92.9 61.4 22.6 47.1 28.6 73.6 38.4 18.4 38.2 25.0 94.5 123.0 27.9 17.9 47.8 132.5 88.7 158.8 55.5 43.4 29.8 34.8 58.3 85.2 30.9 31.3 22.9 37.0 116.7 27.4 28.2 79.1 18.3 70.6 42.0 25.2 11.9 35.2 52.4 93.7 73.5 22.7 17.2 61.8 37.2 62.3 64.6 47.5 39.5 32.2 25.4 65.7 18.3 46.9 9.2 3.5 4.9 7.5 4.3 7.0 6.4 6.5 8.3 4.7 3.6 6.3 6.2 1.2 5.2 5.2 4.4 5.0 4.2 6.6 6.5 5.5 7.1 7.0 11.0 4.9 10.5 10.8 5.3 8.0 6.8 14.6 51.3 49.5 15.7 29.8 28.4 21.6 31.7 26.7 13.7 50.6 16.5 43.1 42.9 54.5 44.1 12.5 28.6 30.3 184.2 17.6 34.1 123.9 54.4 54.1 17.2 75.1 3.8 49.2 89.5 70.3 37.6 110.1 60.0 24.1 19.2 17.9 53.6 17.0 6.7 56.3 244.0 16.2 10.0 31.4 23.7 23.3 16.0 53.4 27.2 28.1 10.6 13.4 42.7 43.8 66.0 83.3 28.2 82.1 72.3 62.5 30.0 89.7 14.0 19.7 21.6 41.8 134.1 45.3 20.3 21.0 34.3 33.4 15.7 135.3 56.3 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GGA1 ENSG00000100083 "Golgi associated, gamma adaptin ear containing, ARF binding protein 1" Q9UJY5 22 37608725-37633564 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 179.3" "Cell type enhanced" "Detected in all" "Late spermatids: 221.2;Spermatocytes: 193.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048280, HPA051016" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA048280: AB_2680338, HPA051016: AB_2681312" "unprognostic (1.64e-1)" "unprognostic (1.42e-2)" "unprognostic (4.08e-1)" "unprognostic (9.23e-3)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.32e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.42e-2)" "unprognostic (1.53e-2)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.16e-3)" 25.0 49.3 35.9 23.3 39.7 37.2 27.3 39.0 42.3 38.0 41.0 35.0 24.3 32.1 21.5 41.1 37.4 20.4 29.5 35.3 35.0 42.4 42.1 33.7 29.1 41.1 37.6 46.3 34.5 33.2 52.7 19.1 38.4 40.0 17.8 22.8 34.9 19.6 43.1 35.7 40.7 16.9 36.1 55.6 34.9 179.3 41.2 26.9 44.7 24.6 21.1 31.6 33.5 45.0 37.4 28.3 32.9 31.1 28.0 23.0 35.4 30.8 25.0 27.0 29.6 23.3 21.8 59.9 20.6 22.9 17.0 35.0 29.4 35.6 24.8 51.0 53.6 24.0 52.3 27.3 28.1 56.1 42.6 28.4 31.3 38.9 24.2 45.1 26.5 30.3 48.0 36.8 27.8 37.7 24.8 64.2 26.2 39.2 28.7 28.5 25.8 25.2 28.8 31.0 30.4 54.0 18.7 39.0 48.9 31.3 42.4 42.0 31.0 36.8 35.2 32.1 24.4 81.1 35.3 62.5 39.9 33.6 30.8 8.1 10.7 6.1 18.0 10.2 22.1 8.3 7.2 23.3 6.7 5.0 5.1 16.5 4.5 11.6 7.9 5.8 8.0 11.5 35.9 39.7 39.0 42.3 35.3 35.0 41.1 37.6 38.4 36.1 41.2 45.0 17.9 25.6 38.5 26.8 50.9 24.2 31.1 36.5 21.1 57.6 26.5 20.8 19.2 20.0 34.5 44.1 83.4 38.8 34.7 67.3 5.9 34.9 148.2 27.6 19.8 32.6 32.4 38.3 18.4 20.1 37.4 18.8 44.4 26.5 49.4 33.3 40.7 20.4 77.1 25.2 19.3 40.4 32.6 66.9 40.3 221.2 26.4 50.5 16.0 20.6 47.9 37.0 73.2 16.6 28.7 36.6 51.6 22.6 24.4 24.7 55.4 13.2 46.7 74.1 26.3 26.9 22.1 193.4 50.4 19.7 28.6 56.8 59.6 44.4 42.8 33.6 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GIPC1 "C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2" ENSG00000123159 "GIPC PDZ domain containing family member 1" O14908 19 14477760-14496149 "Human disease related genes, Predicted intracellular proteins" "Congenital muscular dystrophy, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 345.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 501.1;Pancreatic endocrine cells: 296.7;Paneth cells: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043958, HPA061786" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 11000 "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA043958: AB_10963436, HPA061786: AB_2756319" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (8.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-2)" "unprognostic (3.53e-2)" "unprognostic (7.72e-2)" "unprognostic (1.04e-2)" "unprognostic (7.17e-3)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" 51.0 54.8 80.0 22.4 91.5 3.3 54.3 88.7 94.4 99.8 64.7 120.2 24.7 53.7 17.6 345.8 48.9 23.4 66.1 74.5 82.1 104.1 58.4 76.3 15.9 89.4 91.4 34.4 43.5 20.8 56.0 28.7 88.1 63.6 41.1 17.9 100.9 31.0 65.1 150.2 45.5 17.5 82.0 37.7 78.7 24.9 91.1 18.6 55.8 23.3 21.0 74.1 140.1 92.3 328.1 148.6 44.7 70.6 40.6 40.7 35.2 119.7 59.8 96.7 87.3 80.3 120.6 4.7 220.3 85.2 64.6 183.8 38.7 100.6 32.6 33.8 69.0 63.9 100.7 79.7 123.7 6.9 75.3 46.7 98.5 58.8 51.3 57.4 66.0 47.2 30.1 54.4 49.9 243.8 21.3 13.3 48.6 182.1 147.8 21.7 37.4 43.7 121.6 281.6 41.8 46.2 67.1 163.2 157.0 23.1 102.5 35.1 115.4 135.7 74.6 191.7 130.1 50.5 70.5 17.3 113.9 51.9 146.2 3.0 0.7 0.1 5.1 1.1 4.7 1.9 5.1 5.1 1.1 0.8 4.2 3.3 0.3 1.5 0.5 3.6 12.0 1.7 80.0 91.5 88.7 94.4 74.5 82.1 89.4 91.4 88.1 82.0 91.1 92.3 30.6 28.9 15.2 22.9 8.3 113.9 77.4 52.1 35.9 69.8 73.6 31.6 14.8 37.1 62.8 82.8 35.5 36.3 19.3 501.1 52.8 167.9 1.1 92.2 30.5 32.4 43.1 1.7 28.8 164.3 77.1 32.6 69.3 76.8 10.2 37.3 23.2 18.0 55.9 75.7 32.2 87.8 42.7 10.8 29.8 2.4 20.5 16.1 58.7 10.3 23.4 73.3 18.6 17.1 71.6 296.7 285.4 25.2 6.8 120.4 36.0 52.7 38.0 46.0 19.7 18.1 44.5 6.4 20.4 107.0 169.8 25.7 22.9 47.7 138.1 199.7 GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Group enriched" "Detected in some" 4 "Adipocytes: 10.4;Endothelial cells: 6.2;Hepatic stellate cells: 12.8;Rod photoreceptor cells: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 19.0;HMC-1: 11.8;THP-1: 23.1;WM-115: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" 4.6 2.2 1.4 1.0 1.0 0.3 2.8 1.0 1.1 3.0 0.8 1.9 1.2 2.8 2.9 5.2 2.1 2.1 3.9 1.2 1.2 3.6 1.4 3.8 2.4 1.6 1.2 0.7 0.7 2.7 1.0 1.1 1.6 3.5 1.4 16.7 0.7 2.3 1.7 1.1 4.4 8.3 1.4 3.9 2.0 0.3 1.6 3.1 3.0 1.9 1.6 1.1 1.8 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.9 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.4 0.0 1.5 0.0 0.2 6.9 19.0 0.0 0.7 0.0 11.8 0.2 0.0 1.1 0.0 0.0 2.1 0.2 3.2 0.0 0.3 0.0 0.0 1.1 0.7 0.0 1.2 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.5 0.0 4.7 1.1 0.0 23.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 44.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.0 1.1 1.2 1.2 1.6 1.2 1.6 1.4 1.6 1.1 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.4 0.1 0.3 2.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 12.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.2 1.1 0.0 0.4 0.1 0.3 0.1 0.3 0.1 0.0 0.1 GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.3" "Cell type enhanced" "Detected in all" "Early spermatids: 97.8;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 36000 "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: AB_1078966, HPA004186: AB_1078967" "unprognostic (3.66e-1)" "unprognostic (4.46e-2)" "unprognostic (3.24e-2)" "unprognostic (6.30e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.00e-3)" "unprognostic (2.79e-1)" "unprognostic (5.23e-2)" "unprognostic (2.12e-2)" "unprognostic (3.08e-1)" "unprognostic (8.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.30e-2)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" 30.2 13.5 79.4 18.0 89.3 14.4 29.9 29.1 122.3 22.0 14.9 20.5 17.9 20.9 7.6 28.6 22.5 15.5 28.9 101.2 38.0 18.4 7.6 34.8 21.3 42.5 45.3 21.3 21.9 18.0 23.7 21.1 39.7 21.3 10.1 12.1 19.0 14.4 31.9 34.2 20.5 12.9 31.7 22.3 19.1 88.8 51.8 23.1 23.2 18.5 15.2 21.6 23.6 62.1 49.7 80.9 39.1 69.9 30.4 19.1 45.3 23.9 23.4 28.2 25.1 33.1 18.0 37.3 37.3 31.5 50.5 79.5 41.6 61.4 14.4 48.3 49.7 26.9 39.8 29.8 37.0 34.4 21.3 23.4 69.2 32.4 50.5 40.0 53.0 48.6 22.3 31.2 20.5 50.9 109.0 45.7 29.2 49.9 19.2 81.7 52.3 55.6 25.8 26.7 82.0 70.0 33.8 77.2 117.7 27.9 38.0 45.0 66.2 26.7 38.2 59.3 49.0 25.8 39.3 41.5 43.9 29.0 45.9 0.1 1.6 1.4 1.9 2.5 0.9 0.7 1.9 2.1 2.2 0.6 1.6 1.1 0.5 2.4 1.8 1.8 1.3 1.8 79.4 89.3 29.1 122.3 101.2 38.0 42.5 45.3 39.7 31.7 51.8 62.1 54.6 3.2 1.5 21.9 9.5 27.1 6.7 9.2 10.2 15.5 12.6 16.3 8.7 4.3 4.9 5.5 10.4 5.1 17.3 19.2 1.9 7.5 97.8 9.4 16.8 30.8 14.9 1.7 16.8 9.4 8.0 9.7 11.2 10.5 1.3 17.9 22.5 4.0 8.3 11.8 14.1 13.8 8.2 9.5 18.9 99.2 14.3 10.6 8.8 15.9 7.4 13.3 9.2 12.5 16.9 9.5 11.5 10.5 8.7 13.4 17.2 6.1 9.8 10.2 13.1 17.3 9.5 30.5 11.5 14.4 28.1 3.6 12.4 8.6 14.6 8.3 GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Astrocytes: 276.2;Basal keratinocytes: 234.9;Cardiomyocytes: 199.7;Endometrial stromal cells: 215.5;Granulosa cells: 494.3;Suprabasal keratinocytes: 378.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 462.7;HUVEC TERT2: 362.3;NTERA-2: 365.8;SuSa: 453.4;U-87 MG: 350.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" 121.2 287.6 313.5 24.7 310.2 0.9 60.6 260.1 409.0 261.7 193.1 17.5 18.2 98.7 10.6 74.9 32.7 99.9 168.9 273.6 362.6 21.2 10.6 67.9 21.1 340.3 380.9 43.5 19.4 236.2 31.3 290.2 307.4 83.3 19.7 3.3 35.6 148.0 10.3 388.2 24.7 112.5 335.9 4.2 30.7 36.9 373.3 24.3 169.1 22.1 34.9 116.0 184.9 341.0 0.1 43.5 186.8 0.4 99.7 61.5 0.4 142.5 286.9 46.9 113.7 0.7 0.4 0.0 15.8 55.8 40.2 18.3 5.1 87.4 151.3 0.1 51.6 2.3 15.7 0.0 124.1 0.0 0.4 164.6 92.1 172.5 61.7 462.7 362.3 0.0 0.1 4.3 9.4 8.4 0.1 80.6 365.8 0.1 47.2 0.1 0.0 3.7 188.6 21.0 0.4 2.9 0.0 0.3 0.1 453.4 14.9 0.3 269.5 143.8 39.4 122.8 93.5 0.1 0.1 0.1 350.4 0.1 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.5 310.2 260.1 409.0 273.6 362.6 340.3 380.9 307.4 335.9 373.3 341.0 152.2 250.0 80.0 276.2 0.1 234.9 133.6 71.1 77.4 0.3 9.5 20.1 199.7 0.0 17.5 1.8 2.1 53.4 0.4 0.0 0.0 76.9 0.5 21.5 215.5 166.6 0.0 0.0 0.3 4.2 7.9 124.4 0.5 51.7 8.8 494.3 33.9 0.1 8.6 0.0 0.6 0.0 4.1 0.9 55.3 1.7 2.5 3.6 44.4 15.0 0.6 0.3 0.0 4.0 1.0 10.8 0.0 4.1 0.1 29.7 0.0 0.1 6.2 0.3 0.0 5.9 80.2 0.9 1.8 68.3 378.2 20.0 4.9 127.1 0.4 52.7 GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.0" "Group enriched" "Detected in many" 4 "Sertoli cells: 157.8;Smooth muscle cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071788 Uncertain "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Cell Junctions, Cytosol" "HPA071788: " "unprognostic (1.84e-2)" "unprognostic (2.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (7.02e-2)" "unprognostic (4.01e-1)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.55e-8)" "unprognostic (5.18e-2)" "unprognostic (2.20e-1)" "unprognostic (8.52e-2)" "prognostic unfavorable (7.83e-4)" 9.5 0.7 3.1 3.6 2.8 0.8 5.2 10.1 3.8 9.2 5.5 28.6 1.6 24.7 2.9 2.7 5.3 5.4 11.8 2.3 1.4 2.2 0.7 7.2 2.7 2.1 2.9 2.2 1.4 3.4 0.6 40.0 2.6 8.9 2.9 1.0 1.1 18.6 4.6 2.0 5.3 32.7 1.3 0.7 7.6 8.8 4.0 1.6 6.7 5.9 2.0 11.4 6.1 3.0 44.5 21.9 62.0 18.9 8.3 10.6 20.5 50.3 36.6 50.0 52.6 12.4 24.7 0.5 2.3 46.4 69.9 10.1 29.2 13.7 70.8 0.5 19.8 0.4 12.1 1.6 3.8 0.3 1.7 8.8 1.6 37.0 11.8 20.4 17.1 9.6 1.8 0.5 31.4 0.4 6.7 4.3 29.5 0.1 16.2 39.5 73.8 0.3 11.4 16.8 10.2 21.5 4.6 0.5 16.2 41.3 10.9 8.0 12.3 43.8 39.3 22.2 38.9 0.4 11.3 32.5 15.9 0.3 40.7 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.2 0.2 1.0 0.5 0.1 0.2 0.1 0.1 3.1 2.8 10.1 3.8 2.3 1.4 2.1 2.9 2.6 1.3 4.0 3.0 11.7 0.0 0.0 0.7 0.2 2.0 1.7 0.5 0.0 3.4 0.6 1.4 25.1 0.0 0.2 1.8 2.1 0.5 0.4 0.1 0.0 1.5 1.5 1.4 14.9 19.5 0.0 0.0 8.1 0.0 2.6 6.3 0.0 3.0 0.0 9.4 4.2 0.3 1.5 13.5 1.4 0.0 0.0 0.3 4.2 0.3 1.5 1.2 3.6 1.0 0.6 0.2 0.0 0.0 0.3 0.6 0.0 2.2 0.0 1.4 0.0 0.3 0.2 0.9 157.8 4.8 101.1 15.6 28.4 0.6 3.0 0.5 0.8 7.8 0.1 1.3 GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Astrocytes: 301.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.1;WM-115: 34.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" 6.1 1.9 9.2 3.6 8.8 0.1 8.9 1.0 5.4 7.2 0.0 11.6 1.2 11.8 2.7 3.7 8.2 3.8 1.6 6.3 5.5 1.7 0.3 3.4 0.9 1.7 10.4 13.2 0.7 0.5 1.1 11.9 3.0 5.5 2.9 1.8 2.8 8.2 1.1 8.3 3.4 10.7 0.5 1.1 2.6 1.7 14.4 3.0 4.6 2.3 1.7 4.8 7.3 2.3 0.0 0.0 47.1 0.4 16.9 23.6 3.5 3.1 9.0 9.3 12.8 0.0 0.0 0.0 1.7 22.1 22.7 10.1 8.7 8.9 10.8 0.0 7.0 0.0 6.0 0.0 9.0 0.0 0.1 21.0 12.9 10.6 6.8 5.7 10.6 5.4 0.0 0.2 5.6 5.6 0.4 0.0 20.9 0.0 21.2 12.4 0.1 1.4 0.2 6.4 1.5 0.0 6.3 7.0 4.1 23.8 8.0 0.1 11.3 13.6 18.8 16.0 6.0 0.1 0.0 0.0 7.3 0.2 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 8.8 1.0 5.4 6.3 5.5 1.7 10.4 3.0 0.5 14.4 2.3 2.9 0.0 7.7 301.3 0.2 23.5 7.2 8.5 31.9 1.6 20.5 27.1 1.8 0.0 2.3 1.8 0.0 21.1 0.5 0.0 0.0 0.0 16.6 2.4 12.6 3.4 0.0 0.0 0.8 0.0 13.6 25.9 0.0 4.6 1.3 10.5 3.9 0.0 3.3 0.0 3.6 0.1 6.1 0.3 6.3 5.4 19.3 0.4 8.8 22.5 0.0 13.6 0.0 8.5 0.7 0.1 0.0 3.4 1.2 6.6 0.0 3.8 1.5 1.1 13.1 17.0 12.1 0.3 2.2 7.9 15.5 34.2 0.7 5.2 0.1 5.0 GLIS1 FLJ36155 ENSG00000174332 "GLIS family zinc finger 1" Q8NBF1 1 53506237-53738106 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.1;seminal vesicle: 7.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.6;Excitatory neurons: 28.0;Inhibitory neurons: 13.3;Proximal tubular cells: 4.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.0" "Region enhanced" "Detected in some" "cerebral cortex: 2.2;hippocampal formation: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.5;GAMG: 5.9;hTERT-RPE1: 4.7;PC-3: 7.3;U-138 MG: 5.1" "Not detected" "Not detected" HPA001409 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Mitochondria, Cytosol" "HPA001409: AB_1078974" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-2)" "unprognostic (8.91e-3)" "unprognostic (1.92e-1)" "unprognostic (2.27e-3)" "unprognostic (2.30e-1)" "unprognostic (3.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.93e-1)" "unprognostic (4.06e-2)" "unprognostic (1.55e-1)" "unprognostic (6.37e-4)" "unprognostic (1.98e-4)" 1.0 0.1 0.5 0.4 0.5 0.0 1.2 0.2 2.2 5.1 0.0 0.3 0.3 0.9 0.5 0.8 0.8 0.6 1.0 2.2 0.0 4.3 0.0 0.2 0.1 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 8.1 0.0 0.0 0.8 7.6 0.1 2.0 0.6 0.2 0.1 0.2 0.8 2.3 0.0 0.2 0.4 0.0 0.0 2.6 4.6 0.3 0.0 0.0 0.0 0.4 2.8 3.7 0.0 2.0 4.5 1.7 1.3 0.0 0.0 0.0 0.1 2.1 5.9 0.0 0.0 0.0 0.5 0.0 1.3 0.0 1.4 0.1 1.0 0.0 0.0 2.5 0.2 2.1 2.0 4.7 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.9 0.1 1.3 0.0 0.0 3.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 2.2 2.2 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 1.3 0.1 6.6 0.0 0.0 4.0 1.3 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.2 0.1 0.0 0.0 28.0 0.0 0.0 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 1.0 2.9 0.3 0.0 3.6 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 1.2 0.1 0.1 0.0 4.8 0.0 0.0 0.0 0.4 0.8 1.8 2.8 0.3 1.7 0.1 0.1 0.1 0.0 0.1 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 2571.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 55.4 62.3 69.4 38.9 74.1 31.6 74.2 74.6 83.4 55.9 77.2 51.8 116.3 57.8 110.9 60.0 72.3 41.4 88.9 72.6 76.2 87.2 157.7 66.6 48.4 73.7 72.8 82.8 42.1 106.1 23.2 64.1 75.1 171.4 52.3 100.3 43.2 62.1 154.2 66.6 67.7 61.8 77.9 48.2 48.5 27.9 72.9 50.0 54.8 128.8 60.3 52.4 51.6 77.1 201.6 92.0 257.4 256.7 119.2 213.9 227.0 171.1 161.4 235.4 243.0 224.4 75.3 222.5 132.2 137.5 280.1 129.5 222.5 221.1 295.8 203.8 343.0 329.4 105.7 211.3 178.5 126.7 2571.5 183.9 133.5 223.7 159.0 153.2 258.5 154.9 264.7 143.6 223.3 170.6 199.5 160.5 185.5 179.2 176.7 171.0 311.1 145.8 217.8 149.9 199.3 201.3 120.6 165.4 329.8 175.9 192.4 628.3 107.6 182.0 167.1 159.8 275.9 112.7 227.0 608.6 66.1 322.7 299.6 23.7 20.7 15.3 35.5 33.4 48.0 51.9 35.3 36.7 39.0 51.4 32.7 34.9 2.7 23.5 26.9 60.4 34.1 33.3 69.4 74.1 74.6 83.4 72.6 76.2 73.7 72.8 75.1 77.9 72.9 77.1 69.2 131.4 174.4 26.1 86.3 64.6 112.6 88.2 37.0 56.1 67.7 55.8 133.2 58.6 84.5 90.1 20.9 102.7 68.3 34.1 248.4 132.1 4.5 76.2 58.8 74.3 36.5 83.5 23.9 73.3 323.0 86.0 53.0 67.5 71.4 78.7 161.0 114.0 78.8 69.0 21.9 39.3 99.7 125.7 72.8 6.5 83.9 70.0 104.9 17.8 92.6 190.3 49.4 25.1 24.8 77.3 36.0 109.9 86.4 178.8 103.2 132.2 80.7 65.5 46.0 62.0 70.9 15.0 16.1 77.2 88.2 73.2 62.4 123.7 63.4 130.2 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52295257 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 275.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 183.0;Proximal enterocytes: 105.2;Proximal tubular cells: 83.0" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" 14.8 8.3 1.0 4.5 0.9 6.7 9.3 0.5 1.5 2.9 0.9 11.4 22.4 3.2 0.6 3.8 2.7 2.2 4.4 0.9 1.2 24.9 275.1 4.2 4.6 1.4 0.9 2.4 5.9 2.5 2.9 2.2 1.2 3.7 3.6 0.6 3.1 1.0 3.6 1.9 21.7 1.6 0.4 8.9 8.5 2.3 1.2 2.3 4.1 1.0 3.2 3.3 2.5 1.2 2.9 5.8 3.4 1.2 15.7 2.4 1.8 2.4 2.6 4.6 3.9 12.1 2.4 6.7 1.6 2.7 3.7 1.6 1.7 7.8 0.8 2.0 1.8 9.3 7.5 16.2 1.7 2.8 5.0 2.4 3.5 7.6 3.2 2.1 10.2 5.2 2.4 4.5 3.6 1.9 5.9 2.7 1.5 14.2 4.2 1.9 2.5 11.1 5.8 3.9 1.9 1.9 2.6 1.4 3.0 1.0 3.2 1.7 3.8 3.5 4.1 2.4 6.1 5.1 3.9 5.4 2.7 4.9 2.2 2.2 5.2 6.6 5.6 2.8 2.6 4.4 4.2 4.9 5.6 2.6 3.3 4.3 4.4 3.6 3.5 3.4 6.6 3.7 1.0 0.9 0.5 1.5 0.9 1.2 1.4 0.9 1.2 0.4 1.2 1.2 5.4 6.4 3.2 0.7 8.2 0.4 3.2 4.1 1.8 1.6 2.1 1.4 1.6 18.6 3.0 9.2 0.0 7.9 9.2 18.4 19.6 5.4 0.3 4.4 2.7 8.3 23.4 26.5 0.6 6.2 5.3 2.9 27.0 8.6 1.3 3.4 14.6 183.0 13.2 0.0 0.4 15.8 2.0 16.6 2.4 0.0 1.2 9.1 3.6 1.0 7.7 1.2 9.2 0.5 0.7 4.0 40.6 0.0 13.5 2.8 105.2 83.0 2.4 1.5 0.0 2.7 2.7 1.8 8.3 2.1 1.3 11.1 9.3 7.7 24.9 4.3 GMFB GMF ENSG00000197045 "Glia maturation factor beta" P60983 14 54474484-54489026 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Approved Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (7.93e-2)" "unprognostic (7.69e-3)" "unprognostic (4.81e-3)" "unprognostic (2.99e-2)" "unprognostic (1.12e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.48e-2)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "prognostic favorable (9.48e-5)" "unprognostic (1.80e-1)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (9.09e-2)" 25.2 21.8 62.8 23.5 68.8 28.8 26.0 61.6 90.4 18.6 39.8 35.0 33.5 19.3 14.0 15.8 14.2 16.5 17.2 61.4 75.6 33.6 25.8 24.2 25.3 73.0 64.5 16.1 12.8 20.1 12.3 26.5 71.4 14.8 35.2 18.4 10.7 12.9 7.0 13.7 29.5 18.2 84.0 18.4 19.0 11.1 71.9 16.2 21.9 10.2 24.4 22.3 11.4 85.3 92.7 36.9 71.8 53.2 75.8 94.5 53.9 93.2 67.9 66.2 82.1 42.6 79.4 85.2 42.4 92.0 39.5 33.4 73.7 64.0 104.4 30.9 25.4 42.5 37.4 39.9 64.7 59.9 35.5 72.0 58.8 57.1 56.0 67.9 60.8 38.4 31.4 28.8 106.1 45.7 36.8 22.9 46.4 52.1 38.9 36.9 84.7 24.4 84.4 86.3 42.4 65.5 64.6 54.4 71.4 59.0 59.8 46.4 48.1 94.9 71.9 48.7 58.4 10.4 19.4 52.0 80.0 36.3 61.5 6.8 10.2 9.1 5.0 13.3 7.0 6.6 5.9 5.1 12.6 7.8 6.2 6.6 16.1 8.0 14.0 4.4 8.5 6.2 62.8 68.8 61.6 90.4 61.4 75.6 73.0 64.5 71.4 84.0 71.9 85.3 23.3 25.6 16.2 8.1 39.3 59.9 50.2 33.6 48.9 18.4 28.0 18.0 17.3 20.0 22.6 25.8 4.2 39.3 33.7 61.8 21.5 38.7 27.3 21.5 29.5 22.2 29.9 14.5 16.8 23.3 84.5 35.1 23.9 36.1 21.6 25.4 16.8 24.5 45.4 21.9 13.6 33.6 26.4 34.6 36.4 7.5 20.2 43.0 46.2 8.4 37.8 25.7 25.7 14.1 16.5 37.3 32.1 15.8 16.9 56.0 26.0 60.5 16.4 15.4 13.1 77.0 54.5 16.0 11.4 33.5 43.8 58.3 26.2 18.8 36.2 56.2 GMFG ENSG00000130755 "Glia maturation factor gamma" O60234 19 39328353-39342372 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 577.4;lymphoid tissue: 460.7" "Cell type enhanced" "Detected in many" "Adipocytes: 304.3;Hofbauer cells: 467.5;Kupffer cells: 523.4;Langerhans cells: 343.2;Macrophages: 409.6;monocytes: 409.4;NK-cells: 423.3;T-cells: 370.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 356.7;HMC-1: 602.6;JURKAT: 464.5;Karpas-707: 494.4;NB-4: 361.6;REH: 409.8;THP-1: 641.5;U-937: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Uncertain Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (1.22e-2)" "prognostic favorable (7.35e-4)" "unprognostic (2.37e-2)" "unprognostic (1.21e-3)" "unprognostic (9.93e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-1)" "unprognostic (4.84e-2)" "unprognostic (1.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.09e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.11e-6)" "unprognostic (3.01e-1)" "unprognostic (8.76e-3)" "unprognostic (1.06e-1)" "unprognostic (5.27e-3)" 111.6 26.3 27.1 188.6 27.4 577.4 71.3 26.9 41.6 26.0 29.3 45.6 33.8 20.7 19.6 19.7 29.0 60.8 25.1 27.9 29.1 36.8 65.9 117.7 299.5 30.7 30.1 9.2 14.4 15.6 10.8 102.4 30.5 18.5 53.2 2.0 18.9 15.0 11.4 16.2 75.0 47.8 29.1 325.3 41.5 7.4 28.6 460.7 37.6 23.6 262.7 93.5 18.3 32.6 1.4 0.0 2.0 0.4 0.0 0.0 0.7 1.1 0.3 0.3 0.2 0.3 33.1 309.6 2.4 0.3 0.1 1.5 0.0 0.7 1.2 99.7 0.5 329.7 0.4 3.5 5.1 356.7 602.6 0.7 0.6 0.5 0.8 0.8 19.2 464.5 12.3 494.4 2.4 0.0 316.6 361.6 0.6 0.1 0.2 409.8 3.2 196.8 0.5 40.9 0.8 0.5 1.3 1.9 2.1 0.6 0.8 641.5 175.7 0.2 3.2 0.8 1.1 26.9 107.3 340.0 1.7 482.4 2.7 4389.0 1574.5 3622.3 720.9 1447.6 773.8 812.5 1058.2 894.4 1139.9 742.7 1044.5 858.2 5262.9 908.0 1686.2 459.6 1840.4 2617.7 27.1 27.4 26.9 41.6 27.9 29.1 30.7 30.1 30.5 29.1 28.6 32.6 304.3 28.9 97.6 0.0 211.7 18.6 4.4 0.3 2.8 0.0 4.2 9.4 3.2 11.5 17.3 0.0 0.0 3.6 273.5 0.9 0.0 1.1 11.8 0.6 2.2 176.4 0.0 119.4 0.5 0.7 4.0 18.2 9.7 0.8 238.0 0.3 272.4 11.8 467.5 0.0 0.4 0.3 2.0 523.4 343.2 30.4 1.8 409.6 74.7 1.9 409.4 0.7 423.3 0.5 0.3 0.3 0.0 0.4 216.8 1.1 0.3 4.6 8.9 0.3 46.0 4.2 26.4 8.6 3.3 1.4 14.8 5.5 370.6 2.3 1.1 4.1 GMIP ARHGAP46 ENSG00000089639 "GEM interacting protein" Q9P107 19 19629476-19643657 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.9;lymphoid tissue: 54.3" "Cell type enhanced" "Detected in many" "B-cells: 26.6;Gastric mucus-secreting cells: 24.5;Hofbauer cells: 22.7;Kupffer cells: 33.3;Macrophages: 26.7;monocytes: 27.6;T-cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042484, HPA045481" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042484: AB_2678018, HPA045481: AB_2679343" "unprognostic (7.54e-2)" "unprognostic (5.35e-3)" "unprognostic (3.10e-3)" "unprognostic (4.54e-3)" "unprognostic (1.44e-1)" "unprognostic (1.24e-3)" "unprognostic (1.23e-2)" "unprognostic (4.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.85e-2)" "unprognostic (6.75e-3)" "prognostic unfavorable (3.97e-5)" "prognostic favorable (3.03e-4)" "unprognostic (4.92e-2)" "unprognostic (2.54e-1)" "prognostic favorable (5.15e-4)" 7.5 3.3 2.9 32.0 2.4 50.9 5.4 2.5 6.1 3.7 2.5 9.6 10.4 3.3 1.4 8.6 5.4 6.0 2.9 3.8 4.0 4.3 4.7 16.9 29.4 6.5 4.4 2.6 6.0 8.9 3.6 4.6 5.7 5.4 6.5 0.4 6.9 2.8 1.1 6.9 22.6 4.3 4.5 54.3 16.7 2.9 6.6 19.1 8.5 1.9 22.9 8.3 5.3 7.4 9.9 4.5 5.9 6.5 6.4 3.3 23.5 6.1 5.2 3.6 3.4 3.6 13.0 24.1 12.1 4.3 4.7 11.5 3.9 6.7 2.3 8.3 6.1 7.6 7.1 4.0 1.9 21.7 92.0 4.2 4.5 3.9 2.0 4.2 8.2 21.1 5.3 8.5 3.9 14.6 13.7 35.8 3.5 12.7 8.1 23.3 2.6 14.0 6.9 23.3 5.1 15.2 8.4 8.7 3.7 4.5 8.0 30.7 15.0 6.6 3.8 7.6 4.6 4.3 1.9 19.8 4.2 28.0 4.6 7.0 19.5 51.9 13.2 23.7 12.3 12.6 8.4 11.9 15.1 12.8 8.9 9.7 71.8 9.7 33.1 13.5 10.0 12.5 2.9 2.4 2.5 6.1 3.8 4.0 6.5 4.4 5.7 4.5 6.6 7.4 1.7 0.0 10.2 0.3 26.6 1.1 1.7 2.5 1.2 0.0 1.9 1.3 0.9 2.8 3.1 0.0 0.0 0.6 14.9 21.2 0.0 4.1 0.1 1.4 0.9 1.8 0.0 1.3 2.1 4.7 5.3 0.9 24.5 4.0 7.0 3.5 2.5 1.6 22.7 0.0 2.1 6.6 0.0 33.3 6.6 0.4 0.6 26.7 1.8 6.5 27.6 0.4 20.6 0.5 0.2 12.9 20.2 0.7 13.9 2.0 9.3 0.7 1.5 0.1 0.0 0.4 1.6 0.6 1.3 3.5 1.1 0.8 25.8 0.9 6.0 4.1 GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 220.0;Oligodendrocytes: 410.7;Suprabasal keratinocytes: 214.2;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 1600000 "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: AB_2677870" "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" 47.5 26.2 8.9 2.6 18.8 0.4 34.9 14.9 17.7 18.5 4.4 25.4 4.7 14.8 0.7 19.7 10.9 3.2 9.4 10.8 13.3 36.6 15.2 15.2 2.0 18.8 15.0 17.1 4.5 1.3 10.9 13.6 18.4 8.8 2.6 1.5 10.4 3.0 6.2 47.9 9.9 4.1 15.5 5.9 17.7 13.0 14.2 1.3 14.2 2.9 1.5 24.7 19.9 36.6 2.2 18.6 10.5 0.0 14.5 7.9 9.1 14.3 7.2 5.5 8.7 0.0 3.4 0.0 4.5 9.3 5.1 2.6 7.0 9.5 5.4 0.0 11.9 10.4 12.9 1.2 14.8 1.8 0.0 12.0 19.9 4.1 9.5 4.4 3.5 0.0 0.0 0.1 7.7 0.6 0.0 0.1 6.1 0.2 11.0 8.6 5.2 7.8 15.7 7.0 12.5 9.2 13.5 0.0 10.3 5.4 2.0 0.3 13.0 21.8 15.6 5.1 4.4 0.0 0.0 0.2 6.1 1.2 10.2 1.3 0.4 0.4 0.1 0.4 0.0 0.0 0.1 0.1 1.9 0.1 1.1 0.5 0.3 12.8 1.0 0.2 0.1 0.4 8.9 18.8 14.9 17.7 10.8 13.3 18.8 15.0 18.4 15.5 14.2 36.6 121.1 19.2 13.8 11.4 0.9 220.0 20.6 81.6 35.3 3.9 7.0 7.7 6.7 21.5 42.3 29.5 0.0 83.6 1.3 11.1 88.0 7.2 1.7 23.2 58.5 31.5 19.9 4.2 71.4 3.8 84.6 35.9 4.6 40.3 30.3 43.9 17.5 20.0 10.0 26.9 77.4 7.8 36.7 1.0 28.6 7.0 33.5 3.9 103.2 4.7 2.9 49.1 0.0 53.3 410.7 9.4 6.3 74.4 1.2 17.4 0.9 18.4 36.8 5.0 111.7 10.6 70.8 9.7 45.7 31.9 214.2 183.5 2.9 2.9 10.7 19.2 GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 656.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4000000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoplasm, Plasma membrane" "HPA007704: AB_1849230" "prognostic favorable (1.03e-4)" "unprognostic (3.89e-1)" "unprognostic (3.35e-2)" "unprognostic (8.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-3)" "unprognostic (6.01e-2)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (6.24e-3)" "unprognostic (1.44e-1)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" 210.2 100.3 155.2 217.9 167.3 367.1 152.8 166.3 181.6 146.0 120.2 142.1 69.9 141.7 66.9 124.4 136.9 152.5 157.1 144.3 184.6 79.4 126.5 214.5 251.3 199.8 170.2 147.7 64.1 66.9 99.2 241.8 194.8 103.6 64.3 35.6 71.9 156.9 69.3 87.0 103.0 154.0 173.6 262.1 73.6 69.6 173.3 160.3 101.3 89.4 170.4 169.7 108.4 193.2 128.2 63.0 186.3 197.6 220.7 277.5 35.5 271.1 399.6 354.9 361.1 70.4 173.2 149.1 119.2 567.0 193.4 100.1 132.8 350.3 222.8 331.2 50.9 364.8 158.0 110.2 219.8 329.2 479.8 270.3 152.9 319.1 129.8 289.6 837.8 124.1 26.1 307.1 357.5 155.7 313.6 433.0 109.7 59.0 302.4 185.0 89.8 219.7 232.6 130.9 48.4 86.1 189.5 57.1 124.4 150.4 94.3 346.1 792.3 330.9 187.5 309.2 274.7 199.4 278.3 127.0 373.6 466.9 398.1 16.6 59.3 113.7 33.7 80.9 20.2 28.8 26.8 34.3 57.3 26.1 20.2 25.8 145.2 23.5 74.5 47.2 34.0 27.3 155.2 167.3 166.3 181.6 144.3 184.6 199.8 170.2 194.8 173.6 173.3 193.2 656.8 41.7 32.1 25.1 119.5 56.7 59.7 32.3 45.5 29.0 61.6 83.8 22.9 55.8 26.6 44.1 14.6 79.5 311.4 11.7 5.9 124.3 203.3 57.8 115.7 340.3 92.2 52.1 12.4 60.5 84.4 101.9 21.9 71.8 89.9 150.0 221.3 79.7 336.0 6.7 14.8 24.6 18.3 342.7 291.7 302.0 90.7 386.1 83.6 58.1 356.6 292.6 151.4 26.7 45.4 160.3 40.9 95.5 104.8 46.1 30.3 24.5 24.4 21.9 52.6 85.3 163.1 16.6 22.6 37.6 62.9 116.4 164.9 156.3 20.5 70.1 GNAI3 87U6 ENSG00000065135 "G protein subunit alpha i3" P08754 1 109548615-109600195 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 350.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022099, HPA042141" Approved Approved Nucleoplasm,Nucleoli,Centrosome NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Centrosome "Nucleoplasm, Nucleoli" "CAB022099: , HPA042141: AB_2677870" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (9.45e-3)" "prognostic unfavorable (5.30e-6)" "unprognostic (2.56e-3)" "unprognostic (2.18e-2)" "prognostic favorable (4.59e-4)" "unprognostic (1.83e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (7.27e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-2)" "unprognostic (1.66e-2)" 12.7 8.2 5.8 14.2 6.1 27.7 11.9 7.3 7.5 10.9 8.6 11.8 10.4 12.1 8.0 21.8 8.0 11.3 4.2 6.0 6.5 11.2 15.3 9.7 14.1 6.7 5.9 8.8 9.3 8.9 1.8 14.8 6.8 10.3 11.8 17.8 7.7 9.0 3.8 18.4 10.6 13.6 6.3 11.4 9.0 8.7 6.2 14.2 8.0 5.5 15.9 15.5 4.0 7.3 48.3 16.4 31.0 17.3 28.4 35.0 25.7 35.3 28.6 36.0 35.5 24.4 16.1 25.3 22.4 37.6 21.6 24.5 30.0 35.3 49.4 29.2 18.0 22.1 26.3 21.9 25.1 34.9 18.8 25.2 30.4 41.3 27.8 24.2 42.8 19.1 29.8 24.2 35.5 32.9 27.3 28.4 31.3 23.0 19.1 19.2 73.6 16.6 37.4 35.4 19.5 34.9 24.7 27.6 39.4 22.8 21.1 30.5 36.7 29.4 40.7 44.9 39.2 25.6 30.2 29.2 47.6 34.4 47.1 32.4 29.7 57.8 21.1 44.3 22.4 20.1 20.4 20.6 31.9 17.1 16.8 19.4 53.8 19.9 44.6 14.2 23.8 36.3 5.8 6.1 7.3 7.5 6.0 6.5 6.7 5.9 6.8 6.3 6.2 7.3 104.0 44.8 31.5 17.0 76.6 151.2 104.3 92.2 63.2 29.9 67.7 45.3 14.3 37.1 61.0 58.8 350.3 80.3 98.8 63.9 64.6 97.9 14.7 65.5 71.5 82.6 84.3 43.8 37.5 101.7 153.7 69.2 55.5 110.9 46.3 50.1 56.7 57.2 107.9 25.2 36.4 72.3 59.0 115.0 106.9 9.4 48.7 127.4 74.7 31.9 102.4 47.9 45.3 35.7 31.3 101.6 58.9 47.4 66.3 72.5 48.9 53.5 51.7 26.2 52.6 59.0 77.6 68.6 54.7 82.1 188.4 106.9 94.3 51.7 63.5 143.0 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNB5 GB5 ENSG00000069966 "G protein subunit beta 5" O14775 15 52115100-52191392 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 120.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 267.5;Cone photoreceptor cells: 279.4;Muller glia cells: 206.9;Rod photoreceptor cells: 296.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032353, HPA041942, HPA044198" Uncertain Approved "Nuclear speckles,Centrosome,Rods & Rings" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear speckles" "Centrosome, Rods & Rings" "CAB032353: AB_2263274, HPA041942: AB_10794309, HPA044198: AB_2678853" "unprognostic (2.38e-2)" "unprognostic (3.58e-1)" "unprognostic (1.97e-3)" "prognostic favorable (1.47e-6)" "unprognostic (6.15e-2)" "unprognostic (1.37e-2)" "unprognostic (2.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.67e-3)" "unprognostic (2.10e-1)" "prognostic favorable (3.32e-11)" "unprognostic (1.40e-3)" "unprognostic (8.12e-3)" "unprognostic (3.55e-3)" "unprognostic (1.52e-1)" 11.2 14.5 20.7 11.8 22.5 5.4 12.7 26.7 28.3 27.1 8.7 18.8 5.9 28.3 17.2 11.8 26.8 20.8 22.8 21.9 25.6 36.3 18.8 8.9 21.9 22.5 13.6 49.4 18.9 40.6 25.9 5.7 23.4 16.6 5.5 120.0 11.2 25.5 2.5 8.7 13.1 17.4 9.4 13.5 11.1 15.7 23.6 14.9 21.7 4.7 19.9 20.8 18.1 15.1 18.9 47.6 12.9 23.1 21.5 26.9 12.5 36.1 34.8 31.4 34.0 13.3 13.9 32.6 11.0 29.7 52.9 27.0 23.1 34.3 23.6 25.5 17.5 21.8 60.7 15.6 25.7 11.0 75.8 25.0 28.3 25.2 9.3 33.3 19.9 28.2 1.7 29.9 34.8 33.6 17.6 31.4 12.1 6.3 20.9 23.4 44.9 40.0 22.4 56.7 20.8 18.0 34.6 3.2 28.7 15.8 11.1 33.9 49.5 28.1 30.7 32.2 36.8 18.9 39.0 35.7 58.9 26.6 46.2 10.1 3.8 0.4 21.4 3.8 17.6 41.5 27.2 25.5 10.1 43.8 25.2 21.9 2.2 23.6 3.2 20.6 42.5 18.7 20.7 22.5 26.7 28.3 21.9 25.6 22.5 13.6 23.4 9.4 23.6 15.1 15.9 22.4 23.8 17.0 79.5 19.2 22.8 15.5 21.1 267.5 20.7 27.9 18.3 34.3 21.8 18.4 279.4 4.8 27.1 2.7 19.6 28.9 1.8 28.3 28.7 17.7 19.7 6.1 72.8 18.5 24.8 23.5 8.6 59.9 29.8 20.1 13.6 10.0 3.8 111.0 67.7 1.7 14.2 6.2 15.2 4.6 39.7 20.5 19.6 8.4 4.0 206.9 15.5 22.1 7.8 19.1 5.1 116.9 18.7 10.9 0.8 36.3 24.6 296.5 46.0 16.6 23.9 2.1 6.2 10.8 16.3 2.9 31.9 20.1 2.8 17.8 GNL3 "C77032, E2IG3, MGC800, NS" ENSG00000163938 "G protein nucleolar 3" Q9BVP2 3 52681156-52694497 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020770, HPA036742, HPA036743" Enhanced Enhanced "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No 13000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim" "Nuclear bodies, Mitotic chromosome" "CAB020770: , HPA036742: AB_2675282, HPA036743: AB_2675283" "unprognostic (4.40e-1)" "unprognostic (9.30e-2)" "unprognostic (4.10e-3)" "unprognostic (2.21e-1)" "unprognostic (5.11e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.46e-1)" "unprognostic (3.29e-3)" "unprognostic (1.14e-2)" "unprognostic (1.67e-3)" "prognostic unfavorable (6.11e-4)" "prognostic unfavorable (5.69e-5)" "unprognostic (1.33e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-3)" "unprognostic (1.06e-2)" 47.2 47.1 17.1 42.1 17.0 27.4 68.8 18.4 24.4 38.8 18.7 40.0 38.8 33.8 25.6 65.0 28.2 28.0 29.6 17.9 19.4 33.4 50.3 29.7 51.5 17.9 17.7 35.8 60.7 27.1 35.9 36.4 17.8 46.7 46.0 16.0 46.4 26.3 78.2 39.1 29.6 32.2 16.9 34.0 41.0 26.8 17.9 35.9 28.6 42.9 64.9 92.3 41.3 19.1 110.4 79.1 114.4 125.3 105.6 105.1 178.1 133.0 101.5 135.4 100.6 121.3 80.8 255.4 42.2 100.1 104.6 78.2 189.1 125.1 180.5 156.3 134.6 196.8 139.0 189.3 218.1 283.7 138.0 96.1 216.5 147.8 224.1 90.3 107.8 99.7 214.8 136.2 93.8 77.7 170.6 162.1 195.6 153.4 151.2 99.3 93.0 315.0 108.9 153.9 81.4 105.6 82.1 190.5 193.6 101.7 74.7 155.8 86.6 92.8 100.0 139.2 281.7 147.6 252.0 387.0 96.9 203.5 148.4 1.2 15.2 3.3 19.9 16.7 34.1 28.7 26.8 24.1 26.1 23.9 30.4 29.4 1.8 26.1 12.9 40.7 18.8 20.2 17.1 17.0 18.4 24.4 17.9 19.4 17.9 17.7 17.8 16.9 17.9 19.1 34.6 22.4 48.2 5.2 84.3 163.7 146.0 111.9 77.4 19.0 72.6 46.4 51.3 25.8 144.9 12.9 10.4 73.2 78.5 42.8 41.1 105.1 54.4 44.7 76.5 53.4 47.8 51.5 11.6 104.6 117.5 92.9 47.9 53.0 63.1 47.5 23.2 41.9 40.9 21.9 11.1 71.7 67.1 24.2 77.6 28.2 51.9 43.0 78.2 5.6 59.5 17.7 38.1 7.1 9.4 99.9 34.4 34.3 122.3 126.1 19.1 47.2 56.5 14.8 6.6 106.2 79.1 37.9 74.4 59.4 153.7 90.3 63.0 74.5 85.8 135.7 GNL3L "FLJ10613, GNL3B" ENSG00000130119 "G protein nucleolar 3 like" Q9NVN8 X 54530183-54621521 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036314, HPA036315" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoli "Nucleoplasm, Cytosol" "HPA036314: AB_10669986, HPA036315: AB_2675055" "unprognostic (9.71e-3)" "unprognostic (6.58e-2)" "unprognostic (6.24e-2)" "unprognostic (1.99e-2)" "unprognostic (1.13e-2)" "unprognostic (1.38e-1)" "unprognostic (2.92e-2)" "unprognostic (5.46e-2)" "unprognostic (8.44e-2)" "unprognostic (9.97e-2)" "unprognostic (4.91e-3)" "unprognostic (7.87e-2)" "unprognostic (8.05e-3)" "unprognostic (2.99e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-3)" "unprognostic (1.10e-1)" 4.6 3.6 2.0 7.0 3.6 8.9 4.8 2.6 2.7 4.8 3.1 4.7 3.9 4.7 3.7 5.7 4.7 4.7 7.2 2.7 2.6 4.4 3.9 5.0 7.6 3.1 3.6 3.8 5.0 5.7 2.3 5.6 3.2 3.7 6.1 3.8 4.0 4.4 7.1 5.7 4.7 7.3 2.7 6.9 5.3 2.3 3.4 8.3 8.5 7.8 8.5 6.7 3.5 5.4 20.7 49.1 9.5 20.9 10.2 8.3 15.2 9.8 8.7 13.4 9.9 43.4 16.6 26.9 21.3 18.2 15.1 18.7 34.6 14.9 19.0 15.9 16.4 30.0 34.0 17.2 7.9 42.6 26.0 10.0 7.1 31.0 17.4 5.7 13.4 16.4 19.2 27.0 14.0 36.5 25.5 11.8 29.6 13.0 26.7 27.7 23.9 27.8 10.3 28.8 17.1 8.4 39.7 24.3 11.7 20.9 30.9 11.4 20.0 22.6 22.1 21.8 18.4 19.9 25.7 35.9 12.8 34.6 27.8 23.6 14.4 15.0 16.5 12.8 15.0 15.1 14.8 13.8 11.1 16.0 10.6 11.7 19.2 21.5 15.0 10.2 9.3 12.5 2.0 3.6 2.6 2.7 2.7 2.6 3.1 3.6 3.2 2.7 3.4 5.4 9.2 12.8 18.5 14.4 15.3 1.3 3.6 3.9 9.6 10.2 6.1 3.9 8.5 8.6 11.8 3.7 12.5 7.1 14.1 7.4 3.9 9.4 0.4 8.2 17.2 9.4 3.5 12.0 14.8 8.7 6.4 7.4 10.7 9.6 10.8 10.9 7.1 4.6 4.9 8.4 14.8 4.7 8.2 9.4 4.2 0.0 5.6 9.4 0.0 14.0 12.0 3.4 25.7 16.1 23.2 9.8 3.9 3.0 10.0 4.2 6.8 5.3 7.8 9.3 6.6 8.5 7.1 1.1 7.7 6.6 2.0 5.5 11.9 9.5 7.6 3.6 GOLGA6A "GLP, GOLGA6" ENSG00000159289 "Golgin A6 family member A" Q9NYA3 15 74069857-74082550 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "liver: 4.1;testis: 15.1" "Cell type enriched" "Detected in some" 8 "Early spermatids: 47.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (1.68e-1)" "unprognostic (2.09e-2)" "unprognostic (9.50e-2)" "unprognostic (9.67e-2)" "unprognostic (6.70e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 15.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GOLGA6B ENSG00000215186 "Golgin A6 family member B" A6NDN3 15 72654738-72666394 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 19 "liver: 3.5;testis: 7.2" "Group enriched" "Detected in some" 4 "Astrocytes: 3.9;Early spermatids: 8.6;Excitatory neurons: 2.7;Inhibitory neurons: 2.7;Oligodendrocytes: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (5.47e-3)" "unprognostic (1.88e-2)" "unprognostic (2.07e-1)" "unprognostic (2.01e-1)" "unprognostic (2.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GOLGA6C ENSG00000167195 "Golgin A6 family member C" A6NDK9 15 75258599-75270199 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 9.9" "Cell type enriched" "Detected in some" 6 "Early spermatids: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (6.53e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GOLGA6D ENSG00000140478 "Golgin A6 family member D" P0CG33 15 75282835-75295807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 12.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (7.95e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 12.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 GORAB "FLJ11752, GO, NTKL-BP1, SCYL1BP1" ENSG00000120370 "Golgin, RAB6 interacting" Q5T7V8 1 170532131-170553834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027250, HPA027746" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA027250: AB_10611253, HPA027746: " "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-3)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (5.26e-4)" "unprognostic (8.48e-3)" "unprognostic (2.94e-2)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (7.83e-12)" "unprognostic (2.52e-2)" "unprognostic (2.83e-1)" "unprognostic (7.71e-2)" "unprognostic (1.70e-1)" 3.1 5.2 1.6 1.9 1.6 0.6 2.8 1.6 3.1 3.8 1.9 3.6 1.4 3.2 3.5 2.3 2.1 2.1 3.1 1.5 2.3 2.5 4.3 2.5 3.6 1.6 1.8 4.3 3.7 1.9 3.0 3.1 1.7 2.8 3.3 1.3 3.3 2.6 1.1 1.9 2.7 2.0 1.7 3.1 2.1 2.0 2.0 2.8 3.0 2.1 3.0 3.1 3.3 1.8 3.4 3.8 4.5 2.0 9.0 5.8 2.9 4.8 7.5 3.6 4.6 1.9 4.9 5.1 6.1 4.3 2.4 4.0 6.4 2.8 6.0 4.8 1.6 2.5 4.0 2.8 4.9 4.4 3.1 4.4 2.5 4.2 3.9 5.5 3.5 2.3 4.4 2.3 5.3 0.6 5.8 4.0 4.7 6.2 4.0 3.9 3.8 6.0 4.2 1.9 1.4 3.0 3.6 4.8 11.5 3.1 2.7 8.4 4.4 6.8 3.1 2.9 7.2 3.5 4.4 3.8 5.2 4.0 5.4 0.7 3.9 0.0 2.3 4.2 3.9 2.8 4.1 3.5 4.3 2.8 3.6 3.0 0.5 3.8 3.1 2.7 5.3 2.6 1.6 1.6 1.6 3.1 1.5 2.3 1.6 1.8 1.7 1.7 2.0 1.8 8.1 0.0 11.4 8.8 8.9 2.8 4.0 6.5 8.6 4.7 5.2 7.1 9.4 10.0 7.1 5.5 2.1 6.0 6.2 12.8 3.9 12.3 2.3 5.5 10.4 8.3 0.0 3.4 9.3 6.0 7.3 10.5 9.2 6.7 13.9 5.2 5.3 6.6 7.1 5.0 7.7 9.4 8.2 6.9 4.6 3.2 14.0 5.6 3.6 3.7 10.1 4.3 3.1 9.0 7.3 5.7 9.8 6.4 10.3 4.9 4.3 6.0 2.4 7.1 6.6 8.2 9.3 13.1 8.1 5.4 1.6 5.6 6.3 5.1 6.4 3.0 GP9 "CD42a, GPIX" ENSG00000169704 "Glycoprotein IX platelet" P14770 3 129060779-129062406 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.1;lung: 3.2;lymphoid tissue: 8.9" "Cell type enriched" "Detected in some" 8 "Macrophages: 151.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "basophil: 29.5;neutrophil: 13.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 14 "HEL: 85.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063182 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2600000 "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" Nucleoplasm "HPA063182: AB_2684956" "unprognostic (1.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.80e-2)" "unprognostic (2.50e-2)" "unprognostic (3.24e-1)" "unprognostic (2.53e-2)" "unprognostic (8.47e-2)" "unprognostic (8.70e-2)" 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.1 1.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 1.2 0.2 0.2 0.7 0.3 0.0 0.0 0.3 0.6 0.1 0.1 0.0 13.9 0.0 0.2 3.0 0.0 51.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.0 14.4 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.1 1.7 0.0 0.0 0.6 0.0 1.3 0.0 18.3 0.0 151.9 0.0 0.0 4.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.3 0.0 GPAA1 "GAA1, hGAA1" ENSG00000197858 "Glycosylphosphatidylinositol anchor attachment 1" O43292 8 144082590-144086216 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 275.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077224 Approved Approved "Endoplasmic reticulum,Centrosome,Mitochondria,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum, Cytosol" "Centrosome, Mitochondria" "HPA077224: " "unprognostic (2.53e-3)" "unprognostic (1.39e-1)" "unprognostic (3.06e-2)" "unprognostic (2.57e-2)" "unprognostic (2.49e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-3)" "unprognostic (2.64e-1)" "unprognostic (8.92e-2)" "unprognostic (1.67e-2)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (3.89e-1)" "unprognostic (1.27e-1)" "unprognostic (2.73e-2)" 47.0 75.5 35.7 21.2 37.5 48.2 46.7 39.9 43.6 52.2 62.3 46.1 35.8 56.9 18.8 51.7 45.9 25.0 72.1 35.9 35.6 61.9 69.9 42.6 23.4 41.9 37.4 49.9 66.2 47.5 37.2 20.0 40.7 50.9 13.1 11.4 60.5 40.5 71.7 47.1 46.8 18.8 40.1 48.4 55.8 40.9 38.1 18.6 60.1 28.4 12.9 43.0 42.8 47.6 67.3 117.2 26.9 84.7 60.8 51.5 92.8 68.5 66.5 55.8 57.4 49.0 108.9 36.6 94.1 73.9 26.4 82.5 17.9 67.2 8.1 60.4 59.0 58.0 53.1 36.3 58.6 28.5 83.2 56.8 61.6 56.9 39.4 45.0 46.4 61.5 42.1 125.7 54.1 237.6 55.9 26.5 27.2 79.3 275.8 38.1 34.2 176.9 48.4 46.8 45.7 63.2 88.8 112.4 51.1 14.7 73.2 79.3 31.6 51.8 88.6 29.5 77.2 70.0 57.5 24.9 91.2 34.8 72.0 35.7 64.4 59.0 84.2 78.1 57.2 37.4 41.7 66.7 59.6 40.1 40.6 57.7 14.8 69.1 91.9 107.1 40.1 76.7 35.7 37.5 39.9 43.6 35.9 35.6 41.9 37.4 40.7 40.1 38.1 47.6 41.0 38.5 40.0 13.7 46.7 28.8 54.9 84.6 37.0 60.8 74.9 59.9 42.7 55.8 58.0 44.1 64.6 123.4 72.5 100.2 25.4 125.8 5.7 30.8 30.7 37.3 56.9 48.0 12.8 89.9 152.9 57.1 56.6 37.3 64.8 45.1 42.5 74.9 86.6 55.5 14.6 52.6 79.3 53.6 25.6 10.9 40.4 41.2 72.9 6.5 57.4 98.0 98.9 15.6 20.4 76.0 91.0 37.6 85.5 58.0 155.1 90.3 46.8 73.2 59.2 50.8 50.5 194.8 109.9 55.9 22.3 109.3 38.9 66.5 85.3 48.1 GPATCH1 "ECGP, FLJ10206, FLJ38686, GPATC1" ENSG00000076650 "G-patch domain containing 1" Q9BRR8 19 33080899-33130542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043430, HPA043604, HPA074327" Approved Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cell Junctions" "HPA043430: AB_10960493, HPA043604: AB_10960499, HPA074327: " "unprognostic (2.38e-2)" "unprognostic (1.71e-2)" "unprognostic (9.95e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.41e-1)" "unprognostic (1.28e-2)" "unprognostic (4.60e-3)" "unprognostic (3.54e-2)" "unprognostic (5.17e-2)" "unprognostic (3.56e-2)" "unprognostic (6.53e-2)" "unprognostic (5.37e-3)" "unprognostic (8.10e-2)" "unprognostic (4.57e-2)" "unprognostic (1.25e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-3)" 3.5 3.1 3.0 3.5 3.2 3.7 4.4 5.1 4.0 4.0 2.0 4.8 5.4 4.5 4.4 4.3 3.9 2.8 3.8 3.1 2.9 4.4 3.4 3.4 4.9 2.8 3.0 7.2 3.8 6.3 2.6 4.2 3.0 4.2 4.5 3.9 4.6 3.4 4.2 5.6 4.6 4.4 2.7 4.3 4.9 4.4 3.3 5.9 4.7 3.2 5.0 3.6 3.6 3.4 8.8 18.2 8.4 9.1 5.5 6.2 7.1 7.8 5.4 11.6 9.7 12.9 7.9 12.3 9.7 6.2 5.5 7.7 10.6 6.4 10.1 21.4 6.6 11.7 6.8 9.8 7.2 20.3 7.6 5.3 7.4 7.9 7.2 5.6 6.6 9.6 12.5 7.7 5.8 11.2 11.8 7.1 5.9 11.5 7.5 11.9 10.6 5.5 5.4 5.4 9.3 6.2 12.3 7.6 4.6 7.2 6.4 14.5 7.5 10.2 7.6 5.6 11.3 6.4 11.1 10.6 6.3 10.3 9.5 23.1 6.4 7.4 6.0 6.6 4.1 6.2 5.6 7.7 6.0 7.0 9.6 6.0 4.7 3.5 3.7 5.3 9.2 5.0 3.0 3.2 5.1 4.0 3.1 2.9 2.8 3.0 3.0 2.7 3.3 3.4 6.5 9.6 7.9 5.9 9.1 6.1 5.0 6.0 10.8 9.7 5.2 4.6 11.8 1.5 9.8 7.3 14.6 10.5 10.7 12.0 15.6 6.8 3.2 5.2 9.4 6.4 4.2 4.2 7.2 4.5 5.2 7.5 10.2 6.8 16.5 10.1 7.9 4.6 4.1 3.3 7.0 7.7 8.2 6.0 5.2 2.1 10.2 5.8 8.8 2.8 5.8 7.1 16.5 5.5 7.0 9.0 8.7 8.2 5.5 3.3 6.8 6.6 10.3 11.9 0.0 8.0 7.3 19.5 14.8 6.5 3.7 5.5 9.1 7.0 6.5 3.4 GPBP1 DKFZp761C169 ENSG00000062194 "GC-rich promoter binding protein 1" Q86WP2 5 57173948-57264679 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 622.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037773 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" "Plasma membrane" "HPA037773: AB_10671721" "unprognostic (1.53e-1)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.49e-1)" "unprognostic (8.30e-2)" "unprognostic (9.68e-3)" "unprognostic (1.24e-2)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (3.70e-1)" "unprognostic (5.93e-2)" "unprognostic (5.48e-2)" "unprognostic (3.75e-2)" "unprognostic (1.65e-1)" "unprognostic (4.89e-2)" "unprognostic (2.57e-1)" "prognostic favorable (4.15e-5)" 39.2 48.6 67.6 37.8 72.0 66.0 55.7 87.7 87.8 46.5 63.6 38.9 31.2 42.6 48.0 36.9 47.0 36.6 39.8 66.0 67.8 48.0 44.0 43.5 57.8 66.2 68.0 65.1 35.7 50.1 41.7 43.3 66.8 42.1 36.9 83.7 42.6 36.5 59.0 38.2 40.3 32.7 68.5 48.1 37.6 75.2 67.3 69.0 51.5 56.5 53.0 43.9 38.0 85.4 56.4 45.3 83.7 70.1 53.8 51.6 75.9 42.9 72.4 68.6 88.4 73.0 63.2 74.2 48.0 44.0 84.9 37.5 71.9 48.6 86.8 41.7 48.1 61.9 49.6 61.5 62.9 45.2 60.8 43.6 74.8 56.1 78.1 65.8 56.7 59.5 62.3 117.6 56.4 72.3 70.3 78.6 51.2 28.2 31.3 75.4 68.5 72.7 53.7 58.7 72.7 56.0 62.1 53.4 69.6 54.3 104.9 75.8 37.3 25.0 50.2 35.1 62.0 90.0 79.6 81.6 40.7 66.7 46.9 93.8 38.2 76.4 59.6 41.0 76.3 71.5 72.1 72.6 43.7 61.9 78.5 73.8 73.2 79.5 45.5 29.8 84.9 68.8 67.6 72.0 87.7 87.8 66.0 67.8 66.2 68.0 66.8 68.5 67.3 85.4 132.9 60.9 88.3 129.3 272.2 227.5 241.1 102.6 206.1 139.8 146.1 87.9 89.0 65.8 121.9 84.6 148.0 99.0 246.9 149.6 99.7 76.5 249.9 246.6 134.0 123.1 107.7 82.7 106.4 55.9 74.3 143.2 115.2 267.8 142.8 119.0 68.2 47.0 56.2 134.6 96.4 103.3 118.0 70.3 622.0 102.4 133.9 162.8 188.5 112.4 160.7 95.7 178.2 168.9 221.6 70.5 176.3 91.4 261.6 246.5 87.9 72.6 154.6 199.0 52.6 129.7 139.9 379.3 279.6 195.6 237.7 161.7 285.2 107.0 102.0 304.1 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 45.3" "Cell type enhanced" "Detected in many" "Adipocytes: 9.6;Distal enterocytes: 15.4;Endothelial cells: 11.3;Hepatocytes: 23.5;Kupffer cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.8;myeloid DC: 5.8" "Group enriched" "Detected in many" 19 "dendritic cells: 5.8;monocytes: 2.9" "Cell line enhanced" "Detected in many" "AN3-CA: 11.5;Daudi: 12.1;fHDF/TERT166: 8.6;Hep G2: 22.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" 10.6 12.6 12.7 1.5 11.7 0.2 8.4 9.0 15.9 5.4 8.1 10.8 0.6 5.8 0.3 2.2 4.3 1.2 7.1 10.0 9.6 9.7 27.9 12.1 1.9 9.9 10.2 2.4 2.1 0.4 6.1 6.3 10.5 7.2 1.4 0.9 2.9 5.0 4.3 2.8 3.6 1.8 8.4 8.5 45.3 1.5 11.6 0.9 9.7 1.3 1.0 6.1 4.7 9.2 1.1 0.4 0.3 11.5 2.7 2.6 1.1 6.7 4.4 2.1 3.7 0.2 0.3 12.1 1.1 8.6 0.1 0.6 0.1 0.0 0.2 2.6 2.1 0.0 1.4 22.8 0.4 0.1 0.7 1.5 0.0 1.3 0.0 1.6 0.6 0.2 0.1 0.1 0.5 0.8 0.0 0.4 2.2 2.4 7.9 1.1 0.0 0.0 0.2 0.0 0.1 4.5 0.0 0.5 2.5 0.8 0.2 0.1 1.6 0.4 2.8 6.9 2.1 0.0 0.0 4.4 3.8 0.2 0.2 0.0 2.9 0.0 0.0 2.8 0.0 0.2 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.4 12.7 11.7 9.0 15.9 10.0 9.6 9.9 10.2 10.5 8.4 11.6 9.2 9.6 0.0 0.0 1.0 1.2 0.5 0.0 0.5 1.8 0.0 0.5 0.5 2.8 0.0 0.0 5.5 0.0 0.0 0.0 15.4 0.0 0.1 0.0 4.4 0.1 11.3 1.2 0.0 0.8 3.1 0.6 1.5 0.5 1.0 0.0 0.4 1.1 23.5 0.6 0.0 0.5 2.8 0.0 16.9 2.7 0.7 2.8 2.9 0.0 1.9 0.6 4.4 0.0 0.5 0.1 0.8 7.4 1.2 0.1 0.8 0.2 5.6 0.0 0.4 0.0 0.7 7.2 0.5 2.7 0.1 0.3 0.0 0.0 0.1 2.0 0.1 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPN1 "ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1" ENSG00000198522 "GPN-loop GTPase 1" Q9HCN4 2 27628247-27651511 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036793, HPA036794, CAB037303" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB037303: AB_477173, HPA036793: AB_2675318, HPA036794: AB_10672230" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (5.64e-2)" "prognostic unfavorable (2.88e-5)" "unprognostic (2.57e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.50e-2)" "unprognostic (8.27e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-3)" "unprognostic (2.34e-1)" "unprognostic (1.21e-2)" "unprognostic (2.51e-1)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" 22.8 22.8 19.3 20.3 19.8 34.1 26.4 19.9 26.1 18.1 19.5 22.7 19.9 19.1 19.9 25.5 21.0 18.6 21.3 19.4 21.6 26.3 24.6 18.6 28.7 22.5 22.6 18.4 22.8 25.9 16.6 26.5 21.8 17.7 25.6 24.9 21.5 16.9 32.4 24.8 19.6 22.4 19.6 22.2 20.6 25.5 21.9 30.1 22.8 27.2 30.3 24.0 19.5 21.2 94.6 53.3 48.8 35.4 44.3 44.8 48.7 52.0 50.5 70.7 52.1 58.0 47.4 58.8 49.2 56.4 65.4 39.5 67.6 63.4 71.5 55.4 47.6 66.8 38.3 70.7 57.3 100.0 33.7 46.7 54.8 72.6 67.1 49.4 75.2 51.5 84.7 53.5 84.1 54.2 60.3 75.1 83.4 70.9 50.7 60.2 144.4 61.0 57.9 53.5 42.9 67.6 57.2 61.5 58.4 44.7 37.1 56.0 62.9 61.5 91.1 30.9 122.7 60.8 71.8 156.9 88.0 85.0 51.8 92.4 61.3 55.1 79.1 71.6 86.0 74.6 72.2 92.0 89.7 68.7 63.8 78.2 9.3 106.1 72.1 46.8 79.2 82.3 19.3 19.8 19.9 26.1 19.4 21.6 22.5 22.6 21.8 19.6 21.9 21.2 17.6 12.8 10.4 2.3 18.7 21.7 21.7 28.2 10.8 9.2 14.8 11.8 11.8 14.3 19.7 14.7 4.2 43.5 28.8 9.5 23.5 46.4 86.3 20.5 14.1 17.3 17.4 18.7 6.6 36.3 46.2 14.3 9.7 21.7 24.7 17.7 17.5 10.2 33.4 11.8 6.6 13.0 20.3 20.1 26.8 76.0 14.9 17.6 23.2 2.8 28.9 15.0 27.8 5.0 5.0 46.3 13.5 10.9 11.2 20.1 16.2 20.8 14.3 10.9 13.1 13.2 19.0 36.6 23.4 13.6 18.6 33.1 31.0 20.2 20.0 18.9 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 203.8" "Cell type enhanced" "Detected in all" "Early spermatids: 193.1;Late spermatids: 573.0;Spermatocytes: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: AB_2684889" "unprognostic (2.25e-1)" "unprognostic (4.21e-2)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.34e-4)" "unprognostic (5.68e-2)" "unprognostic (1.83e-2)" "unprognostic (7.61e-3)" "prognostic favorable (6.18e-4)" "unprognostic (4.95e-2)" "unprognostic (8.66e-3)" "unprognostic (3.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-1)" 20.6 32.6 54.4 16.4 50.9 13.7 19.6 49.4 63.8 24.5 42.5 22.6 12.2 23.6 12.6 28.9 22.3 15.0 29.1 52.8 44.3 34.0 33.9 19.4 14.9 55.3 50.5 18.7 16.2 23.2 26.5 15.6 56.2 29.1 7.5 11.8 23.7 14.8 16.8 22.5 19.5 10.4 45.9 24.5 27.4 203.8 56.2 10.6 30.8 15.9 12.8 26.7 21.4 48.2 22.0 50.2 18.6 49.5 34.9 19.9 69.6 25.5 24.3 31.0 18.4 38.0 31.6 22.7 42.4 24.1 51.9 44.3 28.8 17.1 9.7 73.0 27.9 22.7 53.7 22.5 21.6 15.0 40.9 24.8 25.0 27.5 19.0 20.8 16.3 28.4 20.6 56.2 19.1 56.9 16.8 40.5 22.5 20.4 49.9 31.0 18.0 37.5 20.0 30.3 27.2 32.6 30.0 44.6 30.6 21.4 46.0 6.3 23.1 69.1 46.8 53.3 18.7 41.9 84.9 20.5 50.0 12.3 44.9 1.9 2.8 5.1 2.3 2.5 2.9 2.7 2.0 1.7 3.0 3.8 2.1 1.8 14.0 1.9 2.1 3.0 1.6 1.4 54.4 50.9 49.4 63.8 52.8 44.3 55.3 50.5 56.2 45.9 56.2 48.2 13.0 3.2 11.2 12.7 15.0 14.4 18.5 21.8 19.4 14.1 16.2 13.3 5.3 20.0 13.7 12.9 12.5 49.6 9.5 26.2 15.6 39.0 193.1 14.4 14.8 15.8 16.2 14.7 9.3 26.6 69.7 13.4 15.3 10.0 2.5 10.3 11.4 10.8 23.2 20.2 9.0 16.8 14.2 15.4 14.5 573.0 19.3 11.5 14.2 6.5 16.4 38.9 11.3 4.5 11.2 30.8 14.6 16.1 13.4 26.7 31.5 19.6 18.6 9.1 26.3 8.7 14.1 175.0 55.9 16.9 15.2 119.6 10.8 16.6 15.1 23.3 GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367407-74372622 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129102 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" "Langerhans cells: 268.1;monocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 31.8;SK-BR-3: 62.7;U-266/70: 30.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA028697 Uncertain Uncertain "Nucleoli,Nucleoli rim,Plasma membrane,Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Nucleoli, Nucleoli rim" "Plasma membrane, Cell Junctions" "HPA028697: AB_10601810" "unprognostic (2.83e-3)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (5.42e-2)" "unprognostic (2.13e-4)" "unprognostic (7.11e-2)" "unprognostic (7.52e-3)" "unprognostic (3.60e-2)" "unprognostic (9.20e-2)" "unprognostic (1.26e-1)" "unprognostic (9.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-3)" 3.3 4.8 0.7 4.4 0.8 1.3 3.3 1.1 1.2 7.9 10.7 3.1 4.0 2.9 1.3 30.2 2.9 2.0 12.9 1.4 0.6 2.3 9.0 6.7 3.1 1.7 0.9 4.3 4.1 15.1 1.4 8.7 1.2 3.5 2.2 0.9 8.9 2.3 59.6 22.6 2.8 1.7 0.7 3.9 3.7 2.0 1.1 2.5 3.3 23.9 7.5 6.7 13.7 1.0 9.0 5.0 1.5 4.1 1.4 1.3 8.0 2.8 1.8 2.3 3.1 4.1 3.4 1.1 3.4 3.0 2.9 18.9 4.6 1.8 3.4 25.2 7.6 0.1 16.0 6.2 4.9 0.1 2.0 1.2 3.9 3.9 2.4 2.3 1.8 3.7 1.4 31.8 0.9 6.5 3.8 1.9 1.7 4.4 6.3 0.6 1.3 4.3 1.4 6.0 2.3 6.1 10.8 62.7 5.2 3.0 8.9 1.1 13.3 7.8 2.0 20.5 1.3 30.6 5.2 0.1 5.8 12.6 3.3 0.7 0.4 0.1 0.6 0.3 0.5 0.4 0.4 0.6 0.2 0.6 0.4 0.5 1.2 0.2 0.1 0.2 0.2 0.2 0.7 0.8 1.1 1.2 1.4 0.6 1.7 0.9 1.2 0.7 1.1 1.0 3.1 6.4 8.9 0.0 5.3 13.6 10.2 17.8 12.5 0.7 14.7 8.4 13.4 2.8 12.3 5.5 2.1 34.8 2.9 6.8 0.0 3.5 0.1 13.7 6.9 4.0 0.0 0.0 1.4 3.9 10.0 4.8 5.1 26.5 0.0 3.2 2.5 14.8 4.0 1.7 1.2 4.8 10.2 0.8 268.1 0.2 1.8 13.1 7.2 0.0 107.4 1.0 0.0 0.0 0.2 13.9 4.3 5.3 4.7 6.8 7.5 1.6 7.4 1.4 0.0 5.5 4.2 0.6 2.3 43.6 24.3 48.2 3.5 5.0 5.5 16.1 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "B-cells: 6.6;dendritic cells: 30.6;Plasma cells: 4.2;T-cells: 18.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "JURKAT: 42.3;MOLT-4: 75.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 0.8 0.4 0.5 6.9 0.3 2.5 0.9 0.6 0.6 0.4 0.3 1.0 2.0 0.5 0.6 0.3 0.3 1.1 0.3 0.4 0.4 0.5 1.0 1.9 15.2 0.7 0.5 0.2 0.1 0.1 0.1 0.2 0.7 0.7 1.6 0.2 1.5 0.1 0.2 0.2 3.6 0.3 0.3 8.1 2.1 0.1 0.4 16.9 0.9 0.1 10.4 1.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.2 0.0 0.0 75.1 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.2 0.0 0.0 0.0 6.5 0.0 3.6 3.6 2.0 1.2 2.5 4.8 6.1 0.1 2.6 4.2 4.9 0.3 4.6 5.5 1.0 4.8 1.6 0.5 0.3 0.6 0.6 0.4 0.4 0.7 0.5 0.7 0.3 0.4 0.5 0.7 0.0 2.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.6 1.8 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 10.3;Breast myoepithelial cells: 7.5;Collecting duct cells: 12.9;Glandular and luminal cells: 8.1;monocytes: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.2" "Cell line enhanced" "Detected in some" "EFO-21: 17.9;HL-60: 17.5;MCF7: 14.6;NTERA-2: 28.9;RPTEC TERT1: 13.6;SH-SY5Y: 10.9;T-47d: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" 1.4 4.0 21.3 1.5 22.9 15.7 3.9 13.0 19.7 3.5 7.4 1.6 0.3 5.0 2.8 3.7 6.8 1.0 3.4 19.9 20.6 3.2 0.1 1.4 0.2 18.0 18.3 4.4 3.1 17.3 9.2 1.2 16.2 5.1 0.5 1.8 1.4 4.3 0.7 2.1 0.7 2.9 19.7 3.3 2.0 4.7 22.9 0.5 6.2 1.9 0.2 2.0 2.3 18.9 0.0 1.1 1.9 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 17.9 0.0 0.8 0.1 4.3 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 17.5 0.9 0.0 2.9 0.0 1.2 0.0 0.0 3.7 0.0 0.0 0.0 14.6 1.2 0.2 28.9 0.0 0.0 0.0 0.0 0.0 13.6 7.8 3.0 10.9 3.8 0.0 0.0 3.6 9.9 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 2.8 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 7.2 0.0 0.1 0.0 0.0 0.1 21.3 22.9 13.0 19.7 19.9 20.6 18.0 18.3 16.2 19.7 22.9 18.9 0.2 0.0 1.1 0.0 0.1 1.9 4.2 0.0 4.0 10.3 6.5 7.5 3.5 2.8 1.3 12.9 4.2 1.4 0.4 0.2 1.9 0.7 0.2 2.1 4.9 0.4 1.2 1.7 0.0 0.0 1.3 1.2 1.1 8.1 0.0 2.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 4.4 0.3 0.0 0.9 3.2 0.0 0.0 8.6 0.5 1.0 0.0 0.0 0.3 0.1 1.2 0.0 5.6 0.0 0.1 1.5 0.4 0.0 2.3 1.7 0.2 4.8 4.7 1.7 0.3 0.7 0.5 0.3 2.0 GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122917-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 76.4" "Cell type enhanced" "Detected in some" "Astrocytes: 91.7;Muller glia cells: 59.6;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 20.4" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.2;MCF7: 1.5;T-47d: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" 0.1 0.2 55.2 0.0 71.1 0.2 0.0 60.7 52.2 0.2 10.6 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 48.0 50.7 0.0 0.2 0.0 0.0 66.7 67.0 0.0 0.0 0.0 0.6 0.0 53.7 0.2 0.2 2.8 0.1 0.3 0.1 0.1 0.3 0.1 59.4 0.0 0.2 0.3 76.4 0.0 0.1 0.1 0.0 0.0 0.1 53.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 55.2 71.1 60.7 52.2 48.0 50.7 66.7 67.0 53.7 59.4 76.4 53.1 0.0 0.0 0.0 91.7 0.1 0.4 0.5 0.7 0.0 1.2 0.3 0.3 1.1 1.5 1.7 0.0 4.2 0.1 0.0 4.9 0.0 3.2 4.5 0.9 0.2 0.1 0.0 0.0 0.4 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.8 0.9 0.1 0.0 2.8 0.0 59.6 0.0 89.0 20.4 2.1 2.7 1.9 0.0 0.8 1.3 0.1 1.1 4.9 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.7 0.1 0.2 0.7 1.0 GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794125-96837477 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 31.4;Excitatory neurons: 46.2;Granulosa cells: 31.2;Inhibitory neurons: 20.3;Late spermatids: 35.2;Spermatocytes: 24.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 8.8;HHSteC: 13.5;Karpas-707: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: AB_10672841" "unprognostic (8.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-3)" "unprognostic (3.00e-1)" "unprognostic (2.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" 0.5 0.9 1.4 0.7 3.5 0.1 0.4 0.7 2.7 1.5 2.7 1.2 1.5 0.5 0.3 0.5 0.7 0.7 0.5 1.5 0.1 0.3 0.0 0.3 0.1 1.6 0.6 1.0 1.4 1.0 0.9 0.7 2.0 0.9 1.8 0.2 0.4 0.5 0.2 0.4 1.1 0.6 0.0 0.3 1.1 2.4 0.9 0.6 0.6 0.1 0.2 0.8 1.4 1.8 0.0 0.1 1.6 0.4 2.3 0.8 0.4 1.0 0.0 0.0 0.2 0.2 1.2 0.1 0.0 0.1 1.3 1.2 5.4 2.5 0.0 8.8 4.1 5.2 0.4 0.0 13.5 3.3 0.6 2.5 0.4 0.0 3.7 0.3 0.0 7.6 3.8 20.8 0.5 0.4 2.5 0.0 5.4 0.0 0.7 0.0 1.9 4.3 0.3 0.2 2.4 1.5 0.3 3.3 0.6 1.7 1.3 0.7 0.0 1.4 2.1 0.2 2.0 1.6 0.9 0.1 0.8 2.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 1.4 3.5 0.7 2.7 1.5 0.1 1.6 0.6 2.0 0.0 0.9 1.8 0.6 0.0 0.0 2.3 0.2 1.9 0.7 0.3 4.0 1.5 0.6 0.9 0.7 2.8 0.1 1.8 0.0 0.2 0.3 0.1 0.0 0.4 31.4 0.1 0.5 0.7 3.0 0.4 46.2 0.9 0.7 2.5 1.1 0.1 0.0 31.2 1.1 0.0 0.2 0.0 20.3 0.5 0.0 0.0 8.9 35.2 3.4 0.4 1.8 9.4 0.1 0.2 0.0 11.6 4.8 0.4 0.1 4.9 1.0 1.1 0.1 0.2 0.0 0.2 0.0 0.4 2.2 24.6 10.5 1.9 0.3 0.1 0.4 2.1 0.5 0.3 GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.6;lymphoid tissue: 9.6" "Cell type enhanced" "Detected in many" "dendritic cells: 256.1;granulocytes: 317.8;Kupffer cells: 112.5;monocytes: 90.9;NK-cells: 319.3;T-cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 5.7;HEL: 6.2;HL-60: 7.5;HMC-1: 9.0;RH-30: 11.5" "Not detected" "Not detected" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" 2.0 1.1 0.5 9.1 0.6 12.6 0.9 0.5 0.8 1.1 0.6 1.2 1.6 0.7 0.4 0.9 0.7 2.8 0.6 0.4 1.0 0.8 2.7 4.3 8.8 1.9 1.0 0.3 0.4 0.4 0.4 1.7 1.6 0.8 1.5 0.1 0.7 0.5 0.2 0.3 2.4 2.3 1.0 9.6 1.6 0.6 1.2 4.2 0.4 0.5 6.6 3.4 0.5 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.2 7.5 9.0 0.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 39.0 19.8 43.6 33.8 28.4 62.4 9.3 16.9 26.2 13.0 8.1 8.6 19.4 15.2 49.1 32.1 5.9 9.0 24.5 0.5 0.6 0.5 0.8 0.4 1.0 1.9 1.0 1.6 1.0 1.2 2.3 2.9 3.2 21.6 0.3 77.8 4.2 0.5 0.0 0.0 0.2 1.9 3.2 0.4 7.2 1.3 0.0 0.0 0.2 256.1 0.5 0.0 0.0 9.1 0.2 0.4 2.1 0.0 6.6 0.0 0.0 0.3 2.3 6.6 0.5 317.8 0.0 3.9 1.4 62.8 0.0 0.0 0.6 0.0 112.5 73.1 1.4 0.6 88.6 3.6 4.7 90.9 0.0 319.3 0.0 0.1 0.0 0.0 0.0 25.6 0.2 0.1 0.3 0.7 0.2 0.0 0.9 2.0 0.1 0.1 0.7 5.3 0.4 192.8 0.9 0.4 0.2 GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316820 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 32.8;vagina: 23.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 139.2;Basal respiratory cells: 150.0;Suprabasal keratinocytes: 68.2;Syncytiotrophoblasts: 205.0;Urothelial cells: 211.4" "Group enriched" "Detected in many" 6 "cervical cancer: 44.1;head and neck cancer: 40.1;lung cancer: 22.0;urothelial cancer: 23.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 110.8;CAPAN-2: 40.8;HaCaT: 90.6;HBEC3-KT: 116.7;hTCEpi: 152.8;hTERT-HME1: 62.2;RT4: 46.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" No No "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: AB_2685656" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (4.07e-3)" "unprognostic (8.60e-2)" "unprognostic (1.28e-2)" "unprognostic (4.61e-3)" "unprognostic (3.28e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (4.62e-6)" "unprognostic (8.64e-2)" "unprognostic (1.50e-3)" "unprognostic (3.66e-4)" "unprognostic (8.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.1 0.8 10.0 2.9 0.0 0.0 0.0 3.2 35.9 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.6 0.0 4.3 0.0 0.0 13.7 5.5 0.1 32.8 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.5 0.0 0.0 12.4 13.2 23.8 0.4 110.8 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.9 0.2 0.0 40.8 0.0 0.0 0.0 0.6 90.6 0.0 116.7 1.1 0.0 0.1 0.0 1.1 0.0 0.8 0.0 0.0 0.0 152.8 0.1 62.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.1 6.1 0.0 0.0 0.0 3.8 46.7 0.0 0.0 19.0 0.5 0.0 3.1 0.4 0.1 0.0 0.0 10.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.1 1.0 0.0 59.3 139.2 150.0 46.7 0.0 2.8 1.8 0.1 0.0 49.9 3.7 0.0 59.0 0.4 0.0 0.0 1.2 0.7 3.3 0.0 1.5 0.0 0.0 1.1 0.7 8.7 1.1 0.0 2.4 1.3 0.0 0.0 0.0 4.2 0.0 0.4 0.0 28.5 0.0 3.6 0.1 0.0 0.6 10.6 0.0 0.0 0.0 0.0 1.0 0.0 12.9 0.0 0.0 0.0 60.6 0.0 0.1 19.6 0.0 0.0 0.0 4.1 0.0 0.0 52.7 68.2 205.0 0.9 0.0 0.0 211.4 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 197.7;Late spermatids: 269.9;Oligodendrocytes: 171.0" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Cell line enhanced" "Detected in many" "EFO-21: 92.5;HHSteC: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 25.3 7.0 249.1 4.4 428.3 0.1 19.6 365.2 263.4 12.8 13.1 8.1 5.7 13.1 14.8 8.1 20.1 15.3 40.7 245.8 278.4 22.4 3.2 5.8 7.8 379.4 327.1 22.6 21.7 45.9 14.1 15.7 333.0 9.6 2.4 17.4 40.1 17.7 72.7 7.5 11.1 7.5 262.7 2.5 41.3 34.0 315.0 3.2 13.8 73.8 3.4 12.8 8.6 490.3 1.2 29.9 29.0 5.2 29.3 2.0 5.3 0.3 7.4 2.9 1.8 28.0 1.0 0.0 92.5 1.0 18.9 1.6 21.6 0.2 1.7 0.2 8.6 0.0 0.1 0.0 60.3 0.0 0.0 2.5 0.0 4.9 0.0 7.9 14.3 0.7 6.6 0.6 6.7 1.5 0.1 0.1 31.8 0.0 15.6 8.9 0.0 0.2 1.1 13.8 22.9 1.9 3.6 1.9 27.2 9.1 0.1 0.6 2.9 0.0 3.5 14.4 0.8 0.4 0.1 0.3 1.4 0.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 249.1 428.3 365.2 263.4 245.8 278.4 379.4 327.1 333.0 262.7 315.0 490.3 71.4 0.0 3.0 75.4 1.2 1.3 5.3 2.6 9.1 30.7 22.5 16.3 15.7 40.0 7.2 31.3 0.0 5.0 0.3 0.2 1.9 65.3 197.7 4.1 20.7 44.8 0.0 0.0 2.4 64.5 1.4 14.8 31.6 13.7 0.0 0.4 9.3 0.2 4.1 0.0 13.5 0.0 38.7 1.6 2.6 269.9 23.9 2.2 16.0 7.5 1.0 24.8 0.0 51.8 171.0 72.8 0.0 26.7 1.3 12.3 0.0 0.3 3.3 6.0 13.1 3.3 13.0 4.9 1.6 2.4 1.7 2.5 0.8 7.0 0.2 1.6 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46549044-46555530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.5;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Distal enterocytes: 30.4;Exocrine glandular cells: 20.2;Intestinal goblet cells: 30.8;Late spermatids: 20.6;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 10.2;A549: 13.1;SiHa: 3.7;SK-BR-3: 12.0" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" 0.1 0.0 1.7 0.6 1.6 0.0 0.9 5.9 2.1 0.9 0.4 6.2 3.6 0.0 0.0 4.4 0.3 0.2 0.0 0.6 6.7 5.7 0.3 10.5 0.0 5.5 4.9 0.1 5.7 2.1 4.2 0.0 5.7 1.9 3.4 0.1 2.8 1.1 0.1 17.4 8.0 0.1 1.8 0.0 5.1 3.0 9.7 0.0 3.4 0.0 0.5 0.6 2.0 1.0 10.2 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.2 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.0 1.7 0.3 0.3 0.1 3.7 12.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.9 2.1 0.6 6.7 5.5 4.9 5.7 1.8 9.7 1.0 0.0 19.2 3.7 0.0 0.0 1.7 2.8 1.9 2.8 0.3 1.4 1.0 0.2 7.2 2.1 3.7 0.0 0.0 0.0 30.4 0.0 11.3 9.3 0.0 0.0 0.1 6.6 0.0 0.7 20.2 0.0 0.1 3.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.9 30.8 0.0 0.0 0.3 20.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.6 13.1 0.4 0.0 2.1 21.7 4.0 1.8 0.1 0.0 0.0 0.2 2.9 0.8 2.4 6.1 0.0 0.1 0.0 7.3 1.3 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.8;choroid plexus: 91.8;retina: 96.7" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Inhibitory neurons: 102.8;Oligodendrocyte precursor cells: 95.0;Rod photoreceptor cells: 92.3;Theca cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 7.0" "Group enriched" "Detected in many" 4 "A549: 62.4;HDLM-2: 168.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" 1.8 258.8 22.5 4.3 27.4 18.6 1.1 80.1 52.3 0.9 91.8 1.6 34.6 1.1 9.4 0.6 3.6 12.1 15.0 55.6 19.4 15.5 1.5 2.6 5.4 25.7 20.1 15.2 2.4 0.7 16.6 5.0 24.2 1.1 1.1 96.7 1.9 2.0 3.4 0.5 25.2 1.2 9.4 3.6 11.4 16.8 33.5 6.6 4.9 2.2 3.5 1.2 0.8 26.1 0.1 62.4 3.5 0.1 0.3 0.7 9.5 20.5 14.6 4.1 1.8 2.6 0.4 3.8 10.4 10.1 6.8 0.0 6.2 0.0 4.3 168.5 5.0 0.0 28.3 0.7 0.0 22.1 0.0 1.0 0.1 7.1 0.0 5.2 1.8 1.6 0.0 0.2 3.7 0.5 3.8 7.2 7.6 28.3 23.0 10.8 9.8 6.8 0.2 0.0 20.0 16.3 4.9 0.5 0.1 8.1 0.5 12.0 12.3 23.8 3.2 4.2 1.0 0.0 0.0 0.0 4.6 20.5 1.1 0.0 1.2 0.4 0.4 0.7 0.2 0.0 1.5 1.2 1.7 0.0 0.2 0.2 0.1 1.6 0.7 7.0 0.7 0.5 22.5 27.4 80.1 52.3 55.6 19.4 25.7 20.1 24.2 9.4 33.5 26.1 1.4 0.0 0.5 94.7 0.6 0.0 0.0 0.1 1.2 44.3 1.1 1.0 5.7 21.5 0.2 5.5 114.7 6.9 17.9 0.1 3.9 0.7 9.6 1.6 0.6 1.0 0.0 0.0 120.7 0.4 3.7 1.6 16.3 0.9 0.0 41.9 0.7 0.0 2.6 45.4 102.8 1.8 0.0 3.8 2.6 2.7 0.6 7.5 0.0 37.5 2.5 23.4 0.0 95.0 5.5 3.9 1.3 0.7 2.4 0.1 17.3 8.9 0.4 92.3 0.0 3.0 4.2 3.9 1.9 0.1 0.4 2.5 7.2 109.3 1.5 0.0 GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.9;placenta: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 70.5;Cytotrophoblasts: 106.2;Extravillous trophoblasts: 29.5;Syncytiotrophoblasts: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 165.5;SK-BR-3: 75.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nuclear speckles" Cytosol "HPA029435: AB_10601811" "unprognostic (5.70e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.24e-1)" "unprognostic (9.51e-3)" "unprognostic (2.95e-1)" "unprognostic (9.96e-2)" "unprognostic (3.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (7.29e-2)" 0.0 0.0 2.1 0.5 1.7 0.0 10.2 2.0 1.3 1.9 2.1 1.2 1.0 0.4 35.9 1.1 5.8 0.3 0.1 2.2 3.9 3.2 0.0 15.0 0.4 6.5 13.1 0.1 0.5 0.1 0.7 48.7 10.1 1.3 0.8 0.9 2.1 5.2 0.0 2.5 3.3 0.2 2.6 0.2 0.8 0.4 3.0 0.2 8.9 0.0 0.4 0.3 0.7 2.0 2.1 0.0 0.1 0.0 0.0 0.0 165.5 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.0 0.0 1.2 0.0 10.0 0.2 0.0 0.2 0.3 0.1 0.0 1.2 0.0 0.0 0.1 2.1 0.0 7.5 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.2 0.1 1.7 0.1 0.3 75.8 0.1 5.5 3.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 2.0 1.3 2.2 3.9 6.5 13.1 10.1 2.6 3.0 2.0 0.1 70.5 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.3 0.0 0.0 7.4 3.7 0.0 106.2 0.1 0.0 0.0 0.1 0.0 14.0 0.2 0.2 0.0 0.0 0.0 0.0 29.5 0.8 0.0 0.7 1.3 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 10.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 147.1 0.3 0.1 0.0 0.0 GRAMD2B "FLJ21313, GRAMD3, NS3TP2" ENSG00000155324 "GRAM domain containing 2B" Q96HH9 5 126360132-126496494 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 73.2;Club cells: 45.8;Endometrial ciliated cells: 51.8;Endometrial stromal cells: 49.0;Extravillous trophoblasts: 46.5;Glandular and luminal cells: 153.2;Respiratory ciliated cells: 48.8;Syncytiotrophoblasts: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.9;MAIT T-cell: 2.8;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.3;myeloid DC: 1.7;naive CD4 T-cell: 3.0;naive CD8 T-cell: 1.8;NK-cell: 1.1;plasmacytoid DC: 4.3;T-reg: 2.4" "Group enriched" "Detected in many" 6 "dendritic cells: 4.3;NK-cells: 1.1;T-cells: 3.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 114.1;CAPAN-2: 73.6;fHDF/TERT166: 75.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009678, HPA010095" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA009678: AB_2112580, HPA010095: AB_1849952" "unprognostic (2.34e-1)" "unprognostic (4.01e-1)" "unprognostic (4.63e-2)" "unprognostic (3.42e-2)" "unprognostic (6.82e-2)" "unprognostic (1.95e-2)" "unprognostic (6.76e-2)" "unprognostic (3.84e-2)" "unprognostic (9.90e-2)" "unprognostic (7.42e-2)" "unprognostic (2.09e-2)" "unprognostic (3.78e-1)" "unprognostic (2.20e-3)" "unprognostic (3.56e-3)" "unprognostic (2.39e-1)" "unprognostic (9.24e-2)" "unprognostic (1.12e-2)" 12.8 16.0 56.5 6.9 57.1 1.6 38.7 54.1 55.1 32.2 47.7 28.6 29.6 29.4 15.5 8.9 34.3 10.9 11.7 49.4 54.6 32.9 24.4 11.3 7.4 61.3 64.7 30.3 8.9 8.7 10.0 24.7 55.2 16.9 29.8 6.6 23.1 23.7 3.8 27.3 36.0 22.1 64.9 6.1 16.4 4.1 54.0 13.2 40.4 5.6 11.2 13.8 16.3 60.5 66.1 3.7 3.0 14.6 62.4 21.5 19.4 71.2 114.1 28.7 37.2 2.6 73.6 0.0 26.4 75.4 0.7 17.5 0.9 27.6 30.9 6.1 4.8 3.1 8.2 3.9 14.2 0.0 2.3 34.6 10.4 29.2 9.4 36.4 0.2 0.0 0.0 0.0 50.7 6.7 0.0 0.9 3.1 13.7 4.6 1.3 17.6 14.3 38.8 69.1 1.1 0.1 11.9 6.0 21.2 12.8 22.9 4.2 6.6 6.6 2.1 11.6 12.7 3.9 3.5 0.1 1.4 0.0 19.2 0.2 0.4 0.0 2.9 0.4 2.8 0.5 1.6 2.3 1.7 0.2 3.0 1.8 0.3 1.1 0.3 4.3 2.4 1.2 56.5 57.1 54.1 55.1 49.4 54.6 61.3 64.7 55.2 64.9 54.0 60.5 10.2 16.0 17.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 25.5 73.2 0.0 0.0 45.8 40.5 0.0 32.3 10.0 0.0 23.5 14.1 0.0 51.8 49.0 3.2 0.0 0.0 0.0 8.7 46.5 8.7 0.0 153.2 3.8 4.9 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 2.8 0.0 0.0 18.3 48.8 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 58.6 4.7 2.8 0.0 0.0 GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 184.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 32.6;granulocytes: 146.9;Macrophages: 82.0;NK-cells: 59.8;T-cells: 57.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "gdT-cell: 51.4;MAIT T-cell: 38.2;memory CD4 T-cell: 37.5;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.2;T-reg: 35.0" "Lineage enriched" "Detected in many" 9 "T-cells: 58.2" "Group enriched" "Detected in some" 4 "HEL: 45.7;JURKAT: 175.8;K-562: 44.8;MOLT-4: 122.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 290000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: AB_1079021" "unprognostic (1.96e-4)" "unprognostic (1.82e-4)" "unprognostic (4.19e-2)" "unprognostic (8.91e-4)" "unprognostic (2.92e-2)" "unprognostic (5.56e-5)" "unprognostic (1.27e-2)" "unprognostic (8.41e-3)" "unprognostic (4.69e-2)" "unprognostic (9.29e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-2)" "unprognostic (1.75e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (8.06e-2)" 1.2 0.7 0.2 7.9 0.2 10.3 2.0 0.2 0.3 1.5 0.5 2.2 3.6 0.8 0.5 1.2 0.7 2.6 1.1 0.2 0.3 0.6 1.2 4.4 15.7 0.6 0.3 0.2 0.4 0.1 0.3 0.6 0.5 1.6 2.3 0.3 1.7 0.7 0.4 1.1 4.5 0.9 0.5 9.3 3.8 1.9 0.4 184.8 0.8 0.5 12.9 3.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 45.7 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.2 0.3 0.0 175.8 44.8 0.0 0.0 0.0 122.8 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 6.3 0.7 0.1 51.4 0.3 38.2 3.1 37.5 56.2 1.2 5.2 31.3 58.2 6.6 5.4 0.3 0.8 35.0 74.9 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.3 0.5 0.5 0.4 0.7 1.1 0.0 6.7 0.3 8.2 1.7 0.0 0.0 0.0 0.6 1.1 0.8 1.0 2.8 0.0 0.0 0.0 0.0 18.3 0.1 0.0 0.4 4.8 0.3 0.1 0.8 1.2 32.6 1.3 0.2 0.0 0.6 0.0 0.1 146.9 0.2 2.5 2.3 0.2 0.0 1.2 0.6 0.0 1.9 4.6 2.9 0.3 82.0 1.8 1.0 6.8 0.3 59.8 2.5 1.0 0.0 0.3 0.4 6.3 0.4 0.0 0.4 0.0 0.0 0.0 0.5 0.9 4.4 2.1 0.1 1.1 0.1 57.1 0.0 0.1 0.3 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GRWD1 "GRWD, RRB1, WDR28" ENSG00000105447 "Glutamate rich WD repeat containing 1" Q9BQ67 19 48445841-48457022 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042643, HPA055680" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042643: AB_10795510, HPA055680: AB_2682884" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (4.99e-2)" "unprognostic (1.00e-1)" "unprognostic (3.46e-1)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.71e-2)" "unprognostic (5.68e-2)" "unprognostic (2.69e-2)" "unprognostic (7.70e-2)" "unprognostic (2.83e-2)" "unprognostic (8.10e-2)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (2.02e-1)" "unprognostic (5.07e-2)" 16.0 13.7 6.3 14.0 5.8 14.0 14.4 7.0 6.9 13.7 7.2 11.5 13.1 16.1 4.2 18.2 13.0 8.6 13.6 6.2 6.7 13.0 16.3 10.9 16.0 6.9 7.4 13.7 18.6 13.0 8.6 11.4 7.4 12.2 6.5 3.7 12.7 8.9 28.4 17.5 10.9 8.6 5.6 14.1 13.8 7.4 8.7 11.5 11.8 14.5 10.6 14.6 13.5 7.3 58.3 148.9 25.0 47.3 20.2 19.8 21.6 44.9 20.8 62.2 51.8 84.0 42.4 83.4 37.8 28.7 35.0 48.8 62.7 67.9 24.9 63.8 86.5 78.2 48.6 60.4 23.0 71.9 47.8 23.8 37.0 58.9 29.4 14.3 31.5 43.8 107.3 50.1 27.0 59.1 75.1 180.1 68.1 63.8 43.2 92.9 28.3 58.5 26.4 70.4 56.2 32.1 51.3 71.0 22.4 15.4 34.6 36.5 35.2 57.9 49.1 25.9 107.1 50.6 126.8 78.3 19.7 64.8 69.0 0.3 24.8 3.3 41.5 40.7 46.4 44.4 37.1 41.0 40.9 44.8 42.6 40.3 2.0 41.6 32.4 29.7 36.3 37.4 6.3 5.8 7.0 6.9 6.2 6.7 6.9 7.4 7.4 5.6 8.7 7.3 17.3 3.2 17.5 1.0 26.8 46.3 31.7 18.6 23.3 13.4 16.0 13.7 7.1 14.3 14.3 12.9 0.0 41.4 15.1 14.4 23.5 29.0 3.8 13.1 20.5 19.1 19.2 28.8 1.6 18.2 39.7 18.1 13.3 14.3 19.7 16.8 13.6 18.5 24.4 21.9 3.9 14.5 14.2 11.1 14.3 19.4 17.1 11.4 28.4 2.8 25.3 6.1 19.6 3.0 2.6 22.4 6.5 12.4 28.5 24.2 6.8 18.8 16.8 15.7 19.7 22.7 20.4 9.4 34.3 20.5 40.6 35.0 17.9 26.3 17.1 24.0 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 GSKIP C14orf129 ENSG00000100744 "GSK3B interacting protein" Q9P0R6 14 96363452-96387288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 166.1;Early spermatids: 384.9;Late spermatids: 321.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043054, HPA046782" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus, Vesicles" Nucleoli "HPA043054: AB_2678293, HPA046782: AB_2679803" "unprognostic (3.48e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (6.23e-3)" "unprognostic (1.11e-1)" "unprognostic (9.35e-2)" "unprognostic (1.16e-3)" "unprognostic (6.82e-2)" "unprognostic (2.84e-1)" "unprognostic (8.74e-3)" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" 11.4 13.1 13.6 17.5 16.7 16.2 13.2 14.7 16.7 10.4 10.9 60.4 48.3 10.6 11.3 41.0 10.9 14.2 11.0 15.7 14.8 16.4 23.3 9.7 19.6 12.9 12.0 6.7 9.9 9.5 8.1 13.8 13.3 13.9 54.6 67.8 12.1 9.9 12.7 14.5 56.6 15.9 13.9 11.8 23.3 48.7 13.7 11.1 10.3 10.6 22.4 21.1 16.2 14.9 21.9 30.5 33.6 23.1 25.2 29.1 56.6 39.7 30.7 26.2 28.8 22.7 36.6 20.9 23.6 30.4 15.9 23.8 22.1 24.2 37.9 49.9 21.1 8.8 16.1 17.5 23.4 23.1 14.5 23.2 37.7 33.1 32.7 20.1 34.6 23.5 19.2 18.7 33.6 53.5 17.0 18.6 37.3 33.9 38.3 16.7 31.4 19.3 61.5 79.9 11.8 38.4 44.8 41.6 34.9 33.7 31.9 14.3 37.8 12.0 15.1 25.6 12.8 21.7 67.0 17.8 30.6 16.4 19.6 64.4 20.9 47.0 27.7 24.3 42.8 38.3 37.6 32.4 21.2 33.1 37.0 34.5 40.9 37.5 33.6 17.9 66.6 28.6 13.6 16.7 14.7 16.7 15.7 14.8 12.9 12.0 13.3 13.9 13.7 14.9 12.6 12.8 7.4 5.9 24.8 45.2 24.2 27.6 19.9 26.8 18.4 14.5 18.9 14.3 21.7 20.2 41.7 42.7 17.9 166.1 72.4 34.1 384.9 32.3 11.1 17.4 28.1 24.0 14.3 39.4 43.3 12.1 41.8 32.2 19.7 6.6 17.9 17.3 23.6 23.5 10.8 73.0 52.9 19.8 19.6 321.7 8.1 16.8 19.6 5.6 25.2 22.3 16.5 10.6 17.9 39.9 102.9 7.9 22.6 37.4 81.8 47.4 28.6 104.0 19.7 6.5 16.5 40.0 34.1 35.7 65.9 119.6 24.4 7.9 69.1 43.7 GSX1 "Gsh-1, GSH1" ENSG00000169840 "GS homeobox 1" Q9H4S2 13 27792483-27794768 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "brain: 7.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "glioma: 3.9" "Region enriched" "Detected in some" 4 "hypothalamus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA047096 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA047096: AB_2679929" "unprognostic (1.62e-1)" 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.3 0.3 7.5 0.4 0.2 0.2 0.2 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379572-6393981 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 228.3;Late spermatids: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Cell Junctions" "HPA022793: AB_1857946, HPA028707: AB_2672745, HPA070752: AB_2732163" "unprognostic (1.30e-2)" "unprognostic (6.05e-3)" "unprognostic (2.00e-1)" "prognostic favorable (8.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.99e-2)" "unprognostic (6.45e-3)" "unprognostic (6.96e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.92e-2)" "unprognostic (4.25e-1)" 35.0 38.1 36.7 34.0 38.4 71.0 34.2 43.6 43.0 48.8 30.2 41.2 40.5 48.5 25.9 46.0 44.8 36.1 32.8 39.1 35.8 37.6 30.0 31.5 43.5 34.4 34.3 73.6 57.5 42.6 49.8 26.8 34.6 39.5 23.3 24.9 43.8 31.7 36.8 36.8 39.2 25.1 30.1 36.4 43.9 68.3 36.1 37.1 49.6 22.6 29.8 37.3 41.0 36.1 115.6 97.1 62.0 100.9 46.5 73.1 47.3 81.7 84.7 112.0 106.0 104.4 48.5 76.3 111.9 67.2 73.5 109.9 69.3 65.6 57.1 106.6 90.1 97.2 60.7 86.9 78.6 107.1 79.5 82.8 78.2 85.5 64.1 86.4 69.0 72.9 115.9 91.7 63.9 96.2 115.4 79.7 108.2 59.7 124.3 101.5 68.0 94.6 67.5 74.2 76.1 99.8 83.0 64.5 95.6 36.4 84.0 94.0 79.8 78.5 62.6 134.0 110.1 153.9 197.2 79.7 98.1 124.9 91.0 10.2 29.7 20.8 26.1 28.4 29.7 32.9 23.5 24.9 23.3 31.6 27.0 24.6 40.1 27.6 30.2 30.3 25.4 19.8 36.7 38.4 43.6 43.0 39.1 35.8 34.4 34.3 34.6 30.1 36.1 36.1 29.2 48.1 56.6 5.2 51.9 24.3 50.2 40.5 53.5 27.6 43.1 34.7 28.9 32.9 58.4 25.8 8.4 46.1 51.6 88.2 21.5 48.5 228.3 70.5 70.7 41.0 30.5 51.7 6.9 50.8 43.0 43.3 51.0 57.4 63.8 32.7 58.9 26.0 60.2 25.2 7.0 53.4 24.4 54.8 25.9 391.6 44.4 42.1 33.8 5.6 66.0 35.6 49.4 3.5 4.9 47.4 66.0 49.7 55.4 29.9 65.3 48.8 83.6 33.5 32.9 44.8 52.9 71.8 38.3 44.9 21.0 54.0 48.3 41.8 54.4 40.6 GTPBP1 "GP-1, HSPC018" ENSG00000100226 "GTP binding protein 1" O00178 22 38705742-38738299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003166, HPA064702" Approved Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 64000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Cytosol" "Nuclear bodies" "HPA003166: AB_10601476, HPA064702: AB_2685329" "unprognostic (1.42e-3)" "unprognostic (5.82e-3)" "unprognostic (1.08e-1)" "unprognostic (1.18e-2)" "unprognostic (1.94e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (3.17e-1)" "unprognostic (3.67e-2)" "unprognostic (1.56e-2)" "unprognostic (2.95e-2)" "unprognostic (2.88e-1)" "unprognostic (5.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.76e-2)" "unprognostic (3.40e-1)" "unprognostic (1.98e-3)" 18.4 19.0 16.5 23.4 19.1 105.4 18.4 20.0 44.3 20.3 20.8 20.5 20.5 20.0 12.1 22.4 22.1 17.7 20.0 18.4 19.3 18.4 17.1 28.9 23.0 19.3 17.0 27.4 22.0 19.2 25.5 16.0 17.0 23.8 17.6 34.7 21.2 15.5 31.7 27.5 22.9 16.6 15.5 28.0 20.4 20.3 16.7 20.0 24.9 19.9 23.0 18.7 19.4 23.9 29.2 10.5 37.4 30.2 12.6 19.7 18.3 27.4 28.7 39.0 33.9 22.0 16.3 27.9 9.8 26.9 17.5 26.6 45.5 28.8 21.6 49.2 32.8 48.7 36.9 16.3 23.9 57.7 24.3 20.3 22.0 31.2 48.7 21.3 24.3 20.2 29.4 56.5 21.8 12.1 32.1 26.1 27.0 16.7 20.8 61.8 38.2 36.7 13.8 23.3 51.0 17.7 33.3 21.0 19.6 16.2 19.0 24.2 26.1 22.3 22.0 16.4 21.2 51.8 18.7 38.5 20.1 29.0 16.9 3.5 3.1 3.9 4.7 4.6 4.2 4.6 3.5 4.9 3.4 3.8 2.5 3.7 7.8 2.3 5.1 1.7 3.3 3.4 16.5 19.1 20.0 44.3 18.4 19.3 19.3 17.0 17.0 15.5 16.7 23.9 17.8 9.6 8.4 7.8 31.8 27.8 36.0 12.7 15.4 32.6 17.5 15.5 11.2 5.7 12.4 12.9 22.9 7.2 35.9 40.3 5.9 13.2 4.5 22.2 14.3 13.1 16.2 35.3 5.5 19.3 7.9 14.5 23.4 26.4 14.0 17.5 13.6 12.4 8.6 20.2 7.9 24.3 16.2 18.4 43.9 5.4 16.1 19.3 10.6 4.7 26.6 13.2 20.6 5.5 15.2 19.9 21.1 19.2 52.8 47.4 29.8 6.1 16.6 41.0 26.3 19.9 14.5 17.2 7.7 19.2 34.2 19.0 31.9 15.5 13.0 51.0 GTPBP4 "CRFG, FLJ10686, FLJ10690, NGB, NOG1" ENSG00000107937 "GTP binding protein 4" Q9BZE4 10 988434-1019932 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039618, HPA056468" Uncertain Supported "Nuclear membrane,Nucleoli,Nucleoli rim" No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" "Nuclear membrane" "HPA039618: AB_10795292, HPA056468: AB_2683141" "unprognostic (2.11e-3)" "unprognostic (3.10e-3)" "unprognostic (7.77e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (3.72e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (8.85e-12)" "unprognostic (9.06e-2)" "unprognostic (1.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.11e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (2.38e-5)" "unprognostic (7.90e-2)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (3.67e-2)" 15.6 19.6 8.0 12.6 8.5 26.9 12.8 8.6 8.7 8.4 9.4 9.5 8.6 11.0 8.8 11.4 9.2 7.9 11.1 8.8 9.5 9.4 10.9 8.5 13.9 9.1 9.4 9.8 11.9 10.3 7.8 10.2 9.1 9.0 10.8 8.9 7.8 8.4 26.6 9.5 8.2 12.2 9.5 9.4 9.2 21.0 9.4 12.0 9.8 14.8 15.6 18.3 8.7 10.1 57.0 49.4 37.1 34.9 27.9 31.1 27.3 52.3 18.8 62.6 53.3 73.2 43.3 87.0 15.2 45.5 21.3 43.6 77.4 52.0 71.2 41.8 50.9 94.7 35.3 45.4 44.5 41.3 47.1 43.1 42.7 72.7 51.6 25.5 34.7 62.9 98.3 33.5 60.1 57.0 62.0 40.3 56.2 77.9 33.8 59.3 35.5 57.6 37.9 37.4 19.3 57.3 37.3 44.7 66.3 36.7 61.8 42.3 32.4 30.3 16.4 71.5 65.2 45.0 86.9 103.5 33.9 43.5 24.9 18.2 9.6 3.6 12.4 16.2 14.3 12.0 11.7 12.6 12.9 11.2 12.7 12.5 1.5 18.4 13.3 8.6 16.6 8.9 8.0 8.5 8.6 8.7 8.8 9.5 9.1 9.4 9.1 9.5 9.4 10.1 36.2 57.7 74.3 5.9 41.8 62.7 100.0 52.8 35.3 26.1 28.1 27.4 32.6 21.5 83.5 29.5 18.8 50.3 37.4 18.4 33.2 57.7 70.9 46.8 51.9 49.2 22.1 37.4 9.3 44.1 54.9 48.9 33.6 78.8 66.9 40.1 20.0 27.5 34.7 23.5 8.9 29.9 40.7 26.0 24.4 20.9 24.8 33.1 23.2 8.4 39.5 26.5 22.6 6.0 10.2 72.2 17.3 29.3 37.0 84.7 10.6 25.6 55.8 32.7 19.7 58.5 51.4 88.7 84.9 47.0 67.2 95.4 37.5 57.7 32.6 102.6 GVQW3 ENSG00000179240 "GVQW motif containing 3" Q3ZCU0 11 76381303-76414619 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 14.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.9;Distal tubular cells: 9.8;granulocytes: 3.8;Granulosa cells: 7.0;Proximal tubular cells: 6.7;Theca cells: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057405 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Centrosome" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Centrosome" "Endoplasmic reticulum" "HPA057405: AB_2683429" "unprognostic (8.90e-2)" "unprognostic (1.16e-1)" "unprognostic (8.27e-2)" "unprognostic (1.92e-1)" "unprognostic (9.04e-3)" "unprognostic (8.56e-2)" "unprognostic (8.87e-2)" "unprognostic (2.91e-2)" "unprognostic (7.28e-3)" "unprognostic (2.21e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (4.05e-4)" "unprognostic (7.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.28e-2)" "unprognostic (2.13e-1)" 1.1 1.5 1.5 1.4 1.6 1.1 1.9 3.2 2.1 1.7 4.4 1.3 1.4 1.8 1.9 0.4 2.0 0.7 1.0 1.4 0.8 1.4 0.7 0.9 1.9 0.5 0.1 2.2 6.5 1.0 2.4 0.8 0.6 1.2 1.5 14.2 1.9 0.8 1.1 1.4 1.3 0.9 0.0 1.7 1.4 3.4 1.2 2.4 1.9 0.6 1.6 0.9 1.3 1.5 1.1 1.2 4.4 3.2 1.2 1.6 1.5 0.6 0.5 1.1 1.1 3.0 2.0 3.6 1.2 0.5 1.3 2.6 1.9 0.8 1.9 2.0 1.2 1.9 5.0 1.3 0.7 2.5 1.2 0.7 1.2 1.4 0.8 1.0 0.9 4.9 1.2 2.3 0.4 1.3 2.4 3.8 0.9 0.9 1.4 3.7 2.9 1.9 0.7 0.8 6.5 2.9 1.2 0.7 0.7 1.7 2.1 0.8 0.6 2.1 2.2 3.2 0.7 2.1 1.6 4.6 0.8 1.7 1.1 1.5 0.3 0.4 0.4 0.2 0.3 0.5 0.6 0.5 0.2 0.6 0.6 0.6 1.0 0.8 0.2 0.3 0.8 0.2 1.5 1.6 3.2 2.1 1.4 0.8 0.5 0.1 0.6 0.0 1.2 1.5 2.1 0.0 3.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 2.3 0.0 0.0 2.5 1.8 0.0 1.1 1.7 0.0 9.8 1.2 0.0 2.4 2.5 0.8 0.0 0.0 0.0 0.6 0.6 1.4 0.0 0.6 3.8 7.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 6.7 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.9 5.5 0.0 0.0 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 GYPA "CD235a, GPA, MN, MNS" ENSG00000170180 "Glycophorin A (MNS blood group)" P02724 4 144109303-144140751 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "bone marrow: 156.3" "Cell type enriched" "Detected in some" 350 "Erythroid cells: 1995.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 203 "HEL: 149.1;K-562: 37.7" "CAB002658, HPA014811" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 15000000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane, Cytosol" "CAB002658: , HPA014811: AB_1849827" "unprognostic (1.60e-1)" "unprognostic (2.47e-2)" 0.1 0.1 0.1 0.0 0.1 156.3 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.3 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.7 0.0 0.0 0.0 0.0 1995.6 2.4 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 1.7 0.0 0.0 0.9 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 H1-10 "H1FX, H1X, MGC15959, MGC8350" ENSG00000184897 "H1.10 linker histone" Q92522 3 129314771-129316286 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1004.3" "Cell type enhanced" "Detected in some" "Adipocytes: 188.4;Cytotrophoblasts: 66.8;dendritic cells: 73.2;Extravillous trophoblasts: 114.2;Hofbauer cells: 93.4;Plasma cells: 148.6;Syncytiotrophoblasts: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 937.8" "Low region specificity" "Detected in all" "CAB012235, HPA040099, HPA068431" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB012235: , HPA040099: AB_2676846, HPA068431: " "unprognostic (1.01e-2)" "unprognostic (1.12e-2)" "unprognostic (4.13e-2)" "unprognostic (8.48e-2)" "unprognostic (6.94e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-2)" "unprognostic (1.46e-2)" "unprognostic (1.16e-1)" "unprognostic (5.51e-2)" "unprognostic (5.28e-3)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" "unprognostic (2.85e-1)" "unprognostic (3.24e-1)" "unprognostic (2.50e-2)" 121.4 54.7 39.9 42.6 43.9 1004.3 145.0 60.6 68.6 162.4 25.2 125.0 44.6 143.1 9.2 107.8 142.2 13.9 82.0 43.1 48.4 162.7 100.1 115.8 44.3 29.5 26.0 168.9 100.0 30.1 112.6 25.4 25.1 124.5 11.9 13.9 98.7 20.8 110.7 258.4 106.7 13.2 27.8 127.7 115.7 40.9 38.2 131.5 94.4 12.3 18.3 130.9 140.7 46.4 141.8 73.4 135.8 59.3 13.6 16.1 129.1 60.5 43.5 70.4 74.3 44.5 75.5 17.8 65.5 21.6 47.2 139.1 57.3 39.0 10.8 129.4 111.7 53.8 55.5 61.1 57.3 62.6 14.1 32.4 51.9 28.7 64.7 32.0 40.7 241.7 83.7 308.5 10.0 147.9 290.9 124.1 127.2 25.8 81.6 207.4 58.1 170.9 22.1 29.1 216.0 250.1 64.1 31.7 196.3 26.1 124.1 125.1 40.9 54.4 283.5 53.5 51.2 937.8 385.2 156.9 44.5 58.6 61.1 0.5 5.5 17.8 4.4 4.2 4.0 5.7 6.7 5.2 7.9 5.3 8.4 4.3 1.2 5.2 3.9 11.4 6.1 2.4 39.9 43.9 60.6 68.6 43.1 48.4 29.5 26.0 25.1 27.8 38.2 46.4 188.4 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 66.8 73.2 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 114.2 46.9 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.1 0.0 0.0 0.0 0.0 68.4 17.6 0.0 0.0 0.0 HAND1 "bHLHa27, eHand, Hxt, Thing1" ENSG00000113196 "Heart and neural crest derivatives expressed 1" O96004 5 154474972-154478227 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 24.3;intestine: 66.1" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 15.2" "Cancer enriched" "Detected in some" 5 "testis cancer: 2.8" "Region enriched" "Detected in single" 4 "thalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "SH-SY5Y: 119.5;SuSa: 212.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040925, HPA075313" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA040925: AB_10796563, HPA075313: " "unprognostic (2.37e-2)" "unprognostic (8.29e-2)" "unprognostic (2.46e-3)" "unprognostic (7.23e-2)" "unprognostic (5.21e-2)" "unprognostic (6.38e-3)" 0.2 4.7 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 3.7 0.0 0.0 0.0 0.0 0.5 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 14.3 12.3 0.0 0.0 0.0 0.3 1.5 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 119.5 0.0 0.0 0.0 212.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 15.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.6 1.7 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.1 1.1 0.0 0.0 0.2 0.0 HAUS2 "C15orf25, CEP27, FLJ10460, HsT17025" ENSG00000137814 "HAUS augmin like complex subunit 2" Q9NVX0 15 42548828-42569994 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039965 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" Centrosome "HPA039965: AB_10673025" "unprognostic (5.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.36e-1)" "unprognostic (6.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-3)" "unprognostic (1.47e-3)" "unprognostic (1.62e-2)" "unprognostic (2.24e-1)" "unprognostic (2.17e-1)" "unprognostic (1.17e-3)" "unprognostic (1.33e-1)" "unprognostic (6.81e-3)" "unprognostic (4.54e-2)" "unprognostic (2.58e-1)" "unprognostic (3.22e-1)" "unprognostic (2.62e-3)" 7.9 5.7 5.5 5.8 5.8 36.5 7.5 5.8 9.5 4.7 4.2 5.8 4.8 6.0 5.5 6.4 4.7 4.6 5.8 6.2 5.8 5.3 5.4 7.0 8.1 6.1 5.6 5.4 6.6 4.5 4.2 6.4 6.2 4.2 5.9 5.4 5.0 3.8 7.2 6.2 5.4 6.7 5.8 5.4 4.9 5.0 5.8 8.9 5.1 5.8 7.9 7.0 4.7 7.6 23.6 12.0 21.5 13.7 10.9 12.3 20.3 22.9 13.9 21.8 17.1 24.5 11.8 13.8 11.1 13.4 18.6 34.6 23.7 15.2 21.5 19.4 13.3 20.0 19.7 19.0 15.6 34.2 14.5 10.6 11.1 16.2 17.7 9.2 22.0 19.2 36.2 17.5 21.3 14.1 21.4 28.5 16.8 31.9 15.3 27.9 26.4 15.0 12.6 16.4 17.8 14.8 23.2 20.6 13.2 15.6 18.7 22.4 17.1 28.7 21.4 39.0 43.8 18.7 61.1 40.0 18.5 38.0 21.6 4.0 4.3 3.9 4.4 5.3 4.5 6.0 4.4 3.7 3.9 5.1 3.3 4.5 1.9 2.9 7.5 4.5 5.2 2.8 5.5 5.8 5.8 9.5 6.2 5.8 6.1 5.6 6.2 5.8 5.8 7.6 17.5 12.8 14.4 5.5 19.4 13.6 20.9 10.9 18.2 7.8 8.6 8.0 4.2 14.3 11.6 3.7 16.7 14.5 17.7 7.1 3.9 14.2 35.2 10.9 12.3 14.6 17.3 31.1 11.6 16.5 27.6 12.9 12.2 10.4 24.6 9.0 7.9 9.7 21.7 16.8 9.3 10.6 8.2 18.5 23.6 7.3 11.1 19.0 1.8 9.4 19.6 9.7 10.3 11.6 10.4 18.8 11.2 11.3 20.1 20.2 8.7 13.3 15.8 16.3 19.7 16.5 12.4 34.0 9.6 23.2 15.3 13.4 21.1 14.0 10.8 17.1 HAUS3 "C4orf15, dgt3, IT1, MGC4701" ENSG00000214367 "HAUS augmin like complex subunit 3" Q68CZ6 4 2078998-2242276 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040649, HPA048190" Approved Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle,Mitochondria" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040649: AB_2677060, HPA048190: AB_2680308" "unprognostic (4.22e-2)" "unprognostic (1.50e-1)" "unprognostic (6.30e-2)" "unprognostic (2.87e-1)" "unprognostic (2.26e-1)" "unprognostic (2.57e-3)" "unprognostic (7.63e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (2.79e-2)" "unprognostic (2.15e-2)" "unprognostic (2.79e-1)" "unprognostic (4.40e-2)" "prognostic favorable (4.78e-5)" 9.6 8.6 3.5 7.5 3.5 27.5 8.9 9.0 4.6 8.1 1.9 8.3 6.5 7.3 4.9 8.0 7.2 4.2 5.8 3.4 3.2 6.2 7.4 9.0 10.2 3.4 3.4 7.3 10.5 4.0 5.6 6.5 3.3 8.5 5.3 5.8 8.5 4.5 7.4 8.9 9.2 4.7 2.3 12.0 9.0 10.7 3.4 8.6 7.4 4.6 8.3 7.1 7.7 4.3 9.8 4.7 14.2 13.0 5.5 8.5 12.8 14.3 6.0 12.7 10.6 9.5 12.5 18.9 6.5 5.7 14.3 9.3 11.9 7.2 15.9 6.8 6.9 12.5 13.1 7.0 4.5 11.6 11.2 4.3 10.2 11.0 5.8 6.6 10.3 8.8 22.0 21.2 12.5 5.4 19.6 19.5 11.2 8.5 12.3 13.9 12.4 10.4 6.3 6.7 18.4 10.0 10.1 7.6 8.4 10.5 15.7 7.8 8.5 18.1 7.8 11.1 17.0 11.2 10.6 16.9 8.8 16.8 12.0 9.6 4.2 12.2 7.9 5.8 10.1 5.5 8.2 8.9 3.8 9.1 9.5 8.9 4.7 10.7 6.9 6.8 12.0 6.6 3.5 3.5 9.0 4.6 3.4 3.2 3.4 3.4 3.3 2.3 3.4 4.3 15.5 3.2 4.8 0.0 15.8 12.6 5.0 6.4 15.4 11.9 9.3 8.8 5.8 7.2 10.3 3.7 12.5 7.3 24.0 3.9 1.9 7.4 11.8 8.9 11.8 9.4 7.2 23.1 0.0 5.7 11.7 9.6 4.6 8.3 13.3 12.1 6.8 3.7 7.2 25.2 0.0 6.4 12.2 5.4 9.3 6.4 9.9 10.4 12.4 0.0 7.9 6.5 16.5 0.0 0.0 5.3 1.8 8.6 22.5 5.1 5.8 2.6 5.4 12.5 0.0 12.3 17.7 34.4 25.3 10.5 7.7 5.1 26.5 10.1 5.8 3.0 HAUS6 "dgt6, FAM29A, FLJ20060, KIAA1574" ENSG00000147874 "HAUS augmin like complex subunit 6" Q7Z4H7 9 19053141-19102904 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 124.9;Spermatocytes: 68.9;Spermatogonia: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 215.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020960, HPA020965" Approved Approved "Nuclear speckles,Centriolar satellite,Cytosol" No No "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" "Centriolar satellite, Cytosol" "Nuclear speckles" "HPA020960: AB_1848393, HPA020965: AB_1848394" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (6.04e-3)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.21e-1)" "unprognostic (2.15e-1)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.13e-5)" "unprognostic (2.52e-1)" "unprognostic (1.68e-1)" "unprognostic (3.13e-2)" "unprognostic (2.03e-1)" 5.3 6.5 5.2 7.9 7.3 17.0 9.2 8.9 7.4 5.4 4.2 5.8 4.0 7.1 6.2 5.2 4.7 5.1 5.2 5.1 6.2 4.1 6.9 4.7 11.4 6.4 6.2 8.2 3.9 6.1 3.0 6.9 6.6 5.6 6.2 9.1 4.5 5.6 4.4 8.1 5.2 7.2 6.1 6.9 4.3 24.0 6.1 15.1 5.3 7.2 10.7 6.2 4.2 9.3 34.7 23.7 46.4 36.3 17.4 20.9 25.1 36.5 25.5 32.7 49.9 12.2 15.4 40.5 13.1 21.1 25.0 14.2 43.3 21.3 50.4 36.8 20.9 215.8 42.1 27.8 11.6 29.0 46.7 13.0 21.5 30.9 66.9 16.9 24.0 40.4 29.8 25.7 37.8 11.3 56.6 49.1 49.9 19.4 23.2 43.3 31.8 16.4 18.0 19.8 27.1 37.3 16.4 15.0 23.6 29.5 11.6 36.1 24.1 29.3 17.7 25.5 42.2 10.2 24.0 39.7 27.3 24.0 13.0 9.8 1.5 1.6 2.8 1.5 3.9 2.3 2.8 3.6 1.5 2.3 3.3 2.9 2.3 5.0 1.4 1.8 3.7 1.7 5.2 7.3 8.9 7.4 5.1 6.2 6.4 6.2 6.6 6.1 6.1 9.3 15.9 19.2 12.5 7.8 14.3 9.7 12.6 8.7 9.1 11.8 9.4 9.3 8.4 5.7 7.2 9.2 10.4 10.5 21.9 5.6 0.0 9.8 124.9 11.8 14.4 11.6 2.4 34.1 10.3 6.1 15.3 9.5 5.6 15.3 11.4 23.8 3.9 6.8 8.2 11.8 10.2 4.6 2.0 5.8 7.7 28.2 11.8 14.5 8.8 10.3 8.2 13.5 12.3 7.1 16.8 9.0 3.4 8.2 17.3 14.6 4.5 3.2 3.6 9.7 6.6 16.2 10.1 68.9 56.0 9.1 8.1 4.9 18.2 11.0 9.4 9.4 HCFC2 HCF-2 ENSG00000111727 "Host cell factor C2" Q9Y5Z7 12 104064531-104106524 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 250.3;Spermatocytes: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006227 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA006227: AB_1079042" "unprognostic (4.22e-3)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (7.66e-2)" "unprognostic (3.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.46e-1)" "unprognostic (1.07e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (2.71e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-3)" "unprognostic (1.16e-2)" "unprognostic (2.24e-1)" "unprognostic (1.19e-2)" "unprognostic (7.23e-2)" 6.3 6.7 3.8 3.6 5.2 2.7 5.1 4.4 5.4 7.4 2.0 9.2 5.2 7.9 5.0 6.2 5.3 5.7 5.1 3.7 4.2 5.7 7.3 4.7 4.6 4.9 5.0 7.8 6.0 6.7 4.1 6.4 4.8 7.2 4.3 8.0 4.5 9.4 9.7 4.4 5.0 7.2 4.7 5.1 5.2 9.5 4.6 5.2 6.9 11.2 3.7 5.9 6.0 6.6 2.0 2.3 2.3 2.0 12.7 12.5 1.7 9.1 4.1 6.8 3.9 1.1 0.9 2.1 3.1 7.1 2.5 2.2 2.9 1.6 7.3 3.5 2.8 2.1 2.3 1.0 8.5 1.7 3.3 7.8 4.3 4.2 3.5 9.8 5.3 3.1 2.5 4.2 12.3 1.8 3.1 4.0 0.5 1.3 4.7 2.5 7.6 1.3 3.1 1.4 3.3 2.5 4.4 3.2 3.5 1.5 5.0 1.9 8.0 10.7 1.4 5.6 3.1 5.3 1.7 1.8 5.1 2.3 4.4 0.4 0.6 0.9 0.8 1.1 0.9 0.5 0.7 0.9 0.7 0.5 0.8 0.9 0.1 0.8 1.8 0.4 0.9 0.5 3.8 5.2 4.4 5.4 3.7 4.2 4.9 5.0 4.8 4.7 4.6 6.6 19.3 12.8 14.1 18.9 10.0 8.0 6.6 5.4 8.6 19.6 6.1 5.0 12.5 1.5 9.6 5.5 20.9 5.0 8.8 7.4 9.8 6.2 250.3 7.9 18.5 14.4 8.4 7.4 31.8 3.3 5.0 16.0 6.6 6.5 17.1 9.8 15.7 11.5 7.4 23.5 33.9 4.7 8.2 11.4 5.7 59.4 21.8 8.6 7.2 16.9 9.3 13.7 7.2 30.7 45.6 3.1 6.0 27.8 12.2 2.7 7.7 8.6 10.4 22.2 13.1 18.7 17.4 130.9 16.4 8.5 7.2 10.8 11.3 17.9 3.8 3.3 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 253.7;lymphoid tissue: 115.6" "Cell type enhanced" "Detected in many" "dendritic cells: 993.2;Hofbauer cells: 571.1;Kupffer cells: 396.6;Langerhans cells: 584.5;Macrophages: 392.7;NK-cells: 1687.0;T-cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 239.9;HL-60: 139.6;HMC-1: 154.3;THP-1: 177.8;U-937: 272.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034435, HPA063026" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" 27.2 9.5 14.0 53.6 13.8 253.7 14.1 13.7 18.5 9.6 16.6 12.7 11.3 8.3 4.7 5.5 9.9 11.5 8.3 13.5 17.0 10.6 14.5 40.3 68.0 18.3 14.7 5.7 6.7 2.5 9.6 24.7 17.6 9.4 8.6 2.2 10.7 8.2 4.2 6.6 28.2 11.2 17.1 115.6 15.4 3.4 18.2 59.6 7.9 3.0 37.8 16.4 8.0 22.2 0.9 0.0 0.3 0.5 1.1 0.0 0.3 1.9 1.1 0.0 0.6 0.8 1.2 26.9 1.7 2.0 0.4 0.9 0.0 0.2 0.0 0.6 0.0 239.9 0.5 0.7 0.9 139.6 154.3 1.6 0.3 0.0 0.0 0.7 0.0 14.8 2.1 33.4 0.4 0.4 16.9 54.7 0.3 0.3 0.7 0.8 0.5 2.0 0.4 0.1 0.9 0.4 1.3 0.7 0.9 0.2 0.5 177.8 0.5 1.4 1.8 0.2 0.2 1.6 1.1 39.5 1.4 272.2 0.3 124.7 725.8 105.8 1583.4 546.1 1172.3 78.6 664.6 1293.3 409.8 51.0 550.6 1108.0 196.1 1290.7 314.4 823.7 629.9 1421.2 14.0 13.8 13.7 18.5 13.5 17.0 18.3 14.7 17.6 17.1 18.2 22.2 12.3 6.4 43.3 0.0 85.3 28.6 1.3 1.7 2.8 0.4 11.4 12.8 1.2 15.7 7.1 9.2 0.0 3.8 993.2 1.8 0.0 2.8 1.3 4.0 2.5 18.3 0.0 84.2 0.1 1.2 4.7 9.5 14.8 5.5 240.4 0.3 21.0 14.3 571.1 1.7 0.1 0.9 2.0 396.6 584.5 3.0 2.1 392.7 44.4 5.6 309.9 0.7 1687.0 0.0 0.1 1.0 1.4 0.0 97.7 0.6 2.0 6.1 5.1 2.2 19.7 4.2 6.2 2.2 4.9 2.7 21.0 6.0 769.9 1.0 2.7 1.2 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 118.9;Syncytiotrophoblasts: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favorable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 30.8 24.7 39.3 10.9 33.5 20.7 28.8 48.8 48.5 40.6 3.3 36.3 11.6 33.2 15.5 45.1 34.1 15.9 53.5 40.4 31.6 24.8 17.4 33.6 14.0 37.6 41.1 45.0 22.5 31.5 48.1 22.6 35.1 29.2 7.3 24.3 22.9 15.1 77.5 71.3 22.9 14.8 22.4 26.4 24.0 19.7 40.0 10.4 30.8 28.6 11.6 29.2 37.0 50.3 8.7 5.5 14.9 3.5 28.2 21.7 53.6 22.8 56.1 11.3 18.1 12.3 9.1 13.5 9.0 54.4 16.5 6.9 17.6 9.8 4.7 21.2 28.7 26.3 18.6 28.6 12.2 8.7 35.7 31.2 16.5 12.8 15.8 19.0 9.3 10.6 20.0 26.5 65.5 6.7 14.3 26.2 16.4 6.7 13.0 54.7 41.6 35.4 1.2 3.8 38.6 20.3 6.7 27.6 31.2 21.8 39.3 49.6 5.1 27.8 17.5 6.6 11.7 43.6 39.7 16.2 16.0 10.7 13.4 11.6 9.2 9.7 5.4 13.5 3.8 7.2 4.3 5.4 11.1 7.5 4.5 4.0 20.9 4.5 16.8 9.7 4.1 7.3 39.3 33.5 48.8 48.5 40.4 31.6 37.6 41.1 35.1 22.4 40.0 50.3 24.0 12.8 13.7 11.1 20.4 29.2 32.3 9.0 26.2 87.8 23.8 21.3 27.1 30.0 11.9 20.2 118.9 21.9 19.6 22.4 21.5 17.2 20.2 17.1 10.7 22.1 46.0 9.3 18.9 8.7 53.1 24.1 10.2 25.1 12.6 47.0 24.3 9.3 22.7 82.4 31.0 14.9 6.1 18.5 17.8 10.0 48.4 29.8 14.2 12.2 16.5 18.9 11.3 14.1 26.2 11.5 16.5 43.6 14.2 41.2 21.5 7.3 12.4 60.4 65.7 31.8 40.1 4.2 32.7 28.1 32.8 218.1 17.0 29.9 11.3 25.3 HEATR5B "DKFZp686P15184, KIAA1414" ENSG00000008869 "HEAT repeat containing 5B" Q9P2D3 2 36968383-37084372 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.3;Inhibitory neurons: 58.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042025, HPA055639" Approved Approved "Nuclear speckles,Vesicles,Cytosol" NA NA 6800 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Vesicles, Cytosol" "HPA042025: AB_10959880, HPA055639: AB_2682870" "unprognostic (3.11e-2)" "unprognostic (1.65e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-2)" "unprognostic (3.70e-2)" "unprognostic (7.75e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-2)" "unprognostic (1.66e-1)" "unprognostic (8.07e-2)" "unprognostic (5.80e-3)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.95e-1)" 9.7 8.8 7.1 15.0 7.1 24.3 14.5 11.7 9.8 9.9 4.9 9.9 10.8 9.5 16.9 11.7 8.1 10.7 9.7 7.4 6.4 9.3 9.3 10.8 31.9 5.8 5.2 9.8 18.2 13.4 6.3 10.2 6.4 11.4 13.5 24.3 14.3 7.7 4.9 18.2 11.5 8.3 3.9 19.0 12.3 9.6 7.0 24.7 11.8 9.4 31.2 10.1 8.5 8.1 16.2 8.1 11.7 17.8 11.9 11.7 14.9 10.1 7.4 9.0 9.1 9.6 10.9 34.6 7.1 8.6 11.9 13.4 11.6 8.2 11.7 17.0 12.6 22.6 11.3 13.1 7.4 24.5 28.5 10.8 11.2 13.0 12.3 9.9 15.5 18.3 21.6 29.8 10.9 9.6 21.5 17.4 7.7 16.7 5.6 20.5 11.9 26.3 10.5 13.8 14.3 12.6 10.6 16.7 7.8 11.7 12.0 7.9 17.2 13.5 7.7 9.9 7.9 18.5 16.2 39.0 11.0 14.3 9.0 18.3 5.0 12.3 7.7 2.8 7.1 9.7 8.5 8.7 9.0 14.0 8.7 7.6 5.2 7.5 4.4 11.2 9.7 5.9 7.1 7.1 11.7 9.8 7.4 6.4 5.8 5.2 6.4 3.9 7.0 8.1 12.9 22.4 10.3 35.9 20.8 9.8 4.2 4.7 6.8 13.0 11.9 8.3 20.8 8.6 7.1 5.5 10.4 7.0 24.4 11.3 1.9 4.6 6.3 14.8 10.0 9.5 5.4 18.7 62.3 6.2 6.2 9.4 25.5 11.1 7.0 9.8 11.7 7.8 6.3 16.8 58.9 8.9 6.1 17.0 15.7 2.6 9.0 13.2 7.2 56.2 9.2 6.5 16.5 57.3 69.7 8.8 6.3 6.4 17.6 5.5 12.7 5.4 12.8 16.2 19.7 6.5 10.6 3.6 11.2 11.7 11.6 5.6 14.5 7.7 8.7 4.9 HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94501434-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 182.0;Spermatogonia: 173.9" "Cancer enhanced" "Detected in all" "testis cancer: 16.1" "Region enhanced" "Detected in many" "cerebellum: 5.5" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 36.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: AB_627895, HPA063242: AB_2684968" "unprognostic (1.94e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.85e-2)" "unprognostic (3.38e-2)" "unprognostic (8.65e-2)" "unprognostic (4.85e-3)" "unprognostic (1.76e-5)" "unprognostic (7.59e-3)" "unprognostic (7.03e-3)" "unprognostic (6.49e-2)" "unprognostic (2.05e-2)" "unprognostic (9.45e-5)" "unprognostic (9.93e-13)" "unprognostic (2.25e-2)" "unprognostic (1.72e-1)" "unprognostic (6.24e-2)" "unprognostic (3.03e-2)" 1.1 1.2 0.8 6.4 0.3 16.3 3.0 5.5 1.2 3.2 1.3 4.3 2.9 2.9 1.4 5.9 1.7 2.0 0.7 0.4 1.3 2.5 1.8 1.7 12.4 0.8 0.8 2.6 1.2 1.4 3.0 4.1 1.0 2.1 5.1 1.1 1.9 1.0 0.3 5.3 3.9 2.2 0.9 4.3 3.7 12.8 0.9 15.9 1.1 0.2 12.6 3.6 3.2 1.5 57.7 55.4 70.6 90.1 2.9 6.4 37.4 42.9 27.8 34.4 54.6 70.3 45.5 70.0 16.7 15.5 29.1 56.3 40.9 34.9 50.7 68.5 45.5 37.3 56.3 58.0 1.7 71.2 31.6 3.6 2.0 42.1 20.0 9.4 24.0 46.0 20.7 43.5 43.1 54.9 75.2 35.6 73.4 42.3 24.1 70.3 62.1 16.3 24.2 72.2 28.4 22.8 50.3 14.5 7.8 59.0 60.9 23.1 17.2 38.4 19.4 35.4 52.4 22.3 47.6 74.5 19.0 42.8 17.9 0.3 0.7 0.0 7.0 1.5 2.4 18.8 11.4 9.4 2.3 23.2 5.2 7.7 1.0 10.2 1.0 36.8 19.7 2.3 0.8 0.3 5.5 1.2 0.4 1.3 0.8 0.8 1.0 0.9 0.9 1.5 4.7 9.6 3.9 0.0 19.7 21.5 11.5 12.6 13.1 16.4 10.0 15.0 1.0 12.8 12.6 22.0 0.0 46.3 13.2 26.2 3.9 9.0 2.0 9.3 16.4 8.1 10.8 50.5 3.3 6.2 43.4 13.0 17.9 16.3 5.7 60.6 5.7 3.6 15.1 6.7 5.4 17.8 8.2 2.2 10.3 5.3 9.0 7.3 1.8 9.4 5.7 4.3 1.0 4.5 6.6 4.7 1.8 5.7 37.5 3.7 1.7 1.6 6.3 11.4 19.7 10.5 16.4 182.0 173.9 22.9 9.9 11.1 15.7 16.5 30.9 11.7 HELZ "DHRC, HUMORF5, KIAA0054" ENSG00000198265 "Helicase with zinc finger" P42694 17 67070444-67245989 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028276 Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Actin filaments" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Nucleoli rim" "Plasma membrane, Actin filaments" "HPA028276: AB_10601814" "unprognostic (3.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.56e-3)" "unprognostic (1.29e-1)" "unprognostic (4.83e-2)" "unprognostic (4.71e-2)" "unprognostic (5.85e-2)" "unprognostic (5.31e-2)" "unprognostic (3.60e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-3)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" 6.3 6.6 3.8 8.5 4.9 12.5 6.6 12.0 5.7 7.6 8.4 5.8 4.8 7.4 6.1 4.7 6.1 7.1 6.1 3.6 6.9 6.9 10.9 6.8 9.8 4.1 5.2 12.3 7.8 12.0 6.1 11.2 4.0 6.1 6.6 14.3 6.2 6.2 9.1 4.4 5.9 7.5 3.3 9.1 6.5 10.8 5.5 15.4 8.7 14.0 8.9 6.6 5.0 3.3 10.3 10.0 12.3 12.3 14.8 8.4 18.7 9.0 8.8 11.8 12.4 14.7 7.9 21.2 7.2 12.0 7.4 10.5 23.3 11.3 18.4 8.2 7.3 27.2 10.7 12.5 7.1 22.3 15.6 9.8 10.5 11.4 14.1 8.8 18.1 15.6 19.1 12.9 9.8 13.0 29.0 7.6 7.4 9.2 9.7 19.3 21.6 9.2 9.1 14.3 12.0 11.0 14.3 11.5 15.2 16.9 13.7 13.7 16.1 14.5 16.6 8.0 8.1 10.7 13.4 15.5 7.2 13.7 15.5 2.3 3.3 2.8 5.1 2.8 6.3 1.7 3.1 3.2 2.8 2.8 1.9 2.6 2.3 2.6 1.9 2.2 3.0 2.3 3.8 4.9 12.0 5.7 3.6 6.9 4.1 5.2 4.0 3.3 5.5 3.3 42.9 19.2 37.1 89.1 44.3 32.1 24.6 30.2 29.6 50.8 32.8 23.6 31.1 24.3 30.2 27.6 93.8 32.9 95.8 29.4 7.9 19.1 5.2 49.4 55.8 32.3 38.3 48.8 93.1 14.2 42.8 30.9 38.7 118.5 33.7 51.9 61.8 52.1 31.9 67.3 112.1 30.2 16.2 79.4 28.8 10.5 38.8 55.4 14.2 107.7 62.0 24.0 104.0 134.2 72.6 19.2 23.1 42.9 67.1 29.3 27.7 14.6 26.1 54.9 13.1 45.9 34.0 36.0 26.0 33.6 20.2 18.3 71.0 32.6 26.3 45.8 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HES4 bHLHb42 ENSG00000188290 "Hes family bHLH transcription factor 4" Q9HCC6 1 998962-1000172 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 345.1;Paneth cells: 397.4;Prostatic glandular cells: 286.6;Smooth muscle cells: 385.7;Urothelial cells: 494.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "eosinophil: 12.4" "Lineage enriched" "Detected in many" 10 "granulocytes: 12.4" "Cell line enriched" "Detected in many" 7 "HEK 293: 198.1" "Low region specificity" "Detected in all" HPA062465 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA062465: AB_2684771" "unprognostic (6.23e-2)" "unprognostic (3.77e-2)" "unprognostic (7.07e-2)" "prognostic favorable (3.85e-4)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.99e-4)" "unprognostic (6.25e-3)" "unprognostic (2.34e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-1)" "unprognostic (7.76e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (3.97e-1)" "unprognostic (3.87e-2)" "unprognostic (1.86e-1)" "unprognostic (5.08e-3)" 10.5 1.9 12.9 0.7 15.3 0.5 9.1 8.1 34.3 9.2 0.9 11.0 1.2 10.5 0.4 7.5 10.3 0.1 22.6 6.8 17.9 13.6 3.0 10.8 0.2 22.3 15.8 3.9 5.6 0.9 8.4 1.5 17.0 11.4 0.3 0.8 7.7 2.2 4.0 8.4 3.9 1.2 6.0 4.4 5.6 2.6 24.0 1.4 6.0 0.9 0.3 10.0 8.4 4.0 14.3 1.6 1.5 0.2 0.2 0.1 17.6 8.6 1.0 5.2 5.4 2.3 4.5 0.0 20.0 0.7 2.3 25.3 2.1 0.3 0.2 0.1 198.1 0.1 2.4 2.9 1.7 0.0 1.7 0.1 2.0 0.3 0.4 0.7 0.6 2.5 4.1 0.3 0.0 7.6 11.7 0.6 0.2 3.1 19.2 0.2 1.9 4.4 2.0 0.0 1.1 4.6 5.8 14.3 29.1 0.7 10.5 0.0 1.1 1.6 0.6 0.0 4.0 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.0 12.4 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 12.9 15.3 8.1 34.3 6.8 17.9 22.3 15.8 17.0 6.0 24.0 4.0 90.1 0.0 0.0 18.6 15.3 52.1 345.1 1.7 6.8 8.9 158.9 149.4 13.3 20.0 4.0 58.8 0.0 1.5 22.3 88.3 31.3 44.1 1.0 74.7 30.0 63.4 10.7 2.7 12.9 2.9 43.9 65.5 11.2 153.3 53.5 3.1 37.5 0.8 4.8 0.0 25.9 25.4 4.1 10.0 120.5 1.5 7.5 70.8 115.6 11.2 5.2 129.7 12.3 8.5 1.7 10.7 397.4 15.4 2.3 286.6 1.5 0.8 1.1 11.3 164.3 157.8 385.7 3.2 29.6 43.0 82.7 3.4 27.4 2.0 56.9 494.9 HES5 bHLHb38 ENSG00000197921 "Hes family bHLH transcription factor 5" Q5TA89 1 2528745-2530263 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 18.7;skin 1: 4.8" "Cell type enhanced" "Detected in some" "Adipocytes: 24.8;Astrocytes: 53.5;Muller glia cells: 113.4;Oligodendrocyte precursor cells: 15.6" "Cancer enriched" "Detected in some" 5 "glioma: 3.8" "Group enriched" "Detected in many" 4 "amygdala: 10.3;basal ganglia: 14.2;cerebral cortex: 5.1;hypothalamus: 12.4;thalamus: 18.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA065458, HPA076164" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" No NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear speckles, Cytosol" "HPA065458: AB_2685492, HPA076164: AB_2732303" "unprognostic (2.04e-3)" "unprognostic (2.83e-2)" "unprognostic (4.26e-2)" "unprognostic (2.75e-3)" "unprognostic (5.26e-3)" "unprognostic (1.60e-4)" "unprognostic (1.76e-4)" "unprognostic (1.60e-1)" "unprognostic (5.30e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-1)" "unprognostic (4.67e-1)" "unprognostic (9.95e-4)" "unprognostic (1.14e-3)" "unprognostic (1.45e-1)" "unprognostic (3.89e-2)" "unprognostic (1.72e-1)" 0.5 0.0 10.3 0.0 14.2 0.0 0.3 0.7 5.1 0.4 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 2.5 2.8 12.4 0.1 0.3 0.3 0.0 1.1 0.9 0.1 0.0 0.0 2.5 0.0 1.0 0.4 0.0 0.0 0.1 0.0 0.1 4.8 0.2 0.0 0.4 0.2 0.1 0.9 18.7 0.0 0.5 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 14.2 0.7 5.1 2.8 12.4 1.1 0.9 1.0 0.4 18.7 0.0 24.8 0.0 0.0 53.5 0.2 0.1 0.3 0.2 1.8 2.9 1.1 2.8 1.4 0.0 0.3 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 5.4 0.8 5.1 0.0 0.0 0.7 0.0 0.0 0.3 0.0 8.9 0.0 0.1 0.0 0.0 0.0 3.3 0.8 4.9 0.0 0.0 0.8 0.0 0.0 0.3 0.0 1.9 0.0 113.4 0.0 15.6 0.3 0.0 2.9 0.0 0.0 0.5 0.1 0.0 0.0 7.7 0.0 1.0 6.2 0.0 0.4 6.2 1.4 0.0 0.5 0.0 3.0 0.2 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HGH1 "Brp16, C8orf30A, C8orf30B, FAM203A, FAM203B, FLJ40907, LOC51236" ENSG00000235173 "HGH1 homolog" Q9BTY7 8 144137774-144140851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 26.4;PC-3: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042470 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" Nucleoplasm "HPA042470: AB_2678013" "unprognostic (2.13e-2)" "prognostic unfavorable (3.12e-4)" "unprognostic (9.72e-2)" "unprognostic (2.63e-1)" "unprognostic (9.82e-2)" "unprognostic (2.17e-1)" "unprognostic (7.89e-3)" "unprognostic (1.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.30e-2)" "unprognostic (4.39e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (4.62e-3)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" 2.3 3.2 1.8 1.0 1.3 0.6 1.5 1.4 1.8 2.0 1.2 1.9 0.6 2.3 0.1 3.1 1.7 0.5 2.1 1.7 1.1 1.9 3.2 1.3 0.6 2.1 1.2 1.7 3.1 0.8 1.4 0.4 1.4 1.9 0.5 0.1 1.8 0.8 2.7 2.2 1.6 0.7 1.3 2.2 2.9 2.4 1.5 0.6 2.0 1.2 0.6 2.6 1.9 1.6 8.3 2.7 1.9 3.5 2.7 1.7 4.9 13.8 1.1 2.9 1.9 3.6 2.1 23.9 18.7 2.6 1.1 8.6 3.8 1.9 0.9 11.7 14.5 9.1 2.4 1.8 2.6 5.1 5.9 1.2 5.9 3.2 2.0 1.0 1.3 4.9 26.4 0.9 1.8 6.9 17.5 4.7 5.4 3.1 46.6 21.8 1.6 3.7 1.7 1.9 4.1 4.4 6.4 3.4 5.1 0.6 2.9 1.8 4.9 1.7 14.2 5.1 16.5 13.9 9.7 6.1 1.7 8.5 2.8 0.0 0.1 0.0 0.3 0.2 0.2 0.1 0.4 0.7 0.2 0.8 0.4 0.3 0.0 0.6 0.2 0.1 0.1 0.1 1.8 1.3 1.4 1.8 1.7 1.1 2.1 1.2 1.4 1.3 1.5 1.6 5.2 0.0 2.4 2.6 5.8 0.0 2.6 0.0 5.2 4.2 6.7 5.7 2.2 2.8 0.6 5.5 0.0 11.1 7.2 1.3 11.7 3.5 11.2 2.8 7.0 3.1 4.9 5.9 1.2 1.8 13.4 4.3 7.1 4.0 0.0 7.9 1.4 9.9 12.2 6.7 1.2 4.0 0.0 4.8 0.0 22.1 7.5 5.6 0.0 1.0 3.5 8.3 14.4 0.0 1.0 2.9 5.6 3.4 4.9 3.2 5.4 10.2 1.5 3.7 6.6 2.6 3.8 15.1 14.8 6.9 0.0 3.1 5.9 11.0 6.5 1.6 HGS "Hrs, Vps27, ZFYVE8" ENSG00000185359 "Hepatocyte growth factor-regulated tyrosine kinase substrate" O14964 17 81683326-81703138 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004872, HPA007728" Uncertain Enhanced Endosomes,Lysosomes,Cytosol NA NA 45000 "Cluster 18: Basophils - Vesicular transport" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Endosomes, Lysosomes" Cytosol "HPA004872: AB_1079053, HPA007728: AB_1850681" "unprognostic (6.52e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.29e-1)" "unprognostic (1.31e-2)" "unprognostic (4.91e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.61e-5)" "unprognostic (5.54e-3)" "unprognostic (1.09e-1)" "unprognostic (9.27e-2)" "unprognostic (5.30e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (4.31e-7)" "unprognostic (3.69e-1)" "unprognostic (2.27e-1)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" 73.3 95.6 101.5 24.8 102.2 54.5 69.7 98.9 127.1 81.4 98.2 75.7 29.3 66.7 32.7 118.8 70.2 27.0 82.1 103.3 99.3 100.8 85.7 80.1 30.6 105.9 103.2 74.4 85.1 28.1 81.7 24.8 104.3 86.3 25.3 15.7 72.4 29.6 93.7 95.2 81.2 28.5 98.1 100.6 84.6 105.9 102.7 35.3 68.5 18.5 24.8 81.1 83.9 104.1 104.2 93.1 47.8 66.6 56.0 59.8 57.3 65.5 86.6 99.6 76.8 72.6 65.0 23.4 47.2 106.4 88.6 63.2 43.7 100.6 45.8 19.7 76.0 58.8 98.8 117.5 92.8 47.1 55.4 78.1 100.9 93.9 121.9 82.7 120.9 44.5 54.8 30.4 92.1 77.9 58.1 71.4 43.8 75.9 88.9 51.3 48.6 41.0 94.5 87.7 54.9 86.1 54.6 114.9 78.3 48.3 82.3 98.6 87.3 119.5 82.4 69.6 123.3 41.6 17.6 21.8 96.9 53.3 89.4 48.8 28.7 38.9 24.5 32.3 16.6 16.4 18.5 19.4 23.5 15.8 14.1 16.0 44.7 27.1 33.6 19.3 22.3 35.9 101.5 102.2 98.9 127.1 103.3 99.3 105.9 103.2 104.3 98.1 102.7 104.1 20.8 25.6 28.7 17.6 22.0 27.9 23.8 27.7 29.6 30.6 27.0 25.9 3.1 17.2 27.6 22.0 35.5 34.0 27.4 60.9 1.9 43.3 72.3 45.6 28.7 26.3 11.4 23.4 14.2 42.6 36.5 21.8 68.8 66.1 23.4 26.3 16.1 20.7 29.5 23.5 12.6 32.4 22.4 22.9 26.6 137.8 28.9 30.3 23.2 15.9 28.1 20.6 25.7 6.6 16.1 68.2 42.7 23.0 27.6 53.9 41.1 14.6 32.3 35.5 13.1 17.8 24.0 36.9 32.5 37.0 30.3 50.2 23.5 22.1 36.2 50.8 HIF3A "bHLHe17, IPAS, MOP7, PASD7" ENSG00000124440 "Hypoxia inducible factor 3 subunit alpha" Q9Y2N7 19 46297042-46343433 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Apoptosis, Stress response, Transcription, Transcription regulation" "Developmental protein, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 83.5;Astrocytes: 257.9;Endothelial cells: 60.4;Leydig cells: 136.4;Muller glia cells: 79.9;Oligodendrocyte precursor cells: 69.9;Peritubular cells: 103.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.3;HHSteC: 19.1;HSkMC: 16.8;TIME: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041141 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041141: AB_10803997" "unprognostic (9.20e-2)" "unprognostic (2.99e-1)" "unprognostic (5.48e-2)" "prognostic unfavorable (6.90e-9)" "unprognostic (4.12e-2)" "unprognostic (2.35e-2)" "unprognostic (3.57e-3)" "unprognostic (1.30e-1)" "unprognostic (3.32e-2)" "unprognostic (1.38e-2)" "unprognostic (3.76e-2)" "unprognostic (7.07e-2)" "unprognostic (3.41e-4)" "unprognostic (1.55e-2)" "unprognostic (1.61e-1)" "unprognostic (4.45e-4)" "unprognostic (5.98e-2)" 34.2 8.8 24.1 1.1 24.7 0.7 24.2 17.5 25.9 32.5 9.4 55.4 1.1 31.1 4.1 10.8 35.8 2.6 55.9 19.5 17.4 7.3 2.7 32.8 1.2 22.2 22.3 34.2 6.5 0.5 22.6 27.4 18.6 22.3 2.0 10.0 7.5 7.1 10.7 10.8 24.8 3.0 16.8 31.8 37.3 5.4 22.5 0.5 13.0 9.7 0.4 55.0 25.1 17.3 0.0 0.0 1.5 0.2 4.3 9.3 0.4 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 19.1 0.1 0.5 16.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 2.3 0.0 0.1 16.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.7 0.1 0.4 0.7 0.1 0.0 24.1 24.7 17.5 25.9 19.5 17.4 22.2 22.3 18.6 16.8 22.5 17.3 83.5 3.2 1.8 257.9 0.5 1.1 2.2 0.3 0.6 1.5 1.4 0.9 45.7 17.2 0.7 0.0 0.0 0.2 0.3 0.2 1.9 0.0 1.9 2.4 7.0 60.4 1.2 8.0 0.7 0.0 0.4 13.6 1.1 2.3 0.0 3.1 51.0 0.9 0.6 0.0 3.5 1.2 0.0 1.3 2.1 7.4 136.4 0.7 3.6 33.7 0.0 79.9 0.0 69.9 1.2 0.1 8.0 103.4 0.0 1.6 0.5 0.1 0.0 2.5 6.6 5.5 8.4 1.6 3.6 0.2 2.3 0.5 0.4 0.1 2.1 0.7 HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.6;choroid plexus: 65.0;placenta: 105.2" "Group enriched" "Detected in some" 5 "Sertoli cells: 762.6;Smooth muscle cells: 209.3" "Cancer enhanced" "Detected in all" "glioma: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (6.85e-2)" "unprognostic (9.41e-2)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (8.46e-2)" "unprognostic (2.37e-2)" "unprognostic (4.98e-3)" "unprognostic (3.61e-1)" "unprognostic (1.18e-2)" "unprognostic (3.98e-1)" "unprognostic (6.19e-2)" "unprognostic (3.56e-1)" "unprognostic (1.61e-3)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.52e-2)" 11.7 0.5 71.0 0.7 71.0 0.5 8.8 70.3 114.6 8.3 65.0 3.7 2.1 9.9 11.6 5.0 5.3 11.3 46.4 68.8 71.4 11.5 0.6 38.6 2.6 71.4 70.9 2.9 3.1 8.0 1.4 105.2 72.4 9.5 1.1 2.3 1.4 6.4 14.5 2.0 4.3 11.3 68.9 0.1 3.7 1.5 73.0 1.8 5.0 30.8 1.4 4.3 4.4 69.1 0.2 0.6 0.0 0.7 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.3 0.2 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.1 0.8 0.5 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.7 0.5 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.8 0.4 1.0 0.0 0.5 0.7 0.3 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.6 0.2 0.4 0.5 0.4 1.2 0.6 0.5 1.1 0.7 1.7 0.6 0.2 1.2 1.0 0.4 0.2 0.7 0.9 1.2 0.3 0.9 0.7 0.0 0.7 0.1 0.3 0.8 0.5 71.0 71.0 70.3 114.6 68.8 71.4 71.4 70.9 72.4 68.9 73.0 69.1 88.9 0.0 0.5 0.0 0.3 3.4 0.6 0.3 0.0 0.5 1.2 2.8 11.0 0.0 1.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.7 70.2 0.0 0.0 0.7 0.0 0.2 4.4 0.0 0.3 0.0 0.0 0.7 0.1 0.8 1.7 0.6 0.0 0.0 0.0 3.9 0.6 0.3 1.6 0.0 2.8 0.0 1.0 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 762.6 9.5 209.3 0.0 0.3 0.7 2.4 0.3 0.8 32.3 0.0 0.7 HIKESHI "C11orf73, HSPC138, HSPC179, OPI10" ENSG00000149196 "Heat shock protein nuclear import factor hikeshi" Q53FT3 11 86302211-86345943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Extravillous trophoblasts: 146.2;Hofbauer cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012708, HPA035063, HPA035064" Approved Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA012708: , HPA035063: AB_10601143, HPA035064: AB_2674441" "unprognostic (1.10e-3)" "unprognostic (5.09e-2)" "unprognostic (1.92e-1)" "unprognostic (2.40e-2)" "unprognostic (1.50e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (8.81e-4)" "unprognostic (9.92e-2)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (8.24e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (4.01e-12)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.33e-3)" "unprognostic (1.71e-1)" 34.7 27.0 46.1 17.8 46.7 19.0 31.4 47.8 71.5 33.9 44.5 40.8 10.4 32.3 24.7 33.4 31.0 15.0 57.1 46.1 47.2 17.0 24.7 23.9 26.0 46.6 46.0 37.5 22.8 22.9 31.5 28.3 47.1 24.5 19.1 32.5 19.8 28.6 59.9 29.5 20.8 31.1 49.1 28.5 23.5 19.0 47.1 32.9 17.7 57.8 30.8 32.8 31.8 50.9 28.6 30.5 72.7 40.5 59.9 74.2 38.2 43.2 52.0 44.2 52.6 90.8 77.8 29.0 96.9 57.4 83.9 59.9 54.2 95.1 47.0 62.0 47.6 47.0 47.5 68.2 80.8 58.0 36.8 52.7 94.9 52.8 62.5 56.9 85.9 54.7 51.1 64.6 91.5 78.0 69.6 136.7 59.5 186.3 20.1 53.0 35.7 65.4 77.2 53.2 44.8 38.7 53.8 39.8 31.1 72.7 64.1 38.5 44.2 52.1 36.4 105.8 32.7 27.7 68.3 57.6 26.6 54.4 52.6 47.8 53.4 44.4 48.6 52.5 54.3 61.8 59.1 53.6 68.9 52.9 51.1 52.3 11.2 57.9 53.9 53.7 84.5 43.2 46.1 46.7 47.8 71.5 46.1 47.2 46.6 46.0 47.1 49.1 47.1 50.9 59.9 38.5 32.1 0.0 16.1 0.0 0.0 0.0 0.0 0.0 53.4 81.3 0.0 0.0 14.9 27.6 0.0 129.6 28.7 0.0 41.1 76.1 0.0 41.4 60.4 28.7 0.0 0.0 0.0 66.3 146.2 30.2 0.0 36.8 22.7 52.1 0.0 0.0 94.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 50.1 0.0 0.0 0.0 0.0 49.8 0.0 0.0 4.1 0.0 0.0 43.2 27.7 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 77.6 18.1 59.3 0.0 0.0 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HINT3 "FLJ33126, HINT4" ENSG00000111911 "Histidine triad nucleotide binding protein 3" Q9NQE9 6 125956770-125980244 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.8" "Cell type enhanced" "Detected in all" "Early spermatids: 352.2;Spermatocytes: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027914 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitochondria" Cytosol "HPA027914: AB_10602424" "prognostic unfavorable (4.99e-4)" "unprognostic (4.75e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.74e-1)" "unprognostic (4.88e-3)" "unprognostic (3.82e-1)" "unprognostic (1.27e-1)" "unprognostic (2.18e-2)" "unprognostic (1.05e-1)" "prognostic favorable (1.05e-6)" "unprognostic (4.09e-2)" "unprognostic (4.76e-2)" "unprognostic (9.56e-2)" "unprognostic (1.64e-1)" 18.1 23.4 31.2 12.6 33.9 12.3 23.0 31.0 43.3 18.3 22.8 19.6 15.7 16.6 17.8 22.3 16.4 16.2 28.4 29.4 31.4 22.2 28.3 21.0 11.3 33.9 32.1 14.7 19.3 30.6 14.4 14.5 33.8 29.7 17.6 15.3 25.5 22.4 112.8 17.5 16.0 17.3 36.6 10.5 24.8 12.3 32.5 13.6 23.5 84.6 11.4 18.4 10.8 38.0 13.2 10.3 14.1 29.5 5.5 14.8 17.5 14.1 20.2 10.6 11.0 25.6 7.2 28.4 25.5 9.4 23.7 19.5 18.2 11.9 12.3 27.4 23.5 12.0 15.1 21.6 25.4 19.2 19.6 11.8 25.9 10.7 27.0 27.3 16.1 21.0 38.3 18.7 10.6 20.1 15.5 13.7 4.8 27.1 9.9 12.8 9.7 9.7 21.8 24.0 28.2 17.4 12.9 18.0 67.8 10.2 18.4 28.9 11.4 7.2 10.1 34.8 20.3 27.1 33.3 18.2 20.4 18.1 9.5 12.5 9.3 8.9 4.4 5.9 4.6 7.0 5.9 4.8 7.7 6.3 6.0 5.3 11.2 5.9 8.6 4.3 6.3 5.3 31.2 33.9 31.0 43.3 29.4 31.4 33.9 32.1 33.8 36.6 32.5 38.0 11.7 80.1 61.2 11.8 16.7 18.1 10.2 22.1 24.5 21.8 26.5 18.4 38.7 10.0 29.8 16.5 8.4 19.2 13.4 17.2 33.2 29.3 352.2 23.6 11.5 12.3 16.3 6.9 27.0 20.2 6.4 13.7 19.4 25.8 9.5 15.2 10.4 17.5 27.2 6.7 29.8 25.1 20.3 15.3 14.6 78.3 9.9 19.3 21.4 5.6 17.3 43.4 11.3 21.6 40.0 21.4 28.7 17.3 8.1 20.9 15.3 28.0 25.7 25.4 6.6 18.3 15.1 110.7 40.2 21.5 17.3 26.4 11.3 14.6 18.5 19.9 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929324-113977869 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 142.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 176.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" Centrosome "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" 19.8 20.0 24.7 20.2 23.5 142.0 16.8 44.5 20.9 24.4 42.4 19.0 12.7 18.1 17.2 23.1 35.0 22.2 18.0 20.6 32.5 18.2 17.8 23.4 20.9 37.2 39.4 22.8 21.8 21.3 20.5 17.7 29.8 15.4 18.9 56.5 15.2 17.7 25.7 23.4 16.8 18.2 36.9 20.7 17.8 47.1 27.5 57.4 29.8 27.1 20.6 19.7 18.8 25.6 23.4 18.8 25.4 19.5 29.2 15.2 17.1 15.8 19.0 22.2 20.9 21.8 8.8 31.4 21.2 25.3 8.2 15.5 33.1 18.6 31.7 23.0 16.7 45.8 23.7 23.0 24.3 36.7 54.2 16.5 26.5 28.3 28.7 20.8 33.2 54.2 31.8 32.8 32.1 176.4 48.8 21.0 26.2 17.1 15.8 29.1 74.4 10.9 19.8 19.9 11.2 15.0 28.9 30.6 20.5 27.9 17.7 52.3 32.6 21.5 29.0 35.3 24.3 20.1 17.2 26.7 23.7 29.3 50.3 2.1 2.5 5.0 3.0 2.1 3.0 0.9 2.7 2.8 1.7 1.1 2.6 3.3 5.8 2.7 1.6 3.7 2.0 1.5 24.7 23.5 44.5 20.9 20.6 32.5 37.2 39.4 29.8 36.9 27.5 25.6 30.1 54.5 37.2 14.4 26.0 61.4 16.2 16.7 15.4 57.7 29.8 20.2 34.6 22.8 24.5 27.6 70.9 10.7 125.8 38.9 5.9 14.6 95.2 147.9 33.4 28.9 37.2 64.4 27.4 21.0 10.3 24.3 20.9 47.0 46.9 26.3 21.8 37.4 22.2 74.0 33.9 25.4 12.2 49.5 77.7 101.4 22.1 50.2 21.4 31.9 43.1 30.6 36.0 21.1 26.5 18.8 22.4 37.2 43.5 33.7 17.8 16.4 116.4 64.8 26.3 36.5 44.3 49.7 31.5 25.6 80.6 14.2 69.7 21.9 28.3 32.7 HIVEP1 "CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A" ENSG00000095951 "HIVEP zinc finger 1" P15822 6 12008762-12164999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050724, HPA067457" Approved Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA050724: AB_2616457, HPA067457: " "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" "unprognostic (1.15e-1)" "unprognostic (6.03e-2)" "unprognostic (1.75e-2)" "unprognostic (5.65e-3)" "unprognostic (4.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.85e-1)" "unprognostic (5.69e-2)" "unprognostic (1.98e-1)" "unprognostic (4.40e-2)" "unprognostic (3.01e-2)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (2.38e-1)" 7.2 2.3 0.8 8.0 3.0 16.7 5.5 0.7 3.0 7.4 6.5 6.4 5.0 5.9 4.5 7.4 6.1 7.3 3.8 2.2 0.8 4.5 11.7 6.3 8.0 1.3 2.8 6.5 6.7 10.5 3.3 4.9 0.5 6.9 6.6 5.8 4.8 5.8 2.8 5.7 5.2 6.2 0.0 6.0 4.9 4.8 1.2 9.1 4.9 6.2 8.3 9.3 3.3 1.6 8.1 5.9 7.5 4.2 5.8 7.3 7.2 6.4 5.5 5.2 5.7 3.8 4.2 6.7 13.6 7.8 12.4 7.6 7.4 9.2 7.1 14.6 4.3 3.1 5.6 3.7 4.7 3.7 2.5 5.1 9.0 10.6 16.3 11.0 15.5 4.6 32.9 7.5 11.5 6.0 5.9 3.3 6.4 2.8 2.7 3.2 9.8 10.7 3.1 8.7 7.1 5.2 15.9 12.8 4.3 16.6 7.6 4.7 25.2 13.0 5.8 12.3 7.4 30.0 27.3 12.0 4.0 4.8 5.5 2.4 1.8 2.1 1.2 2.0 0.9 3.1 2.0 0.8 1.2 4.8 3.4 2.1 11.7 3.3 5.2 9.0 4.4 0.7 0.8 3.0 0.7 3.0 2.2 0.8 1.3 2.8 0.5 0.0 1.2 1.6 40.2 28.9 16.9 74.7 35.6 32.2 25.4 7.4 30.7 20.4 12.3 10.9 10.4 17.2 17.6 7.3 12.5 3.4 18.7 17.5 3.9 5.6 2.5 37.7 16.4 20.3 10.8 6.5 94.6 7.2 1.8 25.2 22.4 51.0 7.6 7.0 6.4 12.3 5.9 21.9 68.3 14.4 4.1 9.6 47.9 1.8 3.7 23.1 19.6 44.0 29.6 13.1 5.2 59.3 25.0 11.5 10.3 4.5 33.6 25.2 6.7 2.5 16.7 9.7 0.0 21.0 17.1 3.9 3.5 18.7 33.4 5.2 18.8 6.6 8.6 23.7 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 HMBOX1 "FLJ21616, HNF1LA, HOT1, PBHNF" ENSG00000147421 "Homeobox containing 1" Q6NT76 8 28890395-29064764 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.0" "Cell type enhanced" "Detected in all" "Astrocytes: 125.7;Oligodendrocyte precursor cells: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055855, HPA058586, CAB070418" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies, Cytosol" "CAB070418: AB_11154826, HPA055855: AB_2682945, HPA058586: AB_2683764" "unprognostic (2.68e-3)" "unprognostic (2.30e-3)" "unprognostic (4.52e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.20e-1)" "unprognostic (2.75e-3)" "unprognostic (1.49e-1)" "unprognostic (4.25e-2)" "unprognostic (1.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (3.84e-2)" "unprognostic (2.81e-1)" "unprognostic (1.02e-1)" "unprognostic (1.47e-1)" 4.6 6.7 7.6 5.1 11.9 10.8 4.2 10.6 5.7 3.7 1.7 3.8 3.1 4.4 3.0 3.2 3.7 4.2 4.5 5.3 17.9 4.3 4.2 4.6 5.3 15.0 20.0 6.1 3.3 5.0 1.8 6.8 15.6 2.9 3.9 6.2 3.1 2.5 2.8 4.4 4.3 5.2 10.4 5.7 4.3 7.6 11.6 4.9 6.2 3.7 5.9 3.8 2.4 12.9 6.2 6.8 7.1 8.2 6.5 6.7 6.0 2.6 3.5 4.0 4.3 3.1 3.9 15.1 6.3 4.5 6.0 5.3 14.4 5.3 5.6 5.5 2.4 15.6 13.8 4.2 5.3 5.4 10.2 3.3 7.5 5.3 10.1 4.9 9.1 9.0 22.7 14.4 5.7 3.8 9.9 2.7 5.0 6.6 1.6 8.1 7.1 3.4 2.8 11.5 3.0 9.2 5.1 3.9 5.4 5.9 3.9 4.8 13.0 3.6 16.8 3.9 3.8 4.4 4.8 5.9 4.6 6.5 5.4 3.2 2.4 1.1 1.9 2.6 2.7 3.4 1.9 1.8 2.5 2.6 2.4 2.4 1.4 1.2 4.7 1.9 0.8 1.4 7.6 11.9 10.6 5.7 5.3 17.9 15.0 20.0 15.6 10.4 11.6 12.9 25.5 16.0 18.1 125.7 30.3 16.7 15.8 18.1 15.9 24.4 15.3 10.5 23.6 20.0 14.0 29.5 39.6 12.9 18.7 16.2 15.6 8.3 93.0 15.0 21.2 34.2 17.4 19.6 90.1 14.4 14.1 19.2 11.2 29.4 17.1 36.7 68.6 13.7 10.3 30.3 109.8 12.9 22.4 19.8 36.4 31.5 35.8 20.1 16.0 91.8 21.4 28.3 26.8 118.1 111.8 14.1 11.3 31.6 14.4 21.0 20.4 8.8 14.3 31.6 19.7 34.6 17.3 43.6 15.2 10.1 19.7 19.2 22.8 19.5 14.7 22.6 HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.0;Early spermatids: 18.4;Glandular and luminal cells: 17.3;Granulosa cells: 29.7;Pancreatic endocrine cells: 19.9;Smooth muscle cells: 33.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 324.4;hTERT-RPE1: 232.6;SuSa: 216.1" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" 0.4 0.0 0.3 0.3 0.2 4.9 0.2 0.7 0.5 1.1 0.0 2.1 1.3 0.4 0.0 0.3 1.2 0.3 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.6 0.9 0.0 0.4 0.2 0.2 0.0 2.4 0.5 0.1 0.1 1.5 0.4 1.0 0.1 0.1 0.1 1.1 3.8 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.4 47.9 21.4 324.4 45.8 15.0 82.0 0.1 148.5 68.5 26.0 25.8 28.1 19.8 0.0 92.3 7.0 120.0 20.5 54.2 129.3 123.8 0.2 56.2 0.2 0.7 169.3 8.4 4.7 0.4 62.7 8.0 55.2 98.4 232.6 105.0 0.2 0.1 0.6 149.9 0.2 0.4 27.8 190.3 4.6 89.2 12.7 16.1 0.1 68.9 0.3 0.0 0.0 0.1 0.1 85.0 216.1 0.5 0.7 120.8 89.5 26.9 71.2 45.3 0.2 0.2 0.4 112.0 0.3 21.4 1.4 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.3 0.6 0.1 0.0 0.0 0.3 0.2 0.7 0.5 0.2 0.1 0.4 0.2 0.2 0.1 0.2 0.4 0.0 0.0 1.1 5.9 0.2 0.0 3.6 16.0 2.8 0.0 0.1 0.1 1.7 0.0 3.0 0.0 0.0 0.8 0.0 5.0 0.0 2.5 18.4 10.4 0.8 0.6 0.0 7.4 0.8 0.8 0.5 2.3 3.1 17.3 0.0 29.7 0.7 0.0 9.0 0.0 0.9 5.1 4.1 0.0 0.0 9.0 0.3 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.9 19.9 4.5 0.0 0.4 5.5 4.0 0.3 7.3 0.0 0.0 1.1 33.7 13.5 0.6 0.3 0.1 0.8 0.3 0.3 8.4 1.1 HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 390.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 511.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 797.7;GAMG: 523.5;HBEC3-KT: 467.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 470000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: AB_2675380, HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favorable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" 19.2 55.2 25.2 27.2 32.9 15.8 40.1 23.0 38.6 56.4 16.8 50.2 93.6 19.8 36.1 137.5 12.4 23.3 16.1 36.1 44.6 32.8 390.2 51.4 21.5 46.5 34.7 21.6 26.6 31.7 15.0 22.5 47.2 40.5 45.4 34.2 53.2 15.7 17.8 85.9 47.2 19.9 24.7 14.8 43.4 33.2 35.3 19.1 23.6 16.7 31.5 18.3 69.5 30.4 103.4 48.8 797.7 93.0 45.8 178.4 54.1 16.2 63.8 22.8 45.2 86.6 146.6 108.4 35.6 23.3 523.5 80.2 199.7 467.2 24.1 23.5 240.7 40.1 45.3 119.3 71.3 88.0 28.0 98.5 56.2 119.5 47.9 14.0 23.7 98.4 73.1 291.7 19.4 48.9 81.3 111.9 143.1 41.7 25.9 57.5 111.9 121.8 357.7 158.2 68.2 33.0 83.6 41.4 25.9 114.5 63.6 116.7 28.3 17.1 85.7 18.0 15.5 38.8 64.0 148.3 15.0 106.2 15.5 3.3 1.8 1.9 2.4 3.3 2.4 3.8 2.6 3.4 3.5 2.9 2.2 3.1 3.0 3.2 3.6 2.9 2.6 1.6 25.2 32.9 23.0 38.6 36.1 44.6 46.5 34.7 47.2 24.7 35.3 30.4 27.8 67.3 172.6 70.5 44.8 108.3 42.3 93.8 68.3 43.6 46.3 30.0 8.9 47.1 79.2 47.8 52.1 22.3 43.3 211.2 13.7 43.0 9.0 47.1 20.2 31.3 92.1 22.3 44.9 59.8 41.1 32.3 100.4 98.6 58.5 56.6 22.1 511.7 25.5 48.8 42.6 101.9 75.3 21.9 38.2 3.2 12.8 27.5 26.6 15.0 49.1 26.4 14.4 53.3 41.8 50.4 132.3 14.3 38.1 149.2 56.8 21.4 51.1 50.1 0.0 40.1 32.8 20.0 8.7 197.9 236.4 44.5 36.4 129.4 62.9 74.5 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Distal enterocytes: 51.0;Intestinal goblet cells: 32.3;Paneth cells: 54.3;Proximal enterocytes: 165.3;Undifferentiated cells: 36.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;CAPAN-2: 16.1;Karpas-707: 4.5;OE19: 10.0;PC-3: 4.8;THP-1: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" 0.2 0.0 0.2 2.5 0.5 0.0 1.0 0.2 0.3 2.3 0.1 20.6 100.5 0.4 1.2 0.3 1.0 12.1 0.0 0.3 0.3 17.4 12.9 0.2 0.1 0.4 0.5 0.0 5.6 0.0 0.0 0.1 0.3 0.6 19.6 0.0 0.4 0.4 0.0 0.0 114.6 0.9 0.4 0.1 8.1 3.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.1 4.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 16.1 0.0 2.2 0.0 1.8 0.0 2.0 0.0 0.0 0.0 1.8 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.3 10.0 4.8 0.0 0.0 0.3 2.7 0.1 0.3 1.6 0.3 0.1 0.0 0.2 0.2 5.5 0.0 0.3 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.3 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.0 0.0 1.1 39.8 0.5 0.0 0.6 0.4 2.2 0.0 1.3 0.5 0.2 17.2 1.5 3.7 0.0 0.0 0.0 51.0 5.9 3.2 3.1 3.6 0.2 0.0 16.3 0.0 0.5 4.3 0.0 0.1 8.2 3.2 0.0 0.0 0.0 10.7 0.0 0.0 0.6 32.3 2.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 0.6 5.6 54.3 0.0 0.0 1.6 165.3 18.5 8.1 0.0 0.0 0.1 0.4 4.8 0.0 0.4 0.0 0.0 0.2 0.0 36.9 2.9 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 299.3;Kupffer cells: 263.7;Proximal tubular cells: 268.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cell line enhanced" "Detected in many" "Hep G2: 227.2;HSkMC: 87.9;RT4: 117.1;SuSa: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" 70.4 18.2 13.0 41.7 13.3 12.6 62.3 13.1 18.8 57.3 19.2 53.9 29.3 62.8 27.1 17.5 34.5 68.7 21.7 15.6 19.1 109.7 245.9 49.0 35.1 16.0 15.3 91.0 29.0 40.2 9.5 46.8 18.1 37.0 56.4 6.1 30.5 44.3 5.9 17.4 29.1 33.1 16.1 37.5 29.1 10.3 14.5 8.2 14.6 11.9 16.4 49.7 24.5 22.2 0.7 0.9 5.6 14.6 61.9 64.6 0.4 3.9 6.2 0.4 2.3 29.7 15.7 0.9 50.2 17.0 0.8 1.1 11.9 0.0 0.1 0.7 4.9 0.2 44.5 227.2 28.0 0.3 0.6 87.9 0.1 21.5 0.0 4.7 15.9 0.1 0.5 0.7 47.4 3.7 0.0 0.5 28.1 39.3 5.6 0.5 1.5 0.2 67.9 117.1 0.1 0.8 22.1 28.4 0.1 107.9 1.0 53.2 4.8 4.8 11.8 6.2 16.3 0.4 0.3 0.7 20.9 27.8 3.3 1.3 110.9 0.7 0.5 89.8 0.3 1.8 0.2 0.2 68.3 0.5 0.3 0.4 3.9 0.5 52.2 1.5 0.7 32.6 13.0 13.3 13.1 18.8 15.6 19.1 16.0 15.3 18.1 16.1 14.5 22.2 15.5 28.9 44.1 9.4 5.0 35.6 81.5 64.6 30.7 0.7 78.1 65.4 2.2 133.0 88.9 60.7 0.0 54.9 2.6 59.4 123.3 122.1 1.5 28.3 50.6 9.4 16.4 16.8 16.8 48.0 81.6 54.2 20.9 115.3 0.0 17.4 19.2 165.7 299.3 0.0 13.8 67.8 24.4 263.7 97.2 4.2 131.4 127.4 56.9 31.9 122.0 25.5 4.1 45.8 14.3 71.0 108.6 105.3 0.2 39.8 31.9 268.3 38.4 0.8 78.9 55.2 55.7 0.5 0.9 33.2 25.9 37.6 4.0 43.9 83.5 126.1 HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Mitochondria, Cytosol" "HPA046084: AB_10960895" "unprognostic (2.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.63e-2)" "unprognostic (5.18e-1)" "unprognostic (2.10e-3)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.22e-4)" "unprognostic (1.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.80e-1)" "unprognostic (4.20e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-2)" 16.0 16.4 16.3 12.5 20.7 51.7 14.7 19.3 21.3 16.2 12.9 16.1 15.5 18.2 13.9 10.2 16.7 14.1 12.8 28.6 8.3 11.1 10.8 16.4 12.5 5.9 8.1 16.9 15.9 16.8 9.2 13.1 7.2 13.9 11.8 26.6 12.8 15.0 13.8 11.4 12.7 12.8 7.8 12.0 15.7 22.6 9.3 31.0 17.7 11.9 9.6 15.2 12.8 15.8 36.7 16.9 48.2 28.4 22.9 21.6 30.1 33.8 27.5 28.8 24.1 19.0 20.7 0.5 29.5 30.4 30.9 23.0 30.7 25.4 29.6 54.6 26.8 26.7 32.3 48.6 21.6 49.9 26.4 16.9 19.6 24.0 26.5 28.5 30.6 23.9 45.9 79.7 34.3 17.2 54.9 27.2 48.4 35.2 30.6 10.6 33.9 18.1 25.0 47.2 32.9 36.9 29.8 25.8 26.0 26.7 21.8 21.6 32.0 21.5 32.1 23.8 28.1 43.4 46.9 0.3 18.5 12.2 26.8 10.6 6.3 9.7 10.3 3.2 17.9 0.4 24.2 18.9 12.0 1.9 7.2 4.6 4.2 6.8 1.2 0.2 38.5 5.8 16.3 20.7 19.3 21.3 28.6 8.3 5.9 8.1 7.2 7.8 9.3 15.8 17.0 19.2 23.4 26.8 5.5 28.7 35.2 16.5 33.0 13.3 18.0 15.2 18.8 8.6 18.8 27.6 8.4 26.2 6.4 13.9 19.6 22.4 155.6 18.1 18.8 20.1 14.4 22.5 68.6 24.3 28.9 26.0 32.1 11.6 9.5 26.3 22.5 7.4 24.4 6.7 40.1 15.4 6.1 15.0 90.2 48.7 27.7 23.1 39.2 37.5 24.5 22.3 2.1 48.7 28.4 21.2 14.2 52.3 23.0 23.6 16.6 18.6 14.5 11.7 39.5 22.6 28.4 91.1 28.8 19.4 21.3 22.2 48.0 22.3 18.8 21.4 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: AB_1850913" "unprognostic (1.84e-2)" "unprognostic (1.61e-1)" "unprognostic (2.73e-1)" "unprognostic (8.61e-3)" "unprognostic (6.05e-2)" "unprognostic (1.77e-3)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" 9.8 6.2 3.1 7.4 8.7 11.1 8.9 11.9 8.9 8.2 1.5 7.5 7.5 8.3 8.2 10.6 7.0 14.4 4.6 4.0 11.1 6.6 7.3 8.0 6.6 7.6 4.9 6.1 7.6 7.2 4.1 8.6 7.3 12.4 7.7 8.8 9.6 7.1 10.6 8.1 8.9 6.7 4.4 6.6 9.5 11.4 4.9 6.4 21.7 8.2 7.4 9.3 6.0 15.5 11.2 10.9 26.2 14.2 19.0 16.7 10.1 14.0 11.6 11.5 10.7 14.5 12.8 13.9 13.9 18.8 10.9 6.4 22.1 9.5 18.5 9.5 6.4 26.3 9.2 10.2 10.6 2.8 14.9 13.7 6.6 15.4 13.2 15.9 16.7 9.7 14.7 15.9 14.0 2.7 21.7 5.2 9.5 8.8 3.3 12.6 27.3 3.5 8.6 16.5 6.7 10.6 15.9 6.7 7.4 11.4 12.2 9.4 30.2 17.1 13.2 20.9 9.0 15.6 18.6 18.1 14.5 9.9 25.8 9.4 2.0 2.0 1.2 2.0 0.4 0.9 1.1 0.9 2.4 0.9 0.6 0.8 2.2 1.2 1.9 1.4 0.8 1.1 3.1 8.7 11.9 8.9 4.0 11.1 7.6 4.9 7.3 4.4 4.9 15.5 75.3 93.0 60.6 90.1 43.2 68.3 36.2 28.7 43.3 40.1 29.4 22.4 48.2 44.3 43.6 25.8 33.3 43.6 40.6 26.1 27.4 47.1 120.3 60.0 84.0 65.2 65.4 34.5 102.1 32.8 25.9 65.8 33.1 93.8 53.8 37.9 60.3 36.4 38.0 75.7 107.6 26.9 20.3 79.4 96.4 36.3 44.7 82.8 55.2 78.7 118.6 36.3 37.0 119.1 157.8 59.7 27.6 53.8 43.6 43.5 37.3 21.4 35.2 32.2 65.7 63.4 74.6 28.0 21.5 39.8 74.7 113.7 40.9 42.6 16.2 71.1 HORMAD2 "CT46.2, MGC26710" ENSG00000176635 "HORMA domain containing 2" Q8N7B1 22 30080464-30177075 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.8" "Group enriched" "Detected in some" 7 "Early spermatids: 52.8;Spermatocytes: 133.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003074, HPA043880" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Centrosome, Cytosol" "HPA003074: AB_1850916, HPA043880: " "unprognostic (1.43e-1)" "unprognostic (6.77e-3)" "unprognostic (2.33e-1)" "unprognostic (1.36e-2)" "unprognostic (8.19e-3)" "unprognostic (1.96e-1)" "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.9 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.0 0.0 3.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 9.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.2 0.0 133.0 12.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HOXB5 "HOX2, HOX2A" ENSG00000120075 "Homeobox B5" P09067 17 48591257-48593779 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;kidney: 32.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 25.4;Endometrial ciliated cells: 48.8;Glandular and luminal cells: 46.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 28.1" "Region enhanced" "Detected in many" "medulla oblongata: 39.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 28.8;HeLa: 8.7;RPTEC TERT1: 21.7" "Region enriched" "Detected in single" 230 "pons and medulla: 22.9" "Group enriched" "Detected in some" 9 "medulla oblongata: 19.3;spinal cord: 14.3" "HPA043851, HPA074454" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA043851: AB_2732509, HPA074454: AB_2686690" "unprognostic (6.50e-2)" "unprognostic (1.63e-1)" "unprognostic (4.22e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.48e-3)" "unprognostic (7.12e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.47e-1)" "unprognostic (1.47e-3)" "unprognostic (5.10e-2)" "unprognostic (9.64e-2)" "unprognostic (7.61e-3)" "unprognostic (8.08e-3)" "unprognostic (1.35e-1)" "unprognostic (2.86e-2)" "prognostic favorable (8.59e-5)" 4.8 3.9 0.1 2.5 0.0 0.1 1.8 0.0 0.1 6.2 0.0 16.6 1.7 2.3 18.4 0.2 7.4 0.2 0.1 0.1 0.0 32.5 0.6 5.9 0.1 39.1 0.3 0.2 0.7 1.0 0.0 1.2 10.9 1.1 4.9 0.0 0.0 6.9 0.4 0.8 12.2 1.9 24.8 2.6 4.9 0.8 0.0 0.0 0.5 0.2 0.0 2.8 1.5 9.0 2.6 6.5 0.0 3.2 3.2 3.5 0.0 0.0 0.0 0.0 0.0 0.1 3.5 0.0 6.5 3.7 0.7 0.0 0.3 0.0 0.0 0.0 28.8 1.3 8.7 0.0 5.5 0.0 1.4 1.8 0.0 3.9 0.0 1.1 2.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 0.0 3.6 2.3 0.0 1.2 0.0 21.7 2.2 0.0 0.0 0.2 0.0 3.3 0.1 0.6 0.0 6.5 0.9 2.6 0.7 0.4 0.0 0.0 0.0 0.2 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 39.1 0.3 10.9 24.8 0.0 9.0 4.9 0.0 1.1 0.0 0.0 0.9 0.2 0.0 1.2 0.0 0.3 0.3 0.4 0.0 0.0 53.3 0.0 0.0 0.1 13.5 25.4 0.0 0.9 48.8 4.1 6.6 4.2 2.7 0.0 0.0 0.0 3.8 1.1 46.0 0.0 0.0 8.2 0.0 0.7 0.0 0.0 11.4 0.0 4.2 0.8 0.5 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.4 0.0 0.1 7.0 0.5 0.0 0.0 0.0 0.2 4.9 8.6 11.0 0.3 0.3 0.0 0.6 0.0 11.3 0.1 HOXB7 "HOX2, HOX2C" ENSG00000260027 "Homeobox B7" P09629 17 48607232-48633572 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "epididymis: 135.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Distal enterocytes: 131.3;Distal tubular cells: 148.7;Endometrial ciliated cells: 82.9;Glandular and luminal cells: 73.1;Intestinal goblet cells: 77.6;Paneth cells: 67.8;Proximal enterocytes: 140.3;Undifferentiated cells: 63.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 5.6;spinal cord: 13.3;white matter: 7.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 81.9;OE19: 74.7;RPTEC TERT1: 66.5;SK-MEL-30: 84.3" "Region enriched" "Detected in single" 58 "pons and medulla: 5.7" "Region enriched" "Detected in some" 7 "spinal cord: 22.2" HPA049940 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA049940: AB_2616461" "unprognostic (6.76e-2)" "unprognostic (6.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-3)" "unprognostic (1.42e-2)" "unprognostic (1.69e-2)" "unprognostic (8.05e-3)" "unprognostic (9.16e-2)" "unprognostic (9.91e-2)" "unprognostic (7.01e-3)" "unprognostic (7.81e-3)" "unprognostic (1.17e-2)" "unprognostic (1.56e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" "prognostic favorable (2.39e-4)" 13.2 11.0 0.1 3.9 0.1 0.2 12.4 0.0 0.3 21.8 0.1 16.9 1.1 5.2 135.1 0.4 8.7 0.7 0.3 0.1 0.1 30.4 0.4 2.2 2.7 5.6 0.1 0.5 0.8 5.5 0.1 5.8 1.1 2.4 15.9 0.0 0.2 16.9 1.7 3.3 18.1 6.7 13.3 3.0 5.9 1.9 0.3 0.2 0.4 0.2 0.9 7.7 5.5 7.5 48.1 20.6 0.0 0.5 14.2 21.1 0.0 0.0 0.0 0.2 0.8 31.9 0.9 0.9 81.9 19.9 23.9 6.9 0.1 0.0 0.0 22.3 15.1 7.4 15.4 0.0 11.7 0.0 14.8 13.8 6.3 14.2 0.0 3.5 43.8 14.7 8.0 0.3 46.0 12.5 1.0 0.4 0.0 74.7 0.1 0.0 39.2 5.5 66.5 15.8 0.0 0.1 16.0 0.0 84.3 1.1 3.8 4.7 38.1 0.0 24.8 20.5 36.9 2.6 6.3 0.1 0.4 0.0 58.6 0.0 0.0 0.0 1.5 0.0 0.8 0.7 0.2 0.8 0.0 1.4 0.0 0.5 0.0 1.0 0.0 0.7 2.1 0.2 0.1 0.1 0.0 0.3 0.1 0.1 5.6 0.1 1.1 13.3 0.3 7.5 55.4 0.0 0.0 0.0 2.0 5.5 0.9 0.0 0.6 0.0 0.9 1.0 0.3 0.0 0.0 86.5 0.0 6.8 1.6 131.3 148.7 0.1 0.3 82.9 6.3 20.3 36.5 1.3 0.0 1.3 19.3 6.4 0.0 73.1 5.1 0.0 1.4 0.2 11.5 0.0 0.0 77.6 0.0 10.6 5.4 0.2 0.6 2.8 24.9 0.0 1.7 0.0 2.1 0.0 0.0 0.3 67.8 0.0 5.1 0.6 140.3 31.6 0.0 0.0 0.0 3.5 8.9 1.7 20.9 0.2 2.0 1.8 2.6 0.1 63.1 3.5 HOXD10 "HOX4, HOX4D" ENSG00000128710 "Homeobox D10" P28358 2 176108790-176119937 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.6;endometrium 1: 35.9;vagina: 25.0" "Cell type enhanced" "Detected in some" "Adipocytes: 13.0;Collecting duct cells: 14.7;Distal enterocytes: 10.6;Distal tubular cells: 15.6;Endometrial stromal cells: 25.3;Endothelial cells: 13.5;Enteroendocrine cells: 24.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 12.0;HEK 293: 40.3;RPTEC TERT1: 32.3;SCLC-21H: 11.8;SiHa: 18.4;U-251 MG: 14.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 66 "spinal cord: 6.6" HPA065871 Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" No NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA065871: AB_2685573" "unprognostic (4.29e-3)" "unprognostic (2.51e-1)" "unprognostic (2.98e-3)" "unprognostic (1.69e-1)" "unprognostic (1.80e-3)" "unprognostic (6.82e-2)" "unprognostic (1.04e-5)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (2.15e-3)" "unprognostic (4.57e-2)" "unprognostic (4.86e-1)" "unprognostic (1.27e-1)" 2.0 0.1 0.0 0.5 0.0 0.0 2.6 0.0 0.0 20.6 0.0 18.7 0.0 35.9 0.5 0.5 4.1 0.1 0.0 0.0 0.0 19.9 0.0 0.1 0.5 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 16.8 5.8 0.0 0.1 6.7 0.1 1.5 0.1 18.1 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.2 2.2 25.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.2 6.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.1 12.0 0.0 0.0 0.5 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.9 0.0 32.3 0.0 11.8 3.1 18.4 0.0 0.1 2.2 0.0 0.0 2.7 0.0 2.1 1.0 14.4 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.9 6.2 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 14.7 0.0 0.0 0.1 10.6 15.6 0.0 0.0 1.2 25.3 13.5 24.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.8 0.2 1.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.1 1.1 0.0 0.2 0.0 4.4 2.9 HPF1 "C4orf27, FLJ20534" ENSG00000056050 "Histone PARylation factor 1" Q9NWY4 4 169729470-169757944 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.0;Distal tubular cells: 92.0;Extravillous trophoblasts: 61.2;Granulosa cells: 56.4;Hofbauer cells: 56.3;Proximal tubular cells: 63.9;Theca cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043467 Uncertain Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "Microtubules, Cytokinetic bridge" "HPA043467: AB_10793949" "unprognostic (1.09e-1)" "unprognostic (1.15e-2)" "unprognostic (1.72e-2)" "unprognostic (1.47e-1)" "unprognostic (2.70e-1)" "unprognostic (1.09e-1)" "unprognostic (8.68e-3)" "unprognostic (2.74e-2)" "prognostic unfavorable (5.63e-4)" "prognostic favorable (7.47e-4)" "unprognostic (6.34e-2)" "unprognostic (4.55e-1)" "unprognostic (3.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.32e-1)" "unprognostic (5.51e-2)" "unprognostic (1.09e-1)" 19.3 18.6 18.6 16.4 19.9 16.8 21.2 19.6 26.0 19.6 22.0 22.0 12.2 23.3 24.8 15.7 17.1 13.1 22.5 19.2 19.7 18.1 22.1 14.3 21.1 20.2 19.3 22.7 14.4 16.0 19.5 16.8 20.9 17.3 17.7 21.3 13.2 15.7 21.3 19.6 12.8 24.8 19.6 17.5 15.8 14.1 19.6 26.9 18.8 20.9 21.1 16.8 16.8 22.2 33.7 21.0 71.2 37.7 42.6 52.4 30.3 59.9 58.8 72.8 76.7 14.3 35.5 17.5 15.7 39.2 53.3 14.7 49.5 43.6 76.7 55.1 33.7 57.0 30.0 20.5 29.9 48.7 20.1 34.1 43.2 47.1 14.5 44.1 64.1 59.1 43.7 66.2 64.4 27.3 102.7 42.4 29.2 32.2 27.0 44.7 33.8 21.2 41.9 21.9 17.2 63.1 39.7 17.2 56.3 49.1 34.0 43.1 31.3 24.8 39.2 58.4 54.3 31.3 49.8 52.4 68.3 47.0 40.3 19.3 20.0 22.4 28.7 24.0 34.6 22.0 33.0 35.1 26.1 18.1 32.1 33.3 5.3 25.4 23.7 17.9 38.1 21.9 18.6 19.9 19.6 26.0 19.2 19.7 20.2 19.3 20.9 19.6 19.6 22.2 41.6 44.8 26.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 19.9 29.6 0.0 0.0 17.3 27.6 0.0 71.0 14.3 0.0 92.0 45.7 0.0 31.9 36.9 20.1 0.0 0.0 0.0 46.3 61.2 26.1 0.0 21.9 17.7 56.4 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 31.1 0.0 0.0 1.6 0.0 0.0 63.9 15.3 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 16.3 10.5 56.0 0.0 0.0 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.7" "Group enriched" "Detected in many" 18 "granulocytes: 1056.2;Hofbauer cells: 631.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 18.1" "Lineage enriched" "Detected in single" 28 "granulocytes: 18.1" "Group enriched" "Detected in some" 8 "HEL: 46.2;HMC-1: 13.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 250000 "Cluster 46: Basophils - DNA binding" "Cluster 19: Lung - Lung function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 3.4 1.9 2.2 1.1 2.1 1.1 4.0 2.3 3.1 3.5 2.1 5.1 5.8 2.4 2.3 2.9 1.4 6.9 1.8 2.3 2.3 1.5 0.8 9.4 0.6 2.7 2.6 0.5 0.5 0.8 0.4 18.7 2.9 2.6 5.3 0.1 1.5 1.3 0.5 3.3 5.6 3.3 2.6 0.3 2.8 0.7 3.1 2.0 0.3 1.7 0.9 4.8 1.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.2 0.0 0.0 0.0 3.5 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 2.2 2.1 2.3 3.1 2.3 2.3 2.7 2.6 2.9 2.6 3.1 3.5 0.3 12.8 44.7 1.0 0.2 4.1 0.8 0.0 0.6 0.0 0.2 0.8 0.3 0.0 3.7 0.0 0.0 3.6 0.7 0.5 0.0 0.5 0.1 0.2 0.0 2.0 7.1 12.2 0.8 0.0 3.0 3.0 3.6 0.0 1056.2 0.0 0.0 0.0 631.9 0.0 0.6 0.0 0.0 11.4 13.1 0.0 0.3 16.3 3.6 32.8 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.4 2.1 3.9 0.0 0.0 1.5 0.1 0.0 0.6 0.4 0.0 0.1 0.0 5.4 5.5 20.5 0.3 0.9 0.2 HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1308.8;Inhibitory neurons: 893.1;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RT4: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" 1.4 4.2 1.4 0.2 3.5 0.0 0.3 0.0 9.0 1.8 0.0 0.2 0.4 2.1 2.1 0.4 0.5 0.2 0.9 12.5 7.3 0.8 0.0 0.0 0.0 0.1 5.2 0.1 2.2 2.1 1.9 0.0 0.3 0.2 0.1 2.2 0.0 0.2 1.1 0.5 0.4 1.5 0.3 0.0 0.9 0.3 6.1 0.0 2.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 17.3 0.9 0.7 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.5 0.0 9.0 12.5 7.3 0.1 5.2 0.3 0.3 6.1 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.0 0.0 1308.8 0.6 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 3.3 893.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 38.4 0.0 0.9 0.0 968.6 16.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.8 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 HSCB "DNAJC20, HSC20, Jac1" ENSG00000100209 "HscB mitochondrial iron-sulfur cluster cochaperone" Q8IWL3 22 28742039-28757515 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018447, HPA031518" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria, Cytosol" "HPA018447: AB_1853867, HPA031518: AB_2673919" "unprognostic (8.19e-3)" "unprognostic (6.48e-2)" "unprognostic (9.62e-3)" "prognostic favorable (3.78e-4)" "unprognostic (3.30e-1)" "unprognostic (7.02e-2)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "unprognostic (5.83e-2)" "unprognostic (7.38e-3)" "unprognostic (4.44e-1)" "unprognostic (2.81e-1)" "unprognostic (1.54e-3)" "unprognostic (2.19e-1)" "unprognostic (3.39e-1)" "unprognostic (2.12e-1)" "prognostic favorable (8.38e-4)" 8.6 15.3 5.1 6.0 4.9 3.2 9.8 5.3 6.9 12.3 4.7 11.1 8.6 8.0 5.1 7.9 9.3 7.1 8.4 4.8 5.1 11.0 22.0 6.2 11.0 5.6 4.8 12.0 12.5 5.3 7.3 4.5 5.7 10.7 4.5 1.0 18.8 6.2 11.6 7.9 7.3 4.6 5.0 9.0 11.5 4.1 5.4 4.3 8.0 8.1 4.9 10.7 9.0 5.8 13.8 8.5 3.4 5.5 6.3 16.0 6.5 9.9 13.8 14.2 8.8 3.8 4.8 15.1 4.6 5.6 3.4 9.5 6.9 6.3 6.9 14.6 27.2 5.3 5.8 10.7 13.4 9.7 7.7 10.9 13.8 8.0 12.6 7.5 11.0 4.2 8.2 13.1 5.7 20.1 4.3 8.9 8.4 15.0 20.9 8.6 10.8 17.2 15.9 3.9 11.8 10.8 5.4 20.5 25.9 2.9 8.6 5.9 6.0 19.3 10.2 18.6 9.2 18.2 15.9 13.5 13.5 7.1 13.2 10.1 7.8 4.1 6.1 15.2 7.3 13.0 6.2 7.2 11.5 9.6 6.6 8.3 0.4 11.1 12.0 6.0 4.9 5.9 5.1 4.9 5.3 6.9 4.8 5.1 5.6 4.8 5.7 5.0 5.4 5.8 21.4 22.4 19.6 14.4 22.8 11.6 22.2 23.3 40.5 5.5 29.4 37.7 7.8 18.6 23.9 20.2 6.2 16.0 16.7 9.0 29.4 25.0 5.5 12.7 23.3 18.4 19.8 12.6 10.0 28.0 13.5 21.4 11.7 21.6 23.4 17.2 20.3 36.3 27.9 5.0 11.2 14.6 16.2 19.0 14.9 4.3 18.6 19.2 14.2 9.4 22.6 17.4 41.2 16.1 14.2 21.2 11.3 11.7 34.1 20.5 20.2 58.1 24.1 8.1 6.6 19.1 21.9 15.1 16.7 19.8 15.6 13.3 15.9 27.1 21.2 17.2 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.4" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.2 2174.8 0.3 2.1 0.8 0.0 0.1 0.0 0.7 0.2 0.0 7.7 0.0 0.2 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.9 1.0 0.5 0.0 0.0 0.0 0.9 0.5 0.0 0.1 3.6 0.1 0.4 1.0 0.0 1.0 0.0 0.1 0.2 38.7 0.1 0.0 0.2 0.3 2.9 0.2 0.5 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 1.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 3.5 0.0 0.0 0.0 40.6 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 38.8 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 68.9 1.7 0.0 HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 45.4;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "Vesicles, Intermediate filaments" "HPA045745: AB_2679440" "unprognostic (2.16e-1)" "unprognostic (4.32e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-3)" "unprognostic (3.66e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.25e-2)" "unprognostic (7.43e-2)" "unprognostic (3.39e-2)" "unprognostic (6.42e-2)" "unprognostic (3.66e-1)" "prognostic favorable (4.20e-7)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" 7.5 15.4 14.3 7.1 14.6 4.4 11.9 10.9 13.0 10.6 10.7 7.4 6.2 13.2 10.5 7.8 12.6 7.1 15.7 14.0 18.3 10.8 5.1 9.1 9.0 15.0 14.8 22.0 4.9 15.1 11.9 9.1 18.6 9.8 6.9 34.3 7.3 11.1 20.7 8.0 5.7 10.8 9.5 8.0 6.4 13.2 17.0 14.1 26.8 30.5 9.2 7.3 7.1 10.2 11.1 12.6 57.4 19.8 20.7 14.5 14.6 13.8 13.1 17.0 8.9 14.5 18.8 22.7 24.7 12.4 18.8 7.6 31.1 12.1 26.9 4.9 18.9 10.9 7.9 32.5 21.0 17.1 19.2 11.0 20.0 24.1 15.4 21.9 20.9 30.6 23.0 28.2 34.3 27.3 37.8 17.4 29.5 6.4 13.3 36.7 20.4 8.4 16.6 12.0 27.1 20.2 35.0 5.6 39.0 28.5 34.4 10.2 17.5 19.2 22.9 13.9 11.3 44.1 38.1 36.9 22.8 12.3 18.2 21.2 5.0 11.1 3.8 3.4 5.0 5.0 4.1 4.6 2.8 7.5 5.3 5.6 5.5 4.3 6.3 0.0 5.4 4.4 14.3 14.6 10.9 13.0 14.0 18.3 15.0 14.8 18.6 9.5 17.0 10.2 8.9 12.8 16.4 7.8 8.2 4.8 4.6 6.4 8.6 20.2 10.2 8.3 16.7 1.5 8.6 3.7 14.6 6.9 4.4 3.7 5.9 7.9 38.5 11.4 10.5 7.7 9.5 5.7 12.4 6.7 6.6 7.7 3.6 11.0 1.3 38.6 9.3 4.1 12.2 45.4 15.8 3.7 4.1 6.9 3.5 12.2 5.9 10.4 5.4 11.2 6.1 28.4 5.2 15.6 13.0 6.8 2.5 10.1 10.1 5.2 3.9 8.0 13.7 44.2 0.0 8.0 7.8 35.8 30.1 8.8 7.0 8.8 6.6 12.7 4.5 4.8 HSFX1 LW-1 ENSG00000171116 "Heat shock transcription factor family, X-linked 1" Q9UBD0 X 149774068-149776867 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "HPA051700, HPA063040" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA051700: AB_2681578, HPA063040: AB_2732695" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (2.30e-2)" "unprognostic (6.32e-2)" "unprognostic (3.38e-2)" "unprognostic (3.78e-1)" "unprognostic (5.03e-2)" "unprognostic (3.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.47e-1)" "unprognostic (1.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.46e-1)" "unprognostic (3.10e-1)" 0.8 0.8 1.5 0.3 1.8 0.0 1.1 1.9 2.6 1.7 2.8 1.8 0.5 1.3 3.3 1.2 1.5 0.8 1.9 2.0 1.4 1.0 1.0 0.9 0.4 1.5 1.5 3.1 1.0 0.8 1.2 1.2 2.2 2.0 0.1 0.7 1.3 0.6 1.3 1.2 1.0 0.4 1.0 2.5 1.0 3.4 1.8 0.1 1.5 0.0 0.4 1.4 1.5 1.8 0.0 1.1 0.0 0.4 1.4 0.9 0.2 0.2 0.0 0.2 0.0 0.8 0.7 0.7 1.2 0.1 0.7 0.0 0.6 0.2 0.1 0.1 0.0 0.2 0.5 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.6 1.1 0.3 0.0 0.0 0.2 0.1 1.3 0.1 0.5 0.3 0.1 0.6 0.3 0.8 0.0 1.0 0.5 0.5 0.2 0.1 0.0 0.2 0.8 0.1 0.2 0.2 0.0 0.6 0.2 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 1.8 1.9 2.6 2.0 1.4 1.5 1.5 2.2 1.0 1.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSFX2 ENSG00000268738 "Heat shock transcription factor family, X-linked 2" Q9UBD0 X 149592512-149595314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 12.3" "Cell type enriched" "Detected in single" 16 "Cardiomyocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;HEK 293: 1.1;hTCEpi: 1.5;MCF7: 1.4;U-138 MG: 1.5" "HPA051700, HPA063040" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA051700: AB_2681578, HPA063040: AB_2732695" "unprognostic (7.64e-2)" "unprognostic (6.92e-3)" "unprognostic (2.00e-1)" 0.3 0.4 0.8 0.2 1.0 0.0 0.6 0.9 2.2 0.5 1.0 0.6 0.5 0.6 0.2 0.4 1.0 0.0 1.2 0.7 0.1 0.5 0.5 0.6 0.1 0.5 0.3 1.0 0.4 1.3 0.4 0.4 0.4 0.9 0.5 1.0 1.0 1.4 0.7 1.2 0.3 0.7 0.0 1.1 0.4 12.3 0.1 0.6 0.5 2.1 0.2 0.3 0.5 0.8 0.5 0.0 1.1 0.6 0.0 0.2 0.0 0.2 0.5 0.2 0.6 0.0 0.0 0.1 0.2 0.3 0.0 1.0 0.0 0.3 0.1 0.0 1.1 0.0 0.4 0.0 0.0 0.1 0.3 0.5 1.5 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.9 2.2 0.7 0.1 0.5 0.3 0.4 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSH2D "ALX, FLJ14886, HSH2" ENSG00000196684 "Hematopoietic SH2 domain containing" Q96JZ2 19 16134028-16158575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.0;lymphoid tissue: 37.7" "Cell type enhanced" "Detected in many" "B-cells: 78.5;dendritic cells: 101.3;Gastric mucus-secreting cells: 40.2;NK-cells: 82.4;Plasma cells: 134.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 232.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.0;HL-60: 43.5;HMC-1: 56.4;NB-4: 140.1;RPMI-8226: 63.2;U-266/84: 41.9;U-937: 137.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036616 Approved "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA036616: AB_10671962" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (9.46e-6)" "unprognostic (1.06e-1)" "unprognostic (5.50e-3)" "unprognostic (5.21e-3)" "unprognostic (9.35e-2)" "unprognostic (4.78e-2)" "unprognostic (4.21e-3)" "unprognostic (9.96e-2)" "unprognostic (1.57e-2)" "unprognostic (2.22e-2)" "prognostic unfavorable (6.49e-6)" "unprognostic (9.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.21e-2)" "prognostic favorable (3.47e-5)" 1.6 0.7 0.5 16.8 1.1 47.0 3.3 1.1 1.1 3.0 1.2 9.8 12.7 1.3 1.8 1.7 3.2 5.4 0.4 0.5 0.4 1.5 2.2 5.6 27.2 1.5 0.7 0.5 4.3 2.3 4.0 1.5 1.1 5.1 9.3 0.3 9.5 2.9 0.4 0.4 20.5 1.0 0.7 37.7 12.7 0.4 1.0 8.7 2.6 1.2 35.7 7.5 0.7 2.8 15.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 2.2 21.3 41.0 0.6 0.0 0.8 0.7 0.0 0.6 0.0 2.3 0.1 0.6 0.5 2.6 0.0 43.5 56.4 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 37.4 0.0 9.0 0.1 140.1 0.0 5.5 0.0 3.0 0.0 63.2 0.4 5.6 0.1 0.1 0.0 1.3 0.3 0.0 0.3 15.9 0.2 0.1 0.1 0.2 0.2 5.7 41.9 23.6 0.2 137.3 0.0 232.1 15.5 100.9 17.1 22.0 15.8 56.4 7.6 11.2 25.5 35.8 6.9 9.2 182.6 85.2 38.8 7.6 13.0 16.7 0.5 1.1 1.1 1.1 0.5 0.4 1.5 0.7 1.1 0.7 1.0 2.8 1.0 3.2 8.9 0.0 78.5 0.3 1.2 3.0 0.6 0.0 3.6 1.9 0.6 5.7 11.3 5.5 0.0 2.6 101.3 18.9 0.0 6.7 0.0 4.5 1.5 0.8 8.4 32.2 0.5 5.1 4.1 0.7 40.2 7.9 6.3 0.1 1.4 0.6 1.1 0.0 0.4 19.1 2.0 3.4 2.4 0.1 0.0 7.3 10.6 1.0 10.7 0.0 82.4 1.0 0.3 9.7 18.0 0.0 134.0 2.6 17.9 0.3 7.9 0.0 0.0 1.1 0.7 0.1 0.5 0.1 0.1 3.4 31.0 0.2 9.3 4.1 HSPA1A "HSP70-1, HSPA1" ENSG00000204389 "Heat shock protein family A (Hsp70) member 1A" P0DMV8 6 31815543-31817946 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 7514.5;Langerhans cells: 2690.4;Urothelial cells: 3444.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 64 "cerebral cortex: 403.6" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 6.8;monocytes: 3.6;T-cells: 3.0" "Cell line enriched" "Detected in some" 8 "HEK 293: 4450.4" "CAB017451, CAB032815, HPA052504" Supported Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA Yes 47000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" Cytosol "CAB017451: AB_10013742, CAB032815: AB_627759, HPA052504: AB_2681854" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (6.17e-3)" "unprognostic (2.47e-2)" "unprognostic (1.74e-2)" "unprognostic (8.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" "unprognostic (6.48e-2)" "unprognostic (4.12e-2)" "unprognostic (1.51e-1)" 640.5 350.5 3.5 12.7 3.8 0.0 167.2 6.3 403.6 414.1 3.4 497.7 0.0 209.7 15.9 452.9 194.6 5.9 927.7 4.3 3.7 745.9 1116.2 1055.0 9.1 5.4 5.1 369.7 308.2 1.1 474.3 12.0 4.0 427.7 4.2 6.5 111.5 0.5 294.4 257.3 174.4 2.2 3.8 451.9 483.2 98.0 3.7 2.5 340.2 0.3 2.3 569.2 553.7 6.1 0.2 524.1 0.0 0.1 20.1 14.4 0.0 0.3 0.0 0.0 0.0 1.6 0.7 0.0 122.9 28.7 0.0 0.4 0.0 34.1 0.0 6.9 4450.4 0.0 1.7 3.1 0.0 1.1 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 33.4 0.0 0.5 0.7 0.0 0.0 16.6 5.3 0.0 0.1 4.1 0.0 49.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.3 2.3 3.2 1.1 3.6 0.7 0.6 1.6 1.4 0.3 0.2 0.7 0.6 6.8 0.8 2.0 0.3 3.0 0.4 3.5 3.8 6.3 403.6 4.3 3.7 5.4 5.1 4.0 3.8 3.7 6.1 1537.0 147.4 97.0 427.4 312.4 362.4 7514.5 125.5 968.7 305.3 782.0 844.3 1010.7 81.5 109.3 126.9 379.5 43.2 148.1 634.6 41.1 86.8 81.0 534.7 488.1 1049.0 469.2 64.0 9.7 21.6 154.1 1208.6 592.8 753.4 445.4 18.1 123.5 95.2 270.4 205.3 11.4 560.1 114.0 319.0 2690.4 49.5 603.0 1715.2 839.6 398.2 126.6 768.2 15.5 17.1 207.0 39.5 668.8 160.6 1173.3 1404.1 68.4 72.9 177.2 690.2 151.2 443.4 1802.0 65.4 148.8 1105.8 336.3 104.3 1382.2 285.6 454.9 3444.4 HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3007.4;Urothelial cells: 1619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 204.3" "CAB008640, HPA052504" Approved Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" Nucleoplasm "CAB008640: AB_1617331, HPA052504: AB_2681854" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (4.23e-3)" "unprognostic (3.23e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-3)" "unprognostic (9.50e-2)" "unprognostic (3.45e-1)" "unprognostic (4.42e-2)" "unprognostic (6.92e-2)" "unprognostic (4.88e-2)" "unprognostic (5.74e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-3)" "unprognostic (4.69e-2)" "unprognostic (5.99e-2)" 526.3 340.1 0.7 0.4 1.3 0.0 126.0 1.6 5.6 475.3 0.6 361.2 0.0 154.0 9.1 375.2 231.5 2.3 718.3 1.1 1.9 555.5 685.4 845.3 0.0 0.8 1.0 682.2 336.5 3.3 438.2 0.0 1.2 303.6 0.5 2.6 94.8 0.3 159.9 299.0 139.1 0.0 0.4 274.7 372.0 93.8 1.5 0.0 289.9 0.0 0.0 415.3 503.3 1.2 0.4 24.1 0.4 0.2 1.1 0.0 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 15.4 0.0 0.5 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 204.3 0.0 3.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 1.6 0.0 0.0 0.3 3.2 0.0 0.4 41.5 0.4 0.4 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.3 1.6 5.6 1.1 1.9 0.8 1.0 1.2 0.4 1.5 1.2 563.2 112.2 75.0 140.7 242.7 239.2 3007.4 63.2 630.0 44.6 509.4 403.9 512.3 40.0 73.7 69.9 131.3 82.7 82.8 542.8 19.6 45.5 1.9 434.9 380.2 446.2 318.6 57.9 2.7 15.6 140.8 585.8 595.8 710.4 346.8 14.1 25.7 17.7 142.0 47.1 2.8 426.3 61.1 84.4 1140.4 9.8 220.6 627.1 642.1 126.5 17.7 192.4 1.0 5.5 61.8 21.4 524.1 54.9 967.0 584.2 159.1 38.3 75.0 144.2 105.2 226.4 846.5 15.2 46.4 904.0 221.9 259.7 604.6 116.7 400.5 1619.4 HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 165.7;Fibroblasts: 125.2;Leydig cells: 271.8;Peritubular cells: 220.4;Smooth muscle cells: 102.6;Theca cells: 311.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1774.3;ASC TERT1: 742.0;HHSteC: 599.9;HSkMC: 700.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nucleoli,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoli, Golgi apparatus" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" 650.0 414.0 37.3 45.4 40.6 0.4 394.9 32.5 49.2 581.9 26.1 699.9 28.1 565.1 101.6 112.3 495.1 97.9 1463.9 30.0 43.6 69.0 42.3 126.6 5.7 76.7 48.5 455.2 50.5 4.2 17.5 40.2 73.7 271.2 44.0 21.1 115.9 194.7 2969.8 39.1 180.0 278.2 50.8 15.7 362.1 60.6 53.8 6.2 99.5 1759.1 2.7 537.3 290.6 49.3 0.6 0.7 2.1 2.5 1774.3 742.0 1.2 83.0 1.3 4.9 9.3 1.1 0.4 0.7 0.6 252.4 0.0 0.2 0.4 0.7 3.9 0.9 0.5 0.4 1.3 0.5 599.9 0.2 0.9 700.3 0.0 19.1 0.9 2.2 5.4 0.3 0.5 1.0 0.2 0.3 0.4 1.9 1.2 2.3 0.6 1.5 0.5 0.7 0.0 0.1 0.8 0.7 0.1 0.2 0.7 0.3 0.3 0.5 0.1 153.2 0.9 17.3 0.6 1.0 2.8 0.3 20.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 40.6 32.5 49.2 30.0 43.6 76.7 48.5 73.7 50.8 53.8 49.3 11.1 3.2 0.6 1.6 0.1 1.8 0.4 0.0 3.4 7.8 0.5 0.5 29.7 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 0.1 27.0 4.9 165.7 3.6 0.0 5.2 0.2 0.0 2.5 125.2 4.1 3.5 0.0 3.6 17.5 0.3 5.0 0.0 0.5 0.0 0.0 0.3 3.6 18.9 271.8 2.7 1.8 0.0 0.6 44.5 0.0 0.0 0.1 0.2 0.0 220.4 0.1 0.4 0.0 0.4 0.0 2.8 26.3 38.0 102.6 2.3 1.4 1.9 2.0 4.8 1.8 311.0 0.0 0.5 HSPB9 CT51 ENSG00000260325 "Heat shock protein family B (small) member 9" Q9BQS6 17 42122804-42123352 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 17.8" "Group enriched" "Detected in some" 5 "Early spermatids: 375.3;Late spermatids: 1017.0" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA053091 Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA053091: " "unprognostic (2.36e-1)" "unprognostic (2.63e-1)" "unprognostic (8.35e-2)" "unprognostic (1.99e-2)" "unprognostic (5.67e-2)" "unprognostic (8.37e-2)" "unprognostic (2.30e-2)" "unprognostic (3.42e-6)" "unprognostic (2.31e-1)" "unprognostic (5.13e-2)" "unprognostic (3.82e-1)" "unprognostic (8.62e-2)" "unprognostic (3.36e-3)" "unprognostic (3.68e-4)" "unprognostic (4.78e-2)" "unprognostic (4.01e-1)" "unprognostic (1.24e-1)" 0.4 0.2 1.3 0.4 1.4 0.6 0.2 1.6 1.7 0.2 0.9 0.3 0.3 0.2 0.0 0.1 0.7 0.6 0.2 1.2 1.3 0.5 3.6 0.2 0.4 1.4 1.2 1.3 4.8 0.2 0.5 0.2 1.4 0.5 0.0 0.0 2.9 0.5 1.5 0.4 0.4 0.1 1.2 0.5 0.4 17.8 1.4 0.0 0.2 1.0 0.0 0.2 0.2 1.7 0.2 0.2 0.3 0.9 0.0 0.0 3.3 0.0 0.0 0.0 0.3 1.0 0.1 0.3 0.1 0.0 0.1 0.0 0.4 0.2 0.0 0.3 3.0 0.5 1.2 0.4 0.0 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 0.2 0.0 0.4 0.3 1.1 0.1 0.3 0.0 0.1 0.2 1.0 0.0 0.7 1.4 0.3 0.0 1.5 0.2 0.1 0.2 0.1 0.4 0.7 0.0 0.6 0.2 0.6 0.3 0.6 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.3 1.4 1.6 1.7 1.2 1.3 1.4 1.2 1.4 1.2 1.4 1.7 0.7 0.0 0.0 0.0 0.0 0.4 0.5 0.1 0.6 0.6 0.6 0.5 0.6 2.8 0.0 0.0 2.1 3.2 0.2 0.4 19.6 0.0 375.3 0.5 0.3 0.6 0.0 0.0 0.1 1.1 0.8 0.7 0.0 0.3 0.0 0.5 1.8 15.3 0.2 3.3 0.1 0.7 0.0 0.8 0.4 1017.0 7.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.3 6.8 0.0 0.4 0.6 0.9 0.1 0.4 0.0 0.8 0.3 127.3 4.5 0.1 0.3 0.3 0.2 0.6 0.3 0.2 HSPBP1 FES1 ENSG00000133265 "HSPA (Hsp70) binding protein 1" Q9NZL4 19 55262223-55280381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 270.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005865, HPA070398, HPA071444" Supported Approved Vesicles,Centrosome,Cytosol NA NA 19000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Vesicles, Centrosome" "CAB005865: AB_304116, HPA070398: , HPA071444: AB_2686396" "unprognostic (3.07e-2)" "unprognostic (6.36e-2)" "unprognostic (5.41e-2)" "unprognostic (8.05e-2)" "unprognostic (9.24e-2)" "unprognostic (1.43e-1)" "unprognostic (3.71e-3)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (1.52e-1)" "unprognostic (6.20e-3)" "unprognostic (7.23e-2)" "unprognostic (4.28e-3)" "unprognostic (2.44e-2)" "unprognostic (2.62e-1)" "unprognostic (9.45e-2)" "unprognostic (2.14e-2)" 24.6 29.0 41.4 14.5 50.8 16.6 25.4 41.4 60.5 29.8 34.1 34.9 15.7 39.3 5.2 42.1 38.4 6.2 46.9 41.9 40.3 38.8 37.9 23.9 12.3 40.3 41.8 34.3 27.4 18.9 26.8 8.3 38.6 29.3 6.7 7.3 25.2 10.4 46.9 33.7 24.0 8.0 39.2 21.0 28.9 32.5 39.6 9.6 27.1 16.9 8.1 33.3 29.7 39.5 86.9 150.0 27.1 38.6 15.3 14.3 78.8 44.3 17.8 45.0 38.3 85.5 57.7 56.1 42.1 24.3 27.0 59.0 33.1 43.9 11.6 48.4 270.8 74.9 48.2 79.7 34.1 72.3 38.1 18.5 39.4 44.6 20.9 19.4 22.5 46.5 61.6 31.1 15.8 80.3 65.4 64.2 95.6 75.2 125.8 63.7 41.7 121.0 30.4 54.8 71.0 108.0 54.2 54.2 46.9 14.4 41.7 56.4 29.8 50.3 55.0 29.4 83.1 48.4 126.9 60.0 57.6 62.6 56.6 2.0 25.7 7.2 39.1 45.4 40.9 53.9 42.2 44.7 52.9 64.3 42.1 41.1 1.7 44.2 39.6 29.3 43.3 25.1 41.4 50.8 41.4 60.5 41.9 40.3 40.3 41.8 38.6 39.2 39.6 39.5 11.8 9.6 11.5 5.5 15.6 26.8 39.7 55.5 29.6 15.9 20.1 20.8 13.2 34.3 35.1 35.0 6.2 48.0 11.6 46.4 72.4 62.5 13.4 69.4 15.2 18.5 22.6 18.1 8.6 46.1 57.0 22.0 25.5 13.4 10.8 20.0 10.4 23.9 39.1 13.5 11.6 31.7 44.7 11.3 13.7 16.0 19.6 11.9 17.8 3.7 28.2 14.9 21.6 6.0 7.3 42.6 44.4 17.7 27.3 29.5 25.5 62.5 119.8 14.8 26.3 24.2 31.9 39.0 28.8 27.9 29.5 37.5 17.1 16.6 58.9 35.2 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 7.6;parathyroid gland: 13.1;testis: 8.7" "Cell type enhanced" "Detected in some" "Early spermatids: 7.0;Excitatory neurons: 5.9;Inhibitory neurons: 24.2;Spermatocytes: 13.1" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.3;hTCEpi: 10.1;hTERT-HME1: 33.4;LHCN-M2: 13.5;U-251 MG: 9.6;U-87 MG: 10.2;WM-115: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" 0.5 0.2 2.4 0.9 1.4 0.3 0.3 0.0 2.5 0.4 0.4 0.6 0.5 0.2 0.1 0.7 0.2 0.9 0.1 2.7 7.1 0.1 0.4 0.2 0.6 1.5 3.2 0.1 0.2 13.1 0.1 0.3 1.9 0.2 0.9 0.1 0.3 0.1 0.9 0.5 1.4 0.3 0.5 1.1 0.7 8.7 7.6 0.2 0.1 0.5 0.3 2.3 0.6 0.8 0.3 0.0 0.0 0.0 0.2 0.9 0.0 0.7 0.3 0.7 1.0 0.0 1.2 0.0 0.0 0.1 2.0 4.7 1.3 11.3 2.8 0.0 0.2 0.0 0.0 0.0 5.1 0.0 0.6 7.8 10.1 3.3 33.4 6.3 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.2 1.2 0.0 1.6 1.0 0.1 0.0 0.0 1.2 0.4 0.0 0.5 0.0 5.4 0.6 0.0 0.2 0.3 6.1 0.0 0.1 9.6 0.0 0.0 0.0 10.2 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.4 0.0 2.5 2.7 7.1 1.5 3.2 1.9 0.5 7.6 0.8 0.1 0.0 0.0 0.7 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.0 1.7 0.0 24.2 0.0 2.0 2.2 0.0 2.7 0.0 2.5 0.0 0.0 0.4 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.1 13.1 1.3 0.0 0.1 0.1 0.2 0.0 0.0 0.3 HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43450989-43453989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 97.7;HUVEC TERT2: 106.7;U-251 MG: 99.2;WM-115: 105.5" "Low region specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: AB_10795374" "prognostic favorable (9.18e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.68e-2)" "unprognostic (3.86e-1)" "unprognostic (4.40e-2)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (2.75e-5)" "unprognostic (5.10e-2)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "prognostic favorable (2.72e-5)" 31.7 22.8 28.1 9.3 29.2 12.1 19.3 29.6 36.3 23.4 27.9 21.3 44.1 23.3 15.4 15.0 24.2 18.7 20.8 27.0 31.2 29.5 44.6 23.0 11.3 30.9 28.9 42.1 53.7 25.2 14.6 10.5 30.9 19.8 12.3 4.1 35.3 47.0 20.8 16.2 34.4 13.2 30.0 12.2 23.9 3.9 28.4 8.8 19.1 10.2 9.2 17.4 15.3 32.4 58.7 7.3 2.2 3.5 9.8 15.1 0.2 48.4 35.7 52.6 34.3 24.2 97.7 0.0 4.1 29.7 25.1 10.9 0.0 45.8 21.6 15.2 20.5 10.2 25.0 0.0 58.8 0.0 0.0 9.4 12.4 64.0 0.0 56.3 106.7 0.5 1.2 0.0 34.5 1.2 9.6 8.8 11.1 5.6 15.5 46.0 0.0 0.3 37.5 2.2 27.2 20.3 56.0 30.4 13.2 8.7 9.2 72.0 59.5 3.7 0.0 12.4 99.2 0.0 0.0 0.0 4.1 13.4 105.5 10.6 1.7 3.7 4.2 1.3 5.5 4.3 7.1 3.3 5.8 5.3 6.6 2.0 0.1 7.5 1.8 29.9 0.7 4.0 28.1 29.2 29.6 36.3 27.0 31.2 30.9 28.9 30.9 30.0 28.4 32.4 29.8 19.2 64.4 5.9 16.1 28.0 45.2 22.8 51.8 16.9 41.0 65.3 0.4 65.8 23.0 57.0 10.4 18.6 19.2 56.6 45.0 106.7 1.2 9.9 23.6 23.2 69.5 21.5 1.4 86.1 115.9 45.7 25.5 18.7 43.2 33.5 25.0 59.0 29.8 8.4 1.9 89.1 16.2 8.5 31.0 4.5 31.7 23.5 40.9 1.9 15.8 45.0 8.2 4.5 4.8 109.6 97.0 30.5 41.7 33.7 232.5 146.9 12.4 16.7 26.3 31.3 58.2 1.4 3.0 27.3 22.0 12.0 12.3 49.8 47.6 38.4 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 219.3;urinary bladder: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 612.2;Alveolar cells type 2: 561.6;Endothelial cells: 240.8;Langerhans cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 158.3;Karpas-707: 459.7;RPMI-8226: 148.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 87.9 23.6 9.1 44.6 9.6 117.1 32.4 7.9 12.0 11.2 9.9 17.7 16.8 23.9 3.5 11.0 26.2 56.4 39.1 8.8 9.9 43.9 67.1 219.3 38.3 12.3 8.7 13.0 11.1 8.3 9.3 27.8 10.2 22.2 18.1 10.5 18.0 6.3 15.1 17.9 22.6 23.4 10.0 55.9 21.5 5.6 15.4 28.4 30.8 12.8 32.9 215.3 12.5 10.2 46.3 0.5 7.9 0.2 2.0 4.4 9.7 8.6 91.6 21.8 62.0 14.0 49.8 39.6 130.3 3.8 99.3 8.9 1.7 0.4 45.6 123.8 0.1 3.8 1.4 62.0 158.3 1.3 23.9 55.7 4.0 13.7 20.3 2.0 10.7 4.9 15.0 459.7 1.5 3.3 0.5 34.9 3.1 0.5 24.7 1.0 0.2 148.5 36.8 0.3 0.3 1.1 61.2 3.3 94.5 3.7 6.9 2.8 34.3 22.3 1.9 12.3 0.8 137.4 142.7 25.5 35.1 26.3 32.6 5.0 28.3 5.2 5.3 25.8 9.8 3.8 4.0 6.3 24.7 1.5 1.9 3.8 40.8 15.2 17.0 14.1 6.1 20.8 9.1 9.6 7.9 12.0 8.8 9.9 12.3 8.7 10.2 10.0 15.4 10.2 150.3 612.2 561.6 0.3 31.7 85.3 22.2 62.6 28.5 0.0 50.2 24.9 1.1 21.5 133.5 3.7 0.0 1.1 28.9 2.9 0.0 176.8 2.0 14.1 15.5 240.8 2.4 1.3 0.5 98.7 3.3 136.6 13.7 29.8 139.8 0.1 48.2 12.1 86.7 0.0 0.4 0.7 32.6 53.6 232.6 1.3 4.7 168.3 76.5 7.5 101.9 4.6 5.2 0.5 0.2 113.7 0.3 1.5 57.6 27.1 0.3 15.0 83.2 0.4 6.6 38.2 57.6 0.8 1.6 4.3 69.3 1.2 28.8 0.5 1.6 14.1 ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 151.9;dendritic cells: 164.6;Hepatocytes: 168.8;NK-cells: 313.1;Plasma cells: 137.2;T-cells: 183.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Cell line enhanced" "Detected in many" "Karpas-707: 324.6;NB-4: 222.3;RPMI-8226: 257.6;U-266/84: 188.8;U-937: 179.0" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" 18.9 7.4 4.8 50.4 4.6 206.5 10.0 4.5 6.4 4.9 4.4 16.1 15.1 3.6 2.8 7.6 6.2 9.0 18.1 4.5 4.6 11.9 73.2 16.0 72.2 4.9 5.0 2.9 15.2 2.9 1.0 4.6 5.0 6.8 11.0 0.9 15.2 2.9 18.0 4.3 28.1 4.4 5.2 85.8 19.5 2.1 5.2 48.6 6.8 11.9 50.6 14.1 4.4 4.6 12.4 5.8 4.2 13.1 6.8 5.3 7.3 7.5 5.1 5.9 5.2 5.3 8.1 0.2 24.9 6.2 0.1 5.4 0.2 5.5 2.0 106.2 3.7 23.8 5.4 22.6 3.4 96.7 102.1 4.8 4.4 7.0 2.6 6.4 2.9 57.1 13.0 324.6 6.9 24.0 13.9 222.3 3.2 31.7 38.3 11.1 2.7 257.6 6.2 11.2 1.3 5.6 6.5 20.4 17.3 1.9 17.7 23.9 4.6 28.0 3.0 31.2 7.6 20.7 188.8 37.3 20.2 179.0 22.1 193.6 395.4 872.4 362.7 287.8 436.2 280.1 343.0 331.7 327.5 271.7 301.5 283.9 1948.5 380.1 417.4 52.9 436.3 614.5 4.8 4.6 4.5 6.4 4.5 4.6 4.9 5.0 5.0 5.2 5.2 4.6 22.6 3.2 29.7 0.7 151.9 8.2 6.5 7.0 10.2 0.3 23.1 20.6 0.1 21.5 9.8 5.5 0.0 12.0 164.6 49.1 62.6 16.9 7.7 10.7 9.4 19.2 5.4 37.4 0.2 35.4 24.7 10.2 16.8 9.9 30.4 5.5 31.1 168.8 24.0 1.7 0.1 33.2 4.1 70.0 50.4 10.0 6.2 52.9 55.2 1.0 127.7 6.4 313.1 0.0 0.1 23.2 43.8 4.1 137.2 12.3 79.9 54.4 9.0 1.2 0.0 7.3 10.7 5.7 0.7 8.3 8.4 4.7 183.3 5.4 36.4 10.2 ID2 "bHLHb26, GIG8" ENSG00000115738 "Inhibitor of DNA binding 2" Q02363 2 8678845-8684461 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1209.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 2393.2;monocytes: 1987.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1038.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 731.4;HEK 293: 459.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027612 Approved "Nucleoplasm,Nuclear bodies,Centrosome" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nuclear bodies" Centrosome "HPA027612: AB_10599729" "unprognostic (2.53e-1)" "unprognostic (8.16e-3)" "unprognostic (8.51e-2)" "unprognostic (6.66e-2)" "unprognostic (2.24e-1)" "prognostic favorable (9.95e-4)" "unprognostic (4.39e-2)" "unprognostic (6.31e-2)" "unprognostic (1.95e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (5.98e-2)" "unprognostic (2.42e-2)" "unprognostic (1.74e-1)" "unprognostic (1.38e-3)" "unprognostic (1.92e-3)" 160.8 175.9 86.6 73.9 88.5 390.3 82.6 83.8 118.2 97.4 68.5 149.9 99.1 69.7 21.0 35.3 108.3 150.8 177.4 89.6 86.8 128.2 562.5 108.1 92.6 80.2 82.9 213.1 60.1 1209.7 65.7 70.3 85.2 125.1 124.7 69.7 114.3 142.4 18.9 69.6 99.4 85.3 81.4 107.4 66.7 13.8 90.1 73.8 223.5 41.2 47.4 110.2 76.2 95.8 2.0 132.4 56.0 68.6 86.8 13.9 208.5 156.6 18.3 68.4 29.1 266.0 7.3 4.1 175.1 262.5 16.9 115.9 36.0 1.0 20.7 731.4 459.5 101.3 81.7 333.9 24.8 76.5 266.3 23.4 3.1 30.5 1.9 19.2 1.4 6.7 6.2 113.9 109.1 45.3 7.8 9.0 102.4 338.5 102.9 9.7 38.4 75.6 71.3 60.5 103.5 146.6 8.4 117.8 12.1 142.0 19.3 44.9 27.5 83.9 14.5 126.5 9.4 8.9 7.9 88.7 106.6 230.2 46.5 110.3 76.0 1038.0 356.7 221.7 214.2 3.6 108.1 251.9 223.8 1.6 133.7 262.1 96.6 880.8 248.9 10.3 9.2 200.1 86.6 88.5 83.8 118.2 89.6 86.8 80.2 82.9 85.2 81.4 90.1 95.8 429.9 141.1 237.9 316.7 41.4 131.3 143.0 494.8 138.9 9.8 231.2 218.4 179.5 316.0 211.2 101.2 16.7 260.3 604.5 337.7 555.7 471.0 12.0 601.1 344.6 281.1 425.9 59.8 23.5 160.3 142.4 276.0 189.1 647.2 973.6 17.1 487.6 554.7 700.3 6.7 13.8 548.0 494.4 415.8 2393.2 21.7 124.2 528.4 282.8 15.9 1987.9 519.9 1070.1 26.7 3.2 69.6 301.9 32.7 86.0 130.1 231.3 264.1 66.7 27.4 19.7 166.6 185.6 2.1 39.9 97.6 104.6 666.0 690.0 16.7 323.1 51.3 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.7;placenta: 110.9" "Cell type enriched" "Detected in many" 11 "monocytes: 2612.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.0" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.0" "Cell line enriched" "Detected in some" 7 "EFO-21: 61.8" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 9.8 0.7 0.6 40.5 0.4 0.7 2.0 0.4 0.8 7.2 1.0 5.3 10.3 10.2 1.2 1.3 2.6 6.2 1.8 0.4 0.6 1.7 2.4 25.9 58.7 0.7 0.3 1.2 1.2 0.2 0.1 110.9 0.5 2.0 8.2 1.3 1.9 3.0 8.1 1.3 8.4 2.4 0.4 23.0 5.8 1.1 0.8 31.2 4.0 0.6 31.5 9.1 0.5 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 7.6 4.8 0.3 0.8 0.0 61.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.1 0.2 0.2 0.0 0.3 0.0 32.5 1.3 465.0 0.1 1.4 0.1 0.2 0.1 0.0 26.4 0.3 0.1 0.2 4.9 0.1 0.1 0.3 0.1 1.2 0.6 0.4 0.4 0.8 0.4 0.6 0.7 0.3 0.5 0.4 0.8 0.6 24.9 0.0 0.5 0.7 4.4 0.4 0.2 18.3 0.0 0.0 0.5 0.1 0.3 0.0 76.0 0.0 0.0 0.0 0.3 8.3 0.0 4.4 3.7 70.1 23.0 6.9 0.0 0.0 0.2 8.1 0.0 0.3 0.0 223.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 2.0 3.7 28.1 1.8 0.0 13.6 0.0 0.0 2612.3 3.0 0.0 0.0 0.1 0.4 0.0 0.4 2.4 0.5 0.0 0.0 33.3 0.2 0.0 1.2 8.4 0.0 0.1 0.1 0.6 0.0 1.3 0.0 1.3 2.0 IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" Cytosol "CAB016293: AB_627775, HPA002134: AB_1079099, HPA073514: " "unprognostic (7.23e-3)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (7.70e-3)" "unprognostic (1.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (5.07e-2)" "unprognostic (4.08e-1)" "unprognostic (7.97e-2)" "unprognostic (1.14e-1)" 95.7 37.9 13.5 114.5 17.5 35.5 72.8 14.3 14.1 56.8 9.1 38.3 23.8 76.5 22.7 63.6 54.2 100.6 35.0 13.7 20.3 30.1 27.7 68.2 140.6 29.9 22.7 76.8 16.7 9.7 9.3 66.7 27.0 26.5 45.0 7.7 63.7 32.0 16.8 58.8 47.9 87.3 23.6 107.8 30.7 18.8 23.8 116.8 37.4 32.6 133.1 113.6 52.8 26.2 43.5 3.2 14.4 0.6 97.4 319.5 0.4 89.9 238.0 245.7 324.2 0.0 54.1 251.7 75.4 55.3 79.2 122.2 2.2 91.1 97.7 78.4 1.1 64.9 17.2 0.1 181.8 22.8 4.2 302.4 159.5 126.5 177.8 117.8 262.8 218.1 1.4 179.4 138.6 0.0 302.2 21.1 38.4 0.0 32.5 140.6 91.4 295.0 34.4 16.1 6.6 0.1 117.7 1.0 259.5 56.9 0.4 26.3 150.2 63.1 29.7 179.9 38.2 165.8 82.8 235.5 181.2 72.7 155.7 9.1 67.7 0.4 57.5 66.4 51.9 88.4 54.3 59.4 68.3 94.6 33.9 43.3 164.4 91.6 65.3 51.1 82.1 63.8 13.5 17.5 14.3 14.1 13.7 20.3 29.9 22.7 27.0 23.6 23.8 26.2 378.4 38.5 54.6 4.2 217.8 95.0 110.7 197.6 174.8 0.4 47.8 43.8 10.7 37.1 130.7 42.3 0.0 3.4 278.3 7.9 1.9 38.0 4.9 41.9 219.1 286.8 12.1 38.7 1.3 47.8 2.9 207.8 9.7 68.0 138.3 27.7 137.4 3.0 214.2 0.0 2.2 19.9 79.3 163.8 135.0 9.8 117.4 187.2 83.6 116.2 202.4 30.8 329.6 37.2 20.7 47.1 23.5 53.0 143.3 32.6 7.9 4.9 76.6 1.4 85.5 185.3 132.7 2.4 13.2 92.6 68.2 3.3 219.2 70.6 26.4 107.5 IFI35 IFP35 ENSG00000068079 "Interferon induced protein 35" P80217 17 43006740-43014456 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 122.4;Paneth cells: 116.7;Proximal enterocytes: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 204.5;BJ hTERT+ SV40 Large T+ RasG12V: 299.2;GAMG: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045946, HPA075580" Approved Supported "Nucleoplasm,Intermediate filaments,Cytosol" "Secreted to blood" NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA045946: AB_2679509, HPA075580: " "prognostic favorable (1.41e-4)" "unprognostic (1.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (1.32e-1)" "unprognostic (3.26e-1)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (6.92e-2)" "unprognostic (9.78e-3)" "unprognostic (6.51e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.03e-5)" "unprognostic (3.55e-1)" "unprognostic (3.62e-2)" "unprognostic (1.34e-2)" "unprognostic (1.49e-1)" 27.5 41.3 15.4 27.2 16.4 24.9 24.2 15.6 18.2 18.4 16.2 27.4 24.6 17.4 11.7 10.2 20.8 20.1 20.9 14.9 16.7 29.7 30.6 25.6 26.4 20.2 16.6 23.8 13.6 10.5 14.2 15.0 17.3 27.8 20.4 1.5 29.4 15.2 6.3 11.3 30.2 21.3 20.3 39.9 22.7 5.0 17.0 23.4 20.8 9.3 19.0 21.1 15.4 17.0 12.7 28.8 0.2 1.5 24.2 29.1 6.1 8.2 84.6 204.5 299.2 10.7 46.2 3.9 16.1 24.7 108.0 7.0 1.6 12.9 16.3 33.5 6.1 9.3 10.5 39.5 59.6 10.5 19.3 40.3 4.9 29.0 3.6 18.6 18.8 8.0 5.4 61.2 8.2 12.5 22.7 8.5 0.1 11.6 13.0 18.4 0.1 23.7 25.7 10.9 5.4 0.2 16.4 6.3 88.2 0.6 26.5 20.3 9.3 15.1 0.3 4.8 13.3 54.1 21.8 1.1 27.1 8.2 14.8 60.7 102.7 61.6 44.3 127.8 40.4 37.8 34.0 41.7 62.0 40.0 26.8 33.6 62.1 56.9 122.0 67.0 51.8 80.5 15.4 16.4 15.6 18.2 14.9 16.7 20.2 16.6 17.3 20.3 17.0 17.0 65.2 16.0 9.7 2.6 28.6 10.5 29.6 31.8 12.5 0.8 16.5 11.3 5.5 11.5 22.7 18.4 2.1 22.7 36.7 83.1 41.1 47.8 9.4 12.3 27.4 32.1 31.7 12.8 0.7 64.0 32.5 32.8 26.5 16.2 7.6 122.4 37.1 31.3 84.8 1.7 0.6 39.4 12.2 36.8 19.2 39.5 28.9 47.8 24.9 5.6 75.5 10.4 64.9 1.0 1.0 41.8 116.7 23.7 54.0 19.1 128.0 93.7 18.0 0.8 6.6 13.2 36.3 0.5 0.4 5.1 9.2 10.4 32.3 25.0 34.6 29.6 IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 673.8;Endothelial cells: 364.4;Leydig cells: 300.8;Sertoli cells: 276.1;T-cells: 595.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1494.7;gdT-cell: 2906.3;MAIT T-cell: 2003.4;memory CD4 T-cell: 3120.6;memory CD8 T-cell: 3000.3;naive CD4 T-cell: 2939.3;naive CD8 T-cell: 2996.4;neutrophil: 2741.6;NK-cell: 4679.9;T-reg: 1944.8" "Group enriched" "Detected in all" 7 "granulocytes: 2741.6;NK-cells: 4679.9;T-cells: 3120.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1038.8;BJ hTERT+ SV40 Large T+: 2266.3;BJ hTERT+ SV40 Large T+ RasG12V: 4016.8;HMC-1: 1138.9" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" 477.7 102.3 291.8 282.0 303.4 367.1 401.7 293.8 402.1 563.3 321.5 249.0 128.4 314.6 1152.4 147.4 537.4 247.9 368.4 292.6 305.4 317.5 191.4 246.5 417.2 324.8 295.6 607.5 78.8 154.0 145.1 278.5 322.5 190.6 172.0 14.9 199.8 324.3 134.2 164.6 252.4 367.4 308.6 679.7 141.6 56.3 317.5 296.5 263.4 259.3 295.9 307.4 364.7 304.3 125.7 5.5 1011.4 74.5 79.1 279.8 7.4 250.1 1038.8 2266.3 4016.8 3.7 782.2 3.0 157.9 257.1 23.5 269.0 36.5 26.2 52.0 255.3 51.8 125.9 77.5 11.8 668.2 182.8 1138.9 496.3 0.2 26.6 2.6 27.0 4.2 41.1 450.0 880.7 1.7 23.9 85.1 318.2 264.5 0.5 33.5 27.1 3.1 24.5 654.9 0.0 1.0 2.2 122.7 11.9 196.9 138.5 42.1 17.0 8.8 3.8 4.7 1.5 1.1 61.6 44.8 6.8 3.4 253.8 3.1 544.4 62.1 1494.7 2906.3 312.7 2003.4 364.9 3120.6 3000.3 114.2 323.6 2939.3 2996.4 2741.6 4679.9 539.0 33.7 1944.8 4673.8 291.8 303.4 293.8 402.1 292.6 305.4 324.8 295.6 322.5 308.6 317.5 304.3 240.7 35.3 119.4 2.6 88.2 27.9 17.1 70.2 673.8 0.0 13.0 12.6 8.4 2.8 115.3 33.1 0.0 3.3 258.6 13.7 5.9 1.7 1.4 14.6 96.5 364.4 1.2 27.8 0.0 1.4 30.7 236.0 33.6 20.8 18.9 5.6 164.6 24.6 11.8 0.0 0.0 17.3 10.2 10.1 26.8 3.8 300.8 45.4 78.2 42.2 2.1 0.0 126.7 0.0 0.2 0.7 15.0 124.5 141.2 2.3 15.0 1.0 26.0 0.0 276.1 16.4 213.4 0.6 1.5 50.4 14.3 4.0 595.8 2.1 29.2 5.7 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1675.3;Late spermatids: 2795.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 41.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035514, HPA035515" Supported Approved "Nuclear speckles,Mitochondria,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles" "Mitochondria, Cytosol" "HPA035514: AB_10601757, HPA035515: AB_10696505" "unprognostic (1.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (6.96e-5)" "unprognostic (2.98e-2)" "unprognostic (5.46e-3)" "unprognostic (1.02e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (3.59e-2)" "prognostic favorable (7.63e-4)" "unprognostic (5.04e-2)" "unprognostic (2.78e-1)" "unprognostic (1.68e-3)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (8.67e-3)" "unprognostic (6.12e-2)" 8.9 15.3 11.6 8.6 11.7 13.2 13.1 10.2 15.5 11.7 14.8 13.3 6.0 13.3 45.1 8.5 32.0 13.4 10.4 11.4 11.5 21.3 4.5 40.7 17.3 12.0 12.2 14.0 13.8 23.0 16.3 7.8 11.6 27.5 14.6 24.0 9.1 17.5 4.2 8.6 9.0 10.6 11.9 12.1 9.8 42.8 12.0 8.2 26.1 4.4 16.4 13.9 8.3 11.8 35.5 17.2 12.8 23.1 26.1 26.9 7.1 10.6 25.8 15.3 13.6 12.4 6.1 39.5 13.3 17.8 22.0 13.9 11.5 17.8 25.8 6.2 12.2 13.6 8.0 3.3 19.4 28.5 30.2 16.3 16.1 19.9 34.2 24.4 17.5 6.6 6.4 6.9 17.8 18.9 9.5 25.8 13.6 2.7 21.0 6.1 11.5 6.3 31.6 12.3 21.1 14.7 15.9 5.2 9.9 7.1 11.0 8.3 7.5 19.6 10.2 10.5 12.6 8.1 6.2 20.7 28.4 2.7 7.3 0.2 3.5 3.1 3.6 6.5 5.8 41.9 7.4 4.5 10.2 34.9 6.2 3.7 1.8 6.8 12.8 2.0 5.1 4.9 11.6 11.7 10.2 15.5 11.4 11.5 12.0 12.2 11.6 11.9 12.0 11.8 36.6 471.1 291.2 18.6 98.4 41.0 114.1 72.9 34.7 25.6 42.2 50.9 33.8 58.6 201.9 51.5 68.8 22.3 16.9 51.1 117.4 158.8 1675.3 266.3 57.8 38.2 57.2 13.7 52.6 134.1 19.3 78.9 25.5 37.0 44.3 57.1 25.7 5.9 14.5 28.6 20.3 35.7 42.7 8.1 27.7 2795.4 65.3 19.3 46.2 4.7 13.1 56.8 8.2 13.0 13.5 79.4 36.6 64.3 40.2 151.4 24.3 124.5 528.7 72.7 52.6 61.7 61.3 242.2 43.6 25.4 37.2 14.9 30.2 104.9 52.3 93.0 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.3;ovary: 16.2;retina: 50.6;testis: 35.7" "Cell type enhanced" "Detected in many" "Astrocytes: 133.9;Early spermatids: 257.9;Inhibitory neurons: 139.1;Late spermatids: 334.0;Oligodendrocytes: 283.2" "Group enriched" "Detected in many" 9 "glioma: 9.2;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 8.0;HEL: 5.9;SK-MEL-30: 35.1;U-266/70: 11.9;U-266/84: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: AB_10966195" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-3)" "unprognostic (2.51e-2)" "unprognostic (3.56e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (8.70e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-4)" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (7.57e-2)" 0.3 7.8 19.5 0.4 34.0 0.0 0.2 26.9 22.2 0.8 1.5 4.1 0.2 0.5 1.1 1.2 0.6 0.8 2.2 19.3 18.6 8.2 0.1 0.1 0.1 30.5 28.0 16.2 3.7 1.3 1.7 0.1 29.9 0.7 0.8 50.6 0.6 0.8 3.9 1.5 0.9 0.5 23.3 0.1 1.6 35.7 25.6 0.3 3.4 5.0 0.2 0.6 0.8 46.3 0.0 8.0 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 2.7 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.7 0.6 0.0 0.1 35.1 2.1 0.7 0.1 0.0 0.0 1.4 0.0 0.1 11.9 15.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 34.0 26.9 22.2 19.3 18.6 30.5 28.0 29.9 23.3 25.6 46.3 0.1 0.0 0.0 133.9 0.6 0.4 0.1 0.3 2.8 9.1 0.3 0.1 1.3 0.0 0.5 0.0 75.0 0.2 0.1 0.0 0.0 0.9 257.9 4.2 0.8 0.3 0.0 0.0 77.8 0.7 0.0 2.0 0.0 7.2 0.0 26.8 0.0 0.0 0.0 16.8 139.1 0.0 6.1 0.0 0.4 334.0 3.7 0.4 3.6 4.7 0.0 22.3 0.0 43.2 283.2 0.2 0.0 1.9 0.2 0.1 0.0 5.9 0.4 25.7 0.0 0.8 0.9 22.4 6.0 0.7 0.0 0.1 0.2 6.8 0.0 0.4 IKZF2 "Helios, ZNFN1A2" ENSG00000030419 "IKAROS family zinc finger 2" Q9UKS7 2 212999691-213152427 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 77.4;Oligodendrocyte precursor cells: 100.5;Oligodendrocytes: 78.3;Squamous epithelial cells: 47.8;Urothelial cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 4.8;NK-cells: 5.5;T-cells: 5.8" "Cell line enhanced" "Detected in many" "JURKAT: 70.5;MOLT-4: 31.1;RT4: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059142 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA059142: AB_2683923" "unprognostic (2.29e-1)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (3.03e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.21e-1)" "unprognostic (3.56e-3)" "unprognostic (4.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.93e-3)" "unprognostic (7.09e-2)" 2.1 2.0 2.6 3.8 5.5 5.5 2.3 3.2 3.2 3.4 0.7 1.8 0.8 1.9 3.2 19.4 2.8 3.1 1.9 2.9 3.8 1.5 1.4 2.9 7.0 5.2 3.5 2.0 2.0 5.2 1.9 2.0 5.3 3.3 1.7 5.5 8.4 4.3 4.1 9.1 1.2 0.8 3.2 5.5 4.4 2.5 3.9 40.3 7.8 1.6 6.8 9.6 8.3 7.4 2.8 1.0 5.3 0.3 17.1 17.2 3.3 3.4 3.9 0.8 1.7 1.4 4.6 3.7 4.4 2.0 0.4 6.5 0.1 1.8 2.7 0.0 0.9 1.9 3.6 0.5 0.1 8.9 0.6 16.9 1.6 0.1 0.5 4.3 0.0 70.5 1.2 3.1 1.6 5.2 31.1 8.9 1.1 2.2 0.8 18.1 3.5 0.0 1.5 28.6 1.6 1.0 0.0 3.6 0.0 4.4 4.8 0.9 9.2 4.9 3.8 2.3 0.7 6.0 2.0 20.6 2.4 0.0 1.1 3.9 0.0 4.8 1.8 0.0 4.9 0.2 0.6 1.4 0.0 1.0 0.3 1.5 0.0 5.5 0.0 0.5 5.8 0.3 2.6 5.5 3.2 3.2 2.9 3.8 5.2 3.5 5.3 3.2 3.9 7.4 2.1 9.6 12.6 77.4 5.2 5.9 23.2 7.9 11.4 4.8 5.1 2.2 7.6 1.5 19.5 7.3 4.2 4.3 27.4 2.8 0.0 2.3 1.3 16.1 1.8 2.4 3.0 9.0 17.7 3.1 1.2 2.7 8.6 18.1 3.8 2.5 2.5 2.2 2.1 0.0 19.9 2.3 4.1 2.4 2.1 0.7 1.8 2.8 1.8 31.9 1.3 3.0 39.1 100.5 78.3 3.6 1.0 2.2 13.9 15.9 1.1 1.0 31.7 7.3 0.0 10.2 4.5 0.8 0.7 47.8 8.7 4.0 22.1 2.0 1.4 51.8 IKZF5 "FLJ22973, Pegasus, ZNFN1A5" ENSG00000095574 "IKAROS family zinc finger 5" Q9H5V7 10 122990807-123008812 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015297, HPA051574" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA015297: AB_1855183, HPA051574: AB_2681538" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.64e-2)" "unprognostic (2.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.66e-3)" "unprognostic (2.68e-1)" "unprognostic (9.14e-3)" "unprognostic (5.43e-2)" "unprognostic (2.99e-1)" "unprognostic (6.88e-2)" "unprognostic (1.63e-2)" "unprognostic (3.98e-3)" "unprognostic (4.17e-2)" "unprognostic (6.03e-2)" "unprognostic (6.96e-2)" "unprognostic (3.15e-2)" 8.3 8.5 8.7 7.3 11.5 34.0 12.2 10.2 15.1 8.8 5.9 7.6 6.6 9.3 9.7 7.2 8.4 6.1 7.1 8.3 10.3 8.7 12.2 8.2 11.1 10.4 10.4 13.9 11.1 9.3 10.1 8.1 11.2 8.3 7.1 13.6 8.4 6.0 9.7 11.3 8.5 7.1 10.0 9.2 7.9 10.5 9.8 10.5 10.0 9.4 9.6 7.3 8.4 17.7 7.5 3.7 7.3 12.5 11.5 10.5 7.9 6.2 13.3 8.1 9.8 6.0 8.6 18.8 4.5 7.6 4.4 10.1 13.0 9.3 11.9 10.6 11.5 12.1 6.0 9.0 7.6 14.8 10.6 8.3 12.5 9.7 20.8 11.1 9.0 12.3 16.9 12.2 8.8 5.5 13.6 16.1 6.7 5.6 5.1 10.9 9.1 10.8 6.7 5.1 7.9 7.1 5.1 6.3 12.2 5.8 5.2 9.3 9.3 5.8 4.9 8.6 10.1 11.4 6.6 17.6 7.4 25.5 3.5 6.0 4.1 5.7 5.8 5.3 6.8 4.0 5.3 5.7 4.5 4.7 7.2 8.4 4.0 6.7 5.6 3.1 7.5 4.3 8.7 11.5 10.2 15.1 8.3 10.3 10.4 10.4 11.2 10.0 9.8 17.7 11.2 12.8 13.1 8.8 16.0 32.2 11.0 7.2 20.5 12.7 23.8 15.0 15.6 8.6 11.3 5.5 14.6 5.8 20.5 7.7 9.8 5.1 8.6 12.0 13.2 11.5 18.0 12.4 10.9 5.3 5.7 15.6 7.7 20.7 17.1 11.3 9.7 15.7 6.5 11.8 13.0 9.2 4.1 10.6 11.4 3.7 13.4 11.0 16.0 17.8 8.9 9.0 17.5 13.0 30.9 4.7 4.9 10.5 14.2 16.1 7.4 11.4 10.9 14.1 13.1 14.3 11.6 22.8 22.3 20.4 32.4 14.4 19.3 7.0 6.7 11.9 IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.0;testis: 30.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 322.4" "Cancer enhanced" "Detected in many" "glioma: 17.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 133.0;U-2197: 425.6;U-251 MG: 297.4;U-87 MG: 167.9" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in some" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.97e-1)" "unprognostic (2.83e-1)" "unprognostic (6.62e-4)" "unprognostic (7.39e-2)" "unprognostic (8.45e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.55e-4)" "unprognostic (3.54e-1)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (1.53e-5)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.70e-3)" "unprognostic (1.20e-1)" 0.8 4.8 1.3 4.0 1.9 0.0 0.4 0.1 1.1 1.1 1.6 0.4 0.3 0.8 4.4 0.6 0.1 0.8 0.7 1.5 10.6 3.6 10.0 1.4 0.1 3.1 3.7 0.1 0.1 0.5 12.0 0.4 1.8 4.1 0.7 0.0 0.9 3.5 0.0 0.2 0.3 0.3 0.7 0.2 0.1 30.0 6.1 2.1 1.2 0.1 0.1 4.4 0.2 0.8 0.4 0.0 4.6 0.1 0.7 3.6 0.0 29.2 28.0 0.1 0.1 0.0 0.0 0.0 0.5 14.6 46.6 0.1 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.1 4.8 0.8 4.6 26.9 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 133.0 0.0 0.0 0.0 2.4 0.2 0.0 6.8 2.1 0.3 0.4 0.0 0.1 0.4 0.0 14.7 0.4 425.6 297.4 0.0 0.2 0.1 167.9 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.9 0.1 1.1 1.5 10.6 3.1 3.7 1.8 0.7 6.1 0.8 0.3 0.0 0.0 0.0 0.1 0.1 4.7 0.3 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 322.4 0.4 0.3 1.3 4.2 0.0 0.4 0.0 0.0 10.3 0.0 0.4 0.0 0.0 46.4 0.4 0.0 0.0 0.6 0.0 0.0 2.8 0.3 58.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 8.5 0.0 4.9 0.1 10.9 0.0 0.0 2.9 0.0 0.0 0.0 3.4 63.1 4.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.5;skin 1: 149.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Basal respiratory cells: 186.4;Basal squamous epithelial cells: 215.1;Kupffer cells: 241.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 117.9;CAPAN-2: 182.3;HaCaT: 167.0;HBEC3-KT: 125.8;hTCEpi: 188.5;PC-3: 110.2;U-2 OS: 208.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA Yes 196000 16000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: AB_562304, HPA003980: AB_1851670" "unprognostic (2.31e-3)" "unprognostic (3.25e-1)" "prognostic favorable (2.78e-4)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (8.15e-2)" "unprognostic (3.23e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-3)" "unprognostic (4.13e-1)" "unprognostic (3.58e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (9.01e-2)" 19.9 6.1 5.3 18.2 5.4 31.6 12.6 5.9 8.6 38.0 7.0 34.1 22.0 2.4 3.3 124.5 8.0 23.0 3.0 5.3 6.0 23.8 9.1 23.0 67.8 7.5 6.2 1.9 17.9 1.3 2.9 6.7 7.4 6.1 29.1 6.9 15.0 3.0 6.0 149.6 22.0 3.6 6.7 29.3 13.4 1.9 5.7 8.0 3.7 2.1 25.7 25.3 77.0 11.3 117.9 40.0 0.0 0.4 0.0 0.0 0.7 2.0 0.0 0.0 0.1 22.4 182.3 0.1 25.7 0.3 3.2 167.0 0.0 125.8 0.0 0.3 1.2 17.5 35.6 9.9 3.9 9.3 32.6 0.2 188.5 0.3 43.5 0.2 0.1 0.1 0.5 0.3 1.6 0.2 0.2 0.9 0.2 31.9 110.2 0.1 0.1 0.4 79.9 24.8 0.1 0.0 78.4 52.1 0.5 1.0 31.0 25.4 0.3 0.4 208.9 1.2 35.9 0.4 0.3 0.6 0.2 67.1 0.2 6.8 8.7 16.0 0.1 10.9 0.0 0.7 0.1 0.0 25.8 0.7 0.0 0.5 9.5 19.6 6.3 5.6 0.0 2.5 5.3 5.4 5.9 8.6 5.3 6.0 7.5 6.2 7.4 6.7 5.7 11.3 1.0 173.1 38.4 0.7 6.0 122.9 33.5 186.4 215.1 2.6 4.6 7.7 1.0 41.5 66.1 9.2 0.0 2.3 10.8 109.9 80.3 24.7 2.4 94.9 1.4 4.6 14.5 26.3 3.8 143.0 3.7 18.8 20.9 32.5 101.2 2.8 8.2 1.9 68.4 0.0 4.6 30.1 57.0 241.0 37.3 1.9 0.0 123.8 3.6 61.8 38.8 2.7 6.2 2.0 1.1 161.4 104.6 4.5 4.6 23.6 67.5 22.3 69.6 39.1 6.6 0.6 3.9 1.5 1.3 152.6 111.2 1.8 9.6 0.3 47.8 90.5 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 14.3;lymphoid tissue: 39.4;skin 1: 31.3" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 136.0;Club cells: 36.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;HaCaT: 1.0" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.9 0.2 0.0 31.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 39.4 0.8 3.6 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 136.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 1.3 0.2 0.0 1.7 13.2 0.0 0.0 0.0 0.0 7.8 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 ILF3 "DRBP76, MPHOSPH4, MPP4, MPP4110, NF110, NF110b, NF90, NF90a, NF90c, NF90ctv, NFAR-1, NFAR-2, NFAR110, NFAR90, TCP110" ENSG00000129351 "Interleukin enhancer binding factor 3" Q12906 19 10654261-10692417 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001897 Supported Enhanced Nucleoplasm,Nucleoli,Mitochondria No No 1600000 "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Mitochondria" "HPA001897: AB_1078703" "unprognostic (2.39e-1)" "unprognostic (9.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (5.55e-3)" "unprognostic (1.11e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.45e-2)" "unprognostic (1.04e-1)" "unprognostic (4.38e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (7.57e-3)" "unprognostic (7.61e-2)" "unprognostic (1.03e-1)" "unprognostic (6.20e-2)" 49.2 58.5 31.6 79.4 31.5 179.5 49.8 44.2 37.5 60.8 38.5 56.0 52.0 64.5 40.9 60.4 61.1 31.9 49.0 31.4 37.9 43.1 32.1 50.5 82.9 30.6 32.8 76.5 52.6 55.5 53.8 47.8 29.7 52.4 44.8 69.5 54.0 48.8 83.6 58.7 56.1 49.8 29.4 61.7 47.8 78.9 35.4 97.3 61.6 58.2 72.3 56.1 52.1 42.8 285.9 226.7 359.5 330.9 76.5 104.0 208.9 178.1 149.6 291.8 226.5 261.8 160.8 353.2 172.1 160.8 178.0 248.9 392.5 240.7 260.9 227.2 349.5 459.3 206.9 247.5 109.2 334.8 219.5 99.0 105.0 232.1 257.4 111.1 253.1 201.7 400.0 269.4 172.3 233.8 558.1 534.0 433.3 149.2 246.2 405.2 342.2 244.2 116.3 297.1 395.1 286.7 229.0 179.4 131.6 161.6 152.2 212.0 205.2 237.6 224.2 249.3 356.5 228.9 339.7 431.4 132.8 351.6 262.2 20.2 18.1 10.2 24.4 14.1 20.6 19.3 20.2 22.3 22.8 22.9 19.5 20.2 2.7 21.3 21.2 25.1 20.6 11.8 31.6 31.5 44.2 37.5 31.4 37.9 30.6 32.8 29.7 29.4 35.4 42.8 63.6 99.3 133.9 34.3 106.2 86.2 110.0 64.2 104.7 95.4 77.5 64.3 69.7 60.1 98.8 42.3 85.5 90.0 100.0 78.4 27.4 89.0 21.2 89.8 105.7 77.4 114.0 124.3 24.4 80.4 111.1 94.8 101.9 121.4 96.8 145.9 36.8 47.9 71.4 94.2 34.0 85.6 50.8 55.0 68.3 21.0 76.4 75.8 39.2 24.4 66.0 69.2 92.7 31.7 28.9 88.2 55.6 62.4 124.9 144.6 38.8 47.2 82.9 103.6 32.9 100.3 80.1 137.2 120.6 113.8 77.0 70.9 103.5 140.8 111.7 94.9 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 ILRUN "C6orf106, dJ391O22.4, FLJ22195" ENSG00000196821 "Inflammation and lipid regulator with UBA-like and NBR1-like domains" Q9H6K1 6 34587288-34696859 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 211.7" "Cell type enhanced" "Detected in some" "Adipocytes: 9.9;Cardiomyocytes: 73.7;Cytotrophoblasts: 13.7;dendritic cells: 11.8;Hofbauer cells: 15.6;Syncytiotrophoblasts: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034489, HPA034490" Approved Supported "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Centrosome, Cytosol" "HPA034489: AB_10669991, HPA034490: AB_2674186" "unprognostic (3.76e-2)" "unprognostic (2.51e-1)" "unprognostic (7.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (8.40e-2)" "unprognostic (9.94e-2)" "unprognostic (7.57e-2)" "unprognostic (5.68e-2)" "unprognostic (3.55e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" 57.0 35.3 38.4 31.4 39.3 28.6 35.2 48.8 51.6 26.6 36.2 43.4 30.1 29.5 29.0 42.1 27.2 29.3 76.8 39.8 39.8 43.1 77.1 42.5 34.0 41.6 49.9 25.8 30.3 47.3 24.5 30.4 41.5 30.7 29.8 46.7 33.9 32.4 211.7 37.0 35.7 39.4 39.6 31.6 35.0 67.8 43.7 32.9 37.4 187.4 44.8 40.2 28.1 41.4 94.0 41.8 40.3 59.8 95.7 51.9 48.5 63.5 72.3 72.1 89.4 83.0 42.1 107.0 46.1 62.3 99.5 90.7 120.0 52.6 90.3 151.4 47.0 89.2 47.3 80.0 93.4 76.0 96.2 35.4 108.0 73.3 66.4 49.5 58.6 43.9 103.0 43.6 41.7 56.3 52.7 52.7 37.7 152.0 37.3 40.6 52.2 57.0 57.0 91.2 48.6 38.0 93.3 44.9 91.8 82.1 56.5 63.3 60.1 59.1 45.6 63.0 62.7 63.2 154.3 81.8 21.3 66.7 70.1 23.9 3.7 8.1 8.9 6.6 4.7 6.7 6.4 7.1 4.4 8.1 3.5 5.5 4.6 6.2 8.3 2.2 10.0 5.7 38.4 39.3 48.8 51.6 39.8 39.8 41.6 49.9 41.5 39.6 43.7 41.4 9.9 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.0 0.0 0.0 0.0 13.7 11.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 8.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 21.6 1.6 0.0 0.0 0.0 INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" 3.1 2.5 2.7 7.5 1.1 20.9 2.8 6.2 3.0 4.6 0.0 4.8 6.8 3.0 8.1 14.0 3.5 2.2 2.8 2.9 0.5 2.4 1.9 3.0 11.6 1.6 0.8 3.8 3.1 3.1 1.5 4.1 1.3 2.5 3.6 3.4 6.1 2.9 4.2 7.9 5.7 3.4 0.1 5.5 4.5 6.4 0.5 17.8 5.1 3.4 8.2 2.8 5.5 1.2 74.3 69.4 51.6 45.5 6.8 8.4 28.1 47.6 21.2 44.4 28.3 37.0 50.7 70.0 36.2 16.0 46.2 72.6 52.2 28.4 31.8 60.5 36.6 45.7 68.0 29.6 2.7 53.5 62.1 4.3 6.5 41.3 23.6 6.8 25.8 50.2 48.8 57.6 25.3 59.7 85.0 43.3 56.2 28.0 34.4 79.3 66.4 53.4 12.0 35.8 40.1 42.2 46.8 30.8 27.9 19.8 48.2 19.4 28.5 41.8 51.9 59.8 50.0 29.7 48.3 75.8 23.5 34.7 50.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.7 1.1 6.2 3.0 2.9 0.5 1.6 0.8 1.3 0.1 0.5 1.2 1.2 3.2 2.3 1.3 3.4 5.6 0.8 1.0 2.8 2.4 1.1 0.6 1.3 0.0 3.7 0.0 0.0 4.2 4.2 5.4 0.0 1.9 1.0 2.0 2.1 1.5 0.0 10.9 3.3 2.5 7.1 1.9 9.2 2.7 3.8 5.7 0.0 0.7 4.2 0.0 2.5 3.4 0.0 0.9 1.6 0.5 2.8 3.3 3.6 1.0 5.0 1.5 3.1 2.0 1.5 2.2 1.6 1.5 10.9 1.2 1.3 0.3 2.6 2.3 0.0 1.9 4.3 6.5 7.8 15.1 3.3 2.2 3.7 1.9 4.8 1.1 INKA2 "C1orf183, FAM212B, FLJ31105" ENSG00000197852 "Inka box actin regulator 2" Q9NTI7 1 111680630-111755824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "Hofbauer cells: 4.0" "Cancer enhanced" "Detected in many" "glioma: 6.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 13 "neutrophil: 25.2" "Lineage enriched" "Detected in many" 13 "granulocytes: 25.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 35.6;U-87 MG: 73.0;WM-115: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027809, HPA027810, HPA027811" Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 47: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Vesicles" "HPA027809: AB_10599616, HPA027810: , HPA027811: AB_10600872" "unprognostic (1.92e-1)" "unprognostic (9.70e-3)" "unprognostic (1.84e-1)" "unprognostic (1.85e-2)" "unprognostic (2.81e-2)" "prognostic favorable (4.51e-5)" "unprognostic (9.96e-4)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (9.50e-3)" "unprognostic (9.92e-5)" "unprognostic (8.66e-2)" "unprognostic (1.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-3)" "unprognostic (5.07e-2)" 7.4 1.0 8.8 3.0 13.0 2.9 4.0 5.0 16.7 2.3 2.0 3.5 1.2 3.9 1.7 6.6 5.1 2.9 13.8 14.6 4.0 2.7 0.9 4.8 1.0 4.3 3.8 2.1 1.2 2.3 0.7 6.1 3.9 3.0 2.4 1.4 2.3 4.0 7.8 5.5 2.4 5.8 3.5 5.3 3.8 2.6 4.0 2.1 2.5 8.9 1.7 2.8 3.4 9.8 2.5 2.3 5.1 3.2 20.5 7.3 1.7 1.8 4.0 3.3 7.8 4.1 0.1 2.0 0.9 1.8 1.6 2.2 2.2 4.9 3.2 4.6 1.9 15.0 1.8 4.0 8.1 1.1 2.3 6.0 20.9 35.6 1.6 0.9 8.9 2.6 0.1 3.3 5.3 2.8 1.1 1.2 1.2 2.4 2.0 2.2 19.4 0.7 0.9 3.5 10.2 3.4 1.1 0.1 9.8 5.6 2.8 3.3 3.5 7.1 11.4 3.9 1.5 20.7 3.8 2.1 73.0 4.5 28.0 0.2 1.8 1.4 0.0 1.4 0.0 0.2 0.1 0.1 1.0 0.4 0.0 0.0 25.2 0.6 2.0 0.5 0.0 0.6 8.8 13.0 5.0 16.7 14.6 4.0 4.3 3.8 3.9 3.5 4.0 9.8 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 INO80 "hINO80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex ATPase subunit" Q9ULG1 15 40978880-41116280 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041484, HPA048601" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" Cytosol "HPA041484: AB_2677506, HPA048601: " "unprognostic (5.39e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.93e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "prognostic favorable (6.30e-4)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-2)" 9.3 6.5 5.4 7.3 5.7 15.7 8.8 10.1 5.9 8.3 5.3 9.3 7.3 8.9 4.7 9.6 7.7 5.7 6.9 5.3 5.2 7.9 7.8 9.4 9.7 5.9 5.2 9.1 6.9 10.0 5.5 6.8 5.6 7.9 8.6 5.7 7.3 6.6 15.7 10.9 8.7 8.2 5.0 8.9 7.9 7.0 5.8 10.8 8.5 9.6 10.4 9.1 8.5 7.5 13.1 12.9 10.6 10.7 16.5 13.8 11.4 12.2 18.8 17.3 15.0 14.8 10.4 14.0 8.8 17.6 21.6 24.3 19.5 20.7 19.0 17.5 10.0 18.9 17.7 11.8 15.2 17.9 16.2 13.5 18.4 13.8 36.9 11.1 16.8 14.5 20.5 11.6 12.3 10.6 13.2 11.2 11.3 20.6 13.5 19.1 11.2 11.0 12.7 26.1 14.5 9.6 9.6 18.5 7.3 10.4 10.5 19.9 19.2 14.3 11.1 17.3 19.0 12.4 9.6 22.2 16.1 24.7 11.7 0.3 1.0 0.2 0.8 0.5 0.9 1.3 0.8 0.8 0.7 1.1 1.0 1.1 0.3 2.1 0.2 0.6 0.7 0.4 5.4 5.7 10.1 5.9 5.3 5.2 5.9 5.2 5.6 5.0 5.8 7.5 23.7 9.6 25.7 27.4 27.6 8.5 16.2 7.5 23.3 30.4 18.1 15.9 25.1 14.3 16.4 16.5 22.9 13.5 25.4 17.3 7.9 17.6 2.2 17.2 21.5 17.6 13.1 23.8 54.1 13.3 12.0 16.0 32.6 28.9 15.8 18.4 13.2 10.0 9.8 26.9 47.5 11.8 2.0 14.4 6.8 3.3 14.6 18.6 7.2 25.3 20.8 12.9 19.6 43.2 53.3 15.2 16.1 15.8 19.8 21.7 9.5 11.3 16.3 33.0 6.6 28.1 21.3 19.2 24.7 28.2 12.8 19.2 25.8 25.1 13.9 15.1 INO80B "hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4" ENSG00000115274 "INO80 complex subunit B" Q9C086 2 74455087-74457944 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 28.0;Suprabasal keratinocytes: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA070644, HPA078274" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Nucleoli, Nuclear bodies" "HPA070644: AB_2732159, HPA078274: " "prognostic favorable (2.89e-4)" "unprognostic (2.24e-2)" "unprognostic (5.62e-2)" "unprognostic (6.59e-3)" "unprognostic (9.45e-2)" "unprognostic (3.82e-2)" "unprognostic (2.20e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-2)" "unprognostic (7.52e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (1.56e-5)" "prognostic favorable (8.44e-4)" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (1.18e-3)" 26.3 30.5 18.9 18.0 20.7 20.6 29.1 17.2 27.6 38.1 15.7 24.1 19.4 30.4 17.1 31.1 31.5 15.1 20.1 19.6 17.5 27.4 32.1 25.9 18.9 18.4 17.1 48.1 41.9 19.6 42.0 11.6 19.2 34.7 12.3 18.7 29.9 17.9 30.1 40.8 23.9 14.8 14.2 24.5 32.7 31.0 16.7 12.8 39.3 9.1 20.1 27.1 32.2 20.9 27.8 29.0 11.0 14.2 21.0 29.6 28.2 25.7 23.0 19.4 16.3 19.9 34.4 46.7 32.2 18.8 18.2 29.1 9.1 20.4 15.8 42.5 28.8 35.9 14.5 20.5 22.4 33.9 17.2 29.5 35.0 27.8 31.2 48.4 26.2 27.4 20.7 18.5 16.5 32.7 44.3 47.7 7.7 20.2 39.7 26.3 34.9 47.4 23.5 18.9 16.7 31.8 13.5 37.3 15.4 12.1 16.1 11.6 22.1 17.7 27.9 29.7 20.0 65.8 48.4 16.9 33.3 21.3 18.9 3.2 2.5 1.0 1.2 1.9 1.6 2.6 1.4 0.7 1.6 2.1 1.2 1.1 3.2 2.1 1.7 3.2 2.2 0.9 18.9 20.7 17.2 27.6 19.6 17.5 18.4 17.1 19.2 14.2 16.7 20.9 4.4 0.0 2.2 0.0 5.4 28.0 2.8 8.5 2.2 14.0 11.3 6.0 0.9 4.3 6.8 3.7 12.5 4.3 7.1 5.8 0.0 15.9 3.0 6.5 5.7 5.4 4.8 9.3 0.0 27.0 4.7 3.4 2.6 3.8 5.7 2.4 6.8 10.8 5.6 13.5 0.0 7.9 12.2 9.7 21.0 6.5 3.1 4.3 5.4 0.0 12.5 4.7 9.2 0.0 0.0 17.4 3.3 3.0 5.1 2.2 11.6 6.5 12.3 15.0 0.0 2.1 4.9 5.6 1.9 3.3 31.7 5.3 7.5 2.2 6.7 2.0 INTS12 "INT12, PHF22, SBBI22" ENSG00000138785 "Integrator complex subunit 12" Q96CB8 4 105682627-105895986 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035772, HPA041814" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA035772: AB_10671109, HPA041814: AB_2677687" "unprognostic (5.30e-2)" "unprognostic (4.54e-2)" "unprognostic (1.84e-3)" "unprognostic (1.78e-1)" "unprognostic (3.68e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.95e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-3)" "unprognostic (3.00e-2)" "unprognostic (3.48e-2)" "unprognostic (5.93e-3)" "unprognostic (3.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-1)" 15.2 11.1 12.8 10.9 13.3 30.4 20.2 14.9 18.0 14.1 12.0 14.7 18.1 14.6 17.8 13.5 13.2 12.7 18.9 12.4 14.9 18.7 22.6 16.4 14.0 12.3 14.0 11.6 12.6 17.2 10.3 11.9 12.5 18.1 15.6 17.2 14.4 13.4 26.5 14.0 15.5 17.1 12.7 12.6 15.0 13.9 14.3 19.9 19.9 26.0 17.0 15.6 11.2 13.7 24.4 12.8 28.5 29.8 27.5 32.6 20.8 28.2 29.1 34.7 35.9 18.1 26.9 34.9 15.4 31.9 26.9 13.8 31.7 40.7 42.8 36.9 19.0 26.3 19.6 25.7 44.3 46.7 23.0 31.0 51.7 34.5 51.4 22.5 32.3 29.1 39.8 26.7 37.8 25.6 55.3 28.9 12.4 35.3 19.5 28.0 31.0 26.8 32.5 16.3 30.7 24.6 19.8 32.6 31.0 22.4 26.4 27.2 21.3 22.7 23.3 24.8 30.5 40.8 40.9 52.2 25.3 31.5 46.0 64.0 23.7 38.5 25.7 26.6 28.9 33.0 29.4 29.4 27.7 32.1 30.6 28.3 17.9 42.9 28.3 42.6 34.8 21.9 12.8 13.3 14.9 18.0 12.4 14.9 12.3 14.0 12.5 12.7 14.3 13.7 19.0 12.8 11.8 14.0 15.1 11.0 11.8 25.8 15.4 10.5 12.1 11.7 18.7 11.5 12.9 3.7 10.4 16.1 13.6 8.3 43.0 25.2 35.8 8.1 11.2 16.8 6.0 15.6 13.8 20.3 18.6 10.8 8.6 8.7 24.7 9.9 11.7 9.3 17.8 10.1 15.7 5.2 30.5 9.0 9.5 28.4 12.2 9.8 7.2 9.4 15.5 14.0 21.6 27.2 19.1 20.5 6.8 8.2 18.9 14.2 16.5 17.1 6.2 9.3 0.0 12.9 20.1 13.4 16.2 14.1 10.4 18.3 13.0 14.9 10.2 11.0 INTS13 "ASUN, C12orf11, FLJ10637, Mat89Bb, NET48, SPATA30" ENSG00000064102 "Integrator complex subunit 13" Q9NVM9 12 26905181-26938326 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Endometrial stromal cells: 16.7;Extravillous trophoblasts: 16.1;Theca cells: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039543, HPA040109, HPA073020" Uncertain Enhanced "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Vesicles" "HPA039543: AB_10795150, HPA040109: , HPA073020: " "unprognostic (2.09e-1)" "unprognostic (8.48e-3)" "unprognostic (2.75e-2)" "unprognostic (1.40e-3)" "unprognostic (3.94e-2)" "unprognostic (3.01e-2)" "prognostic unfavorable (1.17e-10)" "unprognostic (5.22e-3)" "unprognostic (5.28e-2)" "unprognostic (1.67e-2)" "unprognostic (1.78e-3)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.16e-6)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (4.37e-2)" "unprognostic (4.78e-2)" 9.9 21.4 9.3 11.3 13.4 17.2 11.7 13.2 14.3 10.4 8.1 9.7 9.9 10.0 10.3 14.6 8.5 8.2 12.2 9.5 11.6 13.2 15.1 7.9 16.7 15.4 12.0 8.0 11.5 8.0 8.1 10.0 14.8 8.5 10.7 21.8 9.0 7.0 19.0 11.8 8.5 11.9 13.9 12.9 15.4 12.1 12.2 18.6 9.9 18.1 16.8 12.8 10.6 20.0 33.4 38.1 21.5 46.4 30.5 48.9 30.9 44.9 27.4 43.3 48.1 58.4 43.1 82.7 45.0 25.1 40.6 46.2 56.1 43.6 72.8 39.5 37.4 66.7 44.5 44.9 53.9 110.6 38.4 26.3 32.2 69.5 147.0 53.5 56.8 35.6 71.5 31.9 46.7 40.9 57.9 197.8 94.6 45.6 68.9 40.8 62.3 114.0 36.4 31.0 17.8 16.7 39.1 30.6 47.4 72.8 42.6 23.4 36.5 50.1 36.2 85.6 55.1 15.6 19.6 119.4 33.1 75.8 36.2 7.8 8.1 7.8 14.6 5.7 22.1 9.7 18.2 18.2 9.9 11.3 12.7 15.7 2.5 25.9 5.2 6.7 28.1 10.5 9.3 13.4 13.2 14.3 9.5 11.6 15.4 12.0 14.8 13.9 12.2 20.0 7.2 22.4 7.8 0.0 2.7 0.0 0.0 0.0 0.0 0.0 7.9 8.3 0.0 0.0 2.5 5.5 0.0 11.8 8.8 0.0 3.9 13.7 0.0 8.7 16.7 3.9 0.0 0.0 0.0 11.9 16.1 8.3 0.0 8.2 7.6 13.9 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 5.7 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.6 0.0 0.0 11.6 2.9 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 13.1 6.5 18.5 0.0 0.0 INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Extravillous trophoblasts: 30.5;Syncytiotrophoblasts: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: AB_10805710, HPA040651: AB_10796559" "unprognostic (2.92e-1)" "unprognostic (3.01e-1)" "unprognostic (2.78e-1)" "unprognostic (2.41e-1)" "unprognostic (4.06e-1)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (5.60e-2)" "unprognostic (2.57e-2)" "unprognostic (2.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.92e-2)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (1.30e-1)" 12.5 15.8 13.2 14.2 15.8 18.0 22.3 14.7 16.6 20.9 18.2 21.8 14.1 18.1 27.4 16.1 24.2 19.6 13.4 13.5 14.8 21.3 21.1 15.6 22.7 14.5 14.9 18.4 17.7 22.9 16.3 19.2 14.6 19.1 23.6 13.1 16.2 19.8 9.9 18.0 17.2 18.8 14.8 18.9 18.1 18.9 15.8 25.4 23.2 13.6 24.3 23.6 13.6 17.7 26.4 46.7 46.1 36.8 25.2 31.4 29.5 28.4 36.5 46.4 42.5 42.2 61.2 42.9 38.9 35.6 38.5 52.0 99.4 47.6 40.5 37.8 60.2 37.5 32.2 46.4 50.0 38.7 46.2 30.6 46.9 35.1 53.7 34.1 50.8 64.8 52.2 24.3 33.4 41.7 44.3 41.2 33.8 66.2 25.6 37.5 38.8 49.0 36.7 48.6 33.1 26.3 34.2 34.5 49.5 39.2 32.3 44.0 25.2 31.8 33.2 28.8 45.6 23.9 48.4 58.1 32.1 70.0 38.1 25.7 11.0 6.2 19.8 12.7 22.3 19.3 20.3 22.6 19.8 14.8 21.1 19.2 1.2 23.8 9.5 17.9 30.8 16.6 13.2 15.8 14.7 16.6 13.5 14.8 14.5 14.9 14.6 14.8 15.8 17.7 12.2 22.4 10.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 13.0 11.0 0.0 0.0 5.6 12.9 0.0 40.5 7.7 0.0 21.5 18.2 0.0 12.8 11.8 6.8 0.0 0.0 0.0 15.4 30.5 6.7 0.0 12.6 7.6 22.5 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 9.3 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.5 0.0 0.0 15.1 10.9 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 49.8 4.8 24.0 0.0 0.0 INTS6L "DDX26B, FLJ41215" ENSG00000165359 "Integrator complex subunit 6 like" Q5JSJ4 X 135520659-135582510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Breast myoepithelial cells: 14.0;dendritic cells: 15.9;Endometrial ciliated cells: 16.0;Glandular and luminal cells: 11.1;granulocytes: 25.2;Theca cells: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 20.7;U-937: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001552, HPA013200, HPA013335, HPA030747" Uncertain Approved "Nuclear bodies,Centrosome,Mitochondria" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Centrosome "Nuclear bodies, Mitochondria" "HPA001552: AB_1078659, HPA013200: AB_2668801, HPA013335: AB_1847553, HPA030747: AB_2673589" "unprognostic (2.03e-1)" "prognostic favorable (5.39e-4)" "unprognostic (1.96e-1)" "unprognostic (7.42e-2)" "unprognostic (2.89e-2)" "unprognostic (1.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.27e-1)" "unprognostic (3.75e-2)" "unprognostic (7.33e-3)" "prognostic favorable (5.54e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (2.87e-1)" "unprognostic (1.81e-1)" "unprognostic (5.37e-2)" "prognostic favorable (2.94e-4)" 3.4 7.5 3.3 6.3 2.9 13.1 3.8 8.7 3.7 6.7 2.6 7.7 2.6 4.6 2.8 4.7 6.5 3.8 4.4 3.0 3.0 3.8 1.1 4.4 12.6 3.5 3.6 8.2 2.1 1.8 6.7 3.3 3.4 5.0 7.1 5.1 12.0 3.6 1.1 6.1 7.3 3.7 3.3 10.2 3.4 6.3 3.4 8.4 3.3 0.8 11.3 5.7 5.1 3.7 0.1 0.0 7.5 8.9 2.2 2.5 0.0 1.9 4.0 2.2 6.6 0.7 3.2 7.5 6.3 1.6 5.4 5.6 8.4 2.5 1.5 5.8 3.0 6.5 0.7 0.0 1.9 6.8 0.5 3.3 2.4 2.5 2.5 3.8 2.8 4.9 4.3 11.8 1.6 5.5 6.5 20.7 3.5 8.0 3.1 5.3 2.4 6.4 1.8 3.0 1.2 2.7 2.6 2.6 0.2 3.2 2.8 12.5 1.6 5.6 3.2 0.0 2.2 13.5 11.2 11.3 1.9 19.0 1.1 0.0 1.6 1.4 2.9 1.4 3.8 3.3 3.4 3.5 2.3 3.5 5.2 3.4 0.8 1.9 1.8 2.2 2.0 2.5 3.3 2.9 8.7 3.7 3.0 3.0 3.5 3.6 3.4 3.3 3.4 3.7 6.8 12.8 5.8 0.0 7.3 0.0 0.0 0.0 0.0 0.0 7.2 14.0 0.0 0.0 3.7 3.7 0.0 2.1 15.9 0.0 0.0 1.3 0.0 16.0 5.3 3.3 0.0 0.0 0.0 1.6 0.3 3.3 0.0 11.1 25.2 7.3 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.3 0.0 0.0 1.0 6.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.8 6.9 11.1 0.0 0.0 IP6K1 "IHPK1, KIAA0263" ENSG00000176095 "Inositol hexakisphosphate kinase 1" Q92551 3 49724294-49786542 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040825 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040825: AB_10960426" "unprognostic (6.18e-2)" "unprognostic (1.33e-1)" "unprognostic (3.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.99e-1)" "prognostic favorable (2.08e-4)" "unprognostic (9.97e-3)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "prognostic favorable (6.85e-4)" "unprognostic (1.29e-2)" "prognostic favorable (5.77e-5)" "unprognostic (8.75e-2)" "unprognostic (1.67e-1)" "unprognostic (9.24e-2)" "unprognostic (1.64e-2)" 17.9 20.2 32.4 12.1 33.6 12.5 17.2 27.6 34.9 21.5 17.2 24.1 12.1 25.6 12.2 20.0 19.4 12.9 15.8 35.9 27.7 21.3 14.6 17.5 13.3 26.4 28.2 25.5 19.8 22.8 21.5 16.4 27.4 18.1 11.3 18.3 17.4 17.2 12.6 23.1 17.8 16.9 24.5 21.9 18.5 32.2 30.7 17.2 16.2 11.4 13.2 19.1 16.0 29.0 20.6 24.5 27.9 33.1 28.6 21.8 22.5 26.6 27.8 42.7 37.3 31.9 20.9 17.3 16.8 29.7 28.8 14.9 39.8 24.2 24.0 35.6 30.6 40.5 36.1 21.8 31.4 25.0 26.7 25.6 29.4 46.4 27.8 24.0 36.1 20.3 26.7 20.3 21.4 18.2 30.6 25.6 30.2 16.1 37.6 19.1 19.8 35.7 27.7 30.8 15.0 29.8 33.4 21.8 30.6 16.0 17.6 36.2 32.8 23.9 23.6 33.1 31.0 24.3 35.6 18.8 21.9 28.4 24.9 4.7 7.3 12.1 11.7 5.4 11.4 6.0 10.4 12.8 5.6 8.4 12.6 12.7 33.3 10.3 7.0 4.1 11.8 9.5 32.4 33.6 27.6 34.9 35.9 27.7 26.4 28.2 27.4 24.5 30.7 29.0 17.1 25.6 12.3 24.5 25.0 15.6 14.7 7.4 11.4 38.4 19.7 15.0 8.8 18.6 10.1 12.9 89.6 19.2 27.6 22.0 5.9 14.5 88.2 24.9 19.9 19.0 27.6 24.2 42.3 13.0 16.1 14.7 14.8 17.3 19.7 19.6 19.6 12.2 12.8 30.3 46.6 14.1 10.2 15.0 14.2 23.7 21.1 17.8 19.6 31.9 15.9 19.6 35.0 43.7 39.8 19.2 8.8 16.6 28.9 19.6 14.6 12.5 21.8 78.3 19.7 16.2 18.3 24.6 21.9 13.7 18.8 27.5 27.6 30.5 12.8 20.4 IP6K2 IHPK2 ENSG00000068745 "Inositol hexakisphosphate kinase 2" Q9UHH9 3 48688003-48740353 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007532, HPA070811" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA007532: AB_1851542, HPA070811: AB_2732165" "prognostic favorable (1.25e-4)" "unprognostic (2.55e-2)" "unprognostic (8.86e-2)" "unprognostic (6.69e-3)" "unprognostic (1.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.76e-3)" "prognostic favorable (2.95e-4)" "unprognostic (6.57e-3)" "unprognostic (1.56e-1)" "unprognostic (1.92e-3)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" "unprognostic (3.50e-2)" "prognostic favorable (1.83e-4)" 57.6 96.3 53.1 39.5 57.2 130.1 80.1 84.6 57.8 117.2 52.8 106.0 79.8 101.8 108.4 95.4 78.3 47.9 62.3 53.7 58.4 106.9 83.5 55.4 53.7 56.2 53.3 99.1 91.2 48.0 121.8 44.8 55.1 111.6 88.0 63.7 88.7 42.2 45.8 145.4 89.1 43.1 49.7 78.9 79.5 55.5 55.2 72.2 108.8 31.5 43.5 66.7 113.4 64.2 25.9 49.5 100.6 71.2 55.5 69.3 72.6 48.0 54.0 54.0 62.2 41.1 67.0 45.5 38.7 45.5 67.8 65.3 50.6 72.1 50.0 54.1 44.9 52.2 172.7 89.5 45.0 50.3 48.9 65.7 103.0 73.3 59.7 71.8 76.2 143.8 39.5 55.4 63.9 57.3 107.4 68.3 77.4 50.0 90.4 44.4 33.3 50.0 73.7 121.7 62.4 94.6 103.9 69.5 53.0 79.6 67.7 83.3 54.8 58.3 57.4 37.0 48.7 50.6 65.4 64.2 53.3 57.7 52.4 158.1 50.5 92.7 63.4 50.8 57.6 60.8 55.1 60.4 50.1 60.2 51.1 52.7 80.3 67.5 65.3 52.0 84.2 46.8 53.1 57.2 84.6 57.8 53.7 58.4 56.2 53.3 55.1 49.7 55.2 64.2 63.3 70.5 52.9 38.5 41.3 83.1 87.2 182.5 174.2 66.5 69.9 77.5 12.9 38.6 109.1 99.3 39.6 114.3 39.4 157.4 76.3 58.7 43.8 50.8 64.8 46.1 110.2 40.1 31.1 47.4 73.9 73.7 64.2 56.9 54.5 60.3 32.5 25.1 41.4 20.2 40.6 108.6 150.5 16.6 33.5 16.4 81.1 24.5 26.6 22.5 30.3 32.4 44.3 50.8 52.6 60.5 105.7 68.4 34.0 59.0 84.7 65.5 68.4 56.0 52.6 31.5 50.6 71.6 57.9 90.3 83.0 124.0 43.3 87.9 89.8 89.3 IPCEF1 "KIAA0403, PIP3-E" ENSG00000074706 "Interaction protein for cytohesin exchange factors 1" Q8WWN9 6 154154496-154356792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 17.7;brain: 13.6;lymphoid tissue: 13.5;thyroid gland: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 46.1;Excitatory neurons: 120.0;Microglial cells: 252.9;T-cells: 65.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 71.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "HMC-1: 19.8;THP-1: 10.5;U-937: 11.0" "Low region specificity" "Detected in all" "HPA028708, HPA028710" Supported Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: AB_10601916, HPA028710: AB_2732442" "unprognostic (1.23e-2)" "unprognostic (8.93e-3)" "unprognostic (4.18e-2)" "unprognostic (5.63e-3)" "unprognostic (2.05e-1)" "unprognostic (6.55e-3)" "unprognostic (1.30e-3)" "unprognostic (2.57e-2)" "unprognostic (3.87e-1)" "unprognostic (5.84e-2)" "unprognostic (3.27e-2)" "unprognostic (4.87e-2)" "unprognostic (5.01e-2)" "unprognostic (8.64e-2)" "unprognostic (5.45e-2)" "unprognostic (1.42e-2)" "unprognostic (1.51e-4)" 0.7 0.2 8.4 7.9 5.4 17.7 1.5 4.1 13.6 2.7 0.0 1.3 0.7 1.1 1.4 1.4 2.1 2.9 0.6 5.4 3.2 2.8 2.0 1.5 13.5 0.0 7.4 0.6 0.7 0.1 0.6 1.6 0.0 0.8 1.2 0.2 1.2 0.4 0.2 0.5 2.3 0.9 0.0 6.8 2.4 0.9 12.2 10.6 39.1 0.2 12.8 2.1 0.5 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 19.8 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 3.1 1.2 0.8 0.0 0.5 0.1 0.1 0.3 0.7 2.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 11.0 0.0 3.2 14.5 71.6 13.0 6.5 27.6 0.0 16.3 12.5 16.2 0.1 27.9 16.8 42.7 14.3 8.5 0.4 22.6 12.6 8.4 5.4 4.1 13.6 5.4 3.2 0.0 7.4 0.0 0.0 12.2 5.4 1.1 0.0 1.7 7.8 3.5 0.6 0.5 0.4 12.0 0.6 1.8 1.0 1.1 1.5 1.7 1.8 0.0 1.7 46.1 0.0 7.9 2.1 1.3 2.0 1.2 2.3 0.0 3.2 120.0 0.0 0.1 1.0 3.1 2.5 0.0 0.1 3.3 1.1 2.8 3.3 9.8 0.5 2.0 23.4 15.2 0.3 0.3 15.2 0.0 252.9 17.9 0.2 27.8 9.0 14.6 0.0 0.1 0.4 20.7 0.6 0.1 2.0 1.3 0.2 0.0 3.4 0.4 0.2 1.1 4.0 0.6 2.7 65.5 2.0 0.3 1.3 IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 155.3;Spermatogonia: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 131.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" 11.6 11.2 9.6 14.7 10.0 20.4 23.1 11.0 10.5 15.7 10.8 13.0 12.0 15.5 19.7 12.5 16.6 12.1 9.7 10.1 10.1 12.2 8.9 12.3 24.3 9.7 9.5 17.9 18.3 13.9 15.3 11.5 9.5 15.9 16.2 18.9 15.6 15.5 11.4 15.5 14.1 11.8 9.7 18.3 12.3 28.9 10.4 22.1 10.5 5.7 25.7 14.2 13.7 11.0 38.3 10.1 48.9 55.5 7.5 11.6 57.2 17.4 10.8 19.7 23.8 33.6 18.1 76.8 23.9 10.1 30.2 28.7 30.5 14.5 29.3 15.1 23.8 51.2 22.2 28.7 20.0 64.1 14.8 7.4 27.2 13.7 30.3 10.2 15.2 32.4 31.0 27.9 22.3 19.3 41.7 44.5 40.1 22.6 18.1 40.4 23.4 24.9 11.4 16.9 26.0 20.9 17.3 12.2 31.3 16.0 10.8 49.4 12.9 18.5 22.4 9.1 23.4 66.4 44.9 131.2 17.9 29.0 17.1 3.2 6.6 11.7 7.2 12.3 10.5 22.8 9.8 9.0 9.6 21.6 11.5 7.2 2.8 12.2 14.1 8.7 11.7 6.4 9.6 10.0 11.0 10.5 10.1 10.1 9.7 9.5 9.5 9.7 10.4 11.0 15.8 6.4 15.0 48.3 28.4 18.9 19.2 20.0 19.9 15.2 19.6 17.3 8.4 11.5 26.5 11.0 27.1 26.6 21.9 7.7 3.9 11.1 3.7 31.1 12.7 11.2 7.2 21.5 60.1 12.9 8.2 15.4 11.7 12.6 8.8 21.9 6.8 6.2 10.5 13.5 66.8 8.6 20.3 9.8 14.1 7.4 15.5 11.3 14.2 51.5 15.8 12.8 17.5 49.3 59.5 13.9 8.2 13.5 45.2 15.7 7.9 7.5 69.2 27.7 13.1 17.8 15.9 155.3 96.5 16.2 20.6 14.1 19.9 8.4 11.9 16.3 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 IQSEC1 "ARF-GEP100, BRAG2, GEP100, KIAA0763" ENSG00000144711 "IQ motif and Sec7 domain ArfGEF 1" Q6DN90 3 12897043-13283281 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 183.0;Cone photoreceptor cells: 193.9;Excitatory neurons: 191.3;Horizontal cells: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 66.5;U-266/84: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038143, HPA038144" Uncertain Supported "Nucleoli,Nucleoli rim,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Vesicles" "HPA038143: AB_10697241, HPA038144: AB_2675860" "prognostic unfavorable (3.03e-5)" "unprognostic (1.80e-1)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (8.19e-3)" "unprognostic (2.64e-3)" "unprognostic (5.60e-2)" "unprognostic (1.67e-1)" "unprognostic (3.00e-1)" "unprognostic (1.14e-2)" "prognostic favorable (9.07e-4)" "unprognostic (4.42e-1)" "prognostic favorable (3.58e-6)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.00e-3)" "unprognostic (4.65e-2)" 26.8 38.7 37.0 19.3 49.4 54.9 19.7 13.9 85.6 20.5 0.0 19.6 7.0 19.6 7.4 9.2 19.5 11.0 35.3 42.7 19.9 16.8 30.9 28.4 24.6 48.1 14.2 21.1 19.3 30.9 18.5 19.0 50.6 22.4 7.1 56.3 15.3 13.7 34.4 12.8 22.3 12.3 4.3 46.6 17.7 10.8 17.6 14.0 16.1 27.0 16.4 19.6 15.3 55.1 10.2 13.3 11.4 12.5 9.6 12.8 66.5 10.8 9.1 7.2 5.5 9.1 8.1 21.2 12.0 20.1 7.9 5.8 9.0 5.7 5.3 14.1 19.0 12.6 8.0 38.0 10.3 0.2 5.1 13.0 10.6 14.7 8.3 9.6 6.7 8.6 36.0 20.6 5.1 31.6 8.2 13.1 12.3 7.6 26.4 11.3 3.9 29.6 4.4 12.8 9.5 18.2 7.4 27.5 6.5 10.4 11.6 8.6 17.5 7.5 19.2 6.4 1.5 43.6 64.7 8.1 14.2 6.0 6.1 4.5 2.7 3.9 2.5 2.9 1.9 5.0 1.7 1.9 1.4 4.3 1.7 2.0 8.3 1.3 2.8 4.9 1.3 2.1 37.0 49.4 13.9 85.6 42.7 19.9 48.1 14.2 50.6 4.3 17.6 55.1 29.1 3.2 17.9 59.7 45.6 11.5 7.9 7.8 12.0 110.1 16.1 15.9 183.0 21.5 10.7 3.7 193.9 9.9 48.5 3.4 7.9 6.8 2.9 7.3 13.2 29.8 10.2 46.3 191.3 12.9 42.2 22.8 8.2 5.0 15.2 21.6 24.7 42.7 22.0 235.6 128.4 13.3 4.1 60.4 42.4 4.8 16.8 34.2 7.2 78.7 36.3 16.6 45.3 67.3 78.8 7.8 3.8 22.6 23.3 19.0 3.0 5.8 29.1 123.1 26.3 24.9 30.6 2.2 1.7 3.5 7.7 21.8 24.8 45.2 8.5 13.2 IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 33.4" "Group enriched" "Detected in many" 7 "Early spermatids: 283.9;Endometrial ciliated cells: 82.6;Late spermatids: 157.5;Respiratory ciliated cells: 88.2;Spermatocytes: 116.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Nucleoplasm, Intermediate filaments, Cytosol" "HPA049626: AB_2732554" "unprognostic (8.71e-2)" "unprognostic (1.25e-2)" "unprognostic (1.98e-1)" "unprognostic (6.42e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (6.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "unprognostic (3.76e-1)" "unprognostic (5.44e-6)" "unprognostic (2.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.14e-1)" "unprognostic (7.30e-2)" 0.1 0.6 0.2 0.0 0.4 0.0 0.5 1.7 0.9 0.8 3.9 0.1 0.0 0.7 1.1 0.0 5.0 0.8 0.1 0.2 0.5 3.0 0.0 0.8 0.0 1.8 2.0 0.2 0.3 1.7 1.0 0.1 1.3 0.5 0.0 1.1 0.2 0.6 0.1 0.1 0.0 0.2 1.0 0.0 0.1 33.4 0.6 0.0 3.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.7 0.9 0.2 0.5 1.8 2.0 1.3 1.0 0.6 0.4 1.1 6.4 0.5 19.6 0.0 0.5 0.7 3.8 0.0 2.5 1.9 1.8 1.8 0.0 11.4 18.4 4.2 0.4 0.1 0.1 1.9 1.1 283.9 82.6 3.2 0.9 1.8 0.0 12.0 0.4 0.3 1.1 0.0 1.7 1.3 0.3 0.7 0.0 0.1 3.3 8.6 0.2 8.2 0.0 0.3 157.5 2.5 0.4 0.0 4.7 0.3 1.8 0.0 5.0 2.6 0.2 0.0 3.0 0.0 0.5 0.0 5.7 88.2 9.0 6.6 0.7 2.7 116.2 6.0 0.2 0.1 0.7 0.3 2.9 0.0 0.3 IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43789543 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 56.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Approved Nucleoli,Microtubules,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Nucleoli, Cytosol" "CAB016685: AB_1618505, CAB022077: " "unprognostic (2.76e-2)" "unprognostic (5.63e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.46e-5)" "unprognostic (6.15e-2)" "unprognostic (3.50e-3)" "unprognostic (1.44e-2)" "unprognostic (8.49e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (4.00e-3)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "prognostic favorable (4.42e-5)" 8.6 6.5 4.0 13.6 4.6 10.0 8.9 4.5 5.1 7.9 5.1 7.9 9.1 6.8 7.0 10.5 7.0 8.8 5.4 3.9 4.6 8.0 9.2 8.5 17.5 5.5 4.7 5.6 15.1 6.9 6.2 8.3 5.4 7.5 8.4 12.3 8.4 7.0 3.0 13.3 11.9 7.2 4.8 18.6 10.5 5.8 4.9 18.5 10.9 3.2 16.3 7.8 7.9 5.3 9.3 6.8 4.7 6.2 16.5 27.6 6.7 12.9 9.1 10.0 9.1 5.8 8.7 15.8 12.4 10.7 6.6 7.5 5.3 8.3 14.2 22.8 4.9 15.2 5.2 3.7 9.4 21.2 17.7 14.7 12.7 12.7 7.4 17.4 15.0 15.1 14.4 11.6 27.8 5.1 18.6 11.7 1.7 0.0 7.9 12.2 5.8 8.4 7.8 8.8 3.4 3.3 6.3 7.9 6.2 6.4 9.9 18.5 13.4 12.2 2.3 15.1 9.0 14.0 19.4 13.7 12.7 56.2 6.9 20.8 4.0 8.7 6.1 4.6 6.3 3.3 4.9 5.3 3.7 4.4 4.4 4.8 7.9 7.9 5.9 5.1 6.7 4.6 4.0 4.6 4.5 5.1 3.9 4.6 5.5 4.7 5.4 4.8 4.9 5.3 24.1 19.2 15.6 5.2 36.5 10.8 11.3 10.7 17.1 5.8 15.2 11.2 4.5 17.2 11.3 33.1 20.9 14.9 52.1 15.7 21.5 12.7 18.4 14.1 12.4 17.3 3.6 12.0 2.9 17.8 8.4 13.7 33.6 15.2 22.1 10.7 16.1 8.7 16.9 8.4 3.4 11.9 14.2 24.7 20.2 23.2 12.5 25.1 10.6 20.6 28.2 9.9 60.8 2.5 14.7 13.3 7.2 11.3 33.2 8.9 18.6 13.8 9.5 27.2 6.6 9.5 11.0 28.2 12.5 17.2 11.8 27.9 41.1 15.0 9.2 13.5 IRF2 ENSG00000168310 "Interferon regulatory factor 2" P14316 4 184387729-184474550 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 163.6;Karpas-707: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030813, CAB032306, HPA057327" Supported Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Cell Junctions, Cytosol" "CAB032306: AB_2249157, HPA030813: AB_10600718, HPA057327: AB_2683410" "prognostic favorable (6.95e-5)" "unprognostic (1.69e-3)" "unprognostic (5.43e-2)" "unprognostic (1.59e-3)" "unprognostic (2.70e-2)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-3)" "unprognostic (2.90e-2)" "unprognostic (4.00e-2)" "unprognostic (2.35e-1)" "unprognostic (6.87e-3)" "unprognostic (8.55e-3)" "unprognostic (5.25e-2)" "prognostic favorable (8.34e-5)" "unprognostic (1.31e-3)" 25.1 30.1 18.2 47.8 23.4 18.0 21.9 22.1 19.3 25.6 21.4 27.8 31.1 21.8 22.7 26.7 25.3 24.9 19.5 17.5 21.9 18.5 37.4 27.6 62.5 25.3 22.1 28.1 14.8 20.2 12.3 28.9 25.2 20.6 28.7 9.3 29.1 21.2 28.1 19.4 33.3 23.2 21.7 54.9 31.5 6.1 23.5 49.8 21.7 23.8 52.2 35.6 22.5 29.6 20.3 14.9 17.5 12.0 37.4 37.9 10.5 14.4 44.8 34.8 36.0 4.2 37.9 12.2 7.4 21.7 28.4 18.3 12.0 27.4 22.1 163.6 6.6 34.4 7.9 26.8 37.1 21.1 27.7 41.2 24.8 19.8 50.1 29.8 26.7 14.5 6.9 165.3 14.6 14.1 40.6 25.8 4.0 18.5 10.7 52.7 6.9 55.1 26.6 30.4 7.5 11.6 20.4 16.8 31.3 7.3 13.0 18.9 22.0 9.9 10.7 11.3 12.8 47.3 40.6 11.0 20.9 20.3 17.8 106.7 95.7 175.8 76.4 126.3 77.9 104.9 74.5 82.2 79.6 107.7 78.8 78.8 407.6 94.8 145.7 20.2 111.7 100.3 18.2 23.4 22.1 19.3 17.5 21.9 25.3 22.1 25.2 21.7 23.5 29.6 58.9 38.5 24.5 53.5 68.9 49.1 50.5 60.4 45.5 13.1 25.8 27.3 21.9 27.1 36.0 25.8 6.2 31.3 48.8 40.3 37.2 30.9 0.2 53.4 40.2 42.9 30.6 62.7 23.8 30.1 16.2 35.8 34.1 63.2 26.6 23.1 38.2 37.6 48.5 20.2 27.8 29.5 44.7 90.3 53.5 3.0 37.3 65.9 19.6 41.2 144.0 23.4 70.0 43.7 77.1 28.7 38.9 53.0 63.4 72.9 42.1 46.1 58.7 8.4 39.5 25.4 44.8 0.6 2.4 49.5 44.5 26.7 56.3 37.7 22.8 70.9 IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.4;Theca cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005261: AB_649615, HPA046433: AB_2732524" "unprognostic (2.20e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.59e-2)" "unprognostic (3.86e-3)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-3)" "unprognostic (5.47e-2)" "unprognostic (2.24e-2)" "unprognostic (5.48e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.46e-2)" "unprognostic (6.92e-2)" "unprognostic (3.23e-2)" "unprognostic (7.55e-3)" 7.6 9.7 1.7 2.9 1.6 0.5 11.7 5.2 3.1 14.7 1.8 10.3 3.9 17.4 1.9 3.6 15.0 5.6 5.0 1.6 1.0 3.4 10.5 5.0 1.7 1.8 1.6 20.9 3.5 3.3 1.5 9.5 1.2 7.8 2.7 1.5 3.0 7.0 28.0 5.2 5.1 10.3 2.0 2.0 5.3 0.8 1.6 8.1 20.0 2.9 1.3 11.6 6.6 1.5 5.7 26.0 18.6 0.7 25.0 14.8 0.0 15.6 12.2 20.4 13.0 15.0 14.4 2.3 2.5 10.6 14.0 10.0 1.2 15.0 11.5 5.9 1.0 0.1 1.7 7.1 12.5 0.5 0.1 20.7 8.1 16.1 14.5 12.3 0.0 2.3 3.0 22.7 14.0 22.6 4.9 6.6 7.5 3.6 14.3 1.1 24.1 0.1 9.3 18.9 3.2 0.5 5.0 3.6 8.4 14.9 13.7 0.3 1.3 26.8 24.2 20.9 15.1 10.6 4.6 3.4 26.5 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.2 3.1 1.6 1.0 1.8 1.6 1.2 2.0 1.6 1.5 1.7 19.2 4.6 5.9 2.7 35.4 31.9 29.7 19.4 19.3 36.9 28.1 13.4 14.3 12.8 0.0 0.0 6.4 0.0 13.2 17.6 15.4 1.6 22.1 28.4 2.1 2.4 0.0 17.3 11.4 0.6 28.3 2.0 24.3 0.0 75.4 1.8 57.4 1.7 20.2 31.3 6.5 24.4 1.3 4.6 1.8 22.7 3.6 16.0 15.0 0.8 8.4 0.0 26.7 1.7 11.1 8.2 14.7 9.5 14.5 23.4 3.0 8.1 1.7 13.1 9.5 22.8 1.0 1.2 4.2 23.7 18.3 1.2 110.3 7.7 22.8 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 ISL1 "Isl-1, ISLET1" ENSG00000016082 "ISL LIM homeobox 1" P61371 5 51383448-51394730 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9;seminal vesicle: 19.2;vagina: 15.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 207.5;Cytotrophoblasts: 34.4;Enteroendocrine cells: 91.6;Horizontal cells: 43.7;Syncytiotrophoblasts: 34.2" "Group enriched" "Detected in some" 5 "cervical cancer: 1.1;pancreatic cancer: 4.1;prostate cancer: 2.1;stomach cancer: 1.6;testis cancer: 1.4" "Group enriched" "Detected in many" 5 "hypothalamus: 11.5;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 297.1" "Group enriched" "Detected in many" 8 "basal ganglia: 13.8;hypothalamus: 15.0;thalamus: 6.0" "Group enriched" "Detected in some" 9 "basal ganglia: 5.8;hypothalamus: 5.4" "HPA048613, HPA057416" Approved Approved "Nucleoplasm,Nuclear speckles,Mitochondria" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA048613: , HPA057416: AB_2683431" "unprognostic (4.97e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-1)" "unprognostic (2.41e-3)" "unprognostic (5.52e-2)" "unprognostic (6.79e-2)" "unprognostic (9.21e-2)" "unprognostic (9.42e-2)" "unprognostic (5.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (9.11e-3)" "unprognostic (4.39e-3)" 2.9 1.3 0.4 0.0 1.4 0.0 0.1 0.0 1.8 7.8 0.0 1.1 2.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 1.0 0.5 0.0 4.8 0.0 2.2 7.8 1.2 12.0 2.4 22.9 1.1 19.2 0.0 1.1 0.7 0.1 0.0 0.0 10.0 1.6 6.0 4.3 0.3 0.0 0.4 0.7 15.9 0.2 0.0 0.0 0.0 3.4 0.0 0.0 0.2 3.0 3.8 0.0 0.0 0.3 2.7 0.0 2.5 0.0 0.0 2.2 4.6 3.4 0.0 0.0 7.1 0.0 12.6 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.9 3.2 0.0 3.0 0.0 0.0 0.0 19.1 297.1 0.0 0.0 0.0 11.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 1.8 0.0 11.5 1.0 0.5 1.2 0.0 6.0 0.2 0.0 0.0 0.0 0.0 0.1 1.5 5.1 11.8 0.0 207.5 0.0 0.0 0.2 0.0 2.8 0.0 4.2 34.4 0.0 0.5 0.0 0.1 17.3 0.0 0.0 1.7 91.6 0.0 0.0 0.0 10.9 6.1 11.7 0.0 0.0 0.0 0.0 0.0 2.7 43.7 0.0 1.9 8.2 0.0 0.4 3.2 0.3 0.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 1.1 0.0 0.0 0.8 11.8 0.0 0.0 4.0 2.5 7.3 0.0 1.0 34.2 0.0 0.0 0.2 5.6 ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 6 "Astrocytes: 87.5;Cardiomyocytes: 124.5;Sertoli cells: 164.3;Skeletal myocytes: 65.8;Smooth muscle cells: 110.6" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 309.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" 133.4 8.2 18.5 18.5 21.2 1.8 69.0 15.9 30.2 28.7 16.1 97.8 17.7 45.5 12.3 23.9 56.1 30.8 157.9 34.5 17.8 11.5 10.2 15.5 6.4 21.2 21.1 19.1 5.1 6.1 12.6 1.9 20.3 33.9 8.9 2.4 14.9 37.3 262.3 16.0 27.4 95.2 16.4 10.2 35.2 8.9 23.8 3.4 26.1 154.1 3.3 46.5 25.5 21.0 0.2 4.1 7.5 12.3 66.5 13.4 0.7 5.4 8.7 11.7 11.8 8.4 6.5 2.3 7.4 3.4 0.9 1.1 5.1 0.3 10.0 0.2 3.8 0.8 2.8 3.2 0.5 0.3 2.7 19.1 0.2 64.2 0.3 309.1 0.2 2.2 0.9 1.6 37.8 5.3 0.3 3.1 20.9 1.7 0.4 0.1 28.7 0.6 0.2 0.2 0.9 2.8 0.6 0.2 48.0 4.0 0.9 13.9 0.0 1.3 12.4 0.8 8.4 3.2 2.2 0.9 57.8 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.5 21.2 15.9 30.2 34.5 17.8 21.2 21.1 20.3 16.4 23.8 21.0 11.9 0.0 0.0 87.5 0.3 1.9 0.5 0.1 0.6 2.4 1.2 3.4 124.5 2.8 0.0 1.8 4.2 0.0 0.3 0.7 0.0 0.3 0.3 1.1 1.2 9.5 7.7 0.4 17.6 0.0 0.1 5.0 0.5 1.1 0.0 6.2 0.7 1.4 0.6 0.0 9.4 1.8 0.0 1.9 2.7 0.1 6.5 2.2 3.6 9.4 0.0 3.4 0.0 6.6 3.7 0.3 0.1 6.4 0.1 0.8 2.6 0.8 0.1 0.6 164.3 65.8 110.6 4.1 2.9 0.7 2.3 0.1 0.5 0.3 0.9 0.3 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 ITGB1BP1 "ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B" ENSG00000119185 "Integrin subunit beta 1 binding protein 1" O14713 2 9403475-9423528 "Predicted intracellular proteins" "Angiogenesis, Biomineralization, Cell adhesion, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 391.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067348, HPA071538" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA067348: AB_2732765, HPA071538: AB_2686413" "unprognostic (2.21e-1)" "unprognostic (8.31e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.39e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (4.67e-5)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (6.46e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (3.75e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-3)" "unprognostic (4.08e-3)" 113.7 23.2 45.5 19.3 63.1 31.3 60.4 50.3 58.0 43.7 49.3 37.3 13.6 31.0 26.6 20.9 24.3 22.6 37.3 46.4 48.3 50.2 13.3 22.8 22.1 48.2 47.0 22.3 11.8 26.2 19.1 24.2 49.9 18.5 24.2 27.5 15.5 23.7 29.8 29.7 19.1 35.9 41.8 15.2 22.9 9.4 54.3 27.0 22.4 33.5 25.7 30.4 32.5 52.7 53.5 35.4 43.4 51.5 148.9 131.2 23.3 94.9 66.2 83.8 66.1 49.5 33.1 55.6 43.1 135.9 56.1 50.1 66.3 62.7 92.8 158.6 30.2 53.2 43.2 61.1 54.1 42.2 57.4 70.5 49.5 78.4 56.5 75.2 76.6 43.0 29.9 46.1 109.0 44.6 74.7 25.5 35.9 90.3 53.9 39.4 59.1 51.4 88.5 40.6 44.1 45.0 54.8 40.3 71.3 38.9 30.5 32.1 48.6 73.8 54.5 103.3 105.7 46.8 111.0 89.0 106.1 54.8 54.5 86.1 43.1 56.0 54.9 54.0 52.5 40.1 46.6 53.2 56.8 33.0 35.2 45.7 9.3 50.4 41.1 52.8 61.7 53.1 45.5 63.1 50.3 58.0 46.4 48.3 48.2 47.0 49.9 41.8 54.3 52.7 90.0 28.9 18.1 18.3 47.1 61.2 40.6 70.4 40.9 25.2 30.4 41.8 104.3 22.8 35.1 38.6 2.1 45.0 70.7 16.1 391.3 72.0 26.3 31.3 51.9 85.5 33.1 49.4 61.6 72.7 73.9 98.6 25.5 30.9 41.7 44.4 53.6 21.6 91.4 35.3 47.3 30.4 32.6 45.0 88.5 25.7 54.3 51.7 97.8 15.9 95.6 64.2 121.5 25.6 40.1 108.9 27.0 57.2 42.7 35.2 24.7 88.4 35.6 30.6 92.1 49.0 102.4 27.8 19.0 47.5 63.1 31.5 63.0 70.7 35.2 60.4 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 ITM2A "BRICD2A, E25A" ENSG00000078596 "Integral membrane protein 2A" O43736 X 79360384-79367667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 322.9" "Cell type enhanced" "Detected in many" "Adipocytes: 390.0;Endothelial cells: 368.4;Fibroblasts: 302.1;granulocytes: 194.6;Leydig cells: 335.5;Muller glia cells: 188.9;T-cells: 239.2" "Cancer enhanced" "Detected in all" "glioma: 51.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 172.6;eosinophil: 88.5;gdT-cell: 107.1;MAIT T-cell: 79.3;memory CD4 T-cell: 204.7;memory CD8 T-cell: 170.5;naive CD4 T-cell: 216.7;naive CD8 T-cell: 101.6;NK-cell: 130.3;T-reg: 168.1" "Group enriched" "Detected in all" 7 "granulocytes: 172.6;NK-cells: 130.3;T-cells: 216.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 1749.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000296 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Golgi apparatus, Plasma membrane" "HPA000296: " "unprognostic (1.05e-2)" "unprognostic (5.22e-3)" "unprognostic (2.77e-3)" "unprognostic (5.65e-2)" "unprognostic (1.73e-2)" "unprognostic (1.06e-3)" "prognostic favorable (3.66e-6)" "unprognostic (1.57e-1)" "unprognostic (4.94e-2)" "unprognostic (9.85e-2)" "unprognostic (1.33e-2)" "unprognostic (2.57e-1)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.31e-1)" "unprognostic (2.18e-1)" "unprognostic (4.30e-1)" 80.2 10.8 103.4 26.8 95.2 45.8 74.5 99.4 172.0 55.3 75.5 30.5 15.1 44.4 18.8 40.1 42.8 28.8 115.3 92.1 105.4 20.6 6.3 52.2 87.2 101.5 102.2 181.4 10.0 14.9 21.0 29.7 102.0 22.8 32.2 11.9 74.9 22.4 41.2 25.0 22.1 56.6 95.2 24.5 24.2 15.9 109.8 322.9 83.1 75.2 46.9 42.3 26.0 95.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 216.6 2.5 0.0 4.4 0.0 69.9 0.0 0.0 0.0 113.1 124.2 19.5 0.0 0.0 0.0 0.1 0.0 333.3 80.2 0.0 0.0 0.0 1749.0 77.6 25.0 0.0 0.0 0.7 0.1 0.3 64.6 0.0 0.2 19.0 0.0 0.9 0.0 17.6 2.2 2.5 3.0 0.0 1.8 0.4 1.1 208.1 0.0 0.0 0.2 0.0 8.7 172.6 0.8 88.5 107.1 1.3 79.3 23.4 204.7 170.5 0.8 23.5 216.7 101.6 3.9 130.3 1.1 6.1 168.1 115.3 103.4 95.2 99.4 172.0 92.1 105.4 101.5 102.2 102.0 95.2 109.8 95.8 390.0 3.2 14.8 1.0 28.0 67.4 13.2 2.1 50.1 3.1 21.1 81.9 29.3 2.8 4.4 1.8 0.0 0.4 64.8 2.1 5.9 0.4 3.1 0.4 2.6 368.4 2.4 42.7 3.5 50.9 0.2 302.1 29.6 0.6 194.6 1.4 135.0 1.0 1.3 1.7 2.3 85.6 0.0 9.5 39.5 7.1 335.5 8.6 62.2 114.3 3.2 188.9 65.9 18.1 60.2 1.0 1.4 117.8 81.8 12.3 0.2 1.4 0.7 12.1 0.0 31.8 22.5 0.5 2.6 24.3 47.0 0.3 239.2 2.0 2.9 2.5 ITPRID2 "CS-1, KIAA1927, KRAP, SPAG13, SSFA2" ENSG00000138434 "ITPR interacting domain containing 2" P28290 2 181891730-181930738 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 175.8" "Cell type enhanced" "Detected in some" "Adipocytes: 30.7;Cardiomyocytes: 30.0;Cytotrophoblasts: 25.7;Extravillous trophoblasts: 26.8;Hofbauer cells: 20.4;Syncytiotrophoblasts: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 6.1;monocytes: 5.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034665, HPA039989" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" Nucleoplasm "HPA034665: AB_2674271, HPA039989: AB_2676788" "unprognostic (1.68e-1)" "unprognostic (3.27e-2)" "unprognostic (2.17e-2)" "unprognostic (4.70e-2)" "unprognostic (8.77e-2)" "unprognostic (8.87e-2)" "unprognostic (2.13e-1)" "unprognostic (4.74e-2)" "unprognostic (5.63e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.95e-2)" "prognostic favorable (2.91e-5)" "unprognostic (3.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (5.79e-5)" 30.8 20.7 55.0 20.6 62.9 42.4 32.1 57.2 66.2 30.9 50.3 50.4 36.4 25.8 18.4 22.8 20.3 37.7 24.4 45.5 61.5 48.4 79.3 44.9 17.6 65.2 60.5 13.6 175.8 20.9 18.3 34.7 63.3 34.0 44.2 16.9 69.9 17.1 31.9 112.9 34.0 25.6 57.3 32.4 56.1 37.4 62.6 24.1 36.5 23.4 16.0 31.3 29.5 61.1 56.0 25.8 71.6 12.6 53.8 41.3 21.7 94.6 82.6 29.1 37.0 25.9 56.0 1.2 30.7 59.7 31.5 46.2 14.5 41.6 56.6 25.2 20.3 52.5 106.6 23.5 45.7 28.5 48.9 30.0 64.4 51.3 57.7 66.7 145.8 22.3 25.0 29.5 82.9 28.7 25.4 41.0 5.0 47.0 62.5 18.7 29.3 19.2 87.0 16.3 13.7 12.1 55.7 19.7 91.0 27.6 14.2 61.6 68.1 73.1 37.0 27.5 50.3 20.9 9.4 21.9 34.0 17.1 57.2 6.1 2.8 4.2 0.9 2.7 0.6 0.4 0.6 0.6 2.7 0.9 0.8 0.7 4.7 0.8 5.1 2.1 0.4 1.3 55.0 62.9 57.2 66.2 45.5 61.5 65.2 60.5 63.3 57.3 62.6 61.1 30.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 25.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 26.8 7.7 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 33.4 1.1 0.0 0.0 0.0 IVL ENSG00000163207 Involucrin P07476 1 152908546-152911886 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 162.3;esophagus: 298.3;salivary gland: 94.5;skin 1: 160.9;vagina: 235.2" "Cell type enhanced" "Detected in some" "Club cells: 10.4;Squamous epithelial cells: 30.8;Suprabasal keratinocytes: 71.0;Urothelial cells: 13.3" "Group enriched" "Detected in many" 5 "cervical cancer: 44.0;head and neck cancer: 145.4;melanoma: 50.9;urothelial cancer: 47.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "HaCaT: 292.9;RT4: 76.9;SK-BR-3: 86.3" "Not detected" "Not detected" "CAB002243, HPA055211" Enhanced Supported "Nuclear bodies,Centrosome,Cytosol" NA NA 4700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Nuclear bodies, Centrosome" "CAB002243: AB_563785, HPA055211: AB_2682739" "unprognostic (3.29e-4)" "unprognostic (1.91e-1)" "unprognostic (2.92e-2)" "unprognostic (2.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (4.82e-2)" "unprognostic (3.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.22e-2)" "unprognostic (1.32e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.0 162.3 0.0 0.0 0.0 0.0 18.2 298.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.0 94.5 0.1 0.4 160.9 0.1 0.0 0.0 0.1 0.2 0.1 0.0 3.5 0.1 0.0 36.9 17.4 235.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 292.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 0.0 0.0 0.0 86.3 0.0 0.2 3.6 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 3.1 3.5 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.6 0.0 0.0 30.8 71.0 0.0 0.1 0.0 0.0 13.3 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 JPT1 "ARM2, HN1, HN1A" ENSG00000189159 "Jupiter microtubule associated homolog 1" Q9UK76 17 75135248-75168281 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 406.9" "Cell type enhanced" "Detected in many" "Ductal cells: 371.3;Exocrine glandular cells: 437.2;Extravillous trophoblasts: 1344.2;monocytes: 375.7;Pancreatic endocrine cells: 1434.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 767.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059729 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA 40000 "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA059729: AB_2684114" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-3)" "unprognostic (3.57e-3)" "unprognostic (6.71e-2)" "unprognostic (2.51e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (3.58e-2)" "unprognostic (1.37e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.25e-3)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.77e-7)" "unprognostic (1.83e-1)" "unprognostic (8.99e-2)" "unprognostic (4.84e-2)" "unprognostic (1.51e-1)" 26.1 74.9 44.0 87.5 43.7 83.5 21.3 49.4 54.7 44.1 31.0 140.1 119.2 18.0 7.3 225.1 15.5 63.7 23.3 44.3 54.4 72.2 49.1 49.3 87.6 38.6 42.8 13.4 22.6 6.7 24.3 66.3 49.3 28.3 70.4 17.0 62.1 27.8 96.1 40.7 141.6 23.4 34.3 100.5 134.2 406.9 53.1 88.0 16.1 24.3 91.5 93.9 75.7 36.3 775.3 743.0 371.8 384.7 75.5 75.2 309.5 391.8 111.5 364.6 278.0 614.8 449.1 210.1 247.4 303.0 401.7 446.5 344.3 481.9 278.5 215.7 438.3 336.1 275.2 624.8 177.5 256.3 318.3 117.1 218.4 307.3 308.7 107.1 672.2 388.7 197.3 431.3 335.4 561.4 845.0 248.7 216.9 627.8 979.0 520.8 447.5 326.8 392.7 479.1 465.4 373.8 553.8 293.3 213.4 393.8 786.0 154.9 395.1 214.3 615.7 305.0 469.0 165.9 298.1 332.5 186.9 233.4 254.4 241.7 127.0 372.6 79.6 187.8 57.2 102.3 109.3 96.8 100.7 57.2 51.6 76.1 767.6 74.5 206.7 67.4 202.6 118.4 44.0 43.7 49.4 54.7 44.3 54.4 38.6 42.8 49.3 34.3 53.1 36.3 61.6 25.6 18.1 0.0 36.2 0.0 0.0 0.0 0.0 0.0 81.8 133.2 0.0 0.0 18.0 246.5 0.0 137.6 171.2 0.0 99.7 371.3 0.0 113.2 79.7 32.9 0.0 0.0 0.0 437.2 1344.2 40.4 0.0 194.0 7.6 179.6 0.0 0.0 319.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.5 0.0 0.0 375.7 0.0 0.0 0.0 0.0 1434.1 0.0 0.0 13.9 0.0 0.0 203.3 16.8 0.0 0.0 0.0 76.2 0.0 0.0 0.0 0.0 96.9 73.9 95.0 0.0 0.0 JRK "jerky, JH8" ENSG00000234616 "Jrk helix-turn-helix protein" O75564 8 142657460-142681968 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052675 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" No No "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA052675: AB_2681910" "unprognostic (3.65e-2)" "unprognostic (5.30e-2)" "unprognostic (9.67e-2)" "unprognostic (3.90e-3)" "unprognostic (1.27e-1)" "unprognostic (1.84e-2)" "unprognostic (6.58e-6)" "unprognostic (1.05e-1)" "unprognostic (3.87e-1)" "unprognostic (6.90e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (7.50e-2)" "unprognostic (2.07e-1)" "unprognostic (2.53e-1)" "unprognostic (1.22e-2)" "unprognostic (1.69e-2)" 3.7 4.5 5.9 4.1 6.1 2.1 4.0 7.9 7.4 7.4 4.0 5.9 3.0 6.7 3.4 4.9 5.5 2.5 5.9 5.8 4.7 7.9 4.0 3.9 5.4 6.2 5.2 8.5 5.4 4.6 6.4 3.0 5.5 6.2 2.8 3.8 4.7 4.0 7.5 6.0 5.3 3.7 4.3 7.2 5.7 6.6 6.2 5.1 6.9 4.7 5.9 5.7 4.7 6.8 6.5 6.9 8.0 6.4 7.6 10.8 4.8 10.4 4.2 11.9 6.8 6.3 13.1 11.0 4.1 8.2 8.2 8.7 7.0 6.2 6.0 8.5 12.0 11.2 25.3 7.2 3.1 8.6 7.5 7.2 5.4 7.6 4.3 6.0 6.8 13.1 12.0 4.8 10.1 11.1 10.1 4.8 6.8 4.6 9.6 13.1 5.0 6.2 4.1 11.1 14.5 9.6 18.1 7.3 4.3 5.0 7.3 5.2 8.1 9.1 19.5 9.1 5.5 6.3 7.6 6.3 6.9 10.7 9.0 1.0 0.7 0.9 0.9 0.5 0.5 0.4 1.0 0.9 0.7 1.2 1.3 1.0 0.8 0.6 0.2 0.6 0.6 0.4 5.9 6.1 7.9 7.4 5.8 4.7 6.2 5.2 5.5 4.3 6.2 6.8 3.5 6.4 1.1 8.5 4.8 0.0 2.5 0.0 2.2 14.7 4.5 3.3 11.5 4.3 0.6 7.3 20.9 4.4 8.6 3.2 3.9 2.8 1.9 1.4 4.9 6.5 9.1 12.0 11.3 2.5 2.7 3.7 6.6 2.1 1.3 15.5 8.2 2.6 3.0 10.1 11.0 3.1 0.0 6.6 0.0 2.2 11.5 3.4 0.0 8.4 4.5 4.4 12.3 9.5 9.5 5.6 1.4 11.7 4.3 3.7 2.7 2.7 0.7 10.0 0.0 5.8 4.8 9.1 19.4 3.2 0.0 2.2 2.5 6.8 4.2 4.5 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: AB_10674685, HPA038498: AB_2676046" "unprognostic (3.87e-3)" "unprognostic (6.18e-2)" "unprognostic (3.67e-1)" "unprognostic (8.89e-2)" "unprognostic (5.37e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.35e-3)" "unprognostic (6.16e-2)" "unprognostic (6.75e-3)" "unprognostic (4.19e-3)" "unprognostic (8.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "prognostic favorable (4.32e-4)" 11.9 11.4 6.0 8.2 7.0 41.8 12.2 8.6 8.0 13.9 7.3 11.8 8.1 14.1 11.5 13.3 12.6 7.7 13.4 6.5 6.9 12.2 9.8 10.9 13.9 7.0 6.5 16.3 9.7 12.2 9.3 12.2 6.7 11.1 9.3 11.8 13.0 8.3 40.7 13.4 11.9 9.8 6.7 13.2 10.8 14.6 6.8 14.2 11.5 23.1 13.8 12.4 12.8 8.8 19.5 26.5 21.8 12.8 25.6 22.0 48.1 20.8 17.6 35.9 19.5 45.2 25.1 31.9 39.0 25.5 14.0 18.3 37.1 23.5 29.5 30.4 22.5 37.1 20.2 12.9 29.2 40.0 13.9 20.8 31.2 25.5 46.2 18.0 17.2 24.8 43.7 20.9 25.0 18.7 39.2 29.2 28.6 28.1 26.0 33.4 21.3 35.9 17.2 27.1 25.1 17.6 43.2 30.0 25.7 21.8 40.2 43.4 12.8 25.5 18.9 10.9 19.7 29.8 50.7 46.2 12.4 89.5 13.6 35.3 19.7 23.5 25.1 21.2 23.7 27.3 23.9 25.9 25.8 23.8 27.9 26.9 9.0 24.3 23.0 20.2 32.2 24.0 6.0 7.0 8.6 8.0 6.5 6.9 7.0 6.5 6.7 6.7 6.8 8.8 18.0 3.2 14.3 9.8 24.7 11.9 14.7 17.9 32.5 15.6 15.7 15.5 10.9 8.6 15.0 14.7 29.2 22.5 36.5 10.2 9.8 13.3 24.4 8.2 13.9 13.7 9.0 14.1 11.5 9.8 12.5 15.1 12.2 12.4 11.4 19.8 14.6 9.6 11.9 15.2 13.8 9.1 10.2 11.9 13.2 13.8 12.5 13.7 16.0 7.5 14.8 8.2 11.3 15.1 18.8 12.2 4.7 10.1 16.9 12.1 10.8 15.6 10.2 22.8 26.3 15.7 16.6 38.5 34.8 19.9 11.2 25.3 30.6 15.9 12.4 9.8 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Vesicles, Cytosol" "HPA016953: AB_1851277, HPA074328: " "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favorable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 31.6 30.0 38.7 23.8 41.0 52.9 32.1 41.7 48.8 39.5 38.6 43.6 21.6 45.1 33.7 34.9 44.9 20.5 32.4 37.9 38.9 32.9 26.3 29.5 28.0 40.0 39.5 39.2 32.7 45.6 33.7 29.9 41.2 33.1 27.0 31.0 29.6 36.3 42.8 47.6 32.2 35.2 40.0 34.3 35.9 45.2 39.9 39.3 38.2 34.6 30.2 39.5 34.8 43.8 37.2 44.1 40.1 29.6 31.3 32.7 41.1 26.7 43.6 44.0 38.0 32.6 42.2 34.3 36.2 47.4 47.5 30.8 50.8 45.1 26.4 44.4 32.5 50.6 36.3 38.9 44.6 55.7 56.4 35.2 49.7 28.9 59.0 33.7 28.1 39.1 52.5 51.1 42.0 68.2 45.7 62.3 33.9 26.8 28.4 38.2 26.5 63.3 40.6 56.2 37.1 38.9 25.4 46.5 51.2 20.8 45.9 34.2 36.3 33.9 30.4 27.6 28.0 38.7 43.7 50.4 29.7 27.0 29.3 42.7 33.6 58.8 33.4 32.0 29.6 28.2 28.8 34.2 34.1 30.4 36.5 29.8 34.8 35.8 34.6 20.9 31.0 36.4 38.7 41.0 41.7 48.8 37.9 38.9 40.0 39.5 41.2 40.0 39.9 43.8 17.6 12.8 17.5 10.7 26.0 21.2 44.2 60.2 17.6 44.9 17.3 15.0 1.0 25.8 33.8 29.5 31.3 51.3 25.6 27.1 35.2 42.2 11.1 20.2 14.2 18.7 30.4 12.4 7.5 51.5 42.6 21.1 20.4 19.8 33.7 27.0 18.2 10.9 36.3 38.7 8.7 25.1 42.7 17.6 15.2 11.1 28.0 20.4 42.7 3.7 38.8 40.3 33.0 7.1 13.8 39.4 30.6 38.7 10.4 24.2 23.3 32.6 30.0 44.8 46.0 27.6 27.0 61.1 27.8 14.6 21.3 102.5 21.6 29.2 26.2 31.0 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KATNB1 ENSG00000140854 "Katanin regulatory subunit B1" Q9BVA0 16 57735739-57757244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041165, HPA041839" Enhanced Supported "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" Microtubules "HPA041165: AB_10795584, HPA041839: AB_10795598" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (1.56e-1)" "prognostic favorable (9.24e-4)" "unprognostic (2.54e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-1)" "prognostic favorable (8.44e-4)" "unprognostic (2.89e-2)" "unprognostic (1.03e-3)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (6.88e-2)" "unprognostic (1.54e-1)" 9.9 13.3 16.0 10.8 18.4 23.0 10.6 5.5 24.7 10.1 11.8 9.9 10.6 11.2 4.1 15.9 19.2 6.2 11.7 18.2 11.7 10.3 9.5 11.9 10.5 10.4 9.1 9.6 14.0 10.7 13.7 7.2 10.1 10.2 5.5 5.9 13.1 7.7 10.4 29.0 10.1 6.5 6.6 12.9 10.3 37.1 13.2 12.8 11.0 7.9 8.2 8.7 11.9 16.3 20.8 35.7 19.2 25.0 10.4 9.2 35.2 13.9 18.5 35.2 19.6 30.2 18.3 16.1 28.0 8.8 13.2 27.0 25.8 27.9 16.2 11.1 74.8 21.0 20.4 42.5 11.5 47.6 77.6 9.5 17.3 28.7 16.1 14.8 21.2 58.8 42.8 8.2 15.0 21.6 67.6 60.1 34.0 14.7 61.4 53.7 23.8 59.6 10.6 9.9 97.0 29.2 23.8 27.1 16.8 7.6 10.2 23.9 16.0 24.5 21.9 22.9 31.0 18.5 16.1 19.9 35.2 36.6 15.7 50.8 18.9 46.1 21.0 20.8 20.4 9.3 17.5 16.3 17.8 9.3 16.0 15.5 27.9 16.1 22.7 11.9 20.1 21.7 16.0 18.4 5.5 24.7 18.2 11.7 10.4 9.1 10.1 6.6 13.2 16.3 5.5 3.2 5.5 3.3 5.2 9.1 8.0 11.5 9.6 10.2 8.4 7.1 2.6 4.3 7.7 5.5 6.2 17.3 8.5 13.2 11.7 13.7 115.4 18.8 4.4 6.0 4.8 8.8 14.8 13.6 11.7 6.6 12.8 4.7 5.1 7.6 6.8 4.7 9.9 18.5 11.2 9.2 6.1 5.1 2.5 36.6 7.8 7.6 7.2 3.7 6.1 10.0 11.3 2.5 4.9 10.1 5.1 4.9 13.3 7.3 10.5 8.0 26.2 10.9 6.6 4.9 6.3 41.8 8.3 11.9 13.8 7.7 10.9 8.2 11.8 7.8 KATNBL1 "C15orf29, FLJ22557" ENSG00000134152 "Katanin regulatory subunit B1 like 1" Q9H079 15 34140674-34210096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 128.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062573 Approved Supported "Nucleoplasm,Midbody,Cleavage furrow,Mitotic spindle" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Midbody, Mitotic spindle" "Nucleoplasm, Cleavage furrow" "HPA062573: AB_2684796" "unprognostic (5.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.35e-2)" "unprognostic (2.91e-2)" "unprognostic (2.01e-2)" "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (5.16e-2)" "unprognostic (3.94e-3)" "unprognostic (8.00e-3)" "prognostic unfavorable (4.60e-5)" "unprognostic (2.71e-2)" "unprognostic (7.23e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" 22.0 12.1 16.3 22.9 16.6 16.3 20.8 25.0 20.8 22.5 22.4 19.9 15.9 20.7 19.0 39.9 16.8 15.9 13.4 15.8 14.9 17.0 17.6 18.4 17.6 15.0 13.8 14.4 14.0 14.5 12.1 32.4 16.0 16.9 21.2 31.2 14.6 13.6 13.2 31.4 15.7 25.4 12.9 18.6 17.7 18.0 18.2 15.2 12.5 13.0 20.3 17.8 27.7 25.3 37.1 31.5 49.7 33.4 39.5 39.0 37.0 49.6 30.0 38.7 38.4 17.8 19.9 17.6 31.2 32.2 54.5 47.5 24.9 28.5 45.8 36.9 12.6 31.8 34.6 21.6 27.0 33.9 33.1 23.6 40.8 26.1 51.3 39.7 70.6 45.4 34.3 36.7 53.1 17.6 21.4 27.4 35.8 47.4 25.0 32.3 30.3 16.1 35.9 49.5 28.1 24.8 30.1 21.9 14.7 49.2 27.0 38.8 40.4 51.9 26.7 46.8 39.7 21.5 32.5 37.1 46.5 35.7 38.9 62.8 18.2 29.7 18.4 17.3 23.3 23.9 19.6 18.8 20.7 25.6 21.5 19.2 128.5 13.2 11.5 28.4 17.9 12.0 16.3 16.6 25.0 20.8 15.8 14.9 15.0 13.8 16.0 12.9 18.2 25.3 59.7 38.5 25.2 83.9 41.7 41.3 65.2 60.5 34.7 57.0 42.1 43.1 12.8 24.3 51.6 25.8 52.1 58.6 42.3 30.6 33.2 59.1 75.4 40.5 53.3 47.0 23.9 39.8 104.3 54.5 86.2 38.8 39.3 50.8 44.9 68.7 37.9 20.8 39.1 67.3 96.7 35.6 52.9 27.6 48.8 59.2 31.7 36.2 32.0 64.6 49.9 53.1 27.8 86.0 114.4 105.3 37.4 33.1 41.1 116.8 21.4 41.6 49.6 44.7 59.2 52.2 45.3 47.8 44.3 45.0 54.3 179.5 39.7 31.6 39.1 132.6 KAZN "C1orf196, FLJ43806, KAZRIN, KIAA1026" ENSG00000189337 "Kazrin, periplakin interacting protein" Q674X7 1 13892792-15118043 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 91.5" "Group enriched" "Detected in many" 12 "Excitatory neurons: 1065.9;Inhibitory neurons: 2872.7;Oligodendrocyte precursor cells: 1360.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 23 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "AN3-CA: 85.6;SK-BR-3: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032095, HPA032096" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear speckles, Cytosol" "HPA032095: AB_2674146, HPA032096: AB_10670826" "unprognostic (2.81e-1)" "unprognostic (5.82e-2)" "unprognostic (1.12e-1)" "unprognostic (2.42e-3)" "unprognostic (5.34e-2)" "unprognostic (2.15e-3)" "unprognostic (6.57e-3)" "unprognostic (7.88e-3)" "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (1.10e-1)" "unprognostic (5.55e-2)" "prognostic favorable (1.20e-6)" "unprognostic (3.61e-2)" "unprognostic (7.93e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-2)" 12.6 17.7 27.3 3.0 31.5 0.6 11.4 43.6 33.6 17.0 23.9 5.5 5.1 4.2 12.2 34.9 12.6 7.7 6.9 25.0 24.1 24.9 5.8 16.5 1.0 37.1 32.9 16.7 9.2 29.5 5.1 6.3 32.7 7.5 3.9 12.9 21.4 7.4 1.4 23.5 5.3 3.6 29.2 91.5 5.1 4.5 34.1 1.9 10.3 1.6 5.5 8.9 21.3 47.1 17.7 3.0 18.5 85.6 7.9 8.2 6.3 8.3 6.9 15.0 10.8 4.0 9.3 0.0 21.1 17.8 2.7 6.3 4.3 13.5 7.5 0.5 8.4 10.1 10.2 26.6 5.8 0.0 5.0 11.6 17.7 3.5 2.3 6.8 0.1 2.5 4.2 19.8 12.2 12.8 0.1 1.1 5.1 7.9 2.6 6.0 0.4 10.6 25.5 5.4 9.8 7.1 1.5 46.3 33.0 10.5 2.8 6.7 0.0 12.4 11.6 19.8 10.1 3.3 3.0 0.0 11.6 17.4 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 27.3 31.5 43.6 33.6 25.0 24.1 37.1 32.9 32.7 29.2 34.1 47.1 17.6 3.2 1.8 124.1 0.9 50.3 16.6 9.7 31.3 12.4 23.0 27.9 3.4 4.3 9.1 49.7 8.4 1.5 0.9 12.3 17.6 2.0 6.8 51.4 15.8 19.4 7.1 0.0 1065.9 1.6 8.1 27.0 3.6 16.8 3.8 9.7 31.1 0.1 0.8 0.0 2872.7 5.2 18.3 0.9 11.4 9.1 19.0 1.1 46.2 93.7 0.0 74.2 4.1 1360.7 143.5 1.5 1.6 17.3 0.3 19.4 2.0 12.9 30.3 3.2 6.6 33.5 23.6 0.3 3.2 26.2 90.4 46.4 1.4 41.6 3.5 24.8 KBTBD4 "BKLHD4, FLJ10450, HSPC252" ENSG00000123444 "Kelch repeat and BTB domain containing 4" Q9NVX7 11 47572197-47578976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037792, HPA037793" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Cytosol" "HPA037792: AB_10671633, HPA037793: AB_2675671" "unprognostic (5.52e-2)" "unprognostic (2.23e-1)" "unprognostic (8.36e-3)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "unprognostic (1.21e-1)" "unprognostic (2.09e-1)" "unprognostic (8.73e-3)" "unprognostic (2.78e-1)" "unprognostic (4.04e-2)" "unprognostic (7.22e-2)" "prognostic favorable (2.70e-7)" "unprognostic (4.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.07e-1)" "unprognostic (4.25e-2)" 10.2 13.9 5.8 4.6 6.2 8.7 10.0 7.2 6.2 10.0 6.4 12.8 4.2 13.2 8.8 9.2 10.6 4.6 10.6 5.9 5.8 9.9 8.3 8.3 6.4 5.5 5.7 10.9 8.4 12.4 13.0 4.3 5.6 8.5 6.2 7.4 10.3 6.7 24.3 13.1 10.5 6.7 5.7 10.9 10.4 14.5 5.7 7.9 9.3 11.0 8.4 11.3 8.3 6.0 5.0 11.8 13.0 10.2 7.8 10.6 3.7 9.0 11.8 12.8 11.2 4.0 9.8 9.6 4.8 11.6 9.2 8.5 7.5 13.3 10.9 12.6 10.7 7.2 15.9 5.7 5.8 15.3 14.5 9.6 9.1 5.4 6.9 8.8 13.4 6.7 5.4 7.6 10.2 13.1 11.2 4.6 6.4 14.0 7.6 10.2 17.0 5.4 13.8 11.9 17.2 11.0 7.7 10.4 6.5 4.3 17.4 4.8 10.7 7.9 8.4 12.1 9.0 10.3 20.3 14.2 11.5 4.2 8.8 11.6 4.6 11.7 12.5 3.8 13.8 11.6 9.8 11.4 5.9 10.9 10.6 11.4 8.3 13.5 4.1 2.5 12.8 10.4 5.8 6.2 7.2 6.2 5.9 5.8 5.5 5.7 5.6 5.7 5.7 6.0 6.2 6.4 3.6 3.3 9.6 4.8 6.2 16.4 7.4 14.0 6.9 4.4 0.1 8.6 11.3 11.0 8.4 12.3 9.7 6.9 23.5 13.9 14.5 10.2 5.2 9.0 7.2 9.5 5.7 13.7 7.3 5.8 1.5 4.6 10.8 6.8 7.5 8.8 8.1 13.5 6.6 4.0 20.3 4.1 2.9 18.3 5.0 4.3 1.8 3.7 11.4 24.9 10.3 2.5 4.6 9.0 2.9 9.4 5.8 4.1 6.3 10.9 18.8 12.1 13.1 6.9 6.0 23.7 20.1 4.0 4.5 14.1 10.2 7.6 5.4 4.6 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;lymphoid tissue: 2.3;retina: 4.6" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 264.8;Excitatory neurons: 279.1;Inhibitory neurons: 241.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 1.4;HDLM-2: 1.4;HEK 293: 3.4;SCLC-21H: 2.7" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" 0.1 0.4 1.7 0.0 2.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 2.4 2.2 0.0 0.0 0.0 0.0 1.0 2.6 0.0 0.5 0.0 1.1 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.3 0.0 1.3 2.3 0.4 0.3 1.5 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.0 1.4 2.4 2.2 1.0 2.6 0.4 1.3 1.5 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 17.4 0.0 0.0 0.3 0.0 0.0 1.8 264.8 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 17.9 0.0 279.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 241.2 0.6 0.0 0.0 0.0 6.8 1.2 0.0 0.0 3.7 0.0 0.7 0.0 11.6 4.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.4 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 47.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 79.6;Excitatory neurons: 48.2;Inhibitory neurons: 120.2" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.2;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "HeLa: 1.6;RH-30: 3.7;SCLC-21H: 3.5;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" 0.1 0.8 1.1 0.1 3.3 0.9 0.2 41.0 47.3 0.9 0.0 0.3 0.3 0.3 0.0 0.2 0.1 0.2 0.1 4.5 8.0 0.1 0.2 0.1 0.2 8.8 3.0 0.2 0.4 0.0 2.2 0.0 9.3 0.2 0.0 7.0 0.3 0.0 0.5 0.5 0.3 0.0 1.0 0.2 0.3 1.4 12.3 0.1 0.3 1.2 0.0 0.3 0.5 18.8 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.1 0.2 1.1 0.3 1.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.4 3.7 0.4 0.0 0.2 3.5 2.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 1.0 0.1 0.0 0.2 0.3 0.4 0.2 0.2 0.4 3.2 0.3 0.4 0.3 0.2 0.2 0.2 0.3 0.2 0.0 0.5 0.2 0.2 1.4 0.2 0.3 0.3 0.1 0.1 1.1 3.3 41.0 47.3 4.5 8.0 8.8 3.0 9.3 1.0 12.3 18.8 0.2 0.0 0.0 5.5 1.1 0.0 0.2 0.0 0.0 79.6 0.3 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 9.5 0.2 0.5 0.4 7.7 0.0 48.2 0.2 0.0 0.3 0.0 0.3 0.0 2.8 0.0 0.0 0.0 1.7 120.2 0.0 0.0 0.0 0.0 10.2 0.3 0.2 0.0 7.5 0.6 1.5 0.0 16.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.2 0.5 6.1 5.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 28.9;choroid plexus: 32.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Extravillous trophoblasts: 14.4;Inhibitory neurons: 8.8;Oligodendrocyte precursor cells: 18.1;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 14.3;MCF7: 5.1;T-47d: 6.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" 0.1 0.0 20.6 0.1 28.9 0.0 0.2 0.0 21.5 0.0 32.1 1.2 0.2 0.6 0.0 0.2 0.1 0.1 0.7 28.8 14.7 0.4 0.0 0.3 0.1 0.0 5.3 0.0 0.9 0.3 0.8 0.0 0.0 0.7 0.2 0.2 0.1 0.3 0.0 0.0 0.6 0.0 0.6 0.5 0.3 0.5 12.5 0.3 0.0 0.0 0.0 0.6 0.0 15.8 0.1 14.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 2.1 0.1 1.5 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.1 6.1 0.7 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.9 0.0 21.5 28.8 14.7 0.0 5.3 0.0 0.6 12.5 15.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 0.0 2.0 0.8 1.4 1.4 0.0 0.0 0.0 2.1 0.0 0.1 1.6 0.0 0.0 2.2 0.8 0.3 0.9 1.2 0.0 9.3 0.0 14.4 0.7 0.0 2.0 0.0 0.2 0.0 0.0 0.2 0.0 8.8 0.2 0.0 0.0 0.0 3.4 0.3 0.1 0.0 1.9 0.0 0.3 0.0 18.1 1.4 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 7.7 0.0 0.4 0.3 0.1 KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 8.5;retina: 4.5" "Group enriched" "Detected in some" 16 "Bipolar cells: 62.2;Excitatory neurons: 185.0;Inhibitory neurons: 74.4;Oligodendrocyte precursor cells: 65.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 7.2;RT4: 10.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "Nucleoplasm, Cytosol" "HPA030487: AB_10609995, HPA072351: " "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-2)" "unprognostic (8.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.70e-3)" "unprognostic (3.11e-1)" 0.2 1.0 2.4 0.0 2.1 0.0 0.0 0.0 5.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 1.8 0.0 0.0 0.0 0.0 2.9 3.3 0.0 0.0 0.0 0.3 0.2 3.0 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 8.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.8 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.1 0.0 5.9 4.5 1.8 2.9 3.3 3.0 0.8 8.5 1.2 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 62.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 5.8 0.1 0.2 0.2 0.0 0.0 185.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 74.4 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.8 0.0 0.5 0.0 65.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.6 0.0 0.0 0.1 1.6 1.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 25.5;skeletal muscle: 69.1;tongue: 25.7" "Cell type enriched" "Detected in many" 6 "Horizontal cells: 89.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.3;HeLa: 3.9;PC-3: 4.3;SCLC-21H: 4.8;SiHa: 2.5;SuSa: 5.2;U-2197: 4.2" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (3.81e-3)" "unprognostic (2.69e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (4.91e-2)" "unprognostic (8.12e-2)" "unprognostic (1.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (5.90e-2)" "unprognostic (9.70e-3)" 1.3 1.1 2.9 0.6 2.2 0.4 0.8 25.5 3.3 1.2 0.0 0.9 0.1 0.5 0.6 1.4 2.1 0.4 6.4 1.5 2.9 1.3 0.1 1.9 0.1 4.0 6.0 0.4 0.2 5.5 0.8 0.4 3.1 0.6 0.3 1.3 0.7 0.6 69.1 3.6 0.4 0.6 1.1 1.2 1.1 0.8 10.8 0.1 1.1 25.7 1.0 0.7 0.5 1.4 0.0 0.7 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 4.3 0.0 0.6 1.1 0.0 0.0 4.8 0.2 2.5 0.0 1.1 5.2 0.0 0.0 2.0 0.0 0.3 4.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.2 25.5 3.3 1.5 2.9 4.0 6.0 3.1 1.1 10.8 1.4 1.4 0.0 0.0 0.7 0.0 1.5 0.0 2.3 0.0 2.9 0.0 0.3 14.3 0.0 1.2 1.8 0.0 0.0 0.1 1.1 1.9 0.0 0.5 0.4 0.5 3.4 1.2 0.0 2.8 0.0 0.0 3.4 0.5 1.8 0.0 0.0 6.8 0.1 0.2 89.2 5.7 1.4 4.1 0.0 1.2 0.5 7.5 0.1 0.0 2.8 0.0 10.2 0.0 0.0 0.2 0.0 0.5 4.1 0.0 0.2 0.0 0.8 0.1 1.5 0.0 3.0 0.7 0.6 2.5 0.0 2.3 0.1 0.5 0.0 1.8 0.2 KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 241.6;thyroid gland: 129.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 197.9;Cholangiocytes: 88.6;Proximal tubular cells: 236.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "neutrophil: 395.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 68.7;GAMG: 103.6;HBEC3-KT: 69.6;RPTEC TERT1: 67.5;RT4: 80.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" 8.7 0.5 0.8 20.7 0.7 14.1 2.8 0.9 6.7 12.7 0.5 0.9 1.5 0.5 11.0 8.5 1.2 30.4 0.8 0.8 0.6 241.6 2.8 42.2 1.2 0.9 0.6 0.3 57.8 0.7 0.4 4.6 1.8 2.6 0.4 0.5 25.5 14.6 0.5 3.0 0.7 2.4 0.3 11.7 40.5 1.8 5.4 1.9 129.5 3.0 1.9 25.1 8.1 1.1 1.6 0.0 0.3 0.6 13.7 68.7 0.6 1.0 4.8 0.0 0.0 0.0 0.6 0.2 0.0 7.5 103.6 23.5 0.0 69.6 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.1 21.0 7.2 17.8 3.8 1.5 3.2 0.1 0.2 0.7 31.6 0.0 0.1 0.2 0.0 0.1 0.7 1.5 0.3 0.7 67.5 80.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.4 3.5 0.2 1.7 0.4 0.1 5.6 4.3 0.4 0.3 19.3 0.1 0.0 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.3 395.3 0.0 0.0 0.4 0.0 4.6 0.8 0.7 0.9 6.7 0.8 0.6 0.9 0.6 1.8 0.3 5.4 1.1 2.9 60.9 197.9 0.0 1.1 2.8 10.4 20.7 13.6 0.0 0.5 0.0 1.6 88.6 33.1 31.3 0.0 0.1 0.0 0.0 17.6 27.8 1.9 0.0 0.0 4.6 0.0 0.0 0.3 8.6 0.8 1.5 15.8 0.1 6.3 0.0 0.7 0.4 0.4 0.0 0.1 0.0 2.0 2.9 3.0 2.2 0.6 5.9 1.8 0.0 2.1 0.0 0.0 0.0 0.1 44.7 0.0 0.0 0.1 0.7 0.0 236.9 7.0 0.0 0.0 1.5 0.8 1.1 1.1 16.8 1.6 0.1 1.7 0.1 0.0 9.0 KCNJ18 "KIR2.6, TTPP2" ENSG00000260458 "Potassium inwardly rectifying channel subfamily J member 18" B7U540 17 21692523-21704612 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 7.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 0.8;head and neck cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027021 Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (2.41e-1)" "unprognostic (3.90e-5)" "unprognostic (2.56e-1)" "unprognostic (1.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 7.7;thyroid gland: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 11.0;Exocrine glandular cells: 7.9;granulocytes: 6.3;Microglial cells: 17.8;Smooth muscle cells: 5.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.8" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.8" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 83.8" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: AB_10962838" "unprognostic (5.33e-3)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "unprognostic (4.09e-2)" "unprognostic (4.95e-1)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.77e-11)" "unprognostic (5.89e-2)" "unprognostic (5.36e-1)" "unprognostic (2.82e-1)" "unprognostic (3.86e-3)" 0.5 0.3 0.3 0.4 0.4 1.2 0.8 0.3 0.6 0.7 0.2 0.6 1.9 1.2 0.0 0.3 0.8 2.5 5.8 0.2 0.3 0.1 4.0 7.7 0.7 0.4 0.5 0.2 3.9 0.1 1.8 4.0 0.3 0.6 0.5 0.0 0.7 0.2 0.1 0.1 1.1 1.0 0.2 0.7 2.9 0.2 0.5 1.3 6.5 0.5 1.1 0.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 63.8 0.0 0.3 0.3 0.4 0.3 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.5 0.3 0.0 0.0 2.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 7.9 0.0 1.8 1.1 0.1 6.3 0.0 0.7 0.2 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.9 0.0 17.8 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 KCNK6 "K2p6.1, TWIK-2" ENSG00000099337 "Potassium two pore domain channel subfamily K member 6" Q9Y257 19 38319845-38332076 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 151.3;Urothelial cells: 131.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.2" "Group enriched" "Detected in many" 6 "dendritic cells: 11.4;granulocytes: 26.2;monocytes: 7.2" "Cell line enhanced" "Detected in many" "HEL: 37.6;HMC-1: 40.3;T-47d: 22.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022637, HPA040184" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Actin filaments" "CAB022637: , HPA040184: AB_2676876" "unprognostic (7.98e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.45e-6)" "unprognostic (3.76e-1)" "unprognostic (6.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.08e-2)" "unprognostic (4.31e-1)" "unprognostic (4.91e-1)" "unprognostic (4.10e-3)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.07e-2)" "unprognostic (3.46e-1)" "unprognostic (5.88e-2)" "unprognostic (4.59e-3)" 3.9 2.4 2.9 7.5 2.4 3.9 5.6 3.0 3.3 29.9 2.7 15.4 4.6 24.0 1.5 30.5 15.7 4.5 6.7 2.7 2.2 3.1 3.0 9.4 5.6 2.9 2.3 9.5 12.5 0.6 1.9 7.0 2.9 6.2 9.4 0.8 14.5 2.4 1.5 19.1 6.8 14.3 2.1 15.6 9.5 2.1 2.8 2.5 1.4 0.7 7.9 13.3 18.2 3.7 9.2 3.3 0.5 0.5 5.1 3.3 0.7 7.8 3.8 2.0 2.7 2.6 9.8 0.6 3.5 11.2 2.1 11.7 4.2 17.7 1.3 0.4 0.3 37.6 1.9 0.4 4.7 2.7 40.3 0.8 15.6 2.5 4.8 10.5 5.3 5.8 0.5 2.8 5.7 20.2 2.4 2.3 0.4 19.4 2.1 3.9 0.5 2.7 7.1 0.8 0.5 0.8 0.8 0.8 0.3 1.8 22.8 10.5 5.8 0.5 4.4 4.1 0.4 1.0 0.2 1.0 0.6 13.4 0.3 26.2 6.9 15.8 1.4 6.2 1.2 1.4 2.0 1.9 11.4 1.1 1.7 1.2 5.0 0.6 7.2 3.1 2.6 2.3 2.9 2.4 3.0 3.3 2.7 2.2 2.9 2.3 2.9 2.1 2.8 3.7 8.7 0.0 10.5 0.0 16.0 43.1 50.6 20.6 20.5 3.3 61.2 32.9 12.1 17.2 15.1 7.3 6.2 2.0 18.5 62.4 0.0 19.1 2.8 32.5 58.8 28.3 12.6 17.9 1.1 47.7 4.0 19.2 28.1 84.8 22.2 72.7 151.3 4.3 39.2 0.0 1.7 64.5 2.0 75.7 61.5 1.2 25.7 47.0 5.4 2.8 62.1 1.2 11.3 0.0 0.9 67.2 39.2 20.3 45.6 41.1 37.6 0.4 7.7 5.9 26.3 3.1 9.3 14.8 3.3 48.0 67.2 2.5 14.8 1.5 26.7 131.5 KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lung: 23.5;skeletal muscle: 86.0;tongue: 45.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Enteroendocrine cells: 32.5;Theca cells: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 69.2;RPMI-8226: 28.9;RT4: 48.2;U-266/84: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" 2.9 1.1 2.6 3.8 2.9 0.0 6.2 3.9 4.0 7.8 9.5 12.5 3.7 3.2 2.6 6.0 3.9 5.4 6.6 2.9 4.2 5.0 3.8 23.5 0.6 10.5 7.9 1.0 9.8 2.9 1.2 11.0 12.5 6.5 5.0 0.4 11.2 3.1 86.0 5.6 5.4 3.3 5.3 1.0 9.5 3.9 4.3 1.4 2.3 45.5 2.0 6.8 6.3 4.4 8.5 1.4 0.7 0.0 1.6 0.8 3.8 2.8 8.5 1.7 2.0 0.1 17.1 0.0 0.9 3.0 1.9 2.7 20.7 0.1 1.8 0.0 5.7 0.0 0.2 0.1 8.1 0.2 0.7 0.7 12.9 0.1 1.2 15.5 0.4 3.9 0.4 0.0 1.0 2.2 0.0 0.0 10.2 11.5 0.2 2.4 69.2 28.9 1.8 48.2 20.3 0.7 0.0 5.3 6.1 4.8 2.8 0.0 0.2 2.7 0.0 0.2 21.6 0.1 34.9 0.1 15.2 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 3.9 4.0 2.9 4.2 10.5 7.9 12.5 5.3 4.3 4.4 3.8 28.9 8.2 0.0 0.0 13.9 16.8 6.9 21.1 0.2 11.5 7.0 0.5 18.6 6.8 11.0 0.0 0.6 0.0 10.9 0.0 21.5 0.3 0.9 0.6 5.9 32.5 0.0 0.3 0.4 3.5 12.1 8.2 0.9 1.3 4.3 2.5 5.4 0.5 0.0 16.9 5.6 14.2 0.0 4.5 1.2 1.5 0.4 21.4 1.9 0.7 0.1 0.0 7.1 2.5 2.4 4.9 3.8 1.2 13.6 4.1 5.5 1.7 0.2 6.6 13.5 10.6 0.3 3.4 8.0 5.8 0.8 0.6 30.6 10.3 7.1 KCTD1 C18orf5 ENSG00000134504 "Potassium channel tetramerization domain containing 1" Q719H9 18 26454910-26657401 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 106.4;Distal tubular cells: 117.4;Excitatory neurons: 283.7;Squamous epithelial cells: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.6;HaCaT: 113.5;hTCEpi: 100.6;RPTEC TERT1: 97.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057808, HPA062486" Approved "Nucleoplasm,Nucleoli,Cytokinetic bridge,Centriolar satellite" Yes NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytokinetic bridge, Centriolar satellite" "HPA057808: , HPA062486: " "unprognostic (1.15e-3)" "unprognostic (5.66e-2)" "unprognostic (2.35e-4)" "prognostic unfavorable (2.22e-4)" "unprognostic (3.65e-3)" "unprognostic (7.43e-2)" "unprognostic (2.03e-3)" "unprognostic (6.77e-2)" "unprognostic (2.74e-1)" "unprognostic (1.88e-3)" "unprognostic (5.68e-3)" "unprognostic (1.77e-2)" "prognostic favorable (4.60e-8)" "unprognostic (3.87e-3)" "unprognostic (7.39e-2)" "unprognostic (1.50e-1)" "unprognostic (8.02e-2)" 7.8 16.5 21.7 2.7 41.5 0.6 32.4 14.0 44.3 19.2 9.5 9.7 4.1 14.2 22.6 50.6 50.2 8.4 23.8 31.2 10.3 28.8 3.5 5.5 2.7 9.8 13.6 15.1 7.4 12.0 10.8 11.4 9.2 21.6 10.6 18.4 19.9 22.6 5.1 61.1 3.7 12.5 10.2 3.9 10.3 5.9 13.7 17.6 19.9 6.9 14.3 13.0 36.9 29.6 17.5 55.1 106.6 11.6 61.8 9.7 13.4 14.3 21.5 22.0 21.9 5.1 19.1 2.9 52.2 30.5 18.0 113.5 20.5 30.6 20.6 2.2 8.7 3.1 10.2 8.2 11.1 1.7 4.7 16.7 100.6 6.2 41.4 28.0 21.0 24.1 1.3 1.2 16.0 24.5 16.3 5.2 10.5 57.1 27.1 8.5 5.7 2.3 97.8 25.2 10.3 40.5 20.7 27.5 8.7 61.3 24.1 4.0 11.7 24.4 6.8 4.8 15.0 4.8 4.1 0.4 8.7 11.0 36.8 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 41.5 14.0 44.3 31.2 10.3 9.8 13.6 9.2 10.2 13.7 29.6 3.0 3.2 4.1 80.0 0.7 31.7 55.9 17.2 106.4 5.0 27.3 29.7 13.9 8.6 15.0 25.8 8.4 45.5 0.8 6.2 117.4 8.3 28.0 47.0 7.8 2.9 1.2 0.8 283.7 3.6 7.6 5.5 7.1 42.4 0.0 66.3 2.5 1.7 4.4 21.9 66.1 4.3 20.3 0.8 1.7 12.0 5.3 1.2 23.2 16.9 0.4 21.4 1.0 81.4 42.1 11.8 2.4 3.0 6.6 36.4 0.4 10.7 29.3 5.9 0.0 2.7 6.2 1.8 5.1 109.0 44.5 33.2 1.0 6.3 4.0 51.2 KCTD14 MGC2376 ENSG00000151364 "Potassium channel tetramerization domain containing 14" Q9BQ13 11 78015715-78046191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 13.7;Breast myoepithelial cells: 12.8;Exocrine glandular cells: 17.1;Gastric mucus-secreting cells: 14.3;Intestinal goblet cells: 20.8;Prostatic glandular cells: 14.3;Proximal tubular cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 26.1;Hep G2: 29.0;RPTEC TERT1: 45.9;U-2 OS: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041118, HPA042181" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Vesicles, Cytosol" "HPA041118: AB_10963117, HPA042181: AB_10968059" "unprognostic (7.37e-3)" "unprognostic (4.27e-2)" "unprognostic (7.03e-2)" "unprognostic (6.93e-2)" "unprognostic (1.59e-2)" "unprognostic (2.28e-2)" "unprognostic (2.04e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.96e-5)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (1.05e-4)" "unprognostic (3.19e-1)" "prognostic favorable (6.92e-5)" "unprognostic (2.42e-2)" "unprognostic (2.05e-1)" "prognostic favorable (5.93e-4)" "unprognostic (1.63e-1)" 3.4 23.1 2.0 1.6 2.0 0.1 20.4 5.1 2.9 10.4 3.2 8.1 4.9 3.4 14.3 1.5 11.7 6.7 0.6 2.1 2.1 11.5 10.3 8.2 0.3 1.9 2.3 0.8 27.2 8.3 2.5 1.3 2.2 7.0 11.9 1.6 28.7 19.1 0.2 1.9 5.2 2.1 1.6 0.6 20.8 0.6 2.5 1.3 15.9 0.6 0.5 2.3 1.4 1.7 0.0 3.5 0.6 0.5 1.3 0.8 3.5 1.8 1.6 3.4 8.4 13.5 8.8 0.1 9.3 1.1 0.4 1.0 0.6 26.1 8.9 0.5 13.2 0.0 3.0 29.0 4.9 0.2 0.1 4.0 0.7 13.9 11.0 2.5 1.0 0.2 0.3 0.1 1.4 0.2 0.3 0.8 6.5 0.5 0.5 0.4 0.0 0.0 45.9 3.5 2.3 0.2 0.0 0.2 4.5 0.8 1.4 1.1 0.8 0.2 20.2 0.7 0.4 0.3 0.2 0.2 0.2 0.2 3.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.0 2.0 2.0 5.1 2.9 2.1 2.1 1.9 2.3 2.2 1.6 2.5 1.7 0.6 3.2 10.8 0.0 0.2 0.4 12.2 2.0 2.8 0.4 13.7 12.8 0.0 1.5 4.1 5.5 0.0 0.6 0.3 5.2 3.9 2.6 0.3 2.7 2.0 0.9 4.8 0.0 0.0 17.1 1.3 1.1 14.3 3.7 1.3 0.5 0.0 4.8 0.2 0.0 0.0 20.8 0.0 0.0 0.0 0.0 3.4 0.4 1.8 0.0 0.1 2.1 0.0 0.0 0.0 10.5 6.6 5.3 0.0 14.3 2.2 15.1 0.1 0.0 0.0 0.0 1.8 0.2 0.3 0.7 0.1 0.7 0.3 0.7 8.5 7.4 KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042468, HPA047902" Supported "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: AB_2680205" "unprognostic (4.18e-2)" "unprognostic (3.90e-2)" "prognostic favorable (7.88e-4)" "unprognostic (7.04e-2)" "unprognostic (7.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.20e-2)" "unprognostic (6.01e-2)" "unprognostic (4.33e-1)" "unprognostic (2.43e-2)" "unprognostic (4.49e-3)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (4.97e-3)" 18.4 8.2 4.9 11.5 5.8 21.5 22.3 7.9 6.5 15.4 8.6 21.1 19.6 11.3 13.0 23.8 14.6 13.3 38.3 5.5 5.9 12.8 10.8 13.4 12.2 9.1 7.7 14.2 11.2 11.0 9.8 12.0 10.0 17.4 22.6 12.9 17.5 15.6 29.5 19.0 17.7 14.5 7.8 9.4 12.8 12.9 6.9 14.7 13.7 36.7 14.4 15.6 18.7 6.9 46.4 32.4 34.5 11.9 44.0 58.0 28.2 68.6 61.4 44.1 44.5 23.4 33.2 30.1 28.6 69.0 62.3 30.3 30.6 32.3 52.9 15.4 18.2 35.3 30.2 21.7 53.2 12.3 25.1 44.8 38.5 40.2 33.2 26.9 37.8 29.6 37.8 23.0 50.7 12.4 48.2 21.6 16.8 35.8 17.0 18.6 39.8 11.2 45.0 26.1 8.8 11.4 52.7 23.1 35.8 30.8 17.8 14.2 42.2 48.5 28.2 94.1 37.6 6.6 12.9 39.1 33.9 21.8 35.8 0.7 0.5 1.2 1.0 0.7 1.0 0.6 1.0 1.0 0.3 0.3 0.6 0.9 0.5 0.2 0.9 1.0 1.1 0.4 4.9 5.8 7.9 6.5 5.5 5.9 9.1 7.7 10.0 7.8 6.9 6.9 19.5 32.1 18.5 18.6 8.9 74.4 36.4 26.0 31.9 13.7 20.4 12.7 61.1 5.7 24.2 27.6 25.0 9.4 23.3 53.8 13.7 17.6 6.5 12.8 12.7 16.8 10.2 20.2 14.3 27.2 17.6 32.5 8.2 17.9 20.3 10.9 12.5 9.0 9.3 3.3 12.9 16.0 18.3 9.3 18.5 5.2 30.7 12.9 30.2 36.5 8.5 8.1 18.6 17.1 13.6 36.6 21.6 55.7 17.1 52.6 25.8 10.4 17.4 19.6 6.6 21.6 26.2 35.6 26.4 41.6 54.7 11.2 19.8 14.4 17.7 46.0 KDELR1 "ERD2, ERD2.1, HDEL" ENSG00000105438 "KDEL endoplasmic reticulum protein retention receptor 1" P24390 19 48382575-48391551 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 605.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 856.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017455 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Vesicles, Cytosol" "CAB017455: AB_10615208" "unprognostic (3.10e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.49e-4)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.35e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (7.55e-2)" "unprognostic (4.97e-2)" "unprognostic (3.81e-1)" "unprognostic (2.74e-1)" "unprognostic (3.06e-1)" "unprognostic (1.68e-2)" 109.3 124.4 58.0 61.7 56.5 45.8 106.6 54.5 59.7 132.5 78.1 120.3 132.5 110.0 117.3 107.3 112.2 100.9 96.6 56.1 62.5 119.5 127.2 101.4 53.3 61.1 59.1 165.8 138.9 191.7 116.2 128.7 59.0 102.5 128.5 39.0 137.7 105.0 76.8 103.8 114.5 100.6 56.2 79.5 120.1 93.7 62.9 51.6 121.8 58.4 73.2 102.5 102.4 58.0 216.2 305.3 173.1 184.7 379.7 440.6 126.5 207.4 363.9 247.0 281.0 202.3 238.7 89.1 132.6 456.4 154.4 187.6 211.1 222.2 234.0 72.7 224.5 74.4 99.4 382.2 329.6 84.1 133.4 419.6 268.0 168.5 178.5 387.4 233.0 75.3 131.7 160.9 333.1 173.6 79.4 856.7 126.3 426.8 122.5 112.1 103.4 141.0 316.2 176.3 172.9 134.5 182.1 160.6 113.1 196.7 126.6 102.1 182.6 173.4 142.6 145.3 179.3 451.1 382.0 60.2 110.1 112.4 181.1 10.8 41.0 12.6 18.1 34.7 20.8 17.0 17.6 19.7 30.6 14.3 14.3 16.1 9.9 20.2 30.2 45.4 20.4 18.2 58.0 56.5 54.5 59.7 56.1 62.5 61.1 59.1 59.0 56.2 62.9 58.0 150.8 35.3 54.2 8.5 82.2 75.3 130.6 147.1 124.7 39.4 141.0 154.4 28.8 98.7 110.9 93.8 6.2 231.7 59.5 153.0 56.7 224.1 6.2 72.0 188.8 111.4 145.0 56.8 8.7 169.0 605.5 161.0 120.3 166.3 62.7 149.2 102.8 79.6 180.0 40.4 12.7 379.6 93.6 107.6 73.5 14.2 163.5 103.1 92.5 8.4 102.3 89.8 35.0 10.6 10.6 190.3 199.8 132.0 365.9 161.2 213.8 149.6 49.2 28.1 85.5 87.9 131.6 41.8 69.1 127.7 70.2 387.7 55.4 191.3 202.9 157.6 KDM4A "JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A" ENSG00000066135 "Lysine demethylase 4A" O75164 1 43650149-43705518 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007610 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 56: Intestine - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA007610: AB_1852006" "unprognostic (7.01e-2)" "unprognostic (1.50e-1)" "unprognostic (3.22e-2)" "unprognostic (6.18e-2)" "unprognostic (3.54e-2)" "unprognostic (5.40e-3)" "prognostic unfavorable (1.39e-5)" "unprognostic (4.88e-3)" "unprognostic (1.13e-1)" "unprognostic (5.47e-1)" "unprognostic (2.70e-1)" "unprognostic (7.95e-2)" "unprognostic (2.81e-1)" "unprognostic (2.32e-3)" "unprognostic (2.02e-1)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" 10.6 20.6 10.7 12.2 11.3 12.1 12.8 12.7 12.4 15.1 11.8 18.0 28.0 14.2 13.0 14.4 18.0 11.8 10.0 10.7 9.3 12.7 14.8 14.7 15.6 10.7 10.4 19.7 12.7 19.1 10.9 11.2 10.9 13.7 18.5 19.6 13.3 11.4 11.1 21.8 22.6 14.9 10.0 13.9 14.4 5.7 10.7 21.6 17.3 15.7 18.0 13.7 11.8 11.2 25.1 22.6 36.6 63.6 34.5 32.6 25.3 23.4 26.4 34.7 34.6 26.0 21.7 32.5 23.5 23.4 26.3 25.3 45.1 27.6 35.4 23.2 37.8 46.5 33.7 21.2 32.7 33.4 35.9 35.4 43.2 33.7 42.3 26.6 37.0 27.9 23.5 45.1 25.5 19.6 26.4 28.2 59.9 21.5 23.0 35.0 42.2 23.9 24.3 48.8 32.1 29.1 50.5 34.2 63.3 52.8 20.0 111.5 28.1 20.6 32.8 18.7 31.9 20.7 26.7 29.2 21.3 27.8 39.3 10.2 4.9 9.0 4.4 3.7 4.9 4.3 4.3 3.6 4.1 3.1 2.9 2.6 3.0 4.1 5.2 3.6 4.9 3.5 10.7 11.3 12.7 12.4 10.7 9.3 10.7 10.4 10.9 10.0 10.7 11.2 5.3 9.6 22.3 12.7 14.0 9.2 5.3 8.3 25.6 20.1 8.9 7.5 7.4 8.6 8.2 1.8 37.5 8.5 10.4 19.3 5.9 8.6 9.7 11.2 9.8 9.2 12.0 16.4 21.3 6.7 6.1 9.8 23.4 6.9 13.3 12.0 7.9 13.1 8.9 32.0 17.8 16.6 10.2 9.7 5.5 6.1 12.5 7.9 1.8 5.6 11.6 10.9 13.4 17.6 23.8 10.7 13.5 14.7 14.3 5.4 17.3 6.9 25.4 23.5 6.6 11.1 7.7 0.6 2.9 21.0 4.7 8.1 9.5 13.6 15.4 6.0 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 9.6 8.0 6.7 4.5 7.6 19.4 10.6 7.2 10.6 15.7 6.5 9.1 6.2 14.0 5.1 11.1 14.0 3.4 6.6 6.8 6.9 6.8 10.4 10.8 8.0 7.3 6.8 17.2 10.8 6.4 8.6 3.9 7.3 7.7 4.1 3.8 10.5 3.1 10.4 18.4 13.0 4.1 7.1 14.1 12.5 12.2 7.0 12.9 9.4 6.1 5.3 9.8 15.2 9.9 7.3 5.8 7.0 9.3 5.0 6.8 15.7 4.9 4.2 4.0 4.1 10.4 5.2 4.6 3.2 3.5 10.1 13.9 6.5 5.4 3.9 7.6 10.8 2.4 4.5 5.2 3.7 2.6 13.2 2.6 6.4 8.2 6.6 5.1 4.2 5.3 6.4 10.1 2.4 6.0 6.9 13.6 6.8 4.2 7.4 6.4 7.1 1.4 3.8 9.2 6.2 4.4 18.2 6.8 10.7 14.1 8.5 0.0 3.0 5.4 5.2 5.2 3.6 5.5 8.8 5.6 4.0 3.3 3.3 7.3 1.7 1.5 1.9 3.5 2.1 1.9 2.5 2.8 3.1 1.2 2.5 2.4 2.8 2.8 3.0 1.7 2.2 2.0 6.7 7.6 7.2 10.6 6.8 6.9 7.3 6.8 7.3 7.1 7.0 9.9 23.2 6.4 10.6 92.1 26.0 26.1 14.3 9.4 38.1 7.7 16.8 12.1 12.8 12.8 10.9 7.3 14.6 4.5 26.1 24.6 0.0 8.4 1.5 26.4 25.5 13.1 13.1 16.8 88.3 7.5 7.9 14.2 23.0 39.7 2.5 27.3 6.4 17.6 7.0 25.2 74.0 14.0 6.1 9.1 13.8 2.0 6.5 19.9 10.6 116.2 12.6 6.8 6.2 118.1 264.6 9.1 17.4 7.2 31.4 14.2 22.6 3.7 8.9 9.7 6.6 20.9 17.0 14.1 12.5 29.3 26.3 10.9 27.4 10.6 13.1 17.1 KEAP1 "INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454" ENSG00000079999 "Kelch like ECH associated protein 1" Q14145 19 10486125-10503558 "Cancer-related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005558, CAB025337" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" Cytosol "CAB025337: , HPA005558: AB_1079175" "unprognostic (1.98e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-2)" "unprognostic (2.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-3)" "unprognostic (2.04e-1)" "unprognostic (9.99e-2)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.06e-1)" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" 31.3 41.2 54.8 20.5 61.6 20.4 30.3 61.8 60.9 32.7 49.7 37.6 26.5 31.3 22.2 55.4 28.9 24.3 60.7 53.2 59.4 32.5 60.9 25.3 23.2 61.4 60.5 25.3 32.8 24.3 30.0 17.0 60.3 36.8 16.5 16.4 34.7 24.9 178.2 38.7 27.5 18.7 58.8 32.2 33.2 20.5 59.6 23.0 35.6 75.7 18.5 41.4 36.3 68.4 58.0 102.8 27.2 35.1 55.8 45.4 30.3 48.1 35.9 46.6 41.6 73.7 54.2 82.9 122.9 53.3 34.8 49.7 55.6 36.9 23.7 78.3 61.7 126.3 29.9 87.9 54.5 65.4 63.9 50.0 51.0 53.5 25.1 39.1 46.3 23.7 79.1 135.4 41.6 79.9 46.1 177.8 80.8 54.2 88.6 84.6 34.8 95.1 30.4 67.4 75.3 40.4 66.8 42.4 42.1 23.9 37.8 82.3 56.5 72.9 41.0 86.0 57.0 86.8 113.0 81.1 58.0 78.5 56.0 36.4 37.9 41.4 55.3 33.8 53.1 26.3 38.5 52.0 45.4 11.7 23.6 33.7 20.9 42.5 34.6 31.4 50.2 41.8 54.8 61.6 61.8 60.9 53.2 59.4 61.4 60.5 60.3 58.8 59.6 68.4 18.3 28.9 20.8 5.5 13.8 21.9 24.4 40.3 27.9 21.5 15.7 11.4 24.0 21.5 25.4 11.0 8.4 27.3 11.6 33.2 13.7 32.8 27.5 13.4 17.1 27.8 26.9 45.2 5.3 36.3 25.2 23.5 18.8 13.3 12.0 22.8 35.3 34.4 29.0 26.9 5.9 21.4 40.7 15.1 13.4 43.9 29.2 16.1 10.6 3.7 41.8 43.0 7.2 11.6 18.3 29.8 27.1 25.9 26.6 33.3 36.8 24.9 17.2 13.9 13.1 17.7 22.4 21.2 16.6 34.7 22.0 26.8 20.1 29.6 31.5 24.8 KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 56.3;testis: 32.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 79.7;Oligodendrocytes: 30.1;Squamous epithelial cells: 16.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HEL: 31.7;K-562: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 1.8 0.8 2.7 56.3 0.3 1.7 2.2 0.9 1.4 0.1 0.0 0.2 0.0 0.8 0.5 0.0 0.3 2.0 1.5 0.6 0.3 0.5 10.6 2.5 2.2 0.2 0.2 0.0 0.2 0.4 2.4 0.3 0.0 0.1 0.6 0.1 0.2 0.1 0.9 0.0 1.9 4.9 0.2 32.3 2.4 1.3 0.3 0.0 6.7 0.1 0.4 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 31.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.5 0.1 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 1.7 2.2 2.0 1.5 2.5 2.2 2.4 1.9 2.4 2.8 0.2 0.0 0.0 0.3 0.0 0.0 1.3 0.2 4.0 0.0 0.3 0.1 0.4 0.0 1.4 3.7 0.0 0.1 0.1 0.0 1.9 0.3 2.4 0.2 0.1 0.1 0.0 79.7 3.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 1.4 0.2 16.8 0.0 0.1 0.0 0.0 0.0 0.9 KIAA0895 ENSG00000164542 KIAA0895 Q8NCT3 7 36324152-36390125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 22.3" "Cell type enhanced" "Detected in many" "Early spermatids: 87.9;Endometrial ciliated cells: 41.8;Late spermatids: 65.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021036, HPA061066" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA021036: AB_2670571, HPA061066: AB_2684423" "unprognostic (4.94e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-1)" "unprognostic (1.39e-1)" "unprognostic (8.85e-2)" "unprognostic (1.15e-3)" "unprognostic (3.79e-3)" "unprognostic (3.43e-1)" "unprognostic (3.74e-1)" "unprognostic (4.71e-3)" "unprognostic (1.46e-1)" "unprognostic (3.49e-1)" "unprognostic (4.51e-2)" "unprognostic (6.68e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-2)" "unprognostic (5.24e-2)" 1.1 8.1 5.3 0.7 5.8 2.4 3.7 14.2 5.2 2.3 10.5 2.5 1.8 3.0 6.2 2.3 5.8 3.1 1.7 5.3 8.7 9.2 5.5 3.0 0.2 4.1 5.0 8.6 9.1 11.6 6.3 1.2 3.9 2.9 1.3 15.0 2.8 2.6 1.5 5.8 1.1 2.9 3.7 0.6 11.1 22.3 6.0 3.2 3.6 1.4 0.4 1.3 1.1 5.0 10.7 6.3 13.2 12.4 0.4 0.3 2.9 2.8 3.3 6.5 7.5 2.8 5.5 0.1 3.0 0.7 11.0 6.1 18.1 5.6 5.4 0.9 10.1 0.2 9.7 2.5 2.3 1.9 0.4 1.5 9.5 6.0 7.0 7.7 0.2 5.8 4.4 0.2 0.6 3.8 6.0 4.0 0.6 2.6 1.5 2.2 0.5 0.0 13.8 1.3 38.1 13.6 4.8 12.5 4.0 9.0 11.8 1.5 0.0 0.8 3.2 1.8 4.2 6.2 14.6 0.1 2.4 0.5 2.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.3 5.8 14.2 5.2 5.3 8.7 4.1 5.0 3.9 3.7 6.0 5.0 1.5 6.4 2.7 7.5 1.4 9.7 5.1 3.5 17.6 17.8 13.3 8.1 3.7 5.7 3.7 3.7 27.1 2.3 0.9 0.9 5.9 5.0 87.9 41.8 2.2 1.6 8.4 0.8 22.4 2.9 1.2 2.1 11.2 13.3 1.3 8.3 0.4 5.6 0.5 11.8 25.9 1.5 0.0 0.0 0.4 65.4 2.8 0.4 3.6 1.0 0.1 5.7 0.0 12.1 13.1 3.9 1.7 0.4 3.2 3.0 0.2 10.0 25.9 16.3 6.6 5.7 2.1 28.8 11.9 4.7 8.7 0.7 1.2 7.6 1.6 2.0 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 KIAA1328 ENSG00000150477 KIAA1328 Q86T90 18 36829106-37232172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.8;Alveolar cells type 2: 228.3;Inhibitory neurons: 113.9;Oligodendrocyte precursor cells: 117.6;Oligodendrocytes: 178.0;Respiratory ciliated cells: 122.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040946 Approved Approved "Nuclear speckles,Vesicles,Lipid droplets" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Vesicles, Lipid droplets" "HPA040946: AB_10794998" "unprognostic (3.66e-2)" "unprognostic (5.37e-4)" "unprognostic (2.76e-2)" "unprognostic (1.55e-3)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (2.46e-2)" "unprognostic (1.51e-3)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (3.18e-3)" "unprognostic (4.85e-2)" "unprognostic (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (2.25e-2)" "unprognostic (3.36e-2)" "unprognostic (2.64e-3)" 6.9 7.1 24.6 7.7 33.8 22.0 5.7 54.3 62.5 5.0 10.1 6.2 9.0 9.5 9.0 6.6 6.1 7.2 6.6 27.2 13.9 7.2 7.0 7.3 7.5 5.5 1.5 13.7 5.3 5.1 2.8 8.3 12.5 7.6 5.5 37.9 9.4 3.9 11.0 13.6 9.4 5.5 0.6 8.3 9.0 16.8 12.6 4.0 7.0 4.1 4.6 4.6 3.6 75.8 26.2 7.4 11.2 13.5 3.8 5.8 10.5 10.7 4.0 5.1 3.4 12.9 16.4 18.1 32.8 4.1 8.6 11.7 4.2 4.7 6.4 15.3 5.0 22.9 24.6 9.3 3.6 16.0 11.9 5.4 5.8 5.6 5.0 5.5 4.4 10.9 18.1 40.7 5.0 23.0 10.6 10.6 25.0 9.6 11.4 14.0 11.9 12.8 4.2 22.2 11.7 13.5 12.8 15.9 6.7 20.4 23.3 8.3 13.8 22.4 29.5 13.3 11.2 32.2 43.8 14.4 11.0 11.3 15.4 23.8 6.7 9.9 8.2 5.0 9.8 7.4 7.2 7.0 3.2 11.4 9.3 7.5 13.2 7.4 8.0 5.5 9.4 4.0 24.6 33.8 54.3 62.5 27.2 13.9 5.5 1.5 12.5 0.6 12.6 75.8 10.9 230.8 228.3 85.5 13.3 5.7 7.9 7.0 6.8 36.1 6.5 7.1 6.0 7.2 106.8 5.5 20.9 8.8 6.5 1.7 5.9 7.6 51.9 6.8 10.5 18.2 3.0 5.5 83.8 5.8 7.8 23.9 5.1 6.9 107.9 13.5 9.7 3.0 6.6 16.8 113.9 3.2 2.0 4.4 4.6 13.0 9.3 18.3 7.2 94.6 5.0 10.1 19.6 117.6 178.0 6.3 3.7 7.9 8.0 3.6 4.4 4.4 122.7 30.9 0.0 14.3 11.0 45.3 19.6 6.6 7.0 3.8 20.6 11.5 4.5 5.0 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 63.3;Microglial cells: 67.5;Oligodendrocytes: 135.6" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 75.6;ASC diff: 11.3;ASC TERT1: 16.9;WM-115: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" 5.6 2.1 18.4 6.0 87.7 0.5 3.4 39.2 42.2 13.1 0.0 9.0 2.4 14.6 6.4 5.1 8.7 16.2 11.4 29.0 64.1 4.1 1.2 2.5 5.0 59.2 62.3 13.6 0.9 0.1 2.2 0.1 54.7 6.6 4.2 0.5 5.8 7.3 0.6 1.4 4.2 14.7 18.3 2.7 3.6 2.6 75.3 8.3 2.0 1.7 4.7 5.2 4.8 105.0 3.0 0.3 75.6 0.1 11.3 16.9 0.0 7.6 4.3 0.0 0.0 0.3 2.2 0.0 0.3 2.4 2.5 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.3 0.0 2.2 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 1.4 0.0 0.0 0.0 0.2 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 87.7 39.2 42.2 29.0 64.1 59.2 62.3 54.7 18.3 75.3 105.0 0.1 0.0 0.0 63.3 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 2.5 0.2 0.0 0.0 0.8 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.4 1.1 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.9 3.7 0.2 1.8 67.5 0.0 0.0 0.0 19.6 135.6 0.6 0.0 7.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 1.1 1.2 0.3 0.3 0.2 0.3 0.0 0.0 0.4 0.0 0.0 KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 Q5HYC2 9 5881596-6008482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002109 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytosol" Nucleoplasm "HPA002109: AB_1078071" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.52e-1)" "unprognostic (5.97e-3)" "unprognostic (1.61e-1)" "unprognostic (8.74e-2)" "unprognostic (6.86e-2)" "unprognostic (9.19e-2)" "unprognostic (8.41e-3)" "unprognostic (6.49e-2)" "unprognostic (1.52e-1)" "prognostic favorable (8.34e-4)" "unprognostic (2.41e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" 6.8 5.1 13.5 5.6 17.2 6.4 6.2 24.1 11.7 7.8 25.1 6.4 4.8 7.9 5.8 6.1 6.4 5.7 5.7 9.9 12.1 6.1 4.9 5.9 6.7 11.6 13.3 10.2 5.2 8.6 6.2 6.9 11.9 6.2 5.0 10.4 6.1 5.4 9.5 8.2 5.6 6.3 10.3 8.1 6.5 11.5 12.6 8.3 8.4 9.5 5.9 6.2 7.1 17.0 7.1 3.5 7.2 4.6 5.4 8.5 3.2 4.6 6.8 4.4 4.0 2.3 4.0 8.8 1.7 5.8 5.5 3.5 4.2 3.9 6.5 19.2 3.0 26.5 8.4 3.7 4.2 9.4 11.6 5.3 5.0 3.9 6.4 8.3 6.9 5.7 2.8 16.2 5.5 2.2 5.1 17.2 4.0 4.1 2.8 5.3 4.6 4.5 4.8 4.9 9.3 5.3 4.3 4.0 3.7 4.9 4.1 12.6 7.8 8.4 4.7 4.2 5.3 11.1 9.5 8.8 4.3 4.3 2.3 5.0 2.3 7.0 4.2 1.9 4.8 5.9 4.1 3.8 0.9 3.8 4.5 4.8 6.0 4.8 4.5 2.9 2.6 0.8 13.5 17.2 24.1 11.7 9.9 12.1 11.6 13.3 11.9 10.3 12.6 17.0 47.8 44.8 34.0 99.9 40.3 44.6 29.9 21.4 37.5 89.0 33.5 25.5 53.7 42.9 22.1 38.6 79.2 17.1 51.9 31.0 7.9 18.2 33.0 28.3 40.9 39.7 38.5 18.7 97.8 13.4 10.6 33.2 31.1 46.7 20.2 43.5 29.3 18.7 16.9 45.4 119.1 34.7 16.2 25.5 28.8 17.2 70.5 31.9 23.2 113.4 55.1 47.7 95.8 116.1 170.1 18.4 29.1 76.3 35.4 34.4 30.1 11.9 18.2 81.5 46.0 45.8 40.1 127.7 121.2 38.3 52.4 30.0 45.1 38.7 28.5 42.0 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.4;Enteroendocrine cells: 23.8;Hepatic stellate cells: 15.4;Intestinal goblet cells: 14.1;Plasma cells: 15.6;Respiratory ciliated cells: 57.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Cell line enriched" "Detected in single" 9 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" 1.4 0.1 7.5 0.4 10.3 0.2 1.2 4.0 11.4 2.2 3.5 1.7 3.0 0.3 0.0 0.5 12.0 0.4 0.3 7.2 7.4 0.2 0.9 1.9 0.1 7.5 8.0 0.2 1.1 0.0 0.3 0.0 5.9 0.9 0.6 0.1 1.0 0.2 0.4 0.6 2.3 0.4 6.2 13.5 0.7 0.6 7.7 1.0 1.9 0.6 0.1 1.6 1.5 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.4 7.5 10.3 4.0 11.4 7.2 7.4 7.5 8.0 5.9 6.2 7.7 16.7 1.3 0.0 0.0 2.0 1.3 0.0 0.4 2.5 0.0 1.1 0.1 0.0 1.6 0.0 6.3 0.0 0.0 0.0 3.5 0.8 0.0 0.0 0.5 44.4 0.2 4.2 23.8 0.4 0.0 0.0 3.1 1.0 1.1 0.7 0.0 0.0 15.4 0.1 0.1 0.0 0.1 14.1 4.1 0.6 1.6 0.3 0.0 0.3 3.6 0.0 0.1 5.7 3.1 4.0 3.7 0.0 0.1 0.0 15.6 0.3 0.2 0.0 57.6 0.3 0.0 1.8 1.3 0.2 1.6 0.0 0.1 0.0 2.5 0.2 1.9 0.2 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.2;Erythroid cells: 42.3;Extravillous trophoblasts: 32.4;Granulosa cells: 22.4;Spermatocytes: 70.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.0 1.5 0.3 5.7 0.2 21.6 1.4 0.2 0.3 1.5 1.4 4.1 3.9 2.0 0.1 5.3 0.9 1.3 0.6 0.3 0.2 4.6 0.5 1.5 7.9 0.2 0.3 0.7 0.5 0.4 0.1 6.4 0.3 0.9 5.0 0.2 1.1 1.2 0.1 3.7 3.8 4.2 0.2 2.2 2.0 10.6 0.3 15.9 0.3 0.2 9.8 1.8 2.1 0.2 100.7 81.5 64.2 59.0 3.7 7.3 36.3 105.3 57.0 154.8 120.6 50.2 72.4 56.8 31.4 53.1 78.6 110.5 121.6 39.5 158.7 52.9 60.2 55.3 78.8 30.7 2.1 55.6 48.3 3.3 4.2 71.8 60.5 19.4 52.0 46.9 36.0 70.2 95.4 44.1 31.2 28.2 71.6 35.5 33.2 37.0 133.8 31.2 39.3 49.7 32.5 25.3 120.4 51.9 44.9 74.5 50.6 25.3 34.5 90.0 120.8 62.0 157.6 26.3 74.3 48.4 31.5 72.2 78.0 0.0 1.2 4.6 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.2 0.4 0.0 0.5 0.0 2.3 1.9 3.7 4.2 0.0 0.2 1.8 2.8 0.8 5.7 4.7 7.3 2.1 24.2 1.4 3.3 3.9 1.8 13.3 13.1 3.6 2.2 1.8 42.3 1.8 0.0 32.4 5.8 3.6 8.7 2.5 22.4 3.9 0.3 8.1 0.0 1.0 3.1 0.0 2.8 3.4 4.8 0.9 3.2 0.0 1.0 8.1 0.2 0.0 0.0 0.2 0.4 0.4 1.9 6.8 1.6 0.8 0.9 3.6 0.1 6.6 0.4 8.2 70.8 20.9 11.3 1.0 2.5 4.2 3.6 8.6 3.3 KIF26A "DKFZP434N178, KIAA1236" ENSG00000066735 "Kinesin family member 26A" Q9ULI4 14 104138723-104180894 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 22.4;Endothelial cells: 11.9;Enteroendocrine cells: 7.7;Hepatic stellate cells: 13.9;Horizontal cells: 18.5;Spermatogonia: 8.1" "Group enriched" "Detected in many" 5 "stomach cancer: 3.8;testis cancer: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 30.6;MCF7: 24.9;NTERA-2: 20.8;REH: 18.8;SCLC-21H: 19.2;SH-SY5Y: 39.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046882, HPA060346" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046882: AB_2679856, HPA060346: AB_2684259" "unprognostic (3.01e-1)" "unprognostic (3.20e-1)" "unprognostic (3.95e-1)" "unprognostic (1.77e-2)" "unprognostic (2.79e-1)" "unprognostic (1.12e-1)" "unprognostic (5.49e-3)" "unprognostic (1.69e-1)" "unprognostic (1.21e-2)" "unprognostic (3.31e-3)" "unprognostic (5.24e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.78e-4)" "unprognostic (7.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.12e-2)" "unprognostic (4.68e-3)" 5.0 2.3 2.1 0.7 1.3 2.0 4.6 0.5 1.5 5.0 3.0 2.6 0.4 2.4 0.2 1.4 2.6 0.4 5.7 0.8 1.4 3.8 0.6 2.2 0.3 1.3 1.3 4.1 5.7 0.3 2.9 1.8 1.4 0.8 0.4 0.1 1.0 0.8 2.9 2.8 1.9 0.4 0.9 4.2 1.8 2.8 1.8 0.2 1.5 1.0 0.1 2.0 2.1 0.5 0.0 1.7 1.0 3.9 0.0 0.0 6.7 0.3 0.0 0.0 0.0 3.1 0.0 0.0 5.3 0.0 0.7 2.5 3.1 0.0 0.0 0.0 4.9 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 6.7 0.0 0.0 0.0 24.9 0.0 0.0 20.8 0.2 2.0 18.8 7.9 2.0 0.0 0.0 19.2 39.3 4.4 0.6 0.0 2.5 0.4 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.5 1.5 0.8 1.4 1.3 1.3 1.4 0.9 1.8 0.5 22.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.3 0.1 3.2 0.0 0.0 1.8 0.0 1.0 0.0 1.3 1.9 0.7 0.4 0.2 4.4 11.9 7.7 4.8 0.5 0.2 0.8 2.1 0.0 0.2 0.0 0.4 13.9 0.2 2.6 18.5 0.7 2.6 0.0 0.3 1.1 0.1 0.0 0.1 1.8 3.7 0.0 0.2 0.0 0.0 0.1 0.2 1.0 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.7 0.7 0.2 8.1 1.2 1.7 0.4 0.1 0.3 2.8 0.0 KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004715, HPA004716" Approved Enhanced Nucleoplasm,Nucleoli,Centrosome Yes No 300000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nucleoli, Centrosome" "HPA004715: AB_2667215, HPA004716: AB_1079211" "unprognostic (2.40e-2)" "unprognostic (3.43e-1)" "prognostic favorable (1.70e-4)" "unprognostic (2.74e-2)" "unprognostic (1.43e-1)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (3.17e-6)" "unprognostic (8.77e-3)" "unprognostic (4.69e-2)" "unprognostic (9.10e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (3.53e-2)" "unprognostic (2.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.58e-1)" 11.9 7.7 15.6 23.2 20.7 12.8 10.8 15.5 17.7 19.5 0.0 13.8 11.5 12.0 6.3 12.5 17.6 12.9 6.2 17.4 23.0 8.0 5.3 9.8 32.8 17.9 17.5 12.9 10.2 12.3 8.5 16.9 18.4 9.9 14.7 42.7 6.9 11.4 4.8 5.9 15.9 13.1 14.6 18.4 9.6 49.1 16.1 43.6 12.6 6.8 28.9 20.2 7.2 28.0 47.3 46.9 81.4 67.3 28.8 39.6 65.2 51.2 38.5 54.6 67.5 53.1 49.6 111.9 53.3 41.9 67.2 29.1 61.3 37.7 72.5 116.8 44.2 113.8 41.2 27.8 34.7 65.3 42.9 30.5 26.6 50.1 47.5 33.1 49.1 66.5 86.6 66.7 46.9 36.1 104.4 33.1 42.6 12.0 31.9 78.3 59.6 65.3 25.4 55.4 68.0 55.9 67.0 27.9 34.7 55.3 37.6 38.5 39.8 31.9 52.2 40.5 51.3 64.8 94.9 114.1 36.4 74.5 39.8 10.4 4.6 4.7 29.2 5.0 35.3 13.5 29.8 32.7 6.2 10.5 26.3 29.0 7.8 23.2 3.3 9.6 42.3 17.7 15.6 20.7 15.5 17.7 17.4 23.0 17.9 17.5 18.4 14.6 16.1 28.0 30.8 16.0 14.1 54.5 44.1 16.8 41.4 20.1 39.3 45.5 17.9 23.9 9.4 4.3 20.5 20.2 104.3 20.3 73.4 23.1 13.7 37.5 113.8 103.3 47.2 21.4 21.0 42.3 56.7 30.9 22.6 28.2 20.4 43.4 17.7 25.6 19.6 4.4 15.4 52.2 64.5 7.9 14.2 12.9 22.1 130.7 13.1 83.6 12.4 26.2 104.9 28.0 76.2 119.6 156.0 26.6 26.1 13.2 47.8 42.7 13.5 18.7 49.2 92.9 26.3 33.1 25.4 118.9 42.8 34.3 9.5 43.9 77.9 48.9 11.0 56.1 KIF2B ENSG00000141200 "Kinesin family member 2B" Q8N4N8 17 53822927-53825193 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 508 "testis: 75.3" "Group enriched" "Detected in some" 68 "Early spermatids: 744.0;Late spermatids: 623.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023081, HPA023103, HPA024795" Uncertain Supported "Nucleoli,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "Microtubules, Cytokinetic bridge, Mitotic spindle" Nucleoli "HPA023081: AB_10600082, HPA023103: AB_10611254, HPA024795: AB_10602197" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 744.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 623.2 6.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 10.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 33.0;lymphoid tissue: 37.4;testis: 76.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 0.7 0.8 0.7 7.0 0.7 33.0 1.6 2.3 0.7 1.8 1.1 6.2 5.5 1.8 0.7 7.3 0.9 1.3 1.3 0.6 1.1 0.8 0.7 1.3 16.4 1.1 0.9 0.6 0.5 1.3 0.4 5.4 1.4 0.8 7.6 0.8 1.3 0.7 0.9 6.0 5.1 3.2 0.9 3.7 3.5 76.5 0.8 37.4 1.1 0.7 19.2 2.1 2.7 0.8 119.7 45.8 99.6 79.8 5.3 11.6 66.6 86.9 62.1 175.0 151.3 77.6 84.2 136.2 41.3 43.2 121.7 55.2 102.8 59.6 158.2 89.1 44.4 162.1 83.3 65.5 0.6 121.5 71.8 2.7 5.8 125.0 60.3 16.5 57.6 95.4 130.4 113.1 112.4 46.5 127.5 72.9 97.1 58.4 56.5 101.1 149.3 86.4 29.6 42.8 68.3 48.5 116.1 81.6 71.5 71.9 47.2 90.7 34.7 62.9 124.2 69.0 155.6 59.4 65.0 195.3 40.3 115.4 123.9 0.0 0.0 0.0 0.9 0.0 0.0 0.6 1.7 1.2 0.1 0.1 0.3 0.2 0.0 2.0 0.1 0.8 2.9 0.5 0.7 0.7 2.3 0.7 0.6 1.1 1.1 0.9 1.4 0.9 0.8 0.8 0.1 0.0 0.5 1.6 1.3 1.8 0.5 2.4 0.0 1.0 0.9 0.9 1.6 0.0 1.7 1.8 2.1 12.2 1.9 2.9 1.9 0.3 461.1 1.2 1.4 1.6 0.0 34.5 0.8 0.4 23.4 3.2 3.1 2.1 0.0 13.0 2.9 0.2 9.2 0.0 1.0 3.5 0.0 1.9 1.5 1860.6 9.3 3.4 0.0 1.0 4.3 0.4 0.0 0.5 0.2 0.1 0.2 6.8 7.8 0.8 0.3 0.2 0.3 0.2 6.6 0.8 3.4 60.6 36.8 4.6 0.4 3.7 2.7 0.8 7.4 0.7 KIF3A "FLA10, KLP-20" ENSG00000131437 "Kinesin family member 3A" Q9Y496 5 132692628-132737638 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.3;retina: 33.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.7;Horizontal cells: 185.1;Inhibitory neurons: 157.0;Spermatocytes: 147.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 68.2" "Lineage enriched" "Detected in all" 10 "granulocytes: 68.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037085 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Intermediate filaments, Cytosol" "CAB037085: AB_477147" "unprognostic (8.22e-3)" "unprognostic (2.58e-1)" "unprognostic (2.29e-3)" "unprognostic (3.59e-2)" "unprognostic (2.51e-1)" "unprognostic (3.80e-1)" "unprognostic (8.21e-4)" "unprognostic (1.30e-1)" "unprognostic (4.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-2)" "unprognostic (7.64e-2)" "unprognostic (6.08e-3)" "unprognostic (8.62e-2)" "unprognostic (1.92e-1)" "unprognostic (1.17e-1)" "unprognostic (1.23e-1)" 2.6 8.0 14.3 3.8 15.2 1.6 5.0 9.7 26.3 4.4 0.0 3.4 2.5 4.7 5.0 3.3 7.0 4.0 4.6 16.5 16.7 5.8 1.4 4.5 3.9 12.6 13.1 5.1 2.7 11.8 11.3 3.2 17.6 5.1 2.6 33.9 2.8 4.8 2.5 4.0 2.0 4.5 1.3 2.8 3.7 21.5 8.2 6.0 5.4 3.1 3.7 3.8 3.0 13.8 10.6 12.6 11.4 20.8 7.7 7.8 9.4 8.9 7.0 8.2 10.9 13.0 8.0 29.7 11.6 10.4 24.8 7.2 9.6 17.6 17.2 8.6 10.2 4.3 6.9 4.7 7.9 5.3 11.4 5.8 8.6 12.1 14.0 11.4 10.4 18.8 4.8 15.3 10.1 7.9 34.5 4.2 5.5 3.8 4.8 8.8 9.2 3.2 8.4 9.4 36.2 11.9 12.0 4.3 14.4 18.6 12.8 1.6 10.9 10.1 15.9 7.3 10.6 11.5 19.6 16.4 12.9 4.4 11.1 68.2 0.6 1.9 6.3 1.5 6.9 6.7 6.5 6.1 1.3 4.0 6.4 7.0 0.6 4.8 2.0 1.2 5.4 2.0 14.3 15.2 9.7 26.3 16.5 16.7 12.6 13.1 17.6 1.3 8.2 13.8 10.9 54.5 38.0 65.3 12.0 13.6 15.6 25.5 12.5 76.5 13.7 18.7 29.9 11.5 31.7 38.6 125.1 14.6 18.4 0.8 29.4 20.5 86.2 69.7 20.4 11.3 19.8 3.4 178.7 12.9 11.5 16.8 5.6 23.7 13.9 24.6 13.2 2.4 6.2 185.1 157.0 3.8 54.9 3.5 7.7 25.0 16.4 4.8 42.7 21.5 5.4 47.0 5.2 122.6 100.7 12.4 4.6 24.5 14.4 7.6 1.1 10.8 121.0 99.6 13.1 23.8 40.5 147.1 102.6 9.0 15.9 9.9 23.6 27.7 2.1 6.0 KIF3C ENSG00000084731 "Kinesin family member 3C" O14782 2 25926598-25982749 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 75.5;retina: 19.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.5;Horizontal cells: 42.1;Inhibitory neurons: 45.9;Oligodendrocyte precursor cells: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035755 Approved "Nuclear membrane,Nuclear bodies,Intermediate filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nuclear bodies, Intermediate filaments" "Nuclear membrane" "HPA035755: AB_10602242" "unprognostic (3.95e-1)" "unprognostic (1.40e-2)" "unprognostic (7.85e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (2.75e-1)" "unprognostic (4.69e-2)" "unprognostic (3.96e-4)" "unprognostic (1.53e-2)" "prognostic favorable (1.22e-4)" "unprognostic (2.03e-1)" "unprognostic (2.20e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.90e-2)" "unprognostic (3.54e-1)" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" 3.1 6.8 28.4 2.3 40.2 1.5 2.9 6.9 75.5 4.0 0.0 5.4 1.3 3.6 1.7 2.2 2.7 3.6 2.9 46.1 18.6 1.6 0.7 2.0 1.2 37.5 10.9 6.8 1.4 3.7 11.7 2.1 32.7 2.9 1.7 19.6 2.2 3.8 1.8 2.5 2.5 4.2 0.0 1.6 2.3 2.3 13.8 2.6 3.0 2.5 1.1 2.7 3.7 37.8 25.7 38.1 19.9 15.4 11.4 13.1 15.9 13.1 6.4 7.7 8.7 6.8 3.8 0.0 10.6 11.9 24.1 2.7 15.2 7.8 5.2 4.5 7.3 9.3 2.6 14.0 6.7 2.3 7.7 9.6 2.3 24.2 4.8 29.6 25.8 7.3 3.3 3.2 8.3 1.8 6.7 3.2 20.5 0.7 11.1 10.4 9.9 1.7 17.7 6.2 24.2 54.4 5.2 2.2 27.3 16.4 0.8 3.1 20.6 13.4 13.7 6.1 12.9 0.8 4.6 3.1 30.4 12.5 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.1 0.1 0.5 0.2 0.0 0.0 0.4 0.3 28.4 40.2 6.9 75.5 46.1 18.6 37.5 10.9 32.7 0.0 13.8 37.8 1.9 0.0 0.0 9.4 0.2 0.5 1.6 1.5 1.2 16.7 2.0 2.4 3.5 2.8 1.1 0.0 6.2 0.6 2.1 0.1 0.0 8.4 3.4 1.0 2.1 5.6 3.0 0.0 53.5 1.4 4.2 2.6 0.5 1.4 7.0 8.8 7.9 0.1 3.5 42.1 45.9 0.3 2.0 4.6 1.1 4.8 1.8 2.6 3.6 12.2 2.0 7.0 0.0 27.6 13.7 10.1 0.0 4.5 1.5 1.0 0.0 1.2 1.3 9.6 6.6 2.8 3.1 0.3 1.6 1.0 0.3 1.2 1.7 5.1 0.2 1.0 KIF5A "D12S1889, MY050, NKHC, SPG10" ENSG00000155980 "Kinesin family member 5A" Q12840 12 57546026-57586633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Amyotrophic lateral sclerosis, Disease variant, Epilepsy, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "brain: 1628.2;choroid plexus: 951.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.7;Early spermatids: 12.2;Endometrial stromal cells: 12.9;Excitatory neurons: 28.4;Horizontal cells: 26.9;Inhibitory neurons: 21.7;Late spermatids: 15.2;Rod photoreceptor cells: 11.3" "Cancer enriched" "Detected in some" 5 "glioma: 26.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 33.2;K-562: 15.3;NTERA-2: 17.7;SCLC-21H: 34.4;U-87 MG: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004469, HPA073448" Enhanced Approved "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "Mitotic spindle" "HPA004469: AB_1079212, HPA073448: AB_2686601" "unprognostic (7.94e-2)" "unprognostic (4.95e-3)" "unprognostic (3.87e-1)" "unprognostic (3.34e-3)" "unprognostic (7.12e-2)" "unprognostic (4.22e-2)" "unprognostic (3.22e-5)" "unprognostic (2.82e-1)" "unprognostic (2.01e-1)" "unprognostic (1.52e-2)" "prognostic favorable (5.23e-4)" "unprognostic (7.61e-2)" "unprognostic (2.26e-4)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (4.12e-1)" "unprognostic (1.51e-1)" 0.4 10.6 1198.6 4.6 1243.7 4.2 0.5 1056.4 1628.2 2.5 951.3 4.5 3.6 3.8 1.4 1.4 0.6 0.7 0.6 1242.7 1056.4 0.8 0.2 0.8 0.7 1103.5 1046.7 0.6 2.6 9.0 21.3 0.1 1113.3 0.9 1.9 48.0 1.1 0.6 0.3 1.1 2.5 2.0 1002.7 0.8 1.3 4.8 1052.3 0.1 2.3 0.1 0.4 0.5 1.5 1313.2 0.5 0.1 7.2 5.7 0.0 0.0 0.6 1.4 1.3 2.2 3.5 1.2 0.2 3.2 0.4 1.9 1.3 0.8 3.8 0.1 2.5 33.2 4.1 0.5 1.8 7.0 1.9 1.5 1.3 1.0 0.4 1.6 0.1 0.5 0.5 2.8 15.3 9.4 0.0 0.6 0.8 0.0 17.7 0.0 0.0 0.5 0.2 0.3 1.1 0.5 34.4 9.1 0.0 1.6 0.0 2.0 0.9 0.2 0.9 0.6 5.3 1.1 2.1 5.3 7.7 1.9 14.5 0.1 0.6 0.2 0.4 0.1 1.0 0.5 1.6 0.7 0.7 1.2 0.3 0.5 0.9 2.2 1.1 0.3 1.1 0.3 1.0 0.4 1198.6 1243.7 1056.4 1628.2 1242.7 1056.4 1103.5 1046.7 1113.3 1002.7 1052.3 1313.2 0.1 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 40.7 0.1 0.9 2.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 12.2 0.5 12.9 0.7 0.0 0.4 28.4 0.2 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 26.9 21.7 0.2 0.0 0.0 0.2 15.2 0.0 0.1 0.0 0.0 0.0 6.4 0.0 8.5 3.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.7 3.3 7.9 0.0 0.1 0.0 0.3 0.0 0.1 0.1 KLC1 "hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A" ENSG00000126214 "Kinesin light chain 1" Q07866 14 103561896-103714249 "Predicted intracellular proteins" "Host-virus interaction" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 397.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009798, HPA044617, HPA052450" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 14000 "Cluster 26: Non-specific - Mitochondria" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009798: AB_2280879, HPA044617: AB_2679024, HPA052450: AB_2681838" "unprognostic (6.93e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (7.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.21e-3)" "unprognostic (2.67e-2)" "unprognostic (9.21e-2)" "unprognostic (5.62e-2)" "prognostic favorable (6.75e-4)" "unprognostic (6.84e-3)" "prognostic unfavorable (7.17e-4)" "unprognostic (6.58e-2)" "unprognostic (8.69e-2)" "unprognostic (4.05e-1)" "unprognostic (1.49e-1)" 70.8 49.4 282.9 42.2 302.0 50.3 63.0 273.5 358.7 74.8 220.4 89.9 26.2 71.5 43.9 66.0 65.0 38.4 100.0 310.6 299.8 35.6 29.9 66.0 44.2 378.9 305.0 62.8 43.0 48.5 86.7 45.9 397.0 47.1 34.3 158.6 54.2 47.1 123.4 68.2 48.7 58.0 300.0 49.0 53.9 45.6 301.7 40.2 48.6 71.5 47.4 66.5 69.8 304.0 57.0 74.2 138.6 76.3 92.6 102.8 65.5 129.5 105.4 118.6 81.7 64.0 60.8 75.8 65.2 139.3 53.2 93.0 85.8 69.6 112.0 89.9 43.9 41.6 92.8 66.1 106.8 83.4 79.5 73.4 109.3 89.6 112.1 126.5 104.2 52.8 63.5 83.7 104.4 94.6 56.9 74.0 45.6 90.1 140.4 53.0 60.6 38.2 74.7 122.5 165.1 93.5 105.7 52.7 90.2 85.9 47.9 40.1 152.7 88.4 43.5 123.1 74.1 65.9 50.0 83.3 101.7 47.7 97.0 5.5 4.6 9.8 7.3 4.6 6.6 5.0 6.5 7.8 5.1 6.8 5.7 5.0 5.0 3.1 6.5 7.6 7.0 2.9 282.9 302.0 273.5 358.7 310.6 299.8 378.9 305.0 397.0 300.0 301.7 304.0 45.2 44.8 32.6 92.4 24.3 26.0 45.1 30.1 13.6 140.8 18.7 19.7 39.3 15.7 21.5 20.2 52.1 22.6 29.5 17.9 9.8 42.9 8.0 30.8 41.8 45.5 44.9 13.2 84.1 30.7 30.6 37.4 27.0 43.2 33.6 31.5 39.3 18.9 30.5 138.0 80.8 24.3 28.5 19.9 23.8 17.0 38.5 24.4 39.2 73.1 36.3 45.4 20.6 57.3 89.8 71.2 17.3 48.2 26.2 46.6 15.8 5.1 23.8 106.1 26.3 46.4 46.8 64.8 83.3 20.1 17.6 42.1 30.8 17.1 17.5 38.4 KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: AB_10795524, HPA040434: AB_10795367" "unprognostic (1.29e-1)" "unprognostic (4.95e-3)" "unprognostic (2.99e-1)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (6.27e-3)" "unprognostic (1.60e-1)" "unprognostic (3.49e-2)" "unprognostic (1.64e-3)" "unprognostic (4.57e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (8.08e-2)" 15.2 18.0 18.8 9.5 25.4 3.6 15.9 33.0 78.1 27.3 0.0 28.5 9.8 27.1 6.3 18.2 21.6 8.9 32.1 26.6 12.7 22.4 8.2 18.9 9.1 39.8 10.8 24.6 15.5 15.2 48.3 7.2 37.0 28.7 4.7 28.4 15.9 16.0 57.8 18.3 16.3 11.2 5.7 13.7 20.2 32.2 23.1 25.1 17.7 14.2 6.4 27.2 21.7 35.8 49.4 58.2 28.3 16.9 16.9 13.5 21.9 34.1 24.2 34.2 26.1 31.9 14.3 21.3 31.9 25.6 43.9 40.7 29.3 33.2 11.4 35.7 37.2 4.4 48.0 22.4 32.1 9.9 22.7 13.5 42.7 40.1 32.8 22.0 16.1 26.2 24.1 29.0 27.8 69.2 56.8 15.0 27.8 14.2 49.2 21.4 14.6 30.1 27.2 27.4 76.3 37.5 24.6 22.1 41.3 15.7 36.3 6.7 26.8 55.5 49.8 68.2 45.5 30.7 27.4 11.9 39.3 6.7 22.9 0.0 0.2 0.5 2.4 0.1 3.1 1.9 1.1 1.6 0.3 3.2 1.1 1.4 0.3 1.3 0.2 2.1 0.3 1.1 18.8 25.4 33.0 78.1 26.6 12.7 39.8 10.8 37.0 5.7 23.1 35.8 4.0 3.2 1.5 8.8 8.9 8.9 9.2 11.1 7.4 34.4 10.1 7.2 2.4 7.2 5.5 12.9 12.5 9.9 5.1 3.1 13.7 14.8 10.1 7.7 6.2 5.2 37.1 0.8 20.7 8.2 18.2 6.5 13.7 9.7 0.0 8.6 3.9 2.3 3.1 55.5 19.0 7.2 18.3 3.2 4.0 4.6 8.7 2.8 12.4 5.6 6.3 14.6 4.1 4.0 6.2 19.1 4.9 13.9 9.1 18.2 3.9 10.3 7.3 35.2 0.0 9.5 13.3 26.2 29.8 8.9 9.7 12.7 8.2 3.4 4.9 8.5 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "Kruppel like factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 436.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 2075.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013529, HPA069585" Supported Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB013529: AB_2533431, HPA069585: AB_2686157" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.47e-3)" "unprognostic (4.53e-2)" "unprognostic (1.47e-1)" "unprognostic (7.55e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.83e-2)" "unprognostic (1.36e-2)" "unprognostic (2.35e-2)" "prognostic favorable (2.28e-4)" "unprognostic (8.07e-3)" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (1.37e-2)" 211.3 46.9 19.0 122.1 18.0 436.6 129.7 19.2 22.4 95.4 21.9 92.1 55.4 98.1 17.7 165.5 77.2 181.9 49.7 18.0 19.2 64.1 141.8 117.0 65.4 29.4 20.1 47.3 118.3 31.8 12.0 98.2 25.2 32.8 99.6 18.4 73.8 33.7 84.9 197.1 106.0 208.2 22.7 64.3 73.2 14.6 23.0 56.8 193.9 41.3 45.0 136.3 92.7 25.0 55.0 14.7 27.2 9.0 155.1 154.3 17.1 91.7 46.5 95.9 64.8 38.0 71.4 15.6 20.8 100.0 74.5 32.7 17.0 84.9 79.5 76.6 10.2 2.2 17.5 35.8 66.4 10.3 51.5 51.4 158.2 68.6 129.3 34.2 99.3 10.1 17.5 117.9 123.6 4.0 19.4 15.9 10.2 29.2 26.0 12.6 28.2 55.5 94.1 53.4 12.0 11.5 22.5 64.0 142.8 73.5 32.0 8.6 130.9 128.7 17.8 76.9 43.0 22.6 78.1 28.6 34.7 13.7 40.8 318.8 85.2 234.1 129.8 74.2 115.9 81.1 147.4 131.5 67.6 70.9 44.9 69.0 391.6 72.5 104.6 152.8 120.6 148.7 19.0 18.0 19.2 22.4 18.0 19.2 29.4 20.1 25.2 22.7 23.0 25.0 511.0 1246.8 489.4 14.0 716.9 585.5 1298.4 625.8 1227.0 39.6 985.9 630.0 63.6 544.7 451.9 138.0 33.3 163.1 518.3 1507.0 21.5 808.6 58.0 1065.6 618.9 469.9 397.3 77.9 18.5 553.0 473.8 545.5 1120.3 1905.9 626.7 195.9 248.4 309.9 583.6 37.0 10.0 746.7 429.3 968.7 885.1 53.2 130.5 992.1 483.8 58.1 609.8 42.9 150.4 7.5 4.3 857.9 949.9 133.9 1172.5 600.2 1009.9 97.4 342.0 90.1 138.1 194.8 441.8 9.0 19.4 2075.6 628.2 195.9 920.5 67.1 542.0 572.5 KLF9 BTEB1 ENSG00000119138 "Kruppel like factor 9" Q13886 9 70384597-70414624 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 264.3;Skeletal myocytes: 223.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.4;ASC TERT1: 83.0;HHSteC: 107.4;HSkMC: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029308 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA029308: AB_10601923" "unprognostic (2.12e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.69e-2)" "unprognostic (5.86e-2)" "unprognostic (1.37e-1)" "unprognostic (3.64e-3)" "unprognostic (4.34e-1)" "unprognostic (5.55e-1)" "unprognostic (9.47e-2)" "unprognostic (7.86e-2)" "unprognostic (3.44e-1)" "prognostic favorable (6.59e-6)" "unprognostic (1.43e-3)" "unprognostic (1.75e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" 82.0 36.5 12.5 22.8 22.1 18.2 67.6 29.8 22.5 29.9 14.9 66.5 15.3 56.5 16.7 41.1 73.0 42.6 54.7 15.7 14.4 54.9 91.3 71.6 14.4 21.3 21.1 63.4 52.9 51.1 25.5 10.2 17.3 36.5 26.2 19.2 35.4 24.4 123.3 40.8 33.2 58.9 15.6 22.9 48.9 7.7 21.7 12.1 57.1 94.7 14.3 43.4 37.2 19.1 0.4 0.6 0.0 7.8 60.4 83.0 0.8 4.1 27.1 1.4 3.0 0.1 3.6 0.1 3.0 7.5 2.0 0.1 11.9 18.4 2.8 0.0 9.3 4.2 13.1 2.4 107.4 2.1 10.9 71.6 18.4 1.1 25.9 37.1 23.9 1.8 8.4 16.4 10.2 1.3 0.3 6.2 0.7 1.2 3.9 0.0 3.7 10.9 5.0 0.0 1.0 5.2 37.3 21.5 45.2 2.5 7.1 6.7 32.8 7.1 5.1 8.2 2.2 11.8 13.5 0.6 6.4 6.6 35.9 0.7 0.1 0.1 0.4 0.1 0.6 0.9 0.5 0.4 0.3 0.6 0.7 0.4 0.0 0.1 0.2 0.4 0.6 0.1 12.5 22.1 29.8 22.5 15.7 14.4 21.3 21.1 17.3 15.6 21.7 19.1 264.3 41.7 25.5 25.8 36.5 48.2 62.7 13.0 97.3 45.3 48.3 34.7 74.1 64.3 22.3 14.7 20.9 0.2 51.0 36.7 31.3 10.5 22.3 40.6 171.6 124.3 13.8 14.5 32.1 13.1 0.5 180.8 55.5 59.6 7.6 2.0 109.9 158.8 3.7 80.8 13.7 32.3 14.2 70.1 44.6 18.1 90.7 81.3 39.2 29.0 9.7 126.1 19.6 3.0 11.1 12.8 26.1 85.0 30.2 74.0 54.5 39.7 17.4 10.1 78.9 223.8 203.5 2.1 3.2 72.7 34.2 0.0 54.9 16.3 31.9 33.3 KLHDC2 "HCLP-1, LCP" ENSG00000165516 "Kelch domain containing 2" Q9Y2U9 14 49768130-49786385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000628 Approved Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nuclear bodies" "HPA000628: AB_2666051" "unprognostic (2.65e-1)" "unprognostic (8.29e-2)" "unprognostic (1.30e-2)" "unprognostic (9.01e-2)" "unprognostic (2.57e-2)" "unprognostic (5.52e-3)" "unprognostic (4.54e-2)" "unprognostic (9.72e-3)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (4.81e-3)" "unprognostic (6.77e-3)" "prognostic favorable (2.75e-10)" "unprognostic (2.20e-2)" "unprognostic (2.08e-1)" "unprognostic (1.32e-2)" "unprognostic (9.34e-2)" 21.5 22.3 12.8 8.6 13.3 10.1 19.6 13.7 16.1 18.8 15.0 23.8 18.4 20.7 14.8 15.0 17.0 13.8 38.0 14.4 14.0 34.1 49.1 14.5 10.9 12.4 12.3 25.1 30.3 16.8 17.7 12.7 13.9 18.5 18.0 23.9 20.1 20.1 53.0 18.8 21.6 14.1 13.3 12.3 24.4 23.3 12.6 15.2 28.2 38.2 10.5 22.3 16.2 14.9 14.7 12.2 22.5 11.0 31.7 27.5 23.7 15.0 28.8 18.8 19.0 7.1 19.6 29.1 20.4 27.4 10.8 12.8 13.9 13.9 15.9 20.1 14.7 9.1 8.6 17.0 23.1 19.6 7.8 28.6 23.5 8.6 16.9 23.1 17.4 24.6 11.8 21.5 15.1 17.3 20.1 8.6 16.6 17.0 34.8 15.3 24.0 18.1 8.6 31.2 27.4 22.0 25.1 46.4 17.1 17.2 17.8 7.4 14.9 17.2 13.3 13.7 7.8 29.0 19.7 17.1 9.7 10.0 9.2 12.3 9.1 19.9 11.1 6.1 13.8 18.2 16.8 17.4 9.0 19.0 23.5 15.8 8.4 16.8 5.8 6.8 18.0 12.3 12.8 13.3 13.7 16.1 14.4 14.0 12.4 12.3 13.9 13.3 12.6 14.9 40.6 41.7 52.4 30.3 42.1 48.9 53.5 64.8 53.5 65.1 48.6 40.9 9.3 77.2 53.9 47.8 50.1 102.5 40.7 68.9 107.6 59.8 96.8 44.8 41.9 36.4 57.2 47.8 30.6 85.8 68.6 51.2 67.2 38.7 30.4 62.8 45.3 91.8 33.2 65.6 35.4 75.3 63.1 28.7 33.6 27.1 81.4 26.5 39.2 18.7 36.3 73.9 54.6 28.1 33.1 54.8 78.9 77.5 74.5 53.9 143.9 170.1 27.8 98.1 65.7 46.3 90.5 238.7 93.2 42.7 66.3 82.4 44.9 54.7 78.9 55.5 KLHDC9 KARCA1 ENSG00000162755 "Kelch domain containing 9" Q8NEP7 1 161098361-161100346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 29.0" "Group enriched" "Detected in many" 4 "Early spermatids: 424.7;Late spermatids: 448.2;Spermatocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.5;HEK 293: 1.8;MCF7: 1.4;T-47d: 1.4;U-266/70: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043197 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA043197: AB_2678359" "unprognostic (1.79e-1)" "unprognostic (2.26e-1)" "unprognostic (4.71e-2)" "unprognostic (1.04e-3)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (1.62e-1)" "unprognostic (4.87e-3)" "unprognostic (6.31e-2)" "prognostic favorable (4.20e-6)" "unprognostic (1.81e-3)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.53e-1)" "unprognostic (5.51e-2)" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" 0.4 3.0 1.3 0.1 1.8 0.0 0.7 1.0 2.9 1.1 2.1 1.4 0.2 1.4 0.5 0.5 2.2 0.0 0.9 1.7 2.2 4.7 1.9 0.8 0.0 1.7 1.8 1.0 2.4 1.1 4.6 0.0 1.6 1.7 0.2 0.4 1.0 0.4 0.7 0.3 0.8 0.0 1.2 0.3 1.3 29.0 2.4 0.0 2.4 0.1 0.1 1.0 0.5 0.9 0.1 1.1 0.4 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 1.5 1.8 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.5 0.2 0.9 1.0 0.0 0.7 0.2 0.0 1.0 0.4 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.8 1.0 2.9 1.7 2.2 1.7 1.8 1.6 1.2 2.4 0.9 2.4 0.0 6.7 8.8 1.5 0.9 11.7 11.5 0.6 13.7 15.3 16.3 9.3 14.3 11.7 29.5 2.1 2.3 0.4 7.6 56.7 10.2 424.7 57.5 2.8 3.4 5.4 0.0 8.9 5.5 3.6 3.2 3.1 10.3 1.3 1.6 3.9 9.5 0.6 3.3 6.8 10.6 16.2 0.6 0.7 448.2 8.1 0.9 7.2 2.8 0.6 35.1 1.0 6.0 1.7 3.9 8.2 8.2 2.1 6.4 2.5 47.8 77.8 20.0 13.1 2.8 4.4 198.1 15.6 2.6 0.9 0.8 1.2 1.7 8.7 8.2 KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.1;Excitatory neurons: 42.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: AB_2732488" "unprognostic (4.15e-1)" "unprognostic (9.34e-3)" "unprognostic (5.37e-2)" "prognostic favorable (4.88e-6)" "unprognostic (1.17e-1)" "unprognostic (2.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.19e-3)" "unprognostic (2.20e-1)" "unprognostic (8.99e-2)" "prognostic favorable (3.85e-6)" "unprognostic (3.94e-2)" "prognostic favorable (1.34e-8)" "unprognostic (3.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.64e-2)" "unprognostic (1.08e-2)" 13.7 14.2 24.1 10.2 23.0 11.3 11.9 25.9 25.1 20.5 18.2 16.6 7.7 20.4 17.2 8.0 17.9 13.6 14.2 22.9 21.4 15.6 10.8 11.8 17.6 18.0 18.1 22.3 16.5 22.9 19.6 11.6 18.7 18.7 10.6 15.3 14.0 18.0 22.1 11.7 10.4 21.7 14.8 15.6 12.2 10.2 23.1 8.0 20.8 18.0 20.7 13.4 10.9 21.2 17.1 16.5 37.5 29.9 30.6 35.5 9.0 21.4 37.6 21.0 23.6 8.2 6.4 11.9 7.0 37.3 16.9 21.3 25.6 9.2 18.1 25.9 15.1 12.6 17.4 8.3 30.6 2.6 11.7 26.9 14.2 19.3 12.4 26.8 31.3 9.1 32.7 11.4 20.7 25.9 2.5 15.6 6.3 14.1 11.4 23.5 13.8 0.5 12.3 19.9 19.9 20.3 23.0 16.9 15.8 12.3 15.7 9.3 14.2 25.1 12.2 17.5 8.9 6.4 7.4 7.9 13.5 11.1 16.6 8.9 4.6 19.3 8.1 6.3 6.4 8.3 10.2 7.5 15.5 6.2 7.7 8.3 10.6 16.6 8.3 5.6 19.2 6.5 24.1 23.0 25.9 25.1 22.9 21.4 18.0 18.1 18.7 14.8 23.1 21.2 4.6 0.0 3.7 41.1 8.2 1.7 2.8 8.4 4.0 11.7 4.3 5.2 4.8 10.0 5.3 9.2 4.2 17.9 5.2 2.9 3.9 8.4 0.8 3.2 7.1 4.8 3.0 1.3 42.9 2.6 6.6 9.2 5.1 3.9 5.1 14.2 4.2 6.3 7.9 13.5 51.1 5.2 12.2 5.7 4.9 1.8 12.2 4.8 1.8 16.9 4.2 13.9 7.2 41.2 26.8 5.6 3.5 19.9 5.4 3.9 3.0 10.9 4.3 6.7 6.6 4.7 5.3 17.3 15.4 2.8 1.4 13.4 7.8 17.7 3.8 1.8 KLHL35 FLJ33790 ENSG00000149243 "Kelch like family member 35" Q6PF15 11 75422394-75433203 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.2;testis: 9.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 39.6;Early spermatids: 25.9;Late spermatids: 28.4;Spermatogonia: 56.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 15.8;HMC-1: 10.3;PC-3: 8.9;SiHa: 18.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039864, HPA070736" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Centrosome" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Nucleoli fibrillar center" "HPA039864: AB_10794204, HPA070736: " "unprognostic (3.53e-2)" "prognostic favorable (4.63e-4)" "unprognostic (5.40e-2)" "unprognostic (1.97e-1)" "unprognostic (6.88e-2)" "unprognostic (4.15e-3)" "unprognostic (4.98e-2)" "unprognostic (3.92e-2)" "unprognostic (6.52e-2)" "unprognostic (2.87e-1)" "unprognostic (2.67e-1)" "unprognostic (4.39e-2)" "unprognostic (8.68e-3)" "unprognostic (1.59e-1)" "unprognostic (1.05e-1)" "unprognostic (3.11e-2)" "unprognostic (1.28e-1)" 0.6 0.8 3.9 0.0 4.9 0.0 0.9 1.9 3.9 0.7 1.3 0.2 0.0 0.3 0.0 0.4 0.4 0.1 0.8 3.5 5.1 0.3 0.0 0.7 0.0 4.4 3.4 0.2 1.8 0.0 0.9 0.0 5.2 0.2 0.0 0.6 0.8 0.1 0.4 0.9 0.1 0.1 2.7 1.1 1.1 9.3 4.4 0.1 0.6 0.2 0.0 0.3 0.3 3.8 0.0 0.3 0.1 0.0 0.2 1.3 0.0 0.9 0.0 0.9 0.1 15.8 1.3 0.0 4.3 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.8 4.1 10.3 0.2 0.2 0.0 0.0 0.1 0.4 2.7 0.0 0.0 1.1 0.7 0.3 0.1 0.2 3.2 8.9 0.0 0.0 0.9 0.7 0.2 1.2 1.0 18.4 3.4 0.0 0.0 3.4 2.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.2 0.0 0.4 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.9 4.9 1.9 3.9 3.5 5.1 4.4 3.4 5.2 2.7 4.4 3.8 0.7 9.6 3.4 0.3 1.1 1.3 1.8 0.5 4.0 39.6 6.4 4.8 1.0 1.5 2.8 3.7 8.4 1.5 0.7 0.6 3.9 1.7 25.9 2.1 3.0 1.1 4.2 0.4 3.9 3.1 1.7 3.0 2.6 4.0 4.5 1.5 2.9 0.1 1.2 1.7 3.5 1.4 0.0 1.2 2.1 28.4 2.8 2.9 1.8 0.0 1.6 2.5 3.1 0.0 4.4 3.7 0.4 1.2 0.1 1.3 0.3 0.4 1.6 11.1 6.6 1.3 1.6 10.2 56.7 0.9 2.3 2.5 1.1 2.2 0.7 1.4 KLHL41 "KBTBD10, Krp1, SARCOSIN" ENSG00000239474 "Kelch like family member 41" O60662 2 169509702-169526258 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 42 "skeletal muscle: 5038.6;tongue: 3473.7" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 108.1;Skeletal myocytes: 251.8" "Group enriched" "Detected in some" 9 "head and neck cancer: 10.8;prostate cancer: 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HSkMC: 21.6;LHCN-M2: 35.4;RH-30: 55.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021165, HPA021753, HPA021760" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Nucleoplasm, Plasma membrane" "HPA021165: AB_1852087, HPA021753: AB_1852089, HPA021760: AB_1852091" "unprognostic (2.44e-2)" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (2.94e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" "unprognostic (2.05e-1)" "unprognostic (5.46e-3)" "unprognostic (1.88e-1)" "unprognostic (5.38e-2)" "unprognostic (6.65e-4)" "unprognostic (9.64e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-2)" "unprognostic (1.52e-1)" 1.5 0.5 1.7 0.2 1.4 0.0 2.0 3.1 1.8 1.0 1.4 1.4 0.1 0.8 1.5 75.1 1.2 6.7 100.3 1.2 1.6 0.8 0.9 2.7 0.3 0.9 2.5 1.1 1.1 0.5 5.8 0.1 1.5 50.0 0.3 16.1 52.1 0.7 5038.6 4.6 0.8 0.6 0.9 0.8 1.3 2.6 5.1 1.7 2.2 3473.7 0.3 5.9 0.9 1.4 0.0 0.1 0.0 0.6 0.4 2.7 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.2 0.2 0.0 21.6 0.5 0.3 0.0 0.2 0.1 0.2 0.1 0.0 35.4 0.1 0.1 0.2 0.0 0.0 0.2 0.0 55.9 0.0 0.2 0.1 0.7 0.1 0.1 0.0 1.5 0.1 0.0 0.1 0.0 0.4 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 3.1 1.8 1.2 1.6 0.9 2.5 1.5 0.9 5.1 1.4 0.0 0.0 0.5 1.3 0.0 0.1 0.5 0.1 0.0 2.4 0.2 0.1 108.1 0.0 2.0 0.0 8.4 0.0 0.0 0.1 0.0 0.5 5.8 1.3 0.2 1.0 1.2 0.0 4.1 0.5 0.0 6.4 0.0 0.1 0.0 0.2 0.4 0.2 0.2 0.0 4.6 0.1 0.0 0.3 0.0 2.9 0.9 0.8 0.0 3.7 0.0 0.7 0.0 1.5 2.3 0.7 0.1 1.2 0.0 0.3 0.0 0.3 4.1 5.8 0.0 251.8 1.8 4.1 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.1 KLHL6 FLJ00029 ENSG00000172578 "Kelch like family member 6" Q8WZ60 3 183487551-183555706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 31.0" "Cell type enhanced" "Detected in many" "B-cells: 35.7;Endometrial ciliated cells: 28.3;granulocytes: 51.1;Hofbauer cells: 24.1;Macrophages: 33.3;Plasma cells: 63.6;Respiratory ciliated cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.3;HEL: 26.6;HMC-1: 26.7;U-266/70: 82.1;U-266/84: 45.5;U-698: 121.3" "Low region specificity" "Detected in all" HPA024512 Uncertain Approved "Plasma membrane,Microtubules,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Centriolar satellite" "Plasma membrane, Microtubules, Mitotic spindle" "HPA024512: AB_2131015" "unprognostic (8.46e-2)" "unprognostic (3.67e-4)" "unprognostic (1.48e-2)" "unprognostic (6.03e-4)" "unprognostic (5.15e-2)" "unprognostic (1.30e-3)" "unprognostic (1.39e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (9.62e-2)" "unprognostic (8.24e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (3.53e-4)" "unprognostic (1.81e-1)" "unprognostic (3.68e-2)" "unprognostic (2.42e-1)" "unprognostic (5.73e-2)" 1.5 0.7 0.7 11.8 0.8 3.5 0.9 1.0 1.0 0.8 0.7 2.5 2.5 0.6 0.2 0.6 4.8 2.1 0.7 0.6 1.4 0.4 1.0 4.2 29.3 2.6 1.4 0.3 0.6 0.2 0.2 1.9 2.0 0.5 2.3 0.1 1.3 0.1 0.2 0.1 4.8 0.7 1.5 6.3 4.1 0.2 3.1 10.0 0.6 0.3 31.0 1.8 0.3 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 26.6 0.0 0.0 0.0 7.3 26.7 0.0 0.0 0.0 0.0 0.0 4.6 0.5 0.4 18.4 0.0 0.0 8.8 4.1 0.0 0.0 0.0 14.8 0.1 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 0.0 0.1 0.0 0.1 82.1 45.5 121.3 0.0 8.0 0.0 7.8 2.8 11.8 0.6 2.2 0.7 3.6 2.4 1.0 2.0 2.4 2.9 1.8 2.4 2.2 2.7 4.6 4.2 2.6 0.7 0.8 1.0 1.0 0.6 1.4 2.6 1.4 2.0 1.5 3.1 3.7 4.0 6.4 6.5 0.7 35.7 1.1 1.7 0.6 0.6 0.6 0.3 0.4 4.8 0.0 5.4 0.0 2.1 0.2 16.6 0.2 0.0 0.1 2.0 28.3 0.5 4.6 0.0 7.6 0.3 0.0 0.3 1.7 2.0 0.8 51.1 8.1 1.1 0.2 24.1 0.0 0.3 0.0 0.0 20.7 22.4 0.8 0.3 33.3 8.8 14.0 10.1 0.3 5.2 1.0 0.3 0.0 0.1 0.0 63.6 1.2 0.0 0.4 24.4 0.7 0.0 1.8 1.5 0.3 0.4 0.1 0.6 0.5 16.8 0.0 0.2 1.2 KLHL7 "KLHL6, RP42, SBBI26" ENSG00000122550 "Kelch like family member 7" Q8IXQ5 7 23105758-23177914 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.8" "Cell type enhanced" "Detected in all" "Early spermatids: 560.6;Late spermatids: 242.7;Oligodendrocyte precursor cells: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029491, HPA029492" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029491: AB_10599605, HPA029492: AB_10600881" "unprognostic (1.24e-2)" "unprognostic (4.45e-1)" "unprognostic (1.77e-1)" "unprognostic (4.55e-2)" "unprognostic (1.29e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (3.78e-1)" "unprognostic (6.10e-2)" "unprognostic (6.41e-3)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "prognostic favorable (8.98e-5)" "unprognostic (2.46e-2)" "unprognostic (3.55e-3)" "unprognostic (3.23e-2)" "unprognostic (2.27e-2)" 9.5 18.8 12.8 7.0 13.3 12.4 13.0 16.3 15.9 10.5 12.1 9.2 7.8 11.5 12.2 9.0 9.7 9.7 50.8 12.5 13.1 11.9 10.4 7.7 8.3 12.6 12.7 11.8 7.7 10.8 7.3 8.6 12.3 10.1 7.9 14.9 8.5 8.1 9.1 10.9 6.9 10.5 12.2 8.0 6.3 42.2 13.4 12.4 9.2 9.7 9.1 8.7 9.4 14.7 24.7 20.7 55.7 66.3 26.8 23.2 20.3 21.3 31.5 30.7 35.6 25.3 17.5 24.1 16.8 26.2 50.5 26.2 21.5 15.0 25.8 6.4 15.5 15.9 16.7 32.9 20.0 32.5 12.0 20.7 19.1 35.2 28.8 24.2 39.6 29.4 28.3 25.5 50.7 28.4 27.3 51.3 77.0 16.7 24.5 23.7 31.2 22.2 29.2 21.0 33.5 32.5 46.2 22.7 23.3 33.9 18.9 16.9 17.0 25.7 26.6 56.9 25.7 39.9 35.3 58.6 17.0 33.8 31.5 44.1 15.3 67.2 13.0 17.9 13.7 9.2 13.8 12.3 11.1 11.9 10.1 10.0 14.4 9.5 15.8 8.0 16.7 12.6 12.8 13.3 16.3 15.9 12.5 13.1 12.6 12.7 12.3 12.2 13.4 14.7 12.1 22.4 5.5 45.7 13.0 23.6 18.2 13.0 18.2 23.7 12.3 13.5 101.2 8.6 11.3 9.2 29.2 20.7 14.4 5.7 11.7 17.7 560.6 18.3 16.7 15.8 10.8 25.6 74.5 17.6 27.1 19.8 10.2 13.2 21.5 16.3 13.2 7.0 19.7 37.0 75.2 7.6 14.2 16.0 17.2 242.7 16.8 12.6 12.4 35.6 13.4 30.3 8.2 168.9 45.6 19.4 1.9 20.7 12.3 11.5 7.4 13.5 18.8 16.3 6.6 14.3 17.9 83.7 19.7 24.6 33.8 23.7 17.2 12.1 7.0 24.0 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 253.0;esophagus: 94.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 23.9;Breast myoepithelial cells: 16.1;Collecting duct cells: 11.0;Oligodendrocytes: 87.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 575.5;CAPAN-2: 1346.5" "Region enhanced" "Detected in all" "pons and medulla: 167.8" "Region enhanced" "Detected in many" "spinal cord: 371.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Yes No 10000000 "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" 0.2 0.0 71.8 0.0 135.8 0.0 7.2 170.8 119.8 53.1 45.6 0.1 0.2 1.5 0.4 94.2 28.9 3.5 0.0 72.9 94.3 20.4 0.0 0.0 0.0 213.8 130.8 0.8 0.0 0.0 0.7 0.0 182.1 0.1 0.0 0.0 15.8 2.2 0.0 9.9 0.0 0.0 123.6 5.8 0.1 0.9 118.1 1.5 0.0 0.0 36.4 0.0 27.4 253.0 575.5 0.0 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 67.7 1346.5 0.0 8.1 0.0 0.6 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.1 131.0 2.2 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 5.6 18.2 1.0 1.9 0.0 1.1 46.3 0.0 1.3 0.0 0.4 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 135.8 170.8 119.8 72.9 94.3 213.8 130.8 182.1 123.6 118.1 253.0 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 0.0 23.9 16.1 0.3 0.0 1.7 11.0 0.0 0.1 0.4 0.0 0.0 0.1 2.3 0.6 7.5 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 87.9 7.8 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 1.6 0.0 0.3 0.1 0.0 0.0 2.4 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KNDC1 "bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2, v-KIND, Very-KIND" ENSG00000171798 "Kinase non-catalytic C-lobe domain containing 1" Q76NI1 10 133160219-133226412 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.0;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 93.4;Excitatory neurons: 41.9;Inhibitory neurons: 36.3;Respiratory ciliated cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;EFO-21: 1.2;MCF7: 1.1;NTERA-2: 1.4;RPMI-8226: 2.1;SuSa: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039624, HPA056143" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" Vesicles "HPA039624: AB_10671045, HPA056143: " "unprognostic (2.32e-1)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (1.59e-3)" "unprognostic (1.96e-2)" "unprognostic (2.76e-1)" "unprognostic (5.61e-2)" "unprognostic (2.75e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-3)" "unprognostic (2.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-1)" "unprognostic (9.41e-2)" 1.5 13.7 31.1 0.1 17.9 0.0 0.2 8.4 44.0 2.3 0.0 0.3 0.0 2.8 0.7 0.2 9.0 0.2 0.3 19.8 9.1 0.8 6.5 2.8 0.0 17.3 13.3 8.5 0.5 0.4 27.5 0.4 10.3 1.1 0.0 0.9 0.6 0.9 0.0 0.2 0.2 0.4 3.0 0.5 0.3 1.8 22.7 0.0 2.5 0.0 0.0 0.2 0.9 13.1 0.2 0.3 0.2 1.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.2 0.0 1.2 0.1 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 31.1 17.9 8.4 44.0 19.8 9.1 17.3 13.3 10.3 3.0 22.7 13.1 0.0 0.0 9.0 93.4 0.2 0.0 0.1 0.4 0.0 1.6 0.2 0.0 2.4 1.5 4.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 1.5 0.2 3.0 0.0 41.9 0.0 0.1 1.4 0.0 0.3 0.0 1.5 0.4 4.6 0.2 1.7 36.3 0.0 0.0 1.0 0.4 1.0 3.7 1.2 0.0 5.6 0.3 4.5 0.0 6.6 2.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 25.9 1.0 0.0 0.1 0.5 0.0 1.7 0.0 0.3 0.1 0.4 1.2 0.0 0.0 KNOP1 "101F10.1, C16orf88, FAM191A, TSG118" ENSG00000103550 "Lysine rich nucleolar protein 1" Q1ED39 16 19701937-19718235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 166.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041079, HPA066169" Uncertain Enhanced "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" Cytosol "HPA041079: AB_10962350, HPA066169: AB_2685628" "unprognostic (6.55e-3)" "unprognostic (3.96e-1)" "unprognostic (2.16e-2)" "unprognostic (2.42e-2)" "unprognostic (8.57e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (3.75e-6)" "unprognostic (2.50e-2)" "unprognostic (2.03e-2)" "unprognostic (1.18e-3)" "unprognostic (5.84e-2)" "unprognostic (2.14e-2)" "unprognostic (7.91e-2)" "unprognostic (3.75e-2)" "unprognostic (3.62e-1)" "unprognostic (1.34e-3)" "unprognostic (1.08e-1)" 7.5 6.8 14.3 6.9 16.9 4.0 11.5 14.6 22.5 9.1 9.7 8.3 7.1 7.0 8.8 10.4 7.4 6.3 7.3 15.5 15.1 9.9 7.9 5.7 9.0 15.9 15.8 11.4 8.6 13.5 6.4 8.8 17.3 7.3 9.1 8.8 12.5 6.8 14.4 13.0 7.3 4.8 13.2 6.4 8.1 8.9 15.6 5.9 6.2 5.4 6.7 7.2 8.8 22.9 30.2 45.4 49.7 37.9 12.1 11.3 25.5 18.3 9.9 17.1 17.2 32.2 25.5 35.7 72.6 11.1 15.0 27.4 38.9 25.1 16.6 24.2 27.2 21.1 25.3 42.7 21.9 33.5 15.9 7.2 35.1 22.4 18.4 15.0 18.3 25.0 66.1 15.6 16.2 39.3 29.7 27.6 96.8 29.7 17.9 63.0 26.7 41.4 18.0 28.4 44.4 37.4 22.7 29.0 31.2 28.1 33.8 22.4 21.3 26.7 27.4 16.5 24.5 23.0 51.3 44.7 14.4 25.2 26.6 0.4 3.0 1.5 4.0 7.1 5.9 5.8 5.6 3.9 3.6 7.1 10.1 5.7 0.8 4.4 6.7 4.6 3.8 3.5 14.3 16.9 14.6 22.5 15.5 15.1 15.9 15.8 17.3 13.2 15.6 22.9 40.3 6.4 17.8 108.7 19.8 12.2 29.9 47.9 17.6 39.2 37.9 31.9 8.9 38.6 29.5 38.6 87.6 57.1 13.6 43.0 46.9 98.2 2.8 33.8 79.8 47.2 15.0 21.7 9.7 66.3 45.4 26.0 26.5 42.1 6.3 66.9 26.0 53.4 36.5 35.3 12.7 41.7 61.1 24.9 12.6 8.5 60.6 17.9 12.4 16.9 27.2 25.8 33.0 15.1 166.6 77.8 19.0 53.8 14.8 46.4 32.3 34.5 21.3 64.1 46.0 18.7 38.9 67.8 125.3 31.5 16.1 24.6 16.8 53.6 64.4 23.3 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 KPNB1 "IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97" ENSG00000108424 "Karyopherin subunit beta 1" Q14974 17 47649476-47685505 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029878, CAB034449, HPA050302" Supported Enhanced "Nucleoplasm,Nuclear membrane,Cytosol" Yes No 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB034449: AB_2133993, HPA029878: AB_10670041, HPA050302: AB_2681079" "unprognostic (2.57e-1)" "unprognostic (1.15e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (2.55e-7)" "unprognostic (7.18e-3)" "unprognostic (9.52e-2)" "unprognostic (5.47e-3)" "unprognostic (4.37e-2)" "unprognostic (8.41e-3)" "prognostic unfavorable (8.43e-6)" "unprognostic (1.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (3.44e-2)" 57.6 44.9 31.6 74.4 33.6 35.9 53.4 34.7 32.2 49.9 30.5 55.3 35.9 47.5 29.5 66.0 49.6 47.2 53.6 31.2 37.1 48.8 50.6 42.6 81.7 38.2 39.8 64.3 38.1 56.3 28.1 55.4 37.1 44.4 63.6 49.0 39.2 45.7 91.0 38.7 38.8 66.6 37.2 54.0 43.3 100.9 33.9 117.3 57.4 88.3 108.7 79.6 40.5 47.3 273.2 485.0 324.6 259.1 152.8 265.8 271.6 345.4 307.0 441.6 339.3 853.2 161.5 385.8 210.4 343.8 301.8 186.3 607.2 316.3 691.1 212.1 344.7 421.2 408.7 241.6 148.4 485.5 238.9 209.6 140.5 511.7 509.2 202.3 305.8 203.0 461.3 237.5 349.4 288.8 464.9 97.2 270.6 199.4 300.2 250.1 563.3 216.4 156.2 444.2 267.5 240.5 233.3 121.7 176.6 388.4 253.9 157.6 248.7 463.9 264.7 252.8 412.9 258.8 373.0 542.6 216.1 224.2 325.8 3.1 2.9 6.1 4.1 3.6 5.8 4.0 4.7 5.1 1.8 4.0 4.5 4.3 12.2 3.5 4.4 3.0 3.4 2.4 31.6 33.6 34.7 32.2 31.2 37.1 38.2 39.8 37.1 37.2 33.9 47.3 76.8 128.2 71.9 42.7 138.3 125.7 101.1 67.8 165.0 96.5 110.8 89.5 132.7 88.6 75.2 44.1 68.8 132.7 93.9 69.5 41.1 117.1 55.8 71.2 123.1 110.5 123.8 148.7 51.4 119.5 147.5 102.9 72.4 106.3 76.1 147.2 128.8 97.5 124.1 80.8 48.2 82.2 44.7 115.0 91.6 41.7 96.9 102.7 60.5 30.9 152.8 83.4 80.3 39.2 58.2 147.0 69.8 121.5 163.4 149.7 49.2 48.0 60.6 90.2 98.6 107.0 104.6 291.6 186.0 163.9 143.5 158.2 108.1 138.8 128.4 128.1 KPTN 2E4 ENSG00000118162 "Kaptin, actin binding protein" Q9Y664 19 47475150-47484265 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 23.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 23.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041710, HPA041796" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA041710: AB_10961904, HPA041796: AB_10962832" "unprognostic (4.80e-3)" "unprognostic (2.22e-1)" "unprognostic (7.24e-2)" "unprognostic (1.53e-1)" "unprognostic (5.54e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (9.30e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-2)" "unprognostic (5.51e-2)" "unprognostic (2.59e-2)" "prognostic unfavorable (7.82e-4)" "unprognostic (1.40e-1)" "unprognostic (8.72e-2)" "unprognostic (2.04e-1)" "unprognostic (2.34e-1)" 5.2 6.6 5.1 3.0 5.5 5.6 4.7 5.9 8.4 7.2 3.6 6.2 3.4 5.3 1.4 7.7 4.4 2.4 5.8 5.6 5.1 6.3 8.6 4.5 3.4 5.6 5.1 3.2 5.5 4.0 10.0 2.8 5.0 8.0 2.2 1.6 10.1 2.0 6.9 4.8 4.5 2.6 4.6 6.1 4.7 5.4 5.1 8.2 4.8 6.7 2.1 5.1 5.8 5.4 9.7 16.8 12.9 8.6 12.9 10.0 9.3 5.4 9.9 28.4 17.5 12.6 11.3 12.3 4.1 9.5 10.1 11.1 11.0 19.1 7.9 11.4 17.2 5.2 12.2 11.4 11.5 10.1 13.8 11.5 12.3 9.5 8.7 7.2 11.0 15.2 10.1 10.9 8.3 7.8 17.7 44.8 11.6 10.5 10.3 12.6 6.3 4.8 8.8 15.0 27.8 21.1 9.1 10.3 6.8 6.4 8.5 14.5 6.6 6.9 7.6 3.7 12.2 2.8 4.8 5.3 6.1 6.4 10.4 0.0 3.9 1.7 1.4 3.4 0.4 1.5 1.0 1.2 4.6 1.6 1.3 1.1 3.2 1.2 5.3 23.9 1.7 2.2 5.1 5.5 5.9 8.4 5.6 5.1 5.6 5.1 5.0 4.6 5.1 5.4 2.6 3.2 2.7 4.6 4.8 2.8 8.5 13.8 2.8 5.8 5.8 3.9 3.7 4.3 8.9 5.5 6.2 14.5 12.1 3.4 9.8 9.6 0.8 3.1 3.3 3.0 3.0 0.8 4.7 4.2 13.3 5.0 5.1 3.4 2.5 4.9 3.3 6.2 8.5 10.1 3.5 2.5 8.2 5.6 2.8 2.5 1.2 5.8 1.8 1.9 2.5 6.9 5.2 3.0 4.3 5.0 1.8 0.7 6.5 4.4 4.3 8.3 2.9 4.0 0.0 3.5 3.5 4.9 18.9 4.5 3.1 15.3 1.7 8.2 4.0 5.8 KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 59.1;Skeletal myocytes: 82.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "RH-30: 34.7;U-2197: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058513 Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No 1100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA058513: AB_2683739" 7.3 13.5 10.3 9.5 22.3 4.1 7.6 7.4 10.8 9.1 5.6 13.1 6.6 6.7 8.7 37.2 10.9 4.0 22.7 12.7 7.6 9.0 2.4 11.9 2.9 8.2 9.8 22.2 4.6 48.2 6.5 6.1 8.0 9.1 11.3 4.0 28.3 9.8 28.7 36.3 11.1 6.2 5.6 9.1 9.4 12.5 12.9 22.4 9.5 42.6 16.4 9.2 13.7 8.3 5.2 3.6 11.8 6.2 3.9 11.9 9.9 1.4 12.0 3.8 5.7 16.5 2.4 0.1 4.5 5.6 9.6 24.7 24.6 9.9 4.1 6.2 15.5 1.4 1.7 15.6 4.1 0.1 1.3 11.4 19.7 4.3 2.4 1.6 0.6 10.1 5.4 0.3 4.8 4.4 0.1 1.7 0.5 34.0 2.5 0.8 34.7 0.3 4.1 9.7 23.6 13.1 14.2 5.0 18.3 3.9 18.5 0.9 0.4 15.7 4.8 59.3 1.7 1.2 0.4 0.2 10.0 2.2 18.5 1.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 4.6 0.3 0.2 0.6 0.1 0.1 10.3 22.3 7.4 10.8 12.7 7.6 8.2 9.8 8.0 5.6 12.9 8.3 2.0 16.0 18.4 59.1 0.3 15.3 14.0 14.1 7.4 4.4 5.7 6.1 23.9 14.3 18.3 7.3 0.0 15.5 0.3 3.9 1.9 5.4 3.2 6.2 19.7 3.9 0.0 17.2 10.3 4.2 1.8 24.4 8.6 8.0 19.0 5.9 5.3 2.6 2.6 0.0 2.7 19.4 4.1 24.1 6.8 10.8 17.7 2.5 0.0 15.9 2.7 22.2 2.1 10.6 6.3 3.0 9.5 10.5 0.1 10.9 2.2 4.7 18.4 3.4 13.1 82.2 7.9 8.1 6.0 26.3 19.5 5.3 2.3 33.5 10.2 10.5 KRR1 "HRB2, RIP-1" ENSG00000111615 "KRR1 small subunit processome component homolog" Q13601 12 75490863-75511636 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043433, HPA051690" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA043433: AB_10960988, HPA051690: AB_2681574" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (8.21e-2)" "unprognostic (1.71e-1)" "unprognostic (2.02e-1)" "unprognostic (4.71e-2)" "unprognostic (6.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-1)" "unprognostic (5.85e-2)" "unprognostic (1.88e-1)" "unprognostic (2.32e-2)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-2)" 15.2 14.2 6.5 15.6 7.0 43.9 16.7 9.3 10.4 11.6 7.6 12.5 12.1 15.0 9.0 16.0 9.8 10.0 11.8 6.9 8.2 16.2 20.4 11.5 19.0 6.6 7.3 15.0 10.7 20.3 8.0 14.5 7.0 13.2 10.9 16.0 19.3 9.8 23.5 12.7 10.3 10.9 7.4 12.6 12.7 12.0 7.5 17.9 14.9 22.7 18.0 15.9 9.8 8.2 59.4 48.1 29.2 27.1 21.8 20.1 54.1 51.0 31.7 38.5 24.8 35.7 30.7 62.2 40.3 23.9 39.0 30.5 39.1 43.0 42.4 52.0 39.9 60.9 25.0 41.8 26.4 107.0 37.1 21.3 35.8 44.8 41.7 39.1 26.6 57.4 67.7 19.8 38.2 39.2 63.1 30.8 43.6 32.4 42.4 49.9 56.1 37.4 42.6 73.6 35.4 29.6 48.0 33.7 59.5 27.9 56.2 42.9 34.4 36.2 24.1 37.7 53.2 38.8 52.3 39.0 19.6 37.0 66.2 13.3 3.2 13.2 13.1 6.5 16.4 23.0 18.3 15.0 5.5 20.6 18.6 17.9 1.5 12.9 5.5 15.3 18.2 7.6 6.5 7.0 9.3 10.4 6.9 8.2 6.6 7.3 7.0 7.4 7.5 8.2 62.9 70.5 49.2 13.4 64.0 49.1 104.3 70.3 48.9 56.4 41.1 50.5 25.6 24.3 55.7 40.5 33.3 68.5 86.4 18.7 58.7 50.9 5.4 52.5 63.8 46.7 18.0 55.8 25.3 49.0 55.7 48.2 21.4 62.6 38.0 41.3 31.1 40.9 29.5 74.0 24.3 25.7 46.8 24.2 21.3 7.6 52.5 30.0 12.4 6.5 42.4 66.4 66.9 19.1 16.3 42.8 28.1 53.4 37.9 45.6 19.2 47.0 42.3 55.5 13.1 79.2 50.2 72.6 61.1 46.8 44.3 70.5 65.4 59.6 29.3 63.2 KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4660.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 265.4" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in single" "HEL: 2.0" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" "HPA006299, CAB037321" Enhanced Approved "Golgi apparatus,Intermediate filaments,Cytosol" NA NA 9700000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments, Cytosol" "Golgi apparatus" "CAB037321: , HPA006299: AB_1079180" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" 3.0 0.5 0.0 0.1 0.0 1.0 81.9 0.0 0.0 0.8 0.0 0.9 1.6 0.4 0.3 1.1 0.1 0.0 1.7 0.0 0.0 0.5 1.2 1.0 0.5 0.0 0.0 0.5 1.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 1.6 0.0 47.8 4660.3 0.8 0.0 0.0 0.5 0.7 1.0 0.0 6.8 0.8 0.0 6.1 0.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.5 0.0 0.0 0.1 8.8 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 265.4 0.1 1.0 0.0 0.6 0.1 KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.6;skin 1: 16.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 31: Spermatids - Spermatogenesis" "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: AB_2680457" "unprognostic (6.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-2)" "unprognostic (9.46e-2)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.02e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 68.3" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Late spermatids: 1.1;Melanocytes: 3.6" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;cervical cancer: 2.6;head and neck cancer: 2.7;melanoma: 1.6;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HMC-1: 425.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA 1900000000 "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nuclear membrane, Cytosol" "HPA059347: AB_2683986" "unprognostic (5.19e-3)" "unprognostic (1.56e-3)" "unprognostic (5.24e-2)" "unprognostic (2.38e-2)" "unprognostic (6.85e-2)" "unprognostic (6.36e-2)" "unprognostic (3.17e-1)" "unprognostic (7.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (3.99e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 425.5 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 KRTAP25-1 KAP25.1 ENSG00000232263 "Keratin associated protein 25-1" Q3LHN0 21 30289145-30289514 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031438 Uncertain Approved "Nuclear membrane,Plasma membrane,Cytosol" NA NA "Nuclear membrane" "Plasma membrane, Cytosol" "HPA031438: AB_10610000" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KXD1 "BORCS4, C19orf50, FLJ25480, KXDL, MGC2749" ENSG00000105700 "KxDL motif containing 1" Q9BQD3 19 18557762-18569387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041507, HPA041599" Approved Approved "Nucleoli fibrillar center,Centrosome,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli fibrillar center, Centrosome, Cytosol" "HPA041507: AB_10795698, HPA041599: AB_10795502" "unprognostic (8.48e-2)" "unprognostic (5.30e-2)" "unprognostic (3.16e-3)" "unprognostic (1.35e-1)" "unprognostic (8.60e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (8.46e-4)" "unprognostic (7.36e-2)" "unprognostic (1.81e-2)" "unprognostic (5.25e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (7.71e-10)" "unprognostic (7.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.45e-2)" "unprognostic (1.63e-1)" 87.5 79.2 89.8 67.9 92.8 75.2 81.3 87.9 94.9 78.8 78.6 90.6 58.4 75.0 54.9 79.3 69.5 52.5 81.5 87.0 89.1 76.1 100.4 79.8 81.2 100.8 95.5 84.9 91.9 46.3 86.2 62.9 95.6 87.7 55.2 48.1 66.2 51.2 97.9 70.8 72.7 63.8 90.8 89.4 78.4 78.8 93.4 58.2 71.3 57.3 72.4 89.9 74.7 104.8 125.1 122.2 98.7 114.0 102.0 117.4 157.3 133.6 108.0 99.2 114.2 102.1 145.3 84.6 153.5 118.7 82.1 92.3 153.0 164.5 89.7 103.3 206.5 91.7 98.5 92.6 116.7 147.2 98.4 123.7 117.6 147.8 175.1 107.7 143.4 114.4 146.7 130.2 105.3 144.5 135.2 109.5 124.2 158.3 187.9 127.0 76.9 126.7 103.5 110.0 91.0 115.7 87.6 79.1 113.8 103.3 66.5 102.4 115.2 88.1 76.8 285.9 177.8 153.9 124.1 128.0 151.9 172.2 131.4 45.3 109.5 97.7 73.7 125.0 68.2 69.8 68.4 74.1 99.5 71.5 54.1 59.0 107.6 83.2 125.1 58.9 103.4 95.9 89.8 92.8 87.9 94.9 87.0 89.1 100.8 95.5 95.6 90.8 93.4 104.8 48.3 19.2 29.3 0.3 41.8 34.5 71.8 68.9 34.1 20.5 46.7 54.7 5.7 35.8 37.8 16.5 12.5 97.8 38.1 45.6 80.3 80.3 179.6 26.3 30.2 57.2 43.1 48.0 2.2 113.3 121.9 50.3 43.8 25.1 43.7 37.4 51.0 33.6 123.5 16.8 2.0 52.0 30.5 56.2 49.5 38.5 33.5 49.7 58.7 0.0 110.5 30.2 61.8 0.5 4.4 94.8 46.9 29.3 47.9 125.7 66.4 51.7 27.6 19.2 39.5 36.2 48.3 45.8 23.2 51.7 41.5 111.5 43.8 37.5 49.5 73.6 KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 70.7;Exocrine glandular cells: 38.2;Extravillous trophoblasts: 39.9;Proximal tubular cells: 35.6;Syncytiotrophoblasts: 83.5;Theca cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoli, Cytokinetic bridge" "HPA026538: AB_1852076, HPA027168: AB_1852078" "prognostic favorable (3.19e-5)" "unprognostic (3.36e-3)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.86e-4)" "unprognostic (2.61e-1)" "unprognostic (3.61e-3)" "unprognostic (2.11e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" "prognostic favorable (5.02e-6)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.78e-1)" 19.3 22.5 8.3 16.0 9.3 13.4 29.8 10.0 12.2 18.0 12.3 19.9 22.6 21.3 21.7 26.5 18.3 20.0 11.3 9.4 9.5 30.5 27.4 15.4 22.1 8.5 9.5 25.7 30.0 33.4 15.2 22.7 9.2 21.1 21.7 11.0 20.5 22.1 10.6 18.8 17.4 15.7 8.7 17.6 22.7 9.9 8.7 21.6 26.2 10.0 23.7 24.6 14.9 8.9 55.1 11.1 52.2 18.0 19.1 51.2 46.4 31.7 57.2 39.8 49.4 15.6 18.9 35.6 23.8 23.8 27.3 15.7 15.6 25.6 57.7 22.7 21.3 32.4 9.8 26.8 61.8 45.6 8.5 44.9 25.2 29.0 50.1 26.8 37.0 41.0 41.5 19.0 37.9 17.8 48.0 21.6 31.0 42.5 10.3 49.3 36.2 19.2 87.0 49.2 38.9 45.6 44.4 60.0 29.1 31.8 33.3 13.9 27.7 17.5 11.4 55.5 23.1 23.7 13.6 23.6 8.4 19.5 14.7 8.3 12.1 7.5 8.0 7.7 11.1 8.6 10.6 9.5 16.3 8.9 10.6 9.3 8.8 11.3 10.2 5.9 16.3 8.3 8.3 9.3 10.0 12.2 9.4 9.5 8.5 9.5 9.2 8.7 8.7 8.9 10.6 12.8 11.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 13.7 0.0 0.0 8.1 12.9 0.0 70.7 13.1 0.0 25.4 34.4 0.0 12.7 14.1 4.6 0.0 0.0 0.0 38.2 39.9 10.1 0.0 14.3 5.1 17.5 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 25.2 0.0 0.0 1.8 0.0 0.0 35.6 3.6 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 83.5 7.6 43.3 0.0 0.0 L3MBTL1 "dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3" ENSG00000185513 "L3MBTL histone methyl-lysine binding protein 1" Q9Y468 20 43489442-43550954 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 24.4;Oligodendrocyte precursor cells: 31.2;Oligodendrocytes: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SuSa: 5.1" HPA059648 Supported "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " "unprognostic (2.32e-1)" "unprognostic (2.77e-1)" "unprognostic (5.66e-2)" "unprognostic (7.19e-3)" "unprognostic (1.28e-1)" "unprognostic (1.50e-2)" "unprognostic (7.65e-4)" "unprognostic (6.02e-2)" "unprognostic (6.00e-2)" "unprognostic (2.23e-2)" "unprognostic (1.15e-3)" "unprognostic (1.20e-2)" "unprognostic (1.44e-3)" "unprognostic (2.01e-1)" "unprognostic (1.65e-1)" "unprognostic (2.89e-1)" "unprognostic (1.56e-4)" 2.7 4.8 8.6 0.8 8.5 0.8 3.9 6.4 10.2 6.4 6.1 6.1 1.1 5.0 2.0 4.2 6.9 0.6 3.9 8.0 9.4 5.9 2.0 3.0 0.8 8.0 8.8 7.5 3.3 1.1 16.7 0.6 8.7 6.4 0.7 3.4 4.6 1.7 5.1 3.9 4.8 0.8 6.1 5.5 3.9 10.1 10.8 0.8 6.9 1.1 0.5 4.8 6.4 7.6 0.1 0.1 1.6 0.9 0.1 0.0 2.6 0.2 0.3 0.5 0.4 0.2 1.7 0.9 0.4 0.9 0.5 1.1 0.0 0.4 0.3 0.0 1.1 0.3 1.4 2.1 0.3 0.0 0.3 0.3 0.6 0.1 0.0 2.9 0.3 0.9 0.6 0.2 0.1 0.3 0.4 1.2 1.0 0.7 1.4 0.6 0.2 0.5 1.2 0.4 0.4 1.3 0.5 0.5 0.1 5.1 0.6 1.7 0.6 0.2 1.1 0.0 0.4 1.0 0.4 0.3 1.5 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.2 8.6 8.5 6.4 10.2 8.0 9.4 8.0 8.8 8.7 6.1 10.8 7.6 1.2 3.2 3.2 16.0 3.3 0.9 2.0 1.9 8.0 17.2 2.7 2.8 1.9 1.5 4.2 5.5 14.6 2.1 5.2 0.9 1.9 1.3 2.0 2.4 2.6 2.2 1.2 1.7 12.4 0.2 3.3 1.9 2.0 1.8 5.1 8.3 1.8 0.6 1.4 6.7 24.4 2.1 4.1 1.6 1.8 2.8 5.0 2.0 3.6 4.7 1.0 4.7 4.1 31.2 25.4 0.8 1.9 6.0 1.7 2.5 3.1 0.7 6.6 10.8 0.0 4.2 2.8 13.9 12.3 1.5 1.1 1.9 2.3 4.6 1.8 1.4 L3MBTL3 KIAA1798 ENSG00000198945 "L3MBTL histone methyl-lysine binding protein 3" Q96JM7 6 130013699-130141449 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 63.5;HUVEC TERT2: 62.5;TIME: 43.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044382, HPA053035" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA044382: AB_2678920, HPA053035: AB_2682021" "unprognostic (2.33e-1)" "unprognostic (9.92e-2)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (4.22e-3)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.48e-2)" "unprognostic (2.90e-1)" "unprognostic (2.63e-1)" "unprognostic (7.56e-3)" "unprognostic (1.07e-1)" "unprognostic (8.44e-2)" "unprognostic (3.94e-3)" "unprognostic (2.88e-1)" "unprognostic (2.45e-2)" "unprognostic (1.60e-2)" 4.5 11.0 3.3 9.9 3.3 7.7 4.7 1.7 3.6 9.5 9.6 4.6 2.8 11.2 11.7 2.3 5.5 5.3 2.4 4.1 3.8 4.8 5.8 4.0 11.1 2.5 3.1 10.1 2.3 5.6 5.5 5.7 2.4 7.0 5.0 2.1 4.9 6.2 2.5 2.7 5.1 8.3 2.5 12.6 3.3 7.6 4.5 7.7 6.0 2.1 8.9 5.7 5.3 2.6 1.7 6.5 15.2 2.4 10.4 13.4 3.1 7.8 15.9 3.0 5.5 8.0 8.1 2.7 11.0 9.9 9.3 6.5 8.7 13.6 4.6 6.1 8.8 18.3 3.2 2.0 5.2 10.8 63.5 8.8 9.6 3.6 10.2 15.1 62.5 8.3 13.3 7.1 7.7 0.7 23.2 1.9 7.0 1.7 3.3 8.7 4.2 0.0 9.8 2.5 0.5 2.0 2.9 0.7 6.1 18.2 16.4 9.3 43.0 5.1 6.9 0.9 5.3 1.4 0.1 4.7 2.5 4.5 5.2 8.2 4.9 4.8 3.7 5.5 3.2 10.7 3.5 4.7 1.9 13.4 3.2 4.1 4.9 2.1 22.7 14.8 5.9 1.0 3.3 3.3 1.7 3.6 4.1 3.8 2.5 3.1 2.4 2.5 4.5 2.6 9.1 3.2 6.5 6.5 20.5 5.1 5.1 2.4 10.2 4.2 5.3 2.8 3.9 1.5 3.8 9.2 2.1 13.4 20.7 2.8 1.9 5.6 24.2 6.1 12.8 9.4 3.6 5.0 20.8 5.4 7.1 7.3 4.6 16.1 40.4 24.7 8.9 6.3 4.0 0.0 10.5 9.3 6.1 8.2 4.0 3.1 9.6 9.5 1.8 11.2 12.9 5.3 13.4 15.6 8.5 10.9 5.2 6.0 5.2 4.7 0.5 5.9 4.1 0.7 6.6 11.2 8.6 5.8 7.6 4.0 4.4 6.2 15.6 9.5 5.0 5.5 LACTB2 CGI-83 ENSG00000147592 "Lactamase beta 2" Q53H82 8 70635318-70669185 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.0" "Cell type enhanced" "Detected in all" "Early spermatids: 286.3;Proximal tubular cells: 325.7;Spermatocytes: 263.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 437.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044391, HPA053040" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 37000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "HPA044391: AB_10965168, HPA053040: AB_2682022" "unprognostic (6.33e-3)" "unprognostic (3.13e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-2)" "unprognostic (1.82e-1)" "unprognostic (4.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.34e-1)" "unprognostic (8.10e-2)" "unprognostic (3.95e-1)" "unprognostic (7.73e-3)" "unprognostic (1.96e-1)" "prognostic favorable (5.60e-4)" "unprognostic (3.70e-1)" "unprognostic (7.49e-2)" "unprognostic (2.93e-1)" "unprognostic (5.93e-2)" 20.4 39.3 6.4 12.9 8.0 3.2 18.4 8.4 9.0 10.8 8.7 21.9 38.8 9.6 11.5 10.2 9.3 28.7 29.8 5.8 8.3 77.0 96.0 20.1 15.6 8.1 7.9 10.0 14.8 21.0 8.3 10.6 8.9 15.4 21.3 12.7 15.0 9.2 28.2 12.4 33.8 15.7 8.1 11.5 16.0 63.2 7.6 14.5 20.2 32.1 13.5 13.2 7.9 10.6 65.7 66.4 20.8 8.6 35.6 53.7 12.5 36.0 20.7 37.7 28.2 32.3 72.3 0.1 14.4 17.4 75.7 45.9 25.0 38.0 30.2 38.8 26.6 30.5 8.1 18.0 74.0 30.1 25.5 64.6 44.8 18.6 28.2 18.0 10.0 23.2 53.4 60.1 50.6 19.6 17.1 5.5 22.3 88.2 60.3 15.2 12.1 14.0 146.3 33.8 29.6 10.3 79.7 437.8 41.0 27.0 72.7 40.1 16.0 3.0 20.8 67.4 29.4 47.7 38.1 0.2 21.1 50.6 28.7 15.8 13.8 13.0 8.5 16.8 10.6 12.6 8.8 8.4 17.3 11.7 8.3 9.2 5.8 11.0 16.7 11.9 13.4 5.9 6.4 8.0 8.4 9.0 5.8 8.3 8.1 7.9 8.9 8.1 7.6 10.6 15.1 57.7 45.1 3.6 16.0 16.4 22.1 58.9 12.5 15.4 12.1 15.1 38.4 18.6 43.9 18.4 8.4 25.1 12.0 27.2 76.3 51.2 286.3 29.4 11.7 15.3 12.1 19.6 3.9 117.2 15.3 15.1 20.4 31.5 9.5 8.7 19.2 76.1 48.0 8.4 4.6 25.8 34.6 34.5 11.2 40.9 20.5 24.2 16.0 3.7 19.4 35.3 8.2 2.5 10.3 70.2 25.1 15.1 18.3 16.0 59.8 325.7 44.9 14.7 6.6 9.6 14.4 263.1 25.0 12.4 16.8 19.4 13.9 34.2 34.7 11.0 LAMP5 "BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46" ENSG00000125869 "Lysosomal associated membrane protein family member 5" Q9UJQ1 20 9514358-9530524 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.6;retina: 29.6" "Cell type enhanced" "Detected in many" "dendritic cells: 78.4;Granulosa cells: 22.2;Horizontal cells: 60.6;Inhibitory neurons: 38.9;Theca cells: 23.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "plasmacytoid DC: 141.3" "Lineage enriched" "Detected in many" 31 "dendritic cells: 141.3" "Cell line enhanced" "Detected in some" "Karpas-707: 469.4;SH-SY5Y: 86.4;THP-1: 169.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004802, HPA070765" Enhanced Uncertain "Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Mitotic spindle, Centriolar satellite" "HPA004802: AB_10603682, HPA070765: AB_2686309" "unprognostic (2.78e-2)" "unprognostic (3.90e-3)" "unprognostic (5.73e-4)" "unprognostic (5.47e-2)" "unprognostic (7.89e-2)" "unprognostic (2.67e-1)" "unprognostic (3.80e-3)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (6.46e-6)" "unprognostic (5.12e-3)" "unprognostic (3.74e-2)" "unprognostic (1.08e-2)" "unprognostic (4.49e-3)" 0.5 4.3 41.7 1.5 96.6 2.3 0.9 11.0 51.8 8.8 3.7 2.2 1.2 4.8 6.3 0.4 10.6 3.1 0.4 39.1 14.3 0.8 0.2 0.9 5.7 47.7 10.1 21.9 1.2 0.7 6.3 0.1 43.7 2.3 1.2 29.6 1.1 3.8 0.1 0.7 1.3 3.9 29.1 1.8 1.4 0.9 35.3 1.4 0.9 0.2 5.2 0.7 1.2 13.6 0.1 0.2 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 469.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 86.4 0.0 0.0 0.1 0.4 0.0 169.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 21.1 0.3 4.2 1.7 0.0 0.0 0.3 0.2 4.5 0.0 0.1 9.5 0.5 0.0 0.0 0.4 0.0 0.0 141.3 0.0 2.4 41.7 96.6 11.0 51.8 39.1 14.3 47.7 10.1 43.7 29.1 35.3 13.6 0.5 0.0 1.1 6.2 3.4 0.1 0.0 0.0 0.0 12.3 0.3 4.3 0.3 0.0 0.0 0.0 8.4 0.0 78.4 0.0 0.0 0.8 5.4 0.2 0.7 0.8 0.0 0.0 10.0 0.0 0.0 8.4 0.0 0.7 0.0 22.2 0.0 0.0 1.3 60.6 38.9 0.0 0.0 0.6 0.8 7.5 0.6 3.5 3.6 4.7 5.4 3.9 0.0 13.0 1.5 0.4 0.0 0.0 5.5 0.5 0.0 0.0 0.0 5.7 0.0 0.3 13.9 0.6 1.1 0.0 0.0 0.0 0.9 23.2 0.1 0.0 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577198-17607972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 230.6;Hofbauer cells: 262.1;Proximal tubular cells: 274.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Supported Nucleoplasm,Midbody,Cytosol Yes No 3500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Nucleoplasm, Midbody" "HPA029606: AB_10599288, HPA029607: AB_10611381" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (4.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.28e-2)" "unprognostic (3.06e-1)" "unprognostic (8.79e-2)" 92.8 52.6 33.0 131.4 34.8 59.2 60.3 39.0 42.9 30.7 31.4 60.3 78.3 34.4 25.4 44.6 45.4 67.3 65.0 31.8 36.3 106.3 190.4 100.6 150.4 46.3 37.7 24.0 30.9 61.0 22.1 70.9 42.2 36.7 62.0 20.0 67.7 31.0 68.1 40.3 61.3 76.2 45.6 94.1 55.3 43.8 41.9 56.8 46.4 63.8 94.3 82.8 25.3 42.9 51.7 44.4 41.6 39.4 80.5 97.9 0.4 79.6 89.1 282.3 340.3 81.4 96.1 202.0 51.7 61.6 167.9 31.3 157.7 56.3 106.7 77.7 45.2 112.1 47.3 107.6 94.1 102.3 69.2 100.0 35.3 92.7 48.6 32.3 99.7 52.2 110.6 139.9 67.6 55.6 91.9 139.5 87.1 96.3 83.9 139.8 39.8 102.7 73.5 59.6 61.4 50.2 72.9 44.4 161.1 57.3 37.9 39.1 65.2 71.3 48.5 76.1 140.6 127.7 208.8 172.7 96.3 167.2 70.8 43.1 200.6 44.7 33.7 210.0 31.0 32.7 31.2 36.3 204.6 23.5 26.7 28.3 28.1 54.0 158.1 116.6 60.2 135.8 33.0 34.8 39.0 42.9 31.8 36.3 46.3 37.7 42.2 45.6 41.9 42.9 230.6 28.9 49.6 10.7 34.4 22.0 26.1 60.1 21.6 8.1 53.5 41.7 48.9 18.6 44.1 27.6 2.1 35.9 68.3 44.2 117.4 68.6 100.5 67.3 45.7 129.7 16.3 31.7 6.4 109.2 54.7 42.0 29.6 40.7 64.1 29.4 71.0 95.5 262.1 6.7 9.6 35.6 42.7 92.1 50.5 31.7 23.0 141.9 42.7 18.7 195.0 103.8 28.8 9.5 21.2 53.3 31.8 35.0 71.2 26.9 52.4 274.0 92.5 15.4 32.9 31.3 57.8 95.7 13.7 32.5 22.9 55.7 42.4 80.7 45.6 27.1 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LARP1 "KIAA0731, Lar1, LARP, Lhp1, MGC19556" ENSG00000155506 "La ribonucleoprotein 1, translational regulator" Q6PKG0 5 154712843-154817605 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015222, HPA051397, HPA054819" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 12000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB015222: , HPA051397: AB_2681467, HPA054819: AB_2682612" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (7.69e-2)" "unprognostic (1.76e-3)" "unprognostic (3.95e-2)" "unprognostic (3.08e-3)" "unprognostic (2.72e-2)" "unprognostic (3.34e-3)" "unprognostic (4.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.70e-1)" "unprognostic (6.83e-2)" "unprognostic (2.07e-1)" "unprognostic (2.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" 42.5 50.0 30.9 36.5 28.4 37.0 36.4 12.2 44.8 38.4 15.8 38.4 33.8 43.6 37.4 51.6 39.9 29.3 48.6 34.3 25.8 40.0 36.7 34.8 41.1 26.7 40.3 45.0 103.0 70.3 39.8 37.9 47.2 31.3 34.6 32.1 57.4 32.9 78.8 45.4 37.7 38.7 5.4 35.7 44.0 38.2 27.6 42.1 53.8 46.4 44.8 38.0 40.0 37.4 93.3 140.3 107.6 124.1 93.3 73.1 103.1 99.0 101.8 114.7 110.0 218.1 116.8 252.2 128.0 127.5 168.5 92.9 196.1 185.9 135.7 83.4 94.1 187.1 143.8 106.1 117.6 250.6 81.2 91.2 108.4 144.5 185.2 66.4 103.9 114.0 149.2 180.2 111.9 102.9 156.5 100.0 107.3 89.8 60.5 158.8 97.5 120.5 74.1 120.7 180.7 93.5 132.2 215.4 112.3 112.9 126.0 119.0 130.4 140.3 83.0 106.2 170.3 136.8 126.0 219.5 92.1 134.8 99.1 2.2 2.4 0.7 2.6 3.0 3.3 2.5 3.0 3.0 2.4 3.3 2.5 2.6 1.4 5.9 5.6 3.9 2.1 1.7 30.9 28.4 12.2 44.8 34.3 25.8 26.7 40.3 47.2 5.4 27.6 37.4 37.6 44.8 33.8 67.9 37.2 78.3 39.7 38.0 34.7 64.4 45.1 33.0 104.4 50.1 33.7 40.5 37.5 43.7 35.3 45.1 29.4 42.2 14.4 70.1 70.6 48.8 43.9 73.4 72.0 82.5 35.2 46.2 46.9 65.5 17.2 63.2 47.8 66.9 57.9 87.5 92.5 49.6 18.3 53.3 42.6 12.1 69.6 43.6 37.4 46.9 49.1 26.5 33.0 47.7 69.5 62.1 37.7 80.1 47.3 75.2 53.0 50.1 46.5 38.7 13.1 63.6 39.4 56.2 40.5 54.6 84.5 23.9 34.6 71.6 68.8 53.6 LAS1L "FLJ12525, Las1" ENSG00000001497 "LAS1 like ribosome biogenesis factor" Q9Y4W2 X 65438549-65534810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044431, HPA061463" Supported Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Centriolar satellite, Cytosol" "HPA044431: AB_10965695, HPA061463: AB_2684530" "unprognostic (9.71e-2)" "unprognostic (1.62e-3)" "unprognostic (1.57e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-2)" "unprognostic (2.38e-1)" "unprognostic (7.15e-3)" "unprognostic (2.83e-2)" "unprognostic (3.16e-1)" "unprognostic (2.76e-2)" "unprognostic (2.14e-1)" "unprognostic (5.06e-2)" "unprognostic (6.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.17e-3)" "unprognostic (2.00e-3)" "unprognostic (1.53e-1)" 21.5 19.1 36.9 11.4 37.8 16.0 21.2 35.6 53.7 27.1 34.0 26.4 5.8 23.1 6.8 20.0 25.5 6.3 18.6 34.8 34.8 19.1 19.6 17.4 13.1 36.3 37.1 29.9 21.2 12.2 17.5 8.9 36.8 22.7 8.1 9.4 18.8 11.9 19.3 25.4 18.5 10.3 38.1 22.5 20.0 33.6 37.1 12.8 20.5 6.3 14.0 24.2 21.4 37.8 44.1 63.6 36.3 28.5 12.4 16.1 29.1 28.5 14.9 42.8 36.4 30.4 31.3 95.0 31.3 17.8 28.7 31.3 63.9 39.6 50.6 25.6 52.3 32.2 53.2 32.4 16.6 95.9 26.8 17.8 28.7 40.5 25.6 15.1 26.0 46.1 80.3 71.3 25.5 51.8 62.4 53.6 52.6 49.8 63.1 56.2 67.4 79.9 24.7 17.9 24.6 32.9 51.3 26.0 20.1 25.8 19.5 44.6 22.2 26.4 50.9 73.2 44.4 23.7 37.7 94.6 28.1 92.5 13.6 17.7 17.7 11.2 20.1 24.0 21.3 23.9 18.6 23.5 24.2 26.4 23.2 19.8 2.0 22.9 19.3 19.1 21.7 21.0 36.9 37.8 35.6 53.7 34.8 34.8 36.3 37.1 36.8 38.1 37.1 37.8 15.5 12.8 22.3 23.2 21.6 18.2 21.4 24.8 9.1 34.9 12.7 13.6 9.2 21.5 27.0 3.7 29.2 32.8 13.3 6.9 15.6 27.9 58.0 17.5 20.0 17.2 16.7 18.1 19.6 26.6 31.4 16.8 11.7 12.9 18.3 26.0 8.9 14.8 16.3 45.4 17.7 9.4 18.3 8.5 13.4 148.2 17.4 11.7 10.6 8.4 18.1 16.1 12.3 13.0 12.5 21.4 7.7 15.4 26.3 23.5 10.2 14.3 26.7 34.2 13.1 21.8 22.8 24.1 19.1 17.8 18.6 17.8 17.5 22.3 14.1 14.8 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LAX1 "FLJ20340, LAX" ENSG00000122188 "Lymphocyte transmembrane adaptor 1" Q8IWV1 1 203765177-203776372 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 21.2" "Cell type enhanced" "Detected in some" "dendritic cells: 23.2;granulocytes: 82.2;NK-cells: 30.9;Plasma cells: 65.1;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 14 "B-cells: 7.5;NK-cells: 5.2;T-cells: 12.0" "Group enriched" "Detected in some" 4 "Karpas-707: 22.8;U-266/70: 28.2;U-266/84: 71.9;U-698: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002461, HPA003887, CAB025358" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB025358: , HPA002461: AB_1079239, HPA003887: AB_1079240" "unprognostic (2.85e-3)" "unprognostic (3.83e-3)" "unprognostic (3.90e-4)" "unprognostic (3.65e-2)" "unprognostic (5.22e-2)" "unprognostic (1.03e-5)" "unprognostic (2.99e-2)" "unprognostic (4.91e-2)" "unprognostic (4.36e-2)" "unprognostic (3.31e-3)" "unprognostic (4.77e-1)" "unprognostic (4.36e-1)" "unprognostic (4.23e-4)" "unprognostic (3.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" 0.5 0.6 0.2 8.8 0.3 1.6 1.7 0.4 0.4 1.4 0.3 3.7 3.1 0.3 0.3 0.9 0.4 2.6 0.3 0.3 0.2 0.2 0.9 2.7 11.8 0.5 0.2 0.2 0.4 0.1 0.0 0.1 0.5 0.7 3.4 0.1 1.2 0.4 0.1 0.2 2.0 0.7 0.2 7.2 4.5 0.3 0.3 11.1 0.2 0.3 21.2 5.1 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 8.0 0.2 22.8 0.0 0.0 8.7 0.0 0.1 0.0 0.0 2.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 28.2 71.9 24.9 0.0 1.9 0.0 0.3 0.0 0.5 12.0 0.0 9.1 7.5 7.1 9.4 0.0 2.5 5.5 7.1 0.3 5.2 0.0 0.0 8.1 3.5 0.2 0.3 0.4 0.4 0.3 0.2 0.5 0.2 0.5 0.2 0.3 0.7 0.9 0.0 1.9 0.0 14.6 1.1 0.4 0.0 0.0 0.0 0.3 0.1 2.6 0.0 0.6 0.0 0.0 0.1 23.2 0.1 0.0 0.2 0.0 0.4 0.4 0.5 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.4 82.2 0.0 2.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 1.2 0.0 0.0 1.9 10.6 0.0 0.4 0.0 30.9 0.5 0.0 0.1 0.0 0.0 65.1 0.4 0.6 0.1 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.2 0.4 0.0 29.2 0.1 0.3 0.5 LBX1 "HPX6, LBX1H" ENSG00000138136 "Ladybird homeobox 1" P52954 10 101226195-101229794 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skeletal muscle: 26.5" "Cell type enriched" "Detected in single" 5 "Skeletal myocytes: 3.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebellum: 1.9;medulla oblongata: 3.5;pons: 2.5;spinal cord: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 3.4;RH-30: 4.3;SCLC-21H: 9.1" "Group enriched" "Detected in some" 24 "cerebellum: 1.6;pons and medulla: 3.0" "Group enriched" "Detected in some" 18 "cerebellum: 1.2;medulla oblongata: 2.0;spinal cord: 2.0" "HPA002016, HPA002086, CAB079927" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB079927: , HPA002016: AB_2666518, HPA002086: AB_1079242" "unprognostic (4.13e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" "unprognostic (2.29e-1)" "unprognostic (7.28e-3)" "unprognostic (3.31e-1)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.4 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.3 0.0 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.5 0.4 2.5 4.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDB3 "CMD1C, KIAA0613, PDLIM6, ZASP" ENSG00000122367 "LIM domain binding 3" O75112 10 86668507-86736072 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 1423.0;skeletal muscle: 2945.6;tongue: 1809.4" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 1825.0" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.7;melanoma: 2.5;prostate cancer: 3.6;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 3.0;hTERT-RPE1: 3.3;SCLC-21H: 4.9;SK-MEL-30: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048955 Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 750000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA048955: AB_2680568" "unprognostic (1.60e-1)" "unprognostic (9.01e-2)" "unprognostic (4.87e-2)" "unprognostic (6.92e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-2)" "unprognostic (7.61e-2)" "unprognostic (2.54e-3)" "unprognostic (3.55e-2)" "unprognostic (4.72e-4)" "unprognostic (3.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.16e-1)" 11.1 1.4 12.8 2.8 39.6 0.4 6.5 29.8 29.0 10.1 0.1 36.2 2.4 15.1 4.9 54.5 17.3 3.1 1423.0 14.7 23.3 2.0 0.8 5.1 0.5 55.5 36.9 6.4 1.3 0.5 2.4 2.7 46.2 38.1 5.3 0.7 20.8 25.2 2945.6 4.8 8.8 23.7 26.4 0.6 9.0 4.7 38.4 0.7 5.2 1809.4 0.3 7.0 10.3 78.4 0.1 0.1 0.2 1.7 0.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.4 0.7 0.0 0.0 0.0 0.9 3.0 0.2 0.0 0.0 3.3 0.0 0.3 0.1 1.0 0.0 0.8 0.2 0.1 0.2 0.2 0.2 0.0 1.1 0.0 0.0 0.6 4.9 0.9 0.2 0.1 2.4 0.7 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 39.6 29.8 29.0 14.7 23.3 55.5 36.9 46.2 26.4 38.4 78.4 1.5 0.0 0.0 1.0 0.0 1.0 0.5 0.2 0.0 1.5 0.2 0.3 1825.0 0.0 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.0 23.4 0.1 0.4 15.5 0.0 0.0 4.5 1.1 0.0 31.5 0.0 0.2 0.0 0.9 0.0 0.0 0.1 0.0 2.6 0.0 4.1 0.0 1.2 19.6 11.1 0.5 1.8 1.9 0.0 0.7 0.0 1.5 245.1 0.1 0.0 6.8 0.0 0.3 0.0 0.1 0.1 4.1 39.5 48.0 54.9 1.0 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 LEO1 ENSG00000166477 "LEO1 homolog, Paf1/RNA polymerase II complex component" Q8WVC0 15 51938025-51971778 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 7 "granulocytes: 272.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040741, HPA040941" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Centrosome" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nucleoli fibrillar center" Centrosome "HPA040741: AB_10794859, HPA040941: AB_10805832" "unprognostic (2.76e-2)" "unprognostic (2.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.81e-3)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (2.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (8.48e-2)" "unprognostic (2.10e-2)" "unprognostic (1.08e-1)" 10.2 11.4 8.1 13.8 8.8 9.0 15.5 14.7 12.9 11.6 6.4 17.0 13.3 10.4 10.0 19.8 8.7 13.2 8.1 8.0 10.0 13.7 22.2 9.7 18.0 8.0 8.1 8.5 8.1 18.8 9.1 12.1 7.7 12.3 19.2 12.0 18.5 8.6 13.9 20.8 14.5 11.7 6.9 10.5 13.2 9.3 8.3 22.1 11.1 11.7 17.9 19.3 14.0 10.0 28.0 63.9 40.3 32.6 40.7 35.0 28.8 44.4 36.6 37.3 33.9 44.3 17.9 56.2 25.3 45.8 41.3 53.2 54.2 39.6 35.8 37.5 24.5 88.5 50.6 78.5 32.0 80.7 118.2 37.9 30.5 29.2 37.6 35.2 37.0 46.5 54.6 30.1 44.9 118.7 43.0 61.1 17.4 82.6 27.0 47.6 69.7 58.9 32.8 77.0 28.5 43.4 33.9 51.5 36.5 43.8 42.8 72.6 44.4 36.8 25.5 34.3 53.7 23.4 78.2 50.7 32.2 113.1 40.0 11.5 14.5 15.7 27.4 23.3 25.7 18.7 27.2 22.3 23.8 16.4 27.9 25.2 3.3 30.9 26.0 17.8 31.7 16.3 8.1 8.8 14.7 12.9 8.0 10.0 8.0 8.1 7.7 6.9 8.3 10.0 16.2 35.3 24.6 10.1 15.2 26.1 16.8 33.4 18.2 38.2 11.8 10.2 21.2 17.2 37.0 7.3 10.4 24.9 24.8 24.6 15.6 26.3 2.4 19.5 38.8 18.0 7.7 12.4 16.5 24.2 26.7 19.9 15.8 29.8 272.8 16.2 10.0 18.0 19.5 26.9 16.9 17.9 26.4 14.8 6.0 2.7 8.1 13.0 3.6 5.6 12.8 23.1 22.6 13.0 13.3 18.2 14.7 13.5 11.0 9.0 20.5 23.3 31.4 23.2 6.6 18.5 29.3 21.5 11.0 19.5 24.7 17.6 25.0 23.8 17.0 21.2 LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 76.9;Late spermatids: 57.6;Pancreatic endocrine cells: 48.6;Spermatocytes: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.2;hTERT-HME1: 26.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 24.0" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" 1.2 1.0 3.4 1.1 3.6 5.3 0.7 5.7 4.9 1.6 2.9 0.7 0.8 1.4 1.1 1.1 1.4 1.2 0.8 3.2 2.8 2.3 0.7 2.0 1.3 2.3 2.9 2.1 0.7 1.6 1.3 1.8 3.1 1.1 0.8 4.2 0.4 0.8 0.2 1.1 0.5 0.6 2.0 1.6 2.7 23.8 2.6 2.4 1.0 0.3 1.4 1.9 0.6 4.2 21.2 4.5 3.0 2.9 2.3 7.0 2.5 7.5 9.2 10.6 6.2 1.5 8.3 2.8 16.5 1.5 3.1 2.2 5.9 25.2 11.7 1.2 2.9 3.2 2.3 4.2 2.7 0.7 2.8 1.7 7.2 11.7 26.9 5.9 10.7 3.4 2.6 3.9 9.3 4.2 7.5 1.8 0.8 1.6 18.2 2.9 4.8 1.6 16.8 1.1 2.4 2.3 2.5 0.4 0.9 1.8 2.4 1.2 20.0 3.3 22.5 7.4 1.7 2.6 1.6 2.0 5.6 3.3 2.5 1.3 4.1 0.7 0.9 1.6 2.0 1.5 0.9 1.5 1.7 1.8 1.7 1.7 21.5 1.4 5.0 0.7 5.2 1.3 3.4 3.6 5.7 4.9 3.2 2.8 2.3 2.9 3.1 2.0 2.6 4.2 3.0 3.2 6.4 2.3 10.3 0.5 13.9 7.6 6.8 6.6 2.1 3.3 1.8 4.3 3.2 5.5 6.2 2.6 10.1 1.4 1.9 4.0 76.9 21.8 7.1 4.2 0.0 0.8 3.6 20.5 7.9 5.0 16.8 20.5 9.5 1.1 1.4 0.0 1.4 6.7 7.3 1.9 2.0 2.2 2.3 57.6 2.1 3.6 1.8 1.0 2.0 3.6 1.0 1.5 1.6 48.6 0.1 1.5 4.5 2.9 0.3 3.0 4.9 8.4 0.0 4.5 3.3 54.8 3.3 2.5 0.9 8.1 9.1 1.5 1.3 4.5 LETMD1 "HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2, SLC55A3" ENSG00000050426 "LETM1 domain containing 1" Q6P1Q0 12 51047962-51060424 "Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074361 Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Mitochondria "Nucleoplasm, Nucleoli" "HPA074361: AB_2686682" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.11e-1)" "unprognostic (2.20e-2)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "unprognostic (5.05e-2)" "unprognostic (7.86e-2)" "unprognostic (6.57e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.07e-1)" "unprognostic (7.79e-2)" "unprognostic (2.58e-1)" "prognostic favorable (3.16e-4)" 31.2 27.0 17.5 11.7 19.2 22.3 29.9 17.8 24.2 19.6 22.8 24.3 36.0 19.4 23.8 13.1 32.4 17.1 18.9 20.0 19.0 32.7 40.3 17.6 18.2 19.3 17.2 36.6 37.1 32.4 19.4 13.7 20.0 18.9 28.3 20.9 27.5 19.4 23.6 19.7 24.5 19.8 18.3 16.5 24.5 13.3 18.7 22.4 37.2 27.8 20.8 17.0 15.5 19.5 19.1 16.7 12.7 33.5 54.9 89.9 12.6 19.4 31.7 19.9 22.2 41.2 38.6 50.2 23.4 20.9 14.2 34.7 25.8 26.1 22.6 18.3 32.4 36.5 23.6 32.8 36.1 32.8 25.6 75.4 82.3 23.7 55.5 60.4 20.3 47.7 38.1 35.4 27.5 29.5 23.2 33.1 8.4 23.6 45.2 19.5 15.0 27.4 25.2 28.3 37.3 16.7 14.7 32.2 45.4 12.4 51.1 29.2 15.6 12.8 13.4 20.9 11.2 32.2 53.8 21.6 23.1 21.1 9.1 3.7 9.6 3.9 10.1 10.8 15.1 15.0 17.0 12.8 9.3 9.2 20.5 19.1 3.0 12.6 16.2 8.3 17.0 12.5 17.5 19.2 17.8 24.2 20.0 19.0 19.3 17.2 20.0 18.3 18.7 19.5 27.0 22.4 29.5 41.1 38.8 49.6 40.0 51.9 66.0 20.9 66.2 64.8 12.6 35.8 20.5 23.9 10.4 49.6 31.7 20.3 92.0 17.2 9.3 23.6 22.2 26.2 27.7 35.5 22.6 32.7 23.3 32.9 31.6 18.4 25.4 29.7 25.7 19.1 30.3 18.5 26.5 36.0 28.5 56.3 35.7 17.0 32.6 27.9 39.2 13.1 31.5 31.8 23.7 16.1 25.4 15.6 26.8 30.5 29.5 26.0 87.0 65.7 25.1 18.9 26.3 33.5 31.8 20.5 26.0 44.2 44.3 27.9 38.8 55.4 52.7 26.6 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LHFPL2 KIAA0206 ENSG00000145685 "LHFPL tetraspan subfamily member 2" Q6ZUX7 5 78485215-78770021 "Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 121.9;Microglial cells: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.9;plasmacytoid DC: 6.3" "Group enriched" "Detected in many" 9 "dendritic cells: 6.3;granulocytes: 7.9;monocytes: 3.9" "Cell line enhanced" "Detected in many" "GAMG: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042402, HPA076743" Uncertain Approved "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA042402: AB_10794276, HPA076743: " "unprognostic (2.19e-2)" "unprognostic (3.86e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.44e-3)" "unprognostic (2.32e-1)" "unprognostic (8.43e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.45e-7)" "unprognostic (3.40e-2)" "unprognostic (3.88e-2)" "unprognostic (1.34e-2)" "unprognostic (7.85e-2)" 18.2 18.8 10.9 19.6 11.5 18.4 20.5 12.0 13.4 14.0 15.3 17.7 23.8 18.0 18.9 6.3 9.1 22.6 12.2 10.1 11.1 3.1 6.4 19.7 15.2 17.2 13.7 18.5 11.4 10.4 5.7 14.8 14.9 11.4 17.5 5.5 19.3 24.7 2.7 5.7 21.2 22.0 14.6 4.3 14.8 9.1 18.5 14.8 9.1 4.1 14.4 36.3 10.3 18.7 9.8 36.1 10.6 14.1 63.0 18.0 32.7 11.0 28.0 18.7 32.5 12.8 28.4 24.4 4.8 21.7 116.4 16.6 10.2 11.8 30.6 0.2 9.1 24.3 7.2 21.6 46.5 0.1 0.2 20.7 46.6 57.3 88.4 29.6 44.8 0.9 0.2 17.8 42.9 5.2 0.1 1.4 11.8 7.9 10.3 4.7 15.0 6.8 7.1 42.6 2.0 14.4 17.9 6.6 62.5 22.3 3.9 3.0 29.8 21.7 11.8 60.1 33.2 0.7 0.1 34.1 57.5 0.2 39.7 7.9 3.9 4.0 0.0 1.4 0.1 0.6 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 0.5 6.3 0.1 1.3 10.9 11.5 12.0 13.4 10.1 11.1 17.2 13.7 14.9 14.6 18.5 18.7 13.5 3.2 3.4 20.2 5.7 8.7 7.3 5.2 0.6 6.6 18.2 15.6 3.7 1.5 7.6 7.3 0.0 4.0 20.3 34.8 0.0 9.1 1.5 7.5 26.3 21.4 2.4 10.7 15.8 12.9 2.6 38.1 10.7 14.6 0.0 121.9 35.3 1.4 60.1 3.3 7.9 16.3 6.1 40.4 14.7 1.7 19.3 36.3 10.6 209.9 5.5 5.4 0.0 55.3 4.6 17.0 16.1 33.4 3.3 10.4 29.8 0.7 3.9 2.2 6.6 19.1 13.1 0.7 1.7 1.4 4.8 7.3 1.3 22.1 10.0 12.4 LHX1 "LIM-1, LIM1" ENSG00000273706 "LIM homeobox 1" P48742 17 36936785-36944612 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "kidney: 10.7" "Cell type enriched" "Detected in some" 8 "Horizontal cells: 361.7" "Group enriched" "Detected in some" 4 "ovarian cancer: 8.1;testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.8;HMC-1: 1.6;WM-115: 7.0" "Region enhanced" "Detected in many" "cerebellum: 19.1" "Region enriched" "Detected in many" 4 "cerebellum: 15.7" "HPA044307, HPA073521, HPA074382" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA044307: , HPA073521: AB_2732226, HPA074382: " "unprognostic (3.86e-5)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.85e-2)" "unprognostic (1.06e-4)" "unprognostic (2.67e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (4.20e-3)" "unprognostic (1.74e-5)" "unprognostic (1.33e-1)" "unprognostic (8.62e-2)" "unprognostic (3.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.5 0.2 0.5 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.1 0.0 0.0 42.3 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 361.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 13.0 0.0 1.6 0.0 0.0 0.2 1.1 2.3 0.0 0.0 0.4 0.3 0.0 0.2 0.0 LHX5 ENSG00000089116 "LIM homeobox 5" Q9H2C1 12 113462033-113472280 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 5.0" "Cell type enhanced" "Detected in single" "Basal respiratory cells: 1.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053908 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Nuclear bodies" "HPA053908: AB_2682304" "unprognostic (5.20e-2)" "unprognostic (4.04e-3)" "unprognostic (1.73e-1)" "unprognostic (1.21e-1)" "unprognostic (2.19e-2)" "unprognostic (1.06e-2)" "unprognostic (1.95e-1)" "unprognostic (4.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" "unprognostic (5.10e-2)" "unprognostic (7.54e-3)" 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 5.0 1.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 0.1 0.0 1.9 5.0 1.5 1.7 1.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 LHX8 Lhx7 ENSG00000162624 "LIM homeobox 8" Q68G74 1 75128434-75161533 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.2;salivary gland: 2.7" "Group enriched" "Detected in some" 8 "Early spermatids: 1.2;Late spermatids: 1.4;Spermatocytes: 3.3;Spermatogonia: 3.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebral cortex: 6.2;hypothalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 25.6;U-266/70: 8.6" "Region enhanced" "Detected in many" "basal ganglia: 9.9" "Region enriched" "Detected in some" 5 "basal ganglia: 9.7" HPA071806 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" Cytosol "HPA071806: AB_2686449" "unprognostic (2.28e-2)" "unprognostic (6.23e-2)" "unprognostic (3.85e-3)" "unprognostic (1.52e-9)" "unprognostic (1.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.06e-2)" 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.6 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.2 1.3 1.7 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.3 0.0 0.0 8.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 6.2 0.0 6.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: AB_2677476, HPA048071: AB_2680248" "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavorable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 2.8 3.2 3.3 9.0 3.2 34.5 3.6 3.6 3.5 5.5 2.3 6.8 8.6 4.0 2.5 7.4 5.9 2.3 1.6 2.9 3.2 2.9 4.0 3.4 15.6 4.4 2.9 6.0 7.0 4.2 4.8 5.1 4.5 4.0 4.2 2.7 4.8 3.0 3.8 10.4 9.6 2.2 2.6 6.0 5.2 8.2 3.1 20.7 5.1 1.0 9.7 3.5 5.0 3.9 43.4 64.1 57.1 37.6 2.6 4.2 41.7 27.0 19.1 44.1 47.2 35.0 42.9 83.7 15.3 11.2 11.9 30.1 24.7 26.7 16.9 45.2 48.8 56.4 38.7 47.5 1.0 63.0 43.7 5.7 2.5 23.0 3.4 5.0 24.0 51.0 46.3 29.8 23.3 44.0 107.3 123.7 33.6 46.7 15.9 84.1 48.4 43.6 12.3 64.8 36.3 36.5 32.3 33.6 10.1 12.5 22.7 44.5 22.6 31.7 54.3 23.9 40.3 29.3 49.0 83.1 12.7 38.0 33.3 0.0 1.6 2.6 7.8 6.8 7.7 10.9 8.8 8.3 1.6 10.0 11.5 8.2 1.3 12.1 3.3 1.5 10.9 5.7 3.3 3.2 3.6 3.5 2.9 3.2 4.4 2.9 4.5 2.6 3.1 3.9 3.9 3.2 13.6 5.9 16.1 8.3 9.5 8.7 24.5 21.5 7.8 12.3 3.9 7.2 10.3 3.7 10.4 31.1 9.6 10.2 7.9 5.8 19.3 12.0 5.1 8.3 0.0 36.2 4.2 5.2 35.8 6.8 5.1 8.3 6.3 23.1 5.0 5.3 16.4 8.4 5.6 10.0 6.1 3.5 6.8 8.5 2.1 6.6 3.6 3.7 7.2 10.9 11.3 3.5 8.4 3.0 4.4 1.9 23.0 2.8 7.6 4.7 19.5 11.3 13.1 4.5 6.5 13.5 26.1 15.9 9.1 10.0 13.9 6.0 15.3 8.7 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LIN28A "CSDD1, FLJ12457, LIN-28, LIN28, ZCCHC1" ENSG00000131914 "Lin-28 homolog A" Q9H9Z2 1 26410817-26429728 "Predicted intracellular proteins" "RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 5.2" "Group enriched" "Detected in some" 43 "Early spermatids: 35.2;Late spermatids: 69.5" "Cancer enriched" "Detected in single" 261 "testis cancer: 101.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 861.2;SuSa: 300.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020785, HPA063074, HPA068814" Enhanced Supported "Nucleoli,Cytosol,Rods & Rings" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nucleoli, Rods & Rings" "CAB020785: , HPA063074: , HPA068814: " "unprognostic (9.64e-3)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.85e-1)" "unprognostic (2.21e-1)" "unprognostic (2.49e-2)" "unprognostic (1.83e-1)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" 0.0 0.0 0.1 0.0 0.2 0.2 0.0 1.1 0.3 0.0 0.4 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 5.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 84.3 0.5 0.0 0.0 62.7 0.1 0.0 0.0 0.0 2.0 0.5 0.0 0.1 0.0 0.0 0.2 11.6 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 861.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 300.9 27.2 0.2 0.1 0.4 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.2 1.1 0.3 0.1 0.2 0.2 0.3 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.2 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 69.5 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 1.1 0.4 1.2 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.2 LIN28B "CSDD2, FLJ16517" ENSG00000187772 "Lin-28 homolog B" Q6ZN17 6 104936616-105083332 "Predicted intracellular proteins" "RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 65.4" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 75.4;Early spermatids: 27.5;Excitatory neurons: 40.2;Extravillous trophoblasts: 83.0;Late spermatids: 25.2;Syncytiotrophoblasts: 55.8" "Cancer enriched" "Detected in single" 25 "testis cancer: 12.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 49.1;BEWO: 252.1;Hep G2: 44.0;K-562: 86.9;NTERA-2: 44.8;SuSa: 44.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA036630, HPA061745" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA036630: AB_10669911, HPA061745: AB_2684601" "unprognostic (2.00e-4)" "unprognostic (6.75e-2)" "unprognostic (2.02e-1)" "unprognostic (2.57e-2)" "unprognostic (1.59e-2)" "unprognostic (4.10e-2)" 0.1 0.1 0.4 0.0 0.8 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.3 65.4 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 4.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 3.2 49.1 10.0 0.0 0.0 252.1 0.1 0.0 0.0 0.0 16.6 0.1 0.1 0.0 0.1 3.0 0.1 31.2 0.0 0.0 0.0 24.1 36.6 0.0 44.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.9 1.2 0.0 0.0 5.6 6.2 44.8 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.1 11.6 0.1 0.3 4.0 44.5 0.0 10.6 1.0 0.1 5.3 0.2 0.1 14.8 22.6 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.8 0.0 1.3 0.6 0.7 0.4 0.2 0.1 0.0 0.3 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 6.2 75.4 0.0 0.0 0.0 0.0 27.5 0.0 0.0 8.3 0.0 0.0 40.2 0.0 83.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 9.7 1.7 5.7 0.0 0.0 0.0 0.0 25.2 0.3 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 6.6 0.0 0.0 6.3 9.9 0.0 0.0 55.8 0.0 0.0 0.0 0.0 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 701.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2578.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 2578.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Vesicles" "HPA006960: AB_1079254" "unprognostic (2.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.32e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.07e-2)" "unprognostic (8.75e-3)" "unprognostic (3.60e-1)" "unprognostic (6.15e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (5.01e-1)" "unprognostic (1.85e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" 139.3 43.7 53.5 165.8 81.9 207.0 95.5 79.6 70.0 121.2 70.5 121.1 46.3 100.5 77.8 62.7 108.2 114.1 63.9 52.2 63.0 182.3 107.7 192.1 112.3 94.0 79.4 67.6 64.6 56.5 39.0 71.3 92.7 105.9 116.1 63.9 116.4 83.4 36.3 71.6 57.9 93.5 77.3 119.6 70.7 10.6 77.6 68.6 116.8 37.6 123.7 214.1 83.1 109.4 79.2 157.8 89.4 43.8 13.9 11.0 90.7 100.2 309.0 93.6 139.1 62.6 206.3 39.9 126.8 86.1 108.7 95.5 40.1 186.4 88.4 304.2 45.8 2.8 117.1 310.3 212.9 12.5 12.9 35.0 320.8 79.6 210.7 84.4 0.3 2.7 25.3 149.5 1.5 75.8 1.8 183.3 146.4 104.0 0.6 12.1 19.6 228.2 79.0 110.4 22.2 68.0 172.9 219.4 183.9 136.3 122.5 66.7 0.8 38.7 65.3 23.0 24.2 59.2 140.6 100.5 45.1 95.8 225.5 508.8 149.5 284.0 459.6 130.2 277.2 174.0 284.0 412.7 178.0 173.9 318.9 381.4 2578.1 274.5 81.9 220.1 350.3 584.9 53.5 81.9 79.6 70.0 52.2 63.0 94.0 79.4 92.7 77.3 77.6 109.4 297.5 44.8 70.0 7.5 176.7 157.4 336.2 365.4 68.3 2.2 180.5 157.6 48.8 148.7 222.2 163.7 0.0 56.4 505.5 305.4 485.2 245.8 2.3 112.2 151.9 76.3 17.5 18.3 1.1 72.9 471.9 156.7 39.8 108.1 214.9 1.1 94.2 52.9 227.8 0.0 1.6 153.1 175.0 156.9 701.0 11.3 56.2 422.0 156.5 7.5 391.8 232.7 433.5 11.6 59.5 123.3 236.1 68.4 186.3 239.8 23.3 104.3 150.3 5.4 52.6 89.6 176.1 0.2 5.4 37.1 132.1 37.1 278.7 16.6 88.9 368.6 LIX1 "C5orf11, Lft" ENSG00000145721 "Limb and CNS expressed 1" Q8N485 5 97091867-97142753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 32.4;retina: 42.6" "Cell type enriched" "Detected in some" 13 "Muller glia cells: 289.4" "Cancer enhanced" "Detected in many" "glioma: 13.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Group enriched" "Detected in some" 13 "RPTEC TERT1: 53.5;SuSa: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA058426 Uncertain Approved "Vesicles,Cytokinetic bridge,Cytosol" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Vesicles, Cytokinetic bridge" "HPA058426: AB_2683715" "unprognostic (3.18e-1)" "unprognostic (4.53e-2)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (8.96e-2)" "unprognostic (6.60e-2)" "unprognostic (1.34e-1)" "unprognostic (4.70e-1)" "unprognostic (7.63e-2)" "unprognostic (1.58e-2)" "unprognostic (3.52e-1)" "unprognostic (2.01e-1)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" "unprognostic (9.61e-2)" 0.0 0.3 24.0 0.2 22.3 0.3 0.0 24.7 16.2 0.0 7.1 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 26.6 30.7 3.1 0.0 0.0 0.5 31.1 32.4 0.0 0.0 0.0 1.5 0.4 24.7 1.5 0.3 42.6 0.0 5.8 0.0 0.1 0.2 0.2 32.2 0.1 0.4 0.1 26.1 0.0 4.6 0.0 0.0 0.0 0.0 29.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 53.5 0.0 0.1 0.0 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 24.0 22.3 24.7 16.2 26.6 30.7 31.1 32.4 24.7 32.2 26.1 29.1 0.0 0.0 0.0 21.2 1.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.7 0.0 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 3.3 1.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 289.4 0.0 0.5 1.4 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 287.6;Ductal cells: 122.0;Endothelial cells: 161.9;Pancreatic endocrine cells: 114.1;Smooth muscle cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;HSkMC: 124.9;hTEC/SVTERT24-B: 93.8;U-2197: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" 131.4 14.3 9.5 45.6 9.5 0.1 97.5 13.5 10.8 27.2 38.8 18.1 9.0 90.3 18.4 36.1 57.8 67.2 90.6 14.0 9.7 33.0 9.7 131.7 17.3 14.0 11.0 65.8 37.7 30.0 8.7 54.5 12.1 34.8 7.0 15.2 42.2 16.8 573.4 28.8 20.1 63.3 13.2 55.6 46.4 11.3 12.6 4.7 18.5 260.9 10.2 110.6 31.5 14.8 9.4 52.0 8.6 6.6 62.0 34.6 8.9 37.9 19.4 20.5 50.0 38.8 11.5 0.0 4.2 44.2 8.8 0.8 4.9 9.9 8.4 16.0 3.6 11.6 3.5 7.6 88.9 0.0 1.1 124.9 0.2 93.8 0.7 11.9 10.1 0.0 0.0 0.0 26.8 6.7 0.0 0.1 16.8 12.0 2.3 0.2 28.2 0.1 19.1 3.6 0.3 21.3 6.4 31.1 20.6 23.9 40.7 0.1 5.0 20.4 40.3 83.0 25.9 5.1 6.2 2.6 4.1 2.9 27.0 0.0 0.0 0.0 0.0 0.4 0.1 2.0 2.9 0.6 3.3 0.3 0.0 0.1 0.0 0.0 0.0 1.0 20.5 0.3 9.5 9.5 13.5 10.8 14.0 9.7 14.0 11.0 12.1 13.2 12.6 14.8 287.6 9.6 10.7 2.0 2.1 31.6 42.1 7.4 9.6 13.0 20.4 17.0 14.7 14.3 13.5 5.5 10.4 3.9 1.7 1.4 3.9 122.0 1.1 9.6 77.7 161.9 12.1 0.0 0.8 48.5 4.2 64.5 7.1 4.8 10.2 44.2 30.7 12.6 3.4 97.6 1.2 2.4 4.1 0.8 47.0 2.3 11.5 3.2 53.4 29.0 9.0 38.9 1.0 4.0 8.7 114.1 0.9 32.4 8.0 8.4 0.3 45.5 12.0 8.0 0.0 57.0 112.9 6.4 9.1 29.0 27.1 4.4 5.3 21.5 4.7 7.5 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106862-98209638 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.7;Excitatory neurons: 114.9;Inhibitory neurons: 69.0;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 25.2" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: AB_2677698" "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 3.5 7.0 4.2 3.9 6.2 13.8 3.6 0.0 25.2 4.9 0.0 9.7 8.8 3.9 3.9 9.5 4.1 4.2 12.4 6.0 0.0 6.6 6.2 6.6 3.6 2.1 0.5 5.0 14.8 10.7 7.0 3.1 1.8 5.1 8.0 8.2 7.9 4.0 11.1 9.0 9.8 3.7 0.0 4.6 6.5 5.2 1.2 4.9 5.8 7.0 4.8 5.8 6.2 8.7 12.5 14.5 11.0 11.4 5.8 4.6 10.2 5.1 5.5 4.9 5.9 11.5 11.1 6.5 14.3 6.5 18.6 13.4 12.8 7.8 7.6 9.4 9.0 4.4 13.0 11.6 7.0 8.0 7.6 3.2 10.5 10.1 13.6 4.9 7.4 7.4 11.8 13.4 4.5 16.9 8.5 4.8 13.4 17.1 7.0 9.2 7.5 13.0 8.2 21.7 7.8 15.7 10.2 18.4 7.4 11.0 5.1 3.2 9.2 10.2 16.6 20.5 11.7 5.9 11.2 12.8 6.8 6.2 12.3 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.2 0.3 0.4 1.4 0.1 0.3 0.2 0.2 0.1 4.2 6.2 0.0 25.2 6.0 0.0 2.1 0.5 1.8 0.0 1.2 8.7 6.0 28.9 17.0 28.7 7.8 9.7 4.3 6.2 14.8 14.2 5.5 3.9 22.4 15.7 11.8 1.8 14.6 2.8 7.5 50.7 1.9 6.1 1.1 13.2 7.6 5.7 12.0 8.4 114.9 9.1 1.9 5.4 21.4 26.4 2.5 5.3 2.5 8.4 2.2 6.7 69.0 14.7 4.1 1.6 2.3 2.0 1.8 3.2 1.8 16.9 2.8 6.1 7.2 52.3 29.6 10.3 23.8 4.5 12.9 8.8 14.0 3.0 15.8 10.6 0.0 8.6 5.7 6.9 6.3 15.5 10.9 3.0 8.6 2.7 14.7 20.5 LMX1A "LMX1, LMX1.1" ENSG00000162761 "LIM homeobox transcription factor 1 alpha" Q8TE12 1 165201867-165356715 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 20.4" "Group enriched" "Detected in some" 16 "Early spermatids: 30.6;Enteroendocrine cells: 41.9;Late spermatids: 23.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA028051, HPA030088" Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA028051: AB_10599731, HPA030088: AB_10601106" "unprognostic (1.73e-1)" "unprognostic (9.57e-2)" "unprognostic (7.58e-2)" "unprognostic (1.59e-1)" "unprognostic (2.17e-1)" "unprognostic (2.82e-1)" "unprognostic (2.63e-1)" "unprognostic (3.22e-2)" "unprognostic (2.10e-3)" "unprognostic (1.51e-1)" "unprognostic (9.82e-3)" 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.3 20.4 0.3 1.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 1.3 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 3.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 1.3 2.5 0.0 0.1 1.0 0.0 0.2 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.7 1.3 0.2 2.1 0.5 0.0 2.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.6 0.2 0.0 0.1 41.9 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 23.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 LNP1 NP3 ENSG00000206535 "Leukemia NUP98 fusion partner 1" A1A4G5 3 100401532-100456319 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 46.1;testis: 29.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 50.1;Early spermatids: 147.6;Horizontal cells: 257.4;Spermatocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 4 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "PC-3: 18.7;U-266/84: 17.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 6.8;cerebral cortex: 8.7;hippocampal formation: 7.3;olfactory bulb: 5.0" HPA047926 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear speckles, Cytosol" "HPA047926: " "unprognostic (1.78e-1)" "unprognostic (3.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.40e-3)" "unprognostic (6.33e-3)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.66e-3)" "unprognostic (1.81e-1)" "unprognostic (1.75e-2)" "unprognostic (1.58e-2)" "unprognostic (1.74e-2)" "unprognostic (8.28e-3)" "unprognostic (1.43e-1)" "unprognostic (7.98e-2)" "unprognostic (2.11e-1)" "unprognostic (6.08e-2)" 2.2 1.9 5.1 0.8 5.9 0.1 1.9 5.3 6.1 2.6 3.0 2.5 0.6 3.1 6.7 1.3 3.0 2.0 8.5 5.2 6.0 4.3 7.7 3.1 0.9 5.2 5.1 3.9 3.3 1.7 6.1 2.7 6.4 1.9 1.5 46.1 2.0 2.3 2.9 0.7 1.2 2.7 4.6 1.2 1.5 29.0 4.7 1.3 3.6 2.1 1.1 3.1 1.7 5.3 3.2 1.7 9.9 0.9 4.1 2.9 0.7 2.0 6.3 2.7 2.8 0.9 0.9 2.4 0.9 1.9 2.8 2.1 1.8 3.2 2.9 2.6 2.1 7.1 0.5 4.0 1.8 5.4 0.8 3.5 0.8 1.2 5.0 2.5 0.3 1.0 2.7 11.6 2.1 2.7 6.2 4.3 7.6 2.1 18.7 4.6 5.4 6.1 1.9 0.4 9.5 4.9 1.6 2.7 4.5 2.3 0.6 0.6 0.7 1.0 10.4 1.0 2.2 14.9 17.3 9.5 3.3 3.3 2.1 0.0 0.0 0.0 0.4 0.0 0.9 0.3 0.3 0.2 0.2 0.1 0.4 0.4 0.0 0.1 0.0 0.0 1.4 0.1 5.1 5.9 5.3 6.1 5.2 6.0 5.2 5.1 6.4 4.6 4.7 5.3 0.9 0.0 0.5 4.2 1.8 1.0 1.3 0.7 2.2 42.2 2.2 1.9 10.5 0.0 1.5 1.8 50.1 1.5 0.3 0.6 7.9 0.8 147.6 0.9 2.3 1.2 2.4 6.1 6.9 1.0 1.9 3.2 3.1 0.7 0.0 1.2 0.0 1.7 0.6 257.4 11.3 1.6 0.0 0.3 0.3 34.2 3.4 0.3 21.4 0.0 0.7 17.1 1.0 7.5 3.7 0.6 0.5 1.2 7.5 0.8 1.1 6.0 3.3 44.3 0.0 1.9 4.6 91.8 3.3 0.6 0.6 0.4 0.7 0.7 0.8 0.5 LNX2 "MGC46315, PDZRN1" ENSG00000139517 "Ligand of numb-protein X 2" Q8N448 13 27545913-27620529 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040698 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Plasma membrane, Cytosol" "HPA040698: AB_10673138" "unprognostic (4.97e-2)" "unprognostic (1.97e-2)" "unprognostic (3.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-2)" "unprognostic (1.12e-1)" "unprognostic (8.38e-2)" "unprognostic (1.16e-1)" "unprognostic (9.27e-3)" "unprognostic (4.21e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.09e-13)" "unprognostic (4.18e-3)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.84e-2)" 3.2 6.7 2.0 3.7 2.3 3.8 6.9 5.1 3.0 4.0 6.5 10.7 14.2 3.0 4.8 10.6 4.6 7.9 8.7 2.4 2.8 7.9 20.5 11.5 4.0 1.7 1.8 4.3 19.6 7.1 3.2 3.7 1.7 6.4 10.5 8.0 9.4 4.8 5.9 6.6 13.4 3.8 1.9 3.1 9.9 12.3 2.4 7.8 9.9 5.9 5.1 6.2 6.7 1.9 6.4 3.5 6.5 7.2 6.7 3.1 6.8 5.6 4.9 5.4 4.9 12.7 12.5 9.6 4.7 4.9 9.8 12.0 11.8 15.0 7.0 6.0 4.9 12.3 7.2 9.3 10.5 6.6 7.6 2.6 22.8 3.8 14.7 15.4 9.9 9.9 3.8 3.6 7.9 7.9 10.0 4.4 7.2 29.0 3.9 9.2 12.7 5.0 11.9 11.1 16.7 3.5 7.6 15.4 10.1 8.0 10.7 5.2 12.6 3.1 4.3 3.1 4.6 3.5 6.3 9.9 2.0 6.3 4.4 2.0 0.3 0.9 0.5 0.1 0.7 0.5 0.6 0.7 0.3 0.5 0.6 0.6 0.3 1.1 0.2 0.1 1.0 0.2 2.0 2.3 5.1 3.0 2.4 2.8 1.7 1.8 1.7 1.9 2.4 1.9 4.5 32.1 27.6 9.8 5.6 25.4 27.7 15.8 23.9 8.9 13.3 7.6 11.4 25.8 11.4 20.2 2.1 1.5 5.5 27.8 3.9 10.2 16.4 11.0 2.7 7.2 10.2 18.9 23.2 14.2 8.1 3.2 11.7 14.7 1.3 10.8 9.3 59.2 2.3 5.0 8.0 17.0 8.2 5.0 7.7 7.3 2.8 2.8 10.6 21.5 2.3 4.4 5.2 3.0 6.7 11.0 23.5 3.4 5.4 16.8 17.8 7.8 15.9 16.3 0.0 3.1 3.5 15.6 17.5 14.8 22.0 3.0 5.5 11.1 11.9 20.9 LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Centrosome "HPA023584: AB_1853233, HPA024814: AB_1853235" "unprognostic (2.59e-1)" "unprognostic (2.17e-3)" "unprognostic (1.35e-2)" "unprognostic (3.56e-1)" "unprognostic (9.09e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (5.78e-2)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-1)" "unprognostic (5.46e-3)" "unprognostic (8.97e-2)" "unprognostic (8.90e-2)" "unprognostic (3.08e-3)" "unprognostic (1.15e-1)" 16.2 5.8 2.8 4.5 2.7 5.9 10.5 3.4 3.7 11.4 1.3 7.7 2.3 11.3 9.6 13.0 10.5 9.5 4.9 3.0 2.3 6.3 9.9 7.3 7.1 2.2 2.1 15.2 7.5 8.0 3.8 10.1 1.9 10.7 4.3 7.9 8.0 10.6 17.2 28.7 4.5 9.2 2.3 8.4 5.4 15.8 2.6 6.8 8.7 11.3 8.1 7.9 8.3 3.0 1.2 3.0 15.0 4.6 15.6 7.4 10.0 3.8 6.3 4.1 5.7 0.9 3.9 24.0 0.9 6.7 12.9 1.8 12.0 4.7 4.6 3.7 6.8 7.9 0.5 6.2 14.4 2.1 3.0 7.0 8.2 2.6 8.9 3.8 6.4 9.7 1.1 56.6 2.7 4.2 10.4 7.0 15.5 4.8 0.9 5.8 10.2 4.3 3.5 10.2 31.2 3.6 2.2 5.1 29.8 10.7 1.0 10.4 2.9 2.2 3.7 8.9 3.0 4.3 20.7 12.4 12.0 7.2 7.0 0.0 0.1 0.6 0.1 0.5 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 2.8 2.7 3.4 3.7 3.0 2.3 2.2 2.1 1.9 2.3 2.6 3.0 18.9 9.6 16.3 23.2 25.2 60.8 32.8 7.8 52.3 25.1 15.1 10.3 9.7 10.0 13.1 11.0 16.7 3.6 6.3 4.3 7.9 5.3 57.4 12.1 27.9 15.1 2.4 4.6 67.0 4.0 8.2 24.2 5.6 28.3 6.3 27.8 6.1 14.7 5.6 8.4 43.6 6.4 4.1 9.5 27.6 53.5 29.2 17.2 44.4 21.5 3.6 8.3 0.0 42.7 14.9 4.3 6.4 19.9 16.3 26.4 3.8 6.0 8.7 13.0 19.7 36.7 32.7 8.2 19.7 26.4 73.6 7.3 9.7 3.4 5.8 30.1 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 LPXN LDPL ENSG00000110031 Leupaxin O60711 11 58526871-58578220 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 118.5" "Cell type enhanced" "Detected in many" "B-cells: 75.9;dendritic cells: 80.7;Langerhans cells: 154.6;Macrophages: 81.7;Plasma cells: 82.2;T-cells: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 200.7;HMC-1: 329.3;Karpas-707: 285.0;U-2197: 199.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043741, CAB046478, HPA061441" Enhanced Supported "Nuclear speckles,Focal adhesion sites,Cytosol" No No "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Focal adhesion sites" "Nuclear speckles, Cytosol" "CAB046478: AB_10603113, HPA043741: AB_2678647, HPA061441: AB_2684518" "unprognostic (1.61e-3)" "unprognostic (6.91e-2)" "unprognostic (6.54e-2)" "prognostic favorable (8.81e-4)" "unprognostic (5.16e-2)" "unprognostic (2.07e-3)" "unprognostic (2.16e-2)" "unprognostic (8.87e-3)" "unprognostic (5.18e-2)" "unprognostic (3.96e-2)" "unprognostic (2.39e-2)" "unprognostic (3.05e-1)" "unprognostic (3.60e-3)" "unprognostic (1.91e-1)" "unprognostic (5.25e-2)" "unprognostic (2.55e-1)" "unprognostic (2.41e-3)" 10.4 8.3 7.5 48.3 8.2 10.2 10.2 7.8 11.8 7.9 4.5 14.5 10.9 7.4 11.9 5.2 7.6 15.1 5.3 7.1 7.8 10.6 14.0 33.5 87.1 9.1 8.8 9.5 8.6 6.5 7.2 5.2 10.2 9.4 19.6 7.0 11.0 7.1 3.8 5.9 26.2 9.7 8.6 44.1 13.0 10.2 10.0 103.3 10.2 5.1 118.5 32.4 6.0 10.9 1.7 2.1 2.0 3.9 7.4 9.3 1.4 50.5 200.7 12.4 22.0 0.4 5.1 149.8 2.0 61.9 9.2 2.0 1.7 137.7 51.4 65.4 0.9 6.8 1.3 1.0 12.8 41.1 329.3 7.2 3.2 170.8 22.0 12.0 80.9 90.0 1.9 285.0 101.5 1.1 144.8 51.6 1.6 2.3 45.8 2.1 2.5 129.2 8.3 71.2 1.0 1.6 2.2 3.2 20.1 2.8 2.7 11.7 79.8 30.8 9.5 199.5 45.9 18.4 18.9 146.5 71.6 36.8 71.6 6.3 74.3 12.2 101.3 41.8 148.9 71.9 102.9 117.6 137.5 46.2 79.6 95.9 14.1 79.2 22.2 124.4 152.1 98.8 7.5 8.2 7.8 11.8 7.1 7.8 9.1 8.8 10.2 8.6 10.0 10.9 4.1 0.0 6.7 22.9 75.9 9.7 6.6 7.2 3.4 4.1 4.0 4.7 2.3 4.3 2.8 0.0 4.2 2.8 80.7 4.2 3.9 2.5 23.0 2.8 1.9 5.9 6.1 13.3 18.2 5.6 1.3 6.6 13.3 2.3 51.5 5.4 2.5 7.6 44.0 1.7 19.8 3.1 6.1 63.7 154.6 8.7 1.8 81.7 19.6 30.0 52.9 2.8 49.4 11.6 27.3 4.1 5.2 3.8 82.2 3.6 6.9 5.7 4.3 4.4 6.6 3.6 3.8 9.2 4.2 2.6 9.7 2.5 90.3 2.9 5.2 27.6 LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 89.2;Inhibitory neurons: 117.6;Microglial cells: 183.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 37.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" Nucleoli "HPA021536: AB_1853258" "unprognostic (7.13e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (3.59e-2)" "unprognostic (8.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (2.16e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.04e-4)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" 15.1 5.0 4.7 10.7 4.7 8.9 14.6 37.1 6.2 15.9 4.2 15.2 7.9 16.3 7.7 10.0 11.8 12.6 8.4 5.7 6.1 14.9 12.2 13.8 16.3 6.5 7.0 10.1 5.6 5.4 5.8 18.2 7.8 10.8 10.0 10.3 10.0 12.0 3.9 17.9 11.6 17.6 7.9 14.6 13.0 4.6 6.8 18.5 6.5 7.5 15.7 13.5 9.7 7.5 7.4 10.4 9.2 9.6 6.6 12.5 23.6 12.4 16.1 15.0 14.2 23.5 12.3 23.4 3.4 11.7 9.8 10.4 7.1 12.5 21.6 24.2 6.6 21.0 4.3 11.1 8.2 13.8 34.5 7.9 9.7 13.9 16.8 12.3 13.1 15.6 4.2 6.9 11.2 14.2 14.8 17.3 5.2 46.3 5.5 8.0 10.0 6.3 28.1 7.5 14.5 14.6 7.0 6.8 18.8 16.2 5.3 18.3 12.5 8.8 6.0 11.0 11.9 1.3 3.7 10.6 10.3 11.9 10.8 0.6 0.9 0.9 1.5 0.7 0.8 2.2 1.1 1.0 0.8 2.7 0.8 0.9 0.3 2.5 0.5 1.0 0.8 0.9 4.7 4.7 37.1 6.2 5.7 6.1 6.5 7.0 7.8 7.9 6.8 7.5 61.5 6.4 6.1 24.8 26.7 37.5 10.5 6.2 27.3 8.3 12.0 11.8 7.2 17.2 6.5 22.0 22.9 13.4 8.4 6.8 9.8 8.3 1.6 5.4 6.5 32.5 1.8 9.9 89.2 4.2 12.7 14.3 18.8 13.7 27.9 2.8 17.5 9.3 13.4 3.3 117.6 10.6 8.2 16.9 30.7 2.1 13.1 12.3 30.2 183.6 8.4 5.5 8.2 64.8 9.7 13.5 5.5 17.0 12.4 12.9 8.0 8.4 2.6 8.5 13.1 15.6 18.6 1.7 4.1 15.9 33.2 9.7 14.7 15.3 7.8 9.2 LRCH4 "LRN, LRRN1" ENSG00000077454 "Leucine rich repeats and calponin homology domain containing 4" O75427 7 100574011-100586129 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 205.8;Syncytiotrophoblasts: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 79.6;NB-4: 174.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037667, HPA037668" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Focal adhesion sites, Cytosol" "HPA037667: AB_10671882, HPA037668: AB_10672910" "unprognostic (2.41e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.32e-3)" "unprognostic (2.76e-2)" "unprognostic (3.96e-3)" "unprognostic (8.98e-3)" "unprognostic (3.72e-2)" "unprognostic (2.52e-1)" "unprognostic (5.51e-2)" "unprognostic (2.63e-3)" "unprognostic (7.81e-2)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (7.96e-2)" "unprognostic (1.26e-2)" 29.0 37.5 15.8 25.3 18.3 49.2 26.8 16.8 26.1 32.5 17.0 32.7 19.1 28.3 5.1 35.8 33.7 8.5 28.0 15.5 17.7 35.5 30.9 52.0 33.6 21.4 17.1 55.3 33.5 12.7 51.2 10.9 20.5 36.1 5.5 21.4 36.3 8.8 41.4 30.3 71.6 5.3 16.0 130.1 31.2 112.3 20.3 27.1 47.8 7.2 14.7 24.3 29.9 23.1 15.2 9.8 8.5 9.2 6.5 4.3 17.3 14.5 7.3 9.0 7.1 16.6 24.7 9.9 17.0 3.6 10.7 15.9 5.5 7.0 3.0 10.5 12.2 9.8 12.0 8.1 18.4 18.0 79.6 8.0 7.5 7.6 5.5 7.6 10.3 27.6 18.5 18.7 6.6 32.2 21.2 174.5 11.5 20.5 11.2 25.6 7.1 13.9 10.3 4.2 12.5 18.6 7.8 25.6 20.2 16.2 13.6 40.5 14.4 12.2 23.6 15.2 9.1 23.3 9.9 9.9 9.1 51.6 22.3 22.5 10.6 14.6 5.8 8.4 5.5 6.1 5.9 6.8 7.0 6.6 7.9 6.9 30.6 1.6 5.9 7.7 6.3 3.7 15.8 18.3 16.8 26.1 15.5 17.7 21.4 17.1 20.5 16.0 20.3 23.1 7.5 9.6 12.7 7.5 29.4 12.0 15.4 13.0 5.7 15.9 14.8 8.4 0.8 27.1 15.1 22.0 41.7 39.4 42.9 27.2 15.6 32.7 205.8 11.9 7.7 9.9 6.1 12.2 7.3 24.7 13.9 9.1 14.8 13.5 19.6 12.7 15.4 13.8 32.8 13.5 7.9 11.8 20.3 65.9 33.6 32.3 24.8 40.5 14.2 3.7 66.1 13.6 46.4 4.5 5.2 28.9 13.1 10.1 15.7 12.8 41.9 6.9 12.1 33.5 19.7 9.8 13.3 58.3 33.9 9.0 11.5 103.3 33.7 12.0 10.0 16.4 LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "retina: 17.6" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 33.3;Muller glia cells: 10.2;Rod photoreceptor cells: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: AB_1853277" "unprognostic (5.41e-2)" "unprognostic (6.82e-2)" "unprognostic (4.20e-2)" "unprognostic (6.50e-2)" "unprognostic (3.42e-1)" "unprognostic (7.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.25e-2)" "unprognostic (3.16e-2)" "unprognostic (4.49e-2)" "unprognostic (6.92e-3)" "unprognostic (3.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" 0.2 0.2 0.4 0.0 0.5 0.1 0.3 0.3 0.6 0.4 0.2 0.2 0.0 0.2 0.3 0.2 0.3 0.0 0.1 0.4 0.2 0.7 0.3 0.2 0.1 0.3 0.3 0.2 0.3 0.0 0.2 0.0 0.4 0.3 0.0 17.6 0.2 0.1 0.3 0.6 0.2 0.0 0.2 0.3 0.2 0.5 0.3 0.1 0.3 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.6 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.5 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.1 0.0 0.0 0.0 33.3 0.0 0.0 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 10.2 0.0 0.5 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.7;Excitatory neurons: 78.7;Inhibitory neurons: 53.7;Oligodendrocyte precursor cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.0" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: AB_1857532" "unprognostic (2.17e-1)" "unprognostic (6.80e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.07e-1)" "unprognostic (2.15e-3)" "unprognostic (4.87e-4)" "unprognostic (2.96e-2)" "unprognostic (3.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (9.89e-2)" "unprognostic (7.56e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" 5.7 4.7 5.1 3.9 8.8 2.2 4.3 4.7 9.4 6.4 3.1 4.8 3.1 16.5 4.0 4.1 5.8 7.5 13.6 13.8 5.3 6.5 1.5 4.6 1.6 1.8 2.3 6.1 4.5 10.0 3.1 5.3 1.1 6.5 4.8 6.1 3.8 5.9 9.3 3.1 3.0 18.5 2.4 3.7 2.8 4.9 3.1 12.9 6.8 17.2 2.3 7.6 3.2 3.9 18.5 10.6 21.1 37.1 23.4 18.4 4.7 51.5 51.3 17.6 24.6 2.4 17.7 0.0 20.2 49.0 21.2 8.1 8.6 22.0 37.7 34.3 8.2 28.7 4.7 0.8 14.4 0.4 22.1 24.8 15.4 29.5 23.7 63.4 9.1 21.9 6.2 0.0 63.9 3.0 26.5 0.6 5.3 1.6 18.2 2.1 20.5 4.0 13.9 0.8 27.0 16.4 16.4 0.7 44.6 15.8 5.0 5.6 25.7 48.1 31.0 15.7 33.6 23.8 20.2 0.2 25.9 0.0 53.9 47.0 0.3 5.8 0.2 0.8 1.4 0.0 1.0 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.5 0.4 0.1 0.4 5.1 8.8 4.7 9.4 13.8 5.3 1.8 2.3 1.1 2.4 3.1 3.9 4.4 16.0 2.2 42.7 0.2 11.5 6.3 12.3 10.8 17.5 3.9 4.3 11.7 7.2 5.2 14.7 6.2 0.2 1.7 2.0 0.0 4.6 4.3 4.4 16.4 5.9 14.4 2.5 78.7 4.5 0.5 12.6 1.5 5.5 8.2 10.9 4.2 0.8 5.3 28.6 53.7 2.5 10.2 7.9 14.3 2.7 8.7 8.2 7.2 9.4 6.1 3.1 1.0 64.3 25.2 5.1 0.3 9.1 0.1 7.7 1.5 3.8 5.3 8.3 6.6 8.2 11.3 8.5 12.0 3.2 10.9 0.3 3.9 4.5 2.3 5.2 LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Cone photoreceptor cells: 41.7;Distal enterocytes: 31.1;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 31.3" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 21.3;SuSa: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" 0.7 1.4 23.3 0.9 30.5 0.0 1.5 19.1 21.3 2.3 0.0 4.8 3.4 1.6 0.9 1.8 1.4 2.0 6.9 24.2 16.0 0.7 0.2 2.9 0.1 46.7 23.0 4.6 2.2 5.6 2.6 2.6 19.8 2.1 3.4 7.9 1.7 2.3 4.4 31.6 4.9 1.5 21.3 3.9 7.8 1.1 30.9 1.5 2.4 7.7 0.3 0.9 1.4 25.6 0.1 9.6 21.3 6.5 13.4 3.7 4.9 1.0 1.9 2.8 3.2 2.8 0.0 0.0 1.4 11.4 3.1 3.9 12.0 7.5 2.2 0.0 10.3 1.0 3.8 6.8 2.8 0.1 1.9 4.5 4.2 4.4 1.1 2.5 2.5 2.6 0.9 0.0 1.6 0.8 0.2 0.3 11.9 0.0 0.9 1.6 7.3 0.0 0.3 2.8 0.1 14.2 1.2 0.0 3.4 16.2 0.3 0.5 0.2 5.7 3.5 6.5 2.1 0.0 0.0 0.4 4.3 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 30.5 19.1 21.3 24.2 16.0 46.7 23.0 19.8 21.3 30.9 25.6 0.2 0.0 1.9 123.1 0.0 8.2 2.7 2.4 10.8 0.5 0.3 1.9 6.2 0.0 1.9 1.8 41.7 2.6 0.0 31.1 1.9 0.0 0.5 1.0 4.7 1.0 0.0 0.0 19.7 0.4 0.4 5.0 3.1 4.4 5.1 1.6 1.8 0.4 0.2 0.0 18.6 2.8 0.0 0.0 0.4 0.0 1.8 0.2 1.8 15.0 0.6 9.3 0.0 137.2 31.3 0.3 3.0 1.2 0.0 1.0 8.0 0.3 1.1 2.7 0.0 12.4 0.9 0.2 0.8 2.3 10.9 1.4 0.2 8.4 3.3 0.8 LRR1 "LRR-1, MGC20689, PPIL5" ENSG00000165501 "Leucine rich repeat protein 1" Q96L50 14 49598761-49614672 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 129.5;Spermatocytes: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA065703, HPA069364" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065703: AB_2685537, HPA069364: AB_2686129" "unprognostic (2.73e-2)" "unprognostic (1.21e-2)" "unprognostic (3.17e-2)" "unprognostic (2.26e-2)" "unprognostic (2.85e-2)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (7.34e-2)" "unprognostic (2.50e-2)" "unprognostic (8.30e-2)" "unprognostic (4.64e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (4.90e-7)" "unprognostic (6.86e-2)" "unprognostic (1.21e-1)" "unprognostic (1.86e-1)" "unprognostic (4.04e-2)" 5.7 5.5 1.6 9.1 1.7 22.6 5.6 1.7 2.1 3.0 1.6 12.2 9.6 3.7 2.4 6.7 3.3 3.6 3.2 1.5 1.6 3.1 6.1 4.2 14.0 1.8 1.7 2.4 4.3 2.9 1.2 4.0 1.8 3.2 10.0 3.2 4.1 3.4 4.0 4.7 10.1 6.1 1.7 7.5 4.6 29.1 1.8 23.2 3.4 4.8 13.3 5.4 3.5 1.9 66.5 39.3 34.2 38.4 15.1 10.6 38.2 35.0 30.8 72.5 68.7 38.4 49.1 60.9 25.1 22.9 23.2 41.7 42.2 29.8 64.1 56.5 31.3 27.4 29.4 24.6 8.5 64.5 34.2 6.9 11.3 33.9 19.4 9.2 35.8 49.2 29.3 45.4 49.2 55.2 87.2 60.1 22.5 31.7 53.0 54.8 56.2 41.4 25.4 27.1 36.9 21.7 33.1 35.3 25.4 12.1 49.9 49.6 13.1 50.6 83.1 24.8 44.4 23.6 35.9 69.0 23.6 47.7 42.9 22.4 14.2 25.4 10.1 22.7 13.5 16.1 13.3 14.8 15.0 12.6 10.8 12.3 8.2 11.1 16.9 17.7 15.7 10.5 1.6 1.7 1.7 2.1 1.5 1.6 1.8 1.7 1.8 1.7 1.8 1.9 6.4 3.2 6.5 2.0 12.1 15.6 5.7 12.0 4.6 3.8 6.5 5.6 3.6 5.7 9.3 3.7 2.1 12.6 9.2 11.8 1.9 16.8 129.5 3.4 5.3 8.9 4.8 48.4 0.9 22.7 34.2 7.8 6.6 2.9 14.5 9.5 6.8 6.6 21.6 1.7 1.1 11.0 12.2 10.4 19.2 41.6 7.5 11.5 10.6 2.8 16.7 8.1 13.4 1.0 2.0 14.1 3.7 3.4 31.3 11.2 8.7 7.5 4.3 5.2 6.6 5.5 8.0 151.7 14.0 8.8 14.9 7.7 10.5 7.5 14.5 7.0 LRRC2 ENSG00000163827 "Leucine rich repeat containing 2" Q9BYS8 3 46515385-46580099 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 45.3;skeletal muscle: 165.0;tongue: 94.1" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 198.4" "Cancer enhanced" "Detected in some" "thyroid cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 7.2;HEL: 4.2;LHCN-M2: 4.1;TIME: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039138, HPA064844" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA039138: AB_10795461, HPA064844: " "unprognostic (1.32e-4)" "unprognostic (3.44e-3)" "unprognostic (2.29e-2)" "unprognostic (3.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.44e-1)" "unprognostic (7.38e-3)" "unprognostic (1.61e-1)" "unprognostic (7.42e-2)" "unprognostic (1.45e-1)" "unprognostic (3.72e-3)" "unprognostic (2.17e-1)" "unprognostic (2.23e-2)" "unprognostic (1.09e-1)" "unprognostic (2.53e-1)" "unprognostic (1.96e-2)" "unprognostic (1.24e-1)" 2.4 0.7 1.5 0.7 3.6 0.8 1.9 1.1 2.8 3.5 0.2 1.9 0.7 4.8 2.4 1.4 2.4 3.0 45.3 2.7 0.1 4.5 5.6 1.2 0.5 0.4 0.4 5.2 1.1 0.9 1.2 0.9 0.3 2.1 1.6 0.3 2.2 0.3 165.0 1.9 0.8 4.0 0.2 2.8 1.8 0.8 0.1 3.2 22.1 94.1 0.7 2.3 2.0 1.4 0.1 0.0 0.1 0.1 0.6 1.4 0.1 0.5 1.0 0.3 0.5 0.0 0.1 0.2 0.1 7.2 0.0 0.1 2.5 0.0 0.9 0.3 0.0 4.2 0.3 0.0 0.1 0.1 0.0 0.1 0.0 2.8 0.0 2.3 0.1 0.5 0.0 0.2 4.1 0.0 0.5 0.1 1.0 0.3 0.1 0.1 0.0 0.2 0.0 0.2 0.3 0.8 0.5 0.1 1.0 0.7 0.1 0.5 3.2 0.1 0.3 1.6 1.1 0.2 0.2 1.9 0.1 0.1 0.9 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.5 0.2 0.1 0.1 0.5 0.1 1.5 3.6 1.1 2.8 2.7 0.1 0.4 0.4 0.3 0.2 0.1 1.4 1.6 9.6 1.1 2.0 0.2 1.9 1.1 0.6 0.6 0.1 0.8 1.3 198.4 7.2 0.0 1.8 0.0 0.1 0.0 0.2 9.8 0.6 2.3 0.3 1.6 4.0 3.0 0.0 12.5 1.0 0.0 11.9 3.1 0.4 10.2 2.5 5.0 10.2 2.0 0.0 11.2 1.8 0.0 0.8 5.7 2.9 0.6 0.6 10.6 3.7 0.0 0.4 0.0 3.5 0.7 1.0 0.4 0.0 3.0 0.6 0.0 0.8 0.7 0.2 0.0 32.7 2.6 0.6 0.7 0.0 2.4 0.1 2.1 7.9 1.9 0.4 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC28 "FLJ34269, FLJ45242, MGC24976" ENSG00000168904 "Leucine rich repeat containing 28" Q86X40 15 99251362-99390729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.1" "Cell type enhanced" "Detected in many" "Early spermatids: 159.2;Excitatory neurons: 127.4;Late spermatids: 406.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039378, HPA040784, HPA066130" Approved Approved "Nucleoplasm,Golgi apparatus,Mitochondria" No No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Golgi apparatus, Mitochondria" "HPA039378: AB_2676476, HPA040784: AB_2677135, HPA066130: AB_2685623" "unprognostic (4.84e-2)" "prognostic favorable (1.41e-4)" "unprognostic (2.82e-3)" "unprognostic (9.86e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (8.02e-2)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.97e-5)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (5.89e-2)" "unprognostic (8.37e-2)" "unprognostic (3.95e-1)" "unprognostic (1.65e-3)" "unprognostic (1.41e-1)" 8.1 7.8 4.4 4.4 5.1 8.6 6.4 4.5 5.8 6.1 4.3 8.0 16.9 5.8 7.4 9.7 4.8 9.1 9.7 5.3 3.9 19.4 47.1 5.3 6.9 3.7 3.5 4.9 19.5 9.4 4.1 6.1 3.5 5.3 9.7 6.8 6.1 6.6 18.3 10.4 16.5 7.9 3.3 4.9 8.2 28.5 3.9 22.6 6.6 18.4 9.4 6.5 6.3 4.4 4.0 9.8 9.5 12.3 13.2 18.7 4.0 4.2 11.9 7.1 8.3 7.4 8.6 8.2 7.6 10.1 8.7 8.8 7.0 13.5 10.3 5.0 10.2 5.5 4.0 7.7 11.7 5.5 8.6 11.1 18.2 6.7 13.4 16.0 22.7 13.0 4.9 8.1 14.9 8.0 15.2 8.9 4.0 31.2 3.7 9.3 8.0 7.6 15.1 12.8 4.3 5.5 10.1 5.4 16.4 14.4 8.4 10.2 8.3 7.0 4.8 5.4 8.4 15.9 24.1 5.1 8.8 5.4 13.3 23.4 9.3 32.0 7.2 7.8 5.8 6.2 6.7 7.7 8.4 5.8 6.2 5.4 5.0 5.1 8.0 6.9 10.4 6.1 4.4 5.1 4.5 5.8 5.3 3.9 3.7 3.5 3.5 3.3 3.9 4.4 13.2 16.0 4.1 29.0 13.5 13.8 14.5 14.5 12.5 19.9 8.9 12.4 13.4 12.8 11.0 11.0 22.9 17.5 11.4 18.6 27.4 12.7 159.2 7.4 8.4 11.9 9.1 12.4 127.4 29.5 22.6 8.5 15.8 6.5 2.5 15.0 12.8 37.0 19.3 21.9 86.8 16.0 20.3 19.8 20.1 406.4 12.8 15.3 14.2 37.5 19.1 14.4 14.4 63.3 63.0 14.8 24.2 8.6 14.7 8.4 72.3 74.1 10.1 19.8 0.0 10.7 11.7 77.1 39.0 15.1 15.8 13.0 11.3 18.0 19.5 15.4 LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 137.9;Respiratory ciliated cells: 129.6;Spermatocytes: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 8.1;HL-60: 8.9;JURKAT: 7.1;NTERA-2: 7.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Cell Junctions,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA035747: AB_10670120" "unprognostic (1.04e-2)" "unprognostic (5.71e-2)" "unprognostic (5.67e-2)" "unprognostic (5.64e-2)" "unprognostic (9.74e-3)" "unprognostic (5.46e-2)" "unprognostic (9.74e-2)" "unprognostic (8.24e-2)" "unprognostic (6.39e-3)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" "unprognostic (1.23e-1)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" 1.5 0.4 1.6 0.6 2.1 1.4 1.1 1.6 2.7 0.9 2.8 0.5 0.2 0.7 0.3 0.2 5.5 0.3 1.1 1.2 2.1 0.7 0.2 1.0 0.8 2.1 2.5 0.8 0.2 0.3 2.8 0.2 2.2 0.6 0.1 5.6 0.3 0.7 0.4 0.5 0.4 0.2 2.1 0.7 0.4 12.8 1.9 0.6 0.9 0.4 0.3 0.4 0.4 1.8 2.3 0.4 0.5 0.0 0.9 3.0 0.0 0.9 1.9 2.4 2.1 0.1 0.0 1.5 0.1 0.6 3.1 0.0 1.8 0.0 0.8 0.4 5.6 8.1 0.2 0.0 0.6 8.9 1.8 0.9 0.4 0.8 0.0 0.1 1.6 7.1 0.2 0.0 0.9 0.0 0.8 1.1 7.7 0.0 2.6 4.0 0.0 0.4 2.1 0.2 4.0 3.1 0.5 0.3 0.0 0.2 0.0 4.2 0.5 0.4 0.0 0.3 0.1 0.1 0.1 1.9 3.5 0.1 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.1 1.6 2.1 1.6 2.7 1.2 2.1 2.1 2.5 2.2 2.1 1.9 1.8 3.9 3.2 2.6 8.5 1.5 0.4 0.9 5.3 0.0 6.9 0.4 0.9 3.2 0.0 12.9 5.5 37.5 0.2 1.6 0.1 1.9 0.5 137.9 33.8 5.8 3.0 4.2 4.2 15.1 0.2 0.3 5.0 0.5 1.0 1.3 1.0 10.4 0.3 2.4 11.8 12.5 0.4 6.1 0.8 1.2 36.3 10.5 1.2 0.0 3.7 3.8 7.4 0.0 9.5 3.6 0.3 0.0 10.5 0.7 0.4 0.0 3.6 129.6 18.8 0.0 3.6 3.7 104.4 9.2 0.1 0.3 0.5 0.9 1.9 0.2 0.4 LRRC45 MGC20806 ENSG00000169683 "Leucine rich repeat containing 45" Q96CN5 17 82023305-82031151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023372, HPA023382, HPA024768" Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Nucleoplasm, Plasma membrane" "HPA023372: AB_1853317, HPA023382: AB_1853318, HPA024768: AB_10602348" "unprognostic (6.69e-2)" "unprognostic (6.10e-2)" "unprognostic (6.86e-2)" "unprognostic (1.38e-2)" "unprognostic (6.92e-2)" "unprognostic (4.41e-3)" "unprognostic (4.70e-3)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (1.78e-3)" "unprognostic (6.17e-3)" "unprognostic (7.46e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (4.79e-2)" "unprognostic (3.58e-1)" 5.0 6.1 2.3 3.8 2.2 7.0 5.8 7.5 5.4 6.1 2.2 8.7 5.7 5.4 0.9 10.3 9.0 1.6 5.0 2.5 1.9 7.5 18.0 6.4 3.2 3.0 2.8 4.5 10.1 2.0 5.9 2.4 3.0 8.4 1.7 0.6 9.6 2.2 2.5 8.7 8.6 1.2 2.1 9.5 10.5 4.0 2.2 3.1 8.9 0.5 1.5 6.1 6.9 2.3 18.6 20.7 6.2 12.7 2.5 3.3 24.0 12.7 5.2 7.5 6.3 18.6 12.4 13.9 11.2 2.5 7.8 21.3 6.0 7.6 1.7 8.5 38.6 8.8 43.1 25.5 2.1 10.4 21.2 3.3 3.1 4.5 1.2 3.1 11.1 13.0 6.3 6.0 2.0 31.6 23.5 34.5 6.4 15.0 27.4 19.0 12.2 7.8 4.8 16.9 19.1 18.6 5.8 29.9 11.2 3.0 24.4 12.0 6.5 13.1 16.3 20.8 21.9 11.5 3.1 2.1 7.0 8.9 13.9 2.3 1.2 1.5 1.4 0.9 1.4 0.6 1.6 1.6 0.8 0.7 0.8 1.1 0.0 1.1 0.4 1.3 1.4 1.4 2.3 2.2 7.5 5.4 2.5 1.9 3.0 2.8 3.0 2.1 2.2 2.3 3.9 6.4 2.2 4.2 4.1 4.5 5.0 2.9 1.8 5.2 8.5 8.6 2.7 14.3 7.0 3.7 0.0 12.7 7.8 18.1 5.9 7.3 1.5 19.0 3.4 3.7 4.8 10.3 2.5 4.7 27.9 4.8 13.3 5.0 4.5 13.3 7.1 12.6 8.7 5.0 2.9 12.2 4.1 6.3 3.2 4.4 7.2 4.2 8.8 0.0 4.3 5.6 7.2 1.0 1.8 5.8 9.4 6.4 8.5 2.4 10.9 10.2 24.4 4.1 0.0 2.8 5.2 2.3 11.9 6.3 2.4 3.0 7.0 4.9 18.4 3.7 LRRC7 "densin-180, KIAA1365" ENSG00000033122 "Leucine rich repeat containing 7" 1 69567922-70151945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 20.2" "Group enriched" "Detected in many" 20 "Excitatory neurons: 1132.4;Inhibitory neurons: 996.9;Oligodendrocyte precursor cells: 1038.0;Oligodendrocytes: 408.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 6.9;basal ganglia: 17.0;cerebral cortex: 20.2;hippocampal formation: 17.7;thalamus: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 12.6;HEL: 44.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005625 Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA005625: AB_1853340" "unprognostic (2.81e-2)" "unprognostic (1.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.98e-3)" "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (4.84e-3)" "unprognostic (2.92e-2)" "unprognostic (1.06e-3)" "unprognostic (1.46e-1)" "unprognostic (5.64e-6)" "unprognostic (1.31e-2)" "unprognostic (1.74e-2)" "unprognostic (5.13e-3)" "unprognostic (2.08e-3)" 0.1 0.2 6.9 0.1 17.0 0.2 0.0 0.0 20.2 0.2 0.0 0.4 0.1 0.2 0.1 0.2 0.0 1.0 1.4 17.7 1.7 0.8 0.2 0.0 0.1 0.0 2.2 0.1 0.8 0.1 0.0 0.2 0.0 0.3 0.6 1.5 0.0 0.1 1.0 0.2 0.2 0.2 0.0 0.0 0.2 1.6 11.4 0.0 2.2 0.0 0.0 0.1 0.1 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 4.4 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.6 44.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 4.7 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 6.9 17.0 0.0 20.2 17.7 1.7 0.0 2.2 0.0 0.0 11.4 2.9 0.8 0.0 0.0 41.4 2.5 0.8 0.6 0.4 1.8 44.4 0.3 0.3 6.2 2.8 0.2 0.0 2.1 0.4 2.4 0.0 0.0 0.0 29.4 0.5 1.4 1.2 0.0 3.2 1132.4 0.0 0.5 1.8 0.0 1.4 0.0 0.6 2.9 6.5 0.3 6.7 996.9 0.0 0.0 2.8 3.6 6.3 0.6 0.5 5.4 17.8 1.7 1.0 2.1 1038.0 408.2 0.0 0.0 3.0 1.3 0.9 0.0 1.6 0.1 8.3 0.0 1.4 1.5 9.2 3.0 0.5 1.3 0.1 2.3 0.1 0.0 0.1 LRRC75A "C17orf76, FAM211A, FLJ35696" ENSG00000181350 "Leucine rich repeat containing 75A" Q8NAA5 17 16441577-16492193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 62.1;SK-MEL-30: 21.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028528, HPA065840" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028528: AB_10600755, HPA065840: " "unprognostic (1.09e-1)" "unprognostic (5.60e-2)" "unprognostic (5.79e-2)" "unprognostic (3.85e-5)" "unprognostic (3.93e-2)" "unprognostic (3.23e-2)" "unprognostic (3.44e-1)" "unprognostic (7.66e-3)" "unprognostic (7.74e-2)" "unprognostic (2.84e-1)" "prognostic favorable (7.46e-5)" "unprognostic (8.36e-2)" "unprognostic (4.28e-3)" "unprognostic (8.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-3)" "unprognostic (2.06e-1)" 5.5 21.5 6.8 6.4 5.0 16.1 0.5 1.8 7.7 1.3 0.1 20.2 47.4 4.0 0.2 2.1 1.3 3.1 2.4 6.8 6.5 2.0 0.6 4.6 5.6 4.1 6.7 4.4 7.0 4.7 3.1 3.4 5.1 1.9 9.0 2.3 1.3 1.1 2.9 2.2 44.0 2.3 3.4 21.5 7.4 10.6 5.1 0.5 4.9 0.6 1.6 1.5 0.5 5.3 8.9 6.3 7.6 6.0 0.2 0.2 1.3 2.4 0.4 1.8 1.5 7.9 2.6 0.6 6.6 0.2 3.7 3.7 0.2 0.0 0.0 3.4 6.5 62.1 3.9 0.0 0.3 1.5 7.3 0.0 0.0 0.4 0.0 3.2 2.3 9.4 3.9 1.7 0.1 12.8 15.3 6.7 1.7 20.3 0.7 5.8 5.5 0.8 0.4 1.8 16.6 4.6 0.6 1.8 21.7 3.3 1.4 1.4 0.0 2.2 10.5 6.7 11.9 12.2 2.6 2.0 0.8 5.1 7.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.7 0.3 0.4 1.0 0.0 0.0 0.4 6.8 5.0 1.8 7.7 6.8 6.5 4.1 6.7 5.1 3.4 5.1 5.3 40.5 41.7 69.7 10.7 21.6 0.0 9.6 0.0 2.2 9.1 24.9 13.3 0.7 14.3 19.8 1.8 6.2 16.1 24.8 52.5 19.6 3.9 7.1 30.0 61.0 14.7 24.7 9.7 5.3 7.1 20.4 30.5 2.0 58.7 29.7 25.0 11.0 10.0 12.0 3.3 3.6 52.2 0.0 13.9 0.0 8.0 16.4 22.9 0.0 1.0 7.7 21.3 2.1 4.0 4.2 6.2 36.0 11.3 12.0 8.7 65.4 19.4 8.7 18.2 13.1 22.9 19.4 8.0 6.5 1.1 0.0 16.7 18.6 66.3 66.0 7.5 LRRC9 FLJ46156 ENSG00000131951 "Leucine rich repeat containing 9" Q6ZRR7 14 59919713-60063559 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 5.4;choroid plexus: 12.4;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 112.6;Excitatory neurons: 28.0;Inhibitory neurons: 18.0;Late spermatids: 75.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040965, HPA041381, HPA077675" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "Nucleoplasm, Nuclear bodies" "HPA040965: AB_2677225, HPA041381: AB_2677444, HPA077675: " "unprognostic (1.01e-2)" "unprognostic (2.00e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-3)" "unprognostic (2.80e-1)" "unprognostic (2.95e-3)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (1.91e-2)" "unprognostic (4.82e-2)" "unprognostic (3.45e-3)" "unprognostic (6.06e-2)" "unprognostic (2.62e-3)" "unprognostic (8.54e-3)" "unprognostic (8.30e-2)" "unprognostic (1.67e-2)" "unprognostic (2.29e-2)" 0.3 0.1 0.9 0.0 1.6 0.1 0.0 1.0 0.6 0.0 12.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 5.2 5.4 0.0 0.0 0.7 0.5 0.0 3.7 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 8.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.0 0.6 1.0 1.7 5.2 5.4 3.7 4.3 1.9 5.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.6 1.5 0.1 0.1 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.7 18.0 0.0 0.0 0.0 0.0 75.8 0.9 0.1 0.0 1.9 0.0 0.8 0.0 5.5 2.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 2.9 0.2 0.0 0.0 0.0 10.3 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 8.3;lung: 9.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 3.9;Collecting duct cells: 1.8;Ductal cells: 3.8;Proximal tubular cells: 2.4" "Group enriched" "Detected in many" 7 "lung cancer: 4.6;ovarian cancer: 3.6;renal cancer: 11.7" "Region enhanced" "Detected in some" "basal ganglia: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "RPTEC TERT1: 79.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 73000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: AB_2686770" "unprognostic (6.16e-2)" "unprognostic (1.69e-3)" "unprognostic (2.40e-3)" "unprognostic (9.04e-3)" "unprognostic (5.95e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-1)" "unprognostic (8.94e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-2)" "unprognostic (2.79e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-3)" "unprognostic (2.33e-2)" "unprognostic (6.88e-2)" "unprognostic (2.31e-1)" "unprognostic (9.84e-3)" 8.3 0.0 0.3 0.0 2.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.6 2.2 0.1 9.7 0.0 0.2 0.2 0.4 1.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.3 1.4 0.0 3.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 79.6 0.0 0.3 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.1 0.0 1.0 0.2 0.6 0.2 0.2 0.0 0.1 0.7 0.0 0.0 9.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LRWD1 "CENP-33, DKFZp434K1815, ORCA" ENSG00000161036 "Leucine rich repeats and WD repeat domain containing 1" Q9UFC0 7 102464956-102473168 "Predicted intracellular proteins" "DNA replication" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "testis: 275.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1002.6;Spermatocytes: 677.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021320 Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Vesicles" "HPA021320: AB_1853372" "unprognostic (1.50e-1)" "unprognostic (1.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.66e-3)" "unprognostic (1.60e-2)" "unprognostic (2.08e-3)" "unprognostic (1.72e-3)" "unprognostic (4.97e-2)" "unprognostic (3.34e-1)" "unprognostic (3.04e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.46e-2)" "unprognostic (4.14e-2)" "unprognostic (7.82e-2)" "unprognostic (9.20e-2)" 8.2 16.8 10.7 6.8 10.7 14.9 7.9 11.4 13.1 10.4 10.7 8.9 5.3 10.0 2.3 7.7 13.8 3.9 9.7 13.0 11.5 11.4 15.0 10.1 8.1 12.1 14.4 9.4 9.3 8.7 17.6 3.1 12.2 8.6 2.3 3.4 7.6 6.1 13.2 6.7 17.1 4.2 10.8 24.3 9.0 275.2 12.1 8.7 10.0 5.3 7.3 8.9 7.3 10.2 18.6 24.6 13.0 36.8 9.4 7.2 21.0 19.6 11.9 30.5 20.9 23.7 10.3 44.8 27.5 13.9 36.3 19.2 18.7 16.4 9.0 16.6 39.2 10.0 11.1 14.8 12.7 17.6 17.4 6.7 9.9 35.4 7.5 10.2 16.2 33.9 44.5 13.3 16.8 54.3 53.4 42.1 28.7 22.0 37.8 28.2 12.2 48.5 9.2 11.3 17.7 50.7 21.0 20.1 19.3 14.6 11.2 14.4 11.1 17.3 37.7 54.8 30.8 50.5 94.3 43.6 19.3 17.1 31.4 10.6 2.6 9.9 9.7 4.0 9.0 10.0 8.4 8.4 2.7 11.8 5.2 6.9 5.5 10.5 3.8 9.7 9.3 6.0 10.7 10.7 11.4 13.1 13.0 11.5 12.1 14.4 12.2 10.8 12.1 10.2 9.1 0.0 1.1 5.5 10.6 10.5 6.4 16.5 3.4 11.7 5.5 5.0 0.8 2.8 12.8 12.9 2.1 9.2 10.8 8.6 7.9 12.3 1002.6 54.4 7.3 6.5 7.8 13.7 4.7 10.5 12.4 7.0 10.7 13.7 0.0 14.8 5.7 7.2 8.8 5.0 5.0 9.8 18.3 3.4 4.0 172.3 19.0 5.0 5.4 2.8 7.2 7.9 10.3 4.5 2.8 12.4 11.2 15.8 20.2 3.9 8.6 15.9 65.3 11.4 0.0 5.4 13.6 677.0 38.3 4.5 9.8 6.2 9.3 22.2 7.5 3.4 LSG1 FLJ11301 ENSG00000041802 "Large 60S subunit nuclear export GTPase 1" Q9H089 3 194640791-194672463 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037704, HPA037705" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 60: Granulocytes - Receptor signaling" "Nuclear bodies, Cytosol" Nucleoplasm "HPA037704: AB_10672912, HPA037705: AB_2675621" "unprognostic (5.72e-3)" "unprognostic (9.38e-3)" "unprognostic (2.63e-1)" "unprognostic (1.23e-2)" "unprognostic (3.74e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (3.21e-7)" "unprognostic (4.63e-2)" "unprognostic (1.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.60e-2)" "unprognostic (4.86e-3)" "unprognostic (1.42e-1)" "unprognostic (3.00e-2)" "unprognostic (2.70e-1)" "unprognostic (6.77e-2)" "unprognostic (2.07e-1)" 14.9 12.8 13.2 15.8 13.8 28.1 15.8 13.9 15.9 12.8 14.0 15.1 17.2 15.2 19.8 15.9 14.5 12.6 14.0 13.1 14.5 16.6 21.7 12.8 18.7 14.7 16.4 14.2 15.5 16.8 11.1 17.2 15.8 14.6 18.1 14.0 13.8 13.9 23.0 19.3 14.9 14.5 14.0 15.4 13.6 14.4 14.4 17.2 15.5 18.9 21.3 18.2 14.3 15.4 55.6 36.0 21.2 35.3 32.3 17.8 43.1 31.0 30.1 42.9 37.6 47.9 25.1 43.1 93.5 29.4 75.5 39.5 68.2 35.0 52.1 56.3 32.5 46.8 38.4 27.6 22.9 51.1 42.4 17.3 31.5 44.4 41.7 16.0 47.1 29.4 39.5 46.2 36.0 76.6 46.3 30.8 57.7 73.5 65.6 56.2 35.0 49.3 23.7 46.9 40.5 27.9 39.9 38.2 40.0 39.7 90.3 32.9 36.5 32.4 37.3 46.2 66.6 50.6 71.1 97.7 26.2 64.7 52.4 3.5 10.1 13.6 15.3 13.2 17.1 16.6 12.5 13.9 17.2 14.3 14.4 12.9 1.3 21.0 8.9 9.0 15.4 10.6 13.2 13.8 13.9 15.9 13.1 14.5 14.7 16.4 15.8 14.0 14.4 15.4 25.0 19.2 29.6 10.4 22.5 16.2 13.4 8.9 25.0 18.3 12.1 11.9 17.2 18.6 27.9 9.2 12.5 25.1 21.2 14.0 5.9 23.3 12.0 22.1 24.5 23.7 7.8 16.2 10.5 22.4 19.4 17.7 21.9 24.0 53.7 21.9 11.7 14.0 13.0 15.2 8.3 14.2 12.2 4.4 10.2 8.9 15.5 15.5 12.4 8.4 14.0 18.2 12.3 12.5 12.2 19.7 8.0 14.7 23.8 11.5 10.8 9.7 34.3 18.6 19.7 22.1 14.6 26.4 35.7 30.5 16.1 28.5 24.0 23.2 17.6 9.0 LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "granulocytes: 327.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 20.2;eosinophil: 63.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 63.1" "Cell line enriched" "Detected in some" 11 "HMC-1: 102.0" "Low region specificity" "Detected in many" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" 8.9 6.9 1.1 0.5 0.8 2.3 5.5 1.5 1.3 4.2 0.7 3.3 0.7 5.7 0.0 3.1 11.8 0.3 12.4 1.0 1.4 7.1 1.9 7.7 0.2 2.1 1.5 5.7 2.0 0.2 3.5 0.4 1.4 4.8 0.2 0.0 4.3 0.8 1.0 3.1 3.2 0.4 2.9 6.1 3.0 1.5 2.6 0.0 5.9 0.0 0.1 4.8 4.0 4.7 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.9 8.9 0.2 0.4 0.3 0.6 102.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 6.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.2 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.1 20.2 0.5 63.1 0.8 0.6 3.0 0.3 2.1 1.5 8.6 0.2 0.4 1.0 0.3 4.7 0.0 0.4 0.2 0.6 1.1 0.8 1.5 1.3 1.0 1.4 2.1 1.5 1.4 2.9 2.6 4.7 32.3 0.0 3.2 2.9 2.3 9.9 9.6 11.2 14.8 0.4 26.4 38.6 0.0 14.3 6.2 14.7 0.0 10.4 5.0 0.6 1.9 5.9 0.3 4.0 1.5 49.5 3.0 2.1 0.8 2.4 1.9 8.3 3.1 5.6 327.4 0.5 72.1 0.9 41.5 0.0 0.7 1.7 0.0 20.8 46.3 0.9 16.4 53.9 1.8 28.1 2.0 0.1 2.1 1.0 1.5 1.9 0.5 47.4 10.0 3.7 2.2 54.8 5.8 0.5 0.0 0.8 1.6 0.1 0.7 5.2 7.0 3.0 10.0 1.5 3.1 10.0 LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 30.6" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 1890.0" "Group enriched" "Detected in some" 7 "glioma: 3.5;prostate cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.9;HAP1: 4.4;HeLa: 1.9;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: AB_2676307, HPA046161: AB_2679564" "unprognostic (4.49e-2)" "unprognostic (2.74e-2)" "unprognostic (8.63e-2)" "unprognostic (3.50e-1)" "unprognostic (5.22e-3)" "unprognostic (3.38e-1)" "unprognostic (4.88e-2)" "unprognostic (5.67e-4)" "unprognostic (2.40e-1)" "unprognostic (5.66e-2)" "unprognostic (6.16e-3)" "unprognostic (4.09e-2)" "unprognostic (5.18e-3)" "unprognostic (9.41e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" 0.3 6.5 8.6 0.1 8.5 0.1 0.5 11.8 8.0 0.1 1.1 0.8 0.1 0.2 0.0 0.1 0.0 0.1 0.1 6.3 15.1 0.2 0.9 0.2 0.0 10.8 30.6 0.0 0.0 0.0 0.6 0.0 17.2 2.4 0.6 1.1 0.1 0.1 0.0 0.1 0.2 0.3 17.6 0.1 0.1 0.5 15.3 0.0 0.0 0.6 0.0 0.3 0.1 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.9 4.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 11.8 8.0 6.3 15.1 10.8 30.6 17.2 17.6 15.3 16.5 0.3 0.0 0.0 11.4 0.0 0.6 0.1 0.0 1.8 6.9 0.3 1.7 0.6 0.0 0.0 3.7 0.0 0.0 0.1 1.2 0.0 0.0 33.7 0.6 0.7 0.1 0.0 0.0 149.4 0.0 0.1 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 371.4 1.7 0.0 0.0 0.0 6.4 0.9 0.1 0.0 4.7 0.0 0.3 0.0 1890.0 9.1 0.2 23.9 0.0 0.0 4.5 0.0 0.7 0.0 0.8 0.0 0.4 0.3 0.3 0.6 0.9 0.3 0.1 0.0 2.4 1.5 1.6 LYAR "ZC2HC2, ZLYAR" ENSG00000145220 "Ly1 antibody reactive" Q9NX58 4 4267701-4290154 "Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, rRNA processing, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 102.1" "Cell type enhanced" "Detected in all" "Early spermatids: 223.1;NK-cells: 197.8;Spermatocytes: 718.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035880, HPA035881" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA035880: , HPA035881: AB_10669980" "unprognostic (2.81e-1)" "unprognostic (3.79e-1)" "unprognostic (2.64e-2)" "unprognostic (6.22e-3)" "unprognostic (1.44e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (1.08e-3)" "unprognostic (2.92e-2)" "prognostic favorable (8.82e-4)" "unprognostic (5.05e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.94e-2)" "unprognostic (1.61e-1)" "unprognostic (5.90e-2)" "unprognostic (2.72e-1)" 14.8 8.4 7.8 19.8 8.4 20.4 11.2 8.2 13.0 10.0 7.1 10.8 8.8 9.1 5.7 15.9 10.4 8.2 15.6 8.0 9.0 8.8 10.4 11.8 24.3 9.0 8.6 12.4 9.6 5.3 8.4 11.1 8.9 7.8 10.1 11.1 7.3 6.7 21.2 9.2 9.3 9.0 7.9 18.7 7.9 102.1 8.5 12.8 6.7 11.7 17.8 18.8 10.8 9.3 59.9 30.8 26.7 39.3 22.9 26.0 46.1 53.2 18.1 53.7 37.1 97.1 75.6 158.9 37.5 23.0 86.2 37.0 100.6 55.4 69.8 28.6 74.8 159.2 29.5 109.0 38.7 184.4 41.4 20.5 34.4 61.8 103.9 13.9 47.2 89.1 217.9 51.2 37.8 60.5 63.4 236.6 134.0 62.1 99.2 96.2 48.6 76.4 24.4 40.7 63.4 27.4 29.0 31.0 55.8 34.0 32.3 54.4 44.7 53.3 42.7 70.2 169.1 36.2 59.1 250.4 36.5 154.7 44.2 37.3 26.4 24.4 73.5 26.8 85.5 21.7 48.2 80.3 19.5 15.0 22.1 47.9 7.6 30.3 39.2 14.3 25.4 30.2 7.8 8.4 8.2 13.0 8.0 9.0 9.0 8.6 8.9 7.9 8.5 9.3 29.1 16.0 23.5 6.8 26.9 120.1 59.2 19.9 27.9 10.1 15.7 32.9 20.9 14.3 25.6 1.8 8.4 47.7 128.9 11.5 9.8 24.9 223.1 17.7 29.4 32.3 10.7 46.3 3.6 19.8 55.6 31.9 9.7 12.7 21.5 31.5 14.3 11.2 35.8 15.2 4.2 16.1 4.1 30.4 34.0 113.4 34.2 44.7 21.4 2.8 35.2 14.1 197.8 6.0 9.3 30.0 11.4 26.7 36.1 117.5 3.0 7.4 19.2 30.2 39.5 34.4 27.9 718.6 36.6 36.0 115.8 20.2 135.3 46.8 28.9 64.1 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.2;choroid plexus: 15.4;fallopian tube: 53.5;pituitary gland: 33.7" "Cell type enhanced" "Detected in some" "Ductal cells: 73.8;Exocrine glandular cells: 74.5;monocytes: 62.0;Oligodendrocyte precursor cells: 28.1;Pancreatic endocrine cells: 43.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 41.6;HUVEC TERT2: 32.7;SK-MEL-30: 36.5;U-251 MG: 65.9;WM-115: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Vesicles, Plasma membrane" "HPA068333: " "unprognostic (9.25e-2)" "unprognostic (7.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-2)" "unprognostic (6.40e-3)" "unprognostic (5.60e-2)" "unprognostic (8.36e-3)" "unprognostic (1.05e-2)" "unprognostic (6.70e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" 0.6 0.8 24.8 0.3 27.1 0.4 0.8 19.5 25.5 0.3 15.4 8.1 0.1 0.9 0.1 1.5 53.5 1.2 0.8 24.2 29.2 5.9 1.0 1.0 0.6 29.9 30.0 1.3 5.1 0.3 33.7 0.0 27.7 0.7 0.2 1.6 5.5 0.1 0.3 0.3 1.6 0.6 27.3 0.3 0.9 0.7 31.2 2.2 0.9 0.1 1.0 0.8 0.6 21.5 0.4 8.6 11.6 0.2 0.0 0.0 0.0 1.9 1.5 6.3 1.4 0.6 1.1 0.0 18.3 5.1 3.0 7.2 0.0 0.0 2.9 0.1 1.8 0.0 4.0 0.0 0.0 0.0 0.2 0.0 0.1 41.6 0.0 1.7 32.7 0.0 0.0 0.1 0.0 0.8 0.0 0.0 11.1 0.2 3.3 0.0 0.0 0.0 15.1 0.2 1.1 2.3 1.8 0.2 36.5 26.8 0.1 0.3 1.5 0.7 17.4 5.9 65.9 0.1 0.0 0.1 10.0 0.0 140.5 0.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 27.1 19.5 25.5 24.2 29.2 29.9 30.0 27.7 27.3 31.2 21.5 0.7 0.0 0.0 8.1 0.2 0.1 0.1 0.4 0.0 1.6 2.0 0.9 0.2 2.8 0.2 5.5 0.0 0.0 0.0 0.5 1.9 73.8 5.6 1.4 0.1 0.2 1.8 0.0 0.8 74.5 0.0 2.2 0.0 0.9 0.0 0.1 0.4 0.0 0.1 15.2 4.7 0.0 0.0 0.8 0.7 9.3 4.1 0.1 0.0 0.0 62.0 1.4 0.0 28.1 4.4 43.4 0.0 0.0 0.0 0.1 0.1 4.8 0.3 0.8 0.0 0.2 3.9 2.6 2.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 LYST "CHS, CHS1" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883640 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.3;retina: 27.9" "Cell type enhanced" "Detected in all" "monocytes: 277.4" "Cancer enhanced" "Detected in all" "melanoma: 11.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;monocytes: 6.1" "Cell line enhanced" "Detected in many" "HDLM-2: 30.8;SK-MEL-30: 27.1;THP-1: 99.5;U-937: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: AB_2682129, HPA055725: AB_2682898" "unprognostic (1.56e-2)" "unprognostic (1.54e-1)" "unprognostic (9.92e-2)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.32e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (4.08e-2)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (1.99e-1)" 5.2 2.7 2.0 8.5 2.7 31.3 6.4 10.1 3.3 7.1 9.1 4.5 3.0 4.3 2.7 4.2 3.9 5.1 2.2 2.0 2.5 3.6 5.5 5.5 7.5 2.2 2.6 4.5 2.2 6.2 1.8 4.6 2.5 3.4 4.3 27.9 4.3 3.3 1.7 9.7 3.3 4.4 1.1 10.8 7.7 6.1 3.3 25.7 6.4 3.8 6.5 5.7 5.2 3.4 8.6 1.9 0.9 2.0 12.7 14.4 1.3 3.1 12.5 3.3 3.1 0.0 2.3 1.1 1.2 6.8 7.7 4.1 1.2 1.6 2.9 30.8 2.7 2.8 1.9 0.6 2.3 4.2 3.7 4.8 7.8 4.0 10.0 4.8 2.8 1.3 0.2 1.7 2.6 0.4 5.3 8.7 0.2 1.6 0.9 0.4 1.2 0.0 9.2 9.2 5.4 1.1 3.4 0.2 27.1 1.0 1.2 99.5 5.8 2.4 1.1 2.8 2.8 2.1 0.1 0.2 4.1 38.0 7.0 0.4 2.9 5.7 0.6 3.4 0.8 1.0 0.2 0.7 1.7 1.4 0.2 0.4 12.2 1.7 6.1 0.2 0.2 0.7 2.0 2.7 10.1 3.3 2.0 2.5 2.2 2.6 2.5 1.1 3.3 3.4 66.3 19.2 41.1 71.2 70.9 71.0 89.8 14.6 18.8 67.4 17.6 15.6 11.6 15.7 28.4 11.0 93.8 6.7 77.3 25.0 11.7 6.6 24.6 22.6 23.8 51.2 9.6 21.0 151.5 12.3 5.0 27.0 41.3 22.4 112.5 9.4 26.0 15.4 31.9 52.2 155.9 14.3 28.5 65.6 81.3 17.7 28.0 111.4 120.9 159.3 277.4 25.6 88.6 112.1 81.6 39.6 24.2 21.8 37.3 56.0 12.7 10.9 26.7 162.5 13.1 31.2 22.7 93.3 28.0 18.7 65.1 8.8 71.3 13.6 7.6 98.5 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (9.81e-2)" "unprognostic (3.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-3)" "unprognostic (4.29e-2)" "unprognostic (1.65e-1)" "unprognostic (6.25e-2)" "unprognostic (1.25e-2)" 18.4 15.2 9.0 8.9 9.7 6.0 17.3 8.9 10.1 20.1 7.2 20.1 9.9 23.3 4.4 12.6 18.5 9.4 13.4 9.1 9.1 15.8 12.0 16.0 7.3 10.3 9.5 19.5 12.4 11.5 24.7 9.8 10.8 16.2 6.4 3.4 13.0 8.6 14.7 13.6 15.9 11.3 8.1 18.3 13.9 8.2 8.9 6.5 18.8 8.0 5.7 18.1 15.8 9.3 10.3 8.4 12.2 15.0 27.6 18.9 9.6 20.8 14.6 11.6 15.8 4.9 4.2 11.0 7.6 23.4 10.7 13.7 9.3 17.1 4.7 20.5 21.0 11.8 11.8 7.4 14.6 6.4 14.9 17.5 8.5 14.7 10.6 18.4 22.9 10.0 49.8 18.5 13.4 6.3 11.5 6.0 3.8 12.6 9.1 13.4 17.8 4.4 9.2 13.9 11.9 17.9 11.3 19.5 12.4 7.4 9.1 11.7 20.6 27.0 13.3 12.3 11.5 8.0 7.4 3.2 12.2 6.2 13.5 0.0 0.5 0.0 0.7 0.7 0.4 0.4 0.3 0.8 0.4 0.1 0.4 0.3 0.0 0.3 1.0 0.3 0.1 0.5 9.0 9.7 8.9 10.1 9.1 9.1 10.3 9.5 10.8 8.1 8.9 9.3 12.4 12.8 8.6 20.5 7.9 2.2 1.8 3.7 4.0 9.5 7.5 7.6 11.7 5.7 5.2 9.2 6.2 4.1 11.9 10.7 1.9 7.0 0.9 5.5 12.7 10.1 9.1 2.5 14.2 4.9 4.0 10.9 11.2 8.4 5.7 14.7 12.1 8.5 7.7 3.3 13.2 10.0 6.1 8.8 3.5 1.6 8.7 7.1 7.2 14.0 5.0 5.6 5.2 8.0 17.6 6.1 8.9 9.8 9.2 2.3 7.0 7.6 7.3 9.8 0.0 7.0 11.6 4.5 1.5 5.9 3.7 3.6 7.7 10.1 6.7 1.4 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAD2L1BP "CMT2, dJ261G23.1, KIAA0110" ENSG00000124688 "MAD2L1 binding protein" Q15013 6 43629540-43640941 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028729 Supported "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA028729: AB_2672752" "unprognostic (2.60e-1)" "unprognostic (2.06e-1)" "unprognostic (3.92e-2)" "unprognostic (6.97e-2)" "unprognostic (6.91e-2)" "unprognostic (6.92e-2)" "unprognostic (5.74e-3)" "unprognostic (2.67e-3)" "unprognostic (3.60e-1)" "unprognostic (7.18e-2)" "unprognostic (1.71e-1)" "unprognostic (6.64e-2)" "unprognostic (4.61e-2)" "unprognostic (1.18e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-1)" "unprognostic (3.25e-3)" 13.3 16.2 13.6 14.1 13.8 53.5 17.3 14.1 15.8 14.6 15.4 25.9 23.6 12.4 17.3 17.6 16.7 14.4 25.4 14.3 14.9 17.5 21.9 14.9 21.7 13.8 13.2 13.0 16.7 21.1 12.6 14.0 14.2 14.4 27.7 15.2 22.8 13.5 28.5 13.2 18.8 14.5 13.6 17.4 19.3 20.4 14.3 29.3 15.6 44.6 26.6 21.4 10.6 13.8 53.9 24.4 37.7 42.2 32.1 34.7 22.7 31.7 50.9 68.5 63.8 50.3 21.4 41.6 17.6 37.3 62.2 34.4 59.2 43.9 52.6 38.5 46.0 51.5 26.1 43.8 34.6 30.6 29.9 35.3 53.0 51.1 31.0 34.5 52.2 32.8 67.2 21.8 48.4 50.6 27.4 56.5 23.3 221.1 31.3 31.3 29.3 39.4 48.9 42.5 44.7 45.3 22.8 34.5 152.2 28.6 40.6 80.3 28.7 36.5 30.7 24.4 51.3 27.7 25.8 99.0 33.2 51.3 41.0 105.4 41.4 49.4 46.3 42.8 46.5 52.6 54.7 51.4 52.7 47.9 56.5 51.2 35.2 55.6 41.3 34.9 78.9 43.6 13.6 13.8 14.1 15.8 14.3 14.9 13.8 13.2 14.2 13.6 14.3 13.8 11.6 25.6 12.7 3.3 18.2 14.4 20.5 44.9 17.6 12.8 11.6 9.3 10.8 15.7 32.5 3.7 12.5 21.1 11.1 30.7 27.4 28.0 47.0 13.2 8.6 12.5 17.4 20.6 3.0 21.2 21.5 12.0 14.3 10.8 31.6 7.8 11.4 12.7 17.6 10.1 3.2 17.1 32.6 10.4 8.6 36.5 12.2 19.6 28.4 1.9 17.3 13.9 11.3 3.0 5.0 24.7 29.5 12.0 11.1 11.5 28.2 21.2 21.1 15.1 26.3 8.3 13.4 26.4 18.3 12.6 9.7 6.2 14.8 11.9 23.4 27.2 MAF1 DKFZp586G1123 ENSG00000179632 "MAF1 homolog, negative regulator of RNA polymerase III" Q9H063 8 144104461-144107611 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024821, HPA058548" Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Nucleoli, Vesicles" "HPA024821: AB_2671696, HPA058548: AB_2683751" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.71e-2)" "unprognostic (2.21e-1)" "unprognostic (8.51e-2)" "unprognostic (9.67e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.12e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (9.40e-3)" "unprognostic (9.02e-2)" "unprognostic (2.59e-1)" "unprognostic (2.38e-1)" "unprognostic (3.99e-2)" 96.2 84.4 86.6 61.7 89.7 164.4 92.4 87.3 98.3 97.1 82.5 186.9 62.1 101.9 63.6 81.8 93.3 63.0 193.4 83.5 82.7 89.8 61.1 78.0 78.6 91.2 87.6 110.3 84.6 87.4 71.0 65.1 86.4 103.6 58.3 35.4 77.5 94.6 413.1 69.6 92.2 80.5 85.3 96.5 102.1 76.4 88.7 90.8 78.6 294.7 69.5 130.7 84.1 90.5 119.8 187.1 85.4 86.3 229.0 113.3 68.9 91.8 151.0 140.5 142.1 69.2 129.1 131.0 150.4 154.9 78.1 71.4 117.4 129.9 103.0 115.4 139.5 144.5 127.8 109.6 154.1 62.0 94.4 100.7 150.0 112.8 211.4 156.7 153.6 94.1 112.5 86.9 85.0 281.2 230.9 112.3 64.0 216.3 490.2 90.3 119.7 141.8 89.0 88.8 123.8 102.2 122.0 156.7 152.6 79.5 106.7 93.9 93.0 65.0 146.0 116.1 117.5 102.7 86.0 62.2 107.8 113.7 44.0 50.4 98.0 126.5 72.8 76.1 81.0 110.2 105.0 117.5 107.6 129.9 110.9 105.0 52.9 93.1 78.4 81.0 84.1 111.9 86.6 89.7 87.3 98.3 83.5 82.7 91.2 87.6 86.4 85.3 88.7 90.5 76.8 16.0 15.6 6.8 95.2 92.9 92.4 51.6 53.5 41.4 76.5 77.8 54.2 42.9 24.8 44.1 14.6 106.4 113.9 82.6 105.7 101.1 86.1 30.0 39.3 69.7 93.3 129.0 5.0 107.9 103.6 66.3 28.5 43.6 32.5 77.3 67.5 29.3 97.6 37.0 5.5 89.7 32.6 72.3 85.6 41.0 88.3 84.9 78.2 6.5 138.0 82.0 138.0 7.1 10.7 106.0 97.4 93.3 60.3 170.3 155.0 110.2 12.9 37.6 98.6 65.5 84.8 96.1 43.3 54.0 89.8 144.3 87.6 72.4 88.5 122.4 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAGEA11 "CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511" ENSG00000185247 "MAGE family member A11" P43364 X 149688228-149717268 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "epididymis: 21.0" "Group enriched" "Detected in some" 5 "Spermatocytes: 29.4;Spermatogonia: 30.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2 OS: 23.8" HPA052687 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA052687: AB_2681915" "unprognostic (4.06e-3)" "unprognostic (2.05e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-2)" "unprognostic (9.64e-2)" "unprognostic (1.32e-1)" "unprognostic (6.13e-2)" "unprognostic (1.16e-1)" "unprognostic (6.67e-4)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 23.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 30.9 0.0 0.0 5.9 0.0 0.0 0.0 0.0 MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Granulosa cells: 1684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" 81.6 125.1 102.3 52.8 97.8 31.8 162.6 104.9 112.2 174.5 111.7 106.8 54.3 134.3 101.9 67.4 149.0 94.3 142.2 95.5 121.9 141.0 57.5 85.9 48.0 125.4 118.4 255.9 75.5 148.0 195.3 177.1 128.8 208.8 53.5 74.4 103.3 169.9 88.9 60.5 62.5 140.6 108.5 60.8 77.6 63.1 110.1 68.8 149.2 91.4 46.2 111.7 95.7 108.9 34.0 61.4 373.7 111.0 171.6 229.5 66.8 137.9 243.7 106.4 187.5 62.3 84.4 47.1 361.2 279.0 88.5 45.2 106.5 104.2 76.1 84.5 87.0 100.0 68.6 122.1 145.5 25.4 71.8 310.4 43.0 109.3 55.5 223.6 209.9 55.2 24.5 55.7 207.6 94.0 57.0 41.9 134.7 59.1 72.4 37.4 132.9 68.2 148.5 25.3 56.6 149.5 54.7 62.4 330.6 437.5 263.1 42.9 185.0 90.4 141.3 135.9 39.5 35.7 32.7 34.5 132.0 66.7 477.6 178.5 31.9 132.1 119.1 80.0 91.7 59.2 98.1 112.1 41.1 63.9 97.3 112.0 11.8 108.6 140.8 25.8 108.9 127.4 102.3 97.8 104.9 112.2 95.5 121.9 125.4 118.4 128.8 108.5 110.1 108.9 77.9 44.8 42.8 17.6 37.4 42.4 96.4 198.6 43.3 69.8 123.3 97.8 60.5 44.3 175.4 77.3 29.2 231.5 36.9 11.9 246.5 107.4 3.4 42.4 96.8 116.4 58.3 10.3 12.9 53.7 133.7 151.7 20.9 57.1 102.1 1684.0 79.9 16.2 69.1 138.0 20.3 48.8 173.0 19.5 47.4 17.4 233.3 41.1 158.3 21.5 42.1 175.9 44.3 17.6 20.4 47.9 33.7 320.4 46.7 75.2 25.5 149.3 119.9 66.0 157.8 77.7 236.3 12.8 13.7 15.3 34.9 169.2 51.4 58.6 25.3 76.6 MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 690.5;Microglial cells: 579.9;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 311.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: AB_10671101" "unprognostic (8.11e-2)" "unprognostic (2.51e-1)" "unprognostic (7.08e-2)" "unprognostic (9.07e-2)" "unprognostic (3.57e-3)" "unprognostic (3.32e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (9.11e-2)" "prognostic favorable (1.90e-4)" "unprognostic (9.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (7.19e-2)" 10.9 2.7 5.8 6.3 5.5 3.1 14.2 17.2 3.9 10.6 6.9 6.1 3.0 5.4 1.8 5.5 8.0 7.7 4.4 7.1 10.6 9.9 2.4 9.8 8.7 9.0 9.0 7.9 5.9 5.9 4.0 12.2 7.4 7.4 6.2 6.8 11.0 5.7 2.0 7.9 4.8 6.5 7.0 10.3 4.8 2.3 7.5 13.7 6.5 4.8 7.0 8.8 6.5 6.6 10.7 2.0 17.8 4.7 18.1 20.7 3.8 12.1 17.9 7.8 8.1 1.3 22.1 2.3 27.7 28.1 4.1 9.6 3.6 11.7 10.7 52.8 1.3 1.4 3.7 4.1 10.5 0.1 0.0 30.4 1.1 13.9 8.2 14.3 4.5 0.3 6.1 3.2 14.0 0.9 0.2 2.9 1.9 5.5 3.3 3.7 3.4 12.3 11.6 14.8 0.1 1.6 4.5 1.9 5.0 5.7 1.7 0.5 19.7 13.6 3.2 4.7 7.7 2.2 0.4 3.3 6.5 2.0 25.6 0.1 0.6 0.0 0.8 0.3 1.3 0.9 1.6 2.1 0.6 1.2 3.2 2.2 2.6 2.4 0.4 0.5 0.6 1.2 5.8 5.5 17.2 3.9 7.1 10.6 9.0 9.0 7.4 7.0 7.5 6.6 43.5 16.0 8.6 690.5 35.4 19.5 21.5 12.6 19.9 44.1 28.6 43.1 5.3 18.6 16.6 12.9 91.8 15.4 21.8 31.0 11.7 19.3 1.4 61.6 49.4 24.0 6.7 2.7 81.6 0.4 26.0 41.6 20.9 52.3 1.3 44.0 9.3 0.4 18.6 0.0 36.8 7.6 4.1 19.2 21.2 3.0 8.7 29.3 12.4 579.9 26.0 21.9 16.5 1300.8 311.4 15.0 16.8 8.6 18.1 19.1 9.4 17.1 24.2 25.9 32.9 3.6 51.5 0.6 0.8 19.4 13.5 13.0 38.1 9.0 14.3 19.2 MAP11 "C7orf43, FLJ10925, TRAPPC14" ENSG00000146826 "Microtubule associated protein 11" Q8WVR3 7 100154420-100158723 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 7.0;Extravillous trophoblasts: 7.2;Hofbauer cells: 7.7;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019359, HPA029463, HPA029464" Approved Enhanced "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Plasma membrane, Centriolar satellite" "HPA019359: AB_1848677, HPA029463: AB_10600001, HPA029464: AB_10600205" "unprognostic (1.57e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-3)" "unprognostic (2.59e-1)" "unprognostic (5.23e-2)" "unprognostic (1.06e-1)" "unprognostic (9.36e-3)" "unprognostic (5.68e-3)" "unprognostic (6.97e-3)" "unprognostic (1.25e-1)" "prognostic favorable (6.19e-5)" "unprognostic (2.42e-2)" "unprognostic (1.85e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (6.54e-3)" 7.5 13.3 9.4 16.7 9.6 11.9 8.4 9.6 10.7 9.7 7.4 20.0 14.2 11.8 6.4 15.9 9.5 7.1 7.3 10.4 12.1 16.6 17.2 10.7 20.7 11.5 11.4 6.7 13.8 17.6 17.9 7.3 12.3 12.8 11.5 4.9 15.3 8.4 5.6 25.0 22.5 5.7 7.0 32.2 17.8 30.3 12.0 13.9 15.5 3.8 12.4 9.4 10.9 9.4 7.6 9.7 11.1 18.8 6.8 3.7 12.5 13.9 10.8 9.4 6.8 7.6 8.8 9.6 12.4 10.5 14.6 14.4 5.3 11.0 3.6 18.1 10.6 7.3 13.5 6.7 8.1 9.0 32.1 7.5 7.4 9.1 7.0 6.8 8.3 9.7 15.9 16.9 12.4 23.6 20.7 19.3 12.4 14.0 13.9 12.3 5.1 10.7 8.2 8.6 14.0 14.8 12.5 35.7 7.6 7.3 7.2 10.7 11.5 18.6 15.7 24.7 10.9 24.8 25.4 9.7 10.5 12.3 20.2 0.6 0.3 1.4 0.6 0.6 0.5 0.2 0.8 0.6 0.2 0.6 0.4 0.7 1.9 0.2 0.6 0.2 0.0 0.2 9.4 9.6 9.6 10.7 10.4 12.1 11.5 11.4 12.3 7.0 12.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 MAP1S "BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1" ENSG00000130479 "Microtubule associated protein 1S" Q66K74 19 17719242-17734513 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.9" "Group enriched" "Detected in all" 4 "Early spermatids: 98.1;Late spermatids: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050934, HPA054637" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nucleoli, Cell Junctions" "HPA050934: AB_2681281, HPA054637: AB_2682552" "unprognostic (8.47e-2)" "unprognostic (2.39e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.70e-1)" "unprognostic (8.23e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (2.53e-1)" "unprognostic (6.17e-2)" "unprognostic (4.39e-2)" "prognostic favorable (2.65e-4)" "unprognostic (6.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (8.65e-2)" 20.5 13.9 48.2 8.7 51.9 11.2 19.1 36.8 82.9 18.9 30.1 21.5 7.7 24.8 5.4 11.9 19.2 7.9 18.8 51.4 40.5 15.4 12.4 23.5 9.0 44.7 41.1 21.6 15.6 5.4 22.0 9.7 43.3 17.4 2.4 2.8 19.7 6.5 32.4 12.2 17.7 3.6 39.2 18.3 20.1 74.7 40.6 6.1 16.1 5.4 3.9 21.6 14.6 47.7 30.1 43.2 12.4 16.9 10.4 15.4 34.0 18.3 8.8 10.9 12.3 61.3 16.0 17.3 33.8 11.4 12.8 15.3 10.5 14.5 4.6 21.8 61.1 15.1 36.3 39.2 22.1 16.8 20.9 16.7 8.3 16.7 10.5 7.9 22.6 12.5 24.2 9.5 6.0 39.0 20.8 42.0 28.7 17.1 50.8 33.3 10.2 17.5 14.8 43.4 23.0 26.5 10.7 14.8 18.9 9.0 9.9 17.8 37.3 19.7 18.2 40.7 27.2 18.1 23.3 17.4 23.7 26.7 25.1 18.5 22.6 25.9 15.7 22.2 15.1 15.7 12.3 15.6 25.9 15.5 10.1 13.9 31.4 13.0 17.9 21.2 12.2 19.0 48.2 51.9 36.8 82.9 51.4 40.5 44.7 41.1 43.3 39.2 40.6 47.7 11.1 3.2 7.5 4.2 14.7 10.3 14.0 13.1 13.1 11.1 12.3 8.6 5.5 15.7 12.1 3.7 8.4 21.7 14.0 30.9 3.9 22.2 98.1 12.9 11.5 18.5 20.4 3.8 8.4 17.2 16.9 12.3 19.4 26.9 10.2 12.0 20.7 4.8 26.1 40.4 5.5 16.6 12.2 18.7 25.1 293.2 22.4 20.7 1.8 2.8 17.4 8.1 8.2 4.5 7.1 24.2 15.8 31.6 8.8 14.9 19.0 5.9 6.2 6.3 13.1 7.7 13.0 25.9 21.4 5.4 3.3 33.8 11.3 8.1 18.3 13.7 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: AB_2685331" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favorable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favorable (1.56e-4)" 19.1 17.0 17.9 11.7 17.8 19.4 19.5 16.8 19.0 25.1 10.4 24.4 13.1 26.1 3.7 20.2 20.5 5.9 20.8 14.8 15.2 18.7 24.7 17.1 11.7 17.3 17.3 23.2 21.6 9.6 23.4 9.2 17.1 21.0 4.6 5.6 19.2 7.9 52.4 27.9 20.1 6.2 15.1 24.5 18.8 17.5 17.3 10.9 19.0 16.4 6.1 22.0 22.4 19.9 25.8 14.4 12.2 20.2 9.7 9.3 22.8 16.5 8.0 11.0 11.3 20.9 15.2 30.5 25.9 8.8 10.7 22.9 10.7 12.8 4.3 24.7 53.3 21.4 20.9 15.6 12.4 20.1 26.0 10.8 16.1 8.7 9.8 14.5 10.0 21.9 31.9 38.5 6.5 13.4 28.8 48.6 21.7 13.6 32.0 28.5 13.4 31.0 9.8 21.0 22.4 22.5 11.3 19.4 23.9 7.3 21.0 22.7 15.3 33.2 19.0 23.7 22.7 55.5 27.7 28.8 16.6 29.2 13.6 0.0 0.8 0.6 0.6 0.8 0.4 0.7 0.5 0.6 0.4 1.0 0.5 0.7 1.5 1.0 0.5 0.8 0.2 0.4 17.9 17.8 16.8 19.0 14.8 15.2 17.3 17.3 17.1 15.1 17.3 19.9 15.4 25.6 18.1 11.1 27.0 38.6 37.2 22.7 22.2 52.9 23.5 16.5 14.4 24.3 14.5 20.2 77.2 28.3 27.8 31.1 13.7 22.8 4.8 16.2 20.3 19.5 36.5 23.6 9.9 19.0 31.1 18.5 16.3 24.8 10.8 33.3 21.4 22.2 18.6 57.2 11.0 24.0 32.6 22.2 17.1 11.7 28.9 20.5 32.0 6.5 25.3 23.9 46.4 9.0 15.0 25.7 20.8 12.4 30.4 39.8 38.7 18.4 15.3 65.7 32.9 30.2 22.1 17.7 36.4 22.7 42.6 49.3 30.3 30.3 27.6 33.2 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191426-40215575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.9;Horizontal cells: 23.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 22.8;basal ganglia: 17.5;cerebral cortex: 46.2;hippocampal formation: 37.7;white matter: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favorable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favorable (2.13e-4)" 6.9 8.3 22.8 2.3 17.5 1.9 6.5 0.0 46.2 7.7 0.0 8.6 2.0 7.9 0.3 5.3 6.6 1.8 10.7 37.7 0.1 7.4 5.2 6.7 2.3 3.2 0.6 7.3 6.9 3.3 14.3 1.6 0.0 8.1 0.6 1.4 5.9 2.0 16.8 7.1 6.3 1.8 0.0 8.1 7.1 11.1 2.4 1.8 6.9 4.3 0.9 7.2 6.6 11.6 6.3 7.2 2.2 5.2 2.0 1.2 6.2 4.3 2.0 1.9 1.9 1.7 1.7 5.7 4.4 1.4 4.6 1.9 0.8 2.2 0.2 10.9 6.8 1.4 3.3 1.7 3.8 1.2 3.4 1.1 5.0 2.0 1.4 2.0 1.7 7.6 5.5 9.1 0.5 3.7 4.5 2.2 2.6 2.0 4.7 5.8 2.3 3.4 1.7 3.8 7.4 10.7 4.9 1.7 10.0 1.3 2.4 2.2 2.9 4.9 4.8 7.3 8.3 12.7 7.7 2.6 5.7 2.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 17.5 0.0 46.2 37.7 0.1 3.2 0.6 0.0 0.0 2.4 11.6 5.6 0.0 0.0 6.5 4.2 1.5 1.8 1.1 1.2 14.9 2.9 2.4 2.8 5.7 0.5 7.3 8.4 0.9 3.3 2.4 0.0 2.5 2.8 2.4 3.6 3.6 4.2 5.3 18.9 4.3 0.8 2.6 5.6 3.8 0.0 10.3 3.9 3.2 2.5 23.5 15.9 1.7 0.0 1.6 2.9 7.6 3.1 2.7 1.8 9.4 2.5 5.7 4.1 9.0 12.4 3.7 2.9 4.9 1.5 2.5 1.7 3.1 0.6 7.7 6.6 4.5 4.0 4.1 1.8 1.8 2.7 1.4 4.4 3.2 2.4 2.0 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489094 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favorable (1.11e-4)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 14.7 34.0 18.5 13.0 19.8 15.8 21.0 23.2 25.8 17.0 18.5 24.6 24.3 17.9 56.8 19.7 20.2 18.1 10.4 19.7 20.4 30.9 29.6 17.5 11.7 20.7 21.7 22.2 25.9 34.6 20.7 13.1 21.1 19.7 26.2 36.2 26.2 14.9 4.7 14.0 25.0 17.0 21.2 13.1 23.9 18.8 21.5 11.1 25.7 6.8 15.0 23.2 15.8 23.5 73.9 14.5 27.4 0.7 24.4 29.9 16.1 16.5 11.2 26.2 31.5 27.9 27.0 0.6 55.1 30.4 43.7 41.1 0.8 38.4 46.5 82.1 36.8 0.3 18.9 23.3 26.5 39.2 20.1 27.2 32.8 22.6 28.1 27.1 29.6 0.7 0.9 57.5 23.8 23.0 4.6 18.2 31.5 56.5 33.4 0.6 32.8 40.5 46.9 18.8 44.7 29.8 28.0 41.5 59.9 29.8 62.8 21.5 19.7 21.5 27.8 39.4 36.5 29.3 40.8 24.4 31.4 19.5 36.1 14.0 21.6 9.4 16.6 22.1 25.7 42.8 19.6 21.0 37.4 34.9 27.2 26.6 35.9 20.8 15.9 16.4 8.6 12.4 18.5 19.8 23.2 25.8 19.7 20.4 20.7 21.7 21.1 21.2 21.5 23.5 69.5 54.5 82.7 80.0 41.8 141.6 219.1 196.7 100.7 117.9 144.0 115.1 25.2 144.4 131.6 79.1 91.8 139.5 22.9 96.1 287.6 106.6 134.8 76.5 50.7 65.9 106.4 43.8 170.7 127.5 38.9 49.0 72.4 73.1 29.8 96.6 93.5 99.4 64.9 45.4 184.5 130.9 138.4 53.2 193.0 213.0 43.2 52.7 85.4 28.1 283.9 137.5 22.6 102.1 89.8 137.5 95.1 54.2 40.6 322.2 111.6 283.9 125.7 88.8 46.0 38.5 62.7 119.5 39.1 94.6 145.6 203.4 32.2 50.0 109.3 279.4 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263119-45317029 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 40.6;U-251 MG: 43.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 59: Non-specific - Translation" "Cluster 9: U-2 OS - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_2732436, HPA027270: AB_2732437" "unprognostic (1.05e-2)" "prognostic favorable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 5.9 4.7 2.6 12.5 5.0 5.2 6.4 2.9 2.3 7.1 2.8 15.6 8.1 5.7 1.9 7.8 6.6 5.9 9.9 3.2 2.7 5.1 7.3 8.1 17.7 3.6 4.6 6.0 8.3 4.6 5.9 2.7 3.1 7.0 5.2 2.2 8.1 4.7 28.0 8.5 10.3 5.9 2.5 12.4 7.6 6.9 4.8 13.4 5.8 9.9 16.0 7.2 7.1 2.1 17.1 40.6 3.6 6.5 2.4 7.1 9.4 4.5 3.4 14.9 9.1 5.5 21.0 7.4 24.1 5.3 14.6 11.6 1.5 6.5 7.6 24.3 3.1 1.4 10.1 2.1 7.1 1.1 6.9 10.0 3.6 7.3 3.6 15.6 3.0 3.2 2.7 30.1 8.1 6.1 6.8 1.7 1.8 11.1 5.1 9.5 12.1 17.9 10.5 2.6 3.5 3.0 7.6 3.4 5.0 5.5 2.8 0.4 5.6 6.5 10.2 5.7 43.1 29.1 12.1 4.1 3.9 4.0 9.2 0.0 2.0 0.8 1.6 1.8 1.0 4.2 1.1 1.0 1.4 4.4 1.2 0.9 1.6 2.0 0.6 1.7 2.9 1.6 2.6 5.0 2.9 2.3 3.2 2.7 3.6 4.6 3.1 2.5 4.8 2.1 5.8 3.2 12.8 23.5 15.3 0.0 14.7 0.0 14.8 4.5 5.6 4.8 2.3 18.6 2.5 0.0 4.2 0.9 14.5 13.9 0.0 4.8 4.7 7.0 4.0 6.1 13.1 1.3 8.9 2.7 1.5 6.3 10.2 5.6 1.3 2.1 6.4 9.2 4.9 1.7 15.6 7.8 0.0 9.4 0.0 6.2 4.7 11.3 0.0 26.2 33.4 1.9 5.2 6.6 5.5 3.3 9.6 1.2 8.5 6.2 13.4 3.8 5.1 2.9 0.0 12.9 2.8 4.2 3.0 7.9 0.0 0.0 10.6 2.4 8.5 6.8 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27354067-27366961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 42.9 17.8 17.2 5.5 17.0 0.6 42.6 17.4 20.7 50.2 16.8 25.4 1.8 30.9 4.1 70.0 38.8 4.7 61.8 16.6 17.4 37.3 10.4 54.2 4.7 18.4 17.5 15.6 15.2 5.2 18.0 5.1 17.6 41.3 4.5 1.4 30.3 7.3 15.2 65.7 17.7 12.1 17.3 22.3 23.6 8.3 18.4 2.8 30.3 11.3 7.9 39.8 53.4 16.6 7.2 7.2 6.9 4.4 9.9 12.5 1.4 9.0 5.3 7.2 4.4 2.0 9.4 0.1 8.4 16.4 3.2 10.1 2.0 6.4 3.6 6.5 7.1 0.3 16.0 4.7 2.7 0.5 0.4 10.2 17.6 7.8 2.3 8.8 4.0 0.7 2.0 2.7 10.2 25.1 0.2 9.0 2.2 8.7 8.1 2.3 3.2 1.7 12.9 9.1 2.0 3.0 8.5 7.1 6.3 3.1 4.4 5.0 11.6 13.2 7.2 16.6 5.2 3.5 4.1 0.0 12.1 5.8 4.3 0.9 0.6 3.3 2.8 2.0 3.7 1.5 2.5 3.1 1.3 2.0 1.8 1.6 1.2 0.7 4.5 0.0 3.0 1.2 17.2 17.0 17.4 20.7 16.6 17.4 18.4 17.5 17.6 17.3 18.4 16.6 45.8 19.2 17.8 6.2 3.9 12.5 11.9 8.8 17.1 1.1 8.1 8.9 12.2 5.7 10.3 3.7 0.0 1.2 4.3 8.4 3.9 2.8 0.4 2.3 6.0 27.7 0.0 0.8 1.5 4.4 2.5 10.3 8.6 5.2 2.5 1.2 28.9 0.9 2.8 5.0 1.7 6.1 4.1 8.5 7.1 1.2 16.1 6.4 5.4 5.6 9.3 5.4 8.2 0.0 0.2 12.8 1.9 15.1 3.1 9.5 1.1 1.7 6.2 0.8 6.6 10.8 11.1 13.5 7.7 14.7 14.8 0.1 8.2 0.3 8.8 14.9 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587072 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 11.8 12.5 13.1 12.5 15.1 8.7 14.3 15.6 17.3 14.3 11.7 11.6 9.2 16.6 16.5 10.6 11.0 12.7 16.9 14.7 14.9 11.4 11.6 10.4 16.4 15.3 13.7 15.8 9.7 16.3 13.0 17.4 15.8 14.9 10.9 23.5 12.1 13.3 16.9 13.9 9.8 14.0 15.3 17.6 10.8 9.9 13.8 20.8 14.7 18.4 16.8 14.3 12.2 22.4 16.7 14.4 41.3 35.6 29.5 39.1 29.0 32.7 37.7 28.8 36.1 18.6 15.5 36.9 20.4 35.6 25.6 17.3 26.3 25.5 48.7 19.0 27.7 32.9 19.9 24.9 30.8 36.9 24.4 32.5 30.5 28.2 34.2 33.1 27.4 31.8 67.0 29.3 41.8 20.3 17.2 31.2 34.0 25.7 18.0 29.3 73.9 18.0 24.2 18.4 20.8 29.5 22.9 15.6 24.8 32.2 15.5 64.7 26.5 23.3 14.7 21.6 30.9 25.9 24.7 15.8 35.7 39.7 35.0 18.2 11.5 18.4 12.8 15.9 14.5 13.0 12.3 12.5 14.6 9.9 13.7 13.4 11.5 17.9 17.6 8.9 20.8 13.4 13.1 15.1 15.6 17.3 14.7 14.9 15.3 13.7 15.8 15.3 13.8 22.4 16.1 16.0 26.9 47.0 24.3 36.3 20.8 19.5 21.6 23.3 17.9 12.3 31.0 14.3 16.9 16.5 27.1 31.8 17.8 12.4 7.9 17.6 3.6 10.9 19.8 21.2 12.1 14.1 85.7 20.9 34.6 23.2 16.3 14.8 13.9 25.9 25.7 20.7 24.3 28.6 63.8 13.7 20.3 27.3 24.6 3.2 26.8 21.7 21.4 36.5 35.2 19.6 16.5 50.8 137.2 20.1 9.1 41.0 18.8 30.1 11.1 16.6 21.4 21.5 19.7 28.0 18.5 25.9 24.9 21.3 37.2 48.4 22.7 18.1 15.1 24.8 MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 743.9" "Cell type enhanced" "Detected in all" "Bipolar cells: 392.2;Cardiomyocytes: 921.5;Cone photoreceptor cells: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA 880000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "Plasma membrane" "HPA038149: AB_10672471, HPA038150: AB_10672505" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.95e-2)" "unprognostic (3.36e-1)" "unprognostic (4.57e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.82e-2)" "unprognostic (1.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.30e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.21e-3)" 127.4 55.7 475.5 50.4 483.4 16.1 98.0 433.2 406.8 118.0 215.5 193.2 35.1 111.7 69.7 90.7 94.7 52.9 380.9 351.2 408.7 88.3 66.0 105.0 35.0 567.9 490.6 90.0 71.4 31.4 56.1 64.8 509.2 92.7 47.6 149.0 71.4 88.1 743.9 120.6 80.6 94.5 526.1 64.0 93.9 80.0 552.3 42.1 61.1 491.0 37.8 135.5 115.2 533.2 121.9 95.7 117.1 89.3 168.6 298.5 49.5 222.6 241.2 184.1 204.9 81.3 74.4 102.3 50.7 337.9 172.8 79.2 151.4 201.6 204.7 148.7 63.8 69.3 102.8 106.0 228.6 48.6 53.9 251.4 246.4 224.0 271.6 167.1 245.1 70.6 91.2 115.3 146.9 69.1 69.5 58.9 70.9 59.9 195.0 36.6 110.1 128.1 118.2 100.1 46.4 72.3 171.0 68.3 118.6 163.0 50.1 44.8 334.5 172.7 132.3 182.9 144.4 80.4 66.9 47.8 222.2 58.6 167.3 10.5 6.6 3.7 15.6 10.6 7.5 12.3 10.2 12.7 7.1 11.5 4.9 7.6 2.6 13.4 27.3 10.8 13.0 9.7 475.5 483.4 433.2 406.8 351.2 408.7 567.9 490.6 509.2 526.1 552.3 533.2 147.9 70.5 48.2 124.4 45.1 74.8 55.4 53.1 42.7 392.2 34.7 36.2 921.5 48.6 53.4 80.9 625.5 33.8 54.6 43.7 27.4 97.8 116.2 78.2 143.2 110.4 28.8 21.6 63.7 65.3 81.0 105.5 39.8 93.4 27.8 81.6 50.0 57.3 38.0 47.1 71.2 31.7 34.6 28.3 50.5 38.8 77.0 40.0 78.2 95.5 72.0 82.8 47.4 77.9 167.2 92.0 28.0 103.0 47.2 89.0 37.1 39.2 43.6 97.5 72.3 149.0 119.0 65.6 64.3 58.7 69.6 22.4 60.5 137.4 39.5 44.7 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 146.2;Late spermatids: 282.5;Proximal enterocytes: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.8;RPMI-8226: 40.2;RT4: 47.0" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 37.5" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 8.7 55.9 3.1 8.8 3.0 9.4 14.2 0.5 4.4 18.6 0.0 44.6 30.9 3.4 11.5 102.4 7.6 7.5 2.5 2.9 2.2 17.3 6.7 23.8 7.9 0.6 0.0 5.4 47.7 38.9 33.3 5.6 0.2 16.7 24.4 2.7 49.5 15.5 1.2 74.1 40.1 1.9 0.1 16.1 24.1 40.0 4.2 6.9 18.9 1.0 12.4 12.2 39.3 2.7 31.4 0.3 0.7 0.5 2.4 11.2 4.3 3.3 0.4 0.3 0.8 22.3 28.4 7.0 2.0 2.5 4.6 24.4 0.3 63.8 0.7 20.0 7.9 0.2 1.2 22.8 4.0 0.4 2.2 9.2 25.9 4.3 1.0 4.5 4.1 1.2 0.6 9.4 0.9 12.7 0.4 2.6 0.4 30.9 0.4 21.0 0.5 40.2 11.6 47.0 30.5 0.7 2.5 0.5 0.2 1.3 33.0 4.1 6.3 2.4 0.4 1.0 0.7 0.8 12.7 2.3 0.1 1.3 0.2 7.6 0.4 6.5 18.3 0.1 12.3 13.9 14.5 15.4 0.1 22.0 12.8 14.4 4.6 3.8 0.1 0.2 38.0 8.6 3.1 3.0 0.5 4.4 2.9 2.2 0.6 0.0 0.2 0.1 4.2 2.7 1.5 28.9 33.0 1.0 16.4 27.3 43.5 24.9 15.4 0.7 58.8 17.7 1.7 25.8 27.3 29.5 6.2 55.3 14.9 146.2 15.6 56.9 110.3 9.1 2.8 2.1 65.5 0.0 10.0 115.9 11.8 5.0 32.1 26.2 2.5 21.1 1.1 1.7 40.3 0.0 6.7 83.2 34.6 6.8 3.3 282.5 7.2 8.8 17.8 3.7 14.2 2.1 21.6 1.5 1.2 103.6 102.2 9.8 11.4 37.1 178.4 11.5 3.7 2.4 0.0 2.2 3.4 56.6 2.9 62.6 53.3 32.3 18.5 2.5 93.0 59.9 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716340-143722458 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 54.9;fallopian tube: 46.7" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 62.5;Respiratory ciliated cells: 107.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.6;HeLa: 20.7;MCF7: 14.3;T-47d: 14.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 1.6 0.1 3.3 0.2 4.0 0.0 1.9 1.7 8.1 6.9 54.9 1.0 0.3 2.5 2.4 1.1 46.7 0.2 0.6 5.0 3.6 10.5 0.3 12.1 0.4 10.2 14.5 0.9 4.4 9.4 6.9 0.3 7.0 2.2 0.2 0.0 2.2 1.7 0.1 4.0 0.8 0.4 6.6 0.7 0.8 11.4 6.4 1.1 16.1 0.0 0.2 0.5 2.1 3.0 0.4 0.6 1.9 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.5 9.6 0.0 1.6 0.0 0.0 5.5 0.1 0.2 0.0 1.0 2.0 0.0 20.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.2 3.4 0.0 0.0 14.3 0.0 0.0 2.5 1.2 1.2 0.0 3.7 0.5 1.0 1.6 3.6 5.1 0.0 3.3 0.0 0.2 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 1.7 8.1 5.0 3.6 10.2 14.5 7.0 6.6 6.4 3.0 0.1 0.0 6.4 0.0 0.1 0.4 0.3 5.7 0.0 0.0 1.0 1.3 0.7 0.0 11.8 0.0 0.0 0.0 0.0 0.1 0.0 1.1 13.8 62.5 0.5 0.3 0.0 0.0 0.2 0.0 0.7 0.8 0.0 1.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.6 16.2 0.0 0.0 11.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 1.4 107.9 0.0 0.0 0.4 2.2 2.3 0.9 0.0 0.3 0.1 0.2 0.1 0.3 0.1 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;parathyroid gland: 51.0" "Cell type enhanced" "Detected in some" "Astrocytes: 202.7;Excitatory neurons: 105.2;Inhibitory neurons: 58.5;Late spermatids: 66.4;Muller glia cells: 62.6" "Cancer enriched" "Detected in many" 4 "glioma: 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HeLa: 3.3;NTERA-2: 2.2;SCLC-21H: 11.6;SH-SY5Y: 2.8;SK-MEL-30: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 0.9 26.8 56.5 0.2 79.9 0.0 0.8 56.4 46.0 1.5 28.0 6.8 0.6 0.8 3.1 2.3 1.5 1.8 22.1 41.6 57.5 3.3 4.5 2.3 0.0 65.4 70.0 2.9 1.4 51.0 17.8 2.6 56.7 5.0 0.8 22.6 0.9 9.8 1.5 1.3 1.6 1.8 48.8 0.1 2.1 2.4 81.9 7.3 6.2 1.5 0.0 4.6 1.3 38.7 0.0 0.0 1.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.1 1.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.6 2.8 0.0 0.8 1.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 79.9 56.4 46.0 41.6 57.5 65.4 70.0 56.7 48.8 81.9 38.7 0.4 9.6 0.0 202.7 0.0 0.0 0.4 0.0 0.0 11.4 0.9 1.1 22.9 1.5 0.0 0.0 0.0 4.6 0.0 0.0 5.9 0.9 30.1 0.0 0.0 0.3 0.0 0.0 105.2 0.0 0.3 1.0 0.0 0.0 0.0 0.7 0.0 1.0 0.4 5.0 58.5 0.0 0.0 0.0 0.0 66.4 0.9 0.1 0.0 7.5 0.0 62.6 0.0 18.6 1.9 0.4 0.0 1.5 0.0 0.7 0.0 0.2 0.0 1.0 0.0 1.0 0.7 0.8 0.6 0.0 0.0 1.8 0.0 0.4 0.0 0.1 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 16.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "HDLM-2: 211.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008910, HPA072462" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nuclear speckles" "CAB008910: , HPA072462: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 19.3 21.1 28.4 18.4 32.6 21.3 17.5 36.5 41.4 17.7 7.2 22.4 18.5 15.3 16.2 15.4 15.3 13.9 25.7 34.2 25.8 21.1 17.7 19.5 19.9 25.7 19.7 14.6 45.7 30.1 12.9 19.7 26.4 20.0 26.4 21.4 19.1 21.6 40.8 11.7 19.3 19.9 16.9 16.6 22.5 17.8 22.2 22.5 26.7 34.8 21.1 17.4 11.1 29.8 52.7 42.7 37.0 46.5 35.7 39.3 79.4 49.6 43.5 40.5 40.5 56.4 36.7 55.9 83.1 52.6 89.3 39.6 38.4 82.8 47.5 211.8 36.9 23.2 46.8 40.3 27.1 49.0 39.2 29.3 36.5 39.5 38.0 42.5 48.9 43.0 26.2 39.5 55.9 68.9 49.2 20.4 25.8 64.8 25.0 46.9 62.7 26.9 30.8 49.7 42.5 29.9 58.2 55.8 40.4 45.8 56.9 41.7 35.5 48.3 49.2 69.3 75.2 28.2 35.6 37.9 51.5 44.8 32.9 16.3 0.5 2.2 1.6 1.1 1.6 0.8 1.2 1.4 0.8 1.3 0.8 0.9 0.7 1.2 2.3 1.2 2.7 0.3 28.4 32.6 36.5 41.4 34.2 25.8 25.7 19.7 26.4 16.9 22.2 29.8 20.5 32.1 14.4 26.1 10.5 10.1 7.0 6.5 9.1 21.9 16.8 12.2 27.6 12.8 8.5 9.2 16.7 15.3 20.5 20.7 5.9 8.0 1.2 17.6 14.2 12.2 16.7 9.5 62.5 16.0 23.3 11.1 15.8 18.6 11.4 14.5 12.5 16.7 11.7 13.5 64.3 17.9 4.1 24.2 20.5 3.1 10.5 15.0 5.4 31.9 13.9 11.4 15.5 25.1 32.9 13.1 12.3 13.5 15.6 10.2 13.4 11.0 6.9 14.8 13.1 13.5 13.7 17.0 17.1 9.4 11.4 17.8 14.7 8.2 15.4 8.8 MAPKBP1 "KIAA0596, NPHP20" ENSG00000137802 "Mitogen-activated protein kinase binding protein 1" O60336 15 41774434-41827855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 204.3;Excitatory neurons: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030832, HPA030833" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA030832: AB_10601869, HPA030833: AB_2673628" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (6.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (9.84e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.08e-3)" "unprognostic (6.03e-3)" "unprognostic (7.94e-2)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" 6.2 10.5 10.9 4.6 12.4 4.4 7.7 31.1 13.7 11.1 10.1 10.2 9.6 9.9 4.5 18.6 10.4 4.6 6.4 9.9 8.5 7.1 4.1 6.0 3.9 9.0 8.0 15.1 5.5 4.2 12.7 5.4 9.0 8.9 3.6 9.0 7.5 5.9 5.1 24.2 9.9 9.0 5.3 8.0 9.3 34.4 9.1 6.3 13.4 3.7 6.8 12.2 12.0 10.2 7.4 3.8 10.0 9.5 10.9 10.8 6.9 10.1 25.5 9.1 6.6 7.6 2.7 1.8 8.1 8.3 12.5 17.2 9.8 28.5 6.5 6.7 2.7 7.3 12.8 2.6 4.7 4.7 14.5 5.6 22.3 14.3 25.9 14.8 13.4 11.9 4.6 3.4 12.9 1.5 4.0 4.2 1.1 4.3 7.6 4.3 7.2 0.7 5.3 8.1 11.3 6.3 5.7 5.9 4.5 10.2 7.1 3.7 10.6 13.0 6.2 12.4 10.0 7.3 12.7 4.3 8.7 6.3 11.0 1.1 0.4 0.3 0.8 0.1 0.6 0.4 0.4 0.3 0.5 0.4 0.6 0.5 0.1 0.6 0.5 0.1 0.2 0.5 10.9 12.4 31.1 13.7 9.9 8.5 9.0 8.0 9.0 5.3 9.1 10.2 7.1 6.4 10.3 33.0 3.5 54.7 10.0 8.6 36.5 14.5 5.4 8.9 3.4 2.8 7.3 3.7 204.3 6.8 5.6 4.0 0.0 3.0 15.7 10.9 7.1 9.5 4.8 0.8 62.2 3.7 4.4 5.8 9.2 8.9 1.3 12.2 5.3 2.6 3.9 15.2 55.1 1.7 4.1 2.5 6.1 27.1 7.2 5.0 8.8 33.7 4.2 4.4 3.1 34.7 51.9 4.6 1.8 7.9 5.1 12.5 8.1 0.5 13.0 8.9 13.1 7.8 5.7 12.7 4.2 27.7 53.6 5.3 5.8 8.0 2.5 15.2 MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.6;retina: 27.5" "Group enriched" "Detected in some" 4 "B-cells: 21.4;Hofbauer cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.3;myeloid DC: 44.2;naive B-cell: 35.8;non-classical monocyte: 45.4;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 7.1;U-266/70: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: AB_1853573, HPA048024: " "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 6.4 3.5 7.8 21.5 8.1 3.9 2.7 3.6 7.7 3.1 1.8 3.5 3.9 2.5 0.7 3.0 2.8 5.3 1.7 6.6 10.1 1.8 4.1 8.0 31.6 8.0 8.2 2.7 2.8 0.8 2.5 9.9 6.9 2.3 4.5 27.5 3.2 1.2 1.0 4.5 7.0 6.2 7.0 25.8 3.9 1.7 12.1 5.6 2.1 1.0 25.5 7.7 2.9 14.4 0.6 0.5 2.1 1.2 0.0 0.0 1.3 0.9 0.0 0.0 0.0 1.2 2.4 7.1 2.5 0.0 0.2 1.0 0.0 0.0 0.0 0.8 0.7 5.0 3.0 0.5 0.0 3.1 1.6 0.0 0.0 0.0 0.1 2.8 0.0 1.3 1.9 3.6 2.4 0.7 1.8 1.9 2.6 0.2 0.9 2.0 0.3 0.5 0.1 1.1 1.0 0.9 0.6 1.0 0.4 1.4 2.9 0.5 2.3 0.8 1.4 0.5 1.7 7.0 2.5 1.9 0.9 1.5 1.1 0.0 41.8 25.5 0.1 41.0 0.0 42.3 0.1 0.0 44.2 35.8 0.0 0.0 0.3 0.3 45.4 16.5 0.0 18.4 7.8 8.1 3.6 7.7 6.6 10.1 8.0 8.2 6.9 7.0 12.1 14.4 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.7;neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 405.8;TIME: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 19000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: AB_2682613, HPA067595: AB_2732772, HPA069443: AB_2732133" "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 42.8 16.8 65.1 58.2 64.1 104.6 50.2 73.2 78.5 31.9 21.6 75.7 38.9 31.2 13.5 45.1 27.3 35.8 18.2 56.8 89.2 24.6 26.1 35.0 45.4 81.0 87.6 39.0 42.4 7.0 20.6 63.0 73.1 37.8 68.2 22.0 28.0 18.0 15.7 32.1 43.3 30.1 106.8 57.0 62.8 10.3 85.5 44.8 16.2 12.9 45.3 86.2 34.5 102.8 39.2 22.6 405.8 22.3 134.0 86.6 2.2 123.0 171.4 84.9 140.6 40.7 54.1 0.1 25.3 228.0 67.3 118.0 67.9 35.7 109.7 0.3 40.2 0.0 22.2 53.3 89.2 10.3 0.7 90.2 68.8 81.8 77.4 231.9 243.1 0.4 4.6 107.6 122.1 0.4 1.3 0.3 52.7 43.5 29.4 0.2 40.7 4.1 26.9 73.6 56.4 163.4 78.7 39.6 89.6 95.0 2.1 11.3 326.0 78.3 0.5 129.9 212.7 288.3 22.4 11.4 60.2 55.8 153.4 0.0 3.9 0.0 0.0 12.7 0.0 4.6 0.0 0.0 1.1 1.9 0.0 0.0 18.7 0.0 7.5 0.0 0.0 0.5 65.1 64.1 73.2 78.5 56.8 89.2 81.0 87.6 73.1 106.8 85.5 102.8 211.2 9.6 15.5 44.7 139.0 504.1 540.7 232.3 275.4 157.0 213.2 176.7 16.6 57.2 115.0 38.6 29.2 7.2 5.5 629.5 37.2 144.3 55.7 111.2 444.0 271.6 336.3 2.5 33.0 229.9 11.2 372.6 135.1 130.4 2.5 526.1 236.0 8.8 371.6 84.1 21.0 369.4 126.1 286.3 605.5 35.7 120.5 381.3 273.9 60.0 447.2 315.5 2.1 194.5 9.7 208.1 223.1 67.0 105.2 380.1 89.9 6.9 145.0 37.7 39.5 89.8 222.8 22.7 16.2 326.3 638.5 29.4 22.3 62.3 352.3 620.2 MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 712.7" "Cell type enhanced" "Detected in many" "monocytes: 941.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 252.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 252.7" "Cell line enhanced" "Detected in many" "AF22: 1016.3;NTERA-2: 984.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Supported "Nucleoplasm,Actin filaments,Cytosol" NA Yes 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "CAB020787: , HPA030528: AB_2673514" "unprognostic (8.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-3)" "prognostic unfavorable (1.78e-6)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.50e-1)" "unprognostic (8.16e-3)" "unprognostic (1.08e-1)" "unprognostic (3.22e-2)" 63.4 59.9 363.5 82.1 510.3 50.1 102.9 540.1 438.2 81.2 206.4 108.1 61.8 93.4 155.8 15.1 72.2 97.2 55.0 343.0 408.0 51.1 38.7 40.0 176.0 631.5 504.7 358.0 23.7 6.5 22.9 42.9 534.9 84.7 116.5 37.9 75.9 49.9 8.7 28.3 56.1 42.7 467.9 63.1 132.8 139.2 466.4 166.0 110.3 11.0 199.5 77.8 27.1 712.7 82.9 73.3 1016.3 418.6 22.5 8.3 181.0 34.0 21.2 99.9 66.0 176.0 59.9 185.7 124.4 23.2 0.3 43.0 333.1 3.8 73.3 4.5 246.5 10.0 27.0 392.4 68.7 48.8 0.9 114.8 13.7 75.0 2.1 154.2 295.0 312.6 291.5 2.2 135.7 197.5 613.5 205.9 984.3 267.4 168.1 754.8 109.4 87.7 152.1 163.1 629.0 597.8 178.8 194.2 587.8 411.9 135.4 85.8 87.8 41.8 241.3 3.9 66.1 27.8 2.3 489.8 4.7 73.6 225.7 3.1 4.0 252.7 3.8 23.1 1.4 20.0 7.4 4.9 6.6 27.7 15.3 6.4 18.2 1.1 30.3 9.0 4.8 4.9 363.5 510.3 540.1 438.2 343.0 408.0 631.5 504.7 534.9 467.9 466.4 712.7 242.5 0.0 1.3 27.1 191.1 93.7 114.7 43.5 40.5 27.7 465.7 385.8 8.5 178.7 68.8 60.7 6.2 16.1 110.1 194.1 82.2 389.7 37.4 68.7 190.3 326.9 746.2 74.4 4.2 307.2 116.4 124.3 246.2 115.2 22.3 378.6 462.3 5.3 21.2 10.1 21.9 514.2 236.0 61.0 365.3 66.7 613.3 82.0 300.6 9.4 941.4 464.3 46.4 93.0 428.3 751.6 292.8 641.3 39.5 418.8 30.2 9.8 15.6 14.8 131.5 40.3 210.0 14.8 102.7 22.5 83.1 13.4 89.8 172.0 447.1 586.9 MAS1L "dJ994E9.2, MAS-L, MRG" ENSG00000204687 "MAS1 proto-oncogene like, G protein-coupled receptor" P35410 6 29486697-29487956 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 3.1;epididymis: 1.9" "Cell type enriched" "Detected in single" 62 "granulocytes: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017983 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA017983: AB_1849332" "unprognostic (3.66e-2)" "unprognostic (2.51e-1)" "unprognostic (2.30e-2)" "unprognostic (5.22e-2)" "unprognostic (1.65e-1)" 0.4 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 3.1 0.0 0.7 0.3 0.7 1.9 1.1 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.2 0.0 0.3 0.7 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 390.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Golgi apparatus, Vesicles" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favorable (2.12e-4)" "unprognostic (6.03e-2)" 48.1 36.3 57.4 43.5 63.2 105.1 41.2 74.6 62.9 61.0 44.8 51.1 41.3 51.1 29.2 75.8 67.2 36.2 52.8 55.0 59.4 39.5 36.8 51.6 63.7 65.5 61.8 56.2 29.3 31.3 32.5 39.8 65.0 52.2 31.8 23.6 43.5 38.7 43.8 55.3 51.7 39.5 59.4 66.3 39.4 21.5 62.1 63.7 42.7 54.0 55.1 51.3 68.7 65.3 117.1 40.4 27.8 44.6 73.4 58.0 35.4 39.9 62.3 47.5 58.4 29.1 86.7 88.1 33.1 48.8 45.0 60.4 63.4 52.7 37.3 84.5 40.5 143.4 29.9 32.0 90.9 56.2 390.3 67.6 43.5 42.7 54.9 71.9 54.9 71.8 66.8 42.4 53.1 63.9 140.1 217.6 36.3 71.3 70.6 75.2 42.7 47.3 49.2 38.8 61.8 38.2 49.6 60.6 60.4 25.1 58.0 71.6 69.7 47.8 55.8 42.0 33.6 50.7 43.6 61.7 56.9 56.1 46.0 667.6 141.9 540.8 125.7 126.4 140.1 115.7 147.5 130.5 119.9 114.9 151.1 127.9 305.1 126.9 120.3 114.6 194.0 314.2 57.4 63.2 74.6 62.9 55.0 59.4 65.5 61.8 65.0 59.4 62.1 65.3 45.8 28.9 27.4 31.0 74.5 170.2 66.0 63.3 126.3 28.2 59.8 43.1 27.4 32.9 42.0 18.4 20.9 38.4 79.1 116.3 52.8 38.8 45.5 38.1 43.6 59.9 44.3 40.4 50.7 31.4 43.4 46.7 32.6 36.0 62.8 38.2 71.0 23.8 59.9 47.1 43.3 49.7 38.7 81.8 66.7 115.6 77.9 147.2 56.9 32.8 67.1 47.3 69.0 28.1 60.4 61.6 96.7 60.2 58.0 80.3 100.6 66.4 32.9 16.9 138.1 47.4 76.3 43.2 28.4 84.8 180.6 54.0 83.9 25.4 29.7 76.2 MBD3L2 ENSG00000230522 "Methyl-CpG binding domain protein 3 like 2" Q8NHZ7 19 7049321-7051735 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nucleoli" Cytosol "HPA051259: AB_2681411" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MBD3L2B ENSG00000196589 "Methyl-CpG binding domain protein 3 like 2B" A0A1B0GVZ6 19 7018969-7021432 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Nucleoli" Cytosol "HPA051259: AB_2681411" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MBD3L4 ENSG00000205718 "Methyl-CpG binding domain protein 3 like 4" A6NDZ8 19 7037748-7040179 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Nucleoli" Cytosol "HPA051259: AB_2681411" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MBD3L5 ENSG00000237247 "Methyl-CpG binding domain protein 3 like 5" A6NJ08 19 7030578-7033011 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nucleoli" Cytosol "HPA051259: AB_2681411" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MBIP ENSG00000151332 "MAP3K12 binding inhibitory protein 1" Q9NS73 14 36298564-36320637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 316.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 30.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003388 Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 11: Alveolar cells - Smell perception" Cytosol "Nucleoplasm, Nucleoli" "HPA003388: AB_1079322" "unprognostic (8.79e-2)" "unprognostic (9.92e-2)" "unprognostic (5.07e-2)" "unprognostic (8.66e-2)" "unprognostic (9.85e-2)" "unprognostic (4.71e-2)" "unprognostic (2.71e-1)" "prognostic favorable (1.52e-4)" "unprognostic (5.24e-2)" "prognostic favorable (1.14e-4)" "unprognostic (4.65e-1)" "unprognostic (9.27e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-1)" "unprognostic (1.74e-3)" "unprognostic (1.09e-1)" 16.2 19.4 17.4 12.1 18.5 35.1 24.9 20.7 22.0 27.9 17.9 17.0 16.9 26.6 21.3 16.5 16.5 16.5 14.2 16.7 19.7 26.2 29.0 76.7 17.4 15.9 17.5 32.2 17.6 19.7 22.4 19.1 16.4 18.5 22.2 22.3 15.9 16.3 7.2 28.5 17.3 20.2 17.2 15.6 31.2 18.2 20.0 17.9 81.7 9.3 16.0 15.2 13.5 21.4 29.6 15.4 31.7 32.1 31.3 30.0 24.1 24.8 30.7 32.2 33.6 31.2 28.9 28.0 36.8 32.1 16.8 22.1 33.7 22.9 39.3 40.5 25.5 16.4 14.7 55.0 33.9 33.8 17.5 30.8 35.1 21.1 27.2 33.2 20.4 38.3 28.4 33.8 24.2 28.8 32.5 27.7 26.9 25.2 44.6 15.4 27.7 19.5 37.2 22.7 47.3 18.8 20.4 19.5 33.4 27.3 31.9 21.6 16.0 35.6 23.2 26.3 26.0 27.8 34.5 44.0 13.6 17.3 25.3 2.0 12.6 3.0 14.6 9.9 18.5 16.4 17.6 18.0 12.8 12.3 22.6 18.5 7.0 12.9 8.1 14.5 23.6 13.3 17.4 18.5 20.7 22.0 16.7 19.7 15.9 17.5 16.4 17.2 20.0 21.4 16.0 218.0 316.0 18.3 14.9 90.2 30.7 41.5 22.2 24.9 15.3 23.0 10.7 10.0 106.7 25.8 2.1 24.7 12.2 16.1 58.7 21.2 4.2 20.9 28.2 18.3 31.5 9.7 21.2 19.0 21.1 29.7 13.3 35.6 13.3 30.2 16.1 25.2 18.7 92.5 24.8 15.5 20.3 9.5 15.4 4.2 32.0 14.5 21.4 9.4 11.5 29.0 12.3 31.7 27.0 17.8 18.6 27.1 18.9 29.0 18.9 49.6 34.9 24.1 13.1 18.0 27.8 50.1 35.5 17.9 65.5 19.8 20.6 25.5 21.1 21.4 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 8.6 10.6 3.5 5.2 4.0 1.7 8.8 7.8 4.9 7.5 4.5 5.1 5.2 9.7 6.0 5.8 7.3 6.7 7.7 3.7 4.1 9.4 18.7 5.5 5.0 4.4 4.1 12.5 7.3 11.0 3.8 11.6 4.9 10.5 6.0 8.8 6.6 8.5 7.1 3.7 4.2 10.1 4.1 4.8 5.8 4.1 4.2 4.9 9.0 9.1 4.7 6.8 4.0 6.1 16.9 34.5 16.1 16.5 19.8 24.4 7.7 24.4 24.7 22.7 19.7 13.8 22.5 14.6 12.4 26.2 44.4 15.4 22.4 14.0 27.9 10.9 17.8 7.2 19.7 11.4 27.1 15.6 6.8 23.2 14.8 34.3 25.1 23.0 17.8 8.4 20.3 15.8 26.1 10.5 6.4 8.1 15.0 8.8 25.1 7.9 29.8 16.4 15.7 8.4 3.9 32.8 34.3 21.5 30.5 21.3 28.9 13.2 21.2 28.4 6.6 41.9 18.5 19.1 26.0 6.9 31.6 6.4 28.0 0.0 2.2 0.8 2.2 2.5 2.0 1.9 1.6 2.0 3.6 1.7 2.2 2.6 0.2 2.6 2.6 2.4 3.2 1.7 3.5 4.0 7.8 4.9 3.7 4.1 4.4 4.1 4.9 4.1 4.2 6.1 5.5 9.6 11.5 16.6 5.8 5.5 4.8 7.0 8.0 11.8 7.5 5.1 13.3 8.6 7.1 7.3 18.8 7.0 2.2 3.8 0.0 5.9 0.3 4.0 11.5 5.6 2.4 2.1 16.8 8.9 7.1 10.8 6.1 3.7 10.8 14.5 7.5 18.7 9.4 30.3 25.0 3.4 12.2 9.2 4.0 1.9 10.5 4.8 10.6 11.2 5.0 7.3 3.1 21.6 22.2 6.1 2.4 13.2 9.1 7.4 4.9 7.2 10.7 14.5 0.0 8.6 8.3 2.7 1.5 6.5 2.7 4.8 5.1 12.3 4.3 4.9 MCC ENSG00000171444 "MCC regulator of WNT signaling pathway" P23508 5 113022099-113488823 "Predicted intracellular proteins" "Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 70.6" "Cell type enhanced" "Detected in many" "Astrocytes: 170.7;Bipolar cells: 115.5;Inhibitory neurons: 128.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBEC3-KT: 52.9;hTCEpi: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037390, HPA037391" Approved Approved Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "Cytoplasmic bodies" "HPA037390: AB_2675451, HPA037391: AB_10671248" "unprognostic (6.60e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (8.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (5.21e-2)" "unprognostic (9.59e-2)" "unprognostic (8.02e-3)" "unprognostic (1.56e-1)" "unprognostic (1.74e-1)" "prognostic favorable (6.19e-4)" "unprognostic (1.70e-3)" "unprognostic (3.34e-1)" "unprognostic (2.47e-2)" "unprognostic (2.90e-1)" 10.0 2.9 8.2 4.8 11.6 0.4 8.4 12.4 8.8 18.1 1.7 3.7 2.3 12.1 5.1 12.8 12.1 5.0 12.7 6.4 15.0 5.2 18.9 6.2 4.6 15.7 24.5 70.6 3.1 32.9 3.1 10.7 11.0 10.3 3.1 14.6 7.9 12.8 8.3 20.8 2.9 9.1 11.6 5.0 4.9 3.5 18.9 4.7 4.3 6.3 6.4 12.4 11.9 8.2 0.8 0.2 13.5 1.0 10.9 9.8 12.8 2.2 5.7 2.4 2.8 0.5 12.5 0.1 14.3 1.0 6.6 15.7 8.2 52.9 1.2 4.6 5.0 0.1 4.9 3.6 3.3 0.7 0.3 12.9 34.5 6.7 24.2 12.4 16.0 1.6 0.1 20.3 5.2 1.0 0.2 0.3 7.3 0.0 1.0 0.2 11.8 3.5 0.2 30.7 5.7 12.8 11.2 0.1 29.8 4.6 3.7 0.1 19.3 8.7 7.9 14.5 4.3 5.9 0.1 0.0 24.6 0.1 9.7 0.0 0.1 0.0 0.2 0.1 0.6 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.5 0.0 0.0 2.7 0.7 0.0 8.2 11.6 12.4 8.8 6.4 15.0 15.7 24.5 11.0 11.6 18.9 8.2 50.2 0.0 1.1 170.7 1.8 37.6 27.3 27.3 23.9 115.5 11.7 8.8 16.8 11.5 10.4 3.7 56.3 0.8 8.5 0.2 0.0 3.5 12.5 11.5 50.1 32.1 4.8 0.0 29.5 1.4 2.4 30.2 4.1 25.4 0.0 22.9 24.7 56.9 2.3 37.0 128.7 0.2 12.2 2.9 12.3 34.3 21.1 2.2 16.0 72.1 3.2 7.1 3.1 34.7 13.2 4.6 1.3 27.1 5.4 8.5 0.0 2.2 7.1 9.2 0.0 22.0 13.1 7.9 9.3 33.4 47.2 1.2 8.0 24.9 0.5 16.0 MCM3AP "GANP, KIAA0572, Map80, SAC3" ENSG00000160294 "Minichromosome maintenance complex component 3 associated protein" O60318 21 46235133-46286297 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Immunity, mRNA transport, Protein transport, Translocation, Transport" "Acyltransferase, Transferase" "Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021527, HPA032103" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nuclear membrane, Cytosol" Nucleoplasm "HPA021527: AB_1853626, HPA032103: AB_2674152" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.31e-1)" "unprognostic (2.20e-1)" "unprognostic (1.72e-1)" "unprognostic (6.31e-3)" "unprognostic (1.48e-2)" "unprognostic (2.06e-1)" "unprognostic (4.17e-2)" "unprognostic (4.76e-3)" "prognostic favorable (2.05e-4)" "unprognostic (1.96e-1)" "unprognostic (2.81e-3)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (2.28e-1)" 16.8 12.0 10.0 20.3 11.5 19.7 13.6 8.9 10.7 14.7 17.0 15.1 14.0 16.5 8.3 14.3 15.2 14.2 15.1 8.5 7.8 13.0 9.7 16.0 21.0 10.8 10.4 17.6 15.4 16.9 9.2 16.3 9.5 14.2 15.0 12.8 13.7 13.4 41.3 13.8 16.1 17.1 9.4 19.6 15.4 14.1 11.0 21.7 16.0 28.7 21.5 13.6 11.2 14.6 38.0 36.3 41.8 45.5 33.1 41.4 38.0 40.8 48.1 37.1 30.2 33.1 21.9 53.6 32.9 43.2 40.3 21.9 55.9 34.0 32.7 55.7 50.8 87.9 35.0 25.9 29.6 40.6 47.7 31.7 28.7 51.2 35.2 25.4 40.7 31.7 107.3 39.6 43.3 21.1 43.5 26.8 72.3 40.0 30.2 56.3 26.6 48.9 17.8 34.1 35.2 37.6 52.4 33.7 39.0 31.5 46.0 41.2 51.6 39.1 29.7 33.1 31.0 71.8 86.2 33.0 35.3 38.0 51.8 0.6 2.0 1.6 2.3 1.9 2.4 1.1 1.3 2.6 1.9 1.6 1.2 1.3 1.2 1.1 1.1 1.6 1.8 2.1 10.0 11.5 8.9 10.7 8.5 7.8 10.8 10.4 9.5 9.4 11.0 14.6 17.3 9.6 18.9 28.1 21.3 7.0 7.1 9.0 22.2 21.8 13.8 13.0 4.7 14.3 12.7 11.0 20.9 11.4 20.6 17.5 1.9 11.3 3.5 16.8 23.7 14.8 12.0 18.5 28.0 14.2 11.7 12.8 27.0 17.7 8.8 20.1 11.7 18.6 15.4 16.8 34.2 19.2 10.2 19.7 8.4 4.3 18.3 18.6 10.6 34.7 24.3 9.3 16.5 37.2 35.3 15.9 8.6 14.3 21.6 14.0 13.8 6.6 15.5 21.7 19.7 17.9 12.9 19.7 15.0 21.2 10.4 9.3 19.1 16.0 17.9 7.9 MCMBP "C10orf119, FLJ13081, MCM-BP" ENSG00000197771 "Minichromosome maintenance complex binding protein" Q9BTE3 10 119829404-119892556 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013792, HPA038481" Uncertain Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "CAB013792: , HPA038481: AB_10794620" "unprognostic (1.26e-1)" "unprognostic (7.92e-2)" "unprognostic (4.62e-2)" "unprognostic (2.31e-2)" "unprognostic (1.72e-2)" "unprognostic (4.64e-2)" "unprognostic (1.31e-3)" "unprognostic (5.61e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.32e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.23e-2)" "unprognostic (8.24e-2)" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" 30.5 14.2 9.1 16.7 10.5 10.0 26.1 12.9 11.9 23.8 9.7 25.9 13.3 26.7 10.8 25.0 23.7 12.1 18.2 9.4 10.4 16.1 18.6 24.9 18.9 11.3 10.2 22.2 17.0 16.1 11.0 25.3 11.5 15.2 16.6 12.3 20.5 13.7 30.1 25.6 19.6 18.3 11.5 19.5 20.3 11.8 9.9 20.7 17.5 15.9 19.7 25.1 24.1 12.4 54.4 28.6 49.6 40.3 24.0 27.1 27.0 49.2 55.9 62.2 63.3 42.5 32.9 69.7 20.3 34.8 20.7 46.8 65.1 46.8 74.1 46.0 50.3 34.7 20.8 38.3 35.7 71.3 80.6 24.1 25.8 47.4 60.7 27.6 38.9 37.5 35.3 43.9 41.7 28.5 77.4 52.6 33.3 34.7 26.5 49.8 104.0 30.8 29.0 30.0 25.0 28.7 32.9 33.1 39.3 33.0 20.4 50.2 34.3 26.5 24.1 29.8 56.3 36.1 37.7 71.1 35.5 46.1 16.2 9.8 2.3 1.4 2.0 4.2 2.0 2.0 2.0 1.9 3.2 0.9 2.0 2.2 3.0 1.8 2.5 1.5 1.9 1.1 9.1 10.5 12.9 11.9 9.4 10.4 11.3 10.2 11.5 11.5 9.9 12.4 39.0 16.0 16.5 11.8 26.2 42.8 35.0 12.3 24.5 11.4 18.1 14.2 18.6 25.8 15.6 20.2 4.2 40.5 35.4 23.7 13.7 11.7 4.6 18.8 31.7 38.3 10.8 25.0 14.0 13.7 52.6 27.4 12.2 26.2 18.3 18.2 26.7 25.6 38.5 32.0 17.3 20.8 12.2 35.5 35.0 6.2 30.1 35.9 23.2 15.0 34.2 18.3 26.8 17.6 25.3 15.8 11.9 22.6 28.0 32.8 15.6 18.7 12.5 18.3 19.7 32.8 27.4 42.5 68.7 29.9 42.8 39.7 31.6 12.7 29.1 29.1 MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 109.4;Kupffer cells: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" 21.2 37.4 6.4 9.2 6.5 10.4 15.3 7.0 8.4 11.7 8.3 13.6 8.3 11.6 2.7 11.0 12.2 10.1 15.7 7.0 7.4 11.7 14.7 20.3 13.2 8.2 7.4 10.0 9.9 10.2 21.7 15.9 9.0 8.7 5.6 5.0 12.3 6.1 22.2 20.8 12.1 8.1 7.1 48.2 12.8 5.6 8.2 6.2 8.5 11.7 4.1 15.8 10.9 9.9 11.6 11.7 5.6 19.1 32.0 10.3 16.1 21.2 16.9 25.2 21.6 9.0 10.0 6.5 25.5 14.5 22.2 5.3 9.5 7.3 7.4 12.7 21.1 5.8 11.0 7.3 28.0 6.6 24.5 14.5 16.8 24.1 4.2 7.9 10.7 14.2 10.9 27.9 14.7 3.9 9.1 6.6 12.6 6.1 24.8 12.6 9.4 13.8 9.6 9.9 14.4 17.8 9.1 15.8 26.8 6.1 9.6 11.4 13.5 12.0 6.9 48.8 16.0 21.5 35.5 4.7 19.2 9.2 18.4 117.5 45.2 105.7 7.7 95.5 6.3 4.2 6.5 6.3 19.2 4.1 6.0 6.5 41.1 10.3 105.1 21.1 10.0 17.1 6.4 6.5 7.0 8.4 7.0 7.4 8.2 7.4 9.0 7.1 8.2 9.9 15.1 3.2 2.6 5.9 8.0 13.4 6.5 16.9 10.2 27.3 15.9 15.0 2.3 15.7 8.1 31.3 22.9 11.6 12.1 32.0 1.9 23.7 4.8 5.0 19.8 14.1 16.8 21.7 10.6 23.1 20.0 16.0 9.7 6.5 1.3 22.2 13.6 13.6 109.4 58.9 8.0 10.0 22.4 117.1 32.2 17.0 16.4 70.6 21.4 7.5 18.0 23.0 16.5 7.5 11.4 23.4 19.3 15.8 8.0 5.6 21.8 12.3 6.5 44.1 6.6 11.2 14.8 10.3 14.7 8.9 17.3 29.6 8.7 17.3 9.4 4.8 MCUB "CCDC109B, FLJ20647" ENSG00000005059 "Mitochondrial calcium uniporter dominant negative subunit beta" Q9NWR8 4 109560209-109688719 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 127.7;Exocrine glandular cells: 111.4;Extravillous trophoblasts: 91.9;Hofbauer cells: 106.8;Pancreatic endocrine cells: 67.9;Syncytiotrophoblasts: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 93.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048776 Enhanced Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Vesicles, Mitochondria" "HPA048776: AB_2680518" "unprognostic (6.12e-3)" "unprognostic (1.70e-2)" "unprognostic (3.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.70e-1)" "unprognostic (1.70e-2)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-3)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.35e-6)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" 10.2 2.0 2.6 18.4 3.0 10.6 7.6 2.1 3.4 7.0 3.5 5.3 3.8 8.8 1.5 6.8 5.8 7.8 10.5 2.7 4.6 3.5 2.2 7.2 32.2 4.3 3.0 5.6 1.5 1.2 3.7 6.1 3.2 3.0 6.3 3.7 4.9 2.1 1.4 6.2 7.8 8.2 3.7 13.5 4.6 3.0 5.2 31.4 3.3 3.5 25.7 9.2 7.5 4.6 26.9 11.7 6.4 32.6 6.9 18.1 23.9 23.3 14.2 24.9 22.1 0.6 21.6 93.0 4.6 20.2 13.8 7.6 24.1 14.0 21.9 59.2 18.4 11.3 11.6 1.6 12.1 23.6 0.4 11.7 3.8 15.1 13.0 17.7 33.9 35.0 3.3 59.4 19.2 34.0 54.1 0.4 28.2 4.8 15.6 20.4 47.7 10.8 29.6 12.1 25.6 11.1 24.2 73.4 7.7 5.3 9.2 1.2 23.9 9.8 12.6 51.8 40.2 22.3 16.4 22.7 29.9 4.9 6.9 0.4 51.4 0.8 18.9 32.2 26.6 43.6 79.1 56.5 49.8 50.7 114.7 66.2 3.6 65.0 24.4 35.1 74.9 92.2 2.6 3.0 2.1 3.4 2.7 4.6 4.3 3.0 3.2 3.7 5.2 4.6 21.5 9.6 5.2 0.0 19.5 0.0 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.0 2.5 5.5 0.0 127.7 36.0 0.0 0.0 25.2 0.0 7.0 5.9 11.7 0.0 0.0 0.0 111.4 91.9 15.1 0.0 8.9 1.3 9.1 0.0 0.0 106.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 14.5 0.0 0.0 0.0 0.0 67.9 0.0 0.0 5.8 0.0 0.0 0.9 2.2 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 73.5 28.2 7.4 0.0 0.0 MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717447 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006915 Enhanced Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites" No No "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Focal adhesion sites" "HPA006915: AB_1853669" "unprognostic (8.52e-2)" "unprognostic (4.32e-1)" "unprognostic (4.11e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.99e-1)" "unprognostic (4.39e-3)" "unprognostic (3.23e-1)" 11.3 7.0 2.7 8.6 3.2 13.0 10.9 4.1 5.2 12.4 3.3 11.0 4.9 13.7 8.5 6.2 12.3 4.6 9.5 2.4 4.1 8.2 9.7 9.5 10.2 4.5 3.3 16.8 10.8 8.6 12.8 7.4 3.5 10.1 6.9 14.1 9.1 8.2 11.0 9.4 10.9 8.9 2.0 11.3 8.4 28.2 3.4 14.5 16.4 5.8 11.3 10.7 9.3 3.6 36.7 11.1 47.4 34.8 6.3 10.0 23.0 14.8 10.0 25.2 21.3 22.7 8.5 37.7 17.5 17.0 23.5 20.2 63.0 28.6 34.9 29.9 65.6 43.4 28.7 12.5 4.1 27.1 16.9 7.9 9.2 48.6 27.3 9.0 11.5 25.7 61.0 36.7 19.1 14.7 14.6 20.0 20.6 8.4 7.8 33.2 24.7 37.4 11.0 10.7 39.9 23.2 11.5 26.2 13.5 29.1 21.8 16.8 13.8 24.8 26.4 19.2 26.3 19.3 21.6 34.5 7.8 63.9 34.3 0.1 0.1 0.1 0.6 0.1 0.3 0.4 0.4 0.5 0.1 0.7 0.5 0.5 0.0 3.2 0.1 0.7 0.0 0.3 2.7 3.2 4.1 5.2 2.4 4.1 4.5 3.3 3.5 2.0 3.4 3.6 9.7 16.0 13.0 10.1 13.4 4.5 5.5 5.6 15.9 11.5 6.8 8.6 7.6 7.2 5.7 5.5 8.4 7.9 11.0 2.5 3.9 5.3 4.7 8.0 8.7 9.7 6.7 14.5 8.3 6.2 11.4 11.2 4.1 13.7 17.1 12.8 6.1 12.0 6.7 5.0 8.1 3.3 12.2 6.0 5.7 3.9 7.8 7.3 1.8 11.2 5.9 10.6 14.4 12.5 9.9 5.2 1.1 6.0 16.9 2.9 1.2 3.0 8.0 17.1 13.1 16.2 8.3 74.5 18.0 8.7 3.7 1.9 12.1 7.7 6.0 1.9 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808177-68850686 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 257.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 504.6;U-698: 517.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303, CAB079977" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB000086: AB_563872, CAB016303: AB_627920, CAB079977: " "unprognostic (1.16e-1)" "prognostic favorable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favorable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 14.0 11.6 5.4 10.4 10.0 28.6 11.9 7.4 7.6 13.9 28.0 20.7 6.4 9.5 7.1 13.0 14.1 12.0 6.8 3.8 7.4 9.5 26.9 14.3 13.8 9.9 8.5 10.8 14.3 10.9 5.0 16.4 9.2 11.3 21.9 14.2 9.6 11.5 18.6 10.9 7.5 12.4 6.0 11.4 10.0 6.6 9.2 15.6 15.4 12.9 17.0 15.1 10.8 12.8 18.7 42.1 43.5 22.6 55.9 51.5 223.4 49.7 50.3 26.2 41.5 26.8 8.4 188.6 13.5 34.7 7.3 11.0 31.4 504.6 42.1 51.0 22.0 35.3 36.0 115.0 55.7 32.6 31.0 77.8 46.5 101.5 69.4 26.9 73.7 32.1 37.1 45.4 50.8 28.0 43.1 10.7 36.9 10.1 8.2 149.4 31.7 16.2 16.0 146.0 34.3 20.2 32.0 25.0 11.3 88.8 58.3 21.4 82.3 20.2 38.0 16.8 18.5 68.2 47.7 517.6 31.3 12.8 81.2 6.1 5.4 5.2 4.1 4.1 3.7 4.7 3.5 4.1 3.0 5.4 3.6 3.5 19.2 3.7 7.2 3.9 4.1 3.6 5.4 10.0 7.4 7.6 3.8 7.4 9.9 8.5 9.2 6.0 9.2 12.8 23.1 32.1 56.3 26.1 36.4 15.6 30.5 42.6 22.8 26.8 21.4 17.1 20.9 24.3 75.8 25.8 33.3 47.5 32.1 19.3 13.7 19.5 2.5 257.4 34.5 22.0 25.1 29.9 28.8 24.2 28.0 31.9 28.5 74.8 32.9 33.2 15.7 45.0 18.3 30.3 32.9 23.4 32.6 49.0 25.0 2.9 19.3 44.9 12.4 37.5 35.4 27.8 10.3 25.6 71.8 22.4 20.1 15.1 117.7 39.8 15.8 21.3 141.7 35.3 19.7 30.0 32.4 17.3 20.0 59.5 22.0 94.3 31.8 49.4 20.9 82.0 MDN1 "KIAA0301, Rea1" ENSG00000112159 "Midasin AAA ATPase 1" Q9NU22 6 89642498-89819794 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.5;Inhibitory neurons: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 24.7;NTERA-2: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029666, HPA029667, HPA029668, HPA029669" Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoli, Cytosol" "Nucleoplasm, Intermediate filaments" "HPA029666: AB_10600888, HPA029667: AB_10696207, HPA029668: AB_10669868, HPA029669: AB_10670429" "unprognostic (2.00e-1)" "unprognostic (4.46e-2)" "unprognostic (7.62e-2)" "unprognostic (2.26e-2)" "unprognostic (6.14e-3)" "unprognostic (3.46e-1)" "unprognostic (6.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.51e-1)" "unprognostic (1.75e-1)" "unprognostic (1.77e-2)" "unprognostic (9.07e-2)" "unprognostic (2.54e-3)" "unprognostic (6.28e-3)" "unprognostic (9.22e-2)" "unprognostic (2.02e-1)" "unprognostic (6.09e-2)" 4.2 4.6 3.4 1.9 3.6 4.2 4.3 4.4 3.3 4.5 1.7 4.4 1.2 5.6 2.1 4.9 5.0 1.2 4.9 3.1 3.3 4.4 9.1 3.9 2.6 3.3 3.1 7.6 5.9 3.0 4.6 1.2 3.7 3.6 1.8 3.0 3.9 1.5 8.3 7.1 5.0 1.7 2.2 4.5 4.6 6.5 3.3 2.8 6.0 3.4 2.5 4.2 4.3 5.7 4.2 4.1 4.1 3.8 6.6 6.3 4.1 2.8 2.1 3.1 3.8 9.4 1.5 12.5 3.1 2.9 3.3 3.6 10.7 3.8 5.5 4.9 7.1 13.5 5.6 6.1 2.5 17.7 3.2 3.9 3.1 8.3 7.6 1.9 5.6 5.6 24.7 2.9 3.1 5.0 2.8 6.6 22.7 3.4 3.5 5.5 7.8 3.1 2.7 5.8 7.5 3.3 3.9 2.3 2.5 5.4 1.6 7.7 7.2 2.1 3.8 2.8 6.5 3.3 3.9 5.9 2.8 9.8 3.7 3.2 0.3 0.6 0.7 0.2 0.6 1.0 1.0 0.8 0.2 1.3 1.3 1.0 0.0 1.1 0.3 3.0 0.4 0.1 3.4 3.6 4.4 3.3 3.1 3.3 3.3 3.1 3.7 2.2 3.3 5.7 13.2 28.9 19.1 55.2 19.2 29.3 8.2 6.0 30.7 24.4 14.0 11.0 39.2 11.5 16.9 14.7 25.0 5.5 25.2 6.6 0.0 6.3 7.5 20.1 21.9 15.0 7.7 58.5 82.5 8.1 7.2 13.3 19.4 25.2 6.3 26.4 6.4 48.5 6.6 18.5 79.5 7.7 6.1 6.3 9.5 4.3 7.2 8.6 12.4 33.7 6.6 8.0 9.2 35.7 74.8 6.9 3.7 8.6 26.0 18.1 4.7 2.5 12.9 18.7 0.0 33.1 12.7 37.5 50.1 26.1 30.1 3.4 19.4 17.4 10.3 8.5 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Excitatory neurons: 117.1;Inhibitory neurons: 70.6;Kupffer cells: 74.4;Muller glia cells: 100.6;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Cell line enhanced" "Detected in many" "CACO-2: 139.4;OE19: 158.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 41.4 44.4 13.4 5.2 15.4 0.4 29.9 14.5 18.1 8.0 8.5 7.7 21.7 4.2 6.5 28.6 4.2 15.5 18.6 13.1 17.4 3.6 9.8 8.8 4.2 15.0 19.1 10.8 3.4 19.9 12.5 2.9 18.3 8.4 11.0 30.0 10.3 17.2 34.7 14.4 10.4 7.8 13.4 7.3 23.8 16.1 16.8 5.6 6.7 30.5 4.5 15.3 12.0 13.5 29.0 59.1 1.4 0.0 48.0 44.4 0.1 18.4 47.0 19.2 37.1 139.4 24.9 0.0 46.8 43.4 38.2 29.8 43.4 16.4 20.9 0.0 24.4 0.0 33.8 0.0 61.4 14.3 50.3 49.0 32.3 38.7 26.3 32.1 30.4 0.0 20.4 0.1 26.4 32.7 0.0 16.2 0.0 158.3 23.0 0.0 48.5 27.9 56.8 13.7 5.8 14.9 31.2 45.7 1.0 25.0 0.0 34.5 32.4 11.9 14.1 3.9 0.1 10.9 13.3 0.1 0.0 0.0 35.9 0.0 1.6 0.0 0.8 0.3 16.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 13.4 15.4 14.5 18.1 13.1 17.4 15.0 19.1 18.3 13.4 16.8 13.5 0.9 19.2 12.1 71.8 0.6 1.9 5.1 12.5 6.8 17.1 2.5 0.9 41.0 7.2 12.7 5.5 2.1 0.6 0.5 12.7 1.9 12.3 5.5 0.7 6.8 2.3 0.0 0.0 117.1 9.5 0.9 8.5 62.7 0.2 0.0 11.2 4.2 12.1 7.1 13.5 70.6 4.1 8.2 74.4 25.6 6.5 25.7 16.7 0.0 23.4 5.5 100.6 0.0 123.6 38.6 15.0 4.5 37.2 0.5 5.2 15.2 3.1 7.2 7.5 0.0 4.5 8.3 7.5 2.3 22.3 3.4 0.8 1.8 33.6 8.9 3.3 MEAK7 "KIAA1609, mEAK-7, TLDC1" ENSG00000140950 "MTOR associated protein, eak-7 homolog" Q6P9B6 16 84476355-84554033 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 40.4;Syncytiotrophoblasts: 47.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 56.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041020 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "Nucleoplasm, Nucleoli" "HPA041020: AB_10794184" "unprognostic (8.35e-3)" "unprognostic (4.27e-2)" "unprognostic (1.48e-1)" "unprognostic (5.45e-2)" "unprognostic (1.49e-2)" "unprognostic (3.39e-3)" "unprognostic (5.97e-4)" "prognostic unfavorable (1.03e-5)" "unprognostic (3.94e-1)" "unprognostic (2.85e-2)" "prognostic unfavorable (7.05e-5)" "unprognostic (2.92e-2)" "unprognostic (6.78e-3)" "unprognostic (9.87e-2)" "unprognostic (1.83e-1)" "unprognostic (1.56e-2)" "unprognostic (2.16e-2)" 3.0 2.2 3.5 3.6 3.0 1.3 4.7 2.1 2.8 4.6 3.4 4.8 4.1 4.7 5.6 12.8 3.7 4.3 2.4 4.0 2.0 4.5 3.4 4.1 4.5 4.1 1.7 5.1 2.6 6.4 2.0 10.8 4.2 4.7 4.9 6.4 3.8 3.8 3.0 7.2 5.4 4.2 0.3 3.4 4.0 2.2 2.3 4.5 4.9 2.1 6.4 7.2 6.6 4.2 29.1 20.0 17.1 9.2 7.8 13.3 8.1 21.1 18.8 21.2 6.1 11.5 34.2 4.0 11.1 40.8 15.5 31.5 4.9 56.1 27.7 2.2 4.2 3.2 9.7 10.0 9.6 2.5 9.6 9.5 23.9 19.8 25.8 17.1 9.0 11.1 5.3 4.7 14.3 6.8 2.2 2.5 5.2 15.1 7.0 9.0 4.3 1.3 18.7 15.9 5.6 4.0 19.1 13.5 9.4 17.9 19.1 3.9 22.0 14.6 6.7 7.8 8.8 3.7 6.7 10.6 8.8 1.3 5.1 16.9 2.9 4.0 3.3 2.4 3.1 2.8 5.6 4.6 2.5 2.3 6.1 3.8 2.3 2.8 3.2 0.6 8.0 2.5 3.5 3.0 2.1 2.8 4.0 2.0 4.1 1.7 4.2 0.3 2.3 4.2 5.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 40.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 10.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 47.1 0.2 0.0 0.0 0.0 MED21 "SRB7, SURB7" ENSG00000152944 "Mediator complex subunit 21" Q13503 12 27022546-27066343 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 228.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017177 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "HPA017177: AB_1857665" "unprognostic (3.02e-1)" "unprognostic (7.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (7.18e-3)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" "unprognostic (7.32e-2)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.74e-8)" "unprognostic (3.18e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-2)" 16.7 24.9 10.5 9.9 11.4 29.0 18.2 14.6 15.2 25.2 11.2 20.4 12.2 20.3 15.0 23.9 19.2 15.0 25.4 11.2 11.6 26.2 16.1 16.6 13.0 9.4 9.5 24.9 13.3 25.7 17.8 16.4 9.6 18.3 16.9 12.4 20.9 17.0 27.9 15.8 12.0 21.8 10.1 12.0 16.3 29.7 10.5 21.1 18.9 35.5 17.1 22.6 23.8 11.3 36.6 40.5 18.6 27.5 41.3 36.1 29.7 46.2 24.5 30.2 32.5 42.5 37.3 21.4 25.9 26.5 54.2 30.7 41.1 36.3 53.8 21.6 36.8 36.5 37.9 22.4 22.0 41.3 21.2 31.1 46.4 45.3 50.0 54.0 46.6 30.8 25.8 28.2 34.7 27.1 38.1 63.8 54.3 50.1 49.8 29.3 133.5 23.7 28.1 37.4 13.4 17.7 57.3 18.2 26.1 79.9 34.6 26.4 39.0 34.8 28.7 43.3 40.3 9.6 21.4 37.8 34.7 39.4 23.3 54.9 23.8 33.6 26.2 26.0 25.4 28.8 30.0 30.8 22.5 26.9 35.2 30.4 18.7 19.0 24.6 18.3 34.5 26.9 10.5 11.4 14.6 15.2 11.2 11.6 9.4 9.5 9.6 10.1 10.5 11.3 30.9 16.0 23.0 7.8 35.4 98.9 121.4 95.1 72.8 9.9 39.4 33.5 32.1 22.8 45.0 53.3 0.0 62.0 33.1 18.5 93.9 41.7 228.6 32.7 26.3 33.0 17.9 68.8 23.8 38.0 56.8 50.8 18.8 35.1 18.4 31.3 25.7 21.8 31.7 13.5 17.6 20.8 65.1 21.7 50.2 87.8 48.4 22.4 71.2 7.5 29.1 27.1 11.3 10.6 14.4 33.4 19.9 47.4 24.5 85.3 22.4 109.3 20.8 13.6 19.7 37.4 54.8 157.7 61.8 70.5 101.3 61.0 46.7 30.6 20.4 145.8 MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.9" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Late spermatids: 67.4;Spermatocytes: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057997, HPA071835" Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA057997: AB_2732618, HPA071835: AB_2686455" "unprognostic (2.02e-2)" "prognostic favorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (2.57e-3)" "unprognostic (1.42e-1)" "unprognostic (3.60e-3)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.99e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (5.50e-5)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.98e-3)" 4.5 3.8 4.4 3.8 4.0 11.0 4.1 5.1 4.7 4.0 4.0 4.1 2.4 4.3 1.8 5.2 3.2 2.3 3.2 5.0 5.1 2.8 3.7 4.0 4.9 5.2 4.7 4.7 3.9 3.5 3.6 3.2 4.7 4.2 1.9 2.0 4.5 2.4 6.9 6.4 3.6 2.5 3.6 4.7 3.6 35.9 4.5 4.4 3.1 3.2 4.6 3.9 4.6 4.2 11.1 4.2 3.8 8.3 4.8 3.8 11.1 6.3 4.4 6.7 6.0 6.3 6.5 17.6 6.5 4.0 2.1 8.2 5.9 6.3 4.6 13.0 12.2 6.9 4.2 5.1 4.7 7.9 6.3 4.6 6.1 5.7 5.9 4.0 3.6 9.1 11.5 20.7 4.2 11.1 8.4 7.4 9.0 5.2 13.4 8.7 5.8 19.3 4.0 4.3 10.0 5.4 5.5 5.3 6.4 2.7 3.9 10.3 4.5 8.5 6.8 10.4 8.5 14.3 12.6 14.4 6.0 10.4 5.0 0.7 0.1 0.1 0.5 0.3 0.1 0.4 0.0 0.2 0.2 0.7 0.3 0.0 0.3 0.4 0.1 1.4 0.7 0.1 4.4 4.0 5.1 4.7 5.0 5.1 5.2 4.7 4.7 3.6 4.5 4.2 13.7 3.2 12.7 11.4 11.8 14.1 5.0 3.8 11.4 4.2 14.3 12.2 1.1 2.8 3.0 5.5 10.4 6.2 15.8 5.9 3.9 4.4 65.4 12.9 7.7 6.1 2.4 5.0 8.6 4.0 11.1 7.0 5.6 16.6 1.3 5.8 4.2 5.6 5.0 5.0 7.6 4.7 2.0 8.5 10.7 67.4 6.5 9.9 1.8 1.9 4.9 6.0 4.1 7.1 8.5 6.0 3.0 3.8 15.9 6.7 3.6 2.0 3.5 6.4 0.0 17.7 8.0 54.1 19.4 11.5 10.7 16.8 11.0 6.1 5.1 8.7 MED27 "CRSP34, CRSP8, MED3, TRAP37" ENSG00000160563 "Mediator complex subunit 27" Q6P2C8 9 131852928-132079867 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 87.7;Oligodendrocytes: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007002 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" Cytosol "HPA007002: AB_1078574" "unprognostic (8.81e-2)" "prognostic favorable (1.59e-4)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" "unprognostic (9.57e-2)" "unprognostic (1.32e-2)" "unprognostic (1.55e-2)" "unprognostic (6.07e-2)" "unprognostic (6.63e-3)" "unprognostic (1.63e-1)" "unprognostic (8.59e-3)" "unprognostic (5.93e-2)" "unprognostic (7.45e-3)" "unprognostic (9.16e-2)" "unprognostic (1.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.60e-2)" 14.6 14.7 20.4 10.1 22.7 18.4 14.8 19.6 22.1 14.0 17.6 16.6 8.3 19.0 23.5 17.0 15.2 9.6 18.5 22.8 19.7 14.6 9.9 14.0 15.4 20.3 19.2 12.8 9.0 15.8 17.1 13.1 19.6 15.5 11.1 13.7 11.3 13.7 20.9 20.5 11.7 16.7 19.3 14.2 12.9 18.2 19.3 28.2 13.3 14.4 14.1 17.3 13.7 21.7 33.1 29.8 40.9 32.0 28.4 24.7 33.3 34.7 48.8 73.9 58.8 53.0 29.4 31.7 21.5 39.3 48.1 60.9 54.5 51.8 46.8 34.6 36.1 24.5 31.1 31.3 42.7 43.2 33.4 28.9 37.9 57.9 61.4 22.9 41.4 52.1 36.7 29.0 57.2 57.8 52.4 30.8 40.6 36.5 62.6 44.7 51.0 43.6 31.0 17.8 72.5 28.9 44.4 22.7 26.5 25.7 37.6 22.1 29.5 71.8 31.4 52.6 51.5 10.8 32.0 57.2 40.3 33.9 50.6 5.7 18.1 21.2 26.5 28.6 21.5 16.7 20.2 26.3 28.3 19.3 16.5 21.8 7.0 27.8 24.9 29.2 30.0 18.7 20.4 22.7 19.6 22.1 22.8 19.7 20.3 19.2 19.6 19.3 19.3 21.7 10.4 16.0 7.8 55.8 12.0 6.0 14.4 28.2 18.8 24.6 3.8 6.7 6.2 2.8 17.2 12.9 18.8 33.1 14.5 4.7 13.7 15.0 14.3 8.6 10.3 12.4 5.3 6.3 87.7 16.7 20.4 12.0 10.2 8.3 10.8 12.6 6.8 5.2 17.5 21.9 63.3 5.5 18.3 3.1 5.0 8.4 14.3 9.1 7.2 33.7 10.1 25.0 3.1 69.4 130.0 16.1 2.0 17.0 13.9 7.0 2.3 7.8 9.2 20.0 6.6 16.7 17.0 24.2 28.7 10.9 5.1 54.7 15.5 18.8 4.8 10.1 MEF2B RSRFR2 ENSG00000213999 "Myocyte enhancer factor 2B" Q02080 19 19145567-19192131 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 39.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 29.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Daudi: 223.4;U-266/70: 217.6;U-698: 299.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004734 Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA004734: AB_10963939" "unprognostic (7.31e-3)" "unprognostic (4.06e-2)" "unprognostic (9.44e-5)" "unprognostic (5.07e-2)" "unprognostic (2.01e-1)" "unprognostic (7.19e-3)" "unprognostic (1.64e-1)" "unprognostic (1.78e-1)" "unprognostic (2.76e-1)" "unprognostic (1.98e-2)" "unprognostic (8.66e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-11)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (8.98e-3)" 3.0 1.8 4.4 13.9 5.4 2.3 2.6 4.4 6.1 4.0 4.4 3.1 1.8 2.3 0.7 2.2 3.5 1.4 2.2 4.5 4.7 2.7 3.8 2.6 39.3 5.2 4.9 3.9 1.5 0.4 2.6 1.0 4.8 4.5 1.1 0.9 2.6 1.3 1.0 2.8 4.9 1.3 4.3 8.8 2.6 3.2 5.2 1.8 3.4 0.7 31.5 2.3 3.3 6.1 2.3 0.5 1.5 2.1 1.3 2.5 2.2 1.3 0.9 1.8 2.2 0.0 3.2 223.4 1.0 0.9 0.5 2.0 0.3 0.8 0.3 1.0 5.1 1.4 0.6 1.1 2.8 1.2 2.0 1.0 1.8 1.1 1.6 1.0 0.1 4.2 0.9 3.9 0.8 3.9 1.6 1.8 0.2 0.2 12.8 4.6 0.9 5.2 0.5 0.3 0.3 1.8 2.5 0.3 1.7 0.0 0.0 2.5 0.7 1.1 4.0 6.9 1.8 217.6 24.0 299.5 2.6 3.9 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 4.4 5.4 4.4 6.1 4.5 4.7 5.2 4.9 4.8 4.3 5.2 6.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 29.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 1.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 9 "Adipocytes: 63.5;Endothelial cells: 41.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cell line enriched" "Detected in some" 14 "HeLa: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" 36.0 0.5 0.0 4.7 0.0 0.0 26.1 0.0 0.1 8.0 0.0 4.7 1.6 5.5 1.1 3.7 9.0 5.7 24.9 0.0 0.0 0.2 0.1 1.4 6.6 0.0 0.0 1.0 1.5 1.2 0.5 0.1 0.0 2.6 2.4 0.0 4.9 1.9 8.3 6.6 5.1 10.6 0.0 10.8 3.0 1.1 0.0 3.0 1.9 17.1 5.3 7.7 7.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 1.8 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.3 2.7 0.0 0.0 1.7 0.5 0.0 0.3 0.0 0.0 17.5 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.5 0.0 0.0 1.0 0.3 4.1 0.0 0.0 1.2 0.0 0.4 0.6 2.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 41.3 0.0 0.0 0.7 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.1 0.3 1.8 0.1 1.5 0.3 0.0 0.0 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 162.6;Kupffer cells: 119.8;Macrophages: 46.5;Microglial cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 8.6;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;Hep G2: 39.9;HUVEC TERT2: 38.4;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 59.8 22.8 13.5 28.0 1.5 15.3 18.0 29.3 12.6 44.7 10.9 12.3 11.5 26.3 8.4 15.5 12.0 7.0 22.0 22.5 11.4 21.0 13.6 13.1 23.5 22.3 12.6 9.9 21.2 15.5 20.1 22.4 14.1 7.9 16.6 6.4 16.3 3.2 6.4 14.3 14.4 18.4 30.6 13.9 17.2 30.1 6.8 10.1 4.6 8.9 13.6 9.4 22.0 1.0 1.7 7.6 17.3 0.4 0.2 12.3 0.0 0.2 1.0 1.7 35.1 2.2 0.1 8.1 0.1 7.9 0.2 10.2 0.0 1.4 1.5 5.5 7.0 0.0 39.9 0.3 0.2 1.5 0.5 0.0 8.9 0.6 4.0 38.4 1.5 2.2 3.5 2.9 1.8 0.0 9.1 4.8 1.1 6.0 2.9 2.1 3.0 19.4 23.4 0.3 7.2 0.2 0.5 3.2 2.7 0.0 0.4 5.8 1.0 3.4 0.1 0.0 3.1 4.8 0.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.5 0.1 0.0 0.2 22.8 28.0 18.0 29.3 22.0 22.5 23.5 22.3 22.4 18.4 30.1 22.0 8.8 3.2 27.7 162.6 1.7 1.7 2.9 0.3 1.8 0.6 2.1 4.3 2.7 2.8 6.4 0.0 2.1 3.3 0.4 1.2 1.9 1.1 2.3 8.0 4.7 10.2 0.0 0.4 5.0 1.0 1.1 3.2 0.5 12.1 0.0 3.8 28.5 9.2 25.5 0.0 7.0 2.0 0.0 119.8 1.8 2.7 5.0 46.5 0.0 124.6 1.5 7.7 0.0 10.6 0.6 1.2 1.9 6.8 10.8 2.9 4.4 1.9 1.5 11.3 6.6 1.5 9.2 0.6 1.5 0.6 1.3 18.9 1.3 3.5 1.9 1.6 MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 341.4;Extravillous trophoblasts: 279.3;Syncytiotrophoblasts: 436.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: AB_10674981, HPA041721: AB_2756310" "unprognostic (9.21e-2)" "unprognostic (4.50e-2)" "unprognostic (8.02e-2)" "prognostic favorable (2.31e-4)" "unprognostic (4.93e-3)" "unprognostic (2.32e-3)" "unprognostic (3.47e-2)" "unprognostic (3.09e-3)" "unprognostic (4.04e-1)" "prognostic favorable (1.12e-4)" "unprognostic (7.93e-2)" "unprognostic (3.05e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.88e-1)" 14.4 17.4 11.9 13.7 13.6 5.4 13.9 13.7 13.0 17.8 14.6 14.6 12.8 11.3 42.7 14.6 12.4 11.5 12.8 11.7 14.2 14.4 20.6 14.1 14.0 13.4 13.1 17.4 19.2 14.0 17.8 26.9 13.8 18.2 14.5 10.4 18.4 14.3 7.7 10.9 12.7 11.1 13.4 13.8 15.3 9.8 13.8 14.2 33.7 10.6 13.2 15.4 14.4 15.0 26.8 40.2 34.6 22.3 57.1 32.4 54.0 40.0 47.4 42.7 51.6 36.0 72.9 22.4 45.4 32.3 45.1 43.8 54.1 41.1 40.3 50.2 35.5 28.3 33.0 61.9 43.7 33.8 30.0 33.9 46.6 36.1 42.4 35.7 41.1 27.0 34.7 55.5 36.7 34.0 20.9 28.3 41.9 39.3 16.4 31.7 21.3 59.7 35.6 36.3 29.9 17.6 43.9 29.3 70.0 62.4 34.0 26.8 32.4 40.9 39.1 22.1 52.2 35.0 48.0 30.2 38.5 59.7 43.8 39.4 26.1 19.1 35.6 24.9 41.8 34.5 37.2 35.4 27.2 35.4 34.6 34.7 8.1 44.8 22.5 45.2 42.5 31.1 11.9 13.6 13.7 13.0 11.7 14.2 13.4 13.1 13.8 13.4 13.8 15.0 59.7 80.1 59.6 0.0 20.6 0.0 0.0 0.0 0.0 0.0 51.0 44.2 0.0 0.0 27.9 58.8 0.0 341.4 41.6 0.0 13.7 100.9 0.0 41.4 79.4 36.9 0.0 0.0 0.0 111.9 279.3 48.4 0.0 69.8 36.6 56.4 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.0 0.0 0.0 86.3 0.0 0.0 0.0 0.0 82.5 0.0 0.0 18.8 0.0 0.0 48.8 43.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 436.0 25.8 63.6 0.0 0.0 METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995659-99062809 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1627.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 8900 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: AB_2675777, HPA037998: AB_2675778" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "prognostic favorable (7.22e-4)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.72e-4)" "unprognostic (5.50e-2)" "unprognostic (8.51e-2)" "unprognostic (1.15e-3)" "prognostic favorable (9.31e-4)" 14.8 9.5 10.2 20.5 11.6 25.1 28.7 10.5 13.8 24.0 8.8 31.8 24.1 25.7 43.7 52.3 24.3 15.1 41.1 11.2 10.0 24.7 24.0 15.6 24.9 9.5 10.1 14.0 19.5 14.0 11.6 16.9 9.4 29.2 33.5 11.3 23.1 29.7 33.8 28.7 23.4 25.7 9.2 17.6 19.6 51.6 10.6 41.9 18.8 28.7 31.2 34.5 30.8 10.4 57.6 55.9 47.7 51.7 37.2 59.1 52.9 80.3 51.5 67.1 63.7 62.9 83.3 84.1 31.3 65.5 40.3 56.1 84.8 80.5 92.9 59.2 39.9 75.6 37.8 68.2 40.2 103.6 60.8 42.8 57.5 57.0 60.4 52.4 56.3 46.9 60.0 49.7 73.2 44.0 90.9 49.3 58.7 97.7 44.3 58.9 74.5 45.4 109.2 73.6 64.7 38.5 27.0 82.5 32.8 53.1 31.6 39.3 46.1 53.9 68.0 49.9 70.9 35.5 53.5 66.2 46.5 51.9 54.8 19.1 11.6 5.7 17.7 14.6 23.1 16.0 18.0 17.6 14.9 11.4 17.4 15.8 2.9 17.7 14.7 7.2 17.7 14.1 10.2 11.6 10.5 13.8 11.2 10.0 9.5 10.1 9.4 9.2 10.6 10.4 16.1 41.7 14.6 20.2 19.8 42.4 47.5 26.2 51.2 5.2 21.0 24.9 57.0 17.2 19.5 14.7 2.1 24.4 17.4 36.7 13.7 28.4 330.3 45.4 30.0 17.3 7.8 24.2 22.6 29.4 70.5 15.3 22.4 60.9 3.8 16.9 12.8 21.4 17.2 3.3 15.0 23.3 24.4 20.2 16.2 1627.3 19.3 17.4 16.0 14.0 13.9 10.6 25.7 17.6 22.3 28.0 30.8 22.6 17.8 34.4 25.3 31.6 17.2 3.7 26.3 11.5 21.7 15.7 41.6 54.3 38.8 7.7 23.6 18.1 36.2 46.9 METRN "C16orf23, MGC2601" ENSG00000103260 "Meteorin, glial cell differentiation regulator" Q9UJH8 16 715118-719655 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 299.3;choroid plexus: 238.6" "Cell type enriched" "Detected in many" 5 "Muller glia cells: 1153.9" "Cancer enhanced" "Detected in all" "glioma: 69.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 178.2;PC-3: 133.1;SK-MEL-30: 93.5" "Region enhanced" "Detected in all" "cerebellum: 612.9" HPA051164 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA051164: AB_2681369" "unprognostic (1.60e-2)" "unprognostic (3.49e-1)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (7.49e-2)" "unprognostic (1.82e-1)" "unprognostic (2.59e-1)" "unprognostic (8.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.12e-2)" "unprognostic (3.32e-1)" "unprognostic (5.03e-3)" "unprognostic (3.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.09e-1)" "unprognostic (2.17e-2)" 16.1 36.3 238.0 4.0 233.8 1.5 14.1 203.7 299.3 15.5 238.6 30.7 4.1 17.3 3.0 10.4 37.0 2.5 56.8 209.7 210.3 29.2 49.9 16.8 2.1 258.1 239.0 5.2 46.1 5.5 88.0 3.7 208.5 25.4 1.2 3.0 25.2 13.1 23.3 11.9 12.0 2.9 244.4 12.3 22.2 15.3 258.3 2.4 30.6 5.1 1.8 20.5 11.3 237.4 8.9 73.4 14.2 72.4 24.6 13.8 22.9 17.5 8.7 6.9 4.4 11.0 21.5 1.5 39.6 12.4 26.3 32.6 2.1 17.0 1.1 4.7 32.0 2.9 13.3 57.1 15.1 6.5 9.2 33.3 18.3 2.1 4.2 21.3 2.3 20.3 5.3 1.7 5.2 178.2 2.4 22.0 5.2 9.8 133.1 24.3 16.4 24.4 18.4 2.6 22.5 28.5 6.9 18.9 93.5 1.6 28.6 12.6 8.0 19.4 36.8 22.7 15.4 11.0 3.3 1.7 30.3 4.8 46.6 0.0 0.1 0.2 0.8 0.3 0.5 1.2 0.4 0.8 0.0 0.1 0.2 0.5 0.0 0.5 0.3 0.2 1.0 0.1 238.0 233.8 203.7 299.3 209.7 210.3 258.1 239.0 208.5 244.4 258.3 237.4 46.7 0.0 2.2 91.4 8.5 3.8 17.1 3.3 0.0 45.5 79.5 75.8 16.3 48.6 1.8 16.5 14.6 0.6 26.7 29.0 50.9 8.4 8.0 230.7 54.8 21.5 27.4 2.7 6.6 5.1 2.1 15.1 5.6 14.4 0.0 2.7 20.0 39.5 6.4 70.7 5.7 10.7 2.0 7.8 6.5 25.8 11.1 6.6 10.6 8.4 1.1 1153.9 23.7 44.2 57.6 5.3 26.7 9.4 7.9 27.7 6.2 55.6 9.5 37.9 26.3 11.8 26.7 4.6 11.7 1.4 3.0 0.4 12.7 5.2 9.2 16.2 METTL15 "FLJ33979, METT5D1" ENSG00000169519 "Methyltransferase like 15" A6NJ78 11 28108248-28527041 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.2;Oligodendrocyte precursor cells: 132.7;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039885 Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "Actin filaments" "HPA039885: AB_2676725" "unprognostic (2.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-2)" "unprognostic (2.66e-2)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (7.93e-2)" "unprognostic (6.31e-3)" "unprognostic (2.28e-1)" "prognostic favorable (7.95e-5)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (6.58e-2)" "unprognostic (6.84e-3)" 4.3 8.1 4.8 4.1 4.5 2.3 6.2 5.5 5.4 6.1 6.1 7.0 5.1 5.0 5.7 4.6 5.7 4.5 7.7 4.9 5.4 7.7 9.3 4.3 5.3 4.9 4.8 5.9 4.4 7.0 4.2 5.1 5.2 6.3 6.9 7.0 4.5 5.6 8.7 5.1 5.1 4.5 4.5 4.3 5.4 3.3 5.2 5.2 7.6 11.2 5.3 4.4 3.3 6.2 8.8 9.2 9.3 7.1 11.3 18.0 6.5 10.6 8.1 10.6 10.9 6.3 5.9 20.2 6.2 8.8 6.7 7.3 12.3 10.9 20.2 12.5 10.8 6.4 6.5 7.3 12.6 12.1 5.6 10.2 16.0 5.9 15.1 11.5 10.3 6.7 13.7 8.9 12.6 6.0 8.4 7.4 7.2 9.2 6.8 4.5 20.2 7.4 15.8 5.0 8.2 6.7 8.8 7.8 12.7 8.9 15.4 7.4 7.8 9.6 7.4 12.3 9.4 6.0 7.6 11.7 13.5 12.0 10.6 2.1 1.4 3.7 2.2 1.0 2.7 3.6 2.6 2.9 1.7 1.8 2.8 3.6 0.6 4.4 1.2 1.8 3.1 1.5 4.8 4.5 5.5 5.4 4.9 5.4 4.9 4.8 5.2 4.5 5.2 6.2 16.5 12.8 24.3 130.2 21.3 44.0 38.1 37.1 23.9 13.6 21.6 15.0 14.3 14.3 20.3 11.0 18.8 11.3 28.7 18.2 11.7 10.6 34.5 19.6 24.7 15.7 9.6 17.0 96.8 11.8 14.1 23.5 16.3 28.2 5.1 18.1 12.8 15.0 10.4 13.5 93.9 17.6 10.2 14.2 50.7 12.6 10.8 17.9 14.2 105.9 6.1 8.7 19.6 132.7 146.1 9.9 13.3 8.2 21.0 57.2 13.0 14.9 18.9 16.1 6.6 60.7 23.2 17.9 10.0 17.4 35.7 8.5 35.5 21.3 16.2 53.1 METTL25 "C12orf26, FLJ22789" ENSG00000127720 "Methyltransferase like 25" Q8N6Q8 12 82358528-82479239 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 23.5" "Group enriched" "Detected in many" 4 "Astrocytes: 68.2;Excitatory neurons: 63.2;Inhibitory neurons: 58.4;Microglial cells: 45.9;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039534, HPA041207" Enhanced Uncertain "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Mitochondria, Cytosol" "HPA039534: AB_10794749, HPA041207: AB_10794406" "unprognostic (1.60e-2)" "unprognostic (3.36e-3)" "unprognostic (2.06e-2)" "unprognostic (4.15e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-1)" "unprognostic (5.73e-3)" "unprognostic (1.21e-2)" "unprognostic (5.20e-2)" "unprognostic (6.66e-2)" "unprognostic (7.00e-3)" "unprognostic (2.15e-2)" "unprognostic (2.59e-3)" "unprognostic (1.48e-1)" "unprognostic (1.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.44e-2)" 3.1 3.1 2.5 3.0 3.2 3.1 5.7 2.7 23.5 3.9 3.3 4.1 4.1 3.7 4.5 3.5 3.6 2.8 4.7 3.2 4.4 4.5 2.5 3.5 4.8 14.0 1.9 5.4 2.6 4.1 2.6 3.5 10.5 3.2 4.7 6.0 4.2 2.9 4.5 3.6 3.1 3.4 1.0 3.7 2.8 5.9 6.8 4.3 4.7 3.7 4.0 3.6 3.1 14.0 1.2 2.8 3.8 0.9 4.0 4.6 3.6 5.6 3.3 2.9 2.2 3.1 3.0 7.3 1.2 4.3 0.7 1.2 7.5 1.0 1.9 6.3 5.6 3.7 1.4 3.4 2.3 6.4 4.1 3.5 3.4 1.0 0.0 5.8 6.2 2.6 2.3 3.1 3.1 4.1 2.7 5.5 5.6 3.2 1.0 1.7 2.2 3.9 9.2 3.9 2.7 2.1 2.2 3.5 3.7 3.0 2.9 6.0 2.5 1.4 1.4 2.3 3.3 3.9 2.4 2.9 2.2 3.9 3.0 19.0 6.5 3.9 4.3 6.0 6.1 5.3 4.6 3.7 4.9 7.2 6.0 4.9 12.2 10.0 5.5 11.1 4.3 3.6 2.5 3.2 2.7 23.5 3.2 4.4 14.0 1.9 10.5 1.0 6.8 14.0 7.9 9.6 9.6 68.2 7.6 4.6 7.3 12.4 4.6 7.0 8.1 8.5 12.7 8.6 8.4 3.7 6.2 11.8 11.5 5.5 7.9 5.5 4.9 5.6 6.6 7.0 7.3 1.7 63.2 3.2 5.4 7.4 8.2 5.9 3.8 7.1 10.8 4.5 5.6 3.3 58.4 4.1 12.2 3.8 5.2 1.7 4.7 6.4 5.4 45.9 14.7 4.2 4.1 89.0 98.9 4.3 5.6 10.5 11.6 3.4 6.3 8.4 12.7 11.5 0.0 12.3 7.2 12.9 9.5 10.6 6.1 7.8 6.4 8.7 6.0 4.4 METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657473 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 414.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: AB_2682203, HPA056347: " "unprognostic (1.55e-1)" "unprognostic (2.18e-2)" "unprognostic (1.98e-3)" "unprognostic (5.43e-2)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (8.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.11e-2)" "unprognostic (7.57e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.65e-1)" 63.6 100.6 41.9 31.1 52.7 118.7 54.5 39.5 53.2 62.9 53.1 45.2 28.3 46.3 70.5 67.8 42.4 32.9 42.0 44.9 41.7 140.8 16.5 49.2 36.1 44.7 43.4 48.6 39.7 68.1 44.7 36.8 40.3 45.6 31.1 38.6 49.8 28.0 77.4 51.5 39.2 33.1 47.1 54.7 44.3 11.0 46.5 56.9 52.7 52.9 44.1 49.5 57.5 48.2 50.8 41.8 95.3 77.0 99.5 156.2 36.1 85.7 103.8 58.8 68.5 30.4 79.9 92.4 64.8 132.6 53.3 33.0 61.1 71.4 71.2 70.5 72.0 41.1 34.1 120.6 75.1 35.8 81.0 111.6 76.6 54.3 81.1 119.4 111.4 97.8 61.8 57.6 112.3 60.2 93.7 71.2 87.6 60.8 64.0 124.8 80.8 82.7 116.3 44.5 61.8 116.0 66.1 53.1 195.0 65.6 44.5 16.7 75.0 96.9 43.9 62.2 49.5 72.8 102.8 71.4 107.6 80.8 66.3 111.0 75.7 33.4 11.4 14.3 13.5 18.3 19.0 21.1 42.5 20.6 20.4 16.2 36.1 17.0 12.0 14.3 20.4 28.8 41.9 52.7 39.5 53.2 44.9 41.7 44.7 43.4 40.3 47.1 46.5 48.2 82.4 19.2 26.1 32.3 66.9 71.8 89.5 143.8 51.2 52.6 77.7 61.7 53.6 34.3 81.3 86.5 45.9 79.4 94.3 49.6 281.8 119.5 7.8 56.4 68.9 89.2 84.9 146.9 48.2 122.9 124.2 67.6 42.8 64.7 47.7 70.0 98.6 11.2 95.8 45.4 37.8 80.4 101.7 181.7 103.3 6.3 63.3 124.2 104.9 40.3 270.1 92.9 109.2 34.2 28.3 114.9 51.5 65.1 58.0 149.4 81.1 414.2 50.4 43.7 65.7 48.9 108.8 17.1 25.1 74.7 77.0 139.1 111.4 57.4 80.5 142.9 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 277.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.7;Proximal enterocytes: 224.5;Undifferentiated cells: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA 19000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 48.4 105.0 17.2 19.0 16.9 24.6 39.9 16.8 19.3 37.0 18.1 147.0 134.1 36.9 13.4 75.1 37.2 23.5 103.3 18.9 14.2 124.8 277.1 61.2 15.5 16.3 15.0 41.1 63.3 22.9 37.7 17.9 15.1 42.3 65.0 4.4 57.9 11.9 43.8 53.4 168.3 14.9 14.6 52.8 96.3 30.6 18.0 10.5 60.1 14.9 16.0 38.7 42.1 16.2 84.2 85.3 40.8 93.7 117.4 65.1 71.1 48.3 98.3 44.4 34.8 91.7 226.4 14.4 122.3 108.2 193.1 61.6 57.9 110.1 32.2 121.0 33.0 43.5 75.1 78.4 85.9 53.7 13.4 70.5 76.6 44.1 53.0 165.2 89.1 16.9 28.7 38.5 73.6 92.6 8.4 47.4 24.7 123.7 35.1 21.6 31.4 40.4 132.3 158.5 67.5 39.7 73.7 75.2 139.1 33.8 51.3 56.3 109.2 106.6 48.6 61.2 80.2 32.5 39.5 35.4 125.0 68.2 78.7 0.0 0.4 5.5 0.1 0.1 0.0 0.0 0.3 0.1 0.3 0.9 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.2 17.2 16.9 16.8 19.3 18.9 14.2 16.3 15.0 15.1 14.6 18.0 16.2 35.7 12.8 9.2 9.4 7.7 12.5 17.8 12.5 5.2 15.5 29.6 30.7 24.1 37.1 11.1 27.6 4.2 8.1 22.1 224.7 3.9 66.7 0.7 27.2 17.8 24.3 22.9 5.5 11.4 54.0 11.1 15.3 78.5 50.5 5.1 39.5 26.7 89.9 17.7 30.3 10.0 72.2 14.2 20.7 11.7 2.6 15.2 24.5 10.6 9.4 16.8 25.7 6.2 4.5 6.3 89.9 114.6 17.0 7.0 49.0 224.5 22.4 7.7 11.1 13.1 16.2 24.7 1.5 6.5 21.1 11.9 14.0 12.5 24.9 131.8 64.8 MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.7;pituitary gland: 3.1;testis: 4.7;thyroid gland: 6.2" "Group enriched" "Detected in some" 8 "Astrocytes: 876.3;Excitatory neurons: 988.4;Inhibitory neurons: 1438.9" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "NTERA-2: 6.0;SCLC-21H: 2.5;SuSa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016418 Approved Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Centriolar satellite" "HPA016418: AB_2732416" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" 0.3 0.8 1.7 0.0 2.0 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.0 0.0 3.7 0.0 0.1 0.1 1.7 1.0 1.8 0.0 0.1 0.1 0.0 1.0 2.4 0.0 0.1 0.0 3.1 0.0 1.6 0.2 0.1 0.5 0.0 0.6 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.7 2.3 0.0 6.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.2 1.4 1.0 1.8 1.0 2.4 1.6 1.1 2.3 0.7 0.1 6.4 1.1 876.3 0.0 0.1 0.2 1.5 0.0 11.2 0.0 0.0 10.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 123.9 0.1 0.1 4.2 0.0 0.0 988.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1438.9 0.0 4.1 0.0 0.0 98.9 16.1 0.3 0.0 34.7 0.2 0.5 0.0 32.2 17.2 0.4 0.0 4.1 0.0 0.3 0.0 0.1 0.0 1.8 0.0 0.4 0.2 3.8 1.5 0.0 0.1 0.0 0.5 6.2 0.0 0.3 MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B" Q3V5L5 17 76868404-76950393 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 12.0" "Cell type enhanced" "Detected in some" "Astrocytes: 16.0;Early spermatids: 7.3;Excitatory neurons: 26.2;Inhibitory neurons: 21.9;Late spermatids: 8.1" "Group enriched" "Detected in many" 5 "glioma: 2.6;melanoma: 7.1;testis cancer: 2.4" "Region enhanced" "Detected in many" "cerebral cortex: 12.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 32.1;SCLC-21H: 15.9;U-138 MG: 19.2;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: AB_2668423" "unprognostic (6.37e-2)" "unprognostic (9.16e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.28e-3)" "unprognostic (1.52e-3)" "unprognostic (5.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.46e-7)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.01e-1)" 0.2 0.2 2.4 0.2 2.1 0.1 0.1 0.0 12.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.0 5.2 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.2 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 1.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 3.7 32.1 6.4 3.4 0.0 0.0 3.7 0.4 1.3 11.7 6.9 0.1 0.7 0.0 2.5 1.5 13.7 0.2 1.6 0.2 3.0 0.1 0.5 0.0 1.7 0.1 0.0 0.0 0.2 0.1 0.2 0.0 1.8 5.2 2.0 0.7 0.2 0.0 0.0 1.5 0.1 0.0 1.8 0.8 3.5 4.8 5.6 7.1 8.9 0.1 15.9 6.1 5.5 2.4 5.0 0.4 0.2 0.2 5.8 19.2 20.9 0.3 6.3 0.0 0.0 0.7 0.6 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.1 0.0 12.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.0 0.1 0.1 0.1 0.0 0.0 5.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.1 0.1 0.8 0.0 0.0 26.2 0.0 3.2 0.2 0.0 0.2 0.0 0.6 0.7 0.0 0.1 0.0 21.9 0.0 0.0 0.0 0.0 8.1 0.6 0.0 0.0 2.8 0.0 0.2 0.0 5.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 1.1 2.4 0.0 0.0 0.1 0.1 0.2 0.0 0.0 MICAL2 KIAA0750 ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.5;Inhibitory neurons: 108.8;Late spermatids: 192.7;Peritubular cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 8.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-138 MG: 109.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 4.7 3.8 13.9 12.2 13.6 11.6 2.5 61.6 38.1 6.9 42.6 18.8 9.8 12.3 7.2 18.6 7.4 10.0 42.2 37.8 0.0 2.3 2.9 17.5 3.3 0.0 0.0 3.9 4.1 1.0 0.2 7.3 0.0 2.9 16.3 4.0 0.8 9.6 16.8 14.0 10.8 30.8 0.0 3.3 6.7 32.5 0.0 1.9 6.1 4.1 2.5 12.4 0.3 19.9 29.1 9.7 0.4 2.7 2.3 6.8 14.2 32.1 53.7 16.2 28.3 24.3 23.3 0.2 8.4 25.3 47.7 25.0 4.0 65.1 41.6 35.9 4.8 27.5 4.1 0.9 12.8 5.3 2.7 12.7 11.1 76.0 54.6 25.3 46.9 1.6 43.5 0.8 22.9 1.2 0.3 1.6 1.2 13.6 9.8 0.3 15.2 14.2 2.1 35.5 14.3 0.8 8.6 38.6 2.9 9.9 4.5 2.3 42.6 109.6 35.0 17.4 39.6 0.9 2.6 1.5 64.3 5.2 1.4 0.1 4.2 0.5 1.3 0.7 1.5 0.1 0.8 0.4 3.4 0.2 0.0 0.4 8.9 2.2 0.4 0.9 0.7 1.5 13.9 13.6 61.6 38.1 37.8 0.0 0.0 0.0 0.0 0.0 0.0 19.9 3.2 41.7 37.1 7.2 1.2 10.1 11.8 4.5 4.0 5.7 4.2 5.3 32.2 7.2 8.5 3.7 0.0 2.6 11.2 66.5 0.0 10.2 74.4 7.8 8.9 9.2 22.6 35.6 193.5 14.3 12.6 9.0 12.2 11.4 1.3 1.4 12.8 19.6 3.4 0.0 108.8 10.6 6.1 10.1 5.6 192.7 21.1 11.1 5.4 4.7 21.6 0.5 8.2 6.6 17.5 42.5 24.0 112.8 2.1 8.9 18.3 0.9 5.5 1.6 13.1 1.9 29.4 1.2 1.3 1.7 9.5 2.3 10.8 0.7 14.5 11.9 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 104.9" "Immune cell enriched" "Detected in some" 4 "basophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Cell line enhanced" "Detected in all" "WM-115: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 15.9 12.0 18.3 14.9 20.3 17.3 11.2 104.9 34.5 16.5 3.6 28.1 11.0 31.0 17.0 19.6 38.6 13.4 35.6 14.3 13.7 10.9 18.8 8.3 23.0 13.2 6.4 26.5 14.0 38.5 7.2 16.7 15.6 16.4 20.6 14.1 10.9 19.8 48.2 18.9 14.5 37.3 1.9 17.8 10.7 24.4 12.7 6.0 14.7 20.8 20.3 15.9 12.0 45.9 34.0 39.6 20.2 33.7 15.6 19.2 25.6 32.6 33.1 43.6 34.5 36.1 4.8 35.1 15.5 39.3 51.2 38.7 30.1 31.9 43.0 35.6 25.2 35.9 44.6 11.9 9.6 17.1 20.2 14.4 25.9 46.9 43.7 25.2 24.9 9.7 47.6 22.8 16.9 26.6 16.9 10.7 13.0 27.3 26.4 23.2 30.3 1.9 32.1 24.8 53.5 21.1 40.6 26.0 65.2 31.5 10.8 7.0 43.9 46.0 28.4 29.7 63.6 16.4 30.2 50.8 40.0 7.7 131.6 11.1 0.0 0.1 0.3 0.0 0.6 2.5 0.3 0.3 0.0 2.6 0.2 0.1 0.1 0.9 0.0 0.2 0.7 0.2 18.3 20.3 104.9 34.5 14.3 13.7 13.2 6.4 15.6 1.9 12.7 45.9 19.6 3.2 10.2 57.1 32.1 11.2 15.2 17.9 13.1 20.9 13.7 15.5 16.5 12.8 13.2 12.9 52.1 14.1 6.2 43.5 0.0 23.9 10.5 36.4 10.2 16.4 10.2 19.3 176.5 9.8 40.3 10.5 13.3 38.8 19.0 9.7 8.9 37.3 3.1 1.7 164.6 20.8 8.2 3.2 9.6 13.9 4.1 4.2 8.8 23.4 6.0 38.2 5.2 71.9 216.0 24.6 23.6 6.4 12.5 14.4 19.8 5.5 27.8 12.2 0.0 11.0 12.1 19.8 13.8 11.2 11.8 11.2 9.1 24.2 21.5 10.1 MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: AB_10793950, HPA051956: AB_2681671" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.08e-6)" "unprognostic (3.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-3)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" 9.6 5.8 8.2 9.3 14.8 6.2 10.2 15.7 10.3 18.4 8.0 38.6 6.4 28.4 3.1 46.6 13.6 6.4 10.7 8.7 9.8 8.7 7.0 11.7 5.9 19.7 16.8 4.8 18.5 10.6 4.4 17.3 17.4 17.0 4.6 0.8 17.8 24.0 10.8 36.6 12.5 19.7 14.1 7.2 44.0 10.8 15.3 5.4 10.0 5.2 7.1 25.4 26.0 22.2 25.4 13.7 13.0 15.4 10.4 11.9 59.9 32.3 17.5 34.8 25.3 17.3 13.1 10.8 10.5 22.2 22.7 65.0 9.1 69.9 17.2 21.2 31.3 5.7 11.6 16.7 24.0 11.6 11.8 11.3 101.2 42.5 70.1 10.4 22.1 4.9 8.9 8.1 22.7 10.6 2.9 6.7 5.0 12.9 12.1 16.6 27.4 6.1 8.1 53.0 9.6 8.5 19.3 19.7 20.2 15.4 10.8 10.9 34.3 61.1 47.3 37.8 27.5 9.4 3.7 7.2 55.2 5.8 29.0 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.3 0.5 0.3 0.5 0.3 0.2 0.5 0.5 0.1 0.6 0.1 0.4 8.2 14.8 15.7 10.3 8.7 9.8 19.7 16.8 17.4 14.1 15.3 22.2 10.9 0.0 7.8 1.3 4.8 7.5 10.1 12.8 23.9 0.7 7.3 7.9 11.9 7.2 9.5 5.5 0.0 31.0 7.8 7.7 1.9 10.5 18.1 11.3 5.4 12.2 3.5 1.3 0.7 10.2 26.3 4.3 27.5 6.8 1.3 5.8 6.4 5.9 8.7 5.0 4.4 3.9 6.1 4.4 3.4 28.8 1.8 4.3 1.8 1.0 7.2 0.7 7.2 2.5 17.8 15.4 2.2 4.1 6.4 13.6 4.4 2.7 6.0 0.7 0.0 3.5 9.4 5.5 2.2 27.2 9.1 39.4 5.2 1.5 3.7 15.2 MICB PERB11.2 ENSG00000204516 "MHC class I polypeptide-related sequence B" Q29980 6 31494881-31511124 "Disease related genes, Predicted membrane proteins" "Adaptive immunity, Cytolysis, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "dendritic cells: 10.3;Erythroid cells: 10.5;Hofbauer cells: 11.1;Kupffer cells: 17.8;monocytes: 13.2;T-cells: 11.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 15.2;U-266/84: 36.5" HPA064618 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA064618: AB_2685301" "unprognostic (3.63e-3)" "unprognostic (8.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (8.44e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (7.04e-5)" "unprognostic (2.05e-1)" "unprognostic (2.61e-1)" "unprognostic (1.67e-3)" "unprognostic (2.28e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (4.94e-9)" "unprognostic (1.91e-3)" "unprognostic (2.80e-2)" "unprognostic (9.72e-2)" "unprognostic (1.21e-2)" 2.6 1.2 0.1 1.4 0.2 2.2 2.2 0.2 0.4 1.4 0.2 1.9 0.2 1.7 0.3 1.4 1.2 0.4 2.5 0.2 0.1 1.8 1.2 6.2 2.8 0.2 0.1 0.7 0.8 0.1 0.6 0.2 0.2 1.1 0.5 0.0 1.3 0.0 0.5 1.0 4.5 0.4 0.1 9.9 1.4 1.3 0.3 0.7 1.6 0.7 1.6 1.4 1.5 0.2 3.4 1.3 0.0 0.0 1.9 3.2 0.1 2.3 2.2 2.9 3.7 0.0 0.4 3.9 5.9 4.3 8.1 0.8 1.0 4.1 1.0 3.4 2.3 4.6 0.6 1.3 0.7 1.4 3.5 4.1 0.8 5.0 3.5 3.1 1.9 6.0 4.2 7.8 3.5 0.0 1.3 5.9 0.4 0.0 0.5 4.7 0.0 8.2 3.8 0.2 0.0 0.0 1.5 0.0 0.7 1.2 2.0 1.6 1.9 2.2 0.0 1.9 0.1 15.2 36.5 8.3 0.5 12.0 4.9 1.8 0.9 1.2 0.8 1.1 1.0 0.6 0.8 1.1 0.6 0.5 0.4 0.9 0.9 0.6 1.6 0.4 1.4 0.7 0.1 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.2 3.0 3.2 1.5 0.0 8.2 2.9 0.5 0.3 0.0 0.0 3.1 1.9 0.5 1.5 0.8 0.0 0.0 0.1 10.3 0.8 1.9 1.6 0.0 3.1 1.6 3.0 0.0 10.5 0.6 0.7 0.3 1.5 2.0 5.2 0.0 0.1 3.9 0.1 11.1 0.0 0.1 0.6 0.0 17.8 8.2 0.4 0.3 8.0 1.8 3.7 13.2 0.0 7.2 0.0 0.1 1.9 1.9 0.4 8.7 2.1 0.5 0.3 0.9 0.0 0.0 0.6 2.2 4.6 5.2 0.1 1.1 0.1 11.3 0.5 2.1 1.1 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Basal squamous epithelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 156.1;AF22: 132.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 5.9 2.5 6.9 5.0 7.7 1.7 5.3 17.2 5.0 7.0 6.5 17.3 5.7 8.9 4.9 7.0 6.4 6.8 9.3 7.0 4.9 7.3 4.2 6.5 2.2 3.6 10.4 4.4 3.5 2.8 4.2 6.2 4.9 10.4 10.6 12.3 4.9 12.9 0.7 2.9 5.8 12.3 2.1 1.0 3.8 3.6 8.2 2.3 4.2 2.2 3.1 11.7 6.2 4.4 33.2 156.1 132.5 16.7 8.1 9.2 14.6 16.2 17.8 19.7 20.7 31.0 9.7 10.6 6.5 21.9 58.4 22.5 11.0 15.1 23.0 1.3 11.0 2.7 24.3 1.1 2.8 0.3 1.2 12.1 7.0 16.1 15.8 20.4 23.1 5.1 2.1 3.2 9.6 8.0 5.3 0.5 32.7 5.1 10.0 3.9 28.9 0.4 18.7 36.2 7.1 3.5 7.4 23.5 10.1 42.7 19.2 0.2 13.7 7.2 1.0 34.1 17.0 2.8 1.2 0.4 13.5 0.3 31.3 0.5 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.4 0.0 0.1 6.9 7.7 17.2 5.0 7.0 4.9 3.6 10.4 4.9 2.1 8.2 4.4 16.5 35.3 20.7 129.3 0.7 21.4 31.5 24.7 82.6 10.7 8.5 13.2 4.8 8.6 19.6 23.9 18.8 9.1 1.3 22.6 1.9 13.4 2.2 39.8 8.9 25.4 12.1 2.7 15.5 8.7 26.9 16.2 10.7 38.5 1.3 13.4 69.9 4.0 1.5 69.0 44.3 9.0 2.0 2.5 5.8 7.9 30.1 1.2 3.6 23.4 0.0 37.0 0.0 66.4 59.2 7.3 17.2 41.3 0.2 8.2 11.3 1.5 19.3 2.9 6.6 3.7 3.3 0.3 2.4 36.1 10.1 20.0 0.8 9.7 20.0 49.2 MIEN1 "C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4" ENSG00000141741 "Migration and invasion enhancer 1" Q9BRT3 17 39728496-39730532 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 14 "OE19: 1667.9;SK-BR-3: 502.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056650, HPA061344" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "HPA056650: , HPA061344: AB_2684484" "unprognostic (2.48e-1)" "unprognostic (3.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-2)" "unprognostic (3.04e-1)" "unprognostic (1.17e-1)" "unprognostic (4.47e-2)" "unprognostic (8.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.17e-1)" "unprognostic (2.99e-2)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-3)" "unprognostic (2.22e-3)" 29.1 35.9 33.4 17.5 35.4 27.0 31.5 36.2 44.8 31.1 34.2 42.4 26.3 29.0 14.6 47.3 27.2 12.1 49.5 32.5 35.3 57.2 53.7 29.6 20.2 34.5 34.8 18.5 40.7 21.6 39.6 13.5 34.5 46.3 12.8 4.8 46.2 13.8 47.2 35.0 37.5 9.5 32.9 36.2 48.5 41.3 35.4 13.9 37.0 5.3 13.7 31.0 32.0 37.2 38.8 59.7 13.4 34.5 16.3 12.0 16.2 40.7 21.4 24.2 23.6 12.9 27.2 28.1 55.5 15.1 39.0 47.1 15.6 13.8 8.2 58.2 65.8 26.5 29.8 36.5 28.2 33.9 39.2 10.8 23.3 11.7 12.0 18.8 15.6 52.9 38.2 48.9 14.7 22.5 70.1 38.2 12.5 1667.9 26.4 32.2 23.6 56.8 12.2 21.8 43.6 41.7 40.8 502.3 70.7 12.0 66.1 48.1 41.5 16.4 41.8 78.9 47.1 62.3 62.8 55.1 64.5 41.1 32.4 138.5 76.2 107.3 80.1 100.9 43.4 109.2 56.2 72.3 54.5 88.3 43.9 63.1 132.9 58.7 104.2 79.4 94.6 119.9 33.4 35.4 36.2 44.8 32.5 35.3 34.5 34.8 34.5 32.9 35.4 37.2 59.8 44.8 64.2 7.8 60.9 60.2 138.1 185.1 95.6 25.7 127.0 114.2 59.6 82.9 129.3 99.3 4.2 150.2 69.1 226.6 303.3 137.0 136.2 81.6 48.7 58.9 188.8 72.0 11.0 176.1 74.4 50.9 76.5 77.3 81.8 43.8 54.7 118.9 148.0 35.3 9.6 178.3 254.3 101.3 42.8 76.7 42.3 81.3 138.7 12.2 80.1 90.7 130.7 4.5 20.8 216.8 283.7 49.7 54.0 194.8 188.5 224.9 122.1 17.3 46.0 31.5 61.1 108.5 68.0 131.7 70.3 266.1 65.4 51.7 128.1 204.0 MIF4GD "AD023, MGC45027, MIFD, SLIP1" ENSG00000125457 "MIF4G domain containing" A9UHW6 17 75266228-75271231 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051222 Approved Supported "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 6: T47d - Mammary gland" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoli "Golgi apparatus, Cytosol" "HPA051222: AB_2681393" "unprognostic (1.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.94e-2)" "unprognostic (3.82e-3)" "unprognostic (2.92e-1)" "unprognostic (1.31e-1)" "unprognostic (2.36e-2)" "unprognostic (4.21e-2)" "unprognostic (1.44e-1)" "unprognostic (8.15e-2)" "prognostic favorable (2.70e-4)" "unprognostic (2.18e-1)" "unprognostic (9.20e-2)" "unprognostic (9.88e-2)" "unprognostic (2.29e-1)" "unprognostic (7.12e-2)" "unprognostic (7.31e-2)" 29.7 22.5 15.6 18.7 17.7 43.6 23.4 16.9 16.4 22.2 12.9 24.1 12.6 23.1 8.2 28.4 18.2 17.3 23.0 15.1 16.5 24.5 17.6 25.4 33.2 17.3 17.2 14.2 27.6 21.5 11.8 12.3 18.4 16.4 15.1 6.0 19.9 14.4 63.2 32.8 25.1 16.9 17.4 35.7 19.5 17.9 16.6 24.5 16.6 26.8 27.0 23.7 21.6 18.6 25.6 43.5 8.9 20.3 17.9 5.4 12.7 6.2 19.1 13.0 9.5 14.4 29.8 38.7 11.7 11.9 14.6 19.8 13.6 24.4 10.5 19.2 27.3 20.2 16.5 14.1 19.9 18.9 20.4 4.8 37.7 8.7 39.7 17.7 27.3 44.7 25.7 50.0 3.6 47.6 58.6 39.0 3.5 29.0 21.3 36.6 11.3 58.6 29.4 14.1 11.7 17.1 13.9 34.5 33.0 23.4 65.9 41.2 9.7 5.6 13.8 7.2 12.1 67.8 17.5 33.3 11.7 31.3 8.7 27.5 77.6 44.4 54.6 41.1 56.6 49.3 43.0 47.9 91.4 44.2 37.1 39.9 13.1 56.4 55.4 226.4 68.3 60.3 15.6 17.7 16.9 16.4 15.1 16.5 17.3 17.2 18.4 17.4 16.6 18.6 33.2 0.0 11.0 3.3 30.5 11.5 14.8 11.1 5.2 3.8 23.8 23.4 4.2 31.5 15.3 12.9 0.0 15.0 73.4 12.1 21.5 45.2 32.6 11.6 4.7 20.1 15.6 11.1 3.0 43.4 9.4 12.3 9.2 12.0 31.8 13.0 17.5 9.0 44.9 1.7 3.1 18.0 28.5 47.4 45.1 19.8 9.3 45.4 16.0 7.5 47.7 30.5 53.5 5.0 8.2 24.8 22.7 15.8 22.5 14.3 22.3 29.3 17.6 6.0 19.7 13.0 22.0 19.6 22.1 23.2 18.9 9.3 33.5 7.4 16.9 14.1 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MKLN1 TWA2 ENSG00000128585 "Muskelin 1" Q9UL63 7 131110096-131496632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 455.1;Excitatory neurons: 336.5;Inhibitory neurons: 256.4;Oligodendrocyte precursor cells: 369.5;Oligodendrocytes: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022817, HPA041810" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA022817: AB_1853974, HPA041810: AB_2677686" "unprognostic (1.97e-1)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.03e-1)" "unprognostic (4.20e-2)" "unprognostic (1.44e-3)" "unprognostic (4.58e-2)" "unprognostic (1.94e-2)" "unprognostic (1.97e-1)" "unprognostic (2.43e-3)" "unprognostic (1.55e-1)" "unprognostic (9.18e-3)" "unprognostic (1.70e-1)" "unprognostic (4.13e-1)" "unprognostic (1.13e-2)" "unprognostic (2.32e-1)" 12.6 12.1 20.0 6.9 22.3 9.1 13.6 23.1 17.8 10.8 19.1 7.5 9.0 10.1 11.8 7.5 11.9 7.1 8.9 17.1 22.3 13.8 14.7 7.6 8.8 19.4 24.7 13.8 7.7 10.0 4.6 11.6 22.8 16.0 7.3 22.0 11.3 13.4 10.5 9.6 8.4 9.0 18.8 8.7 8.4 9.5 21.4 8.6 11.3 13.5 7.7 7.2 5.4 21.5 14.1 16.0 13.6 13.8 32.8 29.6 8.5 13.3 30.7 14.8 18.8 7.3 11.9 14.6 9.0 16.7 29.3 9.5 14.4 13.1 24.2 14.5 7.0 6.2 13.1 8.5 15.7 10.4 8.7 17.7 8.8 20.6 10.0 15.9 13.7 8.8 23.3 10.2 18.6 5.2 12.3 11.1 15.5 11.4 8.3 7.7 16.0 10.1 16.4 8.1 7.0 15.2 25.7 25.7 12.9 14.1 5.0 12.9 14.1 11.5 6.5 21.1 11.0 24.7 10.0 24.6 39.6 12.3 17.2 1.2 0.7 1.4 1.1 0.9 0.8 0.9 1.1 0.9 0.8 1.6 1.7 1.4 9.5 0.7 1.3 1.2 0.7 0.5 20.0 22.3 23.1 17.8 17.1 22.3 19.4 24.7 22.8 18.8 21.4 21.5 54.4 51.3 43.7 455.1 42.6 44.1 29.3 22.9 31.9 49.7 34.6 21.5 24.9 38.6 27.4 46.0 70.9 17.3 37.6 33.2 7.9 23.0 5.7 30.5 60.4 50.5 37.1 38.9 336.5 23.7 17.4 46.3 36.7 46.9 34.2 42.9 64.2 78.3 21.7 53.8 256.4 29.4 28.5 41.9 52.1 7.8 68.0 35.1 35.6 210.8 44.9 44.1 26.8 369.5 332.5 27.1 36.5 84.2 40.2 49.3 38.7 31.4 25.9 64.9 85.5 64.3 56.9 41.1 28.0 28.9 45.9 14.8 37.9 35.9 28.4 39.1 MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565674-23630075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1;retina: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.8;Cone photoreceptor cells: 25.0;Horizontal cells: 6.7;Oligodendrocyte precursor cells: 6.0;Oligodendrocytes: 9.0;Rod photoreceptor cells: 7.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "JURKAT: 26.3;K-562: 30.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: AB_10603873" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (4.26e-1)" "unprognostic (1.86e-3)" "unprognostic (1.04e-3)" "unprognostic (1.15e-2)" "unprognostic (6.27e-4)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.97e-3)" "unprognostic (2.86e-1)" "unprognostic (1.05e-4)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (8.91e-2)" "unprognostic (9.78e-2)" 0.3 0.1 4.5 0.4 7.7 1.8 0.5 4.8 6.7 0.1 2.4 0.5 0.2 0.4 1.6 3.4 3.1 0.1 0.1 5.2 5.1 0.3 0.1 0.2 0.7 7.0 6.1 0.2 0.4 0.0 1.1 3.3 7.0 0.3 0.1 8.9 3.1 0.2 0.8 0.4 0.3 0.1 4.0 0.6 0.2 2.4 6.6 2.4 0.2 0.8 0.8 0.2 0.2 14.1 8.5 2.9 6.1 5.6 0.0 0.0 13.0 0.9 0.0 4.3 4.5 14.7 0.0 0.1 0.1 0.0 11.8 12.5 2.4 0.0 2.7 0.1 0.5 15.3 17.0 0.9 0.4 18.6 10.2 0.6 0.0 5.8 0.0 2.8 0.0 26.3 30.6 12.9 3.5 0.0 20.3 7.3 0.0 9.6 12.1 10.7 2.5 7.5 0.0 0.1 1.6 4.4 0.0 7.7 0.1 0.2 4.2 5.2 0.1 13.5 9.9 0.9 9.6 16.8 24.5 8.6 7.9 0.1 0.1 0.6 0.2 0.1 0.6 0.0 0.3 0.2 0.2 0.4 0.0 0.2 0.6 2.3 0.4 0.1 0.1 0.3 0.1 0.3 4.5 7.7 4.8 6.7 5.2 5.1 7.0 6.1 7.0 4.0 6.6 14.1 0.0 0.0 0.0 0.7 0.1 0.5 1.2 0.0 0.0 13.8 0.3 0.0 0.7 0.0 0.1 0.0 25.0 0.8 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.6 0.5 0.0 0.1 1.8 1.0 0.1 3.4 0.0 6.0 9.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.2 7.4 0.0 0.7 1.6 2.6 0.9 1.8 0.0 0.5 0.2 0.1 0.0 0.4 MLF2 NTN4 ENSG00000089693 "Myeloid leukemia factor 2" Q15773 12 6747996-6767475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010811, HPA010859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA010811: AB_1079389, HPA010859: AB_1079388" "unprognostic (1.65e-1)" "unprognostic (6.55e-2)" "unprognostic (4.42e-1)" "unprognostic (9.88e-3)" "unprognostic (1.76e-1)" "unprognostic (4.19e-2)" "unprognostic (1.52e-1)" "unprognostic (4.15e-2)" "unprognostic (1.31e-1)" "unprognostic (9.11e-2)" "unprognostic (3.37e-1)" "unprognostic (6.23e-2)" "unprognostic (1.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.72e-1)" "unprognostic (8.44e-2)" "unprognostic (3.63e-1)" 121.0 199.0 214.6 67.9 225.7 123.8 109.8 206.5 243.7 119.8 215.4 161.8 106.3 148.5 85.2 168.6 120.6 68.1 181.8 234.6 219.0 163.3 298.7 107.0 66.2 208.0 205.8 116.3 111.0 158.2 145.1 79.4 205.8 142.7 74.1 78.2 131.6 96.3 192.8 144.6 117.8 93.0 205.4 101.5 135.9 97.6 211.1 78.3 114.1 129.2 71.2 135.2 117.5 223.6 222.0 354.3 179.1 294.4 159.3 157.9 283.1 216.6 230.6 318.8 286.9 353.8 195.5 163.1 55.0 265.5 228.1 173.5 220.1 295.3 220.0 274.9 239.3 115.3 174.0 200.7 176.0 128.9 143.0 151.7 240.8 255.2 209.8 257.4 140.7 152.0 152.5 61.8 247.8 320.7 165.7 197.9 554.2 236.1 141.2 102.5 160.2 134.0 310.8 247.7 111.2 224.8 188.8 303.6 203.4 385.8 89.8 186.4 133.7 191.4 279.3 213.5 299.9 80.9 98.2 208.9 259.0 102.2 231.2 259.6 120.3 461.0 82.0 109.9 80.9 85.6 63.7 78.3 134.0 97.6 66.2 75.3 528.0 76.6 129.2 231.6 69.7 115.3 214.6 225.7 206.5 243.7 234.6 219.0 208.0 205.8 205.8 205.4 211.1 223.6 106.3 38.5 30.9 19.2 77.9 136.5 149.3 230.2 261.2 110.2 157.7 156.3 71.9 92.9 108.7 110.3 41.7 264.3 92.4 120.6 279.7 169.9 12.1 64.6 70.7 86.4 100.7 74.9 36.2 125.9 213.7 100.6 91.7 74.9 84.9 84.1 71.0 168.6 147.7 80.8 32.7 138.6 197.4 57.8 70.6 13.3 114.0 78.9 103.2 13.1 138.9 142.7 39.1 19.1 23.5 153.8 124.7 107.2 108.2 202.6 219.6 324.7 58.6 63.5 52.6 77.1 131.8 96.6 80.8 193.1 125.6 427.6 70.2 138.3 145.0 174.6 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MLST8 "GbetaL, GBL, Lst8, Pop3" ENSG00000167965 "MTOR associated protein, LST8 homolog" Q9BVC4 16 2204248-2209453 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019935, HPA041841" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Golgi apparatus, Cell Junctions" "CAB019935: AB_561447, HPA041841: AB_2677701" "unprognostic (2.19e-1)" "unprognostic (7.68e-2)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (3.35e-3)" "unprognostic (1.74e-1)" "unprognostic (8.17e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" "unprognostic (5.70e-3)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.60e-4)" "unprognostic (8.74e-2)" "unprognostic (1.20e-1)" "unprognostic (2.29e-1)" "unprognostic (5.48e-2)" 16.7 29.4 31.5 9.8 31.8 13.3 17.1 31.4 51.1 16.0 25.5 17.3 12.5 15.5 5.6 24.8 14.6 9.1 25.0 32.4 29.9 26.0 31.3 13.3 10.5 32.0 31.0 19.4 35.8 13.3 19.8 11.1 32.4 20.5 4.6 5.7 19.7 8.0 39.4 22.2 15.6 4.5 29.4 16.5 22.3 33.6 32.5 9.7 22.4 21.8 5.2 16.7 15.5 34.1 20.5 61.9 23.1 60.5 29.6 20.8 38.2 17.9 20.4 26.7 22.9 83.4 29.5 51.3 40.6 20.1 12.7 25.8 23.1 51.4 3.1 39.4 113.4 36.0 61.0 51.7 44.7 57.3 49.7 29.7 34.8 31.7 41.8 22.6 28.6 74.1 54.9 35.9 14.8 89.4 55.5 74.9 47.3 18.1 57.4 55.6 23.4 93.8 20.7 13.4 73.5 40.1 26.6 62.1 46.3 8.7 38.6 54.2 22.4 33.5 38.9 27.3 23.7 43.0 26.4 57.8 17.6 47.5 29.9 0.0 25.0 4.2 14.1 29.9 11.8 14.4 13.1 15.2 24.6 12.5 15.0 15.1 2.8 14.6 30.1 13.3 13.1 20.7 31.5 31.8 31.4 51.1 32.4 29.9 32.0 31.0 32.4 29.4 32.5 34.1 11.5 6.4 16.0 10.4 24.6 14.7 16.2 29.6 21.6 31.5 24.7 29.8 3.3 15.7 16.2 16.5 20.9 63.2 13.0 44.6 35.2 34.4 48.7 9.6 13.1 16.8 28.8 26.9 8.9 42.6 50.4 19.2 42.8 11.2 8.2 26.8 20.3 16.7 46.9 30.3 8.4 37.9 22.4 19.1 14.6 105.4 14.9 18.4 17.8 1.0 28.0 29.4 19.6 5.5 5.9 28.6 37.9 15.1 34.1 17.9 43.2 36.3 11.1 30.6 19.7 11.6 16.5 34.7 28.2 29.4 15.5 52.7 15.4 26.8 49.3 17.4 MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: AB_2681940, HPA064438: AB_2685265" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.21e-3)" "unprognostic (3.88e-1)" "unprognostic (2.46e-2)" "unprognostic (8.55e-3)" "unprognostic (2.49e-1)" "unprognostic (4.87e-2)" "unprognostic (8.66e-2)" "unprognostic (9.66e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-2)" "unprognostic (7.43e-2)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.25e-1)" 31.3 28.0 15.8 21.7 16.4 16.4 26.2 16.6 18.0 19.3 19.1 38.5 47.5 15.7 16.6 29.1 17.2 20.3 55.5 16.2 16.9 28.7 51.5 27.9 27.5 16.9 15.9 14.8 32.7 19.6 18.8 21.5 16.8 18.2 38.8 9.3 24.7 18.1 74.4 25.6 42.2 20.3 16.7 24.1 35.4 8.1 16.8 30.1 24.8 86.4 29.4 27.9 20.8 17.2 36.8 41.5 32.1 33.1 48.0 55.3 22.0 53.5 47.5 57.1 51.4 38.0 37.5 43.6 36.8 46.4 51.6 54.4 59.4 34.8 50.0 35.2 55.5 45.4 27.2 43.1 56.3 61.6 63.4 47.9 38.4 45.6 41.8 38.9 42.9 52.2 50.7 38.3 66.2 49.3 87.0 31.3 22.9 90.9 37.3 39.2 66.1 47.5 46.8 44.7 49.9 24.6 23.9 31.2 61.8 42.5 63.3 72.1 30.2 50.7 32.5 55.7 80.8 38.7 47.2 41.2 56.5 39.2 60.8 43.3 64.0 91.4 34.2 80.1 37.6 35.2 35.0 34.6 66.5 30.2 30.5 31.1 82.7 33.7 90.9 35.7 48.0 68.3 15.8 16.4 16.6 18.0 16.2 16.9 16.9 15.9 16.8 16.7 16.8 17.2 31.6 67.3 69.8 9.4 35.6 41.9 28.1 41.5 33.0 29.4 39.8 30.4 24.1 40.0 47.2 27.6 25.0 37.8 35.8 97.7 60.7 48.9 19.1 30.5 29.1 28.2 25.8 42.7 8.0 68.9 49.5 26.0 55.5 26.3 46.7 18.7 27.8 49.7 68.6 25.2 8.1 46.9 30.5 63.4 62.3 24.5 35.1 59.5 32.0 7.5 58.3 13.1 51.5 5.5 7.1 77.5 86.4 31.2 61.8 24.4 132.3 62.1 30.4 31.7 52.6 22.9 31.4 9.3 41.2 45.2 49.9 44.1 38.3 48.0 54.2 36.4 MMACHC "cblC, DKFZP564I122" ENSG00000132763 "Metabolism of cobalamin associated C" Q9Y4U1 1 45500300-45513382 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 17.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027394, HPA027399, HPA027402" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA027394: AB_10601669, HPA027399: AB_10601987, HPA027402: AB_2672255" "unprognostic (3.34e-1)" "unprognostic (1.63e-1)" "unprognostic (7.03e-3)" "unprognostic (3.14e-2)" "unprognostic (4.05e-1)" "unprognostic (1.16e-2)" "unprognostic (9.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-2)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.61e-3)" "unprognostic (2.08e-3)" "unprognostic (8.83e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" 2.0 3.1 3.3 1.7 5.3 1.2 3.5 5.1 4.2 2.9 2.3 3.7 3.3 1.7 3.0 2.8 3.5 1.3 6.9 3.4 5.1 3.5 17.4 1.2 1.8 4.1 5.6 3.5 2.9 5.5 1.3 1.5 3.9 2.0 4.4 2.1 5.0 2.4 10.8 2.0 2.4 2.3 3.5 1.6 2.3 4.3 5.6 2.2 2.3 6.6 2.0 1.7 1.5 6.0 7.7 3.9 6.6 10.0 6.1 3.7 8.1 5.9 3.9 10.5 9.4 8.3 4.7 12.0 7.4 4.9 2.0 6.2 12.3 14.0 9.6 3.3 11.4 9.4 6.5 9.2 5.8 13.5 3.3 5.3 7.8 11.6 12.6 3.7 5.1 12.5 10.8 6.7 8.1 8.2 9.1 4.3 10.9 8.8 8.9 11.1 2.7 13.2 6.2 6.0 10.5 5.4 8.8 14.5 19.3 4.9 8.3 4.6 2.3 7.3 9.9 8.3 3.3 9.9 8.5 6.9 5.3 6.4 6.9 2.3 0.5 0.5 0.5 0.8 0.8 0.7 0.7 0.4 0.6 0.6 1.3 0.6 0.9 0.8 2.7 1.3 0.4 0.4 3.3 5.3 5.1 4.2 3.4 5.1 4.1 5.6 3.9 3.5 5.6 6.0 1.1 3.2 5.5 1.6 2.1 0.1 1.8 0.8 5.7 1.3 2.7 1.5 9.8 4.3 2.2 1.8 0.0 3.7 0.6 2.8 5.9 1.3 1.0 3.6 4.8 1.5 4.2 4.8 2.6 1.4 4.3 3.6 7.1 3.2 2.5 2.9 2.5 22.9 3.3 3.3 2.7 3.2 2.0 3.2 0.9 1.2 1.8 2.7 0.0 0.0 0.6 1.4 3.1 1.5 5.3 1.8 2.3 1.5 10.4 1.7 2.0 4.6 1.2 5.2 0.0 5.0 2.4 7.4 2.1 11.5 0.1 2.7 2.4 3.9 5.8 1.8 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Distal enterocytes: 109.3;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 93.6;Hep G2: 51.1;OE19: 44.6;SK-BR-3: 47.3;WM-115: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" 11.9 3.8 8.9 4.4 6.0 0.4 7.6 7.3 11.2 5.7 5.8 28.0 40.2 3.5 1.1 4.6 6.1 14.3 41.2 6.9 8.7 14.9 50.1 9.9 2.1 15.8 10.6 1.1 18.5 12.7 8.8 28.4 16.8 4.4 14.3 1.5 8.4 9.5 7.0 4.3 33.0 3.7 5.8 9.3 29.6 34.9 18.7 1.0 46.7 5.6 1.3 5.1 2.8 8.6 15.3 11.4 5.8 30.4 6.0 0.3 93.6 1.4 0.8 5.4 1.2 9.1 38.3 0.2 17.7 1.6 4.2 21.0 5.1 4.4 1.6 0.1 10.0 0.1 4.9 51.1 7.7 0.3 19.5 3.1 7.8 0.9 2.3 8.4 3.7 8.5 12.9 0.1 1.8 7.6 0.7 2.6 17.2 44.6 3.2 7.6 0.7 8.3 16.6 5.4 1.6 10.4 20.0 47.3 9.5 13.2 5.2 8.2 3.4 0.4 9.1 3.5 1.3 0.2 0.1 0.3 1.9 2.3 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.9 6.0 7.3 11.2 6.9 8.7 15.8 10.6 16.8 5.8 18.7 8.6 14.3 19.2 14.4 9.1 0.7 2.5 1.0 4.9 2.8 3.4 5.0 3.0 24.7 55.8 12.6 18.4 16.7 48.2 1.6 109.3 1.9 35.7 5.0 3.6 1.1 17.2 11.4 2.7 1.4 12.0 49.2 4.5 35.2 6.4 0.0 18.6 13.6 39.2 12.9 1.7 1.2 33.3 10.2 3.0 0.3 6.9 0.9 0.9 1.8 1.0 0.0 2.1 0.0 4.5 1.4 13.3 38.5 3.4 0.3 1.3 67.3 7.3 6.0 1.9 0.0 0.7 2.4 0.9 4.6 3.3 2.3 48.4 0.7 23.2 45.0 1.7 MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 219.1;Kupffer cells: 408.5;Langerhans cells: 241.7;Macrophages: 412.0;monocytes: 1118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Group enriched" "Detected in some" 14 "NB-4: 151.8;THP-1: 282.7;U-937: 185.5" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" 24.2 14.9 2.7 82.4 2.8 292.9 6.0 2.9 4.4 6.3 3.2 6.7 3.7 4.0 1.4 7.4 5.7 26.6 4.3 2.6 3.1 3.6 11.5 47.3 15.6 5.2 4.3 2.2 4.8 3.7 1.6 20.4 4.3 3.8 7.7 12.1 5.7 3.5 3.8 5.1 7.7 20.7 5.1 107.8 4.5 5.1 4.2 14.4 3.8 19.0 14.5 23.4 1.8 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 14.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 282.7 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 185.5 0.0 155.4 1354.4 243.8 2.6 534.3 3.7 33.5 1.6 1.9 616.5 15.3 1.6 1.4 6012.8 2.8 270.6 9.6 1.5 1099.5 2.7 2.8 2.9 4.4 2.6 3.1 5.2 4.3 4.3 5.1 4.2 5.4 2.6 35.3 56.0 0.0 34.7 2.4 0.0 0.0 0.0 1.2 1.1 3.4 0.9 5.7 9.3 0.0 0.0 0.9 5.9 0.0 0.0 0.0 0.4 0.1 0.1 5.0 0.0 22.3 0.0 0.4 1.3 6.5 0.5 0.1 44.1 0.0 3.9 2.2 219.1 0.0 0.1 0.0 0.0 408.5 241.7 3.3 1.2 412.0 1.8 33.7 1118.9 136.1 26.8 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 1.7 8.0 4.8 13.1 1.5 8.2 0.9 0.3 0.4 2.3 1.0 11.7 0.0 0.0 0.1 MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 7.2;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 6.6;Enteroendocrine cells: 25.1;Intestinal goblet cells: 19.7;Paneth cells: 7.0;Proximal enterocytes: 7.3;Undifferentiated cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 17.2;BEWO: 12.7;EFO-21: 16.2;HEK 293: 13.2;RPMI-8226: 37.6;SCLC-21H: 19.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 39 "spinal cord: 3.9" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "HPA071717: AB_2686437" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.87e-2)" "unprognostic (3.72e-3)" "unprognostic (8.85e-2)" "unprognostic (1.08e-2)" "unprognostic (2.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.06e-2)" "unprognostic (8.62e-4)" "unprognostic (1.00e-2)" "unprognostic (3.35e-2)" "unprognostic (2.23e-5)" "unprognostic (1.67e-3)" "unprognostic (5.80e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.3 0.6 0.0 0.0 3.7 7.2 0.0 0.0 0.2 0.0 0.8 0.0 0.5 0.2 0.1 0.0 0.0 0.0 1.3 0.3 0.0 16.3 0.0 2.6 0.0 0.9 0.3 3.0 0.0 1.1 0.0 0.0 0.1 6.1 0.0 0.8 0.0 2.2 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.4 5.8 0.0 17.2 0.0 0.0 12.7 0.0 0.0 0.1 0.0 7.6 2.5 1.4 16.2 0.0 0.5 0.3 3.0 2.3 1.3 2.2 13.2 0.0 1.5 3.6 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 6.1 5.7 2.9 0.0 10.1 0.9 0.2 0.0 1.7 1.1 0.0 2.5 37.6 6.5 0.6 19.3 0.0 2.5 2.2 0.4 0.1 5.4 4.4 0.0 0.0 0.0 0.0 0.0 5.3 2.9 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.6 0.5 0.2 1.3 0.3 0.9 0.8 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 4.4 1.3 0.1 0.0 0.1 25.1 0.0 0.0 3.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 19.7 0.0 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 3.1 7.0 0.0 0.4 0.0 7.3 0.1 0.0 0.0 0.0 0.0 0.2 1.8 0.8 0.0 0.0 0.0 0.2 0.0 13.6 0.0 MOB1A "C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B" ENSG00000114978 "MOB kinase activator 1A" Q9H8S9 2 74152528-74178898 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047088, HPA071690" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA047088: AB_2679927, HPA071690: AB_2686432" "unprognostic (5.32e-2)" "unprognostic (2.45e-1)" "unprognostic (5.38e-2)" "unprognostic (2.62e-1)" "unprognostic (2.19e-1)" "unprognostic (8.19e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (9.36e-2)" "unprognostic (3.91e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-3)" "unprognostic (1.04e-1)" "unprognostic (2.20e-3)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" "unprognostic (5.11e-3)" 36.6 24.7 12.6 64.2 11.8 90.5 31.4 12.9 13.5 36.4 18.6 41.0 42.3 35.0 25.5 40.2 33.2 35.5 25.3 11.4 15.6 48.1 30.7 38.9 91.9 15.8 13.6 31.9 16.0 28.6 9.1 35.8 16.7 30.3 42.7 10.2 19.5 29.4 13.2 38.9 41.7 40.5 15.8 61.1 34.2 19.8 12.8 56.1 33.6 19.4 93.1 46.6 26.0 17.9 78.2 43.9 53.9 58.5 86.9 94.0 63.5 61.3 82.0 78.1 76.6 60.2 55.4 159.0 51.3 77.4 58.2 63.7 69.6 70.2 117.7 113.0 41.5 143.7 28.0 64.3 69.1 126.1 222.1 80.2 67.1 62.6 52.5 58.6 83.3 60.4 62.5 57.2 76.8 42.1 159.4 106.9 50.3 66.4 35.6 108.2 185.2 85.2 67.3 96.1 27.3 35.6 87.1 63.6 56.4 40.4 51.0 59.1 79.6 100.9 53.0 71.4 98.7 42.2 40.5 119.5 68.0 105.3 55.3 103.7 65.3 91.5 37.3 106.1 40.3 57.8 33.3 40.3 60.5 46.1 30.2 36.4 65.6 56.4 126.0 42.1 37.2 79.7 12.6 11.8 12.9 13.5 11.4 15.6 15.8 13.6 16.7 15.8 12.8 17.9 82.6 51.3 58.0 3.9 173.0 136.9 96.5 107.4 60.9 13.3 66.8 45.1 40.0 35.8 79.5 82.8 6.2 63.8 170.1 114.1 92.0 60.9 11.1 88.3 91.3 73.1 37.7 48.8 7.4 52.6 101.9 67.2 55.0 102.2 110.4 58.5 61.1 43.0 169.5 26.9 7.9 67.4 65.1 196.6 246.9 11.8 62.4 226.1 67.6 14.0 350.8 25.2 117.4 6.0 10.1 83.4 85.7 68.4 106.4 127.8 80.4 170.2 116.6 14.5 72.3 60.6 75.3 99.5 44.6 86.6 132.0 66.4 124.4 79.3 74.0 155.3 MOB1B "MOB4A, MOBKL1A" ENSG00000173542 "MOB kinase activator 1B" Q7L9L4 4 70902326-71022449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047088, HPA071690" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoplasm, Nucleoli" "HPA047088: AB_2679927, HPA071690: AB_2686432" "unprognostic (1.05e-1)" "unprognostic (1.48e-2)" "unprognostic (1.84e-1)" "unprognostic (2.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (2.94e-1)" "unprognostic (1.36e-1)" "unprognostic (3.45e-1)" "unprognostic (1.42e-2)" "unprognostic (1.07e-1)" "unprognostic (1.09e-3)" "unprognostic (2.70e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-3)" 7.3 7.5 9.4 9.6 12.0 30.0 8.4 5.4 13.0 7.5 19.4 5.8 4.8 7.8 5.0 7.5 8.9 6.9 8.5 19.1 13.5 22.5 6.5 9.6 11.3 9.7 11.3 7.8 8.6 12.5 4.0 8.8 10.0 9.6 6.3 4.9 8.5 5.4 6.1 8.8 5.4 7.7 12.9 8.8 8.1 6.0 8.1 20.0 11.0 6.3 10.3 6.9 5.3 15.8 8.2 6.6 24.2 19.9 12.9 16.2 20.2 24.2 13.2 13.3 11.5 8.8 15.3 45.6 11.5 21.6 9.1 5.7 15.2 20.3 31.9 25.1 5.5 71.5 7.4 6.8 12.9 15.6 13.8 13.5 10.9 14.9 12.0 14.8 15.9 23.4 45.0 14.5 21.3 8.9 49.2 9.7 8.0 5.3 8.5 15.6 23.5 6.1 22.1 14.1 8.4 16.5 10.6 4.7 32.9 12.9 10.9 10.0 19.3 36.6 18.9 16.8 10.0 9.2 3.4 19.1 12.8 11.5 17.2 0.3 1.2 1.1 0.5 0.6 0.4 0.1 0.2 0.2 1.7 0.2 0.3 0.2 0.1 0.2 0.4 2.1 0.6 0.5 9.4 12.0 5.4 13.0 19.1 13.5 9.7 11.3 10.0 12.9 8.1 15.8 11.1 25.6 19.1 42.4 8.9 17.8 6.0 6.1 18.8 3.3 13.7 8.8 17.4 5.7 10.2 44.1 18.8 5.6 31.5 2.6 9.8 5.4 0.8 27.2 16.0 12.8 37.8 99.1 38.4 4.6 5.6 12.1 7.1 25.6 10.8 24.5 9.7 7.1 11.2 6.7 36.5 8.9 4.1 29.2 39.7 1.6 4.4 33.5 10.6 65.6 45.6 6.0 8.2 41.7 12.1 9.4 2.1 8.6 6.9 11.5 1.4 17.1 16.9 4.5 26.3 8.7 23.0 6.4 9.0 15.1 17.0 5.7 10.3 23.4 6.6 9.4 MOB2 HCCA2 ENSG00000182208 "MOB kinase activator 2" Q70IA6 11 1469457-1501247 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046313 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Nucleoplasm, Cytosol" "HPA046313: AB_10959882" "unprognostic (5.02e-1)" "unprognostic (5.71e-2)" "unprognostic (6.24e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.30e-2)" "unprognostic (1.06e-3)" "unprognostic (3.06e-2)" "unprognostic (1.77e-1)" "unprognostic (2.80e-2)" "unprognostic (5.30e-2)" "unprognostic (2.87e-1)" "prognostic favorable (2.02e-4)" "unprognostic (2.67e-1)" "unprognostic (8.56e-2)" "unprognostic (9.78e-2)" "unprognostic (1.15e-1)" 32.3 19.6 34.7 19.2 36.3 24.2 28.3 37.8 39.7 27.4 36.2 61.1 18.0 30.7 36.5 51.9 34.4 27.8 43.5 35.3 36.5 18.6 20.0 24.7 26.8 36.1 36.8 28.1 32.8 34.9 11.2 25.7 36.5 32.5 34.8 14.6 35.2 42.3 50.9 50.0 28.6 49.0 36.1 25.1 27.9 14.2 37.1 34.1 24.2 70.4 27.0 39.9 31.6 37.8 29.3 31.2 18.3 15.7 44.2 30.8 17.1 22.5 30.9 40.4 31.8 20.1 39.0 20.9 16.7 50.6 26.0 34.8 28.1 48.6 24.3 28.8 44.3 16.0 11.7 26.2 30.2 21.2 24.2 25.1 57.9 21.9 25.3 32.7 43.6 27.0 26.3 21.2 20.7 20.6 27.4 37.7 23.0 54.3 29.4 19.9 19.0 22.2 34.4 26.9 34.6 37.3 27.3 34.0 27.9 23.0 15.9 21.3 37.7 25.6 13.1 8.3 14.5 21.6 22.3 21.8 17.9 20.3 19.8 9.7 8.7 11.9 16.2 9.2 13.6 8.1 14.1 13.7 10.6 11.0 11.6 10.2 7.1 12.1 13.4 7.5 15.3 10.6 34.7 36.3 37.8 39.7 35.3 36.5 36.1 36.8 36.5 36.1 37.1 37.8 84.8 6.4 10.0 6.5 20.2 82.2 30.1 39.4 12.0 18.4 27.8 33.3 14.8 12.8 18.4 7.3 12.5 31.1 64.5 58.6 27.4 33.5 24.3 18.9 17.7 58.2 20.9 36.2 15.2 38.5 31.0 23.3 16.8 29.2 24.8 20.3 33.9 9.0 26.4 43.7 10.9 32.8 32.6 18.2 39.3 12.1 23.9 28.1 56.9 11.2 29.4 21.5 81.4 6.6 14.8 39.6 63.2 51.1 17.0 48.6 54.3 23.9 12.9 21.4 85.5 20.8 68.3 29.8 41.1 13.7 82.0 59.4 36.4 20.2 27.7 37.6 MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 573.2;Proximal tubular cells: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favorable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 48.7 79.4 79.1 24.9 84.9 9.1 42.1 80.3 107.6 34.7 74.4 41.9 40.8 30.0 45.9 35.2 26.5 31.3 87.0 84.3 86.3 114.8 126.2 28.2 26.1 79.2 80.5 43.5 42.4 89.6 30.5 35.9 82.4 36.8 32.3 59.3 48.9 44.9 109.3 16.6 40.2 34.4 85.6 23.6 37.2 26.0 88.0 28.3 55.4 111.8 25.2 30.8 24.6 87.4 79.4 62.7 42.9 109.9 85.0 83.2 51.6 99.5 91.9 74.4 89.8 79.7 56.5 76.7 143.5 69.9 127.1 45.0 91.7 96.7 117.2 19.6 84.8 61.7 58.2 75.9 94.4 65.0 43.0 65.1 41.7 91.7 83.5 81.0 85.1 101.4 58.7 44.2 129.5 115.5 72.7 31.8 37.0 34.2 130.1 36.0 93.0 67.0 144.1 56.6 29.4 33.7 69.4 57.3 72.9 56.9 107.2 15.4 55.6 76.9 81.0 69.1 120.5 49.4 84.8 91.5 106.7 16.8 125.1 14.5 21.8 15.6 36.9 26.9 46.2 37.5 42.7 42.8 29.8 40.5 55.3 49.2 3.8 43.5 25.4 27.8 44.9 28.9 79.1 84.9 80.3 107.6 84.3 86.3 79.2 80.5 82.4 85.6 88.0 87.4 51.7 54.5 29.7 14.4 23.5 13.4 40.1 48.5 19.9 30.2 55.7 50.5 122.9 62.9 37.9 69.9 27.1 95.4 19.4 18.2 573.2 43.7 7.3 22.6 29.0 37.6 26.4 18.7 19.1 43.7 37.3 55.7 19.9 26.8 10.1 38.8 26.0 132.6 41.3 6.7 18.4 22.7 44.7 31.2 20.1 14.6 50.7 28.7 23.2 6.5 12.2 67.5 29.9 4.5 11.9 22.1 18.2 68.8 26.7 34.5 65.7 281.7 32.9 21.7 32.9 73.8 49.4 46.7 62.9 37.5 15.6 32.3 25.8 64.2 30.9 34.5 MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130632-71150101 "Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: AB_2674436, HPA035060: AB_10601875, HPA049907: AB_2680947" "unprognostic (3.20e-3)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (6.41e-3)" "unprognostic (6.13e-2)" "unprognostic (3.50e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (3.89e-7)" "unprognostic (1.24e-1)" "unprognostic (2.91e-1)" "unprognostic (2.47e-1)" "unprognostic (2.23e-2)" 22.6 18.4 15.2 20.4 16.4 26.5 25.0 17.7 21.4 19.9 15.4 17.6 17.7 22.1 27.5 28.6 16.6 18.4 23.2 15.3 17.7 17.8 30.8 16.9 25.2 17.1 17.0 25.9 19.7 22.9 15.8 20.3 17.0 24.6 19.1 15.1 21.0 16.7 33.1 26.7 15.5 16.8 15.6 19.6 17.8 15.4 16.3 22.5 21.7 24.0 27.5 23.8 18.1 17.6 45.8 33.7 42.7 51.3 39.1 36.7 58.3 49.8 39.6 40.6 29.7 60.7 32.9 64.3 30.5 35.3 31.0 41.1 54.8 35.3 54.1 44.7 43.2 77.3 26.3 139.1 34.1 101.0 58.2 32.0 44.4 33.4 44.4 27.4 34.8 39.1 113.5 49.1 41.0 49.1 81.6 101.5 71.0 63.5 38.1 66.6 66.7 75.4 33.1 49.0 51.8 40.0 33.6 75.0 49.9 36.1 38.2 44.5 36.0 47.2 51.1 45.3 64.0 41.0 50.6 104.1 40.5 82.8 49.1 17.6 12.4 9.8 15.2 17.8 20.2 18.0 19.6 18.8 15.3 15.0 21.4 19.2 1.9 17.1 26.1 16.3 18.3 11.3 15.2 16.4 17.7 21.4 15.3 17.7 17.1 17.0 17.0 15.6 16.3 17.6 38.6 35.3 55.5 8.1 36.8 33.4 42.7 37.8 30.7 37.2 26.0 36.8 44.5 30.0 53.0 18.4 4.2 50.5 47.7 17.9 25.4 47.8 6.0 40.4 52.4 40.4 18.0 26.9 9.8 41.8 48.1 43.2 19.9 65.4 48.1 31.2 21.8 33.2 27.2 18.5 11.4 21.6 26.4 17.7 20.8 6.3 48.7 19.0 12.4 15.0 39.2 25.5 47.4 12.1 15.9 33.1 15.0 43.6 25.6 40.6 14.2 22.7 29.2 53.2 39.5 62.2 49.1 70.2 84.5 35.6 33.5 32.4 39.9 42.8 28.2 31.9 MPHOSPH8 "HSMPP8, mpp8" ENSG00000196199 "M-phase phosphoprotein 8" Q99549 13 19633659-19673441 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039701, HPA040035" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA039701: AB_10805484, HPA040035: AB_10794207" "unprognostic (4.22e-1)" "unprognostic (5.58e-2)" "unprognostic (2.66e-1)" "unprognostic (4.01e-3)" "unprognostic (3.05e-2)" "unprognostic (1.86e-1)" "unprognostic (2.81e-3)" "unprognostic (4.90e-2)" "unprognostic (4.55e-2)" "unprognostic (1.59e-1)" "unprognostic (3.52e-3)" "unprognostic (3.40e-2)" "unprognostic (6.49e-2)" "unprognostic (3.86e-2)" "unprognostic (4.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.02e-1)" 29.0 32.5 32.4 30.0 31.9 27.9 28.7 36.5 48.7 38.6 31.1 39.7 22.5 36.1 31.6 23.3 34.0 23.4 36.1 31.6 40.2 22.9 21.1 28.7 39.2 31.8 35.7 51.4 28.2 26.3 31.6 25.4 31.5 31.2 24.4 36.9 32.3 31.2 23.4 33.6 33.3 26.6 26.8 39.9 28.3 21.5 33.6 23.2 32.9 18.5 26.4 32.3 31.7 36.5 26.0 16.4 23.9 39.0 30.3 38.2 42.2 38.2 27.5 23.6 20.1 25.1 44.5 40.8 29.7 23.1 36.6 42.2 44.4 26.7 30.2 51.1 22.7 65.7 27.8 30.8 27.0 47.8 51.4 22.8 33.8 18.6 26.1 35.8 31.6 32.5 32.5 25.5 22.2 25.1 36.8 39.9 23.4 48.0 18.1 29.3 55.2 32.6 40.7 19.8 32.7 20.0 35.7 32.3 35.3 39.8 19.7 39.1 37.3 18.1 16.4 34.8 19.6 17.2 19.2 40.1 13.8 43.4 28.7 133.6 23.4 42.5 31.5 18.2 28.1 64.3 35.6 31.1 11.4 54.1 42.5 34.8 69.2 30.4 27.8 35.8 30.9 9.9 32.4 31.9 36.5 48.7 31.6 40.2 31.8 35.7 31.5 26.8 33.6 36.5 117.3 93.0 110.6 42.1 129.7 69.0 102.1 99.0 97.3 201.0 74.8 95.0 94.4 110.1 92.2 103.0 83.4 151.1 132.0 95.1 49.0 57.6 84.3 82.3 129.2 109.0 58.8 78.9 94.7 54.6 83.7 118.8 62.7 118.8 144.2 101.0 133.2 81.3 72.9 210.3 89.4 113.2 67.1 74.5 55.5 37.9 179.3 71.4 67.6 51.5 99.8 114.9 166.9 56.3 78.7 48.2 99.7 157.2 118.5 80.8 100.5 61.6 66.6 219.0 177.5 111.5 118.5 211.0 203.7 57.9 74.0 58.7 142.7 105.3 86.8 65.3 MPHOSPH9 MPP9 ENSG00000051825 "M-phase phosphoprotein 9" Q99550 12 123152320-123244014 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 87.7;Inhibitory neurons: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037485 Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centrosome" "HPA037485: AB_10672792" "unprognostic (2.98e-2)" "unprognostic (5.00e-1)" "unprognostic (4.36e-3)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.81e-1)" "unprognostic (5.81e-3)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (1.88e-1)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (6.53e-3)" "unprognostic (1.31e-2)" "unprognostic (2.75e-1)" "unprognostic (5.14e-3)" "unprognostic (1.17e-1)" 4.6 5.4 13.7 8.0 15.2 26.2 5.0 21.6 19.8 4.7 18.9 6.1 6.8 5.3 11.1 3.1 5.3 3.6 5.6 14.3 13.2 6.2 9.6 3.9 12.1 13.8 13.7 4.5 4.0 8.9 4.4 5.2 13.9 4.6 6.8 21.3 5.5 4.4 6.8 5.0 5.2 5.2 13.4 8.1 5.1 12.4 14.4 32.8 5.2 7.8 10.3 4.2 1.9 16.0 15.0 15.9 23.9 28.0 10.7 10.1 9.1 15.7 7.8 18.7 15.2 15.1 7.2 29.6 10.6 10.1 15.7 10.2 30.3 11.1 26.0 17.6 20.7 30.5 17.9 15.0 6.6 27.0 24.6 10.5 4.7 18.2 16.1 15.6 19.5 40.1 21.4 12.7 17.3 12.9 32.6 44.6 17.1 9.4 17.2 27.6 24.9 19.1 14.7 14.8 31.4 15.0 23.7 9.3 15.4 22.4 17.5 21.2 11.1 15.3 21.5 17.5 22.1 19.0 33.8 24.4 12.2 26.4 32.4 11.5 3.7 5.4 10.1 3.7 7.2 6.5 8.4 9.5 3.7 6.0 11.6 12.0 0.8 10.1 3.3 5.3 7.8 2.8 13.7 15.2 21.6 19.8 14.3 13.2 13.8 13.7 13.9 13.4 14.4 16.0 7.3 9.6 9.5 50.3 15.6 4.5 4.5 5.7 8.6 43.5 5.8 5.2 16.3 10.0 7.2 7.3 114.7 12.2 25.3 2.8 5.9 4.8 57.9 21.2 12.4 8.5 14.3 33.6 87.7 1.8 7.1 10.6 5.1 6.5 2.5 23.6 7.9 31.1 8.6 53.8 84.7 5.6 6.1 15.3 7.4 73.3 7.2 10.4 3.6 24.4 17.0 14.7 32.0 46.3 48.1 1.8 1.6 11.3 21.4 3.0 4.3 11.0 14.9 65.9 0.0 11.6 7.2 31.7 20.4 8.4 2.3 1.6 26.8 17.2 9.8 2.7 MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;skin 1: 8.3" "Cell type enriched" "Detected in single" 14 "granulocytes: 10.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 14 "HEL: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 330000 "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" 0.5 0.0 0.0 0.1 0.0 1.1 0.4 0.1 0.2 1.0 0.1 0.3 0.1 0.4 0.0 1.6 0.5 0.2 0.8 0.1 0.1 0.1 0.3 3.5 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.2 8.3 0.4 0.0 0.0 4.8 0.3 2.3 0.1 0.0 0.5 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.8 0.0 2.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 MPLKIP "C7orf11, ORF20, TTDN1" ENSG00000168303 "M-phase specific PLK1 interacting protein" Q8TAP9 7 40126027-40134622 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058457, HPA065463" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Golgi apparatus, Vesicles" "HPA058457: AB_2683724, HPA065463: AB_2685493" "unprognostic (5.59e-2)" "unprognostic (1.74e-1)" "unprognostic (9.40e-2)" "unprognostic (2.39e-2)" "unprognostic (5.55e-2)" "unprognostic (1.34e-3)" "unprognostic (2.73e-1)" "unprognostic (3.40e-2)" "unprognostic (3.94e-2)" "unprognostic (1.65e-1)" "unprognostic (3.16e-3)" "unprognostic (8.89e-2)" "unprognostic (1.61e-2)" "unprognostic (8.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-2)" "unprognostic (6.08e-2)" 2.9 3.8 2.6 2.0 2.6 2.4 2.8 4.7 3.0 2.8 3.0 2.8 2.2 2.6 2.0 3.1 2.5 1.2 2.1 2.6 2.3 4.2 8.0 2.1 2.6 2.4 2.3 2.8 2.9 2.5 3.0 1.8 2.6 2.5 1.8 3.1 2.7 1.5 2.4 3.0 2.6 1.1 2.0 3.1 2.4 2.3 2.5 3.3 3.0 1.4 2.0 2.5 2.7 4.0 8.2 2.5 4.8 6.6 4.3 4.9 4.9 3.1 3.3 4.4 4.3 3.1 4.0 6.8 4.2 3.0 8.7 10.3 3.0 5.3 5.6 5.2 9.2 5.4 3.7 6.9 4.9 6.7 5.2 4.8 6.7 3.4 4.1 4.5 5.1 7.5 13.1 5.5 4.4 4.1 6.8 20.4 6.7 6.7 7.4 9.6 3.3 8.9 5.0 2.1 7.1 8.4 5.0 4.8 7.7 6.2 6.1 9.3 5.5 2.8 7.5 3.6 4.7 8.6 9.6 10.9 4.4 10.5 7.6 20.6 11.2 16.8 8.0 10.8 9.0 16.9 10.1 9.4 11.8 15.3 11.3 9.9 9.2 10.6 10.4 13.1 14.2 13.1 2.6 2.6 4.7 3.0 2.6 2.3 2.4 2.3 2.6 2.0 2.5 4.0 49.8 51.3 34.5 6.5 53.3 110.1 96.2 151.8 58.6 43.5 53.8 66.2 18.0 67.2 79.6 58.8 25.0 110.8 41.3 60.3 117.4 66.6 118.4 73.6 62.3 58.0 48.6 52.2 7.4 54.6 79.7 51.1 35.7 56.6 51.3 63.6 47.2 133.4 69.0 53.8 8.1 63.4 85.5 59.3 62.6 38.6 75.8 50.4 58.7 7.5 74.6 52.9 66.9 12.1 12.5 59.9 97.2 55.3 36.3 76.2 61.6 190.5 91.1 50.1 52.6 57.1 58.4 66.6 53.9 67.1 134.1 95.6 46.8 125.7 82.3 105.7 MPP5 "FLJ12615, PALS1" ENSG00000072415 "Membrane palmitoylated protein 5" Q8N3R9 14 67240713-67336061 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000993, HPA063890" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA000993: AB_1079407, HPA063890: AB_2732707" "unprognostic (3.65e-1)" "unprognostic (3.82e-3)" "unprognostic (4.56e-2)" "unprognostic (9.20e-2)" "unprognostic (9.86e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.93e-3)" "unprognostic (9.89e-3)" "prognostic favorable (1.71e-12)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (6.90e-2)" "unprognostic (6.87e-2)" 7.4 8.7 13.9 6.3 20.9 5.6 10.6 17.6 16.5 8.8 26.6 12.7 20.4 6.3 21.1 13.6 7.3 7.9 7.4 11.9 17.4 31.4 19.6 12.3 4.8 18.2 18.2 6.1 8.7 19.6 7.2 9.8 18.3 16.2 12.0 17.2 18.4 12.7 18.0 8.4 20.7 7.2 18.1 6.6 9.4 8.8 17.5 10.3 25.1 13.6 6.1 9.0 8.4 27.5 156.4 24.4 24.1 18.5 13.3 12.3 20.6 46.4 23.6 33.2 21.6 23.8 45.9 12.7 21.5 37.8 11.0 31.0 13.9 26.1 50.2 5.5 9.5 11.8 23.6 16.8 15.5 4.5 8.5 13.1 10.0 17.9 23.7 24.2 19.0 13.5 12.6 4.7 53.9 20.4 14.4 5.0 7.7 22.2 16.2 12.2 37.1 15.2 30.1 36.8 13.2 9.4 28.2 27.0 15.5 21.1 28.6 9.2 29.2 41.4 87.2 13.8 19.9 7.8 7.6 19.3 27.2 10.1 14.7 0.1 0.5 0.8 0.4 1.0 0.3 1.1 0.5 0.6 0.8 0.4 1.1 0.6 0.0 2.2 0.7 0.6 0.3 0.4 13.9 20.9 17.6 16.5 11.9 17.4 18.2 18.2 18.3 18.1 17.5 27.5 13.2 64.1 28.9 37.2 8.8 21.0 26.0 14.6 22.2 8.5 22.4 12.8 24.7 11.5 21.1 22.0 43.8 23.1 5.2 47.2 13.7 21.7 5.9 29.5 15.0 17.7 5.4 6.7 24.8 26.9 11.3 17.3 18.3 46.2 5.1 15.8 17.2 20.7 17.6 3.3 34.7 21.2 12.2 11.9 13.4 4.5 8.1 9.2 3.6 22.5 6.6 23.4 3.1 41.2 129.8 26.7 32.5 11.3 13.1 30.1 54.3 33.5 14.9 34.3 6.6 17.7 22.2 22.4 36.1 29.2 17.3 17.5 7.7 7.5 22.4 38.7 MPPED2 "239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638" ENSG00000066382 "Metallophosphoesterase domain containing 2" Q15777 11 30384493-30586872 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5;thyroid gland: 24.6" "Cell type enhanced" "Detected in many" "Astrocytes: 155.7;Cone photoreceptor cells: 285.7;Excitatory neurons: 108.1;Horizontal cells: 82.4;Oligodendrocyte precursor cells: 345.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 21.6;HAP1: 12.2;JURKAT: 10.9;RT4: 9.0;SH-SY5Y: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062575 Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Vesicles, Mitochondria" "HPA062575: AB_2684797" "unprognostic (9.60e-3)" "unprognostic (6.12e-3)" "unprognostic (3.70e-3)" "unprognostic (4.56e-2)" "unprognostic (5.46e-2)" "unprognostic (5.04e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-2)" "unprognostic (1.13e-1)" "unprognostic (7.98e-4)" "unprognostic (6.82e-2)" "unprognostic (2.47e-7)" "unprognostic (3.64e-3)" "unprognostic (2.50e-1)" "unprognostic (2.22e-2)" "unprognostic (2.57e-2)" 2.0 5.2 6.3 0.5 13.3 0.3 4.1 4.7 10.5 24.5 0.9 4.9 0.7 6.4 5.6 0.9 8.9 1.0 3.7 11.9 13.0 9.6 0.4 0.4 0.2 19.6 10.3 0.5 1.6 3.2 11.0 1.6 11.7 12.6 0.6 16.0 10.3 7.4 5.1 0.7 1.0 3.6 4.9 2.3 1.7 1.7 9.5 3.6 24.6 1.5 0.3 3.3 5.1 6.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 12.2 0.0 0.0 0.0 2.6 0.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.9 0.0 0.3 3.5 0.1 0.1 0.0 3.4 0.2 0.0 9.0 0.1 6.5 0.0 0.0 3.6 1.3 1.8 0.0 0.1 0.0 1.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.2 0.1 0.4 0.5 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.3 13.3 4.7 10.5 11.9 13.0 19.6 10.3 11.7 4.9 9.5 6.8 3.1 0.0 2.2 155.7 1.8 1.0 51.7 2.6 2.8 26.7 3.6 5.2 5.2 0.0 1.0 46.0 285.7 0.3 0.5 0.1 25.4 4.2 2.1 35.6 1.5 6.3 0.0 1.3 108.1 0.0 0.2 2.6 0.0 13.8 5.1 12.1 0.7 0.2 4.1 82.4 56.0 0.3 2.0 22.5 3.6 1.6 0.3 2.7 5.4 13.1 0.5 44.0 0.0 345.8 7.9 0.1 0.1 3.4 0.5 19.3 0.0 3.1 3.0 18.5 0.0 1.2 7.1 0.1 2.1 1.5 1.1 0.5 0.8 0.4 0.0 28.4 MRI1 "MGC3207, MRDI, mtnA, Ypr118w" ENSG00000037757 "Methylthioribose-1-phosphate isomerase 1" Q9BV20 19 13764522-13774282 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042744, CAB045988" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 880000 "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "CAB045988: AB_2145566, HPA042744: AB_2678141" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-3)" "unprognostic (1.61e-1)" "unprognostic (8.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.75e-2)" "unprognostic (1.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" 15.8 19.2 7.9 9.0 8.2 9.5 18.5 9.3 8.5 24.8 7.0 17.3 9.6 21.6 4.1 20.5 21.8 5.3 12.9 7.6 7.5 22.3 23.8 15.8 10.5 8.9 7.7 24.4 19.6 7.8 18.0 11.9 8.7 19.3 6.4 5.3 20.5 8.8 11.6 26.0 21.1 5.2 7.1 23.1 18.3 3.6 8.4 7.8 23.0 4.4 8.7 17.6 22.4 10.9 14.7 9.3 5.5 13.1 6.1 9.5 13.0 17.9 9.3 13.8 12.4 9.9 11.5 7.9 6.5 6.6 7.3 25.4 24.5 15.5 10.8 12.6 39.3 6.6 18.5 12.0 4.7 20.3 14.8 9.9 9.4 7.1 6.0 14.3 13.7 7.9 11.6 0.6 7.4 18.7 21.9 14.3 9.1 6.0 27.2 20.5 7.6 17.4 8.1 11.4 10.4 9.9 6.6 13.9 14.5 7.7 11.1 8.2 8.2 8.2 7.6 29.3 8.8 11.0 11.3 2.4 6.8 22.5 9.7 3.4 1.8 0.7 1.7 1.7 1.8 1.5 1.7 2.2 1.4 1.6 1.3 1.1 1.6 1.8 1.1 2.7 1.5 1.3 7.9 8.2 9.3 8.5 7.6 7.5 8.9 7.7 8.7 7.1 8.4 10.9 9.2 9.6 19.8 15.0 10.8 11.1 8.9 10.8 6.8 4.3 9.0 8.4 0.9 8.6 13.4 16.5 8.4 13.2 17.2 8.1 5.9 9.2 0.7 11.5 14.4 13.8 9.1 13.3 22.3 12.7 8.7 12.3 14.3 14.2 13.3 9.9 12.8 10.0 7.2 1.7 19.6 9.3 6.1 7.2 8.4 1.7 17.4 7.4 1.8 9.4 10.5 5.0 17.5 18.1 15.2 6.8 11.0 15.1 13.3 4.7 16.5 10.5 19.2 9.3 26.3 10.8 13.3 0.3 4.5 13.3 11.4 5.3 16.0 22.2 9.8 6.8 MRPL44 "FLJ12701, FLJ13990" ENSG00000135900 "Mitochondrial ribosomal protein L44" Q9H9J2 2 223957463-223967714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038147, HPA038148" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA038147: AB_10671521, HPA038148: AB_2675863" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (3.38e-2)" "unprognostic (3.00e-1)" "unprognostic (7.05e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.16e-2)" "unprognostic (3.32e-1)" "unprognostic (7.65e-2)" "unprognostic (8.33e-2)" "unprognostic (6.65e-2)" "prognostic favorable (2.02e-4)" "unprognostic (2.47e-2)" "unprognostic (1.14e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-1)" 16.2 26.9 16.2 14.9 17.4 45.4 17.6 17.1 20.3 12.9 19.0 21.8 19.3 12.7 13.2 18.0 16.3 17.5 33.8 17.1 18.8 37.4 39.3 12.5 32.5 16.2 16.1 15.2 17.4 19.7 11.6 20.0 16.8 15.3 22.9 10.0 16.1 13.2 42.6 15.7 17.9 14.4 17.5 17.8 16.2 18.2 17.8 21.4 16.2 40.6 26.5 17.1 11.5 17.9 27.3 22.6 33.1 38.3 30.6 36.1 52.4 30.0 33.6 48.0 50.4 81.0 33.4 41.1 31.9 26.0 43.9 35.3 54.5 41.5 44.1 39.0 38.7 45.0 24.0 64.4 44.9 50.0 33.1 42.5 50.9 29.1 38.7 40.4 47.8 41.4 43.7 31.6 38.9 31.9 37.8 62.9 49.4 54.8 23.6 43.8 40.6 25.5 64.3 22.8 45.0 25.7 22.0 49.0 74.8 48.6 41.4 71.2 31.5 31.8 24.7 27.3 24.5 34.5 25.9 58.7 32.2 47.4 35.6 55.7 44.5 35.3 28.5 44.8 36.5 45.9 30.4 34.4 42.2 42.3 36.5 32.3 58.1 33.8 41.2 33.9 33.7 36.3 16.2 17.4 17.1 20.3 17.1 18.8 16.2 16.1 16.8 17.5 17.8 17.9 11.7 6.4 13.1 3.9 31.3 17.8 27.4 52.6 23.9 17.3 15.6 17.4 10.4 27.1 30.0 27.6 0.0 95.3 29.5 25.0 82.2 45.3 8.1 17.1 22.3 20.7 13.1 26.5 6.5 35.1 64.8 24.9 14.3 26.6 18.4 22.0 20.7 51.5 46.6 11.8 6.9 22.0 48.8 33.3 14.5 7.9 18.0 25.4 33.8 4.7 35.3 16.5 20.6 7.5 9.7 37.2 18.1 18.0 24.8 21.7 23.6 106.1 25.6 12.7 19.7 14.2 18.8 41.1 56.3 22.8 16.6 48.7 20.9 40.9 28.3 37.6 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 60.1;Distal tubular cells: 56.7;Ductal cells: 50.9;Exocrine glandular cells: 60.3;Hofbauer cells: 48.1;Pancreatic endocrine cells: 53.7;Proximal tubular cells: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003634, HPA076987" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Nucleoplasm, Plasma membrane" "HPA003634: AB_1851388, HPA076987: " "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 22.7 36.3 22.1 18.0 22.8 22.8 24.6 24.4 23.0 17.1 31.9 25.9 19.1 19.4 18.2 32.1 17.5 13.1 49.1 21.9 23.6 34.7 47.2 16.3 24.4 23.4 22.6 14.2 27.4 25.0 14.0 19.3 23.4 18.6 22.8 11.2 21.8 18.6 79.0 28.4 21.7 18.8 23.3 21.6 26.0 10.5 22.9 18.3 18.7 50.3 23.8 24.5 19.9 24.5 81.1 111.4 36.5 42.1 38.3 37.9 50.5 46.7 50.7 95.7 80.7 86.3 49.5 56.0 37.3 46.8 58.9 56.3 75.6 80.7 100.2 28.1 87.7 43.8 50.5 72.2 72.5 92.5 28.8 40.9 37.8 63.3 101.0 32.3 73.8 57.0 71.7 39.9 54.8 100.9 80.7 63.4 27.5 125.3 147.1 41.2 64.8 81.2 71.1 58.5 33.5 64.1 40.3 72.5 92.9 46.7 97.5 75.6 31.6 50.8 56.0 54.3 89.7 41.0 34.8 63.2 58.5 102.5 43.5 26.6 41.2 21.4 30.8 40.9 27.1 33.8 38.0 31.4 55.3 29.3 27.8 31.1 4.0 42.2 36.1 37.2 67.2 42.5 22.1 22.8 24.4 23.0 21.9 23.6 23.4 22.6 23.4 23.3 22.9 24.5 18.8 32.1 8.7 0.0 4.3 0.0 0.0 0.0 0.0 0.0 22.5 32.8 0.0 0.0 8.1 25.8 0.0 60.1 11.4 0.0 56.7 50.9 0.0 29.3 18.3 8.4 0.0 0.0 0.0 60.3 40.5 8.9 0.0 19.0 1.3 22.3 0.0 0.0 48.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 15.0 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.8 0.0 0.0 121.1 21.1 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 29.1 7.4 43.5 0.0 0.0 MRTO4 "C1orf33, dJ657E11.4, MRT4" ENSG00000053372 "MRT4 homolog, ribosome maturation factor" Q9UKD2 1 19251805-19260128 "Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026446 Approved Approved "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" Nucleoli "HPA026446: AB_10601441" "unprognostic (3.99e-1)" "unprognostic (1.75e-1)" "unprognostic (2.18e-2)" "unprognostic (2.94e-1)" "unprognostic (4.12e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (1.56e-8)" "unprognostic (7.46e-2)" "unprognostic (5.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.69e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.11e-8)" "unprognostic (5.87e-2)" "unprognostic (1.16e-1)" "unprognostic (2.50e-1)" "unprognostic (3.23e-2)" 18.9 18.5 17.0 16.8 17.1 13.4 20.2 14.8 17.9 13.0 13.7 13.5 16.8 15.8 12.9 23.7 17.6 8.9 14.4 17.4 16.1 17.9 20.3 11.1 20.0 15.8 16.0 17.0 23.4 12.5 8.9 12.1 16.1 12.9 16.5 7.2 12.3 10.5 22.7 17.4 19.5 16.7 15.4 13.8 15.5 14.0 16.1 14.8 11.1 11.4 22.8 21.4 14.1 16.4 90.9 65.9 51.1 67.0 24.2 38.6 44.7 69.0 38.9 116.7 76.1 92.9 92.0 133.6 56.7 60.5 50.4 70.1 142.7 104.6 114.0 47.4 109.6 98.4 55.4 80.8 30.3 133.4 38.7 34.0 69.8 131.6 69.6 31.7 66.1 59.0 151.1 42.3 68.9 68.0 106.3 96.5 65.0 95.6 95.4 99.3 62.7 100.5 64.8 31.3 82.9 59.2 54.0 73.0 75.4 37.6 50.8 76.5 44.2 61.9 77.5 97.6 118.0 33.8 64.3 178.2 61.2 172.4 102.5 1.4 11.6 1.3 11.4 12.7 22.9 23.1 13.7 15.9 17.6 19.7 18.4 16.7 1.4 16.6 10.2 19.7 10.6 11.4 17.0 17.1 14.8 17.9 17.4 16.1 15.8 16.0 16.1 15.4 16.1 16.4 30.0 6.4 14.5 6.2 31.2 37.3 59.1 45.8 42.7 20.4 23.6 37.7 10.3 38.6 26.4 7.3 10.4 50.4 14.9 15.7 41.1 61.8 23.3 19.1 46.8 32.1 21.6 31.3 8.4 55.0 69.9 29.5 19.4 21.1 26.0 36.8 15.4 16.3 47.1 15.2 7.3 25.4 36.7 13.3 18.2 36.5 23.0 21.0 19.6 1.9 32.0 25.7 16.5 4.5 4.3 57.5 17.0 20.3 29.0 57.4 6.0 37.9 15.8 16.4 19.7 44.8 35.9 55.6 49.7 48.2 33.5 26.0 18.6 58.1 34.8 36.7 MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 254.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 1139.3" "Cancer enriched" "Detected in some" 8 "colorectal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: AB_2683491" "unprognostic (2.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.83e-1)" "unprognostic (9.20e-3)" 0.2 0.0 0.0 10.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 234.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 254.3 0.0 0.0 0.5 0.0 0.0 0.3 4.8 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1139.3 0.0 0.0 0.4 0.1 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.6 0.1 27.8 0.0 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MTMR10 FLJ20313 ENSG00000166912 "Myotubularin related protein 10" Q9NXD2 15 30938941-30991628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 86.2;Oligodendrocytes: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006081 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" Cytosol "HPA006081: AB_2667508" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (7.36e-2)" "unprognostic (4.43e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-1)" "unprognostic (3.31e-2)" "unprognostic (6.43e-2)" "unprognostic (2.54e-1)" "prognostic favorable (7.77e-12)" "unprognostic (9.92e-2)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-1)" 18.6 9.5 29.3 10.7 46.9 18.7 10.3 49.4 33.3 11.2 24.8 9.9 12.8 9.4 9.4 20.9 7.5 9.6 12.7 28.0 36.3 30.6 24.2 13.6 12.0 57.6 48.5 11.5 12.4 21.3 1.9 25.9 56.5 11.0 10.3 12.1 14.9 11.4 29.4 11.2 11.6 10.0 45.3 15.1 13.0 8.5 40.8 16.7 14.2 24.0 10.6 10.1 5.4 63.3 8.1 9.0 8.2 5.2 17.7 9.6 7.2 11.9 23.9 9.4 9.4 5.9 3.5 3.9 15.5 15.5 9.1 11.5 6.5 7.0 8.9 12.5 2.1 5.5 6.2 10.4 10.3 8.9 12.2 13.2 5.4 6.1 6.7 10.8 23.7 10.9 4.9 9.2 8.9 2.3 9.3 5.6 4.7 9.7 4.3 6.7 6.7 19.5 35.6 12.7 3.0 7.8 5.4 6.3 2.4 10.4 4.2 16.4 10.9 10.6 8.0 5.6 6.8 9.4 7.8 9.0 6.7 4.7 13.4 3.7 3.2 3.1 0.7 4.0 0.8 1.9 0.8 0.6 3.1 2.8 1.2 1.2 13.5 1.4 7.4 3.7 1.2 1.7 29.3 46.9 49.4 33.3 28.0 36.3 57.6 48.5 56.5 45.3 40.8 63.3 15.8 25.6 15.2 86.2 11.3 8.9 4.3 3.3 8.0 0.0 6.7 4.6 24.1 10.0 7.0 33.1 0.0 19.3 12.9 12.7 1.9 3.4 13.6 10.1 9.6 16.8 6.0 5.2 15.4 3.8 3.1 8.6 13.3 19.7 17.1 9.4 11.4 33.9 11.8 0.0 13.6 7.7 2.0 24.9 16.2 24.9 10.5 19.0 8.8 55.3 13.8 0.0 3.1 25.6 149.3 5.6 9.2 7.5 8.0 6.7 14.4 18.6 4.7 0.0 0.0 10.6 8.9 11.1 8.9 33.6 11.1 38.4 6.8 6.7 8.2 8.7 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.1;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 11.2 10.6 5.1 9.5 11.2 5.7 6.3 10.1 10.9 7.2 3.4 8.3 8.9 11.7 12.3 9.3 9.6 11.8 14.4 6.5 9.0 18.7 19.4 13.1 11.1 10.9 10.4 11.4 11.9 12.8 6.7 10.8 10.6 9.0 10.1 19.2 10.5 7.1 28.9 9.1 10.2 12.0 8.2 6.7 6.7 7.1 9.3 7.5 9.0 32.9 10.6 14.4 5.5 20.0 19.3 18.1 10.2 20.0 34.0 13.6 25.1 31.1 18.5 16.5 15.4 27.8 15.1 32.6 27.9 24.6 27.4 11.8 17.0 14.2 27.9 22.9 15.8 14.6 62.0 15.3 21.9 23.4 6.8 18.3 11.4 24.6 18.4 20.4 10.4 8.0 21.9 24.2 9.8 4.2 14.2 11.7 7.3 29.4 19.0 12.4 9.5 14.1 16.2 16.0 14.0 2.5 51.6 33.7 28.6 18.1 10.7 17.5 14.6 31.9 19.7 24.1 22.7 34.7 13.5 27.3 23.1 50.5 19.1 5.3 4.0 3.0 4.1 5.5 7.0 3.3 6.5 5.7 3.6 3.3 4.1 3.6 0.1 3.1 4.4 2.3 9.1 3.3 5.1 11.2 10.1 10.9 6.5 9.0 10.9 10.4 10.6 8.2 9.3 20.0 7.7 16.0 70.1 10.1 11.1 16.3 9.4 4.6 12.0 0.0 9.7 5.1 12.9 5.7 9.0 9.2 0.0 9.9 11.4 11.0 21.5 10.2 50.1 10.0 10.7 8.0 9.6 12.4 25.4 5.5 8.9 11.8 9.2 6.7 10.2 6.5 8.6 19.3 7.7 0.0 20.8 9.1 0.0 11.1 9.4 99.2 10.5 9.7 1.8 15.0 8.1 0.0 7.2 20.1 50.9 7.2 6.0 11.7 26.5 14.3 8.7 28.9 10.1 0.0 6.6 10.7 10.1 17.4 13.1 10.5 20.6 11.2 13.8 11.8 9.4 8.7 MUC20 "FLJ14408, KIAA1359" ENSG00000176945 "Mucin 20, cell surface associated" Q8N307 3 195720884-195741123 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.5;kidney: 69.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.2;Ductal cells: 55.5;Ionocytes: 152.5;Respiratory ciliated cells: 66.5;Urothelial cells: 84.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SK-BR-3: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042249 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042249: " "unprognostic (1.85e-1)" "unprognostic (4.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.83e-3)" "unprognostic (2.12e-1)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.41e-1)" "unprognostic (3.99e-4)" "unprognostic (7.66e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.17e-1)" 6.7 5.1 4.3 1.3 5.0 0.9 7.9 7.0 6.7 23.0 3.0 30.0 3.0 5.0 4.5 58.5 20.0 6.4 6.3 3.6 3.4 69.7 21.1 7.9 0.8 4.1 2.7 11.8 16.1 2.0 16.5 0.5 4.0 20.9 7.2 8.1 40.3 1.1 7.0 8.0 14.7 0.8 1.4 6.1 9.8 8.5 4.2 0.8 16.2 1.0 1.4 21.0 26.0 5.0 0.9 0.0 0.2 0.7 0.4 0.0 0.7 0.0 0.2 0.0 0.1 0.0 3.7 0.1 0.7 0.0 0.2 1.5 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.4 0.1 0.7 3.9 0.1 1.0 0.1 1.1 0.1 3.6 1.3 0.4 0.0 28.1 0.2 0.5 0.2 0.0 0.0 0.2 0.8 1.0 0.1 1.3 1.7 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 7.0 6.7 3.6 3.4 4.1 2.7 4.0 1.4 4.2 5.0 0.9 35.3 16.7 16.6 0.5 1.8 10.0 6.4 0.6 19.9 3.2 1.5 0.7 14.3 43.7 22.0 35.5 0.1 0.2 53.2 1.9 55.5 0.1 3.5 1.3 1.7 13.8 5.3 7.5 9.9 0.1 1.8 13.3 6.2 1.3 5.3 3.3 7.3 0.5 11.8 7.7 7.3 152.5 1.0 0.8 0.4 5.3 1.1 3.6 1.0 0.0 4.7 0.0 5.0 3.0 12.2 16.9 6.4 1.7 14.2 16.9 3.3 66.5 20.5 0.0 8.8 3.3 1.3 1.3 4.3 1.8 0.0 1.7 1.0 15.2 84.4 MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508151 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favorable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" 16.7 18.1 18.1 12.0 18.7 28.8 16.2 19.9 19.4 15.9 23.3 21.2 14.2 20.4 11.1 21.2 19.6 14.9 33.7 17.8 19.4 19.5 24.6 15.8 13.6 20.3 19.1 19.1 19.8 36.3 14.6 16.3 20.1 16.0 15.7 7.4 19.3 20.0 35.5 21.8 15.8 20.0 18.7 15.2 18.7 12.2 19.5 12.0 16.2 50.4 15.0 19.2 15.5 19.9 34.1 32.1 18.1 37.9 38.5 21.6 19.6 32.9 39.1 40.1 38.2 19.9 54.8 25.4 35.9 46.8 30.4 50.3 32.9 47.5 28.9 25.4 26.1 19.4 20.4 29.2 45.2 27.0 32.0 35.3 61.6 41.1 42.3 23.4 26.5 22.5 25.8 30.1 44.1 17.3 16.4 18.1 18.7 28.1 30.3 15.8 22.8 32.9 47.1 18.7 18.4 27.3 29.6 31.2 40.5 14.6 22.0 25.6 30.2 38.8 22.3 34.1 29.9 34.9 32.9 27.3 30.4 36.1 36.7 36.2 30.0 38.2 33.1 34.7 34.4 25.3 24.8 33.8 29.6 22.8 28.1 27.6 26.7 32.3 30.7 22.8 37.9 34.0 18.1 18.7 19.9 19.4 17.8 19.4 20.3 19.1 20.1 18.7 19.5 19.9 14.5 22.4 10.3 10.4 9.8 5.2 9.2 13.9 5.2 13.5 12.3 11.9 16.6 10.0 9.5 18.4 6.2 37.1 13.2 21.6 11.7 26.3 2.2 7.7 9.5 13.1 8.5 8.6 4.9 23.4 22.5 13.9 7.7 9.4 3.8 14.7 13.6 17.6 23.0 13.5 6.8 12.9 16.2 10.0 6.5 4.0 13.1 9.3 19.6 2.8 15.5 16.0 16.5 5.5 6.0 25.6 14.6 15.4 13.1 9.2 13.2 10.6 9.6 11.9 19.7 11.9 14.7 14.6 15.4 7.4 7.1 37.6 9.2 18.0 12.2 10.7 MXD1 "bHLHc58, MAD, MAD1" ENSG00000059728 "MAX dimerization protein 1" Q05195 2 69897688-69942945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 173.4;esophagus: 130.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 507.0;Langerhans cells: 224.8;Paneth cells: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 496.3" "Lineage enriched" "Detected in all" 49 "granulocytes: 496.3" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001599 Enhanced Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA001599: AB_1079434" "unprognostic (1.59e-1)" "unprognostic (5.11e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (8.14e-6)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-3)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.50e-4)" "unprognostic (8.72e-2)" "unprognostic (3.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.56e-3)" "unprognostic (1.77e-2)" 13.5 3.6 6.2 40.4 6.9 173.4 7.0 10.0 15.8 35.2 6.4 30.3 28.8 5.4 1.9 130.0 8.1 9.4 8.3 6.5 7.8 6.8 11.3 36.5 3.9 7.1 6.3 6.1 4.6 6.8 6.7 10.9 8.1 5.5 28.9 15.6 17.4 2.0 6.0 12.8 43.7 9.1 5.4 32.8 16.9 6.3 10.7 13.9 7.5 6.5 15.1 17.4 50.6 10.5 5.0 2.1 3.0 2.2 6.5 3.2 11.2 5.5 3.1 2.6 1.9 6.8 3.8 2.8 2.8 2.1 2.5 17.3 5.8 10.7 2.7 1.6 6.9 5.9 6.6 7.0 21.9 7.3 5.7 3.7 17.8 5.9 27.0 3.2 3.4 2.8 10.4 10.9 1.6 4.0 3.4 14.1 0.8 7.3 3.5 1.6 3.1 7.1 3.4 5.8 9.8 4.1 7.3 9.3 3.9 3.4 1.4 4.1 13.2 3.7 1.0 4.1 5.2 7.5 13.7 1.1 3.8 12.5 1.4 124.0 10.2 105.7 2.3 6.4 2.5 1.1 1.6 1.7 5.2 1.3 1.8 1.9 496.3 2.8 5.5 1.6 1.5 4.5 6.2 6.9 10.0 15.8 6.5 7.8 7.1 6.3 8.1 5.4 10.7 10.5 18.0 38.5 23.7 16.0 25.4 25.7 31.6 61.8 21.6 29.8 51.6 29.3 6.9 10.0 44.7 1.8 54.2 10.1 46.2 507.0 7.9 12.9 17.0 34.3 17.5 12.0 97.5 17.7 23.6 16.5 8.0 17.9 110.1 81.6 27.3 3.0 5.7 6.8 28.6 10.1 20.2 155.5 71.2 56.5 224.8 17.8 4.7 190.8 16.0 11.2 40.7 62.1 18.6 20.1 21.7 70.1 369.6 2.6 33.1 43.3 178.8 6.9 24.2 21.7 0.0 14.7 18.3 19.9 2.7 88.2 56.4 105.9 30.3 5.2 65.9 126.7 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 MYBPH ENSG00000133055 "Myosin binding protein H" Q13203 1 203167811-203175826 "Predicted intracellular proteins" "Cell adhesion" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 16.2;skeletal muscle: 74.2;tongue: 19.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1.3;Hofbauer cells: 1.0;Microglial cells: 1.0;Skeletal myocytes: 2.5" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 20.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.5" "Group enriched" "Detected in some" 5 "CACO-2: 30.6;HSkMC: 56.7;THP-1: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061383 Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria NA NA 9700 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Mitochondria" Nucleoli "HPA061383: AB_2684497" "unprognostic (2.26e-4)" "unprognostic (2.04e-1)" "unprognostic (3.50e-1)" "unprognostic (1.06e-1)" "unprognostic (3.82e-2)" "unprognostic (1.32e-3)" "unprognostic (3.42e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-1)" "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (1.75e-1)" "unprognostic (7.62e-4)" "unprognostic (1.51e-1)" "unprognostic (3.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.74e-1)" 0.2 0.0 0.7 0.5 1.3 0.2 0.5 0.7 2.0 0.1 0.9 0.0 0.0 0.2 0.0 1.1 0.2 0.0 0.1 0.9 0.7 1.9 3.4 0.3 0.1 1.7 1.3 0.0 0.0 0.0 1.3 0.1 3.3 3.3 0.0 0.1 16.2 0.0 74.2 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.8 1.8 0.1 19.6 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 0.0 0.0 0.0 30.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 56.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.7 1.3 0.7 2.0 0.9 0.7 1.7 1.3 3.3 0.0 2.8 1.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 MYCBP2 "FLJ10106, KIAA0916, PAM, PHR1" ENSG00000005810 "MYC binding protein 2" O75592 13 77044657-77327094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 425.4;Inhibitory neurons: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA058807: AB_2732627" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 69.9 22.2 42.3 19.0 46.2 32.8 49.3 37.3 52.4 43.4 18.8 29.4 9.0 27.2 29.8 45.9 29.2 12.5 32.9 48.6 35.9 22.6 24.5 28.3 40.0 34.6 29.6 43.1 30.9 14.9 32.3 10.9 36.9 28.0 12.5 28.9 29.1 13.3 26.5 79.7 34.8 11.9 30.1 56.4 24.9 26.3 33.9 34.6 27.2 18.1 37.8 30.4 41.5 38.7 21.6 10.8 12.9 14.1 62.9 27.9 7.5 13.4 19.8 11.5 14.7 9.7 11.0 61.4 8.3 26.6 11.2 19.5 22.4 24.7 15.5 24.5 22.2 52.2 22.2 20.1 21.4 110.8 17.7 31.5 20.2 10.6 20.8 11.4 26.5 22.3 11.3 18.8 20.7 13.1 30.5 74.3 6.8 28.7 13.6 34.2 13.1 15.0 19.6 21.1 20.2 9.4 16.2 23.1 12.8 13.0 8.6 83.8 35.0 10.9 9.1 7.3 13.0 20.3 15.0 42.7 22.1 89.2 11.3 1.4 2.0 2.0 3.2 2.1 2.8 4.9 3.6 2.8 1.9 4.3 4.1 3.2 1.8 2.8 1.6 2.7 4.5 1.4 42.3 46.2 37.3 52.4 48.6 35.9 34.6 29.6 36.9 30.1 33.9 38.7 92.2 38.5 52.2 158.7 170.3 82.3 39.9 32.6 63.7 229.3 36.8 38.4 69.7 25.8 30.9 35.0 104.3 46.1 109.2 14.2 1.9 26.1 56.0 50.9 61.1 83.8 32.6 46.9 425.4 33.1 31.5 80.6 38.2 66.6 48.2 34.0 44.6 52.4 41.8 218.7 471.3 19.7 26.4 106.9 48.2 23.4 65.9 100.4 32.0 282.9 116.7 121.5 120.5 338.8 212.5 30.2 15.8 96.3 121.9 53.7 15.2 13.2 19.5 94.8 105.2 76.7 76.0 81.5 71.6 129.1 150.7 43.9 121.5 67.4 28.1 42.4 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750922 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 30.1;tongue: 72.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.8;Inhibitory neurons: 7.2;Microglial cells: 4.7;Oligodendrocyte precursor cells: 8.0;Proximal tubular cells: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEL: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 1.2 0.5 0.6 0.3 0.6 0.8 1.0 0.6 0.9 0.6 0.7 0.4 0.3 0.6 0.7 1.3 0.5 0.4 1.4 0.7 0.7 3.0 0.5 1.2 0.4 0.4 0.5 0.4 0.9 0.9 1.3 0.6 0.4 0.7 0.3 0.8 2.4 0.6 30.1 1.4 0.6 0.3 0.4 0.6 0.6 0.4 0.6 0.3 0.8 72.1 0.7 0.6 0.8 0.6 0.1 0.1 0.3 0.6 0.5 0.6 0.3 0.4 0.8 0.2 0.2 0.3 0.6 0.6 0.9 0.4 0.1 1.0 0.1 0.2 0.3 0.1 0.3 7.2 0.4 0.0 0.2 0.2 0.3 0.8 0.3 0.0 0.6 0.3 0.3 0.1 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.2 0.0 0.5 0.0 0.0 0.4 0.1 0.5 0.3 0.1 0.1 0.3 0.5 0.2 0.5 0.4 0.2 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.9 0.7 0.7 0.4 0.5 0.4 0.4 0.6 0.6 0.5 3.2 1.1 1.6 0.5 0.1 0.1 0.5 0.6 1.0 0.6 0.3 1.9 1.5 1.0 0.0 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.1 0.7 0.6 1.2 0.0 7.8 0.2 0.0 0.5 0.0 0.2 0.0 0.6 1.1 0.2 0.3 1.7 7.2 0.0 0.0 0.8 1.2 0.2 0.3 0.4 0.0 4.7 1.1 0.3 0.0 8.0 2.9 0.0 0.0 1.5 0.0 0.2 0.1 4.5 0.3 0.3 0.0 0.8 0.3 0.0 0.3 0.3 0.9 0.3 0.2 0.4 0.3 0.2 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYO10 KIAA0799 ENSG00000145555 "Myosin X" Q9HD67 5 16661907-16936288 "Plasma proteins, Predicted intracellular proteins" Transport "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.5;Muller glia cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.5" "Lineage enriched" "Detected in single" 5 "monocytes: 2.5" "Cell line enhanced" "Detected in many" "HeLa: 182.1;SK-MEL-30: 205.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015224, HPA024223" Enhanced Supported "Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli rim" "CAB015224: , HPA024223: AB_1854248" "unprognostic (1.13e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (7.63e-2)" "unprognostic (1.04e-1)" "unprognostic (4.43e-2)" "unprognostic (2.96e-2)" "unprognostic (4.40e-2)" "unprognostic (8.34e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-2)" "unprognostic (8.42e-2)" "unprognostic (1.85e-1)" "prognostic favorable (2.75e-4)" "unprognostic (8.93e-2)" "unprognostic (9.86e-2)" "unprognostic (4.56e-2)" "unprognostic (1.84e-1)" 13.8 3.0 47.4 6.2 46.3 3.2 7.9 24.6 41.1 6.7 55.1 19.3 22.8 6.2 3.5 9.3 4.3 8.4 4.5 39.8 24.8 14.7 7.7 19.0 1.3 32.6 30.9 15.8 32.2 10.7 9.5 31.5 27.6 5.8 19.1 15.1 11.0 5.0 8.2 15.6 19.5 4.9 27.3 13.9 32.0 15.6 46.4 4.9 37.5 4.4 2.0 11.1 7.8 45.7 68.2 108.3 31.3 14.9 24.7 17.0 35.1 117.2 89.2 35.5 27.4 63.1 10.2 1.5 78.9 52.9 42.3 33.4 139.1 73.7 57.1 0.2 16.7 0.1 182.1 13.7 81.5 0.4 1.5 30.9 26.8 78.5 92.1 57.4 110.5 0.2 0.2 4.8 28.7 10.5 0.2 0.4 80.5 56.6 37.2 26.1 10.3 66.9 22.0 49.6 5.2 2.8 27.0 11.4 205.0 53.2 8.1 9.1 137.8 77.6 23.6 0.7 61.1 0.7 0.5 0.5 38.3 11.2 76.2 0.5 0.2 0.2 0.1 0.5 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 0.3 0.1 2.5 0.1 0.1 0.1 47.4 46.3 24.6 41.1 39.8 24.8 32.6 30.9 27.6 27.3 46.4 45.7 53.5 35.3 34.6 158.7 1.4 40.9 31.0 23.0 29.6 11.0 18.6 11.6 3.8 55.8 26.3 31.3 18.8 20.4 0.3 46.4 17.6 110.8 30.2 118.5 20.8 61.3 74.0 0.0 3.9 40.6 63.4 13.7 68.3 116.0 27.8 189.5 77.1 1.7 5.6 82.4 5.4 53.2 20.3 7.1 4.8 9.5 12.8 5.7 67.6 87.1 3.8 233.8 0.0 103.5 23.5 114.7 50.3 19.2 0.4 42.6 28.3 4.2 18.8 9.2 65.7 8.2 31.5 3.8 12.2 30.7 31.8 147.8 2.4 4.1 66.9 38.6 MYO1E "HuncM-IC, MGC104638, MYO1C" ENSG00000157483 "Myosin IE" Q12965 15 59132434-59372871 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 319.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 23.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 224.1;HaCaT: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003003, HPA023886" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 13000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" Cytosol "HPA003003: , HPA023886: AB_1854253" "unprognostic (7.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.19e-4)" "unprognostic (1.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (5.38e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (2.41e-1)" "unprognostic (7.92e-2)" "unprognostic (7.31e-2)" "unprognostic (9.71e-2)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" 30.6 7.1 19.4 32.9 34.9 1.8 19.5 32.2 30.7 27.7 43.6 54.3 25.3 31.0 29.6 37.6 17.4 38.7 13.3 19.6 24.9 47.7 52.2 19.9 36.9 38.6 35.0 10.3 12.0 22.4 9.3 34.7 39.4 22.9 34.4 9.9 18.7 21.6 11.9 45.6 44.2 22.2 28.4 17.1 32.5 8.3 33.1 7.6 15.2 10.9 41.2 38.1 28.1 57.1 133.3 224.1 12.1 8.2 92.4 74.8 62.2 52.9 25.7 28.8 33.6 55.7 50.5 52.7 37.0 41.3 117.5 208.6 18.9 81.5 38.2 24.1 10.5 0.5 178.4 50.3 85.5 0.3 7.2 103.4 48.8 37.0 107.4 90.7 47.8 0.9 0.3 0.8 49.2 12.4 0.6 1.2 29.3 21.5 49.8 0.2 53.8 32.4 156.9 61.8 6.5 21.9 117.1 24.2 45.8 36.5 16.3 5.8 58.4 57.5 16.6 177.1 52.0 0.3 3.3 1.3 105.4 0.6 53.2 0.0 4.5 0.0 0.2 4.6 0.0 9.2 0.0 0.0 15.4 8.6 0.0 0.0 0.6 3.6 1.6 23.7 0.5 2.5 19.4 34.9 32.2 30.7 19.6 24.9 38.6 35.0 39.4 28.4 33.1 57.1 31.0 6.4 7.7 27.1 19.6 24.9 40.0 24.7 24.5 0.2 9.3 10.2 3.9 17.2 15.4 25.8 0.0 4.3 19.9 73.6 3.9 39.8 4.2 49.4 30.2 30.4 19.7 2.5 9.3 18.1 23.8 14.9 86.6 47.3 4.5 6.7 5.0 13.0 33.5 0.0 8.7 31.2 8.2 5.0 50.1 8.5 9.3 17.6 19.6 56.2 9.0 11.3 3.1 6.6 319.1 64.0 60.0 12.0 9.2 28.3 37.4 3.1 40.9 0.9 13.1 33.7 25.0 1.3 5.1 30.1 24.0 12.9 4.7 6.7 29.3 56.9 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 15.5;testis: 5.2" "Cell type enhanced" "Detected in some" "Early spermatids: 156.6;Late spermatids: 58.2;Muller glia cells: 74.8;Spermatocytes: 31.7" "Cancer enhanced" "Detected in many" "cervical cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CAPAN-2: 1.2;HEK 293: 1.5;SCLC-21H: 1.4;U-2 OS: 2.4;U-698: 6.3" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.4 0.0 1.8 0.1 0.1 0.0 0.8 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.6 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.7 0.0 0.5 0.0 0.5 0.1 0.3 15.5 0.0 0.1 0.0 0.7 0.1 0.0 0.2 0.0 0.2 5.2 0.3 0.2 0.2 0.1 0.2 0.0 0.3 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.8 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.8 0.1 0.6 0.6 0.5 0.5 0.2 0.3 0.3 0.2 0.0 0.5 2.0 0.1 1.8 0.3 0.0 0.0 0.9 0.6 0.3 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 1.9 0.8 156.6 0.6 0.1 0.3 1.8 0.0 2.2 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.4 0.0 0.0 0.0 58.2 1.2 0.1 0.0 1.9 0.0 74.8 0.0 1.0 0.4 0.2 0.0 1.2 0.0 0.3 0.0 1.0 0.0 3.9 0.0 0.0 2.4 31.7 14.2 2.4 1.0 0.0 0.0 0.0 0.4 0.3 MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 222.5;skeletal muscle: 321.5;tongue: 255.9" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 198.3" "Cancer enhanced" "Detected in some" "renal cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 4.6;Hep G2: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 830000 "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: AB_10599293, HPA028340: " "unprognostic (8.59e-2)" "unprognostic (2.85e-2)" "unprognostic (2.39e-1)" "unprognostic (8.60e-3)" "unprognostic (1.52e-2)" "unprognostic (7.31e-2)" "unprognostic (3.00e-2)" "unprognostic (1.40e-2)" "unprognostic (4.66e-1)" "unprognostic (2.21e-1)" "unprognostic (2.73e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.28e-6)" "unprognostic (2.77e-2)" "unprognostic (1.60e-3)" "unprognostic (7.75e-2)" "unprognostic (1.68e-1)" 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.3 0.1 0.2 0.0 0.6 1.1 0.3 0.0 6.0 0.9 0.4 222.5 0.1 0.1 31.4 0.2 0.3 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.1 4.5 0.7 1.2 7.1 0.0 321.5 2.2 5.2 0.2 0.0 0.0 0.2 9.0 0.0 1.7 0.3 255.9 0.1 0.1 0.4 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 1.3 0.0 1.9 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.8 18.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.2 0.1 1.0 0.2 0.5 0.6 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.6 0.2 0.1 0.6 0.0 0.1 0.6 198.3 0.0 0.0 3.7 0.0 0.0 0.1 3.6 1.9 0.1 16.2 0.4 0.0 1.6 1.2 0.0 0.4 0.4 0.0 6.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.7 10.3 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.5 2.4 0.0 0.0 0.2 13.0 33.2 0.0 2.5 6.6 10.0 1.3 0.0 0.2 0.0 0.6 0.0 0.3 2.3 2.2 0.3 MYPN MYOP ENSG00000138347 Myopalladin Q86TC9 10 68106117-68212017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 64.1;skeletal muscle: 283.6;tongue: 172.8" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 114.2" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 0.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "BJ: 39.8;fHDF/TERT166: 112.3;HBF TERT88: 25.6;LHCN-M2: 47.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA036299, HPA061494" Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" Cytosol "HPA036299: , HPA061494: AB_2684539" "unprognostic (4.75e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "unprognostic (8.62e-3)" "unprognostic (3.91e-1)" "unprognostic (3.36e-3)" "unprognostic (4.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.82e-1)" "unprognostic (2.26e-3)" "unprognostic (3.94e-3)" "unprognostic (3.10e-1)" "unprognostic (2.88e-8)" "unprognostic (4.63e-5)" "unprognostic (9.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.47e-1)" 0.1 0.3 0.2 0.2 0.1 0.6 0.1 0.5 0.2 0.0 0.0 0.3 0.1 0.1 0.1 2.2 0.0 0.1 64.1 0.8 0.8 0.0 0.0 0.0 0.2 0.6 0.2 0.1 0.6 0.0 0.0 0.1 0.1 1.7 0.1 1.7 2.7 0.0 283.6 0.1 0.1 0.2 0.0 0.1 0.8 0.9 0.0 0.1 0.0 172.8 0.0 0.1 0.0 0.3 2.9 1.3 0.0 0.0 0.7 4.1 0.1 39.8 19.7 14.4 5.4 0.0 0.1 0.1 0.0 112.3 20.5 0.7 0.0 0.2 25.6 0.4 0.0 0.0 14.6 0.0 0.3 0.0 0.1 1.6 0.0 7.9 0.9 3.6 0.4 0.0 0.0 0.2 47.6 8.6 0.0 0.1 0.0 0.0 1.3 0.0 2.2 0.0 0.1 0.1 0.1 0.0 5.7 0.9 0.2 0.1 0.0 0.0 1.1 0.7 0.2 4.1 0.1 0.1 0.0 0.0 4.6 0.1 4.2 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.2 0.8 0.8 0.6 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.2 0.0 114.2 0.0 0.0 0.0 25.0 0.0 0.0 1.8 0.0 0.0 1.0 1.5 0.1 0.7 0.0 0.0 0.5 0.2 0.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.4 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.1 MYRIP "DKFZp586F1018, exophilin-8, SLAC2-C, SLAC2C" ENSG00000170011 "Myosin VIIA and Rab interacting protein" Q8NFW9 3 39808914-40260321 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 295.6;Inhibitory neurons: 507.3;Microglial cells: 210.8;Oligodendrocyte precursor cells: 98.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.1;HUVEC TERT2: 15.6;REH: 3.7;SCLC-21H: 3.2;SH-SY5Y: 9.4;T-47d: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006433 Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "HPA006433: AB_10603023" "unprognostic (1.87e-2)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.89e-2)" "unprognostic (2.36e-1)" "unprognostic (6.03e-2)" "unprognostic (2.57e-3)" "unprognostic (1.34e-3)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (1.91e-1)" "prognostic favorable (3.96e-8)" "unprognostic (7.12e-2)" "unprognostic (2.40e-1)" "unprognostic (8.92e-2)" "unprognostic (6.16e-2)" 4.1 1.0 16.8 1.3 13.3 0.0 3.7 11.1 18.4 5.7 15.4 2.7 1.7 3.2 2.2 1.3 2.8 2.7 2.4 17.3 7.7 1.5 11.5 0.8 1.6 9.2 17.8 3.1 8.9 2.1 2.9 0.1 13.0 2.0 2.6 4.3 12.5 0.8 1.7 1.2 2.4 2.3 4.2 7.2 5.6 0.9 12.0 0.5 1.5 0.5 1.7 1.4 2.6 15.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.2 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.1 3.7 0.0 0.0 0.4 2.0 3.2 9.4 0.0 0.0 0.0 0.0 3.8 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 13.3 11.1 18.4 17.3 7.7 9.2 17.8 13.0 4.2 12.0 15.0 15.8 0.0 3.2 36.2 0.4 0.8 0.1 0.0 1.2 2.7 0.5 0.3 2.4 5.7 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.1 19.9 1.1 0.7 21.3 0.0 1.7 295.6 2.8 0.0 1.6 3.1 6.2 2.5 14.0 42.8 17.4 0.0 5.0 507.3 11.9 0.0 2.8 0.7 6.1 0.9 0.1 0.0 210.8 0.0 6.6 0.0 98.0 24.5 0.6 0.1 0.0 0.0 1.4 0.1 1.8 0.1 4.2 0.0 0.3 0.7 3.1 0.6 0.1 0.6 0.0 0.3 0.1 0.7 0.1 N4BP1 ENSG00000102921 "NEDD4 binding protein 1" O75113 16 48538726-48620148 "Predicted intracellular proteins" "Immunity, Innate immunity" "Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 134.6;Glandular and luminal cells: 113.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040849, HPA041080" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040849: AB_10794866, HPA041080: AB_10794186" "unprognostic (1.07e-1)" "unprognostic (2.17e-1)" "unprognostic (5.07e-2)" "unprognostic (2.50e-3)" "unprognostic (1.16e-1)" "unprognostic (3.19e-1)" "unprognostic (4.35e-3)" "unprognostic (9.18e-2)" "unprognostic (4.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.71e-1)" "unprognostic (1.35e-1)" "prognostic favorable (9.03e-8)" "unprognostic (9.00e-2)" "unprognostic (1.49e-1)" "unprognostic (1.96e-1)" "unprognostic (8.36e-2)" 9.3 6.7 8.0 7.3 7.8 10.3 9.0 9.7 8.0 10.2 7.9 8.8 5.9 8.6 8.3 18.9 8.4 6.3 7.9 7.6 11.0 7.4 7.0 14.7 7.5 8.5 7.8 9.7 7.6 11.4 9.1 7.5 8.2 8.8 6.3 6.9 10.7 6.4 10.5 19.9 9.3 6.3 7.1 10.9 9.2 4.7 10.7 10.3 8.3 7.9 9.0 8.1 11.3 8.4 7.1 11.8 8.3 8.5 11.4 9.0 6.9 6.5 9.9 12.4 6.3 9.3 5.8 7.9 5.9 10.0 5.5 14.4 7.5 10.3 6.8 4.9 6.2 4.1 4.7 8.3 11.1 6.2 10.8 13.0 15.5 4.4 6.4 9.1 6.3 8.1 6.4 8.2 7.5 4.0 7.4 11.2 6.6 7.3 6.7 11.1 13.5 12.4 6.2 11.9 9.3 6.6 5.5 10.0 9.2 8.6 4.2 8.5 9.3 6.3 5.6 3.5 3.9 12.2 7.8 12.0 7.3 4.9 5.6 0.9 1.3 1.8 1.0 1.2 1.3 0.9 1.3 1.6 0.8 0.6 1.1 1.1 8.4 0.4 0.9 1.0 1.0 0.6 8.0 7.8 9.7 8.0 7.6 11.0 8.5 7.8 8.2 7.1 10.7 8.4 41.2 134.6 32.7 28.4 15.3 20.0 21.6 32.4 19.4 24.1 21.3 21.2 15.1 22.8 25.8 7.3 16.7 13.4 53.8 35.4 5.9 8.4 6.4 36.8 35.8 25.7 9.6 6.5 47.5 13.2 10.5 20.1 30.5 113.8 12.6 23.1 24.3 13.4 19.5 26.9 50.1 21.2 6.1 25.9 40.3 3.7 16.1 36.5 5.4 58.1 31.9 15.3 21.6 38.7 54.8 26.7 21.6 20.7 30.2 30.6 16.1 9.4 18.4 23.0 0.0 26.3 17.6 12.6 24.4 26.8 22.7 28.5 36.5 23.8 13.4 47.5 N4BP2 B3BP ENSG00000078177 "NEDD4 binding protein 2" Q86UW6 4 40056850-40158252 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036770, HPA042607, HPA072549" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA036770: AB_10672477, HPA042607: AB_2678074, HPA072549: " "unprognostic (5.03e-2)" "unprognostic (3.42e-1)" "unprognostic (7.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-3)" "unprognostic (2.88e-1)" "unprognostic (1.01e-1)" "unprognostic (3.66e-2)" "unprognostic (2.65e-2)" "unprognostic (9.55e-3)" "unprognostic (4.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (6.85e-3)" "unprognostic (1.45e-1)" 1.0 0.7 1.4 2.5 1.2 4.1 2.9 1.8 1.6 2.5 1.7 2.2 2.4 3.4 1.9 1.8 1.8 1.6 1.1 0.7 4.2 1.5 5.8 1.6 3.6 2.1 1.7 3.0 4.2 1.4 1.2 3.6 0.7 2.4 2.2 2.2 3.5 0.9 0.7 1.9 2.2 0.8 1.4 1.9 1.9 1.8 4.0 11.3 3.5 1.0 4.1 2.1 1.4 0.5 2.0 2.0 12.0 1.9 0.8 3.8 9.5 2.2 2.5 1.3 2.7 3.9 4.0 10.7 4.3 2.1 2.2 1.5 7.7 2.4 3.0 3.4 2.3 4.8 1.5 1.8 1.9 13.0 11.2 4.3 3.3 2.1 4.6 0.4 3.3 10.0 10.8 4.5 2.5 1.9 26.8 6.4 6.0 1.6 1.7 15.4 14.1 2.5 1.0 4.7 4.7 8.3 2.2 1.6 2.1 7.8 1.5 3.8 4.5 1.5 7.3 0.9 1.7 7.4 8.0 7.3 1.4 4.8 3.0 5.1 0.8 0.4 1.7 0.9 1.8 1.2 2.3 1.3 1.4 1.7 3.4 1.9 0.2 8.2 0.9 6.5 1.1 0.9 1.4 1.2 1.8 1.6 0.7 4.2 2.1 1.7 0.7 1.4 4.0 0.5 9.6 22.4 24.4 19.2 18.2 12.0 14.3 5.1 18.8 33.0 12.3 11.2 12.3 11.5 13.2 22.0 27.1 44.2 36.7 9.0 0.0 6.0 4.7 17.6 15.1 11.4 19.3 22.5 16.5 12.6 12.9 15.5 12.2 20.7 5.1 36.1 6.8 20.7 12.4 72.3 47.2 17.1 10.2 16.3 24.6 4.3 9.9 24.0 7.2 36.5 17.9 12.4 27.8 44.2 3.1 11.4 10.8 3.8 36.0 12.4 7.3 3.6 8.7 22.6 13.1 17.9 6.3 22.0 24.3 13.0 13.1 27.0 28.4 30.4 8.5 9.2 NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N-alpha-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 2.6;placenta: 4.2;testis: 6.2" "Group enriched" "Detected in some" 12 "Cytotrophoblasts: 19.4;Early spermatids: 30.6;Extravillous trophoblasts: 16.4;Late spermatids: 23.9;Spermatocytes: 25.1;Spermatogonia: 15.9;Syncytiotrophoblasts: 13.3" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.1" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "GAMG: 19.3;K-562: 12.3;U-266/70: 32.9;U-266/84: 11.3" "Not detected" "Not detected" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA035922: AB_10673490" "unprognostic (7.37e-2)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.6 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.0 0.0 0.0 4.2 0.3 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.3 0.3 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.2 0.0 32.9 11.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.6 0.1 0.1 0.2 0.5 0.4 0.3 0.3 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 15.9 0.0 0.0 13.3 0.0 0.0 0.0 0.0 NAA35 "bA379P1.1, FLJ21613, FLJ22643, MAK10" ENSG00000135040 "N-alpha-acetyltransferase 35, NatC auxiliary subunit" Q5VZE5 9 85941146-86025462 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021547 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "HPA021547: AB_1853505" "unprognostic (5.87e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-3)" "unprognostic (9.25e-3)" "unprognostic (2.37e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.86e-1)" "unprognostic (5.22e-3)" "unprognostic (1.56e-1)" "unprognostic (8.30e-2)" "unprognostic (1.09e-1)" "unprognostic (2.36e-3)" "unprognostic (1.88e-1)" "unprognostic (4.34e-2)" "unprognostic (9.18e-2)" "unprognostic (1.07e-2)" 7.7 12.2 6.9 6.3 7.3 6.6 9.3 9.8 7.0 8.9 8.2 11.1 8.6 9.4 7.8 10.9 8.4 5.7 8.8 6.9 7.2 8.4 8.7 7.1 6.2 6.3 6.0 9.9 10.8 9.4 12.0 7.4 6.2 9.7 10.5 14.3 10.1 6.8 17.4 9.1 8.1 7.0 6.4 6.5 8.8 15.4 8.4 7.3 10.4 13.2 7.2 9.0 9.1 8.9 25.4 15.8 17.7 13.5 9.8 13.1 24.8 15.5 15.1 16.1 13.1 12.4 15.7 8.4 8.5 15.4 13.1 34.9 15.0 18.4 16.8 22.3 13.1 21.6 19.9 14.6 16.6 30.4 17.6 13.1 15.2 17.0 24.6 12.4 14.0 15.6 25.3 15.6 14.9 14.6 15.7 16.0 17.8 28.0 18.2 14.4 26.9 12.6 17.3 20.4 16.7 15.5 17.6 15.8 13.6 17.0 11.9 11.7 14.0 11.2 12.4 16.9 15.0 22.3 29.1 5.7 16.3 12.5 10.2 1.7 2.5 5.1 3.4 2.6 4.3 9.5 3.5 3.1 3.0 9.3 4.6 3.4 1.3 3.5 1.9 2.2 3.1 2.6 6.9 7.3 9.8 7.0 6.9 7.2 6.3 6.0 6.2 6.4 8.4 8.9 14.6 3.2 14.1 58.4 16.8 16.3 20.2 19.0 19.9 25.5 18.0 13.1 23.3 18.6 22.8 11.0 22.9 22.6 14.9 20.2 1.9 19.7 8.7 29.4 18.6 14.3 20.9 14.5 51.8 25.8 18.9 13.6 16.3 22.5 12.0 32.9 9.3 9.8 12.2 21.9 58.7 14.5 30.5 11.0 8.4 5.3 9.3 10.7 14.2 52.5 12.3 18.7 14.4 44.7 68.8 18.3 16.6 11.7 17.1 22.0 12.0 8.9 33.7 36.6 13.1 21.4 24.7 56.7 36.3 17.7 16.6 31.1 15.8 24.4 16.6 19.2 NAA40 "FLJ13848, NAT11" ENSG00000110583 "N-alpha-acetyltransferase 40, NatD catalytic subunit" Q86UY6 11 63938959-63957319 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 102.6;Late spermatids: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037816, HPA056142" Uncertain Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Centriolar satellite, Cytosol" "HPA037816: AB_10672289, HPA056142: " "unprognostic (3.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-1)" "unprognostic (6.88e-3)" "unprognostic (1.50e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (1.43e-7)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" "unprognostic (7.01e-3)" "unprognostic (6.29e-3)" "unprognostic (3.42e-2)" "unprognostic (6.43e-3)" "unprognostic (2.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.25e-2)" 3.3 8.9 5.1 3.9 5.1 2.5 4.4 4.5 5.7 4.0 5.7 5.2 5.7 3.0 3.3 6.7 6.8 3.6 9.5 5.3 4.9 9.1 3.8 3.6 7.5 5.6 5.3 2.7 6.5 15.1 10.4 6.7 5.2 4.2 4.7 7.2 6.6 4.0 4.7 2.7 5.7 3.1 5.0 8.8 4.8 15.3 5.2 10.0 6.1 8.5 7.3 4.2 3.6 5.0 15.5 17.3 21.7 11.8 6.0 5.9 13.8 11.3 12.0 27.3 19.1 14.8 19.3 9.5 13.6 10.2 18.9 13.7 18.3 8.2 20.1 12.5 11.2 13.0 11.1 16.9 7.9 20.9 10.8 6.0 7.4 17.0 4.6 10.6 18.0 16.1 22.4 6.9 12.9 11.8 22.3 16.3 20.2 14.3 11.8 21.9 19.5 12.1 18.5 11.8 28.7 15.1 17.7 15.2 9.2 15.8 25.1 9.2 11.6 15.1 18.3 8.9 9.3 8.3 5.6 16.5 9.2 8.9 11.9 2.3 0.5 2.7 6.9 0.4 2.4 2.7 1.8 3.3 2.7 2.4 1.1 2.6 0.1 5.2 0.2 3.5 0.5 2.3 5.1 5.1 4.5 5.7 5.3 4.9 5.6 5.3 5.2 5.0 5.2 5.0 4.3 3.2 4.8 12.1 8.1 2.8 2.0 4.5 10.8 30.9 11.5 7.0 14.8 5.7 9.4 18.4 33.3 9.6 12.1 13.6 0.0 5.7 46.3 20.0 7.4 7.6 17.5 7.4 14.3 5.4 12.8 4.8 6.1 8.5 1.3 14.3 9.7 5.2 9.5 102.6 15.6 6.1 10.2 10.3 5.3 130.5 4.7 7.3 1.8 15.0 4.4 8.6 17.5 11.6 10.1 5.9 3.5 7.2 12.2 2.1 10.6 4.1 22.5 23.9 0.0 4.3 4.4 27.4 16.5 6.5 2.8 4.1 8.9 10.4 7.3 1.8 NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" 29.3 20.3 19.4 23.5 16.7 18.6 34.8 50.4 23.5 28.1 7.4 22.8 15.8 32.3 50.1 36.3 27.5 28.0 28.5 18.7 9.7 19.9 37.8 22.8 26.8 13.4 13.2 26.0 17.9 23.5 21.1 26.4 14.9 18.5 25.6 41.4 20.7 20.9 8.0 66.7 17.1 25.2 14.9 19.8 37.9 26.0 13.8 21.2 37.9 17.2 26.3 31.2 24.2 25.9 35.5 25.8 65.0 22.6 24.5 42.7 111.0 35.5 55.7 26.4 29.8 62.8 38.4 39.6 40.6 28.3 48.9 88.4 37.4 45.9 51.8 126.1 31.0 46.7 96.3 30.2 15.8 19.8 22.4 24.6 70.4 55.9 17.1 37.4 41.5 23.9 46.3 33.2 40.6 17.4 28.7 20.0 22.8 38.4 35.2 35.0 46.7 15.9 19.3 34.5 57.9 46.9 41.8 13.9 37.3 82.8 11.4 30.6 29.0 54.5 43.0 31.0 21.6 25.7 30.3 29.5 57.3 17.6 43.7 0.0 1.3 0.6 1.3 1.1 1.9 0.7 1.3 1.7 0.9 0.4 1.4 1.5 2.9 2.6 3.7 0.8 3.3 0.8 19.4 16.7 50.4 23.5 18.7 9.7 13.4 13.2 14.9 14.9 13.8 25.9 24.1 6.4 21.2 14.0 5.9 102.0 23.1 24.6 31.3 26.1 19.7 19.7 18.2 11.5 29.8 12.9 12.5 4.3 9.2 11.4 3.9 10.3 1.4 17.5 10.8 30.1 14.4 12.0 37.2 8.0 11.1 25.2 21.4 23.4 20.3 14.2 44.6 25.7 6.7 6.7 21.2 17.5 14.2 17.3 77.4 3.2 13.4 20.7 39.2 24.4 10.6 12.4 11.3 29.1 28.3 10.2 26.3 14.7 14.9 30.5 4.8 5.1 22.3 15.5 46.0 24.6 39.2 1.7 27.3 55.7 138.9 1.2 16.7 7.3 16.0 29.9 NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: AB_2676060, HPA038524: AB_2676061" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (7.30e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.17e-6)" "unprognostic (1.19e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (4.12e-3)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "prognostic favorable (5.10e-4)" 29.5 34.1 18.8 24.1 20.4 67.6 26.2 18.5 21.2 30.4 20.3 48.6 39.5 26.0 24.2 56.3 31.2 25.8 20.3 17.8 18.3 33.2 49.8 35.3 33.3 22.4 19.6 27.6 29.5 13.4 36.0 16.5 21.0 45.3 36.0 6.9 32.9 22.8 11.0 31.1 51.1 19.3 18.8 58.4 34.3 25.6 21.7 27.9 31.8 5.1 28.2 43.4 33.4 24.4 15.9 37.8 12.0 21.6 35.0 50.6 32.4 29.7 27.2 15.4 17.0 32.4 25.7 13.4 33.1 35.3 20.7 55.2 15.9 42.6 8.2 27.9 12.8 22.2 27.6 36.3 43.3 45.1 40.9 72.0 65.8 19.9 17.8 34.9 54.6 24.2 11.9 18.5 21.9 49.7 22.4 29.9 7.0 69.6 21.3 27.5 37.2 13.5 37.8 72.1 8.9 12.7 21.2 27.9 56.0 17.9 24.9 24.4 66.2 16.7 14.2 30.9 11.8 24.3 11.0 11.7 29.9 25.6 12.0 6.1 28.0 17.3 15.3 25.0 12.7 12.2 13.5 13.8 31.1 9.2 8.8 11.4 17.7 16.3 22.6 23.0 17.7 21.4 18.8 20.4 18.5 21.2 17.8 18.3 22.4 19.6 21.0 18.8 21.7 24.4 12.6 22.4 32.3 4.2 24.0 6.2 17.8 18.4 26.2 7.8 13.5 10.9 8.3 12.8 19.8 11.0 4.2 17.4 27.3 65.3 3.9 16.5 22.6 21.1 11.1 15.6 23.4 20.2 5.1 17.3 14.5 12.8 51.0 19.7 22.1 23.1 13.9 16.7 20.1 13.5 5.8 30.3 16.2 23.2 18.5 60.9 9.3 25.4 8.8 8.4 25.8 5.9 29.9 7.5 18.5 20.0 55.8 10.1 18.0 17.9 73.3 16.2 16.5 7.3 13.1 9.6 9.8 15.9 5.0 38.3 12.8 17.2 22.3 17.1 43.7 24.2 NAE1 "APP-BP1, APPBP1, ula-1" ENSG00000159593 "NEDD8 activating enzyme E1 subunit 1" Q13564 16 66802875-66873256 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 219.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041178, HPA042041" Enhanced Approved Nucleoplasm,Microtubules,Centrosome NA NA 100000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Microtubules, Centrosome" "HPA041178: AB_10964773, HPA042041: AB_10964772" "unprognostic (3.22e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-2)" "unprognostic (1.13e-1)" "unprognostic (2.00e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (3.92e-8)" "unprognostic (2.31e-1)" "unprognostic (5.58e-2)" "unprognostic (3.12e-3)" "unprognostic (5.34e-2)" "unprognostic (3.85e-2)" "unprognostic (7.09e-3)" "unprognostic (2.50e-1)" "unprognostic (1.84e-1)" "prognostic favorable (9.44e-5)" "unprognostic (1.97e-1)" 23.9 28.3 26.0 26.0 26.0 38.8 32.5 28.8 29.6 23.0 27.1 31.9 32.4 32.9 35.2 30.3 26.8 24.2 29.7 25.5 27.1 26.5 28.6 22.5 36.1 25.8 26.1 35.6 27.3 41.5 22.6 28.4 27.1 28.8 35.3 33.9 25.9 26.7 35.0 33.1 33.2 30.3 27.0 22.2 21.6 47.1 27.1 35.0 32.3 33.0 31.6 28.6 22.1 30.3 107.6 81.1 140.4 139.4 55.1 78.9 116.9 79.9 80.3 115.6 139.8 99.5 80.9 118.1 89.1 60.4 74.8 105.6 107.7 96.5 162.0 43.8 122.1 83.9 53.6 153.9 63.2 157.3 100.7 64.0 69.6 92.8 80.7 61.0 82.5 141.2 201.9 40.3 89.9 37.5 165.7 177.7 196.2 83.4 144.6 175.7 167.8 157.7 89.1 92.6 151.3 110.6 239.5 50.7 94.7 86.0 54.2 105.2 64.7 80.2 80.1 84.7 93.9 75.3 125.3 423.8 72.3 103.0 99.7 2.8 6.0 13.4 27.3 5.8 34.9 18.2 29.0 30.1 8.2 14.4 31.0 31.4 2.7 17.1 6.5 12.2 27.4 18.3 26.0 26.0 28.8 29.6 25.5 27.1 25.8 26.1 27.1 27.0 27.1 30.3 29.2 32.1 32.2 23.5 30.1 33.0 66.6 87.2 17.1 52.0 28.4 31.4 30.7 18.6 53.4 31.3 12.5 101.3 33.9 28.0 39.2 70.0 4.6 27.7 23.2 30.7 22.9 38.9 41.3 60.2 70.9 38.4 20.9 22.9 35.4 55.9 19.2 21.3 28.6 50.5 40.7 33.3 67.1 10.4 13.5 14.3 48.7 16.2 49.8 17.8 25.7 68.4 51.5 33.2 39.8 65.0 114.3 54.2 32.0 68.8 34.7 48.2 44.8 35.9 19.7 41.0 63.7 145.4 219.3 33.6 32.1 52.4 36.9 49.4 42.5 49.5 NAIF1 "bA379C10.2, C9orf90, DKFZp762G199" ENSG00000171169 "Nuclear apoptosis inducing factor 1" Q69YI7 9 128061233-128068206 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054898, HPA064931" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA054898: AB_2682633, HPA064931: AB_2732725" "unprognostic (7.09e-2)" "unprognostic (5.92e-2)" "unprognostic (1.20e-2)" "unprognostic (5.56e-3)" "unprognostic (1.58e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.60e-1)" "unprognostic (6.15e-2)" "unprognostic (9.41e-2)" "prognostic favorable (1.02e-5)" "unprognostic (3.08e-1)" "prognostic favorable (8.30e-5)" "unprognostic (8.48e-2)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (3.92e-2)" 2.0 2.4 1.2 1.8 1.4 4.3 1.8 1.2 1.6 2.1 1.3 2.0 2.0 2.2 0.7 2.6 1.8 1.0 2.0 1.2 1.2 1.7 2.6 1.6 2.6 1.4 1.2 1.7 2.4 1.8 1.5 1.6 1.3 1.5 1.2 0.7 2.2 1.4 2.7 2.3 2.3 1.4 1.1 3.2 2.1 3.4 1.6 2.4 1.7 1.9 2.2 1.6 1.8 1.2 5.1 4.4 2.7 7.0 2.5 2.2 6.1 3.8 2.3 3.2 2.6 3.5 4.0 6.2 3.3 2.4 4.5 3.8 2.8 2.9 2.6 19.1 3.8 4.6 5.4 2.0 4.1 6.4 12.5 2.0 3.4 2.5 4.0 2.6 2.9 6.9 11.0 3.9 3.0 5.9 6.2 7.7 3.0 6.9 7.4 5.9 4.3 5.7 2.5 3.1 3.9 4.5 3.8 5.2 4.0 2.0 4.0 6.3 2.0 3.8 11.8 3.2 4.5 6.3 14.0 4.1 3.6 4.1 5.1 0.0 0.7 1.2 0.5 0.6 0.4 0.3 1.1 0.7 0.7 0.9 0.7 0.6 1.5 0.5 1.0 0.5 0.3 0.5 1.2 1.4 1.2 1.6 1.2 1.2 1.4 1.2 1.3 1.1 1.6 1.2 5.6 0.0 3.0 2.0 5.4 4.8 4.6 3.9 4.6 4.0 3.9 2.8 4.2 4.3 3.4 5.5 0.0 5.8 6.6 6.3 3.9 3.5 8.7 2.6 3.5 6.4 5.4 0.8 1.0 6.6 5.7 3.1 1.5 3.2 8.2 3.7 7.1 2.4 5.7 10.1 0.9 4.0 0.0 7.0 3.6 10.9 6.2 3.1 0.0 0.0 5.1 4.6 7.2 2.0 0.7 3.7 5.1 3.0 3.4 3.3 7.3 4.2 1.8 5.0 0.0 4.2 3.5 15.1 7.8 5.0 3.8 4.7 4.0 4.4 3.6 2.9 NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 63.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 597.2;Proximal tubular cells: 203.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 49.8;RPMI-8226: 73.4;SK-BR-3: 84.1" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 2300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: AB_2665644, CAB068207: AB_2665681, HPA023739: AB_1854308, HPA024017: AB_1854309" "unprognostic (7.08e-2)" "unprognostic (1.55e-1)" "unprognostic (5.76e-3)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (7.65e-2)" "unprognostic (2.19e-1)" "unprognostic (2.84e-1)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.02e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-2)" 15.7 13.6 4.1 6.3 4.7 21.9 14.6 3.9 8.7 15.8 4.6 22.2 61.4 9.7 1.7 37.1 10.6 5.8 10.8 4.3 4.8 15.7 63.1 13.8 6.6 5.4 4.1 9.6 12.4 5.0 6.0 5.4 4.0 11.3 3.9 0.2 29.2 10.5 10.1 27.9 47.3 2.9 4.4 19.4 22.5 10.5 4.7 4.1 9.8 4.6 5.2 13.2 18.1 5.6 14.8 7.2 0.6 1.4 3.2 2.0 4.0 0.7 7.5 4.5 1.7 5.6 34.3 1.8 7.8 0.5 0.0 25.6 1.8 34.6 0.4 4.3 12.1 16.7 25.5 1.9 42.5 2.1 14.8 3.2 16.6 0.3 0.0 0.1 18.1 32.9 21.5 8.8 0.1 11.1 6.7 8.0 5.6 49.8 4.2 13.8 0.3 73.4 16.0 2.0 7.4 0.9 9.1 84.1 30.7 0.6 2.1 20.3 3.8 0.9 10.1 8.0 2.9 0.8 0.8 3.1 1.8 41.8 16.1 6.9 11.4 14.1 2.9 12.7 1.9 2.0 4.4 1.9 6.7 1.3 1.3 2.4 10.6 0.8 23.0 6.9 1.9 5.8 4.1 4.7 3.9 8.7 4.3 4.8 5.4 4.1 4.0 4.4 4.7 5.6 50.6 35.3 23.1 7.5 16.2 0.0 64.9 0.0 24.5 12.1 18.3 14.7 10.0 54.3 9.3 75.4 18.8 48.8 21.8 88.0 68.4 62.7 44.2 18.5 26.0 32.7 10.9 63.8 3.8 54.3 74.8 20.6 100.9 26.8 7.6 21.7 49.6 117.4 80.6 16.8 3.2 70.4 0.0 89.7 0.0 59.8 32.0 55.0 0.0 7.5 108.9 23.7 28.8 1.5 2.8 111.7 124.6 21.8 12.7 44.2 597.2 203.7 1.5 13.4 13.1 15.8 16.5 41.7 16.0 35.9 0.0 56.2 17.2 29.7 100.9 73.9 NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435968-78574874 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" Cytosol "HPA026793: AB_1848833" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (5.73e-3)" "unprognostic (1.79e-3)" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (4.62e-3)" "prognostic favorable (1.39e-5)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.22e-6)" "unprognostic (8.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" 7.3 11.9 10.7 6.8 12.3 6.2 11.1 12.4 13.3 9.6 19.8 11.3 10.3 9.1 11.2 8.1 9.9 7.0 11.7 10.4 11.7 19.0 23.5 7.6 9.6 11.7 13.9 11.4 10.6 11.4 7.6 8.0 13.1 10.8 10.9 13.4 10.7 7.3 23.5 7.2 9.7 7.4 11.3 7.4 9.9 7.5 11.4 11.7 11.5 19.6 9.7 8.7 8.1 12.3 16.7 22.8 23.5 15.4 16.1 13.5 19.5 13.5 13.1 20.6 16.9 39.4 17.4 40.9 34.1 8.7 19.8 21.5 39.9 26.3 28.3 27.0 21.3 28.9 17.3 33.7 13.3 31.3 10.1 9.4 16.8 18.1 32.0 18.3 17.9 33.7 44.5 11.0 23.1 19.4 32.7 50.3 25.6 67.3 27.3 33.6 38.2 55.5 27.2 23.0 27.8 17.5 20.1 25.4 35.5 25.1 24.1 12.3 10.9 27.7 32.8 32.0 23.1 18.1 33.1 91.1 5.4 27.7 19.2 9.5 9.3 4.4 11.1 10.4 13.8 17.6 12.8 12.5 16.6 15.0 18.5 16.7 2.0 20.3 12.8 12.7 10.5 10.3 10.7 12.3 12.4 13.3 10.4 11.7 11.7 13.9 13.1 11.3 11.4 12.3 5.8 19.2 26.4 27.7 14.5 13.5 14.2 12.0 12.5 5.2 9.4 6.5 8.8 5.7 10.3 5.5 2.1 20.0 4.4 4.0 29.4 9.5 13.1 10.1 7.4 6.6 12.0 9.2 34.7 7.3 23.6 9.0 10.2 9.0 8.2 14.0 2.5 19.8 12.4 0.0 45.1 8.3 22.4 6.3 11.6 5.4 7.8 6.3 17.8 45.0 2.9 6.3 4.1 42.7 47.7 7.5 9.9 4.9 14.6 17.5 7.0 28.9 10.2 9.0 6.6 7.5 8.8 8.6 19.5 12.0 13.8 15.3 7.8 9.0 14.6 10.7 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NBAS NAG ENSG00000151779 "NBAS subunit of NRZ tethering complex" A2RRP1 2 15166914-15561334 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.8;Inhibitory neurons: 187.9;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 159.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036817 Approved Approved "Nuclear membrane,Nucleoli,Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nuclear membrane, Nucleoli" "HPA036817: AB_10670925" "unprognostic (1.72e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.80e-2)" "unprognostic (4.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (5.84e-5)" 16.8 21.0 37.4 7.2 38.8 16.1 15.9 37.7 42.7 18.8 35.7 22.7 8.2 18.4 13.7 17.2 18.8 8.1 38.3 37.2 36.3 19.9 21.6 15.8 9.4 37.0 35.2 22.5 34.4 16.3 29.6 10.1 38.7 19.0 10.5 13.4 15.4 10.4 30.5 21.8 20.1 11.8 34.4 21.1 24.5 41.2 37.2 14.5 17.4 17.7 9.1 19.7 16.5 38.1 10.5 13.7 14.8 10.7 37.8 41.5 15.2 19.1 20.8 14.5 14.6 13.8 15.0 13.4 4.3 29.3 15.1 12.5 16.5 23.9 17.2 13.5 10.4 51.3 11.5 38.8 38.8 13.4 25.1 27.3 18.9 19.2 32.8 30.2 30.4 18.7 40.6 15.0 22.4 13.0 11.2 30.1 12.8 17.1 12.8 11.7 26.0 16.2 30.5 14.0 8.7 14.2 16.2 13.4 25.2 18.3 9.4 12.0 26.6 18.5 11.2 13.5 13.9 22.1 20.3 18.7 33.1 15.5 16.8 1.5 4.4 2.5 5.7 3.1 6.7 4.1 4.2 7.3 4.0 3.4 4.2 4.3 0.8 7.2 7.5 4.5 5.3 2.9 37.4 38.8 37.7 42.7 37.2 36.3 37.0 35.2 38.7 34.4 37.2 38.1 16.1 19.2 13.8 96.6 15.1 7.4 9.3 11.9 12.0 17.3 11.7 9.4 32.3 17.2 13.8 18.4 29.2 11.5 15.1 9.4 0.0 11.1 39.3 22.2 21.3 14.6 7.3 38.7 217.8 14.0 13.1 13.4 20.9 14.8 38.6 30.2 8.9 9.1 9.0 13.5 187.9 14.8 10.2 6.9 8.0 61.9 11.5 11.6 5.4 106.8 18.4 12.5 9.2 159.3 159.2 8.6 9.5 16.6 27.2 9.2 39.3 8.5 26.0 25.5 0.0 24.7 16.3 33.7 22.4 12.9 11.2 10.4 19.9 70.0 12.5 7.6 NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.5;retina: 65.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1016.1;Inhibitory neurons: 953.0;Oligodendrocyte precursor cells: 466.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 33.1;SH-SY5Y: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA039730: AB_10794202, HPA040385: AB_10795523" "unprognostic (1.80e-2)" "unprognostic (2.90e-1)" "unprognostic (4.99e-2)" "unprognostic (3.89e-4)" "unprognostic (3.59e-1)" "unprognostic (2.04e-1)" "unprognostic (8.75e-2)" "unprognostic (6.95e-3)" "unprognostic (5.01e-1)" "unprognostic (7.43e-2)" "unprognostic (1.03e-3)" "unprognostic (2.45e-1)" "prognostic favorable (7.86e-8)" "unprognostic (2.28e-2)" "unprognostic (9.35e-2)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" 2.4 7.2 7.7 1.5 10.7 0.3 4.9 19.0 23.5 3.5 2.8 5.8 1.4 6.1 2.2 3.3 5.5 3.4 6.9 17.4 2.8 4.1 0.6 2.0 1.6 4.1 0.1 6.2 3.1 7.1 8.3 0.6 4.8 6.6 2.5 65.7 4.7 8.4 5.6 1.5 2.5 6.5 0.4 3.2 2.7 3.5 0.0 5.6 6.3 5.7 1.2 3.6 2.8 4.5 0.0 4.5 10.9 6.1 0.7 0.1 0.3 7.0 10.8 7.9 6.6 0.1 1.0 3.0 0.0 12.9 4.7 0.3 3.7 1.5 16.3 1.4 3.6 0.0 3.4 1.2 0.5 1.9 4.7 2.1 1.2 0.1 0.7 33.1 1.8 1.2 0.1 17.6 1.1 1.9 1.1 0.0 4.6 6.2 2.0 1.1 4.7 0.9 9.3 2.1 6.2 80.1 5.4 0.1 3.6 8.1 2.0 0.4 0.1 2.0 1.2 0.0 1.6 1.9 0.5 1.3 5.4 0.6 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 7.7 10.7 19.0 23.5 17.4 2.8 4.1 0.1 4.8 0.4 0.0 4.5 19.7 28.9 9.2 132.9 5.2 1.0 5.3 2.7 1.2 124.8 5.0 6.5 51.8 11.5 14.1 9.2 146.0 0.1 4.4 0.3 1.9 9.2 19.3 5.6 18.4 10.1 22.9 0.8 1016.1 1.8 0.1 12.3 2.0 0.6 25.2 20.7 11.0 0.3 0.9 47.1 953.0 2.1 6.1 3.5 3.9 13.6 17.7 3.5 7.2 150.9 1.2 69.1 0.0 466.9 163.7 2.3 0.1 19.2 5.8 8.5 0.2 7.6 56.5 87.0 6.6 22.2 13.1 8.5 8.0 0.3 0.9 0.0 1.2 11.9 1.1 13.5 NBR1 "1A1-3B, CA125, KIAA0049, M17S2" ENSG00000188554 "NBR1 autophagy cargo receptor" Q14596 17 43170481-43211689 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 276.9;Late spermatids: 909.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022944, HPA022999, HPA023999" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nuclear bodies" "HPA022944: AB_2671001, HPA022999: AB_1859532, HPA023999: AB_1859533" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (3.26e-2)" "unprognostic (3.28e-2)" "unprognostic (3.27e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (2.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "prognostic favorable (2.00e-5)" "unprognostic (1.65e-1)" "unprognostic (4.88e-2)" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" 45.7 52.3 48.4 39.4 54.5 20.1 55.9 52.1 48.2 52.0 51.2 66.2 70.1 48.9 39.9 40.3 53.4 44.5 67.3 43.7 49.9 84.7 91.3 47.3 41.0 52.2 50.4 69.7 43.9 97.1 28.8 60.1 52.9 64.7 70.4 80.1 49.4 52.0 112.2 42.9 73.8 49.3 52.1 53.0 52.6 141.0 51.6 59.0 68.2 116.0 45.4 47.3 34.5 65.2 42.3 49.8 42.6 44.6 93.5 95.2 41.0 77.1 147.2 60.5 50.4 26.6 65.1 22.7 77.8 105.1 62.6 46.1 48.5 97.4 90.3 70.0 51.2 27.1 62.0 60.0 89.4 23.2 40.1 108.4 111.6 67.2 133.7 127.3 96.0 50.8 58.1 58.7 83.7 23.9 48.9 17.7 13.6 50.0 32.8 16.5 65.6 73.3 81.6 48.0 25.9 45.8 53.1 26.1 79.8 70.7 70.7 38.0 82.2 89.9 34.1 42.7 31.5 69.9 61.8 29.1 61.8 31.5 63.6 41.6 25.7 40.1 20.3 23.3 20.7 13.7 18.1 19.6 19.3 9.4 17.0 16.6 34.4 24.3 36.4 12.0 26.4 25.0 48.4 54.5 52.1 48.2 43.7 49.9 52.2 50.4 52.9 52.1 51.6 65.2 36.9 41.7 44.1 24.5 21.9 23.8 29.2 28.1 54.1 37.3 33.8 27.4 86.4 35.8 40.4 36.8 39.6 28.0 34.6 94.2 19.6 25.4 276.9 40.5 30.4 39.0 40.2 53.2 24.7 21.9 19.4 37.6 31.1 33.0 25.9 53.1 45.3 67.8 22.0 20.2 28.2 56.4 20.3 62.9 19.9 909.9 58.7 35.7 26.6 29.0 35.6 49.3 44.3 33.2 41.4 25.8 64.5 44.4 26.1 41.1 100.3 57.4 63.4 56.9 39.5 33.9 36.2 49.6 30.9 26.7 27.3 15.7 31.9 68.6 52.4 38.7 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: AB_670270, HPA023981: AB_1854688, HPA071110: " "unprognostic (1.91e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.63e-2)" "unprognostic (2.72e-3)" "prognostic unfavorable (1.41e-6)" "unprognostic (3.74e-2)" "unprognostic (4.31e-3)" "unprognostic (9.78e-2)" "unprognostic (6.70e-3)" "unprognostic (6.07e-2)" "unprognostic (1.66e-2)" "unprognostic (2.57e-2)" "unprognostic (9.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-2)" 212.0 192.8 128.8 226.0 146.3 301.4 228.7 129.1 139.6 180.0 114.1 183.6 160.7 205.2 150.2 228.8 173.2 132.2 164.3 115.9 152.3 166.2 218.5 147.4 289.7 148.8 141.5 258.2 209.0 258.9 115.9 203.4 140.4 155.4 219.2 147.1 157.0 160.9 350.9 197.1 157.4 201.0 137.9 176.3 164.7 126.2 142.1 347.0 198.4 228.2 329.0 271.1 169.1 143.9 718.3 691.8 715.7 640.1 485.7 592.0 823.0 790.4 497.2 690.8 628.2 1227.4 521.4 1083.7 608.6 651.0 892.6 719.5 1614.4 1059.9 1284.7 554.6 644.0 1587.3 605.9 1749.5 544.0 1930.4 632.7 513.5 613.2 872.3 1019.6 394.9 834.2 770.5 1745.4 378.6 760.5 1176.4 1443.2 1086.7 1202.0 728.7 435.9 1290.8 1452.0 918.4 583.8 959.9 749.0 502.0 555.8 704.5 706.9 625.7 476.8 985.3 686.3 611.4 626.7 714.5 1063.7 624.3 554.5 1885.9 467.2 1173.1 685.2 27.3 95.6 62.5 136.5 100.3 152.8 113.5 118.4 121.9 130.6 111.9 130.3 114.2 16.8 177.8 121.7 102.0 102.3 151.0 128.8 146.3 129.1 139.6 115.9 152.3 148.8 141.5 140.4 137.9 142.1 143.9 286.2 291.7 411.7 8.1 468.9 459.9 633.8 241.0 644.9 145.0 315.2 303.8 320.9 147.3 401.6 195.0 47.9 386.9 596.2 215.0 230.9 294.4 20.6 348.7 669.8 291.1 200.0 419.2 9.3 254.4 444.6 370.9 292.0 421.8 451.7 262.7 130.6 242.0 239.5 80.8 10.4 319.6 156.6 133.7 231.1 32.2 217.2 281.8 165.4 10.3 268.9 199.6 346.1 14.1 14.9 268.0 153.9 159.9 543.5 651.1 120.1 277.6 250.3 141.0 151.2 548.9 442.0 433.3 532.4 707.9 441.4 379.0 454.0 442.6 380.6 449.1 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 467.5;Excitatory neurons: 313.0;Inhibitory neurons: 421.8;Microglial cells: 341.9;Oligodendrocyte precursor cells: 459.4;Oligodendrocytes: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 16.6 15.1 24.0 13.3 25.4 17.3 17.3 24.6 28.2 18.6 13.6 15.9 20.9 19.0 12.8 17.6 15.7 14.0 15.3 29.6 19.5 18.9 15.0 16.0 15.3 17.7 19.2 26.6 17.4 30.0 16.6 17.1 16.0 15.2 16.6 47.3 16.0 20.2 33.4 15.7 18.9 19.0 19.5 16.3 12.5 19.9 21.8 26.1 11.8 36.1 16.3 14.9 15.5 22.3 14.1 10.3 17.7 9.2 19.2 17.3 26.9 7.4 14.7 9.1 8.1 9.6 5.9 10.2 3.1 13.5 17.4 3.4 10.7 6.3 9.8 48.6 15.5 36.5 4.1 4.1 12.0 16.9 29.1 27.9 9.4 8.8 7.1 11.3 9.4 12.9 22.6 16.5 14.0 9.4 15.1 6.0 8.5 8.2 6.8 11.8 81.5 5.1 9.9 18.9 16.2 12.8 17.1 10.2 7.4 9.3 12.3 8.6 10.2 15.2 11.9 10.5 7.5 18.8 17.5 17.2 8.6 10.5 7.7 10.6 3.3 7.0 3.4 2.6 3.8 1.6 3.0 3.8 2.5 2.4 2.9 3.5 13.8 3.5 2.9 5.2 3.7 2.0 24.0 25.4 24.6 28.2 29.6 19.5 17.7 19.2 16.0 19.5 21.8 22.3 41.0 38.5 31.5 467.5 16.7 30.5 11.6 7.8 14.2 96.5 32.3 26.7 41.9 17.2 22.8 14.7 52.1 13.1 47.0 39.0 7.9 16.5 29.7 14.6 37.6 34.9 25.2 29.9 313.0 26.6 18.1 39.8 19.9 28.4 20.2 52.9 36.8 22.8 17.9 62.2 421.8 20.7 20.3 29.8 30.3 7.4 47.2 37.7 19.6 341.9 34.7 66.7 78.2 459.4 305.8 20.1 33.5 43.2 14.3 15.7 30.4 12.5 16.9 71.6 39.5 116.9 34.4 37.7 37.6 16.6 31.0 5.3 33.4 27.2 24.1 21.7 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 476.2;Macrophages: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 117.1 67.8 45.6 91.5 52.5 189.5 96.9 56.1 50.9 85.1 50.7 110.3 249.7 70.2 74.6 110.3 62.6 87.8 156.8 40.6 55.8 159.7 372.9 108.3 102.6 52.4 53.5 65.5 64.6 97.9 25.2 131.3 53.6 132.2 115.7 33.7 79.2 78.7 163.5 71.1 155.9 98.3 52.6 148.1 90.3 43.6 51.6 124.4 87.0 193.6 150.3 104.6 46.8 60.0 142.7 58.5 68.0 70.4 176.9 159.4 170.3 128.3 204.8 122.1 119.6 91.0 102.3 161.2 149.2 211.2 69.1 141.8 72.6 142.3 137.1 114.4 74.1 108.4 74.3 263.5 124.0 279.9 229.7 156.1 139.2 104.2 175.7 131.6 185.5 79.5 119.7 93.5 171.9 64.0 136.1 104.3 41.4 110.2 34.8 79.5 99.3 96.7 148.9 119.4 68.2 46.1 128.9 146.2 131.5 133.5 105.7 135.3 171.6 75.8 89.9 81.3 87.5 69.3 79.1 156.9 94.6 231.2 41.2 692.1 363.6 611.8 78.9 223.6 86.2 57.6 73.3 74.9 251.9 53.8 78.2 66.4 839.6 119.0 275.3 77.4 92.8 559.4 45.6 52.5 56.1 50.9 40.6 55.8 52.4 53.5 53.6 52.6 51.6 60.0 44.5 51.3 95.2 13.4 44.6 49.5 39.3 126.2 50.7 14.3 49.6 38.5 161.3 45.8 96.2 44.1 29.2 104.7 58.2 108.8 80.3 45.3 105.4 45.1 37.7 52.9 26.9 476.2 17.4 51.8 107.2 45.3 42.3 56.9 195.2 28.2 55.3 166.7 181.4 20.2 20.5 45.4 59.0 254.5 74.2 72.4 37.3 316.1 51.6 16.9 158.4 38.2 44.3 18.6 22.9 47.8 63.9 47.4 37.6 62.0 162.5 128.8 59.7 13.0 13.1 36.7 46.7 24.5 16.5 71.9 56.7 158.2 41.3 60.7 71.3 52.0 NCOA7 "dJ187J11.3, ERAP140, TLDC4" ENSG00000111912 "Nuclear receptor coactivator 7" Q8NI08 6 125781161-125932034 "Predicted intracellular proteins, Transporters" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 709.7;Squamous epithelial cells: 515.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030289, HPA030290, HPA030291, HPA030292" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA030289: AB_10670031, HPA030290: AB_10601971, HPA030291: AB_10669597, HPA030292: AB_10670834" "unprognostic (1.01e-2)" "unprognostic (3.21e-2)" "unprognostic (7.32e-3)" "unprognostic (7.27e-3)" "unprognostic (1.54e-1)" "unprognostic (4.67e-2)" "unprognostic (1.26e-1)" "unprognostic (6.27e-2)" "unprognostic (2.73e-1)" "unprognostic (2.14e-1)" "unprognostic (6.08e-2)" "unprognostic (4.37e-2)" "prognostic favorable (1.78e-6)" "unprognostic (2.10e-1)" "unprognostic (2.58e-1)" "unprognostic (1.14e-1)" "unprognostic (8.10e-2)" 53.9 60.4 19.5 45.8 30.6 42.7 27.4 21.4 50.2 29.0 0.0 30.1 33.0 22.3 5.2 30.4 15.9 46.6 16.0 28.2 23.9 56.6 32.9 52.1 30.1 47.5 12.3 14.8 19.9 8.8 29.7 12.9 45.0 18.6 29.2 18.2 38.2 12.9 6.9 11.1 39.2 28.3 10.6 24.4 30.8 7.8 19.0 21.7 25.1 9.2 28.5 101.8 19.7 48.3 13.7 36.6 2.2 16.0 78.2 46.3 23.7 18.2 71.9 22.1 30.1 34.3 12.7 55.2 96.5 10.0 108.0 78.7 12.6 12.4 13.3 120.2 16.5 28.0 43.7 12.3 44.5 16.4 25.4 33.3 29.4 21.1 16.3 39.1 46.7 18.0 38.7 30.6 13.9 13.7 16.1 16.2 2.7 33.8 7.6 12.3 5.7 10.3 39.1 90.4 36.9 33.5 93.7 22.6 42.1 6.5 3.8 19.3 27.7 5.1 10.9 26.3 14.1 39.9 34.1 28.8 11.5 21.2 18.7 17.0 11.4 4.0 19.2 9.1 24.1 17.7 18.1 15.6 10.0 11.1 9.6 9.4 6.4 13.6 14.2 34.1 8.1 5.1 19.5 30.6 21.4 50.2 28.2 23.9 47.5 12.3 45.0 10.6 19.0 48.3 144.6 314.1 371.9 27.7 33.7 98.1 270.8 311.2 709.7 50.2 94.2 47.9 11.4 98.7 324.1 62.5 43.8 9.3 84.6 113.2 80.3 241.7 0.9 160.1 90.2 130.2 35.8 29.8 144.9 139.2 8.9 94.8 142.8 298.2 37.3 18.5 106.7 23.2 13.6 37.0 89.5 119.3 288.9 33.8 57.4 6.8 42.3 41.9 51.6 75.9 33.4 76.8 59.8 34.2 303.9 108.7 160.1 29.3 44.1 129.5 24.3 103.2 335.8 53.3 13.1 33.8 49.3 11.2 33.9 515.9 59.2 3.8 63.5 36.5 130.6 294.4 NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" 5.4 5.2 3.4 9.5 3.5 8.4 11.1 3.6 4.1 5.7 3.6 11.9 8.9 6.5 7.4 7.7 7.5 4.6 4.5 3.6 3.4 6.9 7.8 4.7 15.7 3.2 3.3 5.9 4.7 9.5 1.7 8.0 3.3 4.8 14.2 6.0 4.2 5.2 4.3 7.3 8.2 7.1 3.5 5.6 6.4 7.5 3.5 14.2 6.8 5.2 18.4 7.1 4.2 3.9 61.6 31.2 42.8 43.7 15.5 15.5 49.3 40.9 31.0 63.8 51.1 47.5 40.4 119.0 26.2 18.6 51.2 72.0 73.2 43.3 89.8 29.8 50.9 58.5 42.9 40.5 14.3 95.3 31.9 9.4 17.0 62.9 37.5 18.6 39.1 44.2 67.7 16.9 35.6 22.2 47.2 38.2 101.0 52.2 49.9 52.0 68.4 66.0 29.8 41.7 25.4 32.2 36.5 71.5 35.9 45.3 55.3 50.2 22.7 32.9 32.6 45.5 74.9 17.9 48.8 84.7 27.3 71.6 42.2 0.0 2.3 1.5 3.0 5.0 4.7 3.6 2.8 2.7 2.6 2.8 5.3 4.1 0.1 3.1 3.3 2.3 3.4 2.4 3.4 3.5 3.6 4.1 3.6 3.4 3.2 3.3 3.3 3.5 3.5 3.9 4.4 6.4 6.3 12.4 8.7 10.1 6.4 9.0 12.0 4.5 10.1 6.3 8.1 4.3 5.4 5.5 2.1 11.5 5.9 7.9 0.0 8.5 2.3 5.0 5.6 6.1 0.0 19.4 13.8 9.1 20.2 6.3 8.6 4.6 7.6 21.5 5.3 7.1 11.8 3.3 11.0 10.3 16.2 8.2 8.9 2.1 2.8 7.1 7.2 13.1 4.7 3.3 3.1 11.6 19.4 7.0 5.8 3.4 20.1 8.9 2.9 4.5 5.5 2.9 6.6 6.3 15.7 11.8 14.3 18.2 8.5 6.8 6.7 4.3 18.2 6.5 NDOR1 "bA350O14.9, CIAE1, NR1" ENSG00000188566 "NADPH dependent diflavin oxidoreductase 1" Q9UHB4 9 137205685-137217009 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Oligodendrocytes: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024504 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Intermediate filaments" "HPA024504: AB_1854338" "unprognostic (1.67e-1)" "unprognostic (1.44e-2)" "unprognostic (3.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (5.89e-3)" "unprognostic (5.99e-2)" "unprognostic (9.30e-2)" "unprognostic (3.00e-1)" "unprognostic (2.61e-3)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" "unprognostic (4.69e-3)" "unprognostic (2.05e-1)" "unprognostic (4.30e-2)" "unprognostic (6.74e-3)" 6.5 8.2 8.7 9.8 9.6 17.2 6.9 7.9 12.5 8.1 5.4 8.4 9.6 7.8 2.0 8.3 7.9 4.6 6.6 8.3 7.1 9.0 7.1 8.6 11.5 10.7 9.0 7.0 8.9 4.0 8.2 4.0 10.2 9.6 2.9 3.9 8.6 5.2 4.0 9.5 10.6 3.7 7.9 14.2 8.7 10.5 9.9 8.9 10.1 1.5 5.4 7.8 7.2 12.9 14.2 21.2 13.8 21.8 5.7 5.6 42.7 20.4 9.1 19.1 13.0 21.6 16.3 19.9 15.6 7.7 15.3 52.1 10.0 14.3 3.8 25.9 16.3 17.6 59.7 11.6 9.6 19.9 36.2 7.8 9.7 21.6 7.9 5.3 8.9 25.9 29.2 20.6 7.0 25.8 21.0 35.8 22.5 12.9 26.0 38.0 16.5 28.2 6.0 12.4 17.6 17.5 16.8 17.0 10.6 6.1 27.2 22.8 12.0 35.3 22.9 41.7 23.2 12.5 26.8 20.7 15.4 18.1 20.7 1.1 2.1 3.1 1.3 2.2 1.1 0.5 1.2 1.2 1.7 1.0 0.6 0.6 2.9 0.7 1.7 1.1 1.8 1.5 8.7 9.6 7.9 12.5 8.3 7.1 10.7 9.0 10.2 7.9 9.9 12.9 1.4 0.0 2.6 13.4 3.9 0.5 0.7 1.0 5.2 0.4 1.5 1.3 1.6 1.5 1.6 3.7 0.0 4.5 1.4 3.3 1.9 1.1 0.8 1.3 1.9 1.8 2.4 1.3 8.6 1.1 3.5 1.6 5.1 2.1 1.3 2.0 1.1 0.8 2.5 0.0 7.5 1.9 2.0 3.2 1.3 1.1 0.6 2.7 1.8 6.5 5.4 0.1 5.2 3.5 10.5 1.6 1.5 0.4 6.9 0.7 2.6 1.2 0.3 0.9 0.0 0.9 1.4 1.9 1.2 3.2 0.3 3.7 3.8 1.6 2.2 0.8 NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;ovary: 46.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 181.3;Muller glia cells: 105.5" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-87 MG: 72.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" 0.5 0.0 31.5 0.0 33.4 0.0 3.3 30.9 35.8 20.9 22.4 0.2 0.1 15.4 22.0 0.0 20.8 0.4 0.3 31.5 29.6 0.1 0.0 0.0 0.2 30.1 33.2 46.2 0.0 0.2 0.1 4.0 31.6 7.1 0.2 19.2 0.1 13.1 0.0 0.6 0.2 11.4 32.4 0.1 0.3 1.0 34.2 0.0 0.2 0.0 0.2 0.5 2.3 32.4 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 1.8 0.0 4.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.0 0.0 72.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 33.4 30.9 35.8 31.5 29.6 30.1 33.2 31.6 32.4 34.2 32.4 0.0 0.0 0.0 29.0 0.0 0.1 0.0 1.2 0.0 0.6 1.3 0.1 0.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 9.1 17.7 0.2 0.0 0.0 4.2 0.0 0.3 0.9 0.0 17.0 0.0 181.3 0.0 0.0 0.1 0.0 0.8 0.0 2.0 0.0 0.0 0.7 13.4 0.6 0.0 0.0 0.0 105.5 0.0 1.5 9.5 1.2 0.0 9.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 5.4 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1885.3;salivary gland: 2081.6;skeletal muscle: 1828.7" "Cell type enhanced" "Detected in many" "Astrocytes: 379.0;Distal tubular cells: 485.2;Muller glia cells: 548.0;Sertoli cells: 598.2" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.4" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.4" "Cell line enhanced" "Detected in many" "Hep G2: 57.0;HMC-1: 39.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" 192.0 400.6 1613.1 27.4 1885.3 2.8 321.6 1623.2 1666.4 395.4 1189.8 198.3 72.1 229.7 260.3 229.5 305.0 130.7 327.2 1551.7 1590.0 150.1 544.4 115.5 48.6 1690.6 1686.1 476.1 93.7 278.5 88.5 45.3 1581.9 171.3 111.0 134.1 2081.6 208.0 1828.7 220.3 125.4 127.7 1584.5 152.0 130.9 33.3 1752.7 40.1 99.9 1591.4 100.4 158.0 265.8 1597.9 10.9 2.3 6.8 12.6 1.1 0.0 1.0 0.2 4.5 3.9 2.2 15.1 20.0 0.6 4.0 0.3 6.2 17.6 30.3 6.3 5.4 0.1 10.9 14.3 2.2 57.0 1.3 1.3 39.0 11.8 13.1 0.9 1.9 6.3 0.0 12.6 29.0 1.2 0.6 9.4 5.0 4.0 17.9 35.2 0.8 14.6 0.7 3.7 7.6 27.4 0.1 19.4 3.0 3.3 14.4 17.3 26.6 8.2 0.0 1.2 20.8 0.4 0.4 6.1 4.8 0.3 1.8 0.3 4.7 0.0 6.5 0.7 8.3 1.5 11.4 6.4 12.6 11.9 204.4 4.4 18.7 14.0 1.4 3.0 0.1 7.0 9.4 15.3 1613.1 1885.3 1623.2 1666.4 1551.7 1590.0 1690.6 1686.1 1581.9 1584.5 1752.7 1597.9 98.0 0.0 11.9 379.0 6.7 28.7 83.7 86.4 12.0 6.3 240.7 201.2 180.2 151.5 110.9 40.5 10.4 11.5 9.1 81.4 485.2 104.9 6.3 33.3 11.0 53.9 33.5 8.4 1.1 21.7 0.7 62.3 18.8 40.2 48.8 79.0 164.2 214.9 20.7 3.3 3.9 77.4 57.0 30.8 137.6 14.4 348.6 30.4 321.9 47.8 8.7 548.0 1.0 42.7 71.0 16.3 37.9 166.3 1.2 68.5 18.5 41.3 70.8 15.5 598.2 167.7 162.8 1.7 5.5 21.6 30.4 21.6 11.9 66.8 118.9 155.9 NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 945.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1493.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Nuclear membrane" "HPA051739: AB_2681585, HPA064441: " "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.95e-2)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" "unprognostic (9.66e-3)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (3.69e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "prognostic favorable (1.79e-4)" 148.6 338.4 159.7 90.3 169.1 112.4 145.1 175.9 203.2 126.2 173.2 170.0 147.8 117.9 133.8 159.5 113.0 85.7 619.5 163.5 178.4 232.4 187.4 102.9 93.8 168.3 163.0 119.8 137.4 260.3 170.2 76.8 168.6 118.1 148.7 100.2 148.4 117.4 945.3 144.5 135.6 103.4 170.7 112.1 162.3 106.5 161.7 125.6 113.1 562.2 114.2 133.5 142.1 172.8 294.8 204.3 246.7 248.5 151.0 181.4 199.2 157.0 212.1 205.4 224.5 200.9 219.8 147.8 311.6 177.8 255.6 272.5 191.3 202.7 155.7 227.5 212.6 226.1 205.7 208.1 90.4 202.7 256.8 161.3 268.5 98.9 125.8 246.0 258.5 271.7 138.5 219.2 220.9 224.1 398.6 294.8 193.9 478.9 554.7 228.8 141.0 325.8 337.3 177.9 273.8 283.4 186.5 205.7 360.0 162.0 348.0 319.9 199.8 179.0 233.2 76.9 226.5 263.2 260.1 454.3 283.6 279.8 250.8 205.0 164.8 197.2 156.0 229.5 162.2 231.6 215.2 176.8 213.9 176.3 182.2 181.8 101.6 152.7 238.2 267.9 300.6 205.7 159.7 169.1 175.9 203.2 163.5 178.4 168.3 163.0 168.6 170.7 161.7 172.8 274.1 163.5 162.6 36.9 167.0 222.3 289.0 612.6 190.6 137.8 290.1 351.3 1493.1 311.7 348.3 320.0 58.4 366.0 158.1 472.4 1226.7 556.7 999.2 259.9 188.9 235.7 298.7 196.9 22.6 620.9 421.0 213.7 175.3 293.5 174.8 139.4 183.5 513.9 330.3 84.1 22.0 526.3 451.6 240.2 247.9 164.6 275.2 196.2 434.0 15.9 339.2 340.7 186.4 13.0 31.2 567.9 581.8 277.2 283.2 243.2 613.4 1225.1 266.2 168.4 256.4 208.1 259.0 418.9 87.5 288.4 251.5 352.4 168.1 271.3 462.8 344.0 NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 606.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" 97.4 171.6 94.3 69.2 97.4 149.8 101.7 106.8 139.7 63.9 106.0 124.2 102.3 69.7 91.1 142.6 64.0 68.7 419.3 96.7 106.0 180.7 404.2 88.6 105.0 105.9 104.4 52.4 111.6 136.7 72.1 73.7 105.9 88.5 119.8 129.9 97.4 72.4 606.9 94.7 100.5 80.6 103.7 86.4 133.8 79.6 102.7 90.2 72.7 538.3 105.1 122.1 76.5 104.6 136.5 139.8 159.1 148.4 116.6 164.0 133.4 165.4 266.5 217.7 205.5 265.1 109.4 209.4 149.5 158.6 200.3 66.9 157.5 175.5 208.8 104.6 136.6 133.0 135.3 364.8 133.6 373.8 159.2 139.2 144.3 134.9 146.2 156.8 239.3 184.3 216.5 644.0 204.6 171.6 263.5 328.9 131.4 750.5 172.3 124.5 118.2 794.2 354.3 218.7 167.0 122.3 164.6 188.0 220.3 113.6 174.2 282.8 145.8 273.4 194.3 198.8 223.0 180.4 292.3 237.1 195.4 166.0 181.0 250.8 161.8 194.2 118.1 196.1 148.3 237.6 176.9 140.5 237.9 201.1 153.5 142.7 76.0 124.2 187.9 315.1 231.9 231.8 94.3 97.4 106.8 139.7 96.7 106.0 105.9 104.4 105.9 103.7 102.7 104.6 107.3 80.1 145.8 17.6 143.1 148.0 319.0 629.4 159.4 101.2 165.0 167.3 69.9 178.7 339.5 150.8 87.6 344.1 146.6 211.0 876.5 415.2 271.5 160.3 108.2 117.3 106.5 165.4 32.9 531.4 323.3 122.0 144.3 183.9 120.3 109.7 96.4 351.5 313.5 94.2 37.3 201.7 480.1 115.7 267.1 186.2 122.1 170.2 231.3 17.8 293.2 167.1 96.8 32.2 46.5 530.3 201.2 102.0 244.9 554.3 349.9 810.6 293.4 184.2 105.2 124.0 196.3 217.4 175.0 226.5 147.6 289.4 165.7 266.7 227.3 469.0 NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 323.2;Alveolar cells type 1: 471.1;Glandular and luminal cells: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 137.3;HSkMC: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009720: , HPA009689: , HPA038768: AB_2676196, HPA039270: AB_2676422, HPA072955: " "unprognostic (2.83e-3)" "unprognostic (2.33e-2)" "unprognostic (1.08e-2)" "unprognostic (6.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (3.05e-2)" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (2.25e-2)" "unprognostic (2.37e-1)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" 94.7 8.6 8.3 23.3 8.1 8.6 64.2 6.4 12.3 26.6 14.4 30.7 15.5 19.2 17.5 14.5 22.7 31.4 32.7 7.7 6.4 33.8 20.7 91.9 25.8 8.3 7.3 8.3 17.1 9.5 8.1 69.2 8.5 22.4 30.2 9.8 26.7 29.8 27.2 20.6 38.1 25.8 7.4 25.2 23.5 6.9 9.7 22.2 25.6 12.0 22.2 34.5 15.3 7.9 4.4 29.0 26.4 0.4 17.7 2.3 27.7 6.6 8.2 12.2 22.4 9.3 1.9 9.2 137.3 14.7 1.5 12.6 36.0 13.5 15.8 4.1 1.0 0.8 4.4 62.3 8.3 10.1 0.4 67.7 4.0 7.9 1.3 4.4 21.0 0.8 0.1 7.6 27.7 1.3 5.8 4.0 4.1 34.6 2.9 1.6 0.7 5.4 6.1 39.8 0.6 4.8 1.1 31.2 55.5 29.3 2.3 7.7 53.8 8.2 14.3 0.8 16.5 7.8 34.8 11.4 0.2 7.9 36.6 24.2 13.3 37.3 18.3 28.5 14.7 10.9 12.2 17.5 14.1 12.3 6.4 9.9 80.9 12.3 50.6 8.7 12.1 17.1 8.3 8.1 6.4 12.3 7.7 6.4 8.3 7.3 8.5 7.4 9.7 7.9 323.2 471.1 135.1 11.1 34.9 60.5 235.6 83.5 98.4 4.7 43.1 38.0 14.2 50.1 89.0 44.1 25.0 56.3 45.9 103.4 9.8 62.0 8.2 244.8 24.8 148.1 108.3 2.5 18.2 19.8 42.6 37.2 107.6 337.0 64.5 15.7 86.7 21.6 14.7 10.1 11.3 108.4 12.2 29.8 28.9 4.3 7.5 51.4 24.9 34.7 15.4 84.1 64.9 8.0 4.9 69.1 43.6 29.0 34.8 66.1 100.5 26.7 64.4 12.4 26.3 8.8 30.0 2.1 1.1 11.4 20.6 42.8 59.4 37.2 46.6 90.3 NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 675.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 32.7;Distal tubular cells: 103.7;Enteroendocrine cells: 33.3;Excitatory neurons: 64.6;Horizontal cells: 30.3;Rod photoreceptor cells: 110.0" "Cancer enhanced" "Detected in many" "renal cancer: 24.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Group enriched" "Detected in some" 4 "HEK 293: 456.2;PC-3: 145.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 200000 "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: AB_1854397, HPA015021: AB_2669135" "unprognostic (7.63e-2)" "unprognostic (1.36e-2)" "unprognostic (9.53e-2)" "unprognostic (6.81e-2)" "unprognostic (2.82e-2)" "unprognostic (6.69e-2)" "unprognostic (3.69e-2)" "unprognostic (3.78e-3)" "unprognostic (3.06e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.91e-4)" "unprognostic (5.76e-3)" "unprognostic (7.88e-2)" "unprognostic (3.97e-3)" "unprognostic (3.17e-3)" 0.1 18.0 35.4 1.3 36.7 0.0 0.0 103.6 675.9 2.0 0.0 2.5 0.6 0.1 0.3 5.4 1.3 0.1 0.1 50.9 75.6 5.0 0.0 0.0 0.1 425.7 41.1 0.2 0.2 0.1 4.0 0.0 231.3 1.8 1.5 89.5 0.0 15.6 0.0 0.9 1.9 1.1 33.9 0.2 0.8 1.7 216.1 12.7 0.7 0.1 0.3 0.0 1.4 184.0 0.0 0.6 68.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.6 0.0 0.0 456.2 0.0 0.0 0.0 21.6 0.0 1.0 8.3 2.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 18.8 0.0 145.4 0.0 0.0 0.0 31.7 4.2 30.9 31.6 11.2 0.0 1.9 2.2 0.0 0.0 0.0 2.2 31.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 1.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.2 1.5 35.4 36.7 103.6 675.9 50.9 75.6 425.7 41.1 231.3 33.9 216.1 184.0 0.1 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.6 32.7 0.0 0.0 3.2 0.0 0.0 0.0 8.4 0.0 0.1 0.1 103.7 0.1 0.4 0.1 0.3 3.7 33.3 0.0 64.6 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 30.3 29.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 27.2 0.1 27.8 0.0 14.6 18.4 0.0 0.1 9.4 0.0 0.0 0.0 0.2 0.0 110.0 0.0 0.1 0.2 0.0 13.2 1.5 0.0 0.0 1.6 1.4 0.0 0.0 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392809-169612627 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 126.3;Inhibitory neurons: 170.5;Oligodendrocytes: 196.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 6.0 6.1 5.1 4.9 6.8 4.2 5.2 7.1 5.3 7.6 2.7 4.0 3.2 7.3 2.8 4.6 9.3 6.1 6.9 3.5 8.8 5.9 4.2 4.6 5.3 7.5 7.7 9.4 4.0 6.5 2.9 4.3 7.6 6.7 4.4 8.7 4.2 6.0 3.3 2.3 3.5 6.6 7.6 5.1 4.9 11.8 5.3 6.8 7.9 4.6 4.6 5.6 2.8 7.7 5.8 2.5 10.0 11.0 15.5 17.1 3.3 11.9 10.6 9.3 8.8 3.3 6.7 15.4 2.2 10.4 9.0 1.9 9.7 10.1 10.5 16.9 6.5 10.3 10.4 3.9 9.0 10.6 7.9 13.7 5.9 9.5 16.7 19.1 9.3 14.5 18.6 28.2 12.1 3.7 13.6 4.6 3.3 3.6 6.0 8.4 6.5 4.9 9.7 6.8 11.0 12.5 8.6 4.2 8.1 7.7 5.3 4.6 11.2 6.0 5.4 6.2 8.1 11.3 18.6 11.6 9.7 5.1 10.7 5.1 0.9 0.9 1.9 1.5 2.2 2.0 1.5 1.2 0.7 2.0 2.2 2.3 0.6 1.1 0.7 1.6 1.6 0.7 5.1 6.8 7.1 5.3 3.5 8.8 7.5 7.7 7.6 7.6 5.3 7.7 12.2 12.8 16.4 162.6 34.2 9.6 15.8 12.1 21.1 21.8 11.3 12.7 37.2 4.3 17.8 18.4 29.2 20.8 17.0 6.4 17.6 10.4 109.7 67.2 21.6 13.2 7.2 26.7 126.3 6.2 8.6 25.0 17.3 23.7 18.3 20.1 9.7 7.8 10.7 18.5 170.5 5.6 20.3 7.0 7.4 48.2 23.6 14.5 5.4 53.4 6.6 26.1 15.5 115.1 196.1 8.9 4.0 31.6 23.2 6.9 5.3 9.6 68.4 24.9 13.1 32.8 25.5 67.9 37.3 21.3 6.3 29.6 22.0 26.0 6.3 9.2 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 121.0;Hofbauer cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 18.0 6.1 33.5 32.6 34.3 19.6 14.7 28.1 32.4 26.1 26.5 22.3 17.5 12.2 3.4 8.5 11.2 25.4 7.4 31.8 37.0 17.2 68.2 24.3 27.4 49.8 41.2 9.0 16.7 1.9 6.1 30.2 33.9 19.6 22.5 11.3 20.6 16.7 8.2 5.4 25.8 18.7 34.4 16.6 27.1 7.8 44.2 10.2 7.3 3.1 31.7 24.3 6.4 30.4 31.8 50.0 47.8 18.8 88.3 113.9 59.3 38.8 61.1 58.4 48.4 47.7 57.0 38.2 61.0 74.6 133.2 5.9 24.7 111.7 39.4 43.7 21.8 104.4 42.1 85.4 105.2 19.4 250.0 152.8 17.8 55.4 56.9 152.3 64.3 17.6 19.5 1.7 105.6 32.6 0.9 20.8 12.2 163.7 45.5 40.6 35.6 19.6 62.6 11.4 21.4 7.5 12.6 23.6 54.5 48.3 51.4 76.4 127.5 42.2 42.8 29.5 26.7 8.4 11.4 21.6 53.5 42.3 57.5 28.1 47.6 76.4 9.2 32.1 5.9 52.5 5.5 7.8 29.0 30.2 0.9 3.8 58.8 23.3 41.4 26.9 7.6 21.6 33.5 34.3 28.1 32.4 31.8 37.0 49.8 41.2 33.9 34.4 44.2 30.4 8.4 9.6 4.7 37.9 24.5 2.4 13.8 18.9 4.6 1.0 9.4 6.5 3.3 18.6 8.8 3.7 0.0 47.1 11.3 8.5 1.9 41.3 18.2 9.4 17.7 8.4 6.0 4.0 8.3 23.3 121.0 11.1 19.4 22.2 22.2 1.1 5.0 43.5 112.0 0.0 5.3 18.2 18.3 10.4 22.5 20.0 5.0 31.2 7.2 12.2 57.7 34.6 8.2 15.1 2.4 30.6 11.9 3.8 5.5 17.1 17.2 38.0 3.3 2.1 0.0 4.9 6.4 1.3 17.1 2.4 1.1 36.1 4.5 2.1 18.7 10.2 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Microtubules "Nuclear speckles, Mitotic spindle" "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 1.5 3.1 1.7 3.3 1.9 1.7 2.4 1.4 1.9 2.5 3.8 2.4 3.0 1.5 3.2 2.5 3.9 2.0 1.0 1.4 1.6 9.1 5.2 3.3 5.8 2.0 1.7 1.9 4.5 2.9 4.4 2.6 1.7 4.0 2.2 0.6 3.7 2.6 0.5 3.1 4.2 1.2 1.6 5.8 3.4 3.8 1.9 2.7 7.2 0.4 5.0 2.6 2.2 2.3 2.1 3.4 3.5 2.8 1.9 2.1 10.9 0.9 2.1 1.3 1.7 5.4 5.0 13.1 3.5 2.8 2.5 3.8 5.2 4.8 1.3 3.5 6.4 2.9 5.8 10.1 3.3 1.8 3.7 4.8 1.8 2.5 5.8 1.8 0.9 1.9 4.3 1.3 1.5 4.7 1.9 3.4 3.3 3.7 1.0 4.9 2.3 5.9 7.0 5.7 6.4 1.5 3.0 6.3 1.6 4.7 9.3 2.4 0.8 1.3 2.2 1.6 1.0 1.5 1.8 8.9 2.0 1.6 3.1 3.3 0.9 1.2 0.7 0.5 0.8 2.8 0.6 0.7 0.1 4.2 0.7 1.0 0.4 1.3 1.1 14.8 0.5 0.8 1.7 1.9 1.4 1.9 1.4 1.6 2.0 1.7 1.7 1.6 1.9 2.3 2.7 9.6 19.3 3.9 22.9 2.8 9.2 8.3 7.4 2.8 10.1 14.1 1.7 12.8 11.6 25.8 8.4 17.6 19.1 14.9 7.9 5.8 9.5 12.8 6.0 2.9 10.3 7.0 0.7 6.0 9.2 3.9 6.1 15.2 26.6 3.2 3.3 9.4 3.9 1.7 0.5 14.4 10.2 5.0 2.7 2.0 3.4 4.4 3.6 2.8 4.0 2.6 3.1 1.5 1.6 3.9 17.2 2.6 7.2 8.6 13.4 4.3 14.3 1.8 0.0 11.7 3.0 19.9 11.4 8.8 1.6 11.1 4.9 7.8 15.9 4.2 NELFCD "HSPC130, NELF-C, NELF-D, TH1, TH1L" ENSG00000101158 "Negative elongation factor complex member C/D" Q8IXH7 20 58981208-58995133 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050641, HPA066262, HPA074936" Enhanced Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear bodies" "Vesicles, Cytosol" "HPA050641: AB_2681198, HPA066262: AB_2685644, HPA074936: " "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (6.20e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.47e-1)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.07e-3)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.62e-2)" "unprognostic (2.96e-1)" "unprognostic (9.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" 18.9 29.5 20.5 17.7 22.8 23.8 24.5 21.7 23.4 20.7 21.2 18.2 19.3 18.2 16.3 32.9 24.4 16.2 16.9 19.6 21.0 31.7 31.2 14.7 26.4 21.2 20.9 25.2 21.2 30.7 31.8 25.6 21.8 20.4 17.9 31.9 30.0 17.1 29.4 25.9 19.6 14.1 20.8 20.7 19.3 27.9 21.5 31.5 28.5 20.5 27.9 22.6 22.7 24.3 54.7 57.6 68.5 71.9 22.5 38.9 49.6 42.4 38.8 117.1 66.8 189.6 70.7 68.3 64.0 39.8 60.8 89.1 90.1 98.0 94.8 22.4 64.1 90.5 72.4 150.5 26.7 64.2 60.1 40.9 34.3 44.2 32.8 32.8 68.3 54.0 118.1 51.8 53.3 198.2 135.6 95.4 40.3 151.5 122.9 78.4 56.6 121.1 49.0 76.5 75.9 112.6 126.0 148.3 85.9 38.2 157.5 75.0 30.2 91.6 88.8 36.3 67.7 44.4 80.0 71.1 53.7 57.3 80.6 20.0 44.6 22.9 42.0 51.5 50.0 48.6 39.7 51.2 64.9 44.5 37.7 40.1 5.6 47.1 68.8 33.0 39.7 49.0 20.5 22.8 21.7 23.4 19.6 21.0 21.2 20.9 21.8 20.8 21.5 24.3 23.0 9.6 27.6 18.3 50.5 30.2 62.6 43.8 40.9 67.3 32.7 34.2 10.9 47.1 24.3 22.0 41.7 133.1 35.5 14.5 50.9 57.0 18.8 26.2 33.3 26.7 23.4 60.0 23.0 31.4 69.2 26.2 26.5 27.4 16.5 50.9 23.2 24.1 36.9 55.5 22.8 21.9 26.4 15.3 24.0 32.1 37.0 24.0 26.6 10.3 48.1 52.9 49.4 21.1 23.6 34.9 14.4 26.4 37.4 37.8 27.8 49.9 15.0 61.5 39.5 31.6 34.2 63.1 94.9 40.5 31.4 103.0 48.5 43.9 36.2 52.8 NEMF "FLJ10051, NY-CO-1, SDCCAG1" ENSG00000165525 "Nuclear export mediator factor" O60524 14 49782083-49852821 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004160 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 830000 "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA004160: AB_1079884" "unprognostic (9.92e-2)" "unprognostic (6.03e-2)" "unprognostic (4.44e-2)" "unprognostic (3.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.65e-1)" "unprognostic (9.15e-3)" "unprognostic (7.62e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.50e-1)" "unprognostic (1.12e-1)" "prognostic favorable (2.85e-4)" "unprognostic (3.61e-1)" "unprognostic (2.36e-1)" "unprognostic (8.98e-2)" "unprognostic (1.81e-2)" 16.5 13.8 9.5 18.0 13.0 42.1 14.7 18.1 14.7 16.2 5.9 13.6 10.0 16.2 13.5 22.5 12.2 13.2 17.7 7.9 10.6 14.9 11.9 13.8 17.9 11.8 11.6 15.2 15.2 24.8 10.3 18.2 11.9 16.0 14.5 14.7 14.6 15.8 23.0 14.3 13.6 15.7 10.9 15.5 14.1 10.7 10.7 16.3 18.5 21.5 17.9 18.0 11.6 18.4 34.3 39.2 35.9 24.1 37.3 31.0 32.1 42.0 28.3 27.6 27.3 23.2 35.3 13.3 32.0 35.7 21.2 47.5 34.1 26.7 42.2 38.9 22.7 38.7 40.3 29.1 23.8 50.7 33.4 26.8 19.6 29.9 27.2 36.3 39.8 23.8 47.3 36.2 37.7 30.6 31.2 17.9 21.9 28.6 36.8 32.6 35.5 20.8 33.7 44.8 23.6 22.2 41.6 40.4 39.2 37.2 37.6 31.1 47.2 39.2 34.4 26.6 28.9 24.5 47.6 40.9 14.7 23.9 35.5 76.4 38.9 45.8 45.7 36.9 44.8 83.7 47.1 44.4 33.9 86.7 55.6 59.1 61.3 47.8 54.4 79.7 46.1 20.3 9.5 13.0 18.1 14.7 7.9 10.6 11.8 11.6 11.9 10.9 10.7 18.4 66.2 41.7 76.7 65.3 81.1 34.4 67.4 81.6 29.6 92.1 31.7 43.1 97.2 34.3 74.4 44.1 100.1 85.8 78.4 51.8 37.2 57.0 13.9 52.2 60.1 65.2 54.0 57.0 75.7 39.1 58.1 53.0 41.8 60.7 89.3 68.0 49.6 28.1 58.9 131.2 80.7 48.9 71.2 48.7 57.0 13.1 65.9 57.9 24.9 62.8 79.4 54.8 82.4 56.8 99.5 46.4 68.5 67.4 50.0 66.1 59.4 29.9 82.4 90.0 72.3 65.7 70.7 83.0 58.3 32.5 34.1 108.4 66.9 64.1 54.6 88.6 NEO1 "HsT17534, IGDCC2, NGN, NTN1R2" ENSG00000067141 "Neogenin 1" Q92859 15 73051710-73305205 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 231.8;Excitatory neurons: 124.5;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 439.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009320, HPA027804, HPA027805, HPA027806" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 390000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB009320: AB_2150998, HPA027804: AB_10600771, HPA027805: AB_10601755, HPA027806: AB_10601006" "unprognostic (1.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.60e-3)" "unprognostic (3.76e-2)" "unprognostic (5.44e-1)" "unprognostic (3.83e-2)" "unprognostic (8.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.22e-1)" "unprognostic (3.30e-2)" "unprognostic (5.51e-2)" "unprognostic (8.05e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-2)" "unprognostic (3.75e-1)" 9.6 7.4 28.9 8.9 43.8 1.5 16.7 38.1 31.4 18.2 10.7 46.0 27.3 19.6 9.9 11.5 21.9 19.6 7.8 29.4 29.2 23.4 8.7 15.9 3.9 34.6 38.0 24.8 17.2 41.8 6.7 1.7 35.6 33.0 55.1 19.5 18.3 36.0 30.9 37.5 26.5 23.3 28.7 5.3 22.9 13.5 36.6 7.2 18.2 24.8 6.2 10.5 9.6 60.0 8.9 42.9 50.1 33.2 29.6 8.6 12.5 3.3 4.1 8.2 1.7 6.4 42.8 2.5 4.9 9.4 30.8 1.9 35.3 19.5 3.5 15.8 26.0 29.0 0.5 6.0 8.6 0.8 0.9 21.3 35.4 1.6 16.2 9.5 0.0 22.3 0.2 53.9 2.0 26.8 10.5 0.7 47.9 6.7 3.6 23.9 26.8 5.8 15.8 23.7 22.7 32.1 40.2 17.6 20.7 39.9 18.6 5.3 0.1 38.0 19.9 12.5 9.3 22.8 45.2 6.2 8.2 8.3 10.9 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.2 0.3 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 28.9 43.8 38.1 31.4 29.4 29.2 34.6 38.0 35.6 28.7 36.6 60.0 3.1 9.6 10.4 231.8 2.3 14.1 8.2 20.7 13.6 15.7 14.2 18.2 6.9 21.5 11.4 22.0 14.6 0.5 4.8 55.6 1.9 11.6 3.3 14.4 13.4 3.4 60.1 3.0 124.5 6.4 0.8 14.6 20.9 24.6 0.0 11.8 5.7 8.9 0.9 10.1 72.8 51.2 10.2 1.2 2.7 7.1 31.7 1.2 10.6 62.8 0.1 12.5 2.1 120.1 439.4 9.9 40.0 62.8 2.6 11.5 39.6 15.5 12.7 21.9 6.6 22.2 10.2 11.8 20.3 14.7 25.4 0.3 6.0 3.1 60.5 7.2 NEXMIF "KIAA2022, KIDLIA, MRX98, XPN" ENSG00000050030 "Neurite extension and migration factor" Q5QGS0 X 74732856-74925472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 1.4;Club cells: 2.5;Hofbauer cells: 1.3;Respiratory ciliated cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HAP1: 3.7;Karpas-707: 5.9;SiHa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000407 Uncertain Supported "Nucleoplasm,Midbody,Mitotic spindle,Cytosol" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Midbody, Mitotic spindle, Cytosol" "HPA000407: AB_2665984" "unprognostic (1.04e-3)" "unprognostic (6.07e-5)" "unprognostic (1.81e-2)" "unprognostic (2.07e-5)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (3.71e-1)" "unprognostic (1.79e-2)" "unprognostic (1.64e-3)" "unprognostic (8.25e-2)" "unprognostic (7.58e-3)" "unprognostic (1.37e-2)" "unprognostic (3.80e-2)" "unprognostic (2.79e-4)" "unprognostic (6.94e-4)" 0.1 0.9 3.0 0.1 3.1 0.0 0.3 1.0 2.5 0.4 0.0 0.8 0.1 0.5 0.2 0.3 0.3 0.1 0.0 2.6 6.7 0.7 0.0 0.1 0.1 0.3 0.7 0.4 1.5 1.8 1.7 0.1 0.5 0.9 0.3 1.0 0.4 0.6 0.0 0.3 0.4 0.7 0.2 0.1 0.6 0.2 4.8 0.0 0.4 0.1 0.1 0.2 0.2 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 5.9 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.1 1.0 2.5 2.6 6.7 0.3 0.7 0.5 0.2 4.8 0.7 0.3 0.0 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.9 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NFKBID "IkappaBNS, IkBNS, TA-NFKBH" ENSG00000167604 "NFKB inhibitor delta" Q8NI38 19 35887653-35902303 "Predicted intracellular proteins, Transcription factors" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.9" "Cell type enhanced" "Detected in many" "B-cells: 152.7;granulocytes: 90.3;Langerhans cells: 418.5;Macrophages: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054778 Uncertain "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Cytosol "Nuclear bodies, Plasma membrane" "HPA054778: " "prognostic favorable (6.01e-4)" "unprognostic (9.60e-2)" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-2)" "prognostic favorable (5.43e-4)" "unprognostic (4.21e-2)" "unprognostic (7.68e-2)" "unprognostic (3.83e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (5.64e-2)" "unprognostic (6.83e-2)" "unprognostic (1.04e-1)" "unprognostic (5.21e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.34e-6)" 4.0 1.8 0.7 4.4 0.6 15.9 2.5 2.7 1.6 1.9 2.1 2.3 1.1 1.8 0.0 2.1 3.0 2.4 1.5 0.8 1.4 2.5 1.5 5.6 4.8 1.4 0.9 3.3 2.1 0.9 4.2 0.8 1.2 2.2 0.8 0.7 1.6 0.5 0.4 2.2 4.0 0.5 1.0 5.4 2.0 0.4 1.3 5.2 3.9 0.2 3.1 2.2 2.0 1.7 3.3 3.0 0.6 2.0 0.3 0.5 1.4 2.0 2.4 2.1 1.5 0.7 2.6 4.0 1.5 2.1 1.9 1.7 2.1 1.6 0.9 2.3 0.4 2.4 4.9 0.7 0.5 2.1 7.0 0.7 1.0 3.9 0.9 0.5 0.8 1.8 0.5 2.4 0.4 2.6 1.7 2.5 0.8 0.6 0.6 0.9 0.4 0.8 1.8 1.4 1.0 0.8 2.7 2.1 0.2 0.5 0.9 2.1 0.8 3.3 3.0 1.5 1.4 1.7 0.6 4.6 1.8 4.9 0.5 0.0 0.9 1.7 1.4 0.6 1.1 3.3 0.6 1.1 0.9 5.5 1.0 0.6 3.2 1.5 1.1 1.2 1.5 0.5 0.7 0.6 2.7 1.6 0.8 1.4 1.4 0.9 1.2 1.0 1.3 1.7 11.7 0.0 11.3 2.9 152.7 29.7 14.3 12.9 34.7 8.0 10.9 7.5 1.1 5.7 5.6 1.8 20.9 1.3 58.9 5.7 0.0 2.5 0.1 27.8 6.8 21.5 3.0 1.7 4.9 1.0 2.8 11.3 2.0 80.8 90.3 3.8 9.3 0.3 39.2 0.0 3.4 5.7 2.0 31.0 418.5 0.4 1.2 89.4 19.6 2.8 40.0 1.0 13.4 1.5 0.5 2.8 2.1 1.9 38.1 13.8 9.2 1.7 3.9 9.2 0.0 3.3 6.7 0.4 1.0 20.7 33.4 1.0 45.3 2.4 6.2 10.0 NFKBIE IKBE ENSG00000146232 "NFKB inhibitor epsilon" O00221 6 44258166-44265788 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002692, HPA005941, CAB010272" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010272: AB_2235977, HPA002692: AB_1079479, HPA005941: AB_1079478" "prognostic favorable (1.72e-5)" "unprognostic (1.43e-1)" "unprognostic (1.39e-2)" "unprognostic (2.37e-2)" "unprognostic (6.32e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (4.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-2)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (2.61e-2)" "unprognostic (8.83e-2)" "unprognostic (1.37e-2)" "prognostic favorable (8.07e-4)" 6.8 5.8 10.9 19.1 10.8 31.5 5.9 12.1 17.6 4.1 10.7 7.2 7.4 3.7 4.7 5.9 3.3 8.3 5.3 11.3 10.6 16.1 10.5 13.6 19.9 11.5 11.4 2.7 8.3 5.3 4.5 5.5 11.2 8.3 5.9 3.7 7.4 3.3 3.5 9.9 12.1 3.6 11.7 35.0 7.0 10.7 11.8 9.9 5.3 3.9 25.1 16.3 5.0 12.3 28.4 7.9 9.5 15.1 3.7 2.8 5.3 4.9 23.8 14.9 15.4 15.0 12.9 15.7 17.0 5.1 39.7 6.2 10.3 15.4 16.6 26.1 6.0 7.9 3.0 17.0 11.4 26.1 23.0 7.1 6.7 13.8 8.8 12.5 10.7 7.2 7.7 39.2 3.9 14.4 5.2 52.7 5.0 44.1 4.0 9.9 8.5 14.0 34.7 30.3 6.1 7.8 3.4 12.5 20.9 8.0 8.6 29.9 18.1 8.4 9.8 5.3 15.4 25.0 11.4 28.7 7.4 28.4 16.1 8.8 7.5 4.0 1.6 9.4 3.2 8.6 2.2 1.5 6.6 6.5 1.0 1.6 3.0 0.8 11.1 8.1 3.1 1.7 10.9 10.8 12.1 17.6 11.3 10.6 11.5 11.4 11.2 11.7 11.8 12.3 7.5 0.0 9.7 1.0 26.0 38.2 28.7 11.6 14.8 3.4 15.3 9.9 5.4 22.8 9.2 3.7 2.1 5.2 12.5 12.2 17.6 49.5 17.3 10.0 6.2 15.9 14.9 1.7 1.1 21.0 8.0 17.3 10.7 12.8 32.5 2.5 6.1 2.0 57.2 3.3 2.0 11.9 6.1 22.6 151.2 34.1 1.8 48.6 48.0 3.7 55.2 3.3 1.0 0.5 0.9 58.9 33.3 2.6 18.7 32.6 14.3 14.4 6.1 4.1 6.6 11.8 11.0 25.9 12.3 11.6 39.2 5.3 13.8 7.0 8.5 34.7 NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469689-23509862 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: AB_1079483" "unprognostic (2.63e-3)" "unprognostic (7.65e-2)" "unprognostic (2.84e-1)" "unprognostic (4.16e-3)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (8.87e-2)" "unprognostic (1.72e-3)" "unprognostic (5.64e-2)" "unprognostic (3.87e-3)" "unprognostic (7.10e-2)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (9.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.58e-1)" "unprognostic (1.70e-1)" 32.2 26.4 25.6 23.3 28.4 64.4 40.3 30.5 37.7 30.5 25.0 30.1 23.4 34.7 32.5 26.2 32.0 17.6 23.7 25.9 26.6 31.3 32.9 24.2 35.3 27.1 27.0 39.6 25.7 33.3 20.8 29.2 27.7 24.8 29.0 25.2 24.6 26.6 53.4 35.2 26.8 31.4 27.7 28.6 27.0 28.6 26.9 37.5 28.4 39.2 36.8 32.3 27.7 31.7 37.6 73.1 54.5 51.5 52.0 37.3 72.1 48.6 50.7 101.3 81.4 72.1 66.8 92.6 35.0 44.7 71.1 63.7 109.0 60.1 118.7 61.8 57.3 83.2 44.1 229.3 70.5 110.4 56.9 46.5 75.0 79.9 94.4 39.6 52.2 69.5 93.6 64.1 50.4 88.8 82.3 86.0 69.5 84.8 97.1 67.1 65.6 47.9 65.7 70.4 55.6 62.8 57.6 68.3 83.8 55.0 42.2 70.4 39.8 47.8 57.3 45.1 71.3 79.4 148.7 133.3 20.6 56.1 52.2 67.0 62.3 58.5 88.0 71.8 93.5 129.0 94.6 89.9 74.8 107.7 121.3 95.5 19.1 109.5 71.7 79.1 116.1 93.3 25.6 28.4 30.5 37.7 25.9 26.6 27.1 27.0 27.7 27.7 26.9 31.7 33.8 35.3 29.2 2.9 52.1 70.6 63.8 78.2 72.8 23.2 25.5 31.2 20.2 21.5 46.8 27.6 16.7 59.3 45.3 19.9 33.2 38.6 7.2 24.3 25.9 36.5 24.6 35.1 7.5 36.0 43.3 34.4 16.3 27.5 45.0 23.2 25.4 21.4 29.8 25.2 6.8 22.7 28.5 19.2 39.0 6.9 35.1 21.1 32.0 9.4 34.3 26.8 46.4 4.0 11.0 31.1 22.8 28.2 30.4 42.9 25.8 35.5 36.6 28.6 19.7 51.5 36.0 68.7 64.2 39.6 67.6 57.2 47.6 20.5 27.2 49.5 NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 385.3;skeletal muscle: 376.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: AB_10796668, HPA076267: " "unprognostic (2.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-3)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.19e-2)" "unprognostic (2.94e-2)" "unprognostic (5.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-2)" "unprognostic (5.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.68e-3)" "unprognostic (3.21e-1)" 61.0 91.8 322.8 32.9 334.0 31.7 61.4 312.4 385.3 68.8 312.1 47.0 39.7 63.4 98.3 51.7 65.3 47.1 133.0 332.8 329.8 71.7 59.1 50.3 31.8 316.3 322.1 67.8 46.4 87.6 3.0 46.4 318.1 80.1 51.1 157.0 46.3 88.9 376.8 32.6 35.6 74.6 324.8 37.0 41.5 54.2 334.5 39.6 74.0 291.8 37.4 69.2 2.7 320.9 62.1 127.8 151.7 99.7 138.4 63.9 70.4 100.7 88.4 110.5 94.0 133.2 90.5 38.4 113.8 108.9 110.2 118.2 120.3 64.7 121.5 42.6 104.6 61.0 88.4 110.6 117.7 44.5 36.1 83.4 183.3 60.8 132.9 83.7 79.5 45.7 105.0 64.7 112.8 106.5 35.9 53.5 152.7 198.8 55.0 65.6 72.8 63.1 109.8 168.3 145.8 117.0 107.1 90.1 239.1 149.1 141.9 82.6 64.6 138.3 92.3 85.7 161.7 96.9 268.2 66.4 76.8 90.1 106.4 66.4 62.1 99.0 87.2 65.2 109.9 107.7 106.1 101.9 59.2 105.7 122.6 106.8 23.4 86.7 76.0 62.8 133.5 108.0 322.8 334.0 312.4 385.3 332.8 329.8 316.3 322.1 318.1 324.8 334.5 320.9 10.8 19.2 27.4 21.5 26.2 7.1 10.6 3.7 75.1 10.4 9.1 5.8 10.1 1.5 21.6 5.5 10.4 5.9 5.0 12.1 5.9 33.6 1.9 16.2 14.6 15.8 26.5 12.0 58.3 23.4 4.5 23.0 30.1 9.4 20.3 5.5 7.5 3.8 4.2 16.8 54.0 14.4 4.1 3.8 3.6 4.0 9.0 8.4 8.8 16.9 11.6 15.1 0.0 12.5 22.2 29.9 20.0 8.6 25.0 9.2 12.6 7.8 59.8 11.2 13.1 10.5 19.6 5.2 4.3 55.2 5.1 6.7 19.9 5.7 15.4 8.7 NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910818-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 101.2;monocytes: 57.7;Prostatic glandular cells: 90.5;Urothelial cells: 80.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.6" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.6;monocytes: 7.1" "Cell line enhanced" "Detected in some" "AF22: 25.2;EFO-21: 29.5;HUVEC TERT2: 27.8;TIME: 16.3;U-937: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: AB_2680872, HPA075115: " "unprognostic (9.71e-3)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.50e-2)" "unprognostic (2.88e-2)" "unprognostic (5.72e-4)" "unprognostic (5.46e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-2)" "unprognostic (4.27e-3)" "unprognostic (9.99e-2)" "unprognostic (7.76e-2)" "unprognostic (4.37e-4)" 4.7 1.3 8.1 3.0 9.6 2.2 3.2 11.8 6.6 3.2 12.3 4.9 0.8 3.2 1.4 3.1 2.3 4.3 2.2 6.6 5.9 1.1 0.9 3.4 0.8 1.5 9.1 1.6 0.6 1.6 2.6 2.2 4.6 3.5 1.9 0.3 1.5 4.8 0.8 1.4 1.7 6.9 0.8 2.8 1.9 2.4 6.9 1.0 2.7 2.4 0.9 3.7 2.3 0.0 0.4 0.6 25.2 0.1 0.3 1.0 0.2 0.9 4.7 0.1 0.4 0.1 0.0 0.2 29.5 2.6 0.1 0.0 1.6 0.0 0.6 0.1 0.6 0.1 0.1 0.0 0.1 0.1 1.4 0.5 0.0 0.9 0.0 0.1 27.8 0.1 0.0 4.1 0.2 0.2 0.1 2.1 4.8 0.0 0.0 0.1 1.4 0.0 0.1 2.9 0.6 5.7 0.0 0.0 0.0 7.1 0.1 1.7 16.3 0.0 1.6 2.0 0.0 0.1 0.0 0.1 1.1 20.5 0.0 5.0 7.1 14.3 2.0 4.7 1.9 0.0 1.0 1.7 4.1 0.0 0.1 0.2 15.6 1.0 3.7 0.0 0.1 2.3 8.1 9.6 11.8 6.6 6.6 5.9 1.5 9.1 4.6 0.8 6.9 0.0 29.2 0.0 1.9 1.0 7.3 0.5 101.2 0.0 0.6 0.9 5.0 3.7 19.6 21.5 0.0 1.8 0.0 17.9 10.1 2.0 0.0 0.2 4.7 3.3 2.8 32.9 1.2 17.3 7.8 0.7 24.3 15.2 0.5 9.0 7.6 0.9 51.0 19.0 19.1 0.0 5.8 3.7 0.0 49.0 0.5 7.4 31.7 19.7 1.8 19.7 57.7 1.5 32.0 5.5 1.1 0.6 3.1 21.4 2.8 90.5 7.8 2.9 0.0 0.5 26.3 39.7 12.6 2.7 3.7 0.3 0.3 24.9 17.0 2.9 3.8 80.7 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NIFK "hNIFK, MKI67IP, Nopp34" ENSG00000155438 "Nucleolar protein interacting with the FHA domain of MKI67" Q9BYG3 2 121726945-121736911 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015382, HPA035735, HPA035736, CAB075728, CAB075729" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB015382: AB_2142390, CAB075728: AB_2665734, CAB075729: AB_2665735, HPA035735: AB_2674758, HPA035736: AB_2674759" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (3.49e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (1.21e-1)" "unprognostic (4.15e-3)" "prognostic unfavorable (2.92e-6)" "unprognostic (7.74e-3)" "unprognostic (4.63e-2)" "unprognostic (3.21e-2)" "unprognostic (6.02e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (5.01e-11)" "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" 29.3 24.8 18.1 31.9 18.6 31.5 37.3 18.7 21.8 25.4 17.9 24.8 25.1 28.5 21.9 34.6 27.5 25.1 22.9 19.3 18.7 25.7 34.1 17.9 47.2 18.5 17.8 36.5 32.6 17.9 16.7 25.6 18.4 24.6 25.6 23.0 17.9 17.8 38.3 34.5 20.1 24.8 19.1 22.3 22.5 21.8 18.3 32.9 25.2 18.3 42.4 43.3 24.5 20.1 118.4 37.6 68.8 68.3 57.9 80.6 90.2 90.6 75.2 105.0 113.2 105.9 55.0 152.4 111.4 66.9 93.1 72.9 149.4 116.4 153.4 101.3 85.7 155.0 44.5 92.9 82.6 141.1 81.7 80.6 126.7 137.4 184.4 48.7 75.9 60.3 174.5 73.9 90.5 58.2 109.5 140.9 175.3 132.4 122.5 102.5 80.7 191.2 92.1 72.4 88.1 91.8 56.6 105.1 200.7 62.2 52.0 123.1 45.7 72.8 123.5 85.6 129.3 87.5 150.6 182.1 55.7 143.9 101.5 41.8 54.2 28.8 59.2 65.3 83.4 73.6 72.3 68.6 72.1 74.8 84.5 79.4 4.0 81.5 62.5 64.0 68.9 75.1 18.1 18.6 18.7 21.8 19.3 18.7 18.5 17.8 18.4 19.1 18.3 20.1 51.1 44.8 25.9 8.1 56.3 98.4 128.9 87.0 81.4 25.8 51.2 88.8 21.5 24.3 62.2 14.7 12.5 74.9 62.7 18.9 46.9 64.2 23.7 43.8 126.9 47.7 28.1 41.8 8.2 45.2 90.6 68.7 32.6 39.9 54.5 47.9 26.0 33.2 54.4 13.5 7.2 41.3 42.7 34.5 32.8 8.0 57.5 39.0 23.2 10.3 59.1 48.0 54.6 13.0 8.0 51.5 28.4 45.1 33.3 107.0 18.4 58.4 41.9 45.8 39.5 72.7 54.3 81.1 83.9 79.3 101.4 48.8 52.5 97.7 60.5 125.2 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.5;Muller glia cells: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 11.2 4.4 10.1 19.9 10.8 43.2 8.9 9.5 15.0 7.2 0.0 8.3 4.8 7.7 2.8 12.9 10.5 8.9 18.2 10.4 0.9 6.7 5.7 9.5 25.9 0.0 1.3 9.7 7.2 9.0 8.9 16.8 0.0 6.9 8.6 19.1 5.4 5.4 6.0 12.9 7.1 10.3 0.0 16.2 9.3 5.2 3.0 19.9 7.7 7.4 23.7 13.6 5.7 7.5 29.1 21.6 42.4 36.8 16.7 26.8 20.4 26.5 22.1 21.4 18.0 14.7 14.6 48.5 17.7 35.5 19.9 32.5 34.2 16.3 45.3 34.7 10.4 25.1 13.2 12.3 9.8 41.6 57.5 18.4 11.4 37.2 14.9 13.3 34.6 25.9 6.6 26.3 31.8 36.8 22.6 14.0 6.4 10.1 23.6 37.1 81.6 5.7 20.1 42.9 18.6 22.2 34.0 9.6 25.1 10.2 21.2 39.3 50.9 55.2 74.3 20.5 29.0 18.6 12.1 34.3 14.4 32.8 30.4 31.9 2.9 24.0 3.9 2.5 3.3 8.9 2.4 6.2 2.0 6.2 5.1 4.7 9.6 2.9 2.1 7.7 2.5 1.4 10.1 10.8 9.5 15.0 10.4 0.9 0.0 1.3 0.0 0.0 3.0 7.5 34.0 6.4 7.7 100.2 85.6 18.4 9.1 10.2 18.8 13.3 13.3 10.9 68.0 14.3 27.1 11.0 62.6 12.4 102.7 8.7 3.9 7.3 22.2 17.3 28.5 26.7 12.6 29.0 240.5 4.2 11.3 32.9 7.7 14.9 31.6 3.9 21.8 4.4 22.7 6.7 110.4 5.7 20.3 46.8 42.2 10.4 8.4 61.3 23.2 63.7 63.2 150.2 57.7 105.6 75.1 5.2 6.2 9.4 48.1 16.5 3.2 7.3 29.4 21.0 32.9 44.9 24.1 0.2 4.3 20.1 21.0 9.7 56.2 21.8 6.9 15.5 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NINL "KIAA0980, NLP" ENSG00000101004 "Ninein like" Q9Y2I6 20 25452697-25585531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 42.4;Granulosa cells: 29.6;Inhibitory neurons: 32.6;Oligodendrocyte precursor cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 37.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000686 Uncertain Uncertain "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytokinetic bridge, Cytosol" "HPA000686: AB_1079193" "unprognostic (7.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (4.84e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (8.56e-2)" "unprognostic (2.50e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (3.39e-1)" "prognostic favorable (1.03e-5)" "unprognostic (3.95e-2)" "unprognostic (2.72e-1)" "unprognostic (1.51e-1)" "unprognostic (6.26e-2)" 4.0 8.6 4.9 2.0 5.9 0.6 4.0 10.4 6.1 10.1 8.8 9.8 3.2 7.2 7.2 5.8 5.2 3.3 4.0 4.4 6.9 15.1 8.1 4.1 2.2 7.9 7.1 18.9 5.4 8.2 9.9 1.5 7.0 8.8 2.1 4.7 4.4 3.7 4.5 2.4 3.9 3.5 5.5 4.9 6.3 7.7 6.5 15.7 10.2 1.2 2.2 3.6 8.5 6.8 1.0 10.8 23.0 15.1 2.6 7.5 7.1 3.6 3.1 3.1 4.4 2.8 7.5 0.6 5.0 5.6 7.6 0.8 3.4 0.7 2.6 0.5 4.7 1.6 5.0 37.5 5.4 0.6 0.1 9.2 0.7 3.6 0.0 8.8 6.8 17.8 1.9 0.3 3.8 9.6 21.7 0.7 6.5 0.1 1.1 0.5 17.9 0.8 1.5 1.3 22.7 16.0 8.2 3.0 9.1 18.3 4.9 6.4 0.3 0.1 8.6 0.1 0.2 2.3 4.4 0.1 0.2 0.6 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.9 10.4 6.1 4.4 6.9 7.9 7.1 7.0 5.5 6.5 6.8 1.2 0.0 14.6 42.4 0.8 2.0 4.9 2.5 5.7 3.0 2.8 3.3 6.5 12.8 4.8 7.3 25.0 2.8 0.6 0.4 0.0 5.6 0.6 4.2 7.3 2.3 6.1 0.0 7.4 1.2 1.3 8.7 4.6 3.4 0.0 29.6 8.9 8.4 2.3 8.4 32.6 2.3 8.2 0.3 2.0 2.7 13.1 0.8 0.0 12.2 0.0 3.2 2.1 47.3 19.4 2.8 1.5 12.4 0.9 4.5 0.7 8.8 13.7 1.9 6.6 10.8 4.7 2.5 5.0 4.3 0.9 1.5 1.1 21.0 2.5 1.9 NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA040834: AB_10796562, HPA058239: AB_2683650" "unprognostic (4.92e-2)" "unprognostic (9.77e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-2)" "unprognostic (9.38e-2)" "unprognostic (6.02e-2)" "unprognostic (7.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.40e-2)" 11.5 9.4 5.6 14.7 8.6 25.1 13.5 12.0 7.3 12.9 7.8 12.2 10.0 13.4 6.6 11.4 10.5 11.1 7.7 5.3 5.9 11.6 12.7 11.9 16.5 7.3 6.6 17.6 13.1 19.6 5.0 13.9 8.2 11.1 12.2 22.4 11.2 10.7 9.5 14.2 13.2 12.4 6.3 15.3 13.4 14.2 6.9 29.8 17.2 14.3 16.7 12.6 7.5 11.1 22.5 13.1 33.3 15.6 20.7 22.3 24.4 17.6 19.3 18.9 15.7 18.2 22.6 33.5 11.3 21.6 22.2 19.2 28.9 15.9 27.0 27.9 14.7 40.9 57.4 13.3 14.0 48.4 26.4 16.5 19.3 21.3 28.1 18.1 24.0 20.8 39.3 24.5 17.9 10.8 33.8 18.1 16.0 12.9 11.3 28.2 51.9 13.0 13.1 31.4 24.5 17.2 84.6 22.5 18.0 26.2 23.0 27.3 26.3 24.9 27.1 21.0 13.3 17.7 25.5 39.1 13.6 32.4 19.1 10.9 2.9 4.3 3.2 2.2 3.0 2.8 2.7 2.9 2.3 3.1 2.9 3.3 7.7 2.8 3.3 3.4 2.1 1.6 5.6 8.6 12.0 7.3 5.3 5.9 7.3 6.6 8.2 6.3 6.9 11.1 80.6 131.4 108.6 169.8 84.8 48.4 66.2 34.2 58.1 62.6 43.6 49.4 87.0 38.6 63.3 33.1 77.2 44.1 107.1 45.9 5.9 55.5 13.4 72.9 75.7 74.1 41.5 85.4 179.2 46.7 34.1 64.3 61.2 91.7 84.0 77.7 44.6 28.2 37.1 40.4 165.5 46.3 38.7 51.8 46.6 15.1 66.5 86.7 24.9 236.1 103.3 49.2 97.9 229.2 303.7 55.0 48.6 56.4 84.5 66.4 45.2 12.2 65.2 72.8 52.6 102.9 80.1 185.8 133.6 58.2 47.0 75.9 92.0 73.8 42.9 88.0 NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493068 "FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 169.3;Peritubular cells: 246.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Cytosol" "Vesicles, Microtubules, Cytokinetic bridge" "HPA023189: AB_1854495" "unprognostic (6.66e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-2)" "unprognostic (6.56e-3)" "unprognostic (4.96e-2)" "unprognostic (8.33e-3)" "prognostic favorable (1.91e-4)" "unprognostic (1.40e-2)" "unprognostic (5.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" 55.2 69.8 46.5 28.7 55.5 38.7 60.5 78.2 56.6 105.8 22.2 68.5 24.3 76.2 34.0 51.3 72.0 29.9 48.5 56.3 38.7 54.6 45.6 56.2 32.5 20.9 32.6 93.0 54.1 32.5 181.8 39.1 32.9 107.5 20.6 19.0 53.6 51.6 36.3 80.7 55.3 33.0 9.1 54.1 52.7 84.5 35.2 30.1 60.8 16.3 23.3 78.1 71.6 35.2 15.6 16.0 48.8 40.1 35.7 39.2 40.0 32.8 21.5 25.7 26.0 24.2 22.8 21.7 9.0 45.6 21.0 20.4 26.1 35.7 15.1 22.3 28.2 39.2 65.2 23.9 32.4 23.2 33.6 61.9 28.2 27.7 23.5 54.0 42.0 42.4 21.1 23.4 24.3 22.2 41.8 51.2 30.1 19.8 27.1 24.5 13.4 25.4 29.2 30.6 20.6 35.9 35.6 9.3 23.1 42.3 28.9 38.5 46.3 36.0 34.1 36.9 24.1 38.7 23.8 27.3 24.7 37.3 22.4 5.2 4.5 3.5 3.0 4.0 3.1 2.5 2.6 4.0 2.3 2.8 3.1 3.3 1.5 3.2 0.6 3.4 3.0 3.6 46.5 55.5 78.2 56.6 56.3 38.7 20.9 32.6 32.9 9.1 35.2 35.2 26.1 25.6 32.3 34.0 14.9 27.5 14.6 23.3 40.5 40.9 29.2 37.1 20.4 8.6 19.1 14.7 8.4 32.4 24.2 20.5 9.8 12.1 10.3 14.5 26.7 22.1 169.3 4.6 64.9 9.4 14.0 23.4 23.4 18.9 25.3 40.2 46.1 15.3 30.5 28.6 44.0 19.1 22.4 50.5 14.5 25.9 88.3 24.3 19.6 15.0 13.0 12.1 17.5 21.1 26.1 10.0 14.2 246.0 12.4 12.6 16.5 15.6 15.2 22.4 26.3 17.2 24.8 31.2 18.0 16.7 22.3 24.2 18.4 47.6 15.7 11.7 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600655-42648735 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 42: Non-specific - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: AB_2681540" "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favorable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.01e-4)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.05e-5)" 17.4 19.2 16.4 17.6 18.7 46.5 19.3 22.3 17.1 28.4 17.9 17.7 13.2 18.4 22.4 17.0 23.0 11.4 17.8 15.0 20.3 18.2 21.1 23.9 22.1 20.5 16.4 29.0 22.1 10.6 36.5 11.1 17.6 23.2 13.4 41.3 17.5 10.5 19.5 32.6 25.4 10.7 14.0 36.7 16.3 18.0 18.2 15.4 25.4 10.4 20.0 18.3 22.6 27.8 15.1 7.7 32.3 15.6 16.6 19.3 14.9 22.8 6.8 9.9 12.9 14.7 13.3 25.9 10.7 9.1 9.0 12.6 16.1 8.4 19.2 11.0 13.1 31.4 30.5 24.6 7.3 25.4 19.9 9.6 12.2 18.4 10.5 19.1 17.4 7.1 30.3 20.2 18.6 6.9 17.8 35.5 23.1 7.6 12.3 17.3 12.0 10.5 15.7 12.7 9.4 8.5 24.1 11.1 4.8 16.3 17.5 17.8 28.0 18.0 13.1 21.4 23.2 17.2 21.7 17.7 10.1 30.0 11.3 7.8 3.6 7.5 5.7 4.6 5.3 5.5 5.6 4.9 2.9 5.3 5.6 4.9 5.3 7.0 6.8 5.1 5.3 2.3 16.4 18.7 22.3 17.1 15.0 20.3 20.5 16.4 17.6 14.0 18.2 27.8 221.8 109.0 141.4 169.4 129.5 59.0 60.3 57.8 66.0 200.0 76.3 69.8 68.7 65.8 73.2 88.3 246.0 72.5 156.0 60.3 17.6 47.3 23.9 114.4 125.5 166.2 71.8 76.6 143.5 38.8 51.1 83.3 86.6 132.4 96.8 210.0 110.7 58.6 45.9 132.9 170.0 70.2 61.1 53.8 70.2 21.8 167.7 78.9 51.6 194.9 97.4 101.9 163.7 180.0 267.2 47.6 59.2 134.3 131.3 77.5 106.8 17.0 53.3 279.9 92.1 103.5 88.9 246.2 186.1 42.4 57.3 31.3 164.4 104.5 75.0 54.2 NKX2-6 "CSX2, NKX4-2" ENSG00000180053 "NK2 homeobox 6" A6NCS4 8 23701740-23706756 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "salivary gland: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTEC/SVTERT24-B: 5.6;JURKAT: 2.1;LHCN-M2: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025288 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA025288: " "unprognostic (1.86e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 78.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 154.3;Early spermatids: 261.1;Excitatory neurons: 315.5;Late spermatids: 355.3;Oligodendrocytes: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 45 "basophil: 29.9" "Lineage enriched" "Detected in single" 45 "granulocytes: 29.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: AB_2683160" "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 8.2 36.6 16.7 8.6 27.6 9.9 9.4 5.7 41.9 7.9 1.0 9.0 10.3 7.0 11.2 5.5 6.4 8.7 11.5 28.5 9.2 16.6 11.1 9.1 16.4 11.9 10.4 5.0 14.3 28.2 11.1 12.2 8.4 8.2 9.2 78.6 7.4 10.8 6.6 5.9 10.2 5.9 6.5 12.2 8.9 22.0 12.2 13.2 16.8 6.7 15.4 10.1 4.5 30.1 9.5 11.6 28.4 9.7 6.1 7.6 12.1 9.6 10.9 16.9 13.1 59.4 9.1 13.6 13.8 8.4 20.2 8.6 19.6 18.7 19.3 29.7 12.2 52.2 11.2 9.9 10.3 11.6 51.0 9.6 11.9 10.4 12.5 16.0 20.4 36.3 20.1 15.9 16.4 11.6 28.8 13.4 10.4 20.1 5.5 23.8 17.2 10.0 32.0 12.2 19.6 7.2 14.4 14.4 62.4 32.2 22.0 18.2 19.2 11.7 14.1 9.0 19.5 17.6 17.9 13.1 11.6 12.6 13.0 29.9 0.3 0.3 0.5 0.4 0.2 0.6 0.5 0.6 0.3 0.3 0.3 0.6 0.2 0.2 0.5 0.5 0.5 0.3 16.7 27.6 5.7 41.9 28.5 9.2 11.9 10.4 8.4 6.5 12.2 30.1 17.8 22.4 6.0 57.8 7.8 5.4 3.8 3.0 5.7 94.4 8.7 5.0 27.4 5.7 5.3 33.1 154.3 3.7 4.3 11.4 1.9 3.9 261.1 8.9 5.8 15.0 28.2 11.8 315.5 6.4 3.5 4.8 5.1 11.9 24.1 17.6 9.3 9.4 8.8 37.0 98.2 10.0 2.0 16.9 6.0 355.3 5.6 11.3 16.0 103.0 7.9 11.2 6.2 104.5 366.6 5.7 8.1 2.6 6.4 5.4 5.1 8.4 9.5 89.9 13.1 5.0 6.9 37.1 11.8 4.1 4.8 6.4 5.5 6.7 10.3 6.6 NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "B-cells: 10.3;dendritic cells: 18.8;NK-cells: 37.0;T-cells: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 8.8;HEL: 8.7;HL-60: 18.6;HMC-1: 9.0;JURKAT: 9.2;NB-4: 19.7;U-698: 28.9;U-937: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" 1.0 0.8 0.3 7.8 0.4 4.1 0.7 0.8 0.7 0.9 1.0 1.5 1.7 0.9 0.4 0.8 1.2 1.4 1.5 0.3 0.0 1.3 1.1 2.4 13.6 0.3 0.3 0.7 0.5 0.2 0.9 0.9 0.1 1.1 1.2 1.1 1.1 0.3 1.1 0.5 6.5 0.5 0.0 11.8 2.1 0.9 0.3 11.3 1.5 0.9 11.1 1.5 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.2 8.7 0.1 0.0 0.0 18.6 9.0 0.0 0.0 0.0 0.0 0.5 0.2 9.2 0.2 0.0 0.0 0.4 7.7 19.7 0.0 0.0 0.1 5.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.1 4.9 0.5 0.3 0.1 0.2 0.1 0.4 0.2 28.9 0.2 13.6 0.1 2.9 0.0 0.0 2.3 0.0 2.1 0.8 1.7 2.2 0.0 0.6 1.4 1.5 0.0 2.6 0.0 0.0 2.0 2.1 0.3 0.4 0.8 0.7 0.3 0.0 0.3 0.3 0.1 0.0 0.3 0.1 1.7 3.2 0.0 1.0 10.3 0.0 0.3 0.0 0.0 1.6 0.4 0.3 4.6 1.5 0.6 1.8 4.2 0.0 18.8 0.0 0.0 0.0 4.0 1.3 0.8 2.3 0.0 6.5 3.8 0.0 0.0 0.5 1.5 0.7 2.5 0.2 3.9 0.1 0.1 0.0 3.7 0.0 0.0 1.0 0.0 1.3 0.0 1.1 0.0 1.9 1.3 0.3 37.0 1.0 0.6 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.7 5.1 0.0 0.9 0.7 0.5 0.3 0.0 0.0 0.0 23.8 0.1 0.0 0.3 NLRP2 "CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2" ENSG00000022556 "NLR family pyrin domain containing 2" Q9NX02 19 54953130-55001142 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Extravillous trophoblasts: 216.1;Syncytiotrophoblasts: 97.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 78.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 42.2;BEWO: 177.9;OE19: 79.7;SuSa: 80.3;T-47d: 46.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021183 Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA021183: AB_2670615" "unprognostic (1.66e-2)" "unprognostic (9.28e-2)" "unprognostic (6.60e-2)" "unprognostic (6.50e-3)" "unprognostic (1.09e-2)" "unprognostic (4.57e-3)" "unprognostic (4.27e-1)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.63e-1)" "unprognostic (2.34e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.86e-2)" "unprognostic (7.57e-2)" 0.4 0.3 0.9 2.7 0.6 1.0 1.0 0.0 0.8 2.6 0.1 1.7 1.8 1.1 1.8 7.9 1.9 0.9 0.4 0.7 0.1 1.9 0.4 1.6 2.1 0.1 0.2 0.3 1.6 0.4 1.2 7.1 0.1 1.5 1.9 3.1 2.4 1.1 0.6 3.0 1.7 0.8 0.0 2.1 2.5 7.2 0.3 3.4 4.4 0.0 1.9 7.1 4.3 0.2 20.4 42.2 15.8 0.4 0.2 0.1 177.9 0.1 0.0 0.6 0.2 35.9 0.7 14.7 0.1 0.1 0.1 8.1 0.0 24.4 0.3 1.7 0.2 9.8 0.5 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.1 0.1 0.9 0.0 32.7 0.2 0.0 0.3 0.1 1.3 5.0 79.7 0.0 8.8 0.0 24.0 26.4 0.7 5.3 0.7 0.0 8.1 0.0 80.3 46.7 0.2 0.0 0.3 0.7 0.4 0.3 5.2 16.6 0.7 0.4 1.0 0.0 0.1 0.2 0.0 1.8 0.3 1.3 0.6 0.4 0.7 0.2 0.6 0.3 0.8 0.2 3.0 0.1 1.0 1.3 0.4 0.9 0.6 0.0 0.8 0.7 0.1 0.1 0.2 0.1 0.0 0.3 0.2 0.0 9.6 7.3 0.3 1.5 0.5 1.9 8.1 0.0 2.7 1.9 1.5 0.8 4.3 10.1 1.8 4.2 45.2 3.5 2.9 0.0 5.3 23.1 8.6 1.3 0.7 2.4 0.8 3.0 1.9 216.1 1.1 2.0 13.1 4.5 0.7 0.0 0.0 11.6 0.0 1.9 3.0 6.1 0.3 0.5 7.2 0.9 1.1 0.0 0.0 3.0 0.7 8.2 0.5 0.5 6.7 1.0 0.0 1.5 2.5 0.8 0.4 8.4 2.7 0.0 0.3 0.8 16.8 11.7 0.0 1.3 97.3 2.4 0.3 3.0 4.7 NLRX1 "CLR11.3, NOD9" ENSG00000160703 "NLR family member X1" Q86UT6 11 119166568-119184016 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 43.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 15.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061516 Supported Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Plasma membrane, Cell Junctions" "HPA061516: AB_2684548" "unprognostic (7.58e-2)" "unprognostic (3.71e-1)" "unprognostic (6.36e-2)" "prognostic favorable (2.47e-5)" "unprognostic (5.60e-3)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (8.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.59e-6)" "unprognostic (3.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (4.22e-2)" 8.1 10.7 4.9 4.7 5.0 6.5 7.0 4.7 5.5 10.5 6.4 10.8 4.8 10.1 3.4 43.2 9.8 5.2 17.0 4.7 4.6 8.8 9.1 5.5 5.0 5.3 5.1 4.0 9.6 6.0 4.8 4.2 5.4 8.3 3.4 2.7 10.3 6.8 24.1 21.5 6.4 5.8 5.1 8.1 7.3 3.5 5.1 4.7 7.9 13.7 10.5 9.6 16.5 5.2 5.3 15.6 1.6 12.2 5.1 5.9 2.4 7.0 8.0 3.4 5.9 0.9 13.0 9.5 21.0 8.9 5.1 13.1 4.7 4.0 1.1 12.5 5.0 12.6 5.5 8.6 7.7 4.4 7.0 6.6 16.4 4.5 8.7 6.9 7.0 12.5 0.1 6.2 3.6 14.2 7.5 10.7 7.5 6.9 8.6 14.6 2.1 3.1 8.2 6.8 2.3 7.9 10.4 5.5 4.5 2.4 17.7 13.0 8.2 6.8 6.0 6.1 3.6 2.2 2.6 3.3 1.0 13.4 4.9 2.8 3.5 15.4 0.8 1.5 1.0 0.5 0.8 1.2 2.1 0.4 0.9 1.0 8.1 1.4 1.4 0.9 1.4 2.3 4.9 5.0 4.7 5.5 4.7 4.6 5.3 5.1 5.4 5.1 5.1 5.2 3.0 0.0 7.9 5.9 3.2 2.5 1.7 4.5 2.8 1.3 4.1 4.2 12.8 2.8 4.2 7.3 2.1 3.6 1.4 7.3 1.9 7.1 2.0 8.7 2.8 3.8 2.4 3.8 5.9 3.8 2.2 3.5 8.2 4.1 0.0 5.7 5.3 10.2 6.5 0.0 4.0 3.7 2.0 6.0 1.8 4.7 1.2 4.0 1.8 2.8 6.2 6.1 5.2 5.5 2.8 5.5 7.6 1.2 1.8 1.6 3.9 5.3 7.2 3.2 0.0 2.9 2.7 1.9 2.0 10.8 4.7 0.5 2.8 2.1 5.5 1.2 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 21000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 63.6 84.4 79.3 74.7 81.6 77.0 63.1 78.7 102.2 38.2 79.0 60.1 38.8 49.7 46.8 91.0 48.6 20.8 37.7 88.0 92.0 65.4 83.2 41.3 73.9 83.9 78.4 33.6 67.8 52.8 47.4 39.2 82.4 38.7 77.6 218.4 50.7 30.4 35.6 57.5 33.1 66.3 76.5 48.5 41.8 25.3 81.0 61.1 41.3 20.9 95.8 72.2 48.9 80.1 483.6 833.1 285.9 444.8 118.6 183.7 479.7 355.3 227.3 652.2 489.7 656.9 288.1 754.2 372.4 304.1 272.4 252.1 542.5 553.3 553.4 398.4 729.3 504.9 605.8 975.9 237.1 575.8 243.8 177.8 341.7 493.1 458.6 120.6 404.6 247.8 739.0 270.0 392.8 720.4 715.2 647.1 390.7 957.5 739.3 446.9 587.6 751.3 511.5 320.2 418.6 461.1 188.1 521.0 385.3 246.2 554.0 419.6 279.5 476.9 452.2 307.0 774.4 374.0 840.9 956.3 286.2 480.4 385.8 1.1 55.0 2.1 47.2 77.1 69.3 96.4 50.3 53.8 134.0 67.6 54.3 60.4 1.7 69.6 48.6 84.8 49.1 68.4 79.3 81.6 78.7 102.2 88.0 92.0 83.9 78.4 82.4 76.5 81.0 80.1 53.1 32.1 30.5 0.0 71.3 132.4 97.5 198.8 88.8 283.3 98.8 118.1 34.2 65.8 92.3 71.7 285.7 180.0 25.4 54.2 150.6 211.3 34.2 40.2 107.2 85.1 89.7 81.8 0.0 201.5 269.7 85.0 64.2 37.2 45.7 113.5 27.8 123.3 207.1 40.4 0.0 107.4 101.7 25.7 88.9 93.7 61.2 48.9 129.9 0.0 47.2 105.6 27.8 0.0 0.0 194.0 50.5 58.6 113.8 170.6 12.2 195.2 42.0 323.7 13.1 83.0 182.9 22.7 98.8 139.4 133.1 88.5 38.0 215.5 157.7 98.2 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported "Plasma membrane,Midbody ring,Cytosol" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane, Midbody ring" "CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305" "unprognostic (7.21e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 503.5 428.3 308.0 259.5 319.0 329.4 489.1 328.0 379.9 439.2 431.1 409.2 335.1 383.4 236.1 610.6 350.6 187.0 403.9 313.7 338.6 478.1 428.4 339.6 288.9 326.6 320.7 500.1 632.0 201.8 234.9 204.8 321.3 367.7 330.4 63.3 432.4 247.5 545.7 540.3 307.6 286.2 326.8 336.0 403.5 77.8 333.3 190.0 305.3 353.7 289.1 463.5 464.2 333.4 1638.6 2233.9 466.1 913.7 969.3 1399.2 1449.2 1091.7 954.0 1404.8 1053.5 1789.7 792.3 1314.3 1662.9 913.0 706.6 956.2 947.3 1273.3 1035.7 1604.8 3283.2 1120.3 1345.8 2513.4 1116.1 1736.0 760.5 1324.1 1420.0 901.9 1466.4 914.6 860.9 856.5 1541.7 773.7 956.1 2741.9 931.3 2144.8 831.4 2974.6 3364.2 875.9 1731.8 2157.2 1417.9 1800.2 1160.6 641.9 674.1 1472.7 1583.0 806.1 1201.7 1268.5 1013.5 1462.8 1158.2 1135.2 1774.8 1520.9 2176.6 1558.1 815.1 919.1 819.2 66.8 243.4 14.0 166.7 325.5 235.6 338.9 211.9 183.3 439.5 259.2 153.5 170.0 13.8 251.6 282.5 478.1 211.2 298.2 308.0 319.0 328.0 379.9 313.7 338.6 326.6 320.7 321.3 326.8 333.3 333.4 9.7 28.9 67.2 0.0 146.8 14.5 8.3 10.8 918.0 0.9 41.6 35.9 0.0 22.8 85.7 5.5 0.0 10.0 10.1 7.1 37.2 47.4 0.6 16.4 34.3 60.9 14.6 298.2 0.0 34.5 27.8 99.0 438.3 21.3 42.9 6.8 22.9 37.6 16.4 0.0 0.0 19.3 8.2 34.8 17.4 2.1 25.7 136.7 10.6 0.0 55.5 0.4 2.1 0.0 0.0 40.7 15.6 12.8 778.5 7.6 11.7 33.8 63.6 0.8 6.6 10.2 43.3 0.6 5.6 1490.1 14.9 8.8 87.0 6.8 25.0 11.0 NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 68.6;Karpas-707: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049795 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" Centrosome "HPA049795: AB_2680886" "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (3.58e-2)" "prognostic favorable (3.70e-6)" "unprognostic (3.56e-2)" "unprognostic (2.35e-1)" "unprognostic (5.20e-3)" "unprognostic (2.21e-2)" "unprognostic (3.27e-2)" "unprognostic (2.43e-1)" "unprognostic (2.06e-2)" "unprognostic (1.78e-1)" "prognostic favorable (5.60e-4)" "unprognostic (9.25e-2)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "unprognostic (5.64e-2)" 22.1 11.5 14.6 14.3 15.0 12.6 20.2 17.0 18.9 21.8 15.4 15.3 17.8 11.2 18.5 39.5 16.4 14.1 15.5 15.2 15.4 32.5 53.7 21.7 17.5 14.9 14.8 22.7 45.1 64.1 19.8 14.8 15.2 23.7 13.0 8.8 31.2 13.6 27.2 23.2 22.4 8.8 14.8 31.1 26.0 9.7 14.4 17.3 25.6 13.4 20.0 18.8 25.6 15.2 11.7 2.7 3.2 7.9 21.4 28.0 18.1 17.0 22.4 3.5 5.8 0.1 29.8 6.8 10.0 13.8 7.2 18.5 3.8 9.4 10.0 68.6 3.5 5.1 5.6 5.7 20.3 4.8 0.8 22.5 23.5 6.3 11.8 20.8 25.1 10.8 0.5 79.0 24.6 8.4 4.3 4.3 3.9 40.2 10.0 1.6 29.7 42.1 28.9 19.5 2.2 0.5 7.3 6.4 9.0 19.2 18.4 4.5 20.6 13.5 2.9 12.9 4.6 37.5 31.4 4.1 23.1 4.9 13.8 16.4 5.4 9.3 25.1 5.1 30.5 13.4 43.7 29.2 6.1 9.1 39.4 30.2 9.8 17.2 14.5 17.2 31.6 18.1 14.6 15.0 17.0 18.9 15.2 15.4 14.9 14.8 15.2 14.8 14.4 15.2 42.2 38.5 21.7 11.8 22.6 21.0 36.4 38.2 38.7 8.4 33.4 37.5 15.5 21.5 27.9 23.9 8.4 53.3 43.7 32.8 52.8 30.5 17.8 42.4 16.8 33.4 4.2 10.3 26.2 35.5 75.7 22.7 49.5 37.4 1.3 8.3 55.3 45.2 62.4 11.8 20.6 34.8 22.4 32.5 9.6 30.8 23.6 22.9 26.6 14.0 67.6 15.2 43.3 13.6 23.9 21.5 26.1 12.4 68.8 23.4 83.8 92.1 30.5 8.3 13.1 24.5 15.0 10.7 8.3 50.9 27.0 45.6 48.8 22.2 25.0 32.6 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NOC2L "DKFZP564C186, NET15, NET7, NIR, PPP1R112" ENSG00000188976 "NOC2 like nucleolar associated transcriptional repressor" Q9Y3T9 1 944203-959309 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044258, HPA062195" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044258: AB_10961284, HPA062195: AB_2684707" "unprognostic (3.18e-2)" "unprognostic (5.84e-2)" "unprognostic (1.59e-1)" "unprognostic (9.54e-3)" "unprognostic (6.75e-2)" "unprognostic (2.31e-3)" "unprognostic (1.94e-3)" "unprognostic (1.36e-2)" "unprognostic (1.51e-1)" "unprognostic (2.17e-1)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (6.25e-2)" "unprognostic (3.44e-2)" "unprognostic (1.52e-1)" 26.7 23.6 17.1 23.0 17.1 30.1 26.4 16.8 21.2 29.5 14.3 28.0 17.9 30.3 10.3 47.3 27.7 14.1 32.8 18.1 18.5 27.1 33.7 23.6 23.1 18.5 17.0 26.0 35.6 21.2 24.4 15.8 19.5 26.8 11.6 9.6 26.5 16.0 73.0 45.0 25.2 15.0 15.1 28.0 28.4 36.0 17.6 20.1 24.3 26.4 15.9 32.7 31.7 18.5 112.8 110.4 19.8 129.5 34.5 31.0 70.2 82.3 38.9 114.4 62.1 148.5 110.5 126.3 113.3 56.0 94.0 102.2 147.6 122.8 49.2 79.2 161.5 67.0 141.2 132.0 77.4 151.1 63.8 50.3 35.0 125.3 84.3 35.3 56.4 44.6 190.8 58.2 51.6 182.1 98.7 92.6 112.0 82.3 128.8 120.0 81.5 155.9 53.6 47.4 136.0 133.0 109.3 166.3 105.1 30.3 74.8 81.1 64.1 68.3 95.9 75.2 143.0 97.6 112.5 225.7 84.3 209.1 57.7 21.3 30.9 22.2 23.9 46.4 31.3 23.9 23.3 23.4 36.8 19.3 23.3 18.6 2.8 34.5 57.5 23.6 19.9 31.7 17.1 17.1 16.8 21.2 18.1 18.5 18.5 17.0 19.5 15.1 17.6 18.5 21.5 16.0 23.1 12.4 42.7 69.3 90.8 42.9 47.8 54.6 33.4 34.7 4.5 28.6 29.8 36.8 62.6 63.7 24.7 27.4 17.6 49.9 10.2 34.8 40.9 27.8 30.0 23.8 12.6 46.2 65.5 29.9 28.1 36.9 13.9 36.4 24.7 24.0 39.6 45.4 12.4 27.6 36.7 24.6 29.2 10.3 29.5 24.4 24.9 12.2 35.7 20.6 60.8 9.5 10.6 39.2 21.4 21.4 42.6 71.9 22.9 19.6 27.1 77.0 32.9 41.2 34.6 43.0 83.9 47.4 82.0 58.8 36.6 51.8 53.1 69.3 NOC3L "AD24, C10orf117, FAD24, FLJ12820" ENSG00000173145 "NOC3 like DNA replication regulator" Q8WTT2 10 94333226-94362959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063958, HPA067638, HPA070981" Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063958: AB_2685160, HPA067638: AB_2685876, HPA070981: AB_2686331" "unprognostic (1.29e-1)" "unprognostic (2.25e-1)" "unprognostic (5.25e-2)" "unprognostic (2.49e-1)" "unprognostic (1.27e-3)" "unprognostic (4.58e-2)" "unprognostic (6.49e-3)" "unprognostic (3.34e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-1)" "unprognostic (9.93e-2)" "unprognostic (5.50e-2)" "unprognostic (1.47e-2)" "unprognostic (3.24e-2)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.30e-1)" 8.6 9.0 5.1 9.5 6.5 3.6 11.2 5.9 5.9 6.7 5.9 5.2 5.4 8.5 6.4 9.0 6.2 5.7 5.3 4.6 5.8 7.2 9.9 5.2 13.1 6.5 6.4 8.2 5.3 9.1 4.3 8.9 6.5 7.4 6.3 6.2 5.3 6.5 9.4 9.3 5.4 7.1 6.4 11.4 5.5 10.4 5.8 7.5 11.1 10.4 13.2 10.3 6.4 7.1 38.4 20.6 13.6 44.1 13.9 22.4 16.1 29.9 23.6 40.2 46.3 35.1 26.4 41.3 21.4 15.0 20.6 26.9 39.2 18.0 64.6 28.3 29.3 28.1 16.6 22.6 27.8 45.0 12.2 13.0 17.3 42.5 42.2 26.2 18.1 15.1 44.2 20.3 40.0 12.9 28.5 33.2 28.9 22.3 22.4 12.5 31.3 22.8 23.7 11.7 9.7 24.1 21.4 10.7 33.9 15.2 27.6 17.1 17.7 25.6 25.9 23.4 50.9 19.1 40.8 56.8 23.4 42.6 19.5 0.1 2.6 0.6 4.3 4.3 5.4 14.4 4.4 5.5 4.6 12.8 5.7 5.2 0.1 8.2 5.0 4.1 4.3 3.3 5.1 6.5 5.9 5.9 4.6 5.8 6.5 6.4 6.5 6.4 5.8 7.1 33.5 19.2 13.7 11.4 38.0 23.7 32.7 17.0 33.0 20.7 16.4 20.7 22.5 14.3 31.8 22.0 8.4 21.1 17.7 5.1 25.4 20.6 3.9 20.3 50.1 26.1 5.4 26.7 11.7 13.8 15.1 27.0 10.2 17.0 29.2 26.9 11.7 12.9 13.2 13.5 15.5 8.1 12.2 17.0 11.9 5.0 18.3 15.0 12.4 11.2 23.3 20.5 20.6 19.6 23.6 15.3 3.4 24.8 26.3 34.1 1.7 22.7 21.1 20.9 13.1 37.8 23.7 64.0 64.5 25.5 21.7 15.2 17.3 44.5 10.7 19.1 NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015781-139045939 "Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Glandular and luminal cells: 20.6;Syncytiotrophoblasts: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: AB_2668640, HPA053714: AB_2682238" "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavorable (6.23e-4)" 8.2 2.0 2.8 3.2 2.6 36.3 4.5 1.7 7.1 1.4 0.0 1.8 1.2 1.6 0.5 1.9 1.0 5.5 2.9 5.0 2.9 3.6 13.9 2.9 2.1 1.5 3.4 0.6 3.0 1.7 2.2 5.6 2.6 1.0 1.6 3.4 1.6 0.5 6.5 2.2 2.2 3.0 1.4 1.7 1.7 2.2 4.4 1.9 1.5 6.1 2.6 4.9 1.3 2.9 6.5 7.1 2.9 5.7 6.6 2.7 17.2 9.4 6.9 13.7 10.0 10.3 2.8 22.7 7.4 7.3 18.4 4.5 15.8 8.9 13.7 9.5 6.1 10.3 4.4 8.7 6.2 15.3 6.0 3.2 4.4 15.4 10.4 2.7 6.3 4.3 18.6 7.0 6.6 8.0 10.0 7.8 10.1 3.0 8.1 8.5 8.6 7.7 9.4 4.3 11.3 7.3 6.0 6.8 5.6 11.2 5.0 11.2 8.7 7.7 9.4 7.2 11.8 5.9 5.5 14.0 7.0 29.8 9.9 0.8 0.5 0.3 1.0 0.6 0.5 0.4 0.4 0.5 0.2 0.7 0.3 0.6 2.7 0.6 1.6 0.6 0.3 0.1 2.8 2.6 1.7 7.1 5.0 2.9 1.5 3.4 2.6 1.4 4.4 2.9 10.9 9.6 1.1 0.0 2.8 0.0 2.7 0.0 5.7 5.6 2.7 2.5 0.0 1.5 0.6 0.0 14.6 6.1 4.7 0.6 1.9 2.3 0.7 10.4 6.3 2.6 0.0 1.7 0.0 0.2 11.8 2.9 6.1 20.6 2.5 0.8 1.1 2.6 1.5 1.7 0.0 0.4 0.0 1.6 0.0 0.1 0.9 6.9 0.0 0.0 0.1 0.6 4.1 0.0 0.0 2.5 0.0 0.0 5.5 2.5 2.6 4.0 0.7 5.2 0.0 5.4 4.3 1.0 3.9 6.5 0.0 12.0 4.3 0.8 0.2 2.3 NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" 17.1 29.2 11.3 15.1 12.7 28.7 17.5 12.1 18.0 20.5 9.6 21.3 14.9 15.5 7.9 35.1 16.2 9.0 18.6 11.8 12.3 22.0 16.2 14.3 20.9 12.3 11.8 18.5 17.5 11.5 16.5 8.1 12.1 19.8 9.5 4.9 20.5 4.4 12.6 22.7 19.5 6.6 11.2 26.5 18.8 10.4 11.8 16.1 23.1 8.2 12.6 17.1 23.3 12.9 38.3 33.5 24.4 29.5 8.1 7.8 32.2 17.1 7.7 7.4 8.4 20.0 15.7 30.2 9.8 6.2 8.1 41.4 11.6 50.0 2.2 34.4 51.9 26.3 28.9 43.6 21.3 59.3 38.2 9.6 12.4 31.2 11.7 10.0 15.3 16.7 19.8 26.9 6.8 32.3 36.4 48.0 29.5 16.6 46.7 48.5 16.7 24.7 18.2 10.1 19.2 40.3 22.1 19.5 30.8 2.7 26.9 31.0 22.9 34.2 32.5 24.8 34.5 24.0 29.9 41.0 33.3 46.2 40.0 57.3 24.4 26.9 15.1 28.4 11.7 14.1 14.8 13.6 17.6 15.8 14.8 12.6 53.1 16.7 33.8 13.6 22.3 11.9 11.3 12.7 12.1 18.0 11.8 12.3 12.3 11.8 12.1 11.2 11.8 12.9 10.9 3.2 15.3 4.9 15.3 39.0 13.7 33.0 25.0 11.0 10.2 7.7 3.5 7.2 20.3 14.7 6.2 19.4 11.0 35.6 3.9 25.7 105.7 5.4 5.0 12.9 12.6 8.8 11.4 29.1 16.2 10.2 15.8 4.7 15.2 9.7 10.8 6.2 13.9 28.6 10.9 24.8 20.3 10.7 21.8 48.3 9.9 12.7 21.4 2.8 17.7 13.8 18.6 5.5 8.2 22.4 39.9 11.3 14.0 8.6 27.4 7.8 15.9 8.3 13.1 10.0 10.6 14.5 25.9 45.4 39.8 19.8 14.3 9.7 24.1 14.5 NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: AB_10601274" "unprognostic (8.76e-2)" "unprognostic (8.94e-2)" "unprognostic (8.38e-2)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.64e-5)" "unprognostic (1.26e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-3)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "unprognostic (4.79e-2)" 44.3 43.9 29.5 21.7 30.8 29.5 42.0 32.2 34.0 37.5 28.2 44.8 26.8 37.7 23.4 38.2 35.5 16.6 48.2 28.7 31.1 58.5 37.9 32.2 25.8 30.9 31.4 40.7 48.9 40.2 35.9 21.1 31.0 35.1 19.8 16.6 38.0 19.2 44.5 36.9 36.4 16.0 30.8 37.8 37.9 41.7 30.7 15.2 37.1 17.1 20.3 41.4 34.9 33.8 71.7 37.2 31.7 42.7 26.9 26.1 74.4 71.8 29.3 48.4 44.4 60.0 24.9 97.8 137.4 34.4 57.7 46.5 46.9 42.4 47.8 57.5 105.0 91.2 36.3 104.0 45.4 112.0 61.4 25.5 41.5 42.5 24.2 29.8 33.6 45.5 135.7 22.2 44.7 38.1 70.6 147.6 42.1 37.0 74.1 74.4 46.8 140.5 57.9 21.7 92.5 60.3 40.9 88.0 94.9 36.2 53.6 42.8 65.7 48.0 51.9 57.8 108.3 66.2 123.2 100.2 30.7 70.7 75.6 34.5 59.6 82.1 59.2 76.4 68.2 104.0 84.7 71.4 73.2 87.8 90.7 69.0 27.4 61.9 82.9 91.4 96.0 67.9 29.5 30.8 32.2 34.0 28.7 31.1 30.9 31.4 31.0 30.8 30.7 33.8 103.1 93.0 73.5 10.4 112.5 90.8 117.3 151.0 50.1 62.1 78.9 97.0 214.9 68.6 112.0 57.0 22.9 137.4 71.5 72.7 123.3 188.7 202.3 105.8 95.0 109.2 37.1 89.4 14.0 261.2 153.8 90.9 58.1 91.6 90.6 67.0 61.1 61.8 115.1 48.8 17.1 97.8 130.2 52.6 81.8 38.9 82.6 78.5 101.4 8.4 119.7 124.2 78.2 13.6 19.0 175.0 94.3 79.4 138.8 121.7 81.2 163.6 135.6 61.7 65.7 92.5 119.4 186.3 112.9 70.8 90.5 155.3 99.5 99.2 91.0 117.2 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 106.4 147.2 58.6 96.4 57.7 115.3 109.2 71.5 64.9 116.8 64.4 101.3 86.2 130.2 107.9 111.9 115.4 100.7 81.2 55.3 69.9 103.3 121.5 103.2 136.5 60.3 61.5 197.9 164.8 114.8 97.1 99.1 60.5 97.0 101.2 70.2 106.8 89.6 99.1 112.2 102.0 113.5 59.2 109.5 114.3 55.2 68.5 255.5 116.0 86.1 165.2 116.8 102.6 61.0 421.2 539.7 595.3 344.4 251.2 238.5 345.3 330.9 319.2 459.3 388.5 413.4 312.9 481.4 379.9 320.5 309.7 310.5 949.5 299.4 488.1 383.9 605.7 394.8 498.4 398.0 212.3 547.7 338.7 272.0 206.0 473.1 305.7 370.5 382.0 342.1 535.3 509.0 406.2 413.9 756.0 466.8 771.3 433.9 365.2 660.0 657.3 414.0 345.9 426.1 431.7 519.4 467.8 299.1 392.5 354.9 271.4 354.0 343.9 268.0 438.6 402.9 400.1 297.3 503.2 516.0 216.8 627.1 433.8 107.5 117.3 91.1 107.9 120.0 119.9 107.4 107.9 106.4 118.7 107.2 115.1 115.6 50.8 119.6 140.7 101.1 128.0 178.1 58.6 57.7 71.5 64.9 55.3 69.9 60.3 61.5 60.5 59.2 68.5 61.0 72.9 76.9 81.1 16.3 97.2 126.3 99.9 105.8 116.7 62.3 111.4 83.6 63.5 90.1 99.8 44.1 41.7 132.3 103.6 52.0 56.7 147.8 11.8 81.6 137.8 95.4 139.8 144.6 16.2 111.4 179.9 93.9 71.4 104.8 88.0 135.9 83.9 128.3 112.6 53.8 20.7 105.6 95.6 153.2 107.7 15.9 106.6 95.0 56.9 13.1 132.0 84.8 96.8 19.6 22.8 110.7 75.4 127.9 115.2 94.9 89.0 121.0 71.1 50.3 65.7 78.7 127.8 45.7 66.5 137.3 122.3 130.1 108.5 163.7 117.2 103.0 NOP9 C14orf21 ENSG00000196943 "NOP9 nucleolar protein" Q86U38 14 24299850-24309124 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000850 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "HPA000850: AB_1078287" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (4.57e-3)" "unprognostic (1.85e-1)" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.69e-2)" "unprognostic (9.37e-2)" "unprognostic (7.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (6.77e-2)" "prognostic favorable (9.39e-6)" "unprognostic (7.03e-3)" "unprognostic (3.80e-1)" "unprognostic (1.95e-1)" "unprognostic (1.59e-2)" 9.9 13.0 6.3 5.5 6.7 7.0 9.3 6.2 6.1 8.6 4.6 11.1 7.8 9.9 3.5 16.1 9.5 3.3 13.2 5.8 6.3 8.6 13.8 8.7 6.2 6.7 6.5 11.7 12.6 6.7 7.9 4.1 6.4 9.0 5.5 7.4 10.6 4.4 27.2 12.6 11.4 4.9 6.9 17.3 10.6 7.7 6.8 5.9 8.6 11.2 6.7 9.8 9.3 6.3 6.5 12.8 10.2 12.8 8.7 7.3 9.8 11.4 8.5 13.2 10.2 9.7 11.3 16.7 6.3 10.5 10.7 16.6 20.4 14.2 13.7 10.6 7.8 12.3 18.3 22.4 7.0 28.4 13.5 7.4 10.9 9.7 8.9 7.0 12.4 9.3 10.6 8.0 9.3 11.3 13.2 10.7 4.6 22.9 16.2 16.0 6.1 10.6 8.1 14.8 10.2 7.8 16.1 18.4 3.5 7.3 6.9 7.4 12.8 8.7 7.2 6.9 10.9 11.1 10.6 12.2 4.8 12.7 7.1 0.3 0.6 0.5 0.4 0.7 0.4 0.3 0.3 0.2 0.5 0.4 0.2 0.2 0.1 0.1 1.2 0.3 0.3 0.4 6.3 6.7 6.2 6.1 5.8 6.3 6.7 6.5 6.4 6.9 6.8 6.3 4.0 3.2 3.3 2.6 6.2 12.5 3.2 4.9 6.2 8.1 5.3 3.9 1.2 7.2 8.5 9.2 8.4 6.3 6.7 15.2 0.0 7.3 3.1 5.2 4.8 5.6 10.7 9.9 3.6 10.3 5.8 4.5 6.1 5.0 1.3 9.6 6.1 18.1 7.3 6.7 4.3 7.6 0.0 10.7 6.3 1.3 6.5 5.8 0.0 1.0 7.6 5.5 2.1 3.0 5.0 11.6 8.5 4.5 5.5 5.2 12.5 6.6 7.7 8.0 6.6 5.4 5.4 4.6 5.7 8.1 13.5 6.4 4.9 5.5 14.3 4.6 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NPAP1 C15orf2 ENSG00000185823 "Nuclear pore associated protein 1" Q9NZP6 15 24675775-24683393 "Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;testis: 2.9" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 125.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018828, HPA019562" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA018828: AB_2669941, HPA019562: AB_2670190" "unprognostic (4.40e-2)" "unprognostic (1.85e-2)" "unprognostic (6.98e-3)" "unprognostic (7.45e-2)" "unprognostic (9.90e-2)" "unprognostic (1.08e-2)" "unprognostic (5.11e-3)" 0.0 0.0 0.9 0.0 1.8 0.4 0.1 0.1 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.5 1.7 0.9 0.0 0.0 0.1 0.9 0.7 0.5 0.4 0.0 0.5 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.1 0.1 2.9 1.5 0.0 0.5 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 1.8 0.1 1.1 0.5 1.7 0.9 0.7 0.5 0.5 1.5 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.2 0.7 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 125.9 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 24.1 12.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 33.3;Excitatory neurons: 47.1;Inhibitory neurons: 30.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 2.7;hippocampal formation: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Nuclear bodies, Vesicles" "HPA063852: , HPA065526: AB_2685505" "unprognostic (1.82e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-2)" "unprognostic (7.49e-3)" "unprognostic (9.00e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" 2.7 2.2 1.0 2.3 0.8 3.7 2.7 0.0 2.7 2.9 2.5 2.2 2.1 2.8 2.3 2.0 7.9 2.1 1.9 3.1 0.0 2.2 1.3 3.0 2.3 0.0 0.0 2.9 2.4 2.7 7.8 1.6 0.0 2.2 1.2 2.4 2.2 2.3 2.2 4.9 2.1 2.2 0.0 2.2 2.0 5.3 0.0 2.5 6.7 1.9 1.1 2.1 2.5 0.0 7.8 4.8 5.4 4.3 4.7 6.8 4.1 3.9 3.9 5.3 4.2 4.1 6.5 4.0 9.6 4.6 3.6 7.4 2.7 6.6 2.7 5.1 7.3 3.4 8.1 4.1 3.7 6.5 5.1 5.6 3.2 6.3 3.9 3.4 3.8 9.4 6.2 4.1 2.4 5.9 8.3 7.1 1.0 4.0 5.5 7.1 3.4 6.5 2.6 1.0 17.0 5.5 6.1 4.5 6.5 2.3 6.0 7.2 3.7 7.6 3.2 13.0 4.8 5.0 7.0 4.2 3.4 8.3 2.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 1.0 0.8 0.0 2.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.1 24.2 1.3 4.0 1.2 1.8 3.4 7.3 3.0 3.6 3.1 4.3 3.9 3.7 33.3 0.6 2.2 2.1 1.9 1.6 2.0 10.2 3.3 2.9 3.6 3.2 47.1 1.8 0.5 3.5 4.1 3.0 0.0 4.0 1.8 1.5 2.0 5.0 30.8 2.2 2.0 3.5 3.7 1.4 4.1 2.4 10.6 14.0 1.8 6.3 2.1 10.6 17.3 2.1 2.2 2.2 2.6 1.8 1.1 1.9 10.9 18.2 6.6 1.6 2.7 11.6 6.5 1.9 5.3 1.1 1.7 4.0 1.7 1.1 NPM3 ENSG00000107833 "Nucleophosmin/nucleoplasmin 3" O75607 10 101781325-101783413 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036295, HPA036296" Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoli, Actin filaments, Cytosol" "HPA036295: AB_10671244, HPA036296: AB_10672083" "unprognostic (3.41e-2)" "unprognostic (3.70e-2)" "unprognostic (4.33e-2)" "unprognostic (1.75e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.00e-2)" "unprognostic (1.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.75e-1)" "unprognostic (2.45e-2)" "unprognostic (1.35e-2)" "unprognostic (2.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (5.69e-2)" "unprognostic (9.58e-2)" 12.7 19.5 9.9 18.5 10.2 27.2 19.0 7.8 10.4 19.6 9.6 15.5 8.3 17.2 10.1 26.6 15.3 9.8 8.4 9.6 11.6 16.4 12.3 10.2 23.3 8.4 8.5 20.6 30.3 16.4 12.4 16.3 8.6 13.4 19.3 1.1 15.1 8.2 13.3 16.7 10.7 19.9 8.5 14.8 13.1 17.1 11.6 20.3 11.1 10.1 25.9 20.9 16.7 9.3 94.8 117.2 34.2 226.2 76.5 80.0 36.1 50.0 75.7 75.8 64.4 126.5 117.1 154.8 91.0 56.0 41.6 99.2 192.6 211.8 59.3 66.1 199.8 124.5 50.5 206.0 86.1 286.6 87.4 69.6 100.8 105.2 417.0 39.0 100.6 187.1 156.9 83.7 63.3 173.8 121.0 371.8 60.7 131.1 89.1 93.3 179.2 158.0 75.0 45.8 70.0 45.1 31.2 72.5 144.7 41.8 94.4 59.0 40.1 30.0 95.8 44.8 94.1 36.0 39.9 179.7 41.9 263.4 31.8 0.0 2.8 0.0 3.6 4.0 6.5 4.0 5.9 6.9 6.4 4.8 9.5 9.8 0.1 8.1 0.8 8.3 2.6 5.1 9.9 10.2 7.8 10.4 9.6 11.6 8.4 8.5 8.6 8.5 11.6 9.3 5.1 3.2 5.0 1.0 15.3 62.7 79.6 121.4 28.5 1.4 55.5 54.4 2.9 28.6 32.0 36.8 0.0 91.4 15.6 16.3 78.2 54.0 8.9 7.3 22.1 21.6 24.2 17.9 2.7 41.2 90.6 29.7 13.7 10.5 16.5 19.6 15.0 19.0 68.6 0.0 2.0 33.1 46.8 21.1 69.9 10.9 28.0 18.0 30.2 1.9 14.7 2.5 18.6 1.5 1.0 34.2 12.7 23.7 19.1 118.5 3.1 61.6 16.4 2.0 6.6 47.9 21.6 46.5 91.3 21.3 49.9 60.7 18.5 29.0 46.9 62.8 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 135.8;pituitary gland: 210.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 93.5;Peritubular cells: 326.1;Sertoli cells: 151.2;Spermatocytes: 85.2;Spermatogonia: 94.8" "Cancer enhanced" "Detected in all" "renal cancer: 41.7" "Region enhanced" "Detected in all" "cerebral cortex: 135.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "LHCN-M2: 717.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" NA NA 2490000 360000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: AB_2680889, HPA058320: AB_2732621" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" 7.0 39.2 11.2 1.9 13.6 0.5 3.8 10.1 135.8 9.9 2.5 15.3 0.5 5.7 3.5 3.0 2.8 1.1 9.8 39.2 47.3 1.1 2.6 0.9 0.1 13.8 14.5 3.7 21.4 0.6 210.8 0.1 16.2 7.2 0.8 4.7 3.7 1.6 8.9 8.2 5.4 2.5 6.4 13.0 6.7 34.3 45.6 0.5 3.1 6.7 0.3 5.5 6.9 16.8 0.0 0.0 6.5 0.2 0.0 0.5 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 21.1 2.8 1.5 0.0 0.9 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 717.9 0.0 5.7 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 33.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 13.6 10.1 135.8 39.2 47.3 13.8 14.5 16.2 6.4 45.6 16.8 8.6 0.0 0.6 2.9 0.3 3.8 0.5 0.0 0.0 19.9 0.2 1.4 3.4 5.7 1.3 0.0 4.2 0.0 1.0 4.5 0.0 5.4 12.0 8.5 1.8 16.9 16.0 0.0 22.1 12.8 0.2 11.1 1.5 10.5 0.0 93.5 3.9 0.7 0.5 0.0 5.3 1.2 0.0 0.0 5.4 24.2 14.0 1.3 12.4 5.6 0.0 1.6 0.0 1.0 1.8 2.9 1.1 326.1 1.0 5.2 0.5 0.1 0.0 2.8 151.2 57.2 27.1 85.2 94.8 0.1 3.0 0.1 0.8 12.7 2.3 1.2 NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 280.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Excitatory neurons: 41.7;Inhibitory neurons: 50.4;Oligodendrocyte precursor cells: 19.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 23.3;SCLC-21H: 30.8;SiHa: 23.6;U-87 MG: 87.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 420000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: AB_1078414" "unprognostic (6.29e-2)" "prognostic favorable (3.93e-4)" "unprognostic (6.82e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.55e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-3)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-2)" "unprognostic (9.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.77e-2)" 2.7 5.0 91.6 1.9 75.4 0.3 2.8 0.3 145.7 8.7 0.0 9.5 1.3 10.9 3.8 3.0 7.9 2.0 15.7 280.2 17.0 1.6 1.9 1.9 1.6 4.1 15.2 8.1 5.2 7.0 6.8 0.4 0.7 8.1 1.5 5.3 4.8 7.0 0.6 1.1 3.3 7.6 3.1 2.5 5.0 1.8 58.0 0.7 2.7 2.5 1.5 7.3 4.8 46.0 1.0 6.2 0.2 1.8 12.2 1.2 0.0 4.1 0.9 7.9 2.7 6.2 1.3 0.0 7.2 1.1 23.3 0.8 1.7 0.2 2.6 0.6 2.0 0.0 0.2 9.6 1.2 0.1 0.3 3.9 0.4 7.2 0.1 11.4 0.3 0.1 7.7 0.3 0.3 9.7 0.0 0.5 7.3 3.0 2.2 1.6 0.0 15.3 2.0 17.1 30.8 2.0 23.6 0.1 0.7 1.7 9.9 2.5 0.4 14.1 8.4 0.0 0.7 2.1 0.0 0.0 87.9 18.5 7.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 91.6 75.4 0.3 145.7 280.2 17.0 4.1 15.2 0.7 3.1 58.0 46.0 4.7 0.0 0.0 9.4 0.3 1.1 2.7 0.9 0.0 6.6 3.3 1.5 18.0 4.3 3.0 3.7 2.1 0.0 2.3 0.0 0.0 7.3 1.7 1.7 3.2 4.2 1.8 0.0 41.7 3.8 0.0 1.5 0.5 3.0 0.0 1.5 5.0 0.4 0.2 0.0 50.4 0.2 6.1 0.3 0.9 0.8 1.8 0.3 1.8 1.9 0.0 4.8 6.2 19.1 10.5 2.0 0.0 2.2 0.9 3.8 0.1 0.5 2.2 3.3 0.0 2.4 2.8 0.2 1.3 0.1 1.0 0.0 1.7 0.3 0.0 3.4 NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 32.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 5.4;Ionocytes: 8.2;monocytes: 2.6;Oligodendrocyte precursor cells: 10.6;Theca cells: 4.9" "Cancer enhanced" "Detected in many" "lung cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 62.5;RT4: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: AB_2732673, HPA067207: AB_2732761" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" "unprognostic (9.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.45e-3)" "unprognostic (4.83e-2)" "unprognostic (9.00e-2)" "unprognostic (1.33e-3)" 0.2 32.7 1.4 0.0 1.3 0.0 0.2 1.0 1.5 2.4 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 1.4 1.3 3.6 2.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.7 19.3 5.9 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 62.5 0.0 0.0 2.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 1.0 1.5 1.3 1.8 1.4 1.3 1.3 1.2 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 8.2 0.0 0.0 1.9 1.2 0.1 1.8 0.0 2.6 0.0 0.0 10.6 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.8 0.0 0.1 0.0 0.0 4.9 0.0 0.1 NR2C1 "TR2, TR2-11" ENSG00000120798 "Nuclear receptor subfamily 2 group C member 1" P13056 12 95020229-95073628 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035040, HPA035041, HPA067767" Supported Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cell Junctions, Cytosol" "HPA035040: AB_2674426, HPA035041: AB_2674427, HPA067767: AB_2685898" "unprognostic (2.44e-1)" "unprognostic (8.04e-3)" "unprognostic (3.17e-2)" "unprognostic (2.51e-1)" "unprognostic (3.56e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (5.18e-5)" "unprognostic (1.30e-2)" "unprognostic (1.29e-2)" "unprognostic (1.86e-1)" "unprognostic (3.83e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (2.31e-1)" "unprognostic (1.42e-1)" "unprognostic (2.16e-1)" "prognostic favorable (5.62e-5)" 8.3 10.4 4.9 5.0 5.6 9.3 7.7 14.0 9.3 9.3 8.2 8.6 5.6 10.3 9.9 5.4 10.2 4.4 10.0 5.1 5.1 6.6 10.0 8.6 5.5 4.7 4.9 9.9 8.2 6.1 7.2 5.8 5.6 6.7 6.2 15.6 5.2 7.5 14.3 6.1 7.6 7.8 4.6 9.2 6.1 11.9 5.6 5.7 11.9 5.5 5.3 8.1 7.4 6.9 11.4 13.9 23.0 10.2 5.8 10.0 30.5 10.9 7.9 10.6 9.9 12.2 6.2 13.8 3.8 7.3 6.8 11.8 10.7 8.6 8.1 6.0 23.1 16.7 11.5 15.4 11.1 11.3 7.0 10.2 7.0 7.9 9.5 13.3 11.6 16.8 12.9 5.2 12.9 8.3 12.4 26.0 14.5 9.1 24.0 11.7 15.0 8.1 12.3 13.9 11.1 8.8 17.6 7.4 8.4 11.8 12.9 7.5 10.9 8.6 8.4 10.7 6.2 7.7 13.1 13.0 2.1 13.0 4.2 0.3 2.4 2.1 3.9 2.6 5.0 2.0 3.1 3.3 3.7 2.3 4.0 2.8 1.5 2.1 2.3 3.6 2.3 2.3 4.9 5.6 14.0 9.3 5.1 5.1 4.7 4.9 5.6 4.6 5.6 6.9 18.7 35.3 15.4 28.4 14.4 8.3 14.4 7.8 15.4 44.8 7.6 7.5 18.5 8.6 5.6 11.0 18.8 15.3 19.9 10.3 3.9 11.6 25.2 14.8 23.3 15.5 7.2 15.6 55.4 9.4 12.7 17.4 16.3 18.8 10.1 28.0 13.2 12.7 9.5 25.2 73.4 11.4 12.2 11.1 9.5 6.4 43.8 10.9 14.2 34.7 10.7 14.9 12.3 26.2 51.1 18.7 9.9 30.1 13.7 9.4 5.8 8.1 19.6 49.6 6.6 17.3 14.6 67.0 25.9 12.1 7.4 7.8 15.0 18.0 13.3 20.2 NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 411.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB010435: AB_2155784, HPA004248: AB_1078976" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.74e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.15e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.06e-3)" "unprognostic (1.02e-1)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" 35.3 11.8 15.2 22.6 18.1 49.4 25.5 34.0 24.7 19.7 18.2 13.7 19.2 18.8 13.6 25.7 18.8 21.1 24.2 14.9 25.0 19.2 39.8 31.9 25.6 18.1 14.9 21.1 14.7 33.8 16.2 46.9 16.1 19.7 14.5 9.5 16.1 20.0 45.0 20.4 18.0 23.8 15.0 24.5 16.0 11.1 21.6 40.0 25.6 40.1 27.3 18.2 16.0 28.5 30.4 60.6 4.4 0.1 38.2 42.3 5.2 46.5 55.3 39.3 45.1 4.5 39.7 26.8 20.8 68.6 46.0 28.1 0.3 36.6 48.3 15.2 21.0 6.9 77.0 13.5 35.7 28.1 20.6 30.8 46.3 64.7 62.5 49.0 15.0 12.1 10.3 98.8 35.1 10.9 16.7 20.0 11.9 5.1 13.0 6.0 41.4 58.0 11.5 2.1 8.0 6.1 81.3 11.7 19.4 4.9 5.3 39.8 35.8 94.7 18.7 45.7 35.9 20.1 19.7 41.5 49.7 28.5 33.6 67.4 21.3 38.9 18.3 24.2 15.1 15.9 18.6 17.9 28.5 22.3 17.8 17.2 68.4 23.1 23.6 25.9 12.8 17.3 15.2 18.1 34.0 24.7 14.9 25.0 18.1 14.9 16.1 15.0 21.6 28.5 152.3 67.3 69.1 71.2 134.1 58.8 35.9 37.9 79.6 13.1 39.0 55.8 43.4 57.2 41.2 25.8 16.7 48.9 158.3 22.9 17.6 30.8 165.6 8.1 30.1 82.3 28.1 55.9 411.4 33.3 39.5 112.2 23.9 10.4 89.3 7.5 63.5 193.9 53.2 37.0 169.5 4.1 10.2 66.3 99.2 144.1 63.0 97.4 53.4 241.7 87.6 34.6 83.4 240.3 237.5 35.9 17.9 71.5 115.1 46.2 25.3 67.9 37.9 65.0 151.2 181.9 105.0 24.5 40.1 57.4 56.3 36.5 204.5 12.6 12.9 14.3 NR4A1 "GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3" ENSG00000123358 "Nuclear receptor subfamily 4 group A member 1" P22736 12 52022832-52059507 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 879.9;Basal squamous epithelial cells: 729.1;Glandular and luminal cells: 739.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 36.7;non-classical monocyte: 54.2" "Lineage enriched" "Detected in many" 15 "monocytes: 54.2" "Cell line enhanced" "Detected in many" "HeLa: 78.4;MCF7: 86.9;SK-BR-3: 80.5;SK-MEL-30: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059742, HPA070142" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear membrane, Cytosol" "HPA059742: AB_2684119, HPA070142: AB_2732149" "unprognostic (2.40e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "unprognostic (1.74e-1)" "unprognostic (1.65e-1)" "unprognostic (1.16e-1)" "unprognostic (1.26e-2)" "unprognostic (1.94e-1)" "unprognostic (1.92e-2)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "prognostic favorable (6.99e-4)" "unprognostic (3.41e-2)" "unprognostic (2.71e-1)" "unprognostic (1.84e-2)" "unprognostic (8.89e-3)" 709.0 562.0 21.7 96.9 19.6 34.5 227.6 141.0 79.9 151.6 44.4 227.1 29.7 124.6 7.2 133.6 495.8 377.4 671.5 21.5 28.5 203.5 95.5 290.9 45.9 21.8 17.4 876.0 88.4 86.9 442.4 41.9 21.0 303.2 71.4 28.3 146.5 85.9 294.1 225.7 111.9 144.2 13.0 36.0 264.6 32.4 21.5 59.1 301.7 71.9 3.8 296.5 186.0 22.6 5.7 28.2 5.6 10.2 4.0 1.3 21.3 5.4 10.8 4.3 6.0 28.2 5.4 5.9 2.3 9.7 4.2 3.2 16.9 2.6 2.5 0.3 6.0 8.1 78.4 8.3 4.1 3.1 26.5 0.8 3.3 4.2 0.3 2.9 1.3 6.6 7.9 1.4 0.3 86.9 2.2 8.5 15.3 9.2 3.1 2.7 0.9 14.6 0.2 2.2 4.6 14.0 17.4 80.5 150.9 3.8 5.1 9.1 0.0 4.2 13.3 2.8 4.7 46.8 25.2 13.0 2.8 2.3 23.7 0.3 1.3 0.0 0.2 36.7 0.3 0.9 0.1 0.1 3.7 0.8 0.5 0.1 0.4 0.2 54.2 0.3 0.2 2.0 21.7 19.6 141.0 79.9 21.5 28.5 21.8 17.4 21.0 13.0 21.5 22.6 328.9 240.4 879.9 4.2 259.5 445.7 289.5 211.3 729.1 34.8 353.8 384.9 9.8 65.8 178.4 86.5 125.1 64.5 102.1 195.7 5.9 19.9 19.7 346.9 183.5 209.6 345.3 16.0 17.4 12.3 34.7 378.8 380.7 739.1 674.8 45.3 227.0 10.1 54.1 16.8 5.9 492.5 105.8 64.4 527.4 7.3 30.4 283.0 371.8 8.4 6.3 85.4 0.0 6.6 1.3 5.1 277.2 23.7 244.1 160.6 74.6 0.9 92.6 94.6 124.9 268.0 379.3 2.5 13.4 200.2 472.8 110.5 135.1 85.1 259.0 86.8 NR6A1 "CT150, GCNF, GCNF1, RTR" ENSG00000148200 "Nuclear receptor subfamily 6 group A member 1" Q15406 9 124517275-124771311 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.5;Extravillous trophoblasts: 160.0;Inhibitory neurons: 114.7;Oligodendrocyte precursor cells: 112.6;Spermatogonia: 111.1" "Cancer enriched" "Detected in many" 16 "testis cancer: 27.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.2;neutrophil: 4.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.9" "Cell line enhanced" "Detected in many" "BEWO: 110.7;CACO-2: 26.5;Hep G2: 25.8;K-562: 34.1;NTERA-2: 39.2;U-266/84: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031461, HPA045145" Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Centrosome, Cytosol" "HPA031461: AB_2673894, HPA045145: AB_2679233" "unprognostic (1.73e-1)" "unprognostic (6.66e-2)" "unprognostic (4.53e-1)" "unprognostic (1.34e-6)" "unprognostic (4.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.52e-5)" "unprognostic (6.31e-2)" "unprognostic (8.01e-3)" "unprognostic (2.71e-2)" "unprognostic (1.58e-2)" "unprognostic (1.63e-1)" "unprognostic (7.26e-2)" "unprognostic (7.20e-3)" "unprognostic (1.71e-1)" "unprognostic (6.77e-3)" "unprognostic (1.09e-1)" 0.3 0.8 1.8 0.9 1.9 4.4 0.9 2.2 1.9 0.8 4.5 2.2 1.7 0.5 0.5 1.9 0.5 0.4 1.0 1.8 1.5 1.7 2.7 1.5 0.3 2.0 1.5 0.3 2.9 0.8 1.4 2.3 1.5 1.4 1.5 3.1 1.2 0.5 1.4 2.2 2.5 0.4 1.4 0.8 0.4 22.9 3.4 0.1 5.4 0.8 0.7 0.7 1.3 1.6 1.2 3.0 14.7 2.0 0.3 0.2 110.7 0.2 1.1 0.8 1.3 26.5 2.9 5.0 1.0 0.1 3.8 2.8 1.6 1.3 1.7 1.1 4.6 4.1 4.8 25.8 0.1 2.3 7.2 0.1 1.3 1.2 1.6 0.3 0.2 1.2 34.1 0.7 0.6 0.6 0.1 3.2 39.2 1.3 1.1 1.2 1.5 2.2 0.5 2.0 2.2 0.8 0.2 0.7 0.9 21.7 2.6 1.3 0.0 1.4 3.1 0.9 0.7 3.3 25.0 4.3 0.9 2.3 0.8 0.0 0.6 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 4.9 0.0 0.3 0.1 0.0 0.1 1.8 1.9 2.2 1.9 1.8 1.5 2.0 1.5 1.5 1.4 3.4 1.6 0.8 0.0 7.7 47.0 0.6 37.3 17.4 4.2 13.6 3.8 6.8 3.7 2.0 7.2 5.9 5.5 29.2 36.7 1.6 8.9 1.9 10.1 53.5 4.1 0.9 3.2 4.8 6.1 105.5 3.5 160.0 2.0 2.0 3.7 1.3 16.1 1.4 6.0 8.2 1.7 114.7 6.9 8.2 2.2 30.6 30.3 1.2 3.2 8.8 54.4 5.2 7.0 0.0 112.6 73.0 1.9 6.0 1.9 0.5 19.4 24.5 3.3 8.6 10.7 0.0 1.5 3.5 72.7 111.1 8.6 39.8 30.6 0.3 8.1 11.9 15.5 NRAP ENSG00000197893 "Nebulin related anchoring protein" Q86VF7 10 113588714-113664070 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 2363.9;tongue: 1144.8" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 534.1" "Group enriched" "Detected in some" 7 "head and neck cancer: 8.2;prostate cancer: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037953, HPA037954, HPA075074" Enhanced Approved "Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "Vesicles, Cytosol" "HPA037953: AB_2675755, HPA037954: AB_10672394, HPA075074: " "unprognostic (1.13e-1)" "unprognostic (2.95e-1)" "unprognostic (3.61e-2)" "unprognostic (2.05e-2)" "unprognostic (5.75e-2)" "unprognostic (1.97e-2)" "unprognostic (1.25e-2)" "unprognostic (3.03e-3)" "unprognostic (3.72e-2)" "unprognostic (4.20e-2)" "unprognostic (6.40e-2)" "unprognostic (2.88e-1)" "unprognostic (5.39e-4)" "unprognostic (8.21e-2)" "unprognostic (1.16e-1)" "unprognostic (3.16e-1)" 0.3 0.1 0.1 0.0 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 24.8 0.0 0.2 428.6 0.2 0.0 0.1 0.5 0.4 0.1 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 20.4 1.0 0.0 22.1 0.0 2363.9 0.8 0.1 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.4 1144.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 534.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.4 0.1 0.0 3.7 0.0 0.0 0.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 4.8 0.0 0.0 0.3 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 57.3 3.3 1.0 2.3 0.0 0.1 0.0 0.2 0.0 0.5 0.0 NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 37.3;brain: 38.3;epididymis: 34.4;retina: 38.0" "Group enriched" "Detected in many" 7 "Astrocytes: 612.5;Excitatory neurons: 764.5;Inhibitory neurons: 392.4;Oligodendrocyte precursor cells: 1259.2" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 15 "T-cells: 2.0" "Cell line enhanced" "Detected in many" "A549: 99.6;AF22: 94.8;EFO-21: 175.4;HMC-1: 187.9;SH-SY5Y: 115.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" NA NA 110000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" 3.1 37.3 19.8 1.8 31.9 0.3 1.5 2.4 34.6 5.0 0.0 0.8 0.7 2.1 34.4 0.7 3.6 7.3 0.4 33.1 9.4 6.2 0.4 2.3 0.8 2.3 22.7 1.5 29.4 7.3 11.4 7.8 2.0 0.8 0.7 38.0 1.9 14.2 0.2 0.8 0.6 0.7 1.5 4.8 1.8 1.7 38.3 2.8 4.1 0.4 2.7 0.5 0.4 2.6 0.1 99.6 94.8 0.0 11.4 2.2 1.8 0.7 0.4 1.0 1.7 40.7 0.0 0.0 175.4 0.7 1.5 0.4 2.2 1.6 1.0 0.1 12.7 0.0 0.7 1.0 0.2 0.9 187.9 15.5 0.0 0.2 0.6 0.2 61.7 0.2 0.2 0.8 1.5 38.2 0.4 0.3 13.1 60.1 0.0 0.0 27.8 33.3 21.4 0.1 18.6 115.9 1.3 0.0 1.9 3.3 0.2 0.1 66.2 4.2 1.0 0.1 16.4 0.2 0.5 0.9 0.7 0.1 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.2 19.8 31.9 2.4 34.6 33.1 9.4 2.3 22.7 2.0 1.5 38.3 2.6 0.2 0.0 0.0 612.5 0.8 0.4 0.1 0.8 1.2 66.2 1.5 0.9 0.7 7.2 0.1 5.5 102.2 3.6 0.0 0.2 3.9 1.6 37.3 10.4 2.4 1.3 0.0 0.0 764.5 12.1 0.2 2.0 3.6 25.0 23.4 4.4 1.4 0.4 0.8 13.5 392.4 0.3 0.0 0.8 0.4 8.3 0.9 0.2 3.6 51.5 0.6 45.1 0.0 1259.2 21.9 3.7 0.0 0.4 2.6 1.2 0.0 3.3 0.1 8.8 0.0 1.0 2.6 1.1 2.7 0.2 0.1 4.4 1.1 34.2 0.0 0.0 NRIP1 RIP140 ENSG00000180530 "Nuclear receptor interacting protein 1" P48552 21 14961235-15065936 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029785, HPA046571, HPA060036" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" Cytosol "HPA029785: , HPA046571: AB_2679704, HPA060036: AB_2684193" "unprognostic (5.60e-2)" "unprognostic (1.87e-1)" "unprognostic (5.20e-3)" "unprognostic (4.64e-3)" "unprognostic (7.98e-2)" "unprognostic (2.59e-2)" "unprognostic (2.74e-1)" "unprognostic (2.75e-3)" "unprognostic (8.94e-3)" "unprognostic (1.55e-1)" "unprognostic (2.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-2)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (2.72e-1)" "unprognostic (2.80e-1)" 30.4 10.2 5.8 10.2 5.2 26.4 14.2 14.9 6.9 24.7 6.5 18.2 16.8 18.2 13.4 9.4 21.4 10.3 5.4 6.4 8.1 15.9 26.9 8.9 8.7 4.8 4.5 13.3 14.4 7.4 3.2 14.6 5.3 10.3 18.1 31.8 6.1 8.4 22.3 4.1 18.3 20.1 6.4 13.1 8.9 8.1 6.7 17.0 5.6 23.8 7.2 14.1 8.4 8.3 22.1 43.5 34.6 0.0 17.4 11.3 12.6 26.1 11.7 16.0 12.5 8.7 17.3 0.1 14.5 23.3 7.9 11.0 2.2 15.6 33.9 0.0 10.0 33.4 15.3 27.2 10.5 16.7 6.7 14.1 21.3 17.6 20.5 17.8 12.6 4.8 24.1 17.4 11.4 11.8 7.8 0.1 14.5 8.8 13.9 92.4 28.0 0.8 9.8 35.8 3.2 0.1 21.7 11.3 8.8 27.7 27.2 12.9 22.0 13.7 9.1 21.4 10.8 8.5 0.2 0.1 29.0 0.0 6.8 0.0 0.4 0.2 0.3 0.2 1.8 0.3 0.3 0.4 0.6 1.0 0.5 0.2 0.1 0.5 0.5 0.6 0.2 0.2 5.8 5.2 14.9 6.9 6.4 8.1 4.8 4.5 5.3 6.4 6.7 8.3 33.2 48.1 37.6 60.7 27.4 18.6 122.6 16.2 22.8 33.9 52.9 26.8 18.3 21.5 40.9 29.5 50.1 16.4 20.7 50.1 9.8 23.0 15.8 60.9 99.1 43.0 37.7 24.2 123.7 27.6 120.8 42.3 26.5 130.9 31.5 94.0 27.1 44.7 45.7 21.9 95.0 41.6 18.3 50.4 21.9 19.3 37.6 57.9 8.8 219.2 40.4 56.2 27.8 102.1 78.2 31.4 42.6 27.1 10.1 49.5 43.0 36.5 15.9 63.1 32.9 112.1 38.6 12.1 6.3 23.1 18.8 14.1 19.9 71.0 47.7 99.8 NRIP2 DKFZP761G1913 ENSG00000053702 "Nuclear receptor interacting protein 2" Q9BQI9 12 2825348-2835544 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Rod photoreceptor cells: 8.8;Sertoli cells: 26.3;Smooth muscle cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039197, HPA039860" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039197: AB_10673416, HPA039860: AB_10794203" "unprognostic (3.28e-3)" "unprognostic (3.83e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (2.10e-2)" "unprognostic (8.11e-2)" "unprognostic (4.26e-3)" "unprognostic (5.66e-2)" "unprognostic (4.42e-3)" "unprognostic (2.89e-1)" "unprognostic (4.39e-2)" "prognostic favorable (8.69e-5)" "unprognostic (7.15e-2)" "unprognostic (2.82e-2)" "unprognostic (7.55e-2)" "unprognostic (5.23e-2)" "unprognostic (1.00e-1)" "unprognostic (8.97e-2)" 5.4 3.9 7.7 3.6 12.4 4.0 5.1 23.4 10.2 7.0 4.8 5.3 2.4 7.4 7.2 2.4 4.8 5.9 5.2 5.8 10.6 12.0 1.6 1.8 4.1 12.4 10.0 8.4 3.0 0.6 2.8 2.6 12.9 4.1 3.0 3.9 3.6 4.9 4.9 2.6 4.7 4.9 8.1 9.1 3.6 2.1 12.0 3.0 5.5 7.5 2.6 4.3 4.7 13.3 0.4 0.9 1.5 0.8 0.0 0.0 1.8 1.1 0.0 0.0 0.0 2.3 1.1 1.2 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.9 1.3 2.0 2.9 0.2 0.0 2.4 1.4 0.0 0.0 0.0 0.0 2.2 0.0 1.3 1.1 2.7 0.0 1.0 1.5 1.2 1.5 0.9 0.4 0.9 1.6 0.7 0.0 1.5 1.1 1.7 0.8 1.2 0.3 2.7 0.8 0.4 1.2 0.6 0.7 0.9 1.6 0.4 0.1 1.8 1.5 1.1 0.8 3.7 0.3 0.1 0.5 0.2 0.3 0.7 0.4 0.5 0.2 0.6 0.8 0.3 0.1 0.4 0.1 0.3 0.1 0.1 7.7 12.4 23.4 10.2 5.8 10.6 12.4 10.0 12.9 8.1 12.0 13.3 0.6 0.0 1.1 0.0 0.2 0.1 0.5 0.0 0.0 5.0 0.1 0.9 1.3 0.0 0.0 1.8 6.2 0.3 0.3 0.0 0.0 0.0 1.6 0.2 0.9 0.6 0.0 0.0 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.4 0.0 0.1 3.3 3.3 0.0 0.0 0.6 0.3 1.8 0.3 0.5 0.0 2.8 0.0 0.6 3.1 0.5 4.9 0.0 0.0 5.3 0.0 0.3 0.0 0.2 0.0 8.8 26.3 0.5 23.1 0.1 0.3 0.1 0.1 0.0 1.1 0.4 0.0 0.1 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NRSN2 "C20orf98, dJ1103G7.6" ENSG00000125841 "Neurensin 2" Q9GZP1 20 346782-359660 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 154.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015967 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Nucleoplasm, Cytosol" "HPA015967: AB_1854647" "unprognostic (5.67e-2)" "unprognostic (3.47e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (4.05e-2)" "unprognostic (4.48e-2)" "unprognostic (1.48e-1)" "unprognostic (4.96e-2)" "unprognostic (5.92e-2)" "prognostic favorable (1.61e-4)" "unprognostic (6.96e-2)" "unprognostic (1.96e-3)" "unprognostic (2.94e-2)" "unprognostic (1.96e-1)" "unprognostic (7.85e-3)" "unprognostic (1.73e-3)" 19.9 57.0 105.7 10.5 114.4 1.7 17.4 87.8 154.7 30.1 71.3 28.3 6.0 32.5 25.9 9.7 27.9 15.4 30.9 114.3 100.6 33.0 4.8 22.4 7.5 94.4 92.0 36.0 20.3 42.6 60.4 16.9 93.9 28.3 9.7 56.9 21.1 25.5 3.4 11.4 13.1 27.5 80.5 16.8 20.2 30.6 96.6 5.5 28.1 5.7 7.2 23.5 18.2 102.9 56.5 68.3 40.2 37.7 53.0 58.4 15.2 37.4 72.3 66.3 66.8 38.2 1.2 0.0 12.6 70.7 48.9 24.1 33.5 5.8 42.4 0.3 33.0 20.8 32.5 70.7 53.5 0.6 3.3 67.4 4.5 48.2 8.1 54.1 46.4 0.3 40.3 35.1 59.2 10.0 0.9 17.9 31.3 0.7 34.9 32.4 22.1 2.7 67.4 0.3 80.8 58.0 44.9 13.0 64.9 26.5 53.2 19.7 31.0 70.6 36.4 2.6 45.6 6.5 1.4 14.7 9.5 0.6 36.7 0.0 0.7 1.2 2.4 0.3 0.7 5.6 0.8 2.6 1.5 6.9 1.0 1.8 0.0 2.8 0.3 3.5 0.6 1.1 105.7 114.4 87.8 154.7 114.3 100.6 94.4 92.0 93.9 80.5 96.6 102.9 3.8 0.0 3.1 16.0 2.2 3.2 3.6 8.5 7.4 26.5 5.8 5.0 5.5 1.5 6.1 12.9 2.1 7.3 0.5 2.6 1.9 14.7 9.6 4.7 12.0 6.9 29.4 1.3 21.0 1.6 6.8 10.4 3.1 3.9 5.1 7.6 5.7 0.3 3.2 16.8 27.1 2.6 4.1 0.9 2.2 14.4 13.1 0.7 3.6 2.8 2.1 17.3 2.1 12.1 5.9 2.9 1.8 10.5 2.6 3.3 0.2 7.8 3.6 15.4 19.7 4.9 9.2 21.3 12.8 1.4 2.3 4.4 1.4 12.9 2.2 2.9 NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 1900000 "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: AB_2679935, HPA050628: AB_2681194" "unprognostic (7.55e-2)" "unprognostic (5.26e-2)" "unprognostic (2.51e-2)" "unprognostic (2.47e-1)" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (2.58e-1)" "unprognostic (4.97e-2)" "unprognostic (6.90e-2)" "unprognostic (5.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.44e-2)" "unprognostic (7.50e-3)" 22.8 37.7 38.3 13.5 39.5 27.8 21.5 37.0 45.9 23.2 41.6 23.0 14.9 22.5 26.8 28.5 26.1 13.5 29.1 39.7 38.6 21.4 26.3 18.0 15.2 39.0 39.0 25.7 15.5 23.9 14.1 21.1 39.8 20.9 18.4 22.6 19.3 26.4 69.0 36.6 17.6 22.9 36.4 19.8 18.0 14.8 38.6 21.0 20.0 43.3 18.6 22.4 21.6 39.7 55.6 64.4 35.9 32.0 30.5 31.4 28.7 21.0 41.8 57.7 41.3 53.9 43.1 31.6 16.6 47.8 47.2 50.4 25.9 70.3 40.8 12.3 25.1 29.8 10.3 61.4 33.8 30.7 16.4 23.5 33.3 55.3 20.3 30.8 46.8 23.4 42.5 26.5 36.2 29.1 31.4 54.7 40.7 42.5 65.4 14.7 41.1 29.8 68.6 37.1 20.5 23.4 29.6 59.8 26.7 18.8 36.5 22.0 37.8 38.7 29.4 23.9 40.2 21.9 41.8 24.7 28.9 43.0 29.3 31.4 21.3 80.3 20.0 26.6 19.7 35.0 21.2 19.5 29.7 36.0 23.4 20.7 69.1 16.7 28.1 23.1 28.2 25.5 38.3 39.5 37.0 45.9 39.7 38.6 39.0 39.0 39.8 36.4 38.6 39.7 34.6 22.4 23.2 17.3 36.1 89.2 63.5 106.3 44.3 60.2 28.6 26.0 35.4 24.3 57.8 31.3 22.9 150.7 29.7 68.2 56.7 104.7 23.0 51.0 29.6 44.3 43.6 41.0 24.0 94.5 146.0 41.1 30.5 54.9 40.5 49.1 31.1 42.2 81.1 70.7 24.8 42.5 61.1 43.7 43.6 38.8 39.1 43.8 42.7 14.0 52.9 61.7 32.0 17.6 31.2 123.4 65.7 46.3 41.8 76.0 66.4 73.8 43.2 44.5 78.9 44.2 64.7 106.1 103.2 55.1 75.7 151.6 31.6 48.9 44.0 88.5 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 35.5" "Group enriched" "Detected in some" 29 "Early spermatids: 159.5;Late spermatids: 300.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Plasma membrane" Nucleoplasm "HPA056683: AB_2683207" "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.5 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.1 2.6 0.1 0.7 0.1 0.0 1.0 0.1 0.7 0.6 0.1 0.1 0.3 0.2 0.2 0.3 0.3 0.5 0.0 0.4 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.2 0.0 0.0 1.1 0.2 0.0 0.1 0.2 0.8 35.5 0.4 0.0 0.7 0.0 0.0 0.3 0.1 0.2 1.2 0.2 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 1.2 0.5 0.1 0.0 0.7 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.4 0.1 0.0 1.0 0.0 0.1 0.2 0.2 0.6 0.1 0.2 0.3 0.0 1.1 0.8 0.4 0.9 0.1 0.5 0.1 0.2 0.2 0.6 0.5 0.3 1.0 0.1 0.3 0.2 0.7 0.9 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.4 0.4 0.1 0.3 0.8 0.7 0.0 0.2 0.0 1.2 0.1 0.1 0.2 0.3 0.2 0.2 0.1 0.1 0.3 0.5 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 159.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 300.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5C1B-RDH14 ENSG00000250741 "NT5C1B-RDH14 readthrough" 2 18555545-18589564 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 126 "testis: 16.6" "Group enriched" "Detected in some" 97 "Early spermatids: 52.3;Late spermatids: 64.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Plasma membrane" Nucleoplasm "HPA056683: AB_2683207" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014114-33062797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 191.0;Paneth cells: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.4 14.3 11.4 26.1 11.4 32.6 21.3 15.2 15.6 12.6 10.8 51.9 40.0 16.9 14.3 18.6 15.9 23.4 16.6 11.5 11.5 22.4 11.8 17.6 30.8 11.1 11.8 13.4 21.4 9.7 7.5 16.3 11.5 12.3 51.0 20.4 9.7 10.0 87.4 28.7 37.3 13.2 12.7 22.9 27.0 9.5 12.0 22.5 17.1 51.0 45.8 23.8 14.4 13.1 42.2 27.6 25.2 29.6 21.2 16.1 20.3 44.8 30.5 29.2 38.9 19.9 115.1 100.4 27.7 29.6 48.3 63.8 28.3 30.8 40.4 16.2 36.2 54.7 36.5 28.7 23.3 55.6 36.9 21.7 23.8 35.9 63.0 16.4 22.2 33.2 43.3 24.8 37.3 29.9 25.0 87.8 27.8 47.1 31.2 25.9 22.9 60.0 87.8 39.8 28.1 37.0 31.1 52.4 66.6 24.5 35.2 33.5 19.8 25.1 20.9 42.6 55.7 50.6 69.0 54.8 20.6 34.9 42.5 112.5 25.9 82.5 26.6 32.7 30.6 64.0 34.2 30.8 22.1 63.6 34.5 29.1 103.8 28.2 39.2 20.6 56.2 37.9 11.4 11.4 15.2 15.6 11.5 11.5 11.1 11.8 11.5 12.7 12.0 13.1 39.1 22.4 13.7 30.7 85.1 46.8 40.9 85.3 47.8 23.9 22.6 18.9 16.9 32.9 40.4 16.5 41.7 36.9 42.5 191.0 29.4 34.4 5.7 40.9 21.0 40.8 119.6 127.1 45.3 79.0 31.6 35.2 42.8 21.4 17.7 38.3 30.0 18.9 25.0 1.7 49.4 98.9 40.7 31.2 23.5 5.0 33.8 111.4 26.6 29.0 37.0 23.4 55.6 48.2 52.4 48.3 186.6 22.2 43.8 45.7 91.8 84.8 53.7 27.1 13.1 30.7 24.9 46.4 24.0 35.5 38.9 28.3 53.7 23.3 71.0 65.9 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 239.3;Early spermatids: 119.6;Excitatory neurons: 360.0;Inhibitory neurons: 277.8;Late spermatids: 148.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 499.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-138 MG: 100.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 12.8 3.7 31.3 0.8 33.2 0.1 7.8 30.7 34.3 12.8 0.0 3.4 0.5 10.4 3.2 1.3 15.0 1.6 5.8 38.8 25.8 5.1 1.0 5.3 1.2 21.5 19.6 7.2 1.0 0.1 12.2 1.0 22.1 9.0 2.0 5.2 6.8 4.3 1.8 4.8 2.2 3.7 10.9 2.5 3.2 9.8 33.4 1.2 3.0 1.9 2.0 8.7 7.4 21.5 0.0 13.1 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 2.6 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.0 0.9 0.1 0.1 0.0 100.6 1.8 0.0 1.3 0.0 0.0 0.0 3.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.3 33.2 30.7 34.3 38.8 25.8 21.5 19.6 22.1 10.9 33.4 21.5 0.5 0.0 0.0 239.3 0.0 0.5 6.4 0.0 0.0 53.8 3.7 6.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 119.6 0.4 25.0 1.2 0.0 0.0 360.0 0.0 0.0 5.7 0.0 0.5 0.0 0.0 2.2 0.0 1.0 1.7 277.8 0.0 0.0 0.0 0.6 148.9 3.4 0.6 0.0 177.1 0.0 8.6 0.0 499.6 7.4 0.0 0.0 27.4 0.0 1.3 0.0 0.1 0.0 3.7 52.6 20.3 40.9 11.0 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.7 NUAK1 "ARK5, KIAA0537" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063345-106138954 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.7;Excitatory neurons: 150.5;Hepatic stellate cells: 136.3;Microglial cells: 93.7;Oligodendrocytes: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.0;EFO-21: 55.1;RH-30: 77.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: AB_2683349" "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavorable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 17.5 3.6 12.6 2.3 17.5 0.6 12.1 9.4 25.4 9.8 0.0 4.1 2.2 9.5 3.1 3.5 9.0 4.9 18.8 17.4 5.6 4.2 4.0 9.3 3.2 6.1 5.9 6.1 3.2 17.5 2.7 4.5 8.3 6.0 3.9 5.4 3.4 6.0 20.6 20.8 4.3 10.2 5.5 0.8 3.8 2.6 5.5 3.3 4.3 17.2 2.3 4.8 8.1 31.8 13.0 8.3 58.0 0.6 23.7 2.5 27.0 14.2 9.5 9.9 8.0 4.3 2.1 0.0 55.1 27.4 5.0 11.9 12.6 11.2 4.8 0.2 3.4 0.0 9.7 4.7 5.0 0.1 0.1 11.0 8.1 6.0 1.7 19.2 21.2 0.1 0.0 40.3 7.8 1.3 0.2 0.6 11.1 0.2 3.3 0.1 77.7 10.5 6.6 13.3 6.8 0.4 6.9 1.9 0.5 37.2 2.9 0.4 16.6 9.4 29.7 3.3 17.0 0.0 0.0 0.7 2.8 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.6 17.5 9.4 25.4 17.4 5.6 6.1 5.9 8.3 5.5 5.5 31.8 56.4 0.0 2.4 15.7 0.6 13.5 32.9 29.8 10.2 32.3 2.1 4.2 48.9 10.0 7.2 7.3 0.0 0.8 13.5 0.9 3.9 6.2 0.4 5.1 6.6 111.7 0.0 5.3 150.5 9.6 5.2 17.9 2.0 3.8 0.0 2.9 136.3 12.1 8.0 40.4 55.4 2.3 12.2 8.4 8.8 2.6 4.1 1.3 10.6 93.7 0.6 1.9 1.0 15.6 73.5 18.4 0.5 3.0 3.2 10.6 0.2 1.8 2.2 2.9 0.0 7.1 26.4 1.0 5.5 2.5 15.9 0.3 2.7 0.4 0.8 5.2 NUDCD2 "DKFZp686E10109, NudCL2" ENSG00000170584 "NudC domain containing 2" Q8WVJ2 5 163446526-163460102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037384, HPA037385" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 18000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Microtubules "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA037384: AB_2675447, HPA037385: AB_10673630" "unprognostic (3.96e-1)" "unprognostic (3.69e-2)" "prognostic favorable (2.80e-4)" "unprognostic (1.46e-1)" "unprognostic (9.12e-2)" "unprognostic (3.75e-3)" "unprognostic (1.84e-1)" "unprognostic (4.74e-1)" "unprognostic (3.47e-2)" "unprognostic (7.63e-3)" "unprognostic (1.81e-1)" "unprognostic (2.45e-1)" "unprognostic (3.91e-2)" "unprognostic (1.34e-2)" "unprognostic (6.86e-2)" "unprognostic (3.40e-2)" "unprognostic (7.85e-2)" 13.9 11.8 11.1 13.2 13.2 11.7 11.2 13.2 14.0 8.1 10.2 11.2 14.5 10.2 6.4 12.8 9.7 5.7 8.3 11.0 11.4 11.7 15.3 8.7 15.1 12.8 12.6 8.9 15.4 6.8 9.3 10.3 13.7 8.9 6.1 7.3 14.0 3.6 20.9 10.7 13.3 6.3 12.8 12.8 11.8 10.4 12.5 8.1 9.4 5.0 9.8 9.2 10.3 17.7 62.3 32.3 23.5 37.1 14.1 10.4 31.3 24.6 7.0 8.7 13.9 28.6 46.3 35.5 57.5 4.0 39.8 30.6 12.6 13.9 10.7 70.6 36.6 32.4 42.0 26.4 15.3 37.3 35.3 3.8 7.7 8.4 12.1 12.3 9.8 39.1 35.1 42.6 8.9 25.2 55.1 80.9 25.8 18.4 35.2 45.7 39.2 63.0 8.0 14.3 59.6 33.6 38.7 24.7 66.3 13.8 47.2 37.8 21.9 29.4 43.8 32.6 56.7 35.0 63.8 61.5 34.2 63.2 31.4 49.9 48.3 32.5 60.2 59.8 76.5 91.7 84.0 71.8 68.0 68.0 88.7 79.0 6.2 83.8 51.5 81.1 83.5 69.1 11.1 13.2 13.2 14.0 11.0 11.4 12.8 12.6 13.7 12.8 12.5 17.7 58.0 28.9 23.8 9.1 47.5 59.4 54.9 92.6 42.7 30.7 70.4 88.6 43.1 35.8 53.1 38.6 22.9 118.7 43.8 25.4 148.7 63.6 95.1 57.6 44.1 47.4 43.8 78.4 18.8 64.0 55.8 48.6 32.1 38.3 31.6 35.7 36.0 55.1 69.8 10.1 14.0 45.3 87.5 41.8 42.7 24.5 51.6 35.7 49.8 11.2 46.4 51.4 52.5 11.1 36.0 59.9 33.6 51.1 55.5 95.2 31.5 112.5 65.1 38.2 39.5 51.3 46.5 87.6 44.2 56.0 67.6 56.8 48.3 64.8 68.6 59.3 NUDCD3 "KIAA1068, NudCL" ENSG00000015676 "NudC domain containing 3" Q8IVD9 7 44379119-44490658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019136, HPA019528, HPA019529" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA019136: AB_1852370, HPA019528: AB_1852372, HPA019529: AB_1852374" "unprognostic (3.72e-2)" "unprognostic (9.28e-3)" "unprognostic (2.33e-2)" "unprognostic (2.05e-3)" "unprognostic (2.18e-3)" "unprognostic (2.05e-2)" "unprognostic (4.73e-2)" "unprognostic (2.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.96e-2)" "unprognostic (2.28e-1)" "unprognostic (5.62e-2)" "prognostic favorable (9.16e-4)" "unprognostic (3.51e-2)" "unprognostic (1.58e-2)" "unprognostic (1.45e-1)" "unprognostic (6.50e-2)" 2.9 2.8 6.8 1.3 9.0 2.8 2.8 3.2 7.2 2.5 0.0 2.4 1.2 2.2 2.4 2.7 3.5 2.2 7.5 6.6 5.1 2.2 1.8 2.4 2.2 4.4 5.5 3.1 3.3 3.7 1.8 1.7 5.6 2.8 1.8 4.8 2.4 3.3 8.2 3.1 2.0 3.0 3.9 1.9 2.7 3.9 5.6 2.1 2.7 5.7 2.2 2.3 1.8 6.3 2.6 4.9 3.4 6.3 4.2 3.4 1.3 4.1 4.0 4.8 4.9 3.3 1.8 8.1 3.0 5.5 6.6 3.0 4.8 5.6 2.8 4.8 4.9 2.2 2.9 2.3 3.8 3.9 1.3 3.1 3.7 3.6 4.1 2.8 5.9 2.4 6.1 2.6 3.6 2.3 1.6 3.7 4.3 2.5 6.3 2.3 3.7 3.0 2.7 4.0 3.6 10.6 2.4 4.5 1.8 3.4 3.4 5.7 5.7 3.3 3.4 2.2 3.3 7.3 8.1 4.0 3.6 4.5 5.9 0.6 0.8 0.9 1.0 0.8 1.1 1.0 0.9 0.9 0.7 1.0 0.9 0.9 0.5 0.8 1.0 0.6 1.0 0.9 6.8 9.0 3.2 7.2 6.6 5.1 4.4 5.5 5.6 3.9 5.6 6.3 30.5 12.8 19.2 35.9 26.4 11.3 13.0 16.5 20.5 40.9 29.3 25.3 44.5 17.2 16.0 38.6 54.2 19.6 21.9 22.7 23.5 29.6 87.7 27.4 34.4 25.3 17.4 22.3 59.6 21.6 18.1 23.9 23.9 30.9 9.5 35.8 22.5 32.8 18.3 48.8 58.8 25.1 26.4 17.9 9.5 98.3 30.4 13.9 16.0 46.9 21.2 24.8 34.0 36.2 61.2 27.4 18.8 28.2 14.3 15.9 27.2 26.8 21.9 40.2 32.9 17.8 25.2 106.6 21.1 25.5 16.2 14.4 26.2 18.9 27.8 13.3 NUDT19 RP2 ENSG00000213965 "Nudix hydrolase 19" A8MXV4 19 32691961-32713796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042761 Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "HPA042761: " "unprognostic (1.20e-1)" "unprognostic (2.90e-1)" "unprognostic (2.35e-3)" "unprognostic (6.61e-3)" "unprognostic (2.62e-2)" "unprognostic (2.44e-1)" "unprognostic (6.18e-3)" "unprognostic (1.97e-1)" "unprognostic (3.14e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (2.64e-2)" "unprognostic (2.81e-1)" "unprognostic (1.23e-1)" "prognostic favorable (1.35e-4)" 5.1 11.7 4.0 4.1 4.1 8.4 4.6 3.9 4.5 3.9 9.4 6.9 7.1 3.6 5.4 11.1 3.6 2.9 10.6 4.1 5.1 6.3 6.9 6.4 5.8 4.6 4.3 3.7 8.4 7.1 4.0 4.5 4.8 7.5 7.3 8.3 6.9 3.5 23.9 8.9 6.2 4.3 4.3 5.2 8.1 2.8 4.6 3.1 3.6 13.0 5.1 6.3 5.6 4.6 21.5 24.7 2.7 24.0 8.1 10.5 0.2 11.9 4.4 8.7 8.2 14.0 11.6 0.1 14.0 13.8 6.7 13.7 16.7 13.9 11.4 24.8 10.0 27.7 9.3 5.0 11.2 20.9 8.2 8.5 18.1 7.4 17.8 10.1 13.0 4.2 21.6 15.3 15.9 14.3 0.1 19.3 2.9 5.9 11.5 0.1 5.2 12.1 14.4 15.7 10.7 15.4 21.2 17.7 15.9 4.7 9.8 25.4 10.4 11.9 7.7 12.0 21.5 17.8 16.3 6.9 14.4 20.0 11.2 11.1 26.5 15.4 18.2 36.7 20.0 13.0 18.9 22.6 19.5 9.4 14.9 20.4 5.1 32.2 42.4 15.9 23.6 11.9 4.0 4.1 3.9 4.5 4.1 5.1 4.6 4.3 4.8 4.3 4.6 4.6 5.9 12.8 14.5 7.5 6.4 21.9 9.4 4.6 8.0 14.5 12.0 6.6 22.8 2.8 6.2 7.3 12.5 11.0 9.1 10.6 27.4 2.9 7.7 8.5 9.3 7.3 12.1 10.3 5.9 11.5 11.5 6.6 3.1 10.7 1.3 11.3 13.2 12.5 14.3 3.3 6.7 12.7 8.2 17.6 11.6 3.7 4.1 10.2 12.4 4.7 10.7 4.6 4.1 6.6 7.4 12.0 13.1 9.4 4.1 12.0 15.7 18.8 6.5 30.4 0.0 6.9 7.4 1.6 2.2 9.9 31.5 7.8 9.1 22.3 18.4 10.6 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165330-12196144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavorable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 35.1 32.4 23.0 30.6 26.4 24.1 26.7 27.5 30.5 24.6 29.5 32.0 27.5 14.3 23.7 40.7 24.6 18.4 14.9 23.4 26.0 36.3 88.8 26.0 39.3 27.3 24.9 18.0 25.9 33.1 35.5 31.1 27.4 21.0 36.0 27.4 25.1 14.0 6.2 33.2 25.4 17.6 25.0 34.2 22.6 13.1 25.4 53.5 27.8 7.6 47.4 28.9 27.8 31.8 136.4 98.0 114.6 107.1 107.5 105.6 100.8 96.9 61.5 111.9 119.1 142.5 125.9 134.2 82.4 79.2 70.0 133.1 162.0 150.6 102.1 110.8 160.8 111.9 114.3 209.3 112.0 77.1 75.2 111.7 88.4 122.3 61.7 86.3 144.9 209.4 153.5 88.9 103.2 123.8 143.5 87.0 100.4 215.0 60.1 128.0 42.4 157.2 106.0 46.1 56.6 82.3 117.4 90.8 142.2 132.0 155.9 77.9 91.6 47.0 90.6 134.3 121.9 74.3 141.6 179.3 99.7 97.3 36.0 29.6 60.8 115.2 69.9 65.7 80.4 72.7 73.9 82.6 87.6 64.6 50.4 68.4 163.8 57.4 52.2 149.2 123.4 71.6 23.0 26.4 27.5 30.5 23.4 26.0 27.3 24.9 27.4 25.0 25.4 31.8 42.1 25.6 55.1 23.2 43.8 43.0 57.8 121.2 28.5 21.1 28.6 30.7 4.5 32.9 72.3 23.9 16.7 82.6 49.8 35.0 74.3 82.2 35.3 61.1 44.4 42.6 38.3 43.5 34.6 82.9 150.6 40.3 33.1 31.9 31.7 41.4 41.7 131.8 128.7 21.9 38.2 41.2 79.3 41.8 32.2 11.7 39.4 39.7 30.2 12.2 85.0 37.4 62.8 34.2 41.2 73.8 35.2 29.0 66.1 33.7 52.6 130.6 103.9 25.5 32.9 21.2 40.1 20.2 33.6 52.4 60.5 58.1 49.7 54.4 57.4 46.9 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 160.7" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" NA NA 9900 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favorable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favorable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 23.6 36.1 20.8 16.2 21.4 6.7 19.7 25.5 38.5 27.6 39.1 27.0 42.6 24.8 32.2 19.6 24.9 16.2 28.8 21.9 24.7 40.4 46.6 23.0 13.7 21.0 20.5 26.7 67.6 55.3 29.1 19.9 21.9 30.4 27.1 20.1 28.1 23.8 42.1 16.6 40.3 23.8 19.6 14.7 22.3 22.5 22.1 13.4 28.8 45.0 14.8 22.4 24.3 26.0 30.8 25.6 34.0 19.8 67.6 39.6 26.0 59.8 35.6 21.3 21.1 17.1 53.1 47.6 58.9 47.6 41.0 21.1 32.1 38.1 33.2 34.5 24.0 13.4 34.5 31.8 42.4 25.6 21.2 41.5 52.4 25.6 22.6 45.5 41.6 13.7 40.3 30.0 38.7 33.4 39.1 23.2 29.1 68.5 12.0 45.0 31.8 27.0 160.7 24.2 41.3 28.7 37.6 63.0 30.8 44.5 36.8 38.2 43.7 34.7 34.3 25.8 27.8 21.5 18.7 37.9 51.3 21.9 48.2 1.6 17.9 5.9 19.1 21.2 18.2 22.2 18.5 19.5 21.4 18.8 22.5 26.0 1.8 15.6 24.0 20.6 19.0 16.0 20.8 21.4 25.5 38.5 21.9 24.7 21.0 20.5 21.9 19.6 22.1 26.0 32.6 67.3 44.8 20.2 14.9 9.9 40.4 45.0 9.6 15.3 11.3 13.1 40.9 30.0 55.0 23.9 27.1 33.2 13.1 21.0 41.1 44.7 28.6 26.0 26.2 25.8 16.8 6.7 21.7 36.5 32.5 29.4 8.6 27.0 20.8 23.3 18.2 47.5 33.2 6.7 24.0 18.0 40.7 12.7 11.0 11.5 25.4 14.7 10.6 20.6 16.4 26.8 8.2 18.6 24.8 29.4 37.0 26.7 15.8 32.9 55.7 56.2 41.0 18.6 26.3 36.9 23.7 44.5 23.6 15.7 9.5 37.6 12.1 29.8 24.9 27.3 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.8;Spermatocytes: 208.2;Spermatogonia: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 0.8 0.6 0.5 6.9 0.8 28.4 1.2 0.5 0.8 1.0 0.4 4.2 4.3 1.1 0.3 5.8 0.4 1.0 0.3 0.6 0.6 0.3 0.7 0.9 18.2 0.9 0.8 0.4 0.2 0.6 0.2 4.7 0.9 0.4 5.3 1.5 0.9 0.3 0.1 4.1 4.3 2.3 0.7 3.6 2.6 53.5 0.8 26.0 0.5 0.2 16.7 1.8 1.8 1.0 90.8 30.8 80.5 33.9 2.5 8.1 43.6 55.9 39.3 88.9 77.3 23.7 77.7 77.4 45.5 22.6 37.0 51.6 49.6 21.0 111.5 81.4 35.6 30.3 34.8 34.4 0.3 53.0 60.2 1.0 2.0 45.0 31.6 16.8 41.1 74.5 58.1 103.9 85.0 17.6 97.3 70.6 43.9 66.1 47.0 65.0 70.3 68.4 25.3 12.4 59.9 68.9 29.9 32.2 30.6 49.7 49.3 109.5 29.4 65.9 73.8 50.1 115.1 73.9 111.5 148.9 22.0 42.9 74.7 1.4 0.1 1.3 1.2 0.0 0.5 0.6 1.8 1.2 0.2 0.7 1.2 1.0 0.4 1.8 0.1 0.3 4.3 0.4 0.5 0.8 0.5 0.8 0.6 0.6 0.9 0.8 0.9 0.7 0.8 1.0 0.5 0.0 0.5 1.3 5.3 5.9 1.9 4.2 1.2 1.2 1.3 2.7 0.9 0.0 3.3 0.0 0.0 21.7 3.6 2.6 0.0 0.8 17.7 2.5 2.5 1.8 0.0 60.8 1.1 0.2 29.7 3.4 5.6 3.0 4.5 18.3 3.3 0.4 14.0 0.0 1.4 3.3 0.0 5.2 3.6 21.4 2.5 3.1 0.0 1.0 0.9 2.0 6.2 0.5 3.6 0.2 0.1 2.2 17.8 0.8 0.9 0.2 0.7 2.3 6.6 0.9 4.2 208.2 40.3 10.6 2.4 4.0 5.0 1.7 9.0 3.8 NUFIP2 "182-FIP, 82-FIP, FIP-82, KIAA1321, MGC117262, PIG1" ENSG00000108256 "Nuclear FMR1 interacting protein 2" Q7Z417 17 29255839-29294148 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 79.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067443 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Cytosol" "HPA067443: AB_2685841" "unprognostic (6.51e-2)" "unprognostic (6.96e-3)" "unprognostic (1.17e-1)" "unprognostic (2.95e-2)" "unprognostic (3.38e-1)" "unprognostic (2.12e-1)" "unprognostic (4.94e-3)" "unprognostic (1.40e-1)" "unprognostic (3.79e-2)" "unprognostic (9.42e-3)" "unprognostic (1.60e-3)" "unprognostic (5.24e-2)" "unprognostic (1.28e-3)" "unprognostic (3.45e-1)" "unprognostic (1.79e-1)" "unprognostic (7.18e-2)" "unprognostic (6.04e-3)" 15.3 14.9 4.4 22.7 3.6 79.9 12.5 10.3 20.4 12.7 11.7 14.9 16.2 11.5 11.9 17.2 10.9 14.0 13.6 5.1 19.9 13.0 24.0 21.0 19.8 12.1 14.7 12.0 14.7 18.4 11.0 29.6 11.0 12.1 13.0 23.1 15.5 9.8 15.9 12.1 13.2 10.3 2.1 20.7 18.7 14.2 10.8 18.0 13.5 17.6 17.5 16.4 14.2 14.1 42.5 67.1 38.9 27.2 32.8 38.0 65.1 41.3 24.8 31.1 28.4 75.0 22.5 68.5 60.1 28.5 27.7 58.6 31.4 28.9 39.3 74.0 55.9 51.8 64.7 19.8 30.3 66.6 53.8 33.1 34.5 34.4 36.7 35.9 23.2 24.8 86.2 49.5 32.1 34.8 70.6 30.1 40.2 32.2 24.9 57.2 66.8 29.4 26.1 68.4 37.1 23.5 73.6 136.6 44.6 51.5 47.3 44.2 38.5 59.1 59.1 35.0 71.3 68.4 68.9 79.3 39.0 34.9 51.6 13.6 6.1 8.5 5.6 5.9 4.3 8.5 5.5 6.2 5.2 7.6 7.0 5.9 25.4 5.1 9.6 12.1 3.2 2.3 4.4 3.6 10.3 20.4 5.1 19.9 12.1 14.7 11.0 2.1 10.8 14.1 139.7 80.1 67.0 58.1 76.8 99.5 78.2 40.0 118.4 55.3 105.0 124.8 81.7 38.6 69.3 31.3 95.9 69.2 124.3 72.6 15.6 33.9 35.2 108.2 139.0 85.9 48.3 55.6 47.4 27.9 31.3 86.4 82.6 154.2 46.2 41.2 55.0 54.6 44.6 57.2 47.1 62.5 20.3 74.7 108.8 24.9 35.4 122.9 40.9 41.2 50.0 35.2 37.0 44.7 85.9 37.4 43.1 35.0 65.2 91.8 26.5 27.6 88.8 60.6 19.7 171.7 78.5 36.6 29.8 120.8 97.7 182.0 93.8 51.8 57.1 111.9 NUP107 NUP84 ENSG00000111581 "Nucleoporin 107" P57740 12 68686951-68745809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031679 Uncertain "Nucleoplasm,Nuclear membrane,Centrosome" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane, Centrosome" "HPA031679: AB_2673992" "unprognostic (2.89e-1)" "unprognostic (3.32e-1)" "unprognostic (4.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.12e-9)" "unprognostic (4.03e-2)" "unprognostic (1.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.17e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (1.28e-6)" "unprognostic (3.43e-2)" "unprognostic (2.05e-1)" "unprognostic (1.00e-1)" "unprognostic (1.96e-1)" 15.4 11.1 5.0 17.9 6.3 24.0 17.8 8.2 6.0 12.9 6.3 13.0 10.3 16.7 14.3 10.7 13.5 9.3 11.4 4.6 5.0 10.6 11.8 12.8 25.8 5.6 5.7 16.3 9.3 11.8 6.8 13.8 5.5 12.0 16.2 14.7 10.3 12.2 11.7 15.8 12.9 14.0 5.4 15.8 11.0 20.9 5.5 25.6 10.3 12.1 25.5 12.4 10.7 7.6 53.1 66.8 77.8 56.7 22.6 28.6 84.1 56.6 32.4 83.0 68.9 67.6 43.7 96.3 53.7 27.2 36.9 59.4 88.4 41.7 109.8 90.8 65.6 110.1 46.2 57.4 14.2 97.9 35.6 15.2 19.4 66.5 43.2 29.0 50.3 54.9 133.7 67.3 52.8 64.3 81.3 85.2 85.8 20.3 64.6 81.9 93.6 57.8 36.1 55.3 45.7 46.9 62.7 46.5 34.4 60.4 69.8 46.7 31.1 45.0 45.8 53.0 69.9 29.2 62.2 115.2 34.7 70.2 54.2 10.5 9.2 14.4 17.7 12.5 23.4 18.7 17.5 19.3 10.2 18.7 21.5 19.5 2.4 30.5 23.2 8.1 20.0 11.8 5.0 6.3 8.2 6.0 4.6 5.0 5.6 5.7 5.5 5.4 5.5 7.6 18.3 12.8 17.7 13.7 38.1 17.3 18.4 28.1 25.0 23.8 12.5 11.4 13.5 12.8 18.9 9.2 18.8 30.7 30.3 12.2 11.7 22.8 45.3 12.6 18.2 20.6 8.5 64.4 23.8 17.6 30.8 19.6 16.3 10.2 15.8 35.6 15.4 7.0 17.5 13.5 20.1 12.6 42.7 13.9 16.2 9.6 38.8 18.3 19.6 15.9 27.0 16.7 36.0 21.6 34.3 22.1 9.9 21.8 22.9 19.4 10.5 6.4 21.9 29.6 13.1 18.4 18.2 89.4 51.9 18.7 17.6 14.1 27.0 24.5 16.8 12.5 NUP188 KIAA0169 ENSG00000095319 "Nucleoporin 188" Q5SRE5 9 128947699-129007096 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Spermatocytes: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061750, HPA063942" Approved Uncertain Nucleoplasm,Nucleoli,Cytosol No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli, Cytosol" "HPA061750: AB_2684602, HPA063942: AB_2685156" "unprognostic (4.64e-1)" "unprognostic (6.91e-3)" "unprognostic (2.36e-1)" "prognostic favorable (5.20e-5)" "unprognostic (9.50e-2)" "unprognostic (4.41e-2)" "unprognostic (1.85e-3)" "unprognostic (1.91e-1)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (7.78e-2)" "unprognostic (4.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.68e-2)" "unprognostic (2.87e-1)" "unprognostic (2.81e-3)" "unprognostic (3.53e-3)" 13.1 15.5 9.5 16.2 10.9 21.4 11.9 13.1 10.0 15.6 10.0 14.8 7.5 13.1 8.0 23.7 11.9 9.4 13.6 9.0 9.7 10.4 9.9 16.7 18.0 11.4 11.1 11.4 12.0 13.1 14.9 11.8 11.8 13.5 11.5 13.7 13.9 9.8 15.7 21.4 13.4 13.9 9.3 16.8 13.6 56.6 10.9 27.3 12.6 10.3 20.4 16.1 15.6 11.7 33.6 62.6 50.8 69.7 37.7 37.2 45.4 45.9 35.9 82.1 54.4 76.3 26.2 58.2 16.7 50.7 52.9 96.6 115.2 56.8 61.0 47.1 55.5 51.9 113.3 60.8 23.9 89.6 50.2 26.0 26.3 86.5 43.8 24.1 47.8 74.1 116.0 40.3 58.8 84.6 77.3 36.5 68.2 63.8 59.4 69.9 109.8 59.2 25.5 37.3 71.2 34.3 118.8 44.7 17.1 37.2 49.3 32.7 39.0 67.7 48.2 69.2 83.5 34.1 67.9 76.9 39.5 56.3 51.2 8.2 4.8 1.7 7.5 8.9 9.7 4.9 6.4 7.4 6.8 4.3 6.4 7.0 0.6 5.4 5.2 2.9 8.3 6.8 9.5 10.9 13.1 10.0 9.0 9.7 11.4 11.1 11.8 9.3 10.9 11.7 9.6 0.0 12.6 15.7 10.4 6.5 6.6 6.4 5.7 16.2 7.6 7.6 3.5 10.0 5.9 5.5 45.9 8.0 8.6 6.0 1.9 6.1 14.5 7.9 13.2 9.4 9.1 8.6 11.3 6.5 6.5 9.5 9.7 12.2 6.3 24.0 11.0 5.0 8.4 20.2 13.1 7.2 6.1 4.7 6.1 5.7 9.6 8.1 1.8 12.2 5.3 6.8 9.2 12.5 13.0 9.0 2.3 11.7 8.3 10.1 3.3 2.5 6.3 24.4 26.3 18.2 7.1 52.9 37.8 13.6 11.2 8.6 9.4 12.5 7.4 8.2 NUP35 MP44 ENSG00000163002 "Nucleoporin 35" Q8NFH5 2 183117513-183161680 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 151.6;Late spermatids: 424.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018401, HPA018410, HPA018441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "Plasma membrane" "HPA018401: AB_1854719, HPA018410: AB_1854721, HPA018441: AB_1854720" "unprognostic (6.18e-3)" "unprognostic (3.15e-1)" "unprognostic (1.83e-1)" "unprognostic (3.58e-3)" "unprognostic (1.37e-1)" "unprognostic (9.91e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.95e-1)" "unprognostic (6.21e-3)" "prognostic favorable (3.45e-4)" "unprognostic (2.32e-2)" "unprognostic (1.61e-3)" "unprognostic (1.78e-3)" "unprognostic (6.78e-2)" "unprognostic (3.47e-2)" "unprognostic (1.24e-1)" "unprognostic (3.96e-2)" 7.7 8.9 5.9 6.9 7.3 4.6 13.1 8.9 7.8 8.5 5.0 7.6 6.3 8.1 7.7 8.7 8.9 6.9 6.2 6.1 5.9 10.2 14.4 5.9 9.1 5.5 5.9 10.4 10.2 8.9 6.3 7.8 5.5 7.8 9.1 9.0 8.4 7.0 7.4 9.0 6.5 8.9 6.6 5.7 7.2 24.2 5.5 10.4 8.2 8.7 11.0 9.2 8.0 6.4 19.7 19.7 32.5 20.5 11.8 11.5 23.2 23.0 18.8 35.3 33.5 37.6 24.7 34.6 22.0 12.4 40.9 17.4 45.4 26.7 57.8 29.6 27.8 32.6 16.4 43.9 8.2 23.6 21.8 8.2 13.8 29.9 28.9 7.9 20.8 20.5 28.7 25.3 27.8 23.7 28.7 29.1 57.9 31.6 61.9 34.3 25.2 25.0 34.0 24.7 29.4 20.3 21.6 26.6 26.0 24.4 17.0 16.2 10.6 28.6 19.7 23.3 26.5 16.4 38.3 37.9 19.3 16.8 39.2 0.0 4.1 1.4 4.9 5.5 8.6 7.2 6.3 6.0 3.2 6.5 7.5 6.7 0.2 5.6 6.6 3.1 6.7 4.1 5.9 7.3 8.9 7.8 6.1 5.9 5.5 5.9 5.5 6.6 5.5 6.4 9.6 9.6 6.8 6.5 10.3 26.0 20.7 17.5 12.5 10.8 9.3 8.9 4.7 14.3 13.8 16.5 18.8 23.6 8.5 3.3 11.7 15.5 151.6 5.3 8.1 10.2 3.6 12.6 11.5 12.7 20.2 10.8 5.1 6.4 8.2 8.1 12.8 12.6 8.4 6.7 12.0 7.5 16.2 4.4 9.9 424.7 9.6 3.6 21.4 2.8 5.0 11.4 7.2 17.1 12.8 11.1 5.1 8.2 7.5 12.8 4.2 14.5 6.9 19.1 13.1 18.7 11.6 39.8 21.1 11.3 27.4 9.4 11.5 9.0 9.6 11.2 NUP43 "bA350J20.1, FLJ13287" ENSG00000120253 "Nucleoporin 43" Q8NFH3 6 149724315-149749665 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027126, HPA027291, HPA028500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "HPA027126: AB_10599301, HPA027291: AB_10601851, HPA028500: AB_10602287" "prognostic unfavorable (2.08e-4)" "unprognostic (3.02e-1)" "unprognostic (3.86e-2)" "unprognostic (1.45e-3)" "unprognostic (2.29e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (7.13e-7)" "unprognostic (5.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-2)" "unprognostic (6.25e-3)" "unprognostic (2.02e-1)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" 8.4 8.6 6.2 11.4 7.5 6.2 13.6 7.2 6.9 9.7 6.5 9.4 8.7 9.8 7.5 9.5 8.2 6.4 10.8 5.6 6.6 9.9 9.6 8.0 15.9 6.6 6.6 9.1 12.2 8.9 5.6 11.4 6.9 10.3 9.7 9.8 8.8 9.2 14.2 13.5 10.9 9.4 6.6 13.6 9.8 7.9 6.5 12.8 11.1 11.6 17.0 9.0 9.1 8.3 21.1 34.9 31.1 49.6 20.0 23.7 48.9 36.3 20.3 34.0 43.0 49.5 19.5 61.4 36.6 20.2 32.1 33.5 54.6 31.6 58.3 27.8 38.2 70.9 35.5 49.6 13.4 73.2 44.1 15.3 16.4 49.9 33.1 13.0 27.5 34.6 71.4 33.6 29.6 20.7 52.2 30.4 28.3 24.1 21.0 50.2 43.2 20.6 23.2 28.9 12.9 21.2 43.4 27.1 14.2 25.6 28.7 30.9 21.3 28.3 30.2 41.2 53.9 20.5 43.3 63.9 25.2 49.3 40.5 2.9 4.9 3.4 3.5 5.4 3.8 4.3 4.2 3.5 2.6 6.2 4.3 5.5 1.9 3.7 4.8 5.0 4.9 2.2 6.2 7.5 7.2 6.9 5.6 6.6 6.6 6.6 6.9 6.6 6.5 8.3 5.8 3.2 7.8 9.1 11.5 7.9 5.5 4.7 2.8 11.9 4.5 5.0 14.3 11.5 5.2 3.7 6.2 10.9 11.3 4.7 3.9 9.0 33.3 4.3 8.7 5.7 10.2 7.6 4.8 7.8 12.2 6.4 6.1 6.0 0.0 12.8 8.2 4.4 7.8 6.7 5.1 6.9 2.0 11.9 6.9 78.9 10.2 6.5 8.8 9.4 15.1 10.5 9.2 11.1 17.4 6.6 2.3 10.5 8.7 6.2 3.9 5.4 4.2 9.5 13.1 6.9 22.1 7.1 9.2 5.5 8.5 6.6 7.6 7.4 8.4 6.7 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NYNRIN "CGIN1, FLJ11811, KIAA1305" ENSG00000205978 "NYN domain and retroviral integrase containing" Q9P2P1 14 24399003-24419283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 18.2;Squamous epithelial cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.4;HEL: 14.7;HUVEC TERT2: 35.6;RT4: 29.8;TIME: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018945 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA018945: AB_1859538" "unprognostic (9.41e-3)" "unprognostic (3.96e-2)" "unprognostic (2.02e-1)" "unprognostic (4.49e-3)" "unprognostic (5.08e-2)" "unprognostic (1.14e-2)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.44e-3)" "unprognostic (4.21e-1)" "unprognostic (1.01e-1)" "unprognostic (4.51e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (3.39e-1)" "unprognostic (2.43e-1)" 8.7 3.7 4.3 3.1 3.9 0.4 6.3 16.3 4.6 16.8 5.4 7.6 4.0 11.5 28.0 11.6 16.9 8.6 7.5 3.2 6.6 6.3 4.5 8.1 1.9 5.8 5.4 35.1 3.8 5.8 5.8 12.8 6.3 7.5 5.5 1.8 7.4 14.9 3.8 13.3 5.3 10.5 3.2 4.4 6.0 5.1 7.8 4.5 7.8 4.2 2.9 9.5 14.0 2.8 0.2 0.1 4.6 0.0 6.3 13.0 0.3 2.2 2.3 1.5 1.6 3.3 14.4 0.4 0.6 8.6 0.2 0.0 7.5 0.2 1.5 0.0 0.8 14.7 2.0 0.3 4.7 0.0 0.0 13.3 0.6 1.0 0.0 2.6 35.6 0.1 2.4 0.0 0.2 0.6 0.0 0.8 2.7 1.0 0.0 1.9 0.0 0.0 0.0 29.8 0.6 10.0 0.0 1.3 0.2 11.2 2.5 2.1 17.4 0.1 8.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.3 3.9 16.3 4.6 3.2 6.6 5.8 5.4 6.3 3.2 7.8 2.8 15.2 3.2 1.7 4.9 0.1 4.6 3.9 9.5 15.4 0.5 1.8 3.6 3.1 8.6 15.6 9.2 0.0 1.1 1.6 2.7 0.0 4.1 0.8 1.4 10.8 15.0 5.4 3.6 1.0 3.0 1.0 10.1 10.7 1.7 0.0 12.0 18.2 2.7 10.7 0.0 3.9 9.0 4.1 9.0 1.4 0.2 2.5 1.4 3.6 3.7 0.7 5.4 0.0 0.5 0.1 4.8 5.1 0.4 1.2 1.2 1.0 0.3 10.8 0.2 0.0 1.2 7.3 0.3 1.2 18.0 3.8 1.1 0.3 1.5 8.8 4.5 OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938051-112976460 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 15.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 202.5;BJ hTERT+ SV40 Large T+ RasG12V: 224.5;GAMG: 89.8;RT4: 62.6" "Not detected" "Not detected" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" Yes No 21000 "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: AB_10794990, HPA041372: AB_10795590" "unprognostic (8.47e-2)" "unprognostic (9.13e-2)" "unprognostic (1.27e-2)" "unprognostic (4.39e-3)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.14e-3)" "unprognostic (8.06e-3)" "unprognostic (3.19e-1)" "unprognostic (1.73e-2)" "unprognostic (2.29e-3)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.23e-5)" "unprognostic (4.25e-2)" "unprognostic (1.37e-2)" "unprognostic (3.29e-2)" "unprognostic (2.93e-2)" 8.1 4.1 3.2 11.5 3.1 20.9 6.0 2.3 2.5 11.0 1.1 7.1 7.1 3.9 1.5 15.8 5.2 11.3 7.0 2.2 2.4 5.6 4.4 12.6 6.0 8.7 3.6 3.8 3.8 3.2 3.5 11.1 6.4 3.4 6.2 0.6 27.7 2.7 3.0 5.4 6.5 9.3 11.8 17.9 11.0 2.3 4.1 16.1 4.1 5.9 6.4 14.4 7.8 3.0 23.2 34.4 0.3 5.5 1.0 4.6 2.1 2.6 25.3 202.5 224.5 24.1 20.5 0.7 7.3 8.1 89.8 15.7 3.3 22.7 11.2 9.7 1.2 15.9 16.3 4.0 3.9 4.5 6.6 0.9 7.2 32.8 1.3 4.0 11.7 3.9 0.5 3.1 2.0 13.3 8.0 2.7 1.4 33.7 22.8 13.5 11.6 0.1 7.0 62.6 0.6 0.1 19.8 5.5 14.8 0.2 25.7 1.1 9.5 4.6 4.0 5.5 6.5 0.8 21.0 0.2 4.9 12.9 16.7 1.0 7.8 0.8 1.4 7.4 1.7 2.3 2.0 2.3 4.1 1.0 1.8 1.7 9.7 2.7 15.3 0.3 2.6 3.5 3.2 3.1 2.3 2.5 2.2 2.4 8.7 3.6 6.4 11.8 4.1 3.0 19.9 3.2 3.9 0.7 3.8 3.4 5.6 13.5 5.2 0.4 3.1 2.7 1.7 0.0 5.1 3.7 0.0 5.4 1.8 14.7 3.9 11.2 5.9 1.8 4.1 20.8 1.8 0.8 0.3 9.8 20.9 5.5 16.3 5.6 1.3 21.9 9.3 1.7 18.7 0.0 0.4 6.8 8.2 5.8 7.0 10.8 10.2 16.7 1.8 5.6 30.2 3.0 8.2 3.5 0.0 21.2 8.2 15.1 1.4 11.8 4.5 2.0 2.3 0.5 0.0 2.5 5.0 0.8 0.7 14.4 4.7 1.9 6.5 9.2 5.4 26.8 OBI1 "C13orf7, FLJ13449, RNF219" ENSG00000152193 "ORC ubiquitin ligase 1" Q5W0B1 13 78614289-78659155 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 14.5;Cardiomyocytes: 19.5;Cytotrophoblasts: 15.8;dendritic cells: 8.0;Extravillous trophoblasts: 12.2;Hofbauer cells: 9.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034785, HPA034786" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034785: AB_10601496, HPA034786: AB_2674331" "unprognostic (2.99e-1)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.60e-1)" "unprognostic (7.88e-2)" "unprognostic (1.34e-2)" "unprognostic (2.83e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-1)" "unprognostic (3.84e-2)" "unprognostic (4.26e-3)" "prognostic unfavorable (4.99e-6)" "unprognostic (6.87e-2)" "unprognostic (2.01e-1)" "unprognostic (6.91e-2)" "unprognostic (2.53e-2)" 5.8 4.8 5.4 6.1 5.8 2.4 6.7 6.6 6.7 5.9 3.0 4.8 4.8 7.1 4.5 5.0 5.6 4.5 7.1 5.6 6.1 4.6 4.4 5.2 9.9 5.5 5.9 7.6 4.1 4.1 2.9 7.4 5.0 5.5 5.3 9.6 4.2 6.1 4.8 5.5 4.7 6.5 6.1 7.3 4.5 14.8 7.2 13.3 5.9 6.4 11.3 6.0 4.5 5.9 23.7 9.1 39.1 23.1 13.5 12.9 17.8 19.3 14.5 18.7 23.3 18.3 17.3 39.8 9.2 12.4 12.2 23.0 31.2 15.3 32.6 24.9 22.8 61.0 11.4 16.1 11.3 59.6 18.2 12.4 16.7 15.7 16.8 10.6 15.6 19.9 16.1 5.3 24.6 6.6 36.5 20.2 0.0 25.1 10.0 42.0 32.2 15.4 12.7 12.5 28.4 15.9 13.4 16.9 14.8 22.2 8.6 47.3 12.9 16.2 14.7 10.7 16.3 5.5 6.6 37.9 25.9 35.6 17.8 4.9 5.4 7.5 7.9 8.8 9.5 8.8 8.8 9.8 6.3 8.9 10.8 9.8 1.8 11.1 10.3 5.3 9.6 6.6 5.4 5.8 6.6 6.7 5.6 6.1 5.5 5.9 5.0 6.1 7.2 5.9 14.5 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 15.8 8.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 12.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 5.1 1.1 0.0 0.0 0.0 OCRL "Dent-2, OCRL1" ENSG00000122126 "OCRL inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" Hydrolase "Cataract, Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 1.2;monocytes: 3.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012495 Approved Approved "Microtubules,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Microtubules, Centriolar satellite" "HPA012495: AB_1851804" "prognostic unfavorable (2.93e-5)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (6.34e-3)" "unprognostic (9.88e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-2)" "unprognostic (2.68e-1)" "unprognostic (3.08e-3)" "unprognostic (2.56e-2)" "unprognostic (6.30e-3)" "unprognostic (1.74e-1)" "unprognostic (4.61e-3)" "unprognostic (4.10e-1)" "unprognostic (5.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" 13.9 23.8 12.4 4.7 13.2 5.0 12.7 5.3 13.6 14.9 27.2 16.4 8.0 19.4 16.1 11.6 16.7 8.3 10.7 13.1 20.3 9.5 15.7 10.0 2.8 9.6 14.0 28.4 13.0 34.6 25.6 11.2 17.4 18.5 12.4 9.9 11.0 21.3 14.8 12.4 12.2 15.0 7.6 7.9 14.5 24.6 18.6 4.4 16.8 6.7 3.0 22.8 12.3 8.6 19.3 20.5 17.0 18.7 29.3 24.1 17.1 28.5 22.3 28.2 26.3 14.2 13.3 1.5 46.7 24.1 33.0 11.6 30.5 20.9 29.2 0.1 21.5 5.8 18.5 14.1 21.1 5.7 0.6 20.7 27.3 28.3 27.3 27.7 21.2 8.4 7.9 13.6 28.7 24.2 4.3 8.2 6.2 24.4 30.9 4.2 17.6 11.5 16.1 19.1 20.5 26.1 13.5 18.0 14.6 21.5 13.2 10.0 19.3 23.0 10.6 24.6 29.1 3.8 3.3 3.7 16.2 21.4 18.8 0.0 1.0 0.0 0.1 1.1 0.3 0.1 0.0 0.0 1.2 0.1 0.2 0.1 0.1 0.0 3.6 0.4 0.0 0.4 12.4 13.2 5.3 13.6 13.1 20.3 9.6 14.0 17.4 7.6 18.6 8.6 6.7 3.2 7.8 14.4 2.6 4.7 3.4 5.4 3.4 9.9 9.3 5.6 10.3 4.3 8.8 18.4 6.2 6.4 0.3 14.4 3.9 5.3 31.2 4.9 6.9 6.4 17.5 3.8 20.0 3.6 5.4 7.8 11.7 6.1 0.0 17.0 8.2 11.5 5.0 13.5 23.1 11.8 6.1 11.8 4.0 8.9 23.0 5.8 8.8 21.5 4.3 9.6 0.0 17.6 21.0 8.5 8.3 34.3 1.4 5.9 15.7 5.2 5.4 7.2 0.0 4.5 6.0 6.8 14.6 8.3 7.4 5.7 1.0 7.6 12.2 8.4 ODF3L2 "C19orf19, FLJ40059" ENSG00000181781 "Outer dense fiber of sperm tails 3 like 2" Q3SX64 19 463346-474983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 8.2;testis: 23.4" "Cell type enriched" "Detected in some" 5 "Late spermatids: 1184.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA067065, HPA067973" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli "Nucleoplasm, Golgi apparatus" "HPA067065: , HPA067973: AB_2685937" "unprognostic (3.75e-4)" "unprognostic (1.79e-2)" "unprognostic (1.83e-3)" "unprognostic (9.69e-3)" "unprognostic (5.88e-2)" "unprognostic (5.65e-2)" "unprognostic (9.32e-2)" "unprognostic (1.35e-1)" "unprognostic (2.34e-2)" "unprognostic (1.77e-2)" "unprognostic (2.13e-2)" "unprognostic (4.06e-2)" "unprognostic (2.02e-5)" "unprognostic (3.13e-3)" "unprognostic (8.99e-2)" "unprognostic (3.05e-1)" "unprognostic (1.99e-1)" 0.3 0.3 0.7 0.0 0.7 0.0 0.3 0.4 0.9 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.5 0.5 0.2 0.3 0.2 0.0 0.7 0.6 0.1 0.1 0.0 0.1 0.2 0.7 0.2 0.0 0.1 0.0 0.0 8.2 0.1 0.2 0.0 0.5 0.7 0.1 23.4 0.8 0.0 0.3 0.1 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.4 0.9 0.5 0.5 0.7 0.6 0.7 0.5 0.8 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.8 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 5.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1184.9 8.4 0.6 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 7.6 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OLFM1 "AMY, NOE1, NOELIN, OlfA" ENSG00000130558 "Olfactomedin 1" Q99784 9 135075422-135121180 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 555.7;choroid plexus: 246.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.1;Hepatic stellate cells: 78.1;Inhibitory neurons: 70.0" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.8;myeloid DC: 2.6" "Group enriched" "Detected in many" 27 "dendritic cells: 2.6;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HeLa: 96.0;MCF7: 84.1;NTERA-2: 104.9;OE19: 78.9;SCLC-21H: 155.6;SiHa: 131.8;T-47d: 200.2;U-2197: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057444 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in brain" NA NA 200000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Cytosol" "HPA057444: AB_2683443" "unprognostic (6.77e-2)" "prognostic favorable (7.14e-4)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.69e-3)" "unprognostic (2.67e-1)" "unprognostic (6.04e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (9.46e-3)" "unprognostic (4.60e-2)" "unprognostic (1.51e-1)" "unprognostic (6.20e-2)" "unprognostic (7.53e-4)" 36.7 25.4 410.4 13.0 427.0 0.2 36.8 309.6 555.7 29.9 246.9 24.0 5.0 29.0 70.4 12.1 30.3 8.6 20.7 474.7 309.0 20.3 4.8 15.0 14.5 296.6 301.7 19.4 12.3 4.9 82.8 1.0 293.9 19.3 13.8 47.3 14.0 18.1 17.5 15.3 16.5 17.9 279.9 35.1 15.4 6.8 317.0 11.5 17.5 23.0 19.1 25.0 26.7 372.3 0.0 6.1 12.1 0.2 1.7 1.4 0.5 3.6 0.0 0.0 0.0 0.1 2.7 0.1 0.8 5.2 49.2 2.3 2.6 0.0 0.0 14.4 0.9 0.2 96.0 0.0 0.5 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.3 84.1 0.5 0.3 104.9 78.9 0.0 0.1 0.3 48.3 0.0 0.1 155.6 20.5 131.8 0.4 8.6 7.9 200.2 0.0 0.1 7.7 16.6 87.1 0.2 0.2 0.1 0.3 0.7 0.1 4.3 0.0 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 410.4 427.0 309.6 555.7 474.7 309.0 296.6 301.7 293.9 279.9 317.0 372.3 44.2 0.0 7.9 43.8 0.1 9.7 3.3 0.0 3.4 21.6 3.1 3.0 5.9 11.5 1.8 0.0 43.8 0.0 0.1 2.4 0.0 9.7 5.8 0.5 20.4 50.0 2.4 0.0 193.1 2.7 0.0 17.3 0.0 0.7 2.5 14.4 78.1 1.1 0.4 38.7 70.0 2.5 0.0 3.2 7.3 11.9 44.4 2.8 21.4 32.8 2.7 38.6 0.0 48.7 17.3 2.5 2.5 29.3 0.4 5.1 0.0 0.1 0.0 15.7 0.0 13.3 8.8 0.6 3.7 1.3 6.3 0.0 0.7 12.9 4.2 1.4 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.0;Hofbauer cells: 202.1;Macrophages: 202.6;Syncytiotrophoblasts: 463.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 125.4;HaCaT: 64.9;HHSteC: 125.1;hTCEpi: 58.4;SiHa: 248.8;SK-BR-3: 96.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" 3.0 3.3 9.0 29.1 13.1 23.8 3.6 18.9 16.9 3.3 8.8 0.7 1.3 1.6 1.3 0.5 2.1 7.4 1.5 9.4 13.3 8.2 3.1 100.2 0.7 25.5 15.6 0.3 2.2 4.1 2.7 114.5 26.0 2.3 1.0 5.1 3.8 1.0 0.5 0.6 1.2 2.1 27.6 0.8 2.3 4.7 24.0 2.8 2.5 0.0 0.8 6.0 0.3 52.6 7.3 0.5 0.1 0.3 0.3 0.0 16.8 12.1 2.2 7.3 2.6 125.4 0.1 1.6 0.0 15.8 0.5 64.9 0.0 0.7 4.9 0.0 0.0 0.0 6.1 0.0 125.1 0.1 0.3 1.0 58.4 0.3 0.0 0.0 0.3 0.1 0.1 0.7 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.2 13.3 0.4 0.2 248.8 96.9 0.0 17.4 27.1 0.0 0.1 0.2 1.4 0.0 0.0 0.4 0.3 0.4 0.1 0.1 0.1 0.6 0.6 1.3 0.1 0.1 0.1 0.1 0.1 0.0 2.8 0.2 0.1 0.1 1.4 0.1 0.1 0.3 0.1 0.6 9.0 13.1 18.9 16.9 9.4 13.3 25.5 15.6 26.0 27.6 24.0 52.6 1.9 28.9 27.4 0.0 4.0 1.5 0.4 0.5 0.0 0.4 1.1 4.6 0.1 1.5 4.4 0.0 0.0 399.0 0.3 0.0 0.0 0.1 13.4 0.1 0.0 10.8 0.0 0.4 2.3 0.0 14.6 10.9 0.5 0.1 15.2 0.0 0.0 0.5 202.1 0.0 0.2 0.0 0.0 18.9 79.5 11.6 0.3 202.6 0.0 40.3 21.3 0.1 0.0 0.5 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.2 6.6 0.2 0.0 0.2 0.4 0.1 0.2 0.8 0.6 463.1 1.6 0.1 0.0 0.3 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 14.5" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 4.5;Excitatory neurons: 6.7;Extravillous trophoblasts: 8.0;Glandular and luminal cells: 9.8;Inhibitory neurons: 10.1;Leydig cells: 4.7" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.1 0.1 7.3 0.0 14.5 0.0 0.0 1.3 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 5.4 0.0 0.0 0.1 0.0 5.8 1.7 0.0 0.0 0.0 0.0 0.2 5.1 1.6 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 6.9 0.1 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 14.5 1.3 8.3 3.9 5.4 5.8 1.7 5.1 0.3 6.9 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 4.5 0.6 0.1 0.0 0.0 6.7 0.0 8.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.0 0.0 0.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 OSBP OSBP1 ENSG00000110048 "Oxysterol binding protein" P22059 11 59574398-59615774 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039227, HPA043625" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 70000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039227: AB_2676401, HPA043625: AB_2678587" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "prognostic favorable (2.08e-5)" "unprognostic (7.80e-3)" "unprognostic (7.32e-2)" "unprognostic (2.79e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (7.42e-2)" "unprognostic (1.42e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.08e-7)" "unprognostic (1.25e-1)" "unprognostic (9.00e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" 19.6 41.7 14.1 15.5 15.2 27.2 27.4 15.3 18.9 24.7 18.4 26.8 29.4 20.0 31.6 19.6 22.4 19.5 25.5 15.0 15.6 42.8 57.6 18.5 17.8 15.4 16.7 22.4 37.3 44.9 16.1 22.9 16.7 25.9 28.3 15.9 30.1 27.0 57.7 26.6 25.5 21.2 14.0 15.6 27.8 18.0 15.7 24.0 32.3 43.8 23.7 19.6 17.1 15.1 40.9 33.6 24.7 33.2 56.5 52.4 26.8 32.9 42.3 38.4 34.4 38.1 40.2 41.1 42.7 37.9 47.2 41.4 45.4 43.5 43.0 40.0 20.9 28.1 25.1 25.8 60.2 36.2 52.9 40.4 52.8 36.2 94.4 40.0 41.7 38.3 48.6 37.3 34.5 19.0 34.0 26.2 28.0 59.5 32.7 32.5 39.8 28.6 45.6 47.0 28.5 20.3 38.6 47.7 46.0 33.6 66.9 22.7 45.8 32.7 22.8 49.5 22.3 51.9 45.2 41.4 37.0 25.6 26.8 1.7 1.6 1.5 2.8 1.4 2.6 2.2 2.9 2.3 1.6 1.6 2.6 2.1 1.5 2.2 1.3 4.0 1.3 1.1 14.1 15.2 15.3 18.9 15.0 15.6 15.4 16.7 16.7 14.0 15.7 15.1 29.2 25.6 9.0 14.7 18.9 39.6 16.4 13.7 29.6 23.8 38.0 27.1 34.1 32.9 19.0 27.6 22.9 14.2 31.1 34.0 7.9 14.0 8.8 37.9 52.7 21.8 30.0 10.5 25.6 18.6 14.7 21.1 22.4 43.8 27.9 21.8 15.4 67.1 16.0 26.9 22.9 40.0 8.2 12.9 16.9 14.5 15.8 17.9 14.2 12.2 9.6 15.7 18.6 18.1 23.3 20.2 20.5 19.9 32.2 31.2 34.6 21.0 27.8 21.7 6.6 28.4 19.3 25.1 14.5 27.0 47.3 30.8 20.0 43.5 28.4 26.4 OSBPL10 ENSG00000144645 "Oxysterol binding protein like 10" Q9BXB5 3 31657912-32077580 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 440.2;Late spermatids: 1206.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 17 "memory B-cell: 11.5;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 22 "B-cells: 11.5" "Cell line enhanced" "Detected in many" "hTERT-HME1: 93.3;RPTEC TERT1: 118.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003636 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane, Cytosol" "HPA003636: AB_1079529" "unprognostic (5.28e-3)" "unprognostic (2.06e-2)" "unprognostic (4.21e-2)" "unprognostic (1.44e-2)" "unprognostic (1.98e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-2)" "unprognostic (3.63e-2)" "unprognostic (8.55e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.15e-1)" "prognostic favorable (1.51e-4)" "unprognostic (5.86e-2)" "unprognostic (7.64e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.85e-4)" 8.3 2.6 3.1 7.8 3.0 1.2 6.0 0.1 3.6 10.2 6.5 6.5 3.7 8.4 6.6 13.0 5.9 11.4 2.9 4.8 2.7 13.3 2.2 5.8 12.9 1.2 4.9 3.1 1.6 1.6 6.7 22.3 3.0 11.8 7.8 5.5 6.8 20.9 1.6 4.9 6.7 11.1 0.3 9.5 6.1 25.0 1.3 2.8 3.5 2.2 17.8 20.3 5.9 2.6 19.3 10.6 2.0 39.3 4.2 7.4 63.1 5.2 6.1 4.9 6.8 27.0 14.3 45.6 48.8 1.1 17.0 11.5 8.9 45.1 6.0 0.3 8.2 0.1 26.4 18.3 2.7 0.1 0.2 7.7 39.7 7.8 93.3 18.2 23.4 0.2 0.1 0.2 22.7 16.0 0.2 0.1 24.9 64.9 26.5 0.5 0.8 0.9 118.3 7.8 3.0 0.5 8.9 17.0 5.4 36.9 11.1 0.2 15.2 6.1 61.7 0.5 26.2 4.1 3.0 42.6 8.6 0.1 39.3 0.2 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 6.7 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3.1 3.0 0.1 3.6 4.8 2.7 1.2 4.9 3.0 0.3 1.3 2.6 20.5 9.6 3.9 2.9 50.6 10.8 7.5 10.1 4.6 7.3 13.8 6.6 2.3 4.3 7.3 7.3 0.0 15.3 2.4 7.9 9.8 1.8 440.2 11.0 26.5 21.1 15.0 5.7 70.5 4.9 25.9 10.4 6.1 26.4 0.0 1.3 18.2 0.6 2.5 0.0 129.9 4.6 6.1 0.9 6.3 1206.2 11.1 2.2 8.8 17.8 1.7 45.7 1.0 12.1 2.3 16.2 9.0 4.1 21.0 18.3 6.1 24.8 6.9 2.3 19.7 4.8 15.6 7.0 4.1 14.4 12.4 30.2 3.5 1.0 8.8 16.3 OSBPL7 "MGC71150, ORP7" ENSG00000006025 "Oxysterol binding protein like 7" Q9BZF2 17 47807372-47821834 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 29.5;Gastric mucus-secreting cells: 118.7;Paneth cells: 29.9;Proximal enterocytes: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036076, HPA053083, HPA073967" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036076: AB_10601042, HPA053083: AB_2682038, HPA073967: " "unprognostic (3.88e-2)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.55e-3)" "unprognostic (2.05e-3)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.08e-1)" "prognostic favorable (1.19e-5)" 5.0 3.7 10.6 4.9 10.4 7.2 5.4 9.5 14.0 11.1 7.3 22.7 22.3 8.6 1.6 3.4 7.6 5.3 6.5 10.3 9.9 9.9 2.2 8.5 7.5 10.6 10.2 9.6 17.3 2.6 10.1 2.3 10.7 14.3 8.7 3.1 9.0 6.1 20.2 1.7 22.7 3.5 9.2 17.2 34.0 1.4 10.5 4.9 11.3 3.5 3.8 9.1 7.0 10.9 6.0 6.9 3.0 3.4 3.3 4.6 2.5 2.2 3.2 3.7 4.2 7.1 17.8 6.0 8.7 3.2 1.3 43.2 1.7 4.8 1.2 20.8 2.4 4.4 15.0 4.8 3.0 9.4 0.1 7.4 0.9 2.4 1.7 11.5 7.7 10.5 4.4 8.1 5.8 7.8 9.5 10.0 1.8 23.8 8.9 8.6 4.7 8.3 5.0 4.5 3.1 7.0 3.7 1.2 3.3 3.7 6.4 5.9 8.9 5.6 4.9 0.0 1.8 14.6 5.8 5.8 6.1 7.9 2.2 0.0 0.6 0.6 1.8 0.4 0.8 1.0 0.7 1.1 0.6 0.4 0.5 0.8 0.3 0.4 0.0 1.0 0.9 0.9 10.6 10.4 9.5 14.0 10.3 9.9 10.6 10.2 10.7 9.2 10.5 10.9 5.5 0.0 3.9 10.4 4.5 0.1 1.1 2.5 1.2 6.1 2.9 2.5 2.7 1.5 7.4 3.7 6.2 0.2 15.4 29.5 0.0 2.7 0.1 2.1 2.7 4.3 6.0 3.2 7.3 14.7 0.1 2.0 118.7 1.7 2.5 7.1 5.3 0.5 2.7 11.8 6.3 25.8 4.1 3.4 0.8 0.3 2.8 2.3 1.8 1.0 2.7 7.1 8.2 3.5 9.3 9.3 29.9 2.6 11.4 1.7 34.5 1.2 3.4 8.2 0.0 2.5 1.9 0.0 0.3 1.3 0.1 0.5 10.0 3.3 17.6 1.3 OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 13.6;lung: 28.4;lymphoid tissue: 29.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 35.6;Kupffer cells: 27.8;Macrophages: 42.9;monocytes: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 36 "classical monocyte: 43.0;eosinophil: 26.6;intermediate monocyte: 28.8;myeloid DC: 20.3;neutrophil: 40.0;non-classical monocyte: 27.0" "Group enriched" "Detected in many" 79 "dendritic cells: 20.3;granulocytes: 40.0;monocytes: 43.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.9;HHSteC: 9.4;hTERT-HME1: 5.0;NB-4: 5.9;U-937: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 84000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" 3.7 1.8 0.9 2.3 0.7 13.6 1.8 0.1 1.6 2.2 0.0 1.5 0.0 1.3 0.0 1.5 3.2 1.3 1.9 0.1 0.7 1.5 2.4 28.4 0.3 1.3 0.7 1.1 1.3 0.1 1.0 0.6 0.9 1.7 0.3 0.0 2.2 0.3 0.5 2.1 1.6 1.7 0.7 29.8 1.2 0.9 0.8 0.2 1.1 0.6 0.6 2.2 2.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 13.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 9.4 0.6 0.0 0.0 0.2 0.6 5.0 0.8 0.0 0.0 0.0 0.4 0.1 0.1 0.0 5.9 0.3 0.1 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.6 0.5 17.9 0.0 0.0 43.0 26.6 0.3 28.8 0.1 0.0 0.2 0.4 20.3 0.0 0.1 0.0 40.0 0.0 27.0 0.8 0.2 16.8 0.9 0.7 0.1 1.6 0.1 0.7 1.3 0.7 0.9 0.7 0.8 1.7 0.2 3.2 5.9 0.3 0.3 0.8 0.6 0.7 0.6 0.0 0.7 0.4 0.3 1.5 2.1 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.1 0.3 0.9 0.0 1.7 1.9 0.0 0.4 0.6 0.0 0.1 1.3 0.3 0.0 0.0 35.6 0.0 1.0 0.3 0.0 27.8 11.6 0.2 0.0 42.9 0.0 1.0 66.4 0.0 1.0 0.0 0.3 0.4 0.0 0.0 0.4 0.3 0.1 0.2 3.7 0.4 0.0 0.2 0.1 0.6 0.5 0.4 0.1 0.3 0.7 0.4 0.1 0.3 OSCP1 "C1orf102, NOR1" ENSG00000116885 "Organic solute carrier partner 1" Q8WVF1 1 36415827-36450451 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 58.0;testis: 76.1" "Cell type enhanced" "Detected in many" "Early spermatids: 453.5;Endometrial ciliated cells: 88.6;Respiratory ciliated cells: 199.1;Spermatocytes: 163.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028436, HPA052655" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA028436: AB_10600885, HPA052655: " "unprognostic (3.46e-3)" "unprognostic (7.57e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.88e-4)" "unprognostic (1.28e-2)" "unprognostic (4.81e-2)" "unprognostic (3.38e-2)" "unprognostic (4.52e-2)" "unprognostic (5.52e-2)" "unprognostic (8.80e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-2)" "prognostic favorable (2.18e-6)" "unprognostic (1.20e-1)" "unprognostic (2.04e-2)" "unprognostic (1.02e-2)" "unprognostic (4.20e-2)" 6.8 8.2 9.7 2.4 10.4 2.0 9.4 7.4 10.5 9.5 31.3 7.3 2.9 10.0 22.0 5.0 58.0 8.8 7.9 11.1 13.0 19.1 2.8 11.0 1.9 11.3 14.7 9.1 8.2 30.2 23.1 5.6 10.9 9.9 3.9 23.1 8.7 8.9 4.9 6.8 2.7 7.9 9.9 1.4 6.3 76.1 13.5 3.6 17.9 5.2 1.5 5.9 4.8 8.3 6.7 6.3 7.6 8.9 8.9 8.6 1.4 4.0 9.7 9.7 6.6 0.1 5.8 1.5 7.3 7.3 7.1 5.1 0.2 7.5 6.2 1.1 5.9 0.1 3.9 0.7 10.9 0.8 1.2 9.8 12.0 13.7 5.9 14.1 6.7 6.3 0.1 1.7 7.7 4.8 3.6 2.5 7.8 2.6 2.6 3.8 3.1 1.2 16.0 2.3 20.4 9.0 7.5 3.5 5.4 7.2 7.6 1.1 5.8 7.0 2.6 12.7 6.9 2.8 3.1 0.8 13.4 0.2 4.7 0.0 0.2 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.6 0.2 0.6 1.0 0.1 0.1 0.0 1.2 0.7 0.2 9.7 10.4 7.4 10.5 11.1 13.0 11.3 14.7 10.9 9.9 13.5 8.3 3.0 9.6 10.9 4.6 0.4 1.5 5.5 21.3 3.4 5.4 7.9 7.5 5.5 5.7 21.3 12.9 16.7 12.2 0.0 2.0 23.5 15.1 453.5 88.6 5.8 3.3 4.9 1.7 8.1 9.3 3.4 6.4 6.1 7.7 0.0 4.8 2.2 2.3 4.2 5.0 6.9 2.3 32.6 0.8 1.2 66.8 12.5 1.4 3.6 1.0 0.1 12.9 0.0 5.0 2.6 7.2 4.0 9.1 0.4 3.5 0.5 26.1 199.1 21.3 0.0 4.7 7.7 163.7 20.6 3.6 3.1 20.1 0.7 13.9 2.3 5.2 OSER1 "C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1" ENSG00000132823 "Oxidative stress responsive serine rich 1" Q9NX31 20 44195939-44210771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 842.5;Late spermatids: 2257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045125 Approved Approved "Nucleoli,Nucleoli rim,Nuclear speckles" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim, Nuclear speckles" "HPA045125: AB_10961629" "unprognostic (2.77e-2)" "unprognostic (3.01e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.18e-1)" "unprognostic (6.07e-2)" "unprognostic (8.44e-3)" "unprognostic (3.31e-1)" "unprognostic (1.14e-1)" "unprognostic (8.78e-2)" "unprognostic (8.01e-3)" "unprognostic (9.87e-2)" "unprognostic (3.96e-1)" "unprognostic (2.14e-1)" "unprognostic (2.45e-1)" "unprognostic (8.39e-2)" "unprognostic (1.06e-1)" 43.4 26.6 22.0 22.3 23.2 128.5 42.3 24.7 26.8 37.2 21.9 39.2 27.2 35.1 30.7 46.2 34.9 23.6 37.5 21.9 24.1 35.7 38.1 36.0 27.7 25.0 23.7 42.5 23.5 29.4 24.3 25.2 24.4 36.7 24.7 25.1 36.9 21.5 110.1 51.8 37.3 25.7 24.1 40.1 32.9 116.3 23.8 25.3 37.7 61.1 32.5 44.6 39.2 27.8 50.6 37.1 28.9 22.6 75.2 54.6 32.7 45.0 69.6 71.0 64.1 93.9 54.7 49.1 44.3 43.3 96.1 73.9 31.8 42.7 59.3 16.2 20.1 16.1 99.8 66.8 41.6 27.6 26.8 64.5 72.3 47.1 86.1 38.7 32.8 30.6 24.9 64.9 40.2 75.8 22.5 35.9 25.7 46.5 39.3 32.8 46.4 35.0 37.3 34.7 28.2 27.5 64.2 90.5 62.2 33.9 45.1 25.6 27.8 60.6 45.3 35.8 39.7 44.3 49.1 48.4 42.6 20.6 31.1 264.8 68.4 119.5 50.0 68.3 54.1 120.1 57.1 49.7 60.7 115.2 67.7 61.8 306.7 67.7 100.2 39.7 73.8 91.5 22.0 23.2 24.7 26.8 21.9 24.1 25.0 23.7 24.4 24.1 23.8 27.8 51.2 19.2 21.0 14.4 70.0 259.4 137.6 95.4 101.3 10.3 69.1 75.2 38.7 18.6 61.3 12.9 4.2 40.4 48.6 58.6 37.2 45.1 842.5 94.7 48.0 36.8 49.5 25.0 9.0 36.4 38.2 48.6 37.2 175.1 33.0 22.9 18.5 27.9 43.4 11.8 9.0 34.6 65.1 30.6 111.1 2257.1 40.7 55.2 76.5 5.6 84.2 31.0 30.9 5.0 12.5 49.3 87.7 35.3 40.6 91.4 68.1 33.5 36.9 14.8 19.7 47.0 45.6 194.8 71.7 50.4 198.5 173.6 55.2 22.3 47.5 119.4 OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108041409-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" 26.1 19.1 4.7 17.9 5.2 5.7 9.8 5.1 5.8 10.4 33.1 12.2 7.9 13.7 9.0 12.7 9.5 12.5 19.2 5.3 9.2 15.6 13.1 16.2 14.7 6.0 7.6 7.5 5.8 15.3 8.3 14.1 7.9 13.8 11.1 17.6 8.9 16.7 11.8 9.8 9.0 23.3 5.3 18.3 8.5 10.1 7.4 13.7 10.7 11.5 13.5 16.9 7.0 8.3 6.0 17.2 20.1 29.4 59.0 19.0 28.6 42.8 42.7 30.7 50.4 10.0 9.8 13.7 34.4 30.0 82.5 11.1 20.2 14.6 47.0 31.6 15.7 28.9 10.9 12.8 45.6 32.1 64.6 28.1 35.7 37.7 30.0 28.2 15.8 15.2 23.3 48.7 50.3 8.4 7.1 7.3 8.0 7.1 13.0 11.4 29.1 7.5 22.0 15.7 2.2 11.8 34.7 8.7 79.9 26.6 10.0 45.8 19.3 26.7 9.8 59.7 61.4 18.6 34.4 11.9 78.9 21.3 60.3 31.4 20.2 22.8 20.3 29.4 21.5 14.7 16.9 22.3 17.8 8.6 15.6 19.8 29.8 22.0 43.5 12.9 22.6 27.0 4.7 5.2 5.1 5.8 5.3 9.2 6.0 7.6 7.9 5.3 7.4 8.3 28.5 9.6 19.0 26.4 26.0 46.7 19.8 11.7 21.6 28.3 10.0 7.0 24.8 12.8 9.4 12.9 10.4 21.7 32.3 21.9 1.9 12.4 12.0 7.5 15.7 20.7 4.2 4.6 36.6 22.9 33.9 24.4 15.8 9.6 24.1 6.9 26.7 13.2 52.8 28.6 40.1 5.8 6.1 46.5 29.5 5.4 14.3 43.1 151.2 20.6 25.6 23.7 40.2 21.1 36.6 16.8 17.0 28.6 25.0 17.9 7.6 25.5 9.8 17.5 26.3 18.5 29.6 28.0 18.7 12.4 31.1 61.2 29.5 23.7 3.3 16.0 OTP ENSG00000171540 "Orthopedia homeobox" Q5XKR4 5 77628712-77638713 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 134 "brain: 28.7" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Sertoli cells: 6.6;Spermatocytes: 2.2;Spermatogonia: 1.5" "Cancer enriched" "Detected in single" 6 "glioma: 1.2" "Region enhanced" "Detected in many" "hypothalamus: 28.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "hypothalamus: 20.0" "Region enhanced" "Detected in some" "hypothalamus: 15.5" HPA059342 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "HPA059342: AB_2732635" "unprognostic (1.00e-1)" "unprognostic (2.40e-2)" "unprognostic (6.25e-2)" "unprognostic (8.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (7.77e-2)" "unprognostic (2.39e-2)" "unprognostic (9.66e-2)" "unprognostic (4.64e-2)" "unprognostic (7.76e-14)" "unprognostic (3.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.49e-3)" 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.1 0.0 9.2 1.7 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.4 0.0 28.7 9.2 1.7 6.6 0.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439075-23442377 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 149.0;Langerhans cells: 219.1;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.1;HaCaT: 36.5;SiHa: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: AB_2676049, HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favorable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 13.0 11.7 8.0 10.2 8.4 60.4 10.3 9.5 10.2 8.4 8.4 8.7 6.8 10.2 6.8 7.8 11.2 9.7 43.4 8.7 9.0 19.7 7.6 19.7 14.4 8.3 8.0 13.6 6.9 19.4 8.0 12.1 7.6 8.8 7.6 5.9 6.7 7.6 29.4 20.9 8.2 9.4 8.4 13.7 22.9 7.5 9.2 6.8 13.3 22.6 12.5 11.9 7.6 9.2 4.8 2.3 2.4 1.1 9.3 4.6 3.2 1.9 4.2 4.4 4.0 0.9 38.1 2.2 4.1 2.4 1.5 36.5 2.5 4.5 2.9 17.4 7.1 0.1 5.7 1.5 8.0 0.4 3.2 4.8 19.4 1.3 6.1 3.9 1.5 2.2 0.5 15.1 2.5 2.3 1.5 1.4 1.9 2.7 1.3 2.4 10.8 2.2 5.8 4.0 1.1 2.6 23.4 4.1 11.3 6.3 1.7 3.3 2.7 2.5 3.7 7.0 0.8 7.6 15.0 1.1 3.8 1.5 1.0 2.5 0.5 1.0 0.3 0.6 0.3 0.7 0.5 0.3 0.3 1.2 0.4 0.6 1.3 0.0 1.9 0.2 1.3 0.2 8.0 8.4 9.5 10.2 8.7 9.0 8.3 8.0 7.6 8.4 9.2 9.2 17.3 67.3 11.5 3.3 55.9 32.0 7.1 5.0 13.6 20.1 12.3 9.1 149.0 7.2 4.9 5.5 2.1 3.3 9.6 47.2 11.7 6.0 8.0 35.0 44.5 25.6 6.0 13.5 4.3 7.1 3.2 20.8 47.4 33.8 5.7 10.4 16.4 10.1 51.0 53.8 4.8 77.9 10.2 68.2 219.1 7.6 6.5 105.7 33.8 8.4 9.3 33.8 10.3 4.0 6.5 10.1 16.3 13.2 50.0 7.7 8.0 25.1 9.8 26.2 6.6 82.2 19.4 7.2 4.7 15.1 30.5 7.9 16.5 7.5 24.3 10.9 OTUD3 "DUBA4, KIAA0459" ENSG00000169914 "OTU deubiquitinase 3" Q5T2D3 1 19882395-19912945 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028543, HPA028544" Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Intermediate filaments" "HPA028543: AB_10599302, HPA028544: AB_10602277" "unprognostic (6.45e-3)" "unprognostic (9.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" "unprognostic (3.16e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-3)" "unprognostic (4.99e-2)" "unprognostic (1.09e-1)" "unprognostic (8.81e-2)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (9.83e-2)" "unprognostic (1.94e-1)" "unprognostic (7.28e-2)" "unprognostic (2.21e-2)" 3.3 5.7 4.8 3.3 5.0 6.4 4.7 5.2 5.9 6.2 2.2 6.4 5.0 7.7 6.0 3.8 5.6 3.3 3.4 4.9 3.2 4.6 3.1 4.9 3.6 2.8 3.1 6.7 4.6 4.1 5.5 2.4 2.8 5.9 3.8 9.3 3.9 4.1 4.9 6.4 5.8 5.6 2.2 4.8 4.8 10.7 3.6 3.7 3.9 4.3 3.0 4.5 4.9 5.2 5.8 2.2 9.5 11.4 4.0 3.5 9.3 6.1 3.5 3.0 3.0 10.2 5.4 9.2 4.8 13.5 2.2 5.6 8.9 3.5 5.9 6.0 11.9 8.8 13.4 7.2 2.2 6.5 7.8 2.9 3.4 4.8 6.2 6.4 4.1 9.2 6.3 3.8 5.3 3.2 5.0 6.5 4.5 4.6 5.6 11.5 24.2 3.4 5.1 6.3 8.4 5.9 4.4 3.5 4.6 9.2 5.2 4.8 5.0 7.3 9.3 8.2 5.3 4.4 4.0 5.6 5.1 8.6 3.4 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.3 0.3 0.1 0.1 0.0 0.1 0.2 0.0 4.8 5.0 5.2 5.9 4.9 3.2 2.8 3.1 2.8 2.2 3.6 5.2 5.0 16.0 7.5 11.4 5.6 14.1 5.9 2.4 4.6 14.9 10.2 9.1 4.7 4.3 2.0 9.2 16.7 2.7 6.5 4.7 0.0 5.1 16.0 11.7 7.8 5.1 12.0 6.1 32.6 4.5 5.4 7.0 5.1 8.3 1.3 16.4 7.9 2.2 1.9 26.9 28.5 7.0 4.1 2.6 8.9 16.4 5.6 5.2 5.4 6.5 4.1 8.9 5.2 21.1 16.6 5.0 6.7 6.0 8.6 9.8 4.7 4.2 9.7 15.5 6.6 7.8 6.1 23.5 21.4 5.7 8.8 2.5 7.0 4.7 7.0 4.8 OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922024-48958386 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 10 "U-266/70: 1503.3;U-266/84: 407.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: AB_1854844" "unprognostic (9.73e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.67e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (6.65e-2)" "unprognostic (2.33e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "prognostic favorable (8.20e-4)" "unprognostic (1.32e-1)" "unprognostic (3.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-2)" "unprognostic (5.05e-3)" 37.7 44.8 42.9 36.9 44.9 56.7 36.6 39.2 45.5 40.6 33.6 45.8 39.6 43.0 29.9 37.5 41.4 24.7 29.9 44.8 46.1 41.1 39.5 39.6 43.4 44.2 42.8 46.8 37.7 35.6 46.1 26.4 46.0 43.1 21.7 30.2 36.3 32.0 39.7 44.6 47.3 27.0 38.3 60.7 37.5 24.2 44.9 47.0 42.3 25.2 35.8 39.9 36.7 43.9 53.0 77.8 36.0 88.9 59.2 52.3 41.4 45.7 52.9 55.9 59.8 39.7 57.3 58.9 29.2 56.8 49.1 63.3 54.2 45.7 51.7 69.1 65.0 44.5 79.4 45.0 49.3 43.4 48.7 58.1 41.2 58.2 39.5 61.4 44.7 47.8 56.9 90.7 40.0 52.3 67.7 89.2 64.9 19.5 60.4 53.0 52.5 77.4 38.9 46.4 34.7 60.7 60.2 38.7 61.7 82.7 51.6 39.2 64.2 36.5 46.2 97.2 38.1 1503.3 407.1 56.5 56.3 58.9 25.7 5.5 3.3 7.6 6.6 5.2 5.6 8.6 5.1 5.7 4.8 5.3 4.8 7.1 8.5 20.3 5.1 6.2 7.3 3.6 42.9 44.9 39.2 45.5 44.8 46.1 44.2 42.8 46.0 38.3 44.9 43.9 21.3 9.6 22.3 17.3 33.3 22.2 21.2 13.7 13.1 35.5 23.7 19.7 11.5 15.7 16.3 27.6 27.1 13.3 38.2 28.4 9.8 13.6 1.9 24.5 23.2 19.6 48.2 32.6 15.5 18.3 16.3 18.4 21.4 33.1 7.0 28.5 22.1 24.3 16.7 28.6 15.7 28.5 10.2 22.9 33.9 2.9 20.8 25.7 26.6 15.9 22.6 18.0 30.9 14.1 14.1 21.5 19.0 23.7 38.1 27.5 28.1 21.7 21.6 27.9 13.1 19.9 20.1 10.4 12.6 15.9 25.6 30.8 33.3 28.6 20.1 27.4 OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU deubiquitinase 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: AB_10600925, HPA024503: AB_1854845, HPA024772: AB_1854846" "prognostic unfavorable (7.50e-4)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (4.78e-3)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.16e-3)" "unprognostic (2.17e-1)" "unprognostic (5.51e-2)" "unprognostic (1.27e-2)" "unprognostic (8.61e-3)" "unprognostic (1.87e-2)" "unprognostic (1.96e-1)" "unprognostic (4.53e-1)" "unprognostic (8.78e-2)" "unprognostic (5.71e-2)" 6.6 6.2 5.7 6.3 6.1 5.9 7.2 5.9 8.6 5.2 5.0 5.3 4.2 6.0 4.6 6.4 4.2 3.9 6.5 5.4 6.1 5.4 5.4 4.7 7.4 6.2 6.2 5.3 4.6 4.0 3.5 8.0 6.3 5.8 5.4 3.1 4.3 4.7 10.2 6.4 4.4 5.5 6.3 5.0 4.3 6.4 5.9 5.7 6.0 9.2 6.1 6.3 5.4 7.5 27.6 11.1 12.8 10.4 6.4 5.6 14.5 19.1 7.4 19.1 12.6 8.6 16.6 25.6 9.0 10.2 7.6 9.1 26.4 16.1 31.6 21.6 16.9 34.5 11.7 8.3 13.3 18.7 21.0 7.2 9.8 14.0 35.5 11.6 17.5 19.4 36.5 19.1 18.9 9.6 31.7 17.5 8.1 20.3 27.3 19.4 11.2 28.9 18.9 15.1 3.5 14.6 2.6 55.9 22.7 16.3 25.5 11.8 15.8 12.3 17.2 20.6 20.5 17.1 29.5 37.2 16.8 26.2 23.1 1.7 1.9 1.1 1.5 2.7 2.0 2.0 1.4 1.7 2.6 1.8 2.1 1.9 0.2 3.4 2.1 4.0 0.8 1.0 5.7 6.1 5.9 8.6 5.4 6.1 6.2 6.2 6.3 6.3 5.9 7.5 11.9 9.6 11.3 9.8 13.7 23.2 6.5 4.0 10.8 13.0 6.5 5.2 14.3 8.6 9.2 1.8 33.3 10.8 16.5 5.1 9.8 4.8 0.9 10.6 9.9 10.9 10.8 8.2 18.0 4.9 10.0 9.0 7.7 8.6 18.4 10.7 8.9 11.7 8.1 11.8 15.5 4.9 4.1 8.7 12.5 2.2 9.6 8.3 3.6 12.2 10.2 12.2 11.3 18.6 21.6 6.6 3.7 4.1 12.0 8.9 2.8 8.2 8.8 15.3 0.0 8.2 9.6 3.2 7.0 12.5 18.2 6.7 10.7 9.9 6.4 5.9 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Oligodendrocytes: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: AB_1854847, HPA076357: " "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favorable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favorable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 11.7 7.7 21.0 3.8 39.2 1.1 7.8 28.7 18.5 9.9 6.8 7.6 6.2 10.5 3.8 7.7 9.3 4.8 7.1 15.3 22.1 5.6 10.7 7.3 1.9 41.4 37.2 10.9 6.1 10.9 3.4 7.1 35.5 6.6 7.1 10.1 7.8 7.5 18.6 5.8 6.2 10.8 27.9 3.6 6.7 12.7 31.7 2.1 6.7 16.2 3.2 6.3 5.2 43.0 17.2 13.5 9.3 15.6 12.0 11.1 8.8 11.8 17.3 14.0 9.6 10.0 13.6 0.2 7.5 21.7 6.3 13.4 13.2 13.1 14.6 16.5 6.7 6.6 18.9 6.8 12.8 7.6 6.9 12.4 9.9 23.7 20.6 10.9 11.5 2.0 18.4 18.1 10.1 17.5 1.3 2.1 11.9 12.8 13.1 1.8 12.9 4.4 5.4 23.2 6.0 11.4 20.8 15.2 18.5 12.1 12.6 4.0 13.9 14.4 13.2 9.8 14.0 19.1 20.0 2.0 12.8 2.2 24.1 2.0 0.0 0.4 0.7 0.0 0.5 0.1 0.3 0.4 0.0 0.1 0.2 0.3 0.3 0.4 0.0 0.1 0.1 0.0 21.0 39.2 28.7 18.5 15.3 22.1 41.4 37.2 35.5 27.9 31.7 43.0 10.2 35.3 11.7 56.8 3.0 15.9 22.7 8.7 13.1 28.0 18.3 9.3 22.2 12.8 15.3 11.0 106.3 23.5 5.1 41.1 7.9 14.5 63.4 21.8 17.8 16.7 17.4 14.9 20.6 11.1 11.6 14.8 21.4 40.2 0.0 22.0 20.3 33.0 3.1 23.5 24.6 15.8 8.2 0.8 5.9 79.4 14.6 2.4 37.4 22.5 4.3 23.6 15.5 33.2 176.8 20.6 21.3 23.0 4.7 20.2 17.1 11.5 17.4 66.9 0.0 19.8 17.9 11.1 7.2 11.8 16.6 21.2 7.5 11.1 11.1 34.0 P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 80.3;Granulosa cells: 124.1;Microglial cells: 91.8;Theca cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 90 "dendritic cells: 28.9" "Cell line enhanced" "Detected in many" "GAMG: 120.2;HaCaT: 109.9;RPTEC TERT1: 109.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" 4.9 41.6 2.8 4.9 3.1 1.0 6.5 3.0 3.1 17.0 1.8 24.0 2.7 17.6 18.5 11.0 8.0 4.8 8.8 3.3 4.8 51.3 7.0 28.7 2.4 7.6 4.7 16.1 3.6 2.3 8.2 9.2 6.7 37.6 10.4 19.3 4.9 26.5 1.2 17.8 6.7 32.4 5.2 54.8 23.9 4.2 4.9 5.2 3.0 1.7 2.0 11.9 19.9 8.3 46.9 18.2 35.1 0.2 0.6 1.4 42.1 48.7 19.3 7.8 12.6 15.0 18.0 0.1 27.1 8.6 120.2 109.9 0.1 65.3 16.3 0.4 6.2 0.1 12.1 0.3 35.4 0.2 0.3 16.9 21.4 15.2 5.4 73.5 1.4 0.1 0.1 0.4 12.3 1.1 0.1 0.4 11.0 31.3 3.7 0.1 7.1 2.8 109.8 77.5 2.5 0.3 66.1 3.7 29.3 51.1 0.1 0.7 24.4 45.9 16.8 0.4 8.9 3.4 0.2 0.5 10.6 0.2 60.2 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.1 0.0 28.9 0.0 0.2 2.8 3.1 3.0 3.1 3.3 4.8 7.6 4.7 6.7 5.2 4.9 8.3 5.7 48.1 80.3 19.2 1.0 0.0 7.7 0.0 13.6 2.3 1.6 9.9 1.0 2.8 3.1 44.1 4.2 42.0 9.5 19.8 5.9 4.7 19.6 2.0 27.3 10.5 0.0 2.7 55.6 0.8 14.7 10.3 8.6 1.5 1.3 124.1 32.5 0.8 11.4 10.1 60.4 0.5 0.0 3.2 0.0 14.9 4.7 5.6 0.0 91.8 0.8 44.5 0.0 43.7 4.4 30.6 1.9 0.0 0.2 15.1 0.0 26.2 0.0 1.2 0.0 10.9 45.2 0.5 0.9 13.5 0.0 38.6 0.7 74.3 2.1 3.9 P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Cone photoreceptor cells: 100.1;Horizontal cells: 43.7;Leydig cells: 49.7;Peritubular cells: 38.4;Rod photoreceptor cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 39.6;hTERT-RPE1: 27.3;NTERA-2: 27.5;U-251 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 740000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" 3.5 2.6 1.2 1.5 0.7 0.3 3.9 3.7 2.7 11.9 5.6 5.4 0.8 19.2 0.5 1.6 9.9 1.7 4.5 1.1 1.2 2.0 0.6 3.7 0.3 1.3 0.2 12.4 2.9 4.5 15.4 1.3 0.3 6.0 0.3 4.1 6.5 3.7 0.8 3.0 2.8 3.8 0.2 1.3 3.8 1.2 0.9 0.1 4.3 0.3 0.3 7.8 6.4 0.5 0.0 1.6 7.1 14.0 8.4 10.2 0.3 39.6 22.4 12.2 13.5 0.6 0.0 0.0 0.5 14.9 0.5 0.0 4.4 0.4 2.7 0.1 18.8 1.0 4.2 1.9 5.9 1.0 0.0 11.1 0.4 6.0 3.3 27.3 13.1 1.2 3.7 0.0 5.7 0.0 0.1 0.4 27.5 0.0 1.1 0.0 6.9 0.2 0.6 0.0 2.8 10.5 0.1 0.0 4.8 3.4 0.2 0.2 23.2 12.0 17.5 18.6 27.7 0.1 0.3 0.3 10.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 3.7 2.7 1.1 1.2 1.3 0.2 0.3 0.2 0.9 0.5 2.3 0.0 0.0 3.3 0.5 0.0 4.9 0.0 2.2 47.2 5.3 5.5 11.1 1.5 1.8 5.5 100.1 0.5 0.1 0.1 1.9 1.4 0.9 0.9 19.6 3.9 1.2 0.0 13.1 2.7 0.5 24.1 2.0 0.4 0.0 0.8 7.9 0.0 1.4 43.7 13.7 2.7 0.0 0.0 0.0 2.2 49.7 0.5 0.0 2.8 1.1 5.3 0.0 5.5 1.3 1.3 0.1 38.4 3.1 5.1 0.4 0.4 1.5 28.8 6.6 7.8 11.9 0.7 0.8 0.8 0.0 1.0 0.9 3.2 0.6 1.5 P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 494.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Yes No 60000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: AB_1854891, HPA026593: AB_1854892" "prognostic unfavorable (9.01e-4)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.15e-2)" "prognostic unfavorable (9.40e-9)" "unprognostic (3.14e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "unprognostic (5.75e-2)" 28.1 26.0 25.7 20.8 26.4 15.5 26.3 29.6 58.5 31.9 34.7 16.3 11.0 27.0 18.9 10.1 41.1 26.3 38.7 26.5 27.1 35.8 72.8 27.8 16.2 32.9 30.0 34.9 17.5 17.0 11.6 65.3 33.0 20.0 17.4 33.3 13.0 18.4 110.9 17.4 14.4 28.5 30.2 19.6 19.8 19.3 30.1 12.9 13.9 54.0 14.6 29.6 18.2 39.0 84.0 21.2 60.1 117.6 181.2 138.3 50.1 239.9 215.8 90.8 215.8 35.6 63.6 28.4 89.7 239.0 55.1 92.5 38.3 87.7 197.1 36.5 14.5 24.4 18.6 42.5 75.3 45.1 16.4 84.5 50.3 77.7 101.6 494.2 43.5 23.8 38.3 14.7 79.3 22.4 17.9 42.9 21.6 38.9 92.3 16.4 40.2 52.4 51.0 35.6 5.5 33.7 49.2 143.2 58.3 135.0 21.9 41.9 41.9 110.5 44.8 31.3 56.9 81.8 31.3 13.7 198.1 64.5 54.9 1.1 18.8 14.9 6.7 23.5 8.7 8.2 8.1 7.9 20.7 9.2 5.9 6.1 10.4 5.2 25.7 16.6 10.7 9.1 25.7 26.4 29.6 58.5 26.5 27.1 32.9 30.0 33.0 30.2 30.1 39.0 29.0 6.4 28.4 87.1 31.7 36.3 33.0 138.0 22.2 13.5 23.8 15.7 42.0 7.2 69.2 23.9 27.1 31.5 24.9 25.1 0.0 33.1 16.8 85.6 89.2 25.9 10.3 7.2 48.8 19.5 116.4 67.7 14.3 131.4 40.5 16.9 20.0 29.8 43.9 11.8 41.6 9.5 46.8 54.1 75.7 8.1 51.9 51.5 44.4 62.8 39.0 34.0 6.2 86.5 44.8 36.6 27.1 47.0 32.9 24.9 13.5 25.1 94.6 17.2 39.5 37.0 44.7 61.7 34.0 9.8 23.9 33.2 27.7 31.1 7.0 17.6 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 250000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 23.1 34.3 35.1 21.2 42.2 41.2 20.6 43.9 45.0 20.8 28.4 21.7 22.4 23.8 22.7 23.9 20.9 19.9 28.2 33.9 45.4 25.3 23.8 21.7 20.7 47.6 45.0 23.3 20.3 21.9 24.5 25.4 51.0 22.3 20.0 23.2 17.4 16.1 15.7 22.0 19.4 20.4 48.7 20.4 23.0 30.0 43.6 21.5 31.9 20.3 22.2 26.9 20.9 51.6 43.4 48.5 54.9 79.7 60.1 41.7 42.6 71.0 61.7 38.8 35.2 89.2 92.9 46.6 99.4 85.8 38.7 67.7 80.6 92.0 50.9 41.8 31.1 120.0 41.3 57.9 53.8 42.1 44.0 46.6 71.7 77.4 96.7 42.4 64.8 25.6 65.0 34.6 60.3 27.7 40.8 61.7 50.4 60.0 37.8 44.9 62.2 51.2 59.8 66.7 60.9 80.5 82.2 61.6 28.1 46.6 68.4 35.6 103.8 70.4 46.3 34.8 51.4 10.8 17.9 61.5 28.3 78.8 60.4 63.4 51.4 48.6 39.0 58.7 46.4 43.8 44.7 41.0 37.4 41.2 45.8 49.2 63.7 33.1 66.3 27.4 35.1 53.1 35.1 42.2 43.9 45.0 33.9 45.4 47.6 45.0 51.0 48.7 43.6 51.6 48.5 28.9 34.8 17.9 41.4 122.4 44.5 45.9 54.7 38.6 55.4 32.1 37.6 58.6 32.8 66.2 47.9 40.4 44.4 48.0 46.9 61.3 13.1 63.6 54.8 64.8 82.6 39.4 29.2 39.5 86.7 40.8 33.6 78.4 19.0 36.8 79.6 47.0 43.0 47.1 32.5 41.8 36.7 65.4 175.9 13.7 45.4 52.1 49.8 20.6 59.3 36.2 21.6 13.0 61.2 99.0 50.5 34.3 28.9 67.0 33.7 54.8 32.9 38.3 13.1 42.8 40.0 54.7 84.7 53.2 115.9 54.6 41.6 35.2 45.4 50.6 PAGE1 "CT16.3, GAGE-9, GAGEB1, PAGE-1" ENSG00000068985 "PAGE family member 1" O75459 X 49687447-49695984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 151 "testis: 17.2" "Group enriched" "Detected in some" 5 "Spermatocytes: 166.9;Spermatogonia: 206.5" "Group enriched" "Detected in many" 4 "liver cancer: 10.5;melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 188.0;Karpas-707: 139.8;U-266/84: 230.7" HPA003473 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Mitochondria" "HPA003473: AB_1079558" "unprognostic (3.00e-1)" "unprognostic (1.99e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.7 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 139.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.4 0.3 0.2 0.3 1.6 0.6 2.8 230.7 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 166.9 206.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40217428-40277487 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.6;skin 1: 28.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;NK-cells: 16.5;Suprabasal keratinocytes: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 26.5;HaCaT: 32.2;hTCEpi: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.2 8.2 11.6 0.4 15.9 0.9 2.1 8.5 16.6 4.5 0.0 1.3 1.5 0.9 1.0 25.6 4.3 1.1 8.3 17.6 3.0 4.7 0.3 2.5 0.9 1.4 1.1 0.6 8.0 8.0 12.1 7.6 1.9 4.4 1.1 0.8 6.1 3.8 4.5 28.2 1.5 0.3 1.8 0.9 3.9 17.7 3.0 0.5 7.5 1.3 1.9 3.5 9.4 5.4 3.9 0.0 0.2 0.0 0.0 0.0 6.0 0.0 0.2 0.7 0.7 26.5 2.9 0.1 3.6 0.0 1.3 32.2 4.5 6.9 0.3 0.2 1.0 0.0 3.0 0.2 0.0 0.1 0.3 0.0 19.4 0.3 4.5 0.2 0.0 5.5 1.8 0.3 0.0 4.5 0.0 0.5 0.5 3.9 2.9 0.2 0.2 2.9 1.5 8.4 7.3 2.0 2.6 10.9 0.3 1.7 1.7 10.3 0.0 0.3 0.6 0.0 0.3 0.1 0.3 0.1 0.7 0.6 0.2 1.2 0.1 1.2 2.3 0.1 0.8 0.6 0.1 1.9 0.3 0.1 0.1 0.4 0.5 0.9 0.1 0.1 0.0 0.6 11.6 15.9 8.5 16.6 17.6 3.0 1.4 1.1 1.9 1.8 3.0 5.4 0.0 0.0 4.2 0.7 0.3 9.8 9.6 4.8 8.6 3.5 2.8 2.9 0.0 4.3 5.4 5.5 0.0 52.7 2.1 0.3 13.7 4.4 8.6 3.3 0.4 0.3 4.9 0.0 8.9 4.3 3.0 0.7 0.5 5.1 0.0 0.7 0.0 0.0 4.1 0.0 7.3 1.1 2.0 0.6 0.9 5.8 1.8 0.3 1.8 1.0 0.0 1.3 16.5 0.5 0.3 2.5 1.0 1.9 0.1 5.2 0.2 0.2 3.9 0.2 0.0 0.3 0.4 1.9 3.3 13.9 19.0 9.0 1.0 0.8 2.0 11.3 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA058905: AB_2683851, HPA074153: AB_2686669, HPA076866: " "unprognostic (7.12e-2)" "unprognostic (1.64e-6)" "unprognostic (7.90e-2)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" "unprognostic (3.19e-1)" "unprognostic (9.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.75e-1)" "unprognostic (8.37e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-3)" "unprognostic (7.77e-2)" "unprognostic (1.98e-4)" "unprognostic (3.36e-5)" 97.0 13.5 21.8 37.3 21.1 9.9 17.5 6.9 22.7 28.5 0.0 17.4 14.8 28.8 8.5 26.5 14.7 37.4 93.8 15.7 18.5 30.8 38.2 69.1 32.2 18.1 26.6 9.3 13.1 14.0 0.1 97.9 20.3 14.9 18.1 3.3 38.0 25.1 17.0 10.1 13.3 48.5 10.5 38.4 18.5 4.6 38.8 45.4 25.6 24.3 31.7 43.0 0.4 26.3 20.6 7.7 112.5 0.1 110.8 93.0 33.4 116.0 141.3 101.6 93.4 134.6 17.9 92.1 30.6 129.6 146.2 28.9 9.5 98.8 185.4 68.9 12.5 9.2 30.4 11.0 75.9 12.4 256.2 109.8 24.7 183.3 280.4 62.5 150.9 14.5 0.3 76.2 204.7 1.2 61.9 31.1 47.2 9.1 62.6 5.5 98.2 25.3 72.4 2.8 25.2 1.5 10.3 9.5 26.4 87.8 4.1 22.2 240.0 94.0 77.9 137.5 108.8 52.5 89.1 52.5 81.4 51.3 73.9 2.9 0.1 1.3 1.0 0.2 0.2 10.6 1.2 1.4 1.2 10.3 0.7 0.8 0.5 2.2 0.0 2.4 3.9 1.4 21.8 21.1 6.9 22.7 15.7 18.5 18.1 26.6 20.3 10.5 38.8 26.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PALM3 ENSG00000187867 "Paralemmin 3" A6NDB9 19 14053363-14062076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.9;liver: 55.7;stomach 1: 30.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 40.9;Cholangiocytes: 22.8;Collecting duct cells: 38.6;Exocrine glandular cells: 27.9;Hepatocytes: 40.5;Spermatogonia: 18.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AN3-CA: 17.6;CACO-2: 20.2;GAMG: 5.5;HAP1: 15.8;NTERA-2: 10.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052794, HPA056119" Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA052794: AB_2681952, HPA056119: AB_2683042" "unprognostic (3.67e-2)" "unprognostic (9.08e-2)" "unprognostic (4.72e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.14e-2)" "unprognostic (1.47e-1)" "unprognostic (4.66e-2)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (3.91e-1)" "unprognostic (3.93e-2)" "unprognostic (3.88e-2)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.72e-3)" 0.1 0.2 1.3 0.1 1.4 0.0 0.6 1.3 1.5 2.0 1.0 0.8 1.6 1.0 6.7 0.3 1.8 1.0 0.4 1.3 1.8 46.9 55.7 4.3 0.0 2.9 1.7 0.2 24.5 6.5 0.4 0.4 2.6 4.0 0.2 0.5 3.7 4.5 0.1 0.5 1.1 0.0 1.7 0.1 30.5 15.2 1.8 0.0 12.7 0.0 0.0 4.7 1.6 1.7 1.4 1.3 2.9 17.6 0.3 0.0 3.3 0.3 0.0 0.7 0.5 20.2 0.3 0.0 0.2 0.4 5.5 0.0 15.8 0.0 0.3 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.5 0.0 0.0 3.4 0.0 0.0 3.2 0.2 0.0 10.3 1.6 0.8 0.0 0.0 0.0 0.0 1.7 1.9 2.3 0.1 0.0 0.0 3.2 1.3 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 1.3 1.5 1.3 1.8 2.9 1.7 2.6 1.7 1.8 1.7 0.1 57.7 40.9 0.3 0.5 0.0 0.6 0.1 0.0 0.7 1.0 1.4 0.3 22.8 10.1 38.6 0.0 0.3 0.0 0.7 1.9 9.4 0.0 3.2 1.0 0.2 1.2 0.0 0.3 27.9 3.1 1.7 7.1 6.3 1.3 0.1 1.8 40.5 0.1 0.0 0.5 3.0 0.0 1.3 0.3 0.5 0.9 0.2 1.8 0.0 1.0 0.8 0.0 0.0 0.1 5.5 1.3 2.6 0.0 1.0 3.2 9.5 2.1 0.6 0.0 0.1 0.2 0.0 18.8 0.0 0.0 2.2 0.3 0.0 1.0 1.0 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PAM16 "Magmas, Tim16, TIMM16" ENSG00000217930 "Presequence translocase associated motor 16" Q9Y3D7 16 4331549-4355607 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 109.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Gastric mucus-secreting cells: 36.2;Plasma cells: 39.5;Squamous epithelial cells: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 184.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062721 Approved Nucleoplasm,Microtubules,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" Microtubules "HPA062721: AB_2684849" "unprognostic (2.69e-2)" "unprognostic (1.64e-1)" "unprognostic (4.06e-1)" "unprognostic (6.81e-2)" "unprognostic (6.98e-2)" "unprognostic (9.68e-2)" "unprognostic (1.83e-1)" "unprognostic (6.32e-2)" "unprognostic (1.99e-1)" "unprognostic (1.39e-1)" "unprognostic (4.79e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (5.73e-5)" "unprognostic (7.25e-2)" "unprognostic (2.22e-1)" "unprognostic (3.56e-1)" "prognostic favorable (1.33e-4)" 26.2 44.3 16.2 6.4 16.9 14.4 24.5 14.8 29.0 21.8 15.6 23.8 14.9 20.5 7.0 25.9 22.3 3.9 70.7 16.4 16.2 28.7 66.4 22.4 7.6 15.5 15.9 20.0 39.2 7.4 27.7 6.2 15.6 20.6 4.8 4.7 19.1 8.2 109.3 21.5 19.6 5.1 14.9 22.4 26.8 34.5 15.9 5.8 17.9 17.6 6.1 26.2 20.7 16.2 20.7 41.2 13.8 41.1 5.2 15.2 44.1 34.3 9.8 23.3 15.5 39.0 28.5 49.4 43.7 10.6 22.6 28.5 12.0 16.3 5.5 56.1 87.8 44.8 26.0 20.4 23.4 33.0 34.6 17.7 27.6 17.2 13.0 12.5 13.2 44.1 68.9 24.8 13.2 57.1 40.1 92.8 41.6 16.2 71.5 54.5 18.6 61.5 10.0 12.8 61.8 49.6 32.7 31.7 52.4 8.3 25.7 54.0 13.2 26.0 41.9 184.8 49.7 34.0 46.7 71.1 15.3 30.3 34.8 0.3 25.0 3.2 17.9 16.2 17.0 26.0 16.3 16.4 17.5 23.2 20.0 20.7 14.3 18.3 18.1 33.2 21.7 18.9 16.2 16.9 14.8 29.0 16.4 16.2 15.5 15.9 15.6 14.9 15.9 16.2 2.6 3.2 4.8 0.0 12.8 4.0 1.4 6.9 67.2 0.8 9.8 7.7 0.5 10.0 5.0 0.0 0.0 2.3 3.7 1.8 7.9 4.0 3.3 14.3 11.9 4.4 0.0 18.5 0.0 3.1 2.8 7.0 36.2 10.0 1.3 12.0 3.3 14.6 1.6 1.7 0.0 2.6 2.0 4.3 1.5 2.2 5.0 6.9 1.8 0.0 4.5 0.4 0.0 0.0 0.0 4.8 2.5 3.8 39.5 1.2 5.5 7.3 5.1 0.6 6.6 2.0 5.1 9.7 13.7 81.3 5.8 1.2 8.8 1.7 3.5 1.3 PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720234 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 444.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 321.8;eosinophil: 359.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 359.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 13000 "Cluster 2: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA049781: AB_2680879" "unprognostic (1.36e-2)" "unprognostic (5.03e-2)" "prognostic favorable (9.14e-4)" "prognostic favorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.70e-5)" "unprognostic (1.58e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (1.42e-1)" "unprognostic (5.76e-2)" "unprognostic (6.23e-3)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" 26.3 14.2 36.8 30.8 43.9 26.0 49.9 46.4 50.0 49.6 26.5 20.4 16.0 47.1 43.0 36.2 48.4 26.4 15.9 41.9 40.8 31.7 10.3 44.4 32.9 53.2 41.4 29.2 49.3 26.9 15.8 17.2 51.8 41.1 24.7 22.3 66.0 25.9 6.1 49.7 15.8 33.6 51.1 17.4 62.8 17.0 41.8 35.4 20.3 9.9 51.7 31.7 23.7 66.3 33.6 29.7 49.1 62.1 59.1 74.0 39.6 42.4 77.2 39.4 53.1 45.7 46.7 51.3 26.0 76.1 30.4 40.7 46.8 81.6 50.5 124.2 35.5 60.4 62.6 103.0 32.3 93.0 99.8 61.7 41.2 45.7 37.1 95.2 88.7 63.9 13.6 97.0 111.6 50.7 77.3 28.2 52.6 35.3 33.1 62.4 78.0 15.0 59.6 45.6 55.5 81.4 42.9 63.3 51.9 61.9 37.9 14.1 52.9 49.3 51.0 33.6 35.4 76.9 57.2 48.7 60.1 69.3 79.2 321.8 49.9 359.8 15.6 56.2 18.8 44.8 21.2 18.0 51.4 26.4 13.2 14.9 55.5 27.6 60.8 9.8 39.9 36.7 36.8 43.9 46.4 50.0 41.9 40.8 53.2 41.4 51.8 51.1 41.8 66.3 19.7 96.1 20.2 41.4 25.4 32.0 36.3 73.2 33.6 19.9 48.4 41.5 7.4 50.1 92.3 57.0 10.4 20.6 7.0 10.5 17.6 36.8 6.2 124.2 84.6 25.1 23.4 15.3 112.2 44.7 48.7 35.2 62.2 444.3 42.5 25.0 20.3 10.2 55.1 30.3 64.7 17.5 32.6 46.5 27.8 6.7 18.0 53.5 60.5 29.0 37.4 35.0 10.3 100.0 150.3 33.6 9.1 25.6 86.4 29.1 6.9 28.8 110.0 13.3 26.3 45.2 29.1 19.6 14.7 62.9 40.9 8.9 22.2 19.2 14.8 29.4 PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 42.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 266.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.9;RPMI-8226: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009733, HPA041551" Approved Supported "Cell Junctions,Actin filaments,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions, Actin filaments" Cytosol "CAB009733: AB_2159676, HPA041551: AB_2677545" "prognostic favorable (5.40e-4)" "unprognostic (6.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-3)" "unprognostic (9.13e-2)" "prognostic favorable (3.08e-7)" "unprognostic (9.22e-3)" "unprognostic (6.69e-2)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" 3.2 8.0 25.1 2.4 24.8 1.3 2.8 32.4 38.5 2.1 19.3 7.7 1.1 2.6 2.1 2.0 2.7 1.9 4.2 28.1 22.3 8.8 6.5 3.1 3.1 25.3 22.8 3.9 27.9 6.6 30.2 0.7 26.8 3.6 1.0 2.7 2.7 2.7 8.7 1.8 4.1 1.6 21.9 4.8 5.9 42.9 25.8 3.4 2.4 5.3 2.2 3.7 1.7 25.4 8.9 9.4 2.6 23.5 1.7 0.4 4.7 0.2 1.1 3.4 3.2 4.7 3.6 14.8 4.3 0.3 1.2 7.0 5.2 1.1 0.7 6.9 5.0 6.0 4.1 5.5 2.4 2.5 13.5 0.1 0.5 3.2 1.3 2.1 1.7 21.7 0.6 3.4 0.6 8.7 15.6 3.2 3.3 12.0 6.0 27.9 1.7 24.5 8.8 5.1 21.8 11.7 1.4 3.2 3.7 0.7 19.9 0.9 1.4 0.3 0.8 2.1 4.6 3.5 12.1 13.5 2.6 5.3 1.0 2.1 0.9 0.4 4.3 0.6 7.8 10.9 5.9 5.4 1.1 8.3 2.8 2.2 3.4 1.3 0.1 5.1 6.3 2.0 25.1 24.8 32.4 38.5 28.1 22.3 25.3 22.8 26.8 21.9 25.8 25.4 4.4 3.2 5.8 2.0 17.0 0.9 2.2 1.6 1.2 11.1 7.7 6.7 1.7 10.0 2.6 20.2 4.2 5.7 8.2 3.5 33.2 7.2 61.0 4.1 0.5 3.2 34.0 4.0 7.2 15.0 0.4 3.3 6.1 2.7 5.7 5.2 3.9 4.6 4.3 32.0 7.3 3.3 0.0 4.1 5.7 266.5 3.7 4.7 5.4 3.7 2.2 19.1 1.0 2.0 2.2 6.0 2.1 1.5 12.1 2.1 2.9 16.3 3.4 10.1 0.0 8.0 9.7 5.5 3.9 1.4 1.6 2.9 15.0 1.9 4.7 2.4 PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA053007" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA021819: AB_1854974, HPA053007: AB_2682014" "unprognostic (5.77e-3)" "unprognostic (6.74e-2)" "unprognostic (3.06e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.57e-5)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (8.34e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (5.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (8.54e-2)" "unprognostic (1.13e-1)" 5.3 6.5 3.7 6.2 3.8 3.2 7.1 7.5 4.8 6.1 1.4 7.3 8.8 6.1 4.7 7.0 5.8 5.4 8.5 4.0 4.3 12.7 6.9 5.2 9.1 3.6 3.2 5.4 4.0 8.9 4.3 7.7 4.0 6.7 7.8 5.8 5.3 6.3 12.0 7.3 7.0 6.3 3.0 6.9 6.4 7.8 3.7 9.1 6.7 9.0 9.0 6.2 5.2 4.3 15.3 9.5 20.0 17.8 11.2 13.6 14.9 13.6 17.2 17.0 16.1 9.8 15.2 10.5 10.7 13.3 7.8 17.7 17.3 10.2 19.8 15.5 16.6 11.6 7.7 13.2 13.8 16.5 8.9 8.4 21.0 12.3 22.4 13.4 10.6 14.0 18.8 11.1 14.9 9.2 18.0 20.0 22.4 10.5 26.8 21.1 20.7 13.9 16.1 8.4 16.0 19.7 10.6 21.6 17.1 21.2 23.8 10.9 10.0 11.5 12.4 11.8 15.9 10.4 16.2 21.9 18.9 18.8 8.8 6.1 2.5 1.4 2.3 2.2 3.2 3.0 3.0 2.8 2.7 2.9 3.7 3.5 1.3 3.9 3.5 2.9 2.8 2.3 3.7 3.8 7.5 4.8 4.0 4.3 3.6 3.2 4.0 3.0 3.7 4.3 8.2 9.6 15.3 22.2 12.2 6.1 5.2 4.3 12.0 13.9 9.5 7.4 28.6 14.3 9.2 12.9 27.1 7.7 8.9 10.4 9.8 7.3 6.1 17.7 14.8 11.1 6.6 12.8 42.5 6.5 6.2 12.0 11.2 11.8 14.5 17.0 6.8 13.6 9.7 5.0 37.9 10.0 2.0 12.0 4.3 4.6 7.5 11.6 3.6 35.6 12.4 7.3 24.7 26.7 41.4 8.1 3.7 8.2 9.9 5.3 8.7 40.3 21.5 20.7 0.0 11.3 12.0 17.1 13.3 13.8 6.0 4.7 12.0 20.0 11.2 4.4 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PARP10 "ARTD10, FLJ14464" ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028122, HPA052427" Approved Supported "Nucleoli rim,Golgi apparatus,Cytosol" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli rim" "Golgi apparatus, Cytosol" "HPA028122: AB_10601979, HPA052427: AB_2681828" "unprognostic (9.80e-3)" "unprognostic (5.89e-2)" "unprognostic (2.63e-3)" "unprognostic (9.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (4.69e-3)" "unprognostic (1.09e-3)" "unprognostic (4.17e-2)" "unprognostic (8.69e-2)" "unprognostic (5.30e-3)" 25.2 34.9 10.0 36.3 10.6 23.7 24.6 9.8 13.2 31.8 10.4 33.2 28.4 29.1 3.7 21.5 35.7 9.9 13.8 9.0 10.4 38.4 39.7 34.7 35.8 16.0 11.0 40.6 21.7 6.2 26.0 10.2 12.5 35.7 4.9 6.4 38.3 16.6 18.3 23.1 35.4 7.3 13.3 61.2 25.6 35.4 12.3 34.2 29.4 4.5 10.6 17.8 25.1 11.9 17.8 1.8 1.2 3.3 8.4 7.3 9.3 3.0 3.7 18.7 21.0 0.9 29.6 21.9 39.8 9.2 21.4 6.7 0.4 10.1 0.8 49.5 0.1 24.1 10.8 11.0 7.8 9.5 27.7 4.7 9.9 9.3 3.8 2.1 2.9 30.6 0.4 16.9 3.7 21.4 33.4 16.5 1.0 0.2 13.9 30.8 3.5 29.4 7.7 21.6 1.0 1.1 19.8 2.0 38.8 0.4 22.0 13.9 13.1 9.6 14.2 16.4 10.9 28.4 18.3 5.1 13.9 31.6 5.3 0.0 2.4 3.6 4.4 2.8 2.7 1.1 2.1 3.6 2.3 2.0 1.5 2.4 1.0 1.8 2.8 16.5 1.5 3.5 10.0 10.6 9.8 13.2 9.0 10.4 16.0 11.0 12.5 13.3 12.3 11.9 22.3 3.2 5.2 10.4 19.1 7.6 8.2 10.7 17.6 5.7 12.3 16.0 3.2 7.2 6.3 9.2 14.6 2.2 42.2 20.5 1.9 9.2 6.2 12.0 12.7 10.7 19.2 5.7 0.4 5.6 4.0 12.7 23.9 13.3 19.1 25.9 9.3 21.1 12.0 0.0 0.6 17.3 6.1 16.6 6.8 7.9 15.8 21.4 7.2 12.2 25.8 13.4 34.0 4.5 1.0 6.5 13.8 11.3 15.2 4.5 22.0 25.1 6.7 20.4 6.6 11.7 13.4 19.6 9.1 10.4 4.7 1.4 27.0 17.7 16.4 4.0 PARP11 "ARTD11, C12orf6" ENSG00000111224 "Poly(ADP-ribose) polymerase family member 11" Q9NR21 12 3791047-3873448 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Protein transport, Spermatogenesis, Translocation, Transport" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 61.5;Granulosa cells: 72.0;Late spermatids: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026895 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026895: AB_1854980" "unprognostic (9.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.53e-1)" "unprognostic (2.61e-1)" "unprognostic (3.58e-2)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (2.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.81e-2)" "unprognostic (2.87e-2)" 3.4 5.0 2.7 5.0 2.9 3.2 5.3 2.0 2.9 4.2 2.0 3.6 3.7 6.5 5.4 3.1 4.1 4.0 2.3 2.5 3.4 3.9 4.5 3.8 10.2 3.4 3.2 8.2 2.5 7.8 1.8 3.2 3.3 8.6 4.1 3.3 4.0 4.2 1.8 2.2 3.7 5.2 2.8 6.2 3.3 9.4 3.5 10.4 9.1 2.9 9.4 5.0 1.9 3.5 2.7 2.3 14.0 2.3 4.4 7.2 4.1 3.3 5.5 5.6 5.7 8.7 2.2 8.0 2.0 6.4 6.6 2.2 4.8 4.8 9.0 16.1 4.9 12.0 0.0 6.5 5.1 8.1 4.4 5.9 3.8 4.4 12.4 0.0 4.4 15.3 3.1 6.5 8.1 4.0 4.2 3.1 5.2 2.9 0.3 8.3 9.8 1.8 2.6 6.3 0.9 2.9 3.1 2.8 4.2 15.1 0.5 7.1 8.5 4.9 4.8 7.3 4.4 3.1 7.3 11.7 4.6 4.4 1.2 20.3 8.9 9.2 7.4 7.4 10.0 10.0 8.3 5.5 8.9 8.8 9.2 7.5 8.5 7.7 6.1 7.8 3.7 6.2 2.7 2.9 2.0 2.9 2.5 3.4 3.4 3.2 3.3 2.8 3.5 3.5 8.6 9.6 9.5 16.0 18.3 1.9 4.4 6.7 7.4 10.6 5.7 4.1 3.8 2.8 4.5 1.8 2.1 4.2 17.7 2.6 0.0 3.4 61.5 2.1 9.6 5.3 3.6 12.0 30.8 3.1 1.6 8.4 1.1 1.9 14.7 72.0 6.8 4.1 7.1 3.3 30.8 4.7 2.0 9.8 5.8 45.1 10.5 9.7 1.8 18.7 10.3 5.4 17.5 32.6 18.8 3.3 7.6 8.6 3.7 6.6 2.6 4.1 6.0 6.4 6.6 7.0 9.8 9.9 10.9 3.6 1.8 2.6 15.0 8.9 5.0 3.4 PARP8 "ARTD16, FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846519 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.2" "Cell type enhanced" "Detected in many" "dendritic cells: 124.9;Excitatory neurons: 197.9;Inhibitory neurons: 139.3;Microglial cells: 112.4;Oligodendrocyte precursor cells: 158.3;T-cells: 157.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 91.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Midbody ring, Cytosol" "HPA049183: AB_2680667" "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favorable (1.12e-4)" 11.7 13.1 4.6 26.8 8.8 78.2 9.2 0.0 7.9 8.3 0.3 8.8 14.5 6.6 4.2 7.7 9.9 25.7 6.9 14.7 12.6 7.0 8.0 19.8 42.0 3.4 4.5 11.6 12.2 13.8 4.9 12.4 0.1 11.3 9.3 4.6 10.3 7.4 4.8 7.6 15.0 8.4 2.7 43.6 20.2 9.1 7.7 19.2 43.1 2.1 22.5 14.5 5.4 2.0 24.8 0.1 12.2 18.8 3.2 5.7 18.0 4.3 15.7 4.1 12.0 0.9 33.5 14.8 16.9 0.5 43.3 12.4 2.1 13.1 10.0 20.2 15.9 10.6 9.2 1.1 6.3 28.1 0.2 6.8 10.9 8.5 6.0 24.6 0.2 23.1 1.6 9.1 5.9 8.8 31.8 32.5 12.3 0.4 6.0 15.4 24.0 17.1 7.6 12.8 13.0 19.0 13.8 21.6 3.7 17.6 1.0 91.2 0.0 1.0 15.4 1.2 12.6 6.9 0.2 29.5 13.8 7.6 17.7 27.4 13.7 31.9 43.6 4.0 70.6 13.4 34.3 50.5 9.2 16.7 20.9 34.9 28.6 39.5 2.9 4.2 22.5 22.7 4.6 8.8 0.0 7.9 14.7 12.6 3.4 4.5 0.1 2.7 7.7 2.0 6.2 32.1 21.1 29.4 51.7 8.0 5.2 12.7 26.2 13.6 10.4 6.5 5.6 14.3 19.1 22.0 0.0 22.5 124.9 17.2 7.9 14.2 28.7 11.8 8.4 3.9 15.0 7.4 197.9 10.2 6.4 13.4 46.9 10.6 14.5 12.6 6.8 5.0 14.3 6.7 139.3 4.2 8.2 26.1 16.9 15.3 1.2 27.1 8.8 112.4 43.4 0.7 93.7 158.3 7.3 18.7 8.4 3.0 65.0 7.7 8.2 4.3 25.6 2.1 6.6 12.3 13.0 12.8 6.0 14.3 4.0 24.8 157.3 6.5 9.6 13.7 PARP9 "ARTD9, BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 95.8;BJ hTERT+ SV40 Large T+ RasG12V: 113.4;SK-MEL-30: 93.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" Mitochondria "HPA066708: AB_2685707" "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 20.1 29.4 14.0 35.8 15.1 20.8 17.6 13.8 17.4 20.3 14.8 22.5 21.2 19.6 19.1 24.8 20.1 28.8 18.3 13.5 15.1 22.0 68.3 36.5 30.5 21.3 15.5 12.9 22.0 23.7 18.5 20.1 16.8 18.9 19.5 5.8 39.9 12.6 13.6 11.6 21.4 29.1 17.6 44.3 20.0 6.4 17.4 30.6 16.8 17.3 25.9 26.0 16.5 16.1 23.1 7.7 2.8 1.9 16.9 34.6 2.6 7.6 41.0 95.8 113.4 12.0 24.9 5.2 16.4 15.3 60.2 24.8 6.6 13.4 19.9 40.3 4.5 24.9 7.6 6.4 18.0 8.1 15.9 28.4 12.9 13.6 3.4 19.1 20.8 15.7 2.3 20.7 3.9 10.2 26.0 10.1 1.1 4.7 21.1 27.3 27.2 1.7 37.0 13.1 1.7 6.6 20.2 3.3 93.8 1.5 10.7 9.0 12.6 4.1 11.8 0.9 4.7 12.8 7.1 9.5 14.1 8.7 7.7 41.9 29.9 36.9 19.8 41.1 18.5 15.9 20.6 22.3 27.5 11.4 15.6 19.3 87.5 30.2 45.2 3.3 24.9 23.3 14.0 15.1 13.8 17.4 13.5 15.1 21.3 15.5 16.8 17.6 17.4 16.1 37.0 41.7 44.2 13.4 18.9 7.1 10.8 13.8 12.5 0.8 10.5 6.3 5.8 10.0 35.1 20.2 0.0 5.2 14.0 32.5 1.9 30.4 1.6 23.6 28.1 37.4 10.7 19.0 0.3 39.9 19.3 19.9 22.4 23.2 10.1 19.5 21.8 50.1 42.0 0.0 1.3 11.5 10.2 32.3 9.2 4.5 18.3 41.2 7.2 45.0 50.2 12.1 32.0 17.1 3.9 36.8 11.7 24.0 13.6 8.9 17.5 19.3 48.8 1.0 19.7 18.9 16.3 0.9 1.9 15.7 6.7 1.6 23.5 17.0 8.6 14.4 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.6;Alveolar cells type 2: 60.6;Club cells: 39.0;Collecting duct cells: 57.0;Endometrial ciliated cells: 55.7;Glandular and luminal cells: 98.3;Pancreatic endocrine cells: 47.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 75.0" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 36.3;RPTEC TERT1: 30.3;RT4: 33.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 72.3" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: AB_2685663, HPA066960: AB_2685755, HPA069079: AB_2686079" "unprognostic (1.81e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (7.60e-2)" "unprognostic (1.88e-1)" "unprognostic (9.90e-2)" "unprognostic (3.39e-3)" "unprognostic (2.99e-2)" "prognostic favorable (1.47e-5)" "unprognostic (3.05e-3)" "unprognostic (6.72e-3)" "unprognostic (2.21e-2)" "unprognostic (2.43e-1)" 3.4 7.2 6.8 3.6 5.4 3.5 18.1 75.0 5.3 8.4 25.3 12.2 8.9 5.8 26.5 19.3 8.3 7.1 45.2 3.8 9.2 27.5 12.4 10.0 2.9 12.8 9.0 6.8 12.4 20.0 10.9 3.5 14.2 12.3 11.1 15.8 20.0 7.9 45.4 22.4 9.3 3.5 11.5 3.1 10.2 5.1 9.1 4.0 13.1 16.1 6.2 7.9 13.2 9.5 36.3 7.0 2.3 3.2 1.3 3.3 29.5 2.1 2.8 2.2 3.0 12.5 13.2 0.2 9.1 4.4 18.7 21.1 5.1 18.9 3.8 3.5 8.8 0.2 10.4 11.3 2.9 0.1 0.2 1.2 19.7 3.7 8.0 5.3 1.2 0.0 0.0 0.0 1.9 12.6 0.1 0.1 12.0 16.4 1.9 0.1 2.8 5.2 30.3 33.4 6.1 2.0 8.8 29.4 7.7 23.7 23.7 0.3 0.3 1.8 4.3 0.2 4.2 1.4 2.7 4.8 1.7 0.0 0.5 0.4 0.0 7.2 1.2 0.1 2.3 1.2 2.0 1.7 0.0 1.1 2.6 1.7 0.6 2.6 0.1 0.2 1.9 0.6 6.8 5.4 75.0 5.3 3.8 9.2 12.8 9.0 14.2 11.5 9.1 9.5 6.4 86.6 60.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 35.0 29.8 0.0 0.0 39.0 57.0 0.0 4.3 3.8 0.0 5.9 37.6 0.0 55.7 8.6 1.6 0.0 0.0 0.0 26.4 0.7 5.5 0.0 98.3 1.3 14.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 2.7 0.0 0.0 35.7 27.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 26.4 10.3 1.7 0.0 0.0 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PBDC1 "CXorf26, MGC874" ENSG00000102390 "Polysaccharide biosynthesis domain containing 1" Q9BVG4 X 76173040-76178314 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003155 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Nucleoli, Cytosol" "HPA003155: AB_1078592" "unprognostic (6.95e-2)" "unprognostic (9.85e-2)" "unprognostic (1.02e-2)" "unprognostic (3.78e-2)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (2.47e-3)" "unprognostic (7.23e-2)" "unprognostic (1.78e-1)" "unprognostic (1.56e-3)" "unprognostic (8.82e-3)" "unprognostic (3.64e-1)" "unprognostic (1.39e-2)" "unprognostic (1.05e-1)" "unprognostic (4.98e-2)" "prognostic favorable (8.57e-4)" "unprognostic (1.62e-1)" 24.2 31.0 12.4 22.6 11.8 46.6 23.1 12.7 19.9 22.6 12.9 27.2 40.3 24.0 23.6 33.3 19.3 19.2 21.1 12.1 13.5 29.4 31.8 22.4 26.3 13.3 14.0 20.2 19.5 20.8 19.8 22.8 13.1 25.2 28.2 20.1 21.4 18.9 24.3 26.4 33.2 26.1 12.6 25.6 23.8 6.5 13.7 20.6 19.0 19.3 26.7 33.1 21.9 12.5 35.3 50.9 41.5 28.2 53.5 52.3 36.0 62.5 51.2 53.9 46.3 48.9 46.8 47.1 40.3 62.3 68.6 49.7 70.3 68.1 69.5 36.1 45.2 36.0 30.1 72.4 82.0 104.6 49.2 42.2 55.4 74.9 63.2 33.3 69.6 17.0 50.7 22.9 67.8 41.6 49.1 75.3 116.1 87.0 78.9 41.3 43.7 6.0 79.8 64.9 24.3 30.9 27.6 44.0 0.2 53.0 26.8 39.1 60.8 39.9 40.8 48.6 56.7 40.6 77.3 27.8 44.7 35.7 32.3 17.6 41.1 42.6 68.3 62.8 50.6 70.7 61.0 67.8 53.5 57.3 61.9 59.4 7.7 69.6 71.8 56.0 57.0 44.0 12.4 11.8 12.7 19.9 12.1 13.5 13.3 14.0 13.1 12.6 13.7 12.5 32.8 35.3 29.1 2.6 32.9 52.9 84.4 119.6 50.7 21.0 29.3 35.3 38.5 31.5 64.3 40.5 14.6 55.5 57.5 46.9 49.0 71.0 0.9 51.9 49.1 34.4 27.6 17.5 2.3 62.5 60.4 42.9 28.1 45.7 51.4 33.5 25.7 47.9 69.8 8.4 2.4 50.3 77.3 30.5 31.5 3.8 47.8 38.1 46.2 1.9 68.0 26.4 45.3 2.5 2.8 58.7 44.7 38.7 25.7 58.3 105.5 84.1 49.1 25.0 52.6 35.9 47.0 4.4 18.9 59.4 70.5 55.0 49.2 82.0 51.9 82.1 PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 382.3;Excitatory neurons: 475.9;Inhibitory neurons: 405.0;Oligodendrocyte precursor cells: 327.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 93.0;NTERA-2: 111.5;SK-BR-3: 186.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" 24.3 32.1 16.5 11.8 22.3 3.1 36.1 10.7 18.0 88.3 1.9 52.3 22.4 136.8 21.6 30.1 74.6 37.6 24.0 15.3 14.1 29.4 7.7 20.7 4.5 8.8 32.7 52.1 48.1 29.5 14.3 19.5 6.7 38.0 19.8 17.1 43.8 53.8 36.3 10.2 19.9 125.2 13.7 10.2 21.9 6.8 12.6 10.9 35.1 26.5 8.1 40.2 41.5 12.1 2.9 74.4 82.4 19.1 50.8 23.3 3.4 25.2 20.9 8.4 6.1 14.2 11.8 0.0 5.5 47.8 4.3 22.8 31.7 8.1 3.6 3.1 31.3 93.0 56.5 0.3 34.7 0.0 22.2 24.4 0.0 5.4 2.1 19.2 0.3 0.0 0.2 0.0 2.2 47.1 0.2 0.6 111.5 3.8 4.5 0.0 21.6 27.0 6.3 44.1 2.5 39.6 27.8 186.1 0.1 71.4 73.2 0.0 0.5 3.7 8.6 24.2 8.1 8.5 61.2 0.1 0.4 0.2 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 16.5 22.3 10.7 18.0 15.3 14.1 8.8 32.7 6.7 13.7 12.6 12.1 28.6 22.4 18.6 382.3 2.8 22.8 115.0 39.8 70.6 39.9 129.9 87.8 50.0 98.7 25.3 33.1 110.5 101.3 1.5 29.2 33.2 47.9 91.3 47.7 144.3 47.0 90.9 30.3 475.9 68.7 7.3 126.7 32.1 38.5 71.7 57.6 68.9 18.7 9.7 5.0 405.0 38.2 50.8 1.9 17.5 124.4 63.6 12.1 16.0 125.5 1.6 33.5 1.0 327.2 227.4 31.7 72.5 103.8 2.8 41.5 40.4 57.9 37.3 30.6 39.5 142.0 70.9 2.3 17.5 83.6 28.1 104.7 7.6 168.0 43.7 75.9 PBX3 ENSG00000167081 "PBX homeobox 3" P40426 9 125747345-125967377 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 153.1" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 192.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 13.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 13.9" "Cell line enhanced" "Detected in many" "THP-1: 90.1" "Region enhanced" "Detected in all" "olfactory bulb: 167.4" "Group enriched" "Detected in all" 5 "basal ganglia: 46.3;olfactory bulb: 161.9" HPA003881 Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA003881: AB_1855020" "unprognostic (1.97e-2)" "unprognostic (3.78e-2)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (2.20e-1)" "unprognostic (3.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.88e-1)" "unprognostic (2.42e-3)" "unprognostic (7.02e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (8.03e-2)" "unprognostic (6.29e-2)" 10.9 56.0 10.4 12.9 14.6 6.9 10.0 17.4 13.2 27.2 7.0 47.9 6.8 9.8 20.0 11.8 14.2 22.5 38.0 7.2 15.0 7.1 18.1 13.0 8.0 19.7 21.0 58.2 18.8 153.1 12.6 6.7 19.4 30.9 13.7 28.0 11.8 28.0 8.5 19.4 14.3 22.6 18.8 12.8 21.5 8.2 15.3 16.7 35.1 5.7 6.9 20.7 21.9 21.7 11.6 11.0 50.0 43.1 13.1 19.1 8.5 29.9 16.8 19.2 14.5 14.3 21.1 11.3 3.6 22.1 20.8 8.5 28.3 12.3 38.3 12.4 20.5 9.7 7.9 5.8 17.2 9.6 15.5 9.5 13.7 14.5 10.0 45.3 23.1 7.2 0.4 10.3 43.5 5.9 10.0 4.9 35.8 14.2 7.4 18.9 73.3 1.5 15.6 6.4 25.9 45.1 20.2 3.8 9.4 18.8 15.7 90.1 26.6 40.0 10.2 23.8 57.1 7.2 12.8 11.5 19.7 15.2 20.6 2.3 1.7 2.2 0.8 1.4 0.9 1.0 0.9 0.7 1.9 1.5 1.7 0.7 1.4 3.2 1.3 13.9 0.8 1.0 10.4 14.6 17.4 13.2 7.2 15.0 19.7 21.0 19.4 18.8 15.3 21.7 7.3 9.6 16.7 17.9 10.0 22.7 10.3 3.0 6.8 7.5 11.5 8.3 60.3 2.8 8.6 12.9 37.5 0.6 20.7 1.3 7.9 13.5 15.2 1.1 14.0 11.9 11.5 6.3 44.3 2.5 0.9 23.4 5.6 1.5 16.5 9.4 9.7 12.6 15.3 42.1 19.3 5.7 6.1 29.0 23.7 11.4 19.9 22.9 7.2 91.8 13.6 11.5 6.2 136.2 192.2 3.1 12.1 11.3 3.8 13.0 0.9 2.8 8.5 43.1 0.0 5.3 13.0 33.7 16.0 10.4 26.3 0.4 10.5 8.7 3.4 8.7 PCBP3 "FLJ44028, PCBP3-OT1, PCBP3OT" ENSG00000183570 "Poly(rC) binding protein 3" P57721 21 45643694-45942454 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.6;retina: 81.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 159.4;Cone photoreceptor cells: 50.1;Horizontal cells: 116.1;Late spermatids: 79.8;Muller glia cells: 49.3;Rod photoreceptor cells: 83.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.0;HDLM-2: 56.9;HSkMC: 40.8;SH-SY5Y: 46.9;U-87 MG: 25.0;U-937: 31.3" "Region enriched" "Detected in all" 5 "olfactory bulb: 229.1" "HPA030247, HPA073145" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" Vesicles "HPA030247: AB_10601244, HPA073145: " "unprognostic (3.88e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-4)" "unprognostic (9.89e-4)" "unprognostic (2.74e-1)" "unprognostic (1.40e-1)" "unprognostic (4.10e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-2)" "unprognostic (1.64e-3)" "unprognostic (1.12e-3)" "unprognostic (1.97e-2)" "unprognostic (1.96e-6)" "unprognostic (8.67e-2)" "unprognostic (2.32e-2)" "unprognostic (8.04e-2)" "unprognostic (1.97e-2)" 7.3 7.1 8.9 7.5 6.8 8.9 4.5 34.6 11.9 8.2 2.8 13.7 1.7 8.7 7.5 1.4 5.3 2.6 3.4 13.5 8.1 4.8 1.3 2.8 3.3 32.3 12.0 3.9 2.7 0.1 22.6 1.2 31.3 2.3 1.6 81.5 1.8 0.8 0.4 2.1 8.7 7.8 8.9 10.0 4.7 14.8 17.9 18.9 1.0 1.7 2.9 4.1 2.8 9.5 0.0 0.0 0.5 0.0 13.7 29.0 0.2 1.8 0.4 3.1 1.4 0.0 0.0 0.0 0.7 8.2 3.9 0.1 1.7 0.0 0.5 56.9 0.2 0.0 0.0 0.0 13.7 0.0 0.0 40.8 0.2 0.5 0.8 0.0 0.0 2.0 0.0 0.2 1.8 0.7 16.5 3.3 0.8 0.1 2.8 0.0 0.1 2.4 0.0 0.0 4.9 46.9 1.2 0.0 0.0 1.3 0.0 8.7 0.0 0.0 0.1 12.3 0.0 0.7 3.1 0.0 25.0 31.3 1.1 2.1 0.2 3.0 0.7 0.1 0.1 1.3 0.4 0.0 0.0 1.4 0.7 0.1 0.7 0.3 0.1 0.0 0.4 0.2 8.9 6.8 34.6 11.9 13.5 8.1 32.3 12.0 31.3 8.9 17.9 9.5 0.6 0.0 0.0 2.3 6.2 0.3 0.1 0.3 0.0 159.4 0.1 0.5 3.6 0.0 0.7 1.8 50.1 0.1 0.3 0.0 0.0 0.1 36.5 0.2 8.9 2.2 3.0 0.0 3.8 0.2 0.1 2.3 0.5 0.3 0.0 0.2 2.2 0.0 0.4 116.1 4.6 0.1 0.0 0.0 0.7 79.8 8.4 0.9 3.6 1.0 0.0 49.3 0.0 0.5 5.5 0.9 0.1 12.8 4.1 1.3 0.0 0.4 0.0 83.1 0.0 1.1 3.9 34.1 21.2 0.0 0.0 0.0 2.5 0.2 0.2 0.5 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.4;placenta: 25.9;prostate: 10.6;seminal vesicle: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Endometrial ciliated cells: 26.5;Excitatory neurons: 64.9;Glandular and luminal cells: 29.1;Inhibitory neurons: 57.7;Oligodendrocyte precursor cells: 46.8;Oligodendrocytes: 59.6" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.5;HUVEC TERT2: 27.4;MOLT-4: 24.1;TIME: 55.4;U-138 MG: 14.5;U-251 MG: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 88000 "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: AB_1855041, HPA073462: AB_2686605" "unprognostic (7.20e-2)" "unprognostic (8.74e-3)" "unprognostic (4.30e-2)" "unprognostic (8.12e-5)" "unprognostic (8.33e-2)" "unprognostic (3.20e-1)" "unprognostic (5.27e-3)" "unprognostic (4.51e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-3)" "unprognostic (8.72e-2)" "unprognostic (1.45e-1)" "unprognostic (8.68e-4)" "unprognostic (8.88e-2)" "unprognostic (6.31e-2)" "unprognostic (2.16e-4)" 0.5 5.1 20.5 0.2 35.4 0.0 0.1 0.9 23.9 1.5 0.0 0.5 0.1 1.6 0.5 0.3 1.2 0.5 1.2 19.6 15.2 2.1 0.1 0.7 0.0 7.7 24.9 2.3 0.2 0.0 1.4 25.9 11.3 10.6 0.2 3.0 0.5 17.3 0.0 0.0 0.4 0.7 3.7 0.0 0.4 1.4 16.8 0.1 0.5 0.0 0.0 1.8 2.8 19.1 0.0 0.7 8.7 0.0 0.3 0.0 0.0 8.6 4.6 0.7 0.4 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.9 0.0 4.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 11.5 27.4 0.0 0.3 0.0 4.2 0.0 24.1 0.0 0.0 0.0 0.3 0.5 0.3 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.3 55.4 14.5 0.0 0.1 12.9 0.0 0.0 0.0 1.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 35.4 0.9 23.9 19.6 15.2 7.7 24.9 11.3 3.7 16.8 19.1 1.4 0.0 0.6 58.1 0.0 0.1 0.5 0.1 1.2 15.0 1.2 2.7 2.3 0.0 0.7 0.0 0.0 0.8 0.0 0.9 1.9 0.0 5.6 26.5 4.6 4.0 0.0 0.0 64.9 0.0 0.9 15.5 0.0 29.1 0.0 5.0 0.0 0.0 1.8 0.0 57.7 0.2 0.0 0.0 0.0 1.7 0.0 0.5 0.0 6.5 0.0 8.6 0.0 46.8 59.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.1 2.7 0.0 4.3 11.5 17.4 0.9 0.0 0.3 2.9 0.2 3.9 0.1 0.4 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;parathyroid gland: 2.7;retina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;AN3-CA: 10.7;EFO-21: 7.6;MCF7: 4.4;T-47d: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" 0.2 0.3 1.5 0.1 1.3 0.0 0.2 4.2 2.2 0.8 0.0 0.1 0.0 0.5 0.1 0.0 0.2 0.8 0.0 1.1 0.3 0.7 0.1 0.4 0.1 0.0 1.5 0.0 1.8 2.7 1.0 0.0 0.3 0.1 0.0 2.4 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 2.1 4.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.6 0.0 0.8 0.0 0.1 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.3 0.0 1.0 0.0 0.1 0.0 4.4 0.0 0.0 3.5 0.8 2.8 0.0 0.0 0.0 0.4 1.6 0.2 1.9 0.0 1.9 0.4 1.9 6.5 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 4.2 2.2 1.1 0.3 0.0 1.5 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA4 "CNR1, CNRN1, CRNR1, PCDH-ALPHA4" ENSG00000204967 "Protocadherin alpha 4" Q9UN74 5 140806929-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.0;granulocytes: 3.8;Respiratory ciliated cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.6;AF22: 5.6;EFO-21: 5.1;T-47d: 5.4" "Not detected" "Not detected" "HPA043180, HPA073478" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Brain - Smell perception" "Cluster 38: EFO-21 - Unknown function" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA043180: AB_10806381, HPA073478: AB_2686608" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (2.85e-1)" "unprognostic (5.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.14e-2)" "unprognostic (2.56e-1)" "unprognostic (7.90e-3)" "unprognostic (7.14e-3)" "unprognostic (7.00e-2)" "unprognostic (5.06e-3)" "unprognostic (6.94e-5)" "unprognostic (5.01e-3)" "unprognostic (6.21e-2)" "unprognostic (3.98e-1)" "unprognostic (6.29e-3)" "unprognostic (4.79e-2)" 0.2 0.2 0.9 0.2 1.2 0.9 0.4 2.9 1.1 0.5 0.0 0.3 0.3 0.6 0.4 0.1 0.3 1.3 0.1 0.9 0.5 0.4 0.1 0.4 0.3 0.6 0.5 0.2 1.2 0.1 0.4 0.1 0.6 0.4 0.2 0.9 0.2 0.3 0.3 0.5 0.2 0.3 0.3 0.3 0.3 0.4 0.4 0.1 0.3 0.1 0.2 0.2 0.1 1.5 0.1 6.6 5.6 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 1.1 0.1 5.1 0.1 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.2 0.1 0.2 0.3 0.3 1.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.1 0.1 0.1 0.2 1.7 1.2 0.9 0.1 0.1 0.2 0.1 0.2 0.2 2.3 0.0 1.4 0.5 0.8 5.4 0.1 0.6 1.2 0.8 0.5 0.1 0.3 0.1 0.1 0.2 0.2 0.5 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.9 1.2 2.9 1.1 0.9 0.5 0.6 0.5 0.6 0.3 0.4 1.5 0.1 3.2 2.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.2 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.3 0.6 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 3.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.2 2.9 1.1 0.0 0.4 0.5 1.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.4 PCDHA5 "CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5" ENSG00000204965 "Protocadherin alpha 5" Q9Y5H7 5 140821604-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.3" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 6.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.3;EFO-21: 3.4;T-47d: 3.7;WM-115: 1.3" "Low region specificity" "Detected in many" HPA044557 Approved Approved "Nuclear speckles,Plasma membrane,Mitochondria" NA NA "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles, Mitochondria" "HPA044557: AB_10970597" "unprognostic (4.95e-2)" "unprognostic (6.23e-2)" "unprognostic (2.06e-1)" "unprognostic (8.81e-4)" "unprognostic (5.10e-2)" "unprognostic (6.25e-3)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (2.46e-2)" "unprognostic (4.49e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-4)" "unprognostic (9.30e-4)" "unprognostic (1.07e-1)" "unprognostic (1.39e-1)" "unprognostic (8.17e-5)" "unprognostic (2.11e-1)" 0.1 0.1 0.6 0.0 1.0 0.0 0.1 3.3 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.0 3.3 1.1 0.9 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHAC1 ENSG00000248383 "Protocadherin alpha subfamily C, 1" Q9H158 5 140926299-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "parathyroid gland: 29.8" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.7;EFO-21: 2.5;hTCEpi: 5.9;PC-3: 4.2;SCLC-21H: 2.9" "Low region specificity" "Detected in all" HPA052775 Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" Vesicles "HPA052775: AB_2681942" "unprognostic (2.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.32e-3)" "unprognostic (9.52e-3)" "unprognostic (1.36e-1)" "unprognostic (9.63e-2)" "unprognostic (4.27e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" "unprognostic (3.64e-3)" "unprognostic (1.04e-3)" "unprognostic (3.25e-3)" "unprognostic (1.35e-1)" "unprognostic (2.96e-1)" "unprognostic (3.29e-2)" 0.4 0.4 0.6 0.5 0.7 0.0 0.1 4.5 1.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.0 0.0 0.5 0.5 0.2 0.1 0.7 1.2 2.0 3.1 0.0 1.2 29.8 0.7 0.0 2.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.7 0.7 0.0 0.9 0.0 0.6 0.0 0.0 0.6 0.0 5.7 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.7 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 4.2 0.0 0.0 0.0 0.1 0.3 2.9 1.7 0.0 0.4 0.0 0.5 0.3 0.0 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 4.5 1.0 0.5 0.5 2.0 3.1 2.3 0.0 0.7 0.6 0.1 6.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 1.2 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 9.7;Endometrial stromal cells: 8.2;Fibroblasts: 9.5;Horizontal cells: 8.4;Peritubular cells: 6.4;Skeletal myocytes: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.7;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" 3.2 2.1 2.7 0.7 3.0 0.0 3.4 3.3 3.7 3.6 0.3 2.0 0.6 5.4 3.8 1.5 4.0 2.4 2.3 3.2 4.2 1.5 0.3 2.1 0.4 5.0 3.7 4.2 8.5 1.4 2.7 0.1 5.7 2.4 0.9 1.6 2.1 1.9 1.6 1.3 0.9 3.3 5.0 0.7 1.3 0.5 2.7 0.4 1.5 2.1 0.2 2.1 2.1 6.7 0.0 0.0 0.3 1.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.7 5.8 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 3.0 3.3 3.7 3.2 4.2 5.0 3.7 5.7 5.0 2.7 6.7 9.7 0.0 0.5 0.0 0.0 1.1 0.4 0.2 0.6 4.9 2.6 3.8 1.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.4 8.2 4.3 0.0 0.0 0.0 1.7 0.0 9.5 0.0 0.3 0.0 0.1 3.6 0.0 0.1 8.4 0.0 0.0 2.0 0.0 1.1 0.0 1.5 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 0.6 0.0 6.4 0.0 0.7 0.0 0.0 2.5 0.6 0.0 8.7 4.0 1.4 0.5 0.0 2.0 0.0 0.0 0.5 0.0 0.4 PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330571-141512981 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 2.4;Cardiomyocytes: 1.8;Horizontal cells: 3.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 4.5;T-47d: 7.3;WM-115: 3.3" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 37: Myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA036547: AB_10669798" "unprognostic (9.50e-4)" "unprognostic (2.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.42e-3)" "unprognostic (3.39e-1)" "unprognostic (3.97e-2)" "unprognostic (2.42e-1)" "unprognostic (5.61e-3)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-3)" "unprognostic (4.76e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-3)" 0.3 0.2 1.1 0.2 2.3 0.2 0.2 3.2 2.0 0.5 0.0 0.5 0.2 0.6 0.9 0.2 0.4 0.1 1.2 2.2 0.9 0.2 0.1 0.3 0.1 1.5 1.4 0.6 0.5 0.5 0.9 0.5 0.9 0.3 0.2 1.0 0.2 0.2 0.7 0.3 0.1 0.4 1.7 0.2 0.1 0.7 1.4 0.1 0.2 0.4 0.1 0.4 0.3 1.3 0.0 0.2 0.3 1.1 0.7 1.3 0.1 1.1 0.7 0.3 0.6 0.3 0.1 0.2 1.8 0.7 0.5 0.1 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.1 1.1 0.3 0.0 0.4 2.1 0.0 0.1 0.1 0.5 4.5 0.0 0.1 0.5 0.1 0.0 0.2 2.0 1.6 0.2 0.2 0.2 1.0 1.3 0.1 0.6 1.1 0.3 7.3 0.2 0.5 2.0 0.3 1.0 0.2 0.1 0.6 0.1 2.4 0.1 3.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.1 2.3 3.2 2.0 2.2 0.9 1.5 1.4 0.9 1.7 1.4 1.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.7;Cone photoreceptor cells: 16.7;Horizontal cells: 23.5;Skeletal myocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.6;HSkMC: 16.1;T-47d: 19.7;U-2197: 11.6" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" 1.6 1.6 3.5 0.4 3.2 0.1 1.1 4.1 2.4 1.3 0.8 1.0 0.8 1.3 0.7 1.7 1.3 1.4 1.0 2.7 3.8 0.5 1.5 1.3 0.4 3.3 3.1 1.3 0.6 2.1 0.8 3.6 3.4 1.4 0.9 2.5 1.8 1.8 1.1 2.0 1.0 1.1 4.2 0.9 2.0 0.5 3.9 0.4 2.1 0.3 0.5 0.8 1.3 3.8 0.0 0.0 14.6 7.5 6.3 2.7 6.9 2.6 0.1 3.6 5.6 0.3 0.9 0.8 9.6 3.7 0.2 0.4 3.5 2.4 2.8 0.9 0.1 0.0 0.3 0.0 2.5 1.5 0.3 16.1 0.4 2.4 1.0 0.4 1.4 0.3 0.0 0.1 9.0 0.1 0.1 0.4 1.4 0.0 0.1 0.2 1.2 0.0 2.4 0.1 2.0 0.7 0.4 0.1 0.4 3.5 19.7 1.9 3.3 6.7 0.4 11.6 0.1 0.2 1.2 0.1 3.4 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 3.2 4.1 2.4 2.7 3.8 3.3 3.1 3.4 4.2 3.9 3.8 5.8 0.0 2.0 0.0 0.9 0.1 2.3 0.6 1.2 27.7 2.2 2.2 3.4 1.5 1.6 1.8 16.7 2.1 1.3 0.7 0.0 1.0 0.0 1.3 7.7 4.8 1.2 0.4 0.0 1.4 1.3 4.8 1.5 2.0 1.3 1.0 4.6 1.7 1.0 23.5 0.0 1.6 0.0 0.0 0.0 0.2 3.4 0.7 1.8 0.0 0.0 5.7 0.0 0.0 0.0 3.1 0.4 2.2 0.5 2.8 0.4 0.5 0.0 6.7 6.6 14.9 3.7 0.4 0.7 1.2 0.4 0.4 0.5 3.0 1.3 1.5 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.6;Endometrial stromal cells: 1.9;Fibroblasts: 1.3;Horizontal cells: 3.3;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 7.1;BJ: 2.3;EFO-21: 5.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" 1.2 1.2 2.6 0.2 1.7 0.0 0.9 2.2 2.6 1.6 0.1 0.7 0.0 1.4 0.9 0.2 1.2 0.9 3.7 2.5 1.8 0.5 0.6 0.9 0.0 3.8 2.9 2.5 0.9 0.6 1.2 1.7 2.2 0.7 0.2 1.8 0.7 0.8 0.8 0.5 0.2 0.9 3.4 0.2 0.4 1.5 2.9 0.2 0.8 0.9 0.1 0.8 0.9 2.5 0.0 0.0 7.1 0.0 0.0 0.9 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 2.2 2.6 2.5 1.8 3.8 2.9 2.2 3.4 2.9 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.9 0.1 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Skeletal myocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;BJ: 4.3;HSkMC: 4.3;HUVEC TERT2: 4.3;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" 1.7 1.3 1.6 0.4 1.8 0.0 0.9 3.7 1.7 1.3 0.0 0.9 0.2 1.6 0.8 0.4 0.9 0.8 1.5 2.9 1.5 0.4 0.3 1.0 0.1 2.1 2.4 1.6 2.1 2.3 1.0 0.8 1.7 1.1 0.3 1.5 0.8 1.1 0.7 0.5 0.3 1.5 2.0 0.3 0.4 0.7 2.1 0.2 0.7 1.0 0.1 0.7 0.8 2.5 0.0 0.1 0.8 0.4 3.3 7.4 0.0 4.3 3.4 0.2 0.8 0.0 0.1 0.7 1.4 3.7 1.3 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.3 4.3 0.1 0.0 0.0 2.6 4.3 0.0 0.1 0.2 1.8 0.6 0.2 0.2 0.1 0.0 0.2 0.3 1.2 0.1 0.2 0.0 0.6 1.3 0.2 0.2 0.9 0.3 1.6 0.0 2.8 1.8 0.5 2.4 0.3 0.1 0.2 0.1 6.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 3.7 1.7 2.9 1.5 2.1 2.4 1.7 2.0 2.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.6;Cardiomyocytes: 5.0;Endometrial stromal cells: 4.6;Hepatic stellate cells: 3.6;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.6;T-47d: 5.6;WM-115: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" 1.4 1.1 1.6 0.7 1.8 0.1 1.3 7.2 1.6 2.7 0.0 2.0 0.2 3.2 1.4 0.8 2.0 1.1 2.7 1.7 1.8 0.8 0.5 1.5 0.4 1.8 1.7 3.5 1.2 1.1 1.8 2.3 0.9 1.2 0.4 2.0 1.5 1.6 0.9 1.5 0.8 2.0 0.8 0.9 0.7 0.8 2.0 0.5 1.2 1.0 0.4 1.6 1.5 1.9 0.0 0.3 2.7 0.4 1.3 4.7 0.1 2.1 0.7 1.1 1.1 0.0 0.1 2.0 2.6 3.3 1.0 0.4 0.1 0.4 0.7 0.0 0.2 0.0 0.3 0.2 0.7 0.1 0.1 4.9 0.3 0.2 0.1 1.0 1.6 0.1 0.2 1.1 0.3 0.4 0.7 1.7 0.3 0.0 0.1 1.4 0.4 0.0 0.3 0.1 9.6 0.7 0.1 0.3 0.6 0.6 5.6 0.1 4.8 0.7 0.3 0.7 0.7 0.4 1.7 0.4 0.8 0.7 12.2 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 1.6 1.8 7.2 1.6 1.7 1.8 1.8 1.7 0.9 0.8 2.0 1.9 2.8 0.0 2.2 0.0 0.4 0.0 0.8 0.0 0.0 10.6 0.3 1.0 5.0 1.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.5 0.4 4.6 1.8 0.0 0.4 0.0 1.5 0.1 2.2 0.0 0.4 0.0 0.6 3.6 0.7 0.1 1.7 0.0 0.2 0.0 0.3 0.0 0.3 1.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.1 2.2 1.6 0.4 0.0 0.3 0.7 0.9 0.0 5.2 1.9 0.3 0.3 0.5 0.0 0.3 0.2 0.5 0.2 0.2 PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.3;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.2;Skeletal myocytes: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.3;BJ hTERT+: 20.8;hTERT-RPE1: 10.9;SH-SY5Y: 18.6;T-47d: 8.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" 0.5 0.4 1.0 0.2 0.9 0.0 0.6 5.9 1.0 1.2 0.0 1.1 0.1 1.3 1.1 0.5 1.0 0.4 1.5 1.1 0.6 0.6 0.4 0.7 0.1 1.5 1.2 1.5 0.7 2.2 0.8 1.3 0.9 0.9 0.3 1.6 0.8 0.8 0.7 1.0 0.4 0.8 1.0 0.4 0.3 0.5 1.3 0.2 1.9 0.5 0.1 0.9 0.7 1.5 0.0 1.6 2.3 0.0 6.6 11.3 0.0 3.3 20.8 4.2 6.1 0.0 0.0 0.5 5.2 0.7 0.2 0.2 0.0 0.1 3.4 0.0 0.3 0.0 0.4 0.2 1.1 0.0 0.0 5.0 0.1 0.0 0.7 10.9 1.7 0.0 0.0 0.1 0.1 0.1 0.6 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.4 18.6 0.0 0.1 0.1 3.7 8.1 0.0 6.7 0.1 0.1 3.1 0.1 0.1 1.9 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.9 1.0 1.1 0.6 1.5 1.2 0.9 1.0 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.3 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.6 0.0 2.8 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.3 PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.4;Cardiomyocytes: 3.5;Horizontal cells: 3.3;Skeletal myocytes: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" 0.1 0.1 0.6 0.1 0.6 0.4 0.1 3.9 0.8 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.8 0.5 0.0 0.1 0.1 0.1 1.1 0.7 0.3 0.1 0.0 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.3 0.3 0.1 0.1 0.3 0.1 0.1 0.1 0.9 0.1 0.4 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.2 0.6 0.1 0.6 0.4 0.4 0.1 0.0 0.1 0.3 0.2 0.4 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.2 0.4 0.6 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.6 0.6 3.9 0.8 0.8 0.5 1.1 0.7 0.7 0.3 0.9 1.2 1.2 0.0 0.6 0.0 0.1 0.0 0.9 0.0 0.0 11.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.1 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.3 0.4 0.7 0.1 3.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.1 0.1 1.5 0.0 0.7 0.0 0.2 0.0 1.7 0.0 5.2 0.9 0.7 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.5 PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402932-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cardiomyocytes: 1.3;Endometrial stromal cells: 1.5;Horizontal cells: 3.3;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.6;HSkMC: 4.0;hTERT-RPE1: 16.9;TIME: 4.6;U-87 MG: 5.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" 1.8 1.6 3.3 0.7 3.5 0.1 1.3 6.6 3.2 2.0 0.4 1.2 0.5 2.5 1.1 1.4 1.9 2.0 1.1 3.7 2.6 0.8 0.4 1.5 0.5 3.6 3.4 2.8 0.8 1.1 0.9 1.0 3.8 1.5 0.7 4.4 1.1 2.2 0.8 1.7 0.6 1.8 3.7 1.1 0.8 0.4 3.6 0.5 1.4 1.2 0.7 1.2 1.4 5.7 0.0 0.1 0.6 1.6 0.1 0.2 0.2 0.7 0.0 0.6 0.6 0.2 0.4 1.3 3.6 2.0 0.3 0.1 0.1 0.2 0.7 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.2 4.0 0.1 0.4 0.3 16.9 1.0 0.0 0.1 0.2 0.3 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.4 1.1 0.4 0.1 0.5 0.4 0.9 0.4 4.6 0.3 0.3 0.1 2.5 0.2 0.0 0.0 5.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.5 6.6 3.2 3.7 2.6 3.6 3.4 3.8 3.7 3.6 5.7 0.6 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.6 4.5 0.2 0.3 1.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.4 0.2 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.3 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.4;ASC TERT1: 8.4;fHDF/TERT166: 3.5;TIME: 5.5" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" 0.7 0.3 0.4 0.2 0.8 0.0 0.5 3.8 0.8 0.8 0.0 0.8 0.0 1.0 0.6 0.3 0.7 0.4 1.2 0.9 0.5 0.3 0.2 0.5 0.2 1.3 1.4 1.2 0.7 1.1 0.7 0.4 0.6 0.4 0.3 0.8 0.8 0.4 0.5 0.6 0.3 0.7 0.6 0.4 0.4 0.4 0.8 0.3 0.6 0.5 0.2 0.6 0.6 1.4 0.0 0.6 0.4 0.3 10.4 8.4 0.2 1.2 2.0 0.7 0.8 0.0 0.0 1.8 0.3 3.5 0.6 0.5 0.0 0.2 0.5 0.0 0.2 0.0 0.2 0.1 0.4 0.1 0.0 2.1 0.4 0.2 0.1 0.2 1.0 0.0 0.2 0.8 0.2 0.4 0.6 0.9 0.1 0.0 0.1 1.5 0.6 0.0 0.2 0.1 2.4 0.5 0.0 0.0 0.2 0.3 0.6 0.0 5.5 0.5 0.1 0.5 0.6 0.2 1.8 0.2 0.4 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 3.8 0.8 0.9 0.5 1.3 1.4 0.6 0.6 0.8 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.3;SuSa: 15.5;TIME: 22.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" 1.3 1.1 1.3 0.4 1.5 0.0 0.9 4.4 1.4 1.5 1.8 1.1 0.2 1.6 1.5 0.7 1.3 0.5 1.5 2.0 3.2 1.4 1.6 1.1 0.1 2.0 2.0 2.4 1.0 1.9 1.2 3.0 1.5 1.2 0.4 1.4 1.6 1.4 1.0 1.7 0.5 1.0 1.4 0.4 0.4 0.5 2.5 0.7 1.7 0.8 0.2 1.0 1.1 1.5 0.0 1.1 11.1 0.1 6.9 8.5 1.3 10.8 43.3 4.4 3.0 0.0 0.0 0.4 8.3 0.3 0.2 3.3 0.0 0.0 4.6 0.0 0.0 0.0 0.2 2.4 2.8 0.0 0.0 8.4 0.1 4.1 0.0 0.1 6.7 0.0 0.4 0.1 0.0 0.0 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 15.5 5.6 4.2 22.7 6.0 1.8 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 1.5 4.4 1.4 2.0 3.2 2.0 2.0 1.5 1.4 2.5 1.5 0.2 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.3;ASC TERT1: 49.6;BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" 2.8 2.7 3.6 1.1 3.6 0.0 1.8 5.8 3.1 2.0 3.3 1.7 0.7 3.1 2.0 1.9 2.8 1.6 2.9 3.9 6.4 2.2 2.1 2.7 0.4 5.1 4.7 5.7 3.8 20.3 1.7 4.8 5.4 3.0 0.9 3.1 4.7 3.9 2.1 3.8 0.8 2.8 5.3 1.3 1.5 1.9 4.9 1.3 4.5 1.9 0.8 1.9 2.1 6.1 0.0 2.4 0.3 0.0 66.3 49.6 1.3 18.3 0.0 29.2 32.5 2.9 10.0 10.6 23.4 20.5 0.0 13.9 0.0 7.6 16.4 0.0 3.1 0.0 0.0 0.1 6.9 0.0 6.5 17.6 1.5 1.7 9.4 12.6 9.0 0.0 0.2 0.0 1.0 8.1 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.0 0.1 0.0 0.1 0.0 2.0 19.1 0.1 9.2 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.6 5.8 3.1 3.9 6.4 5.1 4.7 5.4 5.3 4.9 6.1 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.2 1.5 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.8 0.5 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.9;Cone photoreceptor cells: 6.2;Horizontal cells: 10.1;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.0;EFO-21: 5.4;HSkMC: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" 3.1 3.1 3.0 0.9 3.6 0.4 2.2 5.0 2.4 2.9 2.9 2.4 0.5 3.2 2.0 1.2 2.9 1.7 2.4 2.5 3.5 1.1 1.3 2.0 0.7 3.6 3.5 6.0 1.2 2.8 1.8 3.1 3.2 1.4 0.7 2.8 2.2 2.4 2.9 2.1 1.0 1.9 3.3 1.5 1.1 0.6 3.7 0.6 2.6 1.5 0.6 1.8 2.3 3.9 0.0 0.1 16.0 0.1 0.5 0.6 0.8 1.4 0.0 0.4 0.9 0.2 0.2 1.4 5.4 0.9 0.2 0.3 0.0 0.3 1.0 0.0 0.3 0.0 0.2 0.1 1.3 0.1 0.1 3.6 1.8 0.8 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.3 0.1 1.1 0.6 0.0 0.0 0.2 0.0 0.1 2.5 0.2 0.2 0.3 0.0 0.1 0.1 0.4 1.2 0.3 2.6 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 3.0 3.6 5.0 2.4 2.5 3.5 3.6 3.5 3.2 3.3 3.7 3.9 3.6 3.2 0.5 0.0 1.0 0.0 1.5 0.0 0.0 6.9 0.6 0.4 3.9 0.0 1.3 0.0 6.2 0.2 0.6 0.4 0.0 0.7 0.0 0.6 3.8 2.6 0.0 0.0 0.0 1.2 0.1 3.3 1.1 0.5 0.0 0.4 1.4 0.7 0.3 10.1 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.2 0.0 0.0 0.1 2.7 0.0 0.0 0.0 2.0 0.1 1.2 1.5 0.8 0.1 0.3 0.7 2.5 0.0 5.2 3.2 0.2 0.5 0.3 0.1 0.1 0.7 0.8 0.4 0.8 PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 7.9;Fibroblasts: 3.4;Horizontal cells: 3.3;Skeletal myocytes: 5.9" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 86.7;HSkMC: 26.7;hTERT-RPE1: 72.4" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" 5.2 4.6 4.6 1.8 4.7 0.1 4.2 10.8 3.5 4.9 5.0 5.0 0.9 5.7 2.2 3.0 4.4 4.4 4.3 4.5 7.0 2.4 1.5 5.8 1.2 6.0 6.0 8.1 1.7 4.3 2.2 5.5 5.3 3.8 1.7 5.8 3.7 5.5 3.0 3.3 2.1 5.1 7.7 2.7 2.4 1.9 5.0 1.5 4.0 4.1 0.9 3.3 3.8 7.3 0.0 0.0 2.9 86.7 1.9 0.3 0.9 5.7 0.7 2.1 4.3 0.1 5.3 0.7 4.6 11.7 0.8 1.4 0.2 1.0 2.0 0.1 0.6 0.0 0.2 0.0 6.4 0.5 0.1 26.7 0.7 1.7 0.9 72.4 4.6 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.0 0.6 10.1 1.9 0.0 0.2 0.0 9.3 12.8 0.2 0.0 0.0 1.0 1.0 0.9 11.5 10.3 0.2 0.9 0.1 0.1 0.2 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.6 4.7 10.8 3.5 4.5 7.0 6.0 6.0 5.3 7.7 5.0 7.3 2.2 3.2 1.3 0.0 0.3 0.4 0.8 0.0 0.0 7.9 0.3 0.5 1.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 2.1 2.2 0.0 0.0 0.0 0.5 0.1 3.4 0.0 0.3 1.3 0.5 0.4 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 1.9 0.1 0.4 0.0 0.3 0.0 0.7 0.0 5.9 2.2 0.0 0.1 0.5 0.4 0.0 0.0 1.2 0.1 0.2 PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512979 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 31.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 3.3" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 9.1;SCLC-21H: 7.3;SH-SY5Y: 14.2;SuSa: 10.0" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" 0.2 1.1 17.3 0.1 12.2 0.0 0.2 19.3 14.6 0.3 0.1 0.6 0.0 0.4 0.2 0.2 0.3 0.2 2.2 12.7 13.9 0.1 0.1 0.4 0.1 12.9 21.9 0.3 0.3 0.0 1.1 0.1 10.3 0.2 0.1 6.6 0.3 0.1 0.7 0.5 0.1 0.2 22.4 0.1 0.2 0.9 14.3 0.0 0.1 0.3 0.2 0.2 0.3 31.4 0.0 0.0 0.9 0.2 0.2 0.7 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.8 0.9 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 1.3 0.0 0.0 9.1 0.5 0.0 0.0 0.1 7.3 14.2 0.1 0.0 0.1 10.0 0.1 0.3 0.1 0.8 0.1 0.2 0.6 0.2 0.0 0.2 0.6 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 12.2 19.3 14.6 12.7 13.9 12.9 21.9 10.3 22.4 14.3 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 28.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "glioma: 3.1;head and neck cancer: 0.8" "Region enhanced" "Detected in many" "hippocampal formation: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 4.6;SuSa: 7.4;U-138 MG: 14.4;U-251 MG: 6.5;U-87 MG: 8.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076140: " "unprognostic (2.86e-3)" "unprognostic (7.63e-4)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (5.42e-2)" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (3.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-9)" "unprognostic (6.87e-3)" "unprognostic (3.89e-2)" "unprognostic (3.13e-1)" "unprognostic (3.77e-3)" 0.3 0.5 5.6 0.1 8.6 0.0 0.3 0.0 11.7 0.8 0.0 1.3 0.0 1.2 0.2 0.3 0.7 0.2 5.3 28.4 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 1.2 0.1 0.0 0.5 0.0 1.2 0.4 0.5 1.2 0.5 0.2 0.7 0.0 0.1 0.3 0.6 0.3 0.1 0.2 0.2 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.3 0.3 1.5 0.1 0.8 0.5 0.4 0.5 0.0 0.0 0.4 1.4 2.2 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 4.6 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 7.4 0.1 0.2 0.1 14.4 0.2 0.2 6.5 0.0 0.0 0.0 8.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.6 0.0 11.7 28.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCIF1 "bA465L10.1, C20orf67, CAPAM, PPP1R121" ENSG00000100982 "Phosphorylated CTD interacting factor 1" Q9H4Z3 20 45934683-45948023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049517 Enhanced Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Microtubules, Cytokinetic bridge" "HPA049517: AB_2680801" "unprognostic (5.42e-3)" "unprognostic (7.76e-2)" "unprognostic (7.69e-2)" "prognostic unfavorable (8.86e-4)" "unprognostic (1.39e-2)" "unprognostic (4.20e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.57e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.50e-6)" "unprognostic (1.01e-1)" "unprognostic (4.44e-2)" "unprognostic (9.14e-3)" "unprognostic (1.24e-1)" 28.7 28.0 20.7 18.6 23.0 33.9 28.7 30.2 24.2 36.1 17.6 30.7 16.5 39.7 10.8 24.4 35.3 16.3 31.9 20.4 20.2 23.4 19.5 28.2 27.3 22.7 21.6 41.7 29.5 22.8 26.0 17.0 22.1 26.2 11.7 15.9 23.6 21.3 41.7 36.7 27.2 21.3 20.9 34.7 25.4 18.1 21.7 34.4 32.0 27.6 19.6 28.6 29.3 24.9 21.2 29.0 22.0 27.2 15.3 18.2 24.2 8.3 25.1 24.9 24.2 49.3 27.7 22.7 27.4 22.6 28.7 23.4 15.8 29.0 10.8 14.1 11.4 29.1 23.1 33.4 28.2 26.4 28.1 25.5 29.9 15.3 24.5 22.3 21.0 37.1 20.8 30.9 17.9 44.6 52.3 48.3 7.8 25.5 24.9 32.2 20.4 28.0 20.1 21.8 30.2 30.0 31.5 29.5 16.1 11.6 31.0 30.7 18.1 30.7 24.1 27.3 16.8 35.4 22.1 21.0 37.7 23.8 18.2 75.5 47.5 80.2 54.5 47.2 43.0 51.6 47.3 50.2 50.3 56.2 48.6 43.0 74.6 74.3 48.0 40.4 54.4 64.0 20.7 23.0 30.2 24.2 20.4 20.2 22.7 21.6 22.1 20.9 21.7 24.9 19.7 3.2 14.2 4.6 33.7 8.7 26.4 7.9 26.2 9.9 17.0 19.7 21.9 20.0 7.1 11.0 2.1 19.5 32.4 14.6 15.6 21.4 9.6 13.3 10.7 16.1 26.5 25.4 2.5 38.6 22.6 15.4 17.3 13.5 14.5 14.9 9.7 12.4 16.9 13.5 3.6 14.0 4.1 16.0 8.7 8.1 11.5 21.5 17.8 1.0 24.9 12.0 33.0 3.0 3.9 28.3 13.1 12.8 35.5 25.4 14.8 23.2 11.0 13.4 0.0 20.2 19.3 14.4 11.9 23.8 10.7 27.8 30.8 15.1 12.0 38.8 PCNT "KEN, KIAA0402, PCN, PCNT2, PCNTB, SCKL4" ENSG00000160299 Pericentrin O95613 21 46324141-46445769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 239.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "dendritic cells: 4.6;granulocytes: 6.0;T-cells: 8.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016820, HPA019887, HPA032101" Uncertain Supported "Centriolar satellite,Centrosome,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 37: Myocytes - Muscle contraction" Centrosome "Centriolar satellite, Cytosol" "HPA016820: AB_1855079, HPA019887: AB_1855080, HPA032101: AB_2674151" "unprognostic (9.07e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (1.30e-2)" "unprognostic (5.35e-2)" "unprognostic (3.40e-3)" "unprognostic (1.27e-2)" "unprognostic (2.59e-1)" "unprognostic (9.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.59e-3)" "unprognostic (3.86e-2)" "unprognostic (1.95e-2)" "unprognostic (5.83e-2)" "unprognostic (2.90e-1)" "unprognostic (3.36e-1)" "unprognostic (5.86e-2)" 9.7 11.1 7.6 5.9 10.5 17.7 8.9 4.2 11.9 8.6 5.3 10.7 4.1 8.2 4.3 11.7 8.5 3.6 28.3 6.0 5.4 7.7 10.9 8.2 8.2 9.0 3.9 9.6 7.8 4.3 20.3 3.5 9.5 8.2 4.3 4.6 9.7 4.2 239.2 12.3 10.1 4.4 2.6 11.5 9.5 25.6 4.7 12.5 8.4 52.0 5.5 9.6 9.2 7.4 15.4 11.6 18.0 11.1 8.9 8.8 11.3 11.6 8.0 11.3 10.0 14.2 9.7 15.2 7.3 13.4 15.3 10.8 14.6 9.9 7.8 44.9 20.4 40.2 24.1 11.3 3.1 20.6 16.1 4.8 7.5 15.2 7.6 5.5 8.8 15.8 20.9 22.4 15.8 25.4 20.6 21.3 18.0 13.9 8.0 25.3 7.2 13.5 8.7 16.3 22.1 9.8 25.4 15.7 8.0 4.4 14.8 16.0 12.1 20.4 10.2 11.7 18.9 19.3 17.2 16.4 12.6 19.9 11.1 6.0 0.6 1.2 1.5 0.5 4.6 0.3 0.7 4.8 2.0 0.1 0.5 8.8 0.4 0.4 1.0 4.6 0.8 2.0 7.6 10.5 4.2 11.9 6.0 5.4 9.0 3.9 9.5 2.6 4.7 7.4 10.5 28.9 32.0 19.9 8.6 8.3 5.7 7.0 13.6 15.0 8.9 8.6 35.7 10.0 15.3 0.0 6.2 6.4 36.7 14.0 0.0 7.1 20.4 17.0 19.9 10.1 15.6 36.2 38.1 7.6 7.4 13.1 25.0 17.8 16.4 25.4 7.1 9.0 23.3 23.5 39.0 11.2 4.1 6.9 5.5 25.6 12.8 12.7 0.0 17.8 14.7 6.8 25.7 10.6 21.9 5.7 5.7 12.0 31.4 4.2 5.7 4.1 13.0 11.1 26.3 61.3 14.2 40.5 39.8 25.0 7.1 6.4 18.8 15.1 10.4 5.1 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 21.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 255.9;Gastric mucus-secreting cells: 141.2;Paneth cells: 251.4;Proximal enterocytes: 73.0;Skeletal myocytes: 106.5;Undifferentiated cells: 103.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 1.2;cerebral cortex: 1.1" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "BEWO: 2.9;Hep G2: 2.0;U-87 MG: 4.4" "HPA048975, HPA054218" Approved Approved "Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 1.4 0.6 0.2 0.1 1.2 0.5 0.7 0.0 1.1 3.2 0.0 4.3 0.7 3.4 3.4 0.7 3.0 1.1 4.4 0.2 0.0 4.8 1.3 3.4 0.2 0.0 0.0 1.8 0.7 0.2 2.8 3.7 0.0 2.3 0.6 0.2 0.5 2.7 8.3 0.3 2.4 1.8 0.0 2.1 3.8 2.5 0.0 0.0 1.1 21.3 0.1 1.0 1.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 2.9 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.0 0.1 0.0 0.2 0.3 0.0 1.2 0.0 0.2 0.0 0.1 0.4 0.9 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.0 0.7 0.2 0.2 0.0 0.1 0.0 0.3 0.0 0.6 0.3 0.1 4.4 0.1 0.0 1.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.0 0.2 1.2 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.2 10.6 2.0 0.8 5.5 5.8 8.6 5.2 3.9 0.2 0.4 35.3 4.3 22.4 0.0 6.2 2.1 0.0 255.9 0.0 0.0 32.9 0.1 0.1 4.6 7.2 0.0 8.2 0.0 4.3 6.3 141.2 0.1 4.5 0.0 1.1 0.3 0.5 0.0 2.1 55.2 4.1 1.4 4.5 38.4 0.6 2.1 1.8 0.0 0.4 1.9 1.0 0.5 0.9 0.0 251.4 4.1 1.6 1.8 73.0 0.0 9.4 3.0 46.0 106.5 17.2 1.9 2.2 28.6 3.8 1.1 1.2 0.0 103.3 17.3 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 9.4 11.1 12.3 3.9 15.1 0.5 10.8 14.0 12.9 7.2 8.6 74.7 2.9 5.1 19.4 3.7 10.6 6.8 4.3 10.6 12.6 29.8 4.2 4.9 4.8 12.4 14.4 3.5 4.1 6.5 9.9 10.3 12.7 38.5 16.4 10.7 12.7 15.8 2.4 7.0 47.3 8.8 11.0 18.3 13.4 1.9 15.0 7.8 6.5 4.8 3.1 18.9 6.2 12.0 0.0 2.8 29.7 3.7 0.0 0.8 0.5 0.0 0.0 0.0 0.0 3.2 18.2 0.0 30.0 0.0 2.2 0.0 2.7 9.8 0.0 0.0 10.4 0.0 0.0 6.4 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 23.2 1.5 34.7 41.2 14.6 0.0 0.0 0.0 1.2 20.4 7.6 22.5 13.5 5.2 0.0 0.5 7.0 0.2 19.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.2 3.1 0.6 0.4 0.9 0.0 0.4 1.0 0.3 12.3 15.1 14.0 12.9 10.6 12.6 12.4 14.4 12.7 11.0 15.0 12.0 18.6 3.2 5.0 43.4 1.6 1.0 10.9 4.2 6.2 26.4 13.4 12.6 1.6 5.7 2.4 18.4 0.0 0.0 1.0 90.8 29.4 7.3 0.6 18.1 8.5 11.9 13.1 3.2 5.6 2.4 0.1 5.9 1.5 26.8 1.3 6.1 5.7 0.9 7.5 35.3 10.8 25.8 8.2 1.3 0.8 2.2 11.8 1.6 28.4 31.9 1.1 11.0 0.0 29.1 16.6 5.3 105.3 6.0 0.2 28.1 233.5 8.9 1.3 2.8 13.1 0.5 6.4 0.4 2.3 0.5 0.6 0.4 3.8 16.9 24.4 15.0 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDHX "DLDBP, E3BP, OPDX, PDX1, proX" ENSG00000110435 "Pyruvate dehydrogenase complex component X" O00330 11 34915829-35020591 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.6;tongue: 125.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038484, HPA038485" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Plasma membrane" Mitochondria "HPA038484: AB_10669645, HPA038485: AB_10669540" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (8.34e-3)" "unprognostic (3.56e-3)" "unprognostic (1.94e-1)" "unprognostic (2.14e-1)" "unprognostic (5.41e-2)" "unprognostic (2.60e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.83e-5)" "unprognostic (2.24e-1)" "unprognostic (8.28e-2)" "unprognostic (9.53e-2)" "unprognostic (2.82e-1)" 23.5 21.6 16.5 12.2 19.9 7.4 16.6 21.6 21.9 13.3 9.4 22.8 20.1 14.2 13.3 17.2 10.0 12.3 77.8 21.1 14.5 21.5 31.0 12.7 11.9 16.6 17.2 11.7 21.5 21.0 15.4 24.4 16.5 18.9 20.6 27.1 20.4 16.0 138.6 14.6 15.0 17.8 13.4 11.1 23.1 27.8 19.7 13.2 14.3 125.2 14.8 15.0 11.7 21.1 20.4 54.3 29.9 11.9 20.7 25.5 28.5 38.9 30.1 40.3 38.9 69.3 18.8 27.2 24.7 31.4 49.1 39.4 58.9 31.9 41.1 25.8 47.2 26.9 54.6 82.3 45.0 50.7 30.7 25.6 37.9 23.2 31.5 23.8 31.1 23.9 57.9 25.4 33.1 35.7 32.2 29.9 25.2 54.2 30.5 27.0 53.5 23.8 62.1 54.7 32.0 23.3 33.8 48.1 52.2 29.3 54.8 29.9 21.0 30.4 35.5 32.3 42.7 24.4 53.3 35.7 23.9 24.2 32.5 14.0 19.4 17.5 15.4 21.4 14.3 18.8 14.4 12.7 27.5 16.0 17.2 12.6 3.9 22.1 34.6 7.4 22.1 14.7 16.5 19.9 21.6 21.9 21.1 14.5 16.6 17.2 16.5 13.4 19.7 21.1 9.0 35.3 24.6 34.3 14.5 26.0 21.4 26.7 15.4 25.8 15.1 11.4 115.3 20.0 26.0 5.5 29.2 62.9 9.0 14.4 64.6 21.4 52.6 15.1 12.2 13.0 9.0 13.5 85.4 14.3 34.9 20.6 16.3 16.6 5.7 16.5 11.7 23.6 26.4 20.2 80.3 17.2 42.7 18.6 13.6 54.0 10.8 14.7 21.4 24.4 23.2 21.0 9.2 40.2 53.4 16.7 15.9 13.5 14.1 22.4 15.0 30.7 19.8 26.7 0.0 14.5 18.8 57.2 36.1 17.9 25.4 83.0 13.4 27.5 20.0 19.7 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 675.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 805.9;Basal respiratory cells: 763.8;Paneth cells: 769.2;Proximal enterocytes: 1059.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 189.7;memory B-cell: 223.8;naive B-cell: 213.0" "Group enriched" "Detected in all" 7 "B-cells: 223.8;granulocytes: 189.7" "Cell line enhanced" "Detected in many" "HaCaT: 766.3;Hep G2: 635.3;HHSteC: 731.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 93000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: AB_1855147" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" "prognostic favorable (1.14e-5)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (8.99e-2)" "unprognostic (2.26e-1)" "unprognostic (2.82e-3)" "unprognostic (5.77e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" 301.7 32.4 10.7 91.5 10.8 25.0 236.0 10.2 18.5 133.1 30.2 220.0 179.4 115.0 91.8 182.3 155.3 114.9 393.2 11.7 10.9 82.8 160.3 337.2 104.5 20.4 12.7 35.6 98.3 65.9 29.5 141.1 14.1 116.9 218.5 36.9 166.1 114.7 675.1 136.8 249.0 146.0 14.0 148.3 148.3 13.7 13.8 105.9 194.7 290.0 123.7 276.3 165.3 11.2 274.4 181.8 12.4 0.4 64.1 43.3 277.1 82.6 266.4 218.8 356.5 387.0 429.8 0.3 21.9 233.8 110.4 766.3 91.5 498.1 220.6 0.2 132.0 277.9 50.1 635.3 731.0 0.1 13.2 125.5 257.0 111.9 400.6 233.2 396.8 24.2 60.0 70.3 52.7 51.4 0.8 4.9 24.6 137.7 137.2 234.1 10.0 98.4 114.4 268.9 48.3 18.9 91.2 84.6 0.9 293.8 68.2 125.7 345.1 84.5 19.7 0.7 0.7 31.2 0.1 91.6 92.5 0.2 41.0 0.4 2.4 189.7 11.9 0.8 0.1 223.8 2.3 14.1 31.0 213.0 0.5 8.1 7.5 8.9 1.5 3.2 2.2 44.5 10.7 10.8 10.2 18.5 11.7 10.9 20.4 12.7 14.1 14.0 13.8 11.2 435.0 76.9 123.5 0.0 145.6 366.3 805.9 763.8 244.7 10.1 100.6 131.4 266.2 223.1 250.2 51.5 29.2 538.2 20.5 657.0 15.6 420.1 8.4 218.6 319.3 359.3 101.3 41.6 0.9 172.5 116.7 149.2 100.9 113.0 12.6 47.2 459.7 100.4 50.0 1.7 0.4 488.9 152.5 19.4 105.2 8.0 5.0 88.8 40.9 2.8 8.8 11.6 32.0 0.0 0.0 227.0 769.2 0.7 103.5 256.5 1059.7 109.0 316.4 59.5 315.5 21.0 213.1 4.3 35.7 170.4 197.9 117.0 25.8 1.9 419.2 554.3 PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 629.5;skeletal muscle: 1163.5;tongue: 576.0" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 1844.2" "Cancer enriched" "Detected in all" 8 "prostate cancer: 132.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 219.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 219.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1200000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: AB_2533388, HPA016740: AB_1855153, HPA020026: AB_1855154" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.08e-2)" "unprognostic (6.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.46e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.11e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" 41.7 26.0 20.5 25.6 25.2 59.7 39.5 22.4 22.4 27.4 84.9 34.1 33.3 94.8 11.3 72.3 40.5 47.5 629.5 21.4 27.7 34.9 82.7 22.0 16.2 30.9 30.1 27.2 30.2 12.2 17.5 67.7 25.0 88.5 30.8 18.2 40.2 68.9 1163.5 21.5 34.4 105.9 22.7 24.1 31.0 12.7 26.3 10.9 25.5 576.0 21.1 45.8 27.6 21.0 31.4 87.2 33.6 13.0 71.7 51.3 13.0 71.6 59.9 40.1 32.6 80.8 66.3 12.0 72.0 72.3 21.0 31.8 46.5 68.2 65.9 24.1 19.3 43.7 53.8 32.2 103.7 14.6 38.3 66.4 58.4 96.1 74.0 177.9 93.5 13.2 19.2 12.5 86.2 29.8 15.0 4.8 11.4 66.7 36.6 7.2 24.7 11.1 45.0 94.6 16.5 21.8 38.9 88.7 20.3 26.7 10.3 5.2 113.7 103.7 17.3 46.1 44.1 9.5 13.0 12.7 56.5 10.3 24.9 219.7 23.4 21.0 12.1 40.6 9.7 10.5 12.0 12.8 19.5 7.6 7.9 10.4 22.6 9.2 44.6 6.6 11.8 15.2 20.5 25.2 22.4 22.4 21.4 27.7 30.9 30.1 25.0 22.7 26.3 21.0 107.4 44.8 23.6 184.1 22.1 194.4 380.3 92.1 63.7 4.7 90.2 67.4 1844.2 62.9 82.9 49.7 31.3 13.7 18.5 180.0 13.7 95.0 19.2 68.7 11.8 117.2 109.4 27.6 4.9 95.1 96.5 97.8 84.6 108.7 52.0 29.1 137.8 207.0 38.8 1.7 20.7 107.4 36.7 60.6 75.3 9.1 41.3 59.8 62.2 104.0 41.6 86.2 12.3 181.5 43.1 139.2 166.8 66.5 23.2 300.7 117.5 73.6 70.0 35.8 78.9 96.7 134.7 23.8 34.4 107.3 157.0 23.8 31.1 6.8 74.0 217.5 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Basal respiratory cells: 98.5;Fibroblasts: 123.1;monocytes: 116.3;Muller glia cells: 97.7;Peritubular cells: 62.8" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 149.5;EFO-21: 356.4;HAP1: 253.3;HHSteC: 216.0;NTERA-2: 116.0;SuSa: 119.0;TIME: 242.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" 61.5 3.3 8.9 55.9 9.3 0.0 20.9 13.7 8.1 43.1 23.5 16.6 3.8 25.9 11.3 15.8 33.4 42.1 20.3 8.0 14.6 3.4 0.6 32.4 9.8 24.9 15.6 29.4 6.4 1.1 3.3 135.6 19.1 14.0 10.6 22.7 9.1 14.1 30.0 20.0 15.9 34.5 16.4 0.3 24.7 4.5 22.5 10.3 6.2 11.3 18.5 96.1 25.2 21.2 0.1 0.0 149.5 0.1 0.5 0.0 0.1 2.4 0.1 0.0 0.0 0.0 0.1 0.2 356.4 9.0 0.1 0.7 253.3 44.7 0.0 1.0 46.1 0.1 0.0 0.0 216.0 0.0 0.2 29.5 82.9 18.6 21.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 116.0 0.0 0.6 0.3 0.2 0.1 0.0 4.0 0.1 0.1 0.2 0.0 0.3 119.0 0.1 0.6 242.2 41.8 34.6 0.6 0.1 0.1 0.3 1.0 88.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.9 9.3 13.7 8.1 8.0 14.6 24.9 15.6 19.1 16.4 22.5 21.2 2.4 105.8 11.2 3.9 0.2 14.5 30.4 98.5 14.8 1.4 0.5 19.9 8.4 2.8 18.8 0.0 4.2 2.0 0.1 0.0 0.0 0.5 0.7 1.6 37.6 22.4 0.0 0.0 2.6 0.0 2.1 123.1 0.0 2.8 1.3 3.4 6.4 0.0 6.5 0.0 3.5 0.0 8.2 0.0 14.0 1.8 20.2 5.3 7.2 5.6 116.3 97.7 0.0 19.6 0.2 0.4 0.0 62.8 0.0 15.8 0.0 0.0 5.4 3.4 0.0 17.0 8.4 1.0 8.2 3.9 7.0 2.9 1.3 0.9 0.0 3.4 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PEF1 PEF1A ENSG00000162517 "Penta-EF-hand domain containing 1" Q9UBV8 1 31629866-31644896 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061608 Supported Nucleoplasm,Vesicles,Cytosol NA NA 570000 "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA061608: AB_2684567" "unprognostic (2.92e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" "unprognostic (8.40e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (5.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.79e-2)" "unprognostic (1.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.35e-1)" "unprognostic (8.85e-3)" "unprognostic (2.38e-1)" "unprognostic (1.60e-1)" "unprognostic (2.89e-3)" 57.3 67.1 76.4 28.5 78.6 37.9 56.4 80.1 81.3 56.3 77.8 59.0 31.3 63.3 84.4 62.1 54.6 38.6 63.8 77.9 81.6 69.4 71.3 61.3 38.5 81.9 78.6 50.2 40.9 69.1 52.1 61.4 84.7 59.4 45.1 26.6 39.9 59.1 42.5 85.7 44.0 60.0 79.9 55.9 51.3 40.1 78.9 56.6 110.9 39.3 61.6 61.9 52.2 81.4 56.9 65.0 53.1 41.3 61.2 63.8 51.0 52.8 89.8 124.4 109.0 38.7 83.2 60.2 71.9 118.3 63.9 58.1 103.9 134.5 100.1 76.0 112.6 49.9 49.4 78.6 107.9 49.0 45.3 66.3 152.6 122.0 113.2 79.2 122.2 72.6 52.4 60.6 90.4 67.1 75.6 47.5 74.3 69.7 72.9 72.5 51.7 66.2 98.6 60.8 75.8 43.9 60.2 56.1 81.0 82.9 50.0 35.5 65.7 54.0 46.0 92.7 71.3 38.7 42.2 65.4 67.7 71.8 65.9 147.3 75.6 93.0 90.2 69.4 86.8 70.9 75.5 81.4 77.5 76.4 70.2 70.6 76.2 87.4 67.2 71.4 84.0 104.8 76.4 78.6 80.1 81.3 77.9 81.6 81.9 78.6 84.7 79.9 78.9 81.4 58.2 41.7 37.7 5.9 31.6 36.2 66.6 70.8 29.6 41.2 34.7 36.2 20.4 21.5 35.3 69.9 12.5 160.0 33.9 36.6 113.5 72.0 81.3 17.4 20.0 60.3 44.3 40.0 8.0 61.9 106.1 34.0 21.9 19.8 72.9 34.3 35.3 24.4 61.9 53.8 7.4 49.8 50.8 18.5 21.8 87.5 45.1 27.8 49.8 7.5 81.6 59.6 46.4 6.0 13.8 59.1 44.0 58.6 23.6 65.4 48.9 57.8 23.5 26.5 19.7 25.8 38.8 44.1 44.2 24.6 51.4 182.8 33.6 50.9 39.5 58.3 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 228.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.1;Plasma cells: 318.8;Squamous epithelial cells: 208.0;Suprabasal keratinocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 76.9" "Group enriched" "Detected in all" 4 "granulocytes: 76.9;monocytes: 23.2" "Cell line enhanced" "Detected in many" "CACO-2: 58.8;U-698: 146.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 27.6 7.9 10.2 28.1 14.4 228.5 25.7 11.9 13.5 17.9 9.2 18.6 17.6 17.3 8.6 42.9 12.7 26.1 11.8 13.8 11.2 10.6 13.5 31.0 24.7 12.2 11.2 5.5 9.3 37.9 15.8 15.6 12.2 8.9 20.1 5.1 18.9 7.7 7.1 29.7 23.2 13.9 12.6 21.8 18.1 10.7 10.9 28.3 9.7 10.0 29.0 22.4 23.7 15.6 3.6 2.8 36.5 24.6 4.2 3.2 8.3 4.8 5.4 4.3 6.8 58.8 4.1 48.3 11.3 1.7 1.6 5.8 11.1 10.5 8.6 12.2 8.9 4.4 1.7 9.5 12.4 4.8 8.3 4.2 8.1 6.4 21.6 4.5 24.3 18.2 2.7 11.7 3.7 0.3 10.6 6.9 23.8 11.1 1.7 13.2 12.6 28.1 17.7 10.8 16.7 23.3 3.6 5.5 12.9 11.3 3.0 3.3 17.5 4.0 5.7 4.0 7.1 27.0 2.8 146.7 2.1 4.3 10.9 15.0 15.6 15.0 0.9 14.1 1.7 8.5 4.8 1.9 5.4 6.6 5.6 2.5 76.9 3.0 23.2 0.5 11.6 6.6 10.2 14.4 11.9 13.5 13.8 11.2 12.2 11.2 12.2 12.6 10.9 15.6 94.5 28.9 49.2 4.6 84.4 224.1 74.6 48.2 105.9 1.7 60.9 50.3 5.7 15.7 52.0 5.5 0.0 1.7 16.9 57.9 1.9 5.3 10.6 34.6 26.4 52.1 25.7 3.4 23.4 26.7 8.6 24.5 75.4 58.7 15.2 6.3 37.5 7.5 22.8 3.3 19.1 23.4 30.5 67.6 103.7 11.2 1.5 107.0 112.1 119.9 30.6 5.5 3.1 82.9 67.9 20.9 45.9 1.9 318.8 44.7 32.7 9.6 43.6 2.0 0.0 10.1 51.9 8.4 9.6 208.0 217.5 4.0 49.4 3.2 32.4 145.8 PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301524 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Microglial cells: 100.2;Oligodendrocyte precursor cells: 150.8;Oligodendrocytes: 77.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 33.3;JURKAT: 43.8;MOLT-4: 39.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (9.21e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-2)" "unprognostic (3.36e-3)" "unprognostic (1.81e-1)" "unprognostic (2.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" "prognostic favorable (1.53e-6)" "unprognostic (3.64e-1)" "unprognostic (2.15e-1)" "unprognostic (5.43e-2)" "unprognostic (2.22e-1)" 11.6 3.0 8.1 4.3 7.8 18.6 7.7 27.9 5.9 6.7 5.4 7.0 11.0 6.7 2.5 4.4 6.3 10.0 2.9 5.6 6.6 9.2 2.8 6.7 4.0 8.8 10.9 15.0 28.6 1.9 2.7 3.1 9.3 4.7 3.9 15.1 7.7 3.5 2.4 5.9 9.2 3.3 8.0 6.8 14.4 10.0 10.4 19.1 4.1 3.8 2.0 10.6 5.7 9.2 0.1 3.1 8.8 0.0 4.8 7.2 0.2 1.2 4.2 0.9 0.1 0.2 0.7 0.2 4.2 2.5 0.0 0.9 6.9 0.0 0.4 2.3 2.4 7.9 13.0 0.0 4.1 1.1 33.3 4.5 0.4 0.0 0.0 4.8 1.6 43.8 6.0 0.1 0.9 0.0 39.5 0.4 14.5 0.1 1.2 19.2 0.5 1.8 3.6 15.4 17.5 0.0 0.8 0.1 10.2 5.5 0.0 6.3 0.5 2.6 4.4 0.8 4.4 0.7 0.1 1.0 4.6 5.4 2.6 0.9 1.9 2.4 0.3 1.0 0.5 0.1 0.3 0.2 1.3 0.4 0.2 0.1 5.6 0.3 0.8 0.3 0.0 0.7 8.1 7.8 27.9 5.9 5.6 6.6 8.8 10.9 9.3 8.0 10.4 9.2 13.9 0.0 10.0 114.3 7.7 14.3 10.4 1.7 9.6 30.7 7.1 7.7 2.7 8.6 6.7 12.9 29.2 0.1 11.8 15.0 3.9 5.9 3.7 23.7 14.5 18.0 7.2 5.5 13.5 14.1 0.1 13.5 34.1 21.2 5.7 5.7 17.5 1.0 1.2 21.9 22.1 7.9 2.0 19.7 14.0 5.7 17.1 20.3 17.8 100.2 22.9 9.7 10.3 150.8 77.5 9.1 6.0 18.0 5.6 7.8 12.4 10.1 8.8 19.7 13.1 5.4 22.0 2.0 24.0 4.7 18.3 0.1 6.2 5.6 3.1 12.6 PELI3 MGC35521 ENSG00000174516 "Pellino E3 ubiquitin protein ligase family member 3" Q8N2H9 11 66466327-66477337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 26.5;Horizontal cells: 21.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033750, HPA038875, HPA062281" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles" Nucleoli "CAB033750: AB_2161361, HPA038875: AB_2676249, HPA062281: AB_2684735" "unprognostic (1.15e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-2)" "unprognostic (1.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.19e-3)" "unprognostic (7.91e-3)" "prognostic favorable (8.19e-4)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.01e-2)" 7.5 10.2 19.1 2.6 18.7 1.2 7.7 21.1 33.2 12.4 4.4 15.3 3.2 13.9 5.6 6.9 11.2 6.8 8.8 20.5 15.0 6.2 4.2 5.5 3.2 22.7 17.2 13.5 8.2 11.7 13.4 2.4 23.6 14.6 1.7 5.5 8.7 14.8 18.3 7.7 6.3 5.6 13.9 5.1 9.4 7.6 19.5 1.0 6.3 4.6 1.5 14.7 9.1 19.8 20.2 8.1 6.5 5.0 10.2 4.0 5.6 6.2 8.0 5.7 4.9 11.8 4.3 5.0 6.1 6.9 10.3 10.2 4.0 7.8 2.4 9.6 4.1 1.3 7.2 3.5 6.4 1.0 9.2 3.8 8.6 5.8 2.1 8.3 1.2 6.4 2.3 7.2 2.5 11.5 4.2 3.0 3.9 10.2 8.4 13.6 4.7 5.2 3.2 6.3 7.9 4.4 3.2 8.8 21.6 2.8 10.3 5.3 3.4 5.0 7.6 21.7 5.4 6.9 4.2 2.7 10.6 3.1 4.1 0.5 1.0 0.2 1.0 0.8 0.8 1.2 0.8 1.2 1.4 1.5 0.9 0.7 0.0 0.5 3.4 0.4 1.0 0.6 19.1 18.7 21.1 33.2 20.5 15.0 22.7 17.2 23.6 13.9 19.5 19.8 5.0 6.4 2.0 2.0 0.7 1.7 3.8 0.9 4.0 13.3 3.0 4.4 8.1 4.3 0.6 0.0 10.4 2.5 0.4 0.6 1.9 3.2 5.0 0.4 2.6 2.7 26.5 0.0 7.1 2.5 2.1 4.2 2.0 1.1 0.0 2.9 3.3 2.8 3.3 21.9 7.7 1.4 2.0 1.9 1.4 10.4 7.5 2.9 0.0 1.9 2.8 7.5 0.0 2.0 2.5 1.8 1.4 9.8 1.0 2.5 0.9 2.9 0.2 9.7 6.6 3.1 4.9 3.0 3.5 1.8 0.3 0.3 1.3 1.5 0.8 1.5 PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 166.2;liver: 267.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 122.9;Hepatocytes: 220.1;Peritubular cells: 346.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: AB_10796905, HPA073930: " "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favorable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" 71.6 33.9 13.2 5.2 13.6 9.2 92.7 16.3 20.0 47.4 12.7 13.6 15.0 36.9 166.2 26.8 26.5 5.4 24.5 13.0 15.2 30.2 267.4 25.8 5.2 14.9 15.3 27.9 32.2 13.3 24.7 7.3 16.8 30.8 3.4 2.8 27.1 24.0 29.5 34.3 13.7 6.8 15.1 12.8 19.5 40.8 14.2 5.6 33.5 10.7 4.5 21.1 24.2 17.2 34.3 64.7 16.5 43.4 34.6 23.8 25.1 21.6 19.0 28.5 22.4 38.2 22.6 29.8 38.1 21.9 21.6 39.9 24.6 12.8 7.2 22.2 86.9 14.8 33.2 55.4 38.4 13.5 21.4 24.9 26.7 19.2 29.1 9.7 15.7 41.3 14.6 12.3 12.9 66.0 23.9 24.2 23.2 65.5 52.4 22.2 26.7 27.5 24.1 12.5 16.7 39.5 15.3 10.1 39.2 31.5 15.6 5.1 13.9 28.1 28.2 47.4 18.9 17.0 12.1 5.5 25.9 18.5 23.6 1.9 41.1 2.1 16.9 39.0 24.8 23.5 22.2 21.5 30.5 28.3 17.2 19.4 3.1 29.3 28.0 27.7 22.4 21.3 13.2 13.6 16.3 20.0 13.0 15.2 14.9 15.3 16.8 15.1 14.2 17.2 38.1 16.0 17.5 4.9 12.4 18.2 21.0 27.9 39.3 4.5 33.0 45.1 15.5 11.5 24.9 27.6 0.0 19.5 5.9 9.3 17.6 33.3 2.9 21.8 122.9 18.5 68.8 17.1 5.4 38.5 21.6 30.4 8.2 23.8 12.7 52.4 10.4 220.1 23.5 5.0 6.8 30.9 24.4 13.7 12.2 14.9 94.8 11.2 21.4 3.7 5.7 34.7 2.1 9.5 4.0 25.7 10.8 346.8 15.3 35.1 21.7 32.3 14.2 6.1 6.6 20.0 23.6 21.0 24.9 39.5 18.2 14.6 12.5 49.3 24.1 23.8 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 33.3 41.0 26.3 29.2 28.6 35.5 32.2 26.7 30.5 31.8 27.1 29.6 21.7 35.5 21.2 43.6 29.4 20.2 28.8 26.9 26.2 38.7 48.2 26.2 32.3 27.1 27.2 34.2 57.3 30.1 21.8 21.5 27.6 32.9 19.6 9.2 29.3 21.5 48.8 45.3 28.2 22.5 25.8 34.4 35.7 40.0 27.0 23.8 27.1 20.0 27.3 35.0 31.9 30.0 132.2 146.6 53.0 113.7 59.9 58.4 81.6 84.7 69.6 141.6 110.0 170.6 55.2 177.2 74.4 97.0 110.3 89.4 163.9 153.5 103.1 76.4 159.8 85.9 80.8 149.0 149.3 209.6 86.8 82.7 94.7 148.3 147.3 68.3 93.0 62.4 144.6 69.9 87.7 164.3 102.6 209.8 103.1 128.3 106.7 129.0 91.7 173.3 78.9 88.7 91.4 94.6 84.2 94.6 117.8 42.0 66.8 106.1 74.2 165.9 126.1 85.3 145.1 88.1 81.0 178.6 116.2 94.9 109.0 7.5 24.9 6.4 18.9 29.8 23.2 20.2 17.4 18.1 26.8 20.0 19.4 18.0 0.9 20.0 22.3 23.2 14.3 29.3 26.3 28.6 26.7 30.5 26.9 26.2 27.1 27.2 27.6 25.8 27.0 30.0 23.6 3.2 18.9 4.9 17.4 22.6 23.4 32.7 22.2 6.5 14.1 12.2 3.8 24.3 22.1 25.8 8.4 34.9 7.8 19.6 25.4 48.0 44.4 11.7 13.8 23.2 23.4 24.6 4.3 43.9 40.0 15.4 22.4 10.6 18.3 24.4 27.8 22.8 38.4 3.3 4.3 22.4 22.4 27.8 12.6 14.3 19.9 21.2 21.4 2.8 29.0 13.5 16.5 6.6 5.1 38.7 16.2 20.3 28.3 26.4 31.3 55.1 24.6 8.9 19.7 23.2 20.7 28.7 20.9 25.9 22.9 28.5 13.5 19.9 29.7 15.1 PEX6 "PAF-2, PXAAA1" ENSG00000124587 "Peroxisomal biogenesis factor 6" Q13608 6 42963865-42979181 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025924, HPA074179" Supported Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA025924: AB_1855230, HPA074179: " "unprognostic (7.32e-3)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (9.16e-2)" "unprognostic (9.18e-2)" "unprognostic (3.27e-1)" "unprognostic (8.88e-2)" "unprognostic (5.92e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "unprognostic (7.24e-3)" "unprognostic (5.31e-2)" "unprognostic (3.79e-3)" "unprognostic (1.86e-1)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (1.55e-1)" 11.6 20.5 24.9 9.2 25.2 9.5 12.1 23.9 27.7 19.1 25.5 16.3 9.3 15.5 7.7 16.4 22.7 9.6 18.7 25.1 25.5 16.5 27.7 10.0 14.5 27.2 25.5 26.1 76.2 15.2 24.3 9.6 24.2 21.6 7.8 9.9 14.8 11.4 23.4 14.0 16.3 9.6 23.9 17.5 16.3 16.2 25.1 14.7 19.8 15.0 10.4 17.3 15.7 25.2 35.0 16.4 8.1 30.6 29.6 28.3 8.4 6.0 9.4 4.8 10.0 10.5 10.1 14.1 8.2 14.3 20.5 32.2 28.7 31.1 5.0 27.6 15.2 4.7 24.4 6.2 20.0 4.8 9.4 35.5 35.5 19.9 5.5 39.1 24.7 18.9 25.2 14.1 10.7 3.9 12.7 15.8 10.0 78.8 14.3 26.8 14.3 5.8 12.3 10.0 25.4 11.1 5.6 21.9 32.7 13.1 43.2 21.2 14.0 15.2 2.9 7.5 14.0 21.0 19.8 19.7 5.2 24.6 12.4 1.3 1.3 2.1 1.2 1.1 2.1 1.0 1.8 2.5 1.9 1.9 2.2 2.1 0.8 2.0 0.7 1.0 0.9 1.1 24.9 25.2 23.9 27.7 25.1 25.5 27.2 25.5 24.2 23.9 25.1 25.2 5.6 6.4 2.6 19.9 5.6 5.0 10.2 6.2 10.8 15.2 11.8 12.7 4.1 10.0 5.6 7.3 2.1 11.4 5.4 10.2 13.7 2.8 2.5 17.6 10.6 5.8 5.4 1.7 24.6 1.5 6.7 9.2 11.2 9.1 0.0 19.8 8.6 14.1 5.8 21.9 22.4 8.5 6.1 9.7 3.2 3.6 14.6 5.4 8.8 9.4 4.5 11.8 9.2 13.0 16.6 1.9 10.4 9.4 3.1 6.3 15.1 13.9 14.3 7.0 0.0 13.0 6.6 7.3 2.6 6.3 5.5 7.4 7.8 26.1 10.5 6.6 PFDN1 PFD1 ENSG00000113068 "Prefoldin subunit 1" O60925 5 140245035-140303113 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006499 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" Nucleoli "HPA006499: AB_1079596" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.11e-2)" "unprognostic (5.66e-3)" "prognostic unfavorable (8.81e-5)" "unprognostic (2.12e-2)" "unprognostic (2.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (4.10e-1)" "unprognostic (8.60e-3)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.00e-1)" 74.1 50.9 73.9 37.7 75.6 60.2 50.0 82.2 88.4 41.4 70.8 59.2 40.2 50.8 54.3 52.3 41.9 35.7 93.3 77.2 79.7 61.6 38.5 46.9 46.1 82.9 77.2 37.2 34.7 52.8 39.4 50.8 80.5 44.8 42.9 35.1 45.4 43.7 149.0 46.2 39.8 61.4 79.1 36.6 40.7 29.9 79.3 51.5 42.4 86.4 51.6 45.9 40.9 81.2 172.4 79.6 137.7 80.9 89.7 91.8 133.8 229.6 114.9 174.6 192.6 172.1 107.9 114.9 224.1 124.3 180.0 62.6 102.0 228.7 204.2 122.6 102.9 102.4 76.5 113.0 105.1 213.5 76.4 98.2 119.8 148.5 156.3 112.6 196.0 132.8 93.7 73.1 149.8 78.5 146.0 147.6 92.0 70.3 119.2 101.3 195.9 86.3 197.1 77.9 78.2 81.8 172.1 148.6 136.8 128.5 102.1 122.3 249.1 121.8 119.6 71.9 208.0 70.3 198.6 299.2 122.5 138.5 144.1 149.5 84.7 130.3 86.2 131.1 91.8 106.0 98.6 100.4 100.5 97.9 97.3 88.4 14.0 114.7 130.3 93.0 129.3 115.5 73.9 75.6 82.2 88.4 77.2 79.7 82.9 77.2 80.5 79.1 79.3 81.2 87.9 67.3 33.0 16.3 57.4 38.0 65.9 96.2 30.7 42.5 50.1 57.3 81.3 52.9 62.1 66.2 45.9 116.1 53.1 56.6 123.3 121.9 3.9 58.0 56.6 73.8 46.6 62.9 31.2 101.7 86.6 55.4 35.2 70.9 54.4 53.6 72.1 56.9 85.4 25.2 29.3 43.6 48.8 61.1 37.7 12.9 52.2 63.4 74.7 37.5 90.4 84.9 71.1 24.1 39.3 128.9 55.1 52.3 35.5 45.4 80.9 147.3 45.3 42.9 65.7 39.6 63.7 23.7 61.8 40.8 34.9 85.6 45.2 42.9 47.3 63.6 PFDN6 "H2-KE2, HKE2, KE-2, PFD6" ENSG00000204220 "Prefoldin subunit 6" O15212 6 33289302-33298401 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 220.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043032, HPA048123" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 89000 "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Golgi apparatus" Cytosol "HPA043032: AB_2678278, HPA048123: AB_2680273" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (7.66e-2)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.35e-2)" "unprognostic (8.29e-2)" "unprognostic (3.36e-1)" "unprognostic (1.55e-1)" "prognostic favorable (1.01e-4)" "unprognostic (6.93e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (8.97e-4)" "unprognostic (1.79e-1)" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (4.68e-3)" 45.3 78.2 23.7 13.7 24.4 12.9 45.4 24.2 27.3 49.2 22.6 55.9 9.3 54.8 14.2 70.2 46.2 6.7 85.1 24.4 24.4 78.8 98.1 41.7 15.9 24.6 24.6 45.3 51.7 14.4 62.7 13.6 24.7 51.0 11.6 8.6 47.6 8.0 129.3 49.6 45.3 9.9 23.7 49.9 58.4 91.4 24.0 17.1 45.6 14.7 17.0 55.6 46.7 25.2 49.4 36.0 34.9 56.7 22.7 17.3 43.4 37.2 20.6 48.0 48.7 42.6 24.0 102.8 43.1 20.5 83.5 42.2 69.5 47.6 58.3 49.3 52.9 89.8 39.4 78.3 33.2 56.3 49.3 20.7 50.9 64.8 41.6 28.5 40.2 61.2 107.2 29.6 36.7 36.0 73.9 58.7 47.7 33.0 37.6 71.9 38.0 65.2 58.9 23.4 61.3 83.9 32.1 83.3 61.3 35.0 44.4 65.0 22.5 24.7 36.0 26.0 68.7 71.2 220.3 89.4 20.5 71.9 38.1 1.8 2.6 1.8 1.9 3.2 2.1 3.3 2.3 3.1 2.4 3.2 1.8 2.5 1.1 2.1 3.5 3.5 3.5 1.9 23.7 24.4 24.2 27.3 24.4 24.4 24.6 24.6 24.7 23.7 24.0 25.2 17.4 25.6 8.7 5.2 49.1 55.7 45.2 92.6 43.9 24.5 30.2 17.1 20.7 60.1 51.6 55.2 10.4 127.5 37.6 90.0 121.3 87.6 94.2 106.5 64.7 30.6 50.4 48.4 4.3 103.8 126.1 32.6 44.4 66.9 61.6 32.9 19.2 74.0 79.2 18.5 4.1 75.7 87.5 35.4 45.2 42.7 61.8 37.2 71.2 2.8 66.3 51.0 50.4 1.5 7.1 88.0 71.3 49.2 55.3 53.9 76.4 210.0 53.0 29.0 39.5 43.6 96.3 208.2 60.4 64.3 63.9 110.8 36.9 47.4 82.7 46.7 PGAM2 PGAM-M ENSG00000164708 "Phosphoglycerate mutase 2" P15259 7 44062727-44065567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "heart muscle: 1132.9;skeletal muscle: 4350.5;tongue: 1754.5" "Group enriched" "Detected in many" 6 "Early spermatids: 539.1;Late spermatids: 1891.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 65.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043801, HPA050314, HPA060173" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA 38000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Cytosol" "HPA043801: , HPA050314: AB_2732558, HPA060173: AB_2684215" 4.1 3.7 32.9 0.1 37.7 0.1 2.9 40.9 43.1 2.8 28.9 2.1 2.0 1.8 0.7 58.9 2.3 2.4 1132.9 29.3 45.0 10.6 1.8 2.0 0.3 33.8 39.8 2.0 2.1 4.0 13.5 0.1 46.0 16.5 0.3 4.3 33.6 0.6 4350.5 1.8 1.3 0.5 30.8 1.2 1.7 193.9 46.8 23.9 5.1 1754.5 0.5 0.7 1.9 39.8 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 65.8 7.0 0.0 0.3 0.4 0.1 0.7 0.0 0.0 0.0 0.2 0.1 0.0 1.0 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 32.9 37.7 40.9 43.1 29.3 45.0 33.8 39.8 46.0 30.8 46.8 39.8 0.7 0.0 0.0 6.8 1.2 1.1 0.3 0.1 0.6 15.6 0.2 0.6 0.0 0.0 0.3 0.0 10.4 0.0 0.0 0.2 80.3 0.1 539.1 4.0 0.4 1.5 22.9 0.0 0.1 0.5 0.0 0.6 1.5 5.6 0.0 0.4 0.0 0.3 0.0 0.0 0.7 0.4 4.1 0.3 1.4 1891.7 7.8 1.5 1.8 1.9 0.0 5.6 0.0 1.0 0.5 0.3 1.2 6.0 1.4 0.2 0.4 9.2 0.1 4.6 26.3 78.3 18.6 187.6 7.0 0.2 0.6 0.0 0.6 0.1 0.2 0.5 PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 50.5;thyroid gland: 52.5" "Group enriched" "Detected in many" 11 "Extravillous trophoblasts: 1604.4;Syncytiotrophoblasts: 2122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "BEWO: 422.4;HUVEC TERT2: 199.1" "Low region specificity" "Detected in all" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" No No 20800 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" 11.8 4.9 7.4 7.8 7.6 0.1 11.3 7.3 11.7 22.4 20.2 7.0 2.4 7.6 1.4 10.0 21.8 5.9 18.8 8.7 20.6 8.1 6.0 7.2 6.4 9.5 15.7 6.4 4.9 8.4 5.5 50.5 9.3 19.3 2.0 1.2 10.5 10.3 9.9 15.7 12.5 7.8 7.0 3.3 4.8 3.2 8.6 3.9 52.5 5.9 3.3 13.6 14.8 7.8 1.4 1.5 1.3 1.3 2.0 0.2 422.4 4.0 3.6 1.8 2.2 10.9 0.6 0.3 9.1 2.8 0.2 0.5 1.8 19.2 1.6 0.2 2.4 0.0 0.1 11.3 1.5 0.2 11.0 4.7 4.5 7.5 1.8 0.5 199.1 0.0 0.0 0.1 55.6 0.9 0.0 0.5 2.1 0.1 3.4 0.2 51.3 0.0 0.5 1.0 31.0 17.0 0.0 0.8 7.7 25.0 0.1 0.5 40.6 0.3 10.2 0.1 17.0 0.4 0.2 0.7 6.3 0.5 0.5 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 7.4 7.6 7.3 11.7 8.7 20.6 9.5 15.7 9.3 7.0 8.6 7.8 32.4 9.6 4.6 1.0 1.0 24.6 10.3 111.4 34.7 1.3 8.9 16.0 3.6 0.0 26.0 0.0 14.6 83.8 2.4 2.0 0.0 2.7 0.1 1.1 3.3 169.4 7.1 2.7 0.1 0.5 1604.4 30.8 1.1 0.8 6.3 0.2 5.3 0.3 37.4 0.0 0.2 2.1 18.3 0.6 8.9 0.8 13.1 2.1 21.4 0.0 0.0 1.9 0.0 0.0 0.2 0.5 1.2 19.5 0.2 3.2 0.6 1.1 12.1 7.8 105.2 7.1 86.4 0.2 6.8 8.1 19.6 2122.6 3.0 3.0 2.3 5.8 PGGT1B "BGGI, GGTI" ENSG00000164219 "Protein geranylgeranyltransferase type I subunit beta" P53609 5 115204012-115262877 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 111.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030646 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Endoplasmic reticulum" Cytosol "HPA030646: AB_10602019" "unprognostic (2.73e-2)" "unprognostic (1.67e-1)" "unprognostic (3.92e-2)" "unprognostic (7.34e-2)" "unprognostic (5.57e-2)" "unprognostic (7.56e-3)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (3.25e-2)" "unprognostic (1.33e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-1)" "unprognostic (4.38e-2)" "unprognostic (1.58e-1)" "unprognostic (3.75e-1)" "unprognostic (5.93e-3)" "unprognostic (1.15e-2)" 9.4 8.1 4.6 11.1 6.1 12.8 9.6 6.1 4.2 7.6 5.6 14.6 13.0 8.0 3.6 9.6 7.5 7.4 6.7 4.2 5.9 8.1 12.8 7.4 9.8 5.3 5.9 7.3 9.6 12.6 3.2 8.3 6.4 8.4 15.1 12.0 6.6 5.9 7.8 4.9 11.1 9.8 5.8 10.3 11.7 5.6 5.6 9.4 8.6 9.1 11.0 11.3 5.4 6.8 14.7 15.6 17.5 22.7 10.0 8.3 8.6 17.7 10.4 14.5 14.8 17.1 15.3 29.6 23.4 12.4 14.9 11.2 23.3 23.3 21.5 32.9 12.9 17.1 21.0 13.9 13.3 23.7 24.2 12.5 14.0 14.3 14.8 9.2 14.7 17.2 14.1 12.3 16.7 22.8 20.9 7.9 13.0 16.4 12.0 22.6 23.3 30.3 15.2 27.3 17.0 13.0 21.0 15.8 17.6 10.4 21.2 17.4 17.0 14.8 14.0 10.3 20.9 20.4 24.5 15.5 10.7 24.1 20.9 13.7 19.0 34.1 7.0 25.3 8.0 9.7 7.8 8.9 17.2 11.3 7.4 6.8 19.5 10.5 27.0 15.5 7.6 10.3 4.6 6.1 6.1 4.2 4.2 5.9 5.3 5.9 6.4 5.8 5.6 6.8 21.8 12.8 20.8 24.8 26.2 9.9 11.8 12.2 9.1 23.3 18.3 10.4 17.1 5.7 18.3 16.5 47.9 15.3 27.2 29.0 27.4 19.3 49.2 15.8 21.3 20.3 30.1 9.5 30.5 21.6 14.9 15.5 19.9 13.5 23.5 17.2 20.7 25.7 22.6 23.5 27.6 22.4 10.2 21.9 13.2 10.2 13.4 24.8 10.6 33.7 26.8 27.8 24.7 38.2 38.0 24.0 27.2 15.4 12.0 15.6 20.7 22.8 20.3 111.2 13.1 20.5 16.7 14.7 13.9 10.7 12.4 13.5 16.1 19.6 23.9 20.3 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Excitatory neurons: 1.7;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Cell line enhanced" "Detected in some" "A549: 3.1;HEK 293: 1.8;HeLa: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 1.5 0.3 0.3 1.8 1.1 629.4 0.3 3.4 1.5 0.1 0.0 0.3 0.6 0.2 0.0 0.5 0.6 0.2 1.7 0.6 0.0 0.8 2.5 8.7 0.5 0.0 0.1 0.1 0.5 0.0 0.7 0.9 0.0 0.2 0.0 0.0 0.5 0.0 0.3 1.0 0.7 0.1 0.0 42.5 0.4 1.0 0.0 3.3 0.5 2.3 0.0 0.4 0.2 0.0 0.3 3.1 0.5 0.3 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.5 0.2 0.8 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.8 1.8 0.3 1.7 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.3 0.0 0.2 0.2 0.9 0.2 0.0 1.2 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.7 0.6 0.3 0.4 0.7 0.0 0.2 0.4 443.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 494.6 0.0 2.3 0.0 0.1 3.9 0.3 1.1 3.4 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PGRMC2 "DG6, PMBP" ENSG00000164040 "Progesterone receptor membrane component 2" O15173 4 128269237-128288829 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041172, HPA058652" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 76000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nuclear bodies, Plasma membrane, Cytosol" "HPA041172: AB_2677345, HPA058652: AB_2683786" "unprognostic (6.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-2)" "prognostic favorable (3.62e-4)" "unprognostic (6.03e-2)" "unprognostic (6.57e-3)" "unprognostic (2.53e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (8.24e-2)" "unprognostic (9.04e-2)" "unprognostic (3.80e-2)" "prognostic favorable (9.60e-4)" "unprognostic (3.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (6.03e-2)" 107.3 51.9 23.8 38.1 25.6 41.7 76.6 25.8 29.8 58.4 34.1 68.1 127.3 52.3 51.3 57.5 44.2 53.4 50.7 25.0 30.2 96.0 173.8 42.7 30.6 25.6 29.6 57.9 74.2 80.5 49.0 85.3 27.7 53.0 65.2 55.1 55.3 73.2 54.4 98.2 121.9 67.4 26.6 32.5 95.8 39.5 28.5 28.0 65.6 44.0 40.8 56.3 51.0 29.8 123.3 44.4 80.3 64.9 339.8 177.6 80.5 164.6 182.7 119.4 158.3 46.4 123.6 86.3 187.8 213.4 138.8 70.1 74.3 81.6 149.3 49.7 42.7 58.0 111.3 88.3 429.1 84.7 41.7 140.9 161.3 100.3 123.3 277.0 109.1 55.0 98.2 105.6 173.7 38.2 78.9 39.2 63.1 148.5 39.7 62.5 64.2 59.8 176.8 42.9 63.3 59.7 92.4 103.1 97.3 131.2 79.7 38.0 203.5 100.0 81.4 103.8 77.3 121.0 106.0 91.3 109.9 74.4 70.1 2.2 1.0 2.0 1.5 0.9 0.7 1.2 1.8 1.5 0.6 0.9 1.6 1.5 0.9 1.1 0.7 2.4 2.0 0.6 23.8 25.6 25.8 29.8 25.0 30.2 25.6 29.6 27.7 26.6 28.5 29.8 95.9 54.5 41.0 16.6 27.0 100.1 49.7 27.8 54.1 22.4 49.2 32.8 60.7 58.6 35.9 44.1 10.4 85.4 41.2 68.2 29.4 57.3 80.9 42.2 59.1 50.0 35.5 104.2 20.4 74.2 146.6 69.9 53.0 64.2 12.0 31.0 47.2 125.1 35.3 11.8 19.1 67.8 40.7 15.7 39.5 49.5 46.3 22.1 67.6 13.1 19.0 98.6 21.6 13.6 25.0 69.7 50.6 37.6 48.9 58.0 177.3 111.0 27.4 41.1 13.1 63.3 53.1 33.3 27.3 51.9 111.8 274.9 32.4 39.4 58.8 34.4 PHACTR4 "FLJ13171, PPP1R124" ENSG00000204138 "Phosphatase and actin regulator 4" Q8IZ21 1 28369582-28500364 "Predicted intracellular proteins" Neurogenesis "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 212.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028985 Approved Approved "Plasma membrane,Intermediate filaments,Cytosol" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA028985: AB_10602142" "unprognostic (1.55e-1)" "unprognostic (2.61e-2)" "unprognostic (4.50e-3)" "unprognostic (1.73e-1)" "unprognostic (5.27e-1)" "prognostic favorable (1.05e-4)" "unprognostic (9.65e-3)" "unprognostic (8.77e-2)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.94e-2)" "unprognostic (3.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.03e-2)" "unprognostic (2.26e-2)" 7.2 6.5 6.3 8.6 8.1 11.8 10.1 8.2 6.8 13.6 10.2 12.9 9.1 13.7 7.1 33.0 13.2 8.9 8.9 5.8 8.5 14.1 16.3 12.4 7.8 9.1 6.8 13.1 11.7 15.1 4.0 10.4 7.2 11.8 14.1 5.1 11.3 8.2 11.9 16.2 10.3 13.8 5.5 12.0 10.7 8.6 8.0 11.9 12.4 18.3 12.2 9.4 14.8 9.3 26.0 17.2 37.8 27.5 9.6 10.2 5.8 18.1 18.3 38.5 40.0 16.4 28.1 24.5 15.9 21.6 24.3 17.7 26.3 17.4 33.9 18.1 14.9 51.6 28.2 26.5 14.3 31.2 56.7 9.9 16.4 24.7 42.7 14.0 52.0 19.5 26.0 16.9 24.5 8.0 22.3 7.8 28.3 14.0 11.8 23.2 35.7 18.5 20.2 22.8 20.1 26.0 41.0 16.9 20.9 14.9 22.5 11.1 33.3 18.8 34.6 13.4 35.8 12.4 19.7 20.1 18.4 26.2 20.3 1.9 2.0 2.0 3.3 2.0 2.9 1.4 2.6 3.3 2.2 2.2 1.8 2.6 1.4 2.4 3.3 2.6 1.2 1.5 6.3 8.1 8.2 6.8 5.8 8.5 9.1 6.8 7.2 5.5 8.0 9.3 65.9 70.5 49.8 60.7 38.9 38.6 23.6 24.1 46.7 34.6 37.0 35.8 38.5 40.0 53.7 23.9 20.9 17.6 36.7 59.9 17.6 32.4 6.1 125.6 58.6 56.2 49.3 32.2 65.8 36.5 17.3 29.1 35.2 212.6 48.0 38.8 42.5 63.3 22.8 23.5 82.6 57.0 24.4 33.6 32.3 8.5 19.3 40.3 17.8 92.8 33.7 19.8 51.5 117.1 148.1 48.2 33.5 29.7 30.8 24.4 40.0 45.5 63.3 39.8 39.5 45.6 31.0 47.1 39.4 62.1 54.1 15.2 35.7 15.3 50.6 30.9 PHF14 KIAA0783 ENSG00000106443 "PHD finger protein 14" O94880 7 10973336-11169623 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000538, HPA017376" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Cytosol" "HPA000538: AB_1079604, HPA017376: AB_2732420" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "unprognostic (3.73e-3)" "unprognostic (7.38e-3)" "unprognostic (8.05e-2)" "unprognostic (3.38e-1)" "unprognostic (4.66e-3)" "unprognostic (1.80e-1)" "unprognostic (5.32e-3)" "unprognostic (6.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.84e-3)" "unprognostic (1.24e-1)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" "unprognostic (2.33e-1)" 9.9 8.0 17.2 8.6 15.6 5.5 13.7 17.5 26.9 9.1 12.7 9.8 8.2 13.1 7.8 8.4 8.8 9.3 5.3 17.0 16.1 10.0 11.4 8.6 9.9 16.5 16.7 14.5 7.1 9.5 7.9 8.4 17.3 10.0 10.4 6.7 7.9 8.1 6.0 8.5 8.2 11.0 14.2 10.3 10.3 9.3 16.0 17.8 9.2 7.8 10.2 9.2 7.6 16.9 16.4 32.8 46.4 49.2 16.2 15.6 23.1 12.6 10.0 14.5 15.9 29.5 28.9 62.4 22.7 11.7 32.7 22.8 42.4 14.6 16.0 23.1 17.3 31.1 28.1 38.0 14.8 70.2 28.8 14.2 15.0 17.3 30.9 20.4 21.2 24.2 42.4 21.6 17.6 21.6 28.0 30.4 39.3 68.1 24.4 45.9 30.3 19.8 15.0 30.6 42.2 58.3 19.5 64.6 21.1 33.6 34.6 50.1 20.6 20.3 27.1 13.6 25.0 27.7 51.1 43.2 14.4 57.8 48.6 1.0 0.9 0.6 1.3 0.8 1.0 1.8 1.4 1.6 0.5 1.4 1.9 1.7 0.0 1.4 0.8 2.7 1.9 0.4 17.2 15.6 17.5 26.9 17.0 16.1 16.5 16.7 17.3 14.2 16.0 16.9 80.6 41.7 41.6 141.0 66.9 57.5 68.6 27.5 68.9 92.7 80.3 91.3 22.7 37.1 44.2 33.1 58.4 68.8 58.4 54.6 27.4 92.0 23.9 40.9 82.7 77.4 92.2 46.9 223.8 84.3 80.9 65.9 55.5 48.1 56.5 103.7 64.2 43.6 42.1 79.1 260.6 72.3 42.7 39.6 24.7 16.2 102.9 39.1 37.4 116.2 58.0 36.5 87.6 263.4 200.8 90.4 45.9 116.9 34.3 82.0 46.0 35.9 28.0 63.3 52.6 71.0 67.6 142.3 133.7 56.5 52.4 39.8 58.6 73.7 72.0 54.2 PHF20 "C20orf104, dJ1121G12.1, TDRD20A" ENSG00000025293 "PHD finger protein 20" Q9BVI0 20 35771974-35950370 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 452.5;Late spermatids: 661.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029619, HPA029620, HPA029621" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear membrane, Cytosol" "HPA029619: AB_10600090, HPA029620: AB_10601110, HPA029621: AB_10602201" "unprognostic (1.21e-3)" "unprognostic (7.30e-2)" "unprognostic (3.20e-2)" "unprognostic (2.35e-3)" "unprognostic (1.36e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (2.76e-1)" "unprognostic (2.17e-1)" "unprognostic (2.64e-2)" "unprognostic (4.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.92e-2)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (7.23e-2)" "unprognostic (1.01e-2)" 12.9 8.2 10.4 12.0 11.5 11.8 12.5 15.4 13.0 10.8 9.4 10.9 6.0 11.8 7.3 11.9 9.2 10.8 11.5 11.2 10.4 7.8 8.2 10.0 14.2 11.6 11.1 13.2 6.8 12.1 5.4 11.7 11.1 10.3 8.4 14.4 9.5 10.8 32.3 8.1 7.8 11.6 9.5 14.7 8.2 11.8 11.8 14.7 10.2 17.6 13.9 10.5 8.5 14.7 18.1 14.2 24.4 36.0 17.3 19.7 22.5 20.2 19.1 19.8 17.2 41.4 13.1 30.1 17.9 27.1 24.4 10.7 22.6 28.2 24.1 13.7 9.6 55.8 26.3 15.6 17.3 27.2 20.8 15.6 38.8 21.0 32.2 23.5 22.1 21.0 23.3 18.8 23.1 10.8 27.6 15.9 12.0 11.9 17.5 20.0 35.9 17.9 15.9 12.4 21.9 17.9 36.0 41.0 18.4 21.8 32.6 20.0 31.1 43.7 9.9 23.0 21.0 17.2 22.0 21.5 32.2 19.5 22.9 17.3 11.2 33.1 12.4 11.5 13.6 15.0 12.5 14.6 10.6 11.1 14.0 14.7 25.9 16.0 16.9 9.9 7.2 9.0 10.4 11.5 15.4 13.0 11.2 10.4 11.6 11.1 11.1 9.5 11.8 14.7 51.2 38.5 41.8 28.4 131.1 34.8 76.6 52.5 31.3 77.4 49.8 53.5 62.2 31.5 43.5 38.6 98.0 106.7 191.0 16.3 37.2 29.8 452.5 39.8 41.6 46.3 36.0 37.6 49.7 19.9 52.5 53.6 23.0 34.7 142.4 41.2 47.2 18.2 54.5 114.4 49.5 27.9 30.5 62.7 84.3 661.6 35.8 87.1 39.2 62.8 62.6 50.0 105.0 34.2 55.2 24.1 26.5 53.4 76.9 60.0 14.0 24.8 50.2 80.7 19.7 65.5 50.6 60.4 47.0 29.8 28.3 22.3 127.8 30.1 28.8 55.4 PHF21B "BHC80L, FLJ34161, PHF4" ENSG00000056487 "PHD finger protein 21B" Q96EK2 22 44881162-45010005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.9" "Cell type enhanced" "Detected in some" "Astrocytes: 96.6;Cone photoreceptor cells: 22.9;Horizontal cells: 28.6;Late spermatids: 41.9;Oligodendrocyte precursor cells: 29.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 11.2;AN3-CA: 10.0;JURKAT: 8.8;SCLC-21H: 8.7;SH-SY5Y: 37.5;U-2 OS: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053834, HPA074665" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA053834: AB_2682276, HPA074665: " "unprognostic (1.04e-1)" "unprognostic (7.76e-2)" "unprognostic (2.00e-1)" "unprognostic (7.44e-2)" "unprognostic (1.37e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-3)" "unprognostic (1.86e-3)" "unprognostic (2.02e-1)" "unprognostic (9.35e-2)" "unprognostic (2.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.22e-1)" 0.2 1.2 6.7 0.1 7.9 0.0 0.4 4.8 6.1 9.0 1.5 0.2 0.1 3.2 0.4 0.4 2.5 0.1 0.9 5.1 5.1 2.6 0.0 0.1 0.0 8.5 8.3 4.0 0.5 0.9 18.9 0.0 5.2 5.2 0.0 6.1 0.3 0.5 0.2 0.1 0.2 0.7 4.4 0.1 0.6 5.4 6.8 0.2 2.0 0.3 0.0 0.2 3.2 4.7 0.0 0.0 11.2 10.0 0.0 0.0 0.7 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.1 2.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.6 0.0 0.0 8.8 0.0 0.0 0.1 0.9 1.3 0.0 6.7 0.0 0.4 0.0 2.6 0.2 0.0 0.1 8.7 37.5 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.5 8.5 0.0 0.2 0.4 0.0 5.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 7.9 4.8 6.1 5.1 5.1 8.5 8.3 5.2 4.4 6.8 4.7 0.0 0.0 0.0 96.6 0.0 0.1 0.6 0.0 0.0 14.1 0.0 0.3 2.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 1.9 0.0 16.2 0.1 3.2 0.4 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.6 0.0 0.0 0.1 28.6 9.1 0.0 0.0 0.0 0.0 41.9 0.6 0.1 0.0 5.6 0.0 5.0 0.0 29.1 9.3 0.1 0.0 1.9 0.0 1.7 0.0 0.0 0.7 23.3 0.0 1.1 0.5 1.2 2.9 0.0 0.0 0.0 0.3 1.9 0.0 0.1 PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744218 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 135.0;Exocrine glandular cells: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 25.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 975.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "CAB003681: AB_425928, CAB068216: AB_2665666, HPA021241: AB_1855299, HPA024031: AB_1855300" "unprognostic (2.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.80e-2)" "prognostic unfavorable (1.48e-4)" "prognostic favorable (1.62e-4)" "unprognostic (9.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.24e-2)" "unprognostic (4.45e-3)" "unprognostic (8.80e-3)" "unprognostic (5.00e-2)" "unprognostic (2.37e-2)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-3)" 51.4 3.0 113.6 9.4 125.3 11.4 30.1 130.7 125.9 46.1 89.1 27.2 7.6 25.4 79.6 56.6 49.3 7.6 22.4 108.8 128.8 40.9 126.0 18.0 14.9 121.8 113.9 46.1 171.1 103.9 23.7 13.2 122.4 52.6 7.0 7.5 156.2 33.5 2.6 92.5 13.3 15.0 117.0 6.5 41.7 40.3 115.8 34.0 29.5 4.3 13.3 35.8 62.9 153.6 156.8 35.2 148.0 444.6 64.9 82.8 286.1 101.0 209.3 132.9 257.6 195.7 28.6 0.1 58.1 270.5 16.6 205.6 216.8 224.6 83.9 1.1 162.1 29.1 151.3 153.3 135.7 214.3 1.7 147.6 338.6 146.8 142.2 83.0 100.1 519.7 71.4 443.9 66.8 380.9 222.8 90.1 440.0 93.3 274.6 228.0 181.1 24.8 9.6 120.4 160.8 146.0 65.9 63.9 975.9 103.9 164.8 505.7 0.9 38.3 172.1 207.3 134.8 294.0 79.9 246.1 456.9 328.2 302.7 5.3 1.1 0.2 4.7 0.3 0.2 11.1 2.4 8.2 5.3 4.0 13.0 25.2 2.2 1.8 0.3 2.6 4.5 6.3 113.6 125.3 130.7 125.9 108.8 128.8 121.8 113.9 122.4 117.0 115.8 153.6 5.3 3.2 12.6 31.6 10.0 51.9 118.1 24.2 42.7 0.7 29.7 38.0 2.1 128.7 12.5 20.2 2.1 49.9 2.2 1.6 135.0 60.2 51.2 15.6 3.8 6.9 1.8 5.5 0.3 136.1 54.0 58.7 8.6 12.2 5.7 30.9 3.6 96.1 9.2 0.0 0.6 3.6 18.3 2.2 4.3 116.9 67.7 6.5 56.9 2.8 11.0 82.4 0.0 14.1 32.3 35.6 2.0 127.9 27.4 62.1 0.2 118.4 24.7 3.4 13.1 11.2 48.8 20.0 19.4 57.5 77.1 25.3 5.9 71.4 3.2 56.8 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 159.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1438.7;Basal squamous epithelial cells: 582.8;Urothelial cells: 760.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 296.3;RPTEC TERT1: 233.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: AB_2685028" "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 21.3 31.0 9.9 17.3 10.1 21.8 28.1 8.9 11.0 23.1 6.2 8.9 6.5 13.4 4.4 59.8 7.8 39.3 20.6 10.3 11.3 14.8 67.6 27.1 5.9 10.8 16.9 19.2 17.9 5.3 8.2 14.3 11.3 8.9 10.2 13.8 159.1 8.2 5.8 11.5 8.6 14.8 9.6 19.5 22.5 3.1 11.5 7.4 27.2 1.5 7.5 60.9 33.7 11.3 60.9 71.5 54.9 30.4 25.0 51.6 3.9 50.5 134.7 22.4 30.8 39.7 72.2 0.3 14.8 21.2 73.8 30.7 1.5 84.2 47.9 9.3 1.2 1.5 3.8 68.2 36.3 1.4 15.1 16.2 60.6 93.2 182.6 296.3 54.4 0.1 5.0 1.7 115.8 7.8 0.2 7.9 20.1 36.3 108.7 0.2 14.3 1.8 233.7 135.1 4.0 10.4 8.8 0.8 169.5 67.8 35.5 0.7 50.8 75.8 7.2 89.3 50.4 0.8 0.3 0.2 127.9 0.8 96.7 0.2 0.0 0.0 0.9 0.1 1.5 0.0 0.9 1.0 0.0 0.0 0.1 0.2 0.2 0.0 1.1 0.0 1.6 0.2 9.9 10.1 8.9 11.0 10.3 11.3 10.8 16.9 11.3 9.6 11.5 11.3 98.5 12.8 12.4 7.2 13.0 195.3 1438.7 249.6 582.8 5.2 136.2 140.3 34.8 11.5 44.4 31.3 2.1 4.7 42.9 11.6 84.1 74.8 2.2 11.5 111.2 162.5 117.7 0.0 7.8 43.1 11.5 203.2 55.0 20.4 79.5 7.1 21.4 127.8 94.7 1.7 14.6 41.0 384.5 14.0 123.4 2.1 9.3 110.8 286.4 8.4 24.0 97.8 0.0 142.2 2.7 208.4 27.7 15.4 19.0 116.1 0.2 39.3 12.4 5.2 269.5 59.8 276.3 0.7 3.2 66.3 75.6 7.4 132.8 20.7 18.0 760.3 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PHLDB3 FLJ40193 ENSG00000176531 "Pleckstrin homology like domain family B member 3" Q6NSJ2 19 43474954-43504935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.0;skin 1: 43.5" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 58.0;Urothelial cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043425 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA043425: AB_10797142" "unprognostic (2.50e-2)" "unprognostic (4.22e-3)" "unprognostic (3.06e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "unprognostic (4.43e-1)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (3.60e-2)" "prognostic favorable (6.36e-6)" "unprognostic (4.62e-2)" "prognostic unfavorable (4.11e-5)" "prognostic unfavorable (5.77e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (2.37e-1)" 3.7 9.2 6.3 5.6 5.5 3.5 6.4 3.9 6.4 14.4 8.9 6.1 5.0 5.3 1.1 42.0 8.0 6.1 5.7 5.1 7.8 8.1 13.9 5.6 7.7 4.5 3.8 12.7 8.0 4.2 10.5 3.1 5.8 14.8 1.7 0.8 15.6 3.7 3.7 43.5 6.6 1.9 2.8 6.6 6.3 30.1 4.5 6.2 5.0 1.0 6.8 8.2 22.4 11.3 6.9 7.2 3.0 7.4 2.6 5.3 19.1 4.9 4.3 4.8 3.3 7.3 7.2 4.1 15.2 3.0 3.8 8.0 2.1 8.6 0.9 9.9 6.8 4.6 7.4 8.8 6.5 1.8 8.5 4.5 10.7 5.1 3.1 3.7 4.3 10.2 8.3 6.1 2.4 11.0 7.2 0.4 1.8 16.6 5.8 8.3 3.9 2.8 2.3 23.3 0.1 6.4 6.3 13.5 6.2 1.8 9.7 5.8 5.4 3.1 8.2 3.8 4.7 15.8 18.8 4.7 2.9 3.4 5.3 0.2 2.3 0.3 2.4 1.4 1.8 2.2 2.2 1.8 4.4 2.4 3.2 3.0 0.5 1.8 0.1 5.1 2.3 1.7 6.3 5.5 3.9 6.4 5.1 7.8 4.5 3.8 5.8 2.8 4.5 11.3 2.7 0.0 1.7 2.6 17.1 29.1 27.2 11.6 31.9 1.0 10.0 8.0 1.9 8.6 7.6 9.2 0.0 18.5 7.6 7.1 1.9 5.5 11.3 12.9 9.6 4.6 3.0 1.7 5.1 2.4 4.5 7.3 4.6 9.8 5.7 3.2 4.6 12.6 3.6 0.0 7.0 4.3 8.2 2.8 34.7 8.9 3.7 11.2 5.4 11.2 6.7 4.1 7.2 4.0 2.0 2.1 4.7 3.4 11.6 22.0 10.5 8.5 12.7 1.9 6.6 8.6 10.9 28.2 4.8 37.7 38.4 58.0 14.3 4.6 3.7 45.1 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.0;retina: 32.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Distal enterocytes: 75.5;Excitatory neurons: 69.5;Proximal enterocytes: 73.7;Rod photoreceptor cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 4.2 2.8 6.6 2.8 7.5 6.5 2.7 5.8 7.4 3.5 0.1 11.7 11.1 3.7 2.9 1.4 3.2 2.4 2.8 7.8 4.8 3.4 3.0 3.1 3.5 4.6 3.9 4.2 3.1 4.5 4.0 2.7 4.7 2.7 12.2 32.2 1.7 3.4 1.9 1.8 22.0 4.5 0.6 2.5 2.4 6.8 5.3 1.9 6.6 2.6 3.2 3.3 2.4 5.1 6.0 7.8 8.3 9.3 6.5 7.8 4.8 8.8 8.0 12.5 10.1 7.2 1.9 11.8 3.4 14.6 9.0 12.4 12.1 4.5 16.1 4.2 6.5 3.3 7.3 4.8 5.1 2.9 5.0 5.8 2.5 17.7 5.7 5.2 4.7 4.1 3.0 3.2 8.7 12.7 3.9 2.3 6.5 1.9 2.1 6.3 7.3 3.9 5.9 4.5 7.2 3.8 18.9 5.1 3.1 6.4 6.3 1.6 6.5 12.5 9.0 5.3 7.4 7.1 5.4 11.9 7.7 2.3 2.8 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.1 0.3 0.1 0.3 0.2 0.2 0.2 0.7 0.1 0.5 0.3 0.1 6.6 7.5 5.8 7.4 7.8 4.8 4.6 3.9 4.7 0.6 5.3 5.1 4.0 9.6 2.2 26.1 7.4 9.3 5.1 3.5 7.4 20.6 6.9 5.6 3.3 0.0 3.6 3.7 104.3 4.3 3.8 75.5 0.0 2.7 12.0 2.9 6.1 5.3 6.0 22.9 69.5 2.3 0.4 7.7 1.1 5.1 10.2 11.3 2.9 4.1 1.5 23.5 45.9 6.7 4.1 7.0 12.7 6.3 5.3 2.7 14.2 10.3 3.2 6.5 1.0 30.7 32.7 2.5 31.4 5.3 4.0 8.2 73.7 5.1 3.1 68.6 6.6 7.8 7.9 31.6 20.4 1.9 9.1 1.4 4.9 1.7 9.2 2.2 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 953.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 590000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 71.5 109.2 196.7 54.5 200.5 64.6 62.4 206.2 245.6 76.0 192.2 74.0 54.0 44.7 103.0 70.6 99.3 62.0 267.2 192.3 203.3 82.6 47.9 57.3 57.4 199.3 191.9 65.0 153.4 160.9 85.2 49.8 200.3 89.2 50.5 26.3 144.0 86.6 432.6 45.8 62.9 78.1 198.8 41.6 61.5 56.9 199.1 68.5 86.7 441.5 40.0 71.8 41.4 216.2 53.6 452.5 225.6 199.1 153.4 266.0 412.8 147.6 170.8 158.8 138.6 165.7 138.0 145.1 142.8 168.6 180.0 155.0 51.2 293.9 50.2 116.9 132.5 45.4 276.8 380.3 177.5 82.6 176.4 322.8 248.7 91.8 109.5 145.8 218.8 93.1 102.9 129.7 257.2 328.2 156.9 176.7 216.0 372.5 206.6 106.5 106.6 196.7 255.6 113.3 137.6 132.8 146.7 155.8 75.1 107.0 127.2 226.4 177.0 390.6 130.8 91.5 166.5 60.5 93.4 94.0 174.3 59.7 235.8 38.2 290.0 31.0 197.6 318.4 170.7 241.3 173.9 184.6 321.8 178.9 126.0 175.8 13.7 196.7 231.7 425.4 223.6 324.1 196.7 200.5 206.2 245.6 192.3 203.3 199.3 191.9 200.3 198.8 199.1 216.2 125.7 96.1 159.8 24.8 111.8 150.3 187.7 659.2 204.9 43.9 223.1 317.7 384.8 178.7 326.5 217.0 22.9 322.1 111.8 337.1 747.4 196.1 271.3 122.2 168.1 111.9 265.1 80.2 8.1 252.4 489.5 213.1 140.6 170.3 123.5 367.4 83.6 201.9 286.5 67.3 12.5 370.9 309.3 97.2 197.1 953.5 205.0 133.6 334.4 5.6 273.2 194.7 146.2 10.6 25.0 185.3 359.8 223.4 187.8 257.5 540.1 817.4 250.6 77.7 85.5 137.1 249.6 141.8 143.8 140.3 161.8 264.1 106.4 352.5 336.0 199.5 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 78.9;Late spermatids: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: AB_2684508" "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favorable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.3 23.9 7.1 3.8 8.0 30.4 15.0 2.0 12.0 15.4 8.6 16.2 7.5 18.3 1.4 13.2 16.5 2.8 13.3 9.6 5.2 30.7 19.0 17.9 2.5 6.6 9.7 15.6 21.9 9.4 25.4 3.3 6.5 19.4 1.1 1.2 19.3 5.8 18.4 15.7 12.6 1.6 3.5 15.0 17.0 28.1 6.0 2.7 31.1 1.7 1.2 15.8 12.1 4.3 14.2 21.9 7.3 10.3 4.6 2.7 13.9 14.7 5.6 6.3 6.6 14.6 12.9 7.6 18.6 3.3 5.5 22.2 3.3 6.4 1.3 21.9 30.4 11.4 23.8 10.8 8.9 10.1 10.2 5.2 9.8 10.2 2.0 4.0 6.1 13.7 26.1 4.1 2.1 20.7 18.3 11.4 10.0 3.0 21.9 36.6 6.4 17.7 5.6 5.6 13.2 21.4 16.8 7.6 10.8 2.3 17.3 6.9 14.5 10.4 13.7 11.7 10.4 15.8 5.0 6.0 4.8 5.4 10.4 0.9 2.8 1.6 2.8 3.1 2.4 2.3 2.3 2.6 2.7 2.5 2.5 1.6 3.0 3.3 3.7 5.6 2.4 2.6 7.1 8.0 2.0 12.0 9.6 5.2 6.6 9.7 6.5 3.5 6.0 4.3 9.7 16.0 20.3 14.0 6.9 4.8 6.6 8.4 5.2 12.1 15.8 11.0 8.4 4.3 10.6 40.5 4.2 10.5 8.8 31.5 3.9 19.3 33.6 21.0 7.8 9.0 20.3 78.9 19.3 17.4 8.4 9.4 16.3 11.4 8.2 19.7 6.4 16.4 9.5 10.1 13.8 13.0 8.2 9.1 4.4 61.4 7.5 8.2 16.0 3.7 7.7 14.6 10.3 7.5 6.6 14.1 11.6 7.2 9.1 6.9 7.6 12.4 23.3 13.7 0.0 7.7 9.9 30.1 13.6 6.2 4.8 5.9 7.8 11.1 16.9 5.0 PIGX FLJ20522 ENSG00000163964 "Phosphatidylinositol glycan anchor biosynthesis class X" Q8TBF5 3 196639775-196736007 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 87.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 87.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029409, HPA073301" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029409: AB_10610280, HPA073301: " "unprognostic (8.83e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.14e-1)" "unprognostic (2.42e-3)" "unprognostic (9.25e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (1.91e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.02e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.01e-1)" 10.5 10.3 14.4 10.4 15.6 9.0 9.9 14.7 16.7 7.5 19.5 10.8 9.1 8.3 12.4 10.3 7.9 8.3 9.6 15.2 16.7 12.2 8.2 7.2 7.1 15.1 15.8 6.8 9.0 19.6 12.7 8.3 14.8 12.8 10.1 17.4 9.9 10.5 17.1 10.4 9.1 11.2 16.0 6.8 7.6 6.0 16.2 11.6 9.2 14.1 10.9 8.7 7.6 16.7 39.4 18.7 21.4 18.1 22.7 15.3 12.6 18.1 20.7 19.3 20.5 13.7 25.6 20.3 63.6 15.4 25.1 22.2 19.5 16.6 23.1 18.6 19.6 21.0 12.8 12.6 19.2 20.6 34.6 15.1 25.7 17.1 15.7 16.3 12.7 36.5 11.7 38.6 21.0 30.1 59.2 32.1 12.8 30.7 18.3 31.1 27.6 29.5 24.6 11.5 24.4 29.2 31.8 23.9 29.7 16.9 71.8 20.3 8.2 18.1 9.2 25.6 29.5 57.0 70.4 41.1 20.7 26.9 21.5 39.6 7.5 87.5 3.3 10.8 3.0 4.6 3.1 4.6 7.7 5.5 3.7 3.2 18.8 8.7 11.6 3.3 4.4 4.1 14.4 15.6 14.7 16.7 15.2 16.7 15.1 15.8 14.8 16.0 16.2 16.7 14.2 19.2 16.3 13.7 16.4 17.1 30.1 5.5 31.9 34.9 28.3 19.2 12.6 21.5 8.4 29.5 47.9 21.4 31.6 20.8 35.2 7.9 30.5 17.2 23.5 16.9 15.7 15.8 17.7 5.6 20.9 22.0 9.2 17.9 12.0 19.3 17.5 16.6 20.1 33.7 23.7 17.0 8.2 21.4 25.4 22.7 28.0 18.1 21.4 15.9 25.0 50.0 32.0 12.1 14.5 5.2 12.5 35.0 20.1 33.8 27.1 32.5 10.2 39.1 26.3 23.6 28.1 27.1 36.0 29.3 15.9 11.6 21.2 22.7 25.7 23.0 PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Hepatocytes: 70.7;Kupffer cells: 127.0;Macrophages: 89.8;Microglial cells: 60.9;monocytes: 57.4;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cell line enhanced" "Detected in many" "Daudi: 85.3;NB-4: 62.1;REH: 183.5;THP-1: 92.9;U-698: 114.7;U-937: 95.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" 8.1 4.5 2.1 51.1 2.0 47.5 4.7 2.4 3.2 2.8 2.7 7.3 6.8 2.1 1.7 2.4 2.2 24.8 2.5 1.9 2.9 11.8 83.2 16.7 61.2 6.5 4.6 6.0 22.8 2.0 1.4 14.1 5.3 2.8 8.6 3.1 73.6 2.4 0.7 1.0 7.7 8.3 4.7 62.3 6.9 3.0 5.7 8.7 4.1 3.1 57.8 15.2 0.6 7.6 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.9 1.2 2.8 1.5 85.3 8.5 0.0 1.3 0.1 17.7 0.0 0.6 48.0 3.0 13.0 0.0 1.7 0.1 36.1 6.7 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.9 0.1 0.1 0.4 1.1 62.1 0.8 24.3 1.0 183.5 4.3 20.0 0.2 0.1 3.6 2.0 0.2 0.2 1.1 0.3 0.2 92.9 0.0 0.0 2.8 0.1 0.7 0.7 0.2 114.7 0.0 95.2 0.0 6.1 16.0 10.5 13.3 44.7 4.7 48.3 0.3 4.1 12.9 44.5 0.1 3.3 13.5 14.0 123.0 11.3 0.5 14.4 2.1 2.0 2.4 3.2 1.9 2.9 6.5 4.6 5.3 4.7 5.7 7.6 0.5 3.2 3.9 1.3 53.7 1.5 0.1 0.1 0.6 0.6 2.2 2.3 2.6 32.9 2.2 1.8 2.1 0.5 41.5 8.1 1.9 40.0 4.3 0.3 0.1 1.8 1.8 10.3 0.8 29.1 0.9 0.7 0.0 0.2 14.0 0.2 5.7 70.7 47.7 0.0 0.8 2.8 4.1 127.0 32.5 1.0 1.2 89.8 5.4 60.9 57.4 0.2 58.7 1.0 0.3 16.4 21.2 2.2 9.4 0.4 1.6 18.3 1.1 3.4 0.0 0.6 0.8 0.8 0.2 0.3 1.1 2.3 18.3 0.4 3.8 0.3 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Vesicles, Cytosol" "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.5 13.7 16.3 12.3 25.9 9.4 15.9 22.5 14.6 16.1 17.4 13.2 14.9 18.0 15.7 15.4 14.5 19.0 12.4 10.5 14.0 23.5 15.5 16.6 11.3 16.6 16.1 14.1 12.3 43.6 10.3 23.1 17.0 16.4 13.0 22.4 11.8 14.8 6.4 12.3 11.8 18.3 13.8 13.0 18.0 19.3 19.6 9.4 30.7 12.1 10.9 14.9 12.0 15.8 53.8 24.1 39.6 24.8 28.0 28.3 35.3 33.2 35.7 23.9 33.2 58.9 6.0 15.6 16.2 28.6 39.1 34.8 31.9 25.4 42.1 13.5 27.6 9.8 28.4 23.3 30.6 12.3 14.9 22.2 17.5 23.6 45.8 22.2 57.7 9.9 23.4 14.7 18.6 16.6 6.6 7.7 22.6 30.1 18.5 6.9 41.1 11.0 29.6 47.0 23.2 20.5 50.6 21.4 23.2 33.0 12.7 12.3 72.5 19.1 27.4 50.1 20.4 5.9 14.1 12.8 22.8 11.3 22.6 1.7 1.5 1.1 1.7 1.0 1.1 1.4 1.3 1.3 2.1 1.5 1.7 1.0 2.3 1.8 3.2 1.4 0.9 0.6 16.3 25.9 22.5 14.6 10.5 14.0 16.6 16.1 17.0 13.8 19.6 15.8 93.2 76.9 62.0 217.4 25.0 35.3 26.1 18.7 24.5 49.1 34.7 25.0 29.7 25.8 33.1 36.8 70.9 29.6 29.5 22.6 19.6 19.8 35.9 51.8 35.1 87.6 28.7 11.2 57.0 25.1 17.9 28.6 45.3 72.4 32.2 22.8 106.7 32.4 19.2 35.3 81.1 23.5 18.3 46.3 33.1 18.6 25.7 27.0 19.6 69.3 19.6 73.0 17.5 62.8 79.4 26.1 13.1 31.2 29.9 42.7 15.2 22.4 26.4 40.4 39.5 33.7 35.1 52.6 26.8 23.5 34.0 143.5 25.3 25.1 20.7 37.3 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIK3R6 "C17orf38, FLJ34500, HsT41028, p87PIKAP" ENSG00000276231 "Phosphoinositide-3-kinase regulatory subunit 6" Q5UE93 17 8802722-8867677 "Metabolic proteins, Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 11.5;granulocytes: 47.4;Hofbauer cells: 7.6;Late spermatids: 20.6;Microglial cells: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 21.9;eosinophil: 75.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 75.8" "Cell line enriched" "Detected in some" 8 "HMC-1: 148.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023077 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA023077: AB_1854909" "unprognostic (4.29e-2)" "unprognostic (8.56e-3)" "unprognostic (9.39e-2)" "unprognostic (5.96e-3)" "unprognostic (2.46e-1)" "unprognostic (5.25e-3)" "unprognostic (4.50e-3)" "unprognostic (2.29e-2)" "unprognostic (3.12e-2)" "unprognostic (3.14e-1)" "unprognostic (2.20e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.50e-6)" "unprognostic (3.45e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-1)" "unprognostic (8.98e-2)" 0.4 0.0 1.1 1.8 1.6 2.2 0.4 0.9 1.1 0.6 0.8 0.8 1.5 0.9 0.1 0.5 0.2 1.2 1.3 1.0 1.1 0.0 0.3 1.2 2.1 1.4 1.5 0.0 0.4 0.1 0.0 0.6 1.6 0.3 0.6 0.0 0.2 0.3 0.5 0.8 2.2 0.7 1.1 2.9 1.0 0.4 1.9 2.1 0.0 0.3 1.5 1.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 14.1 0.0 19.4 0.0 0.0 0.0 0.0 148.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 2.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 21.9 7.2 75.8 0.5 9.6 0.4 2.7 0.1 0.3 10.8 0.3 0.1 0.2 1.1 1.5 7.8 0.0 0.0 3.3 1.1 1.6 0.9 1.1 1.0 1.1 1.4 1.5 1.6 1.1 1.9 1.6 0.2 0.0 1.3 0.3 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 11.5 0.0 0.1 2.6 0.0 0.4 0.6 0.0 0.1 0.2 0.5 0.0 47.4 0.0 0.4 0.0 7.6 0.0 0.5 0.0 0.0 4.4 1.6 20.6 0.0 3.9 1.8 7.5 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 1.6 0.1 0.0 0.0 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170152-37175428 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 219.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 368.2;Suprabasal keratinocytes: 228.6;Urothelial cells: 455.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 321.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 321.3" "Cell line enhanced" "Detected in all" "HEL: 219.9;HMC-1: 391.5;K-562: 192.7;U-698: 735.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Nucleoplasm, Nucleoli" "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 152.8 14.4 8.5 42.3 8.6 219.0 46.2 10.5 10.7 82.9 10.0 45.8 39.2 46.3 2.6 201.5 66.4 52.6 65.4 7.9 11.6 27.0 58.0 49.8 38.5 15.1 12.2 60.4 20.4 3.4 14.8 28.9 12.8 22.5 17.8 8.2 41.1 7.5 36.3 109.8 44.4 38.1 12.3 61.7 40.3 10.7 11.6 26.6 22.7 5.8 26.8 101.6 113.3 12.1 19.1 7.9 12.1 6.7 27.2 14.5 141.9 6.7 20.3 13.5 21.5 28.3 26.2 38.3 10.4 8.0 30.2 21.7 12.7 20.1 12.3 174.4 8.4 219.9 8.7 37.0 27.9 3.8 391.5 49.0 24.5 12.4 8.3 14.9 4.0 9.2 192.7 59.7 2.2 5.0 12.3 19.9 22.7 35.4 12.1 29.7 22.0 45.7 3.9 114.4 58.8 11.9 14.7 1.7 3.8 27.9 3.2 6.5 7.4 7.8 23.3 35.6 8.5 28.0 15.9 735.7 3.4 55.3 8.1 321.3 8.0 113.5 60.3 7.3 77.7 7.1 53.4 53.8 6.3 5.2 47.1 36.9 61.7 39.8 4.2 1.9 41.3 42.1 8.5 8.6 10.5 10.7 7.9 11.6 15.1 12.2 12.8 12.3 11.6 12.1 41.1 22.4 16.0 2.9 35.1 127.8 166.5 63.3 26.7 4.9 9.6 5.3 36.0 18.6 37.6 9.2 0.0 36.5 55.0 50.4 5.9 40.6 4.8 40.3 125.8 33.3 37.1 368.2 2.4 17.2 121.8 67.4 26.0 92.0 49.3 27.5 11.0 33.8 53.6 15.2 2.2 12.4 44.7 44.3 47.4 12.4 8.1 53.9 44.4 4.7 72.3 7.6 112.3 1.0 0.9 60.7 34.2 3.0 190.1 109.6 51.1 17.2 12.9 1.7 0.0 34.2 41.3 14.5 33.9 92.8 228.6 80.7 118.0 1.1 7.8 455.2 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: AB_2682503, HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favorable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favorable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favorable (2.66e-4)" 14.1 14.8 23.5 10.4 24.0 8.7 16.9 25.2 36.3 15.2 24.0 16.2 11.5 14.7 21.5 14.4 12.9 7.3 19.0 23.6 24.8 19.7 28.6 10.6 10.5 24.4 24.2 16.1 13.1 20.4 13.9 11.8 24.2 15.6 12.7 18.3 16.1 10.1 19.4 10.6 12.7 10.8 24.0 13.9 15.8 5.7 23.8 17.5 16.5 20.4 11.1 13.2 14.9 25.4 36.8 41.2 42.5 29.9 28.1 23.4 23.1 24.6 26.8 28.7 29.1 20.8 26.4 11.2 68.6 25.2 39.2 25.8 38.6 43.0 35.6 26.9 83.3 18.8 51.1 55.3 14.9 29.9 14.8 15.7 22.5 32.0 11.1 32.4 29.1 32.5 32.1 46.6 20.4 43.4 25.3 49.9 30.3 42.4 36.7 25.8 34.7 32.3 37.1 24.7 27.0 48.1 28.5 13.3 27.0 32.0 20.3 25.9 30.7 13.4 19.9 36.8 17.7 15.4 18.5 17.9 38.5 28.3 14.7 42.7 37.1 40.6 41.8 41.1 41.7 49.2 43.7 40.3 38.0 45.6 44.1 44.8 15.7 41.1 39.4 44.6 58.1 39.6 23.5 24.0 25.2 36.3 23.6 24.8 24.4 24.2 24.2 24.0 23.8 25.4 68.3 67.3 48.2 14.0 44.4 43.2 63.3 167.9 36.5 26.7 67.2 94.5 84.9 78.6 89.4 119.5 8.4 162.8 44.5 99.2 181.9 125.0 13.5 78.6 66.7 71.5 92.7 71.7 17.8 117.9 89.0 59.9 45.3 56.6 57.6 46.3 92.4 288.5 110.3 28.6 17.8 93.7 128.1 72.9 44.9 9.3 74.6 50.7 60.5 7.5 69.6 90.7 80.3 16.6 27.3 136.3 114.9 81.3 38.7 51.5 162.0 296.1 95.9 42.9 85.5 65.9 94.6 19.6 42.6 51.3 46.9 120.7 44.8 53.9 88.5 54.8 PINX1 "FLJ20565, Gno1, LPTL, LPTS, MGC8850, Pxr1" ENSG00000254093 "PIN2 (TERF1) interacting telomerase inhibitor 1" Q96BK5 8 10764961-10839884 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 20.0;Extravillous trophoblasts: 13.0;Hofbauer cells: 16.1;Syncytiotrophoblasts: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023139, HPA023146" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoli "Nucleoplasm, Mitochondria" "HPA023139: AB_1855384, HPA023146: " "unprognostic (4.01e-1)" "prognostic favorable (2.45e-5)" "unprognostic (7.80e-3)" "unprognostic (3.35e-2)" "unprognostic (4.10e-1)" "unprognostic (4.61e-2)" "unprognostic (1.83e-2)" "unprognostic (3.40e-2)" "unprognostic (9.73e-3)" "unprognostic (2.49e-1)" "unprognostic (1.40e-1)" "unprognostic (4.37e-1)" "unprognostic (2.59e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" 9.9 7.7 7.2 8.9 8.4 9.1 9.9 8.9 8.9 9.7 6.1 9.9 6.2 9.3 4.5 12.1 8.8 4.0 8.2 7.4 7.1 11.6 11.7 8.0 11.5 7.2 7.1 9.8 9.0 6.1 6.4 7.2 7.4 8.1 6.1 12.0 7.3 4.2 13.5 14.4 7.7 8.5 7.0 9.3 8.2 9.7 7.4 13.0 8.2 9.3 11.1 10.2 10.5 7.7 14.5 18.9 20.1 19.2 16.6 13.5 23.1 21.5 9.7 23.2 15.6 20.0 12.4 38.5 7.4 11.7 28.3 28.6 51.4 39.9 29.8 15.7 15.3 16.2 13.3 22.0 18.8 17.4 9.7 11.3 24.9 18.3 34.0 8.2 32.7 25.8 52.3 23.1 22.9 17.1 57.7 21.8 46.3 62.6 21.0 46.5 24.5 35.2 17.5 17.5 16.6 17.3 14.5 17.0 48.3 24.3 18.1 21.7 20.0 13.9 30.3 18.0 28.1 10.3 29.0 71.2 14.4 32.6 32.1 1.9 8.4 6.1 14.6 10.7 18.9 12.9 12.8 15.6 11.1 10.8 17.1 13.5 0.5 12.5 9.9 8.6 16.1 10.4 7.2 8.4 8.9 8.9 7.4 7.1 7.2 7.1 7.4 7.0 7.4 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 13.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 48.2 0.0 0.0 0.0 0.0 PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534854-22714578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 498.1" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1585.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 4900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: AB_2685490, HPA068771: AB_2686030" "unprognostic (1.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.57e-3)" "unprognostic (4.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.80e-3)" "unprognostic (1.56e-3)" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (7.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.52e-3)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.92e-3)" 28.4 15.5 162.5 47.8 329.4 44.8 15.0 239.0 239.9 26.5 49.8 17.8 13.2 21.1 11.8 19.8 15.2 32.9 13.5 169.7 193.6 16.5 18.6 25.9 81.2 260.6 273.4 8.8 10.9 24.8 8.5 23.7 271.7 9.3 19.1 15.3 7.8 13.0 5.1 8.3 20.6 31.5 171.8 62.6 19.3 12.5 233.3 60.4 12.8 10.9 88.5 24.1 10.5 498.1 30.2 29.2 33.4 10.8 52.3 70.6 25.3 55.0 58.1 29.1 35.7 27.6 47.2 63.2 19.4 111.0 63.7 10.4 29.2 15.4 29.2 140.5 30.4 118.7 21.6 60.9 92.5 23.1 89.1 35.6 13.7 39.7 38.2 44.6 43.7 83.5 67.4 119.1 54.5 12.5 92.3 20.5 13.7 14.5 20.7 36.9 47.8 86.3 43.0 5.8 6.1 13.9 17.7 9.0 86.4 37.6 7.6 39.1 53.0 22.3 32.8 41.7 33.9 75.1 46.3 45.0 60.5 68.3 17.6 72.6 32.6 104.0 119.5 57.9 164.0 52.1 94.2 139.9 43.7 33.1 62.8 118.2 40.5 144.2 67.3 44.8 75.9 183.4 162.5 329.4 239.0 239.9 169.7 193.6 260.6 273.4 271.7 171.8 233.3 498.1 22.5 3.2 6.7 84.9 43.2 17.6 4.0 2.0 3.4 5.7 12.9 5.5 8.1 14.3 5.6 18.4 2.1 8.6 196.9 3.4 11.7 9.7 22.9 7.4 15.7 29.2 4.9 236.9 65.6 10.7 5.4 19.6 6.6 24.8 22.8 13.4 62.4 8.7 31.8 13.5 62.0 2.9 0.0 98.6 80.0 34.5 16.8 82.8 104.9 142.4 81.3 5.0 159.6 167.9 1585.0 22.1 3.7 10.1 36.4 7.1 1.0 15.6 2.2 9.1 19.7 14.1 30.6 6.1 7.9 3.3 16.9 12.4 130.7 8.5 2.8 6.6 PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028658 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Nucleoplasm, Plasma membrane" "HPA028658: AB_10601245" "unprognostic (7.84e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (3.17e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.06e-6)" "unprognostic (1.87e-1)" "unprognostic (2.16e-1)" "unprognostic (3.27e-1)" "unprognostic (3.42e-1)" 13.6 17.2 18.4 11.6 24.0 26.5 20.0 13.4 32.8 18.4 20.7 24.1 16.0 18.5 81.6 28.2 26.6 16.1 15.0 22.3 11.5 36.0 14.8 19.7 13.5 14.9 13.0 16.0 21.0 39.1 18.7 12.1 16.0 21.6 26.3 29.1 25.6 18.4 14.0 27.1 19.2 15.9 11.9 14.6 39.8 28.1 15.7 11.4 22.4 10.5 18.8 18.2 20.5 20.9 52.0 36.4 14.8 17.6 0.0 0.1 47.0 21.4 40.6 38.7 35.1 46.7 73.4 11.3 44.1 25.6 47.4 46.1 24.2 42.2 30.3 15.9 26.1 20.0 17.5 33.7 32.8 19.3 35.0 12.9 70.0 14.7 26.9 46.4 19.6 12.1 26.8 33.3 20.0 52.6 16.5 16.7 28.1 32.1 31.2 0.5 130.9 17.2 39.6 91.1 23.7 30.0 45.8 30.4 29.7 49.3 83.2 17.8 4.2 18.5 26.1 27.7 22.8 25.1 31.5 25.6 36.0 16.0 32.1 58.8 8.2 25.8 24.3 10.5 16.1 8.7 14.8 18.4 8.6 11.0 13.8 16.7 16.3 16.2 14.6 3.8 19.9 11.0 18.4 24.0 13.4 32.8 22.3 11.5 14.9 13.0 16.0 11.9 15.7 20.9 4.1 9.6 8.6 4.9 6.9 12.4 6.2 11.7 10.8 14.3 13.2 8.0 121.7 12.8 11.9 35.0 18.8 11.3 7.4 33.7 21.5 17.7 25.7 14.2 4.2 8.8 22.2 5.2 28.0 19.7 15.2 5.4 26.0 20.3 3.8 4.0 9.3 12.6 8.9 8.4 11.8 18.4 10.2 6.0 2.2 47.9 6.8 5.7 12.4 2.8 5.9 7.5 5.2 5.0 11.5 40.5 12.8 5.3 9.4 10.1 14.2 13.3 15.3 8.1 19.7 3.8 13.1 12.0 9.0 14.3 12.8 17.4 11.9 5.5 10.4 9.2 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 20.1 19.1 16.0 16.1 17.3 9.7 19.5 17.8 19.2 18.9 20.8 17.2 16.2 18.8 21.1 20.4 18.9 19.7 19.8 16.8 17.3 21.9 18.6 21.8 18.7 15.1 15.7 18.7 13.6 23.0 21.5 25.9 14.7 16.7 15.1 30.1 16.9 14.1 29.2 21.0 16.9 20.3 14.2 19.0 16.6 35.1 16.9 24.7 18.4 25.4 20.1 20.5 17.4 18.4 49.3 37.4 57.7 67.6 37.5 38.8 56.7 63.5 89.3 116.6 103.7 68.7 46.8 43.9 66.8 67.9 52.7 42.0 75.7 42.6 101.2 68.8 54.0 36.0 48.4 33.9 70.1 64.9 43.8 51.1 40.3 72.7 90.7 52.1 48.8 69.4 35.6 36.7 60.4 69.9 63.6 32.4 86.0 38.2 58.3 60.5 50.7 34.1 61.2 27.1 38.6 49.4 87.1 66.6 57.4 96.4 69.2 59.4 47.4 46.6 64.7 42.6 77.0 50.5 93.6 99.3 44.7 18.6 56.6 0.1 3.9 5.7 3.7 4.7 2.8 6.6 3.3 4.1 6.4 3.0 3.7 2.9 8.9 3.9 3.8 6.7 3.1 4.7 16.0 17.3 17.8 19.2 16.8 17.3 15.1 15.7 14.7 14.2 16.9 18.4 11.6 32.1 12.2 43.8 21.3 66.2 23.2 17.0 39.9 34.1 31.3 22.0 18.4 17.2 15.3 31.3 98.0 25.9 18.3 12.7 9.8 13.5 4.9 64.0 26.2 15.6 6.0 12.4 59.6 8.7 29.3 19.8 19.4 71.0 12.0 19.9 14.3 14.3 12.8 26.9 51.2 9.7 18.3 10.7 29.5 4.8 13.4 14.9 12.4 44.0 12.2 12.5 9.2 54.8 64.0 19.4 8.9 10.9 16.8 20.9 21.0 10.1 18.4 43.0 13.1 17.4 20.9 52.1 24.6 38.4 50.0 63.5 15.9 18.4 10.7 39.4 PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.8;lymphoid tissue: 7.9;retina: 13.3" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Hofbauer cells: 13.6;Horizontal cells: 60.6;Kupffer cells: 14.4;Late spermatids: 20.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" 0.2 0.1 5.4 0.4 5.6 0.9 0.7 4.8 10.8 0.1 4.8 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.4 4.9 0.3 1.6 2.3 1.5 4.9 5.2 0.1 0.1 0.0 0.1 0.5 5.1 0.3 1.2 13.3 0.1 0.0 0.1 0.0 0.6 0.0 5.0 7.9 0.0 2.3 5.0 0.9 0.0 0.0 1.7 0.2 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.1 5.4 5.6 4.8 10.8 5.4 4.9 4.9 5.2 5.1 5.0 5.0 5.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 2.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 13.6 60.6 0.4 0.0 0.0 14.4 0.0 20.1 0.3 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLAA "DOA1, FLJ11281, FLJ12699, PLA2P, PLAP" ENSG00000137055 "Phospholipase A2 activating protein" Q9Y263 9 26903372-26947242 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005035, HPA020994, HPA020996" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 12000000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB005035: AB_562036, HPA020994: AB_1855444, HPA020996: AB_1855445" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (4.00e-3)" "unprognostic (5.00e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (4.50e-3)" "unprognostic (2.48e-1)" "unprognostic (5.54e-2)" "prognostic favorable (7.87e-4)" "unprognostic (3.24e-2)" "unprognostic (1.44e-1)" "unprognostic (9.29e-3)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.39e-2)" "unprognostic (5.10e-1)" 16.0 16.9 8.5 16.2 9.0 42.0 12.6 9.3 11.2 11.3 9.6 15.2 13.6 17.5 13.4 18.8 9.8 13.0 18.8 9.5 9.7 15.4 21.5 12.8 15.0 8.1 8.3 11.0 12.0 16.9 8.0 16.0 9.0 12.9 15.9 14.1 10.9 12.5 50.3 12.1 12.6 19.3 8.3 13.3 12.7 20.4 8.1 18.0 15.9 29.1 18.1 14.7 11.2 10.2 64.6 37.0 46.1 46.3 30.4 38.2 34.6 58.4 33.1 43.9 42.2 13.1 29.8 56.9 48.0 45.0 30.6 25.1 45.8 46.0 47.7 75.7 19.1 35.2 57.9 25.5 30.9 28.8 46.3 34.4 27.0 53.2 38.8 33.0 44.3 41.7 22.1 56.6 47.6 26.6 56.3 28.1 66.8 33.2 31.6 39.4 28.7 34.4 33.5 37.6 29.2 49.9 31.3 36.5 19.1 44.8 25.5 22.5 54.3 0.2 53.8 28.5 48.3 18.4 43.7 59.5 30.8 40.4 23.4 21.9 12.7 21.0 11.0 18.2 12.6 14.3 11.5 11.4 13.1 11.9 10.3 12.0 11.4 14.9 21.2 6.6 18.0 9.6 8.5 9.0 9.3 11.2 9.5 9.7 8.1 8.3 9.0 8.3 8.1 10.2 10.8 16.0 11.2 18.3 18.8 11.0 11.3 14.6 17.1 9.1 7.5 6.6 23.8 5.7 16.1 9.2 0.0 24.9 14.9 11.9 9.8 17.6 27.7 10.2 12.3 17.1 9.6 25.9 31.9 16.2 26.6 11.5 15.8 14.7 40.6 13.2 12.5 10.7 20.7 5.0 30.8 8.6 14.2 15.8 8.2 6.6 8.7 17.5 1.8 21.5 15.9 9.5 16.5 24.6 32.1 15.2 8.7 8.2 23.1 10.6 11.0 12.3 12.7 6.7 19.7 13.0 34.1 28.1 24.9 20.9 9.5 49.3 18.3 21.5 12.6 11.6 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 252.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.6;Leydig cells: 138.5;Theca cells: 205.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 99.0;RH-30: 94.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: AB_2682893" "unprognostic (4.74e-3)" "unprognostic (8.35e-3)" "unprognostic (5.43e-2)" "unprognostic (1.74e-3)" "unprognostic (5.09e-2)" "unprognostic (1.95e-1)" "unprognostic (9.32e-2)" "unprognostic (6.17e-2)" "unprognostic (3.49e-2)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.94e-6)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.69e-2)" "unprognostic (5.17e-3)" "unprognostic (4.93e-3)" 37.7 74.8 4.1 18.5 5.2 21.7 29.6 1.9 7.0 31.4 5.8 28.8 9.6 29.5 9.0 32.9 20.8 26.9 26.4 3.8 2.9 17.0 3.6 26.7 12.1 3.6 4.1 36.5 27.7 9.5 81.6 252.3 3.9 26.0 21.3 1.6 30.1 12.1 12.2 61.9 20.6 19.7 3.2 15.6 26.9 8.7 6.0 6.6 13.8 22.3 12.1 39.6 34.4 4.0 0.2 5.0 99.0 0.1 39.4 78.0 0.3 32.9 21.6 16.1 33.5 0.3 6.0 2.7 16.0 30.4 4.0 0.0 0.8 12.0 32.2 3.1 4.4 45.2 58.7 0.9 13.9 40.9 8.9 60.5 4.6 15.8 13.8 23.4 33.5 16.1 4.4 0.8 18.0 6.2 16.9 19.8 17.2 0.0 3.7 20.7 94.1 0.1 33.1 1.1 8.7 10.3 51.0 0.1 0.1 29.6 0.1 50.1 19.8 0.2 35.2 77.7 36.4 9.1 9.0 0.6 25.3 16.6 2.0 4.9 12.0 25.1 1.4 9.1 1.4 3.7 1.3 1.9 14.9 5.8 0.9 1.5 21.7 2.2 2.9 6.7 2.0 3.8 4.1 5.2 1.9 7.0 3.8 2.9 3.6 4.1 3.9 3.2 6.0 4.0 19.5 51.3 51.0 28.4 15.2 21.7 14.6 5.3 34.1 2.1 16.8 14.0 8.4 5.7 12.6 5.5 0.0 4.6 19.0 16.1 7.9 11.8 1.8 8.6 91.9 23.8 16.7 19.3 60.3 11.3 15.0 143.6 11.7 13.0 18.4 38.7 8.6 0.2 20.3 8.4 76.6 33.6 18.3 26.8 27.8 5.5 138.5 26.8 8.8 49.6 37.6 0.9 2.1 10.6 5.5 13.0 22.5 97.0 5.7 52.0 4.3 15.3 4.4 0.4 13.1 61.7 31.1 0.9 1.0 24.1 43.3 9.9 10.0 205.8 28.5 19.7 PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607855-218637184 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 166.0;skeletal muscle: 114.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 139.9;Cone photoreceptor cells: 246.0;Rod photoreceptor cells: 176.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SH-SY5Y: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009914, HPA038139, HPA038140" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Endoplasmic reticulum, Plasma membrane" "CAB009914: AB_2252306, HPA038139: AB_2675855, HPA038140: AB_2675856" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (5.65e-5)" "unprognostic (7.77e-2)" "unprognostic (1.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.86e-2)" "unprognostic (3.15e-1)" "unprognostic (8.87e-3)" "unprognostic (7.54e-5)" "unprognostic (3.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (6.32e-2)" "unprognostic (8.46e-3)" "unprognostic (3.09e-1)" 1.5 2.7 4.5 0.2 4.4 0.0 1.3 4.5 7.2 1.4 3.5 15.6 0.6 0.6 0.3 4.8 0.6 0.4 1.1 4.5 4.6 10.7 0.6 0.6 0.1 5.6 5.1 0.7 0.5 1.7 9.6 0.2 4.9 4.4 1.7 166.0 2.3 0.3 114.0 1.0 3.3 1.3 4.2 0.3 6.9 9.8 5.0 0.1 1.6 30.4 0.1 20.5 2.0 4.7 0.0 0.9 1.2 0.0 0.3 1.2 1.1 0.0 2.5 0.4 1.3 0.0 0.1 0.0 1.5 0.4 0.4 0.1 0.0 1.5 0.3 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 2.8 0.1 1.9 0.5 4.2 2.8 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.1 4.3 0.0 1.8 20.2 0.3 0.1 0.1 0.2 2.1 0.0 4.5 0.1 0.0 0.2 0.2 0.0 0.0 0.0 4.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 4.4 4.5 7.2 4.5 4.6 5.6 5.1 4.9 4.2 5.0 4.7 0.3 0.0 1.1 7.8 0.1 0.5 0.3 0.9 3.4 139.9 1.5 0.9 1.0 0.0 0.1 0.0 246.0 0.1 0.1 0.0 0.0 0.1 21.4 0.6 0.4 1.5 0.0 0.0 6.7 0.0 13.5 0.7 0.0 1.0 0.0 0.1 0.7 0.0 0.6 8.4 4.9 0.1 0.0 0.0 0.4 33.8 0.3 0.2 0.0 0.0 0.1 9.1 0.0 2.0 2.3 0.7 0.0 0.0 0.0 0.1 0.0 2.2 0.2 176.9 0.0 6.1 1.8 3.6 1.2 0.6 0.1 0.8 0.1 0.0 0.1 0.2 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Bipolar cells: 224.8;Muller glia cells: 221.7;Rod photoreceptor cells: 196.2" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 183.3;HMC-1: 84.2;REH: 75.1;U-698: 403.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 9.0 4.2 69.4 33.0 141.3 30.3 8.5 706.3 105.2 5.0 347.5 8.6 17.3 8.6 22.5 4.6 5.5 13.4 4.3 40.1 122.6 23.4 14.3 9.4 66.8 301.3 122.7 1.6 3.9 2.8 1.2 8.2 207.3 2.8 7.0 0.5 7.1 3.4 1.9 4.0 19.4 8.8 241.5 34.8 8.7 2.0 283.3 10.0 6.9 3.6 72.0 10.1 3.9 437.2 1.4 3.2 0.6 2.9 0.2 0.2 4.0 0.3 0.4 2.3 0.8 0.9 8.1 183.3 30.1 0.2 7.4 4.2 4.0 0.5 1.4 1.4 2.1 22.1 0.4 0.3 1.2 22.3 84.2 0.3 1.8 1.3 1.0 0.3 4.2 8.1 2.5 15.0 0.4 5.7 2.6 55.5 3.1 2.3 1.3 75.1 0.1 23.7 0.5 3.9 1.4 0.4 5.0 1.6 1.5 3.9 3.3 67.7 1.1 0.4 3.2 0.4 0.6 35.2 61.4 403.4 0.3 30.0 1.6 9.4 12.1 76.2 1.9 16.1 0.9 51.1 0.6 2.9 10.7 49.6 0.8 1.9 65.7 41.3 36.8 7.0 0.5 6.9 69.4 141.3 706.3 105.2 40.1 122.6 301.3 122.7 207.3 241.5 283.3 437.2 187.0 12.8 54.0 0.0 138.3 2.9 1.6 2.3 1.8 224.8 139.5 113.0 7.2 28.6 13.1 16.5 104.3 13.6 94.0 0.4 13.7 2.6 20.5 65.5 88.0 61.7 21.5 23.2 0.7 0.0 2.2 30.6 16.8 86.6 40.4 29.0 37.1 43.2 27.7 101.0 0.8 2.7 65.1 47.4 9.4 30.7 11.1 46.7 8.8 95.5 21.8 221.7 47.4 2.0 1.3 0.1 9.8 4.9 138.6 3.5 5.5 5.9 6.9 196.2 6.6 28.0 51.9 4.8 2.9 3.0 2.3 11.1 48.2 8.7 1.9 6.5 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 711.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 688.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1727.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1727.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 169.3 200.0 143.3 78.4 159.7 48.3 138.4 46.0 229.7 139.4 54.0 131.4 71.7 155.7 84.7 84.9 133.5 96.7 206.1 202.5 294.4 130.2 121.3 181.5 98.1 132.4 128.5 199.0 151.0 105.9 711.9 123.4 137.9 133.4 49.2 51.4 138.7 106.2 105.1 120.5 105.3 79.1 63.8 197.0 126.5 77.7 197.7 44.3 120.8 82.3 41.4 126.2 126.0 129.6 85.6 257.8 163.7 259.1 444.2 210.2 124.5 206.5 208.6 146.4 166.6 49.4 93.8 36.9 211.0 180.9 47.8 39.3 39.9 81.2 63.5 138.4 145.3 39.9 82.1 63.2 302.7 16.8 435.1 402.5 167.0 112.1 76.6 244.2 125.0 59.3 142.5 144.5 106.7 111.5 29.5 79.6 107.4 138.7 52.8 37.0 124.5 154.2 75.2 63.2 116.7 193.9 99.0 60.6 113.8 169.5 83.6 283.2 222.3 122.8 58.5 105.6 47.0 148.9 173.3 38.8 197.7 66.2 77.9 1727.4 256.7 378.7 75.0 129.5 62.0 34.4 59.5 67.7 235.0 28.1 60.8 61.3 25.7 102.3 64.2 34.7 64.5 208.6 143.3 159.7 46.0 229.7 202.5 294.4 132.4 128.5 137.9 63.8 197.7 129.6 66.7 32.1 69.6 59.4 27.0 35.4 93.6 263.1 39.9 101.5 45.9 61.2 22.0 45.8 90.4 57.0 33.3 158.2 27.2 42.5 21.5 52.5 8.7 32.0 49.8 53.9 72.8 18.7 99.1 58.3 107.2 158.8 38.2 31.5 60.3 134.7 88.2 43.1 688.4 121.1 113.4 41.3 126.1 280.9 59.1 15.7 151.6 261.3 92.5 50.6 54.2 94.1 35.0 53.3 70.2 54.3 42.6 143.7 85.8 57.9 78.8 37.1 35.2 47.6 19.7 73.1 59.7 24.2 67.9 32.4 33.4 195.9 28.8 114.1 41.6 68.2 PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 16.2;choroid plexus: 52.8" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 319.5;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 226.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Region enriched" "Detected in all" 5 "cerebellum: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.0;AF22: 10.3;HDLM-2: 5.3;SH-SY5Y: 2.9;U-2 OS: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028389, HPA050367" Approved Vesicles,Mitochondria,Cytosol No No "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Vesicles, Cytosol" "HPA028389: AB_10602145, HPA050367: AB_2681105" "unprognostic (5.20e-2)" "unprognostic (1.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (1.32e-2)" "unprognostic (8.77e-2)" "unprognostic (4.36e-1)" "unprognostic (1.95e-1)" "unprognostic (2.08e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-5)" "unprognostic (2.79e-2)" "unprognostic (4.46e-1)" "unprognostic (3.44e-3)" "unprognostic (2.18e-1)" 0.4 1.7 1.7 0.0 2.9 0.0 0.4 16.2 2.5 0.6 52.8 0.2 0.0 1.1 0.2 0.4 1.1 0.1 0.1 3.4 2.5 0.4 0.0 0.2 1.1 2.9 2.6 2.1 1.0 0.2 2.4 0.4 2.8 0.8 0.1 0.3 0.7 3.0 0.2 0.1 0.1 0.9 2.0 0.7 0.3 1.5 2.2 0.4 0.2 0.0 0.4 0.1 0.3 2.7 0.0 3.0 10.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 16.2 2.5 3.4 2.5 2.9 2.6 2.8 2.0 2.2 2.7 0.1 0.0 0.0 7.8 0.2 0.1 0.0 0.0 1.2 0.5 0.0 1.7 1.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 9.1 2.9 0.6 0.3 0.0 0.0 35.5 0.0 0.0 3.1 0.0 8.2 0.0 0.7 0.0 0.0 0.0 3.3 319.5 0.2 0.0 0.0 0.0 21.0 5.0 0.1 0.0 5.6 0.0 0.4 0.0 127.6 226.8 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.2 0.6 0.2 0.1 0.3 0.0 0.0 0.0 0.1 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PLEKHA2 TAPP2 ENSG00000169499 "Pleckstrin homology domain containing A2" 8 38901235-38973912 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 78.7" "Cell type enhanced" "Detected in many" "B-cells: 94.1;dendritic cells: 132.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004706 Approved Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA004706: AB_1079633" "unprognostic (2.78e-1)" "unprognostic (8.80e-3)" "unprognostic (4.15e-3)" "unprognostic (3.03e-1)" "unprognostic (8.61e-2)" "unprognostic (9.07e-3)" "unprognostic (6.16e-3)" "unprognostic (1.45e-1)" "unprognostic (1.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-2)" "unprognostic (6.59e-2)" "prognostic unfavorable (1.95e-6)" "unprognostic (2.39e-2)" "unprognostic (1.00e-1)" "unprognostic (4.55e-2)" "unprognostic (9.60e-3)" 17.5 15.7 13.6 35.3 11.1 39.7 10.6 6.1 18.3 16.9 13.1 16.9 10.1 15.0 10.6 14.0 15.8 17.7 42.8 25.3 10.2 17.1 9.4 20.1 78.7 10.7 6.9 19.1 6.6 21.2 8.7 17.8 11.8 10.2 12.4 5.4 7.4 18.8 4.5 8.4 16.0 18.9 10.1 43.0 12.6 5.9 10.1 17.9 19.3 8.0 66.1 17.3 10.3 16.3 30.0 6.5 4.1 10.0 10.2 20.1 4.6 35.7 27.2 25.9 21.5 3.7 19.4 164.7 41.3 31.9 22.9 17.9 10.8 21.6 38.4 42.8 1.0 84.7 54.4 4.0 36.9 28.0 32.9 46.3 14.7 13.2 23.6 60.1 4.4 26.3 8.7 45.0 24.1 3.7 56.0 12.8 3.9 23.2 10.2 14.1 22.4 34.6 31.3 24.9 0.5 6.5 41.9 7.4 27.9 6.1 16.9 13.0 6.5 18.5 14.5 3.2 28.5 14.7 14.8 76.3 29.3 28.7 4.2 6.9 1.5 8.1 1.9 2.0 2.0 10.0 2.2 2.3 1.8 12.7 1.4 2.6 3.3 3.9 2.2 5.4 1.9 1.0 13.6 11.1 6.1 18.3 25.3 10.2 10.7 6.9 11.8 10.1 10.1 16.3 8.8 3.2 17.9 15.0 94.1 8.8 15.7 17.1 6.8 1.8 7.2 5.2 40.7 12.8 17.3 40.5 0.0 7.7 132.0 9.0 1.9 7.4 1.0 17.8 28.7 10.9 13.1 12.2 21.2 5.5 17.7 22.2 9.2 25.4 36.8 21.3 19.6 10.2 48.8 58.9 7.7 11.8 6.1 79.6 55.3 2.5 22.7 49.7 16.0 35.6 48.4 12.1 64.9 52.3 4.7 24.5 4.7 25.2 56.4 9.9 15.9 16.3 23.5 1.4 13.1 35.8 24.8 0.7 7.9 5.1 6.7 4.5 53.9 4.4 12.8 35.7 PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837097-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 53.4;Smooth muscle cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 63.4;BJ hTERT+ SV40 Large T+ RasG12V: 49.5;SK-MEL-30: 77.0" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 6 "spinal cord: 45.0" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: AB_2678249, HPA048473: AB_2680409" "prognostic favorable (1.97e-4)" "unprognostic (4.39e-1)" "unprognostic (8.16e-2)" "unprognostic (2.85e-2)" "unprognostic (3.98e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (5.09e-2)" "unprognostic (1.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.84e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (6.38e-2)" 34.0 24.6 8.8 12.1 8.8 0.7 31.7 8.0 9.5 28.7 10.9 43.0 5.6 34.6 5.0 14.3 30.5 11.1 41.4 8.7 10.6 32.4 32.8 25.7 5.8 16.9 14.7 47.5 13.2 9.5 29.9 5.6 10.4 28.3 3.9 2.5 15.1 8.4 19.3 17.2 16.0 10.7 10.8 16.2 21.1 11.0 12.4 5.5 31.0 13.1 3.3 34.4 21.7 10.3 9.0 0.5 9.9 63.4 14.2 41.7 8.0 7.0 24.7 26.8 49.5 5.9 2.5 0.4 11.8 9.8 10.4 2.7 3.5 3.6 4.2 0.0 3.4 2.3 1.7 6.6 11.0 0.0 14.2 21.5 2.2 15.6 1.0 11.1 8.0 11.2 9.5 5.3 7.4 5.4 3.2 0.5 1.5 6.0 0.8 0.3 31.5 0.6 8.3 0.1 0.0 11.0 3.0 2.6 77.0 2.5 3.9 3.0 1.3 8.5 6.8 11.2 1.8 28.3 25.4 5.3 10.2 0.7 23.0 0.0 0.3 0.9 1.8 0.3 1.3 1.7 1.7 1.1 0.1 3.9 2.8 2.6 0.1 0.8 0.3 1.2 0.6 0.9 8.8 8.8 8.0 9.5 8.7 10.6 16.9 14.7 10.4 10.8 12.4 10.3 6.4 0.0 18.7 2.3 1.4 9.6 31.3 17.6 12.0 0.7 11.4 18.3 37.1 17.2 27.2 7.3 0.0 3.3 2.9 3.2 1.9 23.3 0.8 11.6 34.1 7.0 1.2 3.2 0.4 5.1 6.8 41.7 7.7 11.6 0.0 18.8 6.4 13.3 2.9 0.0 0.5 2.5 4.1 0.8 9.2 2.0 41.3 1.9 12.4 1.9 1.3 9.9 2.1 0.5 0.2 6.9 0.5 53.4 0.7 29.8 0.7 14.6 20.5 1.0 6.6 33.0 48.4 4.0 3.7 5.7 9.8 2.9 2.4 16.0 3.3 21.4 PLEKHA7 DKFZp686M22243 ENSG00000166689 "Pleckstrin homology domain containing A7" Q6IQ23 11 16777297-17014414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Gastric mucus-secreting cells: 40.8;Microglial cells: 48.7;Oligodendrocytes: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.7;MAIT T-cell: 2.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 116.4;HaCaT: 75.2;OE19: 58.6;RT4: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038610, HPA066103" Approved Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "HPA038610: AB_10671746, HPA066103: AB_2732738" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (4.30e-2)" "unprognostic (2.51e-2)" "unprognostic (6.95e-3)" "unprognostic (2.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (3.13e-2)" "prognostic favorable (1.89e-15)" "unprognostic (9.74e-2)" "unprognostic (1.17e-2)" "unprognostic (4.81e-1)" "unprognostic (2.65e-2)" 10.3 1.7 10.0 5.5 11.9 0.6 13.3 9.6 7.0 11.2 26.5 18.3 27.3 4.1 3.8 46.0 9.1 7.3 24.0 7.5 14.3 26.4 16.7 8.0 2.3 11.5 17.9 12.7 15.2 17.6 4.2 9.0 11.8 7.0 16.9 27.4 21.5 5.3 2.2 14.1 25.4 3.6 7.3 1.8 23.7 10.1 21.2 4.0 10.9 2.2 6.6 14.0 18.3 10.3 14.2 12.7 11.9 5.5 0.7 0.0 20.7 0.1 0.4 4.9 9.0 22.6 116.4 0.2 5.4 1.9 0.7 75.2 16.9 0.2 3.5 4.2 16.2 39.7 11.2 13.5 0.3 0.1 0.5 0.6 6.4 0.0 0.4 10.7 0.0 14.3 1.7 0.4 2.0 8.7 8.8 0.3 6.1 58.6 12.4 11.5 0.0 3.0 10.9 109.9 8.3 0.9 16.7 44.3 0.6 22.3 11.3 4.1 3.3 0.2 4.1 3.2 2.8 7.6 2.4 16.2 0.1 0.8 0.1 0.1 0.1 3.7 0.3 0.0 2.0 0.1 0.3 0.2 0.1 0.0 0.1 0.2 0.3 0.1 0.0 0.4 0.0 0.2 10.0 11.9 9.6 7.0 7.5 14.3 11.5 17.9 11.8 7.3 21.2 10.3 8.2 3.2 17.0 111.0 0.6 0.6 1.1 1.4 0.6 2.3 6.9 6.1 8.7 7.2 8.6 11.0 25.0 6.7 0.2 12.0 3.9 6.1 16.3 20.5 2.3 4.7 0.0 1.3 19.3 6.0 0.9 1.0 40.8 22.9 2.5 16.1 2.2 2.9 1.8 0.0 26.2 6.5 0.0 1.0 1.4 6.1 0.6 2.7 0.0 48.7 0.8 4.3 1.0 15.6 37.9 10.7 4.1 0.4 1.8 0.8 9.2 10.6 8.0 9.7 0.0 1.0 1.2 0.5 0.5 12.3 0.4 6.0 1.2 2.1 3.1 6.4 PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 24.0;NK-cells: 9.4;T-cells: 16.2" "Cell line enhanced" "Detected in many" "A-431: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA065323, HPA073702, HPA074734" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Centrosome,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Cytokinetic bridge, Centrosome" "HPA063455: AB_2685015, HPA065323: AB_2685467, HPA073702: AB_2732238, HPA074734: AB_2732265" "unprognostic (8.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.38e-2)" "unprognostic (4.04e-2)" "unprognostic (2.18e-1)" "unprognostic (7.22e-2)" "unprognostic (7.21e-2)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (3.34e-3)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "prognostic favorable (7.39e-8)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" 25.2 3.5 44.0 10.7 92.5 16.3 23.4 47.2 74.1 33.9 53.0 39.0 13.0 67.5 5.0 45.8 38.1 22.6 17.2 44.5 46.7 36.0 36.3 14.3 5.6 65.8 66.3 33.8 33.0 17.0 6.8 29.3 60.9 24.2 15.5 2.9 29.2 37.5 9.7 44.9 13.2 26.4 37.9 26.6 22.3 5.7 74.1 4.6 23.7 7.4 4.9 32.2 39.1 179.2 78.4 36.5 29.8 45.3 3.1 0.0 49.0 8.7 10.4 13.8 11.0 38.9 34.3 0.0 15.3 8.6 4.8 74.6 20.3 69.7 4.7 0.2 16.7 35.1 48.3 9.2 4.0 1.3 16.1 3.9 39.6 2.9 24.4 22.9 9.1 0.3 0.0 0.4 4.6 37.5 0.1 32.0 10.0 21.2 37.0 0.4 14.7 5.5 37.0 58.0 9.9 18.0 17.7 26.7 25.1 27.5 29.0 8.0 16.6 6.0 59.8 0.3 12.3 0.1 0.2 0.1 0.6 3.7 10.7 9.0 3.0 18.2 16.2 1.5 11.1 0.0 5.0 7.3 1.0 0.0 0.5 3.6 24.0 9.4 1.0 0.0 1.7 5.3 44.0 92.5 47.2 74.1 44.5 46.7 65.8 66.3 60.9 37.9 74.1 179.2 3.1 3.2 6.2 15.0 0.7 19.4 19.4 15.1 21.6 5.5 16.0 9.8 7.8 12.8 6.0 47.8 0.0 7.9 14.5 24.7 11.7 26.7 0.9 18.6 18.5 4.0 34.7 0.4 1.0 20.6 9.5 7.4 14.3 23.6 1.3 1.9 3.6 10.1 5.5 0.0 3.2 26.9 18.3 6.5 8.0 1.5 7.5 2.7 5.4 6.5 4.6 9.1 45.3 10.6 90.9 35.3 16.7 25.6 2.8 16.1 2.3 9.5 4.0 0.8 26.3 5.1 25.3 0.2 1.6 25.6 21.5 2.6 9.0 10.5 13.2 32.2 PLEKHH2 "KIAA2028, PLEKHH1L" ENSG00000152527 "Pleckstrin homology, MyTH4 and FERM domain containing H2" Q8IVE3 2 43637260-43767987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Endometrial stromal cells: 150.5;Oligodendrocyte precursor cells: 191.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.4;RPTEC TERT1: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077225 Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA077225: AB_2686828" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (4.27e-3)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (6.99e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-3)" "unprognostic (3.03e-2)" "unprognostic (1.29e-1)" "unprognostic (8.57e-3)" "unprognostic (1.82e-2)" 13.1 3.0 2.8 1.7 2.7 0.1 8.9 3.6 2.8 20.9 8.8 11.8 3.7 19.8 4.4 4.6 15.9 7.3 4.8 2.3 2.8 15.9 1.7 27.6 2.9 3.0 3.4 23.0 2.9 5.4 2.0 3.8 3.1 5.1 4.3 1.7 4.8 5.0 1.8 8.4 6.5 9.8 2.7 5.4 5.0 3.9 2.7 0.4 5.5 2.5 1.8 6.2 8.5 2.5 0.5 4.0 1.6 0.0 3.1 7.4 0.3 0.5 2.0 0.8 2.0 0.0 1.3 1.0 0.2 0.6 3.3 2.6 0.5 0.6 1.5 0.0 1.1 0.1 0.6 0.1 0.5 0.0 0.5 2.2 0.6 1.9 0.1 1.1 1.7 1.6 3.9 0.1 0.7 1.1 0.8 0.1 0.9 0.6 3.9 0.0 4.6 0.0 6.3 0.2 1.2 0.6 0.4 0.0 3.9 1.1 0.5 0.1 0.2 4.5 1.3 0.2 1.4 0.9 0.2 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 2.7 3.6 2.8 2.3 2.8 3.0 3.4 3.1 2.7 2.7 2.5 4.6 38.5 8.7 19.2 0.9 8.7 17.5 5.8 6.8 1.0 5.3 8.3 2.9 11.5 12.9 66.2 6.2 0.3 1.3 0.1 5.9 6.2 1.6 5.9 150.5 3.8 0.0 0.0 15.6 1.4 0.3 57.4 3.1 8.8 1.3 42.6 2.2 0.0 0.8 0.0 4.3 0.3 2.0 0.3 8.6 3.3 35.8 1.2 12.4 15.9 0.2 5.8 0.0 191.0 52.7 7.2 0.0 50.4 0.4 9.2 0.3 4.1 7.3 4.1 46.0 40.7 24.6 10.8 5.9 2.6 8.4 0.5 3.6 13.1 0.6 8.7 PLEKHO2 "DKFZp761K2312, PLEKHQ1, PP1628, pp9099" ENSG00000241839 "Pleckstrin homology domain containing O2" Q8TD55 15 64841883-64868002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 103.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.2;Kupffer cells: 52.3;Macrophages: 46.5;Muller glia cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 27.1;granulocytes: 77.3;monocytes: 73.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040055 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 200000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA040055: AB_10793954" "unprognostic (4.32e-2)" "unprognostic (7.32e-3)" "unprognostic (8.60e-2)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.90e-2)" "unprognostic (3.05e-2)" "unprognostic (2.80e-1)" "unprognostic (7.70e-2)" "unprognostic (2.05e-2)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.08e-3)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (1.78e-1)" "unprognostic (5.85e-3)" 37.9 31.8 23.1 30.5 26.9 52.0 22.7 25.0 25.0 17.0 16.7 23.6 10.0 19.8 5.7 13.9 22.4 26.0 16.5 21.7 24.4 14.2 11.8 42.2 34.3 31.8 26.2 14.9 8.2 7.4 10.3 25.4 26.6 17.4 7.8 14.4 9.9 13.9 5.8 10.6 17.8 22.9 27.6 103.2 16.3 8.3 28.0 16.0 29.9 8.2 21.1 25.8 16.7 25.5 6.5 4.2 7.9 7.8 68.0 38.8 18.4 18.5 27.4 19.2 19.6 5.1 4.0 17.1 9.5 37.7 19.5 2.2 9.0 7.4 11.2 26.6 2.7 17.2 1.9 6.0 52.2 19.4 24.7 28.3 6.5 24.0 7.8 16.6 27.0 3.5 5.2 59.5 25.9 1.9 4.1 20.9 15.0 3.2 3.7 14.9 19.0 12.2 3.1 4.4 0.6 6.7 7.7 2.6 25.4 12.9 2.7 26.1 35.3 14.8 13.4 14.1 7.8 22.0 37.1 5.8 16.0 24.8 8.8 22.2 43.2 25.6 13.2 52.3 11.9 9.8 7.4 12.2 27.1 6.8 3.1 6.5 77.3 7.0 73.0 3.1 10.7 36.0 23.1 26.9 25.0 25.0 21.7 24.4 31.8 26.2 26.6 27.6 28.0 25.5 24.9 0.0 5.6 17.3 9.1 5.6 2.3 2.3 0.6 0.6 6.4 8.3 3.6 2.8 2.4 9.2 0.0 4.2 15.9 0.5 3.9 2.4 5.0 1.4 5.9 26.1 0.0 2.1 0.2 1.5 5.9 8.6 0.5 2.3 18.4 2.5 34.2 2.1 63.2 0.0 0.2 0.3 4.1 52.3 24.3 2.9 18.3 46.5 14.2 8.4 18.9 56.8 16.5 2.5 2.7 2.0 0.0 25.6 2.7 3.5 0.0 2.2 2.1 3.8 13.1 10.2 5.9 0.9 2.3 1.9 4.4 6.0 10.5 4.6 0.4 3.4 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 380.7;Extravillous trophoblasts: 257.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "NK-cell: 9.1" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1060.6;T-47d: 396.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 24.3 8.4 25.6 7.4 35.7 9.3 40.6 6.4 31.2 37.9 16.4 11.8 9.3 29.0 9.3 35.5 21.0 32.1 54.7 44.4 10.4 15.7 31.1 32.3 7.2 8.1 12.3 19.3 23.4 5.9 6.3 47.6 8.4 17.7 14.6 2.1 42.9 10.5 7.4 47.3 12.9 26.6 7.3 83.6 10.4 38.1 11.8 7.2 18.0 13.6 7.6 29.8 32.1 16.8 131.1 115.6 38.3 3.1 19.9 31.9 15.1 27.1 44.8 86.3 49.8 8.6 112.1 0.0 176.3 95.2 208.3 159.8 1.7 61.5 75.6 0.3 3.5 0.0 50.8 9.7 106.1 0.6 3.6 18.7 82.0 33.3 90.9 1060.6 175.4 0.0 0.1 4.4 169.8 47.5 0.3 0.2 7.6 12.4 18.5 6.3 106.5 0.0 221.6 25.4 2.3 5.1 82.4 16.0 76.0 66.1 396.9 2.0 231.9 24.3 63.8 11.0 217.8 0.1 0.3 0.3 18.8 0.3 110.7 2.2 0.5 1.9 0.1 1.2 0.0 0.8 0.5 0.0 2.2 0.6 0.9 0.4 1.5 9.1 0.5 1.5 0.4 0.4 25.6 35.7 6.4 31.2 44.4 10.4 8.1 12.3 8.4 7.3 11.8 16.8 144.6 19.2 15.8 5.9 23.4 141.7 194.1 116.1 380.7 3.8 108.5 203.7 128.9 30.0 134.9 18.4 4.2 66.5 22.7 66.3 9.8 109.8 10.9 132.7 67.8 178.7 84.3 2.7 44.3 77.9 257.3 107.8 136.6 165.4 9.5 4.1 89.3 7.7 14.9 0.0 22.8 39.9 124.1 8.1 19.3 5.0 12.8 39.5 24.9 15.9 3.2 3.3 0.0 3.5 4.9 103.2 44.6 10.9 8.2 76.1 38.5 5.5 31.6 2.9 0.0 74.0 106.6 65.1 10.4 184.9 103.4 129.8 21.2 7.4 45.6 63.1 PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 12.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.5;Distal tubular cells: 7.9;Early spermatids: 10.9;Erythroid cells: 9.7;Late spermatids: 10.7;Leydig cells: 19.3;Peritubular cells: 7.9;Proximal tubular cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 14.2;U-251 MG: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" 0.0 0.0 2.9 0.1 3.5 0.4 0.1 6.4 2.8 0.2 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.0 5.3 8.9 0.8 0.1 0.0 0.0 11.0 5.3 0.0 0.0 0.0 0.0 0.0 12.2 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 4.3 0.0 0.0 0.9 3.7 0.1 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.3 0.2 0.0 0.3 0.1 0.0 1.7 1.4 0.0 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 14.2 1.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.9 0.2 0.0 2.8 1.7 1.2 0.1 10.4 0.0 0.0 0.0 2.3 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.9 3.5 6.4 2.8 5.3 8.9 11.0 5.3 12.2 4.3 3.7 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.0 3.7 0.0 0.0 0.0 0.0 7.9 0.3 10.9 0.1 2.5 0.0 0.0 9.7 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.2 1.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 10.7 19.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 7.9 0.0 0.5 0.0 9.0 0.0 0.0 0.0 0.0 4.9 1.5 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 PLPP6 "FLJ46512, FLJ90191, PDP1, PPAPDC2" ENSG00000205808 "Phospholipid phosphatase 6" Q8IY26 9 4662294-4665258 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 82.2;Late spermatids: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "HDLM-2: 99.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018096 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA018096: AB_1855609" "unprognostic (2.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.03e-1)" "unprognostic (4.36e-3)" "unprognostic (1.17e-1)" "unprognostic (4.38e-2)" "unprognostic (6.95e-3)" "unprognostic (1.33e-1)" "unprognostic (5.26e-2)" "unprognostic (9.06e-2)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.99e-4)" "unprognostic (2.56e-1)" "unprognostic (2.28e-2)" "unprognostic (2.87e-2)" "unprognostic (5.88e-2)" 3.6 6.6 3.8 6.2 4.0 1.5 7.3 7.0 5.0 5.0 8.7 9.3 10.5 4.0 12.7 7.4 3.3 4.6 2.8 4.3 3.3 5.4 18.9 3.4 8.2 3.4 3.6 4.0 17.2 7.7 4.7 7.1 3.6 16.4 9.9 5.1 7.7 4.8 1.9 8.2 11.4 3.4 3.3 6.0 11.3 5.9 3.3 6.1 7.1 1.5 8.4 5.2 5.1 3.5 8.2 8.3 8.8 10.9 6.9 7.7 8.8 5.5 7.1 4.4 5.0 2.2 5.3 7.9 2.2 5.5 10.9 10.0 6.2 7.8 4.6 99.2 5.9 15.7 8.7 11.3 6.3 5.7 11.4 8.5 6.2 3.4 7.5 5.8 6.6 8.8 2.7 8.1 5.6 8.8 5.4 15.0 8.1 8.2 2.9 5.3 0.0 6.1 7.6 9.3 22.0 11.1 6.5 5.8 3.5 10.8 8.2 12.7 7.8 3.9 3.3 5.3 3.6 1.7 6.4 2.0 6.1 4.1 3.7 6.8 4.1 3.5 3.1 3.7 3.6 2.6 5.6 4.8 4.2 3.3 9.6 6.9 1.8 4.2 4.4 3.2 8.6 4.1 3.8 4.0 7.0 5.0 4.3 3.3 3.4 3.6 3.6 3.3 3.3 3.5 2.8 6.4 2.7 0.0 2.6 0.0 2.5 0.0 2.8 7.5 4.2 2.7 0.0 5.7 1.3 1.8 2.1 18.6 2.9 9.7 1.9 11.0 82.2 2.1 3.4 3.0 10.9 2.1 0.0 13.9 2.9 2.3 7.1 5.3 0.0 4.1 4.2 15.3 6.5 3.3 0.0 7.3 0.0 4.7 0.0 46.3 2.8 1.7 0.0 0.0 3.0 4.6 3.1 0.0 0.0 10.8 6.5 4.9 1.5 7.5 13.4 2.8 0.0 4.9 0.0 1.7 1.8 0.5 1.1 4.6 0.0 10.4 3.4 3.5 5.1 3.1 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 9.8;brain: 21.1;fallopian tube: 11.1" "Cell type enriched" "Detected in some" 7 "Endometrial ciliated cells: 37.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 61.8;THP-1: 128.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.0 0.0 16.8 0.2 14.1 9.8 2.2 0.0 21.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 11.1 0.1 0.1 14.2 11.5 0.0 0.0 2.3 0.1 4.1 8.2 0.3 0.0 0.2 0.4 0.0 1.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 2.3 0.2 0.1 3.2 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.5 12.2 0.0 0.0 0.0 6.9 0.2 0.1 0.0 0.0 0.7 0.1 0.1 8.4 0.1 0.1 0.3 2.3 0.0 0.0 0.0 5.2 0.0 1.6 0.0 0.5 4.4 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 12.0 0.3 0.0 1.1 0.0 61.8 9.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 15.5 0.3 0.0 0.0 6.3 5.4 128.9 0.1 0.2 0.2 0.3 0.1 0.2 0.5 0.2 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 14.1 0.0 21.1 14.2 11.5 4.1 8.2 1.5 2.3 13.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 37.2 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.4 0.0 1.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.1 5.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PLSCR2 ENSG00000163746 "Phospholipid scramblase 2" Q9NRY7 3 146391421-146495991 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 13.2" "Group enriched" "Detected in some" 30 "Early spermatids: 195.5;Late spermatids: 246.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051352 Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA051352: " "unprognostic (1.11e-1)" "unprognostic (9.83e-2)" "unprognostic (8.94e-3)" "unprognostic (7.53e-3)" "unprognostic (3.81e-2)" "unprognostic (1.51e-2)" "unprognostic (3.67e-2)" "unprognostic (1.84e-2)" "unprognostic (4.11e-1)" "unprognostic (5.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.16e-1)" "unprognostic (1.88e-4)" "unprognostic (4.06e-1)" "unprognostic (9.71e-2)" "unprognostic (3.02e-1)" "unprognostic (1.23e-2)" 0.2 0.1 0.4 0.3 0.2 1.1 0.3 0.2 0.7 0.1 0.2 0.3 0.2 0.1 1.8 0.2 0.7 0.5 0.0 0.1 0.7 0.6 0.2 0.2 0.1 0.9 0.6 0.1 0.9 0.2 0.1 0.2 0.7 0.3 0.4 0.5 0.3 0.5 0.0 0.0 0.2 0.2 0.6 0.1 0.4 13.2 0.6 0.2 0.5 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.0 0.5 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.2 0.7 0.1 0.7 0.9 0.6 0.7 0.6 0.6 0.6 0.4 0.0 0.0 0.3 0.2 0.3 0.1 0.1 0.6 0.0 1.3 0.6 0.0 1.5 0.2 7.3 0.0 0.2 1.5 0.7 1.9 1.6 195.5 1.4 0.1 0.4 1.8 0.0 1.0 0.6 0.1 0.5 1.5 0.7 0.0 0.4 0.4 0.1 0.1 0.0 1.1 0.3 2.0 0.0 1.1 246.0 1.8 0.6 0.0 1.0 0.0 1.2 0.0 0.0 0.2 0.5 1.0 1.5 0.0 0.3 0.1 1.5 1.4 0.3 0.0 0.7 0.3 5.4 2.6 0.1 0.1 0.0 0.2 0.2 0.9 0.3 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXNA3 "6.3, Plxn3, PLXN4, SEX, XAP-6" ENSG00000130827 "Plexin A3" P51805 X 154458281-154477779 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058989 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 94000 "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" Nucleoplasm "HPA058989: AB_2683872" "unprognostic (2.79e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-3)" "unprognostic (8.04e-3)" "unprognostic (1.63e-1)" "unprognostic (9.05e-3)" "unprognostic (1.06e-2)" "unprognostic (2.25e-1)" "unprognostic (2.42e-1)" "unprognostic (6.26e-2)" "unprognostic (1.05e-1)" "unprognostic (4.10e-2)" "unprognostic (1.38e-3)" "unprognostic (2.30e-1)" "unprognostic (3.00e-1)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" 6.5 7.0 5.7 3.5 6.4 1.7 6.0 7.5 7.2 10.7 5.3 7.5 3.6 8.1 4.3 5.3 8.7 3.9 7.1 5.5 8.6 5.8 2.8 8.4 3.8 6.4 7.3 17.0 7.6 2.0 24.8 3.6 7.2 10.5 2.2 1.5 12.0 3.4 1.7 10.1 7.8 2.6 4.6 8.0 5.5 3.7 9.0 2.2 10.2 1.1 2.6 7.4 9.7 8.6 11.2 2.2 6.3 16.1 6.5 8.3 8.4 15.6 3.3 3.6 4.9 8.2 4.6 2.0 8.2 16.9 8.4 9.6 6.4 7.6 1.3 0.9 4.8 2.0 29.0 4.5 5.2 1.0 8.8 11.3 5.5 5.4 0.4 12.4 4.1 3.2 5.2 1.6 5.7 13.8 1.9 8.4 2.0 3.4 4.9 7.2 0.5 0.7 4.8 7.2 13.2 6.8 5.7 10.3 2.6 4.4 6.2 2.4 10.4 7.8 7.0 0.8 6.7 1.2 0.2 2.9 14.5 1.5 2.1 0.7 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 5.7 6.4 7.5 7.2 5.5 8.6 6.4 7.3 7.2 4.6 9.0 8.6 5.2 12.8 7.7 13.4 9.8 8.7 9.0 7.3 9.6 18.7 13.9 10.3 6.5 2.8 6.8 11.0 12.5 3.0 10.3 15.9 0.0 11.5 0.1 14.4 23.2 3.9 7.2 0.0 6.5 5.8 7.2 11.0 17.9 30.4 8.8 21.3 2.9 1.6 8.5 5.0 5.4 15.1 0.0 3.5 9.2 0.8 11.5 10.5 14.2 6.5 4.7 6.5 4.1 6.0 4.1 13.6 11.4 8.6 8.5 10.3 9.4 1.5 10.9 7.8 13.1 26.5 9.4 0.9 2.3 8.1 7.4 9.3 13.2 2.5 9.6 8.2 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1;intestine: 81.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 40.9;Excitatory neurons: 29.0;Extravillous trophoblasts: 63.9;Granulosa cells: 46.9;Syncytiotrophoblasts: 49.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AN3-CA: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.2 43.7 1.9 48.8 0.0 0.6 6.5 53.3 1.3 4.8 81.7 3.4 6.5 1.7 14.0 4.1 2.6 6.5 49.8 40.8 1.9 0.2 0.6 0.0 19.6 22.8 0.9 0.3 0.5 1.8 2.0 21.1 17.2 3.8 7.9 0.4 37.6 2.0 1.8 13.4 15.7 15.0 0.2 15.9 8.8 65.1 1.4 0.3 0.3 0.1 27.4 2.2 28.5 0.3 0.1 0.4 33.9 0.0 0.0 3.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.2 0.4 0.5 0.0 0.0 0.0 3.9 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.3 0.4 0.3 0.2 0.7 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.7 0.0 0.1 2.7 0.9 0.3 0.4 0.0 0.2 1.2 0.0 0.2 0.2 0.0 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 48.8 6.5 53.3 49.8 40.8 19.6 22.8 21.1 15.0 65.1 28.5 0.0 0.0 0.0 18.9 0.0 0.6 0.4 40.9 0.0 21.6 0.3 0.9 3.0 0.0 18.0 0.0 22.9 13.5 0.1 1.7 0.0 0.4 0.3 0.3 4.4 0.3 0.0 0.0 29.0 0.4 63.9 0.5 0.0 0.3 0.0 46.9 0.0 0.0 2.4 0.0 24.2 1.1 12.2 0.0 0.0 0.8 0.0 0.3 1.8 1.0 0.0 3.2 0.0 11.1 13.2 2.9 0.1 0.4 0.0 0.3 20.3 0.4 2.6 19.4 0.0 0.0 4.0 0.6 0.9 0.0 0.6 49.5 0.1 0.6 0.4 1.0 PNISR "bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130" ENSG00000132424 "PNN interacting serine and arginine rich protein" Q8TF01 6 99397629-99425331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038796, HPA075076" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA038796: AB_10672652, HPA075076: " "unprognostic (2.95e-1)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (9.72e-3)" "unprognostic (1.68e-2)" "unprognostic (8.55e-3)" "unprognostic (4.41e-2)" "unprognostic (1.58e-3)" "unprognostic (5.82e-2)" "unprognostic (4.32e-3)" "prognostic favorable (5.27e-4)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (3.43e-2)" "unprognostic (2.59e-1)" "unprognostic (8.89e-2)" "prognostic favorable (1.09e-4)" 68.2 68.8 56.9 52.0 55.4 106.8 75.3 78.4 89.8 103.1 67.5 114.5 51.4 79.7 93.6 51.8 93.2 38.2 84.6 54.3 56.4 67.1 62.2 74.4 78.7 56.7 54.7 123.0 66.0 38.4 112.0 36.4 52.9 91.2 49.4 102.1 76.6 48.1 89.4 64.1 94.1 49.4 49.3 90.6 77.1 39.4 56.9 51.4 114.5 31.2 54.9 81.6 80.3 60.1 26.7 19.5 98.8 72.0 35.3 46.8 45.8 44.1 22.8 25.6 29.9 33.3 49.2 85.8 26.6 25.3 28.7 41.9 49.3 33.3 45.2 75.0 48.8 52.6 105.0 30.6 22.2 73.0 67.9 51.8 50.0 27.4 37.5 95.7 34.2 44.8 59.3 52.5 31.3 25.2 31.8 71.2 55.2 24.5 15.3 62.1 29.6 32.4 47.1 47.1 43.4 51.9 21.7 23.6 35.3 75.4 32.8 58.6 45.0 25.2 28.9 25.7 37.2 35.9 24.3 70.5 37.5 68.3 27.0 12.3 10.8 11.9 12.5 6.4 13.0 19.3 12.0 10.4 5.0 25.8 17.9 16.6 30.0 23.5 7.7 19.6 12.4 3.7 56.9 55.4 78.4 89.8 54.3 56.4 56.7 54.7 52.9 49.3 56.9 60.1 175.8 185.9 237.6 356.2 375.8 195.3 357.3 250.5 165.6 546.2 143.9 192.5 121.2 137.2 215.7 178.4 446.2 158.3 336.4 152.4 74.3 130.8 17.0 132.2 185.7 210.7 247.8 194.4 241.5 104.5 102.1 240.1 100.9 140.5 190.5 344.5 135.7 109.4 99.7 498.0 257.4 129.6 199.4 128.0 236.8 47.9 593.3 152.1 167.2 193.9 261.6 223.6 375.9 270.4 252.6 133.1 176.2 441.2 209.8 293.6 205.8 58.6 179.6 419.9 249.8 288.7 236.3 342.6 181.3 115.5 173.6 180.9 283.8 363.3 151.3 352.4 PNMA1 MA1 ENSG00000176903 "PNMA family member 1" Q8ND90 14 73711783-73714384 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 84.2;Peritubular cells: 84.7;Spermatocytes: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003817, HPA015007" Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Focal adhesion sites" "HPA003817: AB_1079646, HPA015007: AB_1855502" "unprognostic (2.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (7.49e-5)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.90e-1)" "unprognostic (5.35e-2)" "unprognostic (3.63e-1)" "unprognostic (5.58e-2)" "unprognostic (4.58e-2)" "unprognostic (1.67e-3)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (2.23e-3)" "prognostic unfavorable (4.51e-5)" 35.5 30.2 75.0 20.3 80.5 8.8 20.6 55.5 85.6 37.6 34.7 56.7 13.9 46.3 54.6 23.4 38.1 24.6 23.3 77.3 90.0 27.8 4.9 15.5 16.4 62.1 62.5 53.4 9.2 8.0 53.1 21.4 62.9 48.8 16.5 59.9 10.9 89.3 12.0 9.8 24.9 52.3 66.9 19.2 26.0 71.0 78.4 19.0 18.5 10.4 12.5 41.7 26.6 70.3 48.2 42.8 72.3 54.1 53.1 56.0 29.9 49.8 27.8 44.5 32.5 40.6 29.2 1.1 33.8 60.7 42.4 31.6 56.0 29.4 45.7 45.7 34.7 27.2 35.8 30.7 56.8 15.3 41.6 49.8 35.1 53.4 33.5 87.4 68.1 28.7 23.9 29.3 61.2 117.6 30.5 37.1 21.8 24.6 149.0 47.5 45.0 1.1 58.8 1.5 85.4 65.5 87.5 19.9 40.4 43.6 97.0 25.6 66.5 89.3 71.7 54.9 41.1 25.7 42.9 14.2 88.3 21.4 30.3 2.9 1.8 4.7 8.5 3.5 5.8 2.8 10.9 8.7 3.9 3.1 10.4 10.0 1.6 5.6 5.3 0.6 14.2 7.3 75.0 80.5 55.5 85.6 77.3 90.0 62.1 62.5 62.9 66.9 78.4 70.3 13.1 6.4 3.0 21.9 8.8 3.8 6.8 5.0 6.2 48.6 7.0 7.5 19.9 2.8 4.1 14.7 12.5 7.5 10.4 6.7 15.6 10.1 84.2 32.2 30.6 13.5 18.7 3.0 31.4 6.7 11.3 20.5 14.3 10.2 16.5 16.6 20.0 1.6 15.6 58.9 28.9 5.4 14.2 6.8 25.9 57.6 32.6 18.8 19.6 12.2 14.1 65.2 10.3 17.1 21.7 30.2 1.4 84.7 10.9 7.4 1.6 26.6 23.1 49.1 72.3 31.2 44.1 87.2 44.4 4.7 3.8 6.0 20.0 43.8 2.5 3.7 PNMA8A "FLJ10781, KIAA1183L, PNMAL1" ENSG00000182013 "PNMA family member 8A" Q86V59 19 46466491-46471563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.0;Endometrial ciliated cells: 8.4;Granulosa cells: 13.5;Respiratory ciliated cells: 10.9;Theca cells: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 32.9;K-562: 36.3;LHCN-M2: 35.9;SH-SY5Y: 31.3" "Low region specificity" "Detected in all" "HPA012956, HPA077702" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA012956: AB_1844328, HPA077702: " "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.42e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-1)" "unprognostic (1.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "unprognostic (9.35e-3)" "unprognostic (1.01e-1)" "unprognostic (6.90e-3)" "unprognostic (1.76e-3)" "unprognostic (9.56e-2)" "unprognostic (1.78e-2)" "unprognostic (2.85e-2)" "unprognostic (1.82e-1)" "unprognostic (6.48e-3)" 1.1 22.8 45.8 0.9 44.8 0.7 4.7 16.2 54.3 5.8 13.9 3.6 0.7 12.5 16.2 1.2 22.1 5.2 15.0 45.4 53.9 8.7 0.4 1.7 0.3 27.0 30.1 17.2 6.3 15.8 36.7 2.6 35.3 8.8 0.7 35.6 6.0 9.6 1.6 1.2 1.3 7.2 23.3 0.6 1.8 22.5 39.8 30.1 15.4 1.1 0.6 3.1 1.6 34.6 0.0 13.9 19.7 19.6 5.6 12.7 3.5 1.3 0.2 2.4 1.2 0.2 1.6 0.1 18.1 0.9 6.8 0.2 32.9 5.3 1.6 0.1 12.2 0.0 0.5 0.5 9.4 0.2 0.2 3.3 6.5 8.2 0.0 1.8 2.0 11.9 36.3 0.2 35.9 0.1 0.2 0.2 16.5 0.0 0.0 0.0 21.5 0.0 8.2 0.1 16.0 31.3 0.1 0.3 0.0 18.0 0.2 0.3 1.2 0.0 0.2 0.2 6.8 0.1 0.1 0.2 0.3 0.1 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.1 0.0 0.0 45.8 44.8 16.2 54.3 45.4 53.9 27.0 30.1 35.3 23.3 39.8 34.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 0.0 0.0 1.8 11.0 0.0 1.9 0.0 0.0 3.9 0.9 0.0 8.4 2.3 0.3 0.0 0.0 0.0 0.0 0.5 2.8 0.0 1.3 0.0 13.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 8.6 0.0 0.0 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470417-108569666 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 236.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: AB_1851849" "unprognostic (4.48e-2)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.73e-2)" "unprognostic (3.48e-2)" "unprognostic (3.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.86e-6)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (4.28e-3)" "unprognostic (1.24e-1)" 27.8 47.3 23.6 17.9 25.1 82.9 20.2 21.6 29.6 19.4 22.1 14.1 11.8 17.9 17.7 21.1 11.6 21.4 25.3 24.0 26.5 30.0 34.6 17.5 18.0 23.5 23.3 14.7 13.9 28.4 16.5 26.6 23.4 18.0 15.1 24.4 11.9 17.7 35.9 15.0 10.7 20.9 24.9 17.7 15.6 15.5 22.9 18.6 24.3 34.7 22.1 29.1 12.7 26.5 28.6 12.8 22.1 19.7 47.7 32.7 32.4 26.6 47.2 21.6 35.8 12.4 16.0 15.9 33.1 26.4 43.4 10.6 37.9 17.1 32.6 24.2 10.1 11.0 19.3 9.1 34.8 7.6 21.7 29.8 31.7 29.2 26.9 23.4 29.5 17.7 13.0 44.5 27.2 18.9 18.0 18.3 9.8 17.9 17.8 6.5 23.3 34.3 25.9 35.9 18.3 25.3 25.8 27.4 32.7 27.7 11.6 12.6 24.2 35.1 15.7 52.8 15.0 37.4 41.5 23.9 33.4 11.4 23.2 21.9 29.8 26.2 14.6 32.8 17.8 28.6 14.2 14.6 29.2 27.3 15.4 14.7 24.5 22.9 43.4 11.6 19.1 22.9 23.6 25.1 21.6 29.6 24.0 26.5 23.5 23.3 23.4 24.9 22.9 26.5 64.5 41.7 49.3 66.3 91.3 92.9 124.0 42.2 55.2 64.0 45.7 35.9 49.7 8.6 51.2 23.9 18.8 58.0 72.7 44.3 93.9 32.0 52.3 124.9 67.3 57.1 57.1 50.7 42.4 37.8 37.5 76.6 45.3 236.1 71.7 19.0 23.2 44.3 32.2 32.0 42.9 27.8 67.1 45.5 90.0 47.4 32.0 113.8 55.2 23.4 43.5 42.9 18.6 38.2 41.3 29.6 38.6 39.5 76.8 80.1 16.7 41.0 62.0 32.5 19.7 88.9 63.9 18.6 23.1 60.5 135.7 130.2 69.1 43.7 22.9 122.7 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 21.0;Spermatogonia: 24.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 0.9 0.9 0.5 5.1 0.3 18.2 3.0 0.5 0.6 2.1 0.0 3.8 2.5 2.5 0.7 3.7 1.0 0.9 0.6 0.2 0.2 0.7 3.1 1.2 5.1 0.2 0.4 1.0 0.8 0.7 0.5 3.0 0.2 1.4 4.5 3.0 1.0 0.7 0.5 3.5 3.6 2.3 0.3 1.5 2.1 4.1 0.2 5.5 0.9 0.9 6.2 1.4 1.9 0.6 37.2 18.6 34.3 16.3 1.7 9.9 18.2 20.4 10.4 31.9 36.7 19.3 27.5 23.6 11.6 11.6 17.5 22.3 35.3 12.8 36.9 27.4 19.6 35.4 20.6 23.9 0.8 41.2 14.6 2.8 0.8 18.5 2.9 4.1 19.0 30.5 30.9 14.3 31.6 32.7 43.6 28.4 20.2 30.9 42.6 35.9 31.7 21.0 11.6 20.6 24.8 14.3 20.5 11.9 6.7 16.5 24.5 15.8 6.7 5.3 38.5 21.4 16.9 10.7 22.7 52.7 9.8 30.1 20.9 0.0 0.0 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.0 0.2 0.0 0.9 0.0 0.2 0.7 0.1 0.5 0.3 0.5 0.6 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 2.0 3.2 0.5 4.2 2.4 4.8 2.1 1.9 2.2 0.8 1.5 1.1 1.2 1.5 1.3 0.0 0.0 9.1 1.0 2.2 0.0 1.3 1.2 0.8 2.6 1.5 1.2 21.0 9.5 1.5 10.6 2.7 1.1 1.5 0.0 4.3 5.0 5.5 5.5 0.0 11.9 2.8 0.0 1.9 1.6 0.8 1.5 1.1 1.8 7.5 1.0 2.0 4.1 12.1 11.5 0.8 0.5 3.0 5.7 1.9 1.1 1.2 0.9 3.1 0.0 2.1 7.4 5.3 24.4 6.0 3.7 3.4 1.7 1.8 4.7 1.5 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" No No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: AB_2673916, HPA049700: AB_2680856" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (7.20e-2)" 5.4 5.7 3.7 5.8 4.0 4.9 4.5 3.1 4.7 4.9 4.0 4.9 4.1 8.2 3.0 6.0 5.2 2.9 5.8 3.9 3.6 4.6 5.0 4.0 4.6 3.4 3.6 5.2 5.2 7.1 4.9 5.0 3.3 4.5 5.0 3.5 3.9 5.1 10.8 5.5 3.8 6.9 2.7 3.8 4.5 6.2 4.4 6.2 4.5 7.4 4.9 5.2 4.2 4.3 18.5 41.1 18.0 34.7 17.2 13.7 25.9 16.6 10.9 23.2 14.4 51.9 14.2 41.9 17.2 17.0 22.7 20.9 46.6 24.4 20.6 17.6 24.0 36.2 18.0 35.1 12.1 34.8 18.7 10.5 15.0 34.6 26.7 8.8 18.2 19.0 48.8 10.3 16.2 16.4 25.8 15.1 32.7 24.4 26.8 30.7 39.5 19.6 10.5 29.7 27.7 14.6 18.3 23.8 12.7 12.3 14.0 12.0 29.3 28.0 22.2 24.3 33.8 14.5 15.3 35.7 14.6 29.3 25.3 0.5 0.4 0.0 0.7 0.6 0.9 0.5 0.3 0.6 0.4 0.6 0.3 0.4 0.1 0.5 0.5 0.7 0.1 0.4 3.7 4.0 3.1 4.7 3.9 3.6 3.4 3.6 3.3 2.7 4.4 4.3 4.9 3.2 9.1 13.4 8.8 4.2 4.9 5.3 12.0 12.4 6.2 5.5 11.1 8.6 4.7 9.2 16.7 6.3 7.2 5.1 3.9 6.0 3.0 5.4 13.8 6.5 9.6 10.9 19.7 4.9 5.4 7.7 8.2 6.9 6.3 11.0 4.2 8.3 12.5 11.8 18.1 6.7 2.0 3.1 3.5 1.7 6.2 5.5 5.4 6.5 3.3 4.2 6.2 20.1 18.2 6.6 3.0 5.3 10.1 9.1 3.5 3.4 5.2 9.7 0.0 14.3 6.2 5.0 7.2 13.4 2.7 3.8 7.5 12.4 10.4 4.0 POLR1G "A34.5, ASE-1, CAST, CD3EAP, PAF49, RPA34" ENSG00000117877 "RNA polymerase I subunit G" O15446 19 45406644-45410737 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 15.8;Extravillous trophoblasts: 26.3;Hofbauer cells: 11.5;Syncytiotrophoblasts: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.5" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.5" "Cell line enhanced" "Detected in all" "U-251 MG: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041664, HPA041734" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA041664: AB_10795693, HPA041734: AB_10794489" "unprognostic (1.03e-1)" "unprognostic (8.98e-2)" "unprognostic (9.28e-2)" "unprognostic (1.37e-3)" "unprognostic (2.46e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (4.79e-9)" "unprognostic (1.62e-3)" "unprognostic (3.21e-1)" "unprognostic (5.01e-2)" "unprognostic (2.99e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-9)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.38e-2)" "unprognostic (4.53e-2)" 3.2 2.4 2.9 3.3 3.0 2.1 3.1 4.1 4.3 2.4 1.1 2.5 2.4 2.7 1.4 4.3 3.0 2.8 3.5 2.9 2.4 2.7 2.6 2.0 3.5 3.4 2.6 3.5 3.8 2.9 1.9 2.2 3.6 2.2 2.1 2.7 2.8 1.9 6.7 4.4 1.9 3.0 1.1 2.1 1.8 1.8 3.4 2.1 2.3 4.5 4.0 4.1 2.4 3.8 31.4 29.0 5.3 20.6 7.5 6.5 20.3 15.3 5.2 26.2 15.1 32.5 21.5 48.3 14.8 11.3 20.6 29.5 46.4 43.0 18.4 22.1 28.7 24.3 11.0 23.9 12.8 25.3 8.9 9.4 27.3 38.2 20.7 7.0 19.2 16.0 63.0 8.9 25.6 37.0 18.7 9.3 37.0 34.6 27.3 25.1 19.5 32.2 10.5 22.7 30.8 9.6 30.9 40.6 6.4 10.6 19.9 15.4 18.2 36.5 36.7 20.4 200.5 16.1 74.0 51.6 16.8 37.6 25.9 1.5 2.7 0.3 1.4 3.5 3.1 2.7 2.0 2.2 4.2 3.0 2.9 3.5 1.3 3.3 2.8 14.5 1.3 2.0 2.9 3.0 4.1 4.3 2.9 2.4 3.4 2.6 3.6 1.1 3.4 3.8 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 15.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 26.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 POLR3G "C31, RPC32, RPC7" ENSG00000113356 "RNA polymerase III subunit G" O15318 5 90471748-90514557 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.8;Inhibitory neurons: 21.2;Oligodendrocytes: 70.8;Spermatogonia: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 84.5" "CAB010109, HPA052658, HPA074330" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies, Cytosol" "CAB010109: AB_2165718, HPA052658: AB_2681904, HPA074330: " "unprognostic (4.31e-1)" "unprognostic (5.35e-2)" "unprognostic (2.62e-2)" "unprognostic (3.55e-3)" "unprognostic (1.18e-1)" "unprognostic (3.42e-2)" "unprognostic (4.19e-6)" "unprognostic (2.17e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-2)" "unprognostic (3.52e-2)" "unprognostic (9.71e-2)" "unprognostic (1.21e-14)" "unprognostic (3.86e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-2)" "unprognostic (8.17e-5)" 1.8 0.6 3.5 2.4 4.5 3.0 2.0 6.3 5.9 1.3 0.7 1.6 1.8 1.5 4.7 4.3 1.2 1.3 1.8 3.6 6.0 0.9 2.2 1.6 4.7 5.7 4.4 1.9 2.4 2.0 0.9 1.8 6.8 1.7 1.5 3.3 2.3 0.5 3.0 4.3 1.4 0.8 1.9 1.8 1.2 4.5 4.2 0.8 3.2 0.8 1.9 2.0 1.7 6.3 24.1 13.0 18.8 5.3 5.9 8.2 7.7 11.9 4.3 19.8 16.8 9.0 18.8 63.7 4.2 5.3 20.0 11.6 20.8 23.2 69.2 29.6 19.6 26.2 8.1 15.1 9.5 19.4 6.2 6.7 8.1 32.7 25.8 4.6 27.2 26.5 35.8 6.4 8.3 13.2 19.1 14.1 78.1 4.0 63.2 16.5 7.4 40.2 5.9 3.2 22.0 6.4 3.7 9.6 35.1 7.7 5.4 6.2 29.1 10.3 21.2 13.2 48.3 13.5 36.7 50.0 22.1 23.7 84.5 3.3 0.2 0.2 1.5 0.4 0.7 1.7 0.5 0.9 0.4 0.9 1.1 1.2 0.7 2.9 1.5 1.0 0.2 0.3 3.5 4.5 6.3 5.9 3.6 6.0 5.7 4.4 6.8 1.9 4.2 6.3 3.2 6.4 2.2 11.8 2.8 3.6 1.6 1.5 1.8 3.0 2.8 3.7 5.2 0.0 0.7 1.8 8.4 0.8 0.7 0.9 3.9 2.4 4.5 1.6 2.3 2.0 6.7 8.8 24.8 4.4 5.4 3.8 0.5 1.2 7.0 1.6 4.6 2.6 1.7 3.3 21.2 1.4 0.0 0.3 0.3 1.0 0.3 1.2 1.8 5.6 0.0 1.1 1.0 14.6 70.8 4.1 3.0 1.2 5.4 6.1 0.4 1.5 3.0 0.8 0.0 1.1 1.8 7.2 26.6 6.3 8.5 0.8 1.7 6.5 2.0 0.8 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320883 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 37.5" "Cell type enhanced" "Detected in many" "Astrocytes: 27.1;Oligodendrocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA003663: AB_1079655" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.40e-4)" "unprognostic (7.10e-3)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-3)" "unprognostic (1.94e-3)" "unprognostic (8.50e-3)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.75e-3)" "unprognostic (3.46e-2)" 5.8 12.4 13.2 4.1 14.9 2.5 5.7 13.5 13.4 8.0 12.5 6.7 2.6 6.7 9.8 5.5 5.8 4.0 7.9 12.7 13.1 10.8 9.3 5.6 1.8 14.6 14.6 6.1 8.8 8.6 12.6 7.0 13.4 7.8 3.3 5.6 6.3 6.9 19.1 4.7 4.9 4.6 13.7 5.6 5.9 37.5 14.4 2.9 10.9 8.4 1.9 7.9 5.3 15.4 15.6 19.4 18.6 21.1 13.0 10.3 14.8 13.4 10.8 19.3 16.6 9.6 13.6 4.6 10.6 12.6 27.1 17.1 8.8 13.3 13.5 6.9 12.1 2.8 8.9 7.9 15.8 3.2 8.9 10.5 13.9 18.3 17.8 13.6 11.5 4.5 7.4 10.5 13.0 30.7 5.4 15.0 5.3 21.4 16.2 5.3 18.0 4.1 20.4 11.3 15.6 15.2 8.7 14.6 11.3 12.0 15.1 6.5 9.6 14.6 22.8 17.1 12.0 6.8 14.5 2.1 7.4 4.8 13.2 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.1 13.2 14.9 13.5 13.4 12.7 13.1 14.6 14.6 13.4 13.7 14.4 15.4 3.2 6.4 2.8 27.1 2.0 3.1 2.7 3.4 2.8 7.5 7.2 7.6 4.3 4.3 1.6 1.8 16.7 6.0 1.2 6.5 0.0 7.6 14.3 5.8 6.7 3.1 18.0 0.0 12.9 7.5 10.2 6.1 4.1 7.0 2.5 6.4 2.5 5.7 5.5 8.4 14.5 3.2 2.0 2.2 2.6 17.2 1.8 2.4 1.8 9.4 2.3 5.9 0.0 20.1 30.5 5.5 3.2 4.1 2.1 5.2 2.5 3.6 5.1 15.1 0.0 6.2 5.0 11.3 8.2 5.2 1.8 5.7 1.2 13.9 3.6 1.9 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 313.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 489.2;Proximal enterocytes: 274.2;Theca cells: 647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 328.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 53.4 197.4 19.9 32.1 20.7 17.9 44.7 14.1 18.6 42.0 15.5 35.9 105.2 32.1 29.4 53.6 50.2 37.0 43.3 20.7 30.2 38.1 313.3 55.0 19.9 22.2 24.5 52.2 44.5 77.6 71.4 46.3 20.9 31.8 21.9 12.7 29.9 113.1 56.2 43.8 92.4 28.2 16.9 43.8 41.5 25.5 34.7 38.0 131.3 68.1 23.2 36.6 42.3 15.3 59.6 133.0 57.0 106.3 212.9 79.8 98.0 24.4 79.3 44.7 62.3 100.7 257.0 56.1 21.9 53.1 151.8 28.3 76.0 38.4 19.6 48.1 57.9 26.0 36.9 189.4 146.5 26.2 45.5 163.9 47.4 59.2 43.2 36.3 42.3 27.1 79.1 24.0 40.8 90.9 29.0 49.4 71.7 92.9 74.8 41.0 37.6 61.1 50.0 72.8 59.3 57.4 65.4 328.4 91.0 32.6 94.0 44.2 38.6 41.7 45.8 63.6 48.7 23.8 38.3 39.0 59.3 39.8 54.9 65.9 42.6 60.4 20.6 39.6 17.1 11.0 17.5 19.4 45.6 11.2 17.1 14.7 53.8 25.9 30.2 12.5 19.3 36.6 19.9 20.7 14.1 18.6 20.7 30.2 22.2 24.5 20.9 16.9 34.7 15.3 34.3 38.5 39.7 23.2 17.1 17.1 29.4 172.3 13.1 31.4 20.5 14.0 10.9 54.3 201.4 73.5 12.5 99.9 26.0 97.7 1.9 65.0 27.6 62.1 28.0 27.1 19.8 11.8 10.1 29.4 95.0 40.1 67.8 46.6 24.7 121.4 32.2 489.2 67.8 15.2 17.1 41.7 124.1 35.2 16.1 9.5 75.8 47.3 12.4 11.2 20.5 25.9 12.3 11.6 8.8 27.9 102.0 112.5 17.0 20.7 274.2 31.7 178.6 23.0 65.7 32.7 46.9 21.3 30.8 18.2 14.6 193.2 25.4 647.6 44.5 45.9 POU2F1 "OCT1, OTF1" ENSG00000143190 "POU class 2 homeobox 1" P14859 1 167220876-167427345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 270.6;Excitatory neurons: 187.6;Inhibitory neurons: 184.0;Oligodendrocyte precursor cells: 186.0;Oligodendrocytes: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002608, HPA058559, HPA064323" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" No No "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB002608: , HPA058559: AB_2683756, HPA064323: AB_2685245" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "unprognostic (1.28e-2)" "unprognostic (1.40e-3)" "unprognostic (5.78e-3)" "unprognostic (4.26e-2)" "unprognostic (5.67e-6)" "unprognostic (4.47e-2)" "unprognostic (5.14e-1)" "unprognostic (7.94e-3)" "unprognostic (1.95e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (2.98e-5)" "unprognostic (1.89e-1)" "unprognostic (4.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.17e-2)" 4.0 2.5 5.0 2.2 5.8 3.9 3.4 7.3 5.2 3.6 2.9 3.7 1.3 4.0 2.6 2.7 3.4 1.4 2.6 4.8 3.8 2.9 2.3 3.5 3.0 4.1 4.2 4.1 2.4 3.4 3.6 2.4 3.9 3.2 2.1 12.9 3.0 2.0 4.1 3.5 3.6 1.4 3.8 4.2 2.6 4.3 5.0 3.8 3.3 2.6 3.4 3.4 3.2 4.4 7.4 4.0 14.8 4.5 1.7 1.7 6.1 0.9 1.6 1.7 1.7 8.1 4.2 8.3 3.8 1.5 1.7 5.6 8.8 2.7 2.6 3.3 3.5 5.9 3.9 7.1 1.1 6.5 3.8 1.2 1.6 2.0 3.6 2.1 2.3 5.7 6.4 4.3 2.3 3.7 6.0 4.3 17.4 4.0 2.3 8.7 5.4 3.7 3.1 4.0 9.0 6.9 5.6 4.1 3.7 7.4 4.6 7.9 3.8 3.4 5.3 2.0 3.5 4.4 2.1 18.3 1.6 3.9 4.4 4.6 0.3 0.3 0.2 0.3 0.3 2.0 0.2 0.0 0.4 0.7 0.3 0.2 0.4 0.2 0.3 0.9 0.2 0.4 5.0 5.8 7.3 5.2 4.8 3.8 4.1 4.2 3.9 3.8 5.0 4.4 19.9 12.8 17.2 270.6 25.2 13.4 11.3 9.7 9.6 58.7 12.5 11.8 15.8 14.3 11.6 20.2 102.2 17.8 20.2 12.3 5.9 10.5 26.2 17.7 18.7 19.8 24.1 14.5 187.6 11.6 18.5 17.5 10.2 18.9 19.7 18.7 15.0 13.3 13.3 47.1 184.0 14.3 8.2 52.5 12.4 44.1 25.7 19.9 7.2 114.3 21.7 43.8 14.4 186.0 202.1 16.5 8.0 20.7 33.5 16.1 5.3 8.3 11.5 101.7 26.3 28.4 16.4 17.6 35.7 12.7 11.1 51.7 14.1 11.0 14.5 21.0 POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 48.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.9;Pancreatic endocrine cells: 20.8;Suprabasal keratinocytes: 37.6;Urothelial cells: 14.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;CAPAN-2: 3.6;EFO-21: 1.3;SK-BR-3: 2.5;T-47d: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Nucleoli, Nuclear bodies, Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" 0.1 0.1 0.2 0.1 0.1 0.2 2.0 0.3 0.4 0.8 0.0 0.6 0.9 0.0 1.7 1.3 0.5 0.7 0.1 0.1 0.1 0.3 0.1 1.0 0.2 0.1 0.1 0.1 0.2 6.3 0.4 0.3 0.1 0.6 0.2 0.1 1.1 2.0 0.2 48.0 0.7 0.3 0.0 0.2 0.7 0.1 0.1 0.2 0.7 0.0 0.5 0.4 2.1 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.0 3.6 0.1 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 2.5 0.0 0.3 3.9 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 8.2 0.3 0.0 20.9 10.6 5.0 1.8 0.0 3.0 1.5 0.8 0.0 3.9 11.0 0.0 1.5 0.1 0.9 0.0 5.3 2.2 1.3 0.7 0.3 3.0 0.0 0.4 1.3 0.4 0.6 10.2 4.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.2 8.2 0.0 2.2 5.5 0.0 0.1 5.4 0.0 0.0 0.4 0.0 0.0 0.5 20.8 1.1 0.0 0.0 5.0 0.4 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.1 7.0 37.6 7.9 0.5 0.2 0.6 14.2 PPDPF "C20orf149, dJ697K14.9, exdpf" ENSG00000125534 "Pancreatic progenitor cell differentiation and proliferation factor" Q9H3Y8 20 63520765-63522206 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2997.4;Paneth cells: 2752.7;Proximal enterocytes: 2849.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 26.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040929 Approved Nucleoplasm,Nucleoli,Microtubules Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Microtubules" Nucleoli "HPA040929: AB_10794155" "unprognostic (3.75e-2)" "unprognostic (5.39e-2)" "unprognostic (4.37e-2)" "unprognostic (9.03e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-2)" "unprognostic (1.91e-1)" "unprognostic (2.00e-1)" "unprognostic (4.20e-1)" "prognostic favorable (3.91e-4)" "unprognostic (1.04e-1)" "unprognostic (1.03e-1)" "unprognostic (4.20e-1)" "unprognostic (2.09e-2)" 215.1 72.2 192.7 71.1 203.3 79.6 237.4 194.7 262.1 312.4 108.7 298.3 81.3 217.8 43.8 622.2 185.6 40.8 412.9 164.7 189.8 421.8 134.9 243.4 42.2 220.9 217.1 197.5 197.9 47.1 196.8 30.3 221.9 365.0 60.6 25.6 432.4 93.4 438.3 461.5 167.1 53.4 201.1 117.0 298.8 129.3 202.5 32.1 249.8 64.2 47.3 264.0 410.7 253.9 287.2 87.8 57.9 118.5 65.4 107.9 185.4 169.1 54.1 217.5 85.2 162.8 166.3 60.7 222.8 115.2 83.2 294.3 29.5 196.0 35.5 110.5 58.5 24.8 83.0 31.9 175.3 0.2 124.3 106.5 384.9 55.3 76.4 72.7 86.5 74.9 104.5 138.9 81.1 394.9 288.7 2.7 63.3 228.1 494.5 132.0 132.2 125.7 159.8 117.4 197.1 150.9 170.3 272.6 124.4 39.1 390.7 168.8 147.3 184.1 206.9 245.8 143.5 108.9 93.3 41.1 130.7 70.9 122.6 2.3 3.0 26.0 5.7 3.6 4.7 5.0 5.1 5.4 3.4 5.8 4.3 5.2 1.2 3.0 5.7 4.0 5.7 5.7 192.7 203.3 194.7 262.1 164.7 189.8 220.9 217.1 221.9 201.1 202.5 253.9 328.1 314.1 220.3 15.7 462.8 574.5 714.7 1076.0 375.6 51.8 1282.8 1173.8 70.1 906.5 763.6 960.0 12.5 428.4 422.5 2528.3 2997.4 916.1 222.0 440.1 449.6 294.2 796.4 399.0 15.4 755.9 761.0 430.8 1120.8 520.2 337.8 293.3 376.3 224.2 600.6 50.5 12.5 1549.5 850.4 390.4 755.8 1154.3 371.9 366.4 1191.7 6.5 831.8 236.9 435.6 6.6 67.2 971.0 2752.7 288.5 280.4 1021.9 2849.8 1715.5 542.0 60.0 197.2 216.3 541.5 129.0 261.6 1559.8 932.1 414.1 541.7 158.5 1132.9 1492.7 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 480000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 26.8 38.3 38.0 24.4 40.2 25.1 22.8 40.4 77.6 25.4 46.4 33.9 50.6 24.2 19.0 27.7 24.1 18.8 49.6 40.1 44.2 39.5 87.6 19.8 28.6 39.0 39.4 24.2 31.7 17.0 28.6 21.6 40.2 23.5 20.3 36.2 23.3 18.7 88.9 36.1 45.3 18.9 39.6 29.1 29.0 24.1 42.2 24.3 23.9 45.5 25.8 27.4 24.0 46.9 46.7 42.3 41.8 57.7 60.7 45.2 63.1 44.9 24.3 40.3 30.4 55.4 30.9 48.9 19.7 42.0 63.4 35.1 127.9 51.5 48.8 162.9 44.4 87.5 36.5 76.9 46.8 55.6 63.0 28.9 41.2 34.6 51.5 52.0 44.6 81.9 111.0 84.4 45.5 44.6 80.0 49.9 57.9 75.5 55.8 35.9 20.7 41.7 44.6 23.0 70.2 47.1 33.8 69.2 65.6 60.0 31.9 52.2 43.7 40.1 45.3 44.7 60.2 48.3 107.2 62.0 51.1 59.4 41.1 68.8 23.9 55.2 31.1 35.4 36.0 22.3 30.2 29.1 26.4 25.4 30.9 32.0 32.9 40.5 37.7 26.9 37.0 28.0 38.0 40.2 40.4 77.6 40.1 44.2 39.0 39.4 40.2 39.6 42.2 46.9 29.2 6.4 13.4 13.1 24.8 10.1 29.7 17.5 9.1 30.2 19.1 20.8 59.7 25.8 27.9 27.6 22.9 41.5 38.7 17.1 37.2 39.2 39.0 66.1 39.9 25.1 19.6 17.4 24.3 23.0 49.5 24.3 14.3 28.5 32.3 24.4 17.2 18.5 41.9 75.7 28.6 28.3 22.4 17.0 14.7 23.1 20.5 26.0 14.2 9.4 51.6 23.3 48.4 15.1 28.3 29.5 27.4 22.6 22.3 31.6 39.7 33.7 62.3 32.3 6.6 17.7 58.2 96.0 77.5 16.9 11.8 47.6 33.7 33.7 32.0 20.2 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.6;testis: 18.9" "Cell type enhanced" "Detected in many" "Early spermatids: 374.4;Endometrial ciliated cells: 226.5;Late spermatids: 75.1;Respiratory ciliated cells: 228.6;Spermatocytes: 101.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;ASC diff: 9.2;ASC TERT1: 11.5;hTERT-RPE1: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.1 0.9 4.7 0.6 5.2 0.2 3.0 5.7 5.3 3.8 12.2 1.3 1.4 3.0 9.0 1.4 35.6 1.1 2.1 4.8 5.2 4.3 0.6 4.7 0.6 7.5 8.2 5.3 2.3 5.2 2.7 1.1 5.5 1.2 1.0 7.4 2.3 2.7 4.3 1.3 0.7 2.0 7.2 0.8 1.7 18.9 5.1 0.8 11.1 1.7 0.6 1.5 1.2 7.6 1.4 1.2 1.1 6.0 9.2 11.5 0.6 0.0 2.2 0.5 0.1 0.1 1.6 0.0 0.4 0.6 0.8 0.9 1.0 0.0 0.3 0.4 0.4 0.5 0.1 0.0 4.6 0.5 0.2 2.4 5.6 0.2 3.5 8.6 0.7 1.3 0.6 0.4 0.4 0.6 0.1 0.7 0.2 4.0 0.8 0.6 0.0 0.5 4.7 0.1 1.3 2.1 0.1 0.3 3.9 0.3 0.4 0.9 0.3 0.1 0.2 1.0 0.2 0.2 0.1 0.1 1.9 0.1 0.4 0.8 0.1 0.2 0.1 0.1 0.1 1.5 0.2 0.1 0.3 0.5 0.1 0.1 0.4 0.4 0.1 0.4 0.1 0.2 4.7 5.2 5.7 5.3 4.8 5.2 7.5 8.2 5.5 7.2 5.1 7.6 2.6 6.4 6.9 11.8 1.8 2.2 3.7 18.2 2.8 2.4 5.7 7.0 3.7 2.8 22.1 3.7 2.1 0.8 0.4 0.9 25.4 1.9 374.4 226.5 7.3 1.8 3.0 0.4 15.0 1.2 0.8 3.9 2.6 5.8 0.0 4.1 1.1 0.2 0.4 1.7 6.1 2.0 22.4 0.0 0.3 75.1 5.3 1.1 3.6 3.7 0.6 7.8 0.0 8.5 6.2 0.7 0.8 5.3 0.8 3.8 1.5 13.0 228.6 13.4 0.0 5.2 5.6 101.4 21.5 1.9 3.0 0.7 1.2 3.0 2.0 1.5 PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Squamous epithelial cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.5;HaCaT: 191.1;MCF7: 71.5;SiHa: 102.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" 56.3 4.9 2.5 1.0 3.2 0.2 39.8 0.3 4.2 163.0 3.3 10.4 6.5 5.7 7.3 728.1 11.5 7.1 5.7 3.6 0.0 13.2 13.3 18.6 0.4 0.0 2.8 5.9 10.6 4.1 14.3 6.4 1.1 17.3 3.4 2.4 149.5 11.5 12.0 188.4 12.3 1.7 0.0 0.3 11.1 1.9 0.0 3.5 22.1 5.3 57.0 22.0 288.6 0.5 24.0 8.6 0.1 0.1 60.0 86.5 29.6 0.1 1.6 0.2 0.6 39.5 59.5 0.4 13.5 1.2 3.4 191.1 1.3 23.0 0.0 0.0 1.3 0.1 46.3 7.1 3.8 0.1 0.1 4.2 20.7 0.2 7.1 4.6 0.1 0.2 0.2 0.2 0.1 71.5 0.1 0.2 6.0 31.3 18.1 0.1 0.1 30.0 44.6 37.5 30.9 0.3 102.5 33.8 0.3 8.9 17.4 0.5 0.3 0.2 0.3 0.3 0.1 0.4 1.1 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.2 0.3 4.2 3.6 0.0 0.0 2.8 1.1 0.0 0.0 0.5 4.1 73.7 29.1 1.6 1.2 35.1 32.5 30.5 35.9 8.4 18.8 13.8 5.1 35.8 42.6 57.0 6.2 2.1 2.0 3.6 1.9 18.4 0.7 31.6 4.1 8.0 39.4 0.0 6.6 4.5 1.6 38.0 9.2 28.0 0.0 0.8 2.9 12.7 0.7 1.7 2.5 3.8 18.3 0.9 9.0 1.3 55.3 1.4 17.8 1.0 1.2 3.7 2.1 1.0 1.7 23.4 8.3 4.1 0.2 35.1 13.5 1.2 32.5 12.5 0.0 28.7 4.3 3.9 3.1 138.0 51.3 1.4 2.7 0.4 4.8 53.2 PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 65.9;Respiratory ciliated cells: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Vesicles, Cytosol" "HPA030123: AB_10603987" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-3)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-3)" "unprognostic (7.12e-3)" "prognostic unfavorable (9.89e-4)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.80e-2)" 9.3 17.1 24.2 3.5 24.5 25.2 10.3 25.2 38.2 14.5 24.7 12.7 3.9 10.9 8.3 8.9 22.0 4.7 13.1 24.4 24.7 15.5 11.5 8.6 5.7 25.0 25.0 13.8 10.8 7.2 13.7 6.5 24.6 13.4 3.9 12.6 8.7 7.7 7.6 11.2 8.5 6.6 25.0 13.6 10.9 6.9 24.0 5.0 11.9 5.6 5.2 11.6 9.6 25.4 10.0 8.0 12.7 8.5 10.4 9.3 3.5 5.9 5.7 7.5 10.3 10.4 9.3 7.4 14.3 5.3 4.1 6.3 9.8 8.8 7.1 4.6 20.3 9.0 18.9 23.9 8.6 3.0 4.6 7.6 11.0 6.3 9.4 9.4 14.7 7.0 22.8 11.2 5.6 9.2 12.0 8.6 8.2 11.2 18.8 13.6 8.2 16.7 15.1 4.2 9.8 14.7 6.6 10.3 12.0 14.6 19.9 9.5 5.7 6.5 7.1 6.5 7.5 19.4 15.3 10.5 6.8 6.0 4.9 6.3 7.2 5.3 10.4 7.6 7.2 9.0 7.8 7.6 10.4 8.2 6.8 6.9 2.9 12.0 5.2 6.6 16.1 7.8 24.2 24.5 25.2 38.2 24.4 24.7 25.0 25.0 24.6 25.0 24.0 25.4 10.9 3.2 13.7 10.4 9.8 12.0 8.3 16.6 9.1 18.0 12.1 14.1 10.1 4.3 15.6 7.3 22.9 21.4 10.6 3.6 21.5 9.5 9.8 39.1 5.9 8.3 6.0 65.9 5.9 5.6 9.4 9.1 5.1 4.6 6.3 12.3 8.9 6.1 9.3 15.2 7.5 7.3 26.4 4.7 8.4 12.1 10.2 8.0 1.8 5.6 8.1 10.4 8.2 9.0 8.9 6.3 3.8 6.8 16.9 3.2 6.6 17.2 84.4 20.9 6.6 9.6 15.6 12.8 9.3 7.2 14.9 10.4 10.6 11.1 7.5 6.2 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" 70.0 102.4 61.2 102.6 70.8 127.8 63.5 64.0 70.7 62.1 61.2 110.8 95.9 50.5 66.8 184.0 61.1 51.2 122.0 63.5 63.6 121.8 128.2 78.9 147.8 68.3 62.4 33.1 105.1 64.2 59.8 83.5 63.8 81.1 89.6 21.6 100.4 51.0 123.2 105.8 107.1 56.1 63.9 148.7 102.7 34.6 65.8 113.7 88.7 81.3 155.6 74.9 80.6 68.2 283.1 305.6 181.1 270.3 88.4 108.9 185.6 136.1 158.4 267.4 202.3 445.8 328.5 237.2 227.3 208.1 198.4 238.7 213.9 280.2 169.6 256.3 139.9 227.5 129.3 232.7 195.2 295.2 281.1 123.3 181.1 225.7 130.7 125.4 272.2 226.0 217.4 191.1 220.5 619.4 378.2 562.2 303.5 526.7 241.1 262.7 254.0 209.8 262.2 220.7 142.5 236.7 159.2 283.0 439.8 135.3 338.5 201.2 196.4 208.5 208.9 245.3 179.0 190.1 193.2 271.8 244.6 199.9 224.3 921.6 735.9 1234.1 779.2 962.9 604.3 733.4 679.9 792.5 705.3 779.6 412.6 584.2 853.8 688.8 1186.1 500.4 1098.7 2042.5 61.2 70.8 64.0 70.7 63.5 63.6 68.3 62.4 63.8 63.9 65.8 68.2 49.2 76.9 92.2 8.8 165.8 99.9 143.5 305.9 64.3 35.5 81.7 79.1 8.4 102.9 157.8 86.5 10.4 360.4 151.2 377.5 213.2 265.6 2.5 63.1 67.2 101.6 96.9 108.8 8.8 311.1 507.0 68.8 132.0 107.1 109.6 87.1 89.3 113.9 377.1 43.7 7.7 241.3 181.0 219.8 138.5 7.7 49.0 186.5 136.9 9.4 353.0 53.8 408.8 6.0 13.1 318.4 308.4 28.6 206.5 139.0 341.3 297.4 70.5 30.5 98.6 67.1 100.7 13.6 94.6 142.0 121.6 427.3 176.3 100.1 231.7 205.4 PPP1CB "MP, PP-1B, PP1B, PP1beta, PP1c, PPP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 985.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022558: , CAB069426: , HPA065425: AB_2685489" "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 90.9 75.2 55.8 74.7 73.5 119.1 110.5 55.6 74.9 148.6 67.8 109.2 84.8 138.4 104.0 245.7 113.5 103.1 185.2 54.3 73.8 84.4 70.5 73.3 60.4 73.9 61.2 92.7 76.2 126.9 45.9 74.8 74.5 149.1 92.9 70.8 114.6 123.4 386.0 73.7 76.0 159.7 71.8 65.8 81.7 47.6 63.5 71.3 78.8 262.8 91.1 118.0 104.1 88.2 186.0 114.6 391.1 121.7 130.8 121.0 227.0 97.7 110.6 92.2 91.0 102.6 106.9 147.5 119.2 101.5 102.7 111.4 112.6 129.9 109.8 235.9 58.2 111.3 130.1 111.5 284.3 127.8 50.5 93.5 181.3 100.1 207.8 97.4 113.8 77.0 103.6 140.4 123.3 93.2 136.9 110.3 128.3 141.8 89.8 132.2 344.9 112.7 304.3 220.6 106.7 131.3 151.4 166.2 136.2 111.4 80.4 70.6 137.6 122.6 134.6 89.3 119.0 100.4 171.0 299.8 130.1 135.0 93.5 72.4 59.4 84.9 39.8 96.7 50.8 38.6 59.3 46.8 65.4 31.6 51.8 58.8 103.6 61.4 115.2 49.8 74.3 52.8 55.8 73.5 55.6 74.9 54.3 73.8 73.9 61.2 74.5 71.8 63.5 88.2 172.2 93.0 80.6 59.4 147.8 492.1 176.7 101.5 64.9 62.4 208.0 117.0 352.1 112.9 124.1 310.8 27.1 129.6 210.4 324.5 244.6 297.0 514.0 330.2 245.7 129.3 283.0 200.2 68.5 210.5 202.1 147.8 78.5 258.9 146.6 91.2 137.8 108.7 114.7 163.2 71.8 144.2 111.9 182.6 985.1 406.2 196.7 238.1 336.2 59.0 137.9 116.6 55.6 64.3 68.4 236.8 181.3 302.0 100.9 364.9 106.6 227.4 213.3 65.2 631.1 225.8 264.8 55.2 66.6 135.6 458.0 392.9 237.7 65.8 154.4 498.9 PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 21.1" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Late spermatids: 219.8;Spermatocytes: 145.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 21.1 0.3 1.0 0.0 0.8 0.1 0.0 0.7 0.8 0.0 0.3 0.0 0.4 0.0 1.4 1.0 0.0 1.8 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.7 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.4 0.3 1.0 0.7 0.8 1.4 0.1 0.1 0.3 0.1 12.8 8.7 6.2 0.0 0.3 0.6 1.2 2.8 1.1 0.3 0.3 40.6 17.2 8.1 3.7 0.0 3.1 0.0 0.5 1.9 2.5 168.5 1.7 0.1 0.6 6.1 0.0 1.1 11.0 6.6 2.4 4.6 0.8 0.0 0.0 0.0 18.5 0.6 0.0 19.4 0.4 10.2 0.8 0.0 219.8 5.9 0.3 3.6 1.9 3.6 12.0 0.0 3.5 0.7 23.1 0.1 0.7 0.0 0.3 0.0 0.7 1.6 1.7 0.0 0.4 0.8 145.1 2.6 1.3 0.3 2.5 0.0 0.8 0.6 1.0 PPP1R3D PPP1R6 ENSG00000132825 "Protein phosphatase 1 regulatory subunit 3D" O95685 20 59936663-59940305 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Group enriched" "Detected in many" 4 "granulocytes: 3.0;monocytes: 1.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041146 Approved Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Mitochondria" Nucleoli "HPA041146: AB_10793870" "unprognostic (2.50e-3)" "unprognostic (3.55e-3)" "unprognostic (6.90e-2)" "unprognostic (1.23e-1)" "unprognostic (7.23e-2)" "unprognostic (5.87e-2)" "unprognostic (5.73e-2)" "unprognostic (2.39e-3)" "unprognostic (5.54e-2)" "unprognostic (3.27e-1)" "unprognostic (3.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.48e-2)" "prognostic favorable (9.14e-4)" "unprognostic (4.71e-2)" "unprognostic (1.47e-2)" "unprognostic (5.71e-2)" 3.7 2.9 6.7 4.8 7.3 6.3 3.8 7.3 7.4 4.2 4.6 3.7 5.3 3.7 3.4 5.8 3.5 3.0 5.5 5.9 6.6 4.1 1.1 3.5 3.9 7.6 6.9 4.5 3.5 5.1 2.8 5.4 7.1 6.3 3.0 2.1 4.3 5.6 7.1 4.2 5.0 3.8 7.0 4.9 5.4 1.9 6.8 3.3 3.6 9.8 5.1 3.4 3.6 6.7 5.1 3.1 2.1 4.3 4.6 4.8 17.3 6.6 7.1 7.9 3.8 4.9 6.8 2.1 8.0 5.5 4.9 14.7 4.3 4.7 5.1 5.0 3.4 5.6 4.2 2.6 4.2 2.3 15.2 3.4 12.7 2.8 2.4 4.2 4.4 1.4 1.0 0.5 5.1 7.9 1.9 7.5 1.5 9.6 7.3 2.4 0.9 3.3 5.3 8.1 4.0 2.4 8.2 24.6 7.4 3.9 9.0 8.2 4.7 4.6 1.9 4.9 1.1 1.7 4.5 0.5 3.5 8.1 2.9 0.3 0.7 3.0 0.4 0.3 0.3 0.3 0.3 0.3 0.5 0.2 0.3 0.2 1.8 0.4 1.8 0.2 0.4 0.2 6.7 7.3 7.3 7.4 5.9 6.6 7.6 6.9 7.1 7.0 6.8 6.7 10.4 9.6 0.5 12.4 3.3 1.3 4.6 2.6 4.6 7.8 5.7 4.2 6.7 7.2 4.3 5.5 2.1 14.3 4.5 4.0 5.9 1.9 0.4 3.0 4.9 8.6 1.8 1.3 0.9 3.1 6.4 3.3 3.1 3.4 5.7 3.9 9.7 0.4 5.2 13.5 2.4 3.6 0.0 9.8 2.6 1.3 3.1 7.4 5.4 1.0 8.7 11.0 13.4 2.5 1.8 3.5 6.1 4.5 3.7 6.7 6.7 6.2 4.3 11.4 6.6 5.7 4.9 0.4 3.6 4.7 3.1 4.9 5.6 5.1 3.8 9.5 PPP1R3E FLJ00089 ENSG00000235194 "Protein phosphatase 1 regulatory subunit 3E" Q9H7J1 14 23295652-23302859 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 47.0" "Cell type enhanced" "Detected in all" "Early spermatids: 111.9;Late spermatids: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 41.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061600 Approved Approved "Microtubules,Mitotic spindle,Mitochondria" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Microtubules, Mitochondria" "Mitotic spindle" "HPA061600: AB_2684566" "unprognostic (3.45e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.89e-5)" "unprognostic (4.05e-1)" "unprognostic (2.85e-2)" "unprognostic (1.29e-2)" "unprognostic (7.12e-2)" "prognostic favorable (3.10e-4)" "unprognostic (1.73e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-3)" "unprognostic (2.41e-1)" "unprognostic (8.67e-3)" "unprognostic (8.46e-2)" "unprognostic (2.88e-1)" "unprognostic (8.12e-2)" "unprognostic (5.46e-2)" 5.8 8.0 15.2 5.7 17.9 3.9 6.4 17.9 23.8 10.2 9.7 7.4 6.3 6.4 10.1 6.0 9.5 3.3 6.2 15.0 15.3 11.6 11.2 5.7 9.5 18.5 16.5 12.5 10.6 5.7 19.3 2.7 19.4 12.1 5.9 47.0 8.5 6.2 14.9 10.9 13.3 3.4 13.8 15.1 9.0 14.7 17.7 8.2 14.9 5.4 8.2 7.9 8.5 23.3 1.1 3.0 3.6 2.5 6.9 2.9 1.7 1.2 2.2 2.0 1.7 1.7 5.8 11.2 0.8 1.6 2.2 7.6 2.1 1.2 2.5 4.0 2.1 2.0 6.9 4.0 1.8 2.3 4.4 2.5 4.5 1.2 6.1 3.3 0.9 6.0 1.9 9.8 1.7 2.6 2.1 3.6 0.9 3.6 2.8 3.4 2.5 7.2 1.1 2.5 4.5 1.2 1.8 1.6 1.2 1.8 1.9 0.8 1.7 2.4 1.3 4.1 0.9 41.1 4.6 5.1 1.9 4.0 1.5 0.2 0.4 0.2 0.5 1.4 0.6 1.0 0.1 0.2 0.3 0.6 0.5 0.3 0.4 0.2 1.8 0.3 0.4 0.3 15.2 17.9 17.9 23.8 15.0 15.3 18.5 16.5 19.4 13.8 17.7 23.3 5.8 3.2 4.8 30.0 25.4 5.6 9.0 5.3 11.4 59.4 7.8 11.6 8.8 7.2 5.0 20.2 37.5 8.2 12.8 8.0 5.9 2.1 111.9 3.7 6.6 7.2 8.4 7.2 25.0 3.3 2.0 6.1 20.4 4.3 3.8 9.4 7.5 7.2 7.4 32.0 33.0 7.7 4.1 9.5 9.6 62.9 27.4 9.2 10.6 15.9 8.1 20.4 26.8 16.1 56.1 2.4 11.6 25.9 11.9 6.7 19.5 9.5 4.8 38.1 13.1 3.5 5.4 36.5 13.9 8.4 9.1 5.2 15.7 7.2 9.6 8.6 PPP2R3C "C14orf10, FLJ20644, G4-1, G5PR" ENSG00000092020 "Protein phosphatase 2 regulatory subunit B''gamma" Q969Q6 14 35085467-35122517 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 489.7;Late spermatids: 233.5;Spermatocytes: 239.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040835, HPA058834" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Cytosol" "HPA040835: AB_10794152, HPA058834: AB_2683831" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (7.32e-3)" "unprognostic (5.33e-2)" "unprognostic (9.73e-2)" "unprognostic (1.10e-3)" "unprognostic (3.05e-1)" "unprognostic (7.85e-2)" "unprognostic (9.48e-3)" "unprognostic (1.17e-2)" "unprognostic (1.91e-1)" "unprognostic (2.18e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-3)" "unprognostic (8.55e-2)" "unprognostic (8.29e-2)" 19.9 15.5 23.5 23.9 25.0 42.8 17.1 24.4 41.6 18.1 23.3 18.6 21.0 16.2 16.4 12.5 14.0 18.6 22.9 23.8 25.6 14.4 16.1 17.7 31.0 25.3 24.4 15.9 10.2 17.0 17.6 18.8 25.6 17.1 20.3 15.4 13.5 14.1 24.9 7.1 22.5 21.0 24.9 24.4 16.2 71.6 24.4 26.4 12.4 25.7 25.9 22.3 10.4 27.5 41.2 21.8 41.7 33.9 32.4 54.5 29.6 33.0 32.0 41.0 48.0 18.1 32.2 47.2 13.4 33.9 15.5 17.6 20.0 13.8 60.5 47.8 19.3 26.2 11.9 65.2 43.3 51.2 51.7 41.9 14.4 29.0 19.7 24.0 55.7 26.2 25.7 46.3 57.4 28.4 46.4 43.1 37.1 27.4 24.3 50.2 27.1 32.8 15.8 24.1 39.9 37.5 41.7 27.6 57.8 19.9 17.9 57.0 47.9 41.3 17.3 36.0 34.9 44.8 52.4 92.8 22.8 47.9 48.1 66.5 41.6 86.9 23.4 52.5 27.0 31.0 24.8 29.5 36.1 33.1 22.0 26.9 76.9 33.1 42.7 16.3 40.8 34.0 23.5 25.0 24.4 41.6 23.8 25.6 25.3 24.4 25.6 24.9 24.4 27.5 35.5 16.0 24.7 32.7 40.2 11.5 23.3 31.7 9.6 15.9 18.8 14.7 26.3 17.2 25.8 20.2 4.2 19.4 48.1 29.1 33.2 31.2 489.7 23.1 28.1 33.8 31.2 69.7 28.3 36.1 26.2 26.5 19.9 21.7 33.7 31.3 34.6 22.8 61.3 8.4 30.4 26.8 32.6 49.7 36.3 233.5 28.3 42.6 28.4 24.4 71.5 28.7 46.4 36.2 58.8 49.2 22.3 30.5 37.4 24.8 37.8 43.2 25.1 21.5 32.9 24.0 43.1 239.2 58.6 19.6 13.5 34.8 45.2 36.2 24.6 30.5 PPP2R5C "B56G, B56gamma, PR61G" ENSG00000078304 "Protein phosphatase 2 regulatory subunit B'gamma" Q13362 14 101761798-101927989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 525.3;T-cells: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027553 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA027553: AB_10602081" "unprognostic (3.28e-1)" "unprognostic (1.66e-1)" "unprognostic (2.19e-1)" "unprognostic (3.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-1)" "unprognostic (1.23e-1)" "unprognostic (1.99e-1)" "unprognostic (1.31e-3)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.33e-3)" "unprognostic (1.17e-1)" "unprognostic (3.09e-1)" "unprognostic (4.49e-1)" "unprognostic (1.72e-1)" 54.7 58.4 72.7 77.6 75.1 129.2 62.0 67.3 81.2 59.2 55.1 70.7 52.4 53.8 63.5 73.8 49.2 57.7 112.6 89.3 72.5 58.6 89.3 66.8 136.9 73.1 71.1 61.2 59.6 64.1 43.2 45.6 72.4 50.5 74.4 56.2 69.2 55.8 79.2 67.3 57.3 60.8 74.2 72.0 53.8 66.5 71.9 114.4 66.5 73.0 124.6 67.3 44.1 72.8 100.6 67.4 111.8 108.6 99.5 138.8 107.9 92.7 121.5 113.5 107.9 68.2 169.8 272.1 86.9 120.8 79.7 102.7 103.6 98.2 146.6 123.2 48.3 79.0 74.8 66.7 73.3 122.7 162.4 91.9 124.4 78.2 72.1 100.7 103.3 145.3 167.5 111.7 109.7 153.2 124.1 135.1 65.0 200.7 111.2 103.7 125.8 67.8 109.3 112.1 87.2 163.3 125.6 82.2 161.1 78.0 150.2 92.9 103.0 71.1 67.3 276.4 93.0 154.8 249.3 449.4 106.6 89.5 81.0 97.5 72.7 72.6 217.2 94.3 140.0 74.8 139.8 172.3 65.4 68.8 98.4 153.5 133.7 68.2 104.6 95.8 156.2 91.3 72.7 75.1 67.3 81.2 89.3 72.5 73.1 71.1 72.4 74.2 71.9 72.8 51.0 83.3 93.9 61.4 94.4 58.6 45.7 35.0 26.2 30.8 51.7 35.8 133.9 47.1 52.4 36.8 58.4 49.8 525.3 69.3 46.9 38.3 79.6 104.2 39.2 45.9 47.4 45.3 124.6 46.9 46.6 43.4 33.6 54.9 69.6 38.7 59.3 78.5 73.2 26.9 92.2 78.9 38.7 122.9 84.5 69.5 52.5 78.4 85.4 84.3 128.2 49.9 280.2 71.4 89.8 50.6 69.7 45.5 193.9 48.9 51.0 62.8 76.5 43.3 39.5 34.3 54.1 47.1 27.5 36.2 70.3 52.4 323.4 42.7 62.6 71.6 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085376 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 44.3 57.9 34.8 43.2 34.7 63.2 42.5 35.9 38.7 42.8 41.0 49.8 47.0 39.6 47.1 88.3 35.9 32.5 45.6 34.0 35.7 49.9 83.2 46.2 58.6 35.5 34.9 29.4 41.0 46.4 33.5 49.6 35.3 37.8 35.2 18.1 44.0 28.5 60.8 60.8 49.0 32.8 35.6 62.5 49.2 65.4 38.4 61.2 35.4 30.2 63.7 56.3 48.9 36.4 132.7 145.9 95.5 134.0 88.4 73.8 148.5 115.8 127.7 148.7 163.8 129.5 167.9 102.7 145.2 137.0 95.5 105.9 119.3 143.2 87.0 130.1 213.0 70.5 86.0 290.4 133.5 100.1 126.8 107.9 124.7 135.9 85.5 88.4 174.9 130.5 139.6 91.0 115.1 382.2 174.4 180.7 182.2 104.7 77.1 190.9 99.4 180.4 142.5 134.5 91.9 136.8 57.1 169.1 101.8 79.4 156.0 166.0 113.3 86.4 90.4 70.6 90.8 155.4 183.8 122.4 123.1 126.9 107.0 100.6 103.5 236.1 66.5 113.2 47.7 68.5 69.6 74.2 115.8 88.3 62.0 54.1 215.2 51.7 100.1 90.6 95.1 48.3 34.8 34.7 35.9 38.7 34.0 35.7 35.5 34.9 35.3 35.6 38.4 36.4 87.8 51.3 33.4 10.7 85.8 147.2 121.7 206.9 71.2 23.3 94.2 82.8 11.1 82.9 133.5 77.3 29.2 313.7 106.0 217.0 158.5 226.9 156.9 80.5 55.5 91.7 125.6 89.2 8.0 193.3 335.3 66.7 106.0 85.2 69.2 66.7 74.6 94.2 239.3 35.3 8.6 159.3 193.3 105.4 138.4 143.8 62.7 124.4 80.0 9.4 221.1 61.1 118.4 8.0 12.9 345.5 220.8 52.3 97.6 161.3 191.0 198.6 119.7 29.5 72.3 43.4 85.9 228.5 157.8 113.2 172.5 421.0 93.0 61.7 175.9 227.2 PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: AB_1079207, HPA063917: AB_2685153" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (4.40e-2)" "unprognostic (9.95e-3)" "unprognostic (4.10e-2)" "unprognostic (5.71e-3)" "unprognostic (1.05e-1)" "unprognostic (8.34e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (4.53e-2)" 19.3 13.5 14.4 18.2 14.5 50.0 19.6 16.6 15.2 19.1 16.2 21.2 17.2 20.0 15.9 21.4 20.4 12.3 16.2 12.6 13.3 18.3 23.7 20.2 28.3 13.6 14.2 22.0 19.8 16.8 14.8 17.5 13.7 18.4 18.5 10.9 20.8 13.1 24.5 25.4 24.4 15.0 12.7 24.1 20.6 22.3 14.5 27.4 17.7 16.7 25.4 19.5 19.4 16.9 24.5 41.4 34.1 27.1 22.5 20.9 60.9 23.2 21.4 24.5 24.6 35.2 32.1 63.1 30.2 19.2 15.0 27.8 36.6 28.9 39.8 52.0 19.7 32.5 25.7 24.5 26.3 59.1 33.1 15.1 50.4 19.7 31.1 20.1 26.7 29.4 33.5 36.2 33.1 52.1 42.8 38.0 31.2 46.5 29.8 54.0 40.6 26.5 30.3 41.5 41.6 25.4 35.3 77.0 32.5 33.6 39.4 37.8 28.0 19.2 20.6 21.1 26.8 36.0 67.0 69.3 25.2 31.8 34.7 6.2 1.9 2.9 4.9 2.6 6.6 4.6 4.5 4.4 2.1 7.4 5.6 4.8 2.5 9.0 3.7 5.0 6.9 2.6 14.4 14.5 16.6 15.2 12.6 13.3 13.6 14.2 13.7 12.7 14.5 16.9 44.1 32.1 48.3 0.0 83.0 0.0 46.7 0.0 58.1 27.9 35.9 23.5 0.0 32.9 30.3 46.0 20.9 33.9 91.8 21.1 29.4 21.2 13.0 86.9 46.5 33.3 13.3 47.5 0.0 25.1 29.0 27.3 45.3 70.7 20.2 39.8 28.9 51.8 25.8 32.0 0.0 28.2 0.0 48.7 0.0 8.5 37.6 70.7 0.0 0.0 41.8 21.0 44.3 0.0 0.0 27.8 25.7 42.5 75.8 56.6 37.3 23.5 16.8 27.3 26.3 45.9 27.1 91.0 59.9 58.0 0.0 44.3 80.1 33.0 25.8 75.2 PPP4R3B "FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2" ENSG00000275052 "Protein phosphatase 4 regulatory subunit 3B" Q5MIZ7 2 55547292-55618880 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001233, CAB017185" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Centrosome "CAB017185: , HPA001233: AB_1080033" "unprognostic (9.60e-2)" "unprognostic (2.47e-2)" "unprognostic (5.77e-2)" "unprognostic (1.87e-2)" "unprognostic (6.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (3.27e-2)" "unprognostic (8.27e-3)" "unprognostic (7.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (6.03e-4)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" 29.0 27.4 14.8 28.2 15.1 25.8 29.1 20.9 16.9 26.8 20.0 28.1 31.6 23.7 19.3 31.7 32.3 24.7 14.3 13.8 16.9 33.4 48.0 23.4 38.1 15.0 16.3 25.7 32.1 27.4 12.5 24.5 16.2 24.9 27.7 35.3 28.1 23.2 14.7 29.6 32.1 21.8 15.9 28.7 30.8 23.7 15.1 42.2 33.0 20.3 38.7 26.7 16.9 18.7 42.8 33.0 35.6 30.0 37.2 38.9 49.1 34.0 35.9 28.2 24.0 39.5 40.9 57.7 67.5 32.7 44.8 36.4 39.9 27.5 41.4 84.6 16.7 56.7 30.0 52.9 60.3 66.0 45.6 29.8 64.9 34.1 60.1 36.9 45.0 31.6 55.2 57.4 37.7 50.9 42.8 43.7 35.1 55.9 25.3 40.1 53.6 44.6 39.3 43.8 43.4 26.9 36.8 49.9 54.8 23.5 31.6 52.0 36.3 43.3 56.8 21.6 47.2 59.1 47.3 22.3 40.8 61.3 47.2 25.6 16.5 26.9 20.4 20.9 23.2 18.1 21.2 21.6 18.4 18.6 24.5 21.5 19.6 22.5 23.0 9.9 24.0 23.9 14.8 15.1 20.9 16.9 13.8 16.9 15.0 16.3 16.2 15.9 15.1 18.7 46.8 44.8 41.3 0.0 61.8 0.0 48.9 0.0 44.3 44.1 42.7 27.9 0.0 31.5 29.1 16.5 33.3 30.6 51.4 25.3 39.2 32.4 9.5 85.1 43.2 32.9 18.2 46.7 0.0 41.0 28.5 33.9 43.8 39.6 30.3 39.0 26.0 52.5 26.2 53.8 0.0 29.4 0.0 37.7 0.0 7.6 28.0 44.9 0.0 0.0 47.9 53.1 49.4 0.0 0.0 35.4 24.1 36.1 57.2 57.4 46.1 52.9 62.7 38.5 6.6 54.9 28.4 39.1 25.7 53.3 0.0 47.7 56.3 44.6 29.0 57.2 PPP6R3 "C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3" ENSG00000110075 "Protein phosphatase 6 regulatory subunit 3" Q5H9R7 11 68460731-68615334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 186.0;Oligodendrocytes: 213.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017183, HPA038467, HPA038468" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 6600 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "CAB017183: , HPA038467: AB_2676029, HPA038468: AB_2676030" "unprognostic (9.46e-3)" "unprognostic (1.45e-1)" "unprognostic (4.62e-2)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (6.19e-2)" "unprognostic (1.97e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.33e-2)" "unprognostic (1.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.20e-3)" "unprognostic (3.29e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.54e-2)" "unprognostic (6.43e-2)" 28.7 28.0 20.4 31.1 26.7 53.0 31.1 35.0 23.1 27.2 29.4 33.4 27.3 30.9 23.3 32.6 26.2 30.7 32.9 20.0 21.9 29.2 31.9 28.1 37.0 24.2 23.4 38.4 22.7 42.9 24.1 34.7 24.8 32.4 33.5 33.8 28.3 26.1 48.8 29.9 31.0 34.5 21.8 32.9 30.0 36.9 23.1 44.4 43.9 49.0 36.6 32.7 26.4 34.6 72.8 83.6 85.0 59.6 44.5 44.9 66.3 62.0 59.7 70.7 64.2 148.3 71.3 83.4 59.4 58.1 74.3 66.6 94.6 70.2 92.3 81.4 40.6 96.1 83.0 49.8 42.6 92.3 82.5 44.8 46.1 72.6 78.0 39.6 65.3 65.4 83.1 59.7 51.1 96.5 92.8 70.8 42.9 142.1 49.5 86.1 116.0 80.9 46.9 103.8 47.8 57.4 88.5 68.8 128.7 70.4 102.4 48.5 65.3 69.1 65.0 74.4 53.4 47.1 71.2 107.0 50.1 40.1 75.1 14.5 9.9 13.2 11.8 13.3 11.4 11.3 12.6 11.7 6.4 12.8 13.7 12.8 14.1 10.1 15.8 13.2 13.2 6.8 20.4 26.7 35.0 23.1 20.0 21.9 24.2 23.4 24.8 21.8 23.1 34.6 41.5 44.8 37.6 134.8 39.6 33.1 25.4 17.6 25.6 49.8 32.1 24.9 42.3 25.8 33.1 27.6 56.3 19.4 36.6 40.9 15.6 15.4 65.8 33.3 33.1 31.0 30.5 35.6 133.3 16.7 17.0 29.8 36.7 43.1 27.8 31.6 29.6 25.3 17.5 26.9 155.0 29.6 16.2 24.9 27.6 24.8 31.1 29.4 21.4 163.9 22.1 28.6 17.5 186.0 213.6 23.9 36.2 31.6 35.9 37.9 29.4 16.1 25.9 50.2 19.7 29.0 30.2 33.8 31.0 29.2 35.5 32.8 38.6 28.6 26.5 42.2 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRDM10 "KIAA1231, MGC131802, PFM7" ENSG00000170325 "PR/SET domain 10" Q9NQV6 11 129899706-130002835 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.5;Excitatory neurons: 21.3;Inhibitory neurons: 21.2;Oligodendrocytes: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026997, HPA061749" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA026997: AB_1855681, HPA061749: " "unprognostic (4.40e-2)" "unprognostic (2.17e-1)" "unprognostic (5.32e-3)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" "unprognostic (1.52e-3)" "unprognostic (2.19e-2)" "unprognostic (2.48e-1)" "unprognostic (1.87e-3)" "unprognostic (3.33e-2)" "unprognostic (4.45e-2)" "unprognostic (3.57e-2)" "unprognostic (1.87e-1)" "unprognostic (5.69e-2)" "unprognostic (4.88e-1)" "unprognostic (6.23e-2)" "unprognostic (1.51e-1)" 2.8 2.4 2.5 3.1 2.5 7.9 4.2 7.4 3.3 3.2 2.8 3.4 3.4 3.0 3.3 4.0 2.6 2.8 2.0 2.9 3.4 2.2 3.5 3.0 3.9 1.8 1.8 3.4 3.1 3.4 4.6 2.6 1.9 3.4 3.9 4.7 3.1 2.5 6.7 6.2 3.7 2.5 0.9 3.1 4.0 2.4 3.3 6.7 3.0 3.8 4.0 2.6 3.4 4.0 4.7 6.1 7.7 5.1 3.4 4.1 5.1 3.9 5.0 3.2 4.1 6.2 4.8 17.8 4.5 4.6 4.4 6.1 6.4 3.2 5.2 6.6 5.5 12.3 7.5 5.0 2.2 10.9 44.8 2.9 7.1 4.8 3.1 4.9 5.7 5.0 7.0 6.6 4.7 5.2 6.7 5.7 5.9 6.3 4.4 6.5 4.8 2.9 4.7 8.0 8.3 4.3 5.7 6.4 1.7 4.3 4.5 4.8 5.7 7.2 3.4 3.8 5.1 1.7 3.0 25.1 3.2 6.1 5.9 2.4 2.2 6.0 2.6 2.5 2.6 6.8 2.1 2.2 2.1 3.6 3.1 1.4 6.3 4.4 2.7 2.1 2.9 1.4 2.5 2.5 7.4 3.3 2.9 3.4 1.8 1.8 1.9 0.9 3.3 4.0 2.7 3.2 2.7 22.5 3.2 6.1 2.6 1.8 6.8 3.7 3.5 2.2 2.7 1.5 2.0 0.0 0.0 1.5 2.5 6.3 0.0 1.2 3.0 2.9 2.7 1.8 1.8 8.6 21.3 1.1 1.2 2.7 4.6 3.2 1.3 2.7 1.1 2.3 1.6 1.7 21.2 3.1 2.0 3.1 2.9 4.1 2.5 2.8 0.0 13.1 2.1 1.0 1.0 13.6 21.6 0.9 3.2 1.9 2.4 4.6 3.1 1.0 2.3 2.7 0.0 3.9 3.4 0.8 0.8 7.2 5.1 0.5 3.5 1.7 2.7 5.8 PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Early spermatids: 75.6;Inhibitory neurons: 31.9;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 32 "granulocytes: 7.5" "Cell line enhanced" "Detected in many" "U-266/84: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Nucleoli "HPA051406: AB_2681472" "unprognostic (7.74e-2)" "unprognostic (8.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.09e-1)" "unprognostic (7.20e-2)" "unprognostic (9.30e-2)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "unprognostic (5.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.13e-1)" "unprognostic (3.00e-2)" "unprognostic (4.91e-4)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.56e-3)" 3.0 4.0 1.8 1.6 2.0 3.5 3.0 3.2 2.0 5.2 4.2 3.2 1.3 6.0 2.8 2.2 4.6 2.4 3.0 1.6 3.2 1.9 0.4 4.2 0.9 4.1 4.0 10.3 4.8 8.6 3.9 3.5 4.0 4.1 2.9 4.7 1.8 4.3 1.6 1.5 1.8 4.4 4.7 2.4 2.1 3.6 2.9 1.4 5.8 3.0 0.8 2.9 3.3 4.4 2.2 3.4 7.8 0.1 4.5 9.3 9.2 4.7 9.9 4.7 4.2 4.4 1.2 0.4 1.2 6.2 4.5 0.1 0.0 1.0 6.0 0.0 1.4 2.9 3.1 0.3 4.9 10.0 0.1 6.6 2.9 3.3 4.1 4.3 3.4 1.2 0.0 14.2 5.7 0.4 1.5 0.1 5.7 0.8 2.7 0.0 9.3 6.1 1.6 0.0 1.4 6.2 0.0 0.1 0.9 4.0 6.4 4.1 1.4 0.2 2.7 4.8 4.6 13.0 19.7 0.1 3.6 0.1 3.6 0.1 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 1.8 2.0 3.2 2.0 1.6 3.2 4.1 4.0 4.0 4.7 2.9 4.4 7.1 12.8 5.6 51.2 0.5 1.7 2.7 2.4 9.1 9.1 1.1 2.4 8.2 2.8 3.8 1.8 8.4 1.0 0.2 1.5 1.9 2.3 75.6 1.4 9.4 6.3 3.6 0.0 25.0 2.5 2.6 9.6 2.6 1.4 2.5 15.5 3.6 0.0 0.8 0.0 31.9 3.6 4.1 0.3 0.7 31.0 8.7 0.6 1.8 23.4 0.2 7.6 0.0 52.8 8.0 1.5 0.8 9.4 0.7 2.6 0.1 0.2 1.8 7.5 6.6 10.1 6.6 8.2 3.5 4.6 1.7 0.5 1.2 14.9 3.0 0.7 PRIMA1 PRIMA ENSG00000175785 "Proline rich membrane anchor 1" Q86XR5 14 93718298-93788485 "Predicted membrane proteins" "Neurotransmitter degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.7" "Group enriched" "Detected in some" 9 "Muller glia cells: 35.5;Oligodendrocytes: 54.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HAP1: 5.2;Hep G2: 3.3;NTERA-2: 2.3;SCLC-21H: 8.3;SH-SY5Y: 8.2" "Region enhanced" "Detected in many" "basal ganglia: 18.1" "Low region specificity" "Detected in all" "HPA046671, HPA060047" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Nucleoli, Cytosol" "HPA046671: AB_2679744, HPA060047: AB_2684194" "unprognostic (3.60e-2)" "unprognostic (1.97e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.03e-2)" "unprognostic (3.73e-2)" "unprognostic (1.07e-1)" "unprognostic (5.81e-2)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (8.94e-2)" "unprognostic (6.61e-3)" "prognostic unfavorable (2.62e-7)" "unprognostic (2.33e-2)" "unprognostic (2.67e-1)" "unprognostic (7.94e-4)" "unprognostic (4.57e-3)" 5.8 3.0 6.1 2.9 11.3 0.0 3.8 10.8 12.3 17.5 2.5 53.7 2.1 13.9 2.1 8.0 18.3 1.6 8.8 5.2 7.9 2.5 0.8 1.0 0.1 17.1 11.3 5.4 1.3 0.0 0.7 1.0 14.7 15.6 3.7 5.7 5.0 5.0 0.9 3.4 21.6 8.1 12.7 0.2 20.0 1.7 9.1 0.2 1.7 1.4 2.3 11.0 14.4 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.2 0.0 0.0 0.1 0.3 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.3 8.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 11.3 10.8 12.3 5.2 7.9 17.1 11.3 14.7 12.7 9.1 18.4 0.2 0.0 0.0 1.3 0.0 0.5 1.0 0.3 0.6 2.6 0.4 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.4 0.2 0.0 0.0 0.2 0.0 0.0 3.4 2.6 0.6 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.0 1.2 2.8 0.1 0.0 0.0 0.0 35.5 0.0 2.0 54.7 0.1 0.0 0.0 1.2 0.7 0.0 0.1 0.0 0.3 0.0 4.9 0.3 0.7 1.4 0.6 0.3 0.0 0.0 0.0 0.0 0.1 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 267.7;THP-1: 194.0" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 46.1 59.7 10.4 45.4 11.1 90.3 28.9 4.4 11.7 25.9 7.3 43.5 54.8 9.1 39.1 32.7 42.3 32.8 19.6 12.8 11.0 25.6 8.8 44.3 46.8 9.9 8.5 13.6 33.2 20.7 8.2 20.5 7.5 39.3 41.5 2.2 25.9 31.9 6.8 34.0 55.7 16.2 9.5 54.2 65.1 20.8 9.0 16.3 41.8 9.2 62.1 44.2 23.2 12.3 33.5 14.4 5.2 8.7 35.9 21.6 46.2 20.4 25.7 24.5 23.7 34.4 31.9 86.5 8.3 45.6 42.9 14.5 34.1 49.8 20.6 75.2 23.6 50.1 18.3 32.0 23.6 64.8 103.4 17.1 35.8 25.6 23.2 21.8 22.4 9.3 9.7 11.8 36.1 85.0 7.0 81.0 13.0 51.5 23.0 7.6 13.6 20.6 25.5 72.8 8.3 6.5 15.4 267.7 39.6 24.0 22.6 194.0 31.5 11.7 14.4 15.4 19.2 18.1 33.6 45.9 27.6 116.4 22.6 51.8 73.7 50.1 3.6 71.3 2.2 6.2 2.1 2.5 57.0 8.2 2.2 2.0 52.9 6.9 47.7 16.3 2.6 24.1 10.4 11.1 4.4 11.7 12.8 11.0 9.9 8.5 7.5 9.5 9.0 12.3 4.3 3.2 23.5 2.0 25.7 29.2 26.3 8.0 23.9 0.3 11.8 4.3 6.4 14.3 16.1 14.7 0.0 3.1 24.7 61.8 3.9 8.9 34.5 18.5 4.4 2.7 26.5 5.2 3.4 10.7 16.0 6.7 54.0 17.8 5.7 8.9 3.3 2.3 44.8 1.7 4.2 37.1 4.1 47.4 43.0 75.6 9.0 41.5 10.6 20.6 44.9 2.0 8.2 1.0 0.5 13.2 55.4 6.8 25.8 19.7 64.5 13.1 16.5 0.2 6.6 6.5 12.1 23.1 3.7 23.9 27.8 8.8 10.0 10.4 23.0 34.6 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222424-170305977 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: AB_2676124" "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favorable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 6.7 5.0 2.0 6.9 2.4 2.6 10.4 2.0 3.2 12.7 0.3 12.4 11.6 11.0 8.2 15.1 15.9 11.4 6.9 3.4 1.1 13.5 7.3 16.6 4.6 0.4 0.2 13.6 7.0 13.0 3.1 10.9 0.5 17.3 13.1 6.2 17.5 12.7 6.2 6.9 10.8 11.0 0.2 5.2 34.5 12.5 0.9 10.9 24.5 9.8 10.4 16.1 6.2 1.1 81.6 20.2 20.0 21.6 17.3 23.9 32.2 20.4 29.9 26.4 28.3 29.7 38.6 24.7 65.3 28.8 36.4 37.3 37.9 40.0 44.8 18.2 23.5 22.9 24.3 16.6 27.9 20.9 10.0 21.8 27.5 22.6 35.1 42.8 20.9 13.3 25.8 19.8 27.4 28.0 30.5 8.5 42.3 86.4 22.1 21.8 30.7 41.2 42.3 24.4 31.5 25.8 44.1 57.7 20.0 29.5 63.0 14.5 22.4 27.5 21.1 26.0 34.3 33.9 34.9 35.2 19.8 16.4 11.0 0.0 0.6 0.4 1.1 0.6 1.7 0.9 1.5 2.0 0.8 1.2 1.6 0.9 0.3 2.6 0.5 0.8 1.1 0.7 2.0 2.4 2.0 3.2 3.4 1.1 0.4 0.2 0.5 0.2 0.9 1.1 17.6 73.7 82.1 23.2 5.8 57.1 49.5 39.8 30.7 16.4 29.0 19.7 16.2 24.3 45.3 49.7 14.6 30.2 15.0 29.0 25.4 16.5 8.4 42.0 29.7 20.5 29.3 10.5 77.2 22.0 26.6 32.2 59.7 72.3 8.8 20.4 17.5 17.7 10.0 15.2 55.2 28.3 50.8 18.6 26.8 6.8 23.3 11.6 17.8 22.5 12.7 8.8 6.2 33.2 33.5 55.2 18.6 28.6 29.4 99.4 18.7 20.4 31.9 9.4 19.7 23.7 18.7 15.8 20.6 38.5 63.6 20.7 14.8 14.3 28.5 80.1 PRMT9 "FLJ46629, PRMT10" ENSG00000164169 "Protein arginine methyltransferase 9" Q6P2P2 4 147637785-147684163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Rod photoreceptor cells: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036844, HPA042537" Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Microtubules "Nucleoplasm, Cytosol" "HPA036844: AB_10672341, HPA042537: AB_2678043" "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" "unprognostic (4.65e-3)" "unprognostic (2.35e-1)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-2)" "unprognostic (4.14e-2)" "unprognostic (7.29e-2)" "unprognostic (2.11e-2)" "unprognostic (2.33e-1)" "prognostic favorable (3.58e-7)" "unprognostic (1.72e-1)" "unprognostic (4.52e-2)" "unprognostic (1.54e-2)" "unprognostic (1.30e-2)" 3.2 9.9 1.4 2.8 1.8 8.5 4.1 3.1 2.4 2.8 1.8 2.3 1.4 4.6 3.1 2.9 3.3 3.0 2.8 2.0 1.8 4.3 3.4 3.2 3.5 1.4 1.6 11.3 3.3 6.1 3.6 3.0 1.5 3.4 2.6 5.2 2.7 3.3 3.3 2.8 1.8 2.7 1.6 2.8 3.1 7.1 1.7 4.5 5.7 2.5 3.0 2.5 2.3 1.6 2.8 1.8 4.3 3.3 3.3 5.6 3.8 3.1 4.9 4.6 4.8 1.4 3.1 9.8 1.3 2.7 2.3 1.9 5.1 2.6 6.3 3.5 3.0 5.4 3.6 2.3 2.5 8.0 2.8 3.9 2.7 2.8 2.5 3.7 3.9 4.8 5.4 5.5 3.9 1.6 6.8 3.1 2.2 2.7 3.2 4.5 3.7 3.6 3.7 2.2 2.7 4.1 4.9 3.8 2.5 2.8 1.6 1.7 3.3 2.9 2.4 3.3 3.4 6.2 5.3 6.1 3.3 4.8 2.2 6.1 4.2 8.6 4.7 4.7 4.6 7.4 5.7 5.8 3.0 7.2 7.1 6.2 2.8 4.3 3.5 4.4 5.5 2.1 1.4 1.8 3.1 2.4 2.0 1.8 1.4 1.6 1.5 1.6 1.7 1.6 8.7 0.0 5.3 9.8 40.4 0.0 4.2 0.0 26.7 56.5 11.7 21.8 5.9 7.2 0.6 35.0 112.6 14.5 51.6 6.2 5.9 7.0 73.1 9.2 9.5 8.4 17.4 10.3 29.8 6.5 14.8 12.9 11.2 13.0 33.7 15.6 12.8 6.9 17.2 50.5 29.8 7.2 0.0 36.5 0.0 13.4 18.0 63.7 0.0 17.8 10.9 48.1 16.5 20.6 16.3 7.4 6.2 17.0 18.4 4.1 7.4 5.5 1.5 81.1 13.1 6.2 18.5 36.5 19.6 4.3 0.0 15.2 61.2 18.5 6.3 2.0 PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 412.6;Basal squamous epithelial cells: 369.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 875.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 875.9" "Cell line enhanced" "Detected in many" "WM-115: 1039.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" 87.0 92.4 283.8 52.4 308.4 83.7 106.7 255.1 385.9 135.4 415.8 184.2 37.1 125.5 59.1 79.2 79.9 110.1 197.5 315.6 244.8 132.8 79.7 79.2 59.8 262.8 260.8 163.7 41.5 62.8 83.8 66.9 270.1 146.1 70.5 178.6 60.3 148.2 64.0 95.4 47.4 140.8 265.0 75.2 61.6 68.1 302.5 47.9 89.1 74.0 60.0 124.9 83.4 292.8 226.4 141.6 41.7 64.2 329.6 199.9 36.6 363.4 527.6 175.5 177.7 50.0 171.5 40.9 79.2 727.9 391.8 508.8 45.9 498.3 326.2 31.8 39.0 0.2 19.6 193.8 402.0 72.8 16.5 177.5 711.9 701.8 583.9 257.0 152.8 28.6 22.8 142.9 205.1 45.7 28.8 46.2 33.1 99.8 266.4 33.9 110.0 38.3 88.7 40.3 49.2 7.0 98.9 144.3 554.1 56.4 30.2 38.8 224.5 282.9 127.1 158.6 296.1 63.1 129.5 132.9 226.8 51.9 1039.0 875.9 74.1 5.4 67.3 60.9 100.7 25.1 56.9 55.8 62.9 25.6 33.5 40.1 4.6 23.6 50.4 24.6 72.8 72.7 283.8 308.4 255.1 385.9 315.6 244.8 262.8 260.8 270.1 265.0 302.5 292.8 44.9 80.1 45.4 120.2 85.3 412.6 211.8 132.5 369.3 265.4 60.8 103.0 257.7 32.9 68.2 33.1 116.7 7.7 71.8 2.6 11.7 58.1 6.0 14.1 73.2 66.7 29.9 31.8 125.5 14.7 6.3 177.4 14.8 18.2 173.0 25.5 41.0 36.2 63.6 45.4 170.8 5.4 40.7 219.1 200.4 13.6 143.2 126.3 168.9 59.0 54.5 142.4 42.2 95.0 158.8 18.7 4.5 170.0 47.0 120.3 2.2 84.0 38.1 99.0 13.1 73.0 82.3 36.6 4.5 81.6 284.4 14.4 107.2 10.3 8.8 122.6 PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000100033 "Proline dehydrogenase 1" O43272 22 18912777-18936553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 49.2;skin 1: 39.8" "Cell type enriched" "Detected in some" 7 "Astrocytes: 183.1" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 91.3;RPTEC TERT1: 35.9" HPA020361 Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" "unprognostic (2.46e-2)" "prognostic favorable (1.54e-4)" "unprognostic (1.40e-1)" "unprognostic (3.70e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-2)" "unprognostic (6.56e-2)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (7.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (5.34e-2)" "unprognostic (3.94e-2)" 7.9 0.7 5.8 0.4 6.4 0.0 8.5 3.1 9.0 5.0 34.0 3.1 5.6 1.5 0.1 11.6 5.8 0.1 18.6 6.5 2.8 16.7 15.6 20.6 0.2 7.3 4.7 0.5 1.4 0.0 5.4 0.2 2.5 3.2 0.3 0.6 4.2 0.2 49.2 39.8 32.5 0.0 3.3 0.5 3.5 1.7 7.6 0.3 7.4 6.2 0.8 4.2 8.5 3.4 0.0 0.8 0.0 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.0 0.0 2.9 3.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.9 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 4.5 91.3 0.0 0.0 0.0 0.4 35.9 0.9 0.1 0.2 0.8 1.4 0.3 5.2 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 6.4 3.1 9.0 6.5 2.8 7.3 4.7 2.5 3.3 7.6 3.4 0.1 16.0 25.6 183.1 0.0 5.1 0.3 13.1 0.0 0.0 0.2 0.1 1.8 0.0 11.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.6 1.2 0.2 0.4 3.5 0.0 0.5 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 2.0 0.0 1.5 0.1 0.0 0.1 21.4 17.8 0.0 0.6 0.0 14.1 2.1 0.0 2.3 0.0 0.0 0.0 8.0 0.1 21.0 0.1 0.0 1.1 0.6 0.2 0.4 1.0 15.2 0.0 0.3 0.0 1.6 0.2 PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1;skin 1: 60.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 37.1;Club cells: 39.9;Collecting duct cells: 33.1;Squamous epithelial cells: 37.2;Urothelial cells: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 79.5;CAPAN-2: 135.9;HaCaT: 73.2;hTCEpi: 78.4;MCF7: 62.1;RT4: 83.8;SK-BR-3: 117.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" 0.7 0.3 1.1 1.5 1.3 0.3 10.3 1.0 2.1 16.6 0.2 11.4 10.5 1.9 27.9 88.1 5.5 27.0 1.1 0.9 0.6 32.4 0.8 1.7 0.1 1.4 0.7 1.1 10.2 25.5 1.5 4.5 1.2 24.7 9.8 0.4 35.2 27.7 0.7 60.0 4.8 0.8 0.3 0.6 26.3 0.6 1.4 2.0 11.9 0.2 7.9 25.7 37.9 2.1 79.5 0.1 0.2 0.8 0.3 0.1 38.5 0.1 0.2 0.3 0.4 0.8 135.9 0.0 0.0 0.1 0.1 73.2 0.0 42.4 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 78.4 0.1 0.4 1.9 0.0 0.1 0.0 0.1 0.0 62.1 0.4 0.5 0.1 3.7 0.5 0.2 0.0 0.1 0.2 83.8 0.6 0.2 0.0 117.7 0.1 0.9 37.2 0.1 0.0 0.2 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.0 2.1 0.9 0.6 1.4 0.7 1.2 0.3 1.4 2.1 0.4 3.2 4.2 1.3 0.1 6.6 25.2 27.6 14.2 0.4 29.1 14.9 1.7 37.1 39.9 33.1 4.2 19.0 0.1 8.0 11.7 15.6 0.5 2.7 0.6 0.9 3.6 0.0 0.6 11.0 3.5 0.6 25.5 5.5 0.0 0.7 0.0 0.0 2.4 0.0 1.2 10.4 12.2 0.0 0.8 1.4 0.3 0.2 7.2 0.0 0.6 0.1 0.0 1.5 3.2 17.5 12.4 0.7 0.0 14.1 0.7 0.1 12.3 1.1 0.0 0.4 2.2 0.6 0.1 37.2 12.8 11.2 0.2 0.8 17.4 37.5 PRPF40B HYPC ENSG00000110844 "Pre-mRNA processing factor 40 homolog B" Q6NWY9 12 49568218-49644666 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Spermatocytes: 61.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038426, HPA038599" Enhanced Approved "Nucleoplasm,Nuclear bodies,Aggresome,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Aggresome, Cytosol" "HPA038426: AB_10674684, HPA038599: AB_10674689" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (2.44e-3)" "unprognostic (2.36e-2)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (7.50e-6)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.06e-3)" "unprognostic (3.31e-1)" "unprognostic (3.29e-3)" "unprognostic (3.23e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (2.80e-2)" 8.3 16.3 16.3 3.2 15.6 0.7 11.5 13.3 18.8 23.9 13.7 15.6 4.0 17.9 10.4 10.4 19.1 6.4 15.6 16.6 16.5 23.9 9.2 7.4 3.1 16.4 14.5 25.4 16.0 20.3 26.2 6.5 15.9 17.5 3.4 12.3 13.3 11.7 25.2 11.4 7.6 7.8 13.3 9.5 14.5 33.7 14.7 3.5 29.2 13.5 3.4 14.6 14.6 15.3 7.2 10.5 10.3 10.0 8.4 5.4 9.5 5.8 8.1 6.1 3.0 12.2 15.8 5.8 12.0 7.7 8.6 4.2 6.3 20.1 3.1 4.4 2.5 6.1 4.2 4.4 10.6 2.0 7.8 7.7 16.8 6.1 22.0 13.2 4.9 11.7 3.0 3.0 7.3 6.7 1.4 4.2 4.4 8.2 3.9 5.1 1.6 4.8 13.0 6.6 10.9 13.1 4.7 12.8 7.2 9.4 24.5 5.7 2.0 3.7 14.9 4.9 2.5 7.1 4.3 2.4 11.2 1.5 3.5 0.0 0.1 0.0 0.8 0.1 1.1 0.3 0.8 0.3 0.2 0.6 0.8 0.9 0.0 1.3 0.0 0.5 0.3 0.3 16.3 15.6 13.3 18.8 16.6 16.5 16.4 14.5 15.9 13.3 14.7 15.3 5.3 12.8 20.3 15.7 4.1 3.6 8.7 10.2 11.4 19.1 6.6 9.7 1.2 5.7 17.5 18.4 10.4 21.9 1.2 1.5 7.9 13.8 28.9 8.6 7.5 5.2 7.7 3.0 19.3 11.1 7.4 7.2 4.1 5.6 2.5 15.6 8.2 3.1 5.4 11.8 22.9 3.2 12.2 1.6 2.1 23.1 11.8 1.5 3.6 6.5 4.9 8.3 2.1 20.6 17.2 6.8 1.1 12.0 1.1 6.7 1.4 5.6 24.5 19.8 13.1 9.8 9.7 61.3 26.6 8.0 6.0 26.4 3.1 9.2 5.2 5.0 PRR16 DSC54 ENSG00000184838 "Proline rich 16" Q569H4 5 120464300-120687332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 30.4" "Group enriched" "Detected in many" 9 "Excitatory neurons: 171.6;Inhibitory neurons: 188.9" "Cancer enriched" "Detected in many" 5 "prostate cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 77.3;BJ hTERT+: 83.9;fHDF/TERT166: 102.1;HSkMC: 62.5;hTERT-RPE1: 103.0;LHCN-M2: 97.9;U-138 MG: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049254 Approved Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Midbody, Cytosol" "HPA049254: AB_2680693" "unprognostic (1.71e-1)" "unprognostic (3.87e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-1)" "unprognostic (6.61e-2)" "unprognostic (7.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.42e-2)" "unprognostic (8.33e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-2)" "unprognostic (2.06e-1)" "unprognostic (2.54e-8)" "unprognostic (3.05e-2)" "unprognostic (9.13e-2)" "unprognostic (2.65e-1)" "unprognostic (2.38e-3)" 11.0 2.8 2.0 5.2 2.1 0.2 7.9 6.1 3.5 14.9 0.0 5.1 1.7 11.8 1.5 1.8 7.0 5.7 12.7 2.2 5.1 3.0 0.9 9.8 1.1 3.4 1.8 5.6 2.0 1.1 1.7 9.7 3.2 9.3 4.5 7.0 2.6 2.4 26.4 4.0 5.0 8.2 0.7 2.5 4.0 2.4 2.3 0.7 4.4 30.4 0.9 9.5 10.0 1.4 3.7 0.0 8.0 0.0 22.2 77.3 0.0 37.0 83.9 51.5 39.1 0.0 0.2 0.0 0.0 102.1 9.3 0.0 8.1 0.9 53.8 0.0 1.9 0.0 1.2 0.0 21.5 0.2 0.1 62.5 8.9 15.4 48.0 103.0 1.7 0.0 0.1 0.1 97.9 0.0 0.0 0.0 0.9 0.0 1.4 0.0 6.2 0.0 4.3 0.0 0.3 16.1 0.1 0.0 1.1 6.1 0.1 0.1 0.5 117.9 13.3 3.8 19.4 0.3 0.0 0.0 6.7 0.2 4.1 0.1 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.3 2.0 2.1 6.1 3.5 2.2 5.1 3.4 1.8 3.2 0.7 2.3 1.4 1.4 0.0 0.0 14.0 0.4 1.3 6.2 0.0 0.0 7.5 1.5 1.9 3.2 0.0 0.0 0.0 14.6 0.1 0.1 0.0 0.0 0.1 16.8 0.9 18.9 0.8 0.0 0.0 171.6 0.0 0.0 13.5 0.0 0.8 0.0 0.2 0.4 0.0 0.5 15.2 188.9 0.0 0.0 1.8 2.7 11.6 2.8 1.0 1.8 9.4 0.1 2.6 0.0 7.5 3.9 0.2 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.7 0.0 1.4 9.6 0.9 1.4 0.5 0.6 0.5 0.4 3.1 0.0 0.7 PRR22 MGC24975 ENSG00000212123 "Proline rich 22" Q8IZ63 19 5782960-5784746 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 50.1" "Group enriched" "Detected in many" 6 "Early spermatids: 194.8;Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 17.3" "Not detected" "Not detected" HPA044157 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Vesicles, Cytosol" "HPA044157: AB_10960694" "unprognostic (8.09e-2)" "unprognostic (1.53e-3)" "unprognostic (5.19e-3)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-1)" "unprognostic (3.20e-2)" "unprognostic (2.89e-2)" "unprognostic (1.20e-1)" "unprognostic (3.77e-2)" "unprognostic (3.42e-3)" "unprognostic (9.37e-3)" "unprognostic (4.18e-2)" "unprognostic (9.93e-4)" "unprognostic (1.07e-1)" "unprognostic (5.07e-1)" "unprognostic (2.79e-3)" 1.9 2.7 1.6 1.5 1.9 1.9 3.0 1.6 2.8 3.4 0.9 3.9 2.5 2.2 0.6 4.9 5.5 0.6 2.5 1.6 1.4 7.1 11.8 2.3 1.4 2.0 1.5 3.3 6.3 0.5 3.8 0.9 1.6 7.1 0.3 0.8 5.0 0.4 1.4 5.9 5.9 0.3 1.3 6.4 4.0 50.1 2.0 0.9 6.1 0.1 0.5 2.4 3.0 2.2 2.1 3.5 1.5 7.3 0.0 0.2 7.2 1.5 0.6 1.1 1.7 3.6 2.0 3.3 4.0 0.3 0.8 2.6 1.1 1.5 0.2 5.1 11.3 1.5 1.8 1.3 0.6 3.4 17.3 0.8 1.2 1.6 0.5 0.1 0.3 3.9 8.4 0.0 0.9 7.9 4.1 4.3 8.9 0.3 3.6 4.0 1.4 5.2 0.3 2.4 1.9 3.6 0.3 2.6 4.4 0.3 3.0 2.8 1.1 2.6 7.2 9.5 1.8 10.0 8.6 6.4 0.2 7.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.6 2.8 1.6 1.4 2.0 1.5 1.6 1.3 2.0 2.2 0.7 3.2 0.5 1.6 0.8 0.3 0.5 1.3 0.0 5.9 1.8 2.2 0.3 1.5 2.5 3.7 0.0 2.2 1.8 2.3 0.0 1.0 194.8 1.5 1.1 0.9 2.4 0.0 1.6 0.7 1.0 0.9 1.5 2.0 0.0 2.9 1.1 2.6 1.1 5.0 2.1 2.5 0.0 1.3 0.2 87.6 2.1 0.6 0.0 2.8 0.0 2.4 1.0 1.5 2.0 0.8 1.8 0.4 0.1 1.2 4.3 1.5 1.2 6.3 6.6 0.8 0.5 20.4 7.4 1.2 1.1 1.8 0.5 1.6 3.3 0.5 PRR32 CXorf64 ENSG00000183631 "Proline rich 32" B1ATL7 X 126819729-126821786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "tongue: 22.4" "Cell type enriched" "Detected in single" 13 "Cardiomyocytes: 1.3" "Cancer enriched" "Detected in single" 5 "glioma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 3.5;hippocampal formation: 10.7;pons and medulla: 13.5;thalamus: 8.2" "Not detected" "Not detected" HPA048386 Uncertain Approved "Nuclear speckles,Plasma membrane,Centrosome" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear speckles, Centrosome" "HPA048386: AB_2680380" "unprognostic (7.10e-3)" "unprognostic (7.97e-2)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.0 4.1 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 22.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR35 C16orf11 ENSG00000161992 "Proline rich 35" P0CG20 16 560394-565529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 46.5;kidney: 17.2" "Cell type enriched" "Detected in some" 9 "Collecting duct cells: 36.8" "Not detected" "Not detected" "Region enriched" "Detected in many" 20 "cerebellum: 46.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.5" "Not detected" "Not detected" HPA069297 Uncertain Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli "Cytokinetic bridge, Cytosol" "HPA069297: AB_2686113" "unprognostic (6.96e-2)" "unprognostic (3.08e-2)" "unprognostic (5.25e-1)" "unprognostic (8.11e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-2)" "unprognostic (1.17e-1)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 46.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 17.2 0.0 0.0 0.0 0.2 1.5 0.0 1.1 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 46.5 1.8 0.3 0.1 0.2 1.5 2.3 0.3 0.4 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.1 0.0 1.3 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR36 ENSG00000183248 "Proline rich 36" Q9H6K5 19 7868719-7874390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 29.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.4;Breast glandular cells: 9.2;Cone photoreceptor cells: 12.5;Horizontal cells: 10.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 21.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 28.7;SCLC-21H: 8.0;SH-SY5Y: 17.9;T-47d: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062741 Uncertain Approved "Nucleoplasm,Nuclear speckles,Golgi apparatus" Yes No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 14: REH - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Nuclear speckles" "HPA062741: AB_2684860" "unprognostic (3.15e-2)" "unprognostic (1.02e-1)" "unprognostic (6.23e-2)" "unprognostic (5.61e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-2)" "unprognostic (9.62e-2)" "unprognostic (3.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.15e-3)" "unprognostic (1.75e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-3)" "unprognostic (7.89e-2)" "prognostic favorable (7.74e-4)" "unprognostic (3.56e-1)" "unprognostic (8.52e-3)" 0.1 0.9 3.5 0.1 4.0 0.0 2.5 3.0 21.0 0.8 0.0 0.3 0.2 0.6 0.3 0.3 1.2 0.1 0.2 7.5 0.0 3.3 0.2 0.9 0.0 0.0 0.0 0.7 2.8 2.0 29.6 0.0 0.0 2.5 0.0 5.0 4.1 0.3 0.0 0.7 0.2 0.0 0.0 0.1 0.8 0.8 0.0 0.0 1.1 0.0 0.0 0.3 0.3 0.0 0.1 0.9 6.6 5.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 2.9 0.0 1.9 0.0 0.6 0.1 5.1 0.0 0.0 0.0 6.4 0.0 0.3 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.1 0.1 0.0 3.0 0.3 0.3 2.5 0.4 0.6 28.7 0.0 0.3 3.7 5.4 8.0 17.9 0.0 0.3 0.0 0.5 9.1 0.0 0.0 0.0 3.2 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.0 3.0 21.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.8 0.0 2.2 13.4 9.2 7.7 1.3 2.8 0.0 5.5 12.5 0.2 0.2 0.2 5.9 3.0 5.4 4.5 0.7 0.2 3.6 0.0 6.9 0.9 0.4 0.3 2.6 6.7 0.0 1.1 0.0 0.5 0.1 10.1 5.8 0.7 0.0 0.0 0.0 0.7 0.6 0.4 0.0 3.7 0.0 5.4 0.0 4.5 0.8 0.9 0.1 0.0 0.6 1.3 0.1 1.5 0.0 4.5 0.0 0.3 1.1 0.3 3.7 3.1 0.0 0.3 0.3 0.5 0.3 1.0 PRR7 MGC10772 ENSG00000131188 "Proline rich 7, synaptic" Q8TB68 5 177446445-177456286 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 24.7;SK-MEL-30: 26.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046636 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046636: AB_2679730" "unprognostic (3.69e-1)" "unprognostic (9.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (4.08e-2)" "unprognostic (7.94e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (4.75e-2)" "unprognostic (5.86e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.84e-3)" "unprognostic (2.22e-1)" "unprognostic (3.76e-2)" "unprognostic (1.69e-1)" 1.3 4.0 10.7 0.8 11.9 5.8 1.6 1.2 18.7 1.8 6.3 1.3 0.7 2.5 0.0 3.7 4.8 0.1 1.8 17.9 6.7 2.3 2.3 2.0 1.0 2.7 2.1 0.7 2.9 0.4 10.4 0.1 0.7 1.8 0.1 0.3 2.7 0.2 1.2 6.0 1.8 0.1 1.9 3.1 1.3 4.4 7.4 0.5 1.2 0.0 0.5 1.0 2.0 2.8 10.7 4.1 1.1 8.1 0.0 0.6 3.5 4.9 0.9 1.3 1.8 0.9 5.6 10.2 12.6 0.7 4.1 8.8 0.7 4.5 0.5 9.0 12.8 3.1 4.3 3.1 0.9 6.2 7.2 0.9 1.8 0.6 0.3 1.2 0.6 3.9 1.6 7.1 1.3 14.3 5.2 15.8 1.9 1.6 24.7 14.5 3.6 10.5 1.7 0.8 19.8 14.1 1.9 4.8 26.2 0.0 4.3 1.0 3.8 8.0 13.5 7.1 12.0 3.9 2.3 5.1 7.7 9.8 5.9 1.9 0.1 9.7 2.3 0.4 5.5 1.5 2.5 3.9 0.1 2.8 2.4 3.1 3.7 1.7 0.5 2.4 2.0 1.2 10.7 11.9 1.2 18.7 17.9 6.7 2.7 2.1 0.7 1.9 7.4 2.8 11.8 3.2 0.0 4.9 27.9 43.3 28.0 6.8 46.7 13.6 17.2 20.3 1.6 17.2 3.7 7.3 0.0 0.8 55.9 7.4 9.8 10.6 10.6 50.2 12.3 9.2 43.0 3.4 8.6 10.8 0.9 4.8 14.3 22.3 26.7 1.0 4.6 3.1 1.5 6.7 7.0 12.3 16.2 1.9 36.5 13.8 0.9 16.7 28.4 1.0 2.3 19.7 22.6 4.0 5.7 8.6 9.8 2.2 27.3 26.7 11.6 14.2 7.0 16.6 0.0 7.8 8.1 3.3 10.7 33.2 66.9 1.4 37.0 1.5 12.3 17.3 PRR9 ENSG00000203783 "Proline rich 9" Q5T870 1 153217584-153219310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 59.3" "Group enriched" "Detected in some" 5 "Early spermatids: 4.1;Late spermatids: 10.2;Syncytiotrophoblasts: 8.9" "Group enriched" "Detected in many" 6 "cervical cancer: 4.2;endometrial cancer: 4.1;head and neck cancer: 11.8;melanoma: 3.4;urothelial cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SuSa: 17.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA027714 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 61: Skin - Cornification" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Nucleoplasm, Vesicles" "HPA027714: AB_10602194" "unprognostic (1.45e-1)" "unprognostic (1.46e-1)" "unprognostic (4.17e-1)" "unprognostic (3.48e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-2)" 1.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 59.3 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 17.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 PRRC2A "BAT2, D6S51E, G2" ENSG00000204469 "Proline rich coiled-coil 2A" P48634 6 31620715-31637771 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 81.9;HEK 293: 148.3;U-266/70: 75.3;U-266/84: 86.8;U-698: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026383, HPA046791, HPA066501" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 5600 "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "CAB026383: , HPA046791: AB_2679809, HPA066501: AB_2732747" "unprognostic (2.07e-1)" "unprognostic (6.84e-2)" "unprognostic (3.82e-1)" "unprognostic (2.25e-3)" "unprognostic (5.04e-2)" "unprognostic (4.63e-1)" "unprognostic (2.42e-3)" "unprognostic (2.09e-1)" "unprognostic (3.07e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-3)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.01e-1)" "unprognostic (1.57e-1)" "unprognostic (5.40e-2)" "unprognostic (3.10e-1)" 37.2 36.5 0.2 6.8 0.2 0.1 36.3 0.2 0.4 48.8 0.0 47.9 0.5 53.7 12.2 42.0 47.3 0.0 41.5 0.6 0.2 37.4 23.0 36.4 3.4 0.6 1.0 55.7 35.1 0.0 50.4 0.8 0.1 47.5 0.6 2.9 31.8 0.3 54.9 37.6 37.3 0.1 0.2 41.7 37.1 84.3 0.2 4.3 41.9 0.0 0.0 44.1 40.3 0.2 4.4 19.3 0.2 0.7 35.5 33.6 3.3 2.0 0.0 0.0 0.2 0.9 0.2 4.2 24.5 41.8 0.0 1.8 0.0 81.9 0.0 8.1 148.3 4.6 0.2 0.3 0.1 2.0 1.4 14.9 0.0 0.2 0.0 0.0 0.0 30.7 2.0 0.0 0.2 0.7 0.9 0.2 0.4 0.1 1.7 2.2 0.6 0.9 6.9 0.5 2.6 1.3 1.5 0.1 0.7 0.0 0.3 1.5 0.7 0.5 17.6 1.3 0.9 75.3 86.8 78.7 25.7 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.4 0.6 0.2 0.6 1.0 0.1 0.2 0.2 0.2 39.3 0.0 5.5 25.5 39.2 32.9 28.4 26.1 67.7 36.1 41.6 39.0 6.7 18.6 14.5 40.5 60.5 26.9 38.0 48.4 5.9 24.8 58.7 33.3 37.1 33.4 38.9 47.9 19.2 25.6 22.2 32.9 52.0 35.9 10.8 55.5 33.5 22.5 34.6 37.0 19.7 39.1 26.4 28.2 30.9 23.7 49.0 31.4 19.6 15.9 28.7 20.9 39.1 23.1 15.3 34.5 37.8 44.8 47.2 39.1 27.0 16.0 20.1 35.9 19.7 57.0 44.8 58.0 43.2 64.1 28.4 18.3 38.2 45.3 48.0 28.4 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 28.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.2;Proximal enterocytes: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.9;OE19: 18.0;RT4: 11.7;SK-BR-3: 13.3;T-47d: 14.4;U-266/84: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" 1.2 0.4 0.9 1.2 0.9 0.1 7.0 1.3 2.6 4.9 0.6 8.4 12.0 1.5 12.9 13.5 4.9 4.3 1.2 0.9 1.0 11.8 6.4 3.9 0.9 1.2 0.9 0.3 13.1 28.4 15.6 2.1 1.1 6.2 7.7 0.1 11.3 9.0 0.9 12.9 11.0 1.1 0.9 1.0 9.8 0.9 1.1 2.3 13.4 0.1 3.9 6.7 5.5 1.0 11.1 0.4 0.3 0.9 1.3 0.0 4.6 0.2 0.0 0.4 0.4 2.2 14.9 0.7 1.6 0.1 0.3 8.5 0.3 8.5 0.4 1.1 1.2 0.5 0.8 0.7 0.9 0.4 1.1 0.9 7.4 0.3 0.3 0.7 3.4 0.9 0.2 0.8 0.0 2.4 0.2 0.7 0.6 18.0 1.4 0.2 0.3 8.7 6.5 11.7 2.4 0.3 1.3 13.3 0.1 1.0 14.4 0.2 0.6 0.8 0.7 0.4 0.1 5.1 18.7 0.5 0.2 0.3 0.4 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.2 0.2 0.5 0.0 0.2 1.2 0.2 0.1 0.9 0.9 1.3 2.6 0.9 1.0 1.2 0.9 1.1 0.9 1.1 1.0 6.4 6.4 13.4 0.7 3.4 4.1 11.6 20.2 29.6 2.2 21.5 22.6 0.9 8.6 14.2 12.9 2.1 13.0 4.1 47.2 3.9 31.9 0.7 10.8 4.1 6.4 16.2 1.3 0.5 33.2 6.5 1.6 16.8 16.1 2.5 2.3 1.1 6.8 2.3 5.0 0.4 18.0 8.2 1.9 1.2 0.4 0.3 3.3 1.8 1.9 8.2 0.9 2.1 2.0 0.4 27.4 29.4 0.0 4.4 14.5 46.3 15.5 8.8 4.1 0.0 0.8 3.9 1.9 2.1 23.3 4.7 12.7 4.1 4.6 20.7 14.6 PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 4.8;Horizontal cells: 10.1;Inhibitory neurons: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 225.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" 16.3 1.3 3.2 0.4 2.7 57.7 8.5 3.2 2.9 2.5 0.7 1.3 0.1 0.5 0.0 2.7 1.1 0.7 1.5 2.0 6.3 0.1 0.4 0.9 0.1 4.7 4.8 1.1 0.3 0.3 0.2 0.0 4.0 0.4 0.2 1.0 1.1 0.8 4.5 2.3 1.2 0.4 3.6 2.1 2.1 0.4 5.1 0.6 0.5 4.5 0.0 0.5 3.0 2.1 0.0 0.1 0.3 0.5 1.3 0.1 3.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.2 8.8 0.1 1.3 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.0 2.6 46.6 1.2 0.0 0.1 12.9 0.6 1.0 0.0 0.1 0.5 225.3 0.4 0.2 0.3 1.5 0.1 6.1 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.2 2.9 2.0 6.3 4.7 4.8 4.0 3.6 5.1 2.1 0.4 0.0 0.0 1.0 0.0 0.6 0.1 0.2 0.6 4.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.2 10.1 12.6 0.0 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.8 1.2 0.3 0.3 0.1 0.0 0.0 0.1 PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 136.1;Oligodendrocyte precursor cells: 111.6;Oligodendrocytes: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cell line enhanced" "Detected in many" "CACO-2: 75.9;CAPAN-2: 94.3;HEL: 56.2" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" 5.4 22.2 21.7 4.5 28.7 0.9 7.6 24.9 27.2 12.9 16.1 9.9 17.7 15.8 7.4 5.5 9.8 14.8 10.9 22.4 24.6 4.8 2.8 4.3 4.2 26.7 24.0 20.2 4.6 13.4 11.4 2.9 28.0 7.8 11.3 16.5 9.7 8.2 1.3 1.8 17.1 9.8 25.8 3.2 17.5 2.2 23.7 6.8 5.3 2.8 3.2 7.4 6.3 37.1 19.5 41.3 30.2 12.4 4.9 24.4 0.0 20.2 15.1 14.2 19.3 75.9 94.3 0.0 3.1 23.7 1.2 10.7 34.7 0.0 22.0 0.0 1.4 56.2 7.6 0.1 14.6 0.0 0.0 7.1 0.2 7.7 0.0 13.3 22.6 2.2 18.6 10.5 6.8 0.5 8.8 0.1 20.9 3.3 0.7 9.7 0.1 0.2 12.7 0.5 21.5 0.9 19.3 0.1 0.0 0.6 1.1 4.3 12.2 6.3 15.5 23.1 12.2 0.9 0.0 0.0 16.8 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 4.4 0.0 0.1 0.0 0.9 21.7 28.7 24.9 27.2 22.4 24.6 26.7 24.0 28.0 25.8 23.7 37.1 3.5 0.0 0.5 136.1 0.7 2.7 4.6 5.4 2.8 10.2 1.1 5.8 8.6 7.2 3.9 3.7 2.1 1.0 0.8 3.8 5.9 5.8 1.4 1.5 27.3 2.8 5.4 3.0 38.2 0.5 4.9 20.6 12.2 2.2 0.0 25.1 7.5 0.1 7.2 6.7 43.0 7.3 0.0 0.9 3.1 1.0 12.2 7.8 3.6 24.4 1.5 45.8 0.0 111.6 148.2 2.3 2.1 9.8 1.3 1.1 12.2 0.1 1.1 15.9 0.0 16.4 10.4 3.4 6.3 0.4 2.8 0.8 1.0 22.7 11.6 1.5 PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4;thyroid gland: 10.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 191.8;Oligodendrocyte precursor cells: 51.8;Rod photoreceptor cells: 62.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "AF22: 148.6;SuSa: 172.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" 0.5 1.0 1.7 0.4 2.2 0.1 1.1 2.2 1.1 1.2 1.4 0.5 0.1 3.6 0.5 0.1 1.1 0.3 0.6 1.3 2.8 1.5 0.1 1.7 0.1 3.2 2.4 1.9 0.1 1.9 0.9 2.7 3.7 0.4 0.2 10.4 0.2 0.5 0.6 0.1 0.3 1.3 2.9 0.1 0.5 3.6 2.9 0.0 10.7 0.4 0.1 0.4 0.5 5.0 1.2 3.4 148.6 3.2 0.0 0.1 13.2 1.2 4.5 3.9 5.4 25.8 0.8 0.0 5.4 0.2 5.8 0.0 0.6 0.3 5.2 0.0 6.4 1.0 1.1 9.8 1.1 1.0 0.0 0.5 0.2 1.7 2.7 3.0 2.8 0.3 2.7 0.0 2.3 2.2 0.0 0.0 5.9 0.0 3.0 0.0 22.3 0.0 3.1 0.4 1.8 7.6 1.2 1.9 8.3 172.9 0.7 0.5 0.2 2.1 1.6 0.0 4.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 2.2 2.2 1.1 1.3 2.8 3.2 2.4 3.7 2.9 2.9 5.0 3.2 9.6 20.2 17.6 0.0 0.3 0.0 0.0 0.0 12.4 5.0 4.4 6.0 0.0 2.5 16.5 191.8 19.9 0.1 0.1 0.0 0.0 21.8 2.8 25.5 9.7 0.0 0.0 0.7 0.2 4.1 4.0 3.6 3.1 0.0 2.9 3.6 0.0 1.7 0.0 11.1 0.0 0.0 0.0 0.0 25.3 5.3 0.2 0.0 28.1 0.0 4.4 0.0 51.8 13.6 0.4 0.0 2.6 0.1 0.1 0.0 1.4 0.0 62.3 0.0 5.8 2.4 8.9 12.1 0.0 0.0 6.0 0.1 9.5 0.5 0.1 PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.6;intestine: 110.9" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 918.7" "Cancer enhanced" "Detected in many" "renal cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 51.1;LHCN-M2: 83.2;RH-30: 71.5;RPTEC TERT1: 40.1" "Low region specificity" "Detected in all" "HPA022470, HPA031079" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Nucleoplasm, Nucleoli" "HPA022470: AB_1845832, HPA031079: AB_10603230" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (2.43e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-2)" "unprognostic (9.79e-2)" "prognostic favorable (1.37e-6)" "unprognostic (7.75e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-3)" "unprognostic (3.80e-4)" 11.3 23.2 26.9 11.9 82.9 2.9 5.2 49.5 54.7 16.6 0.0 110.9 7.1 50.6 18.5 34.0 29.4 16.4 8.9 26.9 48.4 15.4 1.9 5.1 2.8 90.0 52.8 4.7 4.3 4.0 30.9 4.0 76.4 47.6 18.5 39.0 14.6 64.8 16.7 5.4 27.7 55.3 31.7 4.4 37.1 4.9 53.1 0.9 2.6 56.8 2.5 69.2 14.4 120.6 0.0 0.0 1.5 0.0 51.1 25.8 0.2 1.8 3.6 6.6 14.7 0.4 0.0 0.3 3.9 4.5 13.6 0.0 0.1 0.0 18.0 0.4 2.9 6.3 3.7 0.0 8.5 0.1 0.3 28.7 0.1 26.7 0.7 15.1 14.4 0.4 0.0 20.8 83.2 0.1 4.6 1.8 4.0 0.0 0.0 0.5 71.5 0.3 40.1 0.0 17.4 0.0 0.0 0.3 4.9 2.8 0.1 0.7 11.9 14.2 0.7 34.9 1.2 22.2 3.2 0.0 11.5 0.3 0.0 0.3 0.5 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.2 0.1 0.0 0.2 26.9 82.9 49.5 54.7 26.9 48.4 90.0 52.8 76.4 31.7 53.1 120.6 0.4 0.0 1.1 27.7 0.0 2.3 0.4 0.5 0.0 47.5 1.2 3.4 11.1 0.0 1.0 11.0 0.0 0.0 1.6 3.5 1.9 0.0 12.6 37.7 4.7 3.7 54.3 0.0 152.4 0.5 0.2 2.9 3.1 34.7 0.0 0.1 21.8 0.2 3.2 15.2 65.4 36.4 4.1 3.1 3.1 30.0 0.9 2.3 5.4 13.1 1.7 9.9 2.1 134.7 918.7 0.4 8.8 1.5 0.1 5.1 9.9 20.3 17.0 6.5 0.0 27.2 9.6 4.3 4.2 0.0 1.4 0.0 0.7 0.5 5.2 0.6 PRX KIAA1620 ENSG00000105227 Periaxin Q9BXM0 19 40393766-40414793 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 34.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.8;Breast myoepithelial cells: 23.2;Cardiomyocytes: 15.4;Skeletal myocytes: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 8 "spinal cord: 114.2" HPA001868 Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" "HPA001868: AB_2172440" "unprognostic (1.29e-2)" "unprognostic (3.04e-1)" "unprognostic (2.72e-2)" "unprognostic (9.72e-3)" "unprognostic (2.92e-1)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" "unprognostic (5.82e-2)" "unprognostic (3.23e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-2)" "unprognostic (2.03e-3)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (9.97e-2)" 4.5 4.7 6.2 1.3 6.8 1.6 3.9 5.2 6.5 4.8 2.9 3.6 1.1 4.4 1.0 2.0 4.2 1.8 3.1 4.7 4.4 6.7 1.0 34.6 1.3 5.4 4.9 6.2 3.8 5.9 1.5 5.1 6.7 4.6 0.7 0.8 3.8 3.5 4.9 3.2 2.2 2.0 4.9 2.0 3.7 1.6 5.7 0.7 9.6 5.5 0.8 4.3 3.1 4.1 1.6 2.6 2.1 2.7 1.3 4.4 2.6 1.4 1.5 1.9 1.4 1.0 1.7 0.5 1.6 1.3 1.2 0.9 1.0 0.6 0.7 0.8 0.9 0.3 0.3 0.5 2.1 0.1 2.3 3.3 3.2 1.2 1.1 1.7 1.6 2.9 2.0 0.5 1.0 2.2 1.0 0.6 0.6 3.8 1.7 3.2 1.8 1.5 0.4 1.8 0.2 1.0 2.7 2.3 2.0 0.9 3.2 1.2 1.4 3.8 2.9 1.6 0.8 5.3 5.0 0.7 1.1 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 6.2 6.8 5.2 6.5 4.7 4.4 5.4 4.9 6.7 4.9 5.7 4.1 17.8 3.2 5.9 0.7 1.4 6.2 2.3 0.3 5.7 0.1 8.1 23.2 15.4 2.8 0.9 1.8 0.0 1.1 1.7 1.0 0.0 0.3 0.1 1.3 1.7 9.2 0.0 0.4 0.6 0.6 0.7 7.0 0.0 3.0 0.0 2.0 6.8 1.3 1.1 0.0 0.5 0.7 2.0 1.6 2.5 0.1 3.4 2.5 3.6 7.5 0.3 3.3 0.0 0.0 0.5 0.5 1.4 4.5 0.9 1.7 1.2 1.9 0.2 0.1 0.0 30.3 6.1 0.3 0.7 5.0 4.1 2.7 1.1 1.3 1.5 1.0 PRY "PRY1, PTPN13LY" ENSG00000169789 "PTPN13 like Y-linked" O14603 Y 22490397-22514637 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059887 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nucleoli" Cytosol "HPA059887: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRY2 PTPN13LY2 ENSG00000169807 "PTPN13 like Y-linked 2" O14603 Y 22071756-22096007 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059887 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli" Cytosol "HPA059887: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRYP3 ENSG00000169763 "PTPN13 like Y-linked pseudogene 3" O14603 Y 23681440-23694579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 1.7;epididymis: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "A549: 4.5;HDLM-2: 7.7" HPA059887 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 44: HDLM-2 - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA059887: " 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.7 1.5 0.9 1.2 1.7 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PSD "EFA6, EFA6A, KIAA2011, PSD1, TYL" ENSG00000059915 "Pleckstrin and Sec7 domain containing" A5PKW4 10 102402617-102421539 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 233.9;intestine: 261.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.7;Cone photoreceptor cells: 95.9;Endometrial stromal cells: 47.7;Excitatory neurons: 41.1;Inhibitory neurons: 29.9;Rod photoreceptor cells: 70.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 7.7;MOLT-4: 4.4;SCLC-21H: 7.4;SH-SY5Y: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059237 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane, Cytosol" "HPA059237: AB_2683954" "unprognostic (2.43e-1)" "unprognostic (1.74e-1)" "unprognostic (5.62e-3)" "unprognostic (1.53e-1)" "unprognostic (3.16e-2)" "unprognostic (2.90e-2)" "unprognostic (7.73e-3)" "unprognostic (1.75e-1)" "unprognostic (9.59e-2)" "unprognostic (7.59e-2)" "unprognostic (2.24e-3)" "unprognostic (4.71e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (8.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" 1.2 9.1 159.5 3.8 151.7 0.7 1.5 7.8 233.9 53.8 0.0 261.8 6.1 78.3 1.4 1.6 46.2 8.9 4.4 220.9 63.9 2.8 2.4 1.2 0.9 23.8 25.4 15.3 5.0 1.5 99.4 0.8 27.3 4.3 3.5 36.8 1.0 1.2 0.4 1.6 41.4 17.7 14.9 1.5 44.2 12.4 70.2 1.4 1.1 0.0 0.4 105.7 14.7 87.6 0.2 0.0 3.0 2.7 1.1 0.6 0.3 0.2 0.0 0.1 0.0 2.1 0.3 0.2 1.8 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.1 1.6 0.0 0.1 7.7 0.2 0.5 0.1 1.2 0.0 1.0 0.4 0.7 0.0 1.7 4.4 0.2 0.4 0.3 0.0 1.2 0.0 0.1 0.0 0.1 7.4 6.4 0.1 0.1 0.2 0.2 0.5 0.4 0.0 2.2 3.5 0.2 0.0 1.9 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 159.5 151.7 7.8 233.9 220.9 63.9 23.8 25.4 27.3 14.9 70.2 87.6 0.7 3.2 0.5 6.8 1.0 0.6 0.3 0.3 0.0 50.7 1.1 0.5 1.5 2.8 1.5 0.0 95.9 0.2 0.6 0.8 1.9 0.2 6.6 4.8 47.7 1.0 18.0 0.0 41.1 1.9 0.2 4.0 2.6 1.8 0.0 0.4 0.0 1.3 0.7 13.5 29.9 0.9 0.0 0.6 0.7 2.7 3.7 0.5 0.0 3.7 0.1 13.2 0.0 9.0 2.4 0.7 1.4 4.1 0.1 0.4 1.3 1.2 0.5 70.8 0.0 2.0 1.1 4.0 3.7 0.7 0.1 0.7 1.9 8.8 1.3 0.1 PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4" "Cell type enhanced" "Detected in many" "Astrocytes: 558.3;Early spermatids: 686.7;Excitatory neurons: 284.7;Oligodendrocyte precursor cells: 488.1;Oligodendrocytes: 584.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.8;hTERT-RPE1: 48.0;LHCN-M2: 47.3;U-87 MG: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002455 Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA002455: AB_2666597" "unprognostic (3.87e-2)" "unprognostic (2.52e-2)" "prognostic favorable (7.55e-4)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.56e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.84e-2)" "unprognostic (7.27e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-3)" "unprognostic (2.13e-1)" "unprognostic (7.18e-3)" "unprognostic (3.71e-2)" "unprognostic (8.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" 2.4 17.8 24.8 3.1 46.2 1.2 5.9 62.4 46.1 11.9 0.0 6.7 4.8 8.8 3.8 5.3 2.5 7.4 27.5 51.9 4.0 1.9 18.9 4.6 2.5 3.3 10.0 18.0 9.9 18.4 7.3 6.6 1.8 3.9 7.3 19.9 4.1 5.8 1.3 4.4 5.0 5.8 0.0 10.4 9.8 16.4 7.8 2.2 6.1 2.3 3.4 5.8 4.3 17.2 11.0 5.7 25.0 0.1 8.8 53.8 1.3 5.7 8.9 5.1 10.5 3.3 4.3 6.5 3.6 23.8 22.3 0.9 7.3 10.1 9.7 0.0 6.6 0.6 4.6 0.5 15.9 0.2 0.4 14.2 6.2 28.2 4.9 48.0 6.8 1.6 0.8 4.9 47.3 3.7 0.0 1.2 4.9 9.6 14.7 5.2 21.4 3.0 12.7 14.0 10.7 11.8 2.5 1.1 3.8 5.4 0.3 2.6 28.0 15.7 10.8 37.5 5.1 0.4 0.7 14.8 49.5 2.7 5.4 0.7 0.2 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.5 0.1 0.1 0.3 0.3 0.2 0.1 0.4 0.1 24.8 46.2 62.4 46.1 51.9 4.0 3.3 10.0 1.8 0.0 7.8 17.2 8.1 3.2 2.7 558.3 3.3 21.9 13.7 26.4 13.6 191.9 14.4 10.7 119.2 7.2 23.9 9.2 118.9 3.2 0.1 48.5 1.9 13.5 686.7 12.5 69.9 8.2 6.1 0.0 284.7 8.7 1.7 44.3 43.8 6.6 0.0 87.2 4.2 42.9 13.1 18.5 121.6 20.0 44.7 16.0 25.9 217.9 33.2 9.0 1.8 148.9 59.7 78.0 0.0 488.1 584.6 27.0 13.5 53.8 0.1 11.2 20.3 0.3 41.0 52.0 13.1 29.3 17.7 16.5 17.7 32.4 9.9 1.1 1.1 114.9 17.2 23.7 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 395.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 25.1 22.6 44.3 26.5 80.7 39.6 28.2 62.4 56.0 28.1 48.9 49.5 50.2 25.3 26.9 35.2 22.9 31.7 18.0 47.4 51.6 35.5 31.9 32.1 22.4 73.0 63.8 22.0 22.9 35.1 11.6 43.1 71.5 24.3 46.3 23.4 22.9 23.4 18.4 38.2 49.0 27.1 55.7 22.6 31.0 32.5 60.8 26.2 36.9 23.3 30.7 35.0 19.2 119.1 37.1 55.9 50.6 20.0 68.9 49.9 46.7 52.5 60.1 52.6 66.7 69.9 88.9 23.7 34.1 50.5 43.0 94.9 43.2 40.1 57.3 54.6 26.7 27.1 35.1 34.4 63.8 27.7 50.7 50.4 71.9 44.3 54.4 48.5 43.2 26.2 31.0 46.6 50.0 72.8 21.0 35.7 22.0 64.5 40.4 26.4 42.7 30.2 73.7 76.5 28.1 38.3 57.4 53.0 47.1 45.4 66.3 60.7 45.7 53.1 43.5 44.1 25.3 30.3 47.9 23.7 44.9 32.8 33.3 126.8 94.5 96.3 23.1 106.0 22.6 23.1 22.3 19.0 83.4 31.8 20.7 20.1 129.3 42.8 125.0 43.6 37.0 70.3 44.3 80.7 62.4 56.0 47.4 51.6 73.0 63.8 71.5 55.7 60.8 119.1 22.2 28.9 30.5 35.9 25.8 28.6 24.6 24.7 12.0 17.1 25.0 17.7 12.5 15.7 30.2 23.9 39.6 27.1 30.7 79.1 5.9 27.1 22.9 26.3 26.4 22.3 16.2 12.0 38.9 26.7 29.2 23.7 32.1 47.4 18.3 29.6 15.7 24.6 30.5 13.5 40.2 39.5 24.4 50.5 40.8 12.9 16.4 52.3 16.0 39.4 51.8 13.8 14.4 48.7 395.8 38.2 58.8 15.4 23.6 38.8 76.2 13.0 29.0 28.0 26.3 20.0 19.0 40.2 14.4 20.4 33.0 49.9 21.6 18.6 41.3 51.5 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86047109-86088621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "retina: 2.4" "Cell type enhanced" "Detected in single" "Rod photoreceptor cells: 2.1" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HEL: 9.4" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PSMA1 "HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30" ENSG00000129084 "Proteasome 20S subunit alpha 1" P25786 11 14504874-14643635 "Enzymes, Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 627.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033765, HPA037646, HPA043891, CAB079995" Supported Supported "Nucleoplasm,Nuclear bodies,Centrosome" NA NA 20000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Nuclear bodies, Centrosome" "CAB033765: AB_2253026, CAB079995: , HPA037646: AB_10670386, HPA043891: AB_2678718" "unprognostic (1.72e-2)" "unprognostic (4.97e-2)" "unprognostic (7.33e-2)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (6.66e-3)" "prognostic unfavorable (3.79e-5)" "unprognostic (3.28e-3)" "unprognostic (7.44e-2)" "unprognostic (3.43e-3)" "unprognostic (8.27e-3)" "unprognostic (8.77e-2)" "prognostic unfavorable (4.03e-11)" "unprognostic (1.93e-1)" "unprognostic (1.69e-1)" "unprognostic (4.66e-2)" "unprognostic (1.23e-2)" 87.2 85.5 55.1 94.9 57.8 135.8 96.2 55.4 68.2 76.8 58.7 92.5 96.4 80.7 108.0 94.7 79.4 79.6 140.5 59.4 64.4 98.4 139.2 77.5 114.9 55.8 56.6 79.4 54.6 78.5 50.4 113.0 58.8 81.7 101.9 63.2 74.4 85.8 168.7 80.5 86.1 96.1 56.6 75.6 75.7 56.2 60.2 122.2 88.4 152.6 109.9 111.2 56.0 58.6 408.8 279.8 227.8 275.7 223.7 225.5 193.3 232.9 305.2 348.3 283.9 244.2 500.1 349.5 262.1 248.6 315.4 303.1 259.3 290.1 328.3 344.0 389.6 220.4 190.5 326.1 291.0 355.3 277.5 217.8 171.6 188.9 390.7 252.7 347.0 271.6 398.9 283.4 315.2 277.8 334.0 319.5 191.6 340.5 414.1 223.3 336.1 217.5 313.0 304.7 188.2 119.3 246.6 273.9 229.0 233.8 164.4 222.9 272.0 226.2 222.9 402.7 295.4 123.3 366.1 319.9 334.8 291.1 296.6 115.5 191.2 47.5 97.7 139.8 128.0 104.1 110.8 109.7 243.3 95.3 98.5 94.4 36.3 145.1 137.5 138.7 154.9 235.8 55.1 57.8 55.4 68.2 59.4 64.4 55.8 56.6 58.8 56.6 60.2 58.6 119.0 83.3 90.2 64.3 101.7 142.9 231.2 365.7 76.2 50.3 105.7 125.9 0.0 82.9 176.1 88.3 18.8 469.5 135.3 49.2 256.3 228.5 75.5 84.0 94.0 135.5 40.1 163.9 56.8 233.1 370.6 128.5 66.8 79.8 78.2 134.7 95.3 127.9 292.9 57.2 66.3 63.6 231.9 161.8 170.5 36.3 116.5 153.6 144.1 122.7 263.7 111.6 168.9 64.8 35.3 223.2 88.6 127.5 112.1 209.1 135.0 257.1 115.1 54.8 85.5 99.2 129.8 174.9 80.1 114.3 151.9 627.3 130.7 137.2 97.1 248.1 PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome 20S subunit alpha 4" P25789 15 78540405-78552417 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported Nucleoplasm,Vesicles,Cytosol No No 13000000 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" Vesicles "CAB004973: AB_425627, HPA055466: AB_2682824, HPA060613: AB_2684332" "unprognostic (1.80e-1)" "unprognostic (7.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.71e-2)" "unprognostic (5.35e-2)" "unprognostic (6.26e-3)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "unprognostic (2.08e-3)" "unprognostic (2.75e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (6.74e-10)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.78e-3)" "unprognostic (6.32e-3)" 92.9 105.0 62.5 106.3 64.4 107.6 87.5 66.2 98.8 78.9 65.6 105.1 108.9 89.6 74.5 118.2 71.6 66.0 108.4 64.7 69.1 98.1 152.1 87.9 136.9 67.6 65.5 64.6 67.3 73.4 54.4 85.8 67.5 97.2 109.6 50.3 70.3 64.2 180.6 78.3 101.3 99.3 69.3 115.3 88.5 109.9 65.6 156.5 70.6 121.6 128.7 118.8 81.2 69.9 274.2 386.9 327.7 290.8 202.1 189.5 256.3 250.2 199.9 301.4 320.6 404.9 386.9 590.8 359.7 232.5 337.4 363.9 669.1 271.8 289.1 244.2 465.7 497.6 271.6 330.1 326.9 512.6 294.5 154.6 166.8 255.0 250.9 185.4 330.7 319.1 544.2 225.0 249.6 392.3 347.5 477.4 309.7 315.3 224.5 297.7 432.9 198.9 309.5 469.4 287.6 209.9 401.3 289.5 327.5 402.2 267.8 414.7 265.8 223.7 298.6 249.3 434.2 204.0 517.9 556.2 209.9 756.7 252.6 126.0 251.9 172.9 136.2 403.9 140.3 156.0 142.0 144.7 327.4 119.9 111.7 137.0 112.8 209.4 394.8 185.4 216.8 405.6 62.5 64.4 66.2 98.8 64.7 69.1 67.6 65.5 67.5 69.3 65.6 69.9 119.0 128.2 118.5 17.3 124.1 231.6 269.6 765.7 84.2 57.8 88.5 95.8 163.7 105.8 327.0 121.4 10.4 478.9 128.4 145.3 311.0 296.2 689.4 158.0 183.6 162.5 146.2 153.2 18.0 292.7 450.6 159.9 78.0 126.0 174.2 152.9 114.9 178.9 320.4 72.3 19.6 216.2 506.6 143.2 201.7 399.0 151.0 176.9 133.4 23.4 308.6 63.5 149.3 11.1 21.5 256.0 165.7 147.4 108.0 249.3 195.8 367.2 280.0 39.8 151.2 95.4 241.1 417.1 181.0 106.4 212.8 447.1 128.6 166.7 234.7 258.4 PSMB7 Z ENSG00000136930 "Proteasome 20S subunit beta 7" Q99436 9 124353465-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No 2100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA052408: AB_2681820, HPA054902: AB_2682635" "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" 115.7 180.4 129.4 103.9 136.9 189.7 122.6 132.7 144.8 99.8 119.6 103.5 98.7 102.9 147.0 139.1 94.6 87.2 212.0 135.8 137.0 150.9 222.9 91.4 112.7 138.2 139.5 101.6 142.2 143.4 74.7 120.2 138.2 94.8 107.8 81.0 114.3 75.0 277.8 166.2 98.3 92.7 131.5 91.7 115.3 155.2 137.8 147.6 91.3 205.3 124.6 110.5 104.2 135.0 344.4 411.7 275.8 336.4 190.4 224.8 396.1 325.3 447.6 461.7 315.1 546.3 327.1 389.2 256.8 307.4 457.2 480.2 346.7 345.4 420.0 375.0 299.3 245.3 673.3 460.0 428.5 491.6 234.3 270.8 299.6 483.7 478.5 355.1 394.3 345.5 507.9 269.8 362.4 600.0 355.9 329.5 409.7 519.6 581.5 309.8 411.4 457.2 331.5 221.9 323.7 263.6 310.4 394.0 498.4 268.7 454.8 212.7 315.9 297.5 240.7 384.9 499.0 289.9 873.7 394.9 498.1 297.8 429.1 162.7 201.5 154.5 128.3 211.4 138.9 177.8 145.7 142.5 221.1 159.7 138.2 135.9 87.0 185.3 206.8 187.5 226.0 264.8 129.4 136.9 132.7 144.8 135.8 137.0 138.2 139.5 138.2 131.5 137.8 135.0 73.1 76.9 77.6 26.1 88.0 194.1 184.4 309.1 39.9 41.5 113.9 97.5 147.3 134.4 150.0 69.9 22.9 441.4 83.0 146.9 330.6 351.3 404.6 105.7 93.8 123.8 141.2 93.8 38.4 392.7 356.7 112.3 52.5 90.3 104.6 130.8 107.1 277.3 237.2 33.7 31.9 162.5 160.7 122.1 148.4 472.8 139.1 92.5 199.3 33.7 168.5 119.7 113.3 30.7 44.8 393.6 143.7 125.3 69.9 158.0 173.6 484.7 135.7 61.6 85.5 133.8 221.2 330.6 190.4 60.4 218.9 488.7 81.4 135.8 181.2 201.3 PSMC3 "TBP-1, TBP1" ENSG00000165916 "Proteasome 26S subunit, ATPase 3" P17980 11 47418769-47426473 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006065 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA006065: AB_1079706" "unprognostic (2.01e-2)" "unprognostic (5.08e-3)" "unprognostic (9.43e-2)" "unprognostic (8.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.71e-2)" "unprognostic (8.99e-3)" "unprognostic (1.63e-1)" "unprognostic (9.95e-2)" "unprognostic (1.27e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" 85.3 86.1 106.8 64.7 117.3 96.1 77.9 105.3 131.0 73.7 105.8 110.2 52.2 89.9 62.5 88.7 69.0 44.0 172.1 107.8 106.3 73.8 117.7 76.2 65.3 108.6 114.7 58.2 81.4 74.1 55.4 78.8 111.0 74.2 59.1 30.9 73.0 69.8 292.0 103.4 64.0 77.5 104.6 67.8 87.7 74.7 115.2 90.6 69.4 162.9 76.5 80.8 71.7 107.0 223.7 248.2 233.5 173.3 109.6 117.3 226.5 181.5 267.4 445.7 313.8 223.3 126.8 179.5 110.1 230.1 195.7 218.3 206.7 237.7 199.0 269.4 268.1 173.1 301.1 218.5 141.4 203.7 177.0 131.4 126.1 181.6 202.5 98.4 253.8 182.7 249.2 164.7 276.0 497.0 259.5 258.4 229.5 280.7 296.1 269.3 458.8 157.3 209.5 165.2 170.0 147.1 148.7 206.9 116.2 98.2 255.7 209.8 181.3 253.7 321.1 363.8 474.7 176.5 220.0 209.2 262.4 201.7 325.1 111.5 154.3 121.8 160.8 194.6 146.7 146.8 132.9 147.8 160.6 122.4 116.5 118.6 33.9 173.3 211.6 160.0 191.0 254.7 106.8 117.3 105.3 131.0 107.8 106.3 108.6 114.7 111.0 104.6 115.2 107.0 81.5 57.7 42.0 3.9 59.5 86.3 112.8 198.5 50.7 41.2 61.4 64.1 217.6 81.5 103.7 68.0 16.7 265.9 60.0 143.9 152.6 199.2 152.5 72.0 75.7 96.0 64.5 136.6 6.4 202.6 257.9 100.4 54.0 70.1 75.3 79.2 77.1 144.2 158.2 37.0 5.3 111.5 75.3 62.4 80.0 217.6 88.6 62.5 99.6 1.9 132.0 120.2 74.2 3.0 5.2 214.2 110.8 100.1 96.3 102.8 127.7 191.3 76.9 47.4 118.3 75.1 193.3 147.0 63.6 51.3 77.3 352.9 61.8 74.1 117.6 101.6 PSMC6 p42 ENSG00000100519 "Proteasome 26S subunit, ATPase 6" P62333 14 52707178-52728590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042823 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042823: AB_2678188" "unprognostic (2.38e-2)" "unprognostic (2.72e-2)" "unprognostic (9.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-2)" "unprognostic (4.26e-3)" "unprognostic (3.14e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (2.79e-2)" "unprognostic (3.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.52e-2)" "unprognostic (5.00e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (4.67e-1)" 43.4 48.4 38.8 47.3 39.2 44.1 58.1 41.2 54.0 44.0 37.4 52.2 50.0 47.6 49.2 65.1 49.2 36.5 78.7 39.8 42.1 65.9 87.1 39.6 55.4 41.1 41.0 51.0 43.7 59.9 5.5 54.9 42.0 45.3 54.3 60.1 37.9 45.6 118.1 44.6 46.6 56.8 41.5 38.8 46.5 31.4 41.0 56.3 54.3 106.7 67.0 57.2 7.9 44.1 182.0 115.0 135.4 99.0 92.4 95.8 146.0 139.3 133.1 220.8 165.1 142.6 143.5 156.8 169.8 121.6 111.5 134.0 173.9 121.9 230.6 151.2 74.5 115.0 91.3 153.5 111.0 164.9 106.8 71.8 118.4 112.1 111.6 120.1 141.2 77.4 174.2 64.7 161.8 163.2 129.5 111.8 108.7 170.1 153.8 108.4 237.2 70.7 144.6 178.5 96.0 71.2 123.8 76.5 122.3 120.8 156.4 117.0 108.9 121.2 171.0 95.8 145.2 45.6 127.0 175.8 79.1 110.5 112.9 77.5 62.4 67.0 51.2 71.9 59.5 63.4 62.7 56.4 73.9 56.4 59.6 59.0 52.7 55.6 73.0 38.5 85.4 75.4 38.8 39.2 41.2 54.0 39.8 42.1 41.1 41.0 42.0 41.5 41.0 44.1 81.2 70.5 58.9 23.5 74.2 86.2 141.9 187.1 50.1 65.5 55.3 51.3 76.6 62.9 140.6 57.0 68.8 162.2 69.4 73.5 135.0 131.0 30.4 92.8 75.3 78.2 70.4 85.2 37.4 106.9 139.9 72.1 38.7 96.3 67.7 68.7 50.0 84.4 92.1 62.2 39.0 58.9 109.9 71.3 67.9 19.9 67.1 61.4 80.0 20.6 90.9 64.6 52.5 38.2 46.7 116.2 46.2 65.5 64.0 85.2 72.5 140.2 116.4 107.6 72.3 66.5 130.6 63.4 82.8 48.9 72.0 237.5 65.0 79.7 73.4 116.6 PSMD12 "p55, Rpn5" ENSG00000197170 "Proteasome 26S subunit, non-ATPase 12" O00232 17 67337916-67366605 "Disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023119 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA 73000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Nucleoplasm, Cytosol" "HPA023119: AB_1855845" "unprognostic (6.06e-2)" "unprognostic (3.16e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.35e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.28e-2)" "unprognostic (3.72e-2)" "prognostic favorable (6.32e-4)" "unprognostic (2.63e-1)" "unprognostic (7.32e-3)" "prognostic unfavorable (4.73e-6)" "unprognostic (1.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" 14.8 13.9 11.2 11.4 12.2 12.5 11.9 15.0 19.4 9.4 9.7 10.4 8.2 10.5 10.9 12.5 7.6 9.7 13.7 12.6 17.2 14.9 28.0 9.4 10.8 17.8 17.8 9.1 15.6 14.8 7.6 11.0 18.9 10.7 11.6 8.9 10.0 7.7 35.8 10.3 8.7 11.3 12.9 9.4 11.2 14.4 16.0 12.1 10.3 29.1 15.1 14.7 8.0 12.5 63.8 38.5 29.2 32.2 21.9 26.3 40.6 44.2 27.9 47.8 42.0 40.4 27.4 36.6 28.0 35.9 37.4 37.0 51.1 45.1 70.7 17.8 38.5 43.2 29.9 41.1 28.6 44.7 25.0 29.6 29.4 45.3 35.2 21.2 47.6 27.8 57.4 21.0 45.0 43.5 41.0 42.6 35.7 30.0 50.1 20.9 75.6 32.5 36.1 52.0 28.0 40.6 32.9 62.6 45.2 34.1 45.0 36.9 49.5 50.5 34.4 38.6 81.4 21.4 35.2 30.5 59.8 46.5 29.9 14.0 9.9 8.9 8.7 16.7 12.3 8.0 11.5 9.9 10.3 8.9 10.1 10.7 7.3 10.9 19.6 7.0 12.1 8.7 11.2 12.2 15.0 19.4 12.6 17.2 17.8 17.8 18.9 12.9 16.0 12.5 59.6 48.1 58.8 9.8 37.9 112.3 119.5 109.0 43.3 40.8 37.9 33.0 108.1 25.8 97.7 46.0 25.0 88.3 47.9 29.7 70.5 80.7 158.1 99.1 62.3 73.8 32.9 67.3 21.0 78.7 88.8 64.0 33.1 125.3 50.6 39.9 41.0 84.1 56.0 92.5 22.0 28.6 65.1 44.7 90.6 197.0 46.3 50.6 48.0 10.3 59.8 58.6 37.0 14.6 15.0 84.9 22.7 44.0 58.2 93.4 26.0 77.2 68.1 44.6 26.3 78.6 146.8 126.2 108.0 52.9 94.8 123.0 53.8 53.8 34.1 123.2 PSMG1 "c21-LRP, DSCR2, LRPC21, PAC1" ENSG00000183527 "Proteasome assembly chaperone 1" O95456 21 39174769-39183488 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.3" "Group enriched" "Detected in all" 4 "Early spermatids: 673.8;Spermatocytes: 544.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057193, HPA070225" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA057193: AB_2683363, HPA070225: AB_2686236" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (2.10e-1)" "unprognostic (9.38e-2)" "unprognostic (5.06e-3)" "unprognostic (2.02e-1)" "unprognostic (1.66e-2)" "unprognostic (5.09e-2)" "unprognostic (1.09e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.84e-1)" "unprognostic (8.98e-2)" "unprognostic (1.32e-2)" "unprognostic (4.17e-3)" 7.5 9.8 4.0 9.1 4.0 17.3 6.8 2.7 5.5 7.3 2.5 10.5 8.9 7.8 4.8 11.8 6.4 5.4 8.3 4.6 3.8 9.7 15.9 5.7 8.9 2.2 2.4 7.2 10.8 5.1 8.0 7.7 3.2 5.5 9.9 4.9 7.3 3.2 13.8 7.1 8.2 5.1 2.1 6.3 7.1 40.3 3.7 6.3 10.8 5.6 6.2 7.8 7.4 4.0 104.0 34.7 23.5 32.9 12.3 15.1 65.0 55.3 25.9 44.8 28.2 66.6 26.9 113.7 28.9 17.1 38.1 28.5 40.3 30.3 30.2 48.9 61.6 209.6 52.4 83.6 21.9 101.0 40.4 18.9 24.6 46.2 46.5 9.8 24.9 47.0 160.4 61.9 27.2 58.2 63.0 54.7 82.2 38.9 53.5 99.6 29.8 115.8 19.1 30.4 77.6 22.7 70.4 39.1 57.4 4.0 36.6 51.4 26.7 50.1 16.8 66.7 79.9 46.4 79.3 96.8 42.0 170.4 38.6 10.6 6.8 3.9 10.5 9.0 12.3 12.0 14.7 12.4 12.2 10.6 11.5 10.3 0.6 7.5 9.1 11.3 13.7 7.9 4.0 4.0 2.7 5.5 4.6 3.8 2.2 2.4 3.2 2.1 3.7 4.0 23.7 6.4 17.6 5.2 17.8 136.0 44.1 68.6 43.9 14.2 31.3 39.0 24.8 22.8 39.9 20.2 4.2 108.9 12.6 14.7 66.5 50.8 673.8 20.8 36.5 26.3 29.9 63.3 7.5 49.7 118.6 31.8 18.8 21.6 36.1 26.2 18.9 32.7 59.5 8.4 8.0 45.7 69.2 17.7 35.5 88.4 31.7 25.0 46.2 3.7 24.4 18.0 12.3 3.5 5.9 32.4 20.0 33.1 31.7 41.5 30.6 89.4 20.8 19.7 26.3 29.5 31.3 544.1 98.7 51.7 97.7 54.5 20.1 54.7 56.9 27.9 PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 31.3;Spermatocytes: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: AB_2675662, HPA037781: AB_10670530" "unprognostic (8.95e-3)" "unprognostic (5.51e-3)" "unprognostic (1.37e-1)" "unprognostic (7.39e-4)" "unprognostic (5.21e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-2)" "unprognostic (5.92e-4)" "unprognostic (3.55e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-3)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "unprognostic (4.50e-2)" "unprognostic (4.92e-2)" "unprognostic (3.02e-2)" "unprognostic (5.55e-4)" 0.9 2.2 1.3 0.6 1.5 6.1 2.9 1.5 2.2 1.9 0.3 1.6 1.9 1.9 3.5 1.5 1.9 0.7 1.7 1.5 1.6 2.0 4.1 1.0 0.9 1.6 1.5 1.3 2.1 1.1 2.6 1.3 2.5 2.0 1.5 0.5 1.9 1.1 3.5 1.6 1.0 1.9 1.3 1.1 1.3 3.2 1.4 1.8 2.4 0.9 1.2 1.3 1.3 2.8 4.1 3.4 1.7 0.8 1.6 3.2 2.1 2.0 3.5 3.0 3.7 4.6 3.4 4.4 3.9 2.5 2.0 2.3 0.7 3.1 3.4 2.4 8.7 2.7 1.2 4.0 4.3 6.7 3.6 3.3 5.2 2.9 5.2 2.7 2.3 3.9 4.3 6.0 4.3 6.6 2.0 3.9 3.3 1.6 4.3 4.5 3.0 4.4 4.3 2.6 1.6 2.1 3.9 3.8 5.3 1.4 1.8 0.4 3.1 2.8 2.6 1.2 4.5 2.6 1.6 5.8 2.4 4.3 0.9 0.0 5.0 6.0 7.4 3.1 8.8 6.2 5.7 7.0 6.7 5.9 7.5 7.7 0.6 6.8 3.6 6.7 3.8 5.3 1.3 1.5 1.5 2.2 1.5 1.6 1.6 1.5 2.5 1.3 1.4 2.8 3.0 9.6 7.3 14.4 4.6 4.5 5.0 11.0 5.2 8.3 7.1 11.7 5.9 10.0 7.5 5.5 8.4 7.7 8.0 1.6 9.8 4.6 31.3 5.7 5.2 3.2 4.2 3.4 18.8 6.3 3.1 6.0 1.5 11.6 2.5 8.1 3.6 6.3 4.8 5.0 20.3 2.6 14.2 2.1 4.3 5.4 5.3 3.0 5.4 4.7 6.1 8.8 5.2 12.5 29.4 3.7 3.8 5.7 3.3 3.5 3.0 7.7 8.3 11.4 0.0 5.6 8.6 37.5 20.6 5.5 4.7 9.6 6.9 10.8 4.3 3.5 PSTPIP2 ENSG00000152229 "Proline-serine-threonine phosphatase interacting protein 2" Q9H939 18 45983536-46072272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 72.4;lymphoid tissue: 63.4;skeletal muscle: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 44.6;Erythroid cells: 46.7;Macrophages: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 112.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 102.0;HMC-1: 108.3" "Low region specificity" "Detected in all" "HPA040923, HPA040944" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" No No 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Mitochondria" Nucleoplasm "HPA040923: AB_10794429, HPA040944: AB_10795485" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-2)" "unprognostic (4.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (5.83e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (5.21e-2)" "unprognostic (3.55e-1)" "unprognostic (1.61e-1)" "unprognostic (1.93e-1)" 4.4 4.6 0.9 11.1 0.9 72.4 8.5 0.8 1.5 4.2 1.8 4.4 3.6 2.9 1.4 5.1 4.0 5.3 2.1 0.8 1.1 3.7 10.0 11.4 6.3 1.8 1.2 3.6 3.5 3.8 2.9 12.1 1.5 8.0 5.1 2.8 5.9 2.7 33.0 8.8 4.5 4.6 1.1 63.4 6.4 1.3 1.2 3.9 2.1 5.8 4.9 9.6 4.3 1.4 2.9 0.0 3.8 0.1 0.9 6.7 20.6 15.0 7.4 5.3 4.5 11.6 4.0 0.1 0.9 5.0 0.0 36.2 20.3 28.1 6.6 0.0 3.2 102.0 4.6 0.2 5.9 6.0 108.3 5.0 34.4 5.0 16.3 4.8 10.6 0.2 24.8 0.1 23.1 3.6 0.9 0.1 2.3 0.0 0.1 0.1 7.5 4.9 11.2 37.0 0.3 2.1 2.4 10.3 0.5 28.2 32.6 12.0 7.6 0.6 8.2 0.8 0.2 0.1 0.3 0.1 1.3 0.2 0.4 77.3 25.3 112.8 10.4 35.0 3.6 0.1 6.2 7.7 25.3 0.1 7.2 8.8 13.5 2.9 36.4 0.9 4.1 20.0 0.9 0.9 0.8 1.5 0.8 1.1 1.8 1.2 1.5 1.1 1.2 1.4 1.7 12.8 11.6 0.7 2.4 13.8 19.4 44.6 15.4 0.7 11.1 17.1 3.5 2.8 24.9 0.0 0.0 26.6 21.8 0.6 3.9 9.6 2.0 4.1 2.6 3.1 1.2 46.7 1.6 3.9 3.3 4.2 11.2 11.2 43.6 20.6 7.1 17.3 14.6 0.0 1.4 4.2 6.1 42.5 5.5 7.3 2.8 58.7 7.2 2.8 37.4 10.9 25.7 2.0 0.9 17.7 0.3 2.2 3.6 39.7 0.5 4.1 13.0 0.4 6.6 3.1 7.7 1.1 1.6 7.3 10.2 8.8 17.8 7.1 2.4 21.8 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "granulocytes: 75.4;Hofbauer cells: 71.7;Kupffer cells: 93.0;Langerhans cells: 67.8;Macrophages: 64.5;monocytes: 52.8;Pancreatic endocrine cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.7;eosinophil: 906.5;neutrophil: 747.1" "Group enriched" "Detected in many" 5 "granulocytes: 906.5;monocytes: 256.7" "Group enriched" "Detected in some" 4 "HBEC3-KT: 36.6;HMC-1: 131.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 10.4 2.4 4.3 30.8 4.7 41.1 3.4 4.7 5.6 3.4 4.1 5.5 4.1 1.7 1.2 7.2 2.6 7.2 2.0 3.8 5.1 2.7 4.1 17.8 13.5 8.9 6.6 1.3 2.0 1.6 0.6 7.3 7.7 1.5 6.7 0.5 2.3 1.5 0.7 5.4 6.3 7.9 8.1 14.4 3.8 1.3 7.2 3.6 1.9 2.6 18.0 14.4 1.9 11.8 20.1 0.2 0.1 0.4 0.2 0.0 0.5 0.0 0.0 0.7 0.2 0.2 5.7 1.3 0.1 0.1 0.3 13.5 0.5 36.6 0.8 0.4 0.6 7.7 0.2 0.9 0.1 1.9 131.3 0.0 6.0 0.4 0.4 0.0 0.2 0.1 0.5 0.4 0.0 1.3 0.2 19.3 0.6 0.5 0.2 0.3 0.1 0.1 8.7 2.1 0.3 0.1 0.1 18.1 0.2 0.4 0.4 5.4 0.1 0.2 0.7 0.0 0.2 1.2 1.1 5.6 0.1 2.4 0.6 61.7 256.7 906.5 0.6 77.9 1.2 12.5 0.4 0.4 116.1 6.7 0.5 0.7 747.1 0.7 34.1 1.3 1.2 112.4 4.3 4.7 4.7 5.6 3.8 5.1 8.9 6.6 7.7 8.1 7.2 11.8 2.1 6.4 6.7 0.0 4.1 6.5 2.0 37.9 5.2 1.5 0.8 0.5 2.2 1.5 20.9 1.8 2.1 0.6 2.9 0.4 0.0 18.1 0.4 0.5 0.2 7.3 0.0 4.0 0.9 5.1 0.5 1.3 1.1 0.5 75.4 2.0 2.9 1.0 71.7 0.0 0.7 0.0 18.3 93.0 67.8 0.2 0.6 64.5 0.0 15.0 52.8 0.2 0.0 1.5 6.6 89.8 0.6 0.0 0.5 0.6 0.3 0.2 20.2 0.9 0.0 0.6 1.0 2.3 0.7 3.2 2.8 1.5 2.0 0.0 0.4 9.4 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTMS ParaT ENSG00000159335 Parathymosin P20962 12 6765516-6770952 "Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 565.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 25.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 25.6" "Cell line enhanced" "Detected in all" "HDLM-2: 672.8" HPA038186 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes 300000 "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA038186: AB_10673042" "unprognostic (3.11e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (3.57e-2)" "unprognostic (1.09e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (2.47e-1)" "unprognostic (4.16e-1)" "unprognostic (1.01e-1)" "unprognostic (8.69e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (3.21e-1)" "unprognostic (2.35e-3)" "unprognostic (1.55e-2)" 138.4 78.4 115.9 37.0 105.9 14.3 121.4 103.2 122.3 188.2 48.6 293.9 33.0 243.9 29.0 128.0 145.3 28.9 98.7 117.0 74.3 186.6 565.2 173.5 22.7 45.9 43.5 239.9 50.3 82.4 96.3 49.4 48.0 194.3 28.9 64.6 94.4 86.8 56.3 116.8 101.1 98.8 31.6 61.4 109.5 32.6 86.0 16.3 109.5 16.2 20.1 176.6 137.5 72.5 49.2 250.8 324.8 320.3 149.8 126.2 127.5 210.9 189.2 157.6 130.1 153.8 190.2 19.5 151.8 321.7 143.2 104.6 178.7 159.3 61.9 672.8 219.1 27.5 160.6 58.1 174.1 7.7 56.6 123.7 68.8 121.4 245.6 237.7 175.3 8.6 175.5 50.6 139.8 144.1 9.2 40.7 347.6 92.2 180.8 4.2 99.8 39.6 124.7 12.5 107.4 363.6 254.7 86.9 186.1 230.0 75.9 23.4 296.7 239.6 344.2 36.6 195.2 42.4 19.3 25.4 196.5 18.1 183.6 25.6 0.4 3.6 1.3 0.1 0.6 0.1 0.1 1.1 0.3 0.0 0.0 0.1 1.3 0.1 0.0 4.4 0.5 0.4 115.9 105.9 103.2 122.3 117.0 74.3 45.9 43.5 48.0 31.6 86.0 72.5 370.5 0.0 14.1 9.4 22.8 289.5 328.0 44.6 257.8 325.5 239.2 275.5 10.4 88.6 16.7 154.5 200.1 153.6 88.4 99.8 234.8 61.9 6.6 73.1 494.8 342.7 513.3 248.6 28.7 34.0 404.0 292.4 66.3 117.5 52.8 216.3 325.2 710.0 491.3 116.1 15.2 229.4 22.4 100.4 309.4 23.1 489.6 136.8 227.7 12.2 76.7 512.6 4.1 13.0 3.1 38.3 141.3 692.1 38.8 399.9 244.2 547.6 11.4 357.7 598.2 232.0 411.7 7.4 32.8 259.4 249.2 163.2 81.3 122.5 198.9 206.7 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" Vesicles "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favorable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 18.5 19.1 6.2 12.6 9.2 14.7 17.4 5.8 10.5 23.3 5.1 16.3 14.3 20.9 7.5 19.0 19.2 8.4 13.2 7.1 7.2 17.5 14.0 18.7 9.1 8.8 7.2 23.5 20.2 23.5 30.9 11.6 8.5 18.7 6.5 8.5 20.0 11.4 30.0 26.4 18.4 8.8 5.5 20.0 16.1 15.6 7.7 8.0 27.1 8.9 7.3 18.5 20.4 14.4 21.5 29.9 16.4 21.4 21.0 16.0 15.8 19.2 18.9 17.5 14.8 25.0 20.7 15.1 17.2 21.9 31.2 19.0 14.3 20.8 8.5 14.3 15.1 21.0 22.2 24.0 23.0 12.3 27.5 21.4 20.9 22.9 23.2 12.4 21.7 12.5 15.9 20.3 19.0 30.2 11.5 10.4 17.5 14.9 20.1 7.2 7.9 18.5 13.2 40.9 8.6 20.6 17.1 35.6 13.6 9.8 20.3 12.0 22.4 26.7 22.2 37.7 27.5 28.8 20.4 8.7 29.0 11.6 19.5 0.8 0.2 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.3 0.3 6.2 9.2 5.8 10.5 7.1 7.2 8.8 7.2 8.5 5.5 7.7 14.4 11.1 9.6 7.0 17.0 8.2 8.0 5.2 6.9 13.6 11.7 9.5 8.0 8.7 8.6 9.5 5.5 14.6 10.6 11.0 15.7 1.9 10.5 2.1 10.3 13.7 12.4 7.3 2.5 9.8 8.9 7.9 9.1 26.5 21.1 2.5 14.9 11.4 12.7 13.9 16.8 12.0 16.3 20.3 10.4 5.5 3.1 19.3 9.5 12.4 7.5 8.7 8.8 6.2 9.5 14.3 13.5 10.4 13.5 15.4 9.3 14.6 9.4 12.6 14.2 6.6 10.2 8.8 13.6 13.3 13.2 10.9 9.3 8.9 9.4 12.8 8.2 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase non-receptor type 4" P29074 2 119759922-119984899 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 224.3;Horizontal cells: 161.5;Inhibitory neurons: 187.5;NK-cells: 247.2;Oligodendrocyte precursor cells: 200.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 37.3" "Group enriched" "Detected in many" 4 "gdT-cell: 35.0;MAIT T-cell: 28.1;memory CD4 T-cell: 16.9;memory CD8 T-cell: 27.9;naive CD8 T-cell: 19.2;NK-cell: 24.4;T-reg: 11.0" "Group enriched" "Detected in many" 16 "NK-cells: 24.4;T-cells: 35.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favorable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 4.5 3.8 5.9 3.6 5.0 5.1 4.7 37.3 10.1 5.7 0.0 3.4 5.1 4.1 4.2 4.1 5.5 3.7 5.7 5.2 2.7 7.4 4.2 5.2 5.4 0.1 9.6 5.2 2.8 6.3 3.5 2.5 1.4 3.5 2.4 12.1 4.1 2.5 8.0 3.0 2.8 2.8 0.0 5.9 5.7 4.9 12.6 8.1 14.0 12.8 4.2 3.2 2.6 5.9 7.4 4.3 5.0 7.3 4.8 5.0 9.1 3.2 9.3 1.8 4.9 6.2 10.9 4.1 7.6 3.5 5.2 5.3 4.4 5.1 4.8 12.6 3.6 3.7 3.5 6.1 3.2 3.9 2.6 4.5 9.6 8.5 3.7 6.0 8.2 4.8 5.7 4.8 5.0 5.0 5.2 4.4 7.3 4.0 6.9 3.4 9.6 6.9 6.7 10.0 6.8 8.5 4.2 5.8 4.0 4.0 2.8 2.4 10.7 0.0 6.1 1.9 4.0 8.9 13.7 6.6 4.7 0.1 3.0 0.3 0.2 1.8 35.0 0.5 28.1 0.6 16.9 27.9 0.5 0.6 5.2 19.2 0.6 24.4 0.7 0.3 11.0 10.4 5.9 5.0 37.3 10.1 5.2 2.7 0.1 9.6 1.4 0.0 12.6 5.9 20.5 3.2 14.6 128.9 24.4 8.2 15.5 8.5 27.3 55.7 13.9 11.2 17.9 10.0 8.3 16.5 104.3 10.5 95.5 7.3 7.9 8.0 5.4 18.2 15.7 15.0 9.1 35.4 224.3 7.3 11.8 11.3 16.8 15.8 11.4 47.9 15.0 11.0 4.0 161.5 187.5 9.9 12.2 8.6 7.6 8.8 17.4 9.0 8.8 38.4 11.8 24.9 247.2 200.6 113.6 6.3 9.6 14.3 30.1 12.7 10.6 13.6 8.8 79.8 0.0 25.5 9.0 31.4 26.4 12.8 6.7 3.7 79.4 23.3 11.5 9.5 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.4;endometrium 1: 5.5;intestine: 7.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 199.5;Inhibitory neurons: 160.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 3.6" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 5.7;cerebellum: 14.4;cerebral cortex: 6.5;hippocampal formation: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 20.0;RT4: 37.4" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" 0.0 2.2 3.7 1.0 5.7 0.0 0.0 14.4 6.5 0.3 0.0 7.4 3.2 5.5 0.0 0.0 0.1 1.0 0.0 7.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.0 5.0 2.5 0.0 1.1 0.0 0.0 7.6 2.9 1.5 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 37.4 0.1 5.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.7 14.4 6.5 7.2 0.5 0.2 0.0 0.1 1.5 0.0 1.5 1.7 0.0 0.0 3.9 0.2 0.5 0.1 0.5 0.0 16.5 0.2 0.1 3.5 0.0 3.4 0.0 0.0 0.0 0.7 43.2 0.0 2.6 1.7 2.2 1.3 4.0 0.0 0.0 199.5 0.2 0.3 0.3 10.2 14.6 0.0 0.0 0.7 0.0 0.0 16.8 160.7 1.8 0.0 0.0 0.3 0.4 0.0 0.2 0.0 3.7 0.0 0.2 1.0 2.0 4.0 2.8 23.0 0.0 0.0 0.4 17.3 0.0 0.1 0.8 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.8 0.4 0.0 0.7 0.4 PURG "PURG-A, PURG-B" ENSG00000172733 "Purine rich element binding protein G" Q9UJV8 8 30995802-31033715 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;retina: 4.1" "Cell type enhanced" "Detected in some" "Astrocytes: 61.0;Excitatory neurons: 57.2;Inhibitory neurons: 69.5;Late spermatids: 22.0;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 27.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.1;JURKAT: 4.3;NTERA-2: 4.8;SH-SY5Y: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047746 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" Nucleoli "HPA047746: AB_2680145" "unprognostic (3.37e-1)" "unprognostic (2.15e-1)" "unprognostic (6.69e-2)" "unprognostic (7.33e-3)" "unprognostic (3.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.51e-3)" "unprognostic (1.10e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "unprognostic (4.79e-2)" "unprognostic (8.72e-2)" "unprognostic (1.46e-3)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (1.83e-2)" "unprognostic (5.30e-2)" 0.3 0.4 7.7 0.2 8.3 0.0 0.2 10.5 9.0 1.3 0.5 0.3 0.1 2.0 0.6 0.2 0.4 0.8 0.4 8.7 7.7 0.4 0.0 0.2 0.2 6.6 6.7 0.5 0.0 0.0 3.0 0.2 7.4 0.5 0.1 4.1 0.3 0.6 0.1 0.0 0.2 1.3 6.1 0.6 0.2 2.6 7.3 0.1 0.2 0.2 0.1 0.2 0.8 6.5 0.0 0.0 6.1 0.1 0.0 0.0 0.0 0.1 0.3 0.5 1.2 0.0 0.0 0.1 0.0 0.0 2.1 0.0 2.0 0.0 0.7 0.0 3.1 1.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.9 0.0 0.7 3.0 4.3 0.3 0.4 0.1 0.0 0.6 0.0 4.8 0.0 0.2 1.6 0.8 0.0 0.0 0.0 0.8 5.7 0.0 0.0 0.0 2.2 0.0 0.0 1.9 2.0 2.5 0.0 0.3 0.2 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.3 10.5 9.0 8.7 7.7 6.6 6.7 7.4 6.1 7.3 6.5 0.5 0.0 0.0 61.0 0.0 0.0 0.0 0.0 0.0 13.3 0.1 0.3 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 17.3 0.2 3.2 0.5 0.0 0.0 57.2 0.0 0.0 1.1 0.0 0.1 0.0 3.6 0.0 0.0 0.0 20.2 69.5 0.0 0.0 0.0 0.3 22.0 0.6 0.1 0.0 12.2 0.0 10.8 0.0 49.3 27.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 1.3 4.2 1.5 0.0 0.0 0.0 0.1 1.8 0.0 0.0 PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridine synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: AB_2679066, HPA049582: AB_2680824" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-2)" "unprognostic (2.90e-2)" "unprognostic (8.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-4)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" "unprognostic (9.45e-2)" "unprognostic (1.15e-3)" 3.6 3.7 2.7 4.1 2.7 5.1 5.4 2.9 3.4 3.0 3.2 3.6 7.5 3.3 6.4 2.7 3.7 4.1 3.7 2.7 2.5 4.8 15.0 4.9 6.8 2.7 2.6 4.8 4.0 3.9 2.9 3.2 3.0 4.8 4.4 3.9 3.8 2.6 3.1 4.9 9.3 2.7 2.9 4.8 3.4 4.5 2.9 4.5 6.9 1.8 6.8 2.6 1.6 3.6 3.2 1.7 4.9 8.4 4.1 4.6 5.3 6.1 5.5 6.0 5.6 4.8 4.4 12.8 6.3 3.4 5.4 4.2 5.7 4.9 7.4 10.0 2.9 9.0 2.5 15.9 7.6 10.6 5.8 5.3 6.0 4.2 9.4 7.7 7.9 9.1 9.2 6.4 4.6 2.7 8.0 8.7 4.4 3.0 3.5 7.7 6.6 4.7 4.3 6.3 2.8 3.9 5.0 9.7 9.9 3.5 3.4 6.3 5.9 5.7 4.6 3.9 4.7 8.1 3.8 23.6 5.0 6.8 6.5 9.1 1.2 1.1 2.3 1.3 2.5 3.0 1.4 1.6 0.9 1.7 1.7 1.9 2.3 3.1 4.8 3.0 1.0 1.1 2.7 2.7 2.9 3.4 2.7 2.5 2.7 2.6 3.0 2.9 2.9 3.6 6.6 0.0 14.3 20.5 6.8 2.4 3.5 3.3 1.8 6.6 5.9 2.8 5.1 1.5 4.3 3.7 0.0 7.0 8.1 11.9 7.9 3.7 1.6 6.2 4.3 5.8 1.2 5.9 28.3 5.1 4.7 3.1 5.1 8.5 0.0 9.9 4.6 16.3 5.8 1.7 21.7 2.5 4.1 5.7 2.1 1.8 3.1 4.6 1.8 14.0 9.0 7.0 7.2 19.1 24.4 3.5 3.0 1.5 4.6 3.8 26.7 6.3 7.7 7.1 6.6 3.1 3.0 13.9 13.4 3.9 2.3 12.4 6.6 8.2 4.5 10.6 PVALB D22S749 ENSG00000100362 Parvalbumin P20472 22 36800684-36819479 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "parathyroid gland: 2129.3" "Group enriched" "Detected in some" 7 "Distal tubular cells: 641.8;Horizontal cells: 1527.7" "Cancer enriched" "Detected in many" 4 "renal cancer: 59.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Cell line enriched" "Detected in some" 291 "RPMI-8226: 1561.0" "Region enriched" "Detected in all" 5 "cerebellum: 2120.1" "Low region specificity" "Detected in all" "CAB002515, HPA048536" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" No NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Nucleoli, Cell Junctions" "CAB002515: AB_563948, HPA048536: AB_2680433" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "unprognostic (9.75e-2)" "unprognostic (1.79e-3)" "unprognostic (7.80e-2)" "unprognostic (2.49e-2)" "unprognostic (2.52e-2)" "unprognostic (6.53e-2)" "unprognostic (2.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-1)" "unprognostic (5.21e-2)" "unprognostic (6.92e-2)" "unprognostic (1.91e-1)" "unprognostic (1.65e-2)" "unprognostic (8.99e-3)" 0.4 1.0 82.5 0.7 40.2 0.1 15.0 255.6 86.5 0.1 8.6 0.3 0.2 1.4 0.8 0.1 0.1 0.3 0.2 9.3 100.5 82.1 5.7 2.2 2.4 127.4 85.7 0.5 0.2 2129.3 1.2 2.4 105.7 0.3 0.3 373.5 2.7 0.7 13.6 0.1 0.3 0.5 50.9 3.2 0.8 1.5 275.5 0.3 5.0 0.4 3.1 3.8 0.2 51.8 0.0 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.1 0.4 1561.0 0.0 5.3 2.3 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 4.6 0.0 0.0 0.9 0.3 15.1 82.5 40.2 255.6 86.5 9.3 100.5 127.4 85.7 105.7 50.9 275.5 51.8 0.0 0.0 0.0 3.9 0.3 0.0 0.0 0.0 0.0 51.3 2.4 2.0 0.6 0.0 0.0 38.6 10.4 0.3 0.0 0.0 641.8 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 11.4 0.2 30.0 0.2 53.8 1527.7 29.7 0.0 0.0 2.9 0.0 0.1 0.6 15.7 0.0 2.8 0.1 37.4 0.0 3.0 3.3 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 150.5 0.0 1.0 0.0 0.0 3.6 0.0 0.0 0.4 0.9 0.0 0.0 0.1 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 732.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 159.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 19.9 16.7 71.6 31.5 161.3 73.1 15.8 112.3 109.2 46.7 20.4 23.3 10.6 23.5 8.4 11.3 17.5 15.5 17.8 84.1 115.0 18.2 11.6 20.6 43.0 158.2 131.3 18.3 15.7 21.2 13.4 29.7 154.1 12.8 10.5 35.6 14.8 11.7 18.8 14.3 19.3 18.7 82.1 25.2 16.3 12.4 119.0 13.7 63.1 14.3 44.9 19.5 30.2 320.5 13.7 6.9 6.8 12.0 79.7 70.0 17.8 22.6 42.5 19.7 27.3 4.0 3.1 74.7 5.1 33.6 28.4 4.2 18.7 13.2 21.8 18.5 12.5 13.1 11.3 5.8 87.5 112.8 22.5 57.4 31.6 24.6 42.0 72.5 17.8 49.1 15.7 26.1 35.7 5.3 26.2 122.2 7.8 4.1 19.7 40.7 9.4 13.4 12.6 8.0 6.0 4.0 14.2 11.0 19.0 10.7 34.8 122.9 17.9 24.9 11.0 48.5 23.9 19.4 21.6 73.7 36.2 159.3 10.7 39.5 44.6 69.1 23.8 37.2 20.7 62.6 17.1 20.3 41.8 69.6 15.3 17.5 73.5 21.6 57.1 32.1 21.1 32.0 71.6 161.3 112.3 109.2 84.1 115.0 158.2 131.3 154.1 82.1 119.0 320.5 20.1 9.6 6.3 28.4 59.8 14.1 5.8 5.6 7.4 31.0 5.9 7.1 13.1 7.2 6.0 23.9 20.9 19.7 31.7 8.3 33.2 7.1 69.7 9.1 33.0 14.2 7.8 19.3 33.8 5.7 6.8 41.5 6.1 16.0 19.7 15.2 16.4 7.5 13.6 20.2 53.7 5.0 2.0 24.5 31.1 38.3 30.7 25.2 17.8 30.0 28.6 32.7 30.9 79.4 732.6 3.0 5.5 25.2 17.6 6.0 8.7 12.2 6.4 22.2 19.7 18.7 18.2 16.8 21.9 10.1 13.1 35.2 16.9 18.3 5.0 3.9 PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 83.1 60.9 28.7 49.1 30.8 81.4 74.4 27.6 30.5 64.5 33.7 69.0 55.7 56.3 18.7 30.9 72.3 38.2 84.2 28.0 28.5 70.2 29.5 84.6 29.3 37.1 30.8 28.5 34.5 27.8 29.5 73.3 30.3 58.9 49.9 61.8 49.4 40.6 119.2 45.6 61.1 44.5 31.8 72.5 47.5 26.5 36.6 25.9 58.1 46.1 18.4 75.8 53.2 29.2 182.4 87.5 31.3 30.1 60.4 158.1 206.1 151.8 128.6 118.9 61.5 102.5 108.9 12.2 94.6 154.9 115.1 126.0 21.7 272.0 93.0 9.9 18.6 2.3 63.8 37.9 86.8 2.7 3.6 76.5 176.2 125.3 143.9 139.7 211.6 32.2 32.4 19.5 239.3 119.6 11.1 4.1 43.5 77.1 300.8 26.2 51.0 10.8 121.4 171.9 48.7 14.5 133.2 40.3 81.7 72.1 96.1 14.8 289.9 78.9 86.7 103.6 183.9 20.4 12.3 4.6 228.9 27.0 159.2 40.8 44.2 49.2 84.5 15.7 45.3 1.7 38.4 56.0 26.2 1.1 29.5 40.3 169.6 51.8 0.8 4.1 31.4 60.6 28.7 30.8 27.6 30.5 28.0 28.5 37.1 30.8 30.3 31.8 36.6 29.2 93.6 57.7 27.9 11.8 3.0 42.3 40.6 32.8 15.4 7.8 20.3 22.9 14.7 22.8 33.3 42.3 33.3 40.8 61.6 83.1 19.6 31.6 2.1 26.0 16.7 71.0 54.6 6.1 5.1 40.2 152.4 29.7 37.2 28.8 18.3 6.2 62.2 17.2 34.2 11.8 7.7 52.7 24.4 42.3 23.7 2.8 24.2 23.5 26.6 19.7 36.8 9.1 99.9 13.0 9.2 84.8 51.6 18.8 14.5 41.7 56.6 14.6 40.0 33.6 6.6 16.7 12.1 3.5 9.1 8.1 19.5 25.0 34.4 11.3 35.8 42.6 PYCARD "ASC, CARD5, TMS-1" ENSG00000103490 "PYD and CARD domain containing" Q9ULZ3 16 31201486-31203450 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.7;skin 1: 90.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 425.8;Kupffer cells: 555.8;Macrophages: 344.2;Paneth cells: 360.0;Proximal enterocytes: 504.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 585.7;classical monocyte: 1098.3;eosinophil: 948.1;intermediate monocyte: 1138.3;myeloid DC: 829.2;neutrophil: 1638.4;non-classical monocyte: 1152.8;plasmacytoid DC: 769.2" "Group enriched" "Detected in all" 6 "dendritic cells: 829.2;granulocytes: 1638.4;monocytes: 1152.8" "Cell line enhanced" "Detected in many" "MCF7: 148.9;NB-4: 237.0;THP-1: 186.9;U-937: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006853, CAB015948, HPA049074, HPA054496" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA 640000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Cytosol" "CAB006853: , CAB015948: , HPA049074: AB_2680621, HPA054496: AB_2682506" "unprognostic (1.00e-3)" "unprognostic (2.62e-2)" "unprognostic (2.40e-1)" "unprognostic (4.67e-3)" "unprognostic (3.34e-1)" "unprognostic (1.87e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.33e-1)" "unprognostic (6.52e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (4.45e-3)" "unprognostic (2.51e-1)" "unprognostic (3.61e-2)" "unprognostic (6.97e-2)" 25.6 11.4 4.1 32.9 4.0 43.4 20.4 4.6 8.6 22.1 5.0 48.1 63.9 10.7 0.0 56.1 17.4 4.9 9.7 3.7 5.2 10.9 10.4 32.8 19.1 7.8 5.1 14.9 11.3 1.7 7.7 6.1 6.7 19.9 9.5 0.1 24.6 8.7 3.4 90.5 48.5 5.8 7.6 84.7 22.1 2.3 6.7 9.5 9.1 1.2 12.7 19.8 33.1 11.3 23.9 54.8 0.5 0.2 9.2 18.9 0.6 12.6 22.6 8.8 6.5 0.1 31.7 10.6 0.1 17.6 0.0 69.7 2.9 57.4 0.3 73.0 0.0 9.3 7.9 18.3 25.6 86.9 65.7 24.7 30.3 4.0 1.2 0.2 18.4 0.1 42.9 17.5 2.9 148.9 0.2 237.0 15.7 13.2 0.1 75.5 0.0 35.2 1.3 22.3 0.7 0.2 10.4 0.0 12.4 0.3 15.5 186.9 11.8 0.4 0.7 9.9 0.3 0.6 0.1 0.2 6.4 112.1 0.1 585.7 1098.3 948.1 178.4 1138.3 112.2 213.7 146.5 183.3 829.2 210.7 102.1 139.6 1638.4 219.2 1152.8 769.2 206.4 814.2 4.1 4.0 4.6 8.6 3.7 5.2 7.8 5.1 6.7 7.6 6.7 11.3 35.7 22.4 28.9 0.0 58.5 74.1 66.3 237.0 100.7 0.2 92.2 131.7 2.5 41.5 84.3 25.8 0.0 62.5 158.8 184.5 5.9 90.5 0.8 18.6 16.8 39.2 58.9 42.9 0.1 56.5 11.3 39.3 50.4 7.3 110.9 60.2 48.9 3.3 425.8 0.0 0.1 144.6 75.3 555.8 280.2 2.9 47.2 344.2 97.8 13.1 277.8 0.0 132.8 0.0 0.1 60.4 360.0 22.6 54.1 22.6 504.8 3.6 88.2 0.7 26.3 10.5 28.5 0.3 1.4 83.9 163.7 17.8 70.8 119.9 287.1 70.6 PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603210-143609773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Ductal cells: 10.2;Exocrine glandular cells: 9.1;Extravillous trophoblasts: 11.8;Proximal tubular cells: 12.4;Theca cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053776, HPA063416, HPA069706" Uncertain Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA053776: , HPA063416: AB_2685010, HPA069706: AB_2686178" "unprognostic (2.12e-2)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (2.44e-1)" "unprognostic (1.06e-2)" "unprognostic (2.30e-1)" "unprognostic (7.68e-3)" "unprognostic (1.79e-1)" "unprognostic (1.96e-1)" "unprognostic (2.26e-2)" "unprognostic (5.85e-2)" "unprognostic (5.44e-2)" "unprognostic (1.82e-2)" "unprognostic (3.64e-2)" "unprognostic (2.96e-1)" "unprognostic (3.54e-2)" "unprognostic (2.54e-1)" 5.0 9.7 2.8 0.4 2.9 0.6 5.2 2.7 3.3 5.1 1.0 4.2 0.5 5.2 1.1 7.1 6.0 0.8 3.9 2.9 1.6 9.7 17.2 3.8 0.9 2.3 2.2 5.1 9.2 0.6 10.0 0.4 2.7 8.7 0.6 0.7 5.8 0.5 3.0 4.0 4.1 0.4 1.5 5.9 5.5 7.0 2.7 0.4 8.4 0.3 0.7 4.4 3.8 2.1 3.2 4.0 1.6 2.5 1.8 0.6 2.0 3.0 1.4 2.9 1.9 2.9 2.6 6.2 2.1 2.0 1.1 2.6 2.0 4.0 1.1 3.0 5.3 3.7 2.2 2.0 0.6 1.9 1.0 0.8 1.9 3.1 1.9 1.2 0.7 3.7 4.3 3.1 1.9 7.2 3.0 1.7 2.1 4.5 10.4 2.8 1.8 4.3 3.4 2.2 5.3 1.4 3.6 4.9 1.6 0.8 6.4 2.0 0.9 2.9 4.0 3.4 3.1 2.5 0.8 4.2 2.6 2.0 1.9 0.2 0.9 0.0 1.1 0.6 1.2 1.3 0.8 0.8 0.6 4.7 1.1 1.0 0.1 1.3 0.7 3.0 0.9 0.6 2.8 2.9 2.7 3.3 2.9 1.6 2.3 2.2 2.7 1.5 2.7 2.1 2.9 3.2 3.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 8.8 7.7 0.0 0.0 0.6 14.7 0.0 5.1 1.6 0.0 3.9 10.2 0.0 6.8 6.6 1.9 0.0 0.0 0.0 9.1 11.8 2.9 0.0 5.2 0.0 5.5 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.8 0.0 0.0 12.4 4.4 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 2.5 1.2 14.7 0.0 0.0 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 QRICH2 DKFZP434P0316 ENSG00000129646 "Glutamine rich 2" Q9H0J4 17 76274049-76307998 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.3" "Cell type enhanced" "Detected in many" "Early spermatids: 33.8;Excitatory neurons: 9.8;Inhibitory neurons: 14.5;Late spermatids: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA052219 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA052219: AB_2681766" "unprognostic (3.11e-2)" "unprognostic (2.44e-3)" "unprognostic (9.11e-3)" "unprognostic (4.42e-3)" "unprognostic (1.35e-1)" "unprognostic (1.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.89e-1)" "unprognostic (1.83e-1)" "unprognostic (2.61e-1)" "unprognostic (8.82e-4)" "unprognostic (3.64e-1)" "unprognostic (1.39e-1)" "unprognostic (6.97e-2)" "unprognostic (7.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.71e-3)" 1.0 0.7 3.9 0.7 3.7 1.7 1.1 6.3 7.0 1.8 2.5 1.6 0.3 1.1 0.7 2.1 1.6 0.3 1.6 3.6 3.6 2.0 2.3 1.7 0.6 6.3 3.8 1.3 1.9 0.6 1.8 1.0 6.4 2.1 0.6 2.7 3.6 0.5 1.2 1.3 1.1 0.4 3.2 1.1 1.2 18.3 4.5 0.5 4.4 0.5 0.5 1.0 1.7 4.4 0.8 1.6 2.9 3.3 1.5 1.4 1.4 1.4 0.3 1.0 0.3 0.5 0.3 4.2 0.5 0.9 0.8 0.3 4.0 0.7 1.3 1.1 2.2 0.4 1.2 3.7 0.8 0.6 1.9 1.3 0.6 1.2 0.1 2.0 1.3 1.2 2.3 0.8 0.3 2.5 2.3 0.5 1.2 1.0 3.2 4.9 2.5 0.1 0.5 1.5 2.7 2.7 0.7 0.4 1.7 2.9 1.2 1.7 1.2 0.8 3.1 4.1 1.7 1.1 1.1 0.4 0.9 2.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.7 6.3 7.0 3.6 3.6 6.3 3.8 6.4 3.2 4.5 4.4 0.8 0.0 0.0 6.5 0.8 0.1 0.4 0.2 0.0 0.7 1.5 1.8 1.7 5.7 0.3 1.8 0.0 0.7 0.1 0.7 0.0 0.9 33.8 1.4 0.9 0.9 0.0 0.4 9.8 0.0 1.1 0.3 2.0 1.6 0.0 3.7 0.0 0.5 0.2 1.7 14.5 0.5 0.0 0.6 0.4 9.1 0.9 0.3 1.8 5.6 0.6 1.9 1.0 5.5 5.4 0.4 0.2 0.7 0.9 0.3 0.2 0.8 1.1 2.3 0.0 0.9 1.0 5.0 1.5 0.6 0.3 0.4 0.4 0.1 0.6 0.3 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.9;choroid plexus: 43.0;liver: 45.9;pancreas: 42.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.1;Enteroendocrine cells: 99.4;Excitatory neurons: 52.0;Inhibitory neurons: 28.3;Intestinal goblet cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 20.1;HeLa: 23.2;MCF7: 13.5;SCLC-21H: 27.2;SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Centrosome" "Intracellular and membrane" No No "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Vesicles, Plasma membrane" Centrosome "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" 0.3 1.1 53.5 0.1 55.8 0.2 0.9 57.7 84.9 1.7 43.0 5.7 5.6 0.2 1.8 1.6 0.6 0.8 1.8 60.7 46.2 1.4 45.9 0.3 0.3 48.0 45.4 0.2 42.7 3.4 34.0 0.0 49.1 4.9 5.1 6.8 18.4 0.8 1.1 1.5 6.4 0.1 44.0 0.7 13.7 1.0 47.6 0.3 1.7 2.1 0.8 0.8 0.7 51.9 1.7 20.1 0.1 5.1 0.3 0.1 0.1 0.9 1.6 0.7 1.3 0.6 4.0 0.3 1.4 1.3 0.6 3.2 1.1 0.4 0.1 2.2 2.1 0.8 23.2 1.8 0.8 0.0 0.6 0.8 0.2 0.2 0.3 4.6 0.4 3.2 0.4 0.0 2.3 13.5 0.1 1.0 1.2 6.5 1.8 1.7 1.6 3.5 7.7 1.4 27.2 5.4 0.6 24.9 1.0 0.3 8.2 0.3 0.9 0.0 3.5 0.4 0.4 2.9 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 53.5 55.8 57.7 84.9 60.7 46.2 48.0 45.4 49.1 44.0 47.6 51.9 0.2 0.0 1.1 6.5 1.3 1.3 1.6 1.4 8.0 36.1 1.4 1.4 1.6 1.5 3.4 0.0 4.2 0.0 0.0 2.6 0.0 0.4 0.1 1.0 0.3 0.4 99.4 0.0 52.0 1.0 0.0 0.4 12.8 0.4 0.0 0.5 1.1 8.1 0.2 1.7 28.3 41.9 4.1 0.3 0.0 0.1 0.0 0.1 3.6 8.4 0.0 10.7 0.0 20.1 3.6 0.5 1.8 0.0 3.8 1.5 10.5 0.6 2.3 9.1 0.0 0.3 0.3 0.0 2.4 1.5 0.1 0.1 0.2 0.3 3.2 2.6 RAB27B ENSG00000041353 "RAB27B, member RAS oncogene family" O00194 18 54717860-54895516 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 44.1" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Gastric mucus-secreting cells: 178.4;granulocytes: 246.6;Late spermatids: 209.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.2;NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 63.3;hTCEpi: 46.6;hTERT-HME1: 56.0;U-87 MG: 165.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017712, HPA019849" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 6500000 "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Plasma membrane" Cytosol "CAB017712: , HPA019849: AB_1856000" "unprognostic (1.59e-1)" "unprognostic (5.20e-2)" "unprognostic (9.89e-3)" "unprognostic (7.51e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (2.73e-3)" "unprognostic (6.82e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.39e-2)" "unprognostic (1.20e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (5.75e-1)" "unprognostic (1.29e-1)" 0.3 2.6 7.9 1.1 10.2 1.0 11.9 0.0 11.9 3.0 0.0 4.9 5.1 0.8 0.4 14.0 1.1 3.8 0.1 13.3 5.2 0.3 1.3 7.2 0.5 0.0 0.1 0.2 4.1 2.3 1.0 1.1 0.6 20.5 5.3 1.0 14.0 1.0 0.2 15.6 4.9 0.9 0.1 1.7 44.1 4.5 2.6 1.4 0.3 0.5 5.2 6.2 5.2 3.3 7.8 22.4 0.8 0.0 1.5 19.3 0.0 1.7 13.5 1.8 1.3 0.0 8.6 1.3 0.1 3.9 16.7 14.5 0.2 9.0 0.5 0.0 0.5 63.3 5.0 0.0 2.6 3.4 7.0 15.3 46.6 25.5 56.0 21.1 1.2 0.3 0.0 3.9 16.1 7.9 0.2 7.4 0.2 14.0 14.7 0.0 0.0 0.3 4.1 28.9 0.2 10.3 2.2 13.4 0.0 0.1 8.3 0.3 0.3 18.8 0.6 9.8 2.0 0.4 0.0 0.0 165.2 35.6 0.9 0.6 0.0 0.1 2.2 0.0 0.5 0.0 0.7 1.1 0.0 0.0 0.2 1.0 0.2 2.6 0.0 0.0 0.0 1.6 7.9 10.2 0.0 11.9 13.3 5.2 0.0 0.1 0.6 0.1 2.6 3.3 0.3 48.1 37.6 3.3 0.9 25.6 8.6 18.2 8.0 2.4 59.8 25.3 0.5 8.6 36.9 5.5 2.1 6.5 15.0 5.7 1.9 7.2 259.3 30.9 4.4 1.9 4.2 3.4 101.0 41.0 4.5 2.0 178.4 64.0 246.6 0.4 2.5 0.9 0.6 6.7 75.8 31.3 20.3 0.6 2.7 209.9 2.1 38.1 7.2 2.8 2.1 1.4 29.9 98.5 2.6 34.0 18.6 0.4 3.2 78.9 3.0 0.0 15.8 0.4 6.6 0.3 2.2 7.9 1.4 79.2 49.2 2.9 13.9 0.5 7.9 42.2 RAB3A ENSG00000105649 "RAB3A, member RAS oncogene family" P20336 19 18196784-18204042 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 290.7;retina: 77.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.4;Distal tubular cells: 39.2;Excitatory neurons: 34.0;Horizontal cells: 92.5;Inhibitory neurons: 41.0;Rod photoreceptor cells: 46.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 290.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 20.8;SCLC-21H: 37.5;SH-SY5Y: 18.0;U-2197: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, CAB009949, CAB078998" Enhanced Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Centrosome, Cytosol" "CAB009949: AB_632292, CAB078998: , HPA003160: AB_1079731" "unprognostic (1.82e-1)" "unprognostic (2.22e-1)" "unprognostic (6.80e-3)" "prognostic unfavorable (3.17e-4)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (1.36e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "unprognostic (4.46e-3)" "unprognostic (1.13e-1)" "prognostic favorable (6.14e-7)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (6.14e-2)" 2.6 15.6 41.0 1.7 56.7 0.9 2.1 6.8 290.7 3.3 0.0 6.4 3.1 2.7 1.5 2.5 5.2 2.0 25.7 53.4 32.5 5.9 3.8 2.5 1.5 26.8 4.6 25.8 2.0 12.8 38.4 1.4 23.3 3.9 1.8 77.5 4.0 3.9 9.9 4.1 3.2 2.1 0.0 2.8 4.5 2.2 29.4 1.3 2.3 8.9 0.9 2.6 3.6 90.5 1.4 1.6 3.5 4.9 5.7 1.4 2.2 3.2 1.9 2.2 2.9 1.4 0.9 5.2 3.4 2.6 2.0 4.2 16.6 2.0 1.0 1.1 5.3 2.1 6.3 6.0 1.4 3.6 6.2 4.6 2.0 1.2 0.6 4.2 0.6 6.4 1.1 1.8 2.0 5.2 8.0 1.0 2.9 4.4 20.8 5.5 0.3 4.4 2.3 0.8 37.5 18.0 1.6 6.6 3.7 1.4 1.4 0.6 0.7 1.8 1.4 26.2 1.8 3.2 7.4 1.3 4.9 2.7 1.7 0.0 1.3 1.8 1.3 0.9 1.8 1.9 1.3 1.3 2.9 0.9 1.7 1.8 2.2 0.3 1.3 2.6 0.8 1.3 41.0 56.7 6.8 290.7 53.4 32.5 26.8 4.6 23.3 0.0 29.4 90.5 2.3 0.0 0.0 8.5 4.7 3.2 2.5 3.7 8.6 102.4 4.8 4.8 1.3 2.8 2.2 16.5 8.4 1.6 7.4 1.6 39.2 2.3 2.4 1.0 1.3 2.6 9.6 0.0 34.0 0.9 5.2 3.1 2.0 1.4 0.0 1.6 2.5 1.6 5.2 92.5 41.0 2.8 4.1 2.2 15.3 0.2 4.4 4.5 10.6 13.1 2.9 15.4 1.0 7.5 10.1 1.0 2.0 5.7 1.1 1.1 5.3 8.3 1.2 46.5 0.0 1.8 8.2 0.4 3.6 6.0 4.8 1.8 5.3 4.5 4.2 2.1 RAB41 ENSG00000147127 "RAB41, member RAS oncogene family" Q5JT25 X 70282093-70285002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "retina: 65.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 533.8" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2197: 3.7;U-87 MG: 4.6" "HPA001510, HPA065289" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA001510: AB_1079733, HPA065289: " "unprognostic (1.32e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-3)" "unprognostic (4.25e-3)" "unprognostic (1.18e-1)" "unprognostic (3.46e-2)" "unprognostic (6.33e-3)" "unprognostic (1.85e-3)" "unprognostic (1.38e-1)" "unprognostic (2.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.04e-3)" "unprognostic (7.63e-2)" "unprognostic (2.39e-1)" "unprognostic (9.78e-3)" "unprognostic (8.42e-2)" "unprognostic (9.89e-2)" 0.2 0.8 0.5 0.5 0.6 0.4 0.1 0.3 0.9 0.1 0.0 0.3 0.4 0.2 0.0 0.3 0.2 0.5 0.6 0.3 0.4 0.3 0.1 0.3 0.5 0.5 0.5 0.8 0.1 0.0 0.2 0.2 0.4 0.2 0.0 65.5 1.0 0.0 0.5 1.3 0.7 0.0 0.4 0.5 0.2 4.0 1.0 0.0 0.8 0.0 0.0 0.3 0.1 0.5 0.5 0.5 1.3 0.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.6 0.5 0.6 1.1 0.0 1.1 0.6 0.0 0.0 0.0 0.8 1.3 0.1 1.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.5 1.2 0.0 0.3 0.8 0.5 0.8 1.7 1.7 0.3 0.9 0.9 0.0 0.4 0.8 1.5 0.5 0.3 1.5 0.6 0.3 1.4 1.6 0.6 0.7 3.7 0.8 0.7 1.1 0.8 4.6 1.1 1.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.3 0.9 0.3 0.4 0.5 0.5 0.4 0.4 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 533.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 28.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 1980.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 3900000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: AB_2680167" "unprognostic (8.66e-3)" "unprognostic (2.47e-1)" "unprognostic (4.00e-1)" "unprognostic (2.40e-2)" "unprognostic (1.88e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (1.74e-5)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.63e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (4.13e-2)" "unprognostic (8.72e-3)" 157.4 108.0 237.0 96.8 250.4 94.5 146.4 242.4 290.7 154.8 206.5 190.5 167.4 150.7 149.9 316.9 145.1 125.9 129.4 240.2 240.6 150.5 136.2 147.5 96.4 249.4 244.8 135.8 92.2 151.1 77.5 180.2 249.2 122.8 199.6 52.2 137.9 145.0 179.5 189.2 161.9 179.3 260.2 96.6 160.6 51.6 241.1 115.3 127.2 141.1 169.6 205.3 188.6 262.9 519.9 230.9 233.0 255.1 270.1 341.8 138.6 284.9 348.0 371.6 375.8 227.3 474.8 145.5 179.7 400.9 384.2 359.4 251.5 345.9 471.9 68.3 207.8 146.6 171.7 166.5 323.7 134.0 114.6 229.7 302.8 268.4 297.6 281.7 333.4 141.3 266.2 111.7 406.4 377.3 74.0 312.4 419.1 261.9 272.3 129.2 236.9 214.6 481.7 322.7 175.8 295.9 201.7 726.1 241.4 264.7 409.6 396.3 341.8 242.4 364.3 300.7 334.5 84.1 99.5 135.4 223.9 250.9 470.6 31.0 117.3 63.0 23.8 83.0 15.1 46.8 26.8 30.9 112.8 49.9 33.0 21.8 168.6 26.1 83.5 64.5 46.1 47.0 237.0 250.4 242.4 290.7 240.2 240.6 249.4 244.8 249.2 260.2 241.1 262.9 755.4 147.4 123.6 28.7 155.9 934.1 981.6 232.1 429.2 90.4 485.3 593.8 200.6 484.7 164.8 356.8 25.0 802.8 224.1 920.9 536.1 183.5 77.6 388.7 362.9 641.2 336.7 313.3 43.3 174.2 1064.1 415.9 305.3 422.8 130.9 325.4 580.8 367.1 832.0 146.4 35.3 632.9 179.0 811.3 1066.7 58.8 476.3 705.7 458.9 66.5 607.2 341.1 191.6 23.1 56.7 299.1 754.4 472.8 212.2 1495.5 816.4 832.0 214.1 64.2 479.9 346.6 466.6 216.6 373.1 774.5 1148.6 845.4 180.0 353.6 573.7 1980.7 RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.7;Spermatocytes: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 319.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: AB_2679250" "unprognostic (5.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.68e-5)" "unprognostic (3.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.03e-2)" "prognostic favorable (5.33e-4)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (7.62e-2)" "unprognostic (2.41e-1)" "unprognostic (9.52e-2)" "unprognostic (2.42e-2)" 10.8 20.2 15.5 10.0 15.7 23.1 15.3 19.0 18.4 10.8 13.4 12.4 7.5 12.6 22.0 13.0 11.2 11.0 25.7 16.4 15.0 12.8 13.3 8.8 22.0 14.9 13.8 12.5 10.6 20.1 10.5 15.1 16.0 17.4 14.5 13.5 10.7 12.0 18.3 10.6 8.7 13.8 13.2 12.2 11.6 20.2 14.6 21.2 12.3 17.3 19.1 10.9 8.6 18.2 63.7 72.1 43.3 48.5 22.9 19.6 100.1 34.2 14.5 43.5 55.3 31.0 39.3 37.4 48.9 23.5 58.8 23.3 59.5 46.6 81.7 91.6 123.0 53.0 84.6 119.4 23.3 69.1 45.0 12.1 42.2 47.8 38.6 24.0 50.0 60.9 83.6 48.5 37.0 319.1 96.8 95.3 12.1 42.5 66.5 62.1 69.5 69.8 26.9 39.6 54.3 49.6 27.3 12.0 53.5 11.1 39.2 71.6 16.5 37.6 100.1 34.3 42.4 44.1 187.2 111.5 38.3 67.1 42.0 27.6 9.2 12.5 15.6 14.3 15.2 18.0 16.9 17.2 15.9 17.3 18.2 17.4 5.1 15.0 12.5 14.3 27.1 11.0 15.5 15.7 19.0 18.4 16.4 15.0 14.9 13.8 16.0 13.2 14.6 18.2 20.5 19.2 13.9 10.1 20.5 11.9 18.7 42.9 15.9 15.0 25.1 34.0 63.7 7.2 20.9 16.5 6.2 67.8 15.0 7.1 58.7 25.7 117.7 17.3 13.0 19.3 6.7 43.8 21.5 18.6 94.1 19.8 7.1 13.0 22.9 23.3 15.7 15.7 33.4 16.8 17.7 11.7 32.6 16.1 47.7 65.4 17.4 21.8 24.9 13.1 18.7 31.3 21.6 23.1 22.8 13.0 10.4 15.4 28.5 17.2 5.7 24.6 14.1 26.9 32.9 14.7 23.9 140.7 98.3 15.9 10.7 36.3 20.5 28.2 15.3 13.9 RAI14 "DKFZp564G013, KIAA1334, NORPEG, RAI13" ENSG00000039560 "Retinoic acid induced 14" Q9P0K7 5 34656328-34832612 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 208.2;Early spermatids: 210.1;Late spermatids: 364.3;Syncytiotrophoblasts: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 267.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 23.8" "HPA036949, HPA036950" Supported Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Actin filaments, Cytosol" "HPA036949: AB_10670568, HPA036950: AB_10669721" "unprognostic (7.63e-2)" "unprognostic (9.86e-2)" "unprognostic (4.87e-2)" "unprognostic (1.40e-1)" "unprognostic (3.38e-2)" "unprognostic (4.75e-2)" "unprognostic (5.49e-2)" "unprognostic (6.18e-2)" "unprognostic (6.28e-2)" "unprognostic (2.62e-1)" "unprognostic (8.18e-2)" "unprognostic (4.58e-2)" "prognostic unfavorable (9.75e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.33e-1)" "unprognostic (4.81e-2)" "unprognostic (4.34e-2)" 10.6 9.0 10.1 21.6 14.5 2.4 9.8 13.3 9.8 51.2 17.5 22.1 7.0 53.6 6.2 10.0 13.8 18.7 6.8 8.0 9.4 18.9 27.5 26.2 14.7 18.1 13.9 9.5 7.9 10.8 4.9 34.6 17.1 11.4 10.3 10.2 16.5 25.4 1.9 19.5 7.5 58.0 15.6 39.4 10.8 39.2 12.7 6.3 10.1 2.3 10.2 43.0 14.3 20.0 12.5 48.5 55.2 37.1 29.0 100.9 70.3 147.0 118.3 83.3 83.0 36.7 15.6 2.9 57.0 72.5 90.5 8.2 64.0 109.0 179.2 0.2 30.5 20.6 43.3 22.9 90.0 0.5 1.9 94.8 34.0 149.4 118.1 136.7 267.4 4.6 29.4 1.0 110.1 10.0 2.3 0.7 43.3 7.8 47.0 18.2 84.1 0.6 97.4 70.1 14.4 7.9 86.8 12.8 39.5 80.5 14.9 2.3 173.2 134.1 71.7 33.5 65.1 3.1 0.1 0.4 113.5 0.4 53.5 0.9 0.2 0.1 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.0 0.0 10.1 14.5 13.3 9.8 8.0 9.4 18.1 13.9 17.1 15.6 12.7 20.0 16.2 105.8 208.2 33.3 0.9 12.0 32.2 46.7 23.9 3.2 27.8 9.9 5.2 7.2 81.8 35.0 68.8 32.3 0.6 17.9 7.9 36.1 210.1 35.7 36.1 96.1 1.8 2.7 6.6 28.5 75.3 25.0 11.2 36.1 3.8 22.7 17.2 23.0 7.2 15.2 6.0 1.1 16.2 1.6 4.3 364.3 72.1 4.6 5.4 15.0 1.0 19.3 0.0 31.2 60.1 53.3 5.1 31.6 0.1 26.6 6.3 25.3 24.8 5.1 0.0 6.0 33.4 9.0 9.2 6.4 15.8 156.1 3.4 11.4 2.6 61.5 RALBP1 "RIP, RIP1, RLIP76" ENSG00000017797 "RalA binding protein 1" Q15311 18 9475009-9538114 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transport "GTPase activation, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Collecting duct cells: 480.1;Extravillous trophoblasts: 518.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 195.6" "Lineage enriched" "Detected in all" 10 "granulocytes: 195.6" "Cell line enhanced" "Detected in all" "OE19: 239.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046010, HPA046651" Approved Approved "Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Nuclear membrane, Vesicles" "CAB046010: AB_11126824, HPA046651: AB_2679738" "unprognostic (1.23e-1)" "unprognostic (5.84e-3)" "unprognostic (1.58e-1)" "unprognostic (1.74e-2)" "unprognostic (8.24e-2)" "unprognostic (1.12e-1)" "unprognostic (5.72e-2)" "unprognostic (9.90e-2)" "unprognostic (1.53e-1)" "prognostic favorable (8.47e-4)" "unprognostic (4.03e-3)" "unprognostic (1.76e-1)" "prognostic favorable (5.39e-6)" "unprognostic (1.28e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (1.26e-1)" 29.7 20.4 42.7 23.4 44.1 30.7 27.8 45.8 82.2 26.8 38.6 34.1 18.7 22.1 23.5 50.3 24.8 20.3 28.5 40.7 45.1 42.7 19.9 22.6 24.0 44.1 48.0 26.3 15.4 47.9 16.8 31.4 44.4 32.6 25.4 13.5 25.0 48.2 38.5 75.9 20.4 21.1 43.6 26.5 25.7 13.0 45.3 29.3 22.9 32.5 25.4 33.8 33.3 45.1 58.9 37.6 34.2 39.0 38.3 60.7 43.3 67.7 38.1 35.6 38.0 42.6 57.5 70.5 47.0 64.8 50.2 32.8 48.1 52.7 44.2 71.4 38.5 38.5 34.6 32.7 31.2 114.8 43.0 42.0 52.2 49.6 48.7 47.7 60.6 64.6 53.7 67.7 56.2 46.3 70.7 50.9 25.4 239.5 31.9 93.6 59.4 54.2 48.4 80.7 44.7 34.8 58.2 52.8 30.9 52.3 32.9 53.8 67.4 105.0 76.9 72.3 81.9 38.7 42.9 77.9 45.6 53.4 40.5 13.0 9.6 15.7 10.3 10.6 8.7 9.9 8.7 8.8 8.7 7.5 7.3 9.4 195.6 14.8 17.8 19.8 6.4 4.5 42.7 44.1 45.8 82.2 40.7 45.1 44.1 48.0 44.4 43.6 45.3 45.1 101.8 57.7 35.7 15.3 48.0 156.4 80.9 59.9 112.7 42.6 96.0 102.2 64.8 88.6 64.6 480.1 29.2 104.2 70.9 122.6 123.3 119.4 16.1 99.1 82.6 86.9 74.2 175.7 25.4 90.7 518.6 71.6 56.1 179.4 40.5 85.8 78.9 88.3 70.1 52.2 26.7 87.7 109.9 92.8 69.7 9.5 72.7 78.4 58.7 20.6 99.6 47.6 83.4 17.1 25.3 166.3 78.2 87.3 63.2 174.4 61.0 115.0 38.6 37.3 65.7 76.8 105.6 66.7 80.0 149.6 242.5 44.6 62.6 128.4 90.1 216.4 RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3" "Cell type enhanced" "Detected in many" "Early spermatids: 112.7;Excitatory neurons: 100.6;Glandular and luminal cells: 59.5;Inhibitory neurons: 152.9;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 4.0;SK-BR-3: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: AB_10599825, HPA029569: AB_10601571" "unprognostic (4.63e-2)" "unprognostic (2.63e-3)" "unprognostic (1.06e-1)" "unprognostic (8.28e-2)" "unprognostic (1.75e-3)" "unprognostic (5.12e-3)" "unprognostic (1.50e-1)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (1.64e-2)" "unprognostic (2.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.35e-1)" "unprognostic (2.56e-3)" 0.2 0.8 0.3 0.1 0.2 0.1 0.2 2.3 0.6 0.2 0.8 0.2 0.2 0.5 0.2 0.0 0.4 0.5 0.2 0.1 1.1 0.4 0.3 0.8 0.3 0.9 0.9 0.2 1.4 0.8 0.4 0.8 1.3 0.4 0.4 0.8 0.8 0.5 0.0 0.1 0.3 0.3 0.6 0.0 0.3 1.4 0.6 0.2 1.0 0.0 0.1 0.1 0.1 1.1 0.0 0.7 4.0 3.3 1.3 0.3 2.4 2.6 1.2 1.8 1.1 1.5 0.0 0.1 2.0 2.5 0.0 0.0 0.0 1.2 3.5 0.0 2.4 0.7 1.4 0.0 1.1 0.0 0.0 2.6 0.2 0.2 0.0 0.2 1.7 0.0 0.3 0.0 1.0 1.7 0.0 0.0 0.3 0.6 0.2 0.0 2.4 0.0 0.6 1.0 0.2 1.4 0.0 3.9 1.5 1.7 0.7 1.2 2.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.3 0.6 0.1 1.1 0.9 0.9 1.3 0.6 0.6 1.1 9.4 9.6 2.0 12.7 0.0 0.3 6.2 5.8 1.8 24.8 6.1 2.8 1.3 7.2 4.8 0.0 14.6 10.4 1.7 2.3 0.0 7.3 112.7 22.4 17.5 7.9 5.4 5.5 100.6 1.4 3.2 4.9 5.1 59.5 0.0 15.6 4.2 1.6 1.9 0.0 152.9 3.7 2.0 0.6 1.4 46.5 2.8 1.0 1.8 9.4 1.2 5.5 5.2 65.4 87.1 5.3 2.9 3.0 0.8 13.0 3.9 0.9 2.4 26.9 0.0 3.0 5.1 27.2 26.7 1.4 0.0 2.5 0.8 7.5 6.3 7.6 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.3 24.3 8.6 16.3 11.6 42.1 19.7 14.4 17.1 18.1 20.3 15.6 13.4 17.7 20.5 14.3 14.6 13.7 14.9 11.8 9.4 18.1 17.4 14.0 18.6 9.2 8.1 24.4 20.2 30.1 21.5 16.5 9.5 20.9 15.2 26.5 16.4 17.2 30.3 17.2 13.4 15.2 8.6 15.0 17.6 21.3 8.2 23.3 28.4 23.6 18.0 16.9 12.1 12.2 40.5 24.2 34.1 31.0 38.7 34.5 32.9 35.5 28.0 28.7 25.1 60.7 18.9 63.2 26.8 37.2 35.3 33.1 58.9 36.9 41.5 38.9 28.5 65.9 30.3 43.2 22.5 77.9 21.3 29.1 27.5 44.9 34.7 28.3 44.5 27.1 71.9 34.0 38.4 22.3 34.8 31.6 43.0 20.3 28.7 32.3 52.3 30.7 25.3 49.6 49.4 22.6 31.5 26.7 34.7 20.4 17.2 35.4 53.5 29.8 39.6 21.2 40.2 27.9 44.4 55.8 23.1 34.4 23.5 5.4 2.6 2.7 3.7 1.7 4.1 2.7 3.0 3.4 2.2 2.7 2.9 3.3 3.9 2.2 3.6 2.6 2.7 1.4 8.6 11.6 14.4 17.1 11.8 9.4 9.2 8.1 9.5 8.6 8.2 12.2 54.5 76.9 85.3 48.6 91.5 55.7 34.5 39.1 61.5 51.2 34.1 25.8 103.9 38.6 63.0 58.8 73.0 28.8 96.1 28.9 1.9 34.7 77.3 83.6 65.3 55.7 106.4 50.5 125.5 50.9 17.5 56.5 68.3 142.1 84.9 52.2 31.4 56.6 47.9 32.0 92.2 59.5 44.7 44.9 80.7 32.9 38.5 114.0 48.0 55.3 57.0 20.0 34.0 44.2 80.0 41.5 29.9 56.1 118.4 44.1 28.8 15.6 67.0 40.5 46.0 56.9 59.0 78.3 65.4 53.3 67.8 40.6 104.8 25.3 38.3 38.7 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 RAPSN "CMS1D, CMS1E, RNF205" ENSG00000165917 "Receptor associated protein of the synapse" Q13702 11 47437764-47449143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 88.9;tongue: 33.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 63.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 238.7" "Low region specificity" "Detected in some" HPA039475 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Centrosome, Cytosol" "HPA039475: AB_10794196" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (7.34e-2)" "unprognostic (4.58e-2)" "unprognostic (2.95e-2)" "unprognostic (1.44e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-3)" "unprognostic (1.35e-1)" "unprognostic (5.38e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.64e-4)" "unprognostic (3.83e-1)" "unprognostic (4.73e-3)" "unprognostic (4.48e-2)" 0.3 1.5 0.5 0.2 0.5 0.3 0.2 0.3 1.2 0.2 0.9 0.8 0.1 0.0 0.1 1.2 0.1 0.1 2.6 0.5 0.5 0.3 0.5 0.4 0.2 0.3 0.5 0.0 0.2 0.0 0.1 2.1 0.5 0.7 0.0 0.1 1.3 0.0 88.9 0.5 0.5 0.1 0.4 0.6 0.2 0.3 0.6 0.1 0.2 33.1 0.1 0.1 0.1 0.5 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.7 0.1 0.2 1.2 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 238.7 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.1 0.3 0.3 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.5 0.5 0.3 0.5 0.5 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.3 1.4 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.5 2.7 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.3 13.8 0.0 0.5 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 63.8 0.5 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.2 0.1 RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 221.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" 47.6 21.1 3.2 28.3 4.4 59.6 37.2 7.2 16.5 43.7 5.1 31.0 28.4 32.2 10.7 14.9 40.7 41.3 40.8 7.0 5.7 24.1 42.3 58.4 16.4 5.3 2.7 40.8 14.7 11.3 30.6 25.7 2.8 29.8 13.2 18.3 20.6 21.3 62.6 24.8 32.2 28.6 1.8 41.7 22.9 28.8 4.9 10.0 26.9 17.4 11.8 30.3 30.2 4.3 18.0 41.9 11.8 20.5 23.4 35.9 12.5 14.9 21.8 21.5 13.6 28.6 15.1 9.6 22.7 33.2 18.9 51.1 14.2 33.9 12.0 77.5 21.4 26.6 21.2 29.8 37.0 9.4 81.3 48.2 10.0 22.7 29.2 75.8 30.9 8.4 17.6 20.2 23.7 221.5 6.4 34.2 10.7 16.2 13.3 12.9 71.3 37.0 12.2 14.4 5.4 40.5 31.0 124.8 42.1 11.7 119.1 36.6 35.8 25.3 45.3 44.2 15.4 48.7 16.9 8.3 38.4 18.7 77.1 26.3 8.9 34.6 3.2 14.6 5.1 2.0 3.6 3.8 12.4 1.7 1.5 2.8 52.6 5.9 19.5 3.8 3.1 5.0 3.2 4.4 7.2 16.5 7.0 5.7 5.3 2.7 2.8 1.8 4.9 4.3 35.6 3.2 7.0 2.3 43.4 19.5 25.6 8.4 18.8 23.2 35.4 17.5 3.8 10.0 5.5 7.3 6.2 2.2 36.9 41.2 13.7 16.7 60.5 20.7 22.0 28.4 9.6 5.7 5.4 19.2 5.8 28.5 10.7 18.4 35.5 13.9 26.0 28.8 12.3 3.3 2.6 13.1 6.1 45.4 65.5 66.2 41.7 56.9 28.4 2.8 26.1 11.8 6.2 4.0 0.3 22.0 33.1 23.0 21.0 13.4 70.9 17.7 4.9 10.2 32.9 42.1 26.7 3.6 7.6 7.1 18.9 5.2 31.7 6.5 16.5 19.3 RARS1 "DALRD1, RARS" ENSG00000113643 "Arginyl-tRNA synthetase 1" P54136 5 168486451-168519301 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 50.8;Cytotrophoblasts: 104.2;Extravillous trophoblasts: 96.8;Hofbauer cells: 57.2;Syncytiotrophoblasts: 84.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003979, HPA004130" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 74000 "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA003979: AB_1856083, HPA004130: AB_1856084" "unprognostic (1.06e-2)" "unprognostic (1.92e-2)" "unprognostic (2.74e-3)" "unprognostic (2.82e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.59e-5)" "prognostic unfavorable (1.10e-8)" "unprognostic (3.26e-3)" "unprognostic (5.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.92e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.43e-2)" "unprognostic (2.35e-1)" "unprognostic (2.39e-1)" "unprognostic (1.33e-2)" 27.5 25.6 12.7 31.5 12.3 12.8 36.3 19.6 15.6 22.9 9.4 37.6 54.8 26.7 33.5 38.2 25.8 23.4 29.5 12.8 11.2 33.2 43.5 22.0 31.0 9.0 10.7 23.0 34.4 32.7 16.6 36.5 9.8 27.9 43.0 17.2 32.9 23.5 31.1 41.8 48.7 32.8 5.4 21.8 32.8 23.2 12.1 23.5 30.2 34.6 40.6 41.1 25.2 21.4 100.2 115.6 82.5 94.2 113.4 128.9 143.9 143.4 122.3 145.7 168.7 198.4 105.6 104.3 114.2 137.2 149.3 93.9 111.0 192.7 188.5 110.1 76.5 71.2 103.1 126.5 96.8 169.2 72.6 99.7 100.8 159.0 76.0 89.3 118.5 56.4 107.7 51.9 158.1 92.4 70.7 68.7 138.1 86.7 77.8 30.3 122.0 99.7 129.7 110.8 79.6 97.7 109.1 124.7 152.7 101.1 113.4 69.9 118.7 104.7 96.3 81.9 169.4 51.8 100.3 105.7 114.3 118.0 101.9 5.2 21.5 8.2 17.4 27.3 20.2 15.5 17.2 18.8 32.1 9.5 21.2 22.6 5.8 26.6 26.7 14.7 19.3 18.2 12.7 12.3 19.6 15.6 12.8 11.2 9.0 10.7 9.8 5.4 12.1 21.4 10.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.8 0.0 0.0 0.0 0.0 104.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 96.8 12.8 0.0 0.0 0.0 0.0 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 84.3 1.4 0.0 0.0 0.0 RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 59.8;salivary gland: 28.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 36.8;Excitatory neurons: 14.0;Gastric mucus-secreting cells: 57.1;Oligodendrocytes: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 15.3;EFO-21: 19.3;REH: 22.3;RPMI-8226: 50.0;RPTEC TERT1: 19.0;U-698: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: AB_2677598" "unprognostic (9.95e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (3.26e-5)" "unprognostic (1.27e-2)" "unprognostic (7.73e-3)" "unprognostic (1.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-1)" "unprognostic (3.02e-3)" "unprognostic (3.16e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-2)" "unprognostic (2.85e-3)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.64e-1)" 0.0 15.4 10.9 1.2 13.8 0.5 1.0 0.5 19.1 3.5 1.1 1.7 0.4 0.1 0.1 22.6 1.6 0.3 0.0 23.6 4.0 17.2 0.1 0.2 1.1 1.7 4.3 0.0 1.1 59.8 5.0 0.2 1.8 0.2 1.1 0.5 28.5 3.9 0.0 11.4 0.5 0.0 0.6 0.2 10.6 0.7 7.7 0.2 10.1 0.0 2.7 0.2 5.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 3.9 15.3 19.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 4.3 0.0 0.0 0.6 5.5 0.0 22.3 0.0 50.0 19.0 0.0 0.5 0.0 0.0 7.2 0.0 0.1 2.9 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 13.8 0.5 19.1 23.6 4.0 1.7 4.3 1.8 0.6 7.7 12.1 0.0 0.0 0.0 1.3 0.8 0.5 0.0 0.4 0.0 0.5 2.4 2.0 4.3 2.8 1.0 36.8 0.0 1.1 0.0 1.9 0.0 1.4 0.1 1.8 0.6 0.3 1.2 0.0 14.0 0.0 0.2 0.3 57.1 4.6 2.5 0.0 0.0 0.0 0.4 0.0 1.0 4.8 0.0 0.0 5.5 0.2 0.0 1.2 1.8 0.0 1.0 2.7 0.0 0.0 46.5 5.2 3.3 0.0 0.6 0.0 0.1 5.2 0.5 0.0 0.0 0.0 0.2 0.1 0.7 4.6 1.1 1.2 0.4 0.1 3.3 0.6 RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 18.1;granulocytes: 26.6;Hofbauer cells: 15.1;Kupffer cells: 32.9;Langerhans cells: 11.6;Macrophages: 19.1;monocytes: 25.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 25.7;HMC-1: 24.0;U-937: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" 3.2 0.8 0.3 6.7 0.3 20.8 0.7 0.3 0.9 1.1 0.4 1.2 1.2 0.5 0.1 1.0 1.0 1.9 0.6 0.2 0.3 0.3 0.7 3.3 1.1 0.9 0.4 0.4 1.1 0.3 0.2 2.3 0.6 0.5 0.8 0.0 0.4 0.5 0.8 0.5 1.8 2.0 0.7 8.9 0.9 0.2 1.1 1.1 0.2 1.4 0.7 2.5 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.7 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 12.5 13.5 20.1 0.0 15.4 0.0 0.1 0.3 0.0 9.4 0.1 0.0 0.0 39.4 0.0 17.9 0.7 1.4 4.4 0.3 0.3 0.3 0.9 0.2 0.3 0.9 0.4 0.6 0.7 1.1 1.0 0.2 0.0 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.3 18.1 0.0 1.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.7 0.0 0.2 0.4 0.0 0.0 26.6 0.0 1.4 0.0 15.1 0.0 0.4 0.0 0.0 32.9 11.6 0.0 0.0 19.1 1.8 0.0 25.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.3 1.5 0.0 0.0 0.1 RASSF2 "CENP-34, KIAA0168" ENSG00000101265 "Ras association domain family member 2" P50749 20 4780023-4823608 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 217.0;retina: 162.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 87.1;Langerhans cells: 75.8;monocytes: 148.5;Oligodendrocytes: 106.7;Peritubular cells: 149.7;Rod photoreceptor cells: 160.3" "Cancer enriched" "Detected in all" 5 "glioma: 48.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 56.8;BEWO: 59.2;Daudi: 62.7;HL-60: 74.7;NB-4: 96.3;U-937: 116.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051200 Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Plasma membrane, Cytosol" "HPA051200: AB_2681386" "unprognostic (6.51e-2)" "unprognostic (3.67e-3)" "unprognostic (5.31e-2)" "unprognostic (1.47e-2)" "unprognostic (3.15e-1)" "unprognostic (1.46e-3)" "unprognostic (2.80e-1)" "unprognostic (7.01e-2)" "unprognostic (1.38e-2)" "unprognostic (2.41e-2)" "unprognostic (4.93e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (3.51e-2)" "unprognostic (1.35e-1)" "unprognostic (3.49e-1)" "unprognostic (6.46e-2)" 16.4 9.7 76.1 47.1 135.2 91.2 6.9 155.5 113.5 27.9 40.0 8.4 5.3 25.4 22.5 10.0 22.1 15.6 4.2 68.9 94.7 4.0 5.9 25.4 58.6 217.0 148.8 7.0 3.1 1.5 5.0 9.1 186.4 7.3 9.6 162.8 3.0 9.3 1.2 4.2 14.5 38.7 135.8 32.7 7.0 20.6 120.0 19.5 4.7 5.0 73.6 20.7 4.9 197.0 0.1 14.5 34.9 56.8 0.4 0.0 59.2 3.5 10.0 0.6 0.2 3.4 0.1 62.7 5.6 3.1 1.4 0.2 5.1 0.0 0.8 22.7 2.1 41.1 0.0 0.7 0.0 74.7 40.1 0.1 0.0 1.3 0.0 1.3 23.4 7.0 0.2 24.0 0.0 0.1 11.0 96.3 7.8 0.0 1.1 17.1 3.9 23.8 0.0 29.0 0.4 2.8 0.0 1.0 1.7 7.4 0.0 47.0 0.7 1.5 7.4 0.7 4.6 0.3 5.9 37.8 0.3 116.8 0.4 85.6 61.5 101.3 7.7 50.1 14.6 24.3 12.0 10.4 46.8 16.4 7.8 6.5 139.5 8.5 59.9 30.7 11.8 42.1 76.1 135.2 155.5 113.5 68.9 94.7 217.0 148.8 186.4 135.8 120.0 197.0 5.5 0.0 8.7 7.5 49.3 4.7 0.0 0.1 0.0 39.2 4.1 1.7 1.9 1.5 1.9 0.0 27.1 3.0 43.0 0.1 1.9 1.2 6.0 3.2 19.6 18.6 0.0 6.1 1.5 0.9 5.1 10.9 1.1 1.0 54.3 4.5 11.4 1.2 27.1 6.7 1.3 0.7 0.0 87.1 75.8 25.1 33.2 64.6 8.8 26.2 148.5 19.3 7.2 33.7 106.7 0.6 0.0 149.7 14.3 1.2 0.0 0.3 0.1 160.3 0.0 9.4 3.5 0.7 1.0 0.3 2.6 1.4 20.8 0.8 0.0 2.3 RAX2 "ARMD6, CORD11, MGC15631, RAXL1" ENSG00000173976 "Retina and anterior neural fold homeobox 2" Q96IS3 19 3769089-3772228 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Age-related macular degeneration, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "retina: 64.5" "Group enriched" "Detected in some" 9 "Cone photoreceptor cells: 123.0;Rod photoreceptor cells: 217.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA052533 Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA052533: AB_2681862" "unprognostic (5.53e-2)" "unprognostic (1.39e-2)" "unprognostic (4.48e-1)" 0.0 0.0 0.2 0.1 0.4 0.4 0.0 0.6 0.6 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.3 1.6 0.0 0.4 0.0 0.0 64.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.6 0.4 0.3 0.3 0.3 0.4 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 14.3 0.0 0.1 0.6 0.0 0.0 0.0 123.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 217.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 RBFOX1 "A2BP1, FOX-1, HRNBP1" ENSG00000078328 "RNA binding fox-1 homolog 1" Q9NWB1 16 5239802-7713340 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 73.9;heart muscle: 25.2;skeletal muscle: 95.3;tongue: 45.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 5800.8;Inhibitory neurons: 5921.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Group enriched" "Detected in many" 10 "basal ganglia: 28.1;cerebral cortex: 73.9;hippocampal formation: 26.6;white matter: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "RH-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040809, HPA066746, HPA075862" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA040809: AB_10796228, HPA066746: , HPA075862: " "unprognostic (3.75e-3)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (5.19e-3)" "unprognostic (8.82e-5)" "unprognostic (5.02e-1)" "unprognostic (3.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-2)" "unprognostic (3.24e-2)" "unprognostic (2.23e-1)" "unprognostic (5.00e-2)" "unprognostic (2.28e-1)" 0.3 1.5 3.7 0.4 28.1 0.5 0.1 2.5 73.9 0.6 0.0 0.8 0.2 0.2 3.1 1.1 1.1 0.1 25.2 26.6 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.0 1.1 0.1 0.0 1.7 0.5 5.7 2.2 4.1 95.3 0.3 0.2 0.0 2.7 0.0 0.2 1.1 2.2 0.2 0.1 45.3 0.0 0.4 0.4 22.6 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 25.9 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.0 0.7 0.1 0.4 0.2 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.3 0.2 0.7 0.2 0.1 0.1 0.2 0.0 3.7 28.1 2.5 73.9 26.6 0.0 0.0 0.0 0.0 2.7 2.2 22.6 0.0 0.0 0.5 97.9 0.0 0.0 0.0 0.0 0.0 10.9 0.4 0.0 98.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 6.6 0.3 1.8 0.9 0.0 0.0 5800.8 0.2 0.0 3.5 0.0 0.1 0.0 47.8 0.0 0.0 0.1 0.0 5921.8 0.5 0.0 0.0 0.3 4.9 1.2 0.5 1.8 132.1 0.6 6.6 0.0 597.6 689.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.7 2.8 0.0 17.0 1.2 0.6 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 RBIS C8orf59 ENSG00000176731 "Ribosomal biogenesis factor" Q8N0T1 8 85214048-85220421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 56.0;Cytotrophoblasts: 105.8;dendritic cells: 39.1;Extravillous trophoblasts: 123.8;Hofbauer cells: 102.1;Syncytiotrophoblasts: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044805, HPA071903" Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 50: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli" Cytosol "HPA044805: AB_2679095, HPA071903: AB_2686469" "unprognostic (1.61e-2)" "unprognostic (2.98e-1)" "unprognostic (4.51e-1)" "unprognostic (1.63e-3)" "unprognostic (2.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-3)" "unprognostic (1.63e-1)" "unprognostic (1.69e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (2.29e-1)" "unprognostic (3.84e-3)" 74.4 69.3 55.7 51.0 56.1 83.2 95.2 57.4 72.4 85.3 57.0 81.0 60.6 67.0 91.1 90.2 72.2 42.8 101.1 54.6 58.2 88.5 86.2 52.3 70.8 56.9 55.6 82.7 103.1 60.6 68.9 45.6 57.5 71.6 56.8 45.8 75.2 41.4 78.0 63.9 66.3 48.8 58.5 75.4 99.0 41.5 56.1 75.1 61.3 68.6 71.3 73.9 73.5 59.8 166.6 83.1 122.6 79.4 73.4 140.2 94.8 107.6 102.7 123.1 120.5 97.2 140.0 42.1 86.8 71.8 116.2 112.9 84.8 118.2 138.1 116.6 92.5 242.1 74.2 145.8 87.0 92.5 105.7 120.0 137.0 79.4 99.7 133.3 106.4 145.3 111.9 97.8 103.7 131.0 205.8 173.1 36.1 372.8 143.3 86.9 100.6 188.2 121.2 104.7 40.7 87.1 81.7 132.8 161.0 145.5 154.4 135.9 81.8 78.1 164.9 87.5 104.2 114.1 144.8 197.4 155.8 116.8 88.9 76.6 55.2 39.2 63.5 71.7 76.7 89.3 83.7 78.9 96.9 77.7 95.8 95.0 14.1 104.7 64.4 118.7 90.8 71.0 55.7 56.1 57.4 72.4 54.6 58.2 56.9 55.6 57.5 58.5 56.1 59.8 56.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 0.0 105.8 39.1 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 123.8 27.8 0.0 0.0 0.0 0.0 0.0 0.0 102.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 76.9 7.6 0.0 0.0 0.0 RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 468.3;Late spermatids: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: AB_785011, HPA019703: AB_1856106" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (4.00e-2)" "unprognostic (1.26e-1)" "unprognostic (6.88e-2)" "unprognostic (6.43e-2)" "unprognostic (5.03e-2)" "unprognostic (2.46e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (4.70e-1)" "unprognostic (8.12e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.57e-3)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (7.51e-2)" 32.5 25.4 11.1 32.3 13.6 19.1 31.7 12.5 10.4 33.5 14.8 26.6 23.3 32.2 20.2 25.0 31.8 27.7 25.6 8.7 10.5 39.2 59.5 38.9 49.7 12.3 12.0 37.8 39.0 62.7 17.7 19.3 13.0 42.9 29.3 23.1 34.2 39.9 32.4 26.3 26.1 30.7 11.7 41.0 32.6 48.4 11.4 66.6 40.2 37.7 51.2 30.9 28.9 16.9 25.9 18.1 20.7 20.6 61.2 57.9 9.4 17.8 26.4 23.1 7.9 10.1 30.9 39.0 28.4 32.8 22.3 29.6 17.9 30.1 36.0 12.5 22.4 15.9 14.7 22.0 27.3 23.4 49.0 35.6 34.0 15.3 22.4 43.0 36.3 39.6 12.7 23.2 26.6 7.1 48.6 22.0 7.8 30.8 15.0 33.6 41.8 46.1 25.4 25.3 16.9 14.3 42.2 17.2 19.1 16.8 22.7 30.0 28.3 27.5 14.3 24.1 13.7 35.7 22.9 42.4 34.4 28.2 19.0 53.9 22.5 56.5 53.4 16.2 60.5 22.5 59.7 62.8 21.7 22.0 85.5 75.3 41.8 74.4 28.8 13.1 48.2 76.2 11.1 13.6 12.5 10.4 8.7 10.5 12.3 12.0 13.0 11.7 11.4 16.9 37.9 41.7 101.1 51.2 49.5 23.1 30.1 15.3 40.9 27.8 27.0 15.5 13.5 45.8 32.5 27.6 20.9 6.0 77.0 26.3 17.6 13.4 468.3 38.9 25.8 31.4 19.8 26.5 55.1 10.2 13.0 35.8 24.5 45.9 55.1 27.9 40.7 46.1 11.2 35.3 54.1 30.0 34.6 43.6 23.7 209.1 42.0 35.4 10.6 58.1 44.9 38.3 79.3 63.3 85.7 10.8 19.0 42.9 48.7 31.4 29.2 25.3 38.3 22.5 39.5 36.2 26.1 161.4 61.3 33.7 27.6 4.1 118.9 25.2 21.7 35.6 RBM18 MGC2734 ENSG00000119446 "RNA binding motif protein 18" Q96H35 9 122237622-122264840 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057281, HPA077955" Uncertain Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA057281: AB_2683394, HPA077955: " "unprognostic (1.75e-2)" "unprognostic (7.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (9.39e-3)" "unprognostic (7.27e-3)" "unprognostic (2.79e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "prognostic favorable (8.00e-7)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 9.0 9.5 7.4 6.4 7.9 11.7 16.4 8.0 10.1 8.9 7.3 7.5 7.0 8.8 10.3 7.7 7.4 7.6 13.5 7.8 8.8 11.4 8.4 7.2 8.1 8.2 7.9 9.5 6.9 11.9 5.7 10.4 8.6 11.1 8.1 11.5 7.9 8.3 20.7 6.8 6.1 8.7 8.0 8.0 8.5 3.6 8.0 9.5 10.0 23.1 7.6 8.7 5.4 8.4 8.1 8.3 11.2 12.4 16.1 19.8 9.7 18.0 14.7 12.1 11.2 9.6 7.8 14.1 7.7 11.8 13.3 18.5 17.6 18.7 15.1 14.5 8.0 10.5 12.6 8.2 18.1 21.1 14.0 17.0 20.8 12.7 25.8 12.1 17.6 11.3 14.6 10.7 18.3 8.8 11.1 13.0 8.7 27.2 13.7 9.7 23.2 19.3 16.9 9.0 23.3 12.3 13.6 18.9 21.3 8.8 11.0 11.8 9.8 11.3 6.4 18.3 18.0 15.5 30.7 11.7 18.6 12.9 13.8 4.5 6.2 11.4 6.3 7.2 6.1 5.8 5.5 6.2 6.5 4.0 5.7 6.0 6.5 5.4 9.7 4.6 6.4 5.8 7.4 7.9 8.0 10.1 7.8 8.8 8.2 7.9 8.6 8.0 8.0 8.4 19.7 32.1 12.8 2.0 18.3 21.7 11.7 28.5 19.9 12.4 27.2 20.7 51.6 10.0 23.1 25.8 2.1 32.8 23.3 17.2 27.4 23.2 75.0 14.7 19.9 21.6 19.7 28.4 9.1 16.2 44.7 15.9 13.3 16.4 17.7 14.1 13.6 13.7 27.7 3.3 12.9 16.5 34.6 21.0 17.2 76.9 13.4 18.4 19.6 4.7 20.6 16.9 27.8 6.0 10.7 23.0 18.7 17.0 16.4 20.8 14.8 26.6 19.8 14.7 19.7 15.2 25.4 19.7 22.1 16.5 25.9 56.9 23.5 16.7 14.2 20.7 RBM20 ENSG00000203867 "RNA binding motif protein 20" Q5T481 10 110644336-110839468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.8;pancreas: 20.2" "Cell type enriched" "Detected in many" 8 "Cardiomyocytes: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 6.0;HEL: 5.2;K-562: 5.0;RH-30: 16.2;SH-SY5Y: 15.0;SuSa: 4.9;T-47d: 9.2" "Low region specificity" "Detected in single" "HPA035806, HPA070358" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytokinetic bridge" Yes No "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus" "Nucleoli, Cytokinetic bridge" "HPA035806: AB_10672097, HPA070358: " "unprognostic (2.43e-1)" "unprognostic (8.24e-3)" "unprognostic (5.81e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (2.75e-2)" "unprognostic (5.47e-3)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (4.14e-3)" "unprognostic (1.44e-1)" "unprognostic (2.39e-3)" "unprognostic (3.34e-1)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (6.46e-2)" 1.5 0.1 0.8 0.2 2.6 0.1 2.5 0.4 0.8 1.5 1.8 4.1 0.1 2.9 0.6 5.6 2.6 0.4 40.8 0.8 0.4 0.7 0.1 0.9 0.1 0.8 0.9 2.7 20.2 1.2 1.7 1.6 0.6 1.3 0.4 1.2 7.3 0.7 15.6 1.2 0.8 2.2 0.5 0.1 1.0 0.8 0.8 0.5 1.0 3.8 0.6 1.0 5.5 0.7 0.0 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 2.5 6.0 5.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.4 0.0 16.2 0.0 0.0 0.0 0.1 15.0 0.1 0.0 0.6 4.9 9.2 0.0 0.0 0.3 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.6 0.4 0.8 0.8 0.4 0.8 0.9 0.6 0.5 0.8 0.7 0.3 0.0 0.0 0.7 0.2 0.1 0.2 0.4 1.2 1.4 0.8 0.5 151.5 0.0 0.1 0.0 2.1 1.6 0.0 0.7 1.9 0.0 0.8 0.5 1.2 1.5 0.0 0.0 14.8 0.2 0.2 3.3 0.0 0.1 0.0 14.6 1.4 0.0 0.1 0.0 15.4 0.7 2.0 0.0 0.0 0.8 4.4 0.0 0.0 17.8 0.0 0.1 0.0 1.5 0.6 0.0 0.1 13.5 1.0 0.0 2.0 1.5 12.4 2.7 6.6 3.7 5.4 0.5 0.8 3.7 0.0 3.1 0.2 1.7 0.2 0.3 RBM34 KIAA0117 ENSG00000188739 "RNA binding motif protein 34" P42696 1 235131183-235161283 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028606 Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA028606: AB_10601494" "unprognostic (4.53e-2)" "unprognostic (3.64e-2)" "unprognostic (7.30e-2)" "unprognostic (3.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (6.57e-4)" "unprognostic (2.98e-2)" "unprognostic (5.65e-3)" "unprognostic (2.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.69e-8)" "unprognostic (8.50e-2)" "unprognostic (1.85e-1)" "unprognostic (8.73e-2)" "unprognostic (7.09e-4)" 12.2 10.3 11.7 15.0 12.5 35.5 17.0 12.1 13.7 10.0 12.3 12.4 17.9 11.5 15.6 13.9 10.9 12.2 15.5 11.8 12.6 17.1 14.8 11.9 23.2 13.3 12.5 12.8 13.1 9.2 8.7 13.2 13.1 12.0 14.1 6.3 19.9 7.4 19.7 18.2 15.8 11.6 13.1 12.7 14.3 21.3 12.5 16.3 15.6 12.3 20.6 15.7 9.6 13.5 28.6 20.9 23.8 28.8 17.9 33.3 52.8 29.3 24.6 29.4 30.1 26.9 33.7 49.4 29.9 21.0 22.1 40.5 29.0 28.9 28.2 44.4 47.8 35.7 17.0 20.1 35.1 60.4 34.5 28.0 33.2 26.5 19.6 26.5 26.8 50.5 54.5 23.7 38.7 18.0 49.9 48.3 65.3 43.8 15.8 48.0 23.2 57.3 29.5 22.7 26.2 47.1 39.2 27.0 66.4 17.0 55.2 63.5 21.0 26.2 23.0 36.1 59.9 27.8 47.5 47.4 30.8 38.0 40.8 113.9 36.0 44.1 46.1 42.5 55.6 74.1 53.0 59.8 37.2 54.5 49.0 57.4 18.3 58.2 46.4 59.5 77.5 51.5 11.7 12.5 12.1 13.7 11.8 12.6 13.3 12.5 13.1 13.1 12.5 13.5 4.3 19.2 12.8 12.1 11.9 3.2 10.0 7.3 10.2 2.6 6.3 3.7 3.4 7.2 9.1 3.7 10.4 6.2 19.3 4.1 5.9 6.6 7.2 3.2 5.1 6.9 7.8 3.8 10.6 6.2 4.5 10.3 4.6 6.0 23.4 8.0 6.1 3.6 3.3 0.0 11.5 2.7 8.2 5.4 3.2 7.9 4.1 7.1 3.6 15.9 9.4 4.0 23.7 10.1 11.9 8.6 9.6 5.7 10.2 5.3 5.3 12.8 10.7 5.7 0.0 5.0 4.4 7.1 5.3 8.0 3.8 6.2 16.2 3.3 4.5 7.7 RBM39 "CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2" ENSG00000131051 "RNA binding motif protein 39" Q14498 20 35701347-35742312 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001591 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Centriolar satellite" NA NA 19000 "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Microtubules, Centriolar satellite" "HPA001591: AB_1079749" "unprognostic (1.37e-2)" "unprognostic (4.97e-1)" "unprognostic (2.72e-2)" "unprognostic (9.09e-2)" "unprognostic (3.47e-1)" "unprognostic (4.99e-2)" "unprognostic (3.55e-3)" "unprognostic (4.56e-2)" "unprognostic (7.83e-2)" "unprognostic (2.65e-1)" "unprognostic (2.04e-2)" "unprognostic (7.65e-3)" "prognostic unfavorable (2.78e-5)" "unprognostic (1.88e-1)" "unprognostic (2.86e-1)" "unprognostic (2.64e-1)" "unprognostic (2.28e-3)" 70.1 55.8 18.4 37.7 17.6 172.0 44.6 33.5 28.0 57.8 22.2 56.0 35.1 54.5 9.2 62.3 61.4 40.8 57.3 16.5 25.0 52.2 47.7 62.2 42.3 24.2 24.0 71.1 41.2 27.3 50.0 40.9 19.4 50.2 16.9 49.5 53.4 22.3 70.3 51.2 46.9 19.2 16.0 56.4 49.7 34.3 16.9 51.1 54.2 33.1 24.1 50.7 62.1 26.5 98.8 87.6 77.0 78.5 48.8 53.8 78.8 131.0 50.6 59.6 60.2 109.3 78.5 137.5 90.6 38.9 67.9 91.2 122.3 67.9 66.5 94.6 96.7 174.6 80.7 101.2 23.4 158.6 99.9 14.4 97.6 68.9 38.4 63.7 57.8 46.4 195.5 117.6 46.3 72.2 194.5 87.9 103.2 87.5 96.8 104.9 136.2 91.7 41.5 56.2 77.9 63.4 91.1 94.7 78.4 109.3 70.6 94.6 91.4 100.8 92.5 90.5 115.8 71.6 164.3 204.0 64.7 123.2 79.2 250.9 120.4 197.5 104.7 111.1 103.6 131.1 91.5 97.6 111.8 140.5 85.7 82.1 427.7 127.2 102.2 160.9 114.7 95.7 18.4 17.6 33.5 28.0 16.5 25.0 24.2 24.0 19.4 16.0 16.9 26.5 302.0 233.9 280.9 144.3 441.7 616.4 521.0 283.0 284.0 258.5 339.1 295.4 189.2 191.6 267.6 200.5 316.9 375.2 624.9 278.1 189.8 203.8 48.1 359.2 496.0 299.7 295.3 214.2 130.1 186.0 389.6 337.9 254.9 540.8 525.8 304.4 215.3 202.1 199.8 220.4 120.9 331.3 215.7 207.7 469.5 41.9 262.5 335.5 270.3 129.3 274.3 208.7 400.6 136.2 160.5 221.3 254.8 214.4 391.0 453.6 271.8 150.6 248.0 386.5 164.3 504.0 410.2 263.5 228.1 215.8 586.9 561.6 490.8 218.2 282.8 532.1 RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" 19.4 7.1 12.5 5.7 11.5 3.6 17.4 9.3 13.1 14.7 15.1 12.9 4.7 13.7 9.3 8.2 13.7 9.5 15.6 9.2 10.0 14.7 3.4 37.3 3.2 14.5 11.7 12.6 7.0 8.6 6.1 23.5 13.4 11.2 8.8 6.0 10.1 8.7 8.4 8.3 9.0 12.1 9.8 10.5 8.5 4.3 15.2 3.5 18.3 10.8 3.9 10.3 13.9 11.7 28.8 24.3 10.5 14.9 23.7 22.7 9.3 34.8 37.0 26.9 23.9 18.7 50.2 0.2 42.1 36.6 11.1 20.4 7.8 57.8 30.1 8.3 6.7 3.7 19.0 4.8 15.4 3.8 6.5 20.9 13.9 28.1 33.5 31.4 51.1 6.1 1.8 6.5 47.0 3.7 4.1 4.9 6.2 0.0 7.5 2.4 11.5 0.3 34.1 6.4 0.8 6.9 39.6 14.9 5.1 22.2 16.0 6.3 78.2 16.7 35.8 9.5 8.4 6.1 2.5 1.7 6.1 0.9 23.6 0.6 4.7 1.6 0.8 1.3 0.9 0.3 0.3 1.2 2.7 0.5 0.9 0.6 1.6 1.0 0.3 0.6 0.5 0.8 12.5 11.5 9.3 13.1 9.2 10.0 14.5 11.7 13.4 9.8 15.2 11.7 74.4 41.7 20.5 34.6 1.5 3.7 9.7 6.8 11.4 4.2 11.4 9.4 7.9 12.8 14.2 12.9 10.4 19.8 7.0 19.7 1.9 23.6 12.6 16.4 16.9 47.9 5.4 3.2 7.2 16.9 38.5 16.9 6.1 21.8 8.2 10.4 52.1 1.0 10.5 8.4 10.0 5.9 4.1 22.7 5.5 24.2 17.4 11.2 0.0 53.4 6.2 5.4 4.1 30.7 9.6 37.8 11.5 24.8 0.8 13.4 1.6 13.4 6.8 1.7 26.3 11.2 15.5 0.9 1.8 5.4 2.0 23.7 2.5 8.7 7.0 17.3 RC3H1 "KIAA2025, RNF198, roquin, RP5-1198E17.5" ENSG00000135870 "Ring finger and CCCH-type domains 1" Q5TC82 1 173931084-174022357 "Enzymes, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027428, HPA027434, HPA027448" Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "Golgi apparatus, Plasma membrane" "HPA027428: AB_10600324, HPA027434: AB_10601235, HPA027448: AB_10601683" "unprognostic (6.91e-2)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" "unprognostic (2.33e-2)" "unprognostic (7.73e-2)" "unprognostic (1.61e-2)" "unprognostic (5.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (5.25e-2)" "unprognostic (2.15e-1)" "unprognostic (3.43e-3)" "unprognostic (6.83e-3)" 4.8 3.8 2.6 4.2 4.7 19.6 5.2 16.0 5.1 4.9 11.4 5.2 3.4 4.5 4.0 6.1 4.8 4.0 4.6 3.1 5.8 3.9 5.8 5.9 4.9 3.5 3.5 5.1 4.8 3.9 4.6 4.3 4.0 4.2 4.2 8.0 4.4 3.5 10.6 7.4 5.5 3.7 2.0 6.7 4.6 5.3 4.1 5.0 5.0 10.3 5.6 4.5 5.1 7.2 6.6 9.1 4.9 7.7 9.2 7.1 6.8 4.4 6.3 5.0 4.4 8.4 7.3 9.4 7.7 7.2 3.9 6.2 7.5 6.3 7.0 6.6 1.8 8.1 6.8 7.0 5.6 10.7 9.1 6.8 4.8 7.3 4.9 4.6 7.9 4.5 9.4 5.6 6.2 5.0 6.5 9.6 8.5 6.1 1.0 7.0 8.8 6.9 8.9 12.7 5.9 5.3 8.4 10.7 4.3 8.2 7.2 10.7 11.4 6.5 6.5 5.6 5.8 6.9 7.5 11.8 4.4 4.8 6.7 3.4 1.9 2.7 1.1 1.9 1.2 1.5 1.1 1.3 1.0 1.8 1.5 1.3 6.4 1.4 2.6 0.8 0.9 0.7 2.6 4.7 16.0 5.1 3.1 5.8 3.5 3.5 4.0 2.0 4.1 7.2 39.8 41.7 34.5 32.0 49.4 34.4 17.3 14.1 60.9 35.6 53.6 28.3 25.7 25.8 20.0 23.9 81.3 10.6 70.2 37.4 9.8 25.4 13.3 77.5 45.9 32.0 34.2 30.7 46.8 18.9 8.2 34.9 68.8 82.9 15.8 20.3 34.2 36.3 11.5 38.7 43.5 28.9 16.2 37.2 48.2 8.1 15.8 38.5 30.2 40.3 33.0 22.7 30.9 42.3 68.2 24.8 22.1 10.5 52.2 38.3 25.1 9.8 30.2 47.3 19.7 39.0 31.5 35.8 14.0 66.8 40.9 11.6 41.4 16.1 25.9 38.5 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favorable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favorable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favorable (7.89e-5)" 8.6 7.0 9.5 7.9 10.2 17.0 16.8 12.6 13.0 9.0 7.7 12.1 8.7 9.6 6.9 7.2 11.9 6.8 16.8 9.4 10.6 16.2 12.3 10.0 9.5 8.9 10.4 14.5 8.3 12.6 5.8 10.0 9.9 10.9 13.2 14.8 12.9 10.1 16.5 5.6 8.6 11.6 9.9 11.5 8.9 13.6 10.7 12.7 18.9 23.6 12.6 7.6 4.7 10.7 9.8 5.0 14.6 13.8 15.1 13.1 8.4 6.5 15.1 13.2 15.4 13.8 11.9 16.2 12.0 9.4 13.1 5.8 37.6 11.5 19.9 13.4 12.3 21.2 9.2 17.9 13.0 28.9 11.2 12.2 14.1 15.2 14.2 15.9 27.0 20.8 19.9 16.2 30.9 15.8 26.7 11.5 24.5 26.9 8.7 14.2 34.4 13.9 20.4 16.7 22.6 12.4 10.7 24.8 28.2 15.9 14.0 12.9 10.8 8.6 8.5 7.8 11.1 17.0 13.0 22.8 10.5 20.2 14.0 27.5 9.2 9.7 4.3 5.7 7.6 4.6 5.4 5.2 8.0 2.1 3.9 5.5 4.0 5.5 5.6 4.1 5.7 4.7 9.5 10.2 12.6 13.0 9.4 10.6 8.9 10.4 9.9 9.9 10.7 10.7 22.2 19.2 10.3 28.4 25.4 40.7 32.3 47.1 39.3 35.0 38.5 25.9 56.8 24.3 23.5 23.9 20.9 31.6 31.2 21.9 68.4 30.3 37.3 11.9 17.1 22.3 13.8 21.8 31.2 22.5 23.2 24.6 21.9 17.3 5.1 23.8 25.4 23.0 19.0 23.5 32.3 23.4 38.7 37.5 26.8 59.8 22.4 27.4 28.4 22.5 23.9 32.0 24.7 31.7 41.0 26.5 22.6 25.2 19.7 36.6 24.6 69.4 13.5 21.7 32.9 20.9 27.3 72.8 41.7 28.1 31.0 33.8 32.9 35.2 27.6 26.3 RCOR2 ENSG00000167771 "REST corepressor 2" Q8IZ40 11 63911230-63917164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 20.7;Excitatory neurons: 5.9;Extravillous trophoblasts: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 35.7;NTERA-2: 47.0;SCLC-21H: 72.6;SH-SY5Y: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021638 Uncertain Approved Nucleoplasm,Vesicles,Midbody Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Vesicles, Midbody" "HPA021638: AB_10960885" "unprognostic (1.96e-2)" "unprognostic (1.15e-1)" "unprognostic (4.10e-2)" "unprognostic (1.98e-3)" "unprognostic (3.10e-2)" "unprognostic (5.86e-2)" "unprognostic (2.33e-4)" "unprognostic (8.64e-2)" "unprognostic (1.46e-1)" "unprognostic (4.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.72e-3)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" "unprognostic (9.93e-2)" "unprognostic (6.06e-3)" 0.3 0.5 1.8 0.2 3.2 0.0 0.4 1.3 3.7 1.4 0.1 1.1 0.8 2.7 1.0 0.4 1.5 0.4 2.8 2.5 1.1 0.6 0.1 0.3 0.0 1.2 1.0 1.2 0.5 1.4 3.5 0.7 0.8 0.9 0.6 3.4 0.9 0.6 1.5 0.3 0.6 1.0 1.1 0.1 0.7 3.2 1.0 0.9 0.2 0.7 0.0 1.2 0.6 2.4 0.0 1.0 35.7 2.5 0.5 2.9 10.9 0.2 0.6 0.5 1.2 1.4 0.3 0.3 0.4 0.8 0.7 0.4 15.8 0.0 0.3 0.6 2.0 0.5 0.3 11.9 5.9 0.0 0.3 3.5 0.0 0.6 0.0 0.0 0.3 4.8 2.0 0.0 0.0 3.3 3.4 13.2 47.0 4.8 0.1 12.4 2.1 1.0 0.1 0.1 72.6 48.7 0.3 3.2 1.8 8.7 2.7 4.5 0.3 0.1 2.3 0.1 0.1 0.3 0.1 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.2 1.3 3.7 2.5 1.1 1.2 1.0 0.8 1.1 1.0 2.4 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 20.7 0.6 0.4 2.2 0.0 0.1 0.0 0.0 0.5 0.0 1.0 0.0 0.1 0.1 0.3 3.3 0.6 1.2 0.0 5.9 0.2 4.4 1.1 0.0 0.6 0.0 1.2 0.0 0.0 0.2 3.3 1.5 1.2 2.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 2.1 1.0 1.0 1.5 0.2 0.2 0.4 0.0 0.0 0.3 0.1 0.2 2.2 0.0 0.3 0.7 0.7 2.9 0.0 0.3 0.8 0.1 1.2 0.8 0.1 RDH8 "PRRDH, SDR28C2" ENSG00000080511 "Retinol dehydrogenase 8" Q9NYR8 19 10013249-10022279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "retina: 114.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.3;Cone photoreceptor cells: 54.2;Early spermatids: 72.6;Muller glia cells: 22.1;Rod photoreceptor cells: 203.4" "Cancer enriched" "Detected in some" 4 "melanoma: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064473 Approved "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Midbody ring, Cytosol" "HPA064473: " "unprognostic (4.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (9.98e-3)" "unprognostic (4.58e-3)" "unprognostic (2.66e-1)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (3.86e-1)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 114.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.3 0.0 0.0 0.2 0.0 0.0 0.0 54.2 0.0 0.0 0.0 0.0 0.0 72.6 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 203.4 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 REPS1 ENSG00000135597 "RALBP1 associated Eps domain containing 1" Q96D71 6 138903493-138988261 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 207.3;Excitatory neurons: 114.3;Inhibitory neurons: 138.1;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029961, HPA029962" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "HPA029961: AB_10603233, HPA029962: AB_2673269" "unprognostic (1.72e-3)" "unprognostic (9.61e-2)" "unprognostic (5.82e-3)" "unprognostic (2.77e-2)" "unprognostic (6.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (9.47e-4)" "unprognostic (3.79e-1)" "unprognostic (2.49e-1)" "unprognostic (9.71e-3)" "unprognostic (4.29e-3)" "unprognostic (4.42e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.69e-2)" 13.5 11.9 24.7 14.9 25.4 23.2 23.6 27.7 36.8 19.2 14.8 17.4 15.4 21.9 40.2 28.0 18.4 14.0 23.9 27.4 24.0 17.4 31.3 15.2 19.4 25.2 23.9 21.1 18.8 41.0 31.7 17.2 21.3 15.9 17.3 38.8 26.1 16.2 17.5 30.0 16.4 19.5 21.5 22.1 18.1 35.6 25.9 36.0 17.8 12.6 22.2 19.5 20.1 25.3 29.3 22.6 42.3 53.1 23.4 41.6 46.2 27.8 30.7 31.9 38.2 54.1 24.8 35.2 22.9 38.9 38.0 33.6 48.7 42.0 42.1 37.6 41.9 29.6 12.9 32.9 35.3 94.6 45.9 34.1 33.7 58.6 70.3 30.2 33.5 51.2 40.2 35.1 41.4 49.4 53.9 51.3 40.4 37.4 21.3 62.4 26.0 20.0 26.5 43.6 37.7 37.2 25.7 38.7 38.0 62.0 18.6 64.4 32.9 17.8 29.6 48.5 38.8 34.4 33.7 49.2 21.1 38.3 26.4 5.9 1.3 1.9 2.2 4.0 3.8 3.0 2.9 3.2 1.9 1.6 2.9 3.6 0.7 2.9 4.5 3.5 3.3 1.2 24.7 25.4 27.7 36.8 27.4 24.0 25.2 23.9 21.3 21.5 25.9 25.3 11.8 19.2 7.4 207.3 18.0 13.4 11.7 7.9 22.2 12.6 13.7 9.5 28.4 10.0 12.2 5.5 16.7 25.6 18.9 11.9 7.9 7.8 13.7 17.5 9.7 10.3 6.0 5.0 114.3 7.1 28.3 11.5 16.3 23.3 15.9 14.4 15.7 43.8 13.3 13.5 138.1 12.8 6.1 24.0 10.3 7.7 7.2 17.2 5.4 47.8 10.5 36.8 15.5 99.5 71.2 8.9 14.7 8.6 23.9 11.2 13.5 8.6 16.5 14.4 19.7 16.8 10.9 41.7 33.8 26.4 14.9 28.6 18.7 7.6 15.2 18.1 RERG MGC15754 ENSG00000134533 "RAS like estrogen regulated growth inhibitor" Q96A58 12 15107783-15348675 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 104.7" "Cell type enhanced" "Detected in many" "Astrocytes: 202.7;Breast glandular cells: 80.1;Inhibitory neurons: 94.3;Sertoli cells: 92.1;Smooth muscle cells: 80.2" "Cancer enhanced" "Detected in all" "breast cancer: 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 15.2;BEWO: 34.1;T-47d: 66.0;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041387 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA041387: AB_10796669" "unprognostic (5.33e-2)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "prognostic unfavorable (7.56e-4)" "unprognostic (8.72e-2)" "unprognostic (9.42e-3)" "unprognostic (2.47e-1)" "unprognostic (2.38e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (5.07e-2)" "unprognostic (2.69e-1)" "unprognostic (7.16e-3)" "unprognostic (2.61e-3)" "unprognostic (3.30e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" 30.7 45.4 8.9 6.8 21.0 0.0 42.5 5.9 16.3 32.0 3.5 37.0 4.1 104.7 50.3 15.1 72.7 11.2 14.0 10.2 12.3 37.0 2.5 16.5 4.3 20.7 12.8 29.0 9.8 4.8 1.4 33.3 21.2 17.0 9.3 0.8 10.2 77.5 5.4 10.2 18.0 83.9 7.7 31.4 20.1 9.0 12.8 2.6 5.8 5.8 2.7 17.4 20.0 9.0 0.0 1.6 0.3 15.2 6.0 0.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.0 0.1 0.0 0.2 0.2 0.0 0.0 4.3 0.1 5.9 0.0 4.7 0.0 1.9 0.8 1.0 0.0 2.3 0.0 0.0 0.0 0.6 0.0 1.4 0.7 0.2 0.3 1.7 0.0 0.9 0.1 0.0 0.2 5.8 0.3 0.1 2.2 2.5 2.6 0.0 1.0 66.0 0.0 0.0 0.9 21.5 0.4 0.0 0.1 5.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 21.0 5.9 16.3 10.2 12.3 20.7 12.8 21.2 7.7 12.8 9.0 10.7 0.0 2.2 202.7 0.4 3.8 8.6 0.9 6.2 1.3 80.1 36.2 1.0 5.7 4.0 7.3 0.0 12.0 0.7 0.0 15.6 9.8 20.9 6.5 9.8 6.0 1.8 0.0 20.2 9.8 14.6 28.7 2.6 1.0 0.0 0.1 2.2 0.0 2.1 3.3 94.3 0.0 18.3 0.0 2.3 16.1 22.1 1.1 7.2 41.2 0.0 5.0 0.0 3.0 1.1 2.2 0.0 32.0 0.0 3.5 0.0 33.7 0.1 0.5 92.1 8.2 80.2 8.3 15.0 12.6 5.5 14.0 1.2 16.1 0.0 5.8 RESF1 "C12orf35, FLJ10652, FLJ20696, GET, KIAA1551, UTA2-1" ENSG00000174718 "Retroelement silencing factor 1" Q9HCM1 12 31959370-31993107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 73.9" "Cell type enhanced" "Detected in some" "Adipocytes: 35.8;B-cells: 43.7;dendritic cells: 88.1;Hofbauer cells: 34.1;Plasma cells: 66.6;T-cells: 21.5" "Cancer enhanced" "Detected in all" "testis cancer: 65.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 212.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 212.8" "Cell line enhanced" "Detected in all" "SuSa: 112.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013816, HPA015622" Approved Supported "Nucleoli,Nucleoli rim,Intermediate filaments,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Nucleoli rim" "Intermediate filaments, Cytosol" "HPA013816: AB_1848661, HPA015622: AB_1848663" "unprognostic (7.97e-3)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (8.49e-2)" "unprognostic (3.21e-1)" "unprognostic (3.09e-3)" "unprognostic (2.24e-1)" "unprognostic (2.19e-1)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (5.04e-9)" "unprognostic (3.83e-1)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (7.26e-3)" 14.3 7.1 2.5 50.7 3.1 21.8 13.9 7.5 10.9 28.9 2.2 14.0 23.8 23.2 9.1 10.6 38.1 19.3 8.1 1.8 3.3 9.1 24.9 17.1 70.2 4.1 2.8 73.9 6.7 9.8 4.0 37.9 5.0 9.2 13.8 7.0 8.2 11.2 4.1 9.1 27.3 16.0 2.0 45.3 20.5 13.2 3.6 60.7 12.6 11.9 62.5 17.7 8.6 5.1 7.6 13.3 22.5 8.6 10.1 12.0 33.6 9.1 9.0 6.0 6.9 50.6 48.9 36.4 21.9 7.6 21.5 9.6 31.3 6.0 8.4 27.1 4.4 51.1 6.7 6.7 19.7 37.0 79.2 6.5 9.0 7.1 11.6 25.4 50.3 24.0 29.5 56.1 6.8 3.7 52.6 15.6 48.3 28.4 5.5 24.1 21.4 16.0 6.3 14.0 9.0 8.1 11.7 6.0 6.0 112.9 20.8 40.5 32.0 6.7 10.4 11.5 9.6 33.9 38.1 44.8 3.6 20.6 7.4 55.5 14.7 15.4 42.2 16.1 40.3 33.6 38.0 40.7 12.3 26.8 44.1 43.8 212.8 30.6 18.1 7.7 38.9 20.4 2.5 3.1 7.5 10.9 1.8 3.3 4.1 2.8 5.0 2.0 3.6 5.1 35.8 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 15.0 88.1 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 5.1 21.5 0.0 0.0 0.0 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RETREG3 "DKFZp686B1036, FAM134C, FLJ33806" ENSG00000141699 "Reticulophagy regulator family member 3" Q86VR2 17 42579513-42610623 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.8;Collecting duct cells: 31.3;Pancreatic endocrine cells: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016492 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear membrane" Cytosol "HPA016492: AB_1853027" "unprognostic (6.79e-2)" "unprognostic (1.29e-2)" "unprognostic (2.78e-1)" "prognostic favorable (1.61e-4)" "unprognostic (5.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.53e-2)" "unprognostic (2.21e-1)" "unprognostic (2.61e-1)" "unprognostic (2.58e-2)" "unprognostic (1.00e-2)" "unprognostic (2.51e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.24e-1)" "unprognostic (5.68e-1)" "unprognostic (9.64e-3)" "unprognostic (5.43e-2)" 16.2 21.7 17.3 13.2 16.6 6.9 16.9 16.4 18.9 23.0 18.7 19.0 14.2 18.5 21.3 29.2 16.8 10.9 16.2 17.0 17.4 19.5 33.4 17.4 19.5 16.9 18.0 19.6 39.9 18.9 20.4 20.9 17.7 25.5 16.8 31.4 23.2 14.0 22.4 33.9 20.7 15.1 16.8 30.1 22.8 38.7 19.1 20.6 16.3 16.4 21.6 19.4 23.1 15.0 12.0 36.6 15.8 25.8 39.6 21.9 22.5 16.9 22.7 19.6 22.9 17.5 25.3 26.3 23.1 27.5 20.1 45.9 20.5 25.3 18.9 28.2 19.3 10.7 22.2 31.0 27.2 18.6 26.5 33.6 34.2 21.5 21.8 21.7 21.3 19.0 22.3 25.4 15.7 20.7 27.5 26.9 10.0 22.5 9.0 14.7 24.2 27.2 22.5 38.2 28.2 19.3 18.1 14.6 26.1 28.9 41.5 14.2 27.2 21.0 12.8 21.1 16.2 43.4 55.3 22.7 19.3 11.6 16.2 54.9 16.2 36.4 44.5 19.2 39.1 23.7 36.5 42.9 15.1 24.8 35.1 40.4 13.8 28.2 24.1 15.0 57.0 36.4 17.3 16.6 16.4 18.9 17.0 17.4 16.9 18.0 17.7 16.8 19.1 15.0 16.7 25.6 29.8 0.0 8.8 0.0 0.0 0.0 0.0 0.0 21.7 18.3 0.0 0.0 6.2 31.3 0.0 22.4 24.7 0.0 7.9 16.4 0.0 14.5 16.7 7.4 0.0 0.0 0.0 25.4 16.0 7.4 0.0 20.0 7.6 26.8 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 7.2 0.0 0.0 0.0 0.0 33.8 0.0 0.0 8.8 0.0 0.0 13.4 5.1 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 20.4 8.1 17.3 0.0 0.0 REXO2 "CGI-114, DKFZP566E144, SFN" ENSG00000076043 "RNA exonuclease 2" Q9Y3B8 11 114439435-114450279 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038450, HPA038451" Enhanced Supported "Nucleoli,Focal adhesion sites,Mitochondria" NA NA 340000 "Cluster 6: Non-specific - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "Nucleoli, Focal adhesion sites" "HPA038450: AB_10672516, HPA038451: AB_10697391" "unprognostic (3.26e-3)" "unprognostic (2.36e-2)" "prognostic favorable (6.51e-4)" "unprognostic (6.84e-3)" "unprognostic (5.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.78e-1)" "unprognostic (8.18e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.73e-2)" "unprognostic (6.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.69e-2)" "prognostic unfavorable (6.70e-4)" 51.1 57.2 23.5 40.3 25.9 55.0 57.1 26.3 31.5 73.4 28.6 80.4 24.3 71.5 46.5 65.8 38.1 47.8 140.3 24.0 29.5 102.5 50.2 42.0 32.5 30.3 28.1 69.0 45.5 154.5 32.5 56.9 29.7 72.5 47.2 9.2 115.3 58.0 40.8 50.5 33.1 106.7 26.6 44.8 65.4 53.5 25.7 30.4 36.5 40.5 37.1 68.3 64.4 29.9 159.3 92.7 32.1 88.4 254.6 268.7 81.9 266.3 192.9 122.6 155.4 244.9 261.2 88.8 258.2 220.8 185.4 97.4 74.1 219.5 201.5 86.9 61.3 98.1 136.0 144.7 339.2 72.3 29.5 190.8 206.0 157.4 163.7 214.1 223.1 84.7 183.9 48.6 278.5 38.7 49.4 84.0 102.3 119.1 160.3 45.7 112.1 317.1 177.0 126.9 59.8 38.5 122.7 86.7 110.8 134.8 184.9 35.6 231.4 162.5 194.2 124.0 161.6 39.7 52.4 146.3 111.3 165.2 89.7 64.3 14.0 21.3 32.2 19.2 37.2 37.6 47.9 41.1 18.8 29.2 43.0 35.1 3.5 45.2 20.6 70.1 75.3 29.1 23.5 25.9 26.3 31.5 24.0 29.5 30.3 28.1 29.7 26.6 25.7 29.9 82.9 105.8 56.4 20.9 42.3 138.9 146.5 189.1 88.2 14.9 99.2 100.6 370.0 47.1 126.5 95.6 2.1 171.6 55.3 27.2 277.8 126.6 83.6 75.3 110.8 98.4 80.9 315.2 20.0 70.7 188.5 176.8 48.4 85.2 31.8 40.1 89.6 80.0 98.2 5.0 17.4 82.9 89.5 21.0 56.7 48.1 210.6 33.9 241.9 15.9 41.9 36.5 29.9 25.1 33.5 110.0 33.7 176.8 103.8 199.6 26.7 371.4 126.5 8.3 52.6 90.6 177.0 237.3 82.1 119.9 162.7 269.1 47.5 120.6 72.4 130.4 REXO5 NEF-sp ENSG00000005189 "RNA exonuclease 5" Q96IC2 16 20806429-20849665 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 343.8" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 15 "basophil: 86.7" "Lineage enriched" "Detected in many" 39 "granulocytes: 86.7" "Cell line enhanced" "Detected in many" "K-562: 44.7;U-266/70: 42.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040755, HPA040868, HPA066145" Approved Approved "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA040755: AB_10965790, HPA040868: AB_10963549, HPA066145: " "unprognostic (2.39e-1)" "unprognostic (2.09e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (6.24e-2)" "unprognostic (2.26e-1)" "unprognostic (1.80e-2)" "unprognostic (8.24e-2)" "unprognostic (4.72e-2)" "unprognostic (2.42e-4)" "unprognostic (1.01e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.93e-2)" 2.3 1.8 1.4 1.8 1.4 11.6 3.6 1.6 2.0 1.7 0.4 2.1 2.9 2.2 1.2 2.3 4.2 1.6 3.4 1.4 2.3 1.2 1.8 1.0 2.9 1.7 1.1 1.9 1.7 40.0 0.9 1.5 1.6 5.3 3.0 4.2 1.7 1.3 1.0 2.2 2.1 2.7 0.8 1.0 5.0 343.8 2.2 7.4 0.9 1.3 2.6 2.0 1.6 2.1 11.3 6.5 10.1 4.5 4.2 7.5 3.4 7.6 8.4 8.2 8.9 4.7 10.0 7.0 11.5 6.7 5.7 5.7 7.7 3.4 8.5 6.5 4.9 11.7 10.2 6.7 0.8 17.2 16.4 3.8 1.5 9.7 12.4 3.5 2.8 0.0 44.7 29.8 20.5 15.1 2.8 13.5 5.5 4.6 6.6 14.0 18.8 12.6 2.5 4.0 8.6 9.7 7.3 9.6 2.4 2.9 16.2 14.8 1.4 6.1 5.4 8.2 9.3 42.5 31.1 2.7 12.6 22.3 5.6 86.7 0.4 5.7 0.3 0.1 0.4 0.0 0.4 0.4 0.7 0.0 0.1 0.3 0.4 2.2 0.2 0.2 1.8 0.4 1.4 1.4 1.6 2.0 1.4 2.3 1.7 1.1 1.6 0.8 2.2 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 0.0 1.3 0.0 0.0 3.2 0.8 0.0 0.0 1.6 0.0 2.8 1.6 0.6 0.0 0.0 0.0 1.5 2.4 1.5 0.0 1.7 1.3 26.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.5 4.7 0.0 0.0 RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Adipocytes: 101.3;Endothelial cells: 51.1;Hofbauer cells: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 201.5" "Lineage enriched" "Detected in many" 21 "granulocytes: 201.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 95.5;HMC-1: 222.1;NB-4: 74.8;U-937: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: AB_2673643, HPA060388: AB_2732649" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.87e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-3)" 19.8 5.9 2.4 7.4 2.5 77.9 15.6 2.3 2.8 8.7 10.1 13.7 3.2 10.1 3.5 3.1 7.1 4.6 12.8 3.3 2.2 8.6 3.5 13.3 5.4 2.5 2.4 5.7 3.5 3.9 4.3 10.4 2.2 9.5 1.9 1.5 4.1 2.8 7.9 6.3 9.6 6.1 2.7 10.5 8.6 3.7 2.4 16.7 8.2 3.9 4.8 11.8 5.4 2.1 30.5 8.0 4.0 18.9 13.0 9.4 20.8 48.8 21.4 15.8 7.7 0.5 1.1 0.0 1.2 95.5 7.0 3.0 11.2 1.1 14.5 0.2 6.5 1.3 1.5 2.2 19.0 11.4 222.1 5.2 0.3 5.0 1.9 6.1 16.0 4.8 4.7 0.3 18.1 0.4 0.6 74.8 8.6 0.8 0.3 3.2 8.6 0.0 2.9 0.1 0.3 43.6 19.8 0.0 17.6 14.9 0.4 34.7 3.2 12.4 11.0 7.5 0.1 7.1 7.7 0.0 0.2 64.1 19.5 201.5 6.9 80.7 6.1 5.4 6.2 0.1 6.1 5.2 2.1 0.1 9.7 8.7 35.5 2.2 7.3 9.1 4.3 3.8 2.4 2.5 2.3 2.8 3.3 2.2 2.5 2.4 2.2 2.7 2.4 2.1 101.3 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 3.1 7.4 0.0 0.0 1.8 1.8 0.0 0.8 16.5 0.0 0.0 1.1 0.0 2.3 1.9 51.1 0.0 0.0 0.0 0.9 1.2 9.2 0.0 6.0 1.3 12.5 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.9 0.0 0.0 5.9 0.0 0.0 0.5 1.5 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.5 10.7 4.2 0.0 0.0 RFX2 FLJ14226 ENSG00000087903 "Regulatory factor X2" P48378 19 5993164-6199572 "Predicted intracellular proteins, Transcription factors" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 56.9" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Early spermatids: 163.7;Late spermatids: 196.2;Respiratory ciliated cells: 103.8;Spermatocytes: 113.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 23.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 23.6" "Cell line enhanced" "Detected in many" "HMC-1: 19.4;SCLC-21H: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048969 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA048969: AB_2680577" "unprognostic (1.31e-1)" "prognostic favorable (2.80e-4)" "unprognostic (6.72e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.37e-1)" "unprognostic (4.15e-2)" "unprognostic (1.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.86e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (2.50e-2)" "unprognostic (1.07e-1)" 9.8 2.0 9.0 2.2 8.0 9.5 6.9 12.1 8.1 5.9 35.2 19.4 3.3 16.2 1.2 8.0 20.8 5.0 7.8 10.4 8.7 2.2 1.7 10.5 1.5 15.5 21.2 6.7 4.4 1.8 10.4 0.9 12.7 6.0 1.8 1.3 3.2 2.3 2.0 11.2 8.8 5.3 15.4 2.9 7.0 56.9 12.7 4.2 3.5 0.6 1.6 9.6 6.3 11.7 5.3 3.9 6.2 12.3 3.2 1.9 3.9 3.3 4.3 2.6 4.1 1.8 6.0 5.7 3.4 4.1 5.7 7.6 1.6 6.2 3.6 1.4 0.9 8.8 4.0 1.8 3.6 4.1 19.4 2.2 5.3 5.8 3.0 3.1 4.0 7.7 6.0 0.2 2.6 2.6 7.7 5.5 1.7 6.8 2.6 2.1 3.9 0.6 3.3 9.5 24.2 3.4 3.0 2.4 1.7 0.6 4.2 4.3 6.1 1.1 5.6 4.3 3.3 8.2 2.9 3.3 3.2 14.4 2.3 0.0 2.7 1.1 0.1 0.5 0.0 0.4 0.5 0.3 2.1 0.2 0.5 0.6 23.6 0.7 1.6 0.0 0.1 0.8 9.0 8.0 12.1 8.1 10.4 8.7 15.5 21.2 12.7 15.4 12.7 11.7 12.0 25.6 31.6 84.2 2.6 26.4 33.7 11.5 12.5 3.6 8.5 10.9 7.6 15.7 26.0 3.7 2.1 5.9 2.0 4.1 3.9 5.6 163.7 69.0 9.5 13.2 13.8 6.5 5.2 1.8 8.8 23.0 2.6 4.7 46.2 14.7 12.1 2.8 7.0 0.0 5.5 4.4 2.0 6.2 17.3 196.2 8.1 13.0 7.2 8.4 5.1 5.7 5.2 3.0 1.8 3.5 1.6 4.1 2.4 7.9 4.6 2.1 103.8 3.5 26.3 49.2 11.4 113.2 13.5 6.3 22.0 5.6 5.6 2.6 5.1 22.0 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "retina: 139.0" "Cell type enriched" "Detected in some" 29 "Muller glia cells: 1475.8" "Cancer enriched" "Detected in single" 4 "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 23.4;olfactory bulb: 49.7;thalamus: 27.3" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (9.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" 0.2 0.0 11.9 0.0 11.9 0.0 0.1 4.4 14.6 0.0 14.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 7.4 8.5 0.0 0.0 0.2 0.0 5.2 8.2 0.0 0.0 0.0 0.4 0.0 5.4 0.0 0.0 139.0 0.1 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 11.9 4.4 14.6 7.4 8.5 5.2 8.2 5.4 3.1 10.1 6.2 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.0 0.0 20.6 0.1 0.1 0.4 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 10.6 0.3 0.0 0.0 0.0 0.0 1475.8 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.6 0.0 2.8 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RGS12 ENSG00000159788 "Regulator of G protein signaling 12" O14924 4 3293028-3439913 "Plasma proteins, Predicted intracellular proteins" Transcription "GTPase activation, Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 142.0;Inhibitory neurons: 170.1;Suprabasal keratinocytes: 110.0;Urothelial cells: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054646, HPA067421" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" Cytosol "HPA054646: AB_2682555, HPA067421: AB_2685836" "unprognostic (2.08e-1)" "unprognostic (1.71e-3)" "unprognostic (7.50e-2)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.03e-4)" "unprognostic (3.43e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" "unprognostic (9.02e-2)" "unprognostic (1.70e-2)" "unprognostic (2.13e-1)" "prognostic favorable (8.43e-4)" "unprognostic (2.54e-1)" "unprognostic (2.60e-1)" "unprognostic (5.92e-2)" "unprognostic (1.11e-2)" 8.4 6.5 13.6 2.9 46.6 2.3 8.7 10.2 20.5 16.1 10.5 8.3 4.8 8.6 4.7 30.4 9.9 3.9 6.7 12.9 8.5 11.1 17.3 10.6 3.5 9.5 8.5 12.5 4.9 3.3 13.8 3.7 8.2 16.6 1.9 3.8 9.4 4.7 12.3 20.7 6.2 2.6 7.8 6.0 6.7 10.3 8.7 3.6 8.0 4.6 3.3 10.4 20.2 10.5 4.8 6.0 11.9 8.6 3.9 3.1 4.9 5.1 4.1 5.2 3.8 4.9 2.8 1.1 3.1 4.5 7.6 4.6 2.3 16.3 1.7 0.1 1.9 0.5 3.6 12.0 3.5 0.3 6.5 2.6 10.9 2.7 3.6 4.6 11.5 4.2 5.6 0.2 4.8 4.1 0.8 13.1 5.6 2.7 5.7 12.3 4.6 4.0 2.7 14.1 13.3 13.8 3.2 2.2 11.4 2.9 5.4 8.2 8.7 10.0 6.5 2.0 5.5 5.9 4.9 2.7 5.9 7.2 7.3 0.4 0.3 0.0 0.2 1.1 0.0 0.0 0.2 0.1 0.4 0.2 0.3 0.1 0.4 0.0 1.1 0.2 0.2 0.2 13.6 46.6 10.2 20.5 12.9 8.5 9.5 8.5 8.2 7.8 8.7 10.5 16.1 6.4 6.4 66.9 2.6 84.4 142.0 69.3 71.2 17.3 11.0 14.9 8.6 8.6 28.6 5.5 29.2 6.2 1.3 6.4 3.9 10.4 5.0 22.8 13.3 26.6 14.9 4.8 44.3 10.4 1.3 14.6 7.7 11.8 14.0 57.7 27.8 28.8 20.8 10.1 170.1 10.8 8.2 12.4 11.3 5.5 14.9 21.7 17.8 47.8 7.8 29.3 2.1 71.4 25.5 14.7 2.7 7.9 0.8 53.9 6.0 23.9 34.6 18.9 0.0 12.5 12.7 24.0 15.3 84.4 110.0 6.7 4.3 11.8 9.0 153.8 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 619.6;Late spermatids: 1623.3" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" 2.7 0.9 1.7 0.0 2.4 0.0 0.6 1.0 1.5 1.4 10.4 0.3 0.0 2.9 1.1 0.3 10.6 1.2 0.3 1.1 3.9 0.2 0.1 1.7 0.3 5.9 7.4 7.3 0.5 0.0 1.1 0.5 3.7 1.3 0.1 1.0 0.1 2.3 0.1 0.6 0.1 1.5 3.7 0.0 0.1 61.3 5.3 0.1 0.3 0.1 0.3 0.4 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.3 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.0 1.5 1.1 3.9 5.9 7.4 3.7 3.7 5.3 2.9 0.1 0.0 0.0 14.4 0.0 2.2 0.0 1.6 0.6 1.2 1.2 0.8 0.8 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 619.6 58.1 14.2 0.7 0.0 0.0 2.3 0.0 0.2 8.6 0.5 0.8 0.0 1.3 0.0 0.0 0.2 0.0 1.6 0.0 4.1 0.0 2.9 1623.3 131.4 0.4 0.0 6.5 0.0 10.9 0.0 20.1 2.5 0.0 0.0 62.8 0.0 0.0 0.0 0.0 77.2 0.2 0.0 0.4 1.6 70.9 11.1 0.1 2.0 0.8 0.4 8.3 0.0 0.1 RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 97.3;Early spermatids: 173.5;Excitatory neurons: 652.7;Inhibitory neurons: 256.1;Late spermatids: 298.0" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 11.5;Karpas-707: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" 4.7 0.2 1.1 0.6 2.2 1.4 4.0 0.6 8.6 4.9 0.0 1.0 0.3 1.4 2.6 0.4 2.2 1.2 11.2 3.5 2.8 2.6 0.1 0.9 0.1 19.2 16.0 1.2 0.2 8.1 1.7 3.0 20.2 0.4 1.0 1.7 0.8 1.4 1.1 0.9 0.8 1.3 5.4 0.9 0.4 10.6 6.4 0.3 5.7 0.8 0.5 0.7 0.9 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 40.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.3 1.2 1.1 2.2 0.6 8.6 3.5 2.8 19.2 16.0 20.2 5.4 6.4 3.4 5.8 0.0 0.0 97.3 0.2 0.3 0.0 0.0 0.0 2.2 2.1 2.4 22.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 173.5 2.8 0.9 2.6 0.0 5.3 652.7 0.2 0.1 3.1 0.0 7.1 0.0 0.4 0.0 0.0 0.2 0.0 256.1 0.0 0.0 0.0 0.0 298.0 1.8 8.3 0.0 44.0 5.1 0.0 0.0 36.2 8.9 0.0 0.0 7.5 0.2 0.0 0.0 0.4 0.0 0.4 13.1 0.4 18.6 2.3 1.3 0.2 0.1 0.8 0.5 0.1 0.0 0.7 RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 122.5;Inhibitory neurons: 170.6;Oligodendrocyte precursor cells: 67.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 26.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HUVEC TERT2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (2.93e-1)" "unprognostic (3.39e-1)" "unprognostic (7.35e-2)" "unprognostic (4.77e-2)" "unprognostic (7.57e-2)" "unprognostic (8.59e-2)" "unprognostic (5.22e-2)" "unprognostic (8.81e-3)" "unprognostic (1.86e-2)" "unprognostic (7.64e-2)" "unprognostic (5.49e-3)" "unprognostic (1.83e-1)" "unprognostic (1.65e-3)" "unprognostic (3.39e-3)" "unprognostic (2.06e-3)" "unprognostic (6.46e-2)" "unprognostic (8.50e-3)" 1.9 3.2 3.2 0.5 12.2 0.0 0.5 1.0 26.0 4.0 0.0 0.6 0.9 2.3 3.7 1.7 7.8 1.7 2.6 7.2 1.2 2.0 1.0 1.4 0.3 0.2 3.3 2.4 0.2 0.1 0.8 0.0 0.0 5.3 0.7 4.8 1.8 7.4 0.1 0.3 1.0 1.4 0.0 0.7 0.8 0.8 10.2 0.0 0.3 1.0 0.1 0.9 0.5 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 12.2 1.0 26.0 7.2 1.2 0.2 3.3 0.0 0.0 10.2 5.0 0.4 0.0 0.0 5.5 0.1 0.0 0.1 0.1 0.6 6.5 0.7 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 5.1 4.6 0.0 2.7 122.5 0.0 0.0 0.8 0.0 4.7 0.0 0.1 23.2 0.1 0.0 0.0 170.6 0.0 0.0 0.3 0.0 1.9 7.2 0.1 0.0 12.2 0.0 3.6 0.0 67.8 6.4 0.0 0.0 13.9 0.0 0.1 0.0 0.2 2.2 2.1 6.6 0.1 13.2 0.3 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.2 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RIF1 "FLJ10599, FLJ12870" ENSG00000080345 "Replication timing regulatory factor 1" Q5UIP0 2 151409883-151508013 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036887, HPA036888" Supported Uncertain "Nucleoplasm,Nuclear bodies,Plasma membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA036887: AB_2675361, HPA036888: AB_2675362" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.71e-1)" "unprognostic (4.71e-3)" "unprognostic (5.87e-2)" "unprognostic (1.79e-2)" "unprognostic (3.73e-2)" "unprognostic (1.86e-1)" "unprognostic (2.51e-2)" "unprognostic (2.84e-2)" "unprognostic (1.80e-3)" "unprognostic (4.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (2.22e-1)" "unprognostic (1.57e-2)" "unprognostic (8.41e-2)" 6.1 5.0 4.4 7.4 8.4 21.7 10.0 13.8 7.0 6.5 2.6 5.6 4.3 8.2 4.0 5.6 5.6 5.6 3.5 4.6 5.1 5.5 6.7 5.1 8.5 4.4 5.1 11.2 7.0 6.8 3.5 8.0 5.4 6.0 6.1 8.2 7.7 5.0 7.5 7.2 4.6 6.2 4.9 6.5 6.1 11.0 4.5 10.7 9.1 9.5 7.9 7.3 4.6 13.8 20.8 17.4 26.8 20.5 10.7 13.8 25.9 24.8 18.0 21.6 25.5 28.9 16.4 39.2 21.7 17.3 17.9 21.3 41.2 17.1 36.1 27.8 19.8 63.4 21.4 21.0 11.2 64.7 20.2 10.3 11.3 38.8 28.7 12.3 21.3 23.5 52.2 32.6 22.1 13.8 38.3 22.9 43.2 11.2 22.9 38.4 42.1 26.1 11.6 24.9 24.2 18.8 32.0 14.6 16.5 18.8 12.9 23.1 27.0 32.9 22.8 20.3 26.7 16.0 29.6 55.4 15.3 25.5 22.5 6.3 2.5 3.0 4.3 1.7 4.9 4.0 3.6 3.2 1.8 3.1 4.8 3.7 2.8 7.7 3.5 1.6 2.8 1.7 4.4 8.4 13.8 7.0 4.6 5.1 4.4 5.1 5.4 4.9 4.5 13.8 53.1 96.1 49.7 41.1 43.5 49.3 47.5 21.9 33.0 48.2 30.4 29.8 38.2 28.6 38.0 14.7 31.3 39.2 40.3 19.6 1.9 38.5 22.6 38.0 61.7 48.0 25.0 84.3 68.5 21.9 35.9 51.3 34.7 65.0 34.1 88.6 27.1 19.7 23.0 47.1 72.4 30.9 14.2 26.4 27.0 14.0 43.8 37.6 30.2 48.7 44.1 35.8 32.0 73.9 126.3 29.9 23.5 34.3 45.1 53.2 14.9 12.9 21.3 42.8 85.5 106.5 51.2 122.8 113.1 28.9 41.6 40.9 45.3 58.9 34.6 45.4 RILPL1 FLJ39378 ENSG00000188026 "Rab interacting lysosomal protein like 1" Q5EBL4 12 123470054-123533719 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 62.4;skeletal muscle: 88.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041314 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041314: AB_10795587" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (3.71e-2)" "unprognostic (5.36e-2)" "unprognostic (3.12e-2)" "unprognostic (2.99e-3)" "unprognostic (1.94e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (2.30e-2)" "unprognostic (8.30e-2)" "unprognostic (4.25e-2)" "unprognostic (2.98e-1)" "unprognostic (2.32e-1)" "unprognostic (6.07e-3)" "unprognostic (2.81e-1)" 7.8 9.0 17.1 3.1 21.1 2.6 7.5 18.6 18.3 10.7 17.9 10.5 1.3 12.0 4.1 5.1 9.5 3.4 62.4 15.2 16.7 6.8 4.2 6.8 1.8 19.0 19.7 8.5 3.7 6.6 6.4 7.3 18.6 9.1 1.4 3.0 6.8 7.4 88.9 6.8 4.2 6.3 15.9 4.4 5.5 4.1 18.0 1.5 13.3 41.1 1.0 9.5 7.5 27.1 8.3 11.4 10.1 7.9 11.1 10.4 10.6 14.6 8.1 7.8 6.9 7.1 1.9 0.3 7.1 14.3 5.6 8.9 7.5 7.0 3.1 8.4 13.8 1.1 8.1 10.6 19.4 0.4 3.0 11.9 13.6 8.7 12.5 19.5 8.0 1.5 6.6 0.4 8.0 13.8 0.9 2.7 7.4 2.4 11.9 1.3 5.5 0.4 5.6 8.5 1.6 9.3 7.8 6.7 17.9 5.5 9.0 0.2 16.0 10.2 5.1 14.8 9.4 1.7 0.9 0.2 10.4 0.0 6.5 0.4 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.5 0.4 1.1 0.3 0.3 0.3 0.2 0.2 17.1 21.1 18.6 18.3 15.2 16.7 19.0 19.7 18.6 15.9 18.0 27.1 13.0 38.5 11.7 32.3 0.7 4.6 5.1 3.4 6.2 14.1 4.6 14.7 9.8 4.3 7.2 11.0 6.2 9.1 0.7 0.2 1.9 2.2 1.8 6.3 18.0 8.5 0.0 0.0 28.8 2.2 6.2 9.4 1.1 7.4 1.3 18.9 9.7 1.6 5.7 23.5 16.4 1.3 0.0 1.3 2.4 1.6 15.5 3.3 5.4 18.7 0.9 21.4 0.0 13.6 64.9 2.2 0.5 8.2 0.3 5.1 0.1 2.6 4.1 6.4 6.6 14.4 9.9 0.9 2.9 2.3 3.8 9.3 2.0 21.5 0.7 3.3 RIMBP2 "KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2" ENSG00000060709 "RIMS binding protein 2" O15034 12 130396137-130716281 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9;parathyroid gland: 24.6;pituitary gland: 32.2" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 75.5;Excitatory neurons: 128.2;Inhibitory neurons: 191.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 28.9;SH-SY5Y: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041494, HPA044114" Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041494: , HPA044114: AB_2678815" "unprognostic (4.15e-4)" "unprognostic (9.77e-3)" "unprognostic (1.20e-1)" "unprognostic (6.45e-2)" "unprognostic (1.91e-3)" "unprognostic (3.63e-1)" "unprognostic (1.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (6.82e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.86e-1)" "unprognostic (6.41e-3)" "unprognostic (5.27e-2)" "unprognostic (2.07e-1)" "unprognostic (1.03e-1)" "unprognostic (4.73e-2)" 0.6 14.5 6.3 0.9 11.3 0.2 0.2 0.0 17.5 7.2 17.3 1.5 2.9 2.7 2.5 0.5 7.8 0.9 0.0 25.9 19.2 5.9 0.2 0.4 0.1 1.7 19.6 2.1 2.5 24.6 32.2 0.0 20.6 1.1 1.8 11.2 0.3 1.3 0.2 2.7 2.5 2.4 0.1 1.0 5.9 2.6 0.9 0.3 0.6 3.9 0.1 0.3 0.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.0 0.4 7.3 0.0 0.0 28.9 55.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 11.3 0.0 17.5 25.9 19.2 1.7 19.6 20.6 0.1 0.9 2.7 0.4 0.0 0.0 5.9 0.0 2.0 0.1 0.0 0.6 19.4 0.0 0.1 1.4 0.0 0.0 0.0 31.3 0.0 0.0 0.4 0.0 0.0 3.8 3.0 1.4 0.4 75.5 0.0 128.2 0.0 0.0 0.7 4.1 6.4 0.0 0.0 0.0 0.0 0.0 10.1 191.4 2.6 6.1 0.0 0.5 2.1 0.9 0.0 0.0 1.0 0.0 3.2 0.0 19.6 5.3 0.1 0.1 0.7 0.0 0.1 0.0 0.1 0.7 14.0 0.0 0.0 0.2 1.7 1.5 0.1 0.6 0.0 0.1 0.0 0.8 0.0 RIMS3 "NIM3, RIM3" ENSG00000117016 "Regulating synaptic membrane exocytosis 3" Q9UJD0 1 40620680-40665682 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 105.9" "Cell type enhanced" "Detected in many" "Early spermatids: 12.6;Excitatory neurons: 37.7;Inhibitory neurons: 21.1;Late spermatids: 34.4;Muller glia cells: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 77.4;JURKAT: 26.7;SH-SY5Y: 35.2;U-87 MG: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055285 Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Mitochondria" Nucleoplasm "HPA055285: AB_2682771" "unprognostic (3.51e-3)" "unprognostic (7.18e-3)" "unprognostic (4.44e-3)" "unprognostic (1.44e-4)" "unprognostic (3.70e-1)" "unprognostic (2.88e-2)" "unprognostic (1.44e-5)" "unprognostic (2.41e-1)" "unprognostic (1.53e-1)" "unprognostic (2.87e-1)" "unprognostic (2.54e-1)" "unprognostic (7.93e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-1)" "unprognostic (3.25e-2)" "unprognostic (3.11e-2)" "unprognostic (2.19e-2)" 1.0 6.2 33.4 1.9 63.8 3.6 2.5 0.0 80.2 1.6 0.0 4.4 0.6 3.5 1.6 2.3 2.7 0.9 2.1 27.0 29.3 1.4 0.4 3.5 1.7 0.7 38.1 1.8 0.7 2.9 1.0 3.2 0.4 2.5 3.1 6.5 1.6 3.3 0.3 2.2 2.2 4.1 2.8 1.2 3.4 3.7 105.9 4.3 2.2 0.5 2.3 2.5 1.5 30.2 4.1 1.6 5.8 6.2 0.3 0.0 0.9 0.1 0.1 1.0 1.2 0.7 1.2 77.4 0.1 0.1 2.8 0.7 3.8 0.7 0.6 13.5 1.9 4.4 0.5 2.1 0.2 0.7 3.5 0.1 3.1 0.2 0.2 0.2 0.3 26.7 3.8 2.9 0.0 7.0 11.7 0.4 3.8 0.7 0.4 5.3 5.3 14.3 1.1 1.0 19.9 35.2 0.8 3.7 2.6 7.7 0.9 21.4 0.1 0.6 5.9 0.1 1.1 0.7 5.9 16.8 32.2 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 33.4 63.8 0.0 80.2 27.0 29.3 0.7 38.1 0.4 2.8 105.9 30.2 0.0 6.4 0.0 2.6 0.4 0.5 0.2 0.1 0.6 6.1 1.5 2.5 1.8 0.0 0.1 1.8 0.0 0.1 7.3 6.0 0.0 0.9 12.6 0.0 0.0 0.5 0.0 1.3 37.7 1.5 0.1 0.5 0.0 0.1 1.3 10.7 0.0 0.0 2.7 5.0 21.1 4.2 0.0 2.6 1.4 34.4 0.0 1.5 0.0 3.7 0.9 13.4 0.0 4.0 4.5 2.3 1.4 0.7 0.2 0.4 0.0 0.7 0.0 0.7 0.0 1.5 2.5 2.7 2.0 0.1 0.1 0.3 0.9 0.7 1.6 0.2 RIN2 RASSF4 ENSG00000132669 "Ras and Rab interactor 2" Q8WYP3 20 19757606-20002457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 198.5;Microglial cells: 191.1;Oligodendrocyte precursor cells: 296.6;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034641 Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoli, Golgi apparatus" "HPA034641: AB_10671230" "unprognostic (8.23e-3)" "unprognostic (8.09e-3)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.12e-2)" "unprognostic (3.86e-2)" "unprognostic (1.61e-2)" "unprognostic (3.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.78e-3)" "unprognostic (2.49e-1)" "unprognostic (6.27e-2)" "prognostic favorable (8.34e-6)" "unprognostic (3.10e-1)" "unprognostic (2.08e-2)" "unprognostic (8.02e-3)" "unprognostic (3.63e-2)" 14.2 6.4 8.7 8.6 13.5 6.1 9.5 9.4 7.1 14.4 14.4 12.5 13.3 14.1 3.9 13.6 11.7 17.8 18.7 9.5 10.8 12.1 5.3 18.3 4.7 14.6 13.2 15.0 6.5 4.6 1.4 19.8 12.8 9.4 12.7 5.5 15.6 13.5 9.4 8.2 14.7 16.2 9.5 16.8 8.8 1.8 12.7 3.0 13.7 13.2 5.3 8.1 3.8 14.0 6.7 22.4 4.1 13.7 23.3 14.2 13.1 5.9 22.8 5.7 3.0 10.0 5.8 0.0 24.0 14.6 10.6 24.7 0.1 33.5 6.3 2.7 0.1 0.0 3.5 0.8 5.4 0.0 0.1 21.7 6.1 10.7 11.9 13.4 30.6 0.0 0.1 0.4 17.0 5.3 0.1 0.4 0.7 3.2 47.1 0.1 13.8 3.4 7.2 9.2 3.5 0.9 5.3 23.7 0.1 4.1 2.0 1.4 33.7 11.4 2.9 8.1 9.2 0.1 0.1 0.0 8.0 0.0 2.0 0.2 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 1.0 0.1 0.0 0.4 8.7 13.5 9.4 7.1 9.5 10.8 14.6 13.2 12.8 9.5 12.7 14.0 52.3 64.1 17.5 198.5 1.4 41.9 18.5 30.9 24.5 6.1 25.6 18.4 34.3 14.3 23.7 31.3 8.4 6.8 0.2 30.4 43.0 17.5 1.0 50.0 47.3 52.7 14.4 0.4 5.9 34.5 7.4 33.2 10.7 87.3 0.0 32.4 105.3 4.2 100.2 6.7 82.8 17.2 26.4 60.3 40.3 0.8 19.3 37.7 21.4 191.1 21.4 33.2 1.0 296.6 202.4 26.2 10.5 15.4 0.8 22.3 23.0 50.1 27.1 1.9 0.0 25.4 22.6 0.5 0.8 33.6 54.0 7.1 2.9 43.1 21.9 32.2 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23453287-23486603 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 174.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.10e-4)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 23.1 18.5 5.5 20.4 7.1 174.3 19.2 7.9 10.2 17.4 8.3 47.5 51.6 16.7 12.4 65.5 14.8 24.3 32.7 5.9 6.7 29.6 55.6 22.7 22.8 9.3 7.3 15.7 27.6 22.8 5.4 34.9 8.9 20.1 43.5 19.6 23.2 14.5 52.9 33.3 62.5 19.7 7.5 21.5 38.5 36.6 6.9 21.5 22.2 48.8 30.2 25.8 27.0 10.6 41.9 15.7 17.8 25.0 31.8 37.7 28.5 38.9 29.8 27.6 28.4 17.3 47.5 27.6 52.3 43.7 26.9 57.6 25.9 45.4 38.9 29.5 12.0 25.9 26.9 22.2 71.7 74.7 25.8 39.0 91.2 44.1 66.7 36.7 38.4 19.2 39.8 34.7 45.0 19.4 25.8 15.6 17.6 59.0 31.3 31.3 33.2 41.2 39.3 50.0 39.5 28.9 50.1 28.4 37.4 41.0 21.9 45.0 63.7 48.4 10.9 21.2 28.9 66.1 56.0 38.2 31.0 36.7 38.2 50.1 24.5 14.8 15.0 34.6 10.8 14.0 12.3 12.6 19.1 18.5 9.8 11.2 17.2 15.0 39.0 8.6 19.4 20.7 5.5 7.1 7.9 10.2 5.9 6.7 9.3 7.3 8.9 7.5 6.9 10.6 49.7 80.1 57.7 23.2 46.4 120.4 92.4 78.6 113.8 44.1 49.3 35.6 69.1 51.5 81.5 25.8 56.3 43.0 74.6 338.1 25.4 51.0 271.5 130.1 85.5 44.1 62.8 259.8 35.5 52.7 64.6 48.8 93.8 267.2 63.3 40.0 29.6 88.5 41.1 28.6 34.2 119.9 50.8 59.9 51.2 305.8 22.4 85.7 42.7 15.9 80.6 18.3 53.5 34.2 49.5 148.4 210.7 30.1 63.4 118.5 199.5 52.5 72.3 46.4 6.6 43.9 51.6 28.4 10.1 164.2 143.6 88.4 57.3 71.1 77.2 244.4 RIT2 "RIBA, RIN" ENSG00000152214 "Ras like without CAAX 2" Q99578 18 42743227-43115691 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 25.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 225.8;Oligodendrocyte precursor cells: 202.5" "Cancer enriched" "Detected in single" 49 "glioma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA072174, HPA072526" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Golgi apparatus, Cytosol" "HPA072174: AB_2732195, HPA072526: " "unprognostic (1.37e-2)" "unprognostic (4.15e-1)" "unprognostic (2.14e-1)" 0.0 1.9 9.3 0.1 10.6 0.0 0.0 25.9 16.8 0.1 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 13.3 0.0 0.0 0.0 0.0 12.8 9.2 0.0 0.0 0.0 0.5 0.0 17.4 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 8.9 0.0 0.0 0.2 11.6 0.0 0.0 0.0 0.0 0.0 0.2 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 10.6 25.9 16.8 8.8 13.3 12.8 9.2 17.4 8.9 11.6 8.8 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 225.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 42.5 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 3.7 0.0 1.0 0.0 202.5 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 1.4 0.2 0.0 0.0 2.1 0.0 0.5 0.0 0.0 RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "retina: 265.6" "Cell type enriched" "Detected in some" 34 "Muller glia cells: 3148.2" "Group enriched" "Detected in some" 30 "glioma: 3.7;melanoma: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 53 "SK-MEL-30: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Nucleoplasm, Centrosome" "HPA042051: AB_2732495, HPA044083: AB_2678802" "unprognostic (3.19e-2)" "unprognostic (2.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-3)" "unprognostic (5.21e-2)" "unprognostic (3.17e-1)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.13e-1)" "unprognostic (8.42e-2)" 0.0 0.2 14.9 0.1 16.9 0.1 0.0 15.0 20.8 0.0 16.7 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.0 15.7 14.5 0.0 0.0 0.0 0.0 14.5 14.2 0.0 0.0 0.0 2.6 0.0 14.3 0.0 0.1 265.6 0.0 0.0 0.1 0.0 0.4 0.1 14.0 0.0 0.2 0.9 14.9 0.0 0.0 0.1 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.9 16.9 15.0 20.8 15.7 14.5 14.5 14.2 14.3 14.0 14.9 14.9 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.3 0.0 0.0 0.0 39.6 4.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 2.0 3148.2 0.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 20.0 0.0 0.0 0.0 0.0 RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 42.5" "Group enriched" "Detected in many" 4 "Early spermatids: 270.4;Late spermatids: 163.5;Theca cells: 77.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: AB_2674292, HPA034706: AB_10696362" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.76e-1)" "unprognostic (3.06e-2)" "prognostic favorable (2.63e-4)" "unprognostic (7.85e-2)" "unprognostic (9.96e-2)" "unprognostic (7.50e-2)" "unprognostic (1.94e-1)" "unprognostic (2.88e-2)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "unprognostic (4.34e-3)" "unprognostic (3.34e-1)" 4.6 42.5 3.8 4.1 3.5 3.4 5.3 4.8 4.5 7.7 2.9 12.4 8.4 5.1 9.2 3.4 3.9 6.2 4.4 4.1 2.6 7.8 29.2 11.3 4.6 3.9 2.6 2.8 4.1 3.2 3.0 3.9 2.6 7.2 10.6 4.2 3.7 12.8 5.1 2.9 13.9 5.8 3.0 20.0 4.4 21.7 3.6 5.9 5.4 3.2 2.9 4.3 3.5 3.7 3.3 4.7 2.6 1.8 10.4 11.4 1.5 7.0 9.3 3.6 3.2 1.1 10.9 2.2 2.8 9.9 2.2 3.5 0.8 5.1 4.9 5.0 3.0 3.6 1.6 3.1 5.3 0.0 3.8 16.2 4.6 4.5 0.7 5.4 2.0 1.8 4.4 2.1 6.8 1.3 0.9 4.5 5.1 6.5 3.8 0.0 0.8 0.6 9.0 2.7 2.1 7.5 5.7 0.7 7.3 2.2 1.1 5.9 3.8 4.4 5.1 2.5 2.6 3.8 7.7 4.6 5.4 1.1 4.6 0.0 2.8 0.7 2.0 4.6 3.1 4.1 1.0 1.3 1.8 2.3 1.0 2.2 2.7 3.7 3.5 3.4 0.1 1.4 3.8 3.5 4.8 4.5 4.1 2.6 3.9 2.6 2.6 3.0 3.6 3.7 3.4 28.9 29.6 25.1 6.5 2.4 6.8 16.3 8.6 3.5 1.9 4.2 5.3 11.5 20.0 5.5 2.1 2.1 6.0 20.9 7.9 5.4 270.4 3.7 11.8 4.6 4.8 3.0 33.8 3.8 1.0 9.2 2.6 3.1 15.8 13.1 5.3 15.5 4.7 5.0 24.5 11.4 6.1 6.3 1.7 163.5 9.3 4.8 5.4 19.7 4.4 4.7 6.2 39.2 7.1 2.5 6.1 6.0 1.8 2.2 29.6 6.7 10.2 2.6 6.6 6.4 5.1 9.4 4.8 1.7 2.4 0.8 3.9 77.6 15.2 2.3 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: AB_10965850" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (9.72e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (6.54e-2)" "unprognostic (1.85e-2)" "unprognostic (1.90e-1)" "prognostic favorable (2.72e-6)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" 7.2 9.5 8.8 6.6 8.7 5.8 11.3 8.5 9.2 9.8 9.7 8.1 15.9 8.4 20.0 7.4 11.6 7.8 10.0 8.8 9.0 16.4 11.5 7.6 8.1 8.8 9.1 11.2 10.9 24.3 9.5 11.1 8.8 10.6 10.3 15.7 15.1 13.6 17.2 8.3 13.9 11.8 9.0 6.7 9.2 8.7 9.1 7.7 12.9 14.9 10.4 9.1 7.1 8.7 10.9 22.7 20.5 14.6 19.1 15.2 13.8 16.7 17.7 25.4 26.9 46.0 20.9 9.2 14.9 18.5 26.7 22.1 22.7 21.2 26.7 13.8 13.1 14.0 21.5 21.9 14.3 12.8 11.5 14.8 17.9 28.7 18.2 27.9 46.7 13.5 23.2 8.6 22.7 23.5 9.0 14.1 13.7 43.4 21.9 11.0 44.5 7.9 28.3 18.4 13.7 14.6 22.9 20.4 30.4 20.6 22.5 9.5 32.8 19.0 17.2 11.8 14.6 9.6 10.2 9.4 16.5 8.3 17.1 4.4 2.2 2.2 3.0 2.9 3.5 3.2 2.3 2.4 2.3 1.3 2.7 2.9 1.2 3.2 2.1 3.7 2.1 2.9 8.8 8.7 8.5 9.2 8.8 9.0 8.8 9.1 8.8 9.0 9.1 8.7 9.6 6.4 9.6 12.7 9.4 8.8 11.2 22.8 10.2 16.1 12.1 10.9 9.7 12.8 13.3 20.2 20.9 32.0 17.9 15.2 7.9 26.0 6.3 8.9 10.3 6.5 9.6 13.0 19.3 32.3 26.5 11.8 9.2 10.9 7.0 11.6 8.9 14.4 14.2 10.1 16.9 13.2 26.4 6.6 12.9 3.0 13.1 7.6 10.6 15.0 15.0 19.0 10.3 18.1 19.0 29.0 11.0 12.4 17.1 10.3 31.0 20.9 10.3 21.1 19.7 10.0 14.2 25.1 19.6 6.4 5.8 31.1 10.0 13.4 9.4 9.9 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 591.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 462.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 48.2 41.2 58.1 40.4 95.2 19.9 53.9 88.1 91.5 33.6 63.7 35.0 28.9 33.3 57.2 32.6 30.2 40.6 34.4 55.0 77.3 67.9 73.8 64.1 38.0 101.8 83.9 35.6 36.1 52.3 18.3 64.1 100.8 46.6 37.1 40.4 75.5 39.3 36.5 32.5 30.5 36.9 85.6 53.0 34.3 25.2 75.9 32.0 64.0 42.6 33.2 42.3 28.9 131.0 60.6 39.4 24.4 29.0 92.2 55.2 40.3 32.2 86.2 32.3 47.4 33.4 84.4 26.6 48.7 42.0 58.7 58.0 37.5 41.5 42.9 34.1 24.6 35.8 17.3 31.2 61.5 35.0 41.8 59.9 73.1 26.5 71.8 37.3 37.0 24.9 10.1 49.7 28.0 34.5 26.2 18.8 16.8 58.6 29.1 19.0 26.7 108.5 54.2 29.6 12.6 37.6 28.5 39.9 110.3 19.2 79.2 34.0 37.8 40.8 16.5 45.6 23.4 89.9 61.9 51.5 35.9 30.1 23.6 98.2 130.1 106.5 37.4 153.8 48.8 51.9 41.5 44.8 93.1 48.4 38.0 42.4 462.3 46.3 207.8 68.3 48.7 104.5 58.1 95.2 88.1 91.5 55.0 77.3 101.8 83.9 100.8 85.6 75.9 131.0 100.9 109.0 72.3 78.7 55.3 73.5 68.2 84.3 74.0 44.5 54.5 51.1 27.3 48.6 68.1 47.8 29.2 101.2 61.9 30.2 43.0 63.0 2.5 32.5 34.5 69.4 20.3 32.4 122.1 70.6 83.5 84.8 31.6 39.7 60.8 14.6 80.3 53.7 201.2 21.9 98.8 27.7 67.1 183.9 173.7 6.7 76.1 177.6 103.2 92.8 93.5 98.5 38.1 115.6 591.2 58.7 33.6 88.0 62.4 71.9 38.5 71.5 40.4 37.2 92.1 76.3 55.5 23.6 32.5 52.3 72.5 52.5 49.8 38.2 27.7 55.8 RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" 27.4 39.3 13.7 39.4 15.9 20.4 28.2 16.2 16.1 24.7 18.6 26.4 12.2 21.0 30.9 53.1 16.9 48.3 18.8 15.6 19.8 19.5 15.3 73.6 38.7 11.1 13.1 29.0 12.3 47.7 19.4 52.4 11.6 25.9 29.3 33.8 25.6 32.7 9.0 22.3 16.6 27.4 14.3 29.2 26.7 12.1 20.3 26.5 33.8 13.7 48.4 68.1 24.4 14.7 65.5 63.5 95.2 115.1 98.5 43.6 18.6 51.3 88.9 46.3 74.6 22.2 52.9 22.4 89.7 45.3 87.9 83.1 75.9 67.3 80.9 92.7 27.2 47.2 68.5 18.4 42.1 31.4 43.2 27.0 118.8 43.2 63.0 64.7 46.2 53.6 47.7 83.6 44.1 1.9 36.1 9.8 41.3 20.5 32.0 47.3 41.6 44.8 61.4 22.3 34.5 63.9 51.8 54.7 86.5 64.7 38.5 28.4 49.7 51.6 47.0 41.9 92.1 18.4 27.6 20.6 60.3 38.4 113.1 3.5 2.5 16.0 3.0 2.6 3.5 11.4 4.4 3.6 1.9 5.1 5.8 4.0 9.5 2.3 2.3 2.7 6.3 1.3 13.7 15.9 16.2 16.1 15.6 19.8 11.1 13.1 11.6 14.3 20.3 14.7 34.1 112.2 244.1 25.1 62.9 122.7 102.0 90.0 73.4 106.7 97.2 77.3 12.7 65.8 114.0 36.8 58.4 2.8 55.1 98.4 19.6 75.0 28.9 27.5 37.1 75.7 54.1 67.5 89.2 114.4 24.3 45.7 52.0 36.7 69.1 30.2 127.8 19.5 45.5 114.4 74.2 41.8 32.6 115.0 240.8 39.5 46.3 69.4 65.8 52.5 153.9 56.1 47.4 40.2 38.9 108.6 53.7 51.9 38.1 123.8 16.9 10.6 65.6 53.4 46.0 25.4 46.5 19.2 34.8 81.9 99.4 10.9 69.3 19.0 72.0 163.1 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266682-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favorable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favorable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 52.9 37.0 49.5 32.4 56.0 10.6 42.7 79.4 61.2 48.1 36.2 40.5 21.9 57.4 60.8 25.3 42.4 38.6 46.9 50.7 51.6 37.1 31.8 38.7 35.1 53.2 52.1 49.5 23.3 40.0 33.3 51.8 56.8 31.7 30.9 48.1 31.2 34.5 114.9 29.5 31.1 45.9 55.2 47.1 29.9 31.3 52.5 24.3 47.1 91.5 33.3 36.9 34.3 61.5 13.2 16.2 60.3 53.6 54.7 54.3 22.2 43.5 69.0 22.8 32.4 21.3 19.3 23.6 30.3 35.7 36.2 16.4 18.1 20.4 32.9 27.6 16.0 30.3 21.8 30.0 54.0 18.0 20.6 47.6 42.1 26.1 51.1 52.5 40.6 23.2 33.0 22.5 50.7 25.2 17.9 32.0 22.1 8.1 17.1 22.6 15.7 12.1 32.4 14.3 36.0 36.6 17.1 23.6 27.7 35.5 16.1 60.8 48.3 39.7 13.1 41.8 31.7 32.3 22.0 15.6 30.5 31.0 38.5 27.5 30.0 26.6 14.3 32.4 14.7 17.4 12.2 16.3 22.8 17.9 11.0 15.5 37.0 19.8 40.1 11.7 15.0 16.1 49.5 56.0 79.4 61.2 50.7 51.6 53.2 52.1 56.8 55.2 52.5 61.5 24.6 35.3 29.3 35.6 23.7 17.7 14.3 15.1 18.8 34.7 16.9 14.7 38.9 31.5 16.7 9.2 4.2 29.0 14.7 13.5 41.1 28.0 52.5 15.7 29.5 30.5 20.4 12.8 53.5 15.8 27.2 50.6 7.1 11.5 22.2 28.1 31.4 30.5 26.3 30.3 54.5 12.1 38.7 68.4 24.6 45.4 69.6 29.9 46.2 42.2 31.1 41.1 28.8 56.3 76.5 18.0 17.0 66.5 9.3 26.3 15.7 51.7 23.9 20.9 32.9 36.2 31.9 41.7 24.9 15.0 20.0 38.4 20.8 36.0 10.9 25.9 RNF151 ENSG00000179580 "Ring finger protein 151" Q2KHN1 16 1966823-1968975 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 411 "testis: 190.2" "Group enriched" "Detected in some" 137 "Early spermatids: 2202.5;Late spermatids: 1521.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055054 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Cytosol "Nuclear speckles, Vesicles" "HPA055054: " "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-2)" "unprognostic (4.01e-3)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.20e-1)" "unprognostic (4.39e-3)" "unprognostic (4.63e-1)" "unprognostic (1.98e-4)" "unprognostic (1.46e-1)" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (2.43e-2)" 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2202.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1521.4 9.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.2 0.1 13.5 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "dendritic cells: 132.3;NK-cells: 111.2;T-cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" 22.7 18.4 16.1 28.8 16.2 91.2 16.0 14.4 24.5 18.3 13.9 18.3 14.1 16.6 3.2 11.8 20.0 14.0 21.3 15.5 15.0 20.7 23.4 48.3 40.4 19.4 16.8 17.8 19.5 5.4 17.6 8.2 17.6 19.7 4.9 3.4 14.8 5.8 21.3 11.8 37.2 6.3 16.9 101.6 17.8 12.8 20.9 18.0 18.8 8.2 21.1 18.1 14.4 20.0 10.3 15.9 12.5 18.4 5.8 5.0 23.3 10.3 6.5 11.8 5.3 11.1 6.4 12.4 13.0 6.0 6.8 11.1 7.2 6.8 4.7 6.4 21.7 16.7 12.4 18.7 15.9 16.7 20.4 6.0 6.4 9.4 8.2 6.9 12.4 20.6 28.6 8.8 5.0 20.3 38.9 108.0 20.3 4.4 21.5 36.3 7.8 32.2 5.3 4.5 11.8 12.3 23.9 4.8 12.1 5.9 13.4 53.3 18.6 8.7 13.4 13.5 12.5 19.9 13.5 31.6 7.8 62.8 12.4 7.0 25.6 61.3 31.6 19.1 27.7 4.2 19.3 27.6 23.8 3.9 15.7 22.9 40.4 11.3 22.7 14.8 21.8 21.6 16.1 16.2 14.4 24.5 15.5 15.0 19.4 16.8 17.6 16.9 20.9 20.0 15.2 9.6 3.6 7.8 23.5 4.8 4.6 2.4 6.2 10.1 6.0 7.1 2.8 4.3 3.1 7.3 6.2 8.8 132.3 2.3 9.8 6.5 1.4 5.2 7.4 11.0 4.9 13.7 6.5 9.2 9.6 8.8 8.2 4.9 21.0 12.3 8.6 4.8 38.8 8.4 4.8 3.1 2.0 46.7 32.4 2.5 9.3 52.4 10.6 15.0 41.5 11.7 111.2 3.5 4.5 5.5 1.0 7.9 55.1 4.5 1.8 7.0 4.7 9.6 6.6 8.9 10.0 9.1 9.9 4.8 5.8 3.7 73.1 12.2 3.7 1.9 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748849-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038505, HPA046138, HPA047952" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Nucleoli, Nucleoli rim, Cytosol" "HPA038505: , HPA046138: AB_2679553, HPA047952: " "unprognostic (1.71e-1)" "unprognostic (4.18e-2)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (3.86e-2)" "unprognostic (3.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-1)" "unprognostic (6.47e-2)" "prognostic unfavorable (8.04e-4)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.23e-1)" "unprognostic (2.34e-1)" "unprognostic (9.55e-3)" "unprognostic (1.21e-1)" 4.2 2.8 3.8 6.7 6.2 14.4 5.6 6.2 4.4 5.5 5.4 4.4 4.0 7.6 4.2 10.1 5.6 4.8 3.2 4.0 4.4 4.6 5.0 5.9 6.3 5.4 5.0 7.6 4.4 5.6 2.1 4.7 5.4 5.2 5.3 6.1 4.5 4.3 6.8 5.5 4.4 7.6 4.4 7.3 4.6 2.9 4.6 7.7 5.8 5.8 6.7 5.2 5.4 9.2 10.2 7.7 9.1 9.0 5.8 7.7 3.7 7.9 7.4 8.6 7.4 13.0 7.5 18.2 7.9 9.5 5.8 9.6 12.4 9.3 11.2 9.1 8.0 12.6 15.3 5.1 6.6 6.8 10.1 7.1 7.2 9.8 22.1 9.6 14.0 12.2 11.4 14.1 8.7 8.6 11.6 12.0 3.6 12.9 5.0 10.7 21.7 9.9 5.5 10.6 4.1 7.4 10.6 8.0 16.6 7.3 9.9 8.6 9.4 14.2 11.8 9.0 7.1 10.2 5.8 21.1 2.8 7.3 8.4 1.2 0.5 0.4 0.4 0.3 0.3 0.0 0.4 0.2 0.2 0.1 0.3 0.2 1.4 0.3 0.3 0.2 0.3 0.2 3.8 6.2 6.2 4.4 4.0 4.4 5.4 5.0 5.4 4.4 4.6 9.2 18.8 9.6 11.4 51.6 18.4 19.9 30.6 7.1 20.5 58.2 12.6 9.8 3.0 17.2 8.3 3.7 52.1 5.5 24.6 9.8 5.9 10.2 2.8 30.5 26.7 17.2 12.0 18.3 40.8 11.1 6.4 16.0 14.8 30.1 7.0 24.4 10.8 12.3 8.5 37.0 43.2 8.7 2.0 15.6 19.9 3.1 7.5 16.6 10.6 25.3 12.6 22.9 26.8 42.7 68.7 10.1 6.8 10.5 18.5 49.7 6.3 12.1 8.9 33.7 26.3 31.9 18.7 9.4 11.7 16.4 18.6 8.1 22.2 14.0 10.4 42.2 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.7;choroid plexus: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 85.2" "Cancer enhanced" "Detected in many" "glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 81.3;RPTEC TERT1: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.1 0.1 12.2 0.1 13.3 8.4 0.6 22.5 17.7 0.8 12.7 0.2 0.2 0.6 1.1 0.3 1.2 0.2 0.3 17.6 12.2 1.1 0.0 3.3 0.2 16.9 17.7 0.3 1.7 5.8 1.8 1.3 16.5 0.4 0.1 8.8 1.3 2.1 0.2 0.4 0.3 0.3 14.2 0.2 0.2 3.7 24.7 1.5 1.3 0.1 0.0 0.3 0.4 12.2 0.2 6.5 12.0 0.0 4.1 5.0 0.7 6.3 8.6 17.0 16.4 0.3 0.1 0.0 0.1 6.8 18.5 0.0 14.3 0.1 30.9 0.0 4.7 0.4 81.3 0.0 0.0 0.1 0.0 2.8 0.0 26.3 0.2 19.5 0.3 3.5 0.5 0.0 11.9 0.2 0.1 2.2 6.9 0.1 23.9 3.8 2.9 1.0 67.3 0.0 14.2 13.7 0.6 0.0 24.8 4.4 0.0 2.4 6.5 20.7 4.4 0.2 14.3 0.0 0.0 0.0 14.1 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 13.3 22.5 17.7 17.6 12.2 16.9 17.7 16.5 14.2 24.7 12.2 0.2 0.0 0.0 85.2 0.1 0.3 0.1 0.0 0.0 19.3 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 0.4 0.1 0.2 0.0 9.7 8.6 0.0 0.1 0.4 0.0 0.1 0.0 5.4 0.0 0.1 0.1 15.2 1.5 0.1 0.0 0.0 0.3 1.4 0.3 0.0 0.0 5.6 0.0 14.7 0.0 2.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 1.1 0.1 1.3 6.6 0.0 1.3 5.7 3.2 0.0 0.0 0.3 0.3 0.0 0.1 0.1 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663892-218672002 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Actin filaments" "HPA036420: AB_2675114, HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 10.9 11.4 18.5 8.9 18.6 7.3 10.9 18.3 21.0 12.2 17.1 12.0 6.2 12.7 15.8 11.7 12.4 10.8 13.9 18.6 19.7 10.4 11.1 10.4 14.5 18.4 18.4 14.5 11.5 15.1 11.4 11.4 19.0 11.8 8.2 7.0 11.0 13.9 15.0 14.5 7.9 13.6 18.5 10.3 9.4 14.3 19.2 15.1 14.1 17.1 11.9 14.0 9.7 19.0 18.8 20.4 22.1 24.6 27.6 17.5 20.4 27.3 43.5 58.0 53.6 32.4 13.2 11.6 17.6 42.3 35.2 19.5 22.1 33.9 31.0 16.4 27.3 22.7 21.3 34.6 33.6 19.3 20.6 33.9 30.9 55.5 44.7 21.4 31.0 40.9 27.4 24.3 41.1 45.3 20.6 20.4 32.9 16.2 23.4 23.2 15.5 15.9 36.3 21.8 19.5 23.8 18.1 17.2 28.4 21.9 20.6 25.6 26.6 40.2 20.5 19.2 31.1 23.7 13.7 23.5 33.4 19.1 25.7 58.6 21.5 32.6 26.0 21.3 24.8 25.7 25.7 27.2 17.1 30.4 29.0 23.2 17.1 30.5 25.2 15.0 25.9 24.8 18.5 18.6 18.3 21.0 18.6 19.7 18.4 18.4 19.0 18.5 19.2 19.0 4.2 0.0 0.5 5.2 7.8 6.2 4.8 16.3 6.8 7.7 3.4 3.7 4.0 10.0 8.9 1.8 8.4 12.3 4.5 7.4 15.6 12.3 16.8 6.3 8.1 7.6 1.2 2.1 6.2 12.9 9.7 7.5 9.7 4.8 7.0 5.9 8.9 7.1 13.2 5.0 5.8 5.5 8.2 5.0 4.0 5.3 7.2 5.5 8.8 2.8 8.9 7.9 9.2 3.5 4.9 12.7 9.6 12.8 8.5 3.8 7.2 14.8 8.2 5.0 26.3 5.6 9.2 19.3 12.8 5.9 6.8 10.0 8.0 8.5 6.1 3.6 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" 14.3 15.8 12.7 11.5 12.6 22.0 13.3 13.7 15.1 15.4 10.6 19.2 14.5 23.5 10.3 20.9 16.6 10.5 13.2 12.7 12.5 13.6 23.6 12.4 11.8 15.2 13.1 17.1 13.8 18.5 10.4 14.2 15.5 14.8 12.6 8.4 14.9 18.6 8.5 15.7 17.0 19.0 12.7 14.6 19.1 15.1 14.7 13.3 13.2 7.1 12.8 18.9 14.2 13.1 43.8 47.4 43.4 51.4 41.8 32.8 46.0 46.3 49.7 52.8 41.5 80.6 88.9 38.3 62.5 55.5 80.1 77.2 61.9 69.8 33.0 46.0 34.2 101.0 21.8 67.3 31.9 42.8 40.4 34.3 35.2 66.1 59.0 34.7 40.8 58.1 50.0 58.4 36.9 94.9 39.5 44.3 43.5 50.2 59.8 40.5 44.5 30.4 32.7 31.1 30.8 29.9 37.4 46.8 12.5 41.4 106.1 35.4 27.0 63.5 41.8 33.7 43.0 14.0 24.6 0.4 21.3 71.0 50.6 9.5 21.6 5.6 20.8 19.2 13.4 11.1 15.7 18.4 19.0 16.7 17.5 15.5 1.5 14.0 20.2 11.0 8.7 24.9 12.7 12.6 13.7 15.1 12.7 12.5 15.2 13.1 15.5 12.7 14.7 13.1 5.1 3.2 9.4 1.0 9.1 6.9 13.3 15.4 12.5 9.2 10.9 9.8 0.8 22.8 11.1 11.0 2.1 44.0 6.2 9.3 5.9 20.8 6.6 5.9 7.9 8.6 13.8 18.5 3.2 17.0 66.0 11.5 9.2 5.9 7.6 16.9 11.4 23.4 21.5 5.0 2.9 13.0 8.2 14.8 5.9 8.6 14.0 6.6 1.8 1.0 11.6 11.6 15.5 4.5 2.7 14.1 7.5 17.7 4.3 14.2 15.6 12.5 4.8 9.4 6.6 6.5 10.6 19.9 10.5 14.3 8.5 24.4 8.3 8.8 18.6 9.8 RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;skin 1: 63.3;vagina: 21.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 79.9;Basal respiratory cells: 96.2;Club cells: 55.7;Prostatic glandular cells: 57.2;Urothelial cells: 233.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.5;U-266/84: 3.6" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 9.0;cerebral cortex: 8.0;hippocampal formation: 4.4" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: AB_2679938" "unprognostic (1.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.53e-2)" "unprognostic (5.72e-3)" "unprognostic (3.08e-2)" "unprognostic (4.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.22e-2)" "unprognostic (1.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.61e-2)" "unprognostic (2.06e-4)" "unprognostic (5.61e-2)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-2)" 1.1 0.8 0.0 0.0 0.1 0.0 8.6 0.1 0.3 16.8 0.0 0.6 0.2 0.6 0.0 24.5 1.4 0.1 0.3 0.1 0.1 0.4 0.2 1.9 0.0 0.2 0.0 1.3 1.7 0.1 1.4 0.0 0.2 7.2 0.0 0.5 15.8 0.1 0.4 63.3 0.5 0.0 0.0 0.2 8.3 1.6 0.1 0.0 0.4 0.0 0.4 3.9 21.6 0.1 1.2 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.2 1.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 0.9 0.3 0.2 0.0 0.4 0.0 0.5 0.0 4.5 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.8 3.6 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.3 3.2 2.7 0.0 0.0 17.8 79.9 96.2 42.1 0.5 23.7 28.6 0.3 7.2 55.7 0.0 0.0 0.0 0.8 1.8 0.0 6.4 0.6 3.6 2.4 1.1 0.0 0.0 0.0 3.3 0.0 1.2 17.3 20.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 14.2 0.0 2.1 0.0 1.2 0.4 3.6 0.0 0.6 0.0 0.0 0.0 0.0 24.2 2.2 1.2 0.0 57.2 0.1 0.0 13.0 0.4 0.0 0.0 3.0 0.1 0.4 11.3 23.9 0.7 0.6 0.0 0.9 233.1 RNF4 "RES4-26, SLX5, SNURF" ENSG00000063978 "Ring finger protein 4" P78317 4 2462220-2625320 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022047, HPA049356" Approved Supported "Nucleoplasm,Nuclear bodies,Microtubule ends" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Microtubule ends" "HPA022047: , HPA049356: AB_2680726" "unprognostic (8.38e-3)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (9.31e-3)" "unprognostic (9.03e-3)" "prognostic unfavorable (6.38e-4)" "unprognostic (1.34e-1)" "unprognostic (6.79e-2)" "unprognostic (2.58e-1)" "unprognostic (5.64e-2)" "unprognostic (1.93e-2)" "unprognostic (6.40e-2)" "unprognostic (4.70e-2)" "unprognostic (8.67e-2)" "unprognostic (1.54e-1)" 30.2 30.9 24.0 36.0 24.9 46.4 29.2 26.0 25.1 29.4 26.5 27.9 29.0 29.5 28.3 30.7 28.5 28.3 27.0 24.5 25.5 32.6 25.9 27.8 49.9 26.0 25.9 31.0 31.2 33.6 26.8 28.4 25.2 28.2 27.4 24.0 28.0 28.1 27.7 29.7 30.4 33.1 23.9 40.3 30.1 31.9 26.3 50.1 30.7 23.2 50.0 35.0 26.8 25.5 60.9 57.0 57.9 42.0 50.6 52.2 65.6 73.3 83.4 77.3 70.0 65.1 56.8 77.6 42.0 76.0 101.5 39.7 63.5 58.6 72.7 37.6 38.5 92.4 54.6 62.6 76.6 66.7 77.8 61.0 69.7 72.3 59.4 53.6 73.1 64.8 50.0 103.2 80.4 43.5 105.0 92.5 89.8 52.3 70.9 76.6 55.3 40.8 52.6 74.5 54.3 51.0 50.5 40.4 52.1 62.9 63.1 50.6 60.0 65.8 32.0 64.2 115.4 131.3 189.5 82.6 64.6 72.7 69.5 44.7 70.0 104.6 97.7 95.4 97.2 85.0 82.2 97.0 84.1 59.1 78.8 80.3 77.2 99.2 103.8 56.5 98.8 128.6 24.0 24.9 26.0 25.1 24.5 25.5 26.0 25.9 25.2 23.9 26.3 25.5 31.1 22.4 17.5 17.0 36.0 27.5 18.4 17.7 31.3 11.9 24.0 16.0 20.7 12.8 21.3 22.0 16.7 21.3 45.9 16.5 21.5 22.2 14.0 17.0 22.8 21.7 12.1 15.4 15.9 23.3 35.0 19.5 23.0 23.9 14.5 22.7 16.4 20.4 19.7 13.5 17.8 16.8 8.2 34.0 28.5 22.4 17.1 27.8 7.2 18.7 35.1 11.5 43.3 13.0 16.3 29.8 14.3 20.7 47.8 27.1 23.1 21.2 17.6 17.7 26.3 18.2 22.0 31.2 48.6 27.0 32.1 21.8 39.7 16.4 18.9 32.9 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202179-56221933 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 32.2 24.6 22.5 18.0 23.3 19.6 21.4 15.7 23.8 21.2 13.0 23.8 12.4 22.3 13.2 23.1 24.3 25.5 32.7 24.6 24.8 19.7 15.1 23.8 23.4 16.8 19.1 22.9 23.0 27.4 22.8 21.3 21.2 33.9 19.0 23.8 15.0 20.7 34.0 15.0 16.1 28.5 15.3 20.6 17.0 15.9 23.5 26.5 28.6 40.8 25.1 28.2 17.0 19.2 21.6 32.6 34.7 55.2 71.0 51.3 25.8 70.8 69.5 62.2 50.2 40.0 27.6 41.6 36.7 60.2 20.6 24.3 47.4 34.1 44.9 43.8 25.7 55.8 22.3 23.2 148.3 61.6 58.3 66.0 78.6 52.0 91.0 81.7 61.3 34.5 40.4 41.3 35.1 34.9 35.6 27.6 41.9 21.6 37.8 38.2 24.9 25.3 33.3 31.3 62.9 38.1 61.9 35.0 55.4 34.3 49.2 71.3 37.3 31.3 32.9 40.6 27.8 29.6 36.6 37.5 37.2 36.4 38.0 59.1 27.2 99.9 27.6 26.7 24.9 50.3 23.0 24.3 30.6 55.1 23.4 24.0 36.2 33.1 28.3 23.7 29.4 31.0 22.5 23.3 15.7 23.8 24.6 24.8 16.8 19.1 21.2 15.3 23.5 19.2 18.9 44.8 22.6 11.1 42.2 12.0 19.9 8.6 19.9 30.7 22.2 21.1 24.6 24.3 18.8 16.5 22.9 15.2 17.0 10.2 17.6 15.3 92.8 13.9 14.2 20.7 20.4 11.1 15.0 21.3 18.5 22.7 9.7 14.2 25.9 16.8 30.0 16.7 19.3 28.6 15.7 13.9 8.2 34.9 22.7 58.0 23.0 25.0 7.2 9.4 33.5 26.2 15.5 14.6 12.3 20.8 20.3 25.9 14.6 33.5 12.3 19.6 18.0 18.3 26.3 23.2 27.4 10.4 14.2 14.4 16.6 16.8 16.6 17.1 14.3 23.1 ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3438.7;Inhibitory neurons: 4706.0" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 29.8;HEL: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" 0.7 2.4 10.1 0.5 13.6 0.0 0.6 0.0 14.2 2.4 0.0 0.8 0.5 2.1 0.4 4.8 0.1 2.3 0.6 10.4 1.7 1.8 1.2 10.0 1.5 14.8 13.1 7.0 1.6 2.8 1.5 5.2 14.3 1.2 0.4 15.4 1.6 5.7 0.1 2.3 0.7 1.4 16.7 2.9 0.7 3.7 4.9 9.3 0.1 0.4 2.2 1.2 1.7 8.1 0.0 0.0 2.2 0.0 7.5 8.1 0.1 0.3 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 9.8 83.9 1.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 5.1 9.1 0.0 0.0 1.1 5.1 12.2 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 13.6 0.0 14.2 10.4 1.7 14.8 13.1 14.3 16.7 4.9 8.1 0.7 0.0 0.5 164.6 0.0 1.8 2.0 0.4 19.4 30.8 0.2 1.0 2.4 1.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 1.0 1.7 1.1 0.0 0.0 3438.7 0.0 0.1 10.6 0.0 3.2 0.0 2.3 3.3 0.7 0.1 52.2 4706.0 3.0 0.0 0.0 2.8 3.4 3.1 0.1 0.0 54.4 0.0 2.0 0.0 63.3 52.4 0.2 0.0 6.0 0.0 0.8 0.3 0.1 0.1 5.6 0.0 0.1 0.9 2.9 1.1 15.7 1.1 0.1 0.2 40.5 0.5 0.2 RP2 "NM23-H10, NME10, TBCCD2" ENSG00000102218 "RP2 activator of ARL3 GTPase" O75695 X 46837043-46882358 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 62.8;Langerhans cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000234, HPA000909" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA000234: AB_1079831, HPA000909: AB_2666140" "unprognostic (2.26e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-2)" "unprognostic (2.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.97e-4)" "unprognostic (2.58e-2)" "unprognostic (9.76e-3)" "unprognostic (3.10e-2)" "unprognostic (3.79e-3)" "unprognostic (9.75e-2)" "unprognostic (6.15e-3)" "unprognostic (2.96e-2)" "unprognostic (9.66e-2)" "unprognostic (1.61e-1)" "unprognostic (4.28e-3)" 10.9 8.9 1.9 15.6 2.3 49.5 7.2 2.6 2.3 7.9 3.6 10.1 10.6 6.9 4.0 12.9 6.8 12.7 4.8 1.7 2.7 6.7 13.2 11.8 12.9 3.3 2.8 6.5 4.6 7.4 1.7 25.2 3.5 6.7 10.5 4.2 4.4 5.3 2.0 5.3 11.0 9.0 3.5 13.2 8.1 4.0 2.3 9.8 6.1 3.6 11.2 10.4 4.2 4.6 21.8 10.3 20.4 11.0 15.7 19.4 48.0 27.4 21.5 23.8 23.9 44.6 18.2 25.8 10.7 29.3 20.1 14.0 19.8 20.0 32.1 11.5 11.5 13.9 11.7 10.7 17.9 29.2 46.4 15.1 13.0 18.8 10.1 13.3 30.5 11.4 6.2 13.1 27.0 1.9 18.1 26.8 12.5 14.8 19.5 22.9 27.9 13.8 15.3 22.0 7.4 10.0 24.4 14.9 12.4 36.2 16.8 27.1 27.1 18.3 13.6 29.1 9.8 4.9 6.8 15.4 9.5 20.4 19.5 62.6 22.6 35.5 6.1 30.8 5.0 10.3 4.9 5.3 22.6 9.6 6.0 5.7 43.5 7.6 36.3 7.6 6.1 12.2 1.9 2.3 2.6 2.3 1.7 2.7 3.3 2.8 3.5 3.5 2.3 4.6 9.6 9.6 7.4 3.9 18.9 15.8 3.2 6.1 15.4 3.1 7.8 6.1 1.7 7.2 5.1 9.2 2.1 23.2 12.0 28.6 0.0 4.7 2.8 15.8 14.5 8.6 3.6 10.3 3.1 5.3 6.4 10.3 12.8 14.9 12.0 4.0 12.5 20.1 24.3 0.0 4.0 9.4 2.0 62.8 72.9 1.7 5.6 44.7 21.4 6.5 36.6 3.6 6.2 12.1 5.9 11.6 13.4 5.7 13.2 8.2 9.8 3.6 14.5 5.5 6.6 7.7 10.5 7.8 4.6 36.4 14.9 38.2 11.4 4.7 10.5 13.6 RP9 PAP-1 ENSG00000164610 "RP9 pre-mRNA splicing factor" Q8TA86 7 33094797-33109404 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031523, HPA050778" Uncertain Enhanced Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Vesicles, Cytosol" "HPA031523: AB_10603235, HPA050778: AB_2681233" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (1.07e-2)" "unprognostic (1.82e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.22e-2)" "unprognostic (7.53e-2)" "unprognostic (7.03e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.65e-5)" "unprognostic (4.19e-2)" "unprognostic (2.63e-2)" "unprognostic (2.70e-1)" "unprognostic (1.61e-1)" 12.6 15.0 26.3 8.7 26.1 21.6 12.6 28.0 51.2 17.0 26.7 16.7 9.0 14.4 15.5 10.1 14.0 6.2 29.2 25.8 26.3 17.2 13.8 12.0 15.6 26.6 26.3 16.2 20.2 10.5 10.3 10.2 26.7 14.4 9.8 16.7 11.5 11.7 36.3 13.8 15.9 8.4 25.8 20.8 13.5 18.1 26.9 13.8 16.0 34.3 16.7 14.3 13.1 27.4 20.9 28.8 29.7 34.1 18.5 17.2 14.3 26.4 21.6 28.9 23.0 25.6 14.6 26.2 17.0 21.1 35.4 20.4 36.4 22.0 36.8 11.9 25.1 19.2 22.8 24.4 32.4 26.0 13.0 17.5 20.2 32.8 64.5 23.3 24.0 27.1 35.2 23.0 29.1 42.6 27.7 69.6 25.4 27.2 21.9 28.2 26.4 17.1 21.1 19.3 28.7 39.5 18.7 39.6 46.2 35.1 20.8 35.0 19.4 28.4 40.9 25.6 42.8 38.1 37.2 51.7 20.0 36.3 56.1 21.9 12.0 21.6 15.2 9.8 14.1 57.8 16.3 17.4 13.2 77.3 19.1 18.0 2.0 15.7 12.5 28.4 15.8 8.8 26.3 26.1 28.0 51.2 25.8 26.3 26.6 26.3 26.7 25.8 26.9 27.4 21.3 12.8 10.1 4.9 35.6 21.0 15.1 11.3 29.0 15.8 17.7 27.9 41.7 17.2 10.9 14.7 14.6 20.2 16.8 12.6 21.5 16.0 5.6 14.6 28.2 24.1 10.2 19.4 6.5 15.8 20.0 20.4 20.4 16.6 3.8 26.8 15.4 16.4 18.4 8.4 7.5 19.3 24.4 10.1 14.9 3.2 18.0 12.0 23.2 5.6 10.1 21.9 21.6 3.0 8.7 14.6 8.0 16.1 24.4 22.9 16.1 18.6 8.5 16.4 26.3 19.4 30.3 31.6 54.3 24.4 18.0 10.4 19.9 22.9 18.4 12.0 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 130000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (5.07e-2)" "unprognostic (8.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.42e-6)" "unprognostic (1.59e-3)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "unprognostic (5.84e-2)" 21.9 27.6 15.9 20.1 20.0 19.4 25.4 18.3 21.7 19.7 11.9 24.0 21.8 22.6 22.3 29.1 21.0 19.8 14.5 16.2 14.7 30.0 27.4 17.9 25.1 11.0 13.3 25.4 15.1 21.0 17.2 29.4 12.8 22.5 31.8 17.8 20.6 31.1 11.0 19.7 19.8 29.3 14.6 19.2 24.2 15.3 16.5 22.9 29.5 27.4 29.4 27.4 17.4 23.1 62.4 81.0 47.5 47.9 71.3 68.0 85.4 80.2 60.9 67.9 93.1 118.7 92.1 39.9 50.6 58.8 104.1 59.9 69.7 81.9 103.3 49.7 47.8 78.2 112.3 112.3 98.8 80.7 56.1 51.7 75.4 83.2 107.5 60.2 94.8 39.1 79.7 57.2 55.5 106.7 43.5 63.5 68.2 121.4 59.8 52.4 58.4 56.7 78.6 94.7 56.6 31.4 70.2 63.7 52.3 85.6 54.4 85.2 80.0 96.7 66.9 47.5 73.8 31.9 49.5 88.6 69.6 76.0 62.5 20.2 40.2 19.1 23.1 51.0 19.8 20.2 17.7 21.7 69.5 21.6 23.4 21.0 3.7 77.2 34.8 25.4 26.7 28.8 15.9 20.0 18.3 21.7 16.2 14.7 11.0 13.3 12.8 14.6 16.5 23.1 14.9 6.4 7.5 14.4 13.1 16.6 15.2 21.6 13.1 13.2 13.2 10.3 6.2 10.0 20.1 18.4 20.9 35.4 18.1 14.0 31.3 24.5 10.7 13.5 17.4 14.3 10.2 17.2 61.9 17.5 42.8 17.4 14.3 11.2 6.3 18.1 18.2 17.5 37.0 10.1 44.7 14.6 14.2 19.4 45.8 11.8 11.1 17.2 14.2 15.0 19.7 8.9 26.8 27.2 39.2 19.4 11.6 14.7 12.2 19.9 14.2 48.6 15.9 12.7 6.6 11.1 16.1 14.7 17.4 20.1 20.3 25.6 10.5 24.8 21.3 14.8 RPEL1 ENSG00000235376 "Ribulose-5-phosphate-3-epimerase like 1" Q2QD12 10 103245887-103248016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.1;Cone photoreceptor cells: 8.4;Ionocytes: 2.0;Rod photoreceptor cells: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (7.52e-2)" "unprognostic (1.69e-1)" "unprognostic (4.78e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.83e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.91e-2)" "unprognostic (6.59e-2)" "unprognostic (4.34e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (1.62e-1)" "unprognostic (6.72e-2)" "unprognostic (5.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.0 3.1 0.0 0.0 1.9 0.0 0.7 0.0 8.4 0.3 1.3 0.5 0.0 0.5 0.1 0.1 0.0 0.3 1.8 0.0 0.6 0.2 0.5 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.5 2.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.5 0.1 0.2 4.4 0.0 0.0 0.4 0.1 0.3 0.0 0.3 0.4 0.1 0.0 0.7 0.0 RPF2 "bA397G5.4, BXDC1, FLJ21087" ENSG00000197498 "Ribosome production factor 2 homolog" Q9H7B2 6 110982015-111028263 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2197: 234.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035475 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA035475: AB_10669861" "unprognostic (2.85e-3)" "unprognostic (2.19e-2)" "unprognostic (6.00e-2)" "unprognostic (2.90e-3)" "unprognostic (4.45e-1)" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.99e-1)" "unprognostic (8.43e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (2.07e-6)" "unprognostic (2.39e-2)" "unprognostic (2.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.86e-1)" 16.4 12.2 6.6 9.5 7.4 10.8 14.9 7.3 8.7 12.9 7.2 11.9 6.6 11.2 5.4 15.2 12.5 9.1 15.3 7.0 7.1 15.8 17.2 9.7 10.4 6.9 6.9 13.2 19.9 9.7 8.1 10.2 7.0 11.4 8.8 5.6 9.9 7.1 22.2 13.9 8.1 8.1 6.9 9.3 11.7 13.5 7.1 7.6 13.0 14.0 10.9 15.3 12.5 7.9 23.3 16.6 12.7 50.5 26.4 34.7 32.6 32.5 23.6 32.3 32.6 39.2 18.5 50.2 29.4 22.8 38.8 27.0 51.5 37.6 84.2 19.4 38.7 29.5 14.2 27.4 35.9 45.9 16.6 26.5 31.4 46.5 83.5 20.3 24.9 22.1 99.0 29.9 52.2 23.4 39.2 45.5 45.2 37.7 20.2 40.2 22.4 43.6 37.4 22.9 20.3 28.7 14.1 23.7 61.3 16.8 18.8 47.3 17.5 24.7 21.2 234.1 81.4 13.4 22.0 65.0 36.4 60.8 55.2 0.2 4.4 0.7 4.1 5.5 8.5 6.6 6.1 5.0 5.8 5.7 6.8 7.0 0.3 8.8 3.5 5.8 5.0 4.0 6.6 7.4 7.3 8.7 7.0 7.1 6.9 6.9 7.0 6.9 7.1 7.9 40.0 19.2 26.9 6.5 25.0 78.4 119.6 90.1 35.9 14.1 33.6 52.3 71.9 47.1 67.6 18.4 0.0 44.9 18.0 15.8 68.4 48.2 105.7 49.8 57.6 35.2 11.4 26.1 15.7 47.4 53.8 50.0 17.3 60.9 46.2 18.9 23.6 83.6 56.0 18.5 14.0 30.3 36.7 27.7 19.5 32.1 34.5 28.2 37.4 5.6 21.8 21.0 19.6 9.0 13.5 42.2 18.7 27.1 18.8 80.4 15.2 87.2 55.0 8.9 13.1 61.7 49.9 76.8 28.4 33.0 66.2 34.6 22.9 29.8 44.0 70.2 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 RPL10A "Csa-19, L10A, NEDD6" ENSG00000198755 "Ribosomal protein L10a" P62906 6 35468401-35470785 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053803 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 740000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA053803: AB_2682268" "unprognostic (5.47e-2)" "unprognostic (8.02e-2)" "unprognostic (1.45e-1)" "unprognostic (3.37e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (3.34e-2)" "unprognostic (4.74e-2)" "unprognostic (1.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.37e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (2.21e-2)" "unprognostic (1.40e-1)" "unprognostic (1.16e-1)" "unprognostic (9.72e-2)" 1323.4 939.9 613.7 824.8 622.4 2051.4 2092.0 591.3 764.2 1803.2 604.3 1445.1 776.4 1350.0 1255.9 1583.0 1911.2 720.6 845.6 594.7 625.1 957.2 840.9 835.2 1625.6 619.7 603.1 3180.4 1894.4 682.3 731.1 747.7 627.8 1322.3 1178.3 255.2 1271.7 1007.2 1411.5 2166.4 1075.0 1114.2 654.0 1063.9 1188.8 230.5 628.8 1585.0 1084.1 1009.5 1733.0 1434.0 1506.3 642.7 1205.5 1211.3 1349.6 1275.9 1967.9 3560.6 1522.8 1213.7 2475.5 1671.2 1320.9 1765.5 1126.2 3571.4 1089.8 1650.2 819.4 1036.0 1832.7 2764.1 1374.0 1249.1 1618.0 1375.9 1007.0 2501.0 2909.6 2031.3 1096.1 4179.2 3172.8 1225.0 4066.4 2689.3 2481.9 1760.1 1652.9 1712.2 1920.0 2112.5 2158.4 2452.2 1421.3 1879.5 1057.5 1681.9 1298.7 2801.6 2124.0 1949.5 945.6 1384.7 747.8 1688.0 3632.5 1076.1 1831.0 3628.9 1450.9 541.4 975.4 729.4 1559.5 1073.4 1889.4 2381.8 681.1 2322.7 992.7 215.5 1232.7 120.6 1478.3 1210.1 2629.7 3176.9 2436.2 1905.6 1990.0 2806.5 3252.5 2601.9 113.1 2069.4 1077.8 1875.3 2059.9 5496.8 613.7 622.4 591.3 764.2 594.7 625.1 619.7 603.1 627.8 654.0 628.8 642.7 973.2 535.2 1036.5 19.2 3101.2 5399.7 5910.9 3550.3 2636.7 221.4 4627.1 4144.2 270.8 1742.9 1828.0 597.7 73.0 4048.8 1980.0 867.3 2983.7 1701.7 243.5 992.0 2446.8 1604.3 1512.3 1533.0 23.1 3272.4 5396.6 1667.3 884.8 1150.5 917.2 2228.2 1601.0 1519.3 2201.2 109.4 23.8 2834.0 1084.4 1989.9 3307.5 430.7 2517.0 1457.1 2406.5 17.8 2486.8 530.4 1845.5 31.7 32.4 2092.1 2269.8 1479.8 1382.6 4479.8 1447.6 2791.4 790.8 252.3 769.2 3139.6 1955.7 236.4 357.1 3510.2 6623.0 4105.6 2341.0 2848.1 3482.8 5438.5 RPL13 "BBC1, D16S444E, L13" ENSG00000167526 "Ribosomal protein L13" P26373 16 89560677-89564542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051702 Approved Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 190000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA051702: AB_2681579" "unprognostic (5.41e-3)" "unprognostic (1.69e-1)" "unprognostic (1.14e-2)" "prognostic favorable (6.26e-4)" "unprognostic (1.57e-2)" "unprognostic (3.68e-2)" "unprognostic (7.38e-2)" "unprognostic (2.37e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-2)" "unprognostic (2.14e-1)" "unprognostic (7.57e-2)" "prognostic unfavorable (6.64e-4)" "unprognostic (4.34e-2)" "unprognostic (7.10e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" 2508.9 1855.2 1068.8 1015.2 1070.1 2207.4 2514.6 1007.8 1300.0 2885.7 1027.9 2382.3 1082.7 1830.7 799.8 2804.1 2342.7 756.7 1661.7 984.6 1007.1 1722.4 2142.4 1560.6 2106.2 1129.1 1023.0 5001.9 4316.1 896.0 1581.0 636.9 1076.3 2852.9 719.0 215.3 2413.8 826.7 2404.7 4466.0 2067.4 689.9 1159.2 2545.7 2148.6 856.8 1078.9 1718.3 1609.7 1175.1 1635.1 2301.1 2682.5 1123.0 1402.1 1524.2 1063.0 1733.2 1869.8 3083.4 2218.9 863.7 1857.6 1768.8 712.9 2316.0 2113.8 1954.1 1729.3 1484.1 700.0 1903.0 1279.4 2281.5 873.2 551.7 3534.0 666.7 817.4 3149.0 3985.0 818.9 781.2 3770.4 4759.6 1136.6 2847.0 2870.3 1870.2 2424.6 2074.1 1084.5 1380.2 4385.7 2272.4 6404.2 2180.5 2755.6 1601.9 3323.5 1128.8 2786.0 2205.4 1162.1 1491.3 2176.3 1195.0 1544.6 2735.2 665.7 3044.3 4780.1 1101.8 1132.3 1218.4 1008.8 1211.3 1626.1 1668.7 2104.6 1479.4 2863.7 1220.5 1017.1 3191.4 507.1 3779.3 2446.7 7007.7 7792.3 6813.4 5173.6 3626.5 8215.0 8509.1 6722.0 323.4 4085.8 1910.1 5071.9 5277.8 13749.1 1068.8 1070.1 1007.8 1300.0 984.6 1007.1 1129.1 1023.0 1076.3 1159.2 1078.9 1123.0 3260.3 1804.5 3489.0 39.8 9318.5 12528.7 15921.0 7329.9 8523.7 675.1 10709.1 13191.6 465.3 3808.9 4064.9 1616.6 189.7 6201.2 5935.5 1800.0 4652.6 4068.5 4125.7 2011.7 5627.8 4627.9 2937.8 3784.5 39.1 10909.9 11178.8 4536.6 2934.8 2679.4 2651.1 6392.0 5119.5 4261.1 5228.5 249.0 52.5 6292.1 2089.4 7058.1 8832.3 12884.5 8244.9 5051.4 5457.0 66.5 7569.8 1941.5 5395.5 158.3 86.4 7077.2 4715.7 3652.3 4667.7 14016.4 5245.4 7448.2 1834.7 786.9 2084.0 5936.3 5693.8 1721.1 1052.9 9022.1 16171.5 6165.5 7831.2 7839.7 7465.8 15137.1 RPL18 L18 ENSG00000063177 "Ribosomal protein L18" Q07020 19 48615328-48619184 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "NB-4: 16079.5" "Low region specificity" "Detected in all" HPA046572 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 290000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA046572: AB_2679705" "unprognostic (2.12e-2)" "unprognostic (1.86e-2)" "unprognostic (7.30e-2)" "unprognostic (2.57e-2)" "unprognostic (3.48e-3)" "unprognostic (4.76e-2)" "unprognostic (3.21e-3)" "unprognostic (2.80e-1)" "unprognostic (2.39e-1)" "unprognostic (9.15e-2)" "unprognostic (6.15e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.40e-1)" "unprognostic (3.04e-2)" "unprognostic (6.36e-2)" "unprognostic (1.27e-2)" 1000.7 1074.9 985.7 753.7 981.5 1976.6 1333.2 932.2 1170.2 1491.2 910.5 995.0 912.2 1051.5 782.6 1786.5 1415.0 719.4 754.8 924.1 955.5 756.7 974.7 730.6 1740.2 980.7 953.9 3084.6 2343.7 580.6 905.7 746.8 972.6 1262.1 814.4 139.0 1779.2 702.0 1056.9 1944.3 956.6 709.9 999.1 1151.6 1122.4 332.2 993.5 1091.5 880.0 643.0 1399.0 1017.9 1356.0 989.5 1874.4 2697.1 1148.7 1520.6 1267.0 2299.6 1455.1 1042.7 1489.0 1754.3 1471.6 2497.8 1407.6 3436.1 874.1 1007.2 803.9 1400.0 1211.2 2056.9 844.3 1349.6 3380.2 1286.3 1234.0 2438.1 2166.6 1793.6 1309.6 2633.8 3015.8 1031.9 1603.7 1760.0 1836.8 2149.2 1629.3 2043.5 1297.6 2236.5 1926.2 16079.5 1421.6 3171.4 1469.5 2058.1 1073.4 2438.4 1527.9 2370.7 1410.8 1739.1 850.4 2306.0 2082.3 641.1 1241.4 2618.1 1220.9 1032.3 1275.0 727.4 2119.8 1970.9 2939.2 1934.2 649.6 2246.7 1257.7 381.1 1022.8 217.6 1066.6 890.3 1889.0 2384.8 1921.2 1461.0 1380.1 2368.0 2373.9 1981.4 140.7 1357.8 681.2 1451.1 1707.2 3192.5 985.7 981.5 932.2 1170.2 924.1 955.5 980.7 953.9 972.6 999.1 993.5 989.5 1729.2 593.0 983.1 22.9 4066.2 4468.5 4767.6 3561.4 4933.7 393.5 3680.3 5354.2 264.0 1637.1 1809.1 708.1 143.9 3891.0 2534.2 1344.7 1387.2 1853.2 80.5 1067.0 2619.6 1812.4 1673.5 1713.1 21.7 4530.2 5344.1 1765.9 1597.9 1584.8 1021.6 2791.1 1810.1 1426.6 2225.3 134.6 28.2 3186.8 1253.2 2491.6 3341.9 221.3 3248.9 2059.4 2278.5 16.9 2958.8 1413.2 2345.1 22.6 51.3 3022.6 2516.1 1459.7 2801.6 4727.0 2534.3 1832.5 697.3 433.7 1032.1 2596.1 2246.5 283.4 558.4 5421.3 5559.5 4138.0 2961.3 3084.2 3163.6 5183.8 RPL21 "DKFZp686C06101, FLJ27458, L21, MGC104274, MGC104275, MGC71252" ENSG00000122026 "Ribosomal protein L21" P46778 13 27251309-27256691 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047252 Approved Supported "Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 34000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli fibrillar center, Endoplasmic reticulum, Cytosol" "HPA047252: AB_2680000" "unprognostic (4.79e-2)" "unprognostic (3.69e-2)" "unprognostic (1.99e-1)" "unprognostic (2.31e-1)" "unprognostic (3.57e-1)" "unprognostic (1.90e-3)" "unprognostic (2.55e-2)" "unprognostic (7.72e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.66e-2)" "unprognostic (2.42e-2)" "unprognostic (5.47e-2)" "unprognostic (4.53e-2)" "unprognostic (4.83e-3)" "unprognostic (1.28e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-1)" 1565.0 1042.6 1087.8 714.2 1108.1 2293.7 1689.3 1066.4 1946.8 2047.0 1061.5 1733.4 625.1 1329.1 725.7 1504.9 1718.1 553.6 1306.5 1047.9 1131.1 1421.7 1085.9 1181.3 1633.8 1112.2 1089.9 3100.5 2449.9 514.5 1047.0 626.6 1107.4 1381.0 803.3 419.1 1325.3 643.2 1855.2 1987.4 1471.7 594.3 1106.4 1794.1 1487.8 317.3 1103.9 1072.9 1114.9 769.6 1395.1 1631.4 1650.9 1117.2 942.9 772.1 1337.0 1086.2 1361.4 2569.1 1130.1 1664.7 1515.8 1277.2 822.1 1875.1 1700.0 3578.7 627.8 1332.5 571.7 1220.3 1552.8 1694.0 1495.8 1139.5 1410.3 2803.5 738.9 1470.3 1284.7 3871.3 1063.8 2304.6 2722.2 837.5 2112.0 1751.9 1454.0 1562.9 1181.8 865.5 1468.6 1340.3 1970.6 2398.9 1754.3 2792.4 1281.4 1446.1 2566.6 1511.2 1201.2 1111.2 1153.8 1071.6 773.3 1531.6 1390.1 1120.4 1033.9 3406.6 1619.7 563.1 731.3 895.3 1384.6 579.7 874.2 2583.3 722.1 2415.5 978.6 948.5 1201.5 493.2 1996.0 1257.2 3233.0 3717.7 2993.5 2504.4 1607.9 3347.5 4294.2 3510.3 249.1 2178.4 1308.5 2181.4 2271.1 6723.7 1087.8 1108.1 1066.4 1946.8 1047.9 1131.1 1112.2 1089.9 1107.4 1106.4 1103.9 1117.2 1464.4 1685.9 2658.5 9.4 6395.0 7645.1 5673.8 7552.7 1649.3 375.0 4496.8 3380.2 191.6 4000.5 3789.8 1565.1 143.9 5240.1 4382.0 1695.3 5290.4 3849.1 74.4 1089.9 2417.7 2670.0 2385.5 4124.1 9.0 7829.6 6183.8 2401.4 924.6 1200.5 2817.5 2227.4 4446.9 4944.4 3952.9 159.9 10.1 4869.4 2518.7 7461.4 9266.1 225.9 3957.2 3114.0 5229.4 7.5 9465.6 1525.3 6167.9 8.5 14.1 4983.3 3923.7 2403.1 2133.1 4379.8 4261.8 6230.7 1742.7 634.1 1899.8 4878.6 2645.8 650.7 1016.0 2107.5 8226.2 5507.4 5413.5 1829.5 5416.3 4837.4 RPL22L1 ENSG00000163584 "Ribosomal protein L22 like 1" Q6P5R6 3 170864875-170870208 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 651.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 912.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048060, HPA056207, HPA068294" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA048060: AB_2732544, HPA056207: AB_2683065, HPA068294: AB_2732781" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.59e-1)" "unprognostic (1.45e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-3)" "unprognostic (1.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.17e-3)" "unprognostic (4.52e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (5.12e-2)" "unprognostic (3.55e-1)" "unprognostic (1.23e-1)" "unprognostic (6.96e-2)" 41.4 32.0 10.4 64.2 12.0 93.6 46.7 10.7 20.6 25.6 9.8 36.1 19.0 24.8 17.8 75.3 32.3 17.2 23.5 10.4 11.6 27.4 47.9 25.9 75.3 11.9 11.5 34.0 47.5 8.3 22.4 17.2 12.1 25.1 33.0 7.7 34.2 15.7 9.9 46.6 32.9 26.5 11.4 67.4 38.6 13.7 11.8 39.8 16.9 6.2 63.2 61.3 38.0 16.4 153.8 169.2 54.4 632.1 156.8 912.4 165.5 152.9 349.5 121.7 78.4 72.8 34.8 472.8 34.5 143.1 379.6 39.3 136.4 390.2 67.7 28.8 24.7 43.2 21.4 166.4 632.4 88.7 60.1 670.6 775.2 38.9 409.7 189.0 418.9 257.7 30.4 29.8 672.0 194.3 650.6 49.7 849.1 58.6 31.0 857.7 19.4 72.7 305.4 337.4 9.2 45.7 15.4 75.6 72.1 29.2 105.6 77.2 196.3 23.3 175.9 47.2 216.8 47.1 36.0 76.2 420.5 53.7 489.4 2.2 9.5 4.3 13.2 12.6 26.9 47.1 19.4 17.9 10.7 34.8 12.9 14.5 2.1 28.8 17.8 51.2 13.1 6.9 10.4 12.0 10.7 20.6 10.4 11.6 11.9 11.5 12.1 11.4 11.8 16.4 153.2 9.6 43.7 4.6 379.6 197.6 240.2 260.8 198.6 13.9 185.1 397.2 18.1 55.8 111.4 20.2 4.2 89.8 241.9 111.5 66.5 160.8 37.6 128.4 279.6 138.5 144.6 266.7 3.3 232.3 297.4 169.0 146.3 116.8 106.5 202.8 103.9 129.5 184.7 8.4 4.5 240.7 93.6 187.4 101.4 36.3 139.4 148.9 78.2 2.8 108.7 54.2 69.0 7.5 10.1 400.8 137.1 89.1 651.0 421.5 99.1 94.1 60.5 21.0 46.0 189.5 472.0 67.2 58.9 511.7 247.8 98.4 173.7 260.4 197.5 356.3 RPL23A L23A ENSG00000198242 "Ribosomal protein L23a" P62750 17 28719985-28724359 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA051754, HPA077474" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 86000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli fibrillar center, Endoplasmic reticulum, Cytosol" "HPA051754: AB_2681593, HPA077474: AB_2686841" "unprognostic (1.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (9.79e-2)" "unprognostic (7.76e-2)" "unprognostic (1.91e-3)" "unprognostic (1.23e-1)" "unprognostic (9.64e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.16e-6)" "unprognostic (3.91e-2)" "unprognostic (1.54e-1)" "unprognostic (3.98e-3)" "unprognostic (2.68e-1)" 1584.8 1113.1 654.3 671.5 688.0 1394.2 1570.3 652.4 1022.2 2187.2 625.1 1445.1 612.6 1394.1 718.6 1571.9 1634.3 535.3 1187.3 618.4 650.0 1099.0 883.0 1093.0 1433.2 673.2 651.5 3435.1 1784.0 525.5 1098.5 674.5 679.4 1319.5 821.4 343.6 1355.9 639.7 2007.1 2167.8 1341.4 670.2 718.7 1621.7 1365.0 394.3 691.1 970.1 1098.0 887.1 1529.3 1516.5 1724.7 701.9 1011.7 2016.2 1187.9 1478.2 1541.3 2460.3 1167.5 919.9 1609.3 1530.9 1285.0 2069.6 945.7 2272.0 842.9 1288.6 794.8 1336.2 1604.1 2059.1 1570.9 1207.4 4393.8 1090.0 1875.4 2228.4 1393.9 2286.0 1078.5 2415.4 2592.8 1218.4 1907.0 2198.5 1679.1 1024.9 1440.9 1494.0 1555.3 1668.7 2566.5 3014.5 1145.8 2554.4 1212.9 1485.1 2158.1 2703.9 1672.0 2029.6 1233.6 1432.9 656.5 4676.5 2224.2 1655.3 2336.4 2637.5 1009.1 833.0 1177.1 985.4 1663.8 1819.6 1831.8 1323.2 1314.2 1241.1 939.6 1095.3 1931.7 552.4 4031.6 2107.3 5926.1 6793.2 5786.8 5255.4 2964.7 5683.7 6315.4 5951.4 244.7 4162.0 1738.1 3784.3 4293.0 7336.1 654.3 688.0 652.4 1022.2 618.4 650.0 673.2 651.5 679.4 718.7 691.1 701.9 987.8 862.2 1387.4 42.1 4276.8 5192.7 5364.3 4497.6 1889.4 237.4 3483.7 2581.2 292.2 2254.7 2254.3 864.4 70.9 4486.2 3010.4 1253.0 3083.4 2444.1 968.0 1089.8 2060.3 2031.0 1846.3 1943.9 13.5 4593.6 6595.0 1928.4 821.6 1503.9 1512.6 1814.9 2939.2 2626.6 2651.7 163.2 17.2 3659.6 1310.2 3406.8 5015.0 360.5 4557.4 1983.9 3066.4 14.0 3997.3 1072.1 4293.5 16.1 23.3 2801.3 3326.6 2366.6 1803.5 5056.3 2925.9 3669.2 886.9 363.6 1709.2 3461.4 2748.7 674.8 779.0 2554.1 6196.5 4927.6 3651.6 2266.4 3979.8 5957.0 RPL26 L26 ENSG00000161970 "Ribosomal protein L26" P61254 17 8377516-8383213 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030449, CAB037301" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "CAB037301: AB_796168, HPA030449: AB_10602125" "unprognostic (2.02e-2)" "unprognostic (3.73e-1)" "unprognostic (2.12e-1)" "unprognostic (2.76e-1)" "unprognostic (6.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (3.95e-1)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (7.15e-2)" "unprognostic (1.96e-3)" "unprognostic (2.73e-1)" "unprognostic (1.08e-1)" "unprognostic (5.44e-2)" "unprognostic (2.38e-1)" 2647.0 1834.7 1444.0 1225.0 1483.6 3862.9 4202.6 1437.9 2302.9 2923.7 1394.3 2148.4 1286.2 1911.1 2229.1 2565.8 2254.3 1396.5 1756.1 1402.1 1503.8 2006.1 1826.0 1615.6 3047.7 1494.3 1433.2 4732.1 3616.6 1250.6 1067.0 1536.3 1496.7 2026.5 2044.1 815.9 2073.2 1272.7 2625.9 3123.9 1921.8 1379.7 1515.1 2060.3 2137.9 548.8 1463.6 2241.2 1926.2 1911.5 2840.0 2178.2 2560.6 1538.3 2791.7 2553.3 2428.3 2899.9 4595.7 7595.7 2377.2 2357.4 3627.6 3234.3 2430.6 2732.4 1406.4 4875.0 2641.6 2899.3 1278.3 3012.9 3173.2 4954.7 3806.7 1824.4 5711.8 1893.9 2682.1 3218.0 5344.6 2835.2 2347.9 6463.5 9908.8 2638.4 7949.9 4443.9 4106.5 2739.0 2210.9 1423.8 3478.6 1967.6 3153.9 3903.4 2275.5 2924.4 1691.8 3097.3 2453.7 3094.4 4394.8 2116.9 1014.7 2144.2 1268.6 2353.7 5882.6 2142.4 2417.5 3740.1 2492.5 1270.3 1564.9 1765.2 4201.2 1119.0 1485.1 2188.6 2074.1 4071.7 1920.7 490.8 1528.6 300.6 1323.8 1277.1 1928.7 2409.5 1960.7 1734.1 1901.2 2152.5 2270.0 2008.9 167.6 1562.4 1173.0 1634.7 1803.3 3235.4 1444.0 1483.6 1437.9 2302.9 1402.1 1503.8 1494.3 1433.2 1496.7 1515.1 1463.6 1538.3 2207.3 897.4 1239.5 29.0 4966.6 5577.5 3390.4 3434.2 4618.4 256.5 5263.8 5691.4 292.0 3039.7 1994.1 1004.2 133.5 4514.0 3481.7 1395.1 3946.3 2664.5 884.0 1146.1 2485.1 2507.8 2284.5 2894.1 39.3 4897.5 7026.7 2100.3 1725.3 1470.3 1868.6 1738.7 3416.5 2960.2 3431.5 136.3 33.9 4440.7 1062.0 5356.7 6335.6 1657.9 4777.0 3085.5 3198.1 45.9 6036.5 747.5 3887.8 22.1 39.7 3561.4 3590.4 2157.9 2546.9 3577.0 3412.0 5475.1 856.5 477.7 1512.0 4011.2 2218.8 568.4 716.4 6164.5 7093.8 4568.3 3804.2 2012.8 4955.7 3367.7 RPL26L1 RPL26P1 ENSG00000037241 "Ribosomal protein L26 like 1" Q9UNX3 5 172958729-172969771 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 408.0;Spermatocytes: 316.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030449 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA030449: AB_10602125" "unprognostic (3.02e-1)" "unprognostic (1.41e-1)" "unprognostic (3.39e-2)" "unprognostic (4.12e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (2.04e-3)" "unprognostic (2.45e-1)" "unprognostic (7.51e-2)" "unprognostic (5.86e-3)" "unprognostic (3.18e-1)" "unprognostic (1.06e-1)" "unprognostic (7.17e-2)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-3)" 27.4 45.8 28.0 28.9 29.2 39.1 27.3 29.7 39.1 23.5 26.4 24.5 25.2 28.5 37.7 37.5 26.6 22.1 37.8 31.0 29.8 43.7 47.9 22.1 34.4 29.3 28.9 25.7 24.9 34.5 30.3 23.8 30.6 25.5 26.2 17.9 24.6 28.9 37.8 21.3 21.9 26.0 28.1 26.8 26.2 91.2 29.3 34.0 29.5 28.1 29.0 30.4 25.4 29.1 129.8 114.7 101.9 140.8 68.9 72.3 131.7 120.6 70.6 170.5 151.1 141.1 135.3 96.6 301.5 166.6 181.6 82.1 170.1 239.8 156.4 124.1 220.9 71.6 122.8 174.5 135.1 105.7 60.8 91.0 99.2 176.1 122.3 69.1 99.2 93.6 100.3 79.0 123.1 286.6 129.5 165.6 65.2 59.7 180.5 93.3 157.5 128.4 101.0 80.1 102.0 62.7 110.6 100.2 167.6 64.7 122.8 111.5 105.4 193.2 109.0 114.3 92.5 70.3 119.0 182.3 152.6 130.2 117.6 25.4 86.6 39.9 33.1 80.5 42.7 50.4 40.4 46.1 99.5 38.1 32.9 42.0 42.9 39.5 72.2 68.1 55.8 55.7 28.0 29.2 29.7 39.1 31.0 29.8 29.3 28.9 30.6 28.1 29.3 29.1 41.5 41.7 32.8 4.6 29.8 48.8 56.9 191.3 32.5 18.8 50.2 61.8 45.5 41.5 82.7 58.8 18.8 111.6 28.7 36.2 181.9 119.0 408.0 98.4 70.0 47.7 40.2 49.2 4.5 113.0 124.5 45.3 29.6 70.6 26.6 60.2 41.4 132.1 115.0 15.2 5.2 48.6 93.6 48.6 51.9 79.9 37.9 45.6 51.6 2.8 93.5 61.7 49.4 2.0 5.0 138.0 38.6 41.0 59.2 67.9 48.2 216.2 92.4 20.2 19.7 35.6 56.1 316.7 178.6 70.5 52.8 78.9 28.9 81.1 59.1 57.7 RPL29 "HIP, HUMRPL29, L29, RPL29P10" ENSG00000162244 "Ribosomal protein L29" P47914 3 51993522-51995895 "Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069064 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 190000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA069064: AB_2686077" "unprognostic (3.77e-3)" "unprognostic (2.72e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (2.89e-3)" "unprognostic (5.46e-2)" "unprognostic (6.79e-3)" "unprognostic (1.79e-1)" "unprognostic (2.16e-1)" "unprognostic (5.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (2.16e-2)" "unprognostic (1.98e-1)" "unprognostic (9.99e-2)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" 1695.8 1400.7 669.4 719.9 687.1 2111.2 1659.2 668.9 816.3 1854.9 645.4 1352.4 866.4 1208.8 657.8 1772.7 1470.3 645.8 1073.9 646.1 673.9 1112.9 1155.6 972.4 1348.0 697.9 665.1 2740.8 2740.5 537.5 708.8 534.7 696.9 1307.1 624.9 229.3 1478.4 550.2 2689.5 2458.5 1155.7 567.4 721.7 1239.3 1341.7 440.2 684.7 1075.5 982.6 1287.3 991.6 1339.6 1643.6 729.6 1208.7 1467.7 1123.3 1808.9 1933.5 3007.1 1603.5 1299.2 1540.3 1693.7 1396.9 1757.3 1831.7 3226.6 553.5 1292.3 1044.1 1084.1 1622.7 2689.1 802.7 1335.2 2202.3 1689.2 1892.1 3037.1 2287.6 2548.8 1630.1 3714.1 3735.4 1254.5 2210.9 1936.9 1920.9 1420.6 1338.0 2536.8 1264.3 2629.0 2238.9 3210.8 1965.5 1755.6 2463.0 1038.1 1267.3 3258.5 2211.8 2509.3 948.0 1820.6 969.6 2279.1 2378.1 706.9 1710.1 4227.3 1745.3 1001.3 1324.5 1559.7 2006.9 1615.8 2498.1 2399.9 1326.2 2953.0 1357.6 556.4 1184.0 333.4 895.8 882.9 1488.2 1886.9 1446.6 1149.2 1356.0 1749.9 1662.7 1421.4 145.3 1115.6 724.8 1154.7 1444.1 3507.7 669.4 687.1 668.9 816.3 646.1 673.9 697.9 665.1 696.9 721.7 684.7 729.6 2092.1 189.1 415.6 35.3 3749.3 3975.7 5198.9 3485.6 4465.8 234.8 4763.1 7627.1 82.4 1611.4 1245.9 711.7 102.2 2537.2 2453.7 1497.3 2181.5 1773.3 1117.1 1158.9 3170.1 1957.3 1430.9 2176.2 28.2 4573.5 5119.4 1862.6 1826.2 1529.2 694.4 3951.5 2026.4 1661.0 2373.7 107.7 33.6 3051.9 1043.6 2693.9 3423.6 4294.3 3611.5 2216.3 2218.0 37.5 2893.8 989.3 2520.1 18.1 49.2 3180.2 2816.5 1583.5 2556.8 5203.2 3720.1 3760.6 507.1 405.3 1143.9 2535.7 2110.2 564.9 465.2 5714.8 5075.9 2455.2 2765.1 5917.8 3455.9 5933.8 RPL34 L34 ENSG00000109475 "Ribosomal protein L34" P49207 4 108620569-108630412 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035139 Uncertain Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA035139: AB_10602925" "unprognostic (1.49e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-2)" "prognostic favorable (2.76e-5)" "unprognostic (2.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-1)" "unprognostic (8.22e-2)" "unprognostic (7.14e-2)" "unprognostic (2.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (3.72e-3)" "unprognostic (6.17e-2)" "unprognostic (8.96e-3)" "unprognostic (2.71e-1)" "unprognostic (1.19e-2)" 2425.0 1591.7 1002.0 785.6 1018.3 2268.5 2730.5 987.4 1524.6 3162.1 962.2 2061.8 823.2 1963.6 1544.1 2142.7 2352.9 621.4 1521.5 956.2 997.4 1752.0 1479.4 1498.1 1670.2 1010.6 982.1 4574.1 4126.6 561.6 1616.2 716.9 1015.1 2107.6 914.8 439.0 1967.4 729.0 1791.6 2675.3 1965.7 686.3 1052.9 2223.5 2008.0 507.9 1033.0 1276.7 1700.7 739.6 1511.2 2044.7 2481.9 1055.4 825.0 541.4 1026.2 1485.8 2018.1 3044.8 1023.2 1230.1 1393.2 916.9 752.8 1358.5 1395.7 2413.4 723.7 1117.5 499.4 564.9 1064.4 1792.9 1160.3 927.5 1680.3 1034.0 1087.0 2109.6 1708.0 2628.2 1118.4 2837.7 2381.1 773.6 1701.2 1839.1 1618.7 1345.9 1731.4 1357.1 1479.3 1452.6 1625.9 3123.7 1214.4 1794.1 1095.2 1473.5 1112.4 1478.1 1929.2 1234.1 1099.4 1409.8 510.1 2915.7 1881.3 805.7 957.1 2348.2 1357.7 674.5 926.3 711.3 1121.6 1020.7 1327.3 1913.0 924.1 1533.2 859.0 1744.5 3024.8 943.1 2796.0 2242.1 4811.7 7783.4 5669.6 3854.8 3005.0 6460.3 7498.4 5716.8 610.2 3571.6 1985.1 3793.7 4557.8 12314.4 1002.0 1018.3 987.4 1524.6 956.2 997.4 1010.6 982.1 1015.1 1052.9 1033.0 1055.4 3354.3 1413.4 2496.4 19.9 8040.6 12566.5 10934.5 14134.5 6505.0 343.4 12055.8 16944.0 1156.9 4838.4 5399.5 2164.7 75.0 6443.9 5150.7 1717.5 6914.3 3577.3 1527.0 2002.3 4683.1 4313.0 2720.0 3488.0 31.4 8680.5 7464.2 3471.8 2274.2 2664.1 3308.2 3093.0 5696.3 5781.3 4151.7 154.8 29.1 6030.2 3912.2 6966.0 11139.9 2023.8 7477.3 4326.2 5839.5 43.1 7738.0 1718.3 4866.1 18.1 28.5 5645.0 4899.2 4032.5 3437.1 5962.5 5302.3 9409.4 2362.8 535.0 1913.0 6558.2 3975.1 787.2 678.5 6369.9 15308.7 6380.6 7015.5 2344.3 6469.6 8608.5 RPL36A "L36A, RPL44" ENSG00000241343 "Ribosomal protein L36a" P83881 X 101390824-101396155 "Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 3019.1;Undifferentiated cells: 3021.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2852.7" "Low region specificity" "Detected in all" "HPA063979, HPA077586" Uncertain Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA063979: AB_2685164, HPA077586: AB_2686846" "unprognostic (3.38e-2)" "unprognostic (2.11e-2)" "unprognostic (7.04e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "unprognostic (4.19e-3)" "unprognostic (4.15e-3)" "unprognostic (1.28e-1)" "unprognostic (2.86e-2)" "unprognostic (2.77e-1)" "unprognostic (2.19e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (8.81e-11)" "unprognostic (1.87e-2)" "unprognostic (4.50e-3)" "unprognostic (3.57e-3)" "unprognostic (4.06e-2)" 1674.1 1002.0 390.2 179.6 390.9 502.0 1779.0 387.0 608.7 1862.0 390.9 1384.5 163.9 1291.5 278.5 1823.7 1542.2 94.6 878.4 384.9 392.9 1127.4 829.5 1066.3 304.6 398.8 389.8 3553.5 2580.0 160.2 799.7 230.4 393.6 1347.0 290.4 94.6 1304.2 219.6 1546.0 2491.5 1369.6 209.8 398.2 1575.2 1319.0 266.3 391.9 430.4 981.5 224.1 502.0 1430.5 1751.0 405.9 508.3 1045.1 465.5 237.5 640.1 1232.0 273.6 198.9 532.7 642.1 1017.6 1196.0 360.1 571.6 367.5 318.1 399.5 350.5 727.8 641.2 651.0 309.1 1445.2 205.8 1919.5 1159.3 803.0 413.1 364.3 985.5 1395.8 436.6 895.6 931.0 576.9 563.1 486.8 660.7 546.2 2852.7 288.5 1285.4 583.8 1637.7 1118.7 367.7 384.8 863.5 633.5 811.3 314.8 508.8 116.8 506.3 608.3 459.4 238.4 806.3 187.0 206.4 369.8 477.2 350.9 330.0 475.0 470.0 223.6 749.5 240.3 130.7 562.7 109.4 608.3 591.8 1102.4 1242.0 1212.6 866.9 814.7 957.9 1322.5 1179.8 51.0 760.6 615.8 919.8 678.7 1804.2 390.2 390.9 387.0 608.7 384.9 392.9 398.8 389.8 393.6 398.2 391.9 405.9 309.5 439.1 987.0 0.0 1100.1 917.4 432.3 574.6 595.8 28.9 1600.3 970.8 16.1 885.0 946.8 174.7 14.6 762.3 615.9 641.2 434.3 1235.1 9.4 124.9 331.6 566.0 1100.8 1215.5 0.0 3019.1 1125.2 523.5 315.0 164.3 1272.4 137.9 1387.8 738.4 609.1 15.2 0.0 2744.0 183.1 2089.7 1144.3 49.3 1055.9 565.6 524.7 0.0 1620.0 187.9 710.6 0.0 0.0 2338.4 1805.5 418.6 559.4 350.6 1349.6 611.7 329.9 41.2 236.7 512.1 467.7 28.7 99.3 758.7 1122.1 751.4 875.8 153.1 3021.8 351.4 RPL36A-HNRNPH2 ENSG00000257529 "RPL36A-HNRNPH2 readthrough" X 101391011-101412297 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 39.9;Club cells: 29.1;Fibroblasts: 8.8;granulocytes: 27.8;Respiratory ciliated cells: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: AB_2686846" "unprognostic (3.69e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.65e-3)" "unprognostic (1.63e-1)" "unprognostic (2.96e-1)" "unprognostic (1.79e-1)" "unprognostic (5.34e-2)" "unprognostic (2.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (1.49e-3)" "unprognostic (2.04e-4)" "unprognostic (1.56e-1)" "unprognostic (4.81e-2)" "unprognostic (3.94e-1)" 155.5 114.7 141.9 147.6 149.9 473.9 371.3 140.5 211.3 169.5 142.0 178.1 120.3 131.9 91.3 82.4 124.0 56.9 68.9 139.2 147.0 103.1 136.9 84.1 206.9 145.8 140.6 430.7 198.7 116.1 0.3 117.0 146.1 111.6 133.6 38.7 163.1 96.2 194.2 115.9 142.0 89.7 152.1 149.1 138.2 32.9 147.3 348.5 82.7 188.2 223.7 208.3 0.5 153.8 479.9 63.6 351.8 196.0 556.6 603.8 207.1 411.5 307.5 363.4 528.3 37.6 249.6 1272.3 379.1 379.3 282.1 312.4 692.9 639.6 308.0 494.4 334.8 589.7 99.9 58.4 726.0 839.5 372.7 837.9 498.0 458.3 744.0 628.2 359.2 413.5 590.6 507.6 266.5 119.0 364.7 535.8 425.9 1038.7 262.3 388.8 984.7 647.3 412.1 29.5 230.9 445.6 512.1 373.3 416.7 288.6 171.7 707.0 594.4 115.8 314.9 330.7 357.0 374.5 651.9 710.4 186.8 1188.4 141.9 97.1 324.6 105.0 284.3 334.8 348.1 373.2 363.3 332.4 450.1 354.6 364.2 357.9 57.5 277.5 292.2 306.2 274.4 605.1 141.9 149.9 140.5 211.3 139.2 147.0 145.8 140.6 146.1 152.1 147.3 153.8 0.0 12.8 39.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.5 0.0 0.0 8.8 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 RPL36AL RPL36A ENSG00000165502 "Ribosomal protein L36a like" Q969Q0 14 49618530-49620626 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: AB_2686846" "unprognostic (1.55e-2)" "unprognostic (2.44e-2)" "unprognostic (8.73e-2)" "unprognostic (3.15e-3)" "unprognostic (1.52e-1)" "unprognostic (2.55e-2)" "unprognostic (1.31e-1)" "unprognostic (6.37e-2)" "unprognostic (4.18e-2)" "unprognostic (1.38e-3)" "unprognostic (2.29e-1)" "unprognostic (4.72e-1)" "unprognostic (1.16e-3)" "unprognostic (8.32e-2)" "unprognostic (2.80e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.00e-1)" 279.7 310.9 234.2 246.4 241.7 404.2 328.6 232.1 349.8 381.8 221.4 331.8 260.5 280.7 492.7 277.4 315.9 162.6 273.2 225.1 244.6 255.3 372.3 240.5 311.9 244.4 237.3 501.3 628.8 220.0 252.9 176.7 240.6 250.8 248.8 102.0 327.5 253.2 378.6 247.6 284.9 197.9 242.0 294.2 360.3 137.6 240.5 283.4 211.2 206.5 377.1 297.8 285.9 246.2 635.8 473.9 330.1 192.6 471.3 649.8 194.9 508.9 569.9 475.4 534.7 499.0 426.1 833.4 474.5 430.3 327.9 443.5 287.6 441.3 554.8 288.1 331.1 521.6 527.5 652.8 595.1 838.8 426.0 667.8 668.2 362.7 485.9 553.7 614.6 367.3 339.5 714.4 372.8 831.7 496.5 752.6 186.0 452.1 482.0 308.6 519.5 449.5 730.7 964.2 290.3 178.1 448.5 350.8 544.1 313.0 762.2 460.1 468.2 291.3 463.0 382.3 399.8 427.6 487.0 842.7 210.5 376.9 283.7 1308.9 603.0 935.1 823.8 582.2 1113.2 959.3 1070.1 1040.5 614.8 729.1 984.7 937.6 654.0 806.3 542.2 1008.3 1096.2 1506.1 234.2 241.7 232.1 349.8 225.1 244.6 244.4 237.3 240.6 242.0 240.5 246.2 453.2 307.7 395.4 11.4 666.4 945.7 1352.2 1151.7 422.3 110.9 674.6 1022.1 662.4 652.0 643.5 312.6 25.0 690.0 778.0 871.5 995.9 739.8 614.3 490.0 431.4 515.5 366.2 535.9 14.1 1371.2 720.9 523.6 381.3 543.7 716.4 369.2 591.8 920.1 778.5 80.8 16.0 793.7 520.8 814.1 1020.0 236.4 725.7 585.0 843.1 22.5 1045.3 368.1 930.0 11.6 22.9 1311.2 1063.8 534.1 853.2 1279.2 1151.2 1194.4 579.1 127.7 486.4 693.6 898.3 364.7 150.2 390.6 839.3 516.3 888.1 355.4 620.5 1412.3 RPL4 L4 ENSG00000174444 "Ribosomal protein L4" P36578 15 66498015-66524532 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034600 Uncertain Approved "Nucleoli,Nuclear bodies,Endoplasmic reticulum,Cytosol" Yes No 1300000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoli, Nuclear bodies" "HPA034600: AB_10601483" "unprognostic (1.51e-2)" "unprognostic (3.77e-1)" "unprognostic (6.02e-2)" "unprognostic (3.68e-2)" "unprognostic (6.23e-3)" "unprognostic (1.03e-1)" "unprognostic (1.90e-2)" "unprognostic (3.20e-2)" "unprognostic (3.73e-1)" "unprognostic (2.85e-1)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.20e-5)" "unprognostic (1.27e-1)" "unprognostic (5.60e-2)" "unprognostic (4.63e-2)" "unprognostic (2.27e-1)" 831.6 565.7 367.7 738.6 404.0 1928.0 2030.6 377.1 545.7 1385.7 370.7 970.8 451.2 1276.0 1088.2 1289.4 1454.2 776.9 914.1 385.6 388.6 751.5 914.9 666.3 1630.2 376.4 380.9 3022.1 1740.5 954.0 504.0 746.1 386.6 709.1 1143.5 350.6 1234.8 1092.1 1314.7 1327.1 507.9 1353.5 383.2 776.9 643.8 296.4 373.4 1883.4 1289.5 1921.7 2451.3 1322.4 782.5 406.8 1192.9 2343.4 973.0 1646.3 4272.4 7697.6 1710.1 1416.1 2899.7 2143.0 1648.1 2611.3 2025.2 4676.6 1572.3 3396.6 1011.9 2105.0 7026.5 5476.3 2352.2 1301.4 4208.3 2872.9 1955.7 2201.2 6007.7 3042.0 1376.1 7627.4 6980.3 2334.4 9237.8 2620.8 3489.1 2180.2 2682.6 1785.2 3252.1 1956.0 2044.2 1348.1 2136.9 2634.2 1661.9 2256.2 2213.4 4588.3 2958.1 2321.4 1718.4 1794.6 872.3 2447.5 3515.4 2022.2 1812.5 4303.4 2059.2 1111.1 1662.1 1048.4 2297.9 1736.5 2937.8 3118.9 1368.2 4015.4 1281.7 46.4 455.3 62.2 359.4 370.9 668.1 711.1 698.6 506.5 586.8 644.5 888.5 721.6 26.9 478.1 361.3 372.8 589.8 1758.0 367.7 404.0 377.1 545.7 385.6 388.6 376.4 380.9 386.6 383.2 373.4 406.8 393.9 451.9 1004.9 28.1 1553.4 2423.4 2769.6 2082.8 1295.3 122.6 1594.0 1140.4 403.3 760.7 1165.2 342.1 81.3 2059.9 1055.8 364.9 1651.3 1162.8 672.5 337.9 821.0 840.2 761.1 1195.8 26.2 2141.0 3735.7 879.7 467.9 430.0 945.5 899.2 711.0 715.5 1211.2 40.4 23.9 1089.8 636.8 1281.3 2031.3 1392.4 1334.0 991.6 1088.5 27.2 1920.9 417.7 1196.8 15.1 30.0 1239.9 737.1 996.0 1019.5 2031.3 370.6 1572.3 603.9 169.9 460.2 1196.4 934.7 376.4 454.9 1632.1 2583.2 2398.3 1289.5 1184.6 1371.2 2628.6 RPL5 "L5, PPP1R135, uL18" ENSG00000122406 "Ribosomal protein L5" P46777 1 92832013-92841924 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Cancer-related genes, Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043717, HPA054444" Approved Supported "Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol" NA NA 430000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoli, Nucleoli rim" "HPA043717: AB_10964719, HPA054444: AB_2732584" "unprognostic (5.81e-3)" "unprognostic (3.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (9.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.03e-3)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.98e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.81e-5)" "unprognostic (2.26e-2)" "unprognostic (3.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-1)" 1236.3 1035.1 515.2 786.9 538.3 1743.3 1798.7 522.4 778.1 1690.1 510.7 1412.8 798.0 1295.2 1388.7 1185.6 1420.7 647.6 890.3 487.5 544.8 858.2 794.9 794.7 1435.7 527.8 511.9 3356.4 2236.0 695.4 869.5 736.1 541.3 1103.1 982.0 346.6 1189.5 847.1 1115.8 1320.8 960.1 962.1 549.0 899.0 1135.5 374.3 528.7 1351.4 1179.5 830.7 1438.8 1309.6 1274.2 552.5 2211.5 924.6 1611.4 1369.2 2045.7 4096.6 2577.6 1283.0 1703.7 1560.0 1108.9 2467.5 933.6 4112.3 2002.9 1451.6 1477.1 1370.3 1871.2 2405.7 1976.3 1314.2 2557.4 2142.3 1402.4 2303.5 2447.2 3322.0 864.6 3382.6 3711.3 1390.4 3027.2 2813.9 2191.6 2129.9 2706.3 2106.7 1814.5 1247.7 2665.7 3741.2 2497.9 1659.1 1724.1 2407.7 3118.5 2702.2 1912.0 1798.7 1367.2 1632.0 836.3 2298.6 3961.6 1316.4 1268.8 4480.6 1345.5 781.6 1429.6 1498.4 2357.4 1290.8 1314.5 2793.5 531.3 2814.4 544.2 234.9 665.6 101.3 758.7 619.1 1520.2 1320.3 1385.5 1151.0 1138.3 1105.7 1729.8 1570.9 56.7 1005.7 552.2 942.7 1140.0 2356.3 515.2 538.3 522.4 778.1 487.5 544.8 527.8 511.9 541.3 549.0 528.7 552.5 1586.8 653.9 1042.2 29.7 3056.7 2843.0 4383.1 2206.0 3168.8 339.6 3182.0 5498.6 375.2 1522.7 1266.7 412.0 89.6 2557.1 2009.8 595.2 1993.7 1697.1 1438.3 840.8 2334.8 1567.8 1236.6 1980.6 35.0 2708.5 4211.6 1464.3 978.1 1009.8 1041.9 2287.9 1546.3 1087.2 1452.5 146.4 33.8 1986.9 720.2 1758.7 2200.6 1189.4 2829.9 1536.8 1406.9 35.6 2171.5 806.3 1969.1 27.2 37.7 1851.6 1567.8 2156.4 2067.8 3935.4 1225.7 2454.6 571.0 298.8 1051.8 2546.2 2122.7 682.8 501.7 3198.9 2893.0 2613.1 2318.2 2797.0 2572.8 3991.1 RPL7 "humL7-1, L7" ENSG00000147604 "Ribosomal protein L7" P18124 8 73290242-73295789 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 17748.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058373 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 380000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA058373: AB_2683694" "unprognostic (3.75e-1)" "unprognostic (3.60e-2)" "unprognostic (6.99e-2)" "unprognostic (1.80e-1)" "unprognostic (2.37e-2)" "unprognostic (7.32e-2)" "unprognostic (1.45e-2)" "unprognostic (3.41e-2)" "unprognostic (8.31e-2)" "unprognostic (4.78e-2)" "unprognostic (1.76e-1)" "unprognostic (3.09e-1)" "unprognostic (1.63e-2)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.14e-1)" "unprognostic (2.31e-1)" 2254.0 1352.4 835.1 1322.3 886.2 3071.3 3298.9 846.6 1224.8 2495.7 843.0 1841.6 1316.8 1844.3 1839.2 2058.4 2057.2 1033.9 1342.4 799.0 860.0 1634.0 1593.8 1327.3 2285.6 859.3 828.4 4528.2 3067.3 1217.6 1195.0 1202.5 870.8 1650.4 1681.7 889.4 1843.5 1261.6 2391.6 2826.4 1420.5 1381.5 914.8 1388.9 1853.0 527.0 848.2 2225.3 1616.5 1832.1 2665.8 1978.5 2103.5 900.4 2902.0 2050.6 2163.3 2615.7 4308.7 5473.7 2120.8 3100.6 2474.6 2069.9 1621.0 2487.3 2940.4 8517.8 2467.6 2517.8 1409.2 2703.0 2888.8 3960.2 3204.7 2313.1 2394.1 4682.9 2687.5 2594.4 2583.2 3343.2 2298.0 5174.5 4574.0 1921.5 5950.9 3797.5 3412.0 2840.5 4261.7 3140.1 2980.2 2448.1 5345.2 5080.8 2528.5 5238.5 2182.9 3552.8 2474.4 3353.9 3241.5 2848.0 2977.1 2160.3 1454.9 17748.7 4599.1 1766.2 4497.4 4312.2 3227.1 1575.4 2407.3 2031.7 2913.1 1799.2 2782.6 5514.9 1649.7 4062.8 2654.8 3331.3 7192.1 1787.5 6932.4 5967.0 12630.9 14333.5 12042.7 9069.1 9565.2 12188.2 17585.4 12433.8 894.5 9240.8 5307.0 7970.3 10207.4 26909.6 835.1 886.2 846.6 1224.8 799.0 860.0 859.3 828.4 870.8 914.8 848.2 900.4 622.3 817.3 1610.8 26.1 2654.7 8054.8 9929.5 10766.1 1684.6 268.0 5251.9 4462.2 623.2 2396.3 3812.0 1311.3 125.1 4882.8 1798.3 926.5 5576.1 2795.4 1720.0 1068.3 2371.5 2338.1 1617.8 1779.1 27.0 5044.8 7032.5 2096.9 721.7 1300.7 1491.1 1110.8 2680.0 1876.1 3252.9 94.2 27.6 3112.1 3057.8 3661.5 5169.4 806.4 4246.4 1893.5 3705.1 25.3 4752.6 1792.8 3105.1 19.6 33.6 3149.3 2514.2 2310.6 952.9 5766.4 2274.7 5797.7 1454.2 380.6 1459.4 4118.3 2651.4 953.5 374.0 2143.1 9487.1 4878.7 2546.9 2145.3 4018.0 7816.6 RPL8 L8 ENSG00000161016 "Ribosomal protein L8" P62917 8 144789765-144792587 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 6599.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045095, HPA050165" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 170000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA045095: AB_2679213, HPA050165: AB_2681038" "unprognostic (2.52e-2)" "unprognostic (2.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (9.84e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (4.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.54e-1)" "unprognostic (9.28e-2)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (2.31e-1)" "unprognostic (4.13e-2)" 1100.4 864.4 197.2 397.5 201.1 1020.7 1162.7 197.3 361.6 1387.5 199.5 1138.7 688.7 1042.4 63.7 1406.6 1118.6 146.4 962.6 174.2 193.7 889.8 709.6 796.1 424.5 214.1 195.2 2192.7 2021.1 150.3 784.2 264.4 199.9 974.9 110.0 22.9 1320.1 201.8 1651.4 1800.7 885.7 115.6 222.7 918.6 1003.5 304.7 218.2 150.0 739.9 194.0 196.4 1099.7 1240.2 218.1 2486.1 2860.3 200.1 874.6 220.0 496.0 1913.2 1747.7 325.3 522.4 369.7 2518.8 1299.5 3296.6 2461.9 208.4 174.3 1470.7 263.8 609.1 95.7 1446.1 3218.7 1962.1 2166.5 1805.2 546.9 1299.9 1027.5 537.1 680.7 235.9 400.8 246.5 387.8 703.1 2695.3 742.2 226.0 6599.2 1862.9 1754.6 1865.3 674.7 3196.8 1806.5 1154.4 3160.7 280.1 1842.0 1215.9 2028.4 1677.7 899.2 2541.5 81.0 2093.2 1233.3 1573.7 689.8 2622.6 1454.9 2127.3 1344.2 1235.8 2856.3 1372.4 2117.5 968.7 534.8 1464.1 574.8 1160.0 1504.9 1934.6 2970.9 1937.9 1430.4 2051.1 2991.2 2181.6 1718.2 166.1 1469.4 1479.6 1129.7 2070.5 5473.9 197.2 201.1 197.3 361.6 174.2 193.7 214.1 195.2 199.9 222.7 218.2 218.1 2510.5 852.5 1309.5 28.7 4225.5 6439.6 7085.5 5724.6 4563.8 424.0 6122.9 9469.1 1049.0 1988.8 2513.8 1028.1 268.9 4313.8 1790.8 1780.8 4433.5 2429.1 891.2 1083.4 2465.0 2455.7 1698.3 2407.7 24.0 5851.2 6733.6 2161.3 1804.3 1452.8 1044.4 2390.5 2116.1 1309.7 3031.0 166.5 28.5 3563.5 1698.8 2811.4 5097.7 2782.3 3122.7 2281.9 3520.0 30.9 2951.5 1300.3 1607.7 16.1 32.8 3402.4 3311.1 1432.3 3168.7 6500.7 3930.7 4195.9 961.7 689.1 1078.1 2701.0 3865.8 591.8 583.4 5817.5 8224.4 4365.8 2704.6 3472.7 4291.2 7522.7 RPL9 L9 ENSG00000163682 "Ribosomal protein L9" P32969 4 39452587-39458931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 2512.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003372 Approved Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 180000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA003372: AB_1079843" "unprognostic (1.08e-3)" "unprognostic (2.14e-1)" "unprognostic (1.24e-1)" "unprognostic (8.06e-3)" "unprognostic (5.59e-2)" "unprognostic (1.27e-2)" "unprognostic (3.16e-2)" "unprognostic (2.14e-1)" "unprognostic (8.58e-2)" "unprognostic (6.68e-2)" "unprognostic (2.50e-2)" "unprognostic (7.85e-2)" "prognostic unfavorable (7.34e-4)" "unprognostic (1.34e-1)" "unprognostic (2.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-2)" 1868.9 1181.0 377.9 809.5 384.9 2487.2 2132.6 378.2 2512.5 2407.6 382.9 1776.6 737.5 1418.3 2338.6 1568.7 1896.6 785.0 1168.4 368.3 462.3 1318.1 1056.3 1130.2 613.9 381.0 381.1 3607.4 2794.6 510.7 1060.0 419.0 382.5 1562.6 605.5 314.2 1387.6 681.5 1550.4 2153.4 1327.8 551.1 407.5 1400.1 1484.5 386.8 388.4 43.6 1072.2 1767.5 705.8 1675.7 1773.4 395.9 52.4 41.7 2173.3 48.2 57.0 90.0 72.9 1109.3 1618.3 1306.1 981.0 131.1 1243.5 2771.5 93.8 1081.2 1040.1 1169.0 67.3 79.3 1422.3 964.2 2080.2 80.0 415.4 131.2 81.3 153.2 711.1 113.8 3249.4 56.1 1445.8 1907.5 69.6 70.4 2126.4 1196.8 60.9 69.4 1556.5 163.4 1954.7 1523.9 57.6 1417.2 2327.7 76.3 1656.7 63.7 74.3 915.0 31.6 899.8 115.5 1976.1 1864.0 98.7 63.2 51.1 72.1 1486.9 134.2 1806.3 2754.2 2483.9 1456.9 1717.2 56.6 447.2 556.1 171.7 664.4 585.3 1320.8 1566.4 1311.6 919.0 779.1 1361.8 1804.5 1436.1 94.8 927.3 456.8 1013.2 1101.2 2263.3 377.9 384.9 378.2 2512.5 368.3 462.3 381.0 381.1 382.5 407.5 388.4 395.9 1634.0 663.4 908.4 2.3 3629.4 4132.6 5621.6 3089.9 1994.2 406.0 4149.6 3833.2 428.0 2051.8 1359.8 709.9 160.6 3011.2 2723.2 1300.0 2733.2 2184.8 1549.9 1126.9 2738.2 2121.2 1850.2 1755.0 3.0 4399.8 5910.8 1698.9 828.7 1534.0 913.2 2226.7 2439.5 1991.3 2775.3 198.5 3.2 3581.7 1053.8 3282.8 3322.0 1707.8 4819.6 2242.3 1851.6 2.8 4568.2 1398.0 3045.4 3.0 3.6 3145.0 2925.6 2394.1 1420.3 4718.4 2823.2 3698.3 656.7 581.0 1512.0 3760.1 2630.9 684.0 593.6 2325.1 4675.5 3400.0 2937.1 2567.2 3793.6 5564.6 RPLP2 "D11S2243E, LP2, MGC71408, P2, RPP2" ENSG00000177600 "Ribosomal protein lateral stalk subunit P2" P05387 11 809965-812880 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053635, HPA075365" Approved Approved "Nuclear speckles,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 2900000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" "Nuclear speckles, Cytosol" "Mitotic spindle" "HPA053635: AB_2682212, HPA075365: " "unprognostic (6.98e-3)" "unprognostic (2.21e-1)" "unprognostic (4.57e-2)" "unprognostic (8.63e-2)" "unprognostic (2.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.63e-1)" "unprognostic (2.98e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (6.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-2)" 2013.7 831.3 1119.2 993.1 1162.5 2166.9 1656.6 1099.7 1368.9 1256.2 1084.1 1277.1 1016.8 930.2 701.6 1241.3 1240.4 564.0 869.3 1057.5 1116.3 885.0 657.0 851.0 1924.7 1138.0 1095.8 2092.8 2087.8 545.7 595.5 830.9 1154.3 925.8 887.8 180.9 1908.3 775.7 1802.7 1760.4 1191.7 624.4 1204.8 1543.8 1006.0 377.6 1167.5 1545.7 785.0 936.1 1715.4 1075.5 1137.9 1217.7 2773.5 2229.6 1070.4 1864.1 2343.2 2458.2 2389.5 1728.2 1285.0 2090.8 1638.4 3307.6 2218.5 3851.6 1225.0 1629.9 1107.9 2546.7 1786.2 2778.3 836.3 1713.6 8117.9 1901.7 1416.9 3996.4 2837.3 3540.8 1905.4 3393.9 4684.6 764.1 2182.7 1860.8 2111.9 2798.2 3432.2 2040.5 1317.9 2656.6 2969.5 6002.3 3188.8 3394.5 6045.3 3345.1 1465.6 4369.9 1759.0 1281.0 2222.2 3142.1 1118.5 2825.8 3582.4 885.1 1198.9 3577.2 1881.2 1142.3 1393.9 964.1 1981.6 3838.4 3778.8 3419.3 1790.5 2952.3 1340.6 1565.3 3908.1 1299.1 4402.2 3129.1 6208.3 10718.3 8296.0 6323.4 4273.6 9867.1 10158.6 8083.9 529.9 4310.4 2525.7 5882.9 5140.5 13330.7 1119.2 1162.5 1099.7 1368.9 1057.5 1116.3 1138.0 1095.8 1154.3 1204.8 1167.5 1217.7 1311.8 1067.3 1685.0 16.3 5889.9 6113.3 6658.4 2808.0 2619.1 206.2 5955.7 4736.9 638.4 2505.0 1972.2 1601.9 79.2 5046.4 3469.2 2296.4 2592.4 3688.3 1403.0 1105.9 2434.1 2724.8 2370.2 3482.2 18.6 7413.9 8045.8 2074.3 1401.2 1787.6 1721.9 1543.2 4028.6 3068.9 4514.0 146.4 17.8 5925.5 870.8 5458.4 6404.8 3133.4 6393.4 3169.4 2986.4 27.2 5854.8 1052.2 5787.9 6.0 19.0 5201.1 4547.7 2821.7 2403.4 6640.3 4473.8 4234.1 900.4 235.5 1991.9 3688.9 2346.3 1123.1 2093.1 4264.4 7887.4 5841.1 4889.3 1629.7 6189.1 7014.0 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871952-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 19.2 13.9 7.8 12.9 8.8 25.9 17.3 8.2 10.6 14.1 7.3 15.3 9.3 15.8 14.1 18.0 14.9 12.7 22.6 8.8 8.4 16.3 15.1 13.1 21.0 7.1 7.3 18.1 11.0 23.0 8.0 18.5 7.6 12.1 15.1 13.2 14.5 12.2 31.1 17.9 12.4 16.4 8.3 15.0 14.3 28.6 7.7 21.7 12.2 22.2 22.4 17.0 14.2 10.6 82.2 53.2 55.0 66.5 34.4 37.6 19.4 57.0 51.1 93.3 98.3 90.6 64.1 48.1 42.6 36.4 60.9 56.0 73.9 50.5 95.3 77.2 51.3 32.7 31.1 73.0 33.0 66.7 39.1 30.9 32.4 70.5 79.1 39.6 54.1 43.5 65.7 42.6 62.6 50.8 77.4 89.8 33.9 46.4 59.8 42.9 46.7 50.4 35.6 38.2 29.9 29.9 33.1 23.8 68.2 50.0 64.8 41.3 31.2 46.3 46.3 26.5 119.6 28.7 79.4 104.4 57.9 35.4 36.4 9.2 30.0 27.1 25.2 30.7 27.5 31.7 28.7 28.0 35.1 28.1 24.6 27.0 3.5 25.4 26.2 32.8 33.0 27.6 7.8 8.8 8.2 10.6 8.8 8.4 7.1 7.3 7.6 8.3 7.7 10.6 31.4 32.1 16.9 14.0 28.7 34.4 27.5 51.8 23.9 19.2 16.7 28.2 45.7 27.1 31.4 14.7 18.8 60.6 33.7 9.4 31.3 41.9 95.9 18.9 26.1 25.2 19.8 38.5 18.0 35.0 68.1 28.0 13.3 17.9 23.5 33.3 21.4 14.3 58.1 16.8 19.4 21.0 30.5 23.9 29.3 49.9 28.9 24.7 23.2 11.2 32.2 23.3 15.5 17.6 19.6 31.3 12.5 29.3 20.6 18.8 12.5 36.5 21.6 24.3 39.5 30.1 36.9 77.9 54.2 20.2 34.0 33.8 23.7 28.6 17.6 27.6 RPS11 S11 ENSG00000142534 "Ribosomal protein S11" P62280 19 49496365-49499708 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049719 Uncertain Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 39000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA049719: AB_2680860" "unprognostic (1.49e-3)" "unprognostic (3.71e-2)" "unprognostic (1.22e-1)" "unprognostic (1.50e-2)" "unprognostic (5.89e-3)" "unprognostic (3.57e-1)" "unprognostic (1.04e-2)" "unprognostic (4.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.47e-1)" "unprognostic (5.68e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (5.19e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-1)" "unprognostic (1.71e-3)" 2814.3 1967.1 2353.0 1926.7 2400.8 5134.9 4378.8 2317.2 2969.3 3860.2 2321.9 2702.6 1771.3 2682.7 2738.1 2407.0 3426.0 1647.5 1778.5 2271.3 2375.3 2155.4 2117.7 1996.8 4054.9 2375.8 2309.1 6075.5 3741.4 1881.9 2119.6 1859.8 2411.6 2569.3 2712.5 1006.4 2752.4 1960.9 3200.5 3819.2 2355.1 2297.6 2434.1 2818.2 2473.8 735.7 2397.5 3791.6 1978.6 3380.1 4757.2 2689.4 2908.0 2437.6 2932.3 4522.4 3340.7 5169.4 4778.9 7228.3 2239.9 2418.7 4891.5 3444.6 3294.2 3167.0 2392.5 7154.4 1461.9 3373.2 1470.8 1926.2 4003.2 4879.0 3375.9 3065.7 6870.8 4318.3 2858.4 4634.4 4446.2 7694.0 3083.3 7191.2 7968.8 2279.2 5867.3 5774.3 5106.5 4307.3 4374.9 3709.1 3792.3 3324.7 3612.0 5845.5 3067.8 7346.6 4594.6 3450.4 4209.9 3875.7 5006.0 6932.7 3555.4 4741.2 1646.4 5505.8 3793.8 3223.4 1790.9 7907.9 2886.2 2667.3 2377.5 1302.4 3236.1 3646.3 6191.7 5179.5 1104.6 5297.2 2335.7 1161.8 2103.1 653.8 1900.0 1810.3 2537.9 4890.5 2741.7 2206.3 2979.8 4589.4 3192.9 2762.8 507.2 2120.9 1563.8 3733.9 2382.4 6125.5 2353.0 2400.8 2317.2 2969.3 2271.3 2375.3 2375.8 2309.1 2411.6 2434.1 2397.5 2437.6 820.0 836.6 1502.6 30.0 2589.7 2685.3 2499.6 1615.7 971.5 289.1 1028.9 947.2 716.6 1155.3 1344.7 474.5 143.9 1915.2 1891.9 1130.4 1216.9 1295.8 900.1 1044.9 2292.8 1236.5 1501.5 1404.7 9.6 2816.1 3575.5 1178.0 550.0 1527.0 1341.6 1228.9 1633.8 1645.8 1898.6 94.2 12.1 2720.4 612.3 2780.4 3206.1 1773.6 3212.5 1749.5 1538.5 22.5 2825.6 1123.6 2614.9 10.1 22.3 2021.0 1960.1 1538.8 1006.3 2063.5 1353.7 1873.6 857.0 493.5 874.4 2214.3 2008.7 603.1 589.5 1334.2 3413.1 2356.3 1587.9 1273.7 2434.5 2570.3 RPS12 S12 ENSG00000112306 "Ribosomal protein S12" P25398 6 132814569-132817564 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006124, HPA006365" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 450000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "Golgi apparatus, Vesicles" "HPA006124: AB_1856460, HPA006365: AB_2667570" "unprognostic (6.58e-2)" "unprognostic (3.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (6.37e-2)" "unprognostic (4.95e-3)" "unprognostic (1.46e-1)" "unprognostic (3.95e-2)" "unprognostic (1.01e-2)" "unprognostic (2.31e-1)" "unprognostic (7.04e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-1)" "unprognostic (5.66e-2)" 2199.7 1325.2 1393.3 1767.2 1454.1 5388.1 3551.2 1388.1 2027.8 2357.3 1375.8 1849.3 1597.8 1747.6 1664.7 2450.9 2149.5 1415.7 1311.3 1347.6 1419.0 1576.6 1443.7 1565.4 3948.0 1445.0 1406.0 4883.9 3660.2 1000.1 871.2 1633.7 1443.1 1696.0 1905.2 608.3 2167.8 1216.4 1965.9 3365.2 1692.7 1357.1 1484.2 2110.3 1718.3 682.0 1446.6 2534.1 1959.6 1376.9 3053.4 2011.6 2108.4 1482.0 1993.8 1568.3 2260.4 3581.3 4521.2 5855.0 2728.8 2502.9 3598.4 2772.7 2665.2 3294.5 1880.3 4497.8 3443.9 3368.1 1338.8 1900.3 2613.1 4373.5 2576.9 2895.0 3346.5 3013.3 1944.0 4743.1 5047.1 8481.4 2221.0 6167.0 7332.7 2340.5 8322.4 4658.3 3754.7 3556.4 5166.0 2858.9 3487.9 4342.3 3620.8 5030.3 2772.9 3420.0 2533.0 3993.0 1799.7 2884.6 3698.6 2185.9 1991.3 1573.0 833.4 5314.3 7184.2 2173.7 2276.5 8489.5 3027.8 1121.1 3111.7 3721.2 4696.8 4153.6 4104.8 3493.8 3635.1 5063.0 1621.7 599.0 1545.5 220.8 2412.5 1426.7 3728.9 4156.1 4210.9 3131.6 1971.7 3564.5 5201.1 4454.7 151.1 2031.9 1170.8 2722.3 2519.7 7450.3 1393.3 1454.1 1388.1 2027.8 1347.6 1419.0 1445.0 1406.0 1443.1 1484.2 1446.6 1482.0 3755.5 1660.2 3063.5 22.9 9470.7 8277.4 8259.7 3758.1 8926.6 531.5 10637.2 15674.0 827.7 3777.4 2693.4 1237.8 179.3 7566.9 6150.1 1808.1 4574.3 4058.0 792.6 1406.5 4602.8 3829.0 2863.4 5499.5 18.9 8085.7 9433.9 3353.4 3537.2 2309.6 1773.2 3890.7 4755.4 5136.7 5871.9 212.0 17.7 6806.4 1116.9 6161.6 5357.0 2335.6 6075.0 4790.9 3938.0 20.6 6667.5 2216.0 5160.7 10.1 25.0 6009.9 4480.8 2990.3 4762.0 10484.3 3517.1 5647.3 792.4 713.1 1617.2 5397.5 3117.8 1035.0 3063.2 11325.5 10512.6 7894.9 7990.4 4517.7 6783.0 9815.1 RPS17 "MGC72007, RPS17L, RPS17L1, RPS17L2, S17" ENSG00000182774 "Ribosomal protein S17" P08708 15 82536750-82540459 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 5841.9;Extravillous trophoblasts: 6575.5;Prostatic glandular cells: 6309.4;Urothelial cells: 5768.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055060 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 340000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA055060: AB_2682686" "unprognostic (3.37e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-2)" "unprognostic (6.90e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.49e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.83e-1)" "unprognostic (5.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.31e-1)" 1722.3 1537.3 1226.9 1519.3 1244.9 3816.2 3065.8 1206.6 1768.4 1818.7 1277.0 1724.0 1318.8 1489.3 1967.3 2266.9 1763.0 881.9 1192.2 1197.9 1253.8 1298.7 1646.6 1132.3 2832.4 1261.6 1218.6 3571.4 3388.7 859.1 987.5 1099.1 1264.1 1418.3 1477.9 477.2 2051.9 967.4 1588.9 2566.0 1319.4 1188.3 1265.4 1560.6 1555.5 375.1 1245.4 2012.1 1216.9 1063.5 2563.2 1567.2 1790.5 1281.2 3535.7 4567.8 3027.7 2844.3 3850.6 6013.0 3418.3 3504.2 3142.7 2924.3 2235.3 5420.6 3683.5 5561.4 3680.3 3142.1 2276.7 4963.3 6162.5 4765.3 2251.9 4262.2 8647.1 3224.4 5009.5 4698.1 5817.4 4197.2 2100.2 5478.2 7877.0 1959.5 6027.1 4520.5 3281.1 3993.8 3909.8 4288.1 3200.3 6205.4 3467.9 7403.5 4567.2 4224.9 2885.2 3333.8 3746.8 4676.4 3425.9 6945.5 2678.6 3325.2 2101.9 4289.8 9110.0 3205.5 3707.5 10012.4 2932.1 2388.1 3534.7 2353.9 6119.2 3312.3 7992.5 5635.5 2580.9 8286.2 2335.3 519.6 1072.5 302.9 1155.2 949.1 1830.0 2371.9 1954.3 1477.4 1685.5 2173.6 2280.0 1986.3 148.5 1335.8 859.0 1700.9 1707.8 3337.5 1226.9 1244.9 1206.6 1768.4 1197.9 1253.8 1261.6 1218.6 1264.1 1265.4 1245.4 1281.2 118.0 814.1 1488.0 8.1 1824.1 43.2 5841.9 11.0 675.6 83.2 1696.6 859.5 428.3 2093.2 1039.5 176.6 50.1 3419.1 1523.2 487.4 545.9 1846.4 75.5 269.9 496.3 1390.0 963.5 1971.9 5.5 3041.8 6575.5 973.4 375.1 305.1 937.3 67.5 2470.1 3241.0 2716.5 42.1 6.3 2545.9 2.0 3330.0 46.3 229.6 4400.2 1201.6 30.2 7.5 3519.0 296.5 3137.0 6.0 10.1 2490.2 2021.5 1873.5 547.9 6309.4 1840.9 1036.8 504.2 121.4 1183.3 2746.2 689.9 611.9 701.6 1140.4 63.9 3414.9 1379.0 53.7 3448.3 5768.6 RPS19BP1 "FLJ21770, MGC52010" ENSG00000187051 "Ribosomal protein S19 binding protein 1" Q86WX3 22 39529093-39532761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042874 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" Nucleoplasm "HPA042874: AB_10793988" "unprognostic (2.44e-1)" "unprognostic (1.67e-1)" "unprognostic (7.79e-2)" "unprognostic (5.07e-3)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.65e-1)" "unprognostic (5.68e-2)" "unprognostic (8.31e-2)" "unprognostic (7.00e-2)" "unprognostic (6.73e-2)" "unprognostic (1.04e-1)" "unprognostic (6.11e-2)" "unprognostic (1.65e-1)" "unprognostic (2.34e-1)" "unprognostic (4.32e-2)" 98.5 123.0 122.2 43.1 124.5 61.7 94.6 126.7 159.0 73.5 115.9 117.1 43.5 65.5 31.5 94.2 65.6 19.3 114.6 121.2 119.7 123.1 158.5 80.4 48.0 126.5 124.2 68.9 109.6 47.1 66.5 30.2 123.7 108.1 19.2 23.9 94.4 42.8 104.7 80.0 78.3 19.7 124.8 100.5 101.5 65.8 128.4 40.5 96.7 45.4 34.6 99.9 73.7 123.9 94.8 117.6 54.5 80.4 60.7 39.7 110.8 102.0 87.3 92.5 74.0 131.1 62.1 118.9 107.4 64.5 74.8 73.8 87.8 111.3 32.2 163.8 261.5 110.0 105.5 118.0 88.2 166.8 142.3 60.1 83.1 80.3 96.8 49.4 64.9 87.6 128.0 83.8 61.0 108.0 80.6 164.1 95.1 210.9 209.5 127.3 70.0 182.0 99.7 95.8 121.2 66.9 85.8 137.3 203.1 33.6 98.8 134.8 74.0 77.5 168.8 85.7 141.7 140.3 145.4 188.4 103.3 116.8 183.1 126.8 147.4 187.3 133.0 141.6 123.5 159.7 135.1 140.6 122.4 173.9 129.9 132.8 168.7 128.9 119.4 193.1 165.1 138.3 122.2 124.5 126.7 159.0 121.2 119.7 126.5 124.2 123.7 124.8 128.4 123.9 113.6 44.8 51.4 13.1 109.5 137.1 94.3 124.3 84.2 98.0 178.6 205.7 73.8 105.8 83.0 97.5 52.1 152.9 114.7 205.5 217.2 174.9 23.6 68.6 69.8 121.0 142.6 83.5 8.7 192.2 231.9 92.0 76.0 81.6 69.8 62.0 116.0 184.8 204.3 35.3 10.9 207.5 130.2 116.4 233.3 40.3 137.0 110.8 108.5 8.4 147.8 139.1 162.7 5.5 18.7 233.5 202.2 126.0 193.3 206.8 274.9 362.2 54.0 103.7 78.9 74.4 100.9 61.6 138.0 87.6 147.9 131.6 115.2 103.1 165.9 132.4 RPS25 S25 ENSG00000118181 "Ribosomal protein S25" P62851 11 119015712-119018691 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031801, HPA078683" Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 150000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA031801: AB_10610419, HPA078683: " "unprognostic (1.60e-2)" "unprognostic (1.79e-1)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "unprognostic (8.32e-2)" "unprognostic (1.78e-2)" "unprognostic (1.55e-2)" "unprognostic (8.47e-2)" "unprognostic (5.23e-2)" "unprognostic (1.54e-2)" "unprognostic (2.36e-2)" "unprognostic (7.75e-3)" "prognostic unfavorable (3.00e-7)" "unprognostic (1.16e-1)" "unprognostic (1.07e-1)" "unprognostic (8.58e-2)" "unprognostic (2.20e-1)" 1030.5 759.2 703.6 735.1 728.1 1650.9 1487.8 698.3 1133.9 1226.7 679.4 957.6 596.1 817.3 1030.4 898.8 1058.0 573.8 771.4 675.6 730.6 879.4 830.1 672.8 1488.5 718.4 700.7 2254.5 1279.5 535.1 807.7 633.7 726.5 841.2 697.9 460.2 1068.5 606.0 1873.7 1107.6 773.8 578.5 748.0 889.7 875.5 283.5 722.1 1100.8 817.0 1278.8 1307.1 967.1 1005.4 749.3 960.2 646.9 1024.1 1063.6 1461.7 2371.7 994.2 1098.1 1159.2 724.7 635.6 1753.4 1580.0 2269.6 2031.5 853.8 782.5 1146.8 951.4 1305.8 852.5 1166.9 1278.1 3013.6 598.3 1718.0 1102.2 2122.0 924.8 2043.3 2460.8 647.0 1673.7 2154.5 1384.9 1739.3 1670.1 1288.7 1072.8 2396.1 2072.1 3727.7 1045.8 2204.6 1573.1 1447.7 1055.6 2743.5 1319.2 1228.3 830.4 1737.6 578.1 1850.5 1467.1 1175.2 1533.2 2972.9 1144.8 703.2 768.0 724.7 1198.9 1051.5 1232.2 2109.6 489.5 2563.2 806.5 997.3 1197.8 775.1 1976.3 1284.0 3220.0 3716.4 3654.3 2784.5 1945.5 3077.2 4507.9 3661.8 319.1 2123.4 1145.7 2384.0 2614.1 5186.2 703.6 728.1 698.3 1133.9 675.6 730.6 718.4 700.7 726.5 748.0 722.1 749.3 1697.5 810.9 1658.7 42.7 4105.7 3970.2 4377.8 2769.0 2486.4 284.5 3671.0 4464.2 177.0 2040.3 1857.3 932.5 114.7 3745.3 2579.2 1009.2 3273.2 1883.0 1859.4 927.5 1934.9 1947.4 1330.6 2078.2 25.4 3163.4 4115.0 1768.2 946.5 1319.1 2024.6 5691.5 2726.5 2709.6 2534.6 134.6 27.4 2786.8 895.2 3338.1 3963.7 2384.8 3824.6 2101.3 2186.0 30.9 4048.0 1305.0 2802.3 16.6 39.3 2301.3 2254.2 1713.3 1821.2 4000.4 2308.2 4494.5 909.9 475.7 1334.5 2501.7 2382.7 788.8 827.3 3140.7 4661.0 3656.0 3604.7 1427.9 2788.0 4153.7 RPS26 "eS26, S26" ENSG00000197728 "Ribosomal protein S26" P62854 12 56041351-56044697 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "ovarian cancer: 494.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043961, HPA055803" Uncertain Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA043961: AB_10963579, HPA055803: AB_2682927" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" "unprognostic (3.36e-1)" "unprognostic (9.58e-2)" "unprognostic (3.74e-1)" "unprognostic (7.84e-3)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.03e-1)" "unprognostic (2.06e-2)" "unprognostic (1.41e-1)" "unprognostic (4.40e-2)" "unprognostic (2.18e-1)" "unprognostic (7.99e-2)" 720.5 1265.1 387.6 271.7 388.8 395.5 690.2 382.8 480.4 707.7 384.0 731.2 177.1 569.7 410.7 875.4 724.0 123.3 713.0 380.9 416.6 701.8 926.6 521.9 512.9 396.3 399.7 1120.6 1170.2 274.3 476.7 251.6 389.9 627.3 403.3 69.8 592.3 335.9 778.2 857.3 744.1 307.2 383.4 832.0 717.5 208.8 394.0 616.8 544.1 390.6 715.6 734.3 698.0 389.2 639.2 763.3 853.6 319.5 1153.3 1696.4 852.0 633.4 929.5 1027.7 596.0 1182.7 281.7 1408.3 383.5 670.6 339.5 293.2 970.5 544.0 698.1 558.9 1552.8 743.9 482.1 719.0 1062.3 490.5 392.2 1036.9 1705.6 544.3 614.0 404.0 794.3 989.6 517.2 458.1 845.1 983.2 371.8 886.0 839.7 766.7 1710.8 496.7 254.8 884.3 871.4 634.9 318.2 552.4 245.8 542.2 372.2 252.1 479.4 538.6 260.8 255.0 524.3 328.0 518.0 369.3 810.2 770.9 284.0 969.2 334.4 334.8 394.8 262.5 650.7 410.2 723.2 872.3 841.4 711.8 508.4 720.3 898.4 863.6 154.8 607.5 373.0 643.6 963.7 1264.1 387.6 388.8 382.8 480.4 380.9 416.6 396.3 399.7 389.9 383.4 394.0 389.2 1114.5 224.4 237.7 5.2 2483.4 1760.6 852.7 2533.9 3266.8 131.0 1968.1 2542.2 29.2 1425.5 985.7 430.4 62.6 1237.2 1377.0 1803.5 972.4 1031.5 85.4 862.0 876.0 992.0 860.5 1977.9 5.2 2625.0 2835.4 1006.2 1666.7 861.2 514.4 1242.7 1647.4 2125.4 1369.2 75.7 5.1 1406.6 732.4 1557.8 1925.7 57.3 295.4 1146.8 1462.1 6.5 754.7 706.4 563.4 6.6 7.1 1806.8 1756.4 221.5 2590.7 1221.2 2448.3 1503.0 557.4 193.1 309.0 719.1 935.9 305.9 304.0 4236.6 1814.2 1708.2 2103.6 1318.5 1411.0 1000.6 RPS27 "MPS-1, MPS1, S27" ENSG00000177954 "Ribosomal protein S27" P42677 1 153990762-153992155 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA066851 Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: AB_2685737" "prognostic favorable (9.69e-4)" "unprognostic (1.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.35e-1)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (8.62e-2)" "unprognostic (5.88e-3)" "unprognostic (2.05e-2)" "unprognostic (5.04e-2)" "unprognostic (2.55e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (2.44e-1)" "unprognostic (8.81e-2)" 5616.3 3455.2 3594.8 2840.3 3661.4 7200.5 8666.0 3567.1 5829.2 7430.2 3632.2 5066.8 1888.2 4501.2 4042.3 4706.9 5856.4 2273.3 3532.4 3573.6 3695.5 4491.5 3641.9 4076.2 7137.0 3672.3 3637.9 12404.9 7506.0 3141.5 3807.8 2215.5 3648.3 5395.9 3581.3 1411.8 4351.2 3444.9 4963.3 7568.0 5438.8 2777.4 3605.2 6878.7 5028.9 1668.1 3632.1 8478.3 4692.8 4124.9 9185.3 5497.1 5730.0 3661.3 3446.4 3986.5 5147.0 2805.0 11901.1 11649.6 3148.9 4096.1 9832.9 5421.0 4866.7 8059.8 3705.0 7817.4 3304.5 6009.8 1792.6 3390.5 4624.1 6847.5 4577.2 3804.0 5945.0 3090.0 5442.0 5323.3 7881.7 6945.8 3888.2 11426.5 13193.2 4334.0 7920.5 8011.4 4546.6 6426.6 3865.0 4112.2 5239.5 8711.2 7513.7 4328.1 6227.9 11540.0 5775.4 4735.7 3753.2 6114.5 5064.7 6938.6 2702.3 5977.7 2340.0 8120.1 7572.9 6970.2 4531.0 13542.1 2672.3 1841.0 3043.3 2963.9 4141.0 8191.3 9166.7 9585.2 3202.5 3805.3 2591.7 12942.7 11463.1 5536.5 28801.5 11225.6 34790.5 56947.7 43040.6 37135.0 13993.9 48738.8 53667.4 42304.0 2458.8 27662.5 10603.9 23115.6 32257.9 76381.9 3594.8 3661.4 3567.1 5829.2 3573.6 3695.5 3672.3 3637.9 3648.3 3605.2 3632.1 3661.3 3187.7 2201.9 3978.4 11.4 13562.6 12494.3 5398.2 7693.2 4868.2 411.9 6937.5 6570.1 939.8 5752.0 4175.1 2155.5 193.9 6037.3 9149.7 2192.5 4431.5 4142.9 2927.6 1809.2 4392.1 3779.0 3022.4 4789.2 5.4 10431.2 6808.0 4116.6 2102.4 2597.5 4306.7 4628.6 6451.6 8222.0 4303.1 191.8 6.0 6849.8 1953.1 9173.5 14035.0 10184.0 7097.1 4890.7 5914.2 5.6 9465.8 1961.9 9527.4 3.0 6.8 6134.0 5941.1 3543.1 3703.6 4365.2 6412.1 6526.1 1955.9 646.0 2734.7 5847.6 4188.0 1563.3 1638.3 4859.8 14322.5 6382.1 11013.6 1757.5 6839.1 4530.7 RPS27A "S27A, Uba80, UBCEP80" ENSG00000143947 "Ribosomal protein S27a" P62979 2 55231903-55235853 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033319, HPA041344, HPA049132, HPA054087" Supported Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA Yes 230000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "CAB033319: AB_793618, HPA041344: AB_2677422, HPA049132: AB_2680646, HPA054087: AB_2682373" "unprognostic (7.32e-2)" "unprognostic (1.41e-2)" "unprognostic (1.11e-1)" "unprognostic (3.20e-3)" "unprognostic (2.16e-1)" "unprognostic (9.75e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (2.46e-1)" "unprognostic (6.89e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.09e-1)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (3.60e-1)" 1440.7 1208.5 1115.0 1077.7 1151.0 2567.0 2511.6 1098.2 1883.7 2166.1 1099.2 1563.5 823.5 1450.9 1105.1 1698.4 1726.7 572.2 943.7 1085.1 1131.6 1254.8 1162.3 1097.1 1955.6 1133.6 1117.0 3146.7 2043.5 730.2 1057.5 872.9 1131.4 1430.2 1045.0 631.9 1387.4 917.9 1089.6 1767.3 1328.6 814.7 1172.6 1719.2 1478.2 405.9 1150.4 1520.4 1201.6 793.7 1774.4 1506.3 1694.7 1157.1 2384.4 1092.2 1412.2 1842.3 1892.6 3200.3 2412.6 1824.5 1779.4 1692.3 1069.1 2073.7 1987.4 3081.3 2833.2 1698.5 1115.0 1784.3 2061.7 2465.1 1981.0 2899.1 2419.0 2693.9 1088.0 2758.1 2705.9 3674.4 1605.2 3166.1 4213.4 1280.5 3401.6 3015.5 2415.9 1959.5 2469.0 2228.9 1937.3 1509.9 2307.6 4328.7 2831.1 2690.2 1710.6 2086.4 3051.2 3173.8 1994.3 1817.4 1546.0 1319.2 1064.4 4071.8 3843.7 2065.9 1811.0 3411.1 2108.9 1351.7 2395.8 1318.7 3006.7 2322.2 1881.5 1867.9 1923.5 3226.7 1392.6 1301.5 1656.9 637.7 2924.2 1530.8 4268.2 4727.8 4504.3 3592.2 2219.0 4232.8 5675.0 4744.3 351.6 3178.7 1388.8 3292.5 3058.2 8225.2 1115.0 1151.0 1098.2 1883.7 1085.1 1131.6 1133.6 1117.0 1131.4 1172.6 1150.4 1157.1 3051.9 1272.4 2321.3 39.8 7158.8 8321.0 8963.0 6850.9 5010.5 446.4 8189.8 10987.6 438.8 3029.7 3486.3 1397.8 214.8 5340.9 5465.1 1499.3 4055.8 3640.9 1050.2 1695.4 3081.0 3385.0 2057.4 3362.1 45.8 7348.0 6754.1 3043.5 1762.0 1917.3 3014.6 3565.0 3729.5 3181.0 3498.7 218.7 47.8 3995.4 2199.2 5051.0 6045.7 1576.9 5081.5 3382.7 3639.2 59.0 6346.8 2229.4 5579.8 29.1 61.0 5045.3 3396.0 2881.2 3458.4 8189.2 3670.3 5961.1 1726.4 760.9 1643.5 5220.3 4020.2 1047.7 863.4 5750.5 8931.2 5390.3 6365.7 3721.9 4717.6 7980.9 RPS27AP5 ENSG00000231767 "Ribosomal protein S27a pseudogene 5" 1 192716132-192716653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "ovarian cancer: 16.3" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "NB-4: 4.6;SK-MEL-30: 4.2;THP-1: 4.7" "HPA041344, HPA049132, HPA054087" Uncertain Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA041344: AB_2677422, HPA049132: AB_2680646, HPA054087: AB_2682373" "unprognostic (2.56e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-2)" "unprognostic (8.64e-2)" "unprognostic (3.78e-1)" "unprognostic (5.09e-2)" "unprognostic (7.80e-3)" "prognostic favorable (5.72e-4)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.48e-4)" "unprognostic (3.07e-2)" "unprognostic (6.43e-2)" "unprognostic (5.80e-2)" "unprognostic (7.99e-2)" "unprognostic (2.58e-2)" "unprognostic (2.10e-2)" "unprognostic (3.62e-2)" 0.2 0.3 0.2 0.8 0.2 0.7 0.5 0.2 0.6 0.2 0.2 0.2 0.8 0.5 0.0 0.2 0.2 0.1 0.2 0.3 0.2 0.3 0.1 0.1 1.1 0.2 0.3 0.7 0.0 0.0 0.2 0.3 0.2 0.0 0.3 1.0 0.1 1.1 0.1 0.5 0.0 0.2 0.5 0.3 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.3 1.0 0.4 0.2 0.6 0.3 0.0 2.5 0.1 0.5 0.0 0.3 0.0 0.7 0.2 2.5 0.0 0.2 1.0 0.1 0.3 0.0 0.9 0.5 0.4 0.4 1.9 0.2 0.7 1.3 0.3 0.4 0.2 0.0 0.1 0.2 0.2 0.1 0.7 0.0 0.5 0.9 4.6 1.1 0.1 0.2 1.0 0.3 0.6 0.3 1.3 0.8 1.6 0.2 1.5 4.2 0.1 1.0 4.7 0.5 0.6 1.2 0.8 2.4 1.5 1.1 0.9 0.8 0.7 0.1 1.2 0.9 0.5 2.0 1.3 2.8 4.2 3.5 2.2 1.8 3.8 4.4 4.5 0.3 3.0 1.0 1.6 2.5 5.6 0.2 0.2 0.2 0.6 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 RPS27L ENSG00000185088 "Ribosomal protein S27 like" Q71UM5 15 63125872-63158021 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 2535.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA066851 Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: AB_2685737" "unprognostic (4.62e-2)" "unprognostic (5.81e-2)" "unprognostic (1.38e-1)" "prognostic favorable (9.08e-6)" "unprognostic (1.75e-1)" "unprognostic (7.24e-2)" "unprognostic (1.42e-3)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (1.80e-1)" "unprognostic (2.19e-3)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (5.31e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-3)" "unprognostic (5.10e-3)" 142.2 242.4 78.6 71.3 80.6 73.2 127.1 81.5 113.1 124.7 102.5 190.8 157.4 108.4 157.9 70.8 117.9 94.8 181.0 78.1 84.2 194.5 266.0 109.4 83.5 82.9 81.7 95.9 247.4 94.0 88.6 69.3 84.5 156.2 178.0 31.8 164.7 106.7 190.1 75.9 161.4 80.7 86.0 103.2 174.7 38.1 81.4 86.3 106.5 97.7 68.2 149.2 94.1 90.0 140.4 383.0 340.4 92.9 486.4 571.3 341.3 432.1 306.0 93.8 225.3 71.1 190.0 130.8 150.9 415.9 166.0 52.9 116.5 212.9 155.7 97.8 157.5 108.3 329.1 512.7 558.7 86.8 287.0 452.1 279.0 211.2 158.4 701.2 535.2 81.2 101.6 127.7 785.1 194.1 112.4 134.9 101.0 178.0 112.6 86.9 163.1 149.5 266.7 278.8 49.2 74.7 157.6 65.8 326.2 677.8 145.4 199.1 571.1 490.6 463.8 106.7 195.3 142.3 132.3 117.5 518.5 235.6 453.8 263.8 132.5 164.6 99.4 145.2 125.2 132.0 149.9 118.1 122.0 105.2 116.9 119.4 44.3 110.9 198.2 121.3 305.2 166.0 78.6 80.6 81.5 113.1 78.1 84.2 82.9 81.7 84.5 86.0 81.4 90.0 210.9 96.1 198.6 9.4 255.9 255.4 262.6 424.8 230.5 33.4 361.3 429.1 349.0 511.9 424.6 410.1 47.9 300.1 144.9 694.7 903.9 802.7 60.9 202.3 185.3 245.8 285.4 184.5 12.6 782.4 1269.2 269.2 327.8 155.5 302.6 250.8 302.0 994.8 542.1 13.5 15.6 742.3 520.8 372.1 358.1 34.4 314.7 270.3 466.0 17.8 1049.6 184.8 221.4 16.1 18.5 1019.3 745.5 297.5 495.5 324.6 1513.1 2535.3 330.9 75.2 263.0 180.5 742.6 144.7 82.1 183.6 247.6 235.2 224.7 214.3 732.5 215.2 RPS3A "MFTL, S3A" ENSG00000145425 "Ribosomal protein S3A" P61247 4 151099624-151104642 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Differentiation "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047100, HPA053454" Approved Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" No No 300000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA047100: AB_2679931, HPA053454: AB_2682156" "unprognostic (6.24e-3)" "unprognostic (3.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.16e-1)" "unprognostic (1.79e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "unprognostic (1.01e-1)" "unprognostic (6.41e-2)" "unprognostic (1.27e-1)" "unprognostic (6.81e-3)" "unprognostic (2.36e-1)" "unprognostic (1.96e-1)" "unprognostic (2.00e-1)" "unprognostic (3.39e-1)" 2233.9 1361.3 1032.4 1357.8 1063.0 4321.5 4603.8 1034.9 1672.3 3236.5 1041.5 1964.3 1314.5 1964.8 2303.4 2250.6 2307.9 1186.8 1430.3 992.0 1052.4 1657.2 1371.0 1471.0 3341.7 1038.8 1025.1 4877.7 3514.8 1107.6 1325.8 1372.7 1059.4 1982.7 1778.1 861.8 2107.7 1322.9 1967.9 2992.3 1848.5 1337.8 1102.5 2038.6 1898.7 586.2 1056.2 2991.3 1965.5 1499.1 2764.4 1969.9 2486.8 1089.1 2090.9 1501.8 2780.1 2751.6 3524.5 6867.8 2849.1 2150.7 3334.5 3006.4 1848.2 2933.6 2944.4 9381.3 1048.4 2383.2 1050.5 1339.3 2877.1 3624.3 2840.5 2075.6 2762.0 2023.6 1589.8 3421.2 4067.8 4855.0 1999.1 5125.5 7353.9 1849.5 4874.5 4195.4 3639.4 3417.8 3320.0 4722.3 3632.8 3124.8 5289.7 5604.8 2624.1 3296.7 1147.0 3798.0 2719.3 3175.4 3505.2 2487.1 2668.0 2635.2 971.4 3495.1 5019.9 1954.5 2341.0 5780.5 2212.2 1451.6 1915.8 1618.1 2424.7 3626.8 6367.6 5820.6 1863.4 3508.9 1758.5 1918.8 3362.4 977.5 3828.9 2626.4 6462.8 7155.1 6390.5 5052.0 5393.2 6165.0 8750.8 7174.2 495.2 5199.2 2256.0 6377.8 5103.3 18540.3 1032.4 1063.0 1034.9 1672.3 992.0 1052.4 1038.8 1025.1 1059.4 1102.5 1056.2 1089.1 2387.5 971.2 1605.1 15.0 5574.2 6158.3 8280.0 5535.6 4255.3 412.4 6080.4 8681.6 381.3 2194.8 2530.5 825.8 120.9 4538.4 4799.4 1188.9 4284.8 2316.3 1754.6 1570.1 3613.3 2564.2 2154.3 3366.6 17.8 3732.2 7502.1 2388.6 1599.9 1895.7 1468.6 3424.3 2653.9 1441.0 3403.7 163.2 18.6 4137.0 1454.6 4309.4 5658.7 4012.5 4428.4 3332.7 3260.3 20.6 5502.6 1760.6 4551.0 23.6 22.4 2788.3 3029.1 2592.3 2412.5 6111.5 2682.0 5073.3 1084.8 593.9 1768.4 4410.8 3918.5 834.4 820.8 5042.0 6756.0 4591.7 4520.4 4186.2 5049.9 7641.8 RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 236.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 21.1 18.8 6.9 33.7 10.2 16.2 14.8 12.7 12.8 16.1 8.5 32.8 24.1 17.5 8.5 18.7 15.1 26.9 21.1 8.7 9.4 19.5 45.0 32.3 31.3 8.4 10.0 10.6 17.2 59.4 5.9 19.5 8.5 19.9 31.8 15.7 13.2 18.0 51.8 15.0 27.6 27.8 8.7 29.2 21.1 5.5 10.6 32.9 21.2 40.3 32.6 34.2 8.5 8.0 44.9 77.0 28.4 14.8 27.1 47.3 8.6 38.0 57.4 27.8 37.7 87.7 56.2 29.3 12.8 40.0 40.5 30.9 32.8 32.2 51.1 24.8 26.1 34.6 46.2 236.8 27.7 67.8 34.2 30.3 25.1 43.5 54.4 24.3 101.9 30.4 23.1 81.0 29.4 21.2 44.2 20.7 20.6 57.8 45.9 23.3 60.0 33.8 23.9 36.9 13.1 12.8 51.1 15.3 54.4 35.3 0.1 20.0 57.3 30.1 20.8 96.3 21.7 64.3 42.1 32.1 56.9 33.1 72.6 11.9 3.8 7.9 4.7 5.3 8.3 2.4 5.4 5.2 5.6 3.2 3.7 4.5 5.8 6.6 6.0 6.7 2.9 2.2 6.9 10.2 12.7 12.8 8.7 9.4 8.4 10.0 8.5 8.7 10.6 8.0 60.6 44.8 67.5 31.6 34.8 54.4 37.0 21.2 10.2 37.8 20.4 10.8 22.9 34.3 41.1 16.5 22.9 4.0 70.0 63.5 3.9 26.3 0.4 10.8 24.0 61.1 25.0 19.1 142.2 30.5 6.7 31.6 24.5 26.1 44.3 8.3 34.6 65.4 22.6 13.5 108.4 59.1 28.5 40.8 104.3 1.5 13.1 62.6 37.4 126.5 53.7 27.5 46.4 116.6 27.0 37.4 57.9 21.1 25.5 56.6 33.5 25.1 23.3 9.7 19.7 41.5 21.3 6.4 8.7 13.8 55.5 3.6 66.0 14.2 61.1 63.8 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84188199 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.3;Inhibitory neurons: 70.7;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.1;PC-3: 7.9;RH-30: 9.9;SH-SY5Y: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.4 2.0 2.6 0.5 3.1 0.1 1.7 3.2 3.0 2.0 2.6 2.9 1.2 1.7 3.1 0.8 2.2 1.1 0.6 2.7 3.4 5.7 0.6 0.6 0.2 2.7 2.4 2.6 0.9 7.0 5.8 0.3 2.2 2.8 2.3 7.0 1.7 2.7 1.6 2.0 1.3 1.0 1.5 0.4 1.7 1.5 2.4 1.0 8.1 0.4 0.3 1.3 1.4 2.0 0.0 2.4 2.6 0.0 2.4 2.2 0.0 5.2 2.7 2.3 1.9 1.9 2.0 0.0 0.0 2.6 0.0 0.1 6.4 4.6 5.1 0.0 3.5 0.0 0.1 0.0 2.7 0.0 0.0 1.4 0.0 0.0 2.4 3.0 0.6 0.0 0.0 0.1 2.0 0.0 1.1 0.1 8.1 0.0 7.9 0.0 9.9 0.0 0.5 5.4 0.0 9.4 0.0 3.4 0.0 3.8 1.4 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.0 2.6 3.1 3.2 3.0 2.7 3.4 2.7 2.4 2.2 1.5 2.4 2.0 0.3 9.6 2.7 6.2 0.7 0.3 5.3 0.3 3.4 21.1 3.6 3.4 2.6 12.8 1.9 18.4 25.0 2.6 0.1 6.7 1.9 0.5 0.7 1.9 1.2 1.2 25.0 2.7 75.3 1.2 0.7 2.2 2.0 0.9 0.0 21.8 1.1 1.3 0.2 1.7 70.7 3.6 0.0 0.0 0.0 0.4 4.4 0.5 0.0 3.7 0.1 2.1 1.0 31.2 5.8 1.3 3.4 6.0 0.0 9.2 1.8 4.3 3.7 18.2 0.0 4.9 1.5 8.4 6.2 2.5 0.4 2.3 0.9 2.0 6.5 5.2 RPUSD1 "C16orf40, MGC19600, RLUCL" ENSG00000007376 "RNA pseudouridine synthase domain containing 1" Q9UJJ7 16 784974-788397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041144, HPA041938" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cell Junctions, Cytosol" "HPA041144: AB_10794265, HPA041938: AB_10795601" "unprognostic (1.51e-2)" "unprognostic (1.26e-3)" "unprognostic (2.03e-1)" "unprognostic (4.01e-1)" "unprognostic (2.99e-1)" "unprognostic (9.05e-3)" "unprognostic (1.07e-3)" "unprognostic (3.45e-2)" "unprognostic (1.08e-1)" "unprognostic (3.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (6.25e-2)" "unprognostic (8.07e-3)" "unprognostic (5.44e-2)" "unprognostic (2.95e-1)" "unprognostic (1.41e-1)" 11.8 12.9 12.3 9.7 11.9 13.5 12.0 11.2 21.1 11.0 6.8 14.9 9.8 13.1 3.1 18.7 10.6 4.7 12.0 12.5 10.0 13.0 15.3 9.5 11.3 12.9 10.7 9.2 16.1 4.5 11.2 4.2 10.9 14.6 2.5 2.2 15.2 5.1 11.2 18.1 15.6 3.6 9.7 21.9 17.0 7.2 12.4 8.3 11.0 3.1 5.3 13.1 11.8 11.6 28.2 32.5 7.8 35.7 6.8 7.9 36.2 22.9 13.0 29.4 21.3 76.4 25.8 38.9 24.3 11.1 20.6 47.2 18.1 23.1 5.3 35.7 74.0 19.2 52.1 28.0 10.9 35.8 31.1 11.7 21.9 25.4 6.7 8.7 20.4 22.6 45.7 17.1 10.2 89.2 44.8 37.4 40.0 13.0 55.4 79.0 21.0 80.5 10.9 17.0 40.8 29.4 26.4 42.7 26.1 4.6 22.0 43.9 23.3 29.1 37.9 30.9 33.6 27.2 29.6 45.7 14.1 27.8 24.5 16.5 14.8 13.7 12.7 13.7 12.6 10.2 10.7 14.1 17.0 12.0 10.7 11.1 9.2 13.4 13.6 15.8 14.8 13.1 12.3 11.9 11.2 21.1 12.5 10.0 12.9 10.7 10.9 9.7 12.4 11.6 9.4 3.2 3.3 3.6 12.9 15.9 3.5 13.2 10.8 42.0 12.8 13.3 4.4 5.7 5.2 9.2 2.1 20.5 13.7 23.0 7.9 19.5 0.4 4.7 7.1 8.1 13.2 6.3 6.0 26.9 25.7 6.8 17.9 8.2 0.0 10.9 9.3 5.1 19.6 1.7 4.2 11.5 10.2 5.7 7.0 1.8 6.8 9.0 14.2 1.9 19.2 11.1 23.7 1.5 3.5 29.9 16.6 6.4 19.5 6.3 21.1 10.2 3.4 3.8 13.1 3.6 9.4 3.6 11.4 11.5 16.8 14.6 11.9 13.3 20.7 5.0 RRAD "RAD, REM3" ENSG00000166592 "RRAD, Ras related glycolysis inhibitor and calcium channel regulator" P55042 16 66921679-66925536 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 305.8;skeletal muscle: 769.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 302.0;Endometrial ciliated cells: 477.6;Glandular and luminal cells: 245.5;Respiratory ciliated cells: 214.9;Skeletal myocytes: 179.2;Smooth muscle cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HDLM-2: 194.2;U-87 MG: 51.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041755 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA041755: AB_2677655" "unprognostic (1.40e-2)" "unprognostic (2.78e-2)" "unprognostic (9.77e-2)" "unprognostic (3.84e-2)" "unprognostic (1.36e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.06e-3)" "unprognostic (3.46e-2)" "unprognostic (3.33e-2)" "unprognostic (2.04e-2)" "unprognostic (4.80e-3)" 56.5 18.1 4.1 5.5 6.4 4.7 24.4 16.8 14.6 34.6 12.0 16.3 3.4 21.0 1.7 101.2 35.2 11.9 305.8 5.0 5.3 45.0 5.1 52.3 4.0 4.2 6.0 18.8 2.5 1.7 14.4 32.6 4.2 18.4 1.1 2.5 29.4 3.5 769.7 19.9 10.9 6.3 4.9 2.8 13.9 6.7 5.6 1.7 13.7 28.3 3.2 27.4 32.9 6.3 0.1 8.5 0.2 0.1 0.0 0.8 0.3 4.9 0.5 0.8 4.2 2.2 5.9 0.2 4.8 0.3 1.5 0.4 0.2 0.3 0.7 194.2 0.3 0.0 0.3 2.1 8.0 0.0 0.6 2.3 0.9 14.3 0.2 3.3 0.0 0.1 0.2 3.8 0.6 0.2 0.0 0.5 0.7 0.0 0.3 0.6 0.2 0.0 0.9 0.1 0.3 0.6 4.5 0.0 0.0 0.7 0.0 0.5 0.0 0.4 0.5 0.3 0.4 6.2 0.2 0.5 51.9 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 6.4 16.8 14.6 5.0 5.3 4.2 6.0 4.2 4.9 5.6 6.3 17.0 70.5 150.0 3.3 33.6 9.4 3.7 11.3 4.0 21.4 10.7 15.9 302.0 0.0 18.9 68.0 10.4 4.1 22.5 9.7 23.5 47.4 1.6 477.6 36.7 18.1 10.7 0.0 0.8 3.2 8.2 39.4 10.7 245.5 34.2 26.4 0.7 0.0 1.4 1.7 1.0 7.8 14.2 1.9 36.2 0.7 0.6 24.6 23.2 1.9 0.6 2.4 0.0 0.5 0.6 55.3 5.0 5.3 59.5 30.7 3.4 11.3 214.9 3.2 111.7 179.2 232.6 1.7 5.2 148.1 10.1 5.6 12.4 0.5 6.9 2.6 RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 129.1;Distal tubular cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cell line enhanced" "Detected in many" "Karpas-707: 63.9;SCLC-21H: 33.1;U-266/70: 80.0;U-266/84: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Centrosome" "HPA068664: AB_2686016" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.53e-3)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.80e-4)" "unprognostic (3.75e-2)" "unprognostic (1.66e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.47e-8)" "unprognostic (8.41e-3)" "unprognostic (1.23e-1)" "unprognostic (9.46e-2)" "unprognostic (4.40e-2)" 9.8 9.1 14.0 2.3 18.9 11.6 8.2 31.8 16.1 9.4 17.9 4.0 1.7 1.5 6.9 13.8 13.7 3.6 38.4 15.9 13.9 26.5 4.4 7.0 2.8 16.4 12.2 1.6 6.4 22.7 11.4 3.2 17.2 6.1 1.8 21.8 52.2 2.8 84.5 6.7 2.0 2.1 21.5 4.8 1.7 6.9 14.8 5.5 28.1 60.3 2.5 5.8 6.2 23.8 0.1 1.7 4.4 3.3 0.4 0.0 0.3 0.0 0.0 0.5 0.9 0.1 0.1 0.0 1.5 0.0 22.6 0.1 24.5 0.1 0.0 0.0 12.1 5.8 0.1 0.1 1.8 16.9 19.0 0.4 1.5 0.0 0.1 0.0 0.0 16.9 0.5 63.9 0.1 1.8 8.2 8.4 3.6 0.0 1.8 16.8 23.1 0.2 5.8 0.6 33.1 1.8 0.6 2.2 28.8 1.3 0.7 13.2 0.0 1.8 2.8 11.5 3.0 80.0 39.8 0.0 6.1 12.5 1.9 2.6 0.6 1.4 0.0 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.3 3.3 0.1 2.4 0.3 0.0 0.1 14.0 18.9 31.8 16.1 15.9 13.9 16.4 12.2 17.2 21.5 14.8 23.8 1.4 9.6 16.7 5.2 3.7 16.2 17.0 5.8 4.0 21.7 17.4 9.7 129.1 17.2 13.9 14.7 31.3 0.6 4.7 0.1 117.4 20.2 25.6 10.4 2.5 4.8 1.2 5.0 17.6 16.9 1.5 10.0 1.1 15.0 4.5 2.9 2.5 9.7 51.9 47.1 20.6 0.5 42.7 25.8 9.2 15.5 3.1 23.2 39.2 3.7 10.4 29.6 0.0 13.0 17.2 8.1 0.0 4.1 8.0 28.4 0.0 18.6 19.4 16.3 0.0 11.8 7.0 21.7 30.3 32.4 22.6 0.7 3.9 0.2 0.2 30.2 RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 90.9;skeletal muscle: 38.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 26.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: AB_2680965, HPA074403: " "unprognostic (2.79e-1)" "unprognostic (7.65e-2)" "unprognostic (5.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.42e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.12e-8)" "unprognostic (2.64e-1)" "unprognostic (1.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.54e-5)" "unprognostic (2.58e-2)" "unprognostic (3.32e-1)" "unprognostic (4.81e-2)" "unprognostic (6.99e-3)" 8.1 10.2 2.6 9.2 3.4 90.9 5.6 1.1 7.6 5.6 2.4 4.9 6.0 7.4 3.6 8.5 7.3 7.2 11.4 3.2 2.7 6.8 5.7 6.7 6.7 4.3 4.4 6.1 16.0 9.3 10.2 4.3 4.1 6.3 3.8 3.4 8.3 4.0 38.5 10.3 4.7 6.0 0.2 7.6 6.3 10.9 3.7 4.7 5.5 9.7 6.1 9.3 5.7 4.6 38.9 50.8 13.2 28.6 10.0 11.6 28.9 24.2 14.4 24.2 18.7 55.6 35.0 42.3 30.4 15.1 21.6 48.7 36.3 28.0 16.3 23.1 44.2 32.8 19.5 43.6 16.5 51.7 41.5 12.2 38.6 59.9 54.6 27.0 13.7 23.5 47.7 27.4 14.0 50.8 35.0 33.0 57.0 20.4 34.0 38.1 18.0 42.1 16.8 21.4 17.7 37.9 19.2 18.1 24.1 10.4 43.7 26.5 18.2 16.1 27.9 36.5 76.4 55.7 52.7 48.6 23.2 64.9 17.9 0.4 11.2 6.9 2.7 13.6 3.3 3.9 1.6 2.2 6.2 4.2 2.5 2.8 26.7 1.9 16.9 5.0 1.2 6.0 2.6 3.4 1.1 7.6 3.2 2.7 4.3 4.4 4.1 0.2 3.7 4.6 8.8 35.3 31.1 5.9 18.5 23.5 14.2 5.1 25.0 5.8 12.7 9.9 11.6 7.2 21.5 14.7 41.7 5.2 7.7 10.6 0.0 8.7 7.2 17.1 10.6 10.6 21.5 7.2 15.1 8.7 7.5 13.5 27.0 20.1 41.7 12.9 3.9 8.9 11.5 5.0 9.5 13.8 4.1 12.5 7.1 4.8 3.7 30.3 7.2 2.8 12.3 1.9 3.1 5.0 4.4 8.5 6.4 2.6 31.8 17.1 3.7 6.8 24.6 12.7 0.0 19.4 6.7 10.6 20.6 22.7 19.6 9.2 11.0 13.5 11.5 13.6 RRP15 "CGI-115, KIAA0507" ENSG00000067533 "Ribosomal RNA processing 15 homolog" Q9Y3B9 1 218285293-218337983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024639 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Mitochondria" Yes No "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Mitochondria" "HPA024639: AB_1844368" "unprognostic (2.68e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (5.19e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (3.65e-3)" "unprognostic (2.54e-1)" "unprognostic (2.76e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-1)" "unprognostic (1.11e-2)" "unprognostic (3.23e-2)" 4.0 2.6 1.7 3.3 1.7 4.1 4.7 2.5 2.4 3.0 1.4 3.0 2.1 3.7 2.7 3.0 2.9 1.9 4.9 1.8 1.9 3.4 3.5 2.8 3.7 1.4 2.0 3.8 2.9 4.5 1.8 3.6 1.6 3.1 2.9 2.2 2.6 2.4 9.6 3.5 2.4 3.4 1.5 2.9 2.6 2.4 1.8 2.6 3.5 7.7 3.5 3.9 2.8 1.9 9.8 7.2 7.9 5.7 5.6 7.8 6.7 9.8 7.3 10.0 7.2 14.1 8.8 14.0 13.1 7.6 6.7 8.7 13.5 13.0 16.6 5.7 10.1 10.9 6.6 7.8 11.6 17.0 5.6 5.4 7.8 13.1 17.4 4.4 6.6 6.5 22.7 4.4 11.4 8.9 11.3 8.3 15.7 7.8 14.8 7.8 4.9 13.8 8.0 8.9 9.0 13.1 8.3 15.3 15.0 9.3 11.0 12.1 9.3 8.0 7.6 14.3 18.3 5.4 8.9 14.4 9.1 8.1 13.1 0.3 0.8 0.1 1.6 1.3 2.3 2.4 2.0 1.4 1.2 2.3 2.6 2.6 0.2 1.6 1.1 1.7 1.3 0.7 1.7 1.7 2.5 2.4 1.8 1.9 1.4 2.0 1.6 1.5 1.8 1.9 33.7 32.1 28.1 7.5 36.0 65.3 33.6 28.7 24.5 31.1 32.6 31.0 68.4 22.8 25.0 36.8 10.4 38.1 32.7 13.5 27.4 39.7 17.0 22.6 47.3 27.9 12.1 41.0 18.4 52.2 59.1 32.2 19.9 28.5 31.0 18.6 21.8 44.2 33.6 26.9 16.1 20.8 6.1 17.3 18.5 4.6 37.6 17.4 21.4 7.5 20.8 21.2 24.7 7.5 9.0 36.8 9.0 24.8 13.0 34.9 5.2 37.2 11.7 23.6 26.3 72.1 33.0 59.7 69.1 24.3 47.6 18.1 26.4 20.4 32.1 23.0 RRP1B "KIAA0179, Nnp1, PPP1R136, RRP1" ENSG00000160208 "Ribosomal RNA processing 1B" Q14684 21 43659560-43696079 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 131.3;Early spermatids: 213.2;Late spermatids: 222.8;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017893, HPA020324" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA017893: AB_1852274, HPA020324: AB_1852276" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (4.03e-1)" "unprognostic (1.32e-3)" "unprognostic (1.24e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-2)" "unprognostic (7.19e-2)" "unprognostic (1.98e-2)" "unprognostic (5.55e-3)" "unprognostic (1.08e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.95e-9)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (4.24e-2)" 8.8 5.9 7.9 12.2 8.9 6.2 9.1 7.0 7.8 7.2 5.9 7.2 6.7 9.1 5.5 8.6 9.1 6.1 4.9 7.4 7.2 4.9 8.7 6.7 17.4 7.8 7.9 13.1 10.2 7.2 4.3 5.8 7.2 7.5 7.3 28.4 10.2 6.8 12.1 8.8 6.4 8.8 7.4 11.0 7.8 12.0 7.8 16.1 6.5 8.8 14.8 9.8 6.5 8.6 52.5 30.4 31.8 48.1 20.2 21.5 26.0 27.0 19.3 29.3 24.0 69.4 22.2 101.9 17.2 21.5 33.9 22.8 78.9 46.5 34.6 34.6 62.8 60.3 34.8 43.9 27.9 95.0 22.9 22.4 29.2 35.1 40.3 18.1 33.1 43.2 96.0 29.1 26.1 27.4 76.1 28.9 108.4 33.7 33.4 98.7 32.1 71.2 21.2 24.8 62.7 33.6 50.6 36.9 37.9 11.7 24.2 29.4 29.7 9.0 28.3 24.0 49.8 39.1 53.8 119.3 28.5 100.7 30.1 2.0 2.5 0.7 6.2 2.5 7.3 5.6 7.9 7.5 3.0 4.3 7.2 8.6 0.1 5.8 2.2 2.4 6.6 5.5 7.9 8.9 7.0 7.8 7.4 7.2 7.8 7.9 7.2 7.4 7.8 8.6 15.5 32.1 16.4 8.8 32.7 22.8 17.7 15.0 28.5 30.3 13.8 11.0 13.4 17.2 21.0 5.5 131.3 8.6 27.1 5.7 1.9 17.0 213.2 10.5 28.8 19.1 5.4 23.7 19.0 15.6 17.0 18.9 14.8 10.8 36.0 25.5 12.8 18.4 18.7 25.2 20.0 9.2 6.1 13.9 12.7 222.8 22.4 13.4 8.8 21.5 17.0 17.9 35.0 18.6 22.2 20.9 3.7 26.7 48.5 23.6 6.8 9.9 16.7 143.5 0.0 29.9 18.1 26.3 33.6 32.0 31.7 4.4 35.7 32.6 16.5 17.4 RRP7A "CGI-96, Rrp7" ENSG00000189306 "Ribosomal RNA processing 7 homolog A" Q9Y3A4 22 42508344-42519796 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001586, HPA046768" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA001586: AB_1078506, HPA046768: AB_2679796" "unprognostic (8.46e-2)" "unprognostic (3.30e-3)" "unprognostic (5.96e-2)" "unprognostic (3.21e-3)" "unprognostic (9.71e-3)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.21e-5)" "unprognostic (6.73e-2)" "unprognostic (3.00e-1)" "unprognostic (2.28e-1)" "unprognostic (2.41e-1)" "unprognostic (3.22e-2)" "unprognostic (9.53e-3)" "unprognostic (8.02e-2)" "unprognostic (2.12e-1)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" 14.0 16.5 15.8 9.8 18.0 12.3 15.4 14.3 17.0 13.9 11.6 13.9 6.2 13.7 28.2 18.7 13.9 4.7 15.6 16.4 14.1 22.3 18.4 13.0 14.2 15.0 15.3 17.3 14.5 11.1 11.2 6.6 15.5 22.3 6.1 5.2 15.6 7.5 13.8 15.7 13.8 6.4 13.1 18.4 15.0 12.8 14.6 10.3 13.6 5.2 10.2 14.8 14.0 15.7 23.9 34.6 21.1 24.7 13.7 8.8 35.9 21.0 13.7 27.0 22.8 47.4 14.3 41.4 10.6 15.5 13.4 29.3 25.4 28.1 11.1 11.2 50.3 21.8 26.4 23.6 11.2 57.1 19.4 12.1 16.4 35.6 17.7 10.5 15.6 21.6 30.7 12.1 15.9 51.5 54.8 23.0 17.9 20.5 25.5 88.9 19.9 17.6 13.7 31.5 9.8 8.4 14.8 50.5 20.7 8.9 18.2 23.9 12.4 22.9 25.1 16.4 21.1 18.5 16.0 48.8 18.2 20.3 31.2 16.1 28.0 22.4 21.2 33.2 20.4 26.1 18.4 19.7 21.8 32.5 20.0 18.8 5.7 20.4 37.2 37.6 17.1 26.2 15.8 18.0 14.3 17.0 16.4 14.1 15.0 15.3 15.5 13.1 14.6 15.7 32.2 22.4 36.6 5.9 48.6 43.8 95.1 41.4 12.5 26.6 28.6 28.3 16.0 31.5 37.2 22.0 16.7 93.0 50.3 48.4 17.6 71.3 55.8 24.2 25.4 38.6 26.4 64.6 7.5 27.2 133.8 31.0 34.7 28.8 47.5 46.3 37.5 32.6 94.8 26.9 6.8 39.8 28.5 43.3 47.4 118.3 22.1 39.5 33.8 6.5 116.5 24.8 68.0 1.0 7.9 52.1 46.0 18.4 51.4 94.3 38.5 42.1 34.4 28.5 6.6 30.2 37.0 33.5 24.7 27.3 37.8 120.4 40.2 45.2 59.4 106.3 RRP8 "KIAA0409, NML" ENSG00000132275 "Ribosomal RNA processing 8" O43159 11 6595072-6603616 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038487, HPA057562" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli, Cytosol" "HPA038487: AB_10672518, HPA057562: AB_2683468" "unprognostic (9.01e-2)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-2)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (3.10e-7)" "unprognostic (4.64e-2)" "unprognostic (2.48e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.23e-2)" "unprognostic (3.81e-3)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.87e-2)" 10.8 10.2 10.9 5.8 10.6 18.4 10.5 10.6 14.9 12.7 9.3 21.8 6.7 11.0 9.8 11.4 10.5 3.4 15.4 10.0 9.9 13.3 21.5 9.2 8.6 10.3 10.7 9.3 10.0 5.3 8.2 6.1 10.4 15.8 6.5 7.6 7.4 8.8 9.5 12.6 10.3 6.2 10.9 14.2 12.1 10.7 10.6 6.8 10.6 4.1 8.4 16.8 11.1 12.1 12.3 12.0 4.7 6.1 9.6 8.3 6.7 6.2 7.7 14.0 13.1 12.4 14.1 17.1 6.0 5.9 10.3 12.1 13.6 10.9 14.7 8.3 19.5 8.1 14.0 14.3 11.0 14.8 10.8 7.1 14.0 6.7 12.1 9.2 14.7 8.0 16.3 9.7 11.2 15.2 14.5 22.0 11.6 21.4 10.7 12.8 3.8 3.9 13.4 9.7 7.2 8.4 8.9 18.0 10.7 7.7 9.8 12.9 7.6 13.2 6.1 13.0 12.2 10.8 10.5 16.7 11.2 14.8 8.7 26.3 10.0 10.4 11.5 10.7 11.2 9.1 11.3 10.7 13.0 11.9 11.0 11.7 3.9 13.6 11.8 9.9 11.9 9.0 10.9 10.6 10.6 14.9 10.0 9.9 10.3 10.7 10.4 10.9 10.6 12.1 17.0 22.4 15.0 37.2 19.6 23.2 18.5 13.3 14.2 17.3 14.1 11.7 20.7 8.6 14.7 9.2 14.6 23.5 20.7 12.2 11.7 19.0 7.4 13.7 22.8 16.4 7.2 37.7 45.0 15.9 21.2 15.5 21.4 14.0 17.7 14.7 12.5 23.5 18.9 3.3 32.6 16.2 12.2 9.4 13.4 13.6 13.1 13.1 8.8 21.5 18.4 14.2 22.6 27.2 34.6 22.7 18.2 9.8 15.2 15.8 13.7 29.8 10.3 30.5 0.0 15.3 20.0 23.7 18.0 18.3 27.1 20.0 17.7 25.2 17.3 15.0 RSBN1 "FLJ11220, ROSBIN" ENSG00000081019 "Round spermatid basic protein 1" Q5VWQ0 1 113761832-113812476 "Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042124, HPA049484" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Vesicles" "HPA042124: AB_10794644, HPA049484: AB_2680787" "unprognostic (3.26e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (3.66e-2)" "unprognostic (2.30e-2)" "unprognostic (5.06e-2)" "unprognostic (6.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.96e-1)" "unprognostic (1.51e-2)" "unprognostic (4.67e-2)" "unprognostic (1.43e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-3)" 6.4 6.0 4.6 7.7 4.7 34.4 8.2 12.7 6.1 7.9 2.8 8.4 6.2 10.3 6.5 7.3 7.9 6.4 5.2 4.2 5.3 8.0 6.4 7.5 10.6 3.1 3.7 14.2 11.0 11.0 5.1 6.6 3.2 7.9 8.6 13.7 6.8 6.9 8.0 7.5 7.5 7.0 3.9 9.2 6.8 10.7 4.3 12.3 9.0 7.9 10.5 6.4 5.5 5.2 14.6 4.1 13.7 8.2 8.0 9.2 6.6 5.1 10.9 10.1 10.5 4.9 4.3 12.7 7.9 6.3 4.6 6.2 9.8 6.2 16.4 12.3 7.1 9.6 4.4 5.6 6.0 18.1 9.9 7.0 6.7 8.6 8.2 8.6 8.1 14.0 14.7 7.7 7.5 14.9 14.7 10.8 11.6 4.6 6.9 26.3 13.4 6.6 6.0 6.2 13.8 11.0 9.7 9.4 8.7 6.8 4.5 12.1 9.7 9.0 9.7 13.5 8.3 10.3 8.2 15.9 9.3 10.9 15.4 53.3 14.5 25.6 29.1 11.7 29.3 32.2 31.2 27.2 12.8 33.1 31.9 26.2 29.0 25.4 13.4 27.3 30.6 12.6 4.6 4.7 12.7 6.1 4.2 5.3 3.1 3.7 3.2 3.9 4.3 5.2 37.4 35.3 20.1 16.0 52.7 74.7 39.2 26.9 45.5 90.0 35.0 46.7 21.5 24.3 29.6 25.8 66.7 26.3 68.0 55.5 19.6 22.3 25.6 26.2 39.4 38.9 49.4 37.5 34.3 26.0 24.1 41.5 17.9 28.8 36.1 23.4 32.5 18.7 19.2 97.6 34.2 58.5 28.5 26.3 37.7 9.0 50.4 25.7 40.9 30.9 35.0 56.7 62.8 33.7 34.6 21.2 54.0 49.7 34.7 44.3 40.2 17.2 27.8 106.5 39.5 43.8 54.9 96.8 37.0 34.3 65.1 31.5 84.8 24.2 52.7 37.8 RSKR "FLJ25006, SgK494" ENSG00000167524 "Ribosomal protein S6 kinase related" 17 28601827-28614197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.1;Extravillous trophoblasts: 2.4;Hofbauer cells: 4.1;Syncytiotrophoblasts: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in many" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.83e-1)" "unprognostic (9.42e-2)" "unprognostic (2.84e-2)" "unprognostic (2.30e-2)" "unprognostic (2.11e-1)" "unprognostic (2.06e-3)" "unprognostic (9.33e-3)" "unprognostic (2.63e-1)" "unprognostic (8.62e-4)" "unprognostic (2.09e-2)" "unprognostic (6.81e-2)" "unprognostic (3.45e-5)" "unprognostic (1.20e-7)" "unprognostic (2.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-3)" 0.2 0.5 1.2 0.8 1.2 1.6 0.2 1.4 1.7 0.4 1.2 0.2 0.3 0.3 0.1 0.1 0.4 0.0 0.2 1.1 1.2 0.9 0.2 0.2 0.3 1.3 1.2 0.5 0.1 0.1 0.4 0.3 1.4 0.3 0.3 5.8 0.1 0.1 0.5 0.7 0.3 0.1 1.1 0.4 0.2 1.1 1.3 0.4 0.3 0.1 0.3 0.3 0.2 1.5 0.4 0.5 0.6 0.8 0.2 0.1 0.2 0.0 0.0 0.6 0.2 0.9 0.1 1.2 0.1 0.0 0.4 0.6 0.8 0.1 0.6 0.3 0.6 1.0 0.4 0.4 0.0 0.2 0.8 0.0 0.4 0.3 0.4 0.1 0.2 1.2 0.6 0.2 0.1 1.3 0.4 1.0 1.2 1.2 0.1 0.8 2.2 0.7 0.5 1.3 0.4 0.4 0.4 0.1 0.9 0.9 0.5 0.5 0.4 0.3 0.8 0.7 0.5 0.6 0.4 0.6 0.4 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.4 1.7 1.1 1.2 1.3 1.2 1.4 1.1 1.3 1.5 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.8 0.2 0.0 0.0 0.0 RSL24D1 "C15orf15, HRP-L30-iso, L30, RPL24, RPL24L" ENSG00000137876 "Ribosomal L24 domain containing 1" Q9UHA3 15 55180806-55197049 "Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062724, HPA063392" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA062724: AB_2684850, HPA063392: AB_2685002" "unprognostic (3.40e-2)" "unprognostic (3.00e-1)" "unprognostic (3.83e-1)" "unprognostic (7.28e-2)" "unprognostic (3.80e-2)" "unprognostic (1.07e-3)" "unprognostic (6.71e-3)" "unprognostic (1.15e-1)" "unprognostic (6.56e-3)" "unprognostic (1.34e-1)" "unprognostic (6.19e-3)" "unprognostic (7.22e-2)" "unprognostic (1.13e-1)" "unprognostic (4.44e-1)" "unprognostic (4.54e-2)" "unprognostic (4.95e-1)" "unprognostic (2.41e-1)" 67.0 62.0 47.9 60.2 50.4 238.6 121.8 59.7 71.1 69.6 43.9 57.9 48.2 89.8 68.7 55.2 59.8 55.2 66.1 50.0 51.9 64.2 73.0 48.3 88.0 49.1 49.1 138.6 77.0 52.5 34.2 45.8 50.1 55.1 53.0 54.1 65.2 49.0 91.2 51.6 48.7 61.8 51.3 52.0 60.3 51.0 49.0 82.2 74.3 74.5 76.6 75.0 46.1 59.9 122.0 115.2 130.2 168.5 95.7 172.4 104.6 126.1 127.5 95.6 117.0 112.2 70.8 361.8 110.5 86.5 100.9 141.4 165.3 137.2 125.9 183.6 104.1 191.3 89.1 148.7 219.6 365.0 121.7 154.1 282.4 98.9 286.0 162.6 120.5 275.2 352.0 256.2 114.3 122.5 202.5 324.3 159.8 246.9 105.9 156.7 162.8 565.2 148.3 108.8 181.0 218.7 57.6 159.2 430.1 100.6 152.3 524.9 90.4 82.1 98.5 99.3 181.6 249.5 420.2 382.3 129.3 353.9 142.4 61.3 99.2 51.1 76.9 101.5 124.8 123.6 115.9 98.2 116.9 98.1 173.9 134.8 24.9 103.3 108.9 90.0 142.4 229.9 47.9 50.4 59.7 71.1 50.0 51.9 49.1 49.1 50.1 51.3 49.0 59.9 146.9 99.3 79.8 6.8 259.2 580.6 425.7 437.4 275.4 85.4 258.9 299.5 69.0 140.2 177.6 84.6 22.9 150.2 219.9 51.2 285.7 182.2 100.6 127.2 177.7 154.9 140.2 189.9 14.8 271.1 247.6 191.9 99.4 126.3 152.8 103.6 114.5 64.0 143.1 15.2 15.2 128.0 197.4 212.2 414.4 40.8 203.5 164.2 284.6 11.2 247.2 91.0 170.0 8.5 13.9 218.9 118.2 149.3 174.8 347.4 114.6 355.1 105.0 62.8 157.8 274.6 215.6 116.9 151.8 173.3 522.2 174.4 251.7 118.3 144.3 332.5 RSRC2 FLJ11021 ENSG00000111011 "Arginine and serine rich coiled-coil 2" Q7L4I2 12 122503454-122527000 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040070, HPA048183" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA040070: AB_10673430, HPA048183: AB_2680302" "unprognostic (4.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-2)" "unprognostic (1.44e-1)" "unprognostic (6.42e-3)" "unprognostic (6.90e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (2.74e-2)" "unprognostic (3.26e-1)" "unprognostic (3.19e-2)" "unprognostic (1.06e-2)" "unprognostic (2.23e-2)" "unprognostic (8.87e-2)" "unprognostic (4.84e-2)" "unprognostic (1.53e-2)" 12.6 12.2 11.5 11.0 11.4 65.7 13.2 17.6 18.4 14.6 11.3 13.9 8.6 14.1 12.5 17.4 12.3 13.6 13.1 11.3 15.3 16.3 11.4 13.8 16.8 12.1 13.7 16.4 13.8 8.0 14.5 13.3 11.7 12.7 12.0 17.1 12.6 9.5 28.5 12.7 12.5 8.8 7.7 11.6 10.8 14.0 11.8 13.2 15.4 16.1 10.7 14.0 15.0 14.0 21.4 24.8 23.2 9.5 18.4 11.2 16.9 38.8 12.0 16.0 8.7 35.5 8.6 24.4 32.0 13.3 9.7 13.3 25.9 10.8 15.7 22.8 23.9 42.1 32.0 38.3 10.1 37.0 24.8 14.5 12.3 13.6 23.2 20.1 11.6 10.7 27.8 14.6 14.1 16.3 26.8 27.8 19.6 17.8 19.6 19.6 20.9 15.9 21.1 39.8 18.4 16.7 29.6 10.0 22.0 23.1 15.9 13.4 18.1 16.5 20.3 18.4 21.7 16.7 42.8 39.5 9.8 21.6 9.4 27.5 17.7 25.4 17.2 14.7 14.3 28.3 15.3 13.9 18.0 33.4 19.3 15.4 18.7 18.3 22.2 17.0 22.4 12.3 11.5 11.4 17.6 18.4 11.3 15.3 12.1 13.7 11.7 7.7 11.8 14.0 176.8 86.6 102.0 44.7 208.7 202.3 376.1 94.0 118.4 114.3 155.6 146.0 103.3 104.4 107.1 93.8 79.2 149.1 219.3 193.5 195.6 109.3 247.3 223.6 218.6 141.7 156.3 143.1 39.1 97.2 183.8 169.3 89.7 238.0 216.5 127.5 84.9 113.7 94.3 149.7 39.9 185.7 101.7 87.6 184.9 107.1 119.9 139.0 126.3 35.6 107.0 132.9 133.9 34.2 49.6 107.3 171.0 105.7 134.2 219.0 110.1 132.7 128.5 131.0 124.9 194.8 176.7 229.2 165.3 116.0 187.0 280.1 210.3 107.6 154.8 287.1 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 73000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 43.5 44.5 33.3 39.0 36.0 31.4 51.2 37.5 40.8 37.7 35.6 56.1 93.9 43.9 43.7 49.4 46.5 32.6 45.8 33.5 38.1 75.9 75.2 36.3 45.6 36.7 37.0 45.6 45.8 73.0 39.8 45.5 39.1 45.9 73.8 44.1 47.2 47.4 71.1 76.9 79.1 56.0 38.3 43.7 48.4 32.0 36.3 72.9 41.5 63.6 87.9 53.9 39.2 40.2 116.1 101.9 125.0 94.3 106.8 79.1 99.3 98.8 118.5 154.6 145.9 133.2 45.9 28.5 64.6 116.1 95.2 76.7 144.7 143.5 198.6 144.3 144.8 81.4 83.0 122.1 73.4 192.4 71.2 78.3 93.7 153.3 147.8 85.1 141.3 78.5 98.2 78.7 114.3 96.4 82.5 66.4 71.7 133.4 91.7 126.0 134.7 147.1 106.0 99.0 128.3 71.1 107.2 68.5 129.2 130.6 75.5 73.8 107.3 84.8 124.8 74.7 96.5 54.4 46.6 102.1 87.8 85.6 113.4 112.5 135.3 89.2 93.0 151.3 104.4 143.5 96.6 97.4 161.4 150.4 114.8 99.1 13.2 125.7 118.7 90.4 131.7 156.3 33.3 36.0 37.5 40.8 33.5 38.1 36.7 37.0 39.1 38.3 36.3 40.2 32.0 32.1 33.4 15.3 40.3 60.5 54.9 84.9 47.8 51.6 35.4 27.6 35.8 47.1 60.6 35.0 20.9 112.6 43.0 74.8 66.5 108.4 4.8 46.3 28.6 45.4 46.7 36.4 22.4 95.6 87.9 35.8 45.9 53.8 42.6 50.5 41.0 58.3 85.4 52.2 19.6 62.2 116.0 47.4 45.9 10.8 35.1 43.2 30.2 25.3 80.0 66.9 34.0 28.6 35.1 106.5 62.1 47.8 36.0 64.3 178.2 146.9 48.2 56.9 26.3 35.4 43.0 67.0 65.1 52.7 76.0 97.8 34.1 59.3 61.3 73.8 RTL3 "FLJ38865, Mar3, Mart3, SIRH9, ZCCHC5, ZHC5" ENSG00000179300 "Retrotransposon Gag like 3" Q8N8U3 X 78656068-78659328 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 1.8;GAMG: 1.4;HBF TERT88: 2.4;hTEC/SVTERT24-B: 1.7;RH-30: 2.1;U-251 MG: 1.6" "Region enriched" "Detected in single" 9 "hippocampal formation: 2.8" "HPA051991, HPA053174, HPA075136" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA051991: AB_2681683, HPA053174: AB_2682069, HPA075136: AB_2686737" "unprognostic (3.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.69e-2)" "unprognostic (2.85e-1)" "unprognostic (4.00e-6)" "unprognostic (1.53e-2)" "unprognostic (3.64e-1)" "unprognostic (2.49e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 1.0 1.1 0.0 0.0 0.0 0.0 1.8 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.6 0.0 1.6 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RTL4 "FLJ46608, Mar4, Mart4, SIRH11, ZCCHC16" ENSG00000187823 "Retrotransposon Gag like 4" Q6ZR62 X 112454500-112457112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "testis cancer: 1.4;thyroid cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003272 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane, Cytosol" "HPA003272: AB_2257414" "unprognostic (9.86e-2)" "unprognostic (2.04e-4)" "unprognostic (6.35e-2)" "unprognostic (5.33e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.8 1.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 25000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: AB_10673290" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (9.74e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" 28.2 33.1 9.6 13.4 10.5 13.3 26.1 9.8 10.2 27.2 11.3 29.1 9.4 27.5 8.1 33.9 24.5 8.8 20.4 9.5 10.1 24.1 21.3 26.6 14.2 10.2 10.0 23.9 24.4 13.5 22.7 9.0 10.1 22.4 8.2 7.4 25.8 8.6 33.8 33.1 25.9 7.8 9.9 35.2 24.2 10.9 10.0 13.6 24.7 10.1 11.5 26.3 27.2 10.6 13.9 22.5 11.8 15.7 22.3 18.2 13.4 24.2 17.2 14.1 16.3 22.0 31.6 22.4 13.4 29.6 16.2 12.6 21.9 31.6 16.4 71.2 16.6 39.2 17.1 16.0 22.8 22.0 20.7 18.5 17.1 9.5 27.0 24.6 15.5 12.5 16.2 20.8 12.7 42.0 23.5 15.2 12.6 15.0 10.5 20.9 8.4 20.9 23.5 22.4 11.7 16.7 35.4 22.5 13.2 14.8 18.0 26.6 18.8 18.3 6.2 10.0 19.3 12.8 21.2 39.8 16.9 39.0 17.2 14.9 4.8 11.9 2.2 5.1 1.3 3.8 2.7 2.3 4.2 5.7 1.9 2.4 7.9 1.8 7.1 4.8 4.5 29.8 9.6 10.5 9.8 10.2 9.5 10.1 10.2 10.0 10.1 9.9 10.0 10.6 19.8 35.3 30.8 30.0 23.6 10.3 11.5 11.7 16.5 9.3 17.8 17.5 22.8 28.6 23.1 14.7 20.9 21.7 15.7 20.0 9.8 19.7 8.0 28.2 21.9 20.9 10.8 27.7 31.8 14.4 15.8 19.7 19.9 20.0 29.8 20.4 12.5 14.1 31.1 11.8 28.4 17.5 8.2 30.7 21.0 3.4 23.0 137.2 10.6 21.5 43.7 11.9 15.5 23.1 33.9 22.1 18.5 27.1 18.3 14.2 14.1 34.0 32.8 12.0 6.6 20.8 17.8 11.1 8.4 21.9 11.4 21.2 19.5 25.0 15.3 10.2 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.8;Cytotrophoblasts: 22.3;Extravillous trophoblasts: 21.0;Hofbauer cells: 14.8;Syncytiotrophoblasts: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: AB_1845580" "unprognostic (1.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.25e-2)" "unprognostic (4.22e-1)" "unprognostic (6.21e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (9.89e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.24e-2)" 27.1 31.8 19.6 20.0 18.9 21.5 28.8 12.0 21.3 45.4 14.2 29.6 31.3 43.2 20.7 26.5 38.2 23.0 28.5 19.9 19.7 29.5 57.9 25.0 19.8 17.0 16.0 49.6 56.8 46.2 48.4 25.7 18.5 39.1 19.1 22.4 64.8 34.2 9.4 26.9 30.3 25.6 13.8 22.3 39.5 21.4 17.0 18.0 42.0 9.8 15.6 31.8 31.4 17.0 28.6 37.2 22.7 39.7 51.7 34.3 42.3 33.4 56.6 25.5 30.2 11.3 49.1 24.5 69.4 49.8 32.9 39.0 22.9 31.0 11.8 35.8 23.0 24.8 20.6 28.8 74.8 29.4 28.6 41.7 33.1 33.7 68.5 50.2 24.9 38.4 37.3 40.9 25.3 53.9 13.7 19.8 17.8 41.8 24.1 31.1 34.2 74.8 29.3 17.6 24.8 38.2 25.2 65.3 52.8 21.5 56.6 42.9 22.0 44.3 24.7 28.7 22.1 59.0 37.0 18.8 56.7 44.7 62.5 3.1 5.7 7.6 7.8 8.4 7.2 6.7 8.2 7.8 9.7 6.3 7.9 7.0 0.9 9.4 8.1 8.9 9.4 7.2 19.6 18.9 12.0 21.3 19.9 19.7 17.0 16.0 18.5 13.8 17.0 17.0 5.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 21.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 22.3 0.4 0.0 0.0 0.0 RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993562-49015970 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 614.5;Late spermatids: 945.1;Respiratory ciliated cells: 253.6;Spermatocytes: 394.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012432, HPA042880, HPA067966" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA 53000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Centrosome "CAB012432: , HPA042880: AB_2678210, HPA067966: AB_2685933" "unprognostic (1.71e-1)" "unprognostic (9.06e-3)" "unprognostic (3.51e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (7.06e-3)" "unprognostic (6.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.13e-2)" "unprognostic (7.58e-2)" "unprognostic (2.81e-2)" "unprognostic (2.21e-2)" "unprognostic (7.61e-3)" "unprognostic (1.61e-1)" "unprognostic (2.58e-1)" 23.4 21.7 41.4 26.7 42.9 51.4 22.6 44.6 54.6 23.5 48.9 29.8 27.9 19.3 15.3 36.7 72.2 15.8 37.0 44.7 42.6 19.4 24.0 19.6 30.8 42.4 45.8 25.8 34.5 28.2 6.5 24.0 44.2 20.2 17.4 14.9 32.5 25.4 60.3 30.7 24.7 19.0 41.4 20.6 22.6 110.7 43.8 38.9 23.8 39.1 21.3 22.6 7.2 52.3 236.5 346.0 63.3 250.2 45.0 50.9 88.8 105.4 86.3 214.9 162.5 267.4 148.7 219.9 78.5 106.8 93.7 134.6 99.9 210.3 68.5 99.2 323.7 158.8 196.7 241.0 119.1 318.8 96.8 78.0 68.0 145.0 113.5 59.2 114.1 232.8 266.6 121.3 90.5 195.2 234.1 218.5 122.6 162.4 152.4 227.4 156.9 155.8 110.5 182.7 155.7 169.9 132.2 164.2 66.2 30.4 125.9 179.4 104.8 100.8 135.1 63.8 318.1 171.4 177.1 223.6 76.2 174.6 156.4 51.1 54.9 18.9 42.6 52.4 46.8 54.5 45.2 42.3 65.9 52.6 42.9 40.0 3.7 47.4 48.5 48.9 49.2 55.4 41.4 42.9 44.6 54.6 44.7 42.6 42.4 45.8 44.2 41.4 43.8 52.3 16.5 12.8 20.7 4.2 25.3 27.8 52.0 89.8 37.5 17.5 30.4 33.7 48.5 24.3 55.7 33.1 33.3 104.6 15.0 33.8 46.9 78.3 614.5 131.7 29.6 27.3 17.5 58.1 6.1 71.8 81.8 36.6 28.5 25.4 13.3 32.8 23.2 34.2 51.1 18.5 5.2 38.5 52.9 22.9 25.5 945.1 36.1 18.9 26.6 1.9 35.5 31.2 27.8 4.5 5.6 56.0 30.6 42.9 41.3 43.5 33.1 70.4 253.6 31.4 19.7 28.9 65.4 394.2 43.9 49.2 27.6 115.9 20.8 37.1 61.0 38.8 RYR1 "CCO, MHS, MHS1, PPP1R137, RYR" ENSG00000196218 "Ryanodine receptor 1" P21817 19 38433691-38587564 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 1618.9" "Cell type enhanced" "Detected in many" "Astrocytes: 29.4;Basal squamous epithelial cells: 22.8;Microglial cells: 49.6;Muller glia cells: 50.6;Skeletal myocytes: 41.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "intermediate monocyte: 1.8;myeloid DC: 2.9;non-classical monocyte: 3.8" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 3.8" "Cell line enhanced" "Detected in some" "A549: 7.7;HaCaT: 18.9;hTCEpi: 7.6;RH-30: 15.3;SiHa: 30.7;U-2 OS: 12.4" "Low region specificity" "Detected in single" HPA056416 Enhanced Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 46000 "Cluster 51: Monocytes - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Golgi apparatus, Vesicles" Cytosol "HPA056416: AB_2683121" "unprognostic (2.22e-3)" "unprognostic (1.91e-3)" "unprognostic (9.59e-2)" "unprognostic (5.34e-4)" "unprognostic (2.50e-1)" "unprognostic (6.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.20e-3)" "unprognostic (3.52e-1)" "unprognostic (2.35e-1)" "unprognostic (1.07e-5)" "unprognostic (1.13e-2)" "unprognostic (8.10e-2)" "unprognostic (6.62e-3)" "unprognostic (1.34e-1)" 1.4 2.4 10.3 1.6 8.0 0.3 2.1 8.5 9.3 2.1 1.0 1.2 0.5 0.7 1.3 17.2 1.7 1.1 0.9 7.5 20.5 1.9 0.4 2.6 2.1 8.6 9.7 0.9 0.4 1.9 1.5 1.8 7.7 3.8 0.3 10.6 14.0 1.4 1618.9 13.3 1.3 0.8 2.6 1.7 1.0 8.9 22.6 1.5 1.2 286.6 2.6 1.0 3.3 6.1 0.0 7.7 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 2.8 0.4 0.5 6.3 0.0 0.0 18.9 0.2 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.6 1.7 7.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.5 1.0 0.0 0.0 15.3 1.5 0.8 0.0 0.0 1.5 30.7 0.0 0.0 0.6 0.7 5.9 0.0 0.0 12.4 0.3 0.0 0.4 1.4 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.2 1.8 0.2 0.2 0.1 0.3 2.9 0.3 0.0 0.0 0.0 0.0 3.8 0.0 0.4 0.3 10.3 8.0 8.5 9.3 7.5 20.5 8.6 9.7 7.7 2.6 22.6 6.1 0.3 0.0 1.1 29.4 1.4 11.3 3.8 6.6 22.8 8.9 0.5 7.9 3.6 0.0 1.1 0.0 2.1 0.2 1.2 0.0 5.9 0.1 6.7 0.2 0.9 1.0 0.0 0.4 10.2 0.0 0.4 0.9 0.0 0.5 0.0 0.3 0.7 0.0 8.8 1.7 17.2 0.0 2.0 2.9 15.2 5.9 3.1 6.2 0.0 49.6 1.3 50.6 0.0 13.6 2.0 0.0 0.0 1.9 0.9 0.8 0.0 0.2 0.4 1.8 0.0 41.7 1.2 6.3 7.4 7.5 4.7 0.3 2.6 0.4 0.0 0.7 RYR2 "ARVC2, ARVD2, VTSIP" ENSG00000198626 "Ryanodine receptor 2" Q92736 1 237042184-237833988 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 132.0" "Group enriched" "Detected in many" 10 "Cardiomyocytes: 2180.6;Excitatory neurons: 1320.5;Inhibitory neurons: 790.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.7;HEK 293: 8.5;K-562: 2.3;NB-4: 2.7;NTERA-2: 3.1;U-937: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020028 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA020028: AB_1856528" "unprognostic (5.23e-3)" "unprognostic (2.15e-2)" "unprognostic (5.02e-4)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (1.45e-3)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (0.00e+0)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" 0.7 0.7 9.1 0.8 15.9 0.0 0.6 8.7 24.0 1.5 0.0 2.0 0.2 0.7 0.4 2.9 0.7 1.9 132.0 10.5 0.0 0.1 0.1 1.8 0.1 0.0 0.0 2.9 8.4 0.0 1.8 1.2 0.0 2.9 0.5 6.5 0.5 1.7 0.1 0.3 0.5 0.7 0.0 1.3 1.5 1.1 0.0 0.1 4.4 0.3 0.0 1.2 0.4 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.9 0.3 0.0 0.0 7.7 8.5 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 2.3 0.4 0.0 0.0 0.0 2.7 3.1 0.6 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 9.1 15.9 8.7 24.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.2 0.0 0.5 17.0 0.0 0.4 0.0 0.0 0.0 74.2 0.3 0.1 2180.6 0.0 1.3 1.8 10.4 0.1 0.1 0.0 0.0 0.0 21.1 0.2 3.4 10.6 3.5 0.0 1320.5 2.9 0.1 53.6 0.0 0.5 0.0 0.5 1.1 0.0 0.1 1.7 790.6 0.0 0.0 0.0 0.2 15.3 1.2 1.3 8.8 48.7 0.0 1.3 0.0 29.7 140.6 0.4 0.0 0.0 0.1 0.0 1.0 0.2 0.7 5.3 0.0 0.5 21.6 5.8 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 3076.8;skeletal muscle: 3060.2;tongue: 4911.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 1848.3" "Group enriched" "Detected in all" 5 "melanoma: 210.5;ovarian cancer: 110.1;thyroid cancer: 123.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Hep G2: 325.8;SK-MEL-30: 1130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 290000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: AB_2315307, HPA006462: AB_1079857" "unprognostic (6.13e-2)" "unprognostic (7.60e-2)" "unprognostic (5.96e-5)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.19e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-3)" "unprognostic (6.83e-3)" "unprognostic (5.22e-1)" "unprognostic (5.04e-3)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.68e-1)" "unprognostic (4.56e-2)" "unprognostic (2.70e-3)" "unprognostic (9.74e-4)" 179.7 8.3 811.3 6.5 898.6 2.3 77.2 851.4 952.4 2.9 643.9 14.5 11.1 4.2 1.0 81.0 41.8 4.9 3076.8 779.4 813.6 194.9 4.5 3.9 5.1 907.6 894.8 2.0 16.8 160.9 54.6 18.1 871.2 29.0 1.2 36.5 622.1 9.3 3060.2 23.0 6.9 1.6 847.7 4.2 23.1 5.9 882.9 9.4 167.9 4911.5 4.0 4.3 2.9 967.6 6.0 3.4 3.9 33.7 0.5 0.2 2.9 7.7 0.2 0.6 0.2 6.6 3.4 3.7 137.7 0.6 2.7 10.3 0.3 0.4 0.0 4.2 3.3 8.2 5.4 325.8 0.4 3.0 2.3 0.7 0.0 0.0 0.1 7.9 0.0 1.5 27.2 3.7 0.1 10.6 1.2 4.9 1.8 4.3 2.6 22.5 3.3 8.0 6.0 12.1 6.1 1.9 3.5 10.6 1130.2 11.1 32.8 16.2 2.7 3.3 2.8 3.0 3.8 6.1 5.7 6.2 2.5 6.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 811.3 898.6 851.4 952.4 779.4 813.6 907.6 894.8 871.2 847.7 882.9 967.6 4.3 0.0 0.0 59.4 9.5 9.7 1.2 0.4 1.8 1.1 369.9 354.1 74.4 8.6 0.2 154.5 2.1 1.1 5.9 1.1 162.4 0.9 0.6 90.5 17.3 5.3 1.8 0.0 0.3 3.7 1.9 6.0 0.0 193.3 0.0 0.0 7.9 4.7 199.1 0.0 0.3 3.7 0.0 0.6 3.5 2.2 6.5 15.6 341.5 2.8 0.0 163.5 0.0 2.0 45.8 1.9 0.6 9.1 0.0 1.8 0.9 1848.3 0.2 2.7 0.0 67.0 4.2 3.8 2.8 1.0 2.3 3.4 8.2 2.3 1.8 0.7 S100A11 S100C ENSG00000163191 "S100 calcium binding protein A11" P31949 1 152032506-152047907 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 4751.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5473.4;Extravillous trophoblasts: 6093.0;Pancreatic endocrine cells: 6926.5;Urothelial cells: 6250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 17820.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034320, HPA042745" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 7900000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB034320: AB_2183487, HPA042745: AB_2678142" "unprognostic (1.85e-2)" "unprognostic (9.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (3.12e-2)" "unprognostic (7.61e-2)" "prognostic unfavorable (3.64e-5)" "unprognostic (3.34e-2)" "unprognostic (8.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.28e-3)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.24e-6)" "unprognostic (2.91e-1)" "unprognostic (2.75e-1)" "unprognostic (2.43e-3)" "unprognostic (8.86e-2)" 656.7 214.3 92.6 487.2 92.8 415.2 574.7 99.1 222.3 1070.5 106.8 303.0 181.6 297.7 675.4 4751.5 611.1 437.8 354.1 92.3 104.4 882.5 127.6 776.0 206.7 118.1 108.6 152.0 264.1 905.1 210.7 723.2 118.0 536.4 328.7 8.4 1247.1 544.1 91.0 894.7 239.5 468.3 110.2 713.7 482.6 68.9 124.1 303.5 325.3 150.9 959.9 1527.7 1771.1 126.8 1889.0 1483.7 70.5 542.1 1960.9 2451.3 1172.4 1796.3 2626.0 1439.7 1464.8 697.6 2066.0 2.5 1571.4 2355.4 1142.4 2595.4 73.7 3254.0 814.0 913.6 149.2 162.6 830.1 409.1 1511.3 149.6 1098.4 1867.2 3255.1 1577.8 1974.9 826.9 1116.1 0.3 340.9 352.1 2137.7 3058.8 19.8 694.0 513.9 4043.1 1491.9 2.5 757.1 1426.0 4361.1 3196.5 2.5 115.8 1367.7 1797.9 1255.3 1727.2 1378.9 1612.5 1584.8 757.0 533.1 1188.8 975.7 2.5 17.0 8.2 1713.0 490.9 915.2 7956.3 4682.6 7210.4 713.6 4560.1 939.4 354.9 1346.4 845.1 3020.5 252.7 391.5 437.0 17820.3 740.5 4871.8 1042.8 1269.9 5289.9 92.6 92.8 99.1 222.3 92.3 104.4 118.1 108.6 118.0 110.2 124.1 126.8 718.5 137.8 189.4 1.3 136.6 2210.3 3924.9 5473.4 1027.8 0.7 686.8 823.8 30.8 546.2 2673.9 2284.2 0.0 3257.0 384.0 421.7 1019.3 4344.5 277.6 1738.8 561.2 617.8 277.7 52.6 0.0 4330.2 6093.0 890.7 676.4 1503.0 437.6 251.1 372.6 11.6 3806.0 0.0 0.0 479.6 1485.2 1216.7 2054.0 634.0 320.9 1971.8 1243.3 15.9 2265.2 0.8 371.8 0.0 0.0 6926.5 690.2 258.4 153.8 4365.0 343.9 925.4 2674.2 2.4 210.4 536.2 1054.9 14.5 34.8 4207.9 2822.4 3753.1 470.4 334.8 500.2 6250.2 S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 3084.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 28.3" "Group enriched" "Detected in all" 5 "dendritic cells: 11.9;NK-cells: 28.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 811.3;SuSa: 896.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 36000 "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" 275.3 137.3 237.4 47.7 247.3 4.4 222.4 241.0 347.5 133.7 214.6 198.9 30.6 111.8 72.1 91.7 129.8 103.9 310.1 233.1 240.8 262.2 66.2 138.0 48.8 252.9 245.5 138.2 75.7 317.4 73.9 70.1 249.4 100.9 59.8 25.8 156.1 64.6 250.6 114.0 116.5 68.9 245.8 111.7 94.4 41.2 251.6 21.2 318.7 220.6 49.6 121.2 122.7 258.6 188.7 153.7 174.5 111.4 150.7 437.5 62.7 254.7 400.0 150.6 172.2 150.4 203.7 4.9 471.6 435.5 22.3 174.7 73.5 158.7 132.7 0.8 68.1 12.0 178.0 129.6 99.8 5.9 39.2 355.3 59.4 135.3 145.0 441.9 346.5 1.3 61.4 0.3 475.2 663.4 0.4 3.4 141.0 161.1 460.2 30.0 180.4 1.4 811.3 141.9 53.4 2.0 544.7 277.2 576.7 896.9 226.4 6.8 495.0 103.3 57.9 139.5 312.0 2.0 5.3 9.3 185.5 3.2 62.1 4.1 2.0 0.2 0.4 0.9 0.9 4.1 0.4 0.3 7.0 2.0 0.6 0.5 0.3 28.3 1.4 11.9 1.4 1.1 237.4 247.3 241.0 347.5 233.1 240.8 252.9 245.5 249.4 245.8 251.6 258.6 331.0 28.9 106.1 29.7 9.3 110.5 177.4 105.0 103.0 2.1 311.2 345.6 141.9 164.5 104.0 465.3 0.0 132.4 15.3 148.7 248.4 323.3 8.4 399.3 449.1 251.9 124.7 17.3 1.2 323.6 202.1 450.0 58.6 573.8 23.5 185.5 372.3 51.8 162.3 0.0 0.5 167.5 61.1 31.7 107.7 36.3 771.7 37.1 238.3 13.1 14.8 308.1 1.0 0.0 8.8 488.4 164.7 314.1 6.3 240.0 128.7 521.7 77.1 6.9 0.0 234.2 132.5 12.8 23.4 80.3 75.7 74.7 20.5 3084.7 100.6 244.3 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 94.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.4;Ductal cells: 21.7;Endometrial stromal cells: 18.4;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 24.2;Skeletal myocytes: 24.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 26.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.2;plasmacytoid DC: 7.4" "Group enriched" "Detected in many" 11 "dendritic cells: 7.4;monocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 87.0;HBEC3-KT: 45.7;HeLa: 51.4;U-2197: 47.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.8" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 240000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: AB_10796581, HPA056140: AB_2683050" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.34e-3)" "unprognostic (3.97e-3)" "prognostic unfavorable (1.61e-6)" "unprognostic (8.13e-2)" "unprognostic (3.46e-1)" "unprognostic (6.21e-2)" "unprognostic (8.10e-2)" 7.6 1.1 0.9 3.6 1.1 1.8 4.2 0.8 1.3 6.9 0.6 2.8 0.5 3.9 0.2 17.2 3.3 1.7 2.6 0.8 1.4 13.8 0.2 16.6 1.8 1.4 1.6 1.1 0.8 0.1 0.7 2.2 1.2 3.0 1.1 0.0 4.2 1.7 1.0 94.6 1.9 2.1 1.1 0.8 1.4 0.5 2.8 0.4 1.5 1.9 5.1 6.9 9.6 1.4 7.3 87.0 0.1 0.1 8.1 5.2 0.0 6.1 31.4 7.9 12.8 2.6 2.8 0.1 19.0 16.1 10.7 22.2 0.1 45.7 3.7 0.3 0.0 0.3 51.4 15.3 2.2 0.0 0.3 4.1 24.9 17.9 19.9 4.5 1.7 0.0 0.0 0.0 39.8 0.5 0.0 0.0 0.6 0.2 11.5 0.0 5.9 4.7 26.0 18.3 1.2 0.0 5.4 6.1 2.0 24.7 0.2 0.6 8.6 2.9 4.8 47.4 6.3 1.4 1.6 0.2 38.2 0.7 19.1 0.0 0.1 0.0 0.0 3.1 0.2 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.2 7.4 0.1 0.4 0.9 1.1 0.8 1.3 0.8 1.4 1.4 1.6 1.2 1.1 2.8 1.4 2.0 3.2 0.5 0.7 0.0 10.3 2.3 15.4 4.0 0.0 0.3 0.4 0.3 1.5 5.9 0.0 0.0 0.3 0.0 0.0 1.9 21.7 0.0 2.3 18.4 7.4 0.0 1.3 0.0 24.0 4.4 8.4 0.0 1.3 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.1 0.1 4.1 0.4 1.8 0.0 3.6 0.0 0.0 0.0 0.0 24.2 0.0 0.4 0.0 1.5 0.0 0.3 1.1 0.0 0.0 24.7 9.6 0.1 0.0 5.6 6.5 1.5 0.5 1.1 0.0 2.0 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 1499.3;choroid plexus: 781.0" "Cell type enhanced" "Detected in many" "Astrocytes: 126.3;Breast myoepithelial cells: 124.8;Granulosa cells: 261.7;Langerhans cells: 206.8;Melanocytes: 99.6;Oligodendrocytes: 332.1" "Group enriched" "Detected in all" 58 "glioma: 463.5;melanoma: 495.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 360.9" "Lineage enriched" "Detected in all" 6 "T-cells: 360.9" "Group enriched" "Detected in some" 7 "SK-MEL-30: 547.1;WM-115: 992.8" "CAB000073, HPA015768, CAB078196" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "CAB000073: AB_10013383, CAB078196: AB_2665776, HPA015768: AB_1856538" "unprognostic (5.67e-3)" "unprognostic (6.39e-3)" "unprognostic (2.08e-3)" "unprognostic (2.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.57e-3)" "unprognostic (6.70e-2)" "unprognostic (4.41e-7)" "unprognostic (3.55e-2)" "unprognostic (7.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" 151.1 25.7 877.1 10.5 1072.5 2.3 87.0 1254.5 1191.2 28.6 781.0 121.0 7.4 2.4 12.1 14.6 6.9 14.3 28.1 858.4 989.0 3.6 3.2 6.4 21.4 1491.0 1054.2 5.6 5.0 0.3 44.7 0.8 1359.0 29.3 14.2 14.1 19.3 26.2 3.6 15.8 36.3 6.8 1162.2 26.2 23.6 2.4 998.8 18.4 5.2 6.4 20.3 15.9 26.9 1499.3 0.5 0.0 110.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.9 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 15.9 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 2.5 0.0 0.0 547.1 0.0 0.1 0.5 0.0 0.3 0.3 0.0 3.2 0.0 0.3 0.0 1.4 6.7 992.8 0.1 0.5 0.2 360.9 9.5 103.3 0.2 1.0 67.6 16.3 1.4 3.2 153.1 3.2 58.7 10.1 3.9 0.0 63.6 877.1 1072.5 1254.5 1191.2 858.4 989.0 1491.0 1054.2 1359.0 1162.2 998.8 1499.3 4.5 3.2 4.8 126.3 4.6 16.8 0.7 0.0 17.6 1.3 41.2 124.8 6.0 0.0 0.0 0.0 0.0 0.0 14.7 0.1 0.0 0.1 0.4 0.1 0.1 2.7 0.0 2.7 0.9 0.0 0.1 4.4 0.5 0.2 0.0 261.7 4.6 0.4 9.3 0.0 1.4 0.0 0.0 38.6 206.8 1.7 5.6 37.0 99.6 9.4 33.3 25.7 63.8 83.4 332.1 0.1 0.0 0.0 2.2 0.1 0.0 0.1 0.0 4.7 0.0 5.6 7.8 0.1 0.1 0.7 12.6 0.1 37.9 0.0 0.2 0.4 S100Z "Gm625, S100-zeta" ENSG00000171643 "S100 calcium binding protein Z" Q8WXG8 5 76850001-76921650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 7.4;Kupffer cells: 8.7;Macrophages: 11.8;Microglial cells: 32.8;monocytes: 26.1" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 35.0;eosinophil: 31.8;intermediate monocyte: 34.0;myeloid DC: 19.5;neutrophil: 11.8;non-classical monocyte: 39.6" "Group enriched" "Detected in many" 6 "dendritic cells: 19.5;granulocytes: 31.8;monocytes: 39.6" "Cell line enriched" "Detected in some" 6 "U-698: 81.9" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" HPA051929 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Centrosome, Cytosol" Nucleoplasm "HPA051929: AB_2732571" "unprognostic (4.17e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-4)" "unprognostic (1.86e-1)" "unprognostic (4.62e-2)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (8.89e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-3)" "unprognostic (1.32e-1)" "unprognostic (9.47e-5)" "unprognostic (3.39e-4)" "unprognostic (8.94e-2)" "unprognostic (6.85e-2)" "unprognostic (1.62e-1)" 0.3 0.2 1.1 2.0 0.6 2.4 0.2 0.4 1.1 0.0 0.1 0.3 0.4 0.1 0.1 0.3 0.1 0.7 0.1 0.5 0.5 0.1 0.3 0.7 0.9 0.6 0.6 0.0 0.9 0.1 0.1 1.2 0.6 0.2 0.4 0.0 0.2 0.1 0.2 0.0 0.8 0.6 0.5 3.2 0.4 0.2 1.0 0.8 0.1 0.0 2.5 0.5 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 2.7 0.1 0.2 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.1 1.0 0.1 81.9 3.3 0.0 0.0 2.5 35.0 31.8 0.8 34.0 0.2 4.7 0.5 0.1 19.5 2.1 0.0 0.0 11.8 0.7 39.6 0.1 0.7 10.5 1.1 0.6 0.4 1.1 0.5 0.5 0.6 0.6 0.6 0.5 1.0 1.1 0.2 0.0 0.0 0.3 2.7 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 2.1 2.1 0.0 0.2 0.2 0.5 0.2 0.0 0.5 0.4 0.0 7.4 0.0 2.0 0.0 0.0 8.7 1.1 0.0 0.0 11.8 3.6 32.8 26.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.1 1.4 0.0 0.0 0.0 SAFB2 KIAA0138 ENSG00000130254 "Scaffold attachment factor B2" Q14151 19 5586999-5624046 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050894 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 48000 "Cluster 38: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Vesicles" "HPA050894: AB_2681266" "unprognostic (7.46e-2)" "unprognostic (3.09e-1)" "unprognostic (7.69e-3)" "prognostic favorable (7.10e-4)" "unprognostic (7.95e-2)" "unprognostic (6.76e-3)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.11e-1)" "unprognostic (5.14e-2)" "prognostic favorable (2.53e-4)" "unprognostic (2.23e-2)" "unprognostic (2.82e-3)" "unprognostic (1.17e-2)" "unprognostic (1.55e-1)" "unprognostic (4.11e-2)" "prognostic favorable (2.12e-4)" 26.8 35.8 23.3 22.4 23.8 35.2 25.8 28.0 30.3 48.4 21.0 35.3 22.2 38.2 21.0 23.1 44.0 15.6 30.8 21.7 29.6 40.6 30.7 27.8 24.4 24.2 23.9 56.2 30.5 18.0 48.6 14.2 23.1 43.0 16.1 34.7 27.6 18.6 41.5 25.8 34.3 19.3 17.5 39.9 27.8 32.5 23.9 22.3 38.9 20.4 21.2 31.5 35.0 27.5 44.9 54.8 38.8 30.4 36.7 23.7 47.6 40.9 21.3 24.4 23.3 69.9 31.4 84.9 36.9 19.9 19.6 39.9 47.2 24.9 39.2 59.8 53.5 64.4 59.5 54.6 21.2 53.0 58.2 23.5 25.4 35.2 26.9 23.9 24.6 29.3 63.6 40.6 28.7 48.9 65.7 53.1 69.9 33.1 59.9 82.2 34.2 47.6 27.7 70.5 37.6 35.3 54.7 25.3 35.3 24.4 36.5 33.0 40.5 30.7 32.7 39.3 57.6 55.2 52.2 58.6 31.2 47.1 52.2 42.8 12.6 22.0 14.6 10.8 16.8 13.9 13.2 11.7 11.3 14.9 14.5 11.7 23.4 9.4 12.3 12.5 13.4 7.9 23.3 23.8 28.0 30.3 21.7 29.6 24.2 23.9 23.1 17.5 23.9 27.5 40.6 41.7 45.1 79.7 69.7 46.7 58.1 41.4 47.3 70.2 39.1 30.6 28.7 20.0 39.3 33.1 75.0 46.8 63.0 46.4 23.5 49.7 7.6 44.5 92.6 49.0 43.0 45.8 36.2 44.4 44.7 47.3 44.4 58.3 42.3 45.4 26.7 23.3 30.6 43.7 42.7 46.5 57.0 27.6 49.5 13.3 72.4 46.6 26.6 32.8 52.2 77.5 52.5 29.7 34.6 42.2 48.6 65.8 70.0 50.3 54.1 61.5 55.3 78.4 46.0 75.4 47.9 68.3 78.8 37.3 41.9 32.3 79.1 59.7 44.8 54.2 SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135975-51151367 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;kidney: 36.4;liver: 36.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Cone photoreceptor cells: 25.0;Endometrial stromal cells: 17.5;Glandular and luminal cells: 14.3;Hepatocytes: 30.1;Microglial cells: 26.2;Oligodendrocytes: 47.6;Proximal tubular cells: 20.3" "Cancer enhanced" "Detected in many" "glioma: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 29.5;BJ hTERT+: 25.3;NTERA-2: 48.0;RPTEC TERT1: 40.4;U-87 MG: 46.2" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: AB_2680902, HPA074673: " "unprognostic (9.91e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-6)" "prognostic favorable (1.28e-4)" "unprognostic (2.55e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-2)" "unprognostic (4.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.96e-1)" "prognostic favorable (1.91e-7)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (3.03e-2)" "unprognostic (1.76e-1)" 0.3 0.0 18.0 0.6 29.2 0.1 0.3 29.7 21.3 19.6 2.1 2.6 1.0 17.4 0.0 0.3 11.0 0.4 0.8 17.9 21.7 36.4 36.5 0.0 0.0 41.0 32.2 4.5 1.0 6.5 6.5 3.9 36.6 0.8 2.6 4.6 0.2 1.6 0.0 0.2 1.3 8.4 31.1 0.0 2.5 1.7 26.6 0.1 23.7 0.2 0.0 2.8 7.2 40.2 0.0 1.7 29.5 0.2 0.8 0.6 0.0 10.0 25.3 0.6 1.4 0.0 0.0 0.0 11.2 14.1 8.8 0.0 18.6 0.0 0.9 0.0 11.3 0.0 0.0 18.5 0.7 0.0 8.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 48.0 0.0 0.0 3.8 1.9 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 46.2 0.0 10.0 0.2 0.6 0.5 0.1 0.4 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.3 0.4 0.2 0.3 18.0 29.2 29.7 21.3 17.9 21.7 41.0 32.2 36.6 31.1 26.6 40.2 0.0 0.0 0.0 15.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 1.4 10.0 0.0 9.2 25.0 0.0 0.0 0.0 11.7 0.5 0.7 8.9 17.5 0.9 0.0 2.7 0.2 0.0 0.0 1.6 0.0 14.3 0.0 0.0 0.7 30.1 0.1 0.0 8.2 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 26.2 0.0 0.5 0.0 5.0 47.6 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 1.0 0.0 0.0 0.5 0.2 2.3 0.0 0.1 0.0 0.3 0.6 0.0 0.1 SAMD15 "C14orf174, FAM15A, FLJ35963" ENSG00000100583 "Sterile alpha motif domain containing 15" Q9P1V8 14 77376689-77391497 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 15.3;testis: 17.7" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 62.6;Early spermatids: 81.8;Endometrial ciliated cells: 38.8;Late spermatids: 111.7;Respiratory ciliated cells: 41.5;Rod photoreceptor cells: 75.7;Spermatocytes: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 7.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030673, HPA030677" Enhanced Approved "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear membrane, Nucleoli" "HPA030673: AB_10600655, HPA030677: AB_10599938" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (3.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-2)" "unprognostic (1.38e-2)" "unprognostic (3.70e-3)" "unprognostic (5.20e-2)" "unprognostic (5.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.83e-3)" "unprognostic (6.19e-2)" "unprognostic (2.53e-3)" "unprognostic (6.87e-3)" "unprognostic (9.90e-2)" "unprognostic (3.73e-3)" "unprognostic (1.76e-2)" 0.5 0.8 1.7 0.3 2.8 0.6 1.0 0.7 1.5 0.7 7.7 0.2 0.3 1.0 5.3 0.2 4.5 1.1 0.1 1.7 3.4 1.9 0.1 0.8 1.4 2.8 3.5 0.7 2.0 2.4 2.4 0.3 2.0 0.7 0.3 15.3 0.3 0.7 0.2 0.5 0.2 0.3 1.4 0.2 0.4 17.7 2.7 0.4 3.9 0.0 1.4 0.8 0.2 0.8 2.5 3.4 1.3 2.7 0.3 1.4 1.2 1.0 0.9 2.6 2.3 2.5 2.2 2.8 1.1 1.0 2.3 2.4 0.9 1.4 3.7 0.2 0.5 0.4 1.0 0.6 0.1 0.5 2.9 1.3 0.9 2.3 0.2 1.1 1.8 1.4 0.3 0.7 1.1 7.6 0.6 0.2 0.5 0.6 1.0 1.2 1.2 0.1 4.6 1.4 2.8 1.8 3.5 0.5 0.5 0.5 4.3 0.8 0.7 2.5 1.4 2.6 1.3 0.4 2.4 1.8 3.1 0.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.7 2.8 0.7 1.5 1.7 3.4 2.8 3.5 2.0 1.4 2.7 0.8 0.7 0.0 0.0 1.0 0.3 0.3 0.5 0.6 0.0 11.2 0.9 0.9 1.9 2.8 1.8 0.0 62.6 0.3 0.8 0.7 1.9 2.8 81.8 38.8 4.6 0.5 3.6 0.0 1.3 0.6 0.2 1.0 0.0 1.4 0.0 1.3 0.4 0.0 0.1 3.3 0.6 0.5 0.0 0.0 0.0 111.7 1.5 0.3 0.0 0.0 0.1 5.5 0.0 0.5 0.4 0.9 0.1 0.0 0.0 0.2 0.0 3.5 41.5 75.7 0.0 1.0 1.0 59.3 7.3 0.0 0.0 0.3 0.3 6.0 0.1 0.3 SAP18 "2HOR0202, MGC27131, SAP18p" ENSG00000150459 "Sin3A associated protein 18" O00422 13 21140514-21149084 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011352, CAB012273" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" Cytosol "CAB012273: , HPA011352: AB_1856563" "unprognostic (5.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-3)" "unprognostic (2.84e-1)" "unprognostic (5.21e-2)" "unprognostic (3.02e-1)" "unprognostic (3.18e-1)" "unprognostic (8.15e-2)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (4.14e-2)" "unprognostic (2.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.70e-2)" "unprognostic (3.70e-3)" "unprognostic (2.78e-2)" 125.7 164.3 140.9 122.9 152.2 242.3 121.6 149.6 198.9 120.4 137.8 141.8 137.4 123.8 97.5 159.2 112.9 82.4 195.8 147.4 160.7 190.4 171.1 106.5 118.0 154.7 153.8 109.5 134.6 114.2 129.6 111.7 157.7 109.7 58.5 89.5 126.3 73.0 297.9 119.5 127.5 51.7 164.1 107.6 119.5 194.3 155.7 115.5 110.7 156.3 64.8 131.7 118.5 170.7 182.1 99.3 159.5 173.1 169.0 140.5 246.9 227.1 167.2 205.5 151.3 181.1 342.4 187.3 272.0 189.1 223.4 186.5 198.1 142.4 231.5 288.0 100.4 267.6 121.2 305.9 191.8 367.1 207.5 143.0 159.7 157.5 187.1 158.4 157.3 223.1 128.8 103.6 188.2 231.0 417.0 599.0 200.7 501.5 109.7 261.1 251.4 187.1 295.7 160.7 185.0 161.1 145.7 213.8 296.5 176.5 206.8 528.0 192.6 126.0 141.9 230.1 268.9 159.6 243.6 536.7 122.5 214.9 236.4 433.0 431.5 540.0 344.1 485.0 349.3 493.7 418.2 410.9 427.8 443.6 405.9 402.9 430.5 395.3 547.4 568.8 517.5 909.3 140.9 152.2 149.6 198.9 147.4 160.7 154.7 153.8 157.7 164.1 155.7 170.7 638.0 134.6 143.5 15.0 291.7 458.6 336.3 640.9 310.7 101.5 298.9 594.9 592.9 194.5 383.8 233.6 41.7 566.2 397.4 353.6 759.2 396.5 1259.5 334.1 231.1 273.1 234.5 214.4 20.8 365.6 528.0 374.0 170.2 256.2 258.6 176.6 180.2 242.0 396.0 119.5 23.4 364.5 468.0 189.5 440.9 206.0 342.3 260.4 407.4 17.8 385.0 370.8 233.8 19.6 26.2 401.9 417.6 303.6 182.3 325.9 475.0 1100.6 446.8 132.3 203.8 362.5 438.3 547.7 319.9 271.7 422.2 908.3 338.8 254.2 344.7 419.9 SAPCD2 "C9orf140, p42.3" ENSG00000186193 "Suppressor APC domain containing 2" Q86UD0 9 137062127-137070557 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1;esophagus: 8.5;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 10.8;Oligodendrocyte precursor cells: 29.7;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 122.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044154 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA044154: AB_10959464" "unprognostic (3.68e-2)" "unprognostic (9.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-1)" "unprognostic (5.42e-8)" "prognostic unfavorable (5.88e-4)" "unprognostic (8.33e-2)" "unprognostic (7.47e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-7)" "unprognostic (4.37e-3)" "unprognostic (4.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" 0.5 0.3 6.9 2.4 5.1 2.0 1.3 4.7 5.4 1.2 1.3 3.7 4.3 0.4 0.0 8.5 0.3 0.2 0.2 5.4 4.5 1.2 0.2 0.5 2.7 7.1 6.8 0.1 0.4 0.0 0.5 0.9 5.7 3.1 1.8 0.1 4.1 0.1 0.1 6.2 4.3 0.4 5.0 2.2 2.4 0.5 6.8 2.3 0.3 0.0 2.5 0.4 2.3 7.0 52.1 27.5 10.7 32.0 0.3 0.7 57.1 8.4 5.7 8.8 4.1 52.5 23.2 53.8 26.5 4.1 8.2 72.3 33.6 9.7 2.0 37.4 38.9 23.6 32.7 59.6 0.2 27.0 39.2 0.1 1.5 3.0 5.8 2.3 14.4 27.1 33.1 23.7 2.6 122.1 7.8 72.7 19.9 119.2 61.9 82.9 40.7 60.1 10.9 14.8 55.2 32.7 32.2 89.1 12.2 2.4 71.9 51.1 9.4 7.9 26.6 24.0 41.9 8.2 25.5 26.3 18.4 31.8 25.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.9 5.1 4.7 5.4 5.4 4.5 7.1 6.8 5.7 5.0 6.8 7.0 0.5 0.0 0.0 0.7 1.9 4.2 0.7 0.5 0.6 0.2 5.0 5.2 1.3 0.0 1.1 0.0 0.0 2.8 1.6 5.4 1.9 0.3 0.0 1.6 0.8 0.9 0.0 3.6 0.2 0.0 3.5 1.1 6.1 6.0 0.0 3.3 1.4 0.0 3.1 0.0 0.2 10.8 0.0 2.8 1.5 0.1 0.0 2.2 0.0 0.0 1.5 0.5 0.0 29.7 5.6 0.6 4.0 0.0 1.8 2.1 0.5 0.0 0.1 0.6 0.0 0.2 1.0 0.0 1.4 5.8 2.7 0.5 1.3 0.6 12.1 1.1 SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Late spermatids: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" 7.3 17.3 4.2 7.2 4.7 9.3 8.2 4.4 6.8 9.7 3.6 10.1 9.3 9.3 2.8 14.3 8.5 5.9 12.4 4.7 4.4 14.6 18.7 6.6 9.8 5.0 4.4 9.8 15.9 7.8 11.9 7.6 5.3 12.2 5.3 2.3 11.3 6.2 16.4 12.3 10.2 5.1 4.2 12.0 11.9 10.7 4.4 7.5 14.4 11.5 6.6 9.4 9.6 5.4 17.6 47.3 15.5 10.7 5.8 13.3 23.7 10.7 12.6 23.1 17.7 36.0 18.4 17.2 16.3 12.5 9.7 13.9 14.7 29.2 5.3 12.7 24.4 33.7 17.7 32.0 15.4 29.1 31.9 20.7 13.5 14.5 7.6 9.5 14.2 26.3 29.9 14.2 10.6 28.4 21.4 20.7 18.5 21.6 8.5 31.2 16.4 18.6 20.5 36.2 29.1 18.1 14.2 32.7 8.9 4.6 21.8 19.1 11.4 13.7 17.7 11.7 15.1 11.0 7.1 13.2 10.9 18.5 13.8 0.0 8.0 1.0 14.2 14.4 11.5 12.0 10.7 14.7 25.2 10.7 7.5 8.6 0.5 14.0 13.7 9.9 13.4 8.9 4.2 4.7 4.4 6.8 4.7 4.4 5.0 4.4 5.3 4.2 4.4 5.4 2.7 6.4 7.9 6.2 8.4 4.2 3.8 8.3 3.4 8.0 7.0 5.3 8.1 7.2 6.8 5.5 8.4 40.1 5.6 8.9 15.6 15.5 15.7 3.6 3.6 3.8 11.4 13.2 6.8 12.7 23.0 4.8 9.7 3.9 5.7 7.4 6.1 10.1 12.9 5.0 6.7 9.2 10.2 6.7 4.2 56.9 4.7 4.8 3.6 1.9 7.7 3.1 5.2 1.5 3.1 8.4 5.6 4.9 10.1 2.6 7.4 10.3 5.1 13.4 0.0 2.7 4.2 1.9 8.2 12.8 4.1 29.1 7.4 10.6 17.8 3.2 SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 108.1;intestine: 36.5;lymphoid tissue: 120.7" "Cell type enhanced" "Detected in some" "B-cells: 69.5;dendritic cells: 66.3;Hofbauer cells: 51.3;Kupffer cells: 58.9;Macrophages: 40.0;monocytes: 45.3;NK-cells: 101.0;Plasma cells: 39.8;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 164.1;JURKAT: 119.4;MOLT-4: 120.6;NB-4: 89.1;REH: 88.5;U-698: 150.2;U-937: 117.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 14000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: AB_2184289" "unprognostic (1.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.49e-3)" "prognostic favorable (3.15e-4)" "unprognostic (1.12e-1)" "unprognostic (1.19e-3)" "unprognostic (1.67e-1)" "unprognostic (3.23e-3)" "unprognostic (7.92e-3)" "unprognostic (3.45e-1)" "unprognostic (8.75e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (3.30e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" 8.6 5.6 5.2 61.8 5.6 108.1 4.3 5.4 7.4 3.2 5.1 9.4 11.6 3.1 1.8 3.6 4.9 10.2 2.7 4.8 6.4 3.7 5.9 21.3 120.6 9.6 7.0 1.8 2.5 1.5 2.2 7.5 8.4 4.2 9.9 0.2 7.9 2.2 1.3 2.1 36.5 7.5 7.5 100.3 13.6 1.3 8.4 120.7 3.9 1.7 108.2 15.4 3.0 10.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.7 0.0 0.0 0.0 58.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 119.4 0.2 13.6 0.0 0.0 120.6 89.1 0.0 0.0 0.0 88.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 24.0 0.3 0.0 0.3 0.1 0.1 0.1 35.0 150.2 0.0 117.2 0.0 41.6 135.4 245.5 192.2 195.3 159.1 79.1 108.2 178.9 121.5 90.8 76.9 120.9 128.0 153.3 209.9 55.1 145.6 343.7 5.2 5.6 5.4 7.4 4.8 6.4 9.6 7.0 8.4 7.5 8.4 10.2 0.8 0.0 3.6 0.0 69.5 0.5 0.1 0.0 0.0 0.0 0.5 1.1 1.0 1.5 0.0 0.0 0.0 0.5 66.3 0.1 0.0 0.1 0.1 0.2 0.2 1.2 0.0 13.5 0.2 0.0 0.6 0.9 2.6 0.3 22.2 0.0 3.3 0.9 51.3 0.0 0.2 0.1 0.0 58.9 19.1 0.0 0.3 40.0 0.0 7.5 45.3 0.0 101.0 0.0 0.1 0.0 0.0 0.0 39.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.1 1.3 0.5 60.6 0.0 0.1 0.0 SBF2 "CMT4B2, DENND7B, KIAA1766, MTMR13" ENSG00000133812 "SET binding factor 2" Q86WG5 11 9778667-10294219 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 224.6;Excitatory neurons: 244.9;Inhibitory neurons: 367.4;Microglial cells: 273.6;Oligodendrocyte precursor cells: 290.5;Oligodendrocytes: 228.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 105.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050933 Uncertain Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Intermediate filaments, Cytosol" "HPA050933: AB_2681280" "unprognostic (2.26e-1)" "unprognostic (1.45e-2)" "unprognostic (1.91e-2)" "unprognostic (1.00e-1)" "unprognostic (2.28e-1)" "unprognostic (5.36e-2)" "unprognostic (5.55e-2)" "unprognostic (6.44e-3)" "unprognostic (2.84e-2)" "unprognostic (1.87e-1)" "unprognostic (3.62e-3)" "unprognostic (2.43e-1)" "prognostic favorable (3.66e-5)" "unprognostic (3.72e-2)" "unprognostic (8.77e-2)" "unprognostic (3.43e-1)" "unprognostic (4.11e-2)" 13.3 7.6 8.6 6.2 9.2 4.0 9.2 6.4 7.7 15.2 5.1 9.3 6.8 11.3 9.1 11.6 10.2 10.4 8.9 6.7 7.7 13.8 9.5 7.4 3.9 6.9 8.1 18.0 5.1 17.1 4.6 14.2 7.2 10.6 10.5 14.9 9.3 11.4 4.7 7.4 6.6 10.9 7.1 7.8 9.5 10.8 7.1 6.1 16.7 8.9 4.2 11.2 8.2 8.2 15.1 12.1 20.8 15.0 27.1 35.4 105.4 11.6 20.9 13.1 18.2 9.1 18.1 5.8 6.2 20.6 19.1 9.8 12.5 9.8 22.9 6.2 8.6 2.5 9.1 11.9 10.6 5.6 8.0 17.5 12.3 6.6 25.8 20.2 21.8 12.1 5.1 5.2 15.8 4.3 8.1 1.5 9.1 13.5 13.3 7.5 14.5 7.6 11.9 13.4 6.9 15.4 15.7 22.4 10.0 10.6 6.7 4.0 24.4 23.1 11.5 24.3 9.5 1.7 4.6 8.0 17.4 2.7 17.0 0.0 0.7 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.2 0.1 0.0 1.1 0.3 1.6 0.1 0.1 0.2 8.6 9.2 6.4 7.7 6.7 7.7 6.9 8.1 7.2 7.1 7.1 8.2 50.2 44.8 83.9 224.6 16.4 25.5 43.4 24.1 27.3 35.1 16.4 14.5 31.4 22.8 30.8 16.5 75.0 13.8 14.6 20.3 3.9 13.9 18.3 17.8 31.1 40.9 43.8 11.4 244.9 8.8 12.9 40.0 40.8 30.1 21.5 41.7 49.6 16.6 18.6 37.0 367.4 16.2 24.4 55.0 34.1 9.2 51.0 44.8 30.2 273.6 37.6 12.0 29.9 290.5 228.4 13.5 21.2 27.1 9.5 56.5 14.5 13.1 38.3 71.6 26.3 44.0 34.8 24.5 17.4 30.6 30.7 13.8 20.6 25.9 20.1 47.4 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCAMP1 SCAMP37 ENSG00000085365 "Secretory carrier membrane protein 1" O15126 5 78360611-78480739 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044753, CAB079009" Supported Uncertain "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB079009: , HPA044753: " "unprognostic (8.25e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-3)" "unprognostic (5.34e-3)" "unprognostic (2.60e-1)" "unprognostic (2.57e-3)" "unprognostic (5.51e-2)" "unprognostic (3.43e-2)" "unprognostic (1.31e-1)" "unprognostic (8.23e-3)" "unprognostic (2.35e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.92e-4)" "unprognostic (8.44e-3)" "unprognostic (7.56e-2)" "unprognostic (3.12e-2)" "unprognostic (4.99e-2)" 17.9 22.4 18.4 12.7 20.5 8.5 28.2 24.5 29.1 23.9 23.9 19.6 16.0 25.0 23.2 24.7 29.6 20.2 24.7 20.4 22.4 28.6 17.8 17.8 12.1 18.4 21.5 22.8 25.2 47.1 15.7 23.4 21.4 34.3 22.3 40.2 31.5 29.8 10.6 17.7 15.6 26.6 20.0 13.6 27.9 14.1 23.3 14.6 39.8 16.3 13.4 25.0 11.4 19.0 32.7 23.9 23.4 76.1 35.5 45.5 40.8 30.0 46.1 26.5 56.1 9.3 61.1 48.1 31.4 45.5 65.7 26.2 34.9 57.0 45.9 17.4 32.5 20.5 17.8 20.1 22.7 13.6 16.5 28.6 54.5 27.3 41.2 62.5 41.3 25.0 8.4 33.6 50.9 39.2 25.2 26.7 19.9 14.3 26.0 29.5 38.3 55.3 43.5 38.6 70.9 40.6 27.6 38.5 26.7 24.9 52.5 26.1 36.6 26.3 19.3 30.0 24.2 20.9 29.4 27.6 50.1 50.4 22.6 20.3 11.4 13.2 7.5 12.7 9.3 7.6 8.7 9.2 14.8 6.5 7.1 6.3 6.8 10.3 16.6 4.5 9.1 8.0 18.4 20.5 24.5 29.1 20.4 22.4 18.4 21.5 21.4 20.0 23.3 19.0 59.5 25.6 22.4 45.7 20.3 39.1 31.5 33.6 38.7 72.1 33.4 22.7 36.1 21.5 30.4 40.5 70.9 13.8 21.7 19.1 13.7 24.2 42.2 34.9 30.2 31.4 35.4 12.0 80.0 30.5 24.8 34.3 36.7 34.1 12.0 41.7 27.1 15.7 19.2 32.0 100.1 34.2 20.3 33.7 33.1 15.3 20.2 25.1 30.2 45.0 19.1 47.4 19.6 76.4 60.3 29.8 14.9 28.6 23.9 44.6 14.2 24.7 65.4 68.2 13.1 33.5 25.4 25.6 23.1 30.8 45.3 10.5 21.2 30.8 18.8 33.7 SCAMP4 FLJ33847 ENSG00000227500 "Secretory carrier membrane protein 4" Q969E2 19 1905372-1926013 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043284 Approved Approved "Golgi apparatus,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" "Lipid droplets, Plasma membrane" "HPA043284: AB_10806501" "unprognostic (1.60e-1)" "unprognostic (3.62e-1)" "unprognostic (5.04e-2)" "prognostic favorable (4.40e-6)" "unprognostic (2.58e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.92e-5)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.55e-1)" "unprognostic (3.01e-3)" "unprognostic (5.66e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.16e-2)" "unprognostic (1.58e-1)" "unprognostic (3.93e-2)" "unprognostic (1.03e-1)" 23.2 27.4 31.1 15.5 39.9 11.4 25.4 41.3 33.3 28.1 33.6 23.3 19.8 26.0 17.5 39.9 38.3 19.5 15.5 28.9 33.1 34.4 28.3 25.5 15.6 51.5 42.9 27.1 36.5 15.8 31.8 18.8 47.7 31.7 9.8 7.4 43.9 20.4 13.9 36.3 20.3 12.3 39.7 25.1 26.4 22.0 40.6 8.3 32.7 5.8 9.4 22.0 25.0 53.5 53.6 53.9 25.7 56.8 50.7 31.7 29.6 35.5 33.1 39.3 46.7 44.9 51.1 22.5 32.1 30.7 23.1 63.7 24.7 38.2 14.5 34.8 21.7 15.8 19.0 44.3 65.6 16.9 23.2 48.8 24.2 34.8 21.2 32.9 27.2 25.2 35.7 25.3 23.3 67.8 21.5 31.6 38.8 31.1 18.6 25.9 18.1 34.6 49.8 47.5 33.8 45.0 23.9 49.9 31.4 18.1 50.6 41.5 29.6 44.8 30.5 81.1 35.7 57.8 62.6 21.0 59.1 26.9 30.1 1.7 4.4 1.9 3.9 4.9 2.0 5.1 2.7 2.6 4.8 3.4 1.5 2.9 2.1 5.8 4.5 12.0 2.3 3.7 31.1 39.9 41.3 33.3 28.9 33.1 51.5 42.9 47.7 39.7 40.6 53.5 16.9 9.6 7.3 12.1 22.9 17.1 25.0 20.8 33.0 19.7 40.0 23.5 3.0 21.5 14.1 49.7 75.0 40.0 59.6 53.0 7.9 20.8 0.8 63.2 23.2 17.8 18.7 11.6 8.3 12.5 38.1 18.2 43.3 42.1 17.2 27.8 15.7 13.4 38.0 21.9 8.0 36.1 20.3 20.1 24.9 1.9 21.8 24.2 21.4 5.6 21.0 29.6 33.0 16.6 18.9 16.1 25.3 17.3 16.0 30.0 47.6 10.1 33.2 52.2 0.0 15.8 15.7 19.0 26.1 30.8 20.2 59.0 20.4 26.9 31.1 28.1 SCAPER "Zfp291, ZNF291" ENSG00000140386 "S-phase cyclin A associated protein in the ER" Q9BY12 15 76347904-76905444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 55.4" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 252.3;Oligodendrocytes: 251.5;Rod photoreceptor cells: 710.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046253, HPA048077" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA No "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear speckles" Cytosol "HPA046253: AB_2679600, HPA048077: " "unprognostic (3.67e-1)" "unprognostic (8.60e-2)" "unprognostic (6.08e-2)" "unprognostic (8.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (4.94e-2)" "unprognostic (3.74e-2)" "unprognostic (5.40e-2)" "unprognostic (1.02e-1)" "prognostic favorable (2.69e-9)" "unprognostic (2.14e-1)" "unprognostic (3.79e-1)" "unprognostic (1.86e-1)" "unprognostic (2.89e-3)" 5.5 7.9 9.7 4.0 12.2 7.4 6.9 18.2 10.4 6.2 6.5 6.0 6.5 7.4 7.7 8.9 6.4 5.3 13.8 9.0 12.8 9.0 7.5 6.3 4.7 11.5 10.5 12.1 8.3 14.5 8.2 6.5 11.3 7.0 4.4 55.4 7.9 6.2 13.6 6.9 6.3 6.3 9.2 5.9 6.1 21.0 10.7 8.6 12.2 12.0 6.0 5.0 6.5 16.3 6.3 5.8 7.8 4.5 3.9 7.0 6.5 8.3 5.9 3.8 5.4 6.1 5.0 6.3 7.2 2.8 10.0 6.7 18.5 3.5 5.7 14.7 9.1 3.3 6.8 3.0 4.9 9.0 7.6 5.9 6.0 4.5 7.3 8.2 5.2 12.6 4.8 17.5 6.6 2.6 8.8 2.7 2.3 5.5 3.3 7.9 12.4 2.2 3.5 6.3 18.4 8.9 11.2 3.9 9.0 9.4 5.8 7.3 6.3 8.7 8.1 4.1 7.4 10.5 23.7 8.9 5.1 11.1 5.9 40.8 6.3 17.4 11.4 3.5 13.1 16.3 11.5 10.3 3.6 17.0 18.8 12.1 10.7 17.1 4.2 9.3 9.7 4.2 9.7 12.2 18.2 10.4 9.0 12.8 11.5 10.5 11.3 9.2 10.7 16.3 28.5 99.3 61.5 190.7 33.2 20.6 28.9 10.6 18.8 91.5 13.9 15.5 191.3 12.8 27.4 12.9 252.3 33.8 26.6 17.1 1.9 14.6 59.1 10.6 13.8 23.5 16.2 1.7 151.5 6.0 11.8 22.1 17.3 18.4 22.1 41.9 21.8 9.3 14.3 77.4 201.8 9.0 6.1 13.6 11.3 24.9 20.5 14.4 10.6 135.9 12.8 51.3 34.0 203.1 251.5 6.5 11.4 19.2 28.6 15.9 72.6 7.8 12.3 710.6 19.7 39.1 23.5 143.9 68.9 15.1 18.8 52.0 30.5 26.7 13.4 19.7 SCARB1 "CD36L1, CLA-1, CLA1, SR-BI, SRB1" ENSG00000073060 "Scavenger receptor class B member 1" Q8WTV0 12 124776856-124882668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adrenal gland: 995.8" "Cell type enhanced" "Detected in many" "Adipocytes: 133.9;Granulosa cells: 114.6;Hepatocytes: 159.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 6.2;myeloid DC: 8.9;plasmacytoid DC: 21.0" "Group enriched" "Detected in many" 6 "dendritic cells: 21.0;monocytes: 6.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 148.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066285, CAB070124, HPA072449" Enhanced Approved "Vesicles,Lysosomes,Rods & Rings" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Lysosomes, Rods & Rings" "CAB070124: AB_10107658, HPA066285: AB_2685649, HPA072449: AB_2732201" "unprognostic (9.70e-3)" "unprognostic (4.94e-3)" "unprognostic (1.32e-1)" "unprognostic (4.79e-2)" "unprognostic (1.65e-3)" "unprognostic (4.21e-3)" "prognostic unfavorable (1.83e-5)" "prognostic unfavorable (4.02e-4)" "unprognostic (2.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-2)" "prognostic unfavorable (1.49e-5)" "unprognostic (3.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-1)" 59.2 995.8 12.3 4.0 22.7 1.3 55.4 7.2 13.2 12.9 21.7 14.7 12.5 13.7 0.9 9.2 13.1 12.9 10.5 12.3 8.9 6.8 235.7 15.3 6.2 11.0 10.0 54.8 9.6 4.0 15.2 111.5 12.0 13.0 9.2 12.0 21.2 2.3 9.8 26.4 14.9 7.8 7.2 12.7 8.8 19.1 15.5 2.9 11.7 5.0 10.4 12.3 12.7 11.5 30.1 50.0 22.2 51.4 12.3 23.1 0.0 24.2 20.0 21.4 12.1 56.7 61.7 91.6 66.4 12.4 31.1 39.2 58.0 109.3 13.2 45.5 51.4 18.5 53.1 68.3 33.2 35.9 17.2 39.5 19.7 41.0 32.5 36.7 57.2 9.1 41.5 21.5 4.3 27.7 12.9 23.5 22.8 30.7 66.0 51.0 18.8 148.7 0.8 32.9 38.8 12.1 126.5 95.9 70.2 13.3 55.8 29.9 4.6 2.6 23.8 14.3 29.8 10.1 3.8 15.7 11.3 29.0 23.9 0.0 6.2 0.0 0.2 3.0 0.1 2.3 0.0 0.2 8.9 0.9 0.0 0.0 0.8 0.0 0.6 21.0 0.0 3.8 12.3 22.7 7.2 13.2 12.3 8.9 11.0 10.0 12.0 7.2 15.5 11.5 133.9 3.2 2.7 25.8 8.6 5.6 3.6 9.0 6.8 6.1 14.8 17.0 6.5 8.6 5.3 3.7 29.2 10.7 10.5 46.7 3.9 5.4 18.1 1.0 5.3 44.2 10.7 8.2 21.0 7.4 13.8 7.9 11.7 3.4 1.3 114.6 21.4 159.4 51.6 16.8 24.8 13.1 8.2 14.8 11.4 12.6 9.0 16.7 48.0 74.9 5.9 52.9 0.0 23.1 27.3 5.8 12.9 5.3 8.0 9.9 10.0 2.9 4.7 7.5 0.0 3.1 5.0 25.0 1.6 6.5 3.1 43.4 1.8 60.0 9.4 4.4 SCARF2 "HUMZD58C02, SREC-II, SREC2" ENSG00000244486 "Scavenger receptor class F member 2" Q96GP6 22 20424584-20437826 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 44.8;Fibroblasts: 21.2;Leydig cells: 13.4;Peritubular cells: 17.7;Sertoli cells: 13.1;Smooth muscle cells: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 25.5;SH-SY5Y: 28.5;SK-MEL-30: 31.7;U-138 MG: 38.7;U-2 OS: 40.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA035079 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035079: AB_10670287" "unprognostic (2.12e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (2.29e-1)" "unprognostic (2.92e-1)" "unprognostic (7.68e-2)" "unprognostic (7.87e-2)" "unprognostic (8.27e-2)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.38e-3)" "unprognostic (3.18e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (4.28e-4)" 15.1 5.4 2.4 1.9 2.6 0.4 10.7 0.5 3.3 19.1 4.1 10.0 1.3 22.4 0.5 3.6 15.5 3.6 10.3 2.1 3.9 10.6 3.6 23.2 1.3 5.1 3.2 20.2 4.0 0.4 5.4 3.7 2.2 15.5 0.3 0.1 4.6 4.5 3.1 10.1 6.0 2.2 2.0 9.4 7.8 2.7 4.7 0.2 11.8 0.4 0.2 13.3 13.2 1.3 0.7 0.4 5.8 10.1 3.4 4.8 2.3 25.5 10.8 6.2 3.3 0.1 0.1 0.4 14.6 12.7 0.4 0.2 3.4 0.1 0.7 0.9 21.6 2.1 0.5 4.9 21.3 0.0 1.1 8.2 0.1 3.0 1.5 3.0 3.0 0.1 0.2 0.2 2.2 1.1 0.0 0.5 7.8 0.0 3.3 0.6 16.1 0.0 0.1 0.1 2.5 28.5 0.1 0.0 31.7 1.1 0.9 0.1 3.7 38.7 40.7 1.0 5.9 1.2 0.5 0.4 0.1 0.5 19.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 2.6 0.5 3.3 2.1 3.9 5.1 3.2 2.2 2.0 4.7 1.3 3.6 0.0 0.0 1.6 0.1 2.8 1.6 0.7 0.0 2.9 0.3 0.9 44.8 0.0 0.3 0.0 2.1 0.4 0.3 0.1 0.0 0.0 0.3 2.6 8.9 10.5 0.0 0.0 1.9 0.0 1.6 21.2 1.5 1.0 0.0 0.6 3.9 0.7 0.7 0.0 5.2 0.2 0.0 0.8 2.4 0.5 13.4 0.4 3.6 6.5 0.0 0.3 1.0 3.0 1.1 0.0 0.1 17.7 0.2 7.1 0.0 0.2 4.2 0.8 13.1 1.4 19.5 1.1 0.7 0.3 2.7 0.4 1.2 2.1 0.2 0.6 SCEL "FLJ21667, MGC22531" ENSG00000136155 Sciellin O95171 13 77535674-77645263 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 385.5;skin 1: 302.7" "Cell type enriched" "Detected in many" 12 "Alveolar cells type 1: 679.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 28.6;HaCaT: 54.6;HBEC3-KT: 25.3;OE19: 74.2;RPTEC TERT1: 107.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA039737, HPA040154" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA039737: AB_10805485, HPA040154: AB_10795359" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.91e-2)" "unprognostic (4.54e-2)" "unprognostic (6.62e-2)" "unprognostic (3.51e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (1.24e-4)" "unprognostic (4.57e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.81e-1)" "unprognostic (2.82e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (1.73e-5)" 3.1 0.1 0.0 0.1 0.1 0.1 19.5 0.1 0.1 69.9 0.0 1.1 0.0 0.1 0.1 385.5 0.3 0.1 0.1 0.0 0.0 0.4 0.1 59.8 0.0 0.1 0.2 0.2 0.2 0.3 0.5 0.8 0.2 0.1 2.0 0.1 57.8 0.0 1.5 302.7 0.1 0.0 0.1 0.0 0.6 2.3 0.1 0.5 2.2 0.0 76.8 0.1 121.6 0.2 16.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 0.0 1.8 0.0 0.0 54.6 0.0 25.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 74.2 14.9 0.0 0.0 0.0 107.2 0.0 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.2 0.1 679.5 31.6 0.0 0.0 10.7 0.1 12.9 0.0 0.0 0.0 0.0 0.2 0.0 49.7 0.0 0.0 0.3 0.0 0.7 0.0 3.2 6.6 0.7 0.1 0.2 0.0 0.0 0.2 0.2 0.0 2.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 7.8 8.2 0.0 1.1 20.9 0.0 0.3 1.8 0.0 0.0 1.6 0.0 1.0 1.7 45.5 0.2 0.0 0.0 0.1 0.0 0.1 7.1 0.0 0.0 0.0 1.2 7.9 5.0 48.8 55.8 0.1 0.3 0.8 0.1 2.7 SCHIP1 SCHIP-1 ENSG00000151967 "Schwannomin interacting protein 1" P0DPB3 3 159839861-159897360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 81.0;choroid plexus: 28.9;heart muscle: 80.4;skeletal muscle: 101.3;tongue: 92.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.2;Horizontal cells: 15.2;Skeletal myocytes: 7.0" "Cancer enriched" "Detected in single" 7 "glioma: 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.9" "Group enriched" "Detected in many" 46 "dendritic cells: 6.9;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "AF22: 27.0;AN3-CA: 49.2;HUVEC TERT2: 58.3;NTERA-2: 29.8;SH-SY5Y: 167.0" "HPA003243, HPA069824" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cell Junctions, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA003243: AB_1079877, HPA069824: AB_2732142" "unprognostic (1.07e-1)" "unprognostic (3.27e-2)" "unprognostic (1.37e-2)" "unprognostic (2.36e-5)" "prognostic favorable (2.80e-4)" "unprognostic (6.25e-2)" "unprognostic (4.56e-3)" "unprognostic (1.11e-1)" "unprognostic (7.81e-2)" "unprognostic (1.38e-1)" "unprognostic (6.45e-3)" "unprognostic (4.67e-2)" "unprognostic (2.12e-1)" "unprognostic (4.66e-4)" "unprognostic (2.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.96e-1)" 6.1 2.9 46.5 0.2 56.3 0.8 1.2 52.6 55.0 2.5 28.9 11.1 1.0 3.9 0.7 3.4 2.3 1.9 80.4 50.0 48.7 2.5 0.7 2.9 0.5 51.0 48.2 0.5 0.4 0.2 11.8 10.9 52.6 5.6 1.1 3.6 1.9 1.4 101.3 0.4 3.6 5.4 55.6 4.8 4.6 1.9 46.9 0.8 0.8 92.8 0.2 0.7 1.2 81.0 0.1 0.0 27.0 49.2 0.0 0.2 0.0 0.2 0.1 0.1 1.1 0.0 0.0 0.0 1.7 0.0 1.3 0.0 0.0 2.4 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.7 1.1 0.3 11.2 0.4 58.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 29.8 0.0 0.0 0.0 5.5 0.0 1.3 0.0 0.0 167.0 0.0 0.0 0.2 7.0 0.0 3.1 10.9 0.6 1.5 0.4 2.5 2.1 0.0 0.0 0.7 2.0 1.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 46.5 56.3 52.6 55.0 50.0 48.7 51.0 48.2 52.6 55.6 46.9 81.0 4.5 6.4 1.7 0.0 0.1 0.4 4.8 2.5 1.2 5.4 0.6 0.8 14.2 0.0 2.2 3.7 2.1 1.5 2.7 0.1 0.0 0.3 0.0 4.4 0.4 6.0 0.0 2.1 0.0 0.2 0.5 1.6 0.0 3.1 0.0 0.1 2.2 0.5 0.2 15.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 3.6 0.0 0.0 3.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.6 0.0 1.4 3.7 0.6 0.0 7.0 2.9 0.0 0.4 0.4 0.6 0.8 0.2 0.2 0.0 1.4 SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027200-41242154 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 125.4;Excitatory neurons: 161.3;Inhibitory neurons: 213.0;Microglial cells: 102.1;Oligodendrocyte precursor cells: 154.3;Oligodendrocytes: 77.9;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: AB_2797246" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (1.98e-2)" "unprognostic (8.77e-2)" "unprognostic (8.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.40e-1)" "unprognostic (7.38e-2)" "unprognostic (9.47e-2)" "unprognostic (1.63e-1)" "unprognostic (8.08e-2)" "prognostic favorable (5.80e-4)" 22.0 24.0 15.2 11.3 15.9 17.8 23.2 16.5 18.1 32.0 18.6 54.6 12.7 35.4 20.5 14.0 33.1 15.8 39.3 16.1 16.9 29.8 19.7 20.6 10.4 13.6 14.7 36.3 40.1 34.7 27.6 11.0 13.1 40.4 17.0 21.0 27.5 30.7 44.9 13.3 23.4 24.6 12.2 15.5 32.5 32.8 16.7 16.6 24.1 34.2 10.5 38.9 21.3 14.1 19.5 12.8 29.9 27.5 13.4 25.4 0.1 15.4 26.7 25.2 26.0 12.3 24.6 35.4 11.4 28.1 21.1 4.8 23.3 20.6 21.6 24.7 17.8 16.6 17.7 31.2 58.2 35.7 26.2 27.7 20.5 16.7 40.2 30.5 25.7 43.3 15.7 26.8 25.0 10.6 36.0 30.8 27.7 16.4 13.5 39.3 31.3 21.0 20.4 24.1 21.0 22.5 26.7 21.1 22.1 20.2 18.8 90.7 19.0 26.3 20.4 16.4 28.5 27.1 16.2 38.6 16.5 31.5 24.4 0.6 0.6 1.2 1.6 1.1 2.0 2.4 1.9 1.5 1.9 1.1 1.3 1.1 0.0 1.6 0.2 3.9 1.4 0.9 15.2 15.9 16.5 18.1 16.1 16.9 13.6 14.7 13.1 12.2 16.7 14.1 7.1 9.6 10.8 125.4 9.4 6.6 25.8 11.5 26.7 17.0 16.4 17.0 14.9 18.6 7.4 12.9 16.7 7.3 10.8 7.2 1.9 11.4 9.4 7.2 13.8 9.6 8.4 16.0 161.3 21.3 3.3 11.4 15.3 13.1 5.1 11.9 8.9 7.3 6.2 8.4 213.0 7.4 8.2 3.3 6.5 12.4 16.4 3.2 8.8 102.1 2.7 6.9 2.1 154.3 77.9 12.4 6.2 18.0 20.2 23.3 10.4 18.1 5.8 14.2 19.7 11.9 10.3 54.3 26.1 6.1 3.7 4.8 7.4 3.5 12.4 14.5 SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 409.9;Inhibitory neurons: 494.6;Oligodendrocyte precursor cells: 692.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 6.1;Hep G2: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" 0.0 0.0 4.2 0.0 4.2 0.0 0.0 2.1 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.1 6.9 0.0 0.0 1.4 0.0 14.2 6.2 0.0 0.0 0.0 2.0 0.0 18.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.9 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 2.1 24.7 2.1 6.9 14.2 6.2 18.5 2.2 10.9 10.9 0.0 6.4 33.9 27.4 0.0 0.0 0.0 0.0 0.0 47.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.5 0.0 0.3 1.8 0.0 409.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 494.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 18.7 0.0 2.8 0.0 692.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "heart muscle: 42.8" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 77.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "LHCN-M2: 27.6;RH-30: 22.8" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 5.4" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" 0.2 0.1 1.9 0.1 1.2 0.2 0.2 0.0 0.7 1.7 0.0 0.2 0.2 0.7 0.0 0.1 0.3 0.1 42.8 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.2 0.0 0.3 0.1 2.0 0.2 0.5 1.6 0.1 0.2 0.3 0.2 0.1 0.1 0.3 2.6 0.0 0.2 1.0 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.4 0.1 0.0 0.2 3.6 0.0 0.0 0.0 1.0 0.5 2.7 0.0 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.4 0.0 2.1 2.8 0.4 0.0 0.0 27.6 1.4 0.0 0.0 2.6 0.0 0.0 0.0 22.8 0.0 0.0 3.2 0.4 3.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.7 0.2 1.5 0.0 0.7 0.0 0.2 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.7 0.0 0.3 77.1 0.0 0.1 0.0 14.6 0.2 0.0 0.0 0.0 0.1 1.2 0.1 3.2 2.8 0.0 0.0 0.5 0.0 0.3 3.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 6.3 0.3 0.6 0.2 0.0 3.7 0.0 0.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.9 0.0 7.3 3.1 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.4 SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 35.0" "Group enriched" "Detected in many" 8 "Excitatory neurons: 336.7;Inhibitory neurons: 280.1;Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 35.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.7;ASC TERT1: 13.5;WM-115: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" 0.2 1.0 5.6 0.4 8.9 0.7 0.5 2.5 35.0 0.4 0.0 0.7 0.2 0.4 0.7 0.1 0.2 0.9 0.1 11.4 0.2 0.9 2.6 0.1 0.4 4.2 0.0 0.5 1.6 0.5 6.7 0.1 3.8 0.6 0.9 7.9 0.6 0.2 0.3 0.3 0.2 0.1 0.0 0.6 1.0 1.7 2.4 0.5 0.5 0.1 0.2 0.2 0.2 11.5 1.7 1.3 13.7 0.2 1.8 13.5 0.3 8.0 12.5 9.1 8.5 2.8 1.6 0.4 1.9 9.9 4.4 0.1 2.3 0.0 10.5 1.6 0.8 0.1 0.3 0.3 0.1 0.2 1.1 1.8 0.0 6.5 1.4 3.4 9.8 3.5 0.2 0.2 5.5 1.0 2.5 0.2 4.9 0.9 4.8 0.1 0.7 0.0 0.0 0.5 5.6 2.2 4.5 2.1 0.3 2.1 0.4 0.2 2.8 8.9 6.3 3.3 5.2 0.2 0.1 0.0 1.8 1.9 13.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 5.6 8.9 2.5 35.0 11.4 0.2 4.2 0.0 3.8 0.0 2.4 11.5 1.2 0.0 0.0 27.1 0.0 0.0 0.5 0.0 3.4 16.7 2.6 1.8 1.4 1.5 0.0 0.0 10.4 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.7 1.3 11.4 0.0 336.7 0.5 0.0 0.1 3.1 0.0 0.0 0.7 1.1 4.3 0.0 5.0 280.1 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 20.6 0.0 4.7 0.0 104.5 14.2 0.7 0.5 0.7 0.0 0.4 0.0 0.7 0.0 11.2 0.0 0.4 0.3 3.8 10.2 0.1 0.0 0.0 0.3 0.0 0.9 0.3 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT1 by virus, Inhibition of host STAT2 by virus, Viral immunoevasion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: AB_2238926, CAB022081: , HPA023557: AB_2671238, HPA064312: AB_2685242" "unprognostic (1.24e-1)" "unprognostic (1.94e-2)" "unprognostic (7.78e-2)" "unprognostic (8.95e-2)" "unprognostic (3.77e-1)" "unprognostic (3.96e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (8.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.16e-3)" "unprognostic (3.46e-3)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" 18.7 17.1 11.5 7.2 10.8 5.6 23.6 6.0 10.4 45.6 0.0 32.3 9.1 24.7 0.9 100.5 26.0 3.4 24.6 8.7 2.7 27.7 25.4 21.3 4.0 10.7 8.1 23.0 38.8 5.2 24.8 5.0 5.9 28.4 3.4 1.0 40.2 5.2 54.3 68.3 26.5 2.0 4.9 22.9 30.0 26.4 9.0 3.0 24.6 1.7 3.9 27.8 52.6 15.3 55.7 33.1 12.7 20.5 5.1 6.9 33.0 30.9 5.3 11.2 9.1 15.3 29.8 24.2 39.7 7.2 4.6 52.4 7.9 32.9 1.7 30.8 58.5 24.6 30.5 26.1 10.8 13.0 14.8 5.1 29.9 9.4 5.5 5.1 11.5 19.8 42.2 6.4 7.5 93.0 38.1 26.9 15.7 25.0 55.1 44.5 10.6 25.0 5.6 45.5 29.6 27.1 31.4 30.5 33.6 4.5 41.5 28.2 25.7 10.1 64.1 25.2 44.7 31.6 31.0 23.8 13.1 9.5 19.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.5 10.8 6.0 10.4 8.7 2.7 10.7 8.1 5.9 4.9 9.0 15.3 12.3 0.0 9.9 33.0 4.4 8.5 5.0 10.2 13.6 11.3 16.8 17.0 11.1 11.5 8.3 14.7 14.6 11.0 9.7 28.7 3.9 8.6 1.5 14.0 7.7 7.8 13.8 13.7 5.0 9.4 6.3 7.3 29.6 27.3 0.0 17.9 3.6 8.8 6.5 5.0 6.2 17.8 18.3 6.0 4.1 0.7 9.0 6.6 8.8 6.5 5.0 10.0 5.2 12.1 15.2 11.5 22.8 9.8 5.6 9.3 16.9 4.5 9.9 16.0 13.1 12.0 8.7 9.4 10.0 19.9 10.7 5.1 7.3 8.0 23.2 7.1 SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 959.8;Melanocytes: 889.4" "Cancer enriched" "Detected in all" 4 "melanoma: 244.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1908.0" "Group enriched" "Detected in all" 5 "granulocytes: 1908.0;monocytes: 562.9" "Cell line enhanced" "Detected in many" "HHSteC: 787.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: AB_1857712" "unprognostic (2.39e-2)" "unprognostic (3.34e-2)" "unprognostic (1.84e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (2.60e-3)" "unprognostic (7.14e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "unprognostic (5.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.92e-1)" 228.5 126.4 94.1 160.8 111.8 245.6 167.1 102.0 130.1 160.9 112.2 119.6 83.1 109.8 83.6 88.8 95.7 194.8 120.6 103.7 112.6 126.6 174.0 223.9 121.2 113.7 103.8 89.1 80.8 132.9 45.8 264.3 113.5 70.8 134.7 26.8 124.9 78.3 65.9 84.8 92.8 151.2 107.4 203.0 130.0 41.1 110.8 129.9 120.7 113.7 92.8 248.8 91.9 123.7 123.5 185.9 194.2 101.4 711.7 607.1 86.1 122.9 439.6 175.3 228.9 74.8 250.7 0.4 194.8 166.4 321.2 49.7 106.0 142.4 215.7 22.6 91.3 184.3 156.0 60.6 787.9 47.7 287.1 417.9 188.1 176.5 525.2 273.0 428.0 125.2 92.3 104.6 403.4 32.4 104.1 55.9 122.2 478.6 52.3 49.6 59.4 24.3 282.1 127.0 84.9 153.5 133.8 56.1 630.0 213.8 51.0 127.9 382.3 168.8 72.5 200.8 81.5 31.4 45.6 74.8 428.9 0.5 155.1 777.4 562.9 528.1 61.2 349.6 78.0 69.4 82.0 67.3 251.8 61.0 103.9 80.2 1908.0 42.6 329.1 69.9 103.0 453.2 94.1 111.8 102.0 130.1 103.7 112.6 113.7 103.8 113.5 107.4 110.8 123.7 382.7 211.5 115.9 26.8 170.3 338.7 321.2 312.5 108.1 10.8 86.7 54.6 70.6 88.6 181.3 206.0 16.7 284.3 220.2 192.9 225.0 392.9 7.8 110.9 87.0 412.7 112.3 116.6 18.5 291.6 756.8 308.1 162.1 120.5 396.9 62.9 378.3 101.9 782.5 15.2 23.7 180.3 248.2 552.1 959.8 15.9 233.9 626.0 889.4 71.2 312.4 94.3 51.5 21.6 16.3 297.9 152.9 159.9 65.1 307.4 78.4 211.2 169.8 11.1 98.6 82.7 177.4 14.8 8.4 73.3 173.2 483.0 256.2 117.0 129.2 457.6 SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 141.8;intestine: 136.9;stomach 1: 101.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 782.5;Pancreatic endocrine cells: 755.4;Paneth cells: 948.5;Proximal enterocytes: 470.3;Urothelial cells: 641.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.6;OE19: 57.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" 7.3 3.4 19.9 10.1 20.7 0.7 6.9 16.3 24.3 25.8 15.2 85.8 136.9 5.7 9.0 141.8 4.3 41.8 4.6 19.6 20.2 16.0 18.1 20.9 1.3 17.2 17.9 3.5 15.2 2.5 3.9 3.3 17.4 6.5 55.5 1.0 29.8 2.5 2.8 62.9 133.0 3.6 16.9 3.1 101.8 5.6 20.3 1.5 14.6 1.4 13.7 38.2 49.9 18.0 10.9 0.5 1.4 0.5 5.8 5.1 0.9 3.2 6.3 2.8 2.7 2.3 18.6 1.1 2.1 1.2 2.0 8.2 0.5 15.5 1.4 0.4 1.0 0.9 0.6 1.5 5.8 1.1 1.2 1.8 10.8 2.2 2.2 6.0 9.6 2.0 1.5 0.7 1.1 2.6 1.7 3.0 1.3 57.3 0.7 1.6 0.7 2.2 1.2 14.4 2.4 1.9 1.5 9.3 3.6 0.6 0.4 0.9 6.5 1.5 0.6 2.8 1.2 2.8 2.7 1.1 0.7 4.1 0.9 0.1 0.8 1.9 0.9 0.3 0.7 0.2 1.2 0.9 1.0 0.4 1.0 1.8 0.8 0.9 0.6 0.7 2.3 0.7 19.9 20.7 16.3 24.3 19.6 20.2 17.2 17.9 17.4 16.9 20.3 18.0 15.6 16.0 4.2 0.0 4.1 55.7 112.0 198.1 3.4 1.0 4.9 4.8 0.8 72.9 172.6 16.5 0.0 1.8 1.0 782.5 27.4 114.5 17.1 25.8 11.7 14.1 35.9 0.0 0.0 209.7 1.1 4.6 201.8 85.4 8.9 1.0 7.1 5.1 0.9 1.7 0.0 150.8 156.6 1.9 6.4 1.9 1.5 1.8 8.8 0.0 2.3 1.0 2.1 0.0 0.0 755.4 948.5 0.0 0.7 107.0 470.3 1.8 89.6 0.9 0.0 1.7 9.9 5.0 7.6 31.1 95.6 1.6 3.5 2.0 109.2 641.9 SDE2 "C1orf55, FLJ35382" ENSG00000143751 "SDE2 telomere maintenance homolog" Q6IQ49 1 225982702-225999343 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028467, HPA031255, HPA031256" Approved Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Golgi apparatus, Plasma membrane, Cytosol" "HPA028467: AB_10599192, HPA031255: AB_10601462, HPA031256: AB_10603568" "unprognostic (9.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (9.59e-2)" "unprognostic (2.68e-1)" "unprognostic (3.63e-2)" "unprognostic (1.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.01e-2)" "unprognostic (1.41e-3)" "unprognostic (3.90e-2)" "unprognostic (3.51e-1)" "unprognostic (3.98e-2)" "unprognostic (3.84e-2)" 17.4 8.5 5.5 11.3 7.0 32.9 11.8 6.4 6.6 9.0 4.8 8.3 9.0 11.8 7.8 9.6 7.4 10.5 7.7 4.9 6.0 9.2 14.6 9.2 12.4 6.9 6.6 10.2 9.6 11.1 4.4 11.8 6.6 9.8 9.1 5.1 6.7 7.3 12.7 10.8 9.0 9.8 6.6 10.4 7.7 8.3 6.1 22.8 12.5 9.6 10.6 11.6 7.8 8.4 13.1 9.3 14.9 15.9 10.2 11.3 18.5 13.7 12.9 18.4 14.0 13.7 14.7 19.2 20.9 11.6 7.2 16.5 18.9 11.9 22.2 14.7 15.3 21.1 7.9 12.7 18.6 21.0 24.6 12.5 16.9 19.6 24.6 10.3 12.8 22.6 39.3 22.6 13.7 3.8 29.5 16.6 20.8 20.2 9.8 24.4 19.1 24.9 11.1 9.2 13.3 22.0 15.6 16.9 26.3 11.9 16.6 25.4 12.7 15.6 11.0 20.3 30.4 13.4 10.3 23.4 16.1 12.9 31.5 21.8 6.3 5.9 8.0 6.4 10.8 8.0 8.1 7.8 7.1 7.0 8.1 7.7 18.5 13.5 7.9 8.1 6.7 6.9 5.5 7.0 6.4 6.6 4.9 6.0 6.9 6.6 6.6 6.6 6.1 8.4 36.0 28.9 22.6 4.2 39.9 43.6 17.2 11.2 29.0 6.2 19.8 13.6 9.4 2.8 20.1 9.2 0.0 9.6 29.3 14.3 15.6 6.5 72.8 24.8 15.1 24.8 17.4 56.2 4.7 7.1 10.2 17.8 13.3 35.9 35.5 9.7 12.8 20.6 11.1 15.2 5.0 10.8 16.2 16.4 28.8 20.4 9.9 27.0 19.6 1.9 7.4 12.6 10.3 4.5 8.6 9.7 9.4 6.4 26.6 14.2 9.5 12.7 12.7 8.9 6.6 28.8 23.9 23.9 14.4 26.5 59.1 14.2 23.2 21.0 9.9 18.2 SDHAF2 "C11orf79, FLJ20487, PGL2, SDH5" ENSG00000167985 "Succinate dehydrogenase complex assembly factor 2" Q9NX18 11 61430042-61446733 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039464, HPA039732" Supported Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Mitochondria, Cytosol" Nucleoli "HPA039464: AB_10962146, HPA039732: AB_10962868" "unprognostic (5.31e-2)" "unprognostic (1.12e-2)" "unprognostic (3.13e-1)" "unprognostic (1.30e-2)" "unprognostic (1.40e-1)" "unprognostic (6.71e-2)" "unprognostic (1.98e-3)" "unprognostic (9.06e-2)" "unprognostic (2.17e-1)" "unprognostic (2.09e-3)" "unprognostic (4.21e-3)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (1.45e-1)" "unprognostic (4.48e-2)" 27.5 37.1 36.2 26.4 37.4 45.6 28.9 37.9 38.2 23.8 37.4 27.2 24.7 23.8 34.8 28.8 28.7 25.5 40.4 35.9 40.2 36.5 46.4 23.8 39.9 37.9 37.6 26.9 24.0 32.9 41.0 24.9 37.9 29.0 29.1 23.4 26.3 20.9 38.9 26.3 27.0 26.9 37.7 34.7 27.6 22.1 38.0 38.0 28.6 44.7 41.6 32.8 21.7 39.2 45.0 58.4 36.5 25.1 57.2 52.2 27.0 33.3 58.0 48.9 41.8 52.8 46.8 42.3 58.4 55.6 62.8 45.4 45.4 51.4 56.6 60.4 39.7 33.2 35.5 71.9 52.8 41.4 48.1 55.6 58.7 50.2 45.8 35.3 80.8 43.5 42.2 50.9 63.5 86.0 49.2 89.3 56.1 47.0 78.6 45.9 45.9 76.6 63.7 57.9 36.9 40.6 46.9 53.5 99.0 38.5 83.0 40.2 53.3 45.0 32.7 54.3 37.5 31.2 51.2 54.7 43.4 37.3 46.0 125.3 68.8 126.6 82.5 64.5 103.1 89.7 93.0 91.7 55.9 84.8 101.5 97.5 97.9 97.9 53.3 63.3 126.7 78.6 36.2 37.4 37.9 38.2 35.9 40.2 37.9 37.6 37.9 37.7 38.0 39.2 32.8 35.3 33.2 11.1 28.9 20.6 34.6 53.7 10.2 14.0 27.9 35.1 22.3 14.3 33.5 29.5 6.2 77.0 41.9 29.5 54.8 55.3 15.8 19.3 21.7 36.5 34.2 30.3 13.2 60.3 51.4 28.4 16.8 19.0 32.3 22.2 42.5 42.3 52.7 15.2 13.3 31.4 59.0 36.5 22.8 17.8 31.4 29.7 44.4 8.4 66.4 49.4 69.0 16.6 18.1 62.9 34.9 30.9 16.3 30.8 34.0 51.9 31.5 19.7 32.9 17.3 27.2 23.1 25.8 10.9 22.4 99.6 41.5 45.1 27.6 38.8 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SEC16B "LZTR2, PGPR-p117, RGPR, Sec16S" ENSG00000120341 "SEC16 homolog B, endoplasmic reticulum export factor" Q96JE7 1 177923956-177984303 "Predicted intracellular proteins" "ER-Golgi transport, Peroxisome biogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.4;liver: 36.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.3;Late spermatids: 50.4;Proximal enterocytes: 34.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.6;CAPAN-2: 7.2;EFO-21: 5.4;HDLM-2: 5.8;Karpas-707: 4.8;RPMI-8226: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054292, HPA072913" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Actin filaments" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "Actin filaments" "HPA054292: AB_2682439, HPA072913: AB_2732213" "unprognostic (2.31e-1)" "unprognostic (1.90e-1)" "unprognostic (6.78e-3)" "unprognostic (6.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-2)" "unprognostic (1.50e-2)" "unprognostic (4.76e-3)" "unprognostic (2.43e-1)" "unprognostic (7.34e-4)" "unprognostic (6.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" 4.0 2.5 0.5 1.1 1.1 0.3 3.2 0.0 2.9 3.0 0.0 3.6 28.0 3.5 2.0 2.0 3.5 4.3 2.6 0.8 0.1 3.4 36.4 2.4 1.1 0.0 0.3 4.2 9.0 0.5 1.4 0.8 0.1 1.6 4.0 5.7 3.6 2.1 9.3 2.7 28.4 2.7 0.0 5.8 8.7 1.4 0.3 0.4 2.1 3.1 0.9 1.4 1.1 1.2 1.9 1.5 0.1 1.5 1.9 6.6 0.0 1.5 0.5 0.1 0.7 1.0 7.2 0.6 5.4 1.2 0.1 0.0 0.4 0.2 0.0 5.8 0.1 0.0 0.0 3.4 0.1 0.1 0.0 3.8 0.5 0.2 0.0 0.2 2.2 0.0 0.0 4.8 3.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 6.5 0.1 0.1 0.6 1.2 0.1 0.2 0.8 0.0 0.1 1.3 0.7 1.0 0.2 0.6 0.0 1.5 0.7 0.1 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 2.9 0.8 0.1 0.0 0.3 0.1 0.0 0.3 1.2 7.7 0.0 2.0 2.9 0.7 0.3 0.3 0.4 1.8 1.3 6.3 1.8 0.5 7.2 1.9 1.8 2.1 0.5 0.0 0.9 0.0 0.6 10.1 2.3 1.6 3.9 3.6 0.0 15.8 1.1 0.0 1.9 9.2 2.7 1.3 1.9 3.6 66.3 0.6 11.8 4.8 4.6 0.0 3.2 0.4 50.4 2.5 0.7 1.8 3.7 0.6 1.4 0.0 1.0 1.3 1.1 5.2 1.2 2.9 0.1 34.8 3.1 3.3 4.7 0.0 2.7 1.0 0.3 0.8 0.6 1.0 0.0 0.3 0.1 5.4 0.2 SEC31B "DKFZP434M183, SEC31B-1, SEC31L2" ENSG00000075826 "SEC31 homolog B, COPII coat complex component" Q9NQW1 10 100486646-100519864 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Bipolar cells: 32.2;Cone photoreceptor cells: 39.6;Excitatory neurons: 38.1;Horizontal cells: 40.4;Inhibitory neurons: 40.7;Oligodendrocyte precursor cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.1;JURKAT: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035882, HPA040819, HPA060052" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles, Cytosol" "HPA035882: AB_10795246, HPA040819: AB_10794151, HPA060052: " "unprognostic (1.23e-1)" "unprognostic (3.13e-3)" "unprognostic (3.39e-3)" "unprognostic (1.03e-2)" "unprognostic (4.85e-2)" "unprognostic (1.42e-3)" "unprognostic (1.97e-3)" "unprognostic (6.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.10e-4)" "unprognostic (8.23e-3)" "prognostic unfavorable (6.41e-7)" "unprognostic (2.31e-2)" "unprognostic (2.54e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-4)" 2.2 1.5 2.0 1.1 2.0 2.5 2.0 2.3 2.9 2.6 1.2 2.5 0.3 2.1 1.0 0.8 2.6 0.8 2.8 1.8 1.9 2.2 2.0 1.7 1.6 1.9 1.7 2.8 0.6 1.7 3.7 0.7 1.8 2.3 0.8 1.5 1.6 0.8 5.9 1.3 2.3 0.8 1.5 3.0 1.7 2.7 1.9 2.9 2.0 8.3 1.3 1.8 1.5 2.2 0.1 0.0 2.0 0.5 0.6 1.0 0.1 0.4 0.9 0.2 0.6 0.1 0.0 0.4 0.6 0.0 0.1 0.0 1.1 0.2 0.5 2.5 0.5 1.0 1.5 0.2 0.9 0.8 0.8 1.8 1.0 0.1 1.2 9.1 0.3 8.9 0.1 1.3 0.0 0.0 1.4 2.3 0.0 0.2 0.4 2.0 0.0 0.9 0.6 0.0 0.1 0.7 0.2 0.0 0.4 1.5 0.4 0.2 0.0 0.1 0.2 0.1 0.1 0.9 0.5 0.6 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.0 2.3 2.9 1.8 1.9 1.9 1.7 1.8 1.5 1.9 2.2 2.5 6.4 4.5 28.7 2.4 1.1 0.9 1.7 1.2 32.2 2.9 2.0 8.0 4.3 2.3 11.0 39.6 1.2 4.5 3.8 0.0 0.4 2.3 1.3 3.4 2.6 5.4 0.4 38.1 0.2 0.3 2.4 3.1 1.6 1.3 7.7 2.9 6.1 2.2 40.4 40.7 3.3 0.0 4.8 1.7 1.7 3.4 3.5 1.8 7.5 5.2 3.6 1.0 32.6 21.5 0.2 2.0 4.1 2.5 1.2 2.4 1.0 2.2 5.8 0.0 1.9 2.2 7.7 3.2 1.8 1.1 0.8 4.6 4.7 4.0 1.1 SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 92.2;Breast myoepithelial cells: 93.5;Fibroblasts: 109.6;Ionocytes: 91.6;Oligodendrocytes: 223.7;Respiratory ciliated cells: 103.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.6" "Cell line enhanced" "Detected in many" "GAMG: 252.7;RT4: 238.3;T-47d: 267.0;U-2197: 349.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 13000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" 53.8 9.5 4.9 12.7 8.1 0.8 57.3 9.1 5.5 53.0 2.6 38.4 10.6 42.7 23.1 20.5 15.4 30.0 22.1 11.0 12.7 10.0 1.3 18.4 1.0 15.0 8.0 48.5 2.6 0.8 3.7 6.0 17.5 66.6 31.3 1.0 27.3 42.3 19.3 17.9 14.1 44.4 10.0 22.2 20.6 12.9 8.4 1.4 1.8 34.3 1.1 69.8 14.4 12.8 6.6 77.0 156.4 0.6 35.2 82.5 0.3 51.8 59.7 25.9 32.5 12.4 144.7 0.0 2.1 17.7 252.7 31.2 0.7 47.0 42.4 0.1 15.8 9.9 63.6 0.7 41.3 0.7 0.2 36.1 32.3 63.6 62.0 220.2 0.5 0.0 0.5 0.1 46.4 113.7 0.2 0.3 1.4 22.2 12.2 0.1 75.5 1.2 142.9 238.3 0.8 82.4 145.7 38.9 9.5 66.3 267.0 0.2 125.2 140.1 64.2 349.2 93.9 1.2 0.0 0.1 52.8 0.0 142.3 49.6 5.7 0.9 0.0 2.4 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 2.6 0.0 1.9 3.3 0.0 1.7 4.9 8.1 9.1 5.5 11.0 12.7 15.0 8.0 17.5 10.0 8.4 12.8 7.4 9.6 8.9 3.3 0.3 26.4 41.8 92.2 10.8 0.3 15.8 93.5 38.2 1.5 39.8 7.3 6.2 0.5 1.7 56.1 1.9 3.8 0.5 20.3 11.9 7.7 6.0 4.6 41.7 6.6 1.3 109.6 17.9 34.4 5.1 13.2 1.1 0.0 8.8 0.0 16.7 15.7 91.6 3.1 14.9 2.3 7.8 9.0 55.2 20.6 8.3 1.5 1.0 3.0 223.7 68.2 12.4 52.3 0.0 53.7 12.5 0.4 103.0 0.6 0.0 38.8 17.3 0.7 2.7 3.0 18.9 0.3 1.5 9.9 30.4 70.0 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.5;Inhibitory neurons: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064095, HPA065969" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA064095: AB_2732710, HPA065969: AB_2685590" "unprognostic (9.69e-2)" "unprognostic (8.88e-3)" "unprognostic (1.58e-2)" "prognostic unfavorable (5.94e-5)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.23e-2)" "unprognostic (1.61e-3)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (6.53e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.74e-6)" "unprognostic (2.60e-2)" "unprognostic (8.08e-2)" "prognostic favorable (6.94e-4)" "unprognostic (4.69e-2)" 3.2 2.3 5.4 0.9 7.0 0.4 3.2 3.2 8.2 4.1 0.1 2.5 0.5 3.6 1.7 1.3 3.3 0.8 2.7 8.0 6.3 3.5 1.0 2.5 1.5 4.2 2.1 5.3 2.6 3.0 7.2 0.9 3.9 3.1 1.0 4.7 2.7 1.4 1.4 1.9 2.1 1.6 1.5 2.6 2.2 4.1 8.1 1.2 3.1 1.3 1.4 2.6 3.2 3.8 6.1 3.4 3.7 5.5 5.8 3.3 2.6 3.9 8.9 7.4 6.5 1.4 3.3 2.3 5.0 6.2 14.4 1.9 6.7 5.7 7.5 5.3 7.0 4.4 1.4 3.8 2.3 1.0 5.4 2.6 6.0 4.9 2.4 14.1 2.9 4.4 0.2 0.2 4.8 2.1 3.3 0.8 2.6 2.7 4.0 0.0 5.4 0.0 6.0 2.6 2.9 5.8 7.0 1.8 6.5 5.0 2.6 0.7 4.9 11.5 5.8 2.9 7.1 5.2 5.6 0.3 13.4 0.3 5.6 0.3 0.1 0.7 1.9 0.0 1.2 1.1 1.1 1.7 0.0 0.8 1.1 1.3 0.3 1.0 0.2 0.0 0.9 0.8 5.4 7.0 3.2 8.2 8.0 6.3 4.2 2.1 3.9 1.5 8.1 3.8 2.2 0.0 6.5 4.9 2.7 0.4 1.8 1.8 2.2 8.8 1.8 2.5 2.4 5.7 4.8 5.5 12.5 0.8 1.4 0.7 1.9 2.1 3.2 0.6 0.6 2.2 7.2 0.8 44.5 1.6 2.4 3.3 1.5 1.0 2.5 3.0 3.3 0.6 0.8 11.8 22.7 0.6 2.0 0.0 0.7 3.7 0.9 0.7 0.0 4.7 1.5 3.3 4.1 4.5 5.8 2.7 1.4 1.5 0.7 1.3 0.4 0.3 1.3 6.7 6.6 3.1 1.4 5.6 11.2 0.5 0.4 0.4 3.5 0.5 1.0 1.6 SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 60.1;brain: 75.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.9;Hepatic stellate cells: 145.6;Horizontal cells: 138.0;Oligodendrocyte precursor cells: 138.7;Oligodendrocytes: 311.3;Syncytiotrophoblasts: 348.1" "Cancer enhanced" "Detected in all" "testis cancer: 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.3;HAP1: 52.0;NTERA-2: 115.2;SuSa: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 620000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: AB_10610423, HPA031267: " "unprognostic (3.79e-2)" "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (6.81e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (5.82e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (6.21e-3)" "unprognostic (7.32e-3)" 13.4 60.1 24.1 4.9 48.6 3.5 13.1 39.9 31.9 10.0 0.3 20.6 19.9 6.0 2.8 4.4 8.2 12.9 7.1 24.5 40.3 8.6 5.6 17.9 4.5 51.9 41.0 18.1 11.2 2.0 5.8 31.9 50.0 6.0 17.5 10.4 16.6 2.5 8.2 6.9 25.5 5.8 32.9 11.2 7.0 7.5 44.1 3.6 9.1 6.5 2.2 5.6 8.1 75.2 0.3 0.1 36.9 44.3 0.2 0.0 38.2 0.7 0.4 0.2 0.2 2.2 1.5 1.6 1.7 0.6 0.7 0.4 52.0 0.0 0.1 1.6 7.7 0.7 0.7 13.1 0.5 0.5 2.6 0.7 0.0 0.0 0.0 0.5 0.2 0.3 0.3 0.4 0.2 0.8 0.7 3.9 115.2 0.2 0.3 6.9 24.2 1.8 19.0 33.7 10.3 3.7 0.2 0.7 19.7 221.1 14.4 2.6 0.9 3.6 3.1 0.4 1.5 0.6 0.7 0.8 0.6 1.8 13.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.1 48.6 39.9 31.9 24.5 40.3 51.9 41.0 50.0 32.9 44.1 75.2 64.7 0.0 0.6 71.8 1.1 6.5 0.7 13.1 34.7 17.9 17.0 8.3 8.6 61.5 3.1 14.7 2.1 128.9 0.3 73.3 0.0 42.9 13.6 12.2 4.8 60.9 28.1 2.7 26.9 1.3 8.1 15.4 1.1 10.6 0.0 9.7 145.6 0.9 12.5 138.0 62.2 30.7 0.0 14.8 4.6 2.4 6.5 1.1 24.9 54.4 0.1 5.8 0.0 138.7 311.3 2.0 46.7 1.9 2.6 1.5 40.7 4.4 0.6 3.5 0.0 36.1 8.1 0.9 1.5 11.3 4.1 348.1 0.8 3.5 40.3 2.2 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SENP7 ENSG00000138468 "SUMO specific peptidase 7" Q9BQF6 3 101324205-101513241 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 109.6;Oligodendrocyte precursor cells: 157.3;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 44.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 44.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027259, HPA071998" Approved Supported "Nucleoplasm,Nuclear bodies,Centrosome,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Nuclear bodies, Centrosome, Cytosol" "HPA027259: AB_1856679, HPA071998: " "unprognostic (1.50e-1)" "unprognostic (6.12e-2)" "unprognostic (2.78e-2)" "unprognostic (7.31e-2)" "unprognostic (2.44e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.38e-3)" "unprognostic (9.25e-3)" "unprognostic (8.80e-2)" "unprognostic (2.24e-1)" "unprognostic (7.77e-3)" "unprognostic (1.94e-1)" "unprognostic (9.85e-2)" "unprognostic (8.08e-3)" "unprognostic (3.27e-1)" "unprognostic (9.03e-2)" "unprognostic (2.23e-2)" 15.1 9.7 9.7 13.7 12.7 24.7 16.9 21.8 11.8 15.8 9.7 12.5 7.3 26.8 14.7 7.8 16.1 14.2 9.5 9.3 12.3 11.4 8.7 12.8 23.1 13.9 11.7 26.3 12.8 16.9 10.2 19.4 14.0 12.7 10.8 26.0 8.9 11.5 11.2 20.8 12.4 14.7 10.1 16.9 14.1 9.1 11.5 20.5 17.5 11.2 17.7 11.8 11.4 20.3 9.2 6.1 29.4 16.4 5.6 8.2 5.3 5.2 3.8 8.5 10.4 4.0 8.3 7.0 7.9 5.1 7.8 9.1 9.4 4.8 17.0 13.0 2.7 12.7 5.1 5.5 4.5 7.4 12.2 6.4 8.5 4.3 9.6 7.6 12.2 13.4 10.5 17.6 8.1 6.1 13.7 8.6 6.0 4.8 6.3 15.2 8.0 6.4 10.1 5.2 11.3 8.8 4.8 4.8 6.5 15.0 8.0 9.8 10.2 11.8 7.1 3.9 5.2 12.2 7.8 16.4 4.1 9.7 9.8 44.1 5.9 5.9 5.8 5.4 7.3 6.4 7.8 5.8 4.8 9.0 10.3 7.1 17.3 9.3 6.3 4.1 6.9 6.1 9.7 12.7 21.8 11.8 9.3 12.3 13.9 11.7 14.0 10.1 11.5 20.3 44.5 16.0 24.9 78.4 33.0 9.1 8.4 7.4 21.1 48.3 14.4 12.2 21.6 2.8 18.4 16.5 20.9 5.8 30.8 5.4 5.9 8.1 4.1 33.1 48.5 28.4 13.1 18.7 62.4 5.2 2.7 23.4 21.4 34.1 37.2 28.6 32.9 10.3 8.2 52.2 109.6 6.5 12.2 20.5 9.5 4.0 18.3 19.1 10.6 80.6 13.6 16.7 35.0 157.3 134.4 6.9 4.1 19.5 23.5 4.8 7.0 8.5 27.5 33.8 46.0 29.7 23.3 22.8 19.9 13.4 9.9 2.5 41.0 21.1 5.9 6.1 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 27.9" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.6;Daudi: 22.3;SCLC-21H: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" 0.2 4.6 134.7 0.4 160.5 0.1 1.3 82.4 233.7 0.2 30.5 0.8 0.3 0.2 1.4 0.2 0.1 0.4 0.2 167.0 89.5 0.3 0.1 0.7 0.5 86.2 73.4 0.2 1.2 18.6 7.8 5.7 83.8 1.3 0.5 28.4 0.4 0.0 0.1 1.6 0.4 0.3 56.9 0.2 0.7 2.1 91.4 0.9 0.8 0.2 0.5 0.3 0.4 150.7 1.5 1.7 26.6 20.1 0.3 0.0 13.3 0.3 0.3 1.8 0.8 0.4 3.1 22.3 0.7 0.2 11.4 0.1 14.0 0.1 0.7 9.2 4.6 0.1 0.5 0.0 0.2 0.0 0.9 0.2 1.0 0.1 0.0 0.0 0.0 12.1 0.0 3.4 0.0 2.4 3.7 0.2 18.2 0.2 0.7 17.9 0.0 1.3 0.0 2.7 71.4 14.8 10.9 0.1 18.2 2.5 2.6 6.7 0.0 0.0 9.2 0.9 1.0 14.1 13.1 0.2 0.3 9.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 134.7 160.5 82.4 233.7 167.0 89.5 86.2 73.4 83.8 56.9 91.4 150.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 321.9" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 3.4;Smooth muscle cells: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.4;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "K-562: 281.6;THP-1: 75.9" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 860000 "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: AB_628240, HPA029095: AB_2672904, HPA063885: AB_2685141" "unprognostic (4.07e-2)" "unprognostic (1.47e-1)" "unprognostic (6.78e-3)" "unprognostic (1.39e-2)" "unprognostic (3.92e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (3.77e-1)" "unprognostic (5.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.88e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.87e-6)" "unprognostic (3.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (3.30e-2)" 17.7 17.7 152.8 5.7 215.6 41.0 16.4 49.2 321.9 54.1 61.9 19.8 5.2 28.1 46.2 62.1 38.8 14.7 165.4 233.6 49.3 12.7 5.2 17.4 8.4 40.9 45.2 29.3 17.0 127.3 82.7 12.0 39.4 20.1 6.3 30.3 15.9 9.9 10.8 126.5 8.8 17.3 24.7 14.3 16.3 29.1 73.1 15.9 33.4 16.2 8.1 13.5 42.8 168.6 0.4 10.6 42.0 64.0 3.9 13.1 0.3 15.8 20.1 17.9 10.5 0.7 5.6 1.5 6.1 35.8 26.0 6.0 30.2 6.0 8.8 9.6 3.4 0.7 2.4 0.2 16.2 0.8 47.2 17.4 7.4 6.0 2.5 5.1 7.5 23.1 281.6 0.6 28.2 4.2 4.6 31.2 5.4 1.0 10.4 41.4 1.3 7.2 1.3 1.4 62.3 49.2 2.4 3.5 2.8 10.2 17.3 75.9 3.0 46.4 55.6 2.0 3.2 4.5 0.0 0.4 5.8 2.2 15.2 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 5.8 0.0 0.0 0.3 0.0 6.0 152.8 215.6 49.2 321.9 233.6 49.3 40.9 45.2 39.4 24.7 73.1 168.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEPTIN7 "CDC10, CDC3, SEPT7, SEPT7A" ENSG00000122545 "Septin 7" Q16181 7 35800932-35907105 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 570.9" "Group enriched" "Detected in some" 4 "Adipocytes: 192.1;Cardiomyocytes: 227.0;Cytotrophoblasts: 171.4;dendritic cells: 196.6;Extravillous trophoblasts: 198.2;Fibroblasts: 153.5;Hofbauer cells: 191.0;Smooth muscle cells: 190.0;Syncytiotrophoblasts: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023309, HPA029524" Enhanced Approved "Nucleoli,Plasma membrane,Actin filaments,Midbody,Cytosol" Yes No 4300000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoli, Plasma membrane, Midbody, Cytosol" "HPA023309: AB_10600093, HPA029524: AB_10601573" "unprognostic (7.91e-3)" "unprognostic (6.89e-3)" "unprognostic (9.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (2.37e-4)" "unprognostic (2.00e-2)" "unprognostic (4.43e-2)" "unprognostic (7.13e-2)" "unprognostic (3.56e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (2.43e-3)" 127.1 95.1 352.6 98.8 386.1 131.0 99.5 334.3 570.9 111.5 289.5 116.4 55.7 126.5 121.5 106.6 84.1 117.5 172.1 344.1 341.6 82.9 76.9 98.6 150.9 337.4 355.9 138.2 37.0 81.1 62.6 143.5 339.1 93.9 94.8 119.5 50.3 95.5 82.9 105.0 74.9 145.2 345.1 108.3 59.4 70.3 367.7 159.0 78.2 104.3 149.7 125.0 86.9 411.9 198.1 94.3 232.0 153.2 256.7 263.1 119.3 248.6 228.6 206.7 177.0 147.7 148.9 186.2 164.2 254.9 274.9 146.3 166.3 166.4 294.0 127.8 88.4 149.8 123.4 80.8 149.4 182.7 157.7 171.7 127.1 163.8 159.4 215.6 221.0 143.3 120.1 141.9 341.6 92.8 185.6 304.3 249.7 183.1 132.6 188.3 220.9 107.6 202.6 146.1 124.3 217.4 173.5 220.1 151.8 377.1 163.1 198.7 187.3 207.2 246.7 129.9 278.5 165.9 163.4 470.2 132.4 301.2 449.3 266.8 86.0 150.1 214.8 100.1 220.7 165.6 151.5 199.6 100.8 155.5 134.4 171.2 160.9 298.7 110.5 71.0 147.4 241.7 352.6 386.1 334.3 570.9 344.1 341.6 337.4 355.9 339.1 345.1 367.7 411.9 192.1 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 227.0 0.0 0.0 0.0 0.0 171.4 196.6 0.0 0.0 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 198.2 153.5 0.0 0.0 0.0 0.0 0.0 0.0 191.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.0 0.0 0.0 0.0 0.0 124.2 30.4 0.0 0.0 0.0 SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 222.5;Urothelial cells: 254.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" 12.9 34.8 19.2 9.8 31.0 6.3 11.8 27.2 20.7 16.4 17.4 28.3 9.2 9.2 21.1 17.6 16.2 14.2 5.3 18.0 22.7 6.2 45.4 14.1 8.2 26.5 27.6 15.1 7.6 7.1 4.1 16.5 26.8 33.7 29.4 16.3 13.3 7.0 2.7 19.1 9.7 7.6 22.2 4.8 16.6 29.2 28.0 7.9 5.8 2.9 11.4 17.8 11.3 44.4 11.3 19.7 6.6 4.2 8.9 9.5 19.6 9.0 6.0 3.9 4.0 40.0 56.7 1.7 9.0 11.7 9.2 31.7 8.9 23.9 5.6 1.6 4.8 1.4 2.2 21.7 3.3 1.3 4.1 10.8 13.1 10.2 26.0 11.0 7.3 54.0 3.6 9.4 10.4 19.4 22.8 5.5 9.3 15.8 6.8 26.9 5.8 3.0 11.5 54.4 0.4 6.3 8.0 18.5 35.4 33.5 8.2 6.9 8.0 11.3 3.2 11.6 11.3 7.1 3.5 28.1 21.0 3.9 46.9 10.4 9.1 6.7 2.1 4.9 1.6 0.8 18.7 5.7 5.8 1.1 23.3 14.1 5.2 0.6 1.5 1.4 6.6 7.5 19.2 31.0 27.2 20.7 18.0 22.7 26.5 27.6 26.8 22.2 28.0 44.4 48.5 60.9 30.2 46.0 10.5 6.4 56.8 5.6 19.9 3.6 27.7 14.1 8.2 31.5 18.3 16.5 0.0 16.1 12.9 127.4 9.8 26.5 1.7 82.0 29.6 24.5 60.1 24.8 20.9 19.5 25.7 24.9 40.2 157.0 8.2 27.6 35.3 82.7 21.8 3.3 78.3 60.0 4.1 29.2 27.8 7.6 18.3 38.4 5.4 66.5 44.8 65.1 1.0 223.2 222.5 35.4 56.4 39.9 8.7 148.2 27.7 5.1 4.3 5.3 32.9 7.5 17.4 3.1 12.8 44.4 9.8 129.2 37.7 15.2 85.9 254.2 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: AB_2683607" "prognostic unfavorable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 44.7 18.5 17.8 15.1 17.7 9.7 27.3 19.3 17.3 40.5 21.2 23.5 7.3 33.0 12.6 28.1 18.8 26.7 41.0 16.6 19.4 10.1 50.1 19.2 11.7 25.0 20.3 19.6 21.9 34.7 8.8 19.1 24.7 35.1 15.3 11.5 16.2 20.6 106.6 22.7 12.1 34.8 24.6 17.0 20.1 14.4 24.5 10.1 14.1 73.7 15.9 23.4 18.2 29.2 28.4 37.2 13.0 7.8 77.1 65.9 29.6 65.7 67.3 32.4 27.1 22.7 37.2 68.0 25.5 110.5 22.4 13.9 44.3 51.3 52.4 32.8 33.0 8.9 45.5 0.8 38.4 31.9 12.9 57.7 58.6 52.1 54.6 41.2 41.7 27.8 5.5 96.1 42.3 46.8 21.0 4.6 6.4 40.8 23.9 19.7 48.4 37.3 31.5 25.3 55.3 18.5 44.7 63.5 15.3 12.6 25.3 28.0 68.8 57.1 40.7 68.6 55.2 89.6 86.8 42.2 65.9 31.1 28.0 0.5 3.9 0.2 0.3 2.0 2.7 1.0 1.1 1.1 4.4 1.2 0.4 0.2 0.9 0.2 3.2 2.1 3.7 1.2 17.8 17.7 19.3 17.3 16.6 19.4 25.0 20.3 24.7 24.6 24.5 29.2 28.7 6.4 18.8 17.3 8.9 17.2 14.5 14.1 12.5 5.4 24.0 14.7 43.1 20.0 15.0 9.2 12.5 26.2 4.2 4.1 0.0 22.7 1.3 3.5 35.9 29.4 1.2 3.6 21.1 21.2 16.7 39.8 16.8 7.5 2.5 2.9 37.1 70.6 20.4 8.4 42.4 13.6 18.3 31.0 20.9 4.3 23.0 19.5 10.6 19.7 19.0 15.0 0.0 36.2 29.2 22.4 4.1 28.2 13.2 38.4 1.3 4.5 14.0 12.9 19.7 35.2 23.3 3.7 2.7 17.9 22.0 46.1 9.8 9.5 11.7 20.4 SF3B3 "KIAA0017, RSE1, SAP130, SF3b130" ENSG00000189091 "Splicing factor 3b subunit 3" Q15393 16 70523791-70577670 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041134, HPA042986" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No 50000 "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA041134: AB_2677317, HPA042986: AB_10960386" "unprognostic (3.39e-2)" "unprognostic (1.53e-1)" "unprognostic (7.47e-2)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (1.06e-2)" "unprognostic (7.67e-2)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (6.97e-2)" "unprognostic (2.29e-1)" "unprognostic (3.28e-2)" "unprognostic (1.60e-1)" "unprognostic (8.76e-2)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" 15.7 11.2 7.9 19.2 8.2 22.2 13.8 15.9 9.6 16.3 11.4 17.1 13.6 17.0 10.2 19.9 16.4 11.6 12.1 8.8 9.7 12.5 12.3 11.7 24.3 7.0 6.9 22.3 13.8 16.8 7.9 14.1 7.5 11.6 13.2 16.3 12.6 10.7 23.6 19.9 12.9 16.0 6.5 13.9 13.2 10.2 10.4 23.7 14.5 11.7 26.6 14.2 14.4 12.0 72.4 72.6 93.4 65.3 45.5 41.6 74.0 66.3 55.5 84.5 67.3 75.6 55.8 97.1 52.6 51.8 49.9 81.4 98.0 55.7 133.0 31.5 71.1 75.1 56.7 81.0 30.6 106.1 83.9 39.8 40.1 93.9 68.8 54.1 50.9 55.3 104.6 34.2 67.4 87.5 92.9 51.6 85.2 44.8 41.9 163.2 73.3 109.7 26.9 96.4 81.4 59.8 217.7 33.8 33.8 39.2 73.9 53.0 52.7 61.9 67.8 49.2 71.6 37.4 90.4 260.7 40.9 66.9 61.3 23.4 26.1 28.1 35.8 30.8 39.3 28.4 33.1 37.5 35.3 34.3 38.8 33.7 8.3 35.5 31.2 19.1 40.2 37.4 7.9 8.2 15.9 9.6 8.8 9.7 7.0 6.9 7.5 6.5 10.4 12.0 18.9 25.6 25.7 16.6 33.0 22.4 23.2 23.4 13.1 35.5 20.5 18.3 29.3 14.3 25.4 23.9 14.6 33.6 21.6 19.7 7.9 20.7 6.3 17.8 31.9 25.4 21.1 36.8 23.2 23.2 34.7 24.2 20.4 17.5 17.7 52.3 17.5 23.6 23.6 40.4 26.5 21.8 24.4 20.6 12.8 10.3 33.8 19.2 17.8 24.4 22.7 19.4 25.7 26.2 26.7 24.9 14.0 33.1 25.1 30.2 18.1 15.7 18.8 26.7 6.6 30.2 18.8 28.7 33.3 37.6 26.1 25.4 28.3 48.2 31.6 24.7 SFSWAP "SFRS8, SWAP" ENSG00000061936 "Splicing factor SWAP" Q12872 12 131711081-131799738 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039362, HPA040063" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA039362: AB_10794089, HPA040063: AB_10795413" "unprognostic (1.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.39e-3)" "unprognostic (2.04e-1)" "unprognostic (4.45e-2)" "unprognostic (2.39e-3)" "unprognostic (7.41e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.44e-1)" "unprognostic (1.50e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (7.50e-2)" "unprognostic (2.93e-2)" "unprognostic (3.48e-1)" "unprognostic (3.66e-2)" 26.9 18.3 18.5 10.1 20.8 28.1 26.3 18.5 24.8 27.1 13.7 25.9 10.1 24.6 4.0 23.2 24.5 4.8 20.2 18.2 19.0 24.9 19.4 20.3 11.3 20.4 19.3 29.0 21.9 7.4 21.7 8.1 19.8 21.8 4.3 9.3 20.2 6.8 29.5 32.6 24.6 5.6 16.9 28.4 20.8 16.3 21.2 12.6 24.5 6.7 7.6 22.3 24.3 25.1 26.1 23.0 16.0 17.0 12.6 10.3 35.8 19.7 13.6 22.9 15.6 22.6 12.3 31.9 18.0 14.8 11.9 23.9 22.7 18.1 13.2 9.9 36.0 29.0 12.9 27.0 13.4 37.8 27.4 11.7 20.4 20.8 24.9 18.2 14.3 24.3 40.9 12.3 10.4 32.7 31.9 57.1 41.9 14.0 38.0 36.7 16.2 25.2 13.3 18.8 25.1 28.3 18.7 15.6 25.1 12.5 22.5 29.1 18.6 19.0 24.8 14.8 22.3 35.0 41.2 31.7 18.7 25.5 25.9 2.0 4.1 1.9 3.0 2.7 3.0 2.1 2.8 2.6 2.9 3.7 3.0 3.4 5.6 5.4 3.4 7.2 2.4 1.8 18.5 20.8 18.5 24.8 18.2 19.0 20.4 19.3 19.8 16.9 21.2 25.1 46.4 73.7 44.5 48.6 37.9 38.9 41.5 19.0 42.1 49.7 25.4 25.9 19.3 21.5 38.6 14.7 66.7 30.4 52.6 22.1 0.0 23.1 21.4 27.0 48.8 39.3 21.6 38.7 55.1 26.6 31.8 39.2 37.8 39.7 38.0 47.1 21.4 16.7 22.1 42.1 43.2 24.9 14.2 27.4 21.4 12.9 30.1 30.3 23.2 36.5 35.4 33.7 50.4 58.3 85.1 28.6 24.1 29.7 43.6 44.7 20.8 11.8 30.7 62.4 46.0 52.1 38.1 39.5 42.8 39.7 46.9 43.6 45.9 48.4 22.9 48.2 SFT2D1 "C6orf83, MGC19825, pRGR1" ENSG00000198818 "SFT2 domain containing 1" Q8WV19 6 166319728-166342576 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014677 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA014677: AB_2238986" "unprognostic (8.45e-2)" "unprognostic (1.43e-3)" "unprognostic (2.29e-1)" "unprognostic (1.41e-2)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.47e-4)" "prognostic unfavorable (2.19e-5)" "unprognostic (3.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.68e-1)" "unprognostic (6.53e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (4.20e-2)" "unprognostic (5.05e-2)" "prognostic favorable (5.90e-4)" "unprognostic (2.75e-2)" 40.8 43.9 55.0 35.6 61.7 35.8 45.9 62.3 76.2 35.4 54.0 52.1 39.2 26.5 68.2 36.6 33.8 34.4 30.5 54.5 59.0 51.0 24.5 37.0 50.9 64.0 59.0 31.9 51.1 36.1 17.3 48.9 65.3 47.5 50.1 12.9 70.7 28.0 22.2 24.7 39.0 24.8 62.9 41.9 50.7 26.9 57.2 41.7 46.3 27.5 47.9 40.4 29.4 72.4 47.1 39.9 41.9 86.3 76.1 65.9 56.4 70.7 69.6 56.8 85.5 80.2 103.3 43.9 55.7 68.8 90.2 59.7 62.5 67.0 88.3 58.8 88.4 53.0 35.4 133.4 65.9 134.9 106.5 61.1 78.9 65.5 58.3 81.8 31.3 73.1 96.1 46.8 90.3 68.5 42.1 241.5 40.2 154.5 36.2 28.6 45.0 105.4 141.6 46.1 8.0 34.3 45.6 87.8 73.0 48.1 46.4 252.3 28.6 33.4 60.4 87.4 79.7 40.7 32.3 50.6 70.4 84.8 85.5 141.1 90.7 126.3 62.1 98.6 38.7 88.1 47.3 52.3 103.4 72.5 50.3 51.7 166.0 58.9 107.3 204.9 79.4 92.7 55.0 61.7 62.3 76.2 54.5 59.0 64.0 59.0 65.3 62.9 57.2 72.4 45.6 41.7 66.5 25.1 103.4 86.5 127.8 262.4 59.2 10.0 136.0 103.6 25.0 51.5 143.9 108.5 0.0 153.0 154.2 109.3 90.1 154.5 70.3 52.0 49.9 55.8 28.8 63.3 15.6 126.8 259.4 81.5 61.2 73.9 149.0 31.3 65.3 30.6 211.6 15.2 13.6 162.5 168.9 178.5 178.4 25.2 85.1 143.5 99.6 21.5 198.3 31.7 111.2 16.6 71.5 155.4 146.5 47.4 108.5 239.2 115.5 140.4 96.0 9.1 85.5 69.5 64.0 159.0 93.4 72.9 102.9 131.2 74.9 63.2 131.4 194.0 SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" 13.3 35.9 9.9 10.1 12.5 16.4 14.1 12.8 13.6 14.2 17.0 21.9 20.4 11.1 13.5 19.1 14.3 8.6 33.1 10.2 12.4 24.5 36.4 8.5 14.4 11.3 12.5 16.0 33.7 23.1 21.5 8.8 11.6 18.8 22.7 5.7 27.8 13.2 51.4 11.5 17.3 12.2 10.6 20.9 17.3 11.9 11.3 11.0 24.7 59.3 17.8 16.4 13.8 12.5 26.2 27.6 8.7 41.8 10.4 19.7 33.0 16.3 19.8 21.0 21.8 45.9 43.2 62.6 15.6 14.9 22.4 48.2 57.5 36.3 24.3 33.1 65.7 28.7 18.4 47.3 37.1 49.7 28.8 21.1 34.4 22.0 63.8 19.5 25.0 46.5 45.2 17.5 13.6 29.6 53.8 60.4 11.8 50.2 32.5 51.7 27.1 49.0 24.3 17.3 25.2 13.9 10.8 42.2 61.9 11.1 26.0 28.4 11.5 10.6 21.9 19.8 37.6 42.6 53.0 56.3 16.2 72.6 7.2 2.5 18.1 1.9 6.5 19.5 10.8 12.5 7.9 7.1 21.2 7.0 12.1 9.8 2.2 7.3 15.9 10.6 6.0 11.1 9.9 12.5 12.8 13.6 10.2 12.4 11.3 12.5 11.6 10.6 11.3 12.5 8.0 6.4 5.6 29.0 16.9 12.0 25.8 39.9 23.3 7.9 17.8 18.2 36.2 12.8 19.1 14.7 2.1 37.6 6.2 13.2 58.7 28.4 27.4 7.6 8.9 8.4 18.0 33.6 22.3 23.8 25.8 12.4 14.3 7.9 5.7 28.5 7.1 31.5 29.2 6.7 29.1 24.7 30.5 17.6 5.0 69.3 8.7 13.1 12.4 8.4 11.3 7.7 10.3 22.1 19.5 17.6 12.1 13.5 31.9 28.0 29.8 65.6 13.5 11.3 6.6 22.3 10.6 27.7 15.2 26.9 9.1 21.9 9.2 44.5 45.8 20.5 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.1;Microglial cells: 229.5;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 422.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" 15.8 19.3 19.8 10.7 27.4 24.0 14.5 21.5 20.3 16.9 33.9 10.1 13.5 11.9 19.9 15.3 16.6 15.4 13.2 17.2 23.0 20.2 27.9 21.9 14.9 29.5 24.1 18.6 13.3 52.9 6.4 24.6 28.5 19.5 11.7 20.2 18.0 16.8 9.9 25.3 16.0 15.8 23.6 11.7 14.3 11.3 23.4 12.0 24.7 10.5 14.5 20.9 13.1 41.3 30.2 14.0 4.0 9.0 14.2 18.6 18.8 19.6 19.7 13.5 12.6 11.7 30.3 22.1 11.3 25.9 12.2 18.7 9.5 20.6 14.0 19.4 10.2 32.7 17.9 9.0 16.5 7.5 7.6 12.1 23.6 18.0 21.7 8.7 19.3 7.9 62.6 32.2 14.6 12.7 3.3 4.2 9.2 13.7 13.7 5.5 18.4 8.8 19.7 31.2 6.2 4.9 14.4 14.2 7.5 11.3 21.4 2.7 27.1 14.6 17.8 14.1 14.6 11.0 9.5 6.3 18.2 12.0 12.1 3.4 9.3 28.4 4.6 4.9 10.3 7.0 6.2 6.8 5.2 6.5 8.2 5.4 16.7 10.1 4.0 3.2 15.6 6.3 19.8 27.4 21.5 20.3 17.2 23.0 29.5 24.1 28.5 23.6 23.4 41.3 17.1 44.8 40.0 106.7 19.9 54.4 28.9 15.6 23.9 20.1 15.8 8.9 26.3 10.0 30.0 29.5 4.2 10.9 15.6 6.2 15.6 17.6 17.0 20.9 10.5 19.6 14.9 32.0 153.1 21.6 7.7 19.8 30.5 32.4 20.8 12.1 17.9 16.0 29.0 5.0 117.2 11.1 4.1 46.5 17.6 30.6 16.1 34.5 12.4 229.5 12.4 17.4 10.3 313.1 422.0 10.7 6.4 10.5 13.7 32.3 18.4 9.3 25.1 36.4 0.0 20.5 27.1 12.8 2.3 18.7 83.4 4.9 20.0 11.8 12.4 25.4 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SH2B1 "FLJ30542, SH2B" ENSG00000178188 "SH2B adaptor protein 1" Q9NRF2 16 28846600-28874212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060663, HPA076175" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Centriolar satellite, Cytosol" "HPA060663: , HPA076175: AB_2686782" "unprognostic (3.60e-2)" "unprognostic (1.94e-2)" "unprognostic (8.94e-2)" "unprognostic (2.27e-1)" "unprognostic (3.27e-1)" "unprognostic (3.27e-3)" "unprognostic (6.10e-2)" "prognostic favorable (9.40e-4)" "unprognostic (3.94e-2)" "unprognostic (1.18e-1)" "prognostic favorable (4.38e-4)" "unprognostic (1.39e-2)" "prognostic favorable (2.81e-6)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.60e-4)" 36.7 57.4 53.8 32.8 54.8 38.6 39.5 58.6 75.2 58.5 42.8 59.7 46.4 54.9 20.9 39.4 54.3 30.0 52.9 53.6 47.0 62.1 44.6 35.6 39.2 49.0 47.8 69.4 53.4 55.2 70.1 20.9 48.8 57.7 28.5 29.1 49.2 36.8 58.2 40.6 57.1 24.8 38.1 63.4 51.9 48.8 51.4 36.5 71.6 50.6 25.2 47.1 44.9 58.4 29.9 43.2 32.3 41.7 33.3 28.2 26.9 30.4 17.1 23.4 25.3 29.0 49.2 27.4 41.7 24.5 20.2 46.4 21.3 33.9 13.2 35.9 27.6 24.4 111.3 45.0 25.2 24.8 22.4 39.4 27.2 32.9 13.3 40.0 27.4 27.8 39.8 39.1 31.3 40.3 37.2 36.4 41.9 15.6 17.3 62.3 19.4 46.1 27.2 22.2 36.9 49.7 14.7 42.4 22.3 19.1 33.4 26.5 38.8 26.9 22.5 23.8 23.6 74.0 40.2 30.9 41.8 43.0 27.5 3.3 1.4 0.6 2.0 1.1 1.9 1.6 1.6 1.4 1.1 1.7 1.2 1.1 2.1 0.6 1.1 1.9 1.8 0.9 53.8 54.8 58.6 75.2 53.6 47.0 49.0 47.8 48.8 38.1 51.4 58.4 14.1 6.4 13.7 37.5 13.9 10.8 15.9 15.4 22.8 26.7 17.4 13.8 18.4 17.2 15.7 22.0 33.3 16.6 12.8 31.1 15.6 9.5 2.2 11.0 11.0 12.7 27.6 7.8 25.6 12.9 8.2 15.0 19.4 11.4 6.3 20.1 13.9 8.9 12.2 28.6 26.8 24.7 14.2 8.7 7.2 5.4 22.1 10.8 3.6 13.1 10.7 18.1 22.6 21.6 19.0 12.8 24.9 23.7 10.5 10.4 26.3 10.2 12.5 28.9 26.3 12.9 15.7 9.9 12.8 17.4 11.1 13.7 15.3 20.4 28.4 12.3 SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 117.9;Pancreatic endocrine cells: 81.3;Urothelial cells: 87.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 43.2;HaCaT: 34.2;HBEC3-KT: 67.4" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: AB_10670024, HPA064382: AB_2685251" "unprognostic (3.32e-2)" "unprognostic (5.48e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-3)" "unprognostic (3.63e-1)" "unprognostic (8.41e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.21e-4)" "prognostic favorable (1.42e-4)" "unprognostic (7.31e-2)" "unprognostic (1.74e-1)" "unprognostic (1.32e-3)" "unprognostic (1.81e-3)" 0.9 0.4 0.2 4.6 0.2 3.4 7.5 0.1 0.6 8.0 0.5 12.8 14.3 1.2 1.0 32.5 4.3 3.5 0.6 0.1 0.1 19.6 2.6 10.8 5.2 0.4 0.2 0.8 19.7 5.9 2.8 5.9 0.2 18.1 5.4 0.9 18.7 4.1 1.5 27.6 14.4 0.3 0.2 5.7 14.2 4.4 0.3 3.3 13.0 0.0 4.1 9.1 17.0 0.5 43.2 6.2 0.1 0.2 0.0 0.0 22.6 0.3 0.0 0.0 0.0 20.3 30.8 6.6 19.6 0.0 0.0 34.2 2.3 67.4 0.0 3.6 6.6 0.3 6.9 2.6 0.1 0.6 8.6 0.0 30.3 0.0 5.9 0.8 0.0 14.8 7.3 14.3 0.0 15.3 3.2 0.2 1.6 21.5 12.0 1.2 0.1 24.8 11.5 31.4 0.0 0.2 2.3 31.7 0.1 1.0 22.0 0.4 0.7 0.7 2.2 0.5 0.4 14.1 15.8 9.2 0.2 4.8 0.3 0.1 0.0 0.0 2.6 0.1 4.2 3.6 5.9 5.2 0.1 5.6 7.7 4.2 0.1 1.8 0.1 0.4 3.2 0.9 0.2 0.2 0.1 0.6 0.1 0.1 0.4 0.2 0.2 0.2 0.3 0.5 0.7 19.2 14.2 0.3 25.8 30.7 117.9 51.4 25.0 4.1 13.6 11.4 1.9 40.0 43.9 40.5 10.4 23.8 7.7 46.6 1.9 54.1 1.6 15.4 2.9 2.8 12.1 7.8 0.1 37.1 52.8 2.6 50.0 24.9 5.7 0.3 1.8 2.9 3.6 0.0 0.2 37.9 28.5 0.6 10.3 0.8 0.6 2.2 3.6 0.0 4.2 0.8 14.4 0.0 0.1 81.3 69.7 0.0 8.0 58.6 53.9 13.1 27.0 4.6 0.0 2.2 3.5 8.7 11.4 17.6 39.9 10.8 18.0 1.1 32.0 87.9 SH2D7 LOC646892 ENSG00000183476 "SH2 domain containing 7" A6NKC9 15 78077808-78104909 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "intestine: 2.1;testis: 3.1" "Group enriched" "Detected in some" 4 "Early spermatids: 21.1;Late spermatids: 35.1" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051320, HPA058382, HPA076728" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA051320: AB_2681439, HPA058382: , HPA076728: " "unprognostic (1.22e-2)" "unprognostic (4.31e-2)" "unprognostic (2.24e-1)" "unprognostic (1.24e-2)" "unprognostic (2.53e-1)" "unprognostic (1.42e-1)" "unprognostic (2.99e-2)" "unprognostic (7.26e-2)" "unprognostic (1.38e-1)" "unprognostic (8.63e-3)" "unprognostic (4.73e-2)" "unprognostic (2.92e-1)" "unprognostic (2.32e-3)" "unprognostic (5.15e-3)" "unprognostic (1.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.1 1.7 0.1 0.2 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.7 1.3 0.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 21.1 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.4 0.2 0.0 0.0 3.0 0.0 0.0 0.4 0.0 SH3BP5L KIAA1720 ENSG00000175137 "SH3 binding domain protein 5 like" Q7L8J4 1 248810446-248825915 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.7;eosinophil: 4.1;neutrophil: 4.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038067, HPA038068" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA038067: AB_2675814, HPA038068: AB_10670651" "unprognostic (2.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (4.41e-1)" "unprognostic (2.78e-1)" "unprognostic (2.27e-3)" "unprognostic (1.99e-3)" "unprognostic (5.84e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (1.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-2)" "unprognostic (4.66e-2)" 9.6 10.5 18.0 10.1 18.7 9.0 7.7 17.3 21.0 8.8 13.9 12.2 13.5 10.5 7.8 15.8 10.0 8.0 14.1 19.4 15.8 9.5 10.5 9.2 11.3 17.0 16.7 8.6 10.0 12.0 5.9 11.4 16.9 9.1 7.3 5.3 11.9 11.6 30.6 18.4 12.4 9.9 15.8 12.3 9.9 9.5 17.1 13.8 8.1 17.8 10.2 9.0 9.1 18.3 23.2 14.7 18.5 21.2 25.7 17.1 24.6 51.1 17.4 29.2 21.8 14.3 20.0 11.6 29.7 44.1 7.3 24.6 17.9 22.1 15.0 25.4 6.3 18.6 16.4 11.9 15.8 20.4 21.9 14.4 23.4 33.0 12.9 20.7 19.6 21.4 33.0 12.0 20.2 7.9 19.7 16.5 32.4 25.5 36.9 21.9 13.0 23.5 20.5 10.6 21.1 29.2 15.6 19.3 17.9 14.0 21.0 42.4 27.5 36.9 15.7 14.7 80.2 30.5 34.3 10.5 26.8 23.5 15.4 7.7 1.2 4.1 0.7 0.8 0.7 0.6 1.0 0.6 1.1 0.6 0.3 0.3 4.6 0.3 0.3 0.4 0.2 0.8 18.0 18.7 17.3 21.0 19.4 15.8 17.0 16.7 16.9 15.8 17.1 18.3 5.2 0.0 2.0 5.9 4.3 4.6 2.1 2.9 4.0 8.3 6.1 5.0 9.4 1.5 2.3 11.0 0.0 9.6 4.7 15.1 1.9 8.8 1.3 10.5 5.4 6.0 7.7 6.9 6.5 6.0 5.2 4.9 7.7 6.1 0.0 9.0 6.1 10.0 6.0 8.4 5.7 8.4 2.0 5.3 4.5 1.0 4.4 5.6 3.6 3.7 7.1 4.7 6.2 6.0 6.4 10.6 8.1 5.7 5.4 3.0 13.8 9.2 5.1 3.5 0.0 3.7 5.8 8.8 7.0 7.0 4.7 11.4 6.3 5.4 7.3 3.3 SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.8;retina: 75.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 89.4;Excitatory neurons: 390.8;Inhibitory neurons: 140.9" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 9.3;HeLa: 21.1;JURKAT: 18.7;RT4: 41.8;SCLC-21H: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 6: Brain - Smell perception" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: AB_628099, HPA026685: AB_1856817, HPA063573: AB_2685045" "unprognostic (4.78e-2)" "unprognostic (3.24e-2)" "unprognostic (1.68e-2)" "unprognostic (5.05e-5)" "unprognostic (4.23e-2)" "unprognostic (3.40e-1)" "unprognostic (1.21e-1)" "unprognostic (5.90e-2)" "unprognostic (3.90e-1)" "unprognostic (5.07e-3)" "unprognostic (8.76e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.68e-12)" "unprognostic (2.65e-2)" "unprognostic (8.29e-2)" "unprognostic (2.25e-2)" "unprognostic (8.44e-2)" 0.3 0.2 63.0 0.1 69.0 0.0 0.1 92.3 123.8 2.3 1.9 0.5 0.2 2.2 1.2 0.5 2.0 0.0 4.3 77.7 26.6 16.8 0.2 1.1 0.0 27.9 28.5 1.8 3.0 0.3 26.2 0.0 25.9 1.8 0.6 75.0 0.1 0.1 0.1 0.1 0.5 1.7 29.3 0.1 8.7 6.5 41.1 0.7 1.5 0.0 0.0 4.3 0.4 55.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.0 7.5 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 9.3 0.0 21.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.1 0.2 2.5 0.0 2.4 0.0 0.0 0.0 0.0 41.8 26.5 0.0 0.3 0.0 0.8 0.8 0.0 0.0 0.0 0.0 2.2 0.0 1.5 0.0 0.4 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.0 69.0 92.3 123.8 77.7 26.6 27.9 28.5 25.9 29.3 41.1 55.5 0.0 0.0 0.0 16.3 0.0 0.1 0.4 0.0 0.0 89.4 0.1 0.0 1.8 0.0 0.0 7.3 22.9 0.0 0.0 0.1 11.7 0.0 16.7 0.2 0.1 0.3 5.3 0.0 390.8 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.1 13.5 140.9 0.7 0.0 0.0 0.3 47.4 1.2 0.1 0.0 13.1 0.1 9.0 0.0 41.7 10.2 0.2 0.1 0.4 0.0 2.2 0.0 22.2 0.0 28.0 0.0 0.0 0.1 2.4 6.1 0.0 0.0 0.1 0.0 1.2 0.7 0.4 SH3TC1 FLJ20356 ENSG00000125089 "SH3 domain and tetratricopeptide repeats 1" Q8TE82 4 8182072-8241803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 32.6;Kupffer cells: 33.7;Macrophages: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.7" "Group enriched" "Detected in many" 5 "B-cells: 6.8;dendritic cells: 17.7;monocytes: 12.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.8;MOLT-4: 41.8;SK-MEL-30: 26.8;U-2197: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038132, HPA056807" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA038132: AB_10673041, HPA056807: AB_2683239" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "unprognostic (1.61e-3)" "unprognostic (5.46e-2)" "unprognostic (2.26e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (8.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.59e-2)" "unprognostic (4.24e-2)" "unprognostic (2.46e-1)" "unprognostic (3.77e-3)" "unprognostic (1.15e-2)" "unprognostic (4.29e-2)" 8.4 3.5 4.0 8.7 4.3 4.6 5.6 4.1 5.6 2.9 5.2 2.8 0.9 2.1 0.7 8.4 3.0 5.4 3.6 3.6 7.3 19.2 9.6 9.0 9.1 10.5 6.0 1.2 6.3 0.7 2.5 3.0 8.5 4.7 1.0 1.3 4.6 2.7 1.5 2.7 4.9 2.0 9.2 14.1 6.0 0.6 8.4 28.0 4.6 0.7 4.5 4.4 5.8 11.8 3.9 6.1 0.1 0.0 0.0 0.5 4.1 0.4 0.2 0.5 0.8 3.2 2.2 5.2 5.2 0.0 0.8 2.0 0.0 12.4 0.0 14.2 0.2 0.0 6.1 5.7 4.3 0.1 0.8 0.2 15.3 0.3 9.9 0.5 25.8 3.2 0.8 7.3 0.4 4.1 41.8 3.4 0.0 2.3 5.1 3.1 0.7 1.6 0.4 1.0 0.1 3.1 1.7 0.4 26.8 1.0 0.0 1.0 14.2 0.0 3.0 19.0 0.2 0.0 1.0 4.7 0.2 1.9 4.1 0.0 9.9 1.3 0.7 8.8 0.9 4.9 1.7 1.1 7.7 6.8 0.9 0.7 0.3 0.3 12.3 17.7 2.5 4.3 4.0 4.3 4.1 5.6 3.6 7.3 10.5 6.0 8.5 9.2 8.4 11.8 12.6 0.0 5.8 1.3 18.1 0.8 10.5 6.9 0.6 1.0 0.8 1.4 3.3 4.3 4.1 25.8 0.0 2.1 18.2 2.5 7.9 3.6 0.5 0.9 0.3 12.6 1.2 3.2 0.2 5.6 3.4 1.6 32.6 2.2 17.2 0.3 27.5 8.6 22.7 23.5 0.1 2.5 14.2 33.7 16.7 1.5 0.6 35.7 0.0 17.8 15.6 13.3 7.2 0.5 0.1 9.3 4.5 0.7 17.1 8.3 0.1 17.2 2.0 0.9 0.0 0.6 1.2 0.0 0.3 2.5 0.6 3.0 11.7 2.5 1.8 15.3 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHARPIN "DKFZP434N1923, SIPL1" ENSG00000179526 "SHANK associated RH domain interactor" Q9H0F6 8 144098633-144108124 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 391.4;Late spermatids: 1255.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024825, HPA044453" Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA024825: , HPA044453: AB_10962490" "unprognostic (4.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.35e-2)" "unprognostic (7.88e-2)" "unprognostic (3.32e-2)" "unprognostic (9.54e-2)" "unprognostic (1.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.13e-3)" "unprognostic (5.44e-2)" "unprognostic (7.91e-2)" "unprognostic (1.84e-3)" "unprognostic (2.87e-2)" "unprognostic (1.55e-1)" "unprognostic (2.24e-1)" "unprognostic (1.00e-1)" 29.9 39.2 38.5 16.5 39.9 32.6 27.2 39.1 52.2 29.9 35.7 37.7 20.7 29.4 11.2 29.9 28.8 19.4 44.4 36.0 39.2 36.7 39.1 27.1 21.8 41.7 39.7 27.4 35.1 28.7 26.7 17.2 39.9 33.8 12.7 8.9 33.8 22.2 49.4 27.1 26.3 17.3 37.7 33.4 34.2 94.7 39.8 19.6 29.1 39.7 13.9 31.2 26.4 38.7 26.9 43.5 20.4 17.9 34.2 35.1 22.5 23.5 29.5 34.0 32.9 24.9 42.0 12.0 38.5 30.6 17.1 28.4 10.8 42.2 8.2 33.0 23.3 31.4 40.1 29.9 61.6 11.6 23.1 40.4 59.4 28.3 30.8 37.6 36.8 36.6 18.2 27.3 30.2 43.8 35.2 26.6 9.3 53.6 124.2 23.6 16.7 39.4 35.2 28.3 20.3 30.7 45.0 62.1 41.5 14.3 69.4 35.8 34.0 26.5 38.9 32.5 32.4 30.0 25.4 16.3 38.3 25.9 23.5 22.6 33.5 53.5 29.9 41.2 32.4 23.3 28.5 38.3 30.0 21.8 23.5 24.7 17.5 33.9 34.8 42.7 34.1 22.4 38.5 39.9 39.1 52.2 36.0 39.2 41.7 39.7 39.9 37.7 39.8 38.7 56.3 9.6 18.1 10.4 39.4 24.0 32.9 37.0 26.2 27.1 43.5 44.4 20.9 31.5 26.1 35.0 4.2 56.7 44.4 87.2 119.3 53.8 391.4 28.3 26.8 38.9 35.4 88.0 8.0 49.5 52.6 35.9 52.0 24.4 13.3 35.1 36.4 37.2 59.0 48.8 9.5 45.6 44.7 42.1 32.9 1255.3 49.0 33.0 46.2 15.0 57.7 45.4 59.8 9.0 14.3 95.2 81.3 43.6 31.2 36.1 83.1 86.4 20.6 28.9 52.6 26.8 44.2 181.7 67.9 33.5 32.4 43.1 38.8 37.4 59.0 33.9 SHB ENSG00000107338 "SH2 domain containing adaptor protein B" Q15464 9 37915898-38069227 "Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "OE19: 35.3" "Low region specificity" "Detected in all" "CAB010161, HPA049911, HPA052108" Uncertain Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Nucleoplasm, Cytoplasmic bodies" "CAB010161: AB_2187742, HPA049911: AB_2680949, HPA052108: AB_2681730" "unprognostic (4.57e-2)" "unprognostic (1.13e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.38e-1)" "unprognostic (1.38e-1)" "unprognostic (1.79e-1)" "unprognostic (5.96e-3)" "unprognostic (2.48e-2)" "unprognostic (3.31e-3)" "unprognostic (7.68e-3)" "unprognostic (1.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.10e-1)" 12.8 7.6 6.4 1.9 9.6 3.1 9.8 6.1 9.2 8.8 8.2 11.2 3.6 6.6 1.2 26.2 7.2 4.9 24.9 6.7 6.3 23.1 35.2 13.9 1.3 8.5 9.7 4.7 20.0 4.1 15.0 2.5 7.8 16.1 2.6 0.9 23.2 4.6 6.8 17.3 7.1 3.2 5.6 6.6 10.6 4.1 9.4 1.7 8.3 1.3 2.5 13.6 16.1 12.8 8.3 14.6 1.4 0.2 1.5 3.8 2.5 9.8 11.5 6.9 5.0 4.5 5.8 0.0 10.9 8.5 16.9 8.8 5.8 14.2 4.8 6.7 11.0 0.0 5.3 10.7 10.8 0.4 0.4 3.4 4.9 11.2 7.8 16.1 6.5 1.4 3.6 2.4 7.7 6.2 0.9 0.3 3.7 35.3 13.0 0.4 4.3 0.5 13.1 3.8 15.8 12.1 1.3 10.9 2.2 11.9 6.5 0.4 9.2 3.3 11.0 1.6 16.2 0.7 0.2 0.1 18.3 0.8 2.9 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 9.6 6.1 9.2 6.7 6.3 8.5 9.7 7.8 5.6 9.4 12.8 21.5 6.4 5.6 9.8 0.6 20.4 96.9 9.9 33.0 0.6 12.7 6.0 9.6 35.8 9.0 22.0 8.4 10.2 1.1 17.3 15.6 18.0 1.9 8.3 2.5 19.0 7.8 5.2 6.4 20.3 1.5 5.5 14.8 18.3 0.0 0.9 10.4 21.6 6.1 0.0 5.4 12.1 2.0 2.6 19.4 3.8 0.6 5.8 7.2 8.4 0.4 2.9 0.0 5.0 43.7 22.2 6.8 0.4 1.9 31.1 7.5 24.9 5.1 1.4 0.0 5.7 3.9 1.2 9.4 19.3 34.0 4.0 1.2 9.3 11.1 45.9 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.4;skeletal muscle: 14.2;thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.1;Basal prostatic cells: 14.6;Breast glandular cells: 24.1;Oligodendrocytes: 10.9;Urothelial cells: 19.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 26.7;JURKAT: 20.8;LHCN-M2: 18.7;NTERA-2: 15.5;RH-30: 46.3;U-2197: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" 0.5 0.0 1.1 0.2 2.3 0.1 12.4 1.5 2.0 1.7 0.9 0.1 0.7 0.1 7.8 0.2 0.2 0.5 0.2 2.0 1.5 4.7 0.0 4.3 0.5 1.9 1.5 0.3 0.3 0.1 1.6 0.0 1.6 0.5 0.1 0.0 2.7 0.3 14.2 1.1 0.7 0.1 2.2 0.2 2.1 1.2 1.6 2.5 21.0 1.2 0.7 0.7 0.0 5.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.4 4.2 1.4 0.0 0.0 1.7 26.7 1.0 20.8 0.0 0.0 18.7 1.2 2.3 0.5 15.5 8.4 8.2 0.0 46.3 0.3 1.7 6.5 0.4 0.0 0.4 0.0 5.4 2.6 0.7 0.2 1.6 0.1 0.7 30.4 7.0 0.0 0.0 0.0 0.0 0.0 4.1 0.8 0.1 0.5 0.1 0.2 0.2 0.1 0.4 0.1 0.0 0.2 1.0 1.6 0.4 0.2 0.3 0.1 0.2 0.1 1.1 2.3 1.5 2.0 2.0 1.5 1.9 1.5 1.6 2.2 1.6 5.4 4.7 0.0 13.1 0.0 0.4 5.4 14.6 2.3 0.6 0.0 24.1 6.2 0.5 0.0 1.5 3.7 0.0 0.3 0.3 0.1 0.0 6.0 2.6 1.0 0.5 5.1 0.0 0.0 0.0 0.2 0.3 2.8 3.1 2.5 0.0 2.4 1.1 0.0 0.8 0.0 1.0 0.1 8.2 0.3 2.3 1.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.5 10.9 1.2 0.0 0.4 0.2 3.9 0.0 0.3 1.1 0.0 0.0 7.6 1.6 0.7 5.1 0.4 1.7 0.1 1.1 0.7 0.0 19.6 SHLD1 "C20orf196, FLJ25067, RINN3" ENSG00000171984 "Shieldin complex subunit 1" Q8IYI0 20 5750393-5864395 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 12.9;dendritic cells: 13.1;Distal tubular cells: 19.6;Exocrine glandular cells: 14.2;Hofbauer cells: 17.0;Pancreatic endocrine cells: 11.7;Proximal tubular cells: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 55.7;U-698: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040749 Approved Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Golgi apparatus, Vesicles" "HPA040749: AB_10673093" "unprognostic (2.03e-1)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "unprognostic (4.20e-3)" "unprognostic (6.15e-2)" "unprognostic (1.66e-1)" "unprognostic (1.72e-3)" "unprognostic (6.66e-2)" "unprognostic (9.04e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-2)" "unprognostic (7.59e-3)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "prognostic favorable (4.05e-5)" 4.0 9.7 5.0 6.2 5.8 16.7 5.3 7.2 6.1 5.1 4.6 5.1 9.1 3.8 5.3 5.4 3.9 4.4 8.6 4.9 5.8 6.7 3.0 4.8 14.3 5.6 5.3 5.1 5.2 2.4 6.0 3.0 6.3 6.3 4.9 4.0 8.4 3.7 12.0 4.1 7.1 2.6 4.6 9.9 4.7 3.1 5.4 13.3 6.6 7.7 12.1 4.5 4.7 6.4 9.2 9.6 4.6 2.3 2.8 2.8 2.3 2.5 4.5 3.1 4.3 4.5 9.4 33.3 6.3 2.5 2.5 4.1 2.8 6.1 3.6 10.3 3.4 12.9 1.4 18.2 6.2 16.2 5.7 3.3 7.2 4.7 3.1 3.0 6.4 8.7 17.8 13.9 5.9 3.5 20.4 55.7 6.3 10.3 5.2 16.5 7.1 15.1 5.0 4.5 8.2 7.4 4.6 4.7 10.0 2.6 3.9 13.2 4.3 3.6 5.4 3.5 5.4 8.7 16.6 45.8 1.8 13.9 6.4 21.7 12.4 22.5 21.3 14.8 16.4 27.7 25.2 21.5 12.7 33.1 22.9 17.2 4.9 23.5 16.9 15.1 31.5 13.0 5.0 5.8 7.2 6.1 4.9 5.8 5.6 5.3 6.3 4.6 5.4 6.4 9.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 6.4 8.6 0.0 0.0 0.0 12.9 0.0 7.5 13.1 0.0 19.6 7.9 0.0 6.4 4.4 2.8 0.0 0.0 0.0 14.2 7.5 1.7 0.0 5.2 0.0 7.3 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.3 0.0 0.0 11.7 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 5.9 6.4 5.0 0.0 0.0 SHPRH "bA545I5.2, FLJ90837, KIAA2023" ENSG00000146414 "SNF2 histone linker PHD RING helicase" Q149N8 6 145864245-145964423 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Helicase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 210.6;Oligodendrocytes: 164.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034854, HPA044852" Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane" Cytosol "HPA034854: AB_10964488, HPA044852: " "unprognostic (3.10e-2)" "unprognostic (4.46e-2)" "unprognostic (5.61e-3)" "unprognostic (1.53e-2)" "unprognostic (7.40e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (5.03e-1)" "unprognostic (7.90e-2)" "unprognostic (6.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.01e-1)" 4.9 4.2 3.1 4.7 3.7 4.2 7.2 18.4 5.1 5.4 3.2 4.3 4.2 7.7 6.0 4.3 5.2 4.6 3.5 3.0 2.5 5.5 4.6 4.2 6.9 2.8 2.6 12.2 3.9 6.7 2.0 4.5 4.5 5.5 5.0 16.3 5.8 5.1 4.2 9.7 4.5 5.7 2.5 6.4 5.4 7.6 2.9 7.2 8.4 5.2 5.8 4.3 3.3 5.5 4.2 3.2 15.3 9.1 7.0 7.3 7.2 4.9 3.9 5.9 7.6 7.0 2.9 14.5 5.9 3.7 4.6 7.0 9.5 6.9 7.7 6.5 10.9 14.6 7.6 6.1 5.2 31.2 8.6 5.2 7.8 5.6 8.0 5.8 6.4 10.0 20.3 7.9 5.1 3.7 19.8 11.6 10.3 6.9 5.4 14.1 23.6 5.0 8.0 4.1 12.6 8.8 8.7 7.9 5.4 10.5 4.2 14.6 7.2 3.7 7.0 7.4 5.8 6.4 9.4 17.1 3.9 13.0 6.0 0.7 0.9 1.9 1.7 0.9 1.5 1.5 1.4 1.1 1.1 2.5 1.5 1.3 0.0 1.5 1.0 2.0 1.4 0.5 3.1 3.7 18.4 5.1 3.0 2.5 2.8 2.6 4.5 2.5 2.9 5.5 31.4 28.9 23.4 106.7 31.0 21.2 17.9 14.5 19.4 117.2 21.5 20.3 17.2 20.0 20.7 22.0 210.6 16.1 34.6 9.1 7.9 18.6 20.4 20.9 52.8 26.0 19.2 15.3 131.0 12.9 7.0 25.9 23.9 18.1 13.3 145.7 15.7 20.5 12.0 94.2 140.3 14.7 6.1 21.4 9.8 8.0 50.7 19.8 14.2 93.7 30.6 40.7 36.0 143.7 164.6 15.9 8.8 34.3 23.5 18.8 17.2 7.5 14.9 158.5 72.3 47.1 39.1 83.2 65.0 16.5 19.7 6.6 26.4 61.5 18.0 12.5 SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Cone photoreceptor cells: 47.9;Microglial cells: 24.4;Peritubular cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 19.2;SK-MEL-30: 18.2;SuSa: 18.6;WM-115: 23.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051646 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: AB_2681562" "unprognostic (8.65e-3)" "unprognostic (1.36e-3)" "unprognostic (4.68e-2)" "unprognostic (4.06e-2)" "unprognostic (6.99e-3)" "unprognostic (8.05e-2)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (9.73e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (1.93e-1)" "unprognostic (7.67e-3)" 0.7 1.8 4.3 0.4 6.0 0.0 1.0 3.6 10.1 2.4 5.4 1.5 0.7 1.5 2.7 5.0 1.6 3.1 0.7 5.9 4.0 3.7 4.0 4.1 0.3 4.8 5.0 6.9 3.7 2.4 4.4 7.6 4.3 5.3 1.3 20.8 3.2 2.6 0.1 4.1 0.5 0.8 4.3 0.7 1.5 3.4 4.7 3.6 1.4 0.1 1.3 2.4 3.1 5.2 6.2 0.7 11.0 1.5 0.6 1.7 6.2 0.6 2.0 2.4 3.8 7.5 0.1 0.0 2.0 1.6 0.4 4.8 5.7 15.9 2.8 0.0 4.3 0.0 0.0 1.2 3.5 0.0 7.4 0.3 10.9 18.0 0.7 3.9 13.7 0.0 0.0 0.0 3.9 6.5 0.0 0.1 9.7 0.0 0.0 0.0 12.1 0.0 10.2 19.2 1.6 0.9 0.5 0.1 18.2 18.6 6.5 0.4 6.4 17.3 2.2 0.1 0.6 0.0 0.0 0.0 11.4 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 6.0 3.6 10.1 5.9 4.0 4.8 5.0 4.3 4.3 4.7 5.2 1.1 0.0 1.5 26.4 0.0 1.9 3.3 2.8 10.8 9.5 3.4 1.7 4.1 4.3 3.1 3.7 47.9 8.9 0.0 2.0 3.9 3.0 0.5 4.8 2.5 7.2 1.2 2.7 9.5 0.0 1.3 1.5 3.1 5.9 0.0 5.4 10.0 5.7 0.7 1.7 9.5 0.3 4.1 0.8 0.0 1.0 3.7 0.2 0.0 24.4 0.0 2.4 0.0 9.5 4.6 1.6 0.1 83.1 0.0 5.4 0.1 1.0 2.8 18.0 0.0 0.6 1.8 0.1 1.1 10.8 2.0 2.1 0.5 5.5 0.9 5.3 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 128.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "classical monocyte: 19.7;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037942, HPA037943" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA037942: AB_2675748, HPA037943: AB_10671637" "unprognostic (1.00e-1)" "unprognostic (2.50e-2)" "unprognostic (6.77e-3)" "unprognostic (2.81e-1)" "unprognostic (7.85e-2)" "unprognostic (1.61e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.56e-1)" "unprognostic (1.35e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.08e-6)" 1.9 4.0 63.2 4.5 94.5 0.7 4.9 42.7 54.1 2.9 10.0 4.3 4.1 2.4 4.6 3.1 2.9 3.8 1.6 46.9 73.9 4.7 7.6 6.2 2.9 77.5 70.1 3.9 12.2 8.0 6.2 3.1 69.5 4.2 5.2 10.6 6.7 1.4 0.3 5.6 4.8 2.0 48.6 4.5 5.7 6.4 79.5 2.7 7.5 0.8 2.3 2.1 2.1 128.1 24.2 13.4 1.3 2.8 0.0 0.0 12.8 2.0 5.3 4.0 7.6 15.1 15.5 0.0 4.0 7.4 11.8 12.2 10.6 8.9 4.1 0.0 11.0 0.0 14.5 8.9 1.7 4.3 3.7 0.5 7.5 4.0 7.5 10.3 9.7 6.4 6.7 0.1 2.8 9.6 0.0 0.1 5.0 4.8 8.9 0.0 17.5 5.4 10.3 3.3 14.5 5.7 16.0 23.3 13.8 15.7 18.4 3.8 17.0 1.4 9.4 0.1 11.7 2.4 0.1 0.0 7.1 0.0 7.2 0.0 19.7 0.2 0.0 12.9 0.0 0.0 0.1 0.0 19.3 0.0 0.1 0.0 0.4 0.0 6.6 12.9 0.4 5.6 63.2 94.5 42.7 54.1 46.9 73.9 77.5 70.1 69.5 48.6 79.5 128.1 1.4 76.9 35.7 0.0 2.0 0.0 18.9 0.0 15.4 92.3 31.8 15.9 4.9 35.8 23.5 23.9 62.6 42.1 24.7 10.6 21.5 46.4 7.5 43.4 10.6 5.1 17.0 1.7 0.0 53.2 30.9 11.2 36.7 81.1 2.5 23.6 1.8 50.5 37.3 48.8 0.0 15.5 0.0 83.6 0.0 11.7 11.1 77.2 0.0 0.0 90.3 13.8 1.0 0.0 0.0 46.2 42.5 5.3 0.8 25.2 21.2 58.4 18.2 59.4 13.1 18.2 5.0 22.0 39.6 20.5 0.0 20.0 3.1 28.4 15.7 15.4 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIPA1 SPA1 ENSG00000213445 "Signal-induced proliferation-associated 1" Q96FS4 11 65638101-65650918 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.6" "Cell type enhanced" "Detected in many" "dendritic cells: 82.5;NK-cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020833, HPA039867" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB020833: , HPA039867: AB_2676716" "unprognostic (6.10e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (1.35e-2)" "unprognostic (2.93e-1)" "unprognostic (2.32e-2)" "unprognostic (3.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-1)" 21.6 17.2 16.4 48.7 15.5 53.8 16.2 14.1 16.8 20.6 10.3 24.0 12.5 20.9 3.4 14.3 19.5 16.0 25.7 15.8 13.2 17.0 15.0 37.0 60.7 22.3 16.0 13.1 8.4 3.5 7.5 19.4 19.5 17.1 6.0 0.9 14.1 10.0 10.0 8.1 37.8 12.0 19.5 95.6 15.9 4.7 24.5 21.3 14.9 6.4 32.5 18.8 15.3 21.0 1.6 13.3 9.1 20.1 5.4 11.1 21.7 14.9 12.7 11.7 11.3 3.9 14.5 21.3 33.2 7.6 0.4 7.8 3.4 5.1 3.9 22.7 8.1 52.6 20.7 7.4 9.6 21.5 21.5 11.4 2.3 16.2 2.1 11.5 34.4 21.8 30.3 9.2 5.8 5.8 8.6 36.1 6.4 5.4 12.3 38.8 5.1 19.3 4.4 0.8 3.4 20.9 7.5 12.6 31.7 8.5 9.6 32.5 49.2 14.2 28.7 15.2 3.0 14.1 12.2 48.4 19.5 33.0 42.0 3.2 3.3 9.3 5.8 3.9 4.1 4.1 2.8 3.7 2.3 4.7 2.0 3.1 11.1 4.7 4.8 2.1 3.0 3.0 16.4 15.5 14.1 16.8 15.8 13.2 22.3 16.0 19.5 19.5 24.5 21.0 22.5 6.4 5.2 7.5 59.0 6.8 24.7 23.2 17.6 2.1 24.8 26.5 7.2 21.5 19.2 23.9 0.0 10.1 82.5 16.5 37.2 19.8 3.0 8.3 6.8 26.8 21.0 31.6 0.1 14.5 19.6 12.2 11.2 14.9 7.0 37.1 42.8 22.0 38.4 5.0 0.2 12.8 30.5 44.4 11.4 9.8 8.1 40.2 10.6 14.0 23.7 7.6 88.6 0.5 4.0 27.2 12.7 13.2 29.6 29.0 39.0 20.7 6.0 1.8 13.1 7.4 20.9 0.8 13.8 14.4 11.1 13.5 50.4 30.9 14.3 31.9 SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.2;Inhibitory neurons: 95.9;Microglial cells: 183.6;Oligodendrocyte precursor cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 69.7;NTERA-2: 53.9;WM-115: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: AB_1856886, HPA027224: AB_2672165" "unprognostic (2.34e-2)" "unprognostic (9.67e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-3)" "unprognostic (2.98e-1)" "unprognostic (5.68e-2)" "unprognostic (5.57e-3)" "unprognostic (7.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-2)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.36e-2)" "unprognostic (2.75e-1)" "unprognostic (5.84e-3)" "unprognostic (3.45e-3)" 12.1 3.3 8.5 6.4 7.2 5.4 9.2 9.6 11.7 10.0 0.5 19.4 3.9 4.4 2.8 20.3 4.5 8.5 31.3 9.6 16.0 7.7 6.4 16.2 3.0 44.0 21.7 11.9 3.6 4.4 8.1 18.3 44.6 8.1 18.9 14.7 8.7 4.7 7.1 9.0 9.2 7.4 14.4 9.6 5.7 7.2 18.7 2.4 8.0 9.5 3.3 12.5 14.9 9.0 0.0 7.5 69.7 0.2 0.6 0.0 29.3 1.2 2.5 3.1 2.2 2.9 0.1 5.9 13.3 26.4 2.9 1.7 13.8 2.3 2.9 0.0 12.8 0.0 7.0 0.0 5.9 1.0 7.2 3.8 9.1 0.6 6.2 0.0 15.7 25.4 0.0 0.1 1.6 3.5 7.4 0.7 53.9 0.2 10.2 0.0 0.0 3.4 8.1 11.5 3.5 11.9 23.8 0.8 9.5 15.8 1.4 0.6 5.6 8.1 0.0 17.8 2.9 6.5 0.0 0.0 10.0 6.2 46.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.6 0.3 0.3 0.0 0.1 8.5 7.2 9.6 11.7 9.6 16.0 44.0 21.7 44.6 14.4 18.7 9.0 53.7 6.4 1.8 22.9 0.8 8.8 9.8 8.7 15.4 23.5 10.7 8.6 62.6 12.8 10.4 3.7 52.1 4.9 4.4 29.9 0.0 7.1 11.7 19.0 21.4 22.7 7.2 0.4 80.2 0.5 7.1 15.2 5.1 47.5 1.3 16.0 1.8 3.8 10.0 5.0 95.9 29.5 14.2 16.6 7.2 9.8 0.9 19.5 14.2 183.6 6.3 12.7 1.0 104.0 21.0 1.4 39.9 1.9 0.5 13.2 9.1 0.4 7.7 35.7 0.0 21.8 23.9 6.9 24.0 45.8 7.4 14.8 2.0 11.9 23.4 23.0 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SIRT1 SIR2L1 ENSG00000096717 "Sirtuin 1" Q96EB6 10 67884656-67918390 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Early spermatids: 292.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003855, HPA006295, HPA052351" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli fibrillar center, Mitochondria, Cytosol" "CAB003855: AB_365497, HPA006295: AB_1079975, HPA052351: AB_2681796" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (9.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" "unprognostic (2.48e-1)" "unprognostic (4.95e-2)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (2.18e-2)" "unprognostic (2.83e-2)" "unprognostic (9.67e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" 16.4 30.2 8.9 11.0 10.4 19.8 17.5 15.6 11.9 17.1 7.8 12.5 9.2 18.5 11.9 10.9 11.9 14.0 10.6 8.5 9.9 13.4 17.3 12.6 17.7 9.3 9.2 25.1 12.1 14.0 6.9 12.7 10.0 14.0 12.0 13.5 9.9 11.2 14.6 9.6 9.7 13.7 8.8 14.3 10.3 26.8 9.4 19.2 14.7 18.5 15.1 15.5 9.5 12.9 15.1 16.8 26.2 29.4 24.4 18.7 16.3 20.4 21.0 27.4 24.3 18.7 12.6 31.4 10.8 13.7 17.1 11.7 32.8 6.9 29.3 16.9 19.0 16.7 12.1 14.7 22.3 18.1 12.3 17.3 16.2 16.6 28.3 29.4 11.2 17.6 21.6 16.7 20.3 12.1 17.0 25.0 32.5 9.6 26.6 30.3 20.6 12.4 13.1 9.1 16.8 23.0 37.4 24.4 26.8 22.5 17.7 16.6 9.4 21.2 19.8 19.0 20.1 13.9 17.7 61.8 10.9 27.2 8.9 1.3 0.8 1.1 1.1 1.0 1.6 1.8 1.2 1.5 1.3 1.0 2.2 1.3 1.0 1.2 1.3 1.2 1.0 0.6 8.9 10.4 15.6 11.9 8.5 9.9 9.3 9.2 10.0 8.8 9.4 12.9 35.7 19.2 7.4 17.0 27.6 39.1 20.9 7.2 22.8 12.5 48.3 33.4 34.8 11.5 8.7 5.5 27.1 7.1 42.5 31.2 5.9 4.3 292.2 38.4 26.2 20.6 42.9 10.3 16.0 5.6 5.4 28.0 23.4 57.1 12.0 14.8 15.4 15.8 9.1 11.8 18.4 21.0 10.2 23.4 28.7 45.6 17.7 34.1 16.0 30.9 14.8 7.1 9.2 18.6 30.7 6.2 20.6 19.5 15.8 26.0 11.2 8.4 4.1 14.0 0.0 43.4 28.8 24.2 16.3 21.1 47.5 12.4 29.1 8.9 18.7 17.2 SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 302.1;tongue: 218.2" "Cell type enhanced" "Detected in all" "Early spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" 43.2 44.0 101.6 11.5 137.5 17.4 39.7 141.1 123.0 41.5 79.4 49.2 12.6 37.2 10.4 42.5 37.2 15.0 76.9 100.7 111.2 35.9 51.5 38.2 13.7 151.0 129.6 49.0 33.4 18.2 31.2 10.5 144.7 32.7 10.2 11.9 41.5 14.9 302.1 48.8 32.4 18.3 121.3 40.1 41.4 43.5 127.6 13.1 34.5 218.2 13.0 41.3 37.8 173.5 16.1 9.8 8.4 20.6 46.7 31.8 5.8 11.3 20.2 17.8 22.7 17.1 10.2 5.4 23.7 21.3 13.2 8.3 14.6 25.1 10.9 25.2 15.6 10.1 10.9 10.9 33.0 7.0 22.4 33.5 29.7 14.4 16.9 21.4 31.9 17.7 10.1 42.0 28.2 8.9 15.4 6.2 1.2 27.6 13.6 19.9 22.8 15.3 14.8 14.9 20.7 9.0 12.9 17.8 13.0 7.0 8.0 19.2 28.9 24.0 5.1 37.2 17.0 16.9 8.8 12.6 18.1 19.0 22.0 48.9 54.7 59.8 44.9 69.1 28.5 24.9 21.9 31.0 42.9 28.9 14.3 23.6 42.7 36.5 56.7 44.0 33.1 51.9 101.6 137.5 141.1 123.0 100.7 111.2 151.0 129.6 144.7 121.3 127.6 173.5 39.5 16.0 19.4 26.1 21.0 51.6 30.3 35.1 35.3 29.7 28.8 29.7 42.1 14.3 27.2 12.9 35.5 36.5 90.8 28.4 37.2 29.0 173.0 24.7 15.4 31.1 17.5 27.1 31.2 17.6 15.2 30.3 44.9 26.5 25.4 29.5 28.5 19.7 66.3 30.3 27.2 24.1 97.6 38.3 51.7 74.8 31.1 37.1 46.2 11.2 20.0 22.6 85.5 76.4 110.8 26.5 23.9 41.0 39.7 14.9 54.0 38.8 30.1 28.2 19.7 113.5 27.9 15.3 7.2 30.1 60.1 42.3 45.8 31.3 18.2 21.5 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SKAP1 "SCAP1, SKAP55" ENSG00000141293 "Src kinase associated phosphoprotein 1" Q86WV1 17 48133442-48430275 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "dendritic cells: 107.1;granulocytes: 120.1;Late spermatids: 156.1;NK-cells: 213.1;T-cells: 147.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 29.3;HDLM-2: 16.0;HMC-1: 13.0;JURKAT: 22.2;Karpas-707: 15.7;RPMI-8226: 19.8;RPTEC TERT1: 22.6;U-266/70: 14.8;U-266/84: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002969, CAB025882, CAB055513" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB025882: , CAB055513: , HPA002969: AB_1079870" "prognostic favorable (5.07e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-2)" "unprognostic (1.80e-2)" "unprognostic (2.28e-2)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.57e-2)" "unprognostic (8.39e-2)" "unprognostic (1.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.71e-1)" "unprognostic (5.71e-2)" "unprognostic (6.20e-2)" "unprognostic (2.72e-1)" "unprognostic (1.94e-1)" "prognostic favorable (3.14e-4)" 1.4 6.4 0.1 11.2 0.2 6.5 8.3 0.0 0.2 10.1 0.0 3.4 2.7 3.8 17.2 1.7 13.7 3.6 0.5 0.3 0.5 11.9 3.1 5.4 28.7 0.9 0.2 0.8 5.4 13.8 9.8 0.5 0.4 1.0 4.6 0.0 6.1 6.2 0.2 0.8 5.3 1.1 1.4 12.2 4.9 9.5 0.2 35.8 1.0 0.5 26.6 6.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 29.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.1 22.2 0.0 15.7 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.8 22.6 0.0 0.0 0.0 1.7 0.0 0.2 0.0 7.8 0.0 0.1 0.0 0.1 0.0 0.0 14.8 11.2 0.0 0.0 0.0 0.0 12.6 0.7 1.8 171.0 0.5 144.2 15.9 139.7 155.6 0.7 54.5 121.2 135.4 3.7 121.0 1.1 0.9 268.9 126.8 0.1 0.2 0.0 0.2 0.3 0.5 0.9 0.2 0.4 1.4 0.2 0.3 3.1 3.2 10.5 1.0 27.1 2.0 0.1 0.0 2.8 0.1 9.7 5.3 0.8 0.0 3.1 9.2 0.0 0.1 107.1 0.5 46.9 0.5 58.1 12.3 1.6 2.4 1.2 9.0 7.0 2.0 0.1 1.1 7.7 14.0 120.1 0.0 7.5 28.7 0.3 0.0 1.4 1.1 0.0 5.4 3.1 156.1 1.5 3.8 1.8 12.2 2.6 1.6 213.1 0.5 1.6 1.3 0.3 0.7 31.0 0.2 0.8 2.0 1.5 0.3 6.6 0.7 1.1 46.4 9.9 0.7 1.3 0.3 147.0 1.2 0.3 0.6 SKIDA1 "C10orf140, FLJ45187" ENSG00000180592 "SKI/DACH domain containing 1" Q1XH10 10 21513475-21526368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.1;Early spermatids: 17.9" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.1;AN3-CA: 6.7;BEWO: 12.1;SH-SY5Y: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039208, HPA040439" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA039208: AB_10795034, HPA040439: AB_10796122" "unprognostic (5.36e-2)" "unprognostic (1.84e-1)" "unprognostic (5.32e-3)" "unprognostic (6.45e-4)" "unprognostic (9.97e-2)" "unprognostic (3.23e-3)" "unprognostic (3.61e-2)" "unprognostic (1.12e-2)" "unprognostic (1.59e-2)" "unprognostic (4.23e-1)" "unprognostic (9.35e-3)" "unprognostic (5.93e-2)" "unprognostic (3.38e-6)" "unprognostic (8.13e-2)" "unprognostic (1.50e-1)" "unprognostic (8.20e-2)" "unprognostic (8.52e-3)" 0.3 0.6 0.4 0.1 0.6 0.6 0.2 0.4 2.3 0.5 0.0 0.6 0.1 0.2 0.2 0.2 0.5 0.1 1.2 0.5 0.0 1.3 1.4 0.3 0.1 0.1 0.0 1.3 0.5 1.1 0.5 0.8 0.0 0.3 0.2 1.5 0.5 0.6 0.2 1.0 0.2 0.3 0.0 0.1 0.2 1.7 0.0 0.2 1.2 0.2 0.1 0.3 0.3 0.9 0.5 1.1 26.1 6.7 0.5 0.3 12.1 0.5 0.4 0.0 0.1 2.5 0.2 0.2 1.0 0.4 0.2 1.6 2.4 0.5 0.0 0.0 2.9 0.1 1.3 0.3 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.7 0.2 0.4 0.2 0.2 0.1 1.1 0.9 0.1 1.6 0.0 0.0 0.4 0.8 0.0 0.5 0.7 2.9 6.0 0.9 4.5 0.1 2.1 0.4 5.4 0.4 0.2 0.8 0.2 0.6 0.1 0.0 0.3 1.6 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.4 2.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.9 1.0 0.0 1.5 5.2 0.2 1.5 1.0 0.6 6.8 19.1 1.8 2.2 6.9 4.3 1.4 1.8 0.0 5.3 0.0 0.1 7.9 0.1 17.9 0.4 1.3 4.3 0.0 0.0 2.8 0.6 3.4 2.1 0.0 0.3 1.3 3.3 4.6 10.3 3.2 1.7 2.2 0.0 0.0 2.2 0.3 10.2 1.5 0.6 0.0 1.0 0.0 6.1 0.0 3.5 2.1 0.3 0.0 2.2 0.1 0.7 0.0 8.5 0.6 4.7 6.6 1.5 1.2 6.5 5.1 4.2 1.8 3.4 0.1 5.2 0.0 0.2 SKIV2L "170A, DDX13, HLP, SKI2W, SKIV2, SKIV2L1" ENSG00000204351 "Ski2 like RNA helicase" Q15477 6 31959117-31969751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047122, HPA051959, HPA054419" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Cytosol" "HPA047122: , HPA051959: AB_2681672, HPA054419: AB_2682482" "unprognostic (1.43e-1)" "unprognostic (5.75e-2)" "unprognostic (3.41e-2)" "unprognostic (1.66e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.36e-2)" "unprognostic (2.14e-2)" "unprognostic (7.75e-2)" "unprognostic (7.99e-3)" "unprognostic (1.53e-3)" "prognostic unfavorable (3.02e-7)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.20e-1)" "unprognostic (9.06e-2)" 21.9 33.1 0.0 5.2 0.3 4.1 21.6 0.0 0.4 26.5 0.0 25.1 10.5 22.6 9.4 23.0 25.0 0.0 22.0 0.0 0.1 24.0 54.7 22.2 3.4 0.0 0.5 24.6 25.7 2.4 39.7 2.6 0.0 31.9 2.4 2.1 22.4 3.2 20.4 20.2 31.2 5.7 0.0 40.6 27.6 16.6 0.1 4.3 27.7 5.3 2.7 23.6 20.9 0.0 0.2 12.7 13.3 0.0 16.5 11.8 27.1 10.9 11.7 13.6 13.2 0.4 0.0 0.0 26.0 25.5 13.2 11.9 0.0 30.8 9.9 14.8 15.7 0.0 0.0 0.2 0.0 0.1 0.2 28.3 17.9 0.1 0.0 12.7 0.0 19.3 0.0 13.6 0.0 0.0 0.0 0.3 20.6 0.0 0.0 0.3 0.0 0.0 11.2 0.0 0.0 0.0 23.6 0.0 17.6 11.5 0.0 15.7 12.8 16.0 7.2 18.7 0.2 42.2 35.7 12.0 20.4 0.1 0.0 0.3 0.5 0.2 1.5 1.4 1.1 0.2 0.7 0.3 1.1 0.9 0.8 0.8 0.1 0.0 2.2 0.5 0.2 0.4 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 6.4 16.0 11.3 10.1 13.3 2.8 5.0 7.9 11.4 5.0 9.3 5.1 8.5 10.0 8.8 7.3 8.4 12.6 12.7 19.7 1.9 9.5 3.1 7.7 7.9 7.9 12.6 6.5 7.2 8.6 7.9 7.4 28.1 6.3 8.2 10.8 8.6 19.4 9.2 0.0 5.0 13.2 8.2 6.3 4.1 1.5 9.3 7.8 7.2 2.8 10.2 4.9 18.6 3.0 4.8 9.4 16.0 6.0 20.2 5.9 25.5 6.9 16.5 8.3 0.0 4.1 10.2 4.7 7.5 6.6 3.7 12.4 14.4 12.3 11.0 5.2 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 414.0" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 381.0" "Cancer enriched" "Detected in some" 15 "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 79 "Hep G2: 58.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044343: AB_10961771" "unprognostic (8.46e-3)" "unprognostic (3.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.75e-2)" "unprognostic (7.33e-2)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (8.79e-3)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (1.26e-3)" "unprognostic (1.30e-3)" "unprognostic (3.78e-11)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" 0.3 2.7 4.8 0.0 7.0 0.0 0.3 4.8 8.0 0.3 2.7 0.0 0.0 0.3 0.0 1.1 2.1 0.0 0.1 5.3 7.9 0.7 414.0 0.0 0.2 6.8 6.1 0.6 0.3 0.0 0.8 0.0 5.4 0.0 0.0 1.7 38.0 0.0 0.0 0.1 0.0 0.0 4.8 3.3 0.0 2.3 8.4 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 58.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 7.0 4.8 8.0 5.3 7.9 6.8 6.1 5.4 4.8 8.4 3.9 0.4 0.0 0.0 24.8 4.8 0.5 0.6 0.6 1.2 0.6 0.1 0.1 0.9 7.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 1.9 0.0 24.0 0.3 0.5 0.1 0.4 0.0 0.1 0.0 0.9 16.8 381.0 0.0 0.0 0.2 0.0 0.0 23.2 1.1 0.4 0.6 0.3 0.0 1.9 0.0 7.0 0.0 1.5 0.1 16.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.6 0.0 0.5 0.5 2.4 2.8 1.2 0.4 0.1 1.0 7.8 0.0 0.3 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enhanced" "Detected in many" "Early spermatids: 86.8;Late spermatids: 229.3;Oligodendrocytes: 285.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" 7.3 3.4 17.7 4.5 28.9 9.6 8.4 25.4 25.0 9.1 1.8 18.4 20.7 4.1 12.2 23.7 11.0 4.9 3.6 16.2 18.6 7.7 18.1 8.3 4.4 29.9 29.7 4.1 15.5 27.1 8.8 8.5 30.4 18.6 14.8 4.8 14.6 2.4 8.9 17.1 22.4 2.8 22.1 6.3 26.5 11.5 30.2 7.2 5.6 7.8 5.9 4.3 15.5 50.9 4.3 10.1 20.1 22.6 7.2 7.8 26.6 0.7 0.3 1.2 0.5 22.5 0.7 1.0 2.5 4.8 18.2 6.1 4.2 10.8 0.4 3.5 13.1 10.4 3.9 18.9 1.0 0.7 0.6 2.0 21.3 19.4 1.0 4.3 0.7 5.4 9.6 5.3 0.7 5.3 1.0 2.4 7.1 23.2 3.9 2.2 1.3 18.1 0.1 26.9 2.4 0.3 5.7 7.8 7.0 20.9 31.8 0.2 5.6 12.0 4.0 15.9 2.6 12.7 0.2 0.4 21.2 0.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.2 17.7 28.9 25.4 25.0 16.2 18.6 29.9 29.7 30.4 22.1 30.2 50.9 22.6 6.4 17.5 46.7 1.0 11.6 5.0 18.7 4.6 8.0 9.5 8.1 2.8 10.0 18.0 5.5 8.4 16.1 0.5 43.3 0.0 2.9 86.8 11.6 2.5 8.2 4.2 11.0 59.9 8.0 1.3 1.9 39.8 4.1 0.0 13.1 6.4 12.7 12.9 0.0 67.4 49.7 12.2 13.0 3.0 229.3 1.8 4.8 3.6 77.8 6.4 8.6 0.0 45.8 285.5 6.1 20.5 0.7 0.4 13.9 34.3 4.2 42.0 3.5 0.0 4.5 2.6 2.5 1.2 10.3 12.6 9.2 1.3 0.1 25.3 4.5 SLC25A36 "FLJ10618, PNC2" ENSG00000114120 "Solute carrier family 25 member 36" Q96CQ1 3 140941830-140980995 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027036 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" Nucleoplasm "HPA027036: AB_1857048" "unprognostic (4.12e-2)" "unprognostic (9.98e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (6.52e-2)" "unprognostic (3.46e-1)" "unprognostic (9.00e-2)" "unprognostic (1.71e-2)" "unprognostic (1.99e-2)" "unprognostic (2.47e-2)" "unprognostic (3.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (6.03e-2)" "prognostic favorable (1.55e-4)" 27.1 22.2 16.6 14.3 16.2 61.6 33.5 16.2 22.7 31.9 13.9 25.7 30.9 34.4 47.7 15.0 32.6 18.4 39.8 16.1 20.1 38.7 4.2 27.5 21.3 17.0 16.4 39.0 45.2 28.9 26.9 26.4 17.5 27.1 19.5 42.6 23.4 20.8 38.4 22.5 22.9 19.2 16.9 20.1 34.0 23.8 18.2 20.6 31.8 20.8 17.6 23.0 23.9 21.5 52.3 11.5 36.0 30.8 33.0 40.7 46.2 19.4 23.6 18.2 27.3 28.6 24.0 42.1 46.9 17.3 31.2 34.9 40.1 15.2 40.6 33.8 36.5 33.9 29.8 20.9 45.9 48.8 21.3 44.1 61.1 15.4 45.8 44.4 22.0 32.0 17.6 27.4 29.2 22.8 30.6 34.1 37.8 12.8 18.4 34.2 32.0 59.6 23.5 17.7 22.4 38.2 26.7 45.1 80.9 30.3 32.6 29.2 24.1 29.5 17.1 52.2 19.0 56.4 36.8 51.2 36.0 21.1 15.0 10.7 9.2 15.1 9.6 11.5 11.8 16.3 9.6 10.2 14.0 15.1 13.5 12.6 1.7 18.3 13.5 9.7 9.9 9.8 16.6 16.2 16.2 22.7 16.1 20.1 17.0 16.4 17.5 16.9 18.2 21.5 60.3 99.3 143.0 85.5 47.6 68.2 68.0 38.1 116.7 106.0 72.2 77.5 90.3 38.6 52.0 71.7 133.5 58.8 58.2 22.7 64.6 26.4 10.6 113.4 78.0 45.8 59.3 27.3 127.7 38.3 38.0 73.9 58.1 106.3 65.9 92.8 35.7 0.5 26.5 92.5 115.6 32.5 30.5 38.2 45.8 16.0 59.7 38.4 56.9 46.9 36.9 68.2 25.7 108.6 109.1 29.3 22.8 59.5 48.2 88.9 44.9 57.5 98.8 121.8 59.2 80.0 59.2 59.4 68.8 61.3 54.4 49.4 49.1 83.2 46.8 78.9 SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" 12.2 36.5 27.4 8.9 24.8 16.4 11.8 14.1 23.2 16.3 21.9 12.1 7.2 11.6 8.9 7.5 13.5 7.6 7.1 21.1 45.5 19.1 10.2 18.8 14.1 27.8 33.3 22.5 10.6 11.8 35.1 9.0 30.1 16.8 4.1 11.6 11.3 9.2 5.9 13.0 11.2 6.0 17.7 22.6 10.0 4.8 42.2 3.4 24.8 3.6 5.6 11.6 12.1 17.4 0.7 12.4 14.3 11.1 7.1 5.2 16.1 6.7 8.4 15.6 9.4 13.6 2.5 0.1 13.1 7.4 11.3 4.4 8.0 5.2 6.1 15.7 14.4 0.0 17.5 13.5 18.6 0.0 2.2 9.5 8.4 7.5 3.4 1.4 13.3 2.7 6.4 16.8 9.3 11.6 0.6 0.3 6.5 3.5 11.7 0.5 1.6 5.7 14.2 13.6 5.4 16.9 6.8 17.0 18.3 22.0 20.4 0.3 9.9 11.8 6.9 10.4 0.9 17.8 7.4 1.8 6.2 0.0 10.1 0.0 1.0 0.0 0.7 0.4 1.1 0.2 1.2 1.0 0.6 0.1 1.9 0.8 0.0 0.0 0.1 0.0 1.7 0.9 27.4 24.8 14.1 23.2 21.1 45.5 27.8 33.3 30.1 17.7 42.2 17.4 8.8 6.4 13.4 22.2 3.9 4.6 8.9 5.0 5.2 27.2 9.6 9.9 2.5 5.7 5.6 12.9 58.4 14.5 5.6 3.2 1.9 7.5 0.6 7.1 7.0 12.4 10.2 2.7 13.4 6.0 8.8 8.1 3.6 11.6 1.3 15.4 8.2 2.2 15.2 3.3 17.2 3.2 8.2 11.4 10.5 0.7 17.1 15.1 3.6 12.2 4.2 22.8 5.2 12.1 13.3 3.4 3.9 12.4 2.2 9.0 7.0 6.0 4.4 40.8 32.9 6.4 7.7 0.2 5.3 2.4 4.7 26.0 8.2 16.4 2.6 5.3 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 92.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Paneth cells: 35.7;Proximal enterocytes: 43.4;Undifferentiated cells: 48.9" "Cancer enhanced" "Detected in many" "stomach cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA046068: AB_2679523, HPA055623: AB_2682866" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (6.85e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-4)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (8.95e-2)" 0.1 0.3 0.4 0.7 0.4 0.1 0.0 0.3 0.4 2.6 0.0 9.5 68.0 0.5 0.4 0.1 0.1 9.8 0.3 0.3 0.1 3.5 0.8 0.1 0.3 0.4 0.0 0.3 0.3 0.0 0.0 0.6 0.4 0.1 34.6 0.7 0.2 0.0 0.3 0.3 92.3 0.0 0.1 0.2 22.8 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.4 0.3 0.1 0.4 0.0 0.4 0.1 0.2 0.6 0.5 0.0 8.1 1.6 0.9 0.1 0.4 0.4 0.0 2.9 0.3 0.0 0.7 8.6 4.5 0.0 2.1 12.3 0.3 19.6 0.0 0.1 0.7 1.0 0.4 1.0 13.9 2.7 1.8 0.0 2.7 1.0 4.6 1.2 8.8 0.7 0.7 0.3 0.9 1.7 1.5 14.5 0.0 0.3 0.4 0.4 0.0 1.3 0.0 0.0 0.2 1.0 2.1 2.0 2.0 0.0 35.7 0.7 0.4 0.2 43.4 1.2 4.6 6.6 0.0 0.3 0.2 2.4 2.1 0.0 0.3 4.7 1.3 0.2 48.9 0.2 SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;epididymis: 68.5;testis: 35.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.4;Early spermatids: 17.8;Excitatory neurons: 15.6;Late spermatids: 42.4;Peritubular cells: 15.1;Spermatocytes: 16.6;Spermatogonia: 10.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Group enriched" "Detected in many" 10 "amygdala: 14.5;basal ganglia: 10.3;cerebral cortex: 18.2;hippocampal formation: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HAP1: 11.2;Hep G2: 12.0;REH: 22.8;RH-30: 11.0" "Group enriched" "Detected in all" 4 "amygdala: 130.7;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 6 "amygdala: 18.5;cerebral cortex: 55.5;hippocampal formation: 43.0" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" 0.1 2.1 14.5 0.1 10.3 0.3 0.1 0.0 18.2 0.2 0.0 0.1 0.0 0.4 68.5 0.1 0.3 0.1 7.9 22.2 0.0 0.1 0.2 0.2 0.5 0.5 0.0 0.2 0.0 0.5 0.3 0.0 0.8 0.3 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 35.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 1.5 0.4 1.3 0.1 2.0 0.2 0.2 0.3 0.0 0.0 1.3 1.4 0.5 0.5 0.0 0.1 0.0 8.8 0.3 11.2 0.0 0.3 0.0 1.2 5.9 0.5 12.0 0.2 0.2 2.3 0.0 0.0 0.6 0.0 0.2 0.9 2.9 1.7 0.1 0.2 3.9 0.1 0.4 1.8 0.4 0.0 22.8 11.0 1.4 0.0 0.3 0.0 0.7 2.8 0.0 0.0 0.1 0.0 0.8 0.1 0.3 5.1 0.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 14.5 10.3 0.0 18.2 22.2 0.0 0.5 0.0 0.8 0.0 0.0 1.5 0.3 0.0 0.0 2.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 17.8 0.0 0.1 0.4 0.0 0.0 15.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 42.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 15.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 16.6 10.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC31A2 "COPT2, CTR2, hCTR2" ENSG00000136867 "Solute carrier family 31 member 2" O15432 9 113150976-113164140 "Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 571.4;salivary gland: 409.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.4;Kupffer cells: 145.6;Macrophages: 101.3;monocytes: 84.1;Oligodendrocytes: 113.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 12 "classical monocyte: 226.0;intermediate monocyte: 331.9;myeloid DC: 134.6;neutrophil: 355.8;non-classical monocyte: 423.3" "Group enriched" "Detected in all" 47 "dendritic cells: 134.6;granulocytes: 355.8;monocytes: 423.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.4;hTCEpi: 85.0;hTERT-HME1: 57.7;LHCN-M2: 68.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014861 Approved Approved "Nuclear speckles,Plasma membrane,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Plasma membrane, Intermediate filaments" "HPA014861: AB_1857098" "unprognostic (2.26e-1)" "unprognostic (7.20e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (5.63e-2)" "unprognostic (3.31e-2)" "unprognostic (2.24e-1)" "unprognostic (3.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.86e-1)" "unprognostic (6.05e-3)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" "unprognostic (8.89e-2)" 48.2 16.7 45.0 18.4 72.6 20.1 24.4 68.2 77.8 7.3 34.2 11.3 10.8 4.4 16.7 9.3 6.9 8.6 10.3 45.1 54.0 27.8 33.4 27.4 16.1 76.6 65.8 5.1 19.2 571.4 2.5 23.6 71.4 4.4 12.1 0.8 409.1 42.6 16.7 48.2 17.2 10.8 61.5 32.7 11.8 13.8 61.7 12.1 6.3 14.6 17.6 13.3 10.7 108.2 7.8 3.1 1.3 1.7 54.4 22.3 6.5 4.0 13.9 12.8 12.3 2.4 1.5 0.3 0.5 9.1 7.9 37.7 5.1 31.0 12.0 2.2 1.3 0.1 1.2 3.3 20.7 1.9 0.8 25.3 85.0 30.0 57.7 1.8 6.9 3.0 1.4 2.6 68.9 6.5 1.6 0.7 0.4 1.8 2.6 0.2 39.3 0.0 4.5 4.2 0.9 2.5 6.9 36.4 1.4 0.8 8.6 2.5 2.4 2.0 1.9 13.7 3.2 2.1 5.0 0.1 12.5 3.2 2.0 5.1 226.0 24.0 4.3 331.9 6.5 1.2 4.9 5.2 134.6 1.0 3.8 3.9 355.8 1.0 423.3 2.1 3.0 104.9 45.0 72.6 68.2 77.8 45.1 54.0 76.6 65.8 71.4 61.5 61.7 108.2 13.8 9.6 9.2 2.3 7.0 37.1 6.4 37.7 13.6 7.0 15.3 10.8 0.6 4.3 10.9 1.8 35.5 96.4 3.6 12.8 3.9 13.5 4.1 23.5 4.9 6.4 3.5 0.4 2.1 7.7 9.0 14.4 3.6 8.4 0.0 2.7 12.8 18.1 57.2 6.7 1.8 4.5 10.2 145.6 65.6 4.6 15.8 101.3 0.0 4.7 84.1 6.9 3.1 0.5 113.7 18.5 11.0 9.4 9.1 10.2 51.3 18.2 14.8 9.1 19.7 8.7 7.8 31.0 5.2 3.3 38.4 43.1 7.9 4.6 5.7 7.6 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC35B1 UGTREL1 ENSG00000121073 "Solute carrier family 35 member B1" P78383 17 49700934-49709014 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048655, HPA057418" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA048655: AB_2680481, HPA057418: AB_2683432" "unprognostic (1.35e-1)" "unprognostic (2.15e-2)" "unprognostic (1.09e-3)" "unprognostic (6.36e-2)" "unprognostic (8.31e-2)" "unprognostic (2.86e-3)" "unprognostic (6.17e-3)" "unprognostic (4.39e-2)" "unprognostic (2.47e-2)" "unprognostic (4.00e-3)" "unprognostic (3.37e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (5.69e-7)" "unprognostic (6.28e-2)" "unprognostic (7.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-2)" 13.4 9.9 16.8 15.6 17.1 19.4 18.6 17.3 20.0 16.7 21.7 19.9 26.8 11.4 52.8 17.2 18.1 12.5 32.2 17.1 20.0 28.8 46.4 15.3 14.3 17.4 17.8 8.5 18.4 31.6 13.7 17.0 17.4 13.7 24.2 17.0 16.4 15.5 61.4 10.8 26.0 15.6 16.5 12.4 17.4 14.0 18.4 15.3 36.0 60.3 21.6 23.0 7.9 17.2 45.2 75.5 52.4 87.7 47.5 32.9 59.7 46.4 77.8 98.7 80.5 156.6 52.3 31.5 104.7 66.7 55.0 32.6 87.1 55.3 103.5 38.3 65.3 38.5 43.8 94.0 85.3 71.9 34.9 31.9 60.3 73.1 83.6 24.6 64.7 46.5 40.0 84.2 68.1 94.2 51.9 52.5 23.6 82.4 92.2 37.4 56.6 85.6 47.1 45.5 45.8 60.4 25.9 21.3 34.0 57.7 68.7 50.0 26.6 74.0 33.3 84.0 61.9 48.3 79.6 42.7 50.2 54.6 63.8 25.1 27.2 10.1 15.8 27.7 12.0 11.6 10.9 15.4 32.1 6.8 11.2 10.0 11.2 13.5 19.3 43.3 13.6 16.1 16.8 17.1 17.3 20.0 17.1 20.0 17.4 17.8 17.4 16.5 18.4 17.2 32.1 16.0 29.7 10.7 37.1 22.3 40.0 56.4 22.8 28.2 37.1 29.0 40.5 21.5 45.3 27.6 35.5 57.8 47.4 34.9 35.2 78.4 52.4 19.1 25.1 39.2 50.6 20.4 11.7 101.7 121.0 28.6 16.3 24.1 42.5 22.8 27.8 56.6 73.5 21.9 10.4 56.2 59.0 28.0 45.2 17.6 30.1 34.0 37.4 4.7 39.6 44.6 26.8 11.6 11.2 77.5 33.2 20.7 103.7 70.1 139.9 51.3 33.9 35.4 13.1 25.3 47.9 63.2 41.2 24.5 25.1 80.4 31.1 24.1 41.7 50.6 SLC35F1 "C6orf169, dJ230I3.1" ENSG00000196376 "Solute carrier family 35 member F1" Q5T1Q4 6 117907264-118317676 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3;retina: 13.2" "Group enriched" "Detected in some" 17 "Astrocytes: 380.0;Excitatory neurons: 394.8;Inhibitory neurons: 503.6;Oligodendrocyte precursor cells: 1344.6" "Cancer enriched" "Detected in some" 4 "glioma: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 47.8;WM-115: 81.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019576 Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Centriolar satellite, Cytosol" "HPA019576: AB_2190216" "unprognostic (1.46e-1)" "unprognostic (5.67e-2)" "unprognostic (7.08e-2)" "unprognostic (1.37e-3)" "unprognostic (3.31e-1)" "unprognostic (4.99e-2)" "unprognostic (1.39e-1)" "unprognostic (4.04e-1)" "unprognostic (3.64e-2)" "unprognostic (3.04e-2)" "unprognostic (4.44e-3)" "unprognostic (2.19e-1)" "unprognostic (8.83e-4)" "unprognostic (3.04e-3)" "unprognostic (6.03e-2)" "unprognostic (8.32e-2)" "unprognostic (2.02e-1)" 1.4 1.2 17.1 0.9 19.0 0.0 0.6 6.3 21.3 1.2 0.6 4.9 0.4 1.2 3.0 0.6 1.8 0.6 3.4 16.2 11.0 0.6 0.0 0.1 0.0 8.5 12.4 0.3 0.4 0.1 0.5 0.0 8.3 1.2 0.9 13.2 0.5 1.3 0.3 0.4 1.4 1.1 9.0 0.7 1.1 0.6 12.3 0.0 0.6 0.3 0.0 0.7 0.9 16.4 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 1.6 0.0 0.9 0.0 0.0 0.4 0.0 6.1 6.9 0.0 0.0 0.3 0.0 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 19.0 6.3 21.3 16.2 11.0 8.5 12.4 8.3 9.0 12.3 16.4 0.9 0.0 0.0 380.0 0.1 0.4 0.1 0.0 0.0 15.8 0.1 0.0 6.9 0.0 1.3 0.0 2.1 0.0 0.3 0.0 0.0 0.0 17.9 0.0 0.2 0.2 0.0 0.0 394.8 0.4 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 16.8 503.6 0.0 0.0 0.0 0.0 38.3 0.6 0.3 14.2 27.2 0.0 27.6 0.0 1344.6 10.3 0.0 0.0 1.2 0.1 1.0 0.0 0.1 0.0 2.2 0.0 1.1 5.4 3.0 2.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC36A4 "FLJ38932, PAT4" ENSG00000180773 "Solute carrier family 36 member 4" Q6YBV0 11 93144174-93197991 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017887 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Plasma membrane, Cytosol" "HPA017887: AB_2190238" "unprognostic (1.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.17e-3)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" "unprognostic (8.77e-2)" "unprognostic (1.08e-3)" "unprognostic (7.83e-3)" "unprognostic (3.06e-2)" "unprognostic (7.97e-2)" "unprognostic (2.09e-2)" "unprognostic (8.04e-3)" "unprognostic (7.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.74e-1)" "unprognostic (9.45e-3)" "unprognostic (4.20e-2)" 5.8 7.4 4.2 9.3 4.6 19.4 4.6 8.1 5.8 5.1 6.2 5.4 2.0 7.1 2.1 5.3 4.8 5.7 6.0 4.0 8.5 9.4 7.8 6.0 5.3 7.2 6.9 5.7 5.7 6.5 7.7 6.2 7.7 4.9 6.4 15.3 3.7 5.9 2.4 4.1 3.1 8.1 5.5 4.1 4.3 4.3 6.1 7.3 8.8 2.3 6.7 6.9 3.6 7.0 10.4 18.2 36.5 7.3 12.7 25.6 20.5 17.6 29.2 25.6 31.0 14.6 33.1 12.5 9.9 16.5 13.3 12.5 11.4 6.5 23.4 21.1 13.3 14.5 35.3 9.8 10.0 36.6 20.6 12.4 20.0 14.9 9.2 12.0 14.0 17.6 1.3 0.2 26.5 2.6 16.3 27.4 14.8 4.0 18.4 7.2 21.7 5.1 8.7 15.1 33.6 43.8 25.7 9.9 6.4 26.4 18.0 10.6 15.7 48.0 14.8 28.6 26.0 5.1 10.9 0.0 10.9 15.0 25.4 0.1 4.9 5.3 0.8 2.6 1.0 0.9 0.6 1.0 1.9 1.0 1.5 1.0 1.5 0.5 1.7 0.7 0.5 1.1 4.2 4.6 8.1 5.8 4.0 8.5 7.2 6.9 7.7 5.5 6.1 7.0 11.9 12.8 11.5 35.9 29.5 30.7 43.2 9.7 25.6 21.2 10.3 8.0 11.5 20.0 7.1 20.2 22.9 10.7 13.6 3.1 35.2 24.4 9.9 15.5 19.2 18.5 27.6 5.5 66.8 43.6 25.8 21.9 18.8 5.7 4.5 29.0 13.2 9.1 13.6 26.9 71.0 19.6 10.2 52.3 47.1 4.2 18.0 50.1 21.4 27.2 42.8 20.7 13.4 45.2 59.4 33.2 6.3 15.4 22.1 70.4 0.4 16.2 20.8 24.2 6.6 18.0 18.1 7.3 3.3 11.8 32.0 16.3 15.7 20.6 4.3 30.6 SLC38A5 "JM24, SN2" ENSG00000017483 "Solute carrier family 38 member 5" Q8WUX1 X 48458537-48470260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 237.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 196.3;Erythroid cells: 74.3;Exocrine glandular cells: 80.8;Pancreatic endocrine cells: 129.4;Plasma cells: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 214.0;HBEC3-KT: 326.7;HeLa: 300.0;hTCEpi: 237.8;Karpas-707: 282.8;RPMI-8226: 539.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047411 Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" Cytosol "HPA047411: AB_10964355" "unprognostic (2.81e-1)" "unprognostic (4.87e-2)" "unprognostic (7.92e-3)" "unprognostic (1.58e-1)" "unprognostic (1.29e-3)" "unprognostic (1.26e-1)" "unprognostic (7.75e-2)" "unprognostic (5.79e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.13e-4)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.27e-3)" "unprognostic (1.45e-1)" "unprognostic (2.86e-1)" "unprognostic (2.20e-1)" 4.2 1.9 29.9 13.0 21.8 55.7 2.5 22.6 26.3 9.4 10.6 13.2 13.3 4.2 2.7 10.2 4.9 3.7 6.1 21.6 22.5 1.8 0.9 25.3 8.8 30.4 23.1 6.7 237.2 0.4 0.9 1.1 28.0 5.6 16.2 3.4 9.3 8.6 0.6 21.3 9.2 7.0 22.0 13.8 15.9 0.7 30.4 8.5 20.3 1.3 9.1 9.4 8.7 21.1 143.0 0.3 0.1 1.6 2.8 11.6 0.3 9.4 0.0 0.3 0.1 0.4 0.3 147.8 0.2 61.7 0.3 214.0 164.4 326.7 0.0 47.4 0.2 80.7 300.0 102.4 23.2 166.7 0.2 22.0 237.8 2.9 0.6 0.2 2.8 35.5 150.7 282.8 32.2 0.2 36.3 57.9 74.2 0.0 0.7 131.5 0.7 539.6 0.0 0.1 13.1 0.7 0.1 0.9 0.2 1.1 0.5 6.9 4.7 0.6 0.4 0.4 0.4 0.4 1.0 53.0 1.6 0.8 0.7 0.1 0.4 0.4 17.3 0.6 24.2 11.4 18.6 16.4 2.3 8.9 8.7 11.3 0.5 9.6 0.1 13.1 21.7 9.1 29.9 21.8 22.6 26.3 21.6 22.5 30.4 23.1 28.0 22.0 30.4 21.1 2.3 0.0 0.6 0.3 15.4 26.6 2.7 196.3 17.1 3.2 0.2 0.3 0.4 0.0 33.6 5.5 18.8 0.2 6.7 9.9 0.0 5.5 0.4 1.1 9.1 11.8 0.0 74.3 0.3 80.8 0.6 8.9 3.6 2.7 4.5 1.0 0.4 0.4 2.4 0.0 0.5 17.5 4.1 0.3 3.9 1.3 2.5 2.1 8.8 32.8 1.8 0.3 8.2 0.5 0.2 129.4 5.5 1.2 62.3 4.5 1.2 0.0 4.2 0.3 0.0 0.7 4.6 0.1 0.4 6.4 8.5 0.0 9.5 4.6 21.4 1.9 SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61083733 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 178.2;Excitatory neurons: 98.8;Hofbauer cells: 100.3;Inhibitory neurons: 77.4;Late spermatids: 124.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" 7.6 9.1 6.0 4.7 6.6 2.9 7.4 6.1 9.5 7.3 8.9 4.8 3.1 5.1 13.2 3.3 5.6 9.9 3.7 6.9 6.5 12.0 6.3 8.6 7.8 5.4 6.0 5.8 3.4 21.3 7.2 9.6 6.0 5.1 6.6 7.5 5.9 3.9 2.1 2.9 3.5 5.3 5.0 6.6 3.8 5.0 7.4 5.0 6.3 3.0 4.8 7.0 5.0 6.7 16.2 21.5 6.8 12.3 68.7 25.3 4.9 11.6 34.5 10.7 10.2 5.4 41.0 4.0 19.2 10.6 22.5 13.5 6.8 11.9 9.8 6.0 3.2 6.7 8.6 14.2 22.7 3.7 12.1 19.9 4.9 10.5 12.2 43.2 14.3 6.8 9.3 8.4 37.5 9.2 6.6 8.4 4.0 9.5 14.3 1.6 20.1 11.9 30.7 8.5 3.3 3.0 9.9 7.0 19.1 9.3 10.4 5.8 15.6 16.4 7.1 20.0 6.5 1.6 4.9 1.6 34.0 3.0 13.1 0.0 6.6 0.1 1.7 7.1 2.2 2.2 3.1 2.4 3.6 2.0 2.7 3.4 0.2 0.8 4.5 4.4 4.5 2.8 6.0 6.6 6.1 9.5 6.9 6.5 5.4 6.0 6.0 5.0 7.4 6.7 6.8 22.4 6.7 31.6 6.0 5.2 11.4 14.6 8.0 19.7 7.2 7.5 4.3 7.2 10.0 5.5 22.9 5.6 4.9 2.6 1.9 5.3 178.2 13.0 11.0 7.2 4.2 3.4 98.8 2.8 9.4 11.2 5.1 6.2 6.3 7.3 4.2 4.6 100.3 5.0 77.4 3.1 6.1 24.8 10.0 124.4 10.8 26.2 5.4 20.6 6.4 11.7 2.1 54.3 30.8 7.4 1.9 6.0 5.8 6.6 3.3 23.1 40.4 24.9 0.0 12.3 9.1 16.6 11.5 6.4 2.8 6.7 7.8 5.0 2.8 6.9 SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.8" "Group enriched" "Detected in all" 13 "Early spermatids: 271.8;Late spermatids: 753.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: AB_10796782, HPA049428: " "unprognostic (2.16e-3)" "unprognostic (2.30e-2)" "unprognostic (6.23e-3)" "prognostic favorable (6.87e-4)" "unprognostic (3.49e-1)" "unprognostic (8.08e-3)" "unprognostic (9.76e-3)" "unprognostic (6.34e-3)" "unprognostic (1.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.77e-1)" "unprognostic (4.90e-2)" "prognostic favorable (2.87e-4)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (7.50e-2)" "unprognostic (4.93e-3)" 6.0 11.4 7.5 6.0 7.8 2.6 5.3 6.0 8.9 5.1 6.1 5.1 4.3 5.5 6.2 6.5 4.0 5.6 15.9 7.9 7.4 7.3 13.6 5.4 4.3 7.7 7.6 4.6 4.8 14.1 7.2 7.5 8.1 5.5 5.9 4.7 6.2 4.6 9.4 5.3 5.5 7.4 5.8 10.3 5.4 32.8 9.8 3.6 7.8 8.3 4.6 5.4 4.9 7.0 6.9 10.9 10.8 16.5 22.0 12.9 19.3 16.2 18.7 22.7 15.6 9.9 11.0 4.5 8.9 22.9 17.9 15.9 10.2 11.7 13.3 2.8 9.4 5.1 9.3 16.5 32.9 10.6 14.0 25.9 23.6 16.1 10.3 12.3 23.5 10.4 14.9 6.3 16.7 8.0 4.3 6.3 11.7 7.5 16.0 15.2 11.6 12.1 10.0 15.4 7.9 11.3 25.7 17.0 7.0 14.4 7.6 4.2 18.7 12.3 9.3 21.8 5.0 9.7 6.7 5.2 16.8 6.3 9.3 0.1 6.8 2.0 4.0 6.6 2.2 1.3 2.4 2.9 4.5 2.5 1.9 2.1 0.5 1.8 6.4 1.7 1.8 5.5 7.5 7.8 6.0 8.9 7.9 7.4 7.7 7.6 8.1 5.8 9.8 7.0 3.3 3.2 4.4 7.8 2.0 3.8 4.0 4.4 1.2 9.8 4.7 3.2 12.8 4.3 4.8 11.0 12.5 8.4 5.0 3.7 3.9 14.0 271.8 3.5 6.8 6.2 13.1 2.1 13.3 8.5 9.5 5.1 9.7 6.0 1.3 10.7 8.2 9.3 38.6 16.8 15.5 3.1 12.2 10.1 8.2 753.3 9.6 11.6 8.8 9.4 4.0 7.1 8.2 5.0 7.6 12.8 2.7 8.6 1.8 3.7 4.8 5.9 3.8 7.1 6.6 4.8 5.1 6.9 7.6 4.6 4.3 15.3 2.7 8.6 4.9 3.2 SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 48.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 170.8;Microglial cells: 362.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: AB_2675165, HPA036513: AB_10670801, HPA066087: AB_2685613" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (5.33e-2)" "unprognostic (1.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (7.40e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (2.10e-2)" "unprognostic (8.73e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (8.46e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-2)" "unprognostic (3.68e-1)" "unprognostic (2.47e-2)" "unprognostic (6.89e-2)" 8.2 9.7 7.9 6.3 7.4 4.6 7.1 0.0 21.0 10.8 0.0 4.3 3.9 11.0 3.7 3.6 9.5 8.8 4.3 15.8 0.0 8.7 2.0 7.4 8.3 0.1 0.4 7.9 4.8 5.2 1.1 12.8 1.7 19.1 4.2 5.1 3.7 6.7 1.3 7.0 4.0 7.7 1.4 18.3 5.0 9.3 9.9 10.6 48.4 3.1 7.6 6.3 2.1 5.8 7.3 27.1 46.8 13.0 9.5 21.1 24.3 34.8 16.4 16.1 8.1 38.4 26.4 10.4 51.3 19.6 12.4 10.4 28.6 31.6 19.9 5.4 21.8 11.7 37.1 34.0 10.8 45.4 4.9 12.9 5.1 17.7 20.2 56.9 37.3 10.5 34.9 14.3 26.7 7.3 12.7 14.0 53.8 44.1 18.8 28.9 16.6 27.0 74.8 12.7 17.5 24.7 34.4 65.1 18.7 81.2 11.2 26.5 36.1 28.7 33.6 19.0 18.7 4.6 3.7 6.3 24.5 19.9 29.9 41.5 4.7 3.7 7.5 4.4 6.1 12.3 6.8 6.7 6.4 15.8 6.0 7.8 0.8 21.7 3.3 32.8 7.6 2.6 7.9 7.4 0.0 21.0 15.8 0.0 0.1 0.4 1.7 1.4 9.9 5.8 72.1 3.2 12.8 40.8 42.0 25.6 12.1 51.3 13.1 23.0 16.9 23.1 7.6 5.7 33.2 36.8 8.4 49.3 60.2 4.3 1.9 17.7 28.5 13.2 48.7 75.4 15.6 26.9 170.8 11.3 66.0 35.3 11.2 16.5 13.3 25.7 26.4 2.8 24.5 8.4 78.3 5.9 26.4 20.7 27.1 16.0 19.0 31.8 7.2 362.6 16.2 17.0 20.6 49.3 49.5 24.3 2.8 18.8 21.3 20.1 4.5 14.7 9.5 20.0 13.1 41.9 29.1 61.3 33.6 7.5 20.5 23.4 35.4 30.8 6.2 7.8 SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 551.3;pancreas: 252.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 266.7;Hepatocytes: 611.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 321.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" 63.5 72.4 13.0 35.5 11.0 1.4 39.8 11.9 13.1 17.3 39.7 48.2 142.2 30.2 6.2 11.6 25.9 32.0 76.7 14.5 22.9 30.8 551.3 23.9 7.6 43.0 30.4 27.7 252.7 12.9 21.5 19.0 25.7 22.3 50.3 18.6 21.8 18.7 43.0 20.0 84.9 33.0 13.3 8.1 80.5 26.5 25.3 6.0 87.7 17.4 6.9 56.0 14.5 14.8 51.8 68.3 18.4 37.6 65.1 54.7 40.1 72.8 321.0 111.3 173.5 226.9 47.9 51.1 39.9 86.1 288.9 55.6 92.8 91.1 181.9 53.1 49.2 40.8 51.0 230.7 154.3 28.5 43.2 58.4 72.6 198.0 136.9 56.3 50.5 36.5 36.2 51.2 57.3 24.0 43.4 18.2 113.4 81.9 49.8 60.1 34.9 110.8 40.8 22.3 31.3 48.7 74.3 31.3 151.4 39.7 25.1 39.4 28.0 137.3 69.2 87.4 75.7 29.2 28.7 66.9 194.3 37.7 81.9 0.0 0.4 2.1 6.7 0.1 7.2 4.0 3.8 5.0 1.5 1.9 4.3 5.9 0.1 2.7 0.1 0.7 3.4 3.4 13.0 11.0 11.9 13.1 14.5 22.9 43.0 30.4 25.7 13.3 25.3 14.8 12.4 3.2 7.7 11.4 9.1 33.3 11.5 10.8 18.8 7.8 20.3 16.6 66.6 41.5 3.8 7.3 2.1 0.4 3.6 91.6 1.9 47.6 0.5 136.1 58.3 32.2 33.4 10.5 26.2 74.7 2.7 58.8 47.9 266.7 0.0 20.8 29.6 611.4 1.8 48.8 24.6 60.6 6.1 15.4 25.8 3.2 23.9 2.9 44.4 6.5 2.7 5.2 2.1 9.0 3.9 47.3 39.1 41.8 13.5 26.5 75.6 24.6 1.1 8.2 0.0 47.1 32.2 0.7 3.0 4.1 21.0 0.5 7.4 14.7 43.5 9.4 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC40A1 "FPN1, HFE4, IREG1, MTP1, SLC11A3" ENSG00000138449 "Solute carrier family 40 member 1" Q9NP59 2 189560590-189583758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 489.8;Kupffer cells: 1340.2;Syncytiotrophoblasts: 2463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 326.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 509.0;CACO-2: 123.1;HEL: 430.0;HMC-1: 110.5;T-47d: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065634 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA065634: AB_2685524" "unprognostic (1.28e-2)" "unprognostic (1.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.83e-2)" "unprognostic (8.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.66e-1)" "unprognostic (6.22e-2)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "unprognostic (6.43e-2)" "unprognostic (6.44e-2)" "prognostic favorable (8.55e-5)" "unprognostic (4.66e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.11e-2)" 59.6 333.5 9.3 52.6 11.9 45.8 97.7 9.6 9.8 156.3 10.4 124.7 289.3 95.4 61.6 30.5 214.2 148.7 52.6 7.2 12.0 79.9 251.5 122.9 172.6 15.6 15.7 317.2 53.2 91.8 19.0 250.1 12.8 39.5 130.8 29.5 58.7 53.1 64.2 12.2 127.9 69.3 15.5 368.1 96.8 33.2 13.9 62.6 68.0 60.3 59.1 53.1 21.8 11.3 0.0 7.4 0.6 0.0 509.0 3.3 25.4 0.2 6.6 1.9 3.1 123.1 0.4 0.2 1.0 0.2 1.4 0.4 2.4 0.3 1.6 0.3 1.7 430.0 1.7 45.8 1.9 1.5 110.5 35.9 0.2 1.2 0.0 11.7 13.0 16.4 44.6 1.1 6.3 0.0 18.2 28.8 1.5 92.7 1.7 0.2 5.0 2.5 5.3 18.1 1.0 5.4 0.8 35.4 0.0 39.5 207.6 6.2 0.3 0.8 11.7 0.5 0.1 1.1 0.2 0.3 0.1 0.2 0.1 129.8 101.5 172.1 2.2 23.7 3.2 0.2 54.4 4.9 115.6 0.7 80.2 17.8 326.2 4.6 2.6 18.8 5.3 105.8 9.3 11.9 9.6 9.8 7.2 12.0 15.6 15.7 12.8 15.5 13.9 11.3 44.2 125.0 40.3 3.6 12.0 9.2 51.3 10.5 19.9 4.8 83.8 30.0 48.0 138.7 31.6 33.1 4.2 489.8 5.7 328.9 49.0 54.7 10.5 39.6 38.2 39.8 18.6 253.7 0.3 71.8 20.3 81.9 76.5 129.5 9.5 12.8 245.9 259.7 86.4 6.7 6.8 60.8 6.1 1340.2 26.8 9.2 121.2 172.7 8.8 34.7 41.7 17.5 2.1 14.6 0.2 71.5 86.2 58.6 4.1 26.2 163.0 150.0 34.4 48.4 65.7 13.7 49.1 7.4 3.9 12.5 8.1 2463.5 11.9 84.8 48.9 27.7 SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 128.6;pancreas: 233.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Erythroid cells: 82.9;Exocrine glandular cells: 35.4;Hepatocytes: 138.2" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;NB-4: 74.3;U-937: 70.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" 13.9 10.7 3.6 4.7 4.2 35.7 11.1 2.7 5.0 13.1 2.7 15.7 8.7 12.6 10.3 4.4 13.5 18.2 8.6 3.6 2.8 7.3 128.6 9.9 7.4 3.8 3.2 20.3 233.2 1.8 4.4 6.3 3.5 12.8 9.4 1.3 13.8 6.2 17.1 18.8 9.2 8.7 2.7 8.5 30.4 3.4 3.4 2.1 12.7 9.1 6.6 16.2 9.9 3.9 1.1 1.7 1.8 20.3 25.7 18.8 0.2 10.4 13.8 3.0 7.6 6.5 2.8 59.5 2.7 7.9 3.9 1.0 18.1 1.2 3.7 2.8 4.6 30.9 0.5 62.7 33.7 54.3 7.2 23.8 4.4 5.2 23.2 7.3 13.4 34.7 43.9 10.7 3.8 2.3 0.5 74.3 6.6 27.0 13.6 51.0 9.8 27.2 0.5 0.1 23.5 3.6 1.9 0.3 23.8 0.5 1.6 27.3 5.5 3.1 7.1 26.2 1.7 12.1 4.3 35.3 1.5 70.6 4.2 11.1 6.2 0.7 10.9 2.4 9.2 2.9 4.9 7.7 8.4 1.5 4.9 6.9 0.5 7.5 0.2 1.9 9.5 5.5 3.6 4.2 2.7 5.0 3.6 2.8 3.8 3.2 3.5 2.7 3.4 3.9 4.4 0.0 7.3 1.6 3.3 7.0 1.6 0.0 3.4 5.7 1.8 2.4 6.8 47.1 0.6 0.0 0.0 0.2 3.6 3.1 3.9 3.4 21.5 5.3 6.0 4.7 6.0 82.9 3.5 35.4 0.4 10.9 4.6 13.4 3.8 1.3 15.4 138.2 7.4 0.0 1.4 8.8 0.0 8.1 2.9 14.8 15.5 3.2 5.4 5.6 1.3 0.2 5.2 4.0 0.6 11.1 2.9 7.9 6.2 3.2 0.3 0.1 0.7 0.4 6.6 6.4 7.7 0.7 1.5 0.3 3.7 0.1 6.4 2.9 9.0 0.9 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0;liver: 96.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 53.2;Hepatocytes: 51.3;Proximal enterocytes: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.0;T-47d: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" 13.8 11.7 5.1 10.2 5.7 2.9 10.0 7.7 5.2 14.7 10.0 19.8 46.7 5.6 11.1 4.0 7.5 23.8 12.3 4.7 5.7 18.2 96.0 11.5 16.3 5.9 6.0 3.9 6.7 23.9 10.2 9.5 6.1 6.5 18.8 15.9 9.0 9.9 8.5 4.2 76.0 8.2 6.6 18.2 7.8 11.0 6.6 11.6 12.5 8.6 11.1 7.0 2.2 5.6 0.0 2.8 0.0 7.6 6.0 2.3 0.2 2.7 15.7 3.0 4.4 0.1 6.6 5.2 4.7 4.0 11.5 0.6 3.5 1.4 4.5 3.9 6.2 3.6 0.0 0.0 11.4 0.0 4.3 9.8 2.9 4.5 7.3 3.0 5.6 15.7 3.9 0.0 14.5 3.0 8.6 0.6 0.3 8.0 2.2 3.5 13.3 0.2 27.0 0.9 1.2 0.4 0.0 14.1 5.7 3.1 20.6 4.6 2.0 1.4 2.7 0.4 16.0 4.0 2.0 0.8 0.9 0.0 2.8 33.1 8.9 3.8 10.3 13.1 8.6 7.4 8.0 10.1 11.7 9.7 11.4 10.8 9.8 7.0 19.4 11.0 10.6 8.7 5.1 5.7 7.7 5.2 4.7 5.7 5.9 6.0 6.1 6.6 6.6 5.6 6.2 0.0 5.4 16.0 14.5 1.9 0.1 7.4 1.8 33.7 15.1 3.3 9.6 17.2 15.6 9.2 8.4 0.6 16.4 49.0 1.9 15.5 4.6 2.1 1.7 12.2 3.6 4.6 11.6 5.6 0.3 6.2 0.0 2.1 25.9 53.2 17.5 51.3 10.8 21.9 13.0 6.8 2.0 32.1 36.6 1.8 1.5 22.5 7.2 16.9 9.3 14.2 12.3 14.6 15.6 3.5 5.3 2.2 6.5 0.6 125.0 10.1 15.4 9.8 0.0 2.8 7.2 2.6 0.9 4.9 1.7 0.7 11.4 16.8 13.9 0.2 SLC4A1AP "HLC3, kanadaptin" ENSG00000163798 "Solute carrier family 4 member 1 adaptor protein" Q9BWU0 2 27663471-27694976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036679 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA036679: AB_2675244" "unprognostic (5.63e-2)" "unprognostic (1.01e-1)" "unprognostic (4.62e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.21e-1)" "unprognostic (7.89e-3)" "prognostic unfavorable (3.76e-7)" "unprognostic (1.32e-1)" "unprognostic (7.74e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-1)" "unprognostic (9.66e-2)" "unprognostic (9.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.79e-4)" 13.7 16.6 15.3 16.1 16.2 15.8 14.5 17.9 20.9 11.8 12.7 12.3 12.6 13.4 12.4 15.1 12.7 10.4 20.6 16.4 16.2 16.0 16.2 13.9 17.4 15.7 15.6 15.5 14.4 21.1 12.7 15.7 15.7 12.9 12.9 19.8 12.9 12.0 30.6 16.4 13.3 13.2 13.3 15.0 13.9 33.9 15.6 17.1 15.3 22.1 16.9 12.6 12.0 16.4 44.6 25.4 25.1 23.6 25.3 23.2 36.8 36.1 24.8 37.2 30.3 37.4 31.7 28.0 32.7 29.1 39.2 31.0 40.6 28.0 33.2 39.2 33.2 32.2 26.2 41.5 30.7 46.6 29.5 20.9 34.8 37.1 34.8 31.2 38.4 27.1 47.5 29.7 34.7 27.1 31.5 45.4 25.4 29.3 24.7 25.9 54.9 32.4 38.5 20.4 27.2 26.8 28.1 37.9 36.0 25.2 23.0 30.1 39.3 34.5 31.3 24.2 42.7 48.5 73.8 88.4 37.4 36.8 28.2 104.8 33.4 48.9 31.6 32.6 31.8 26.1 28.6 28.0 25.8 36.7 34.5 29.1 31.9 43.7 37.6 20.8 34.9 28.0 15.3 16.2 17.9 20.9 16.4 16.2 15.7 15.6 15.7 13.3 15.6 16.4 17.1 32.1 28.9 14.7 17.3 11.9 12.3 27.1 14.8 19.9 13.3 11.0 30.1 11.5 29.1 18.4 18.8 24.5 21.0 11.4 5.9 28.4 47.2 22.0 20.3 21.9 16.3 11.8 25.5 36.9 20.3 17.4 13.3 20.4 38.6 18.5 15.4 13.9 24.4 25.2 23.7 11.5 16.2 13.9 8.2 7.9 17.4 18.9 17.8 8.4 31.5 21.6 19.6 12.5 18.2 30.5 9.3 19.2 22.1 8.7 11.5 16.1 24.4 21.1 32.9 23.3 21.7 143.4 82.4 15.7 11.9 24.4 21.8 21.5 10.1 10.8 SLC4A2 "AE2, BND3L, EPB3L1, HKB3, NBND3" ENSG00000164889 "Solute carrier family 4 member 2" P04920 7 151057210-151076526 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 492.1" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019339 Enhanced Uncertain "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Plasma membrane" Cytosol "HPA019339: AB_1844825" "unprognostic (1.19e-1)" "unprognostic (3.33e-3)" "unprognostic (8.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (9.04e-6)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (3.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.26e-4)" "unprognostic (4.67e-3)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-2)" 28.4 34.8 16.9 19.2 29.4 12.7 23.7 29.1 21.9 38.9 492.1 45.0 22.5 40.3 4.9 21.0 31.1 19.7 31.3 39.4 23.2 38.6 52.3 33.2 13.1 32.8 27.9 31.9 52.5 72.4 13.8 27.0 32.0 28.2 7.1 4.7 23.1 14.0 18.8 21.7 29.3 16.5 20.2 27.0 82.2 13.7 32.7 12.4 25.4 12.3 6.3 31.9 25.8 40.2 60.9 196.9 37.8 78.9 37.6 17.9 87.1 72.9 37.0 56.9 48.0 113.0 91.6 35.8 154.1 35.0 84.6 58.2 38.2 31.4 9.8 105.3 59.1 48.5 91.9 57.5 59.6 25.2 147.0 29.0 27.4 65.6 15.7 60.9 31.3 50.6 151.8 27.1 44.3 118.0 69.2 43.3 90.4 80.7 73.2 55.2 21.2 42.2 44.6 41.0 31.5 113.9 67.0 118.4 62.0 27.3 51.2 46.7 72.0 78.1 39.1 77.5 106.5 31.2 47.7 20.5 118.7 61.4 160.6 0.0 1.6 0.4 0.8 1.6 0.7 0.9 0.7 0.7 1.0 0.3 0.7 0.8 0.2 0.1 1.0 2.1 0.2 0.9 16.9 29.4 29.1 21.9 39.4 23.2 32.8 27.9 32.0 20.2 32.7 40.2 15.6 9.6 8.2 9.8 7.2 11.1 5.9 13.6 15.4 7.7 14.5 11.9 4.0 18.6 9.6 20.2 25.0 36.1 14.2 17.6 17.6 35.7 1.0 21.9 18.9 13.6 27.6 2.5 0.4 35.8 9.4 13.6 30.1 17.0 47.1 62.1 17.9 34.6 26.0 15.2 1.4 12.1 16.2 16.1 12.0 1.6 13.7 17.0 26.6 4.7 11.6 21.6 3.1 3.0 16.8 43.8 14.0 19.9 9.9 5.9 24.9 19.1 11.4 8.2 13.1 12.8 17.6 3.1 7.9 10.6 7.0 91.5 8.5 11.2 22.1 4.5 SLC4A7 "NBC3, SBC2, SLC4A6" ENSG00000033867 "Solute carrier family 4 member 7" Q9Y6M7 3 27372721-27484420 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 57.6;retina: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 733.9;Rod photoreceptor cells: 704.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "hTERT-HME1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022494, HPA035857" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Focal adhesion sites, Cytosol" "CAB022494: , HPA035857: AB_10795135" "unprognostic (2.94e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-3)" "unprognostic (1.91e-1)" "unprognostic (8.48e-3)" "unprognostic (2.68e-1)" "unprognostic (6.79e-4)" "unprognostic (4.13e-2)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (8.58e-3)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.09e-2)" "unprognostic (6.68e-2)" "unprognostic (1.93e-1)" "unprognostic (7.26e-2)" 8.6 5.1 3.2 9.0 5.2 4.0 18.7 3.4 16.9 10.5 1.6 16.2 57.6 6.4 8.2 8.6 6.0 13.7 7.8 19.3 2.5 12.7 3.9 8.3 11.2 0.5 3.2 6.8 3.4 1.7 3.4 5.8 0.6 7.9 7.4 72.9 5.8 8.7 5.0 4.6 17.4 6.6 1.8 7.0 6.0 7.1 4.4 5.8 4.9 27.2 10.3 12.1 8.8 2.6 13.0 23.8 21.0 9.8 9.6 17.2 15.0 43.3 20.0 16.3 12.6 6.5 6.6 29.4 3.6 16.8 15.7 5.5 20.2 21.1 25.7 25.1 6.6 13.5 15.4 7.1 16.5 30.9 11.3 13.7 9.0 24.8 78.9 34.2 27.1 19.0 9.1 10.1 33.8 4.7 31.1 7.2 13.8 1.6 23.4 21.0 16.7 5.9 38.1 9.2 5.3 13.1 19.7 14.4 6.9 17.9 32.9 11.8 19.0 38.2 10.6 26.7 33.7 3.8 4.3 16.6 33.3 21.4 17.8 0.0 0.2 0.0 1.0 0.2 0.7 0.4 1.3 1.4 0.5 0.5 0.5 0.9 0.0 1.0 0.3 0.7 1.2 0.3 3.2 5.2 3.4 16.9 19.3 2.5 0.5 3.2 0.6 1.8 4.4 2.6 30.0 0.0 11.2 10.7 37.5 29.3 39.5 23.4 11.4 130.2 72.4 30.4 23.1 21.5 22.8 62.5 733.9 5.8 51.8 5.5 9.8 15.5 10.2 73.6 40.7 53.6 38.2 7.2 46.2 7.1 29.3 52.2 15.8 124.1 23.5 24.6 17.5 6.2 17.0 6.7 88.7 58.5 36.7 48.4 61.6 7.6 9.0 46.5 35.6 185.5 26.7 45.7 20.6 60.8 20.9 19.1 23.4 9.8 27.8 93.1 142.5 10.2 9.6 704.2 39.5 56.4 43.7 40.0 21.7 21.7 30.7 8.1 56.1 19.0 26.7 35.2 SLC4A9 AE4 ENSG00000113073 "Solute carrier family 4 member 9" Q96Q91 5 140360194-140375141 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "kidney: 35.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 2.4;Inhibitory neurons: 2.4;Ionocytes: 2.0;Oligodendrocyte precursor cells: 1.5;Oligodendrocytes: 6.4;Spermatocytes: 1.7;Spermatogonia: 1.9" "Cancer enriched" "Detected in single" 8 "renal cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051307 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA051307: AB_2681434" "unprognostic (1.68e-1)" "unprognostic (4.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "unprognostic (1.02e-2)" "unprognostic (3.28e-3)" "unprognostic (2.78e-1)" "unprognostic (2.47e-1)" "unprognostic (4.78e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (3.06e-2)" "unprognostic (5.04e-2)" "unprognostic (1.82e-2)" 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.5 35.5 0.0 0.1 0.0 0.9 0.6 0.0 0.1 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.7 0.3 0.5 0.9 0.6 1.0 0.5 0.6 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 6.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.0 1.7 1.9 0.0 0.1 0.0 0.1 0.1 0.1 0.2 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 SLC5A7 "CHT1, hCHT" ENSG00000115665 "Solute carrier family 5 member 7" Q9GZV3 2 107986523-108013994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter biosynthesis, Sodium transport, Symport, Transport" "Congenital myasthenic syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 32.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Club cells: 3.1;Respiratory ciliated cells: 1.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "RT4: 3.6;SCLC-21H: 1.0" "Group enriched" "Detected in many" 4 "basal ganglia: 23.1;hypothalamus: 9.0;midbrain: 9.4;pons and medulla: 14.4;thalamus: 6.2" "Group enriched" "Detected in many" 6 "basal ganglia: 20.4;pons: 26.5;spinal cord: 46.7" HPA046105 Approved "Nuclear bodies,Cell Junctions,Intermediate filaments" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 15: RT4 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Intermediate filaments" "Nuclear bodies" "HPA046105: " "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-3)" "unprognostic (7.10e-2)" "unprognostic (1.66e-1)" "unprognostic (3.39e-4)" "unprognostic (1.05e-2)" "unprognostic (9.78e-3)" "unprognostic (6.42e-2)" "unprognostic (1.61e-2)" 0.1 0.7 1.1 0.5 3.0 0.0 0.1 0.0 10.3 0.7 1.0 2.6 0.7 0.1 0.1 0.3 0.1 0.1 0.3 0.2 5.3 0.3 0.0 0.2 0.0 20.2 21.2 0.2 0.1 0.0 0.0 0.0 32.9 0.3 0.7 0.9 0.3 1.1 0.0 0.0 0.8 0.7 2.8 0.0 0.5 0.1 1.6 0.0 1.2 0.1 0.0 1.3 0.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 10.3 0.2 5.3 20.2 21.2 32.9 2.8 1.6 7.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 153.1" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 324.9" "Cancer enriched" "Detected in some" 18 "renal cancer: 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 4.6;SuSa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (8.45e-3)" "unprognostic (4.20e-1)" "unprognostic (5.44e-2)" "unprognostic (1.64e-5)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (1.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.21e-4)" "unprognostic (2.93e-1)" "unprognostic (1.25e-3)" "unprognostic (3.79e-2)" "unprognostic (2.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.91e-1)" 0.2 0.3 13.4 0.0 16.5 0.1 0.1 11.0 20.1 0.1 13.9 0.1 2.6 0.1 0.3 0.0 7.1 0.0 2.6 12.2 11.9 153.1 36.8 0.8 0.0 11.6 12.6 0.2 0.0 0.0 3.0 0.0 11.7 0.5 0.0 1.1 0.1 0.1 0.5 0.2 0.6 0.0 12.1 0.3 0.1 3.1 13.8 0.1 6.3 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.5 11.0 20.1 12.2 11.9 11.6 12.6 11.7 12.1 13.8 11.7 0.0 0.0 0.6 1.3 1.9 0.0 0.0 0.4 0.0 0.4 0.1 0.1 1.5 0.0 0.1 18.4 2.1 0.0 0.1 0.0 49.0 0.0 1.4 0.6 0.1 0.2 0.0 5.3 3.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 27.0 0.0 0.0 1.2 0.0 2.0 1.6 0.0 0.6 0.3 1.7 0.0 17.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.1 0.5 324.9 0.7 0.7 0.0 0.4 0.1 0.6 0.4 0.0 0.0 0.3 0.9 0.0 0.0 0.0 SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.9;pituitary gland: 7.3;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 28.4;Excitatory neurons: 61.9;Horizontal cells: 28.6;Inhibitory neurons: 90.2;Oligodendrocytes: 67.4" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.2;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" 0.0 2.3 8.9 0.4 8.1 0.1 0.0 5.5 8.8 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.9 15.9 0.1 0.0 0.0 0.0 15.6 6.4 0.1 0.7 0.0 7.3 0.0 14.9 0.1 0.4 6.1 0.0 0.0 0.1 0.1 0.3 0.1 4.0 0.0 0.2 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.1 0.0 0.5 0.9 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 8.1 5.5 8.8 7.9 15.9 15.6 6.4 14.9 4.0 8.9 7.7 0.8 3.2 2.2 4.6 0.1 0.4 0.3 0.1 0.0 28.4 0.1 0.0 1.0 0.0 2.5 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.5 1.8 0.0 61.9 0.0 0.1 0.4 0.0 0.1 2.5 0.1 0.4 0.9 0.0 28.6 90.2 0.1 0.0 0.0 1.2 0.6 2.1 0.4 3.6 6.5 0.0 1.8 0.0 9.5 67.4 0.1 1.2 2.6 0.1 0.3 0.1 0.2 3.0 4.3 0.0 0.7 0.5 0.0 0.2 0.0 0.6 0.0 0.4 0.1 0.0 0.2 SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.7;brain: 121.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 178.7;Microglial cells: 109.6;Plasma cells: 135.1;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1326.5;hTCEpi: 2229.0;MCF7: 1264.6;SiHa: 1873.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Vesicles "HPA052673: AB_2681909, HPA056077: AB_2683031" "unprognostic (2.71e-3)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (6.86e-2)" "unprognostic (4.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.93e-2)" "unprognostic (5.52e-3)" "unprognostic (1.64e-2)" "unprognostic (7.19e-3)" 10.6 3.9 121.9 18.3 87.8 110.7 6.0 89.5 119.4 11.0 64.5 11.4 6.6 5.2 35.7 100.2 6.4 6.6 21.1 96.0 91.0 18.0 26.6 9.8 14.1 111.3 104.3 8.1 14.0 1.8 22.8 17.0 104.9 9.8 2.7 42.5 28.6 10.4 30.1 25.1 8.9 3.2 93.0 16.7 34.4 65.6 117.1 6.9 3.9 2.8 11.5 24.6 22.6 88.1 187.4 693.5 13.2 192.1 5.1 10.6 487.3 147.1 52.8 87.4 56.3 456.3 260.4 170.1 126.7 187.6 30.5 818.3 142.5 1326.5 61.0 179.9 71.9 140.3 618.0 331.2 199.5 131.2 246.0 35.9 2229.0 107.8 791.4 28.5 18.0 588.8 212.6 185.1 71.1 1264.6 159.2 192.7 63.3 116.7 166.0 152.0 52.4 264.1 98.3 15.7 109.2 43.5 1873.1 368.9 406.9 123.0 170.0 171.8 14.3 30.9 201.3 127.8 114.5 237.9 213.2 728.2 120.1 322.1 296.4 1.0 0.0 0.0 1.0 0.0 1.3 0.5 0.5 0.9 0.4 0.0 0.1 0.4 0.2 0.2 0.0 17.2 1.6 0.5 121.9 87.8 89.5 119.4 96.0 91.0 111.3 104.3 104.9 93.0 117.1 88.1 3.7 0.0 0.6 8.1 23.0 73.3 17.9 27.0 178.7 15.2 12.0 8.9 2.9 2.8 6.3 1.8 16.7 15.4 80.0 3.4 0.0 18.1 1.0 20.5 7.6 29.1 86.3 86.3 12.0 9.6 35.4 9.5 43.3 51.0 66.9 4.5 1.8 17.3 9.2 10.1 13.2 6.3 8.2 3.0 50.5 5.0 1.8 51.0 39.2 109.6 2.6 14.8 2.1 15.1 1.6 25.7 2.3 1.5 135.1 18.2 1.0 0.4 3.2 52.7 0.0 33.6 31.5 1.6 4.5 58.8 37.5 107.4 65.8 2.7 4.2 42.8 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 41.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.7;Early spermatids: 21.6;NK-cells: 26.8;Proximal tubular cells: 32.8" "Cancer enriched" "Detected in many" 5 "renal cancer: 22.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cell line enhanced" "Detected in some" "Karpas-707: 17.5;RPTEC TERT1: 98.8;U-937: 25.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (1.63e-2)" "unprognostic (2.47e-2)" "unprognostic (4.48e-4)" "unprognostic (5.70e-6)" "unprognostic (7.43e-2)" "unprognostic (7.71e-3)" "unprognostic (3.24e-3)" "unprognostic (2.05e-3)" "unprognostic (2.13e-1)" "unprognostic (7.12e-2)" "unprognostic (3.87e-3)" "unprognostic (5.83e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.29e-2)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" "unprognostic (8.22e-2)" 0.4 0.8 0.2 0.6 0.3 8.6 0.5 0.0 0.4 0.3 0.0 1.0 2.2 0.1 0.2 0.1 0.2 2.3 0.3 0.2 0.0 41.6 7.6 7.8 0.5 0.2 0.0 0.1 0.4 0.1 0.2 0.1 0.2 0.0 0.8 0.1 2.0 3.6 0.1 0.3 1.5 0.1 0.0 1.3 0.6 0.8 0.3 1.0 1.6 0.1 0.2 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 1.1 0.0 1.0 0.2 1.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 17.5 0.0 1.3 0.1 0.3 0.8 0.0 0.0 0.0 0.0 1.2 98.8 0.1 0.7 0.5 0.0 0.3 0.0 2.3 0.0 2.4 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 25.8 0.1 9.5 1.0 7.3 3.8 0.0 0.3 0.0 0.6 2.1 0.4 0.1 0.2 1.3 9.8 2.6 0.0 0.2 0.0 1.0 0.2 0.3 0.0 0.4 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.3 0.1 6.4 49.7 0.3 0.6 0.0 0.1 1.2 0.0 0.0 1.8 0.3 0.3 1.5 6.4 5.5 0.0 0.0 9.6 1.4 1.9 0.2 21.6 0.0 0.1 0.3 0.0 5.7 9.1 0.8 0.0 0.3 0.0 1.6 5.7 0.0 0.4 11.0 0.2 0.0 6.6 0.1 2.0 0.6 0.3 2.6 0.3 2.4 0.0 1.0 3.2 0.0 26.8 1.5 0.3 0.3 0.1 0.0 1.4 0.0 1.8 32.8 3.1 0.0 0.0 0.1 0.1 2.5 2.4 0.0 0.0 0.0 3.4 0.1 1.1 0.4 SLX4 "BTBD12, FANCP, KIAA1784, KIAA1987" ENSG00000188827 "SLX4 structure-specific endonuclease subunit" Q8IY92 16 3581181-3611606 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049421, HPA066238" Approved Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "HPA049421: AB_2680759, HPA066238: AB_2685642" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-2)" "unprognostic (4.62e-1)" "unprognostic (6.08e-3)" "unprognostic (8.28e-5)" "unprognostic (6.52e-2)" "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-2)" "unprognostic (1.50e-1)" "unprognostic (4.32e-2)" "unprognostic (8.39e-3)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (5.74e-2)" 1.8 2.1 2.1 2.9 1.9 3.0 1.6 7.1 2.7 2.1 0.4 2.3 2.2 2.1 1.3 2.4 2.0 1.1 1.9 2.3 2.1 1.9 1.9 2.1 4.1 2.3 2.0 1.6 1.7 1.1 3.9 1.1 1.8 2.3 0.9 1.7 1.6 1.0 2.7 1.8 2.8 1.2 1.1 3.4 2.2 10.6 1.9 2.7 1.8 1.3 2.9 2.1 2.0 2.1 2.7 8.4 5.3 6.7 2.0 2.1 5.6 4.3 2.2 4.9 5.4 4.2 3.3 10.0 4.2 2.2 3.8 6.0 3.6 3.0 2.9 8.4 4.6 6.8 6.5 2.7 1.8 6.7 9.3 1.5 2.2 4.6 2.6 1.2 3.6 5.6 6.7 5.3 3.9 4.7 4.2 5.9 4.5 1.7 3.1 8.2 8.9 2.8 1.9 1.9 4.5 4.1 3.8 2.6 1.3 2.8 6.5 5.2 4.3 5.6 7.8 4.9 5.1 4.8 4.0 11.4 1.8 6.7 5.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 2.1 1.9 7.1 2.7 2.3 2.1 2.3 2.0 1.8 1.1 1.9 2.1 2.7 0.0 2.3 4.6 4.5 0.8 0.8 1.1 4.0 8.7 2.0 1.4 1.7 1.5 3.2 0.0 2.1 1.7 3.4 2.0 0.0 1.5 6.5 5.5 4.2 1.8 0.0 6.5 9.5 2.4 1.6 2.4 3.6 4.6 0.0 4.8 1.1 1.4 2.9 0.0 9.3 2.4 2.0 2.9 1.6 2.3 2.1 5.1 0.0 4.7 2.2 2.7 4.1 7.1 5.5 2.0 0.3 1.9 4.0 0.4 2.3 0.6 2.3 10.1 0.0 4.9 2.5 20.0 9.1 2.3 0.6 1.0 4.4 3.0 2.1 0.6 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: AB_2685803" "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 48.6 52.6 38.0 38.6 42.4 37.5 46.5 46.2 36.7 43.2 35.6 47.5 36.7 38.6 41.0 55.0 46.8 39.6 53.8 32.9 48.6 43.3 35.6 46.7 44.5 50.2 43.2 52.5 40.4 44.6 20.3 42.7 51.9 36.4 48.7 70.5 36.7 44.8 57.4 34.0 37.4 47.9 47.8 47.5 45.2 51.5 42.4 72.4 75.7 55.5 55.2 53.8 31.1 59.4 81.1 113.7 68.0 66.2 106.1 128.5 77.4 86.1 102.7 87.9 101.8 43.8 75.6 124.8 60.3 110.0 123.0 86.6 77.2 96.1 116.9 136.4 39.3 106.4 164.4 71.9 123.2 149.6 104.1 95.8 121.4 75.5 172.9 102.1 98.6 99.7 50.3 101.6 109.6 52.7 103.4 71.6 33.6 4.4 26.7 74.4 98.9 85.9 197.8 137.2 62.8 73.3 103.7 70.1 85.7 65.8 53.5 97.7 111.4 129.5 74.2 35.6 63.6 99.0 102.7 108.3 89.6 99.9 97.1 58.8 33.6 38.7 23.8 38.5 29.8 16.7 32.3 29.9 32.8 13.9 35.3 27.6 34.1 38.6 33.0 23.3 40.5 31.6 38.0 42.4 46.2 36.7 32.9 48.6 50.2 43.2 51.9 47.8 42.4 59.4 55.0 44.8 36.1 55.8 36.3 54.4 44.1 38.3 54.1 48.0 44.2 30.2 49.2 41.5 45.5 77.3 212.7 48.2 53.0 42.8 39.2 36.5 68.1 58.6 53.0 53.1 51.0 36.4 63.4 43.5 40.3 40.5 44.4 68.1 21.5 80.0 56.4 29.6 43.9 35.3 50.5 46.1 38.7 57.3 41.8 131.9 41.7 48.7 51.6 104.9 63.9 44.8 72.1 96.0 130.0 44.0 31.6 53.4 34.5 66.1 37.9 39.5 41.8 88.1 32.9 53.5 39.6 37.2 39.4 59.2 61.8 69.5 47.4 41.7 42.3 77.2 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 SMAD6 "HsT17432, MADH6, MADH7" ENSG00000137834 "SMAD family member 6" O43541 15 66702236-66782849 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.1;lung: 27.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 25.1;Hepatic stellate cells: 91.4;Microglial cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 29.8;HaCaT: 18.2;HeLa: 28.6;U-2197: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061917 Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA061917: AB_2684637" "unprognostic (1.20e-1)" "unprognostic (7.43e-3)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.02e-1)" "unprognostic (3.50e-3)" "unprognostic (9.59e-2)" "unprognostic (4.50e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.10e-3)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (1.55e-3)" "unprognostic (4.30e-2)" "unprognostic (1.33e-1)" "prognostic favorable (5.45e-5)" 9.5 2.6 5.2 1.6 4.9 0.1 7.6 4.9 4.3 6.8 8.6 3.7 1.9 6.2 0.6 2.1 5.4 1.4 30.1 3.4 4.1 8.9 6.7 27.9 0.5 7.6 5.4 5.9 2.7 1.1 3.4 7.4 5.8 7.0 1.1 0.9 2.1 3.5 1.6 2.4 3.9 0.9 4.4 2.6 5.5 1.8 6.8 0.4 15.5 1.5 0.2 8.0 5.7 4.6 1.3 10.2 1.6 3.5 6.0 1.6 9.4 7.2 0.1 1.1 0.1 2.0 4.6 0.7 29.8 6.1 0.9 18.2 2.2 0.0 0.2 2.3 8.4 16.1 28.6 1.7 0.7 0.1 1.2 2.0 0.0 0.1 0.0 3.4 1.3 5.1 1.4 1.0 0.5 2.0 0.1 4.4 3.0 10.5 3.8 0.0 1.8 2.2 3.4 8.1 3.6 1.6 3.9 4.3 0.8 5.9 1.4 2.9 6.2 4.3 5.5 17.6 1.4 0.5 1.8 0.3 3.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 4.9 4.9 4.3 3.4 4.1 7.6 5.4 5.8 4.4 6.8 4.6 19.8 12.8 6.0 5.2 0.9 0.8 1.2 2.1 0.6 0.6 0.9 1.1 4.9 4.3 3.0 1.8 2.1 0.8 0.1 4.3 3.9 4.7 3.4 8.3 5.5 25.1 0.0 0.0 0.3 5.8 0.9 4.9 5.1 6.5 4.5 5.9 91.4 4.0 1.7 0.0 0.3 2.1 0.0 10.0 0.3 1.4 2.8 1.2 0.0 57.1 0.7 10.2 0.0 0.5 0.4 8.4 1.5 8.2 0.0 1.3 2.1 1.9 0.1 0.6 0.0 0.9 1.5 0.2 3.2 0.4 0.1 0.8 0.4 0.1 5.5 0.4 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SMAP1 "FLJ13159, SMAP-1" ENSG00000112305 "Small ArfGAP 1" Q8IYB5 6 70667776-70862011 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 325.7;Late spermatids: 281.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030574 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA030574: AB_10601589" "unprognostic (1.55e-1)" "unprognostic (2.66e-3)" "unprognostic (1.01e-3)" "unprognostic (2.98e-3)" "unprognostic (7.06e-2)" "unprognostic (2.90e-2)" "unprognostic (1.66e-3)" "unprognostic (3.46e-1)" "unprognostic (6.50e-2)" "unprognostic (3.75e-2)" "unprognostic (7.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.32e-1)" "unprognostic (4.73e-2)" "unprognostic (6.08e-2)" "unprognostic (2.85e-1)" "unprognostic (1.22e-1)" 17.0 12.8 24.4 16.1 27.8 18.6 13.6 19.5 44.8 15.2 13.3 27.5 26.8 14.1 18.0 28.4 10.2 17.4 23.1 27.6 24.3 14.1 16.6 14.9 15.4 22.7 25.3 11.1 37.2 28.5 8.6 16.1 23.7 17.6 28.3 24.8 18.0 15.2 32.9 20.4 26.7 19.7 20.1 13.7 20.9 30.9 24.4 24.8 21.1 20.1 22.4 18.1 16.1 29.2 60.3 18.6 28.5 35.3 26.0 33.9 46.4 26.6 29.5 21.4 20.9 27.9 17.4 31.4 28.1 32.0 30.5 18.5 27.4 28.1 35.5 36.3 39.4 34.7 16.5 23.6 17.2 25.5 28.0 22.3 31.3 24.2 29.2 39.6 34.2 16.1 33.8 36.9 33.8 35.0 19.2 31.4 21.3 30.9 21.9 36.0 107.9 51.8 38.1 36.0 40.7 28.7 16.9 23.3 17.1 24.2 31.0 37.3 33.6 17.2 29.7 11.4 23.5 34.3 32.9 16.0 13.0 29.4 24.2 35.0 16.4 18.4 18.2 18.3 20.7 14.8 24.3 21.0 14.0 12.7 12.1 15.7 22.6 25.6 20.0 13.7 25.3 23.4 24.4 27.8 19.5 44.8 27.6 24.3 22.7 25.3 23.7 20.1 24.4 29.2 45.0 38.5 39.4 58.1 39.3 66.9 37.7 66.9 33.0 51.8 39.6 47.2 38.8 52.9 46.0 38.6 37.5 26.2 47.6 111.3 54.8 78.9 325.7 26.1 46.8 43.2 41.9 28.8 120.1 151.0 48.8 40.3 64.7 52.1 48.2 42.9 58.5 41.3 56.6 55.5 104.3 82.3 61.1 61.2 59.8 281.1 50.7 53.0 32.0 60.0 64.1 69.7 64.9 115.6 72.7 108.2 99.5 67.0 51.8 76.3 92.6 69.6 21.1 38.6 65.7 36.3 53.3 105.2 84.2 89.3 77.3 31.7 64.9 44.1 75.8 51.6 SMARCA2 "BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2" ENSG00000080503 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" P51531 9 1980290-2193624 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Disease variant, Hypotrichosis, Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 246.5;Inhibitory neurons: 263.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "HDLM-2: 1486.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029981, CAB037276" Enhanced Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA 19000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB037276: AB_477083, HPA029981: AB_10602406" "unprognostic (5.34e-2)" "unprognostic (1.99e-2)" "unprognostic (6.27e-2)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (3.60e-3)" "unprognostic (9.64e-2)" "prognostic favorable (1.26e-6)" "unprognostic (3.09e-1)" "unprognostic (2.81e-1)" "unprognostic (8.32e-3)" "unprognostic (8.50e-2)" 51.9 55.9 68.9 36.1 73.9 95.7 62.0 87.4 81.7 42.1 40.2 31.0 20.2 53.2 57.3 41.7 57.4 46.0 43.8 60.3 53.7 45.9 58.3 40.3 50.9 43.2 54.4 166.0 36.8 170.3 32.7 48.2 50.6 42.5 31.7 63.6 50.7 53.2 97.7 48.2 27.7 44.2 40.3 52.3 32.0 56.3 55.7 42.2 55.7 60.1 47.8 31.8 28.8 52.9 45.7 32.9 23.7 33.8 47.2 56.6 71.7 59.4 44.6 24.9 19.5 0.5 17.7 76.2 22.0 50.7 13.5 18.8 12.9 46.5 17.6 1486.7 20.2 208.3 88.2 16.2 18.7 88.3 118.1 37.6 17.5 24.9 46.4 44.9 40.3 35.4 7.3 255.1 43.0 19.1 22.2 72.3 23.4 26.4 12.6 97.6 30.5 69.4 57.6 40.9 15.3 14.0 36.2 8.3 14.9 34.1 16.3 55.8 49.1 40.6 19.8 25.8 27.3 22.9 31.8 33.6 43.5 32.5 11.4 26.1 5.2 15.8 10.8 7.2 10.4 12.3 10.5 11.2 6.4 9.4 13.1 10.3 14.6 9.9 10.3 12.5 12.6 5.0 68.9 73.9 87.4 81.7 60.3 53.7 43.2 54.4 50.6 40.3 55.7 52.9 83.9 73.7 70.6 246.5 57.2 58.6 18.3 55.0 82.6 57.6 103.7 74.3 95.2 31.5 54.1 106.7 37.5 99.3 102.8 32.0 31.3 30.6 38.0 44.1 61.6 69.0 37.2 41.2 216.2 22.4 24.5 65.7 19.4 45.2 48.0 27.9 36.8 62.0 31.5 35.3 263.2 31.2 48.8 54.9 34.7 22.6 76.7 57.5 49.8 142.4 45.2 53.4 43.3 120.6 100.8 18.7 15.1 86.9 71.4 13.9 26.9 18.5 88.3 37.4 13.1 58.7 40.3 42.9 14.6 66.2 52.7 88.7 74.8 56.1 28.2 12.7 SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960932-11079426 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 372.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004208, HPA048340" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nucleoli fibrillar center, Nucleoli rim" "CAB004208: AB_626762, HPA048340: " "unprognostic (2.68e-1)" "unprognostic (4.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.43e-3)" "unprognostic (1.40e-1)" "unprognostic (6.33e-3)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-2)" "unprognostic (6.80e-3)" "unprognostic (6.83e-3)" "unprognostic (5.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.8 16.2 14.4 22.6 14.3 31.8 13.0 15.3 23.7 16.1 13.2 18.1 19.9 14.5 9.5 32.9 20.8 13.3 16.2 15.4 9.6 15.7 8.6 17.9 27.0 10.4 10.4 14.9 18.3 22.9 11.1 20.2 11.0 17.7 12.9 19.7 25.9 15.6 23.7 28.1 17.2 14.5 3.9 19.5 20.4 30.2 11.8 43.1 20.6 13.9 23.7 17.4 14.7 19.3 92.5 5.0 157.2 149.8 30.3 25.4 68.9 62.7 37.2 74.6 54.9 126.9 4.0 215.4 94.2 54.9 3.0 65.9 123.6 77.5 40.8 89.5 93.3 171.3 76.5 149.6 45.7 125.5 82.0 43.1 36.7 63.1 64.5 33.3 67.5 92.0 156.7 78.3 59.2 188.0 210.0 107.5 159.9 45.1 134.7 220.6 99.5 111.7 47.9 114.8 177.8 161.7 66.6 84.4 73.5 50.1 71.9 93.3 90.9 110.3 57.3 102.5 104.9 160.6 192.2 209.1 62.6 118.5 96.0 5.7 5.8 6.4 9.3 6.9 8.2 5.3 6.8 7.9 6.1 6.8 7.6 7.5 3.4 8.5 10.8 7.9 6.4 4.7 14.4 14.3 15.3 23.7 15.4 9.6 10.4 10.4 11.0 3.9 11.8 19.3 25.4 67.3 72.6 27.4 28.5 37.0 43.7 43.8 24.5 91.3 42.2 28.4 372.9 40.0 62.7 44.1 70.9 65.9 21.2 60.1 41.1 79.8 53.0 58.8 49.2 58.3 63.2 41.8 32.2 61.4 57.3 43.8 50.0 63.5 30.4 75.3 28.5 21.9 42.3 101.0 39.6 47.7 57.0 23.8 21.5 37.6 26.1 30.4 16.0 14.0 43.8 36.1 23.7 32.6 28.1 76.4 41.8 13.5 37.6 66.0 29.8 27.6 62.5 69.1 13.1 45.1 66.4 99.4 86.0 52.2 51.7 61.0 30.4 68.1 60.5 50.1 SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 103.2;Late spermatids: 329.5;Syncytiotrophoblasts: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096" Uncertain Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "HPA041763: AB_2677659, HPA042096: AB_2677845" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-2)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.71e-1)" "unprognostic (4.11e-2)" "unprognostic (9.24e-3)" "unprognostic (3.88e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.09e-4)" 9.0 11.7 10.3 10.9 10.8 8.4 8.7 10.9 13.5 10.6 5.9 9.0 8.0 9.0 7.7 9.2 7.7 6.8 7.7 10.2 10.6 7.7 6.6 10.0 13.0 13.1 11.6 7.8 5.8 8.8 9.4 10.1 13.6 11.5 6.2 5.9 12.0 6.9 7.5 10.7 10.0 8.1 9.5 13.5 8.7 33.8 11.6 11.8 8.3 7.1 12.0 10.0 9.9 14.9 25.3 27.2 19.5 12.5 13.4 18.9 13.1 35.1 20.8 38.4 28.7 19.4 32.5 27.4 16.9 24.1 13.2 10.7 22.9 19.7 24.9 21.1 13.2 49.2 20.5 12.9 15.6 37.4 25.9 10.1 16.6 27.9 29.6 32.1 15.8 25.0 37.7 23.6 18.0 17.9 39.9 10.6 9.4 48.0 18.2 21.2 16.1 12.3 20.4 20.4 32.4 15.9 36.7 27.4 21.3 15.4 16.6 20.5 19.2 59.7 35.4 22.3 27.1 11.5 26.8 33.4 17.9 28.4 49.7 1.0 5.3 3.3 5.1 7.7 4.5 7.4 5.1 4.3 6.9 5.3 6.7 4.5 1.3 4.2 11.7 6.1 4.1 11.3 10.3 10.8 10.9 13.5 10.2 10.6 13.1 11.6 13.6 9.5 11.6 14.9 7.7 32.1 8.3 20.9 13.7 9.3 15.0 16.8 11.4 13.2 10.0 11.0 4.4 4.3 9.0 9.2 4.2 49.5 11.3 9.5 1.9 12.2 103.2 5.5 7.0 12.0 4.2 7.8 19.5 8.7 15.8 11.4 15.8 8.9 9.5 12.1 11.0 3.3 21.4 13.5 23.0 11.3 8.2 10.3 9.2 329.5 13.1 12.1 10.6 11.2 16.2 6.0 4.1 16.1 29.6 13.6 9.2 12.0 11.2 15.9 8.5 6.8 8.4 9.2 6.6 11.2 8.5 42.6 16.2 8.4 7.1 95.4 9.3 11.8 12.2 11.1 SMIM13 C6orf228 ENSG00000224531 "Small integral membrane protein 13" P0DJ93 6 11093834-11138733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 75.1;Syncytiotrophoblasts: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065706 Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear membrane, Golgi apparatus" "HPA065706: AB_2685539" "unprognostic (6.89e-2)" "unprognostic (1.22e-1)" "unprognostic (1.58e-1)" "unprognostic (7.11e-3)" "unprognostic (4.01e-1)" "unprognostic (2.57e-1)" "unprognostic (3.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (6.66e-2)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.04e-2)" "unprognostic (2.76e-1)" "unprognostic (9.22e-2)" "unprognostic (3.45e-2)" 4.7 4.6 15.4 3.4 16.1 2.9 3.4 21.4 23.8 4.3 5.6 4.1 3.6 5.0 3.4 4.8 2.9 4.1 6.6 16.7 18.0 4.3 9.7 3.5 3.0 17.6 16.7 4.1 3.0 6.4 4.1 12.7 19.3 4.6 3.6 17.1 3.7 4.8 11.5 4.9 3.1 5.2 15.8 2.9 3.1 3.4 20.0 3.4 3.0 14.2 3.0 4.9 3.7 19.4 9.9 8.3 12.6 10.6 12.7 14.4 13.2 26.7 11.3 13.4 14.9 11.1 3.1 12.1 35.9 8.6 13.3 8.6 26.3 9.3 24.0 7.1 19.1 12.7 9.1 8.8 16.9 23.8 2.9 17.4 25.5 13.7 18.0 10.6 14.4 11.0 18.3 5.0 25.7 5.4 10.1 14.0 5.9 6.5 7.1 13.5 23.1 17.2 8.2 7.6 29.4 16.3 5.6 18.2 32.4 17.2 4.6 9.9 20.7 20.3 15.0 8.6 18.1 9.5 33.0 17.1 4.8 9.9 31.8 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 15.4 16.1 21.4 23.8 16.7 18.0 17.6 16.7 19.3 15.8 20.0 19.4 14.3 12.8 1.5 12.4 9.1 75.1 17.1 13.7 10.8 16.4 10.6 10.3 12.7 12.8 5.2 11.0 20.9 29.3 14.4 5.7 3.9 5.2 10.3 11.8 15.6 11.4 3.6 11.8 26.8 7.4 36.6 11.9 6.1 12.0 10.8 4.2 7.9 25.6 13.5 30.3 31.4 8.1 10.2 8.1 29.4 4.3 2.8 12.0 16.0 10.3 6.3 7.6 7.2 18.6 28.0 10.5 3.1 4.1 14.6 18.8 5.8 7.8 4.6 15.2 0.0 7.7 9.8 16.8 24.8 12.7 39.5 65.1 12.9 10.4 8.7 16.2 SMIM20 "C4orf52, MITRAC7, PNX" ENSG00000250317 "Small integral membrane protein 20" Q8N5G0 4 25861830-25929874 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016552 Approved Approved Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA016552: AB_1859536" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" "unprognostic (1.78e-1)" "unprognostic (6.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.02e-1)" "unprognostic (5.42e-2)" "unprognostic (2.86e-1)" "prognostic favorable (8.97e-5)" "unprognostic (5.51e-2)" "unprognostic (5.84e-2)" "unprognostic (1.53e-1)" "unprognostic (5.12e-3)" 27.9 36.7 36.7 16.6 37.7 13.1 27.2 38.1 50.2 22.2 39.8 30.9 39.9 23.9 72.2 15.7 23.8 23.9 46.8 36.5 38.4 46.0 38.2 19.7 30.4 36.9 36.1 33.9 43.4 28.2 17.6 14.1 36.9 23.9 25.5 29.9 35.1 17.5 95.9 13.9 35.1 17.8 37.9 23.6 38.6 20.5 36.8 17.4 31.4 61.4 24.8 28.8 19.1 39.2 29.9 24.5 32.3 31.3 34.9 75.4 43.0 28.4 34.3 24.0 30.4 21.9 51.6 48.8 48.1 31.7 49.6 8.5 37.9 36.3 33.4 27.9 30.1 28.3 16.4 42.0 59.1 34.0 18.0 53.9 71.6 30.6 46.1 46.7 18.7 32.5 45.9 15.5 29.6 19.1 37.0 57.5 61.0 39.6 36.1 30.1 42.0 31.7 53.5 21.6 41.3 38.4 18.3 12.7 66.0 35.2 26.3 47.5 31.4 25.8 30.5 29.3 36.8 30.2 26.9 52.6 39.2 35.6 33.4 30.6 31.5 15.9 26.2 37.7 34.5 47.3 37.5 33.2 36.9 47.9 50.4 41.1 16.3 35.6 29.4 38.3 42.9 31.7 36.7 37.7 38.1 50.2 36.5 38.4 36.9 36.1 36.9 37.9 36.8 39.2 21.5 9.6 41.6 9.4 48.0 21.9 30.4 89.4 26.7 7.7 49.8 63.1 61.8 61.5 59.0 36.8 8.4 63.7 22.5 50.9 131.0 70.0 11.5 34.7 30.6 23.1 19.3 9.2 3.8 62.5 59.7 40.0 31.6 34.6 10.8 37.1 21.8 66.5 69.7 1.7 4.6 64.0 59.0 62.9 32.1 23.1 37.6 44.5 44.4 4.7 42.9 95.3 38.1 9.5 7.9 46.2 44.6 48.2 38.4 38.9 130.1 166.5 47.0 22.2 72.3 26.8 35.8 44.5 36.4 27.3 19.5 43.8 29.8 71.2 65.4 30.8 SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.3" "Cell type enhanced" "Detected in many" "Ductal cells: 48.4;Erythroid cells: 89.7;Macrophages: 73.3;Pancreatic endocrine cells: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0" "Cell line enhanced" "Detected in many" "A549: 119.6;Karpas-707: 201.7;RPTEC TERT1: 91.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Vesicles, Cytosol" "HPA047117: AB_2679940, HPA060198: AB_2684220" "unprognostic (1.24e-2)" "unprognostic (6.55e-2)" "unprognostic (7.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.33e-6)" "prognostic unfavorable (1.36e-4)" "unprognostic (4.92e-2)" "unprognostic (3.37e-1)" "unprognostic (7.18e-2)" "unprognostic (7.58e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (4.08e-2)" "unprognostic (2.64e-3)" "unprognostic (1.26e-2)" "unprognostic (3.07e-1)" 8.5 4.4 50.9 4.4 61.3 32.2 5.3 54.5 60.9 17.7 32.8 5.6 10.6 10.8 7.1 8.5 7.4 15.1 6.8 46.3 51.7 20.5 8.5 4.9 4.8 56.6 54.4 12.5 32.5 25.2 13.2 6.2 53.7 12.2 1.2 2.9 12.1 7.9 4.3 11.9 8.1 4.0 53.0 6.4 20.1 5.8 55.5 4.3 6.8 2.8 2.6 8.2 12.4 54.1 11.0 119.6 8.3 6.3 5.5 8.2 14.6 15.6 29.8 11.1 7.4 49.5 29.6 0.0 5.1 14.4 18.0 21.6 6.8 7.5 4.8 0.0 3.5 21.5 4.1 50.6 35.0 4.1 8.3 31.3 13.1 23.1 9.8 13.4 19.8 16.7 4.8 201.7 6.7 3.3 8.1 12.1 10.2 10.7 16.3 7.3 10.3 29.1 91.4 8.3 1.6 7.2 28.9 3.4 54.1 4.2 0.3 5.1 24.0 12.7 12.0 2.3 12.2 9.1 1.7 0.1 10.6 5.4 9.8 0.0 1.0 0.2 0.0 0.4 0.0 0.1 0.2 0.2 2.4 0.0 0.0 0.0 3.6 0.3 0.1 1.1 0.0 16.0 50.9 61.3 54.5 60.9 46.3 51.7 56.6 54.4 53.7 53.0 55.5 54.1 4.4 0.0 0.5 38.5 3.8 12.6 12.0 14.4 6.8 0.5 6.9 4.6 1.7 12.8 6.3 11.0 0.0 0.4 0.2 1.4 0.0 48.4 4.0 9.2 15.8 11.2 6.0 89.7 1.6 30.5 0.8 11.3 6.6 18.7 5.7 10.4 13.6 2.3 20.6 0.0 3.5 3.0 6.1 3.1 10.2 7.7 14.6 73.3 8.8 5.6 22.6 25.4 1.0 9.0 6.2 131.3 1.5 13.5 7.4 13.1 4.0 3.8 1.2 1.4 0.0 2.7 10.2 19.1 7.8 2.1 10.5 0.3 2.1 1.9 3.7 12.6 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440724-109443919 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Early spermatids: 179.4;Late spermatids: 359.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favorable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favorable (1.70e-4)" 6.9 8.8 7.6 8.6 7.4 12.7 10.5 9.6 7.8 12.6 15.1 12.7 13.5 7.1 15.5 24.5 21.4 8.7 6.7 7.7 6.9 12.2 7.6 9.7 13.3 7.6 7.9 8.2 17.7 22.1 11.1 6.0 7.2 13.2 12.6 6.5 15.6 5.8 4.1 21.7 12.3 4.9 7.6 13.3 14.2 53.0 7.0 10.3 13.3 1.7 17.1 10.4 14.3 8.8 13.1 14.8 7.7 12.2 13.2 7.1 25.5 4.3 15.7 10.5 9.8 14.0 10.3 7.1 9.0 9.3 22.1 16.4 7.8 18.7 6.3 9.1 20.5 8.2 15.9 8.7 11.0 9.1 9.4 7.7 21.3 9.3 18.4 11.8 9.8 12.4 16.3 12.2 5.3 18.7 14.8 19.7 2.1 17.3 7.5 10.4 3.6 7.7 19.3 21.8 10.1 8.4 8.2 24.9 19.3 6.2 7.9 17.2 6.3 4.7 6.8 3.8 16.3 8.3 2.3 4.6 9.1 8.6 8.5 6.2 9.0 10.8 6.9 8.6 7.8 14.4 7.8 8.2 11.2 20.4 5.6 5.9 2.5 7.3 7.8 14.3 8.2 6.0 7.6 7.4 9.6 7.8 7.7 6.9 7.6 7.9 7.2 7.6 7.0 8.8 3.9 12.8 7.2 1.6 15.9 9.8 12.9 13.8 8.6 1.3 8.9 6.7 2.1 7.2 11.8 12.9 4.2 10.3 9.1 26.1 1.9 19.2 179.4 28.4 4.0 4.4 8.4 4.2 1.4 19.8 18.5 6.1 25.0 4.3 0.0 3.5 3.6 3.6 9.5 0.0 0.5 27.1 14.2 4.1 11.2 359.7 9.3 7.2 8.8 2.8 9.9 3.7 6.2 0.0 1.7 15.4 27.7 9.1 9.8 15.0 37.5 9.3 67.1 4.9 13.1 3.1 5.8 69.9 10.9 13.8 18.6 17.0 7.6 8.7 17.8 16.9 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMUG1 "FDG, HMUDG, UNG3" ENSG00000123415 "Single-strand-selective monofunctional uracil-DNA glycosylase 1" Q53HV7 12 54121277-54189008 "Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 98.9;Syncytiotrophoblasts: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026804, HPA065892" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA026804: , HPA065892: " "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.58e-2)" "unprognostic (7.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.30e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.82e-1)" "unprognostic (6.12e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.67e-3)" "unprognostic (3.35e-1)" "unprognostic (2.41e-3)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.46e-1)" "unprognostic (1.73e-1)" 20.5 29.2 21.9 13.9 22.4 10.7 26.3 20.7 24.2 17.3 22.6 20.8 17.1 17.1 39.9 38.6 24.5 16.9 19.4 22.3 21.1 28.9 49.6 14.7 18.9 23.7 21.4 18.8 30.0 23.9 16.9 19.1 22.1 24.0 18.7 14.3 29.7 18.1 27.4 29.4 21.3 16.3 22.1 21.8 32.2 15.9 22.7 17.8 21.9 21.8 18.6 20.3 20.1 24.8 31.9 57.5 22.2 23.2 40.4 31.3 37.7 24.2 31.4 37.2 33.8 58.0 69.5 19.0 60.4 35.1 34.8 40.3 15.7 63.7 23.5 19.7 33.3 28.6 47.4 42.3 48.2 19.3 34.0 35.7 97.7 43.9 43.2 40.4 30.2 33.3 48.2 40.3 41.4 60.8 24.3 37.2 27.7 54.3 51.7 17.5 22.6 34.3 46.6 46.2 33.1 39.2 27.6 47.3 43.5 44.9 73.7 35.9 14.3 24.7 27.5 22.5 28.1 37.3 32.1 13.1 35.8 15.0 38.4 89.6 46.2 57.1 28.5 39.5 28.4 49.7 27.3 30.7 40.3 36.6 24.6 24.6 45.5 27.1 31.5 45.5 41.0 33.9 21.9 22.4 20.7 24.2 22.3 21.1 23.7 21.4 22.1 22.1 22.7 24.8 6.6 6.4 16.0 2.9 13.3 7.5 14.4 40.2 11.4 10.5 25.5 22.5 17.7 22.8 26.4 25.8 8.4 87.5 8.8 28.4 60.7 37.1 5.2 15.3 8.9 11.0 11.5 7.4 6.8 40.2 98.9 13.6 16.3 11.0 2.5 10.1 18.2 49.4 46.1 6.7 6.1 25.8 32.6 19.2 5.8 11.8 18.6 14.0 5.4 3.7 34.0 16.3 19.6 5.0 8.1 41.4 24.6 17.7 12.6 20.7 58.4 56.6 27.1 11.9 32.9 8.5 13.8 26.2 28.0 20.8 10.4 100.0 9.5 19.4 23.7 19.6 SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: AB_2191728" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (2.47e-1)" "unprognostic (4.23e-2)" "unprognostic (1.13e-2)" "unprognostic (3.66e-2)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-3)" "unprognostic (9.26e-3)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "unprognostic (7.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" 7.4 6.6 4.1 6.0 3.6 3.4 7.3 8.0 4.5 7.9 3.7 7.5 7.0 6.5 5.0 3.9 7.3 3.6 7.0 3.5 3.5 3.7 4.9 5.6 6.8 3.7 3.2 9.5 6.7 3.6 6.6 4.7 4.0 6.5 4.8 7.6 7.3 5.6 13.7 6.6 7.4 5.9 2.2 6.3 4.9 5.8 4.3 6.2 5.7 10.2 6.5 7.2 6.2 5.6 7.4 13.7 13.5 9.6 9.0 6.1 15.7 11.9 6.7 12.3 12.5 22.0 6.2 19.7 7.8 4.8 8.3 14.2 12.9 7.7 15.3 5.7 13.1 7.2 15.9 6.0 4.5 7.4 6.8 4.4 6.8 12.7 11.1 6.3 6.2 16.6 7.6 7.5 9.7 4.6 13.6 5.3 6.2 8.7 6.6 16.7 6.9 5.0 4.9 8.8 5.5 7.6 11.0 4.5 11.1 10.9 6.7 4.5 5.9 12.0 6.1 10.0 10.4 5.2 7.5 7.1 6.8 6.4 11.9 12.0 2.4 2.3 5.1 3.0 4.3 4.0 3.0 3.3 1.5 2.7 3.4 5.0 1.3 3.1 2.4 4.5 3.5 2.1 4.1 3.6 8.0 4.5 3.5 3.5 3.7 3.2 4.0 2.2 4.3 5.6 22.9 6.4 27.8 6.5 12.9 5.0 9.3 11.9 14.8 19.3 6.9 8.4 6.3 14.3 14.0 7.3 33.3 9.7 16.5 6.9 1.9 5.7 20.2 3.7 8.9 10.9 3.6 9.7 11.7 3.3 10.9 14.2 4.1 3.5 7.6 14.7 17.2 6.7 12.9 26.9 12.1 5.2 12.2 23.3 9.2 5.9 27.1 17.4 5.4 13.1 16.4 7.9 43.3 4.5 7.1 4.2 2.0 24.8 10.1 7.2 23.3 2.9 17.8 19.9 46.0 43.6 23.9 12.6 14.8 5.1 6.7 8.1 12.1 6.1 6.4 3.5 SNAPC2 "PTFdelta, SNAP45" ENSG00000104976 "Small nuclear RNA activating complex polypeptide 2" Q13487 19 7920338-7923250 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049843, HPA077597" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA049843: AB_2680910, HPA077597: AB_2732354" "unprognostic (4.56e-3)" "unprognostic (1.89e-1)" "unprognostic (7.98e-3)" "unprognostic (8.11e-3)" "unprognostic (2.03e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (1.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-1)" "unprognostic (5.45e-2)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (3.22e-1)" "unprognostic (5.30e-2)" "unprognostic (9.78e-2)" 21.2 21.6 15.4 10.4 17.7 16.7 19.6 14.7 21.4 37.1 11.0 36.1 9.7 50.7 5.7 14.3 35.0 8.3 16.6 17.1 16.0 17.2 11.9 17.1 9.1 15.6 15.2 20.7 17.8 10.1 25.5 6.5 16.4 27.0 3.8 1.8 16.6 17.2 9.0 20.5 15.2 12.4 13.8 21.4 18.7 32.6 16.3 7.6 13.1 9.7 4.9 31.7 25.1 15.3 20.6 22.9 10.8 42.0 14.7 31.1 10.0 21.4 22.6 20.5 18.5 10.6 17.4 17.6 25.8 25.0 16.4 24.7 7.7 15.9 5.9 22.7 19.7 24.5 9.6 15.4 26.6 15.4 38.7 25.5 24.0 24.3 14.9 16.6 23.5 18.1 24.5 28.3 12.7 18.1 19.9 43.6 13.9 10.4 51.8 23.4 10.7 17.6 19.1 7.1 12.7 28.7 11.0 11.8 48.6 4.8 19.2 16.6 30.9 68.8 24.5 65.2 26.8 27.4 48.1 10.8 43.1 31.6 22.2 7.0 23.8 23.5 19.0 30.8 19.2 15.7 16.1 16.5 30.1 14.5 16.6 16.9 3.5 27.7 33.4 19.9 24.0 16.4 15.4 17.7 14.7 21.4 17.1 16.0 15.6 15.2 16.4 13.8 16.3 15.3 19.8 3.2 3.7 3.3 15.4 24.3 20.0 25.1 35.9 8.6 25.8 26.2 3.2 7.2 10.7 11.0 0.0 12.2 22.9 9.8 17.6 21.2 1.9 10.7 25.0 20.7 12.0 20.2 4.1 24.5 24.2 18.5 8.6 15.0 18.4 15.4 12.5 5.2 28.6 23.5 2.6 11.9 14.2 19.6 28.0 6.0 13.7 19.2 19.6 1.0 31.3 6.0 13.4 2.0 3.0 28.9 6.6 14.3 8.4 28.5 16.7 16.1 3.0 6.1 13.1 7.3 30.1 9.5 38.6 19.0 24.3 9.9 18.4 29.2 15.5 24.1 SNAPC3 "MGC132011, MGC33124, PTFbeta, SNAP50" ENSG00000164975 "Small nuclear RNA activating complex polypeptide 3" Q92966 9 15422704-15465953 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 121.7;Late spermatids: 270.7;Spermatocytes: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053145, HPA066031" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Nucleoli "HPA053145: AB_2682055, HPA066031: AB_2685600" "unprognostic (2.62e-1)" "unprognostic (4.26e-1)" "unprognostic (5.42e-3)" "unprognostic (2.09e-1)" "unprognostic (4.93e-3)" "unprognostic (6.08e-2)" "unprognostic (5.60e-3)" "unprognostic (4.15e-2)" "unprognostic (1.68e-2)" "unprognostic (1.67e-2)" "unprognostic (1.12e-2)" "unprognostic (2.64e-2)" "unprognostic (1.36e-3)" "unprognostic (3.07e-1)" "unprognostic (2.63e-1)" "unprognostic (4.38e-2)" "unprognostic (2.09e-2)" 4.1 6.6 5.5 4.0 5.2 1.7 3.8 10.4 7.6 6.5 4.9 5.8 4.2 5.9 5.4 5.5 5.1 3.8 7.0 7.7 5.5 4.6 3.4 4.3 4.4 5.4 5.5 7.1 4.3 4.9 5.1 6.2 6.2 4.8 5.1 11.3 4.5 3.7 7.9 5.0 5.3 4.5 4.5 4.9 4.8 5.5 6.4 3.5 4.4 6.2 3.9 5.1 5.9 8.0 4.7 5.9 12.3 4.7 9.6 10.0 7.2 7.2 3.1 4.2 4.9 2.8 2.0 3.3 2.7 4.6 5.9 2.8 6.6 3.4 5.1 15.5 7.7 11.9 13.4 4.0 4.8 2.7 8.9 6.5 6.6 2.9 3.3 17.7 7.8 7.7 3.4 5.3 9.7 1.4 3.2 8.5 3.9 3.5 15.4 6.6 1.5 1.8 7.3 2.8 13.1 9.2 2.5 2.2 1.7 10.7 5.3 5.5 6.5 7.0 2.7 3.0 9.3 6.9 9.0 4.2 4.4 3.5 3.3 4.9 14.2 7.8 7.6 24.6 7.6 15.2 7.6 7.0 11.2 16.5 10.9 10.5 1.7 7.8 32.2 9.2 12.2 8.9 5.5 5.2 10.4 7.6 7.7 5.5 5.4 5.5 6.2 4.5 6.4 8.0 13.8 19.2 11.9 31.6 21.1 9.6 14.1 18.1 8.6 19.7 9.7 6.9 39.5 7.2 16.8 20.2 31.3 12.4 14.5 21.3 13.7 17.6 121.7 15.2 14.8 18.7 15.0 19.4 56.0 9.2 17.3 15.3 11.2 14.7 17.2 22.2 20.3 14.8 16.1 35.3 63.9 15.7 38.7 25.0 10.7 270.7 33.8 16.3 19.6 26.2 21.5 13.8 18.6 46.8 46.3 12.4 27.9 30.5 18.0 9.8 36.4 28.4 23.9 19.0 13.1 11.6 32.0 113.3 27.1 9.1 11.9 9.7 13.4 34.6 17.7 11.7 SNAPC4 "FLJ13451, PTFalpha, SNAP190" ENSG00000165684 "Small nuclear RNA activating complex polypeptide 4" Q5SXM2 9 136375577-136400168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028939, HPA046627, HPA073243" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028939: , HPA046627: AB_10961152, HPA073243: AB_2686585" "unprognostic (3.34e-2)" "unprognostic (2.12e-1)" "unprognostic (5.26e-2)" "unprognostic (1.75e-2)" "unprognostic (3.17e-2)" "unprognostic (2.22e-2)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (2.40e-1)" "prognostic favorable (4.52e-5)" "unprognostic (3.15e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (6.99e-2)" "unprognostic (1.06e-2)" "unprognostic (6.41e-2)" 6.3 5.3 3.5 6.0 2.9 8.5 6.6 2.0 6.3 8.0 2.7 6.2 5.7 6.7 3.0 5.8 9.8 3.9 5.8 2.9 0.5 7.6 10.8 6.5 6.9 1.7 1.1 8.0 11.3 5.9 11.2 3.7 0.9 8.0 4.1 5.4 6.6 4.6 6.3 8.2 7.2 4.5 0.1 10.1 6.0 19.7 0.9 5.2 8.6 2.4 6.0 6.7 6.4 2.2 9.2 10.5 10.6 14.8 6.7 12.9 19.4 11.7 7.8 12.0 9.5 24.3 8.2 14.0 8.2 9.3 8.3 29.0 12.9 15.0 7.1 19.9 20.3 9.5 30.3 11.6 5.9 20.2 10.8 10.3 12.4 10.4 9.8 10.4 10.8 11.3 19.8 10.1 8.4 20.6 11.7 22.7 21.9 14.5 13.7 19.0 10.7 19.9 6.9 16.4 30.4 21.2 11.7 19.1 6.2 9.1 19.7 11.6 15.4 12.3 11.2 22.3 16.9 6.3 7.9 11.2 8.6 9.3 7.3 0.0 0.5 0.4 0.7 0.3 0.3 0.5 0.3 0.3 0.1 1.5 0.2 0.1 1.0 0.7 0.1 0.5 0.2 0.1 3.5 2.9 2.0 6.3 2.9 0.5 1.7 1.1 0.9 0.1 0.9 2.2 3.6 6.4 9.0 12.1 4.8 5.4 2.8 3.9 5.7 8.2 6.0 5.0 5.9 5.7 3.8 3.7 2.1 2.6 5.9 5.4 0.0 6.2 4.1 15.1 5.6 4.1 5.3 7.0 12.2 4.5 2.0 4.1 4.6 7.1 1.3 7.0 5.7 8.1 3.2 3.3 8.5 5.0 10.2 4.2 7.7 2.5 5.0 3.4 0.0 5.6 3.2 4.4 3.1 7.1 5.5 6.8 5.8 4.9 4.6 3.7 3.6 4.3 20.3 12.2 0.0 4.2 4.4 9.5 10.0 3.0 6.8 1.4 5.7 6.2 6.1 2.9 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 156.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 219.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: AB_2677353, HPA044248: AB_2678873" "unprognostic (7.87e-2)" "prognostic favorable (1.95e-4)" "unprognostic (6.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.04e-1)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (8.99e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" "unprognostic (6.03e-3)" 15.2 29.3 80.7 20.6 81.4 32.7 16.1 95.2 98.3 14.0 74.4 27.2 12.9 15.9 16.3 20.1 16.0 10.4 85.3 81.7 81.0 25.0 39.2 10.8 32.6 86.3 82.7 19.8 19.7 24.6 30.7 8.7 87.0 19.8 17.5 12.4 22.9 13.8 131.6 10.9 16.5 15.1 81.8 19.0 27.6 11.0 88.0 22.5 17.7 84.5 31.2 17.2 11.9 80.1 50.1 111.2 60.7 70.8 21.2 24.9 29.5 41.4 26.5 90.7 76.1 150.4 47.5 157.3 48.3 34.2 48.6 50.4 111.8 76.2 69.2 57.3 87.8 91.6 155.3 152.9 22.4 168.9 103.9 32.1 27.0 80.8 22.4 19.6 49.6 93.5 139.2 36.5 52.2 236.5 89.5 70.0 72.8 88.4 54.5 141.9 64.6 186.9 48.6 34.7 66.2 42.9 93.4 119.8 20.7 59.0 77.5 80.8 39.3 40.0 49.6 51.8 67.2 37.6 96.9 248.2 21.3 89.5 62.3 15.1 25.5 93.3 14.9 40.3 17.9 74.3 15.1 17.9 49.6 75.1 15.9 16.3 17.2 22.5 35.9 219.7 26.1 23.2 80.7 81.4 95.2 98.3 81.7 81.0 86.3 82.7 87.0 81.8 88.0 80.1 16.5 12.8 14.3 6.8 53.4 18.6 27.2 39.5 14.8 17.9 48.1 51.9 113.0 18.6 29.3 33.1 4.2 54.6 62.3 30.9 156.5 41.6 3.0 27.3 23.8 18.9 44.0 58.5 9.9 51.4 63.3 29.3 30.1 36.9 4.5 62.3 16.4 67.5 114.5 11.8 9.8 34.5 69.2 26.4 59.8 6.5 21.5 36.2 62.2 5.6 94.3 89.0 32.0 4.5 6.5 31.0 44.8 29.7 65.9 31.5 24.0 87.6 53.2 14.5 6.6 29.4 35.7 33.7 44.8 35.8 21.9 26.1 22.4 105.0 53.5 27.7 SNRPA1 "Lea1, U2A'" ENSG00000131876 "Small nuclear ribonucleoprotein polypeptide A'" P09661 15 101281510-101295282 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045622, HPA048499" Supported Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA 48000 "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA045622: AB_2679394, HPA048499: AB_2680421" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (8.09e-2)" "unprognostic (2.20e-1)" "unprognostic (8.08e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (8.56e-5)" "unprognostic (5.80e-2)" "unprognostic (1.66e-3)" "prognostic favorable (8.83e-5)" "unprognostic (4.74e-2)" "unprognostic (6.77e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.06e-2)" "unprognostic (2.84e-1)" "unprognostic (2.43e-1)" "unprognostic (1.37e-2)" 19.0 18.2 11.0 35.5 11.4 68.1 20.8 13.2 15.4 14.7 14.7 30.6 24.3 15.5 33.0 33.8 18.6 12.7 25.8 12.0 11.6 25.2 25.5 19.5 43.3 11.5 11.3 13.6 22.2 18.3 13.9 30.4 11.7 16.3 30.8 15.5 23.1 12.6 19.7 18.5 30.1 19.3 10.9 25.2 23.2 37.8 12.4 37.4 18.3 12.4 51.9 26.3 18.2 12.6 175.5 119.5 112.7 57.4 31.3 25.6 111.3 158.2 72.8 139.2 105.1 255.8 150.7 192.9 89.2 107.8 109.0 101.7 170.2 113.1 148.1 98.0 262.5 151.4 196.7 137.3 24.0 175.1 103.7 21.0 83.0 89.0 111.3 30.9 90.9 147.1 216.1 175.8 86.5 194.6 177.6 185.7 144.5 232.0 100.1 174.5 121.7 194.8 103.3 450.2 88.6 92.7 97.2 109.0 125.1 117.1 105.2 136.4 66.2 74.1 141.0 86.8 160.3 143.5 464.8 378.9 59.9 162.9 89.3 3.8 36.6 21.5 55.7 47.2 55.3 53.0 57.7 56.1 58.0 47.4 46.6 59.0 6.8 48.5 44.0 54.7 68.9 39.0 11.0 11.4 13.2 15.4 12.0 11.6 11.5 11.3 11.7 10.9 12.4 12.6 41.5 19.2 54.6 16.3 71.6 65.6 73.4 141.6 70.6 37.8 41.8 52.6 30.5 18.6 80.3 36.8 12.5 124.3 69.6 37.4 68.4 94.6 96.2 52.7 42.5 47.2 27.0 61.4 30.9 109.0 154.1 51.5 27.0 55.6 65.8 37.7 21.4 35.5 67.0 37.0 29.2 44.2 126.1 24.1 39.2 22.4 34.8 36.4 42.7 13.1 76.4 39.6 47.4 16.6 28.6 95.3 41.8 28.6 76.1 142.3 78.7 87.1 89.2 34.9 13.1 37.9 67.1 192.9 65.9 68.3 50.6 112.3 68.1 42.3 52.4 101.6 SNRPD3 "Sm-D3, SMD3" ENSG00000100028 "Small nuclear ribonucleoprotein D3 polypeptide" P62318 22 24555958-24582052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA001170 Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA001170: AB_1080042" "unprognostic (3.30e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (4.44e-2)" "unprognostic (1.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.52e-2)" "unprognostic (3.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" 30.5 31.1 24.7 35.2 25.7 39.2 37.5 29.6 34.8 31.8 25.7 50.5 33.2 35.5 35.5 43.5 36.7 20.2 35.3 25.0 25.8 48.0 64.9 26.9 47.7 23.7 23.9 34.3 23.7 51.2 27.0 24.7 25.5 33.8 40.7 54.1 29.7 31.9 103.7 28.8 35.7 29.5 23.6 34.3 36.5 24.7 25.0 74.4 38.9 86.2 53.3 39.5 32.3 30.7 182.5 45.7 188.6 58.5 70.1 57.7 56.1 173.1 74.8 166.1 148.1 61.4 65.8 158.7 70.1 109.2 83.0 130.7 252.1 219.3 175.5 107.9 188.8 152.4 95.4 113.9 66.2 408.0 95.7 66.5 93.8 186.3 86.6 81.8 120.6 139.8 116.2 60.5 61.5 56.8 187.0 82.6 98.9 237.8 61.9 179.5 190.7 66.6 154.5 130.0 82.2 95.6 83.4 62.7 87.7 162.7 102.3 97.5 135.5 127.0 126.3 74.3 126.2 74.3 168.2 283.7 70.1 127.1 91.4 18.5 42.9 53.9 35.6 50.2 37.6 60.5 38.4 39.2 54.2 50.7 36.6 41.3 18.6 51.1 51.1 49.7 41.1 47.4 24.7 25.7 29.6 34.8 25.0 25.8 23.7 23.9 25.5 23.6 25.0 30.7 120.0 96.1 81.8 7.5 118.2 108.6 115.3 293.1 133.1 61.1 94.2 138.8 95.9 101.5 162.9 130.6 35.5 239.5 123.1 112.6 291.6 161.9 91.0 176.6 157.7 96.8 111.0 139.4 8.1 114.8 228.8 121.0 92.2 147.9 86.2 145.3 66.0 203.3 176.4 38.7 8.7 134.2 168.9 74.5 84.8 85.1 116.2 98.1 67.6 10.3 151.0 134.3 86.5 8.0 13.4 129.4 118.2 118.5 120.7 96.8 191.7 310.5 135.2 68.9 65.7 102.8 209.6 111.1 131.4 164.9 113.7 180.3 111.9 176.2 139.0 113.3 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 285.7;Hofbauer cells: 148.7;Kupffer cells: 215.5;Macrophages: 166.5;monocytes: 152.3;Muller glia cells: 310.5;Proximal tubular cells: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 336.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 103.1;U-937: 87.3;WM-115: 297.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported Nucleoplasm,Nucleoli,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Microtubules" Nucleoli "HPA015605: AB_1857342, HPA064782: AB_2685349" "unprognostic (6.42e-2)" "unprognostic (2.72e-3)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.92e-2)" "unprognostic (2.48e-3)" "unprognostic (4.51e-2)" "unprognostic (4.87e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (8.06e-5)" "unprognostic (1.12e-2)" "unprognostic (3.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.50e-1)" 23.7 14.5 26.4 34.7 27.8 42.1 11.0 17.6 45.9 4.5 6.1 5.6 4.1 9.0 1.1 2.9 3.0 8.8 1.8 30.2 42.2 37.8 69.1 41.2 36.9 29.1 28.2 1.1 7.8 1.3 4.7 10.9 40.3 3.5 6.4 47.1 1.7 2.1 1.0 1.4 6.2 9.5 18.6 42.1 3.9 5.1 32.0 15.8 2.9 2.7 24.8 10.9 1.6 26.8 55.8 5.0 0.2 10.1 0.1 0.0 57.8 0.0 3.9 0.1 0.0 0.5 18.4 24.0 41.4 0.0 36.2 1.7 13.5 3.6 0.0 33.3 12.4 2.5 0.4 36.3 0.1 52.2 8.9 0.6 5.4 0.0 4.2 0.1 0.8 30.7 1.5 0.3 0.0 9.7 22.2 54.3 15.3 0.9 5.1 0.1 0.1 1.3 103.1 12.0 22.5 7.1 11.7 8.5 62.7 18.1 15.2 72.6 0.3 0.1 12.2 0.2 13.7 17.9 15.5 16.4 0.5 87.3 297.4 55.9 144.7 3.7 18.6 158.5 18.2 82.3 13.2 16.4 101.2 71.7 6.9 12.0 336.7 47.7 162.5 37.0 29.6 70.0 26.4 27.8 17.6 45.9 30.2 42.2 29.1 28.2 40.3 18.6 32.0 26.8 3.3 3.2 14.7 6.8 63.4 5.4 1.2 0.7 1.8 20.3 17.6 9.5 1.8 34.3 4.4 23.9 2.1 14.9 18.6 2.5 285.7 66.0 1.3 2.1 40.7 7.6 9.5 19.1 63.1 27.1 111.8 3.4 0.0 2.3 31.1 2.9 2.2 109.8 148.7 35.3 53.4 3.3 0.0 215.5 130.3 2.1 1.2 166.5 8.8 19.7 152.3 310.5 33.0 7.1 8.5 14.1 1.5 0.0 8.0 4.4 4.5 204.9 0.8 23.2 0.0 0.7 4.7 7.1 29.5 0.8 3.0 28.7 31.6 0.9 8.7 1.3 SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.6;Enteroendocrine cells: 7.8;granulocytes: 8.2;monocytes: 7.9;Paneth cells: 8.0;Proximal enterocytes: 6.5;Undifferentiated cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" 17.1 13.3 17.3 10.2 18.5 10.5 15.3 19.4 19.2 16.6 9.0 22.5 15.3 15.8 6.4 14.9 12.9 7.4 15.0 18.4 17.1 17.0 10.1 11.9 9.3 19.3 18.2 14.8 12.7 10.7 9.4 7.3 16.1 12.9 8.8 5.8 12.3 10.9 25.7 17.5 16.8 8.9 16.1 10.8 16.4 5.3 17.8 9.4 10.6 15.5 7.4 18.0 14.9 18.5 31.1 22.3 14.7 14.2 17.3 12.4 7.9 10.0 13.6 23.3 21.3 17.6 23.7 30.7 16.7 17.4 29.3 16.8 16.8 15.2 9.8 47.0 14.0 15.8 18.2 30.2 18.3 10.7 24.5 10.6 22.2 24.7 14.5 13.0 14.1 22.6 27.0 19.6 12.5 18.8 29.2 36.8 15.5 12.0 21.9 23.7 8.4 34.0 17.6 6.7 25.6 19.2 25.3 23.0 23.2 9.7 23.4 18.6 27.5 23.5 22.9 24.1 14.7 20.9 38.3 30.3 23.2 14.5 8.4 9.2 13.6 13.6 7.6 16.2 6.2 8.9 7.8 6.8 9.4 8.7 5.6 5.1 2.1 4.3 23.6 6.4 8.3 7.3 17.3 18.5 19.4 19.2 18.4 17.1 19.3 18.2 16.1 16.1 17.8 18.5 0.3 0.0 3.3 0.0 0.8 1.0 0.1 0.4 4.0 0.0 0.5 0.3 0.4 0.0 0.2 0.0 0.0 0.4 0.1 5.6 0.0 4.8 0.0 0.1 0.2 0.9 7.8 1.3 0.0 3.1 0.6 0.4 1.1 0.1 8.2 0.4 0.7 0.1 1.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 7.9 0.2 0.0 0.0 0.0 3.9 8.0 0.4 1.1 0.0 6.5 0.6 0.7 0.4 0.0 0.7 1.0 0.0 0.0 1.5 0.4 0.4 1.1 0.2 5.6 0.1 SNX29 "FLJ12363, RUNDC2A" ENSG00000048471 "Sorting nexin 29" Q8TEQ0 16 11976734-12574287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 354.5;Late spermatids: 430.7;Microglial cells: 169.6;Oligodendrocytes: 241.6;Rod photoreceptor cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 22.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008889, HPA062810" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Nucleoli, Cytosol" "HPA008889: AB_1079856, HPA062810: " "unprognostic (2.50e-1)" "unprognostic (4.12e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (9.82e-3)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (5.38e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" "unprognostic (6.08e-2)" "prognostic favorable (1.38e-7)" "unprognostic (3.85e-3)" "unprognostic (4.54e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (1.03e-4)" 8.6 3.5 7.4 8.2 18.8 9.5 6.2 13.6 11.8 6.6 7.4 5.3 2.3 5.8 2.6 8.2 8.4 4.8 4.5 7.5 9.9 19.0 2.3 6.8 13.0 17.0 15.6 10.2 3.5 22.5 7.1 8.0 18.3 3.5 3.4 23.8 5.6 4.8 6.0 6.9 4.6 5.7 11.4 9.0 4.3 8.5 17.9 21.0 6.5 5.7 16.0 6.3 5.0 26.7 5.0 2.9 4.4 3.5 25.4 20.8 5.7 10.7 29.1 4.3 4.7 0.6 5.7 18.7 13.9 16.6 2.8 4.2 2.9 6.8 6.2 7.2 3.0 2.5 2.5 6.4 4.9 2.7 6.6 19.1 4.4 6.3 2.8 6.5 7.6 6.1 3.9 5.2 4.4 6.7 5.0 3.1 2.4 3.2 2.6 11.3 5.6 15.2 19.3 4.6 5.2 4.4 12.2 7.2 2.5 3.8 4.1 3.2 11.7 7.6 3.0 5.8 2.1 29.5 24.4 11.5 14.1 2.8 4.9 3.8 6.9 1.6 2.0 4.5 2.5 10.6 4.3 2.7 2.5 22.3 5.2 3.6 2.5 1.3 2.3 7.4 4.0 1.9 7.4 18.8 13.6 11.8 7.5 9.9 17.0 15.6 18.3 11.4 17.9 26.7 14.4 12.8 22.9 71.2 61.0 15.3 6.5 5.3 19.9 63.9 8.5 7.4 9.7 4.3 10.8 16.5 354.5 18.6 26.9 4.4 21.5 4.6 124.0 35.3 27.8 13.8 13.1 6.1 59.0 2.9 5.0 20.8 14.8 62.6 42.5 15.2 17.9 4.8 28.7 92.5 54.6 4.6 8.2 29.3 39.6 430.7 21.5 36.7 12.4 169.6 24.3 23.1 16.5 51.8 241.6 7.7 4.3 15.4 23.9 3.6 3.3 42.6 27.2 256.1 6.6 20.8 14.2 20.0 10.8 21.9 15.5 17.1 15.4 14.1 4.0 5.5 SNX30 ATG24A ENSG00000148158 "Sorting nexin family member 30" Q5VWJ9 9 112750760-112881671 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 77.9;Oligodendrocytes: 91.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019346 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli, Cytosol" "HPA019346: AB_2286395" "unprognostic (1.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.08e-1)" "unprognostic (3.61e-1)" "unprognostic (3.61e-1)" "unprognostic (3.69e-1)" "unprognostic (8.05e-3)" "unprognostic (2.04e-3)" "unprognostic (4.48e-2)" "unprognostic (3.59e-3)" "unprognostic (3.39e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.01e-7)" "unprognostic (4.48e-3)" "unprognostic (1.18e-1)" "unprognostic (7.51e-2)" "unprognostic (1.41e-2)" 3.5 3.6 8.0 7.3 16.5 8.4 6.8 9.7 12.3 9.1 0.0 10.2 7.1 5.5 3.4 3.8 3.1 4.7 3.0 7.9 13.5 21.2 4.6 21.3 8.6 14.5 12.9 5.7 4.6 5.2 3.0 4.5 12.2 3.4 10.3 4.0 5.0 3.5 2.0 4.8 8.2 6.5 8.6 7.0 4.2 11.9 16.1 3.8 2.6 2.1 8.1 4.0 3.2 25.8 8.2 5.0 8.5 6.8 10.5 9.6 7.2 6.9 14.2 5.7 5.4 18.1 1.9 13.6 5.7 17.9 10.2 9.6 10.4 4.1 8.8 4.4 4.9 4.2 4.6 7.3 7.5 4.2 7.2 7.8 5.6 8.8 6.5 14.4 4.9 3.4 6.7 7.5 7.8 5.7 2.8 4.9 9.4 13.2 5.2 5.9 19.9 3.5 11.1 14.2 12.6 4.0 9.0 12.3 17.6 8.7 9.2 7.4 5.6 8.4 9.0 25.0 5.9 19.6 19.5 6.3 10.8 3.9 16.9 0.0 2.0 0.6 0.2 0.7 0.6 0.0 0.3 0.4 1.6 0.2 0.2 0.2 0.2 0.3 0.8 0.2 0.6 0.7 8.0 16.5 9.7 12.3 7.9 13.5 14.5 12.9 12.2 8.6 16.1 25.8 4.4 6.4 77.9 11.4 3.5 8.2 2.0 3.1 7.4 5.9 10.5 5.5 4.3 2.8 7.6 5.5 10.4 0.6 3.6 26.2 5.9 2.6 9.1 16.2 7.5 4.8 4.8 6.6 39.0 3.2 2.1 5.3 5.6 20.1 7.0 15.6 8.9 7.7 13.4 8.4 24.1 10.8 2.0 22.4 17.0 8.1 5.6 19.8 21.4 36.5 22.3 2.4 2.1 22.6 91.2 4.4 20.3 7.9 5.8 2.5 11.9 34.2 2.3 3.1 0.0 4.7 2.8 6.6 10.0 7.3 11.1 0.4 5.7 3.7 9.6 6.3 SNX31 MGC39715 ENSG00000174226 "Sorting nexin 31" Q8N9S9 8 100572889-100663415 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 6.5;urinary bladder: 16.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 81.8" "Cancer enriched" "Detected in many" 22 "urothelial cancer: 24.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RT4: 80.7" "Region enriched" "Detected in single" 5 "thalamus: 2.6" "Not detected" "Not detected" "HPA024284, HPA053466" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024284: AB_1853894, HPA053466: AB_2682161" "unprognostic (1.39e-1)" "unprognostic (3.83e-2)" "unprognostic (7.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.20e-5)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "prognostic favorable (1.47e-4)" "unprognostic (2.54e-1)" "unprognostic (4.05e-2)" 0.6 0.1 1.0 0.0 1.2 0.2 0.4 0.8 3.1 0.4 0.6 0.3 0.0 0.3 0.2 6.5 0.3 1.1 1.7 1.0 1.1 0.2 0.5 0.1 0.4 0.0 0.0 0.4 0.3 0.3 0.2 0.0 0.0 1.4 0.1 0.2 1.2 0.2 0.6 0.6 0.1 0.5 0.4 0.1 0.7 4.0 0.7 0.3 0.5 0.5 3.6 16.4 1.7 1.5 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.0 0.0 0.0 80.7 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.0 1.2 0.8 3.1 1.0 1.1 0.0 0.0 0.0 0.4 0.7 1.5 0.5 0.0 0.0 6.2 0.1 0.4 3.3 0.2 9.6 0.0 0.2 0.6 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 81.8 0.2 0.1 0.4 0.0 0.0 12.8 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 19.7 0.6 0.2 0.0 1.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 1.2 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.3 3.7 0.3 0.5 9.7 0.4 0.0 0.1 0.0 0.0 6.0 SOCS5 "CIS6, Cish5, CISH6, KIAA0671, SOCS-5" ENSG00000171150 "Suppressor of cytokine signaling 5" O75159 2 46698952-46780245 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 121.0;fHDF/TERT166: 121.9;U-138 MG: 80.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020884, CAB025510" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB025510: , HPA020884: AB_1857356" "unprognostic (1.69e-1)" "unprognostic (1.98e-2)" "unprognostic (5.71e-2)" "unprognostic (1.64e-2)" "unprognostic (2.20e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (4.52e-2)" "unprognostic (9.13e-2)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.10e-3)" "unprognostic (3.01e-1)" "unprognostic (1.47e-3)" "unprognostic (8.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" 12.0 10.2 7.6 6.3 7.7 7.7 13.0 15.9 9.6 13.0 7.5 9.7 5.2 14.1 9.1 8.5 9.3 11.3 11.3 8.1 7.6 9.2 6.7 8.7 6.7 8.3 8.3 23.2 6.2 14.2 5.6 7.3 8.5 9.9 6.6 12.7 8.7 12.4 9.0 7.5 6.7 13.9 8.5 9.0 6.6 10.3 8.2 7.6 9.9 16.0 6.7 9.3 8.5 8.6 14.5 10.8 9.3 13.8 29.9 42.3 11.4 66.5 121.0 31.5 18.6 10.3 6.9 7.5 12.7 121.9 9.7 7.1 9.9 10.8 41.2 7.3 9.4 11.8 10.0 13.2 18.4 6.9 12.7 33.9 15.8 26.7 10.7 35.8 11.0 3.0 10.2 8.1 21.5 5.3 5.9 12.0 10.4 15.1 8.7 7.8 15.9 9.5 13.2 11.1 7.3 19.8 16.4 10.7 13.0 8.9 4.4 10.3 12.8 80.0 17.7 26.9 13.2 9.7 6.4 6.5 36.9 13.7 25.5 0.5 0.4 2.5 0.9 0.4 1.1 1.8 0.5 0.6 0.5 3.0 1.1 1.5 0.4 1.0 1.7 0.5 1.0 0.7 7.6 7.7 15.9 9.6 8.1 7.6 8.3 8.3 8.5 8.5 8.2 8.6 17.2 3.2 6.1 18.9 11.3 16.6 7.2 8.3 16.5 12.8 15.1 12.2 14.2 18.6 8.0 3.7 22.9 3.7 6.2 11.0 5.9 7.3 12.3 9.9 29.2 24.3 10.8 6.1 43.4 6.8 2.5 18.8 10.2 12.0 17.1 17.4 17.2 7.9 4.5 18.5 51.5 7.1 2.0 8.4 15.2 8.1 17.4 7.7 7.2 18.7 8.4 9.7 6.2 38.2 25.4 6.8 8.8 17.0 7.0 11.0 5.1 7.3 5.3 5.5 13.1 13.8 20.1 13.3 18.8 9.9 14.5 2.7 7.0 7.3 5.6 7.8 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SOX30 ENSG00000039600 "SRY-box transcription factor 30" O94993 5 157625679-157671480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 80.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 351.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.9;CACO-2: 1.3;HDLM-2: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006159, CAB009382" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 36: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "CAB009382: AB_2195963, HPA006159: AB_1080062" "unprognostic (3.51e-2)" "unprognostic (4.72e-2)" "unprognostic (7.31e-2)" "unprognostic (4.70e-4)" "unprognostic (2.53e-2)" "unprognostic (6.12e-2)" "unprognostic (4.47e-2)" "unprognostic (2.22e-2)" "unprognostic (5.33e-2)" "unprognostic (1.36e-1)" "unprognostic (4.73e-2)" "unprognostic (7.85e-2)" "unprognostic (4.64e-4)" "unprognostic (5.88e-2)" "unprognostic (1.64e-1)" "unprognostic (3.72e-2)" "unprognostic (3.45e-1)" 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.1 80.6 0.4 0.7 0.0 0.0 0.1 0.1 0.0 0.2 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 1.3 0.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 4.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.5 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.0 351.1 0.5 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 71.4 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 42.8 11.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 SP6 "Epfn, KLF14" ENSG00000189120 "Sp6 transcription factor" Q3SY56 17 47844908-47855874 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.8;skin 1: 14.6" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 57.5;Syncytiotrophoblasts: 98.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 11.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024516, HPA044469" Supported "Nucleoplasm,Mitotic spindle,Centrosome" Yes No "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Mitotic spindle, Centrosome" "HPA024516: AB_10960551, HPA044469: AB_10966430" "unprognostic (3.06e-2)" "unprognostic (4.32e-2)" "unprognostic (1.07e-2)" "unprognostic (7.55e-3)" "unprognostic (6.79e-2)" "unprognostic (4.57e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.22e-1)" "unprognostic (8.72e-2)" "unprognostic (3.92e-3)" "unprognostic (1.63e-1)" "unprognostic (9.59e-3)" "prognostic favorable (6.39e-4)" "unprognostic (3.33e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.72e-4)" 0.9 0.9 0.1 0.6 0.1 0.0 3.9 0.4 0.1 1.3 0.1 1.4 1.6 0.3 3.9 5.5 1.1 0.1 0.3 0.1 0.2 1.0 0.0 3.1 0.6 0.7 0.4 0.9 0.4 6.2 0.2 22.8 1.0 1.8 0.7 0.1 0.9 10.2 0.1 14.6 4.7 0.3 0.5 0.8 0.3 0.2 0.2 1.1 1.1 0.1 1.9 2.7 3.9 0.1 6.8 0.8 0.0 0.0 0.0 0.0 92.3 0.4 0.4 1.8 0.4 20.1 1.9 0.0 0.6 0.0 1.3 2.8 0.1 3.4 0.5 0.2 0.7 0.1 1.5 0.6 0.1 0.0 0.0 0.1 1.8 0.0 1.8 0.2 0.2 0.2 4.7 0.1 0.1 1.8 0.0 0.1 0.0 8.2 1.6 0.0 0.0 0.2 0.5 11.9 2.9 0.1 0.1 11.9 0.0 16.8 4.8 0.0 6.3 0.4 2.6 0.0 0.5 0.8 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.2 0.7 0.4 1.0 0.5 0.2 0.1 1.3 0.0 0.0 1.0 0.2 0.1 2.6 4.6 4.0 0.0 6.0 6.1 0.5 0.0 0.8 1.8 0.0 57.5 0.3 5.2 0.0 0.7 0.1 0.4 0.1 2.7 1.8 0.0 0.2 0.8 3.9 0.7 0.0 0.7 0.0 0.2 0.7 0.1 4.1 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 3.2 0.0 0.1 3.8 13.4 0.0 1.0 0.0 0.0 0.0 0.2 0.3 0.6 1.1 0.9 98.8 0.3 0.1 3.3 6.3 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPANXN4 "CT11.9, SPANX-N4" ENSG00000189326 "SPANX family member N4" Q5MJ08 X 143025918-143034702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 25.9" "Group enriched" "Detected in some" 165 "Early spermatids: 97.7;Late spermatids: 298.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045730, HPA059094" Uncertain Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Nuclear membrane" "HPA045730: AB_10961036, HPA059094: " 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 298.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPATA12 ENSG00000186451 "Spermatogenesis associated 12" Q7Z6I5 3 57060664-57075432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 20.5" "Group enriched" "Detected in some" 145 "Early spermatids: 464.2;Late spermatids: 1195.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.9;RH-30: 1.1" "HPA043323, HPA075578" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA043323: AB_10796792, HPA075578: " "unprognostic (2.31e-1)" "unprognostic (2.18e-4)" "unprognostic (3.47e-4)" "unprognostic (2.21e-2)" "unprognostic (2.66e-1)" "unprognostic (8.79e-3)" "unprognostic (1.69e-3)" "unprognostic (3.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (6.80e-2)" "unprognostic (1.76e-2)" "unprognostic (4.71e-3)" "unprognostic (7.29e-2)" "unprognostic (1.62e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-3)" 0.0 0.3 0.4 0.0 0.3 0.0 0.0 0.2 0.2 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.0 0.3 0.2 2.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 20.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.1 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.3 0.0 0.7 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.2 0.2 0.6 2.0 0.8 0.7 0.5 0.4 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.4 464.2 1.0 0.1 0.6 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 1.3 0.0 1195.5 5.0 0.5 0.0 1.0 0.0 0.0 0.0 1.0 0.7 1.4 0.1 5.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 2.8 0.3 0.0 0.0 0.3 0.0 0.2 0.5 SPATA2L "C16orf76, MGC26885, tamo" ENSG00000158792 "Spermatogenesis associated 2 like" Q8IUW3 16 89696357-89701705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041182, HPA042453" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA041182: AB_2677352, HPA042453: AB_2678005" "unprognostic (1.22e-1)" "unprognostic (9.04e-2)" "unprognostic (5.23e-2)" "unprognostic (9.13e-3)" "unprognostic (2.21e-1)" "unprognostic (6.62e-2)" "unprognostic (2.72e-2)" "unprognostic (2.13e-1)" "unprognostic (4.86e-2)" "unprognostic (9.25e-2)" "unprognostic (1.40e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-3)" "unprognostic (8.86e-2)" "unprognostic (4.19e-2)" "unprognostic (5.84e-2)" "unprognostic (2.55e-1)" 6.7 5.1 5.7 2.3 6.6 5.0 4.9 4.8 8.7 3.9 5.2 6.2 5.9 6.1 0.7 5.8 6.2 2.2 4.9 8.0 4.9 10.3 13.6 7.1 1.5 4.9 3.8 5.4 14.2 2.2 16.7 1.8 3.1 5.9 0.8 0.6 5.7 1.3 1.3 7.7 7.1 1.4 2.6 6.0 6.9 4.9 4.2 1.7 7.0 0.3 0.8 3.8 3.5 6.3 7.4 5.8 2.0 9.6 1.5 1.6 10.7 4.9 2.3 2.3 1.5 11.1 6.2 2.5 6.6 1.6 3.1 12.5 1.8 2.8 0.5 2.5 19.9 1.7 2.2 15.3 5.1 1.3 5.0 1.6 3.5 3.6 1.1 2.6 2.6 2.9 7.7 1.7 1.6 34.0 4.3 8.0 5.4 7.6 7.5 9.4 1.0 7.4 3.4 2.6 11.0 7.0 5.3 5.4 6.5 0.9 14.0 5.7 6.7 2.3 8.5 0.4 2.3 4.2 2.8 2.3 6.9 4.1 4.4 2.8 4.0 5.3 5.5 6.5 3.9 3.7 3.9 4.2 4.4 4.1 3.5 3.9 13.7 2.1 4.9 4.6 3.7 4.1 5.7 6.6 4.8 8.7 8.0 4.9 4.9 3.8 3.1 2.6 4.2 6.3 5.9 3.2 0.5 2.3 10.8 15.7 18.7 7.7 5.2 9.5 11.0 6.6 0.4 7.2 3.1 11.0 0.0 8.7 18.4 27.8 1.9 13.7 7.4 7.6 3.2 6.3 23.8 0.0 13.6 13.8 5.7 6.4 9.2 9.3 4.5 2.1 6.1 5.7 7.4 3.3 7.1 7.6 14.2 6.1 13.2 1.5 2.8 9.1 8.8 2.8 4.3 6.6 8.2 2.5 1.3 12.7 21.8 2.2 8.6 12.7 32.3 10.3 1.5 8.0 0.0 9.3 7.0 2.7 2.5 2.6 19.9 24.9 10.5 4.7 9.3 11.7 SPATA6 "FLJ10007, SRF-1, SRF1" ENSG00000132122 "Spermatogenesis associated 6" Q9NWH7 1 48295373-48472208 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.1" "Group enriched" "Detected in many" 5 "Early spermatids: 1475.4;Late spermatids: 4697.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.9" "Group enriched" "Detected in many" 4 "granulocytes: 3.6;monocytes: 5.9" "Cell line enhanced" "Detected in many" "AN3-CA: 12.9;ASC TERT1: 20.9;HSkMC: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028234 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA028234: AB_2672532" "unprognostic (1.36e-2)" "unprognostic (2.96e-2)" "unprognostic (3.38e-2)" "unprognostic (2.87e-2)" "unprognostic (3.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.77e-2)" "unprognostic (4.69e-3)" "unprognostic (2.40e-2)" "unprognostic (2.61e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (3.41e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (7.89e-2)" "unprognostic (5.71e-3)" 6.0 8.1 6.2 2.0 9.7 1.0 7.2 6.9 6.4 7.8 7.2 5.2 2.7 5.8 6.1 3.4 15.3 4.9 4.4 5.9 8.0 6.1 1.7 5.9 2.2 8.6 8.5 8.9 4.6 10.6 8.6 4.7 8.6 5.4 3.9 13.3 6.3 7.4 1.7 4.4 3.3 4.4 7.3 3.7 6.7 50.1 9.6 3.2 9.5 3.7 1.6 6.0 6.3 11.9 0.2 1.2 11.6 12.9 10.5 20.9 1.6 1.3 4.9 0.9 0.8 0.1 0.8 0.0 0.7 2.1 6.1 0.3 0.9 2.9 0.8 0.9 1.6 0.1 0.5 0.6 2.2 0.0 0.8 15.0 2.2 1.9 0.7 6.3 4.7 1.8 0.1 0.0 4.9 0.4 0.1 0.2 4.9 0.9 1.2 3.7 0.0 1.1 7.1 2.0 2.8 6.3 4.8 0.4 11.3 9.5 2.8 0.7 1.4 1.7 1.7 2.7 1.9 0.0 0.0 0.0 7.0 0.1 7.7 0.0 1.2 3.6 0.0 2.8 0.0 0.1 0.2 0.0 1.1 0.0 0.4 0.3 0.1 0.2 5.9 0.5 0.0 0.5 6.2 9.7 6.9 6.4 5.9 8.0 8.6 8.5 8.6 7.3 9.6 11.9 14.8 3.2 10.0 151.8 2.0 5.6 16.7 6.4 9.1 17.0 13.1 19.9 3.5 28.6 12.5 16.5 45.9 0.4 5.1 3.9 17.6 8.9 1475.4 77.3 18.9 10.5 9.6 2.1 43.9 10.2 0.6 29.8 35.2 9.0 16.5 5.0 16.1 2.4 5.1 32.0 35.0 5.7 12.2 17.9 9.2 4697.2 36.7 14.9 19.6 68.4 10.5 23.4 3.1 563.5 341.6 4.5 3.8 25.2 2.0 6.2 3.4 10.3 67.3 45.7 19.7 47.5 14.7 110.5 23.8 6.7 5.3 0.3 1.6 11.5 5.7 9.7 SPATA7 "HSD3, LCA3" ENSG00000042317 "Spermatogenesis associated 7" Q9P0W8 14 88384924-88470350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.0" "Group enriched" "Detected in many" 9 "Early spermatids: 946.9;Late spermatids: 1152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038082, HPA038083" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA038082: AB_10671738, HPA038083: AB_10671519" "unprognostic (2.09e-2)" "unprognostic (6.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.50e-3)" "unprognostic (3.22e-2)" "unprognostic (6.75e-2)" "unprognostic (1.29e-3)" "unprognostic (4.70e-2)" "unprognostic (1.70e-1)" "unprognostic (5.45e-3)" "prognostic favorable (4.16e-5)" "unprognostic (2.88e-1)" "prognostic favorable (2.50e-5)" "unprognostic (8.41e-2)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" "unprognostic (2.81e-2)" 5.8 6.0 8.6 1.6 10.4 1.7 6.0 28.4 9.5 7.2 6.7 5.8 2.2 6.6 7.0 2.8 8.3 5.5 5.4 8.6 10.4 9.5 5.1 4.6 1.8 8.6 9.2 12.3 7.9 7.6 11.1 2.8 8.6 6.6 3.1 10.2 4.1 4.6 5.0 5.6 3.2 4.7 8.9 3.6 5.0 57.0 9.2 3.0 12.1 4.5 1.2 5.4 4.9 11.2 2.3 3.7 5.5 7.5 8.8 16.5 6.0 5.2 9.3 5.1 3.4 1.2 4.5 2.2 2.5 5.7 3.8 2.3 2.5 4.0 4.8 3.2 1.8 0.5 1.9 2.1 12.7 3.9 0.5 7.8 6.6 2.1 3.9 16.8 9.4 5.0 1.3 2.7 4.8 2.8 2.8 3.7 1.4 2.9 4.6 3.9 5.6 1.3 8.1 1.9 3.9 4.9 5.1 6.7 5.0 6.5 6.0 4.2 4.9 3.7 4.0 5.2 2.9 2.6 2.1 1.3 6.2 1.1 2.6 0.0 1.0 0.2 2.1 1.4 2.5 1.9 1.7 1.0 2.1 0.4 1.0 1.8 0.8 0.4 0.9 2.1 0.7 1.0 8.6 10.4 28.4 9.5 8.6 10.4 8.6 9.2 8.6 8.9 9.2 11.2 7.8 12.8 7.3 38.5 1.5 2.4 7.6 9.8 7.4 10.8 6.3 8.5 12.0 7.2 8.8 3.7 20.9 2.6 5.3 1.1 9.8 11.0 946.9 22.3 13.2 6.8 16.3 1.3 113.0 7.2 3.6 11.8 4.1 4.2 1.3 19.4 7.9 4.5 5.7 15.2 91.6 4.0 12.2 17.2 2.8 1152.6 20.5 6.7 8.8 25.3 4.0 12.5 2.1 49.8 54.7 5.6 4.3 17.0 0.9 3.0 1.4 26.0 32.7 20.5 6.6 15.0 7.9 37.5 14.7 3.0 2.0 1.1 3.3 20.5 4.5 3.3 SPATC1L C21orf56 ENSG00000160284 "Spermatogenesis and centriole associated 1 like" Q9H0A9 21 46161148-46184476 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.9" "Group enriched" "Detected in many" 5 "Early spermatids: 208.9;Late spermatids: 472.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 3.7;cerebral cortex: 4.8;hippocampal formation: 2.9" "Immune cell enhanced" "Detected in many" "eosinophil: 36.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 37.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018979, HPA019165, HPA029394" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane, Cytosol" "HPA018979: AB_1845696, HPA019165: AB_1845697, HPA029394: AB_10601148" "unprognostic (1.46e-2)" "unprognostic (3.88e-2)" "unprognostic (3.95e-2)" "unprognostic (4.86e-2)" "unprognostic (6.36e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.56e-2)" "unprognostic (2.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-2)" "unprognostic (2.58e-1)" 7.6 23.4 4.2 1.0 3.7 1.3 8.5 0.0 4.8 11.4 0.0 9.7 1.3 9.8 0.6 7.7 6.8 1.4 11.5 2.9 0.6 7.3 1.3 5.9 1.6 0.4 0.1 13.9 11.3 1.6 14.2 1.1 0.1 32.5 0.7 0.3 6.7 2.5 5.6 10.5 6.9 0.8 0.0 8.4 8.3 48.9 0.9 1.0 6.3 0.8 1.0 9.8 11.7 0.1 2.9 0.0 3.6 6.7 2.0 4.7 1.9 4.1 2.2 2.2 1.7 0.0 1.8 9.0 8.0 5.0 2.6 0.5 0.0 3.2 0.6 8.3 6.6 21.6 1.3 5.0 0.1 0.0 8.5 5.0 1.5 0.0 0.0 4.2 7.2 10.1 37.8 13.2 3.1 5.7 7.0 2.5 15.0 4.0 18.0 15.4 4.9 10.0 3.4 0.8 1.1 6.9 3.2 1.7 8.6 2.5 5.6 8.3 0.4 6.5 8.0 9.3 6.3 21.9 12.6 6.6 8.6 11.9 6.1 1.5 5.7 36.1 4.3 6.8 5.6 7.6 6.2 5.9 8.6 7.6 9.7 9.2 0.3 6.6 4.7 7.2 7.0 3.6 4.2 3.7 0.0 4.8 2.9 0.6 0.4 0.1 0.1 0.0 0.9 0.1 20.5 0.0 0.0 3.6 13.5 23.6 11.6 21.4 18.2 6.8 11.9 14.6 1.9 12.8 6.9 3.7 0.0 3.4 10.1 7.7 15.6 16.8 208.9 6.3 14.6 15.4 60.4 12.8 2.6 20.5 17.7 18.1 13.7 8.8 0.0 18.8 14.6 0.6 13.7 3.3 2.0 16.4 8.2 8.8 24.4 472.3 32.3 9.9 28.4 1.0 5.9 5.8 6.2 3.0 3.1 17.8 6.6 31.6 28.0 24.1 6.8 13.4 2.8 3.1 19.7 12.0 14.0 17.8 14.7 17.0 40.1 3.1 11.7 4.0 18.3 8.1 SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 140.7;salivary gland: 114.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 94.2;Breast myoepithelial cells: 61.1;Intestinal goblet cells: 315.1;Prostatic glandular cells: 72.7" "Cancer enhanced" "Detected in many" "prostate cancer: 388.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 288.4;OE19: 118.0;SK-BR-3: 192.2;T-47d: 154.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.9" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" Cytosol "HPA055707: AB_2682894" "unprognostic (2.98e-1)" "unprognostic (9.68e-2)" "unprognostic (2.84e-1)" "prognostic favorable (9.26e-9)" "unprognostic (1.57e-1)" "unprognostic (7.10e-3)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (7.39e-3)" "unprognostic (3.48e-3)" "unprognostic (2.92e-1)" "unprognostic (6.16e-11)" "unprognostic (8.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-2)" 0.4 0.1 0.5 1.4 0.5 0.1 36.6 0.8 1.1 28.0 0.0 18.4 11.6 9.0 0.5 2.2 6.3 2.4 0.4 0.5 0.2 0.1 0.1 1.1 0.0 0.3 0.4 0.1 0.6 0.0 0.2 0.0 0.2 140.7 10.2 0.0 114.8 0.1 0.3 9.3 14.3 0.6 0.1 0.1 35.4 0.3 0.5 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 30.9 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.4 0.3 0.4 0.0 118.0 38.6 0.1 0.0 0.3 0.3 0.3 2.1 0.2 0.0 192.2 0.0 0.0 154.0 0.0 0.0 0.0 0.5 0.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 1.1 0.5 0.2 0.3 0.4 0.2 0.1 0.5 0.5 0.8 0.0 2.2 0.7 0.3 0.1 13.3 20.7 0.0 0.0 94.2 61.1 0.3 5.7 31.7 0.0 0.0 0.0 1.4 27.1 0.0 2.6 1.1 6.2 0.7 0.6 5.4 0.0 0.8 1.2 0.0 0.4 28.1 18.7 0.0 0.2 0.4 0.0 0.0 0.0 0.6 315.1 12.2 0.0 0.2 5.5 0.0 0.9 3.6 0.0 0.0 0.0 0.0 0.0 0.2 20.2 12.3 0.0 0.1 72.7 5.7 0.0 2.9 0.0 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.3 0.8 0.0 30.0 11.5 SPECC1 "CYTSB, FLJ36955, HCMOGT-1, NSP" ENSG00000128487 "Sperm antigen with calponin homology and coiled-coil domains 1" Q5M775 17 20008865-20319026 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.1;Inhibitory neurons: 220.8;Microglial cells: 187.4;Oligodendrocytes: 317.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 42.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SiHa: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021421, HPA021430, HPA061073" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA 9800 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center, Cytosol" "HPA021421: AB_1857431, HPA021430: AB_1857432, HPA061073: " "unprognostic (1.13e-3)" "unprognostic (2.39e-1)" "unprognostic (1.98e-2)" "unprognostic (8.10e-3)" "unprognostic (8.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (5.81e-2)" "unprognostic (6.23e-3)" "unprognostic (2.65e-1)" "unprognostic (3.15e-1)" "unprognostic (6.86e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" 12.5 9.6 30.8 7.3 35.1 23.6 9.2 24.1 43.7 6.1 22.3 15.1 9.8 12.8 4.7 9.2 8.3 14.8 5.0 41.4 21.4 4.7 1.2 5.7 5.3 32.8 25.8 16.6 4.8 3.3 6.4 3.6 24.5 6.1 10.0 6.1 6.2 5.0 5.1 3.6 10.5 9.5 21.0 13.5 10.3 22.8 41.1 3.0 5.2 2.8 5.2 4.6 4.3 47.3 26.2 37.3 15.7 7.2 14.7 6.9 29.1 10.0 12.4 12.4 21.4 67.6 17.1 1.5 45.3 11.4 24.3 21.1 10.7 33.4 3.7 12.8 18.5 14.5 34.4 10.5 4.9 1.3 5.6 10.6 36.9 10.2 24.9 46.8 0.0 4.4 1.0 15.1 10.4 24.0 0.3 5.3 14.5 17.0 6.3 11.8 49.5 23.6 32.2 11.4 7.1 6.9 75.7 35.6 13.9 62.2 26.3 9.1 0.3 0.5 21.1 0.9 30.8 5.4 11.7 0.9 19.1 12.6 6.5 42.1 15.8 33.0 2.2 8.4 3.2 1.8 1.5 3.4 26.6 1.4 1.0 1.4 11.1 13.0 7.9 4.6 0.6 5.5 30.8 35.1 24.1 43.7 41.4 21.4 32.8 25.8 24.5 21.0 41.1 47.3 28.7 22.4 14.7 170.4 5.7 5.5 12.5 22.0 10.8 7.4 5.8 4.7 10.3 7.2 21.1 18.4 68.8 5.5 10.2 56.8 9.8 30.9 100.0 40.1 44.1 13.1 7.7 82.5 217.1 36.3 11.5 18.6 34.1 64.1 116.4 29.5 3.9 0.2 22.0 0.0 220.8 54.8 12.2 12.4 15.9 54.5 5.0 29.0 21.4 187.4 84.7 13.6 11.3 125.2 317.8 67.7 24.7 44.8 7.0 19.7 25.2 3.6 18.1 31.4 59.2 7.3 81.3 73.8 68.9 5.9 2.6 2.2 10.0 87.8 27.4 21.5 SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.2" "Group enriched" "Detected in many" 4 "Early spermatids: 400.4;Spermatocytes: 455.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 17.8;BJ hTERT+ SV40 Large T+ RasG12V: 18.6;HBF TERT88: 21.7;HMC-1: 13.4;OE19: 15.9;RPTEC TERT1: 26.8;SCLC-21H: 19.9;WM-115: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" NA NA 52000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" 2.3 3.4 1.1 0.8 1.1 0.4 2.2 1.2 1.6 1.2 1.0 1.6 1.2 1.5 6.3 2.6 1.8 3.5 3.1 1.1 1.2 2.0 1.2 1.1 0.8 1.3 1.2 3.4 1.9 4.7 1.2 12.9 1.3 3.5 1.1 2.8 1.8 2.9 1.6 1.0 0.9 1.2 1.3 1.3 1.5 73.2 1.1 0.9 1.9 1.9 0.7 2.4 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 17.8 18.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.7 5.0 0.0 0.0 0.0 0.0 6.3 0.0 13.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 2.9 0.0 0.0 3.3 15.9 0.0 0.0 1.4 0.0 26.8 0.2 19.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 31.6 1.1 1.3 0.4 0.2 1.1 0.5 0.5 0.4 0.3 0.8 0.3 0.3 0.5 0.5 0.2 0.8 0.4 0.4 0.5 1.1 1.1 1.2 1.6 1.1 1.2 1.3 1.2 1.3 1.3 1.1 1.6 5.1 0.0 0.0 0.0 0.2 1.9 3.0 23.7 1.8 1.0 2.7 4.1 4.1 1.5 4.0 7.3 4.2 92.3 0.3 0.2 1.9 2.1 400.4 3.9 3.4 3.6 1.8 0.8 0.0 2.7 7.2 5.5 0.0 2.0 0.0 1.7 2.2 1.8 7.8 0.0 0.0 0.9 6.1 2.1 3.3 90.3 21.1 1.2 5.4 0.0 1.0 5.3 0.0 0.0 0.0 0.9 0.0 8.6 0.0 3.3 0.0 3.9 6.3 5.6 46.0 3.4 4.2 455.0 88.7 1.1 2.3 62.1 0.5 11.1 0.2 1.5 SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" 21.1 27.1 18.4 18.2 25.7 27.4 21.6 24.4 21.3 21.5 23.9 25.6 17.1 17.9 25.3 25.6 20.2 16.1 25.5 17.5 22.2 25.0 29.8 24.8 28.4 23.8 22.1 21.4 28.6 26.7 21.3 14.9 23.9 25.3 19.9 30.5 24.7 15.0 22.9 30.4 30.1 12.7 19.1 43.0 26.0 25.5 24.6 23.7 30.9 14.3 18.6 23.8 22.6 33.4 13.2 8.8 21.9 21.6 33.7 33.0 15.8 13.4 17.4 13.0 16.6 10.8 12.5 9.7 16.5 18.2 22.5 29.0 15.1 20.8 12.5 29.3 9.0 22.1 21.1 16.4 23.7 22.2 19.2 25.3 23.3 10.7 30.5 20.4 18.6 16.6 28.8 24.2 18.6 11.5 10.1 19.7 11.5 40.3 11.6 12.9 18.5 10.6 28.0 33.6 14.2 16.8 14.6 23.3 13.1 18.0 22.0 30.2 19.9 17.1 8.5 21.4 16.5 23.8 22.6 19.2 17.6 28.8 17.9 5.7 7.7 11.8 6.5 9.2 6.9 10.0 5.4 4.9 6.2 11.3 4.3 5.3 11.6 6.2 12.4 6.3 6.1 3.7 18.4 25.7 24.4 21.3 17.5 22.2 23.8 22.1 23.9 19.1 24.6 33.4 21.0 44.8 22.2 56.2 40.4 9.3 15.6 18.8 14.2 25.1 19.0 12.6 20.1 18.6 31.3 27.6 47.9 16.5 30.1 29.3 5.9 21.3 28.2 31.7 23.2 17.6 20.0 22.3 62.9 16.9 10.1 19.3 37.2 33.6 27.3 31.9 21.8 23.5 20.1 16.8 68.1 31.2 26.4 43.3 23.5 33.2 17.7 40.4 14.2 74.9 88.1 14.0 50.4 68.3 121.4 17.7 24.0 13.9 21.4 19.3 30.8 14.9 53.6 21.7 6.6 24.8 16.3 51.7 31.6 20.1 11.1 9.3 29.5 24.4 27.3 22.2 SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 980.5" "Cell type enriched" "Detected in some" 14 "Intestinal goblet cells: 8017.1" "Group enriched" "Detected in many" 20 "colorectal cancer: 237.5;pancreatic cancer: 269.7;stomach cancer: 111.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Group enriched" "Detected in some" 12 "HMC-1: 175.7;OE19: 480.7" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in single" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: AB_1080083" "unprognostic (3.49e-2)" "unprognostic (2.32e-1)" "prognostic favorable (8.85e-5)" "unprognostic (3.09e-4)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.66e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.42e-3)" 1.4 0.6 0.0 84.2 0.0 0.6 0.1 0.7 0.3 0.0 0.1 639.5 263.4 1.8 0.0 0.1 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.1 0.1 0.0 0.9 2.1 0.9 0.0 0.1 0.0 980.5 92.1 0.1 0.5 0.2 0.1 638.1 42.2 0.0 0.2 1.4 0.3 0.0 0.1 0.0 0.0 0.0 17.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 11.7 27.8 1.1 0.0 0.0 175.7 0.0 0.0 0.0 0.4 0.5 0.0 0.1 4.1 0.3 0.0 3.9 0.4 2.3 0.0 480.7 0.4 0.0 0.0 0.2 0.0 0.5 0.4 1.4 15.2 3.1 0.0 0.1 14.2 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.3 0.1 1.4 0.3 0.0 1.8 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.3 0.0 0.0 0.0 21.7 0.1 0.0 0.0 0.0 0.0 5.5 12.5 0.1 0.0 56.5 0.0 0.2 1.0 0.1 0.0 0.6 88.2 0.0 0.0 0.0 0.0 0.0 43.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8017.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.9 0.0 0.5 0.1 0.1 106.8 0.0 0.1 0.2 541.4 0.0 0.0 129.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.1 191.5 0.2 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SPIRE2 "KIAA1832, spir-2" ENSG00000204991 "Spire type actin nucleation factor 2" Q8WWL2 16 89818179-89871319 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.9;Gastric mucus-secreting cells: 46.9;Intestinal goblet cells: 43.8;Paneth cells: 39.9;Syncytiotrophoblasts: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 29.5;T-47d: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041413, HPA049415" Uncertain Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "Vesicles, Intermediate filaments" "HPA041413: AB_2677464, HPA049415: AB_2680755" "unprognostic (2.92e-1)" "unprognostic (1.39e-1)" "unprognostic (6.07e-3)" "unprognostic (6.96e-2)" "unprognostic (7.40e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (9.77e-5)" "unprognostic (2.10e-1)" "unprognostic (7.75e-2)" "unprognostic (5.34e-2)" "unprognostic (1.08e-2)" "unprognostic (6.95e-3)" "unprognostic (7.21e-3)" "unprognostic (6.65e-2)" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.59e-2)" 1.6 2.1 8.8 1.2 9.0 1.2 1.9 12.5 12.3 2.5 3.8 15.7 7.8 1.7 1.8 2.9 6.1 2.0 0.9 9.1 7.6 4.5 6.5 2.3 0.5 9.8 7.9 1.8 2.2 3.6 21.5 4.5 10.4 4.7 8.2 3.1 2.5 3.1 0.6 2.0 9.2 1.0 5.5 1.0 14.4 5.0 7.5 0.4 6.9 0.0 0.4 6.1 2.2 8.5 0.4 8.4 5.2 4.2 1.4 0.9 17.5 2.7 1.6 3.9 1.6 3.2 9.0 5.8 1.2 0.8 4.0 9.0 2.2 0.3 1.1 2.2 10.1 1.3 7.1 8.9 1.4 0.3 1.8 1.8 2.0 1.2 1.0 0.5 0.2 0.5 9.2 1.4 1.1 12.8 0.1 2.2 5.7 29.5 5.3 4.6 1.9 1.3 2.0 8.6 13.6 7.0 11.6 5.0 5.1 4.4 18.8 3.0 0.4 2.3 4.9 3.3 2.5 0.7 3.7 0.5 3.5 2.1 4.9 2.4 0.5 0.3 0.4 0.3 0.2 0.4 0.3 0.2 0.1 0.7 0.4 0.4 2.0 0.5 0.5 0.6 0.2 0.3 8.8 9.0 12.5 12.3 9.1 7.6 9.8 7.9 10.4 5.5 7.5 8.5 0.7 6.4 4.8 10.7 0.6 0.9 5.1 1.7 2.2 13.0 4.3 2.8 2.4 14.3 2.4 12.9 4.2 15.7 2.1 54.9 3.9 1.5 3.1 11.9 2.6 1.1 15.7 0.0 20.2 0.4 3.6 1.4 46.9 3.2 0.0 4.2 0.0 2.4 2.7 23.5 23.6 43.8 2.0 1.0 1.1 2.5 0.9 1.4 0.0 1.9 0.2 2.8 1.0 7.1 4.1 1.5 39.9 1.9 0.7 5.0 29.8 0.8 13.5 10.7 0.0 2.8 1.6 6.0 8.8 3.8 0.6 70.5 1.3 5.7 33.5 30.2 SPNS1 "HSpin1, LAT, nrs, PP2030, SLC62A1, SPIN1, SPINL" ENSG00000169682 "Sphingolipid transporter 1 (putative)" Q9H2V7 16 28974221-28984548 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041995, HPA042988" Enhanced Approved "Nucleoli fibrillar center,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA041995: AB_10959609, HPA042988: AB_10964587" "unprognostic (3.54e-2)" "unprognostic (4.57e-4)" "unprognostic (2.15e-1)" "unprognostic (2.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.66e-1)" "unprognostic (7.86e-5)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (1.27e-1)" "unprognostic (4.12e-2)" "unprognostic (3.02e-3)" "unprognostic (8.85e-7)" "unprognostic (1.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.26e-3)" "unprognostic (1.12e-2)" 26.8 30.8 17.0 19.3 17.4 37.0 24.8 17.1 26.3 27.7 18.6 32.5 22.4 30.9 6.6 25.9 23.0 18.0 27.5 16.9 15.7 32.1 33.9 31.5 20.1 19.1 16.6 22.0 24.4 20.8 21.1 19.8 17.2 26.5 10.0 6.5 24.4 14.9 25.0 35.7 27.8 15.1 15.8 33.9 28.2 20.3 19.8 20.8 27.8 14.9 10.5 30.5 25.2 18.3 25.9 59.6 22.2 51.9 41.5 22.8 62.9 28.2 28.9 46.1 40.9 55.0 60.4 16.4 67.8 25.5 38.2 53.3 36.4 31.2 16.4 19.0 61.6 23.8 57.1 69.3 70.4 26.7 49.2 38.4 40.9 49.7 21.0 26.8 42.9 30.0 54.4 28.7 23.4 68.8 29.3 75.8 52.6 20.8 39.1 36.7 26.7 73.6 24.9 24.8 39.5 51.3 20.1 59.3 44.9 18.5 59.2 31.9 36.6 37.3 28.2 52.7 22.0 43.2 36.7 15.6 47.7 40.4 30.8 13.4 32.8 13.5 9.9 42.1 8.3 5.7 9.8 13.0 27.6 4.3 10.0 6.8 5.6 7.7 28.8 11.5 12.1 18.1 17.0 17.4 17.1 26.3 16.9 15.7 19.1 16.6 17.2 15.8 19.8 18.3 24.4 6.4 7.2 8.8 14.9 21.3 21.3 29.8 14.8 31.0 17.2 15.7 0.3 20.0 20.1 20.2 29.2 63.3 26.5 10.5 13.7 58.1 2.1 15.3 19.2 24.1 12.2 21.8 10.2 45.7 72.3 24.6 16.8 18.9 22.7 40.9 19.2 14.3 98.7 26.9 10.3 13.8 46.8 45.6 28.4 3.7 22.7 61.8 33.8 15.0 32.7 28.5 24.7 7.1 8.6 37.3 16.0 16.6 18.6 14.4 41.5 18.2 26.2 38.6 6.6 17.4 23.8 24.8 33.5 16.4 22.7 87.3 20.7 37.8 20.0 19.4 SPOCD1 "FLJ25348, PPP1R146" ENSG00000134668 "SPOC domain containing 1" Q6ZMY3 1 31790422-31816051 "Predicted intracellular proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 9.7;urinary bladder: 9.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 13.2;Pancreatic endocrine cells: 30.9;Smooth muscle cells: 10.4;Spermatogonia: 13.1;Urothelial cells: 48.6" "Group enriched" "Detected in many" 7 "glioma: 13.9;urothelial cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 49.9;hTEC/SVTERT24-B: 51.5;RT4: 89.2;TIME: 46.2;U-87 MG: 84.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031713, HPA031714, HPA031715" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Nucleoplasm, Nucleoli" "HPA031713: AB_10604099, HPA031714: AB_2674007, HPA031715: AB_2674008" "unprognostic (7.78e-2)" "unprognostic (2.58e-2)" "unprognostic (1.85e-3)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (2.15e-3)" "unprognostic (2.60e-2)" "unprognostic (3.51e-1)" "unprognostic (2.18e-1)" "unprognostic (3.01e-2)" "unprognostic (3.00e-1)" "unprognostic (0.00e+0)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-2)" "prognostic favorable (4.05e-5)" 3.0 0.4 1.1 3.1 1.8 0.1 1.6 1.1 4.0 3.0 2.5 0.4 0.9 2.2 0.3 0.3 1.1 0.9 0.2 1.2 1.8 0.5 0.1 7.3 0.1 7.6 2.9 0.3 0.0 0.0 1.5 0.3 4.2 1.6 0.5 0.0 0.3 0.1 0.1 0.3 0.9 1.4 1.6 1.9 0.9 9.7 11.8 0.2 0.3 0.0 0.0 9.5 0.9 3.1 29.8 0.8 0.1 0.1 0.5 4.0 1.4 37.7 49.9 35.8 23.7 0.5 1.7 0.5 5.0 42.7 14.7 3.9 0.0 0.7 11.2 0.1 0.1 0.0 5.8 0.2 1.7 0.0 0.6 17.7 0.6 51.5 1.7 28.9 24.4 2.0 0.7 0.6 21.5 0.1 0.2 0.0 0.7 0.4 0.8 0.0 3.8 0.0 0.1 89.2 0.0 0.0 0.9 0.2 2.6 1.2 21.6 0.0 46.2 37.4 3.9 24.6 14.3 0.2 0.3 0.1 84.6 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.1 1.1 1.8 1.1 4.0 1.2 1.8 7.6 2.9 4.2 1.6 11.8 3.1 0.2 0.0 3.7 0.3 0.0 0.1 6.5 4.5 0.0 0.0 0.3 0.1 0.5 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.3 1.7 0.6 2.3 1.8 0.0 0.4 9.8 0.6 1.0 0.0 5.9 1.3 0.2 0.4 0.0 13.2 0.0 0.1 0.0 0.0 0.6 0.2 0.5 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 1.6 30.9 0.0 0.4 0.1 2.5 0.0 0.1 0.3 0.0 0.0 5.1 10.4 0.0 13.1 0.0 0.0 0.3 0.4 0.1 0.0 48.6 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2355095 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 109.1;Late spermatids: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: AB_325074, HPA039292: AB_2676429" "unprognostic (4.16e-2)" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "prognostic favorable (5.00e-5)" "unprognostic (2.34e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-1)" "unprognostic (7.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-3)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (3.40e-2)" 23.1 23.2 13.7 16.7 13.6 29.1 27.4 15.5 18.6 28.4 17.4 43.4 41.6 26.4 4.4 22.5 34.0 10.7 21.6 11.8 12.1 35.9 33.0 22.2 20.7 19.2 15.6 27.2 50.7 11.0 63.8 10.4 15.5 32.5 9.2 7.1 27.2 9.8 25.3 28.9 52.6 5.9 13.2 39.1 33.9 63.5 15.1 12.0 40.5 3.1 9.9 21.9 20.9 16.4 16.6 25.9 10.9 19.5 8.8 8.9 27.8 21.1 6.1 7.6 8.1 18.2 18.4 15.7 19.4 9.9 7.1 21.7 3.6 7.3 2.3 18.4 16.0 10.4 44.7 24.9 16.5 18.6 13.1 13.1 8.2 7.2 5.2 11.9 10.7 32.2 17.3 39.0 4.7 18.4 20.2 23.6 20.4 14.7 10.5 33.4 5.8 43.9 8.3 41.0 19.4 18.3 21.2 12.8 16.7 7.1 21.3 30.8 24.3 13.8 9.7 35.3 16.9 51.0 20.1 16.7 17.3 21.4 24.5 11.5 7.7 7.4 6.2 7.7 4.4 8.2 5.6 6.0 9.4 12.5 6.9 7.7 3.3 6.4 5.4 17.0 6.0 6.4 13.7 13.6 15.5 18.6 11.8 12.1 19.2 15.6 15.5 13.2 15.1 16.4 23.6 3.2 17.2 57.1 30.8 0.0 6.5 0.0 8.0 26.1 21.6 21.5 6.0 20.0 5.0 25.8 47.9 50.6 18.8 79.5 1.9 16.6 51.4 39.3 22.2 14.4 40.7 14.5 25.3 11.5 20.8 14.2 109.1 25.5 7.0 39.9 13.2 15.1 11.8 32.0 30.3 63.2 0.0 9.4 0.0 107.7 14.9 10.8 0.0 9.4 8.0 13.2 19.6 39.7 35.2 10.4 49.9 15.8 11.5 7.3 57.8 7.9 10.9 39.4 0.0 15.0 11.7 57.0 13.5 10.8 0.0 42.8 11.0 36.4 49.8 6.0 SPRR4 ENSG00000184148 "Small proline rich protein 4" Q96PI1 1 152970648-152972574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 145.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 54.2" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 17.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055963 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA055963: AB_2682988" "unprognostic (4.40e-2)" "unprognostic (7.38e-3)" "unprognostic (1.45e-1)" "unprognostic (6.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 145.4 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.9 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140558252 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA044598: AB_2679013, HPA050153: AB_2681033" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (8.69e-2)" "prognostic favorable (8.01e-6)" "unprognostic (9.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.90e-1)" "unprognostic (2.43e-1)" "unprognostic (9.38e-2)" "unprognostic (7.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.61e-1)" "unprognostic (5.34e-2)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-1)" 12.2 34.0 8.7 7.7 9.0 9.6 9.7 15.8 12.3 10.0 9.2 12.5 5.1 8.2 6.0 9.3 9.4 5.6 12.0 9.9 9.3 12.4 25.8 15.0 6.3 8.4 8.2 14.9 7.5 4.7 22.2 5.8 8.8 12.5 4.7 7.2 14.8 6.2 14.5 9.4 11.9 5.4 8.6 17.6 14.0 22.6 8.9 5.6 12.9 2.5 5.2 9.4 8.8 9.2 9.7 22.7 11.8 12.3 5.6 7.6 16.4 16.1 9.1 10.3 10.8 41.8 5.9 8.2 11.7 6.2 5.5 6.4 2.1 12.0 4.1 12.7 13.9 7.2 25.0 16.1 12.0 13.1 9.4 14.7 6.1 5.5 2.8 9.1 4.7 13.8 7.4 12.1 6.9 29.5 10.7 20.4 3.6 5.2 18.0 11.7 10.0 7.9 5.4 11.3 8.3 9.8 9.4 8.5 11.6 4.1 10.5 14.7 7.5 9.7 5.1 8.5 13.2 15.1 10.9 8.6 12.0 16.8 6.5 16.1 26.0 20.3 10.7 23.8 9.9 15.8 10.2 10.4 25.2 14.0 8.2 9.4 43.0 13.6 23.6 15.2 19.5 26.8 8.7 9.0 15.8 12.3 9.9 9.3 8.4 8.2 8.8 8.6 8.9 9.2 43.3 6.4 49.4 13.4 46.7 52.4 68.5 126.1 38.7 23.6 57.8 48.9 71.7 57.2 86.4 33.1 8.4 103.7 56.9 87.8 113.5 102.7 104.6 59.5 33.4 39.8 38.4 35.1 15.5 148.2 117.9 48.6 64.7 43.1 68.4 21.8 42.1 69.7 93.1 15.2 17.2 71.6 107.8 61.2 71.5 150.0 25.1 82.0 67.6 7.5 90.4 59.5 42.2 9.0 11.5 186.0 78.7 29.7 113.7 82.9 83.7 131.0 84.1 23.7 26.3 26.7 76.1 77.2 30.7 62.3 45.9 179.0 47.4 66.8 49.2 142.6 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 SRCAP "DOMO1, EAF1, KIAA0309, SWR1" ENSG00000080603 "Snf2 related CREBBP activator protein" Q6ZRS2 16 30698209-30741409 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 186.4;Club cells: 145.6;Ionocytes: 179.0;Respiratory ciliated cells: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028929 Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA028929: AB_10601265" "unprognostic (1.26e-1)" "unprognostic (1.35e-1)" "unprognostic (5.07e-1)" "unprognostic (6.57e-2)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (8.59e-2)" "unprognostic (2.34e-2)" "unprognostic (3.77e-1)" "unprognostic (6.45e-2)" "unprognostic (4.36e-2)" "unprognostic (8.57e-2)" "unprognostic (1.16e-2)" "unprognostic (2.09e-1)" "unprognostic (4.11e-2)" "unprognostic (7.71e-2)" "unprognostic (1.07e-1)" 15.4 11.9 3.6 18.9 4.8 30.1 10.1 7.1 4.2 12.8 1.7 13.2 15.7 15.5 6.4 13.5 14.2 10.9 12.1 2.9 3.4 9.6 7.1 11.6 15.3 5.9 4.3 16.9 19.4 20.2 9.5 12.6 3.5 12.6 11.2 12.5 18.0 13.1 24.5 16.2 16.1 15.0 0.8 18.7 16.0 20.6 7.7 20.2 14.0 19.4 13.6 11.3 9.9 6.8 29.5 60.1 36.9 35.9 28.3 19.5 37.7 24.0 21.1 26.2 20.7 27.8 21.9 65.9 29.7 30.5 16.9 27.8 37.7 27.5 21.9 42.2 88.1 42.5 56.2 24.3 11.4 49.8 48.0 20.8 13.2 40.3 29.0 12.8 27.8 21.7 65.4 36.5 19.7 34.5 42.2 17.4 37.6 10.8 27.7 57.7 28.7 36.4 7.5 34.2 34.5 36.5 26.6 31.0 8.4 12.2 35.4 26.0 44.1 37.0 26.5 21.0 31.6 39.8 36.7 45.9 29.7 23.2 28.9 0.3 0.7 2.9 0.8 1.2 0.6 0.7 0.4 0.9 0.5 1.0 0.5 0.4 2.2 0.6 0.3 0.9 0.9 0.7 3.6 4.8 7.1 4.2 2.9 3.4 5.9 4.3 3.5 0.8 7.7 6.8 3.0 3.2 3.7 8.8 9.8 24.6 1.9 186.4 13.1 7.5 3.3 1.8 2.4 4.3 145.6 1.8 8.4 2.3 5.3 54.3 0.0 1.4 1.2 4.6 3.0 3.4 11.3 7.6 8.6 3.1 1.4 4.2 19.9 4.7 2.5 3.0 2.2 3.0 2.3 8.4 8.6 17.7 179.0 1.9 14.3 0.9 2.8 3.4 10.6 8.4 3.0 1.7 6.2 4.5 10.6 1.9 39.1 1.2 11.1 3.1 3.1 0.6 118.3 5.8 0.0 5.0 14.3 5.6 6.0 7.8 58.2 2.5 8.9 2.0 25.6 3.1 SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837011 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 219.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "RPMI-8226: 202.5;SK-BR-3: 178.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005406, HPA043343, HPA043878" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB005406: AB_2194226, HPA043343: AB_2678439, HPA043878: AB_2678710" "unprognostic (9.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "prognostic favorable (2.66e-4)" "unprognostic (4.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (3.14e-2)" "unprognostic (9.02e-3)" "prognostic favorable (9.05e-4)" "unprognostic (3.12e-1)" "unprognostic (9.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-3)" 42.2 219.2 26.8 7.9 41.5 20.1 46.5 20.4 37.2 51.5 9.4 37.7 28.7 23.4 8.9 68.7 42.7 14.0 27.4 20.0 25.9 24.7 128.5 26.4 9.1 30.1 29.7 41.4 17.0 8.4 37.0 7.8 24.2 37.2 6.7 3.9 89.5 16.7 34.5 47.8 34.0 5.6 23.4 17.2 25.2 35.4 35.8 14.4 27.0 2.9 6.3 32.5 48.8 41.7 54.1 122.5 12.0 85.2 24.9 55.8 23.5 18.5 60.0 16.4 39.2 23.3 104.2 33.5 17.2 14.8 14.5 144.0 16.7 47.2 4.0 21.1 7.2 16.8 86.4 19.1 36.1 2.5 29.6 42.0 19.6 21.8 12.5 12.2 17.6 64.9 36.8 105.8 2.5 118.7 46.9 26.1 17.8 38.3 23.1 32.6 10.8 202.5 9.0 23.1 16.3 70.5 24.4 178.7 48.0 8.9 62.0 32.6 21.5 8.2 40.5 19.5 12.5 32.2 3.1 15.5 48.9 24.6 45.2 0.0 0.3 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.6 1.3 0.1 0.1 0.1 0.0 0.2 26.8 41.5 20.4 37.2 20.0 25.9 30.1 29.7 24.2 23.4 35.8 41.7 6.1 6.4 26.0 66.9 11.9 9.3 12.0 29.2 14.8 24.5 58.0 30.6 9.4 18.6 29.7 20.2 29.2 4.5 11.4 44.5 1.9 16.5 2.7 30.9 37.2 10.5 29.9 24.8 12.8 23.5 15.7 24.7 31.1 31.9 14.7 13.2 12.8 72.2 12.1 58.9 11.3 30.8 24.4 14.0 13.3 4.9 29.8 15.1 8.8 15.0 11.0 51.7 1.0 10.6 56.7 16.7 20.8 10.9 8.4 19.0 33.2 6.6 32.1 31.6 13.1 15.6 12.9 11.4 4.9 40.2 18.3 19.8 13.4 27.5 41.1 25.2 SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" 22.8 80.7 50.1 31.1 58.7 32.3 24.5 22.3 60.5 26.5 2.5 47.1 40.8 34.4 60.5 82.0 27.4 25.3 53.8 51.8 32.3 33.3 36.2 43.2 35.2 38.5 37.8 35.8 45.8 51.4 30.5 24.5 38.3 33.5 31.6 21.0 49.1 22.9 34.1 58.4 35.9 30.1 16.1 26.1 53.8 20.4 37.8 25.0 23.3 33.5 36.2 29.7 39.0 45.1 65.5 45.8 119.4 111.6 68.4 90.9 66.7 21.4 71.1 24.8 50.5 54.3 84.2 115.8 29.7 52.6 91.1 109.6 68.7 141.8 17.5 32.9 75.0 58.0 79.7 54.6 113.8 85.7 37.9 85.8 78.7 65.1 80.6 56.7 49.2 64.2 60.6 135.9 26.4 83.1 62.5 64.5 75.7 81.2 34.9 71.3 68.1 189.0 103.3 67.6 48.2 36.3 49.1 89.3 91.7 69.5 56.3 150.2 53.0 33.2 61.0 15.9 25.8 98.3 54.3 91.7 32.4 64.0 51.9 0.0 4.7 1.6 4.6 3.6 3.1 7.0 2.5 3.3 5.0 4.8 2.2 2.6 0.7 1.4 3.1 6.3 1.5 4.8 50.1 58.7 22.3 60.5 51.8 32.3 38.5 37.8 38.3 16.1 37.8 45.1 14.5 44.8 43.3 100.6 35.4 16.3 13.5 52.2 30.7 41.0 36.3 23.1 30.3 37.1 38.0 58.8 10.4 25.4 23.5 67.0 3.9 20.3 15.9 25.2 10.5 16.8 49.1 14.1 72.6 44.3 22.6 16.3 42.8 59.2 12.7 43.2 8.2 34.3 14.8 57.2 75.1 39.4 52.9 10.3 14.8 7.0 31.4 16.3 7.2 67.5 18.1 18.6 20.6 90.5 129.5 38.4 30.5 27.4 29.2 27.9 26.3 4.8 30.0 18.7 19.7 13.7 20.5 8.4 13.8 55.7 28.1 36.5 19.0 43.0 40.3 30.2 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.6" "Cell type enriched" "Detected in single" 4 "Gastric mucus-secreting cells: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;MCF7: 3.0;OE19: 4.4;RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.0 0.0 0.1 0.2 0.1 0.1 0.4 0.6 0.2 0.0 0.0 0.7 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.0 0.4 0.2 0.0 0.1 0.9 1.6 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.0 4.4 0.4 0.0 0.1 0.0 0.0 6.0 0.4 0.5 0.1 1.2 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 379.9;Late spermatids: 599.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 61.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 8.7 6.0 6.4 18.1 8.2 41.7 14.5 10.0 14.8 12.5 6.8 31.2 25.2 12.7 9.3 23.9 8.6 11.9 8.3 8.9 3.7 16.7 16.0 12.9 19.7 4.0 4.1 8.7 23.3 14.5 9.0 14.5 4.3 9.6 35.6 25.8 16.1 10.9 20.0 26.7 23.6 14.2 2.4 17.8 18.0 44.7 5.2 19.9 8.7 12.6 24.3 31.0 16.2 11.6 104.1 39.2 54.9 82.4 30.2 39.3 69.0 62.1 60.1 57.3 60.2 109.0 34.1 139.0 51.8 39.1 65.5 51.3 110.3 74.2 100.6 96.2 79.9 73.5 42.6 93.8 26.7 111.3 34.0 25.6 39.3 66.0 84.7 44.6 72.3 76.4 157.7 55.6 48.2 36.8 111.1 80.8 45.9 62.9 42.7 77.8 67.3 84.1 56.8 169.5 117.5 42.9 65.4 59.3 42.5 55.2 33.3 70.3 54.8 52.4 41.3 37.2 78.6 33.1 78.6 128.5 20.9 124.3 48.1 61.0 4.4 30.6 8.5 5.3 12.1 8.6 11.2 11.5 5.9 6.9 9.2 10.0 50.9 11.2 7.6 3.3 14.9 6.3 6.4 8.2 10.0 14.8 8.9 3.7 4.0 4.1 4.3 2.4 5.2 11.6 26.6 9.6 25.8 18.6 40.0 42.3 119.3 91.0 67.7 36.8 25.8 22.7 28.7 14.3 51.4 22.0 37.5 54.3 33.1 51.6 29.4 55.4 379.9 29.9 40.2 29.2 46.2 46.7 74.2 68.2 53.2 25.1 46.9 54.0 7.6 44.1 13.2 41.8 21.6 10.1 50.0 50.8 32.6 16.3 19.9 599.1 22.1 20.0 16.0 24.4 31.5 16.8 32.0 30.2 29.7 100.4 47.9 24.8 68.0 117.9 50.8 59.4 33.8 92.9 6.6 17.8 48.9 197.3 100.4 126.8 41.8 39.7 43.6 33.7 90.7 162.6 SRRM3 FLJ37078 ENSG00000177679 "Serine/arginine repetitive matrix 3" 7 76201896-76287288 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 56.0;retina: 27.2" "Group enriched" "Detected in many" 7 "Bipolar cells: 153.1;Cone photoreceptor cells: 479.6;Excitatory neurons: 139.1;Horizontal cells: 171.6;Inhibitory neurons: 144.4;Rod photoreceptor cells: 421.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SCLC-21H: 10.9;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019337 Approved "Plasma membrane,Intermediate filaments,Microtubules" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Intermediate filaments, Microtubules" "HPA019337: AB_1848909" "unprognostic (1.65e-1)" "unprognostic (1.96e-1)" "unprognostic (8.37e-3)" "unprognostic (4.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (6.51e-2)" "unprognostic (1.89e-3)" "unprognostic (1.62e-2)" "unprognostic (5.07e-3)" "unprognostic (6.37e-2)" "unprognostic (3.73e-3)" "unprognostic (5.05e-1)" "unprognostic (2.98e-1)" "unprognostic (1.84e-1)" "unprognostic (5.15e-2)" 0.0 2.1 6.0 0.1 13.2 0.0 0.0 56.0 30.7 0.1 0.0 0.3 0.1 0.2 0.2 0.1 0.0 0.0 0.1 4.8 0.2 0.0 0.0 0.0 0.0 41.5 3.2 0.2 0.3 0.3 8.9 0.0 40.1 0.1 0.1 27.2 0.1 0.0 0.1 0.0 0.1 0.0 1.6 0.0 0.4 2.1 0.9 0.0 0.0 0.0 0.0 0.0 0.2 4.7 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 8.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 13.2 56.0 30.7 4.8 0.2 41.5 3.2 40.1 1.6 0.9 4.7 0.3 0.0 0.0 8.1 0.0 2.0 6.4 1.9 7.4 153.1 1.8 0.5 6.9 1.5 1.2 0.0 479.6 0.4 0.0 0.2 0.0 2.0 22.2 0.5 4.2 1.2 12.1 0.0 139.1 2.4 8.1 4.8 0.5 1.0 0.0 12.0 1.8 0.0 0.5 171.6 144.4 0.1 2.0 0.0 0.8 32.2 2.1 0.2 3.6 5.6 0.0 15.9 0.0 18.6 4.9 0.9 0.1 2.2 0.0 2.2 0.0 0.4 0.2 421.8 0.0 1.2 2.0 8.6 3.1 4.9 1.1 2.2 0.1 0.2 0.0 4.9 SRSF5 "HRS, SFRS5, SRP40" ENSG00000100650 "Serine and arginine rich splicing factor 5" Q13243 14 69726900-69772005 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043484, HPA056523" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 23000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "HPA043484: AB_10797143, HPA056523: AB_2683164" "unprognostic (2.08e-3)" "prognostic favorable (7.91e-4)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.30e-3)" "unprognostic (1.07e-3)" "unprognostic (2.37e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.42e-1)" "unprognostic (1.00e-2)" 210.9 188.4 68.1 149.5 72.5 456.9 229.8 60.3 108.2 174.2 125.9 231.8 129.2 222.5 218.0 217.9 240.9 130.1 154.4 75.9 69.7 119.6 183.8 214.8 210.1 75.5 71.1 220.0 136.6 188.1 215.5 105.1 74.1 172.7 164.8 233.8 235.8 126.7 217.6 282.0 256.6 180.3 66.0 211.8 212.8 104.1 69.5 214.7 224.8 68.3 155.0 189.3 177.4 97.1 456.4 133.5 313.8 141.4 192.7 179.6 177.4 214.6 239.7 177.6 183.7 164.7 283.6 473.1 110.4 301.8 174.7 210.2 242.5 309.2 209.7 407.4 142.3 354.3 386.7 183.6 224.3 334.7 255.7 350.9 201.2 199.7 216.3 260.4 247.0 401.8 255.4 268.3 114.3 382.1 385.1 232.4 182.0 356.6 128.2 324.0 148.5 183.3 237.2 563.1 165.9 236.3 364.3 214.1 296.0 188.5 235.9 292.3 299.7 98.4 264.2 110.9 205.6 261.6 184.5 754.8 232.3 286.1 140.1 137.1 65.8 103.6 93.1 117.9 94.9 109.5 83.1 85.0 70.1 108.7 81.1 79.6 161.9 86.2 129.6 99.8 74.8 77.2 68.1 72.5 60.3 108.2 75.9 69.7 75.5 71.1 74.1 66.0 69.5 97.1 380.7 253.2 309.1 218.1 392.8 138.0 768.6 610.1 204.9 387.4 248.6 259.1 195.0 240.2 386.6 183.9 239.8 444.3 542.9 471.8 320.8 201.7 190.3 224.2 169.8 293.6 302.9 195.4 199.5 171.8 261.5 288.0 188.6 225.3 480.2 251.3 249.9 225.4 217.7 378.6 177.7 376.6 380.5 236.2 154.3 105.0 345.5 314.7 133.4 104.9 323.4 277.4 428.5 128.2 268.7 226.6 538.5 267.1 212.3 376.7 484.7 228.2 373.4 317.3 276.1 583.7 354.2 201.8 149.8 196.4 145.6 749.2 456.6 201.6 275.5 542.1 SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047377 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: AB_2680020" "unprognostic (4.09e-3)" "unprognostic (1.90e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "prognostic favorable (7.03e-4)" "unprognostic (6.55e-2)" "unprognostic (4.51e-2)" "unprognostic (2.62e-2)" "unprognostic (2.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (2.24e-3)" 21.0 17.1 27.6 18.5 28.6 33.9 21.9 28.8 37.1 19.8 26.7 17.5 19.0 12.6 17.8 21.2 15.7 10.4 18.7 28.2 28.4 24.5 32.4 19.6 35.4 28.2 27.8 19.1 21.6 13.5 25.1 9.9 28.3 35.9 13.6 13.7 19.1 8.6 16.2 24.9 25.6 7.4 28.4 31.6 22.7 10.1 27.8 23.6 20.4 11.0 30.2 19.4 18.5 31.5 32.3 14.0 29.0 26.4 34.9 27.8 17.3 20.6 22.4 28.7 32.2 27.1 29.1 43.3 18.2 13.6 31.6 17.9 33.9 28.0 30.9 21.7 40.5 46.9 28.9 45.3 25.4 62.5 36.2 22.1 17.7 23.7 21.9 20.6 31.4 39.1 43.2 65.4 23.1 29.3 44.8 76.4 45.9 42.7 34.2 23.6 20.6 61.2 32.3 38.2 16.2 23.0 17.6 27.2 29.8 30.2 35.8 57.4 19.5 18.0 29.0 42.8 38.0 46.5 76.3 73.5 26.3 66.1 17.0 60.4 56.4 84.9 88.4 66.0 121.0 120.3 116.3 106.2 62.1 104.3 99.5 101.1 75.8 83.0 50.9 74.5 139.2 90.4 27.6 28.6 28.8 37.1 28.2 28.4 28.2 27.8 28.3 28.4 27.8 31.5 39.3 12.8 16.7 5.5 96.3 107.1 70.1 101.5 91.0 16.2 78.6 77.8 19.3 42.9 46.1 27.6 8.4 57.1 102.9 39.2 56.7 43.4 4.3 47.0 37.9 37.0 55.1 67.3 13.6 49.2 75.8 39.0 39.8 71.9 45.7 39.6 32.5 61.0 66.8 23.5 11.2 51.1 79.3 38.6 51.2 3.7 34.5 43.0 51.6 6.5 69.3 38.1 88.6 3.0 25.8 50.6 58.9 15.8 72.4 75.6 121.4 85.2 28.2 26.8 13.1 26.4 32.5 19.4 24.7 84.5 138.1 37.4 103.2 34.5 53.7 99.2 SSH1 "KIAA1298, SSH1L" ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778191-108857590 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 6.6 5.1 5.6 5.1 5.1 7.9 5.0 9.2 5.5 5.8 7.2 7.2 2.9 5.9 4.0 5.5 5.3 5.3 7.8 5.7 5.3 6.7 5.5 11.8 4.1 5.8 5.7 5.0 4.3 5.4 5.2 5.2 5.2 5.2 4.1 5.7 3.9 4.8 11.9 4.6 5.1 5.5 5.0 7.5 4.9 3.5 5.1 3.6 5.3 6.5 4.2 6.0 5.2 5.1 9.9 12.7 8.2 6.4 15.1 12.8 7.2 12.8 26.1 11.0 9.7 6.4 4.6 4.9 8.7 29.0 18.8 9.8 4.9 20.7 8.9 9.9 4.8 11.3 6.0 4.0 8.1 5.8 28.4 17.7 7.0 10.0 22.0 27.1 10.3 5.6 2.5 3.6 29.1 5.4 6.6 8.0 5.8 3.8 10.3 4.6 9.8 6.1 4.5 17.1 6.1 8.1 11.0 2.8 24.2 11.2 3.9 4.8 8.1 19.6 8.4 11.9 7.1 7.3 7.0 5.6 10.3 4.5 63.1 1.8 0.9 2.0 1.0 1.5 0.9 0.6 0.5 0.9 0.6 0.6 0.4 0.5 2.1 0.7 1.2 0.7 0.6 0.5 5.6 5.1 9.2 5.5 5.7 5.3 5.8 5.7 5.2 5.0 5.1 5.1 34.5 9.6 16.1 26.1 6.3 9.4 20.8 23.6 19.4 12.9 6.9 6.6 25.1 11.5 12.7 14.7 16.7 6.0 18.5 8.2 5.9 8.4 2.2 10.8 17.1 52.2 5.4 7.8 27.3 8.2 4.4 14.0 13.7 16.9 20.8 12.0 29.3 15.2 12.3 11.8 35.4 5.4 0.0 23.0 20.3 5.0 6.5 21.1 12.4 55.3 33.7 7.8 14.4 14.1 14.8 12.3 2.4 12.8 13.1 21.8 4.0 6.7 9.0 19.1 6.6 17.8 18.1 1.4 7.7 13.2 8.9 2.3 17.9 7.6 7.8 13.9 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303478-67312607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.6;eosinophil: 11.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.6" "Cell line enhanced" "Detected in many" "HaCaT: 64.9;MCF7: 64.1;RT4: 111.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 14.4 7.8 8.9 4.0 12.0 9.3 16.2 14.1 11.6 25.9 9.5 19.3 13.3 16.0 7.5 41.9 18.3 11.5 12.5 9.1 10.1 13.1 10.9 12.7 3.1 14.6 10.8 23.5 15.3 9.8 9.7 6.5 13.2 29.9 9.3 1.2 26.2 28.8 6.8 25.2 15.0 6.1 12.3 9.4 20.1 2.3 11.5 1.9 16.3 3.8 4.8 37.4 32.5 14.9 17.3 18.7 0.4 0.6 11.4 11.8 18.8 10.3 13.7 5.6 5.1 21.2 46.8 1.0 32.5 10.5 11.9 64.9 6.0 46.4 2.8 3.6 6.3 4.3 32.2 9.9 8.2 0.9 16.0 12.2 40.5 8.3 8.3 12.9 6.3 0.4 0.1 1.5 6.2 64.1 0.8 7.3 4.2 48.9 13.8 20.6 0.6 3.1 18.2 111.2 3.7 5.8 24.8 41.0 12.8 6.3 57.1 15.3 10.4 4.5 9.8 12.7 2.7 1.5 0.9 0.5 12.7 6.9 4.9 11.6 1.5 11.1 2.0 2.3 1.7 0.2 1.9 1.7 1.7 0.1 0.8 0.8 4.4 1.5 1.1 1.1 1.8 1.1 8.9 12.0 14.1 11.6 9.1 10.1 14.6 10.8 13.2 12.3 11.5 14.9 7.6 3.2 8.7 8.5 0.9 7.0 20.8 25.2 11.4 0.8 21.3 17.3 3.8 20.0 23.4 16.5 0.0 15.1 3.3 28.3 3.9 19.4 0.1 8.3 5.6 4.7 3.6 5.2 4.2 21.6 24.9 8.0 20.9 17.8 3.8 8.1 3.9 5.0 7.7 1.7 5.3 14.4 24.4 6.2 3.1 0.6 13.1 4.8 8.8 2.8 9.2 4.8 7.2 0.0 15.9 20.0 21.0 12.0 0.7 15.4 20.2 7.4 11.6 0.5 0.0 4.9 9.2 0.5 0.4 27.0 10.4 15.7 4.4 5.3 21.4 26.8 ST8SIA2 "HsT19690, SIAT8B, ST8SIA-II, STX" ENSG00000140557 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2" Q92186 15 92393881-92468728 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.4;heart muscle: 3.9" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.9;Cardiomyocytes: 4.3;Inhibitory neurons: 3.5;Muller glia cells: 2.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.8;LHCN-M2: 7.7;RH-30: 11.7;RPMI-8226: 8.9;SH-SY5Y: 5.0;WM-115: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA054518, HPA057819" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA054518: AB_2682514, HPA057819: " "unprognostic (4.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.26e-1)" "unprognostic (9.32e-3)" "unprognostic (1.03e-1)" "unprognostic (2.87e-2)" "unprognostic (2.32e-1)" "unprognostic (1.28e-5)" "unprognostic (3.91e-2)" "unprognostic (5.39e-3)" "unprognostic (1.59e-2)" "unprognostic (4.44e-3)" "unprognostic (4.78e-2)" "unprognostic (2.29e-1)" "unprognostic (3.16e-1)" "unprognostic (3.00e-1)" 0.0 0.3 0.6 0.0 0.6 0.0 0.4 0.6 2.2 0.8 0.0 0.1 0.0 0.4 0.8 0.0 0.0 0.2 3.9 1.5 1.2 0.1 0.0 0.0 0.0 8.4 1.9 0.0 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.4 1.8 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.2 25.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.2 0.0 4.1 0.0 0.0 0.0 11.7 8.9 0.0 0.0 0.6 5.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.2 0.3 0.0 0.2 0.9 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 2.2 1.5 1.2 8.4 1.9 8.2 0.1 0.4 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.9 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 1.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA002857: AB_1079861" "unprognostic (1.62e-1)" "unprognostic (1.01e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.70e-2)" "unprognostic (3.77e-2)" "unprognostic (9.67e-3)" "unprognostic (4.68e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.81e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.97e-1)" 27.9 22.9 20.7 34.2 26.3 72.8 41.5 32.6 24.1 33.3 30.4 28.8 23.8 35.7 28.3 26.8 30.1 25.2 21.5 18.0 22.6 33.7 28.5 28.6 45.0 26.2 21.9 46.0 31.7 51.9 12.0 35.8 27.8 29.8 28.2 45.5 26.5 29.6 23.3 26.1 26.5 25.8 24.2 37.4 28.5 8.0 21.2 81.4 49.3 36.0 44.3 28.4 17.6 39.6 62.6 56.9 84.5 53.0 34.9 52.3 54.4 58.0 61.8 58.5 73.2 53.8 65.1 115.0 79.6 52.3 65.5 55.6 173.6 48.8 82.5 81.9 74.7 106.6 110.8 35.7 35.6 140.7 80.0 42.2 46.4 69.5 111.4 50.2 49.7 114.2 105.4 118.9 43.1 67.8 180.6 62.9 44.5 55.8 84.4 125.9 112.0 96.1 44.9 117.3 75.7 60.6 131.2 47.7 66.9 59.2 28.9 62.2 61.5 0.3 31.1 69.4 66.6 50.9 82.2 141.6 36.8 84.3 60.3 28.2 15.2 28.0 15.0 18.9 17.8 15.0 15.6 14.6 19.1 19.0 21.3 17.5 44.5 18.8 23.1 16.5 13.5 10.0 20.7 26.3 32.6 24.1 18.0 22.6 26.2 21.9 27.8 24.2 21.2 39.6 71.1 64.1 56.6 42.4 80.9 56.2 61.5 31.5 72.3 51.0 58.0 48.4 44.9 37.1 50.6 44.1 60.5 32.2 113.4 42.9 21.5 42.3 1.1 65.1 70.4 62.3 58.1 77.0 41.8 38.2 32.7 64.5 39.8 79.3 58.1 53.6 59.3 42.2 36.0 45.4 51.9 35.0 28.5 71.4 65.0 4.2 65.9 89.9 33.8 70.3 91.4 61.2 97.9 69.4 114.0 54.9 29.3 69.2 73.8 81.4 28.0 35.7 51.4 62.9 65.7 104.0 60.3 14.8 15.4 51.0 56.1 71.4 87.2 49.5 38.9 83.6 STAM2 Hbp ENSG00000115145 "Signal transducing adaptor molecule 2" O75886 2 152116801-152175763 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035528, HPA035529" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA035528: AB_10601606, HPA035529: AB_10672868" "unprognostic (1.53e-1)" "unprognostic (1.79e-1)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (5.16e-2)" "unprognostic (2.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (7.92e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" 9.7 9.9 7.3 7.9 8.3 3.1 12.5 7.5 8.9 10.9 8.0 10.3 9.3 10.9 8.7 9.1 12.8 9.3 9.6 6.3 7.7 14.6 11.0 10.8 8.7 7.5 7.9 11.0 8.8 12.8 6.5 10.3 7.9 12.9 10.9 11.1 11.9 8.9 5.8 10.8 9.3 10.1 8.0 8.3 11.7 12.6 7.4 8.5 14.3 7.7 8.9 10.7 6.6 9.7 8.3 7.9 7.2 8.8 18.5 22.0 7.7 16.8 19.4 10.7 13.6 7.8 7.8 10.8 13.1 24.2 9.4 8.3 8.0 15.6 17.1 13.3 6.3 7.8 5.1 11.8 21.2 11.5 14.6 16.9 14.6 20.0 26.8 15.5 11.7 7.2 5.1 7.5 22.2 8.1 6.1 8.9 4.5 6.1 11.2 4.9 8.9 5.9 16.7 14.1 3.8 5.9 9.3 8.2 14.1 8.0 11.1 10.5 15.3 23.7 7.6 18.8 10.3 6.1 6.7 6.8 17.9 9.2 13.2 16.8 3.4 4.6 1.7 4.6 1.6 1.7 1.8 1.9 2.7 2.0 1.5 1.9 8.6 2.6 7.1 3.2 2.2 1.6 7.3 8.3 7.5 8.9 6.3 7.7 7.5 7.9 7.9 8.0 7.4 9.7 17.6 25.6 33.5 39.2 10.9 13.8 12.0 16.4 15.9 10.6 17.9 11.6 30.5 7.2 28.9 16.5 16.7 7.4 14.7 22.1 23.5 13.9 147.8 37.2 25.5 15.1 8.3 13.5 43.8 14.2 14.6 22.7 27.0 22.2 27.1 14.8 17.5 16.0 16.7 1.7 39.7 20.2 20.3 20.0 13.0 64.4 15.8 16.9 14.2 32.8 19.6 14.7 8.2 51.8 61.0 21.2 18.2 15.4 10.9 14.3 13.9 14.8 55.6 11.6 26.3 18.0 16.1 54.1 20.1 13.5 13.2 20.2 9.3 18.2 13.5 16.1 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 1108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: AB_2732470" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 15.6 11.6 21.7 14.6 30.6 13.3 20.2 29.7 23.8 19.3 19.3 21.5 20.7 20.6 15.5 25.4 18.3 16.9 22.3 20.6 24.5 21.9 19.0 15.7 19.3 31.3 28.0 17.7 12.2 24.3 9.3 17.3 30.4 22.1 23.2 14.6 21.5 15.6 37.4 16.7 20.4 21.3 27.9 14.9 18.2 15.8 27.1 23.2 22.6 42.8 21.6 16.8 16.0 38.6 39.0 44.0 34.0 31.6 31.1 37.2 39.1 23.3 31.7 42.1 40.3 73.7 35.9 32.2 35.8 19.8 55.7 30.0 36.6 81.7 47.6 56.6 41.3 43.3 29.1 58.1 43.4 35.8 50.0 30.1 57.6 49.6 70.7 53.5 25.1 43.7 47.9 47.8 1108.9 46.8 55.9 32.4 54.9 55.1 22.7 38.6 89.4 46.1 45.2 43.0 62.0 45.8 28.4 34.6 49.1 36.4 32.3 21.4 22.0 37.5 44.5 22.9 41.9 44.8 46.9 24.9 46.4 38.1 44.7 30.7 18.9 34.2 15.9 21.4 17.2 21.5 18.3 15.6 19.9 19.3 18.9 14.4 27.6 22.3 19.9 19.5 25.8 14.9 21.7 30.6 29.7 23.8 20.6 24.5 31.3 28.0 30.4 27.9 27.1 38.6 22.1 19.2 17.7 22.9 21.5 16.3 28.9 61.7 31.3 22.3 28.8 27.7 41.1 28.6 34.4 25.8 12.5 43.0 27.4 48.7 49.0 37.9 80.8 35.6 37.3 21.4 10.3 34.9 18.5 36.3 32.5 26.0 18.8 45.8 52.6 21.2 17.5 41.1 33.0 26.9 22.1 36.4 40.7 27.7 16.2 125.0 32.6 25.2 7.2 16.9 34.1 24.9 25.7 26.2 67.2 44.5 41.8 34.6 21.5 40.9 57.2 68.8 24.5 21.0 39.5 28.2 27.2 33.1 44.2 44.5 21.6 44.5 21.4 27.5 34.3 27.1 STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 260.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" 24.8 33.4 18.3 18.8 29.1 25.4 23.4 21.6 18.9 22.3 14.9 21.5 24.1 20.4 2.7 24.1 21.5 17.2 16.3 17.9 15.4 18.9 25.8 28.8 22.3 21.1 21.3 21.3 26.5 15.2 24.0 17.1 19.0 20.1 5.2 3.2 21.2 11.3 23.9 27.0 26.7 9.2 18.7 33.1 26.5 26.2 22.5 14.8 21.4 9.5 8.8 21.0 20.1 18.5 29.3 47.6 18.6 33.5 19.9 22.9 31.2 23.1 24.9 27.1 24.3 24.0 47.6 25.2 47.7 17.8 30.8 55.4 11.3 21.0 6.3 36.2 34.5 15.2 18.8 30.1 25.9 29.6 35.5 24.5 19.0 29.8 12.6 19.0 23.4 36.4 41.0 27.4 23.5 24.7 32.2 25.6 22.2 15.3 20.6 28.5 31.4 40.1 15.0 35.7 24.9 29.1 16.1 260.8 64.0 10.8 34.1 41.7 26.3 43.2 29.5 46.5 43.6 27.5 37.8 18.7 36.2 36.8 45.1 23.7 36.3 54.4 42.7 35.5 30.7 20.8 29.6 32.7 38.3 26.1 29.1 27.8 63.6 39.6 29.3 18.7 38.5 33.8 18.3 29.1 21.6 18.9 17.9 15.4 21.1 21.3 19.0 18.7 22.5 18.5 45.8 3.2 7.5 31.0 23.2 16.6 13.0 23.4 14.2 12.6 19.9 14.6 3.4 18.6 14.8 11.0 37.5 28.5 32.9 21.0 9.8 26.5 2.7 9.7 11.7 35.8 27.5 11.1 17.3 35.4 37.2 16.2 29.6 11.0 19.0 22.2 45.0 11.9 49.8 18.5 14.8 11.6 14.2 49.0 18.5 5.3 17.1 27.7 5.4 9.4 18.5 15.8 29.9 12.1 30.2 35.9 22.9 13.2 24.3 20.2 41.5 10.3 8.3 13.2 13.1 21.8 14.4 9.3 16.2 15.9 16.9 40.0 35.2 18.6 15.1 20.1 STIP1 "HOP, STI1" ENSG00000168439 "Stress induced phosphoprotein 1" P31948 11 64185272-64204543 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 340.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017448, HPA039291, HPA044062" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 27: Non-specific - Gene expression" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" Cytosol "CAB017448: AB_10618972, HPA039291: AB_2676428, HPA044062: AB_2678795" "unprognostic (2.49e-3)" "unprognostic (6.04e-2)" "unprognostic (1.57e-1)" "unprognostic (4.65e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.23e-4)" "prognostic unfavorable (6.18e-8)" "unprognostic (2.16e-3)" "unprognostic (4.56e-2)" "unprognostic (1.12e-2)" "unprognostic (3.56e-2)" "unprognostic (3.04e-3)" "unprognostic (1.70e-1)" "unprognostic (6.72e-2)" "unprognostic (8.23e-2)" "unprognostic (7.16e-2)" "unprognostic (2.99e-2)" 68.0 128.0 114.5 70.2 119.9 61.3 49.7 124.6 340.6 69.5 122.1 72.9 40.4 74.1 49.0 79.5 72.4 43.5 98.5 120.2 133.4 86.7 68.9 70.8 72.9 124.0 131.3 87.6 53.3 61.4 71.7 77.5 139.2 60.7 56.0 62.9 56.1 56.1 140.3 60.5 53.9 66.7 123.6 69.0 66.1 126.3 134.2 66.2 57.6 92.2 88.2 81.2 63.8 159.4 321.0 486.3 298.1 251.7 161.8 108.1 271.5 277.2 150.1 393.9 228.1 361.3 265.2 371.1 322.9 220.3 475.4 329.7 745.4 280.3 427.6 302.1 311.7 521.5 302.6 336.7 142.8 278.7 325.1 109.4 174.5 327.1 242.7 162.4 284.2 276.1 537.2 209.5 232.1 468.8 432.0 388.6 366.4 306.0 407.2 418.3 279.1 385.6 282.8 271.8 242.7 217.3 314.4 338.9 266.7 310.3 357.1 194.0 253.8 252.0 310.9 333.1 389.0 189.8 434.0 388.0 328.8 282.6 374.1 61.0 66.8 57.4 87.6 95.1 88.2 85.9 65.5 79.5 69.9 68.5 72.7 81.6 20.0 108.2 114.6 58.1 66.1 119.1 114.5 119.9 124.6 340.6 120.2 133.4 124.0 131.3 139.2 123.6 134.2 159.4 31.3 44.8 32.9 7.8 40.0 80.4 184.1 61.5 40.9 37.5 32.5 29.8 46.1 31.5 59.1 20.2 41.7 124.8 39.8 38.3 49.0 76.3 31.0 65.8 48.6 45.9 67.3 69.0 9.5 55.2 146.1 49.6 24.5 51.1 79.3 47.8 14.3 27.4 91.5 63.9 14.9 39.9 97.6 21.9 90.3 77.5 27.4 46.7 62.2 12.2 51.8 36.9 53.5 11.1 17.2 69.5 32.7 39.9 56.4 75.7 22.3 39.6 85.8 36.7 26.3 36.1 65.4 96.3 118.6 47.6 72.0 211.0 67.0 62.8 48.6 95.3 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 15.2 24.9 17.6 11.8 17.5 15.0 16.2 16.3 20.5 14.0 19.5 20.0 17.3 13.8 20.8 22.8 18.1 13.0 19.0 16.5 16.8 26.5 43.2 14.3 17.6 17.9 17.5 14.8 30.9 22.7 19.8 9.2 16.9 20.3 13.5 7.9 20.0 10.9 14.4 17.3 17.8 9.9 17.4 21.2 24.2 27.7 18.6 20.5 19.3 8.2 14.5 17.8 14.8 16.5 14.1 18.8 15.7 13.2 40.0 40.0 17.9 17.8 23.6 14.3 14.7 21.2 31.0 8.3 24.4 32.0 23.4 14.5 18.5 30.0 7.8 20.0 19.8 17.7 15.4 19.1 34.9 17.6 20.1 40.1 48.1 20.8 57.4 29.8 17.9 18.7 23.1 21.5 26.8 27.1 19.4 38.0 14.5 25.7 10.3 18.1 17.5 24.9 32.2 16.1 12.3 14.6 5.8 25.5 39.0 11.2 27.4 36.4 13.7 20.6 14.0 16.4 17.4 25.9 12.1 19.5 22.9 18.4 18.3 1.6 7.0 5.3 4.9 3.8 5.5 7.2 6.0 9.2 6.8 6.0 6.1 7.9 4.1 14.5 3.1 5.8 7.3 8.7 17.6 17.5 16.3 20.5 16.5 16.8 17.9 17.5 16.9 17.4 18.6 16.5 11.8 6.4 5.6 3.6 22.4 9.8 18.1 32.6 24.5 7.9 31.8 31.8 9.5 24.3 19.7 7.3 16.7 24.0 23.6 27.6 68.4 40.3 87.2 21.4 13.3 14.0 25.8 36.0 2.2 58.5 25.0 15.8 17.3 12.9 8.2 17.9 12.5 43.7 28.4 13.5 2.7 38.7 16.2 27.1 17.6 70.3 15.2 17.8 21.4 0.0 38.4 22.1 44.3 4.0 6.8 33.3 44.3 13.5 27.6 18.6 58.9 80.2 19.6 19.1 0.0 11.9 19.2 43.1 9.6 28.2 11.2 12.9 22.1 33.6 34.2 20.8 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 70.0;epididymis: 56.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.2;dendritic cells: 42.7;NK-cells: 53.5;Syncytiotrophoblasts: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 140.1;U-937: 144.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 360000 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 6.0 2.5 1.0 15.2 2.7 70.0 6.0 1.7 1.3 6.8 2.5 11.5 9.6 46.6 56.3 13.1 7.4 5.6 1.4 0.7 1.5 3.5 5.2 7.2 26.2 0.8 0.8 2.1 3.7 23.5 5.0 25.2 0.7 20.0 11.6 0.2 7.3 35.8 0.9 7.8 6.9 38.1 0.6 13.2 12.2 2.2 3.8 41.3 3.7 1.2 23.5 11.8 7.4 0.7 32.9 11.3 1.3 0.0 5.2 4.9 72.0 1.0 4.0 0.5 0.6 30.1 29.0 44.6 19.4 7.3 22.1 36.5 80.8 51.1 0.0 39.1 66.6 64.6 25.9 28.4 4.7 135.3 5.1 6.9 30.0 0.1 33.7 15.1 14.2 60.0 29.2 40.4 12.2 29.0 140.1 124.9 64.4 22.0 4.3 99.9 39.7 57.9 32.6 51.8 26.6 29.6 19.2 17.0 0.9 54.9 22.0 35.4 0.3 12.8 13.7 39.0 47.9 31.0 52.0 49.8 11.7 144.8 6.5 59.1 9.5 31.6 22.8 12.4 22.4 14.5 15.2 19.6 11.3 12.6 19.7 20.6 18.2 41.0 22.7 4.2 7.2 20.4 1.0 2.7 1.7 1.3 0.7 1.5 0.8 0.8 0.7 0.6 3.8 0.7 0.9 22.4 15.6 0.0 24.7 0.0 36.4 0.0 6.8 0.0 5.9 10.9 1.3 5.7 8.1 11.0 0.0 55.2 42.7 6.5 3.9 4.5 0.6 7.4 1.8 1.7 1.2 12.8 2.0 7.1 34.7 9.6 15.3 17.9 11.4 0.5 1.4 4.4 11.8 0.0 1.4 4.8 0.0 8.8 0.0 0.4 3.4 17.3 0.0 2.8 13.5 0.0 53.5 0.0 0.2 10.9 4.0 2.2 14.5 33.6 1.9 1.5 6.6 0.0 6.6 6.7 3.6 1.8 2.5 16.1 0.0 59.1 27.4 0.6 6.5 18.2 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051480-5500994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;lymphoid tissue: 19.5" "Cell type enhanced" "Detected in many" "Early spermatids: 108.2;Late spermatids: 39.3;Microglial cells: 27.2;Oligodendrocyte precursor cells: 169.4" "Cancer enhanced" "Detected in many" "renal cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 27.5;HUVEC TERT2: 27.5;REH: 25.2;U-2197: 43.8;WM-115: 112.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: AB_1858913" "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 3.5 0.3 2.3 1.2 7.8 1.5 4.3 1.9 2.3 3.3 1.5 1.1 0.5 3.5 0.3 1.2 1.3 1.4 0.4 2.1 4.5 15.0 0.1 0.9 1.8 3.7 3.9 0.6 1.8 0.3 0.4 3.2 3.7 0.6 1.1 0.8 1.0 0.9 1.3 2.4 1.1 2.5 3.6 0.2 6.0 4.5 3.5 19.5 1.7 1.7 1.0 3.1 1.5 3.6 0.0 14.0 0.8 0.0 0.6 1.0 0.0 9.7 1.1 6.3 0.2 0.1 0.0 0.0 2.1 19.7 27.5 0.1 1.5 0.0 2.3 0.0 0.0 0.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.2 27.5 1.4 0.0 0.1 3.4 0.0 0.0 2.0 4.1 0.0 0.0 25.2 0.1 0.0 6.2 0.0 0.4 0.0 0.0 0.1 8.5 0.6 0.0 0.0 7.1 0.2 2.8 43.8 0.0 0.9 0.1 0.0 0.1 0.0 112.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 7.8 1.9 2.3 2.1 4.5 3.7 3.9 3.7 3.6 3.5 3.6 3.6 0.0 1.1 1.6 0.0 2.3 0.2 0.0 0.0 0.0 4.2 1.7 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 17.6 1.1 108.2 0.2 0.1 3.2 0.0 0.0 3.7 0.0 0.1 5.5 4.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 14.4 0.0 0.0 0.0 1.2 39.3 1.5 1.1 5.4 27.2 0.5 0.0 0.0 169.4 1.3 0.4 0.0 1.2 0.0 0.1 0.0 18.9 0.0 0.0 0.0 0.6 0.4 1.2 5.5 0.0 1.0 0.0 0.2 0.4 0.0 0.1 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 49.3;testis: 51.8" "Cell type enhanced" "Detected in many" "Astrocytes: 213.8;Early spermatids: 98.8;Endometrial ciliated cells: 220.9;Late spermatids: 157.0;Oligodendrocyte precursor cells: 117.6;Respiratory ciliated cells: 155.3;Spermatocytes: 148.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 4.1;naive B-cell: 2.2" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in many" "Daudi: 23.0;hTERT-RPE1: 22.0;Karpas-707: 21.2;SCLC-21H: 22.9;U-251 MG: 24.3;U-266/84: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: AB_2683257" "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favorable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 1.3 8.1 6.7 2.0 6.6 1.3 0.5 8.5 4.9 5.6 49.3 8.3 3.3 12.0 11.3 2.7 42.3 5.1 16.2 6.1 10.1 10.2 0.4 7.1 2.0 14.7 15.6 13.4 6.5 23.1 24.1 0.1 13.3 6.4 1.5 15.6 2.1 11.5 3.9 0.2 3.4 9.3 12.0 1.5 6.0 51.8 12.8 3.8 20.0 6.0 2.2 3.4 1.7 8.3 0.0 3.4 15.4 0.0 0.0 0.0 0.0 3.0 3.1 7.0 6.2 2.2 0.0 23.0 11.5 0.6 8.7 0.0 6.9 2.5 6.0 0.0 18.9 0.0 4.2 5.6 2.5 13.4 0.0 1.1 0.0 0.2 0.0 22.0 0.5 11.2 0.0 21.2 0.3 0.0 0.4 0.0 11.2 0.0 0.0 8.8 2.2 14.3 6.1 0.0 22.9 6.2 0.0 0.0 0.1 4.3 0.0 1.3 0.0 0.0 10.6 0.2 24.3 5.1 21.2 0.3 6.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.7 0.0 2.2 0.0 0.6 0.0 0.1 0.0 0.4 0.1 0.2 6.7 6.6 8.5 4.9 6.1 10.1 14.7 15.6 13.3 12.0 12.8 8.3 0.1 19.2 14.5 213.8 6.2 0.0 1.3 1.9 0.0 20.7 0.1 0.3 37.8 8.6 27.5 20.2 70.9 0.1 1.4 0.2 3.9 9.5 98.8 220.9 5.5 1.8 9.1 1.7 12.0 4.9 3.3 5.0 6.1 17.8 1.3 29.3 0.4 0.0 0.3 1.7 15.4 1.6 6.1 0.0 0.0 157.0 4.4 0.6 0.0 23.4 0.0 31.0 0.0 117.6 19.7 4.4 0.4 17.0 5.2 0.5 3.6 13.5 155.3 77.4 0.0 0.2 2.7 148.3 26.8 0.2 0.0 0.0 1.3 6.3 3.5 0.0 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966479-45080021 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.7" "Cell type enhanced" "Detected in all" "B-cells: 372.8;dendritic cells: 341.8;Langerhans cells: 606.9;monocytes: 367.5;Plasma cells: 336.2;T-cells: 414.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 45000 "Cluster 18: Basophils - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: AB_2144632, HPA015270: AB_1854150" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (8.83e-2)" "unprognostic (8.49e-3)" "unprognostic (2.95e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (1.18e-2)" 10.0 8.5 6.9 33.8 8.0 57.7 9.1 6.2 10.8 7.9 9.9 11.1 10.2 8.5 7.6 9.1 6.2 11.7 4.6 7.2 8.7 6.0 9.2 15.9 43.1 8.7 7.6 7.0 6.0 5.9 4.1 10.4 9.2 6.7 13.0 7.3 7.4 8.0 3.3 11.2 13.5 9.3 8.3 30.4 12.7 9.7 7.5 33.1 7.6 4.9 41.7 15.0 6.9 10.3 27.8 18.7 23.3 16.1 13.5 16.9 16.0 23.6 35.7 39.4 35.6 52.7 14.6 66.6 20.4 16.9 33.4 28.5 24.3 31.8 49.7 30.8 13.8 48.6 27.8 36.8 23.8 63.5 66.4 13.8 25.6 36.7 39.6 19.4 14.6 44.6 23.5 37.0 19.9 21.7 47.6 42.3 13.9 17.7 12.5 30.2 25.2 31.2 14.4 18.7 10.9 13.2 35.6 20.0 27.0 17.2 18.3 39.1 18.7 29.2 28.6 34.4 27.8 48.4 41.7 73.2 28.6 29.5 22.0 80.6 19.7 54.8 34.4 19.9 34.3 26.2 32.2 32.0 18.4 26.9 33.1 28.0 101.8 28.5 38.0 10.0 34.3 22.3 6.9 8.0 6.2 10.8 7.2 8.7 8.7 7.6 9.2 8.3 7.5 10.3 26.2 16.0 24.6 18.9 372.8 55.7 49.3 33.8 28.5 27.3 22.9 17.4 7.6 14.3 25.2 42.3 52.1 24.1 341.8 23.7 9.8 16.3 5.9 19.1 25.1 32.1 25.7 46.3 76.7 17.6 30.3 29.7 34.1 25.1 133.6 114.0 26.0 22.0 61.1 43.7 38.2 20.7 28.5 109.3 606.9 5.0 22.7 154.4 133.4 85.3 367.5 20.2 278.1 34.2 48.1 21.6 27.9 17.0 336.2 32.6 23.2 13.4 26.1 69.9 13.1 25.5 29.2 44.2 42.4 20.9 53.0 19.4 414.5 48.1 19.5 45.5 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.2;choroid plexus: 30.8" "Group enriched" "Detected in many" 5 "Astrocytes: 85.2;Endometrial ciliated cells: 67.4;Respiratory ciliated cells: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 8.6;HAP1: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Intracellular and membrane" No NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: AB_2675700, HPA037845: AB_10671369" "prognostic favorable (3.37e-5)" "unprognostic (5.53e-3)" "unprognostic (6.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.63e-3)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.52e-1)" "unprognostic (2.45e-3)" "unprognostic (5.33e-3)" "unprognostic (5.29e-2)" "unprognostic (3.87e-2)" "unprognostic (8.77e-2)" "unprognostic (3.06e-2)" "unprognostic (2.33e-1)" "unprognostic (3.46e-2)" 6.3 5.1 26.4 0.5 23.6 0.2 4.2 14.9 33.2 1.9 30.8 1.6 1.1 1.6 7.4 1.4 12.5 0.9 0.4 23.9 22.4 2.8 0.3 1.3 1.2 16.5 24.9 1.1 1.4 6.5 7.2 0.8 17.4 1.2 1.6 0.7 1.6 1.1 1.3 0.9 2.1 0.8 16.3 0.4 3.4 2.5 26.2 6.7 3.1 0.8 1.0 2.5 0.7 20.5 1.8 2.0 4.2 8.6 1.8 0.0 2.5 0.2 0.1 1.2 1.3 1.8 2.6 1.7 2.4 0.0 3.3 0.5 8.1 0.0 0.6 2.0 3.4 0.1 0.4 2.6 0.2 2.3 3.1 0.2 0.1 0.2 0.0 0.2 0.1 4.5 0.4 0.2 0.1 1.8 3.9 2.8 1.4 0.4 1.2 2.8 0.1 0.0 2.6 4.6 1.3 3.9 3.1 0.8 0.6 2.7 1.9 1.8 0.0 0.0 0.2 0.0 1.3 0.7 1.6 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.0 1.0 0.0 0.0 26.4 23.6 14.9 33.2 23.9 22.4 16.5 24.9 17.4 16.3 26.2 20.5 0.3 0.0 0.5 85.2 0.3 1.5 4.5 0.9 1.2 0.7 5.1 4.1 0.5 0.0 5.6 1.8 0.0 1.6 3.1 0.4 3.9 0.1 0.3 67.4 1.7 0.4 0.0 1.7 11.4 0.4 0.5 0.6 0.5 4.2 2.5 0.8 0.0 0.2 0.1 0.0 9.9 2.5 2.0 0.3 0.7 0.7 1.2 0.2 0.0 1.9 0.1 1.9 2.1 6.0 2.1 0.1 0.3 0.0 0.6 1.7 0.8 1.8 42.8 0.4 6.6 1.5 5.0 1.4 8.8 0.4 0.4 1.2 0.7 6.9 5.3 1.8 STOX2 DKFZp762K222 ENSG00000173320 "Storkhead box 2" Q9P2F5 4 183797692-184023526 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 181.7;Inhibitory neurons: 192.3;Microglial cells: 72.1;Oligodendrocyte precursor cells: 91.0;Oligodendrocytes: 153.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;HeLa: 12.7;NTERA-2: 16.8;SH-SY5Y: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049776, HPA065002" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Actin filaments" "HPA049776: AB_2680875, HPA065002: " "unprognostic (9.79e-3)" "unprognostic (3.46e-1)" "unprognostic (2.10e-1)" "unprognostic (6.57e-3)" "unprognostic (3.33e-1)" "unprognostic (6.41e-2)" "unprognostic (4.57e-4)" "unprognostic (8.97e-3)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" "unprognostic (7.06e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-3)" "unprognostic (2.49e-1)" 1.8 1.6 8.3 0.7 8.2 6.0 1.8 4.2 13.3 2.1 2.3 1.7 0.9 1.9 3.4 5.0 2.7 1.3 3.6 11.1 3.1 2.7 2.0 2.1 0.6 2.7 3.9 3.3 4.9 4.0 7.0 1.4 3.9 2.3 0.9 3.8 7.3 2.3 2.1 3.9 1.3 1.8 2.0 4.1 2.3 0.9 6.6 4.1 5.8 2.1 1.1 2.5 3.3 11.5 2.1 4.3 13.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.3 1.7 0.0 2.6 0.0 2.7 0.2 7.4 1.2 0.0 0.0 5.9 0.0 12.7 0.1 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 1.8 0.0 0.6 0.0 0.1 16.8 0.0 0.6 0.1 4.8 0.0 3.1 4.1 6.8 15.8 3.2 0.0 0.0 4.7 0.2 0.4 0.0 0.0 2.8 0.0 0.1 0.1 3.8 2.1 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 8.2 4.2 13.3 11.1 3.1 2.7 3.9 3.9 2.0 6.6 11.5 12.7 12.8 22.1 39.2 0.4 4.2 6.0 3.7 8.6 28.2 3.8 4.6 20.7 5.7 8.7 7.3 0.0 2.7 0.0 0.2 3.9 5.4 1.2 7.2 0.7 18.5 1.8 0.0 181.7 3.1 2.1 5.8 3.1 3.7 0.0 0.3 21.4 5.6 1.1 33.7 192.3 0.4 2.0 2.2 1.5 2.6 0.6 0.8 1.8 72.1 0.0 12.4 0.0 91.0 153.5 2.1 0.0 4.5 1.3 5.2 0.0 4.0 16.8 3.4 0.0 4.8 4.5 0.6 2.0 17.8 3.3 0.7 0.7 3.6 0.4 3.4 STRN3 "PPP2R6B, S/G2NA, SG2NA" ENSG00000196792 "Striatin 3" Q13033 14 30893799-31026401 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003392, HPA004636, CAB069925" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoplasm, Actin filaments" "CAB069925: AB_1146988, HPA003392: AB_1079942, HPA004636: AB_1079940" "unprognostic (4.08e-1)" "unprognostic (8.66e-2)" "unprognostic (8.08e-2)" "unprognostic (4.22e-2)" "unprognostic (3.06e-2)" "unprognostic (7.74e-3)" "unprognostic (3.37e-2)" "unprognostic (2.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.53e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "prognostic favorable (9.66e-4)" "unprognostic (8.74e-2)" "unprognostic (7.85e-2)" "unprognostic (4.83e-2)" "unprognostic (1.01e-2)" 18.9 13.4 8.4 9.3 8.3 10.0 11.6 14.9 11.2 14.0 8.9 16.1 7.3 12.4 13.8 15.3 9.9 12.4 18.5 7.5 16.4 13.9 21.5 10.0 7.5 7.7 9.8 10.1 12.6 13.9 9.3 11.9 7.5 13.7 12.6 14.2 10.3 14.1 39.2 11.7 9.7 18.0 6.0 10.4 11.2 20.9 10.7 9.4 13.7 28.5 9.0 14.7 11.6 10.6 33.7 29.2 31.0 22.0 27.4 20.4 25.8 33.0 23.2 24.9 26.3 37.7 22.4 18.4 22.0 23.2 12.6 18.2 33.5 18.1 37.7 17.5 12.3 19.2 19.6 73.6 28.8 15.6 19.8 19.9 20.8 19.5 24.8 23.9 21.5 16.7 22.8 17.8 25.4 21.5 21.3 16.3 15.3 24.1 25.5 15.0 35.5 4.9 39.2 47.7 19.1 15.5 32.8 23.6 17.7 28.4 27.7 14.5 28.0 24.8 21.3 14.7 12.4 15.7 21.4 17.8 12.7 11.2 20.5 4.1 3.5 4.7 3.3 4.3 4.4 3.4 4.2 3.7 3.1 3.2 4.1 4.8 4.3 4.2 3.5 5.7 3.6 1.3 8.4 8.3 14.9 11.2 7.5 16.4 7.7 9.8 7.5 6.0 10.7 10.6 37.1 22.4 22.4 82.3 19.5 98.1 57.5 17.9 23.9 27.2 37.1 25.1 51.7 28.6 22.1 31.3 27.1 22.1 17.5 34.1 11.7 38.9 21.8 32.7 48.0 36.0 31.9 43.8 110.9 26.3 19.9 39.6 20.4 46.9 8.8 21.7 35.0 43.1 12.8 37.0 119.0 18.8 16.2 23.9 45.7 13.4 26.8 22.9 44.4 92.8 18.9 24.6 11.3 102.1 139.2 40.3 13.2 27.8 31.3 49.6 13.2 43.3 25.2 30.2 26.3 52.3 51.9 59.8 53.6 31.4 96.5 33.2 21.4 26.1 16.3 53.6 STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: AB_10794261, HPA055300: AB_2682778" "unprognostic (3.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.14e-2)" "unprognostic (2.78e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (8.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" 64.2 30.1 38.1 26.6 39.0 10.8 37.0 40.8 45.6 28.8 25.4 30.7 36.3 30.9 62.9 39.2 23.9 39.8 20.9 37.3 41.7 35.2 29.1 50.0 25.6 42.0 45.3 22.1 30.3 46.5 26.6 33.3 43.6 30.7 32.5 43.2 26.9 32.1 21.4 27.0 32.8 35.9 42.2 30.5 65.5 13.4 38.4 17.3 94.7 27.1 22.2 39.1 23.4 44.6 23.2 10.9 28.8 19.0 53.9 65.0 14.8 47.9 70.3 43.1 48.5 13.5 29.5 25.2 49.6 64.6 18.5 19.0 19.2 23.9 42.9 22.2 22.8 14.4 12.0 13.7 42.2 16.1 29.0 61.3 28.7 60.6 34.5 35.3 70.3 14.3 19.1 24.6 47.7 8.5 13.7 12.3 12.1 34.3 15.3 8.7 23.1 15.5 38.1 37.5 32.3 17.6 22.4 19.3 35.2 23.3 13.1 14.0 76.2 21.9 12.5 50.0 16.6 14.5 11.2 14.3 35.1 24.1 31.2 24.6 35.7 13.7 6.1 39.4 10.6 13.6 7.3 9.7 25.2 10.8 8.1 6.8 16.5 9.2 40.6 12.4 7.9 17.4 38.1 39.0 40.8 45.6 37.3 41.7 42.0 45.3 43.6 42.2 38.4 44.6 93.0 54.5 36.3 25.1 43.6 109.4 97.2 30.7 51.2 46.2 42.0 25.7 18.9 30.0 40.8 57.0 31.3 30.0 28.3 82.8 37.2 51.9 2.0 34.7 33.1 71.1 41.3 17.7 70.9 58.4 33.5 53.2 108.6 49.4 22.8 26.7 47.8 20.4 50.6 26.9 65.7 29.5 14.2 91.4 77.7 4.2 36.1 62.3 53.4 56.2 41.3 67.9 36.0 34.7 59.1 68.4 58.6 47.4 33.9 74.9 51.3 69.7 27.4 51.2 39.5 45.7 57.5 20.0 20.1 69.9 99.2 78.0 31.6 54.0 29.9 99.9 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SUGT1 SGT1 ENSG00000165416 "SGT1 homolog, MIS12 kinetochore complex assembly cochaperone" Q9Y2Z0 13 52652709-52700909 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015942, HPA043949" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 17000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB015942: , HPA043949: AB_2678745" "unprognostic (3.66e-2)" "unprognostic (3.98e-2)" "unprognostic (3.57e-1)" "unprognostic (1.22e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (8.69e-4)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (3.76e-1)" "unprognostic (1.96e-3)" "unprognostic (9.51e-2)" "unprognostic (1.12e-1)" "unprognostic (6.83e-2)" "unprognostic (2.82e-3)" "unprognostic (9.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-1)" 27.4 31.4 33.4 25.5 38.1 32.0 23.6 38.6 55.6 23.0 33.1 25.5 27.3 19.6 20.3 30.1 19.4 19.6 37.0 34.8 37.0 31.7 36.5 22.5 27.4 34.8 34.8 21.5 30.6 19.8 26.9 25.9 36.9 19.6 26.9 22.2 25.2 16.3 29.6 24.5 26.8 22.1 35.3 23.2 26.8 34.5 36.4 29.8 21.1 28.1 29.9 27.3 24.3 48.1 47.0 50.2 72.9 55.6 70.4 57.0 69.8 100.8 66.3 61.7 49.0 110.3 114.7 102.4 27.9 62.8 89.5 79.0 90.6 57.9 90.0 85.3 37.7 95.1 65.8 84.4 51.1 74.8 68.7 40.0 51.7 63.9 48.2 79.0 105.0 64.8 90.5 32.7 95.7 33.4 70.3 136.6 85.3 183.9 47.8 79.6 42.4 44.4 108.0 51.7 24.1 30.7 52.1 42.2 49.8 82.6 43.5 70.3 76.1 51.3 59.9 59.6 87.6 25.7 38.9 91.5 30.8 59.2 75.5 63.6 29.0 49.0 24.3 34.5 23.9 30.9 31.4 33.2 32.9 30.3 23.8 26.6 4.1 33.2 34.1 41.0 46.0 25.2 33.4 38.1 38.6 55.6 34.8 37.0 34.8 34.8 36.9 35.3 36.4 48.1 82.1 38.5 36.0 22.2 46.1 39.8 65.4 68.2 38.1 52.6 40.6 55.8 126.2 32.9 51.8 51.5 25.0 67.0 78.3 52.3 78.2 88.3 185.6 112.0 79.0 65.9 34.1 65.2 19.9 89.0 143.0 60.9 50.0 75.1 36.8 49.7 43.5 38.3 97.8 50.5 23.0 58.2 54.9 44.5 43.9 95.7 58.7 54.3 48.0 13.1 123.7 91.8 58.7 21.1 47.6 85.2 55.0 59.8 58.3 44.1 74.3 100.9 67.8 56.6 26.3 72.4 92.1 146.7 101.0 45.7 43.2 74.4 61.1 56.1 55.5 52.3 SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Nuclear bodies" "CAB004269: AB_628300, HPA056956: AB_2683285" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.49e-1)" "unprognostic (2.52e-3)" "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.78e-3)" "prognostic favorable (7.93e-4)" "unprognostic (7.06e-3)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" "unprognostic (2.82e-2)" "unprognostic (2.19e-1)" 77.5 99.1 79.4 62.7 84.9 133.7 83.6 89.0 99.9 68.9 84.4 82.7 72.0 65.1 86.3 71.6 65.7 71.7 79.8 85.6 85.3 118.1 174.1 66.5 86.4 79.9 80.1 54.5 55.8 91.6 56.7 75.6 81.1 75.3 82.8 80.2 66.8 61.9 107.5 57.1 80.5 71.5 78.9 68.1 73.8 54.7 81.4 112.1 102.3 103.3 95.4 77.9 54.9 86.6 164.1 82.4 291.4 155.8 159.3 168.5 129.7 171.0 214.6 209.0 274.6 178.1 203.7 111.6 153.5 199.0 193.5 117.1 242.2 237.9 325.0 104.8 185.7 207.6 159.0 211.2 114.9 237.2 188.5 130.9 225.2 164.0 123.9 195.1 197.3 219.0 194.2 176.0 226.4 141.1 298.3 391.6 351.7 168.5 172.2 190.9 163.2 197.9 255.5 134.3 201.7 219.3 140.3 133.6 236.4 313.9 120.0 223.2 139.9 152.5 153.0 141.4 152.8 151.7 322.9 285.8 170.2 165.4 137.2 242.2 220.0 284.2 169.2 226.5 179.6 276.3 206.8 200.0 223.6 231.6 193.8 202.3 256.5 246.5 239.7 187.8 329.0 394.7 79.4 84.9 89.0 99.9 85.6 85.3 79.9 80.1 81.1 78.9 81.4 86.6 182.7 112.2 61.1 10.7 143.1 422.1 204.4 448.6 177.6 99.6 196.8 170.2 58.1 130.1 215.3 189.4 64.6 259.4 162.3 136.6 481.3 250.4 91.3 148.3 115.1 170.7 142.4 140.1 31.4 173.3 297.8 161.8 89.7 115.2 92.6 114.7 142.8 202.1 205.3 87.5 27.8 156.4 319.4 140.7 330.2 28.0 129.8 137.7 211.7 15.9 241.3 182.3 176.1 16.6 21.2 208.1 191.1 127.9 130.5 258.5 272.2 534.4 185.5 87.8 111.7 92.5 221.9 212.0 141.5 183.9 424.5 209.7 174.5 134.9 157.5 254.1 SUPT6H "KIAA0162, SPT6H" ENSG00000109111 "SPT6 homolog, histone chaperone and transcription elongation factor" Q7KZ85 17 28662198-28702679 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012416, HPA036382" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB012416: , HPA036382: AB_2675094" "unprognostic (8.18e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-1)" "unprognostic (8.23e-2)" "prognostic unfavorable (3.68e-5)" "unprognostic (1.02e-1)" "unprognostic (2.18e-2)" "unprognostic (9.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.17e-1)" "prognostic favorable (4.36e-5)" "unprognostic (4.75e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.06e-2)" 31.2 33.5 24.6 25.4 25.8 65.3 28.3 25.0 26.8 27.0 26.8 36.6 20.0 30.6 26.8 26.5 26.6 24.7 28.8 24.0 29.0 25.6 35.8 28.9 28.4 24.0 25.2 31.2 31.4 30.8 34.3 27.8 24.3 28.7 20.9 29.2 29.1 25.6 54.5 39.2 32.2 27.3 21.6 34.4 31.3 21.4 28.7 34.0 28.9 32.6 30.3 32.1 25.6 25.6 49.4 101.3 49.8 57.1 59.1 39.3 38.2 66.2 70.3 76.3 67.8 94.7 21.5 52.1 33.6 66.5 58.7 57.5 73.6 48.1 78.4 97.6 65.4 72.9 83.2 59.4 49.4 77.2 77.9 54.6 28.4 81.2 53.6 50.3 50.8 50.3 72.9 59.7 55.1 59.1 76.9 33.4 38.7 43.2 32.4 38.7 91.2 42.7 37.6 95.9 37.8 49.9 77.6 120.5 41.6 67.9 74.2 54.2 80.6 59.8 49.4 57.5 85.3 75.4 62.2 74.4 67.5 34.4 50.5 14.7 4.5 4.4 3.7 2.9 3.9 4.5 3.1 4.1 3.7 4.5 3.1 2.8 6.8 4.3 5.0 6.2 3.1 3.1 24.6 25.8 25.0 26.8 24.0 29.0 24.0 25.2 24.3 21.6 28.7 25.6 33.9 38.5 51.0 24.2 36.5 22.4 19.2 16.8 43.3 29.5 27.4 26.0 51.6 22.8 28.4 20.2 56.3 24.4 38.4 29.5 5.9 22.1 5.4 31.0 45.3 32.6 31.0 33.0 21.6 21.3 21.3 32.7 46.4 49.1 50.5 36.6 22.9 33.9 23.7 30.3 19.7 23.1 8.2 23.0 22.4 17.8 25.7 41.8 8.8 16.9 29.9 22.0 30.9 17.6 19.4 31.9 18.7 26.7 55.7 20.0 23.4 10.5 25.7 44.4 32.9 32.4 32.0 19.8 19.1 40.1 24.3 49.8 38.3 42.0 22.9 25.7 SURF2 ENSG00000148291 "Surfeit 2" Q15527 9 133356550-133361158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 105.8" "Group enriched" "Detected in many" 4 "Early spermatids: 448.9;Late spermatids: 992.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044340, HPA052213, HPA059710" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA044340: AB_2678900, HPA052213: AB_2681763, HPA059710: " "unprognostic (1.53e-1)" "unprognostic (6.10e-3)" "unprognostic (1.24e-3)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (6.27e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (1.85e-1)" "unprognostic (5.46e-3)" "unprognostic (8.28e-2)" "unprognostic (1.07e-3)" "unprognostic (1.09e-2)" "unprognostic (3.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" 15.3 16.4 13.2 5.4 13.0 5.4 15.3 13.5 15.6 13.8 12.5 16.9 7.6 13.1 6.0 25.8 13.4 3.5 18.9 12.9 12.6 27.7 22.6 12.1 7.1 14.3 13.5 13.2 28.9 5.8 24.2 3.1 13.2 17.7 2.9 4.7 17.0 4.4 21.6 28.3 14.2 2.3 12.6 15.6 20.1 105.8 13.5 6.1 15.5 3.9 4.9 16.5 15.6 13.3 17.4 29.4 12.1 15.1 8.7 6.7 25.4 8.6 7.5 13.5 7.0 40.5 14.0 17.1 12.2 5.8 11.6 46.5 19.2 21.1 6.1 16.7 26.8 13.5 34.7 15.3 17.3 22.6 9.9 8.1 24.5 19.3 28.1 4.8 6.3 20.6 21.9 11.5 9.3 104.3 23.4 15.0 38.1 41.3 56.0 25.7 18.1 40.4 11.8 19.6 44.8 22.7 19.3 31.7 27.0 7.3 33.8 10.6 12.1 20.3 20.7 21.2 31.2 14.3 30.6 18.7 13.0 13.3 20.8 23.7 23.0 18.6 24.3 24.8 32.1 22.3 29.7 28.0 20.3 27.5 27.9 26.6 10.3 21.1 18.6 22.7 42.1 20.8 13.2 13.0 13.5 15.6 12.9 12.6 14.3 13.5 13.2 12.6 13.5 13.3 26.7 12.8 11.5 3.3 23.2 84.1 27.6 53.7 50.7 18.3 31.1 55.1 13.3 35.8 27.3 22.0 2.1 37.8 25.0 30.6 105.7 73.0 448.9 44.4 16.8 20.9 36.5 28.2 3.5 81.6 28.4 19.3 19.9 16.5 9.5 12.9 22.5 23.6 29.7 13.5 2.9 21.5 36.7 25.5 31.7 992.3 26.1 18.7 42.7 0.0 33.1 28.2 34.0 1.0 3.5 63.8 37.4 24.5 19.6 28.8 81.4 78.0 60.2 23.6 65.7 24.4 26.8 169.9 107.3 43.0 88.2 25.6 38.2 52.2 30.1 23.2 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SURF6 "FLJ30322, RRP14" ENSG00000148296 "Surfeit 6" O75683 9 133328776-133336188 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 91.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023608, HPA074622" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA023608: AB_1857671, HPA074622: AB_2686703" "unprognostic (5.27e-3)" "unprognostic (8.67e-3)" "unprognostic (5.41e-3)" "unprognostic (3.69e-2)" "unprognostic (2.61e-1)" "unprognostic (3.20e-1)" "unprognostic (1.26e-3)" "unprognostic (3.60e-2)" "unprognostic (1.18e-1)" "unprognostic (9.37e-2)" "unprognostic (6.18e-3)" "unprognostic (9.32e-3)" "prognostic favorable (7.31e-5)" "unprognostic (1.50e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (2.66e-1)" 10.4 11.7 8.1 4.1 7.8 4.9 10.3 8.7 7.5 12.4 5.9 13.6 6.2 11.9 2.6 12.5 11.2 2.5 10.5 7.2 7.5 11.7 12.3 8.5 5.5 7.7 7.8 13.1 11.2 3.9 8.1 3.3 7.8 11.5 3.4 3.3 9.7 4.0 17.9 13.2 12.1 2.7 7.5 11.4 9.9 7.9 7.9 4.6 10.6 3.9 3.7 12.2 11.1 8.1 5.6 8.7 6.5 9.8 4.0 3.7 10.8 8.8 5.1 7.7 4.8 13.8 9.2 16.2 6.7 4.9 5.6 16.7 8.4 9.3 2.8 10.8 9.6 11.2 10.5 8.3 7.2 19.1 9.3 5.3 8.0 8.0 7.4 6.8 4.0 15.6 25.1 8.4 6.8 14.7 15.5 15.7 19.1 22.7 15.6 16.1 9.1 16.7 6.7 5.3 13.7 11.6 8.6 13.7 7.8 3.9 12.2 10.6 8.4 17.3 9.3 8.9 12.0 6.2 9.6 21.0 6.5 12.9 10.4 3.3 3.0 1.4 4.3 2.9 4.5 4.6 3.9 3.9 3.3 5.1 5.2 4.4 0.8 3.2 2.7 6.0 3.6 2.5 8.1 7.8 8.7 7.5 7.2 7.5 7.7 7.8 7.8 7.5 7.9 8.1 25.7 44.8 27.3 4.6 20.9 23.7 15.7 11.0 24.5 26.5 33.4 32.3 30.0 28.6 24.5 22.0 6.2 32.2 20.3 36.8 21.5 29.2 1.3 21.1 42.2 23.6 33.6 14.1 4.3 19.6 25.2 21.2 18.8 25.1 25.3 25.4 16.4 35.2 21.2 21.9 4.8 40.3 6.1 14.7 10.2 4.1 27.7 13.7 7.2 5.6 18.6 15.2 29.9 5.0 4.1 29.0 33.3 27.8 14.4 24.8 50.6 26.1 13.2 19.6 0.0 15.8 20.3 19.2 23.6 26.3 27.6 19.0 18.1 91.1 57.7 13.3 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 12.3 11.8 6.3 18.8 6.3 45.4 15.0 11.1 8.5 11.6 6.8 14.9 16.0 15.2 12.0 14.0 11.0 12.0 10.3 5.4 5.8 16.4 18.1 12.6 33.0 5.4 5.9 11.4 11.5 19.8 6.6 18.7 5.6 13.3 16.4 26.5 10.5 12.2 8.1 13.0 15.3 14.7 5.2 18.4 15.2 27.4 6.1 38.5 18.3 11.0 30.0 15.6 9.0 7.1 46.5 40.4 37.2 42.9 21.1 26.8 38.2 44.2 38.8 53.0 63.7 30.9 25.5 100.7 33.2 27.7 45.4 40.1 56.0 25.5 85.7 35.8 54.0 69.9 32.9 22.3 24.8 111.5 68.7 18.7 28.1 53.1 40.4 32.1 33.1 47.3 68.8 135.6 46.2 16.2 133.3 64.4 21.3 32.4 24.4 78.5 95.3 81.9 31.1 44.6 47.5 37.1 71.3 22.7 43.3 25.8 66.0 91.5 24.7 41.9 38.0 50.8 69.3 73.5 98.4 122.5 30.7 67.4 38.7 0.6 0.7 1.6 1.4 1.1 1.1 2.4 1.6 1.6 0.6 1.8 1.5 2.1 1.6 1.8 0.7 1.9 1.8 0.4 6.3 6.3 11.1 8.5 5.4 5.8 5.4 5.9 5.6 5.2 6.1 7.1 44.5 41.7 45.8 43.1 50.1 58.5 50.2 21.8 31.9 77.6 54.2 36.8 32.3 27.1 32.6 35.0 108.4 61.5 65.2 24.0 17.6 28.3 16.2 52.8 55.8 45.1 29.4 93.6 71.6 21.9 53.1 35.1 31.1 54.2 15.8 41.4 38.2 42.3 32.9 62.2 69.5 31.8 10.2 42.1 58.2 13.9 26.8 47.3 24.9 45.0 73.1 45.7 38.1 75.4 71.3 27.8 15.4 25.6 66.2 62.8 21.5 26.6 29.6 80.9 13.1 47.2 38.4 121.7 128.9 48.6 71.7 69.5 52.5 52.8 35.6 66.7 SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.0;Erythroid cells: 135.4;Spermatocytes: 158.0;Spermatogonia: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: AB_2072066" "prognostic favorable (6.33e-4)" "unprognostic (2.68e-2)" "unprognostic (2.91e-1)" "unprognostic (4.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.15e-2)" "unprognostic (3.35e-3)" "unprognostic (1.59e-2)" "unprognostic (6.73e-3)" "unprognostic (2.16e-1)" "unprognostic (5.37e-3)" "unprognostic (1.17e-3)" "unprognostic (7.07e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" 34.7 15.1 36.4 13.7 37.7 43.1 29.9 39.1 49.9 30.9 33.6 29.3 11.6 24.9 26.2 17.7 27.2 15.2 24.7 37.1 38.4 25.6 19.1 17.4 23.0 38.2 37.3 36.3 12.1 22.1 30.6 20.6 37.5 20.3 15.7 22.6 15.9 15.4 28.0 17.7 19.9 19.2 38.2 22.1 19.0 52.9 37.1 48.3 19.0 23.5 23.5 23.9 24.8 40.3 25.9 12.9 75.2 26.9 30.9 48.3 37.2 21.5 18.1 28.8 29.7 22.8 20.2 29.1 23.5 28.6 22.6 18.3 14.3 23.7 35.2 53.6 23.7 54.5 12.1 43.9 25.6 41.3 35.2 31.2 37.4 16.2 15.4 29.7 29.1 56.0 46.2 14.3 35.3 12.0 41.5 50.8 40.8 23.7 14.5 30.9 55.8 19.2 29.9 25.3 45.5 40.4 26.8 14.9 31.7 76.9 11.3 120.1 22.7 25.4 28.1 19.6 35.6 14.9 19.1 20.7 16.1 27.5 24.4 60.5 40.2 76.5 26.8 40.8 23.5 56.4 46.5 32.3 39.2 59.8 42.8 37.2 70.3 37.3 43.8 33.0 115.7 24.7 36.4 37.7 39.1 49.9 37.1 38.4 38.2 37.3 37.5 38.2 37.1 40.3 46.2 9.6 6.3 0.0 25.0 0.0 33.0 0.0 23.9 6.2 33.1 53.1 0.0 28.6 9.3 20.2 2.1 53.8 20.0 19.5 54.8 51.7 149.0 32.2 34.6 32.3 18.2 135.4 0.0 24.5 66.0 36.6 14.3 18.2 11.4 22.8 42.8 45.6 70.4 6.7 0.0 19.6 0.0 51.8 0.0 61.6 42.9 48.4 0.0 0.0 70.2 33.1 29.9 0.0 0.0 43.1 21.7 53.8 16.9 21.9 20.5 43.2 7.3 15.5 59.2 28.1 28.4 158.0 153.8 21.4 0.0 61.6 21.4 24.1 23.6 31.1 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SYAP1 "FLJ14495, PRO3113" ENSG00000169895 "Synapse associated protein 1" Q96A49 X 16719612-16765340 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000175, HPA000882, HPA048047" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA000175: AB_1080142, HPA000882: AB_2666128, HPA048047: AB_2680240" "unprognostic (4.66e-2)" "unprognostic (2.99e-2)" "unprognostic (1.25e-2)" "unprognostic (5.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (9.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.82e-1)" "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (3.95e-3)" "unprognostic (1.14e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-3)" 15.3 25.1 5.8 11.2 6.5 25.5 12.4 7.1 7.8 13.1 11.8 14.6 17.4 9.2 8.7 11.3 11.1 13.2 9.5 6.8 7.4 16.0 29.4 9.1 10.3 7.1 6.7 10.9 11.8 15.5 7.6 8.7 7.0 12.8 13.0 7.8 10.7 8.0 12.6 10.3 15.6 9.9 6.6 7.1 13.2 6.4 7.7 7.9 11.5 7.6 10.7 10.8 8.3 8.8 29.2 24.1 17.0 32.0 22.6 25.6 7.8 22.7 16.2 18.6 18.4 22.8 23.5 22.6 32.4 22.3 37.9 16.9 21.0 29.7 24.7 14.8 41.9 9.0 25.4 21.9 16.2 15.5 13.4 17.6 13.7 32.2 27.1 21.5 26.0 6.9 19.8 12.2 25.4 34.2 8.4 16.6 19.9 16.1 26.3 9.1 21.5 22.8 27.8 18.9 17.3 21.3 42.2 29.7 23.1 22.0 39.5 13.8 20.6 23.7 12.5 48.7 18.6 13.4 12.2 26.1 23.3 7.7 19.8 7.4 7.2 9.3 9.9 7.9 8.1 9.0 8.4 9.2 7.8 7.0 8.3 8.7 12.0 10.1 11.4 6.5 10.5 6.5 5.8 6.5 7.1 7.8 6.8 7.4 7.1 6.7 7.0 6.6 7.7 8.8 60.4 64.1 75.6 14.4 96.0 64.1 107.0 69.5 37.0 20.2 116.0 78.2 74.3 88.6 92.2 79.1 22.9 66.5 273.8 164.3 111.6 119.6 214.8 219.3 84.7 53.3 106.1 45.9 13.9 132.1 83.3 65.5 72.4 176.3 210.0 38.3 71.4 216.0 49.5 23.5 16.0 107.4 63.1 70.8 241.0 296.2 42.3 171.5 67.6 8.4 55.7 49.4 64.9 11.6 26.9 183.6 159.2 54.5 185.5 80.3 148.3 164.3 169.7 21.5 59.2 56.9 68.1 15.3 21.5 42.0 52.6 150.5 156.6 48.5 118.6 104.4 SYCE1 "bA108K14.6, C10orf94, CT76" ENSG00000171772 "Synaptonemal complex central element protein 1" Q8N0S2 10 133553901-133569835 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 70.9" "Group enriched" "Detected in many" 6 "Early spermatids: 141.2;Late spermatids: 112.6;Spermatocytes: 362.8;Spermatogonia: 170.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 18.5;U-2 OS: 15.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040208 Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA040208: AB_10796450" "unprognostic (5.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.85e-1)" "unprognostic (9.05e-2)" "unprognostic (1.61e-1)" "unprognostic (3.20e-1)" "unprognostic (5.75e-1)" "unprognostic (5.38e-2)" "unprognostic (3.36e-1)" "unprognostic (2.22e-2)" "unprognostic (7.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (2.42e-1)" 1.9 1.6 8.5 0.6 8.5 0.0 1.4 9.1 11.6 1.3 2.0 0.9 0.1 0.9 0.3 0.7 1.2 1.2 0.7 9.0 6.3 1.2 4.0 0.4 0.2 6.6 5.4 2.0 3.8 0.0 1.2 9.4 6.4 1.7 0.4 2.3 0.2 0.4 0.9 0.5 0.5 0.6 3.7 0.9 0.6 70.9 6.7 0.2 1.4 1.7 0.5 0.4 0.4 8.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.5 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.1 15.5 0.2 0.4 0.2 0.3 0.4 0.0 0.1 0.0 0.0 0.5 0.1 0.9 0.6 0.8 0.2 0.6 0.2 0.3 0.3 0.3 0.8 0.0 0.0 0.8 0.6 0.7 0.4 8.5 8.5 9.1 11.6 9.0 6.3 6.6 5.4 6.4 3.7 6.7 8.1 0.7 0.0 1.5 0.7 0.3 1.0 1.2 0.0 0.0 2.7 1.0 2.4 0.3 1.5 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 141.2 1.2 3.2 1.3 0.0 0.0 29.8 1.1 0.2 5.6 0.5 0.6 0.0 0.0 0.0 7.8 0.7 10.1 19.1 0.0 0.0 0.3 0.9 112.6 5.3 0.9 0.0 0.0 0.0 0.3 0.0 7.1 0.8 0.4 0.3 3.8 0.1 0.6 0.0 0.5 1.5 2.1 26.3 0.5 0.9 362.8 170.9 0.0 1.0 0.3 0.5 7.0 0.0 0.6 SYCE3 C22orf41 ENSG00000217442 "Synaptonemal complex central element protein 3" A1L190 22 50551112-50562919 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "testis: 142.1" "Cell type enhanced" "Detected in many" "Early spermatids: 497.2;Late spermatids: 99.0;Spermatocytes: 508.0;Spermatogonia: 182.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;Karpas-707: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA047813 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA047813: AB_2797234" "unprognostic (2.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.63e-1)" "unprognostic (1.73e-2)" "unprognostic (2.22e-1)" "unprognostic (2.98e-3)" "unprognostic (1.68e-2)" "unprognostic (4.05e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (2.57e-1)" "unprognostic (1.60e-1)" "unprognostic (1.55e-2)" "unprognostic (5.20e-2)" 0.4 1.1 1.7 0.5 1.7 0.3 1.1 1.7 3.0 0.4 1.5 0.7 0.2 0.0 1.6 0.5 1.2 1.0 0.3 1.7 1.8 2.8 1.8 0.6 0.5 1.9 2.0 0.0 0.4 0.6 1.3 0.3 2.1 0.4 0.1 1.3 0.5 0.1 0.1 0.5 0.2 0.0 1.6 0.2 0.4 142.1 1.8 0.8 1.7 0.0 0.3 0.5 0.2 1.8 0.2 0.4 0.1 0.1 0.3 0.3 0.2 0.3 0.0 0.1 0.0 0.0 5.0 0.2 1.7 0.0 1.0 0.0 0.5 0.5 0.0 0.0 0.2 0.0 0.4 0.0 2.1 0.0 0.9 1.3 1.1 0.2 0.8 0.2 0.0 1.0 0.0 4.1 0.2 1.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 2.3 0.6 1.5 0.4 1.3 0.0 1.2 0.9 0.2 1.2 1.0 0.0 0.4 0.4 0.0 0.0 1.0 0.2 0.7 0.5 0.1 0.1 0.0 0.7 0.8 0.0 0.6 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.1 4.3 0.0 0.5 0.0 0.0 0.1 1.7 1.7 1.7 3.0 1.7 1.8 1.9 2.0 2.1 1.6 1.8 1.8 0.3 0.0 0.0 0.0 0.1 0.1 0.4 3.7 2.8 0.8 5.6 5.6 0.5 2.8 2.1 1.8 0.0 5.9 0.1 0.4 3.9 1.7 497.2 2.7 0.4 0.7 0.0 0.0 0.1 0.6 3.2 0.2 0.0 2.0 0.0 0.0 0.7 3.2 1.7 0.0 0.1 0.1 4.1 1.2 0.0 99.0 10.8 0.8 0.0 0.0 2.9 1.2 0.0 0.0 0.2 0.9 0.1 7.2 0.0 0.6 0.4 7.6 4.7 0.8 46.0 0.0 0.7 508.0 182.4 0.8 0.1 3.7 0.1 0.0 0.2 0.8 SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.2" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 468.5" "Group enriched" "Detected in many" 6 "breast cancer: 6.7;cervical cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 25.9;JURKAT: 47.2;MOLT-4: 54.4;SiHa: 92.2;T-47d: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062401, HPA065613" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA062401: AB_2684752, HPA065613: AB_2685519" "unprognostic (8.10e-3)" "unprognostic (8.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-3)" "unprognostic (2.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.11e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.02e-3)" "unprognostic (4.84e-3)" "unprognostic (8.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" 3.2 0.8 2.2 1.4 2.8 2.4 13.9 9.7 4.9 2.4 0.0 1.3 1.6 1.6 1.2 0.9 1.3 2.4 2.5 2.2 1.1 4.3 1.1 2.2 2.6 1.8 1.8 0.7 6.6 0.7 1.9 3.9 2.2 3.8 1.1 1.5 4.4 1.0 1.3 2.7 2.4 0.7 1.4 3.1 6.1 43.2 2.5 1.3 2.4 1.0 1.7 1.8 1.5 4.1 0.3 1.3 0.2 1.4 0.6 0.8 1.4 4.1 1.1 1.8 0.2 25.9 2.6 0.1 4.0 1.8 0.8 0.6 0.5 0.1 1.0 8.5 0.6 0.2 6.1 0.4 0.2 0.4 19.0 0.4 0.4 0.4 0.0 0.9 0.0 47.2 0.2 0.0 0.9 12.5 54.4 2.9 0.4 1.5 0.3 0.0 0.1 0.2 2.1 6.1 0.2 4.5 92.2 13.3 3.3 1.6 82.6 4.7 0.5 0.1 2.8 11.2 0.0 0.0 0.0 0.0 0.0 1.7 5.2 0.7 0.1 0.7 0.8 0.0 0.8 0.2 0.4 0.5 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.0 0.3 0.2 2.2 2.8 9.7 4.9 2.2 1.1 1.8 1.8 2.2 1.4 2.5 4.1 11.5 0.0 1.1 24.5 1.4 1.0 1.1 1.0 0.0 1.9 12.7 9.4 3.6 2.8 6.3 1.8 2.1 0.8 3.0 0.1 1.9 0.9 82.3 0.4 5.0 6.5 0.0 0.0 27.5 3.6 0.4 2.1 2.6 0.5 2.5 1.2 2.9 0.0 0.5 0.0 14.6 0.1 0.0 1.2 0.8 21.8 4.7 1.6 5.4 13.1 1.4 2.3 5.2 28.6 11.1 1.2 1.2 1.9 0.4 1.8 0.3 5.4 8.6 1.1 52.6 1.7 3.8 468.5 92.4 0.6 0.0 0.4 4.1 0.2 0.3 1.2 SYDE1 "7h3, FLJ13511, SYD1" ENSG00000105137 "Synapse defective Rho GTPase homolog 1" Q6ZW31 19 15107401-15114985 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 140.3;Peritubular cells: 42.2;Sertoli cells: 85.5;Syncytiotrophoblasts: 134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013328 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA013328: AB_1848705" "unprognostic (9.99e-2)" "unprognostic (3.73e-2)" "unprognostic (8.17e-3)" "unprognostic (1.65e-2)" "unprognostic (6.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-2)" "unprognostic (2.46e-2)" "unprognostic (2.96e-1)" "unprognostic (5.01e-3)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (5.63e-7)" "unprognostic (1.82e-2)" "unprognostic (7.57e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.27e-4)" 23.3 12.6 7.8 5.7 8.0 0.0 17.6 7.4 7.8 27.6 15.7 28.6 3.8 32.9 4.6 6.6 23.2 5.7 20.8 6.9 7.2 16.3 4.9 18.1 3.5 9.7 8.0 23.5 6.0 2.5 6.7 15.4 7.9 18.2 2.5 1.4 6.1 11.5 5.4 8.6 11.7 10.8 7.8 12.9 13.5 4.7 8.5 0.9 12.4 3.8 1.4 23.9 18.8 7.3 11.2 17.4 9.0 23.9 19.9 18.2 7.1 46.9 33.7 44.4 37.5 4.1 7.0 0.0 30.3 46.5 15.2 7.0 7.0 8.1 24.6 0.3 8.0 1.6 34.2 7.6 37.7 0.1 0.1 32.1 5.9 26.6 12.0 26.8 8.2 0.0 0.0 0.1 33.6 5.9 0.0 0.0 14.7 0.3 17.3 0.0 22.4 0.2 11.1 1.8 0.3 17.8 25.9 15.9 31.6 8.7 1.9 1.2 17.5 107.3 32.8 49.6 50.4 0.1 0.3 0.2 29.3 0.1 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 8.0 7.4 7.8 6.9 7.2 9.7 8.0 7.9 7.8 8.5 7.3 18.6 3.2 1.1 3.6 0.2 2.4 0.8 1.2 1.8 0.3 0.9 3.2 4.1 1.5 0.8 1.8 0.0 7.6 0.0 0.0 0.0 4.7 10.0 0.7 13.6 15.2 0.0 0.0 0.0 0.4 140.3 16.2 0.0 0.5 0.0 12.8 20.0 0.3 3.4 1.7 0.0 0.0 0.0 1.0 2.7 19.3 29.5 0.6 14.2 6.5 0.0 20.0 0.0 1.0 0.2 1.7 0.0 42.2 0.0 0.5 0.0 6.1 0.1 0.8 85.5 10.7 30.8 3.1 0.6 0.3 2.6 134.5 0.4 7.5 0.0 0.2 SYDE2 FLJ13815 ENSG00000097096 "Synapse defective Rho GTPase homolog 2" Q5VT97 1 85156889-85201016 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Cone photoreceptor cells: 54.2;Rod photoreceptor cells: 145.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.6;SK-BR-3: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027138, HPA058378" Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus" No No "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim, Golgi apparatus" "HPA027138: AB_1857686, HPA058378: AB_2683696" "unprognostic (1.68e-1)" "unprognostic (8.90e-2)" "unprognostic (2.34e-2)" "unprognostic (3.43e-3)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (3.84e-3)" "unprognostic (6.47e-3)" "unprognostic (4.39e-2)" "unprognostic (1.85e-1)" "unprognostic (3.88e-2)" "unprognostic (4.05e-1)" "unprognostic (2.96e-3)" "unprognostic (1.57e-1)" "unprognostic (8.76e-2)" "unprognostic (7.51e-2)" "unprognostic (6.69e-2)" 1.1 0.6 0.8 0.9 0.6 0.5 2.0 0.1 1.2 0.8 4.2 4.5 1.5 1.5 0.7 1.1 0.8 2.2 3.2 1.8 0.5 2.5 3.6 3.3 0.3 0.6 0.6 1.6 1.8 4.3 0.7 2.6 0.3 1.3 1.4 7.6 1.9 1.3 0.4 0.7 1.5 2.2 0.6 0.5 1.8 1.6 0.8 0.4 2.5 1.6 0.3 1.9 0.6 0.3 2.1 0.6 0.6 0.8 2.2 0.6 14.6 2.3 1.4 1.4 2.1 4.0 0.7 0.0 0.8 1.5 2.7 3.9 7.3 1.0 2.1 0.9 2.0 1.9 1.7 1.4 2.6 1.2 0.4 1.0 1.2 1.0 0.9 0.9 0.3 1.3 2.4 0.0 1.0 2.9 1.2 0.2 3.7 1.6 0.9 0.0 3.9 0.5 1.0 5.2 0.1 0.0 1.6 8.0 2.4 3.3 1.8 1.6 0.3 1.7 3.8 0.0 2.3 0.0 0.3 0.8 0.2 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.1 1.2 1.8 0.5 0.6 0.6 0.3 0.6 0.8 0.3 3.1 51.3 12.4 9.4 1.1 8.3 8.0 1.7 8.0 6.8 10.0 6.5 24.4 4.3 6.9 1.8 54.2 10.8 0.5 2.5 7.9 1.9 3.1 11.0 2.9 2.1 19.2 3.0 12.6 4.7 4.7 7.8 3.6 5.2 1.3 4.4 3.6 8.4 1.5 0.0 5.2 4.1 2.0 0.3 4.0 1.6 2.1 0.7 19.6 1.9 1.7 9.4 1.0 5.5 0.2 3.6 1.3 2.6 0.7 6.9 8.1 5.8 14.0 145.4 0.0 6.3 5.2 16.6 9.0 8.5 4.5 2.6 3.3 6.6 4.5 4.5 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 SYMPK "SPK, SYM" ENSG00000125755 Symplekin Q92797 19 45815410-45863194 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.6;Late spermatids: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041756, HPA042449" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA041756: AB_10963544, HPA042449: AB_2678003" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (2.59e-1)" "unprognostic (1.59e-2)" "unprognostic (3.11e-2)" "unprognostic (2.33e-3)" "unprognostic (9.93e-2)" "unprognostic (9.78e-2)" "unprognostic (1.23e-1)" "unprognostic (9.16e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-1)" "unprognostic (6.38e-2)" 18.0 17.3 15.5 29.3 17.0 27.4 18.0 12.5 19.8 24.1 11.9 22.5 22.2 25.3 20.1 19.7 23.5 18.0 17.5 14.9 14.1 19.1 21.4 20.6 34.8 18.9 15.6 23.6 19.1 20.7 32.6 25.0 17.1 23.8 14.1 15.7 24.7 16.4 38.5 25.3 22.8 16.1 11.4 28.5 22.9 41.0 16.6 30.0 24.0 18.9 22.8 20.7 19.9 22.7 57.7 101.0 40.4 29.9 39.0 46.8 67.7 44.5 32.0 45.8 51.0 45.8 51.1 101.6 30.2 51.0 25.7 46.2 55.1 49.9 40.0 79.4 62.2 58.7 68.9 47.5 43.7 64.9 65.6 36.1 29.2 49.3 55.4 31.2 47.6 52.6 79.3 64.4 39.4 54.8 61.0 70.3 34.0 50.0 23.9 64.6 46.4 62.6 31.8 102.7 46.0 57.7 55.1 35.5 36.7 40.3 48.4 89.4 53.5 37.1 58.5 28.8 66.9 84.1 173.1 81.5 42.4 42.8 61.8 1.7 3.0 1.5 2.0 2.5 1.9 2.9 1.8 3.2 2.8 4.8 1.5 1.4 3.4 2.7 5.0 5.8 1.4 2.1 15.5 17.0 12.5 19.8 14.9 14.1 18.9 15.6 17.1 11.4 16.6 22.7 14.7 0.0 7.7 34.9 30.2 20.9 18.7 15.6 18.2 21.6 17.4 15.4 7.0 22.8 12.0 25.8 35.5 35.5 20.9 32.7 54.8 21.6 141.6 24.9 29.9 23.4 36.3 26.5 24.6 17.5 34.5 17.5 41.8 27.7 12.7 35.1 26.0 31.8 18.2 21.9 27.1 38.7 10.2 27.0 25.6 146.4 19.3 24.4 14.2 19.7 47.3 11.3 32.0 29.1 28.4 20.4 25.5 21.1 19.8 21.5 30.8 14.9 15.6 27.4 19.7 17.4 20.4 35.3 34.1 14.4 21.3 57.3 21.2 21.9 38.6 20.6 SYNC "SYNC1, SYNCOILIN" ENSG00000162520 "Syncoilin, intermediate filament protein" Q9H7C4 1 32679906-32703596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 106.8;smooth muscle: 54.1;tongue: 73.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 121.0;U-138 MG: 113.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028311, HPA063549" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA028311: AB_2672554, HPA063549: " "unprognostic (3.99e-1)" "unprognostic (6.04e-3)" "unprognostic (2.02e-2)" "unprognostic (7.60e-3)" "unprognostic (1.99e-2)" "unprognostic (5.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.44e-3)" "unprognostic (1.71e-1)" "unprognostic (1.79e-2)" "unprognostic (5.04e-2)" "unprognostic (3.71e-1)" "unprognostic (1.32e-4)" "unprognostic (1.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (8.15e-4)" 10.5 8.5 6.4 15.6 6.1 0.7 5.4 6.7 6.6 9.7 6.1 11.6 6.5 10.9 4.9 17.9 7.4 9.5 17.3 5.8 7.9 2.4 2.2 10.5 6.4 8.3 8.7 3.7 2.6 4.7 0.7 2.5 7.9 13.1 8.7 0.4 9.6 14.6 106.8 2.5 7.3 54.1 9.0 6.2 9.0 9.7 7.4 1.1 4.5 73.4 1.7 12.3 2.9 8.2 8.7 7.0 11.2 19.3 19.4 30.5 6.6 41.9 81.5 28.7 19.6 1.2 24.8 23.9 13.0 121.0 43.4 5.8 1.0 0.7 16.2 12.4 0.8 26.1 22.6 18.0 16.4 33.0 12.0 46.6 2.9 31.6 1.1 86.1 9.0 17.2 19.6 26.2 24.3 4.2 32.0 8.9 5.9 11.2 9.6 34.5 36.5 12.7 32.6 14.2 18.1 1.7 57.1 17.6 21.7 22.2 16.0 10.4 14.4 113.0 19.4 69.4 18.8 11.4 21.1 30.2 39.0 10.4 98.3 5.9 7.7 6.1 6.1 9.6 8.1 6.9 6.9 6.4 9.7 5.2 6.2 7.0 0.9 9.1 9.5 12.3 7.9 12.0 6.4 6.1 6.7 6.6 5.8 7.9 8.3 8.7 7.9 9.0 7.4 8.2 10.6 9.6 9.8 15.7 15.1 22.0 14.2 14.5 8.0 50.2 20.6 7.0 1.0 20.0 14.1 9.2 39.6 9.4 20.7 8.3 5.9 11.7 11.2 12.9 25.0 13.1 7.3 16.0 12.2 5.4 9.3 17.1 0.5 16.3 22.2 12.4 22.9 19.1 5.4 74.0 13.2 8.4 8.2 17.7 23.2 14.8 41.7 7.3 33.8 7.5 11.4 20.0 34.0 15.1 11.6 7.9 7.9 64.3 5.7 16.0 10.7 10.1 6.0 53.9 19.7 16.6 12.8 32.8 36.0 7.2 22.3 5.1 15.3 9.4 12.6 9.4 SYNCRIP "dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1" ENSG00000135316 "Synaptotagmin binding cytoplasmic RNA interacting protein" O60506 6 85607779-85644063 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010895, HPA041275, HPA069241" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "CAB010895: AB_261964, HPA041275: AB_2677389, HPA069241: " "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-2)" "unprognostic (6.22e-2)" "prognostic unfavorable (6.28e-5)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.86e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "unprognostic (4.11e-1)" 60.5 43.2 25.1 80.2 28.0 67.3 55.6 28.1 24.8 51.4 26.0 54.1 48.0 46.1 41.7 75.8 34.0 47.8 45.6 22.8 29.9 53.1 66.7 49.4 88.1 28.9 27.4 36.2 51.9 56.9 19.5 68.5 31.0 44.9 62.7 36.0 41.4 46.5 55.9 43.5 44.0 62.1 27.7 51.3 50.0 38.7 27.6 91.0 87.3 56.0 101.9 81.5 40.8 29.0 209.5 147.5 239.9 157.1 150.8 165.3 162.8 258.6 218.1 244.4 239.9 250.4 132.6 480.0 200.0 262.8 203.1 197.4 331.1 269.0 405.4 175.9 163.9 405.4 152.8 165.2 130.3 497.6 177.7 141.8 179.6 276.4 272.1 138.4 254.9 133.2 451.5 210.0 295.1 243.5 255.2 218.9 231.5 209.4 153.2 364.7 345.5 209.9 236.2 307.1 239.5 184.6 188.5 180.8 128.6 137.2 150.8 360.9 247.4 165.8 142.7 189.8 374.2 138.0 260.5 275.4 165.4 328.7 251.4 1.8 24.7 8.8 30.6 36.2 30.0 21.9 27.1 27.5 37.7 21.2 23.4 27.7 3.0 36.1 41.1 29.0 31.6 24.6 25.1 28.0 28.1 24.8 22.8 29.9 28.9 27.4 31.0 27.7 27.6 29.0 106.9 115.4 119.5 26.4 73.0 148.2 160.9 124.4 83.6 44.5 89.0 82.8 88.9 52.9 126.7 46.0 16.7 101.3 97.2 50.4 54.8 120.7 117.6 105.1 156.2 100.7 56.7 65.6 24.0 99.6 133.3 101.8 79.5 152.1 61.4 81.6 57.5 81.4 96.9 62.2 24.3 78.0 79.3 71.1 67.1 28.7 73.7 92.9 53.4 31.9 90.7 45.1 57.7 32.2 40.9 130.0 45.7 64.3 97.4 133.0 47.7 80.7 84.6 42.2 19.7 158.6 131.8 93.7 65.8 142.4 141.6 118.1 81.6 85.8 106.7 159.8 SYNJ1 "INPP5G, PARK20" ENSG00000159082 "Synaptojanin 1" O43426 21 32628759-32728040 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, RNA-binding" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.9;retina: 48.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 110.9;Inhibitory neurons: 91.5;Oligodendrocytes: 61.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011916 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" Centrosome "HPA011916: AB_1857692" "unprognostic (6.84e-2)" "unprognostic (8.64e-2)" "unprognostic (5.76e-2)" "unprognostic (6.44e-2)" "unprognostic (1.27e-1)" "prognostic favorable (4.43e-4)" "unprognostic (1.45e-1)" "unprognostic (3.73e-3)" "unprognostic (1.63e-1)" "unprognostic (6.22e-3)" "unprognostic (1.84e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.28e-1)" "unprognostic (6.36e-2)" "unprognostic (5.97e-2)" "unprognostic (1.79e-1)" "unprognostic (2.92e-1)" 7.6 6.9 15.0 5.3 22.8 23.8 6.5 1.1 45.9 6.2 3.5 5.6 4.0 5.1 5.1 4.6 5.0 5.2 6.4 22.1 9.8 7.4 5.7 8.0 6.3 19.5 5.6 4.8 4.8 8.4 13.8 9.8 14.8 4.5 5.4 48.4 4.7 3.7 7.7 5.1 6.3 4.9 0.0 7.9 5.0 10.2 8.7 7.1 7.3 6.4 4.8 5.5 5.4 25.9 5.5 2.9 5.0 5.7 8.9 7.1 10.3 11.3 6.2 6.8 5.7 6.1 2.6 2.0 3.8 6.9 8.9 5.0 8.9 6.8 8.4 6.8 8.1 13.8 8.7 3.5 4.8 5.6 11.7 4.1 4.9 12.0 6.1 5.8 10.8 7.3 10.6 11.6 9.0 5.5 5.5 5.1 3.4 6.4 6.0 6.1 11.1 7.4 7.5 4.3 5.6 4.5 14.0 8.4 5.6 6.9 7.8 7.2 11.2 10.0 5.3 8.2 6.4 6.0 7.8 4.4 8.0 10.7 8.7 3.4 2.9 6.9 1.2 5.2 2.0 0.1 1.9 2.0 2.5 0.3 2.2 2.2 9.1 0.5 4.7 1.4 2.6 1.1 15.0 22.8 1.1 45.9 22.1 9.8 19.5 5.6 14.8 0.0 8.7 25.9 10.2 6.4 5.4 22.9 3.9 4.8 1.9 3.1 8.0 24.8 3.8 2.5 10.0 2.8 4.0 1.8 45.9 17.7 7.0 4.8 5.9 2.0 19.9 2.4 4.7 11.9 3.0 5.0 110.9 1.3 9.8 5.3 4.1 3.6 3.8 2.2 11.0 4.2 10.1 10.1 91.5 2.0 0.0 18.6 5.7 11.3 2.8 15.7 1.8 31.9 6.5 21.8 4.1 49.3 61.0 2.8 5.3 4.5 8.6 2.7 6.2 6.5 4.6 45.4 6.6 6.1 5.8 22.1 13.3 6.7 3.3 38.0 9.9 2.8 5.4 4.3 SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 369.6;skeletal muscle: 1296.3;tongue: 502.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 264.7;Distal enterocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cell line enhanced" "Detected in many" "BEWO: 88.4;EFO-21: 72.8;HUVEC TERT2: 72.7;TIME: 178.0;U-87 MG: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: AB_2201163, CAB037325: , HPA034631: AB_10669994, HPA071347: AB_2732179" "unprognostic (2.09e-2)" "unprognostic (7.72e-3)" "unprognostic (3.95e-2)" "unprognostic (2.78e-3)" "unprognostic (3.07e-2)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (1.23e-1)" "unprognostic (5.72e-2)" "unprognostic (2.21e-2)" "unprognostic (6.35e-2)" 91.8 112.1 103.5 21.3 60.7 0.3 48.6 0.0 88.9 23.2 0.8 37.4 31.4 38.7 20.9 31.0 30.8 32.2 369.6 91.2 5.2 60.6 38.5 72.1 10.6 18.2 8.5 34.6 32.9 17.1 21.6 23.8 5.2 46.0 17.5 10.0 21.6 29.1 1296.3 15.4 39.6 38.9 20.6 38.9 34.9 17.0 5.1 6.6 31.1 502.1 11.1 56.8 22.3 34.9 0.5 24.2 0.2 0.3 3.5 3.2 88.4 13.8 18.9 4.6 3.7 21.6 9.7 0.1 72.8 19.9 29.2 8.9 0.1 13.5 1.9 0.2 0.2 0.0 37.4 4.7 19.6 0.0 0.9 3.7 21.3 5.2 3.7 27.5 72.7 0.2 0.2 0.2 4.4 1.6 0.1 0.7 2.8 9.3 11.6 0.5 0.7 0.2 3.4 1.9 8.5 39.3 19.9 21.6 0.7 31.1 1.6 6.6 178.0 17.4 53.2 0.4 3.6 0.8 0.2 1.3 152.5 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.5 60.7 0.0 88.9 91.2 5.2 18.2 8.5 5.2 20.6 5.1 34.9 51.1 35.3 12.2 1.3 4.8 4.6 3.0 32.6 1.8 1.9 6.4 2.5 264.7 27.1 17.0 7.3 2.1 14.8 0.5 70.5 0.0 43.7 1.7 0.4 0.4 56.3 13.8 2.7 22.5 34.5 6.0 19.9 4.6 0.5 0.0 40.9 62.8 40.0 2.1 0.0 5.7 8.4 2.0 10.8 5.1 3.4 2.8 0.9 5.4 6.5 24.0 7.2 0.0 2.5 1.3 35.6 24.4 27.8 0.6 5.7 52.6 4.4 7.6 0.8 46.0 18.0 29.2 1.2 0.8 1.4 2.3 25.9 1.6 8.6 11.8 3.6 SYNPO2L FLJ12921 ENSG00000166317 "Synaptopodin 2 like" Q9H987 10 73644881-73663803 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "heart muscle: 262.3;skeletal muscle: 279.2;tongue: 87.2" "Cell type enriched" "Detected in some" 52 "Cardiomyocytes: 665.1" "Group enriched" "Detected in some" 6 "breast cancer: 1.5;head and neck cancer: 1.4;prostate cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 4.1;HSkMC: 3.2;RH-30: 3.0;SK-BR-3: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055192, HPA057142" Enhanced Supported "Nuclear speckles,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Cell Junctions, Cytosol" "HPA055192: AB_2682732, HPA057142: AB_2683348" "unprognostic (2.75e-1)" "unprognostic (1.58e-1)" "unprognostic (1.20e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (4.54e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-2)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-1)" 0.1 0.5 0.7 0.1 0.7 0.3 3.6 0.8 0.9 0.4 0.1 0.0 0.1 0.1 0.1 11.8 0.1 0.1 262.3 0.7 0.5 0.1 0.1 1.2 0.2 0.7 0.6 0.2 0.4 0.0 0.1 0.6 0.5 3.1 0.0 0.4 4.8 0.0 279.2 0.3 0.0 0.0 0.5 0.2 0.1 0.3 0.6 0.1 0.2 87.2 0.2 0.0 1.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.5 0.6 0.1 0.0 4.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 3.2 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.1 0.1 0.1 0.0 3.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.7 0.7 0.8 0.9 0.7 0.5 0.7 0.6 0.5 0.5 0.6 0.7 0.5 3.2 0.0 0.3 0.9 1.5 1.4 0.0 2.2 1.9 1.0 0.8 665.1 0.0 0.7 0.0 2.1 0.2 0.5 0.0 0.0 0.0 2.6 0.1 0.4 5.0 0.0 0.0 0.3 0.0 0.2 12.6 0.0 0.3 1.3 0.3 0.0 0.4 0.2 0.0 0.9 0.0 0.0 0.6 2.1 1.1 0.9 0.8 1.8 1.0 0.3 0.4 0.0 1.5 1.1 0.0 0.0 0.4 0.3 0.9 0.0 0.2 0.7 1.2 0.0 12.0 5.2 0.8 1.3 0.4 0.4 0.0 0.7 0.2 0.0 1.0 SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 74.2;stomach 1: 127.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 382.2;granulocytes: 130.8;Intestinal goblet cells: 185.9;Respiratory ciliated cells: 138.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.0;MAIT T-cell: 23.7" "Lineage enriched" "Detected in many" 5 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "MCF7: 91.1;OE19: 148.1;RH-30: 175.8;RPTEC TERT1: 124.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" 16.7 9.6 19.3 12.9 24.6 3.3 16.0 8.7 35.7 10.7 11.9 51.7 21.6 9.1 16.3 17.0 7.6 27.8 8.4 29.0 25.1 20.2 6.9 14.8 11.1 26.4 14.0 4.8 2.7 6.4 6.1 18.2 17.9 13.6 74.2 13.3 8.9 9.8 5.1 6.8 25.0 10.2 15.6 10.4 127.7 5.1 13.8 7.1 4.7 2.7 6.8 50.9 7.4 29.1 3.5 8.0 12.2 1.0 2.8 15.4 0.2 30.3 39.4 26.3 59.2 34.7 4.5 0.7 11.1 21.3 38.0 22.3 0.8 2.7 34.5 2.4 0.2 0.0 0.2 0.3 1.8 2.7 0.5 19.6 3.8 56.8 0.8 6.2 0.2 1.0 0.4 0.4 33.6 91.1 0.1 0.9 20.6 148.1 13.6 1.3 175.8 0.1 124.2 46.8 0.3 0.6 6.7 5.4 3.0 10.2 0.6 0.5 0.1 40.8 15.6 25.9 1.5 0.2 0.0 16.1 41.9 0.5 25.7 0.0 0.0 0.0 14.0 0.0 23.7 0.0 2.8 8.4 0.0 0.1 2.3 4.1 0.0 4.6 0.1 1.0 1.1 2.6 19.3 24.6 8.7 35.7 29.0 25.1 26.4 14.0 17.9 15.6 13.8 29.1 7.5 22.4 32.5 15.3 3.0 3.6 11.7 15.8 1.8 10.4 45.4 14.0 2.3 8.6 62.1 68.0 8.4 0.7 45.6 115.2 0.0 9.1 1.2 8.0 2.2 6.4 19.2 4.0 103.9 16.9 0.4 11.5 382.2 2.3 130.8 0.8 5.0 0.5 0.5 1.7 23.2 185.9 2.0 5.9 5.0 0.9 1.8 4.6 10.6 20.6 1.6 14.0 63.8 35.7 91.9 16.5 40.6 30.1 31.6 30.7 16.3 8.6 138.4 8.1 32.9 42.1 59.8 3.6 2.6 2.2 5.7 0.4 50.1 2.3 36.7 60.9 SYTL5 ENSG00000147041 "Synaptotagmin like 5" Q8TDW5 X 38006553-38128819 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 37.2;Inhibitory neurons: 92.0;Intestinal goblet cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.2;MCF7: 5.8;OE19: 8.4;SK-MEL-30: 14.8;SuSa: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026074 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Microtubules, Cytosol" "HPA026074: AB_1857697" "unprognostic (3.60e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (6.68e-2)" "unprognostic (3.09e-3)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.10e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (5.21e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" 0.0 8.2 6.5 0.3 7.2 0.0 2.5 0.0 5.6 5.6 0.1 2.8 2.2 2.2 0.8 3.1 0.4 0.5 1.1 6.7 10.7 1.2 4.4 0.6 0.0 3.4 13.6 0.1 5.8 0.0 0.6 7.4 6.3 0.9 3.2 0.5 2.2 0.4 0.0 0.1 2.4 3.3 2.5 0.0 12.1 0.6 8.6 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 1.2 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 6.2 1.4 0.0 0.0 0.5 2.2 0.7 0.0 0.0 0.0 0.0 0.6 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.7 0.1 0.0 0.1 0.2 0.2 5.8 0.0 0.0 2.5 8.4 0.0 0.0 2.0 0.0 0.0 0.4 3.2 0.0 0.3 1.2 14.8 19.5 0.0 0.0 0.0 0.1 4.7 0.0 3.3 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 7.2 0.0 5.6 6.7 10.7 3.4 13.6 6.3 2.5 8.6 0.9 0.0 0.0 2.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 4.0 1.5 0.3 0.0 8.7 0.0 0.0 3.3 0.0 4.6 0.0 0.0 0.0 0.7 3.6 0.1 3.0 0.0 1.4 0.9 3.6 0.6 37.2 4.0 0.0 1.0 0.4 1.3 0.3 0.0 92.0 20.8 6.1 0.0 0.0 0.0 0.6 0.2 0.0 1.0 0.2 0.0 0.0 0.0 1.1 4.9 3.0 2.6 0.3 0.6 0.6 0.1 3.3 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 8.9 0.1 0.0 0.7 1.0 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134532 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 72.9;Plasma cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 205.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favorable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 29.2 40.3 19.3 37.1 25.6 31.0 27.6 23.2 21.4 30.7 26.7 29.2 26.1 29.1 38.8 28.4 30.6 19.7 25.3 18.6 21.2 24.5 117.5 27.0 60.9 27.9 25.6 30.9 90.9 35.0 38.2 26.2 24.6 28.5 29.0 18.7 55.9 30.3 34.2 29.3 39.4 25.9 22.8 51.2 39.4 24.3 23.4 18.3 43.4 19.0 81.1 25.8 24.8 25.9 32.4 40.6 24.0 32.5 59.8 33.8 23.8 32.8 33.5 40.9 28.8 22.2 55.0 181.0 43.8 42.4 53.8 48.8 26.4 33.3 33.6 28.4 20.0 28.6 46.8 50.2 72.3 43.3 49.6 43.3 59.0 36.1 81.0 36.4 27.0 19.0 36.4 90.1 24.3 47.9 19.1 31.2 26.1 33.6 28.0 31.9 20.3 74.0 25.7 31.5 15.6 32.0 30.4 74.1 53.3 21.0 55.4 28.2 25.9 28.3 18.6 51.2 22.4 178.1 134.2 205.9 38.1 21.8 32.3 16.8 7.4 14.0 7.4 4.7 6.5 21.9 5.2 6.9 4.4 22.6 3.7 3.9 7.0 3.5 4.7 18.4 5.3 6.6 19.3 25.6 23.2 21.4 18.6 21.2 27.9 25.6 24.6 22.8 23.4 25.9 11.5 16.0 21.4 11.1 43.5 17.6 6.9 13.8 12.0 10.7 21.0 15.5 4.0 22.8 20.8 11.0 33.3 14.5 16.4 23.1 1.9 13.6 6.6 14.2 16.2 11.3 8.4 13.2 9.6 18.9 16.5 14.2 17.9 22.1 1.3 10.1 15.0 72.9 15.1 13.5 9.5 33.6 16.2 15.3 13.2 4.1 20.5 10.8 12.4 9.4 10.5 11.0 13.4 13.0 15.8 18.2 11.7 13.2 90.5 14.9 14.0 7.7 15.1 18.7 13.1 11.9 10.7 19.3 13.2 9.7 16.1 42.8 11.7 13.6 18.6 13.8 SZT2 "C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B" ENSG00000198198 "SZT2 subunit of KICSTOR complex" Q5T011 1 43389882-43454247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029012 Approved Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Actin filaments" "HPA029012: AB_10600817" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.14e-1)" "unprognostic (6.61e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.47e-7)" "prognostic unfavorable (2.53e-4)" "prognostic favorable (6.20e-4)" "unprognostic (1.54e-1)" "unprognostic (1.81e-2)" "unprognostic (5.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (1.84e-3)" "unprognostic (8.28e-2)" "unprognostic (7.19e-2)" "unprognostic (2.61e-2)" 6.3 5.3 1.3 4.3 2.5 6.0 6.2 3.2 3.1 6.1 0.8 6.7 3.4 7.2 2.6 5.9 7.0 2.7 5.4 1.1 2.1 4.7 4.4 6.4 4.2 2.9 2.3 8.0 6.5 5.6 8.8 2.7 2.5 6.5 3.4 4.0 6.5 3.2 6.6 7.7 7.9 3.6 0.9 7.1 6.4 9.6 3.0 4.4 9.0 3.9 4.1 6.2 5.8 5.0 4.5 4.4 3.7 3.4 9.1 4.5 5.7 3.7 4.4 4.5 4.1 1.5 5.0 4.1 4.1 5.9 3.2 5.1 3.7 6.3 3.9 5.1 3.4 7.5 8.1 2.7 3.4 6.1 6.2 4.8 4.2 7.7 7.5 5.0 5.2 4.7 3.4 6.8 3.2 2.1 4.1 1.6 3.3 2.7 4.5 4.5 5.1 4.9 2.6 6.2 3.8 3.4 7.8 5.9 4.0 4.8 3.2 8.8 6.5 4.8 6.8 6.4 6.5 7.3 2.8 3.4 4.9 3.8 3.1 1.4 0.5 1.4 0.3 0.4 0.8 0.3 0.1 0.1 0.4 0.3 0.4 0.3 1.1 0.3 0.5 0.9 0.4 0.2 1.3 2.5 3.2 3.1 1.1 2.1 2.9 2.3 2.5 0.9 3.0 5.0 8.3 25.6 19.3 19.6 10.5 1.9 3.5 5.1 6.2 16.8 7.7 7.0 4.8 5.7 6.8 5.5 62.6 6.5 9.2 10.0 0.0 6.1 14.2 5.8 10.1 7.6 3.6 5.5 20.4 6.4 5.2 7.0 13.7 6.9 14.5 19.0 12.8 13.1 5.4 13.5 20.2 7.0 4.1 7.0 3.1 15.8 9.3 9.4 5.4 15.9 11.6 5.8 13.4 11.1 29.1 6.8 3.7 6.0 9.5 4.2 10.5 9.2 8.0 22.2 19.7 9.1 7.1 8.1 8.6 4.2 1.8 5.5 11.4 12.6 7.0 3.8 TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.1;Syncytiotrophoblasts: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" 22.1 15.3 18.2 5.3 18.6 0.2 20.9 23.6 22.7 32.3 28.6 91.5 15.3 26.1 9.2 64.2 32.9 12.9 251.7 19.1 18.8 33.9 18.8 68.7 1.0 16.0 16.9 8.8 25.3 36.4 58.7 21.6 14.8 67.7 20.7 7.2 60.7 13.5 387.1 103.3 35.7 22.0 11.8 4.2 49.1 5.8 16.9 5.7 50.7 159.0 5.7 62.4 49.1 17.7 17.8 55.1 26.5 15.2 7.4 7.4 31.7 7.7 20.7 10.5 7.3 22.7 28.9 0.0 7.0 12.3 12.1 58.1 8.5 20.9 10.9 3.0 4.4 0.0 7.7 43.8 11.5 0.0 0.3 3.4 86.0 5.6 36.6 8.6 22.2 0.1 4.5 0.6 10.4 23.5 0.2 9.9 15.7 27.6 24.8 0.3 15.2 8.5 28.9 26.9 17.6 14.2 12.7 52.0 29.5 7.6 10.2 0.4 20.6 4.7 3.5 11.8 14.5 2.4 11.7 0.3 8.7 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 18.6 23.6 22.7 19.1 18.8 16.0 16.9 14.8 11.8 16.9 17.7 15.5 83.3 94.1 16.3 0.7 33.6 49.7 54.3 33.0 21.6 23.4 14.1 210.1 8.6 70.7 36.8 0.0 53.3 0.4 75.2 1.9 8.2 2.4 88.4 11.0 21.3 30.0 0.0 32.8 14.2 4.4 21.2 38.7 62.8 7.0 0.1 6.1 18.9 6.5 43.7 48.2 38.8 57.0 0.3 4.3 2.6 6.8 1.9 7.2 7.5 0.1 1.1 0.0 80.9 7.6 19.4 47.1 7.5 0.2 49.6 36.5 13.5 84.9 2.7 13.1 27.2 23.7 0.5 8.2 79.5 54.0 228.5 2.6 2.8 41.9 80.5 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TADA1 "ADA1, hADA1, HFI1, STAF42, TADA1L" ENSG00000152382 "Transcriptional adaptor 1" Q96BN2 1 166856510-166876264 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028651 Approved Supported "Nucleoplasm,Focal adhesion sites,Cytosol" No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Focal adhesion sites, Cytosol" "HPA028651: AB_10602476" "unprognostic (9.53e-3)" "unprognostic (2.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.10e-2)" "unprognostic (1.55e-1)" "unprognostic (7.09e-2)" "unprognostic (5.99e-3)" "unprognostic (7.31e-2)" "unprognostic (3.35e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.98e-2)" "unprognostic (3.64e-2)" "unprognostic (2.73e-2)" "unprognostic (6.35e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-2)" 5.1 8.9 9.6 6.1 10.3 19.4 9.2 9.9 12.4 7.7 8.1 8.4 7.7 9.3 7.6 8.3 8.6 5.3 8.6 10.1 9.3 11.6 26.7 6.2 10.4 7.8 8.3 11.0 6.4 10.9 6.2 8.2 8.8 7.9 9.1 17.0 8.1 7.1 9.8 8.0 8.4 7.6 9.2 6.9 7.5 10.8 9.3 13.2 7.5 10.6 10.1 6.6 5.8 11.2 15.7 14.9 27.4 16.3 8.1 10.4 16.2 8.1 9.9 13.2 11.4 13.7 12.5 29.9 15.4 9.6 10.7 11.8 22.3 14.3 10.6 18.9 21.3 9.9 11.9 22.5 12.0 28.3 17.4 7.9 16.3 8.0 19.9 9.6 11.0 22.2 35.9 17.6 10.5 10.9 34.9 22.5 41.6 25.2 16.5 29.1 12.0 37.9 18.0 20.9 17.5 30.6 14.6 18.7 17.5 25.0 25.3 29.3 8.3 10.8 12.4 11.9 17.3 24.9 36.3 56.3 7.5 12.6 10.4 2.9 12.7 13.8 20.7 12.9 22.9 20.2 22.2 23.6 20.7 20.8 27.9 22.3 2.1 27.5 10.4 13.3 23.4 24.7 9.6 10.3 9.9 12.4 10.1 9.3 7.8 8.3 8.8 9.2 9.3 11.2 2.7 9.6 2.7 7.8 8.4 6.1 4.7 3.9 6.2 7.6 4.9 4.6 10.3 2.8 4.1 3.7 8.4 6.1 4.9 4.4 5.9 3.9 4.0 4.8 4.6 4.3 7.2 13.7 9.6 4.0 7.7 4.8 6.6 4.4 5.1 6.1 3.3 20.3 4.2 1.7 10.5 6.1 0.0 5.3 5.1 1.7 4.4 2.6 1.8 3.7 6.9 6.8 4.1 7.5 17.7 3.8 1.7 3.0 7.5 6.2 5.3 7.0 4.3 6.0 0.0 6.1 4.1 5.2 12.9 7.6 5.1 7.3 7.3 1.9 5.9 4.2 TAF1D "JOSD3, MGC5306, TAF(I)41" ENSG00000166012 "TATA-box binding protein associated factor, RNA polymerase I subunit D" Q9H5J8 11 93729948-93784391 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030703, HPA055935, HPA060385" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centriolar satellite" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Mitotic spindle, Centriolar satellite" "HPA030703: , HPA055935: AB_2682974, HPA060385: AB_2684271" "unprognostic (9.91e-3)" "unprognostic (4.38e-2)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "unprognostic (5.40e-3)" "unprognostic (6.46e-2)" "unprognostic (3.68e-3)" "unprognostic (9.70e-2)" "unprognostic (5.24e-3)" "unprognostic (3.55e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (3.17e-7)" "unprognostic (1.95e-1)" "unprognostic (2.51e-1)" "unprognostic (2.34e-1)" "unprognostic (6.37e-2)" 10.0 9.3 2.5 18.2 3.0 16.4 12.6 5.0 6.7 7.7 1.2 9.5 13.7 14.1 9.0 9.5 7.7 15.4 7.1 2.9 3.5 6.8 6.9 8.1 20.6 2.3 0.6 13.8 20.9 5.3 4.9 18.0 2.3 9.9 12.5 8.2 10.1 7.3 8.0 11.4 13.3 9.1 0.5 11.9 11.9 5.5 1.7 10.9 10.1 7.1 13.1 13.8 7.2 7.8 18.2 8.6 17.5 17.9 14.0 47.8 29.2 27.0 11.5 18.4 13.8 28.6 38.8 32.6 34.0 15.6 12.6 44.3 21.5 25.9 21.2 10.6 7.8 34.8 55.6 20.2 16.4 31.9 25.1 19.5 25.8 16.0 35.7 35.0 23.7 22.7 24.2 50.4 22.8 5.0 25.8 66.4 12.1 16.7 9.6 23.3 19.1 30.9 22.7 17.4 10.7 19.5 10.8 38.2 16.5 19.3 32.7 12.4 28.7 26.9 30.5 44.2 28.7 22.9 26.2 32.5 11.2 36.9 10.3 44.2 16.7 28.8 17.3 12.5 17.7 39.1 24.9 19.8 12.0 39.8 28.4 24.1 42.7 18.1 10.8 26.1 18.2 5.2 2.5 3.0 5.0 6.7 2.9 3.5 2.3 0.6 2.3 0.5 1.7 7.8 106.7 89.8 95.5 20.9 246.1 244.2 252.4 66.6 255.0 86.6 129.4 130.9 26.2 134.4 105.3 29.5 39.6 176.0 162.5 94.5 45.0 95.2 19.9 144.9 184.9 121.3 110.2 98.4 41.6 146.3 170.2 147.1 125.4 245.6 104.4 257.2 63.1 54.2 69.3 69.0 38.2 148.0 24.4 103.7 153.6 16.5 128.6 112.0 80.0 24.4 102.1 34.8 89.6 35.2 44.0 110.4 87.5 67.7 162.2 269.2 71.1 101.5 67.7 78.2 72.3 187.4 123.1 49.0 71.5 251.4 203.0 160.9 182.3 119.7 174.1 356.8 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973868-29992261 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favorable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 31.4 36.0 23.4 14.7 21.2 12.7 30.8 18.0 26.1 24.8 11.9 21.8 17.3 25.9 11.1 20.8 22.6 12.0 32.6 23.0 18.9 22.7 17.6 34.0 14.4 21.0 20.0 24.1 19.5 17.4 29.4 19.4 18.9 22.5 8.5 14.3 20.5 13.3 23.4 22.4 24.4 13.3 15.3 33.8 21.8 34.8 20.8 13.2 25.4 12.7 10.5 22.4 21.6 19.0 22.2 41.8 22.4 35.1 25.8 17.1 34.2 40.0 21.1 26.4 24.4 33.6 28.7 23.8 32.8 28.8 18.0 33.9 20.4 20.0 14.1 37.5 43.3 25.8 46.2 34.8 18.7 25.5 47.5 20.0 17.1 28.1 11.2 18.5 44.7 22.4 23.5 23.6 25.8 41.0 29.8 36.0 21.5 16.4 27.6 54.2 32.5 22.2 16.6 20.5 26.1 20.8 22.8 30.2 12.1 14.4 37.5 28.5 62.9 45.0 20.7 32.4 23.6 34.2 23.7 22.1 27.6 28.8 33.7 0.3 0.7 0.4 0.7 0.7 0.8 0.5 0.7 0.6 0.4 0.6 0.4 0.3 1.2 0.5 0.4 0.8 0.9 0.6 23.4 21.2 18.0 26.1 23.0 18.9 21.0 20.0 18.9 15.3 20.8 19.0 52.0 9.6 11.5 21.9 6.3 10.7 4.6 7.5 7.4 14.6 10.5 5.7 9.8 7.2 9.1 9.2 39.6 7.8 7.6 27.0 1.9 8.5 3.9 8.7 9.5 35.3 13.1 3.4 7.9 12.0 6.2 9.7 14.3 8.9 3.8 16.0 47.2 11.8 9.8 10.1 10.7 16.8 12.2 11.2 11.1 4.4 12.5 8.2 7.2 7.5 9.0 8.4 11.3 9.0 12.7 16.1 14.8 12.8 5.9 7.4 27.2 8.0 10.0 21.4 6.6 8.7 8.7 19.7 21.6 9.1 9.7 12.0 9.2 16.0 14.7 7.4 TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Late spermatids: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" 7.4 15.1 17.5 6.0 18.6 25.7 10.0 17.3 22.3 8.2 15.1 8.9 6.4 10.0 9.2 6.1 9.5 6.7 9.1 17.1 17.0 12.4 30.5 11.9 9.6 18.6 17.4 8.1 8.1 13.0 8.5 6.8 18.4 7.4 8.2 24.7 7.6 6.4 35.5 7.7 7.5 9.3 17.4 8.5 7.9 11.1 17.5 12.2 11.5 19.9 8.1 7.6 6.9 19.5 4.9 3.6 6.0 7.0 8.9 6.8 2.5 7.8 6.0 7.4 8.1 4.9 8.5 31.7 8.3 5.0 10.8 4.0 5.2 4.0 9.3 2.9 6.3 6.2 5.0 5.2 8.4 12.6 6.2 4.2 7.7 7.3 5.3 9.1 3.8 19.3 9.7 14.5 7.2 3.5 18.7 10.1 4.0 9.3 8.4 45.0 8.4 5.8 12.0 5.1 10.0 8.0 7.4 6.2 9.5 4.1 11.5 12.3 7.1 6.2 4.1 4.2 10.3 13.9 12.2 24.2 12.4 30.9 7.3 1.1 0.3 0.0 0.2 0.2 0.0 1.0 0.7 0.4 0.5 2.5 0.9 0.7 0.6 0.3 0.3 0.8 0.5 0.3 17.5 18.6 17.3 22.3 17.1 17.0 18.6 17.4 18.4 17.4 17.5 19.5 12.0 32.1 62.6 47.3 20.2 9.1 6.3 4.2 4.0 24.5 15.0 9.9 14.3 10.0 8.7 7.3 114.7 4.2 16.2 11.1 3.9 6.7 79.0 14.2 12.6 12.8 14.4 16.6 42.6 8.2 3.1 10.2 8.6 12.0 2.5 17.5 8.6 46.0 4.2 70.7 43.6 9.8 4.1 10.3 18.9 163.1 9.9 11.1 16.0 45.0 6.5 33.1 8.2 60.8 68.2 9.5 9.4 15.1 8.9 7.1 10.7 8.7 14.4 62.4 6.6 17.0 11.5 33.3 5.7 7.1 8.0 7.0 10.8 16.5 9.0 6.6 TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825317-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 6.2;Excitatory neurons: 14.4;Inhibitory neurons: 14.4;Microglial cells: 4.7;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" 0.2 0.6 0.1 0.0 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain Approved "Nucleoplasm,Actin filaments,Focal adhesion sites" NA NA "Nucleoplasm, Actin filaments" "Focal adhesion sites" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAS2R5 T2R5 ENSG00000127366 "Taste 2 receptor member 5" Q9NYW4 7 141790217-141791367 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;NK-cells: 1.0;Oligodendrocyte precursor cells: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 5.3" HPA053742 Approved "Nucleoplasm,Nucleoli,Cytoplasmic bodies" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli" "Cytoplasmic bodies" "HPA053742: " "unprognostic (5.48e-3)" "unprognostic (3.90e-3)" "unprognostic (6.07e-2)" "unprognostic (8.00e-3)" "unprognostic (7.56e-2)" "unprognostic (4.87e-2)" "unprognostic (1.90e-1)" "unprognostic (1.71e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.13e-5)" "unprognostic (1.13e-2)" "unprognostic (8.29e-7)" "unprognostic (1.29e-1)" "unprognostic (3.28e-1)" "unprognostic (6.92e-2)" "unprognostic (1.39e-2)" 1.4 0.7 1.6 0.8 1.7 0.2 1.7 2.8 1.9 3.3 0.4 1.4 0.5 1.9 2.8 1.4 2.9 0.5 1.2 1.3 1.9 1.5 1.0 1.4 0.7 1.5 1.8 3.8 1.7 0.3 2.7 0.6 1.5 1.9 0.6 1.6 1.8 0.5 1.4 4.3 1.9 0.6 1.2 1.8 1.2 1.8 1.4 0.7 1.8 0.3 0.7 1.5 2.4 2.2 0.2 0.1 0.7 0.3 0.4 1.3 0.8 0.3 0.3 0.2 0.4 1.1 0.2 0.6 0.4 0.1 0.0 0.1 0.8 0.4 0.1 0.3 0.8 0.2 0.6 1.4 0.4 0.9 0.6 1.1 5.3 0.6 1.4 1.5 0.5 0.7 1.4 0.2 0.0 0.9 0.3 2.1 0.7 0.1 0.1 0.1 0.0 1.5 0.2 0.3 1.0 0.6 0.2 0.2 0.1 0.8 0.0 0.2 0.1 0.5 0.3 0.3 0.6 0.9 0.2 0.7 0.4 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.6 1.7 2.8 1.9 1.3 1.9 1.5 1.8 1.5 1.2 1.4 2.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.0 1.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 TATDN3 ENSG00000203705 "TatD DNase domain containing 3" Q17R31 1 212791828-212816830 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032092 Approved Approved "Nucleoplasm,Golgi apparatus,Focal adhesion sites" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Golgi apparatus, Focal adhesion sites" "HPA032092: AB_10671086" "unprognostic (9.81e-2)" "unprognostic (1.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.17e-1)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (9.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.80e-1)" "unprognostic (3.88e-2)" "unprognostic (3.34e-3)" "unprognostic (5.02e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" "unprognostic (3.13e-3)" "unprognostic (2.96e-3)" 13.0 11.3 10.1 10.4 12.4 12.2 10.0 10.1 12.7 6.5 9.3 8.3 6.1 7.1 13.3 7.3 7.7 7.4 19.3 10.6 12.4 16.6 10.3 8.0 12.2 12.2 10.5 8.6 9.4 18.2 8.2 7.3 12.4 6.9 7.7 17.7 8.5 6.9 29.9 6.3 7.2 7.7 10.5 11.1 11.1 10.0 10.4 11.2 11.7 24.1 10.3 8.2 5.5 15.8 12.2 11.9 10.3 15.1 16.7 26.0 23.5 12.9 14.3 10.8 13.1 3.1 17.2 27.4 12.3 12.4 6.0 7.6 13.0 18.2 11.5 17.1 17.0 13.4 10.3 6.3 19.0 33.3 16.3 20.6 12.8 14.3 37.3 11.2 16.1 37.7 28.2 21.7 11.7 5.9 28.4 10.9 13.9 14.9 7.6 16.0 19.3 49.4 11.3 6.3 21.6 18.5 14.5 25.1 30.6 19.2 26.6 19.6 10.1 7.9 10.3 16.4 13.0 19.4 32.9 44.9 20.6 26.8 12.0 26.1 37.2 60.2 12.7 59.3 11.5 39.7 15.8 15.4 45.6 31.0 12.5 14.9 42.8 13.8 64.4 74.6 16.1 22.9 10.1 12.4 10.1 12.7 10.6 12.4 12.2 10.5 12.4 10.5 10.4 15.8 9.1 6.4 16.2 17.3 18.5 4.5 8.1 14.2 3.4 16.1 8.5 8.3 36.6 8.6 8.0 3.7 18.8 14.3 39.7 3.4 41.1 18.1 12.2 10.8 7.6 8.9 10.2 6.5 35.1 16.5 17.5 10.0 6.1 7.8 7.0 10.8 5.3 7.0 18.8 15.2 43.9 5.1 12.2 27.6 8.3 4.0 5.3 20.4 14.2 17.8 31.0 17.8 8.2 23.1 53.6 12.0 6.2 4.9 9.3 6.2 7.3 26.4 12.5 29.6 6.6 8.8 9.2 24.2 17.9 6.6 4.4 9.3 11.1 11.0 5.2 7.0 TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.9;Ductal cells: 351.0;Exocrine glandular cells: 385.9;Pancreatic endocrine cells: 505.8;Paneth cells: 362.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.3;granulocytes: 217.8;monocytes: 78.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Approved "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" 107.3 131.8 62.7 49.2 78.5 16.5 94.4 67.9 67.3 192.9 48.2 108.5 108.8 128.1 33.6 258.5 84.4 90.9 194.8 57.3 58.8 115.0 39.7 94.9 39.3 72.5 73.3 95.9 80.4 23.5 30.9 53.2 69.9 91.7 77.4 3.7 109.7 105.6 28.7 120.4 119.6 70.3 66.2 52.3 136.5 51.2 65.2 44.6 63.6 33.4 49.0 102.8 160.1 80.6 183.1 319.1 68.4 38.5 219.2 175.6 81.3 223.6 184.5 234.0 136.7 135.9 144.5 19.1 159.1 290.8 77.2 282.6 39.1 205.3 90.8 50.7 64.4 25.9 75.8 106.6 191.1 4.3 37.7 267.6 322.5 145.1 68.9 165.3 266.0 50.1 9.6 14.4 280.1 169.4 52.2 15.1 65.9 116.7 112.6 50.0 41.8 16.3 248.6 141.2 14.7 43.2 276.2 116.2 39.4 67.5 125.3 23.2 269.6 195.3 75.2 154.9 230.2 5.7 2.6 5.5 117.4 30.0 190.3 217.8 65.4 120.4 26.9 78.9 22.2 29.2 25.0 26.6 58.7 25.3 17.3 22.7 73.8 20.0 73.6 164.3 36.7 53.3 62.7 78.5 67.9 67.3 57.3 58.8 72.5 73.3 69.9 66.2 65.2 80.6 51.5 60.9 25.8 0.0 19.0 95.3 79.7 229.3 99.6 1.6 51.0 28.2 41.5 92.9 107.6 99.3 0.0 124.7 68.5 395.9 88.0 351.0 16.2 12.8 27.3 77.0 24.6 21.4 0.0 385.9 145.3 72.6 43.8 16.1 26.6 21.2 75.3 11.1 69.8 5.0 0.0 120.0 71.2 35.2 73.2 10.5 174.6 64.0 113.8 0.0 85.5 19.8 26.8 0.0 0.0 505.8 362.8 209.9 5.8 89.0 279.2 185.3 26.8 2.6 39.5 44.1 78.6 8.6 12.8 94.5 76.0 155.6 16.1 92.0 103.0 107.9 TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: AB_10670155, HPA067398: AB_2685833" "unprognostic (3.05e-2)" "unprognostic (7.48e-3)" "unprognostic (4.80e-3)" "unprognostic (8.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.78e-3)" "unprognostic (9.63e-2)" "unprognostic (5.25e-2)" "unprognostic (9.71e-2)" "unprognostic (7.65e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "prognostic favorable (5.28e-10)" "unprognostic (1.56e-1)" "unprognostic (3.50e-1)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" 26.3 42.1 42.7 31.5 41.9 15.9 27.6 38.7 43.9 19.4 50.2 26.4 22.8 20.9 22.9 34.0 23.5 17.0 30.4 42.9 44.9 44.5 27.4 24.4 29.8 49.3 45.6 28.7 19.5 41.9 27.1 23.8 44.8 24.5 26.3 18.5 31.7 20.2 51.6 49.5 26.0 22.9 45.7 34.9 58.5 30.0 48.7 40.1 19.2 41.3 26.9 19.8 22.2 44.2 34.5 36.8 40.4 45.5 32.8 27.4 24.5 27.0 29.3 24.7 21.1 38.3 69.8 54.9 15.6 32.5 62.8 24.5 68.4 61.7 30.0 15.5 22.2 91.8 23.8 40.4 22.7 42.0 197.9 21.3 85.8 23.4 38.3 31.5 23.5 51.2 88.6 19.3 30.2 22.3 64.9 42.5 54.9 41.1 40.8 80.2 53.2 59.9 36.8 23.9 61.6 44.0 22.4 24.1 84.3 31.2 33.3 39.4 23.7 27.2 20.5 24.0 40.3 36.7 91.6 55.7 25.4 53.2 26.6 2.6 13.2 5.6 8.6 8.2 13.1 8.1 9.3 9.3 10.7 8.3 6.9 6.6 40.6 8.6 3.9 11.5 11.9 10.8 42.7 41.9 38.7 43.9 42.9 44.9 49.3 45.6 44.8 45.7 48.7 44.2 8.4 6.4 17.7 22.5 15.5 9.1 7.0 15.8 15.9 10.2 21.1 16.3 4.6 10.0 14.8 14.7 14.6 12.5 16.3 17.7 19.6 11.5 68.0 12.3 10.3 7.8 6.6 7.2 25.6 10.2 7.1 9.5 14.8 11.9 7.6 18.9 8.2 24.4 26.0 25.2 25.1 15.7 10.2 33.6 8.7 41.0 7.2 27.8 19.6 27.2 24.4 13.4 16.5 51.8 27.0 11.8 14.2 8.6 15.4 12.9 12.8 19.8 10.7 6.6 0.0 12.7 7.1 17.7 18.0 19.8 11.9 16.4 16.3 12.5 19.9 10.1 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TBC1D22A C22orf4 ENSG00000054611 "TBC1 domain family member 22A" Q8WUA7 22 46762617-47175699 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 252.9;Oligodendrocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001173 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA001173: AB_1080212" "unprognostic (1.62e-1)" "unprognostic (5.90e-3)" "unprognostic (1.10e-1)" "unprognostic (4.79e-3)" "unprognostic (3.65e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (5.95e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.69e-1)" "unprognostic (9.17e-2)" "unprognostic (4.68e-2)" "unprognostic (4.93e-2)" "unprognostic (4.14e-1)" "unprognostic (1.09e-1)" "unprognostic (2.39e-1)" 13.4 12.3 10.5 14.4 9.9 10.4 11.8 9.0 10.5 11.8 7.9 12.5 14.9 10.5 6.8 18.1 12.1 9.3 12.9 10.4 9.2 13.3 11.0 12.7 19.4 11.3 11.5 9.8 14.7 12.0 11.2 12.0 10.7 9.3 9.5 4.9 14.1 7.8 17.9 17.6 15.0 7.6 9.8 19.1 14.8 7.3 11.0 14.7 12.3 11.3 18.4 11.0 12.3 11.4 19.1 13.0 8.1 9.9 11.6 16.1 9.9 12.8 17.2 14.3 15.3 14.8 14.5 16.6 13.9 19.5 8.9 20.7 7.0 20.0 9.9 7.2 19.6 9.5 11.1 28.6 17.7 20.9 7.4 18.9 23.0 9.8 13.6 17.2 23.7 10.4 6.2 17.4 13.1 9.8 9.3 10.7 8.0 17.9 14.6 11.8 9.5 17.9 16.7 9.7 6.6 12.3 11.8 4.5 20.1 10.0 10.5 13.7 19.5 10.9 15.3 11.5 8.2 11.5 3.9 10.5 27.0 10.6 6.9 2.5 10.7 6.3 6.4 15.5 6.0 11.6 5.9 6.1 12.5 13.0 3.9 4.3 15.5 5.5 18.6 6.1 10.2 6.6 10.5 9.9 9.0 10.5 10.4 9.2 11.3 11.5 10.7 9.8 11.0 11.4 20.3 25.6 18.3 81.0 47.0 6.4 12.1 21.1 21.6 18.6 9.9 7.9 8.6 14.3 20.2 7.3 18.8 24.4 22.7 27.9 11.7 25.8 13.9 20.1 14.2 19.0 3.6 13.5 82.0 23.5 19.6 12.2 39.3 14.5 17.1 13.3 23.2 7.9 33.1 21.9 94.2 16.2 18.3 23.0 16.7 3.5 9.9 32.7 10.6 252.9 39.4 13.7 29.9 76.9 113.2 30.2 25.2 11.7 28.8 10.5 39.4 19.8 15.0 27.3 13.1 12.3 11.8 7.9 10.5 18.5 8.0 29.0 22.7 12.7 18.4 11.8 TBC1D9B "GRAMD9B, KIAA0676" ENSG00000197226 "TBC1 domain family member 9B" Q66K14 5 179862066-179907897 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038350 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nucleoli fibrillar center" "HPA038350: AB_10673170" "unprognostic (5.06e-2)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" "unprognostic (9.53e-2)" "unprognostic (9.45e-3)" "unprognostic (4.25e-1)" "unprognostic (1.06e-1)" "unprognostic (2.84e-1)" "unprognostic (1.10e-1)" "unprognostic (5.08e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (8.22e-2)" 54.9 61.8 53.9 20.8 62.2 22.8 46.3 58.1 51.1 39.3 38.6 34.1 22.8 38.9 12.0 43.9 34.2 23.8 30.9 51.4 50.1 44.8 55.0 31.7 23.9 60.5 59.8 39.0 46.4 27.0 29.2 17.2 61.6 33.6 12.1 9.1 37.0 25.0 45.9 44.4 34.4 21.1 63.4 39.5 35.5 20.5 57.2 13.1 36.3 18.7 15.3 35.1 35.7 65.9 42.7 64.0 27.4 62.4 69.9 49.0 66.8 51.0 47.2 50.1 48.4 43.8 41.9 29.3 60.2 57.8 56.6 39.6 28.3 115.9 9.8 98.0 39.1 26.0 47.3 27.9 41.5 35.1 85.0 50.6 42.6 39.2 18.9 22.6 48.4 55.3 17.7 28.1 39.5 104.2 22.7 24.5 20.3 17.4 36.5 38.7 22.1 27.8 35.1 66.8 40.1 30.4 48.2 54.5 54.9 11.0 45.0 48.8 57.2 71.2 31.9 34.8 45.2 16.8 23.3 22.7 68.0 41.7 51.7 5.0 7.8 5.5 6.1 9.2 4.8 6.3 4.2 4.9 9.3 5.1 3.9 3.5 0.9 4.2 9.2 9.5 4.0 7.1 53.9 62.2 58.1 51.1 51.4 50.1 60.5 59.8 61.6 63.4 57.2 65.9 24.9 22.4 19.2 20.2 19.7 16.6 10.2 14.6 15.4 27.8 23.9 21.6 9.5 12.8 14.0 27.6 8.4 19.8 20.4 28.4 13.7 21.1 2.4 18.2 20.2 21.0 18.0 17.5 32.1 18.0 23.6 21.1 21.9 27.0 11.4 30.0 24.3 35.2 30.7 62.2 23.6 23.9 10.2 33.5 15.7 8.2 32.3 28.6 16.0 15.9 21.4 17.8 24.7 14.6 27.0 25.2 24.3 28.6 16.4 15.3 24.4 22.6 13.3 18.0 26.3 26.7 16.4 11.1 18.5 25.0 15.6 14.1 17.9 57.1 20.5 13.7 TCAF1 "FAM115A, KIAA0738" ENSG00000198420 "TRPM8 channel associated factor 1" Q9Y4C2 7 143851375-143902198 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 251.7;Syncytiotrophoblasts: 521.5;Theca cells: 377.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011732 Approved Approved "Nuclear bodies,Vesicles,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear bodies, Vesicles" "HPA011732: AB_2668526" "unprognostic (1.57e-1)" "unprognostic (7.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.11e-1)" "unprognostic (2.73e-1)" "unprognostic (7.00e-2)" "unprognostic (5.70e-3)" "unprognostic (3.07e-2)" "unprognostic (4.93e-2)" "prognostic favorable (5.93e-4)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (3.95e-3)" "unprognostic (6.45e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.89e-1)" 29.0 46.5 22.7 12.9 51.4 4.7 21.7 15.1 30.3 27.5 2.7 18.8 12.2 32.2 15.2 15.1 22.2 19.3 23.7 29.4 42.7 14.8 29.3 19.0 8.4 15.4 13.4 39.9 19.4 35.1 27.2 81.1 19.8 36.2 20.3 28.0 15.8 19.8 17.5 16.9 15.8 30.6 11.5 11.7 21.7 9.4 31.0 17.1 26.8 55.7 9.0 14.8 13.4 20.1 47.2 29.0 90.1 93.7 57.9 55.7 55.1 54.3 64.9 42.4 56.3 60.5 33.0 0.2 25.2 63.3 54.5 29.7 34.8 35.7 46.5 25.7 26.0 25.7 15.7 54.0 39.7 0.3 16.2 58.2 31.5 50.0 18.4 66.8 53.4 32.2 43.2 4.5 83.2 70.7 42.3 15.9 27.6 52.0 17.4 26.0 60.7 6.2 33.7 37.5 25.6 153.1 55.5 34.2 25.7 63.7 51.5 4.0 48.8 44.6 28.5 42.2 32.7 14.0 19.2 0.4 81.9 7.6 62.3 0.4 1.5 0.9 4.7 1.8 3.3 1.6 2.8 3.1 2.9 1.6 2.4 3.0 0.4 4.4 3.1 1.4 2.3 2.5 22.7 51.4 15.1 30.3 29.4 42.7 15.4 13.4 19.8 11.5 31.0 20.1 36.3 44.8 37.1 30.3 7.3 0.0 15.0 0.0 16.5 47.7 29.4 38.6 43.0 31.5 14.9 3.7 25.0 251.7 15.2 18.7 0.0 30.9 2.4 27.6 62.7 35.1 19.4 22.1 71.2 35.6 43.7 54.6 20.9 40.5 7.6 167.5 34.6 83.6 32.9 30.3 63.1 29.3 0.0 10.5 0.0 3.5 53.1 12.2 0.0 29.0 10.8 27.5 20.6 57.3 43.7 49.9 15.4 56.4 8.4 27.3 20.1 8.9 8.0 26.7 13.1 72.1 53.3 13.3 11.7 14.1 0.0 521.5 10.4 377.5 23.5 24.3 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in many" "Astrocytes: 264.8;Distal enterocytes: 260.0;Extravillous trophoblasts: 231.4;Paneth cells: 211.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 28.1 9.4 47.4 8.6 6.3 7.6 25.0 0.2 12.1 18.9 1.0 22.9 20.4 25.1 6.7 9.9 18.1 9.4 11.3 4.3 46.9 9.9 22.4 13.9 5.4 5.1 98.0 22.9 12.4 11.1 9.6 17.7 1.7 12.3 21.3 4.6 14.5 13.1 8.4 17.2 19.3 16.4 1.6 22.2 23.3 7.6 244.9 5.8 12.9 6.9 3.7 13.8 14.3 3.2 15.0 37.8 40.7 39.6 20.8 13.7 48.5 10.3 20.0 7.1 8.5 24.9 45.3 0.1 11.3 19.4 9.6 10.5 14.0 17.6 9.1 1.7 13.1 10.4 25.2 23.6 22.0 4.2 3.7 24.4 6.3 11.0 18.2 29.7 12.0 8.8 11.0 0.7 8.2 28.0 6.7 2.5 29.2 16.6 21.6 19.0 29.8 6.9 15.2 20.4 0.8 12.4 15.7 15.4 17.0 31.5 10.0 2.2 27.9 6.8 18.7 16.9 21.3 2.6 0.3 0.4 6.5 8.7 14.9 0.4 4.5 0.4 1.5 28.9 0.9 0.0 0.4 1.2 4.1 0.0 0.4 0.6 6.0 0.0 86.6 0.2 0.0 3.5 47.4 6.3 0.2 12.1 4.3 46.9 5.1 98.0 1.7 1.6 244.9 3.2 62.0 22.4 26.5 264.8 3.3 42.6 27.3 35.8 64.9 2.8 53.0 54.9 13.6 52.9 35.5 40.5 6.2 44.2 9.1 260.0 11.7 39.3 8.8 40.1 140.6 46.1 19.8 4.8 35.1 43.6 231.4 90.8 90.2 64.2 0.0 37.6 52.8 74.2 17.5 5.0 16.6 87.7 16.2 99.9 20.6 5.0 59.0 54.6 32.0 107.7 22.4 34.4 5.2 192.5 34.9 59.0 211.1 48.5 6.0 38.4 75.3 16.2 26.8 6.1 92.1 37.3 51.3 9.4 28.9 61.1 39.8 28.5 6.7 13.1 73.9 49.0 TCHP "MGC10854, TpMs" ENSG00000139437 "Trichoplein keratin filament binding" Q9BT92 12 109900264-109983841 "Predicted intracellular proteins" "Apoptosis, Cilium biogenesis/degradation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038638, HPA061543" Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Centrosome, Cytosol" "HPA038638: AB_10670785, HPA061543: AB_2684556" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.42e-2)" "unprognostic (7.94e-2)" "unprognostic (1.59e-2)" "unprognostic (9.75e-2)" "unprognostic (1.15e-3)" "unprognostic (4.63e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.52e-4)" "unprognostic (1.35e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" 6.5 7.3 9.7 8.9 10.6 6.8 6.6 10.9 11.3 10.1 8.1 10.4 7.3 9.1 7.5 15.4 7.6 5.9 8.1 9.4 10.5 7.8 5.6 7.3 11.7 10.4 10.5 8.9 10.9 7.4 6.4 7.6 10.5 8.6 6.8 9.2 10.5 7.9 9.1 27.4 8.2 7.6 9.2 11.8 8.2 9.3 10.7 10.4 8.6 7.0 11.6 9.3 13.8 11.0 27.6 24.0 12.7 15.3 11.0 11.9 17.3 25.6 13.4 21.8 12.1 15.2 9.4 38.2 7.2 14.9 11.8 22.5 14.0 16.0 19.5 20.7 13.8 27.6 15.3 15.0 13.3 38.0 20.4 9.8 19.1 22.9 17.1 13.7 19.7 23.8 30.5 7.5 18.2 18.9 35.0 38.4 15.3 6.6 24.2 31.7 24.9 32.4 9.9 24.2 18.8 19.8 18.5 19.8 18.2 9.0 17.9 27.2 21.8 22.2 15.5 14.3 32.7 21.8 29.5 27.0 23.5 31.0 23.7 0.0 2.7 2.3 3.6 1.7 2.6 2.0 3.2 4.5 2.1 1.3 3.2 2.5 2.7 5.9 3.7 1.5 4.7 3.1 9.7 10.6 10.9 11.3 9.4 10.5 10.4 10.5 10.5 9.2 10.7 11.0 11.7 19.2 21.4 18.9 10.4 9.8 7.7 9.5 8.0 28.9 11.3 11.4 13.2 17.2 12.0 7.3 18.8 11.2 14.3 12.8 9.8 20.7 32.5 23.0 19.1 15.2 14.8 15.4 8.3 15.1 8.4 11.4 10.2 13.2 13.3 15.7 7.9 7.4 11.6 25.2 12.3 10.7 10.2 13.0 7.8 47.6 11.1 11.4 7.2 1.9 14.3 13.9 35.0 10.1 19.4 18.8 14.4 27.8 15.0 9.1 14.2 6.6 33.6 24.0 13.1 19.6 12.6 25.1 33.2 14.8 24.7 7.0 15.9 30.9 12.2 30.7 TCIM "C8orf4, hTC-1, TC-1, TC1" ENSG00000176907 "Transcriptional and immune response regulator" Q9NR00 8 40153482-40155310 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 209.5;Alveolar cells type 2: 882.5;Collecting duct cells: 200.5;Distal tubular cells: 193.7;Ductal cells: 331.6;Glandular and luminal cells: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 48.5;AF22: 134.4;BJ: 51.5;BJ hTERT+: 134.4;EFO-21: 87.5;HeLa: 94.8;RPTEC TERT1: 67.2;SuSa: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027188 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Plasma membrane, Cytosol" "HPA027188: AB_10601150" "unprognostic (8.88e-2)" "unprognostic (2.76e-2)" "unprognostic (7.89e-3)" "unprognostic (7.95e-2)" "unprognostic (7.33e-3)" "unprognostic (1.87e-3)" "unprognostic (2.11e-1)" "unprognostic (2.32e-1)" "unprognostic (2.93e-2)" "unprognostic (8.15e-2)" "unprognostic (6.23e-2)" "unprognostic (8.19e-2)" "unprognostic (2.54e-2)" "unprognostic (5.32e-3)" "unprognostic (1.39e-1)" "unprognostic (9.13e-3)" "unprognostic (4.48e-2)" 91.5 24.2 6.2 42.9 7.4 0.0 64.0 6.0 10.8 134.1 10.6 68.7 30.9 67.7 18.3 22.3 20.3 105.2 130.8 6.5 6.5 252.6 210.0 165.4 18.0 6.5 6.6 44.6 51.5 70.3 18.9 165.1 6.9 67.7 71.1 4.5 176.0 28.3 37.7 13.2 101.4 43.5 6.9 83.3 56.1 4.8 8.6 3.8 53.9 47.9 4.1 255.3 26.2 7.8 0.0 48.5 134.4 0.0 0.0 0.0 0.3 51.5 134.4 0.2 0.6 0.7 0.0 0.0 87.5 1.0 0.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 94.8 21.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.2 67.2 0.1 0.1 0.2 0.2 4.6 0.0 50.4 0.0 0.0 43.6 0.0 1.2 0.4 0.8 1.2 1.7 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 7.4 6.0 10.8 6.5 6.5 6.5 6.6 6.9 6.9 8.6 7.8 209.5 99.3 882.5 0.0 2.8 0.0 0.0 0.0 0.0 0.0 124.9 62.0 0.0 0.0 77.4 200.5 0.0 12.3 1.5 0.0 193.7 331.6 0.0 152.6 90.7 103.2 0.0 0.0 0.0 111.2 26.5 13.5 0.0 397.4 26.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 102.4 0.0 0.0 0.1 0.0 0.0 2.5 8.7 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 4.5 8.1 22.7 0.0 0.0 TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 267.6" "Group enriched" "Detected in some" 4 "B-cells: 282.5;dendritic cells: 210.3" "Cancer enriched" "Detected in many" 18 "testis cancer: 64.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 296 "memory B-cell: 874.7;naive B-cell: 2160.3;plasmacytoid DC: 1099.9" "Group enriched" "Detected in all" 350 "B-cells: 2160.3;dendritic cells: 1099.9" "Group enriched" "Detected in some" 142 "Daudi: 459.4;REH: 599.4;U-698: 616.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: AB_2179419, HPA016604: AB_1857859" "unprognostic (1.27e-3)" "unprognostic (3.12e-4)" "unprognostic (2.61e-4)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (4.75e-4)" "unprognostic (7.70e-2)" "unprognostic (9.67e-3)" "unprognostic (1.03e-1)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-2)" "unprognostic (2.64e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (4.55e-1)" 1.0 0.1 0.1 34.4 0.1 20.3 0.2 0.1 0.1 0.1 0.0 2.4 0.8 0.8 0.6 0.5 0.1 3.6 0.6 0.1 0.1 0.4 0.4 1.0 267.6 0.1 0.1 0.1 0.3 0.0 0.0 0.8 0.2 0.3 2.0 0.0 4.0 0.0 0.1 0.4 14.2 0.3 0.0 56.7 3.4 7.7 0.1 19.1 1.1 0.0 216.0 2.7 0.1 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 459.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 599.4 0.3 0.8 0.0 0.0 0.2 0.2 0.4 0.7 0.1 0.3 0.1 1.0 1.0 0.2 2.8 0.6 0.2 0.5 3.9 616.2 0.2 0.1 0.1 4.6 1.4 1.8 0.5 0.5 1.3 874.7 0.9 0.4 2.2 2160.3 1.5 0.5 3.3 1.3 1.6 1099.9 1.2 92.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 1.3 0.0 282.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 210.3 0.6 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.3 0.0 0.9 0.6 2.8 0.0 0.0 2.7 0.0 3.1 0.0 0.0 0.0 0.2 0.4 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 28.7 60.2 0.0 0.0 0.0 2.7 0.0 0.3 0.0 TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 98.9;Respiratory ciliated cells: 203.7;Spermatocytes: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Vesicles,Actin filaments,Microtubules" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "Nucleoplasm, Vesicles, Microtubules" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" 8.8 14.0 5.6 2.0 5.3 1.0 8.4 9.3 7.5 10.1 18.2 7.1 1.5 9.0 10.7 4.5 15.3 5.6 17.0 5.7 4.5 19.0 9.1 8.3 2.5 4.5 5.0 12.8 10.8 15.2 26.2 4.0 4.4 10.0 0.9 3.0 9.5 6.1 10.3 5.3 4.0 3.6 3.6 4.6 6.9 21.1 5.2 1.3 17.6 1.9 0.8 7.7 7.0 7.0 11.6 11.7 6.7 17.6 24.9 18.0 4.3 6.3 16.2 5.9 4.4 1.2 2.7 2.0 6.9 18.6 7.2 6.1 4.7 4.6 5.0 4.7 8.7 0.3 4.1 3.6 8.6 1.2 1.3 14.8 7.8 7.7 7.9 34.7 3.3 3.0 7.4 2.5 9.7 9.4 0.9 2.2 4.1 3.5 16.7 2.4 2.9 14.6 16.8 1.8 5.5 11.7 13.1 1.6 5.3 5.5 22.7 16.0 4.0 8.2 2.4 3.5 6.0 4.2 2.6 2.6 11.1 1.3 9.3 0.0 2.0 0.0 0.8 3.6 2.2 4.9 1.5 2.5 3.4 9.1 2.2 1.6 6.4 1.0 1.9 4.3 0.5 2.0 5.6 5.3 9.3 7.5 5.7 4.5 4.5 5.0 4.4 3.6 5.2 7.0 6.5 3.2 18.8 25.5 24.0 13.8 28.4 38.4 18.2 10.7 22.8 19.3 13.0 24.3 26.0 16.5 31.3 30.9 5.8 1.0 9.8 24.3 82.7 98.9 29.0 11.5 18.0 1.3 15.0 4.7 8.5 30.5 8.2 9.8 3.8 27.1 9.3 6.9 11.8 3.3 12.1 4.8 32.6 3.8 12.4 18.7 17.1 7.0 23.2 7.5 1.7 30.5 0.0 12.5 9.3 4.2 2.4 28.6 9.6 20.0 0.4 42.5 203.7 34.1 6.6 16.2 18.3 96.9 30.1 8.5 11.2 18.3 4.2 38.1 4.7 16.6 TDRD3 FLJ21007 ENSG00000083544 "Tudor domain containing 3" Q9H7E2 13 60396457-60573878 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 169.1;granulocytes: 152.3;Inhibitory neurons: 128.9;Oligodendrocyte precursor cells: 142.7;Oligodendrocytes: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034925, HPA067153" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB034925: AB_2240523, HPA067153: AB_2732759" "unprognostic (8.52e-2)" "unprognostic (3.19e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.77e-4)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (7.37e-2)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (6.18e-3)" "unprognostic (9.62e-2)" "unprognostic (9.95e-2)" "unprognostic (3.68e-2)" "unprognostic (4.40e-2)" "unprognostic (1.27e-3)" 8.8 8.2 14.2 6.8 18.7 5.8 12.0 18.2 16.4 10.6 12.7 9.9 9.5 10.8 9.9 10.4 9.8 9.2 10.7 11.8 16.0 11.4 9.4 12.5 9.1 17.1 15.5 14.0 14.1 10.9 7.7 6.0 16.6 8.0 11.1 10.9 9.3 7.4 16.7 11.3 8.7 9.2 16.0 8.7 11.2 12.3 17.9 11.9 12.0 18.5 9.2 8.1 7.7 21.2 6.7 7.3 15.3 36.7 5.9 13.3 9.5 7.6 8.4 8.7 5.6 4.9 10.9 16.0 3.0 11.1 7.4 8.9 12.6 11.0 9.4 12.5 10.1 30.4 13.7 9.4 12.0 21.3 15.4 8.9 15.4 5.1 15.1 17.9 12.0 13.3 6.7 9.7 9.5 7.4 19.5 11.4 11.7 24.4 5.5 10.1 7.5 11.0 12.0 8.8 13.8 16.4 10.9 13.2 27.9 10.9 6.8 9.3 10.2 5.4 5.6 6.1 8.5 18.8 17.7 13.7 5.0 11.0 16.7 0.3 1.4 1.6 3.2 2.2 2.3 2.2 3.7 3.7 2.1 1.4 3.0 3.8 0.1 2.1 1.7 4.6 4.5 1.3 14.2 18.7 18.2 16.4 11.8 16.0 17.1 15.5 16.6 16.0 17.9 21.2 24.5 22.4 30.0 169.1 13.8 7.9 9.6 9.3 14.8 30.9 10.8 10.2 44.4 11.5 18.2 11.0 54.2 8.8 18.7 11.5 21.5 13.4 20.9 18.8 24.4 15.9 17.4 7.2 101.1 17.8 10.6 18.5 18.3 15.7 152.3 26.1 11.7 8.8 6.9 20.2 128.9 12.8 12.2 9.5 7.8 24.4 19.0 22.2 19.6 69.3 12.2 12.7 20.6 142.7 168.7 10.6 19.2 18.4 14.6 7.1 12.4 12.3 22.8 30.6 6.6 32.9 12.9 38.9 21.6 14.1 6.7 6.7 20.9 30.6 14.0 8.0 TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.3" "Group enriched" "Detected in many" 4 "Early spermatids: 224.8;Spermatocytes: 82.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075923, HPA077353" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Vesicles "HPA075923: , HPA077353: " "unprognostic (2.01e-1)" "unprognostic (7.41e-3)" "unprognostic (7.25e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (7.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-3)" "unprognostic (2.20e-1)" "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (2.16e-2)" "unprognostic (4.38e-3)" 0.7 1.7 3.3 3.0 5.1 0.2 0.8 7.8 5.4 1.2 1.8 1.0 0.7 0.9 3.4 0.6 0.8 2.2 1.6 4.1 2.6 2.1 2.5 0.7 4.0 3.9 3.2 1.1 1.1 0.4 3.0 1.6 4.1 2.0 0.3 8.9 1.3 0.6 2.3 3.5 0.7 0.4 2.7 2.5 0.8 30.3 3.7 0.0 5.6 0.1 0.1 1.1 0.8 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.1 7.8 5.4 4.1 2.6 3.9 3.2 4.1 2.7 3.7 4.0 0.8 9.6 0.5 3.9 0.0 0.5 0.4 0.1 1.2 11.3 0.4 0.8 3.4 0.0 3.8 7.3 6.2 0.0 0.0 0.0 1.9 0.3 224.8 1.0 2.2 1.2 4.2 0.0 13.6 0.2 0.0 1.0 0.0 0.7 0.0 0.4 0.7 3.0 0.1 5.0 14.7 0.3 0.0 0.3 0.0 33.8 4.1 0.5 3.6 6.5 0.0 1.1 0.0 14.6 17.8 0.1 0.0 4.5 0.0 0.6 0.4 0.4 0.2 7.5 13.1 3.0 0.5 82.7 34.7 0.0 1.6 0.0 0.0 1.4 0.5 0.2 TECPR2 KIAA0329 ENSG00000196663 "Tectonin beta-propeller repeat containing 2" O15040 14 102362941-102502477 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 57.5;Excitatory neurons: 59.1;Oligodendrocytes: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 7.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000658 Enhanced Approved Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nucleoli, Centrosome" "HPA000658: AB_1079191" "unprognostic (6.81e-2)" "unprognostic (1.21e-1)" "unprognostic (3.77e-2)" "unprognostic (2.62e-1)" "unprognostic (4.46e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (5.66e-5)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "unprognostic (1.64e-1)" "unprognostic (5.76e-3)" "unprognostic (3.78e-2)" "prognostic favorable (6.53e-9)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-3)" 5.4 5.1 12.4 5.4 18.8 5.7 5.4 12.1 13.9 6.0 5.6 8.3 3.8 7.9 6.7 4.9 6.4 4.5 7.5 12.9 10.5 4.4 4.1 5.1 2.7 13.0 14.7 5.9 4.5 9.0 7.2 5.7 12.2 6.4 3.2 9.7 10.1 7.2 11.1 5.6 4.7 8.7 10.4 5.7 5.4 10.9 15.4 5.5 5.7 7.8 2.9 7.2 5.0 21.5 4.7 9.4 8.9 7.4 18.0 13.6 4.9 10.4 12.0 10.3 8.6 2.0 3.4 3.5 6.4 10.9 7.6 8.4 6.2 7.8 8.6 13.0 4.1 4.2 4.9 4.1 8.5 2.3 3.9 9.0 6.8 9.3 6.1 9.7 10.2 3.9 2.1 7.8 9.6 8.9 2.1 2.5 3.4 4.9 9.7 5.0 6.2 1.1 5.2 7.8 7.1 6.6 9.0 2.3 5.7 5.7 10.5 3.1 10.6 7.9 2.0 21.4 4.4 8.0 5.1 0.7 7.6 6.1 8.3 0.3 0.5 0.9 0.2 0.3 0.2 0.0 0.2 0.1 0.2 0.1 0.3 0.1 7.3 0.1 0.1 0.1 0.4 0.4 12.4 18.8 12.1 13.9 12.9 10.5 13.0 14.7 12.2 10.4 15.4 21.5 9.1 9.6 6.9 57.5 3.5 2.0 3.1 4.7 8.0 17.0 10.1 8.0 13.0 4.3 5.6 3.7 50.1 7.1 5.7 7.2 5.9 8.2 31.2 7.4 10.3 8.7 4.2 5.7 59.1 7.1 5.7 8.4 5.6 6.3 0.0 8.6 8.2 6.1 4.9 13.5 34.4 3.8 10.2 4.7 3.4 27.9 14.3 12.7 3.6 26.2 8.5 21.6 5.2 28.6 150.4 6.8 2.5 18.8 8.0 4.0 5.9 6.0 7.0 44.7 19.7 9.1 8.3 24.6 15.0 7.7 1.6 6.0 4.6 8.4 4.6 3.2 TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 11.6;Endometrial ciliated cells: 12.0;Exocrine glandular cells: 12.7;Extravillous trophoblasts: 26.6;Hofbauer cells: 14.6;monocytes: 11.9;Pancreatic endocrine cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 66.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039049, HPA039050" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: AB_2676320, HPA039050: AB_10670918" "unprognostic (8.06e-2)" "unprognostic (1.06e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-3)" "unprognostic (8.73e-3)" "unprognostic (2.88e-1)" "unprognostic (1.17e-1)" "unprognostic (6.18e-3)" 5.1 1.6 5.2 4.9 5.5 6.8 4.7 4.1 7.8 4.3 0.5 5.5 5.1 3.8 1.0 6.8 4.6 1.8 4.3 5.8 3.0 4.0 5.4 4.9 5.4 7.0 3.5 2.5 3.0 1.0 5.3 1.6 4.2 4.2 1.6 0.5 4.3 2.3 2.3 8.2 5.4 1.0 3.1 6.8 5.9 4.9 3.6 4.5 5.7 0.5 3.1 3.9 4.5 5.3 17.2 38.9 9.2 13.5 0.8 1.5 24.5 13.4 5.0 15.9 14.7 14.0 31.2 25.6 27.2 2.2 6.2 43.5 3.2 14.0 3.0 29.0 16.0 6.5 22.8 13.3 0.6 12.9 17.9 0.3 4.6 10.6 3.5 2.0 6.4 23.2 10.5 31.2 2.5 66.7 26.9 29.6 11.9 14.6 41.8 21.9 13.8 17.9 4.5 14.3 25.7 15.5 13.7 15.8 9.8 2.0 26.0 12.6 7.8 10.9 18.4 33.4 22.4 17.8 8.2 15.7 13.9 14.8 18.0 0.0 0.5 0.6 0.5 0.9 0.4 0.1 0.8 1.4 0.7 0.3 0.6 0.1 0.1 0.0 0.8 2.4 0.6 0.2 5.2 5.5 4.1 7.8 5.8 3.0 7.0 3.5 4.2 3.1 3.6 5.3 4.8 3.2 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.9 5.3 0.0 0.0 0.6 1.8 0.0 8.0 10.1 0.0 3.9 11.6 0.0 12.0 3.0 4.0 0.0 0.0 0.0 12.7 26.6 3.4 0.0 7.2 0.0 8.1 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 11.9 0.0 0.0 0.0 0.0 14.7 0.0 0.0 4.7 0.0 0.0 2.0 3.6 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.0 4.2 2.5 0.0 0.0 TENT4A "LAK-1, PAPD7, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Terminal nucleotidyltransferase 4A" Q5XG87 5 6713432-6757044 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Breast glandular cells: 13.4;Breast myoepithelial cells: 13.2;dendritic cells: 12.3;Endometrial stromal cells: 15.4;Glandular and luminal cells: 14.0;Granulosa cells: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: AB_2679346, HPA046742: AB_2679781" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-2)" "unprognostic (2.12e-3)" "unprognostic (7.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.62e-1)" "unprognostic (9.78e-2)" "unprognostic (3.10e-3)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.99e-5)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" "prognostic favorable (8.55e-4)" 13.1 8.1 8.4 9.5 8.6 27.6 11.0 16.6 10.1 12.5 5.7 10.0 8.7 11.1 6.4 10.7 11.5 10.0 8.5 8.7 8.1 9.6 20.5 12.8 13.0 6.5 6.5 15.6 12.0 10.0 11.1 9.1 7.0 11.1 7.2 12.5 8.2 8.8 9.3 15.7 12.4 12.2 6.0 13.7 9.6 10.1 7.9 14.6 10.2 12.1 10.4 10.1 11.8 8.9 31.7 20.9 25.4 31.6 17.7 15.6 37.0 21.0 25.7 25.1 28.2 21.9 17.3 23.1 16.1 25.5 28.5 22.9 20.7 16.4 23.1 26.1 14.0 12.0 72.5 12.4 11.0 18.0 17.3 10.7 13.8 28.7 18.4 18.6 15.0 16.9 16.3 29.8 20.8 17.6 24.4 25.3 13.6 9.7 16.6 21.8 21.2 6.0 10.5 17.5 25.1 19.3 50.7 24.1 14.5 13.4 14.5 9.9 13.6 30.6 32.7 27.2 29.8 28.6 12.6 20.4 19.6 16.4 19.2 0.0 0.2 0.2 0.6 0.1 0.6 0.5 0.4 0.4 0.3 0.4 0.5 0.5 0.1 0.1 0.2 1.1 0.6 0.2 8.4 8.6 16.6 10.1 8.7 8.1 6.5 6.5 7.0 6.0 7.9 8.9 19.3 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 13.4 13.2 0.0 0.0 0.0 5.5 0.0 5.3 12.3 0.0 1.9 4.9 0.0 10.7 15.4 4.8 0.0 0.0 0.0 4.4 4.0 4.0 0.0 14.0 0.0 14.5 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 4.2 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 5.6 4.8 10.7 0.0 0.0 TENT4B "PAPD5, TRF4-2, TUT3" ENSG00000121274 "Terminal nucleotidyltransferase 4B" Q8NDF8 16 50152911-50235310 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, rRNA processing" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 82.8;Endometrial ciliated cells: 44.3;Glandular and luminal cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042968, HPA048225" Uncertain Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Nucleoli, Plasma membrane" "HPA042968: AB_2678244, HPA048225: AB_2680319" "unprognostic (1.05e-2)" "unprognostic (4.09e-2)" "unprognostic (1.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.27e-1)" "unprognostic (2.91e-2)" "unprognostic (4.33e-2)" "unprognostic (2.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (3.30e-2)" "prognostic favorable (1.85e-4)" "unprognostic (4.24e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (7.00e-2)" 6.1 6.4 2.4 1.7 2.3 7.1 4.6 3.9 2.6 7.3 3.0 6.9 4.6 6.9 2.3 5.4 6.5 2.0 3.7 2.7 3.0 4.2 8.9 5.0 2.3 2.2 2.4 6.8 4.3 3.9 4.8 2.8 2.2 5.3 1.9 1.4 4.7 1.7 5.4 5.5 5.9 2.5 2.2 4.6 5.5 5.7 3.1 1.7 4.7 2.1 1.9 7.2 6.4 2.7 5.5 1.9 0.6 3.3 3.8 2.0 4.3 3.9 2.3 3.5 1.6 3.4 2.3 6.5 5.6 2.7 1.4 3.6 3.9 2.0 3.1 3.8 4.5 3.6 1.6 5.4 3.8 2.4 4.9 1.9 2.6 2.3 3.3 2.3 1.8 2.1 4.2 1.5 4.1 1.5 3.5 4.6 4.2 1.5 4.5 4.9 4.8 6.9 1.7 0.5 4.0 2.2 4.9 2.7 2.3 1.5 1.5 0.9 3.0 2.1 4.1 4.0 1.9 4.9 3.7 6.9 1.7 2.7 2.7 0.0 0.4 0.0 0.4 0.2 0.1 0.3 0.2 0.5 0.2 0.2 0.3 0.5 0.7 0.2 0.2 0.4 0.1 0.1 2.4 2.3 3.9 2.6 2.7 3.0 2.2 2.4 2.2 2.2 3.1 2.7 17.9 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 17.8 16.3 0.0 0.0 0.0 14.7 0.0 18.1 82.8 0.0 3.9 10.9 0.0 44.3 24.4 6.1 0.0 0.0 0.0 14.9 11.5 6.7 0.0 31.5 0.0 13.5 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.2 0.0 0.0 22.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 18.3 14.9 17.3 0.0 0.0 TEPSIN "C17orf56, ENTHD2, FLJ31528" ENSG00000167302 "TEPSIN adaptor related protein complex 4 accessory protein" Q96N21 17 81228277-81239091 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 9.9;Syncytiotrophoblasts: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063410 Approved "Nuclear membrane,Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear membrane, Nuclear speckles, Golgi apparatus" "HPA063410: AB_2685008" "unprognostic (6.90e-3)" "unprognostic (1.03e-2)" "unprognostic (4.26e-2)" "unprognostic (3.64e-2)" "unprognostic (1.00e-1)" "prognostic favorable (9.96e-4)" "unprognostic (1.16e-2)" "unprognostic (4.85e-2)" "unprognostic (8.52e-2)" "unprognostic (2.29e-1)" "prognostic favorable (6.95e-4)" "unprognostic (4.99e-2)" "prognostic unfavorable (7.31e-8)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (3.58e-1)" "unprognostic (3.16e-3)" 11.4 12.1 8.3 7.4 8.5 13.0 11.3 8.4 12.8 12.9 9.1 14.2 10.8 11.2 4.0 13.3 11.5 4.3 10.2 8.3 8.1 16.6 17.7 12.0 11.0 9.4 8.5 9.3 15.8 3.3 11.4 5.3 8.9 15.3 4.0 1.6 12.0 3.0 10.0 14.6 19.7 4.4 8.3 28.6 15.6 13.3 9.1 10.3 16.0 3.2 5.8 13.5 11.8 8.8 9.5 14.2 5.1 8.6 3.5 5.7 10.0 8.2 4.7 8.5 7.6 9.1 6.8 6.9 4.5 5.5 8.0 11.8 5.3 7.3 3.8 4.1 18.7 5.7 8.1 13.0 5.4 6.0 12.8 3.4 9.1 3.8 4.2 5.9 13.4 9.7 6.7 6.7 5.3 8.4 11.2 15.7 5.7 7.5 11.6 6.9 7.1 7.4 3.3 6.1 6.7 8.5 9.7 11.1 11.5 9.9 9.1 11.3 8.0 11.2 6.6 8.5 8.3 9.4 6.5 5.5 8.3 5.3 5.7 2.4 1.2 4.0 0.8 1.6 0.5 1.2 0.5 0.6 1.3 1.8 0.3 0.4 2.1 0.4 1.0 1.4 0.8 0.8 8.3 8.5 8.4 12.8 8.3 8.1 9.4 8.5 8.9 8.3 9.1 8.8 8.6 9.6 5.5 0.0 2.9 0.0 0.0 0.0 0.0 0.0 6.9 7.1 0.0 0.0 1.3 1.8 0.0 9.9 8.8 0.0 0.0 4.7 0.0 3.2 5.8 3.0 0.0 0.0 0.0 5.3 7.2 2.5 0.0 6.2 6.3 8.6 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 6.0 0.0 0.0 3.3 0.0 0.0 2.3 2.2 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 10.5 3.9 5.1 0.0 0.0 TERB1 "CCDC79, FLJ35894" ENSG00000249961 "Telomere repeat binding bouquet formation protein 1" Q8NA31 16 66754640-66801620 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 12.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079436 Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Cell Junctions, Cytosol" "HPA079436: " "unprognostic (2.15e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (2.29e-1)" "unprognostic (3.91e-2)" "unprognostic (9.75e-2)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" "unprognostic (7.57e-5)" "unprognostic (6.49e-2)" "unprognostic (3.23e-3)" "unprognostic (2.88e-2)" "unprognostic (6.81e-6)" "unprognostic (1.66e-1)" "unprognostic (2.56e-1)" "unprognostic (2.34e-1)" "unprognostic (6.14e-3)" 0.1 0.3 0.7 0.2 0.4 1.5 0.0 1.6 1.0 0.0 1.5 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.0 0.4 0.6 0.1 0.1 0.2 0.3 1.3 0.4 0.1 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.4 0.3 0.0 0.1 0.7 0.1 0.0 0.1 0.2 0.0 12.6 0.8 0.0 0.4 0.0 0.1 0.0 0.0 1.6 0.2 0.6 0.2 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.2 0.8 0.4 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.6 0.1 0.7 0.4 0.0 0.0 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.4 0.2 0.4 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.6 0.3 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.0 0.4 0.2 0.5 0.2 0.3 0.2 0.6 0.3 0.3 0.1 1.9 0.2 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.0 0.4 0.1 0.2 0.8 0.4 0.1 1.1 0.1 0.3 0.7 0.4 1.6 1.0 0.4 0.6 1.3 0.4 0.9 0.1 0.8 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TES "DKFZP586B2022, TESS-2, TESTIN" ENSG00000135269 "Testin LIM domain protein" Q9UGI8 7 116210506-116258783 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 197.1" "Cell type enhanced" "Detected in many" "Early spermatids: 386.6;Glandular and luminal cells: 283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 230.0;hTCEpi: 263.6;SK-BR-3: 267.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015269, HPA018123" Approved Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 34000 "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA015269: AB_1857899, HPA018123: AB_1857900" "unprognostic (9.81e-2)" "unprognostic (5.53e-3)" "unprognostic (4.79e-2)" "unprognostic (1.31e-1)" "unprognostic (4.01e-1)" "unprognostic (6.08e-3)" "unprognostic (1.84e-3)" "unprognostic (4.81e-3)" "unprognostic (8.81e-3)" "unprognostic (6.19e-3)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.60e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" 29.3 7.2 2.7 54.4 2.7 44.1 32.2 3.4 3.6 29.0 10.0 134.7 41.1 105.9 21.7 58.2 45.2 37.4 14.7 2.3 2.9 19.3 10.1 41.0 49.6 6.4 3.5 7.3 20.8 15.3 5.7 25.6 3.4 55.2 69.0 13.4 34.2 197.1 5.1 23.2 47.5 147.6 3.2 30.0 52.1 39.9 4.3 33.5 66.4 8.9 51.3 87.1 41.1 3.0 115.9 24.0 27.0 0.2 11.7 29.7 62.3 58.9 28.9 10.9 10.6 60.4 126.2 0.0 230.0 41.7 1.3 116.9 14.4 87.3 26.4 57.3 46.0 11.5 53.1 30.5 69.9 53.6 0.2 66.4 263.6 37.7 95.0 74.9 31.1 0.0 11.9 39.5 3.0 24.4 0.2 0.7 17.8 134.0 67.4 0.2 0.4 46.0 110.9 44.0 12.4 113.4 85.5 267.1 68.2 77.6 0.3 21.5 52.3 0.6 1.5 86.2 0.7 92.6 48.9 1.3 7.4 27.2 89.3 274.7 79.2 221.5 150.2 132.1 144.7 104.6 113.4 137.6 86.9 95.5 111.0 127.6 41.6 205.1 170.5 20.7 130.4 162.8 2.7 2.7 3.4 3.6 2.3 2.9 6.4 3.5 3.4 3.2 4.3 3.0 40.8 243.6 47.0 0.0 60.4 200.4 196.2 64.8 60.3 2.2 62.2 57.0 16.1 47.1 81.7 36.8 12.5 23.2 121.3 140.8 21.5 110.7 386.6 176.7 29.9 49.0 50.6 17.7 0.1 112.3 78.1 23.6 84.1 283.9 18.9 54.1 25.7 11.9 15.4 1.7 0.1 100.7 34.6 58.0 119.0 112.5 1.8 78.0 28.4 10.3 77.6 24.7 201.8 0.0 0.3 196.8 112.1 0.4 76.3 102.4 65.3 13.6 68.1 13.9 6.6 9.0 42.3 19.1 10.6 55.9 122.7 29.1 79.2 8.8 79.7 135.9 TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 52.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.6;Breast myoepithelial cells: 7.4;Endometrial ciliated cells: 31.5;Glandular and luminal cells: 27.0;Proximal tubular cells: 11.5" "Cancer enhanced" "Detected in many" "breast cancer: 6.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 11.9;T-47d: 23.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "unprognostic (1.99e-1)" "unprognostic (3.97e-3)" "unprognostic (1.34e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (3.22e-2)" "unprognostic (6.71e-2)" "unprognostic (1.76e-2)" "unprognostic (6.99e-3)" "unprognostic (2.54e-1)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (5.27e-2)" "unprognostic (6.39e-2)" "unprognostic (2.99e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" 0.3 0.5 0.7 1.0 0.7 7.4 4.3 0.6 0.6 0.7 0.6 2.5 1.4 0.7 0.7 1.6 1.7 0.4 0.2 0.5 0.8 3.1 0.4 0.4 1.3 1.2 0.7 0.8 1.1 2.1 2.3 0.3 1.2 2.3 2.9 1.5 1.9 1.1 0.0 0.6 1.4 0.4 0.5 1.3 0.9 52.5 0.7 2.1 1.1 0.1 1.1 0.4 0.9 0.5 7.2 3.1 1.3 0.1 0.0 0.0 3.5 1.6 0.8 2.2 1.0 0.9 7.1 2.9 1.6 0.3 0.0 3.4 1.0 1.4 1.7 3.0 2.5 2.1 1.0 0.0 0.0 1.5 11.9 0.0 3.8 0.1 2.2 3.0 0.7 3.4 4.5 5.4 0.3 4.8 0.8 4.2 7.3 3.3 3.1 1.9 0.4 0.8 2.6 0.1 4.4 4.7 0.0 1.5 0.0 3.7 23.8 10.0 2.7 0.2 0.5 0.2 0.1 2.1 2.0 2.8 0.1 4.2 1.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.7 0.7 0.6 0.6 0.5 0.8 1.2 0.7 1.2 0.5 0.7 0.5 0.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.6 7.4 0.0 0.0 0.6 0.0 0.0 1.8 0.7 0.0 5.9 6.3 0.0 31.5 2.6 0.3 0.0 0.0 0.0 4.0 4.7 0.3 0.0 27.0 2.5 4.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.5 0.0 0.0 11.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.1 0.2 0.0 0.0 TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;skin 1: 16.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 88.5;Oligodendrocytes: 86.7;Suprabasal keratinocytes: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA050845: AB_2681256" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" 2.2 1.6 3.7 5.2 2.4 19.7 3.0 6.3 13.7 2.5 0.0 4.1 5.4 2.0 1.4 7.6 1.9 2.5 1.2 9.3 1.7 1.6 3.9 4.1 3.7 2.0 1.5 1.5 2.6 2.0 1.5 4.6 2.2 2.5 4.3 3.6 4.2 1.1 1.2 16.2 6.0 2.1 0.6 3.8 4.3 1.6 2.7 5.8 2.3 1.3 4.1 3.4 4.0 5.8 9.0 8.0 14.5 8.9 1.2 1.3 26.4 1.8 2.4 3.4 2.7 16.6 8.1 14.9 3.5 2.4 1.6 9.4 13.0 5.2 3.6 6.7 5.2 19.2 7.0 5.6 5.1 20.2 11.3 2.0 13.3 4.2 9.9 4.3 5.3 10.3 13.4 4.8 2.0 14.6 10.0 13.0 8.1 7.7 2.7 15.4 9.1 5.2 3.8 16.5 18.1 15.5 4.0 10.3 4.9 5.7 6.6 16.1 6.7 3.7 15.4 1.8 6.8 4.2 2.0 12.7 2.4 13.9 4.9 0.1 0.4 0.2 0.0 0.4 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.2 3.7 2.4 6.3 13.7 9.3 1.7 2.0 1.5 2.2 0.6 2.7 5.8 4.2 6.4 9.0 31.3 6.4 49.5 3.5 4.2 14.8 16.3 8.0 5.8 2.9 2.8 8.0 1.8 20.9 7.0 7.3 10.5 0.0 3.5 4.7 18.8 11.9 6.6 6.0 24.8 88.5 4.4 30.1 3.4 13.7 29.6 2.5 6.2 3.6 6.1 10.1 10.1 45.7 8.0 8.2 26.9 23.2 0.8 0.6 26.9 10.6 54.4 27.1 1.5 2.1 41.7 86.7 6.2 7.7 3.0 4.8 6.2 10.3 1.5 11.9 8.6 0.0 3.8 7.7 0.5 2.6 24.4 68.2 2.5 5.5 2.3 6.9 7.0 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TFAP2D TFAP2BL1 ENSG00000008197 "Transcription factor AP-2 delta" Q7Z6R9 6 50713526-50773033 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "brain: 6.3" "Cell type enhanced" "Detected in single" "Horizontal cells: 1.7" "Cancer enriched" "Detected in single" 10 "lung cancer: 0.5" "Region enriched" "Detected in some" 5 "midbrain: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Region enriched" "Detected in many" 4 "midbrain: 11.8" "Region enriched" "Detected in some" 6 "midbrain: 9.4" HPA048962 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Golgi apparatus, Vesicles" "HPA048962: AB_2680573" 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.3 0.2 0.0 0.0 6.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641473 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 164.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 344.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 31.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033605, HPA044754, HPA068909, HPA077304" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Nuclear membrane, Cytosol" "CAB033605: AB_783105, HPA044754: AB_2679074, HPA068909: AB_2686056, HPA077304: " "unprognostic (4.28e-2)" "unprognostic (9.50e-3)" "unprognostic (1.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.01e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (5.50e-3)" "unprognostic (1.68e-2)" "unprognostic (3.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "prognostic favorable (7.57e-4)" "prognostic favorable (6.17e-4)" "unprognostic (2.30e-1)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" 28.2 23.5 24.3 38.6 24.0 164.0 27.2 24.5 24.4 33.5 32.5 37.8 30.5 27.6 19.4 50.1 32.8 24.6 34.3 24.1 22.8 23.2 25.9 21.8 67.1 27.5 24.4 19.3 18.4 28.5 21.3 40.6 25.3 26.1 42.4 20.2 26.1 30.8 58.2 42.8 32.3 34.3 26.6 30.8 31.3 49.6 26.8 53.4 33.1 59.0 68.3 37.5 30.1 25.7 343.2 82.5 104.4 89.5 138.4 122.7 118.5 187.8 168.7 238.1 218.6 173.3 155.9 314.6 61.3 181.3 130.3 160.3 183.0 167.1 232.2 215.9 212.8 184.4 129.2 109.8 86.8 468.3 155.7 102.1 147.3 151.3 87.4 85.0 162.7 116.2 154.1 82.6 215.5 117.7 207.0 181.4 96.6 322.7 105.0 138.9 93.0 181.1 91.3 129.1 268.2 79.3 84.8 228.8 58.7 75.1 157.9 371.7 114.4 77.2 122.9 165.6 210.8 69.5 92.4 326.4 171.9 285.2 133.2 31.9 3.0 4.6 3.1 3.8 3.4 4.4 4.1 3.7 5.9 3.6 6.3 3.2 3.8 2.3 5.5 3.0 5.3 2.5 24.3 24.0 24.5 24.4 24.1 22.8 27.5 24.4 25.3 26.6 26.8 25.7 21.4 9.6 15.8 12.7 38.8 59.8 32.1 16.1 33.6 10.3 45.6 35.2 26.6 28.6 14.7 29.5 14.6 83.2 33.8 29.8 80.3 12.3 5.5 34.4 28.2 25.8 40.2 344.3 22.5 11.9 128.0 30.8 38.7 31.0 21.0 23.3 34.6 58.7 49.2 6.7 19.5 36.1 12.2 49.1 51.2 10.7 28.6 41.1 35.6 5.6 24.8 14.7 16.5 9.5 10.2 19.0 24.2 28.2 67.3 35.7 29.4 66.5 21.0 22.5 6.6 20.0 32.7 76.7 52.7 74.6 60.0 66.6 32.1 30.3 47.4 35.8 TFDP2 Dp-2 ENSG00000114126 "Transcription factor Dp-2" Q14188 3 141944428-142149544 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.7" "Cell type enhanced" "Detected in all" "Early spermatids: 986.1;Late spermatids: 397.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 216.4;MOLT-4: 423.3;REH: 222.7;U-698: 366.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018396, HPA070399" Supported Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Vesicles, Mitotic spindle" "CAB018396: AB_2287284, HPA070399: " "unprognostic (1.35e-2)" "prognostic favorable (6.32e-4)" "unprognostic (8.08e-3)" "unprognostic (2.90e-2)" "unprognostic (4.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.14e-3)" "unprognostic (2.60e-3)" "unprognostic (5.42e-2)" "unprognostic (1.46e-1)" "unprognostic (5.04e-2)" "unprognostic (2.04e-1)" "prognostic favorable (9.84e-4)" "unprognostic (6.04e-2)" "unprognostic (3.91e-2)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" 18.8 15.1 7.8 9.2 8.9 50.3 18.9 21.2 12.7 12.1 8.2 14.8 22.7 15.3 15.9 13.7 14.7 19.4 26.0 9.0 7.0 29.5 17.3 11.8 10.5 12.5 10.6 23.3 12.4 16.7 13.0 28.4 12.4 19.4 14.0 13.2 12.3 13.7 28.5 11.9 21.3 14.4 7.4 9.5 12.4 69.9 8.2 169.7 21.6 21.3 10.6 11.2 10.2 10.0 32.8 14.7 61.6 49.4 20.3 21.9 134.0 16.3 18.8 25.5 40.2 19.2 32.2 115.8 73.7 18.7 44.6 19.5 15.8 31.2 35.8 46.9 28.5 140.4 21.5 26.0 19.6 43.1 47.8 20.6 22.8 27.8 26.9 23.5 18.3 216.4 53.5 6.8 44.3 25.4 423.3 16.1 49.6 17.2 20.0 222.7 42.2 27.0 29.4 16.5 26.9 25.0 54.5 19.5 29.0 45.3 46.7 21.9 12.0 24.2 21.9 19.8 20.7 20.7 20.5 366.5 19.4 11.4 11.6 69.3 4.0 48.0 28.0 6.9 10.9 14.7 12.8 14.9 9.8 18.7 18.6 22.2 4.4 37.4 10.0 33.7 12.8 12.5 7.8 8.9 21.2 12.7 9.0 7.0 12.5 10.6 12.4 7.4 8.2 10.0 29.7 32.1 30.6 64.0 24.2 25.1 52.1 30.4 43.3 33.0 45.1 36.8 87.6 45.8 30.7 47.8 33.3 235.4 98.5 23.1 93.9 36.8 986.1 63.9 51.1 26.8 38.6 171.9 194.6 26.4 125.2 44.0 15.8 35.8 33.5 84.8 27.8 39.8 27.8 37.0 166.7 27.1 40.7 13.5 15.4 397.5 77.0 27.0 5.4 51.5 14.9 26.1 128.8 61.9 116.6 27.2 25.7 75.2 25.2 36.3 87.5 98.4 43.1 34.5 26.3 96.7 38.6 75.4 75.6 31.3 20.0 99.2 42.9 72.4 42.0 36.0 TFDP3 "CT30, E2F-like, HCA661" ENSG00000183434 "Transcription factor Dp family member 3" Q5H9I0 X 133216662-133218354 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 35 "testis: 4.2" "Group enriched" "Detected in some" 17 "Spermatocytes: 23.5;Spermatogonia: 31.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077304 Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" Cytosol "HPA077304: " "unprognostic (1.57e-1)" "unprognostic (2.17e-1)" "unprognostic (3.22e-1)" "unprognostic (2.91e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 23.5 31.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGDS "SDR2E1, TDPGD" ENSG00000088451 "TDP-glucose 4,6-dehydratase" O95455 13 94574054-94596242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 75.2;U-698: 97.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039927, HPA040857" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA No "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Cytosol" "HPA039927: AB_10795238, HPA040857: AB_10794867" "unprognostic (4.07e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.27e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (2.87e-1)" "unprognostic (9.99e-2)" "unprognostic (1.96e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (5.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-2)" "unprognostic (1.09e-1)" 10.4 9.4 5.3 8.2 5.5 6.0 12.4 5.6 8.2 10.4 6.3 8.0 10.2 8.0 11.8 6.9 9.2 6.8 5.4 4.9 5.6 10.9 30.0 7.1 12.9 5.6 5.4 12.1 10.0 8.1 8.4 10.1 5.9 7.9 9.5 6.9 7.7 7.6 4.1 7.5 9.2 6.7 5.6 9.2 9.1 6.0 5.3 14.1 13.3 4.3 11.0 9.1 6.4 6.6 16.7 7.2 11.6 10.6 17.2 13.5 14.1 15.3 14.9 14.2 13.4 18.9 15.9 26.0 14.8 10.9 8.8 10.4 20.1 11.9 14.9 20.3 7.7 20.7 8.1 18.1 21.0 75.2 13.8 14.9 9.5 8.0 22.8 11.1 13.2 18.9 21.3 8.9 13.3 10.8 20.6 38.4 15.2 26.8 8.3 17.1 11.4 15.9 18.3 7.4 15.9 8.9 11.6 24.2 43.5 19.1 10.2 39.8 12.2 5.6 14.5 8.6 12.6 20.0 11.4 97.5 14.9 26.5 15.5 14.7 5.5 10.8 9.6 6.6 14.9 9.5 11.6 10.7 8.7 7.1 16.8 12.5 1.6 12.1 8.3 7.6 13.8 6.9 5.3 5.5 5.6 8.2 4.9 5.6 5.6 5.4 5.9 5.6 5.3 6.6 7.4 12.8 6.8 8.1 12.8 2.4 9.2 15.9 6.8 4.3 7.8 7.9 5.2 8.6 11.9 7.3 2.1 15.7 12.5 5.8 9.8 11.9 1.2 10.4 8.9 7.0 5.4 3.4 7.7 9.1 17.7 12.9 6.1 6.0 11.4 7.7 7.9 21.4 11.2 1.7 6.7 7.7 8.2 8.8 7.2 1.0 14.3 7.5 8.8 8.4 11.1 7.0 7.2 12.1 10.4 8.9 6.6 8.2 10.7 10.9 10.0 17.6 15.9 4.7 26.3 6.7 8.1 11.9 12.3 8.5 3.7 10.4 11.0 9.2 9.1 9.7 THAP10 ENSG00000129028 "THAP domain containing 10" Q9P2Z0 15 70881342-70892433 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.5;Early spermatids: 12.6;Spermatocytes: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 7 "monocytes: 4.2" "Cell line enhanced" "Detected in many" "U-2197: 40.4" "HPA041416, HPA073220" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 18: U-2197 - ECM organization" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041416: AB_10795592, HPA073220: " "unprognostic (1.00e-1)" "unprognostic (3.51e-1)" "unprognostic (5.42e-2)" "unprognostic (2.43e-2)" "unprognostic (1.34e-1)" "unprognostic (6.15e-2)" "unprognostic (6.25e-2)" "unprognostic (2.16e-2)" "unprognostic (2.99e-2)" "unprognostic (6.47e-2)" "unprognostic (1.55e-3)" "unprognostic (3.71e-2)" "prognostic favorable (3.05e-5)" "unprognostic (1.25e-2)" "unprognostic (2.12e-2)" "unprognostic (7.46e-2)" "unprognostic (9.44e-3)" 1.7 2.2 4.6 1.3 5.2 0.1 1.9 6.1 7.3 2.4 2.4 2.2 2.3 2.1 1.8 1.9 3.2 1.5 4.7 3.9 5.2 3.0 2.1 1.8 1.0 5.1 5.4 3.7 1.9 5.1 1.7 1.8 5.2 3.0 1.9 10.8 1.8 3.1 2.3 1.3 1.2 2.0 5.0 0.9 2.9 3.4 6.3 0.9 3.6 2.3 0.9 2.6 1.4 5.9 7.3 12.6 7.7 9.8 4.1 5.0 0.1 13.5 6.1 11.4 13.5 2.0 9.5 0.0 8.2 3.8 14.3 11.3 16.2 3.7 10.2 0.0 8.3 2.6 6.2 0.9 2.0 0.7 5.2 1.6 5.1 6.5 6.2 7.9 5.8 0.0 0.9 0.0 8.3 5.7 0.0 2.9 11.2 5.2 5.3 0.0 9.9 0.3 5.1 5.9 8.6 8.9 9.3 3.9 6.5 7.5 4.6 6.3 4.3 7.9 5.6 40.4 9.6 3.4 4.3 0.0 5.0 0.9 11.6 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.6 0.1 0.0 0.1 0.0 0.4 4.2 0.0 0.2 0.1 4.6 5.2 6.1 7.3 3.9 5.2 5.1 5.4 5.2 5.0 6.3 5.9 3.5 0.0 0.5 0.0 0.5 1.8 4.1 2.4 1.2 17.5 2.0 2.0 6.1 1.5 2.0 11.0 0.0 0.2 0.0 2.5 9.8 3.0 12.6 5.5 1.9 2.7 3.0 0.4 3.0 1.1 0.3 2.4 1.1 1.1 0.0 2.1 1.4 1.8 1.3 1.7 4.0 1.5 8.2 0.6 1.0 7.8 2.5 0.7 0.0 0.0 0.1 5.2 0.0 1.0 4.7 0.8 5.3 4.9 1.2 2.2 0.6 6.8 5.4 4.6 0.0 1.5 2.9 19.3 2.7 2.6 1.4 0.1 0.2 1.8 2.9 4.2 THAP3 ENSG00000041988 "THAP domain containing 3" Q8WTV1 1 6624866-6635586 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067114 Approved Approved Nucleoplasm,Nucleoli,Mitochondria No No "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Mitochondria" "HPA067114: AB_2685782" "unprognostic (1.82e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.89e-2)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (2.14e-3)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (4.63e-2)" "unprognostic (3.50e-3)" "unprognostic (4.30e-2)" "unprognostic (1.11e-2)" "unprognostic (4.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "unprognostic (2.26e-3)" 17.4 24.7 22.1 6.5 22.3 9.6 17.9 23.1 25.8 23.4 18.9 20.1 7.9 18.8 8.3 15.7 19.4 7.7 28.4 20.9 21.3 27.0 29.0 14.1 11.5 23.7 21.8 22.3 24.0 14.0 19.7 7.4 22.2 22.9 4.5 5.1 16.5 9.9 22.8 17.0 15.1 7.0 21.0 21.6 19.2 16.8 21.9 9.7 19.9 13.4 8.6 18.9 18.2 25.0 13.6 12.8 11.2 16.3 18.2 16.3 10.8 12.0 15.6 31.2 19.4 17.1 8.4 11.9 15.7 13.2 11.6 10.5 17.9 10.7 10.8 20.6 30.1 13.7 18.5 15.5 22.8 9.8 13.6 15.3 13.4 19.7 17.2 19.0 13.6 20.5 14.1 14.9 11.7 9.7 17.2 22.2 9.7 15.8 21.7 16.2 13.6 17.3 14.3 3.2 14.7 16.7 14.6 19.9 28.6 9.3 12.8 17.4 12.4 16.5 9.9 11.4 19.0 16.7 19.3 15.9 13.9 20.9 9.5 16.6 19.4 15.2 25.2 16.2 25.7 22.1 25.0 26.8 24.4 31.0 27.3 23.1 12.0 24.7 12.9 22.2 27.1 20.9 22.1 22.3 23.1 25.8 20.9 21.3 23.7 21.8 22.2 21.0 21.9 25.0 12.1 0.0 7.5 5.5 10.8 14.0 12.0 13.2 9.1 11.1 10.4 14.2 7.2 10.0 6.9 9.2 6.2 16.0 9.7 10.7 19.6 10.5 6.5 9.2 11.8 12.8 7.7 11.0 4.6 10.4 17.5 15.8 5.6 9.0 5.7 17.6 11.7 11.6 15.5 5.0 5.8 10.4 10.2 10.9 15.9 4.7 18.6 7.1 10.6 2.8 19.2 12.2 12.3 5.0 7.9 9.8 13.1 23.3 18.1 21.5 21.1 19.3 12.3 8.8 13.1 13.8 15.8 18.2 18.0 8.7 14.8 16.4 9.3 17.7 13.0 15.6 THAP7 MGC10963 ENSG00000184436 "THAP domain containing 7" Q9BT49 22 20999104-21002196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 162.9;Spermatogonia: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 106.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003083 Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane, Vesicles" "HPA003083: AB_1080264" "unprognostic (6.48e-2)" "unprognostic (2.13e-3)" "unprognostic (3.28e-1)" "unprognostic (4.89e-3)" "unprognostic (1.92e-2)" "unprognostic (1.82e-3)" "unprognostic (5.56e-2)" "unprognostic (1.40e-2)" "unprognostic (2.82e-1)" "unprognostic (2.74e-3)" "unprognostic (1.27e-3)" "unprognostic (2.23e-2)" "unprognostic (9.15e-2)" "unprognostic (2.29e-2)" "unprognostic (1.83e-1)" "unprognostic (3.72e-2)" "unprognostic (3.51e-3)" 16.1 26.9 13.7 5.6 12.9 4.8 18.1 13.7 19.6 23.0 16.0 23.1 7.9 20.4 4.8 15.4 20.9 5.8 19.4 12.6 13.2 20.8 37.8 13.4 8.8 14.1 14.9 21.9 26.9 9.8 39.5 4.2 14.4 29.1 2.5 2.7 19.0 9.2 39.7 19.1 19.0 3.5 13.3 24.2 23.2 35.5 13.9 7.6 20.9 14.4 3.7 21.5 16.6 13.2 23.5 25.0 6.9 11.8 6.0 7.5 14.2 12.1 11.6 15.9 14.7 11.5 13.5 17.2 11.9 7.6 8.4 16.4 6.1 12.1 2.4 17.1 36.4 21.6 18.7 14.9 18.5 22.2 13.4 7.2 15.0 14.0 12.9 7.0 8.4 13.1 106.2 19.8 8.8 29.3 24.4 13.7 9.6 16.0 24.7 19.0 13.6 10.4 8.4 11.8 13.5 11.7 15.1 19.5 21.5 3.2 22.4 14.6 5.5 25.4 19.5 15.4 12.8 27.6 17.4 14.1 27.6 14.3 22.4 1.9 22.1 8.8 27.2 23.9 36.1 50.0 32.8 27.4 21.3 36.9 45.2 36.3 1.9 24.0 25.3 31.6 30.7 24.9 13.7 12.9 13.7 19.6 12.6 13.2 14.1 14.9 14.4 13.3 13.9 13.2 18.7 16.0 25.7 6.2 33.3 19.1 20.3 24.5 14.8 31.5 25.0 30.4 14.8 37.1 18.3 25.8 14.6 31.2 23.8 22.4 64.6 28.2 30.0 16.6 15.7 20.3 22.2 16.2 5.8 38.2 30.1 25.8 20.4 10.6 21.5 21.0 18.5 35.3 27.8 13.5 5.8 22.8 30.5 15.8 11.5 44.0 41.7 14.2 40.9 1.0 27.5 52.0 45.3 3.5 7.2 23.9 19.7 32.4 28.6 31.4 38.4 57.4 22.6 27.1 39.5 22.8 43.5 162.9 119.4 16.7 16.3 29.6 28.8 31.1 21.7 13.2 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THNSL1 "FLJ22002, TSH1" ENSG00000185875 "Threonine synthase like 1" Q8IYQ7 10 25016612-25026664 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Early spermatids: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037585 Uncertain Approved "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" Mitochondria "HPA037585: AB_10696940" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (4.31e-2)" "unprognostic (5.26e-2)" "unprognostic (6.11e-2)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (9.75e-2)" "unprognostic (2.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.71e-3)" "unprognostic (2.08e-1)" "unprognostic (3.21e-2)" "unprognostic (9.84e-3)" "unprognostic (3.06e-2)" 1.7 6.0 4.0 1.8 4.2 0.6 3.6 3.2 4.5 4.1 2.9 2.7 2.6 3.6 4.9 1.9 5.6 2.0 3.7 4.1 4.2 9.7 21.4 1.5 2.8 3.9 3.5 7.3 3.0 5.3 3.7 1.7 4.2 2.9 3.0 4.1 3.4 2.6 4.6 2.2 2.4 2.2 3.9 2.2 2.7 5.9 4.1 3.3 8.3 5.9 2.7 1.8 1.5 4.3 7.1 8.1 5.0 10.0 5.0 6.2 1.3 3.4 1.3 3.7 2.4 5.3 8.8 32.7 10.6 1.6 4.0 3.8 7.2 6.4 3.8 4.5 3.9 12.0 2.2 3.4 5.6 0.0 2.0 3.9 11.6 2.7 5.7 6.4 2.5 13.3 10.4 3.8 8.0 11.1 6.6 2.3 9.2 12.3 3.9 3.5 1.3 14.2 10.6 1.6 8.3 4.7 6.8 6.0 12.3 2.6 6.0 0.6 2.5 4.4 3.9 5.9 3.2 2.7 3.8 0.0 7.3 6.6 3.5 0.1 0.4 0.0 2.9 0.5 5.1 5.0 4.1 3.8 2.2 3.8 9.5 6.3 0.6 10.8 0.7 3.7 2.0 3.1 4.0 4.2 3.2 4.5 4.1 4.2 3.9 3.5 4.2 3.9 4.1 4.3 1.3 3.2 3.2 2.6 3.4 0.6 3.1 5.6 2.8 4.2 2.1 2.9 8.5 1.5 6.1 3.7 0.0 6.1 0.8 0.6 15.6 3.3 29.9 5.1 3.9 1.8 1.2 2.5 4.0 1.3 3.9 2.7 1.5 2.5 0.0 7.8 2.2 9.8 2.1 3.3 5.1 1.8 2.0 0.9 0.8 5.5 2.1 0.6 0.0 4.7 1.5 6.8 0.0 2.0 5.4 1.1 1.0 1.5 0.9 1.8 2.3 11.0 8.7 4.5 0.0 4.3 1.9 8.2 13.6 2.6 1.0 1.0 2.8 11.8 3.5 1.1 THYN1 THY28 ENSG00000151500 "Thymocyte nuclear protein 1" Q9P016 11 134248279-134253370 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038732, HPA038733" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA038732: AB_10697397, HPA038733: AB_2676183" "unprognostic (5.91e-2)" "unprognostic (6.22e-3)" "unprognostic (4.54e-2)" "unprognostic (3.48e-3)" "unprognostic (2.32e-2)" "unprognostic (8.99e-2)" "unprognostic (2.12e-1)" "prognostic favorable (1.01e-5)" "unprognostic (3.32e-2)" "unprognostic (1.99e-2)" "unprognostic (1.02e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" "unprognostic (1.71e-1)" "unprognostic (6.92e-2)" "unprognostic (1.66e-2)" "unprognostic (2.61e-2)" 42.3 40.5 74.2 22.0 75.4 43.3 45.1 74.4 104.9 39.8 68.5 53.9 30.2 43.1 75.8 28.1 47.6 31.1 51.7 75.9 76.2 40.1 57.5 28.3 40.5 72.2 71.3 62.9 32.8 27.9 50.8 22.2 73.2 50.1 44.9 41.3 29.6 54.2 32.3 28.1 36.3 42.3 72.5 36.6 39.4 42.6 74.9 77.1 52.1 38.0 44.5 44.3 33.1 76.6 32.0 19.5 69.8 56.0 65.9 74.7 41.0 26.9 59.2 62.0 58.1 106.8 76.3 60.0 88.6 37.8 66.6 48.9 106.8 82.0 60.5 61.5 30.3 165.5 25.7 97.6 94.3 133.0 52.4 56.9 43.2 73.9 48.2 80.6 98.9 199.0 78.1 28.0 56.5 17.7 155.1 242.8 81.0 127.0 71.0 72.3 51.8 50.6 86.4 55.4 66.4 53.7 55.8 13.6 33.1 50.3 78.2 66.5 52.7 26.6 41.3 24.4 41.7 31.4 35.0 126.9 39.5 170.6 31.5 185.4 89.8 330.3 145.2 108.4 175.6 122.1 152.3 146.8 99.1 96.4 175.4 200.0 47.2 139.1 104.4 131.3 199.8 160.0 74.2 75.4 74.4 104.9 75.9 76.2 72.2 71.3 73.2 72.5 74.9 76.6 41.9 32.1 28.8 8.1 31.1 23.8 42.2 107.4 28.5 28.6 37.5 65.4 52.1 47.1 57.7 36.8 14.6 52.7 33.5 25.5 86.1 48.2 28.2 44.7 33.8 36.9 57.6 40.8 15.3 55.6 52.9 42.3 20.4 23.4 40.5 65.5 37.1 47.9 53.0 28.6 12.0 47.9 75.3 22.2 23.7 16.0 50.4 32.7 40.9 8.4 43.1 65.7 44.3 11.1 11.1 53.2 33.0 48.5 29.8 13.4 49.3 93.3 73.1 23.9 46.0 34.0 51.3 79.1 94.9 31.4 20.6 13.8 44.1 72.7 52.7 31.6 TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 207.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 327.3;Microglial cells: 133.0;Oligodendrocyte precursor cells: 120.6;Oligodendrocytes: 124.6;Suprabasal keratinocytes: 143.3" "Cancer enhanced" "Detected in many" "testis cancer: 15.1" "Region enriched" "Detected in all" 4 "cerebellum: 207.9" "Group enriched" "Detected in many" 5 "classical monocyte: 17.4;intermediate monocyte: 15.3;memory CD4 T-cell: 12.5;myeloid DC: 9.6;naive CD4 T-cell: 16.2;NK-cell: 11.3;non-classical monocyte: 22.0;T-reg: 27.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 34.5;HEL: 34.7;HMC-1: 29.1;RT4: 35.5;SCLC-21H: 32.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 245.9" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: AB_2240410, HPA034853: " "unprognostic (9.59e-2)" "unprognostic (7.44e-3)" "unprognostic (5.64e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-3)" "unprognostic (2.84e-2)" "unprognostic (3.73e-1)" "unprognostic (8.08e-2)" "unprognostic (2.70e-3)" "unprognostic (7.97e-3)" "unprognostic (9.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" 7.2 12.7 40.3 6.6 35.2 2.8 5.4 207.9 49.2 17.8 12.5 5.1 1.7 9.9 3.2 39.7 11.0 4.6 5.5 51.8 26.5 5.5 7.9 5.8 11.1 26.7 33.4 3.3 2.2 0.3 12.9 4.3 36.1 9.0 3.1 8.6 5.6 3.3 0.9 27.2 5.0 11.1 27.5 5.2 2.4 10.5 37.3 18.7 1.9 0.8 11.1 12.1 18.5 28.6 2.9 1.0 21.7 1.3 0.4 4.9 34.5 0.0 0.0 2.7 0.9 0.2 3.9 7.6 1.5 0.5 4.0 5.1 2.5 4.4 4.3 0.6 12.0 34.7 0.7 0.2 0.5 0.0 29.1 2.2 1.5 14.7 5.9 2.6 0.0 11.3 0.0 10.9 11.1 14.7 5.4 0.2 7.1 5.3 9.4 7.0 6.8 0.0 3.3 35.5 32.6 8.1 1.5 11.4 1.3 7.5 4.7 0.1 0.2 3.1 12.5 0.0 1.5 12.3 9.9 6.6 7.2 2.6 24.2 1.5 17.4 0.0 0.5 15.3 3.1 0.1 12.5 2.4 9.6 0.0 16.2 1.0 1.0 11.3 22.0 0.5 27.8 5.9 40.3 35.2 207.9 49.2 51.8 26.5 26.7 33.4 36.1 27.5 37.3 28.6 3.7 3.2 2.3 21.2 1.7 83.7 65.6 3.0 22.8 8.9 4.9 1.9 1.1 1.5 11.8 0.0 2.1 10.1 8.0 1.3 0.0 1.8 11.7 25.2 2.2 31.4 5.4 2.7 43.9 0.7 29.7 11.4 2.0 28.4 24.1 2.0 35.0 5.5 8.1 74.0 327.3 0.4 10.2 22.9 73.4 11.3 34.5 26.3 10.6 133.0 37.3 35.2 4.1 120.6 124.6 1.8 11.6 58.3 3.2 30.8 0.0 0.5 1.2 4.6 6.6 0.9 2.1 1.3 9.8 60.2 143.3 10.7 16.3 82.6 1.2 106.7 TIAM2 STEF ENSG00000146426 "TIAM Rac1 associated GEF 2" Q8IVF5 6 154832697-155257723 "Metabolic proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Early spermatids: 141.5;Excitatory neurons: 74.2;Late spermatids: 347.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.4;non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 65.7;HDLM-2: 27.8;RH-30: 43.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 36.9" "HPA011134, HPA013903" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA011134: AB_1858005, HPA013903: AB_1858004" "unprognostic (9.14e-2)" "unprognostic (5.79e-2)" "unprognostic (1.44e-1)" "unprognostic (6.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (4.36e-2)" "unprognostic (1.89e-1)" "unprognostic (5.74e-2)" "unprognostic (1.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.36e-2)" "unprognostic (1.38e-3)" "unprognostic (1.82e-1)" "unprognostic (8.13e-2)" "unprognostic (6.04e-2)" "unprognostic (1.05e-1)" 0.4 1.2 2.8 0.9 7.1 0.4 1.2 5.4 11.8 1.1 0.0 1.2 8.3 0.8 0.6 0.6 0.8 2.2 2.2 6.1 0.0 0.3 0.3 0.5 1.2 0.4 1.0 0.3 1.3 0.1 1.4 0.5 0.0 2.0 0.8 3.3 1.3 2.7 2.5 0.6 7.9 1.1 0.4 0.7 3.0 13.3 0.8 0.6 5.5 1.7 2.0 2.0 0.7 6.1 8.3 1.5 65.7 6.1 2.9 7.9 0.4 3.2 2.2 3.3 5.5 0.7 4.8 1.1 3.1 6.3 0.9 0.5 2.4 0.0 2.3 27.8 3.3 0.0 1.1 1.9 1.8 0.2 1.7 5.4 0.2 1.1 0.2 2.5 4.7 0.5 0.2 0.1 7.5 0.5 0.7 0.7 4.1 0.1 1.3 8.4 43.3 0.3 0.2 0.2 1.1 14.5 0.1 0.3 0.2 11.9 0.3 0.6 1.5 0.2 15.5 0.4 1.5 0.2 3.6 0.2 0.0 0.3 3.9 0.0 0.0 2.1 0.0 2.0 0.0 2.0 0.1 0.1 0.3 0.7 0.0 0.0 6.4 0.4 9.5 0.0 1.2 0.1 2.8 7.1 5.4 11.8 6.1 0.0 0.4 1.0 0.0 0.4 0.8 6.1 2.9 3.2 2.6 8.8 9.6 3.1 22.5 2.8 1.8 14.3 3.3 5.3 8.3 7.2 2.1 1.8 81.3 1.8 4.3 2.2 0.0 5.3 141.5 8.3 4.9 2.7 0.0 3.6 74.2 3.1 2.6 4.4 6.1 12.1 19.7 6.8 11.0 1.5 1.9 23.5 31.4 3.9 6.1 2.2 2.2 347.4 9.9 5.2 12.4 4.7 9.8 7.6 4.1 28.6 5.1 5.9 5.8 7.9 13.3 9.6 23.9 1.0 3.3 23.9 0.0 7.0 4.3 6.7 7.3 2.1 2.6 0.4 5.0 5.3 3.9 11.6 TICAM1 "MGC35334, PRVTIRB, TICAM-1, TRIF" ENSG00000127666 "Toll like receptor adaptor molecule 1" Q8IUC6 19 4815932-4831712 "Disease related genes, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.9;Paneth cells: 146.3;Urothelial cells: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042460, HPA055421" Approved Uncertain "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA042460: AB_10806240, HPA055421: " "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.81e-4)" "unprognostic (3.52e-2)" "unprognostic (2.88e-2)" "unprognostic (7.60e-3)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.86e-2)" "unprognostic (1.59e-1)" "unprognostic (6.16e-2)" "unprognostic (2.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.30e-2)" "unprognostic (5.02e-2)" "unprognostic (3.53e-2)" "unprognostic (6.48e-2)" 12.8 6.4 4.5 6.7 5.0 15.0 11.2 3.1 7.5 14.0 2.3 13.1 14.4 9.3 1.1 45.6 9.4 7.0 10.3 4.7 4.9 13.9 20.1 16.5 6.9 5.1 5.1 7.3 10.3 2.9 6.1 4.4 4.7 9.4 3.2 0.4 13.5 3.3 19.7 21.5 14.5 3.3 4.6 11.9 15.7 1.8 5.1 2.6 8.2 4.1 4.4 10.1 17.4 4.5 34.9 6.7 0.1 5.8 4.9 6.2 3.1 11.2 11.4 8.8 9.8 6.9 12.2 23.5 6.2 12.9 8.8 23.1 3.2 11.8 3.4 25.4 6.2 5.9 13.7 6.7 13.5 2.1 14.7 10.1 14.4 11.0 8.0 6.8 9.2 8.1 12.9 4.9 4.8 13.0 6.0 1.2 1.0 6.2 26.5 13.2 1.4 15.4 8.0 10.7 4.6 8.5 6.9 20.4 11.4 0.0 9.2 4.9 18.5 10.7 7.3 27.4 17.1 19.6 18.5 16.7 12.5 8.1 8.4 6.8 4.1 1.8 1.7 5.4 1.5 3.4 1.7 2.0 3.6 2.8 1.1 0.7 1.2 1.2 7.1 2.5 2.1 5.1 4.5 5.0 3.1 7.5 4.7 4.9 5.1 5.1 4.7 4.6 5.1 4.5 10.5 6.4 9.6 3.9 12.4 69.3 67.0 20.0 23.9 0.9 19.4 13.6 2.5 21.5 18.5 5.5 0.0 6.3 3.7 156.9 7.9 29.9 0.1 27.0 7.6 14.4 29.2 4.2 3.9 17.5 11.7 11.0 42.3 56.2 10.8 4.6 11.7 13.4 12.8 1.7 3.2 39.2 10.2 14.0 52.6 0.3 3.7 22.1 14.2 1.9 17.7 0.8 7.2 3.0 1.4 51.8 146.3 5.3 18.6 57.5 55.8 9.2 16.3 0.2 6.6 4.6 5.8 0.3 1.4 27.3 71.2 3.4 9.8 3.4 26.2 134.3 TIFA "MGC20791, T2BP, T6BP, TIFAA" ENSG00000145365 "TRAF interacting protein with forkhead associated domain" Q96CG3 4 112274537-112285904 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 86.6;Syncytiotrophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 137.4;U-698: 123.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045889 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA045889: AB_10963785" "unprognostic (2.41e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-3)" "unprognostic (1.05e-1)" "unprognostic (2.25e-1)" "unprognostic (2.48e-2)" "unprognostic (2.14e-2)" "unprognostic (4.60e-3)" "unprognostic (5.26e-2)" "unprognostic (6.44e-3)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (2.99e-1)" "unprognostic (8.49e-3)" 6.4 6.3 2.0 19.9 1.8 40.6 13.7 4.3 2.1 7.7 4.3 7.0 6.7 5.6 2.1 15.6 6.8 7.5 10.7 2.3 2.4 5.2 11.3 10.2 32.2 2.3 2.1 9.3 41.3 11.5 2.1 14.2 2.5 6.7 6.9 2.8 34.8 3.7 3.8 9.3 8.8 5.3 2.1 11.7 10.3 2.1 2.3 15.4 21.1 6.4 34.6 11.6 7.7 2.3 21.9 5.5 7.9 13.4 9.5 7.7 15.9 17.0 32.0 10.6 18.1 2.8 19.1 66.3 13.5 6.8 15.5 6.3 10.9 13.0 22.1 54.1 6.4 6.6 12.4 6.2 6.4 21.2 8.8 10.4 7.0 11.4 12.3 18.0 17.0 18.1 6.8 137.4 14.3 11.0 37.3 11.5 1.6 13.4 7.0 63.7 19.9 44.7 23.6 14.7 18.1 18.6 13.7 28.2 6.6 3.4 12.2 29.9 12.7 16.7 19.8 14.2 13.6 85.3 84.8 123.8 15.7 13.8 12.6 6.8 7.2 4.0 11.1 5.2 18.1 38.2 20.4 19.4 13.2 40.4 9.0 11.6 21.4 17.4 6.8 12.3 33.9 11.3 2.0 1.8 4.3 2.1 2.3 2.4 2.3 2.1 2.5 2.1 2.3 2.3 35.7 19.2 27.4 0.0 44.8 21.3 15.7 27.8 43.9 1.4 31.6 30.9 15.4 12.8 15.7 12.9 0.0 47.9 23.4 4.4 19.6 16.5 0.1 10.0 9.6 31.8 9.0 7.6 1.4 24.4 20.9 22.3 14.8 21.0 3.8 5.4 6.4 10.7 17.8 0.0 0.6 8.4 28.5 13.0 29.7 1.4 9.0 13.1 33.8 2.8 7.1 12.5 11.3 0.5 0.1 11.4 8.0 10.9 86.6 29.2 11.0 9.5 8.8 0.6 6.6 27.2 10.5 2.5 3.8 39.2 26.0 79.4 35.9 5.7 7.0 15.1 TIGD1 EEYORE ENSG00000221944 "Tigger transposable element derived 1" Q96MW7 2 232543883-232550557 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041717 Approved Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies" "HPA041717: AB_2677636" "unprognostic (2.48e-1)" "unprognostic (1.77e-2)" "unprognostic (2.10e-2)" "unprognostic (1.86e-1)" "unprognostic (2.58e-2)" "unprognostic (2.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-2)" "unprognostic (1.20e-2)" "unprognostic (4.40e-2)" "unprognostic (6.86e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (3.77e-2)" "unprognostic (1.85e-2)" "unprognostic (2.77e-1)" "unprognostic (3.21e-3)" 1.8 2.3 6.3 2.3 5.3 6.5 2.7 13.4 7.8 3.2 5.4 2.8 1.9 2.6 2.9 2.8 3.8 1.9 2.4 5.0 4.5 7.4 2.7 2.5 3.4 3.2 2.4 5.7 2.9 1.6 5.0 2.0 4.1 4.4 2.1 10.4 2.7 1.7 4.0 4.2 3.6 1.3 1.5 6.1 3.3 5.2 4.5 3.3 4.7 1.4 2.2 2.8 3.0 9.7 3.1 2.3 4.7 7.5 1.7 2.3 3.6 2.1 1.2 2.6 2.9 2.8 3.6 5.0 1.5 1.6 2.8 3.2 4.1 1.3 3.8 3.0 3.9 4.5 7.7 3.5 1.1 3.6 2.9 2.6 1.2 2.6 1.6 2.5 1.5 6.5 3.6 5.0 2.1 5.3 4.9 8.3 2.8 1.9 2.7 4.7 6.3 2.3 1.5 3.5 6.1 6.0 2.2 2.1 2.3 3.3 3.1 3.9 2.5 4.3 4.5 2.7 2.1 4.8 3.4 4.5 2.5 3.6 2.6 1.6 1.7 1.8 1.9 1.4 1.9 1.7 2.0 1.5 1.1 2.1 3.1 2.5 2.3 1.8 1.5 1.2 1.6 0.7 6.3 5.3 13.4 7.8 5.0 4.5 3.2 2.4 4.1 1.5 4.5 9.7 2.4 9.6 3.9 4.2 5.3 1.3 4.5 2.3 1.8 4.9 2.5 2.2 2.0 1.5 2.9 3.7 8.4 2.2 3.1 1.7 0.0 3.6 4.2 1.0 3.6 1.7 1.2 6.5 4.5 1.5 1.3 3.1 7.7 1.5 0.0 6.4 1.4 0.7 1.4 6.7 5.7 1.5 2.0 1.6 1.7 0.7 4.7 2.4 1.8 1.0 2.8 7.5 5.2 5.0 8.1 2.0 2.4 1.9 5.6 2.6 3.5 1.4 1.7 7.0 6.6 3.7 2.0 3.9 5.7 3.7 2.0 1.4 4.1 4.0 3.0 2.9 TIGD6 DKFZp761E2110 ENSG00000164296 "Tigger transposable element derived 6" Q17RP2 5 149993118-150000654 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044599 Uncertain Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Actin filaments" "HPA044599: AB_10961286" "unprognostic (1.06e-1)" "unprognostic (3.25e-1)" "prognostic favorable (5.35e-4)" "unprognostic (1.94e-2)" "unprognostic (8.18e-2)" "unprognostic (3.00e-2)" "unprognostic (1.30e-3)" "unprognostic (7.48e-2)" "unprognostic (5.96e-2)" "unprognostic (3.85e-2)" "prognostic favorable (5.88e-4)" "unprognostic (1.94e-3)" "unprognostic (1.85e-3)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.33e-3)" "unprognostic (1.18e-1)" 2.6 3.6 2.1 1.7 2.4 1.3 4.7 2.7 2.4 2.5 2.6 2.8 2.2 2.4 5.1 1.7 3.1 2.3 2.0 2.0 2.3 3.6 2.8 2.4 1.9 2.2 2.3 3.9 3.2 11.2 2.6 2.6 2.2 4.1 2.5 3.5 3.1 3.0 1.4 2.7 2.0 2.6 2.1 2.1 2.9 4.0 2.2 2.3 3.0 2.2 2.0 2.4 1.7 2.5 2.1 5.7 3.8 8.2 10.7 8.8 5.9 6.0 6.3 4.6 4.6 3.7 3.7 1.0 5.3 7.1 5.7 3.7 3.4 4.4 5.4 4.7 2.8 1.8 3.1 2.0 9.5 2.6 4.4 9.0 8.3 5.9 7.7 5.4 3.6 4.1 2.5 4.7 5.8 5.0 3.4 1.2 1.5 2.7 4.8 3.9 4.3 2.7 4.4 3.0 2.9 3.8 4.2 6.7 9.1 4.6 7.5 4.5 4.9 3.7 2.8 4.1 4.5 3.5 1.4 2.7 5.9 2.8 5.9 0.0 2.2 1.2 1.5 2.3 1.3 1.4 2.0 1.5 1.9 1.7 4.2 2.6 0.0 3.4 1.3 1.0 2.2 1.5 2.1 2.4 2.7 2.4 2.0 2.3 2.2 2.3 2.2 2.1 2.2 2.5 3.1 12.8 2.7 1.3 2.2 2.2 6.6 2.9 2.2 6.2 5.4 3.7 5.4 4.3 4.7 3.7 0.0 5.2 2.6 2.0 7.9 5.1 1.2 2.9 3.5 2.7 3.0 0.4 1.4 4.7 2.7 3.5 7.1 3.6 3.8 4.6 3.3 1.8 4.2 3.3 1.6 2.6 6.1 1.9 1.9 2.1 4.4 2.6 3.6 2.8 4.8 6.3 1.0 4.5 5.6 4.3 1.9 3.4 3.8 5.7 3.1 7.9 3.6 6.3 0.0 2.1 3.8 20.0 8.7 2.6 1.1 3.6 2.2 6.8 2.0 4.9 TIRAP "Mal, wyatt" ENSG00000150455 "TIR domain containing adaptor protein" P58753 11 126283065-126298845 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054431 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA054431: AB_2682486" "unprognostic (9.30e-3)" "unprognostic (7.39e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.24e-4)" "unprognostic (2.73e-2)" "unprognostic (5.77e-2)" "unprognostic (1.27e-1)" "unprognostic (6.89e-2)" "unprognostic (2.40e-1)" "unprognostic (2.28e-1)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (3.34e-3)" "unprognostic (4.29e-3)" "unprognostic (3.62e-2)" "unprognostic (3.47e-1)" "unprognostic (2.57e-1)" 4.3 4.3 1.5 4.9 1.4 2.9 4.5 3.1 2.4 5.4 3.6 5.3 7.6 4.5 2.5 4.4 5.3 4.5 5.3 1.3 2.1 3.9 6.3 4.2 4.1 1.9 1.8 8.0 4.7 7.2 3.6 4.9 2.1 5.7 5.5 3.1 8.0 6.4 5.3 4.3 6.9 4.7 1.0 5.0 4.3 1.5 1.6 3.1 4.8 4.9 5.1 4.5 3.3 1.1 2.2 7.0 3.7 6.2 6.2 8.5 4.4 5.7 9.3 3.9 3.7 11.0 8.3 5.7 9.6 5.9 6.9 6.2 3.9 4.4 1.5 15.3 3.7 15.4 4.2 7.1 4.9 9.6 7.9 6.4 6.0 7.4 5.1 4.7 6.5 4.6 4.2 12.9 4.6 4.0 0.3 1.5 1.7 15.9 6.3 2.0 1.0 5.4 3.1 7.8 4.6 5.8 6.8 6.7 4.6 4.8 18.2 4.9 6.5 2.2 2.1 4.5 4.3 3.6 5.6 4.2 3.4 7.5 7.0 5.3 5.8 2.9 4.0 4.5 3.7 2.1 3.1 4.2 4.6 3.8 2.5 2.4 4.9 2.6 3.2 3.2 3.5 3.7 1.5 1.4 3.1 2.4 1.3 2.1 1.9 1.8 2.1 1.0 1.6 1.1 1.7 6.4 2.6 2.3 3.7 0.4 1.8 2.0 4.0 3.5 2.7 2.0 1.3 2.8 2.8 3.7 0.0 3.4 2.2 4.2 0.0 3.3 0.0 1.1 2.3 3.2 1.2 0.8 3.7 4.0 4.9 2.7 2.0 1.7 1.3 2.0 2.5 4.8 5.2 3.3 5.0 3.9 2.0 4.4 0.8 0.3 4.7 3.7 1.8 3.7 2.1 3.6 4.1 3.0 1.8 3.6 8.1 4.5 9.2 2.0 6.5 2.2 1.6 2.5 0.0 2.0 2.5 0.1 0.6 3.5 0.1 2.6 4.2 2.3 2.4 1.5 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: AB_1857760" "unprognostic (9.71e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (1.96e-1)" "unprognostic (5.55e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.21e-4)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (7.83e-2)" "unprognostic (8.83e-3)" 125.7 62.7 31.1 84.7 42.1 79.2 79.4 39.3 31.1 80.0 43.1 196.2 36.5 151.8 25.3 78.0 102.9 53.2 81.2 26.2 34.9 47.3 42.3 91.8 63.1 50.8 41.9 66.0 33.1 41.6 36.7 70.4 49.7 72.6 41.4 7.7 42.5 111.4 70.9 46.7 77.9 145.4 41.5 89.7 91.8 23.3 44.9 61.1 49.0 55.8 52.7 147.7 66.3 44.6 63.4 103.8 62.7 86.9 210.8 158.7 71.4 171.2 186.8 162.9 146.4 86.3 27.4 76.5 55.5 319.0 103.0 33.3 74.2 106.9 118.3 172.8 48.0 173.0 132.1 77.4 130.6 105.8 276.2 193.4 50.2 240.1 112.7 223.7 253.4 64.7 60.2 76.0 218.5 27.8 71.5 27.8 51.3 28.4 78.8 95.0 36.6 44.8 81.4 49.8 14.1 59.6 83.7 46.3 53.4 56.5 39.3 72.6 308.5 257.8 99.6 80.0 140.6 26.2 27.6 51.7 199.9 55.9 238.4 6.0 5.9 7.3 5.4 6.1 4.4 2.6 3.1 4.1 4.3 2.3 1.4 3.1 10.0 4.1 8.1 5.4 2.3 6.9 31.1 42.1 39.3 31.1 26.2 34.9 50.8 41.9 49.7 41.5 44.9 44.6 123.2 109.0 66.9 11.4 99.8 40.1 69.4 43.5 42.7 11.7 40.3 61.3 134.1 31.5 55.7 53.3 10.4 44.3 186.3 43.8 23.5 94.3 47.2 36.0 156.9 106.8 34.1 127.0 7.7 61.9 82.6 103.9 51.0 73.0 206.6 72.0 93.9 54.7 112.4 15.2 7.6 29.0 26.4 196.9 91.0 26.4 99.4 323.4 23.2 21.5 174.1 33.0 288.4 4.5 9.1 107.7 33.2 128.6 61.4 58.4 40.6 62.8 34.3 17.6 203.8 126.5 267.9 32.0 28.5 47.4 26.6 58.8 143.8 89.4 28.9 46.4 TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.2" "Cell type enhanced" "Detected in many" "Club cells: 23.3;Glandular and luminal cells: 25.6;Kupffer cells: 29.5;Microglial cells: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.3;non-classical monocyte: 12.4" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.3;monocytes: 30.8" "Cell line enhanced" "Detected in some" "A-431: 2.1;HaCaT: 3.2;OE19: 1.8;SK-BR-3: 2.0;T-47d: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" 3.5 1.9 2.6 4.7 2.2 0.5 8.6 2.5 2.4 6.0 2.3 2.0 1.6 2.1 2.6 4.9 5.1 4.5 1.7 2.3 2.7 4.1 1.6 6.2 4.3 3.7 3.5 20.2 4.0 4.4 0.7 3.4 3.6 3.3 2.1 0.7 10.3 2.4 1.4 2.0 2.1 2.6 3.1 2.9 4.1 1.8 3.4 2.5 1.9 1.6 5.0 4.0 2.4 5.0 2.1 0.2 0.3 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.0 3.2 0.0 0.2 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.2 0.1 0.8 0.4 0.0 0.0 0.3 0.5 0.1 1.1 1.8 0.0 0.0 0.0 0.1 0.9 0.4 0.8 0.3 0.6 2.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.3 0.2 0.0 30.8 0.4 0.2 28.1 0.4 0.2 1.5 0.4 23.4 0.1 2.3 0.7 25.3 0.4 12.4 0.3 1.2 10.9 2.6 2.2 2.5 2.4 2.3 2.7 3.7 3.5 3.6 3.1 3.4 5.0 1.0 3.2 17.0 0.0 0.2 0.5 5.8 18.9 4.6 0.1 10.6 5.3 1.7 14.3 23.3 22.0 2.1 1.5 0.3 0.4 3.9 5.9 4.6 13.6 2.0 2.1 1.2 0.0 0.5 3.8 0.3 7.7 3.1 25.6 2.5 4.6 0.7 0.7 18.1 0.0 1.0 0.6 6.1 29.5 3.1 5.7 9.3 22.4 3.6 23.4 14.4 1.4 0.0 1.5 0.1 2.4 0.1 8.6 0.1 3.0 0.5 0.1 11.0 0.2 0.0 4.2 4.1 5.4 5.5 15.9 1.6 0.8 1.7 4.1 1.5 6.3 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM4SF5 ENSG00000142484 "Transmembrane 4 L six family member 5" O14894 17 4771884-4783213 "Predicted membrane proteins, Transporters" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 174.7;liver: 204.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 115.2;Hepatocytes: 275.4;Intestinal goblet cells: 143.9;Paneth cells: 285.4;Proximal enterocytes: 618.4" "Cancer enriched" "Detected in many" 9 "liver cancer: 219.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 53.7;Hep G2: 96.0;OE19: 60.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA055674 Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA055674: " "unprognostic (1.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (4.44e-2)" "unprognostic (9.33e-2)" "unprognostic (3.57e-2)" "unprognostic (1.95e-1)" "unprognostic (5.21e-3)" 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 174.7 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 11.6 204.6 0.0 0.2 0.0 0.0 0.0 1.4 8.1 0.0 0.6 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 158.1 0.0 0.0 0.1 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 53.7 2.6 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 96.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.7 0.0 60.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.8 0.0 1.8 0.0 0.1 0.0 40.5 5.9 0.9 2.0 0.0 0.0 0.1 115.2 5.3 0.1 8.9 4.6 0.0 57.6 0.0 4.5 0.0 4.6 275.4 0.1 0.0 0.1 143.9 0.0 4.8 0.3 2.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.0 285.4 0.0 0.1 0.0 618.4 72.8 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.5 0.0 47.8 0.0 TMA7 "CCDC72, HSPC016" ENSG00000232112 "Translation machinery associated 7 homolog" Q9Y2S6 3 48440257-48444208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (1.26e-3)" "unprognostic (1.21e-1)" "unprognostic (9.10e-2)" "unprognostic (1.18e-2)" "unprognostic (2.06e-1)" "unprognostic (5.02e-2)" "unprognostic (3.55e-2)" "prognostic favorable (8.33e-4)" "unprognostic (1.14e-2)" "unprognostic (3.85e-3)" "unprognostic (1.92e-2)" "unprognostic (2.55e-2)" "unprognostic (1.14e-2)" "unprognostic (9.31e-3)" "unprognostic (3.13e-2)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" 252.5 276.8 498.7 220.7 507.8 434.6 241.9 504.6 588.9 236.5 500.2 253.3 192.8 179.4 344.5 310.5 181.7 117.9 355.4 502.2 514.7 317.6 273.2 208.0 279.3 511.7 510.0 259.6 230.3 309.8 302.0 146.6 505.9 239.6 229.3 295.4 215.9 142.7 511.6 215.1 220.4 132.7 513.0 272.9 235.5 216.0 511.9 388.3 232.4 287.4 297.7 213.3 239.3 514.5 565.0 398.8 634.2 456.6 514.0 497.1 435.6 454.1 355.7 425.1 419.3 326.3 395.9 365.2 315.3 397.8 553.6 215.5 559.8 512.5 471.6 452.6 475.5 689.4 910.3 845.8 399.0 792.2 443.0 459.7 538.2 402.6 388.8 414.2 546.0 641.1 376.6 379.0 615.3 581.2 929.4 1071.2 847.1 607.0 637.3 262.2 397.0 620.4 746.0 748.7 207.8 526.1 511.0 369.3 736.1 583.6 356.7 1156.3 412.1 358.0 650.8 560.5 902.6 626.1 1001.6 902.8 459.1 754.2 379.9 1923.2 1058.7 2195.0 1127.1 1022.5 1237.6 1412.6 1486.0 1377.1 1150.8 1172.2 1464.7 1408.1 2036.5 943.8 1028.9 1521.6 1652.1 2663.7 498.7 507.8 504.6 588.9 502.2 514.7 511.7 510.0 505.9 513.0 511.9 514.5 518.8 240.4 370.4 20.9 615.0 716.3 534.0 1308.9 618.6 219.6 866.8 1111.2 633.4 513.3 616.2 901.2 106.3 785.4 797.4 948.2 1717.8 566.9 653.6 524.8 511.4 474.5 635.3 609.1 25.8 1032.9 830.9 443.7 356.3 646.1 454.4 376.5 574.7 1098.6 854.5 119.5 25.4 985.5 695.8 652.4 790.5 1123.9 646.8 544.3 777.3 18.7 850.3 522.8 1080.3 10.1 28.3 872.9 980.3 464.6 593.9 584.6 1211.0 1438.8 466.4 321.9 355.0 393.6 448.4 547.4 689.4 805.5 898.4 440.1 757.1 351.9 937.2 572.2 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 988.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 32: Non-specific - Translation" "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: AB_2732691" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (4.18e-3)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.33e-1)" "unprognostic (9.91e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.08e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (3.65e-2)" 56.0 80.2 53.0 120.2 60.3 225.1 153.3 56.7 68.2 114.9 67.0 120.0 63.5 174.7 47.8 100.1 91.7 99.6 71.2 48.0 61.0 93.2 393.7 119.2 196.4 71.2 68.6 86.8 82.5 70.7 15.8 98.5 65.1 105.2 97.1 9.2 224.0 104.1 20.4 95.6 78.8 130.6 61.3 111.2 125.5 73.3 61.5 238.6 312.3 49.7 142.9 146.8 70.7 89.8 220.5 195.8 186.9 174.8 233.5 185.6 135.8 169.7 352.0 324.4 358.1 247.9 988.1 370.2 423.9 387.9 234.5 228.3 212.3 272.9 339.4 228.4 82.5 192.0 67.8 352.3 207.5 404.1 137.4 219.1 280.7 240.1 352.3 433.9 361.8 187.8 134.3 0.9 257.7 71.8 353.0 135.4 115.8 340.3 181.1 214.7 532.0 359.3 291.3 207.9 90.7 110.5 201.8 267.6 109.9 197.2 161.3 154.0 451.9 211.3 249.4 190.5 126.6 139.4 84.3 366.6 62.0 432.7 143.2 159.7 113.3 207.0 102.6 121.8 155.3 70.1 158.8 123.8 126.1 95.3 208.6 181.7 72.4 223.9 111.0 33.7 183.8 248.7 53.0 60.3 56.7 68.2 48.0 61.0 71.2 68.6 65.1 61.3 61.5 89.8 93.3 125.0 78.1 33.0 179.3 160.3 257.1 307.3 157.6 0.7 144.9 118.4 53.9 143.0 202.8 163.7 0.0 45.8 91.8 48.2 80.3 153.7 41.3 141.1 47.6 140.0 90.5 68.3 1.0 118.8 41.1 82.2 88.2 161.4 58.9 126.6 271.3 317.6 107.1 1.7 2.2 163.1 160.7 249.6 419.9 23.6 94.1 189.8 161.9 63.7 229.4 4.7 83.4 25.6 114.0 127.8 55.1 93.3 117.8 324.2 31.0 52.9 257.0 1.1 65.7 181.9 80.2 23.1 74.9 146.3 177.2 30.4 164.8 109.4 146.3 270.2 TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.1;Inhibitory neurons: 6.4;Oligodendrocyte precursor cells: 13.0;Proximal tubular cells: 11.5" "Cancer enriched" "Detected in some" 4 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "RPMI-8226: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 170000 "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: AB_2686286" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-5)" "unprognostic (3.37e-1)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-3)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-2)" "unprognostic (2.16e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.67e-2)" "unprognostic (1.51e-2)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 0.3 0.1 4.6 0.0 3.0 0.0 0.1 6.1 6.4 0.4 0.0 0.1 1.2 0.1 0.0 0.1 0.1 0.1 0.5 2.6 6.2 3.6 0.4 0.1 0.1 17.9 5.1 0.2 0.0 0.0 0.1 0.1 10.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.7 0.1 8.7 0.3 0.1 1.9 6.5 0.0 0.2 0.0 0.1 0.1 0.2 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 4.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 4.6 3.0 6.1 6.4 2.6 6.2 17.9 5.1 10.2 8.7 6.5 11.1 0.1 0.0 0.0 2.6 0.1 0.3 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 6.4 0.0 0.0 1.9 0.7 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 0.0 0.2 0.5 1.2 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TMEM169 FLJ34263 ENSG00000163449 "Transmembrane protein 169" Q96HH4 2 216081866-216102783 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;retina: 3.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.4;Cone photoreceptor cells: 22.9;Excitatory neurons: 13.1;Inhibitory neurons: 13.9;Oligodendrocyte precursor cells: 11.1;Oligodendrocytes: 9.3;Rod photoreceptor cells: 11.6" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.3;RPTEC TERT1: 12.3;SCLC-21H: 9.9;SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "HPA062462, HPA062797, HPA070657, HPA074877" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" Centrosome "HPA062462: AB_2732684, HPA062797: AB_2732690, HPA070657: AB_2686293, HPA074877: " "unprognostic (5.15e-2)" "unprognostic (2.93e-1)" "unprognostic (7.87e-3)" "unprognostic (4.69e-7)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.97e-1)" "unprognostic (4.43e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (2.79e-2)" "unprognostic (7.51e-3)" "unprognostic (4.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" 0.5 1.0 1.4 1.0 3.0 0.3 0.2 1.5 2.6 0.7 0.0 0.4 0.7 0.3 0.7 0.2 1.0 0.8 0.4 2.3 2.1 1.8 1.7 0.6 1.0 2.6 2.1 0.3 0.3 0.1 0.8 0.1 2.8 0.4 0.3 3.4 0.2 0.3 0.3 0.5 0.6 0.4 1.0 1.0 0.2 0.3 1.7 1.0 2.6 0.3 0.7 0.2 0.1 2.8 0.0 0.3 7.3 0.1 1.0 0.0 0.0 0.3 0.2 0.2 0.8 0.3 2.4 0.0 5.8 0.3 0.4 0.1 0.9 0.0 0.2 1.4 0.3 2.9 0.1 1.4 1.9 0.1 0.5 0.6 0.6 0.5 0.7 1.8 0.0 0.9 0.0 0.3 6.3 0.8 0.2 0.1 4.1 0.0 0.0 1.4 2.0 0.0 12.3 0.0 9.9 14.5 0.3 0.1 5.7 4.0 0.5 1.0 0.0 0.2 0.4 0.0 0.4 1.7 2.2 0.4 1.9 0.2 1.4 0.8 1.0 0.1 1.2 1.0 0.9 1.5 2.0 1.4 0.0 1.4 2.1 0.9 2.3 0.3 3.2 0.1 3.7 0.7 1.4 3.0 1.5 2.6 2.3 2.1 2.6 2.1 2.8 1.0 1.7 2.8 0.3 0.0 0.0 2.0 0.9 0.0 0.0 0.0 0.0 14.4 0.1 0.5 0.8 4.3 0.0 5.5 22.9 0.1 0.3 0.0 0.0 0.6 0.0 0.4 0.4 0.2 4.9 0.0 13.1 0.0 0.0 0.2 0.5 0.5 0.0 0.0 1.4 0.8 0.4 0.0 13.9 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 3.7 0.2 2.2 3.1 11.1 9.3 0.1 0.6 0.4 0.3 0.1 0.3 2.8 0.1 11.6 0.0 3.6 0.4 0.0 0.7 0.0 0.0 0.0 0.8 0.1 0.2 0.1 TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1656.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 1171.9;monocytes: 502.3;Paneth cells: 762.4;Proximal enterocytes: 922.5;Proximal tubular cells: 976.5" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 865.5;intermediate monocyte: 586.0" "Lineage enriched" "Detected in many" 5 "monocytes: 865.5" "Group enriched" "Detected in some" 17 "HSkMC: 642.7;THP-1: 215.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" 120.9 49.5 48.5 190.8 50.1 13.5 77.8 50.7 65.8 74.5 43.0 251.8 167.7 25.9 25.7 50.4 81.5 197.3 208.5 45.4 58.0 356.5 1656.5 95.6 177.5 69.2 60.1 143.1 53.6 7.3 22.7 115.0 64.5 48.9 244.9 34.1 42.5 28.3 11.0 34.7 286.6 99.0 65.0 87.0 94.5 11.1 52.2 26.1 33.6 36.1 93.7 158.6 92.4 73.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 25.7 0.4 0.8 0.0 0.1 0.6 0.1 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.6 0.8 0.2 642.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.1 0.9 0.5 0.1 0.0 0.1 1.0 11.8 0.1 0.0 1.9 1.4 0.6 0.3 0.2 0.2 0.0 215.7 0.0 0.0 3.2 0.5 0.2 0.4 0.2 0.6 0.0 0.3 0.0 5.3 865.5 50.5 2.3 586.0 3.4 2.5 0.6 0.7 164.3 0.6 0.7 0.4 8.6 0.6 309.3 7.7 0.6 498.5 48.5 50.1 50.7 65.8 45.4 58.0 69.2 60.1 64.5 65.0 52.2 73.2 22.2 3.2 9.3 14.4 16.9 12.6 0.5 0.9 5.7 156.9 52.2 74.0 73.7 190.1 14.4 375.2 2.1 0.9 2.8 419.4 166.3 95.1 18.5 6.1 14.5 19.8 128.1 13.5 0.1 34.0 1.0 243.7 14.8 2.1 54.4 61.9 22.9 1171.9 92.5 6.7 0.6 252.1 46.8 98.5 44.4 12.2 43.5 190.0 16.0 8.4 502.3 87.3 1.0 7.5 0.1 65.4 762.4 3.4 1.5 2.5 922.5 976.5 11.3 17.9 0.0 6.7 34.0 4.0 3.8 1.8 15.6 2.7 9.1 0.4 263.7 2.8 TMEM183A C1orf37 ENSG00000163444 "Transmembrane protein 183A" Q8IXX5 1 203007374-203024848 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072607 Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA072607: AB_2686539" "unprognostic (2.94e-3)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (3.41e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (6.46e-2)" "unprognostic (3.21e-2)" "unprognostic (4.82e-3)" "unprognostic (5.28e-2)" "unprognostic (7.84e-2)" "unprognostic (4.83e-2)" "unprognostic (6.01e-3)" "unprognostic (9.55e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" 21.6 19.1 27.6 17.0 28.8 76.6 22.1 28.2 35.1 22.9 23.8 30.9 26.6 19.8 18.8 30.3 19.4 14.1 17.0 30.1 30.1 22.8 23.9 21.0 21.7 26.7 25.8 20.1 28.7 17.8 12.2 14.4 27.7 21.2 30.2 21.8 25.4 16.4 14.8 27.5 26.1 19.9 23.7 22.2 25.2 34.1 26.7 30.0 22.2 12.7 24.1 23.4 22.9 27.0 32.7 31.2 39.2 64.6 50.6 37.7 64.4 32.2 31.7 36.4 31.7 38.1 33.6 81.1 22.6 41.7 14.6 40.4 53.1 45.1 30.1 26.6 64.5 40.2 33.8 42.3 36.6 72.6 33.9 37.3 49.3 30.1 60.2 36.8 46.6 64.4 83.8 28.7 34.5 73.3 59.7 74.4 107.7 44.0 49.2 45.4 66.7 65.7 57.0 31.6 50.2 62.7 48.0 79.0 48.1 61.9 56.6 56.6 34.8 24.4 34.2 42.3 35.7 28.8 49.7 62.4 27.0 55.7 26.3 33.3 33.6 51.2 23.5 29.2 23.1 23.8 26.3 26.6 37.4 26.2 29.8 24.7 28.7 36.6 27.8 26.8 30.6 37.4 27.6 28.8 28.2 35.1 30.1 30.1 26.7 25.8 27.7 23.7 26.7 27.0 39.7 16.0 20.5 3.6 40.4 73.4 61.5 62.2 41.5 22.8 62.2 48.6 14.9 54.3 52.1 35.0 10.4 53.2 57.3 70.4 70.5 88.6 161.1 31.1 34.9 36.2 52.7 103.7 13.2 76.1 86.0 34.8 42.3 34.4 17.7 34.6 40.7 53.6 60.4 18.5 11.8 87.5 63.1 63.1 52.0 113.7 27.1 49.7 39.2 6.5 71.1 26.6 50.4 3.5 7.2 52.7 57.6 29.3 62.1 100.2 102.3 100.4 44.5 28.0 19.7 38.3 46.7 95.0 80.9 72.9 82.1 51.6 48.3 39.6 88.6 105.2 TMEM184B "C22orf5, DKFZP586A1024, FM08, HS5O6A" ENSG00000198792 "Transmembrane protein 184B" Q9Y519 22 38219291-38273010 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 86.8;Oligodendrocytes: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024076 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus, Cytosol" Nucleoplasm "HPA024076: AB_1858106" "unprognostic (1.52e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-1)" "unprognostic (8.96e-2)" "unprognostic (3.82e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.94e-6)" "unprognostic (1.14e-2)" "unprognostic (5.18e-2)" "unprognostic (4.52e-2)" "unprognostic (9.20e-2)" "unprognostic (1.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (2.96e-1)" 28.6 21.9 49.5 14.0 52.3 5.8 24.9 54.5 59.6 18.6 22.1 21.0 16.9 19.4 7.2 17.3 17.1 14.5 35.7 49.6 48.2 25.9 11.4 35.9 8.4 56.8 56.0 16.2 18.4 18.9 34.3 38.4 54.8 18.8 10.8 15.2 22.6 14.4 28.7 16.0 17.6 14.0 52.9 22.0 22.4 7.5 56.7 6.2 26.1 17.4 8.2 18.4 16.5 66.9 55.8 47.5 27.5 21.9 53.6 42.6 63.4 58.8 82.9 46.9 41.5 35.1 25.2 10.6 44.9 87.6 42.4 67.2 24.9 57.8 31.6 37.9 45.0 20.9 34.0 29.5 56.3 16.6 28.0 36.1 50.2 55.4 61.5 48.5 59.5 15.9 13.5 36.2 41.5 31.6 10.6 14.1 22.4 41.2 43.4 18.1 24.8 10.6 34.8 60.6 59.3 10.5 44.2 63.6 32.0 31.7 35.2 12.0 89.2 47.7 48.4 42.5 36.2 74.5 197.9 8.5 69.2 12.1 42.0 14.2 3.3 4.7 5.3 2.3 4.6 1.4 2.9 4.0 4.5 1.1 2.1 2.5 10.9 6.2 1.6 7.0 1.0 3.2 49.5 52.3 54.5 59.6 49.6 48.2 56.8 56.0 54.8 52.9 56.7 66.9 43.4 6.4 14.8 86.8 7.5 12.4 19.8 22.3 17.6 16.4 15.9 10.5 17.1 8.6 18.7 14.7 2.1 35.0 17.8 12.5 3.9 17.3 5.6 17.4 15.5 34.6 25.9 4.6 42.6 22.2 48.3 17.4 13.3 33.8 2.5 15.3 18.2 4.4 14.7 15.2 40.7 19.7 12.2 8.5 19.7 2.4 11.8 8.4 14.2 22.5 12.2 44.4 23.7 42.3 93.1 28.3 9.8 13.5 35.6 32.9 11.1 4.3 15.9 9.0 19.7 15.3 27.0 3.3 6.1 5.3 9.7 78.4 9.3 10.2 10.1 37.0 TMEM192 FLJ38482 ENSG00000170088 "Transmembrane protein 192" Q8IY95 4 165070608-165208549 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014717, HPA024110" Enhanced Supported Nucleoplasm,Endosomes,Lysosomes NA NA "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" Nucleoplasm "HPA014717: AB_1844373, HPA024110: AB_2204898" "prognostic unfavorable (9.52e-4)" "unprognostic (5.38e-3)" "unprognostic (9.16e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.55e-2)" "unprognostic (2.91e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (3.10e-1)" "unprognostic (3.27e-2)" "unprognostic (5.06e-2)" "prognostic favorable (2.33e-14)" "unprognostic (2.09e-2)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (9.30e-2)" 12.0 15.2 4.9 7.2 5.9 6.6 13.2 7.5 7.0 9.9 7.1 11.5 9.7 10.5 9.0 8.8 11.2 10.3 12.6 4.8 5.2 48.3 45.2 10.6 8.9 4.7 5.5 24.5 22.3 24.6 5.1 10.8 5.0 22.1 13.3 10.7 14.5 8.4 15.0 5.4 9.3 8.6 4.6 9.1 10.5 9.8 4.8 6.6 26.8 17.0 7.7 8.5 5.4 6.2 13.5 19.9 7.1 18.0 18.1 6.4 16.5 20.1 29.4 20.5 22.8 11.7 21.6 29.5 11.7 13.0 33.4 11.8 26.8 20.6 23.6 19.2 13.8 16.4 14.1 13.4 46.1 41.0 21.2 23.3 42.8 18.4 37.4 17.8 17.0 15.6 28.4 48.1 25.4 29.4 7.1 12.0 14.8 28.1 16.9 16.0 6.2 27.1 16.4 19.6 15.2 15.9 31.4 49.1 31.9 10.4 23.9 18.5 12.6 9.0 11.1 28.6 23.0 46.9 67.0 40.8 21.6 22.2 36.6 2.9 16.6 4.8 12.1 14.9 16.3 26.7 9.4 12.6 15.7 20.2 10.4 12.6 1.7 18.7 8.3 16.3 8.5 10.7 4.9 5.9 7.5 7.0 4.8 5.2 4.7 5.5 5.0 4.6 4.8 6.2 12.3 32.1 36.2 18.9 24.0 9.7 18.4 10.5 10.2 33.0 21.5 15.7 35.0 42.9 19.1 55.2 16.7 31.4 15.4 17.0 11.7 21.0 26.4 11.2 17.0 19.0 21.7 10.1 16.4 25.8 20.5 18.9 7.7 15.5 40.4 26.1 27.8 77.7 38.2 37.0 16.5 18.2 6.1 27.4 17.7 11.1 39.7 22.3 28.4 11.2 21.3 35.8 28.8 14.6 20.9 11.5 14.3 33.4 11.8 33.7 26.3 63.4 10.9 27.1 6.6 30.7 20.7 17.8 18.3 12.0 12.9 33.7 15.9 27.1 24.0 14.2 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM209 "FLJ14803, NET31" ENSG00000146842 "Transmembrane protein 209" Q96SK2 7 130164713-130207770 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031678 Uncertain Approved "Nuclear membrane,Nuclear speckles,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Nuclear speckles, Vesicles" "HPA031678: AB_10603135" "unprognostic (3.03e-1)" "unprognostic (5.06e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (4.50e-3)" "unprognostic (5.98e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (3.19e-1)" "unprognostic (6.00e-2)" "unprognostic (2.34e-3)" "unprognostic (1.11e-1)" "unprognostic (3.48e-1)" "unprognostic (1.68e-2)" "unprognostic (3.24e-1)" 8.9 15.3 4.1 8.4 6.2 9.6 10.6 7.2 6.5 7.4 13.0 11.0 8.8 10.8 9.5 5.5 9.6 6.4 6.2 4.0 5.2 8.6 10.4 9.2 11.9 6.1 6.1 10.2 8.5 15.1 4.4 9.5 6.4 8.3 11.2 13.3 7.9 8.4 5.2 7.2 10.7 9.0 5.9 10.5 7.6 15.0 5.4 14.2 16.2 7.7 12.1 7.6 4.3 9.6 23.4 21.8 29.3 36.7 16.8 17.2 21.4 20.8 20.9 18.3 24.7 23.0 39.2 34.6 15.1 13.3 34.5 34.2 34.7 24.2 33.0 42.7 20.0 17.9 34.0 16.5 29.6 38.2 17.2 18.9 24.6 37.0 36.8 11.4 14.5 35.1 58.9 38.2 23.2 30.2 73.2 23.6 44.1 20.9 19.4 38.9 33.1 57.4 19.1 29.3 26.2 40.0 47.5 75.8 31.3 22.7 23.7 25.6 11.4 33.0 13.1 35.4 50.6 51.7 81.6 70.4 54.7 43.4 53.0 16.1 12.2 13.8 22.0 18.3 23.0 18.3 22.3 20.2 12.0 17.3 25.6 22.3 1.8 19.5 16.8 14.9 24.6 15.1 4.1 6.2 7.2 6.5 4.0 5.2 6.1 6.1 6.4 5.9 5.4 9.6 12.3 3.2 12.3 11.4 15.3 4.7 4.0 8.2 6.8 13.6 8.8 5.2 8.6 10.0 9.8 9.2 4.2 8.9 15.2 7.2 1.9 6.4 33.5 9.6 8.0 9.5 13.8 25.9 10.4 9.1 9.3 7.5 7.7 10.4 10.1 10.0 9.7 9.4 7.9 5.0 13.0 11.9 8.2 13.1 4.4 8.5 6.5 7.8 7.2 15.0 7.7 18.1 8.2 10.6 20.9 7.6 11.6 5.3 11.0 5.3 13.4 4.9 9.8 14.6 0.0 9.0 5.9 16.6 16.0 6.4 5.4 6.6 13.1 12.1 9.5 3.7 TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: AB_10602481" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (4.12e-3)" "unprognostic (1.90e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.96e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.39e-10)" "unprognostic (1.54e-2)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (2.92e-2)" 45.8 39.0 14.7 30.8 15.8 23.1 43.2 15.3 17.3 45.0 28.7 38.3 30.5 43.7 66.2 31.5 37.5 30.7 36.7 14.8 17.0 30.0 46.5 37.7 25.1 19.1 18.7 41.4 79.9 56.0 60.4 45.8 18.3 37.9 41.7 8.8 83.6 44.4 35.7 37.8 33.6 45.1 15.6 37.4 40.8 19.5 17.8 21.7 42.3 21.3 34.4 36.7 33.9 14.9 82.4 53.5 32.2 68.2 102.8 103.7 69.4 105.9 142.4 76.0 85.2 53.0 67.3 37.6 52.4 156.6 59.7 57.6 39.3 74.9 61.0 36.3 44.1 49.9 41.4 109.8 128.1 45.7 82.5 90.4 52.7 66.8 112.0 58.6 83.5 24.3 46.0 75.3 85.9 59.6 23.3 34.1 23.1 110.0 42.8 31.3 58.5 91.0 57.1 57.0 27.8 32.3 49.4 83.3 38.2 31.0 45.9 27.0 72.4 55.2 52.8 57.0 60.4 100.9 73.3 59.2 71.1 56.8 77.9 5.7 3.5 2.8 3.9 3.8 5.0 2.5 3.0 2.8 2.8 2.8 1.5 2.1 0.6 5.6 2.2 5.0 2.6 2.5 14.7 15.8 15.3 17.3 14.8 17.0 19.1 18.7 18.3 15.6 17.8 14.9 15.8 3.2 20.1 3.9 18.5 7.6 9.6 10.4 3.4 9.3 19.8 11.0 8.2 21.5 15.0 14.7 10.4 43.6 15.0 37.5 1.9 24.7 6.4 11.3 25.4 17.5 17.9 18.5 4.8 34.6 62.9 26.9 33.1 23.8 14.5 17.0 32.5 28.9 27.3 6.7 4.4 37.6 10.2 18.9 12.8 7.8 32.6 11.7 5.4 6.5 14.6 6.9 14.4 4.0 3.8 21.7 22.3 20.3 63.0 20.8 25.4 10.4 11.0 8.4 26.3 11.6 19.6 24.4 12.7 8.4 9.2 71.7 12.0 17.6 27.6 15.8 TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.9;retina: 18.3;testis: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 572.0;Early spermatids: 129.9;Late spermatids: 302.1" "Cancer enriched" "Detected in single" 14 "thyroid cancer: 4.9" "Region enriched" "Detected in many" 4 "thalamus: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA052804, HPA063207" Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA052804: AB_2681957, HPA063207: AB_2732697" "unprognostic (1.31e-2)" "unprognostic (4.57e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (5.85e-2)" "unprognostic (4.38e-3)" "unprognostic (2.17e-3)" "unprognostic (2.82e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.32e-2)" 0.0 0.0 1.2 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.2 1.6 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.9 6.9 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.5 0.7 1.5 0.2 1.6 0.3 0.3 6.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 572.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 129.9 0.0 1.2 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 302.1 2.8 0.1 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.1 3.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM222 "C1orf160, DKFZP564D0478" ENSG00000186501 "Transmembrane protein 222" Q9H0R3 1 27322145-27336400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016579, HPA059374" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Cell Junctions" "HPA016579: AB_2669392, HPA059374: AB_2683995" "unprognostic (3.65e-1)" "unprognostic (5.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-3)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (4.11e-2)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "unprognostic (1.96e-2)" "unprognostic (2.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-3)" "unprognostic (5.28e-2)" "unprognostic (1.56e-1)" "unprognostic (3.83e-2)" "unprognostic (7.80e-2)" 26.6 38.2 61.9 13.0 60.1 23.8 27.1 58.7 76.8 25.1 57.4 26.9 15.0 28.1 24.4 36.1 29.6 19.2 34.5 61.2 65.4 32.8 49.4 22.4 16.1 61.7 64.4 26.6 28.6 30.6 38.4 13.0 62.3 39.0 14.4 10.6 26.7 23.9 36.8 28.9 23.8 18.8 60.7 25.0 30.1 28.8 63.8 21.1 29.4 20.7 14.1 27.6 24.2 59.5 26.2 31.2 25.7 42.3 39.2 28.2 20.7 39.6 45.1 52.9 44.8 13.0 53.5 16.5 30.2 42.4 24.6 35.3 28.3 38.5 21.9 22.0 54.4 27.6 24.7 30.1 58.0 27.8 26.5 49.4 21.5 50.8 28.7 24.3 35.7 32.4 21.2 37.1 33.6 23.4 40.1 29.2 48.3 27.0 38.6 32.8 17.7 33.5 51.6 15.2 54.8 48.4 30.6 42.6 39.7 9.2 42.3 44.2 33.1 31.1 26.1 50.6 38.1 39.8 38.5 17.6 47.1 53.3 45.8 38.2 20.6 27.7 32.5 32.5 24.8 37.4 29.7 24.6 18.5 30.0 29.1 30.2 56.3 31.9 35.3 30.4 37.4 25.6 61.9 60.1 58.7 76.8 61.2 65.4 61.7 64.4 62.3 60.7 63.8 59.5 22.9 9.6 13.5 8.5 25.4 11.7 13.3 26.2 15.9 42.1 24.0 29.2 8.9 18.6 13.3 12.9 14.6 30.9 20.9 24.5 39.2 39.1 25.5 13.2 17.2 20.6 29.9 43.8 12.4 40.5 33.9 22.6 18.8 12.4 17.1 22.0 11.0 15.1 28.3 43.7 15.0 21.0 40.7 8.5 12.9 76.9 20.2 12.2 26.6 6.5 20.6 51.9 22.6 17.1 14.4 48.6 22.7 19.9 18.6 19.9 28.8 19.2 7.9 18.7 13.1 19.6 20.3 27.2 18.0 19.3 13.5 30.8 20.5 22.4 23.1 12.4 TMEM223 MGC3196 ENSG00000168569 "Transmembrane protein 223" A0PJW6 11 62771629-62792006 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014504 Approved Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA014504: AB_1853881" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.87e-1)" "unprognostic (3.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-2)" "unprognostic (3.20e-3)" "unprognostic (1.97e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-3)" "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (7.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.14e-3)" "unprognostic (9.75e-2)" 13.1 20.9 10.4 9.4 12.0 6.4 12.8 12.4 13.4 13.2 11.6 15.7 11.0 12.9 9.7 13.3 11.7 5.5 27.9 10.4 10.5 17.3 22.5 11.1 12.0 11.6 10.2 11.4 19.8 8.0 13.2 7.1 11.8 14.8 7.4 5.2 15.3 7.2 16.1 13.3 14.4 5.3 10.0 16.6 15.4 6.7 10.4 7.3 13.8 8.5 7.0 12.2 11.1 12.1 29.2 24.4 14.3 19.6 11.8 13.5 19.5 15.3 13.4 16.9 14.1 21.5 34.9 21.6 36.8 11.1 22.5 43.3 17.3 18.9 9.6 34.7 32.5 16.1 26.9 25.9 20.6 20.0 18.4 14.4 18.8 11.2 13.9 20.3 13.9 28.2 24.8 15.8 12.6 42.3 20.3 44.3 28.2 30.2 29.2 24.7 17.3 48.8 26.8 18.3 24.3 32.0 16.0 32.3 43.0 14.5 48.1 18.4 13.9 20.2 24.4 18.7 18.5 32.1 27.5 25.1 24.0 17.8 21.5 21.0 41.3 25.0 71.3 46.2 68.8 77.6 69.8 69.9 46.8 81.8 74.9 73.0 19.0 66.2 29.8 75.6 66.8 41.5 10.4 12.0 12.4 13.4 10.4 10.5 11.6 10.2 11.8 10.0 10.4 12.1 31.9 12.8 5.6 4.2 24.1 13.5 15.3 39.7 8.6 17.9 27.6 45.0 18.8 52.9 25.2 20.2 12.5 49.4 22.8 30.2 62.6 37.2 2.6 29.1 26.9 28.9 20.5 18.5 6.1 44.3 42.9 22.0 15.3 22.3 19.7 22.4 31.8 36.0 37.6 6.7 8.0 32.6 38.7 20.1 13.6 3.4 32.6 16.2 19.6 4.7 16.2 16.5 35.0 6.0 5.7 36.1 19.3 26.4 25.4 22.4 32.1 52.3 39.6 18.0 19.7 22.3 17.9 6.9 19.7 21.3 13.9 14.2 24.3 34.2 43.4 17.1 TMEM260 "C14orf101, FLJ20392" ENSG00000070269 "Transmembrane protein 260" Q9NX78 14 56488354-56650606 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 39.8" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 66.7;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003502 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA003502: AB_1078314" "unprognostic (4.63e-2)" "unprognostic (2.41e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.51e-1)" "unprognostic (3.58e-2)" "unprognostic (2.04e-1)" "prognostic favorable (7.11e-4)" "unprognostic (7.14e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-3)" "unprognostic (3.22e-1)" "unprognostic (2.23e-3)" "unprognostic (5.81e-2)" "unprognostic (8.11e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-2)" 4.6 4.3 4.5 4.0 5.4 2.1 5.5 4.7 4.9 39.8 12.4 5.8 5.2 6.2 7.8 3.4 7.4 5.9 2.5 4.4 4.5 6.8 5.6 4.4 4.7 4.6 4.4 9.3 4.5 7.3 3.7 5.7 4.5 5.2 5.8 6.9 3.8 4.5 2.2 5.6 5.7 3.9 4.4 4.0 5.5 5.2 4.5 5.8 8.4 2.2 3.8 4.7 3.6 7.3 8.0 5.5 4.2 8.9 14.5 11.9 8.2 8.4 9.2 5.4 6.4 2.6 5.8 6.5 8.0 6.2 6.1 9.1 9.7 6.1 8.4 8.1 4.9 4.2 2.7 3.6 10.2 5.9 9.6 14.6 10.7 3.0 10.3 9.8 7.1 4.9 5.2 6.8 7.1 5.3 3.1 2.2 3.9 13.0 8.6 4.3 6.7 2.2 9.0 11.7 8.8 4.3 9.4 6.7 5.5 7.8 8.6 9.0 10.0 10.9 4.1 8.2 4.2 4.1 3.5 3.8 6.8 4.3 5.5 0.0 1.1 1.2 1.3 0.8 0.9 0.7 0.8 0.7 0.9 0.7 1.2 0.8 0.5 2.5 0.7 1.9 1.3 0.8 4.5 5.4 4.7 4.9 4.4 4.5 4.6 4.4 4.5 4.4 4.5 7.3 12.2 19.2 17.2 39.8 13.0 5.4 7.1 5.9 5.7 14.6 8.0 7.7 3.7 2.8 8.5 22.0 4.2 10.2 9.8 9.4 1.9 8.1 88.5 22.8 17.6 8.3 18.0 7.6 66.7 3.8 7.7 10.4 9.2 29.1 12.0 20.0 8.9 13.3 6.5 6.7 62.8 10.0 6.1 12.8 5.0 31.5 15.2 8.7 1.8 39.4 11.1 5.2 14.4 69.9 106.0 5.6 7.6 10.9 9.3 9.3 9.5 4.8 14.2 16.4 0.0 7.0 8.0 9.3 11.0 10.0 5.5 11.1 8.9 14.5 12.1 8.0 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.1;liver: 100.0;parathyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.9;Hepatocytes: 184.5;Muller glia cells: 146.8;Proximal enterocytes: 575.7;Proximal tubular cells: 188.1" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "EFO-21: 26.9;Hep G2: 74.7;RPTEC TERT1: 60.0" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" 53.1 11.1 2.1 6.6 2.0 0.7 25.6 1.8 3.6 21.9 2.5 37.3 53.5 6.4 4.8 6.8 3.4 23.2 4.8 1.5 1.8 101.1 100.0 15.4 10.2 2.5 2.1 12.7 13.3 124.7 1.0 14.9 2.3 3.9 19.0 23.6 7.0 7.6 2.4 10.5 76.1 4.8 2.5 25.7 18.1 5.1 3.7 3.0 31.1 4.2 4.9 7.0 5.6 3.2 0.0 7.3 0.7 0.3 4.3 0.4 1.0 0.2 0.1 0.0 0.1 11.4 6.4 0.0 26.9 3.4 0.6 1.7 3.0 0.0 0.0 0.0 2.9 1.0 4.0 74.7 5.9 0.0 0.1 9.7 0.0 0.0 0.0 0.2 5.9 0.0 0.2 10.9 0.0 0.7 0.0 0.8 5.4 0.1 0.2 0.0 0.1 9.9 60.0 4.9 0.9 0.4 0.3 2.9 0.0 5.0 1.2 1.7 3.8 0.0 10.4 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.1 2.0 1.8 3.6 1.5 1.8 2.5 2.1 2.3 2.5 3.7 3.2 12.2 25.6 9.6 0.0 3.2 2.0 0.3 11.1 0.0 2.4 1.8 1.5 2.1 82.9 13.6 18.4 0.0 64.9 0.1 179.9 50.9 36.1 0.3 7.7 98.8 15.1 9.1 5.3 0.0 52.3 3.8 17.9 11.7 10.3 1.3 16.4 61.8 184.5 64.6 6.7 0.0 22.0 14.2 65.5 5.0 1.9 49.7 19.5 1.8 0.0 0.6 146.8 0.0 0.0 0.6 15.3 68.1 3.8 0.0 0.1 575.7 188.1 7.6 17.4 0.0 0.9 14.8 0.0 0.8 1.0 2.8 104.1 2.4 45.3 23.3 2.3 TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 200.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" 9.0 27.2 9.6 5.4 9.3 11.0 10.2 9.7 11.0 10.0 8.9 7.9 26.4 8.7 11.2 23.6 9.2 7.6 9.9 9.0 9.4 14.7 20.5 10.6 7.4 9.4 11.6 14.1 9.7 8.7 5.7 8.4 9.2 10.2 8.9 7.5 12.0 8.3 9.8 19.9 24.1 7.4 9.8 12.5 10.3 9.3 12.1 7.8 7.0 16.4 12.6 10.8 14.6 10.9 43.6 15.4 10.1 12.5 15.6 16.8 29.6 16.3 14.3 20.2 14.6 40.5 16.7 13.4 30.5 15.3 28.5 29.4 28.1 17.5 20.4 22.6 25.8 23.3 8.6 41.2 17.5 25.3 12.5 15.7 25.6 18.3 20.9 12.7 15.6 16.8 42.1 32.4 13.0 16.8 15.6 14.5 16.8 34.1 24.1 15.5 15.6 24.6 17.4 31.4 10.1 13.1 14.1 35.8 25.7 14.4 42.8 19.6 11.4 11.9 15.0 25.2 34.5 47.2 78.0 26.5 18.2 15.1 14.6 14.0 8.2 7.2 16.3 9.4 21.0 17.5 16.7 18.1 9.3 15.6 18.2 19.8 2.8 12.2 12.2 21.7 15.3 9.2 9.6 9.3 9.7 11.0 9.0 9.4 9.4 11.6 9.2 9.8 12.1 10.9 12.1 9.6 30.5 7.2 16.7 53.0 42.8 29.5 50.7 22.4 38.2 20.6 12.6 24.3 24.9 20.2 18.8 27.5 18.3 23.3 7.9 33.4 0.7 17.7 14.5 19.8 18.6 16.4 8.1 56.0 23.5 18.0 36.2 38.0 8.8 50.2 17.2 40.9 19.6 16.8 9.8 28.3 16.2 14.2 17.3 2.8 14.3 12.5 8.8 2.8 65.9 11.4 11.3 20.1 7.6 50.3 17.0 13.5 20.9 64.2 200.8 23.2 9.6 28.6 19.7 16.8 16.5 22.1 14.3 113.0 84.7 46.0 18.5 82.6 45.6 93.4 TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" 47.2 63.0 43.9 44.5 47.8 41.8 55.5 45.3 55.8 47.0 43.7 58.5 49.6 35.7 53.0 36.5 38.4 45.7 44.2 45.0 44.4 55.0 33.4 58.1 52.2 46.5 44.4 26.2 32.6 49.5 14.6 57.7 46.4 54.4 65.7 45.4 81.5 52.7 16.9 41.1 55.4 46.0 47.2 46.9 49.5 16.1 45.5 47.1 47.0 26.5 47.3 55.1 29.8 50.4 43.3 44.6 74.3 42.3 132.9 119.8 28.1 89.0 123.6 143.4 159.5 36.5 110.9 50.2 47.9 274.6 55.7 62.6 56.3 61.9 161.2 126.1 81.4 104.7 47.5 55.2 96.5 82.4 80.3 128.0 91.4 106.1 60.5 69.7 107.0 50.8 73.1 79.5 140.9 30.6 53.2 90.2 90.6 73.7 37.1 45.7 85.3 88.9 148.8 30.9 64.5 42.3 89.0 64.2 72.2 69.3 32.7 52.0 171.0 86.5 36.6 144.9 36.8 52.3 61.5 45.0 117.1 117.2 50.3 275.5 76.9 109.8 87.9 94.7 91.9 49.6 77.2 91.1 55.9 40.9 55.1 76.6 159.2 80.5 117.3 51.9 95.4 106.3 43.9 47.8 45.3 55.8 45.0 44.4 46.5 44.4 46.4 47.2 45.5 50.4 244.8 144.2 84.2 21.2 107.9 253.4 184.5 392.3 146.8 43.9 162.0 164.8 105.6 102.9 212.7 169.2 27.1 108.9 191.0 175.6 50.9 300.3 25.4 136.4 119.3 203.3 83.0 93.6 31.6 215.6 312.5 198.1 91.3 180.8 126.6 58.2 152.0 68.3 227.1 25.2 27.3 170.7 309.3 162.4 245.1 12.7 151.9 223.8 199.3 16.9 253.8 102.0 154.5 28.1 48.8 315.3 164.8 98.9 168.2 340.6 120.0 113.1 205.1 41.7 210.4 71.6 200.6 94.7 47.0 166.8 317.7 181.6 180.9 116.9 106.9 274.3 TMEM62 FLJ23375 ENSG00000137842 "Transmembrane protein 62" Q0P6H9 15 43123279-43185144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 61.0;U-266/84: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044461, HPA062359" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies, Cytoplasmic bodies" "HPA044461: AB_2678950, HPA062359: AB_2684747" "unprognostic (7.43e-2)" "unprognostic (4.96e-2)" "unprognostic (4.56e-2)" "prognostic favorable (9.72e-7)" "unprognostic (2.53e-1)" "unprognostic (1.98e-1)" "unprognostic (2.39e-2)" "unprognostic (1.41e-2)" "unprognostic (4.83e-2)" "unprognostic (3.30e-1)" "unprognostic (3.90e-2)" "unprognostic (1.77e-1)" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (6.48e-2)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" 7.1 4.6 4.8 6.0 5.0 9.0 22.9 8.2 6.7 8.1 3.6 13.1 13.1 5.4 12.3 6.2 7.5 7.9 5.1 5.3 4.8 7.6 10.3 8.8 7.2 4.5 4.5 3.2 8.1 13.7 4.6 10.3 5.0 6.1 14.4 8.9 13.6 7.1 9.4 5.2 11.7 6.5 5.0 6.1 10.2 2.0 5.4 4.0 8.5 6.6 8.0 7.6 5.4 5.6 14.9 7.9 3.5 6.8 4.3 5.5 36.4 13.9 17.6 24.1 33.3 12.5 28.5 15.0 7.9 13.2 21.7 27.6 14.8 10.9 8.7 17.7 6.8 12.2 15.4 9.5 9.4 12.7 10.5 3.9 13.0 10.6 7.4 6.8 13.6 3.7 10.9 12.7 2.8 3.5 0.0 3.0 1.2 61.0 3.2 7.5 3.7 7.9 12.9 18.6 22.2 9.6 10.9 27.2 6.7 3.9 14.6 12.9 8.0 11.9 4.9 8.5 22.7 10.6 67.1 10.7 11.0 14.0 10.4 0.5 0.7 1.1 0.8 0.3 1.0 0.7 1.1 1.0 0.7 0.8 0.7 0.9 0.2 1.6 0.4 1.7 2.0 0.4 4.8 5.0 8.2 6.7 5.3 4.8 4.5 4.5 5.0 5.0 5.4 5.6 7.7 16.0 4.6 12.1 18.8 2.3 4.1 2.8 5.7 5.6 12.3 6.3 2.6 8.6 5.0 12.9 10.4 21.9 7.0 12.5 5.9 12.9 1.6 9.6 3.7 5.6 4.2 9.1 36.3 14.8 25.2 4.8 11.2 13.9 5.1 7.0 6.1 7.3 7.5 1.7 33.4 11.4 6.1 6.5 4.8 3.7 2.5 7.1 5.4 18.7 6.4 7.8 6.2 29.1 34.5 12.2 8.1 1.2 16.5 2.7 12.8 3.4 6.1 9.9 6.6 4.1 5.2 2.2 1.0 8.6 2.8 34.1 7.4 3.8 11.0 4.8 TMEM9 TMEM9A ENSG00000116857 "Transmembrane protein 9" Q9P0T7 1 201134772-201171574 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008483 Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA008483: " "unprognostic (1.88e-1)" "prognostic unfavorable (6.57e-4)" "unprognostic (2.95e-1)" "unprognostic (3.67e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (2.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.88e-2)" "unprognostic (2.38e-1)" "unprognostic (9.17e-2)" "unprognostic (3.32e-1)" "unprognostic (9.90e-2)" 34.1 102.3 103.1 20.8 104.4 27.8 45.0 93.5 126.6 76.8 122.7 45.0 25.4 70.9 65.4 31.1 75.4 39.5 51.3 107.8 113.2 73.8 73.8 44.5 23.5 99.4 111.5 81.4 73.9 92.2 63.4 28.5 102.8 60.3 25.4 43.9 60.7 45.9 44.9 35.5 30.4 37.5 100.2 31.2 49.8 67.0 112.5 26.3 68.5 24.9 17.7 45.7 51.8 100.2 63.1 117.0 72.6 168.9 38.5 54.5 128.5 48.6 51.5 76.0 68.2 115.7 99.8 33.2 69.2 73.4 70.1 123.3 76.5 80.1 37.3 21.3 131.9 58.1 182.4 76.6 73.8 28.2 51.9 65.0 87.0 71.2 43.0 91.3 47.7 46.2 105.6 35.5 66.2 81.0 34.1 46.1 111.0 57.3 285.3 60.7 108.4 44.0 87.9 48.0 67.6 137.7 86.7 146.9 91.8 107.4 180.3 48.5 35.7 84.8 70.0 68.5 59.8 143.9 135.2 26.1 64.4 30.1 42.0 49.8 59.8 33.7 45.7 41.8 52.2 54.5 44.0 37.8 51.5 49.2 64.6 42.7 41.0 32.9 38.5 56.1 43.0 75.5 103.1 104.4 93.5 126.6 107.8 113.2 99.4 111.5 102.8 100.2 112.5 100.2 20.9 51.3 49.5 17.0 13.4 12.9 31.4 65.6 27.3 61.0 56.2 65.7 39.3 40.0 48.0 36.8 31.3 44.4 9.3 7.9 17.6 88.8 58.0 37.3 58.6 26.3 31.8 43.6 15.7 74.7 52.1 59.9 20.9 46.4 13.3 46.3 30.0 40.4 28.1 8.4 22.1 26.9 36.7 13.4 11.9 60.9 70.8 15.6 23.2 8.4 11.8 102.3 25.7 15.6 10.1 40.3 18.8 53.0 18.8 28.5 8.3 56.9 54.5 32.8 13.1 33.3 42.1 54.8 76.7 14.5 13.9 13.0 13.0 130.7 28.4 27.8 TMSB4X "TB4X, TMSB4" ENSG00000205542 "Thymosin beta 4 X-linked" P62328 X 12975110-12977227 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 30742.3;Langerhans cells: 57681.0;monocytes: 48133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033806 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Vesicles, Cytosol" "CAB033806: AB_2256019" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.72e-2)" "unprognostic (3.27e-2)" "unprognostic (7.98e-3)" "unprognostic (1.71e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.20e-4)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" 6173.6 4217.0 3255.7 5088.7 3773.0 8722.4 4452.0 3539.2 4521.9 3685.7 2999.1 4327.1 1776.8 3731.3 2877.9 2069.6 2709.3 4129.3 2652.4 3319.4 3573.5 3300.1 2360.4 6225.5 10448.1 4064.7 3620.0 2592.1 1852.6 483.2 1053.7 2450.2 4203.0 2335.6 3793.9 273.3 1886.8 2441.9 816.5 1962.4 3671.2 3340.7 4219.2 7935.5 4690.0 486.8 3591.8 6377.6 1648.7 1475.0 7233.8 5168.6 2907.2 4467.6 5980.6 4886.3 9387.7 14881.1 11264.5 12247.2 23.0 3083.9 8032.6 2344.3 4005.4 1016.1 4865.3 1417.1 2900.6 9443.7 4198.0 2564.2 1411.5 2072.7 3135.4 8343.4 80.9 1771.0 2621.8 12.9 2619.8 6994.8 14038.1 5755.3 2911.9 2781.9 2412.7 5704.5 14335.9 3714.1 230.0 22.0 8424.8 2121.5 8390.5 15083.5 3384.1 2853.1 3337.3 6352.0 3321.0 5858.5 14234.5 1720.4 994.2 422.9 4461.8 207.4 583.3 6898.2 5536.5 6961.4 11607.2 3383.5 1647.5 19441.4 3123.6 4432.5 3490.6 2774.8 5183.2 2860.5 2499.5 42940.3 34738.5 50992.6 21474.2 33907.1 18326.4 18757.1 23777.1 23343.2 31253.2 16919.4 19802.1 20330.2 35862.9 18444.5 37523.3 12797.6 34088.1 86809.5 3255.7 3773.0 3539.2 4521.9 3319.4 3573.5 4064.7 3620.0 4203.0 4219.2 3591.8 4467.6 6885.8 5253.2 4939.6 35.9 6293.8 8836.3 2708.7 10515.3 296.5 332.9 2318.3 1124.2 106.9 3484.4 8003.6 6882.2 22.9 283.0 9136.2 9016.2 2181.5 17304.6 142.1 2613.2 4698.0 9239.4 1765.0 1339.1 54.3 23029.4 511.7 4800.1 2728.9 5047.4 4380.4 4646.7 6638.0 1088.5 30742.3 62.2 81.0 4883.9 14806.8 20982.2 57681.0 343.6 3932.0 17648.1 6349.9 212.7 48133.8 86.7 20882.8 19.6 102.1 25113.5 5826.4 6035.9 2541.8 3272.5 6888.7 835.1 2596.4 99.4 5732.4 1018.2 5450.7 58.2 126.3 933.7 9528.5 454.8 12719.6 3874.8 3140.6 9064.0 TNFAIP2 "B94, EXOC3L3" ENSG00000185215 "TNF alpha induced protein 2" Q03169 14 103121476-103137439 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 277.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 295.5;Langerhans cells: 198.7;monocytes: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 48.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "RT4: 785.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB004598, HPA030624" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Cytosol" "Nucleoplasm, Nuclear membrane" "CAB004598: AB_628370, HPA030624: AB_2673552" "unprognostic (5.01e-3)" "unprognostic (4.93e-2)" "unprognostic (1.56e-3)" "unprognostic (8.02e-3)" "unprognostic (3.39e-2)" "unprognostic (2.98e-2)" "unprognostic (5.52e-3)" "unprognostic (5.97e-2)" "unprognostic (1.94e-1)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (4.10e-4)" "prognostic favorable (2.79e-5)" "unprognostic (1.75e-2)" "unprognostic (3.83e-2)" "prognostic favorable (7.17e-5)" 119.9 76.8 9.0 103.6 11.5 106.8 78.4 6.7 12.2 53.8 12.1 39.8 38.0 50.9 6.6 88.3 57.1 102.2 48.3 8.0 9.7 67.7 61.6 142.4 87.4 17.1 10.4 16.9 33.6 66.8 16.6 48.4 16.2 73.6 26.8 1.6 84.0 14.9 35.0 53.3 52.5 24.8 13.6 147.9 37.4 37.1 21.4 39.5 36.8 32.5 80.3 277.5 74.6 16.1 34.7 156.3 1.1 0.6 10.1 45.9 54.5 9.7 43.2 26.4 8.9 1.6 148.7 0.3 120.3 48.5 142.5 104.2 11.6 0.0 11.9 6.1 0.6 15.4 120.0 0.7 19.2 7.7 20.0 17.8 1.6 8.4 0.1 10.5 14.2 7.7 15.5 35.3 3.6 3.4 0.4 11.6 9.7 19.6 13.4 6.8 18.9 24.9 80.8 785.1 1.3 2.3 150.2 52.4 1.9 5.6 83.8 50.4 28.4 5.1 13.5 30.3 31.5 31.4 2.4 0.9 38.1 34.0 16.1 5.9 16.8 9.0 0.1 18.6 0.1 0.1 0.1 0.0 9.4 0.2 0.1 0.1 48.4 0.2 15.0 0.5 0.0 4.5 9.0 11.5 6.7 12.2 8.0 9.7 17.1 10.4 16.2 13.6 21.4 16.1 45.8 0.0 25.1 2.3 8.2 28.3 41.8 295.5 6.8 1.1 24.2 11.4 14.1 51.5 126.1 27.6 0.0 1.2 1.3 1.0 0.0 160.9 36.8 92.4 122.2 47.1 17.3 1.7 2.5 44.7 61.2 123.3 5.6 172.8 33.7 4.5 18.9 8.0 54.1 0.0 5.7 0.3 85.5 151.2 198.7 48.8 8.4 163.3 30.2 25.3 351.9 5.9 5.2 1.0 0.9 122.1 18.3 2.2 11.7 186.0 0.7 14.4 121.5 0.7 19.7 104.9 39.7 2.1 4.6 20.7 33.4 4.8 8.3 1.1 1.9 138.6 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNFSF15 "MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A" ENSG00000181634 "TNF superfamily member 15" O95150 9 114784652-114806039 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.6;Basal squamous epithelial cells: 14.8;Endometrial ciliated cells: 15.7;Glandular and luminal cells: 28.9;Squamous epithelial cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;hTEC/SVTERT24-B: 8.6;HUVEC TERT2: 16.7;OE19: 16.0;RT4: 16.5;TIME: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012948, HPA046522" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted to blood" NA NA 1110000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA012948: AB_1858024, HPA046522: AB_2679683" "unprognostic (3.41e-1)" "unprognostic (2.06e-2)" "unprognostic (3.76e-1)" "unprognostic (1.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.67e-2)" "unprognostic (1.64e-1)" "unprognostic (2.29e-2)" "unprognostic (5.40e-2)" "unprognostic (1.38e-1)" "unprognostic (7.78e-2)" "unprognostic (2.09e-1)" "unprognostic (8.64e-5)" "unprognostic (1.97e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-3)" "unprognostic (4.46e-3)" 0.8 0.7 0.1 2.5 0.2 0.1 0.9 0.1 0.5 1.5 0.1 2.3 9.5 1.0 0.9 1.2 0.9 1.9 0.0 0.1 0.2 4.5 0.2 4.1 0.8 0.3 0.1 0.1 0.1 0.8 0.1 4.4 0.2 4.1 2.0 0.0 4.8 1.9 0.1 0.6 3.5 2.0 0.0 0.5 2.9 0.1 0.2 0.6 0.9 0.0 1.0 4.7 0.7 0.4 0.5 4.4 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.2 3.0 1.6 0.0 0.0 0.5 13.2 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 16.7 0.0 0.0 0.9 0.4 0.6 0.0 0.0 0.3 16.0 0.0 0.0 0.1 0.0 0.1 16.5 0.1 0.0 0.0 0.7 0.0 5.6 1.2 0.0 7.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.1 0.2 0.0 0.2 0.4 0.2 12.8 12.1 0.0 0.1 0.5 7.7 25.6 14.8 0.3 3.7 3.7 0.6 1.5 4.9 7.3 0.0 0.7 0.4 8.0 0.0 4.9 0.7 15.7 2.9 0.3 0.0 0.0 0.1 2.0 0.2 1.2 8.2 28.9 0.0 0.0 0.0 0.0 2.3 0.0 0.7 2.4 2.0 0.3 5.1 0.1 0.0 5.0 0.0 0.0 5.3 0.1 0.0 0.0 0.1 1.3 0.5 0.4 1.2 4.9 8.9 9.3 1.0 0.3 0.0 0.4 3.0 0.0 0.0 13.7 0.6 0.3 1.0 0.1 7.4 6.5 TNKS "ARTD5, PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555912-9782346 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.9;Excitatory neurons: 203.2;Inhibitory neurons: 230.6;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 7.3 9.3 14.2 6.5 20.5 12.2 9.9 18.5 15.8 12.1 6.9 7.5 6.0 10.5 17.5 5.9 8.2 6.2 7.0 13.4 16.8 6.1 7.5 6.6 8.5 21.5 18.5 13.1 7.5 12.5 12.6 7.9 22.2 7.8 6.8 21.0 7.1 7.7 18.4 11.4 7.8 7.1 14.7 6.5 7.2 20.3 18.3 10.5 9.7 11.8 8.6 7.9 6.9 32.2 8.8 11.5 28.8 17.4 17.8 23.7 10.7 13.4 15.1 10.7 12.0 6.9 6.9 18.9 5.4 13.2 14.3 9.2 16.5 12.5 15.4 4.9 8.6 13.3 10.7 15.6 16.0 6.9 7.9 16.9 14.8 11.1 21.6 17.3 14.6 14.5 12.7 19.6 19.9 5.8 17.5 10.4 18.9 9.7 6.7 13.9 17.8 5.5 12.8 17.8 29.1 21.4 10.5 9.9 19.3 17.3 6.6 10.2 19.7 17.4 10.6 11.9 10.0 6.7 11.8 13.3 18.7 9.5 17.1 2.4 1.1 0.9 2.0 1.1 1.0 1.9 1.6 1.9 1.4 3.2 1.8 2.2 3.5 1.5 1.4 1.8 0.8 0.7 14.2 20.5 18.5 15.8 13.4 16.8 21.5 18.5 22.2 14.7 18.3 32.2 19.7 16.0 11.7 130.9 23.1 11.5 12.8 11.4 12.0 34.1 15.8 13.6 17.0 15.7 12.0 9.2 14.6 11.2 14.9 9.2 1.9 12.4 149.9 19.9 30.6 15.5 13.8 14.5 203.2 8.5 10.9 20.3 19.9 20.9 10.1 33.7 18.9 18.0 7.1 42.1 230.6 10.8 16.2 9.4 8.5 76.3 16.8 10.3 12.4 92.8 8.4 15.1 5.2 313.1 285.7 13.4 12.8 18.0 20.7 12.8 17.2 6.9 28.1 37.0 0.0 28.7 16.6 37.7 15.4 12.9 15.5 12.3 18.1 39.5 12.2 12.8 TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8734.3;skeletal muscle: 21081.1;tongue: 12403.9" "Cell type enriched" "Detected in many" 10 "Cardiomyocytes: 3550.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "CACO-2: 68.2;CAPAN-2: 33.5;EFO-21: 65.2;HeLa: 49.1;Hep G2: 46.1;HSkMC: 67.2;U-2 OS: 97.7" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 7.6;spinal cord: 7.1" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 13: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" 8.4 10.9 0.7 0.8 0.8 0.7 19.1 2.7 1.1 7.7 7.3 4.0 1.1 2.8 41.7 387.3 2.8 3.3 8734.3 1.2 0.7 19.2 4.0 78.5 3.9 0.8 0.9 2.4 6.8 1.6 17.6 5.2 1.0 170.1 4.1 0.4 120.8 2.2 21081.1 18.9 3.3 0.8 0.8 2.8 5.7 10.6 0.8 4.3 14.4 12403.9 1.6 5.3 5.4 0.7 0.7 5.2 3.6 0.6 0.2 0.5 8.0 0.4 0.3 0.3 0.4 68.2 33.5 0.5 65.2 9.9 0.1 0.4 0.1 0.3 0.0 1.2 1.6 0.5 49.1 46.1 0.3 0.3 0.1 67.2 1.2 0.0 0.7 0.6 0.0 2.0 0.2 5.1 2.0 0.1 0.2 0.8 0.5 15.1 0.7 0.1 2.9 2.3 3.3 13.0 0.2 0.0 0.5 6.7 0.1 3.9 26.7 0.5 0.0 0.1 97.7 0.8 0.2 2.8 1.3 0.9 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.1 0.7 0.8 2.7 1.1 1.2 0.7 0.8 0.9 1.0 0.8 0.8 0.7 0.2 125.0 12.6 0.0 0.3 1.5 1.7 4.0 0.6 0.2 0.5 0.3 3550.1 5.7 7.9 3.7 2.1 59.0 0.1 1.6 27.4 11.8 0.7 66.4 6.7 39.8 330.7 0.4 0.0 13.0 5.1 52.7 0.5 98.8 0.0 0.8 0.7 0.7 4.9 0.0 0.0 1.7 2.0 0.0 1.4 5.8 22.4 2.6 5.4 0.0 0.1 1.2 0.0 0.0 0.0 6.5 0.3 177.6 0.1 0.8 0.5 1.3 2.8 0.1 0.0 241.8 36.0 2.1 1.0 0.1 0.9 31.1 2.8 1.3 2.0 6.8 TNNT1 "ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS" ENSG00000105048 "Troponin T1, slow skeletal type" P13805 19 55132698-55149206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 29 "skeletal muscle: 21567.3;tongue: 13372.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 61.2;Basal squamous epithelial cells: 47.8;Cardiomyocytes: 51.5;Skeletal myocytes: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "eosinophil: 211.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 211.5" "Cell line enhanced" "Detected in many" "HMC-1: 829.4;RH-30: 638.8" "Region enriched" "Detected in many" 5 "thalamus: 125.0" "Region enhanced" "Detected in all" "thalamus: 23.1" "CAB015168, HPA058448" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 79000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB015168: AB_2206426, HPA058448: AB_2683720" "unprognostic (1.88e-1)" "unprognostic (7.23e-2)" "prognostic unfavorable (4.66e-4)" "prognostic unfavorable (4.66e-4)" "unprognostic (3.47e-3)" "unprognostic (3.92e-3)" "unprognostic (1.35e-3)" "unprognostic (1.03e-3)" "unprognostic (2.46e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (3.23e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.91e-2)" "unprognostic (4.01e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-2)" 5.7 1.2 42.1 0.4 45.7 3.3 5.0 44.3 55.4 1.9 36.4 2.7 1.0 1.1 1.0 593.5 8.4 1.0 256.7 43.9 38.9 1.3 2.5 8.3 0.4 36.7 41.4 1.5 2.5 2.3 8.5 6.0 38.5 200.4 0.6 0.6 171.2 0.4 21567.3 48.5 2.0 0.4 35.6 1.9 1.9 10.6 40.8 3.4 3.8 13372.6 2.0 1.7 5.8 40.8 178.4 102.3 1.0 22.4 0.0 1.7 33.3 8.0 30.1 11.1 32.7 37.9 115.8 2.6 66.5 3.2 88.8 88.5 24.0 76.0 9.4 11.8 192.2 33.6 11.8 6.7 3.7 2.7 829.4 36.6 121.3 3.4 127.0 125.7 0.5 35.1 171.7 158.6 10.3 168.0 3.4 0.3 21.4 45.0 202.1 113.9 638.8 21.2 26.5 5.8 6.6 49.3 10.7 1.3 57.9 8.5 106.3 102.7 2.9 163.6 238.9 6.5 12.4 1.2 7.0 8.8 171.8 26.4 50.9 2.4 39.4 211.5 0.3 21.7 0.3 0.2 0.3 0.3 37.4 0.4 0.3 0.4 1.9 0.6 10.2 0.9 0.1 12.2 42.1 45.7 44.3 55.4 43.9 38.9 36.7 41.4 38.5 35.6 40.8 40.8 0.0 0.0 0.0 0.7 0.3 61.2 0.6 25.1 47.8 4.5 0.5 5.3 51.5 0.0 2.8 0.0 0.0 2.2 0.0 0.5 0.0 2.1 2.1 9.7 0.3 2.6 2.4 2.7 0.4 0.0 18.0 18.8 0.0 3.4 0.0 22.1 1.4 0.0 12.9 0.0 0.7 0.3 0.0 13.2 3.8 10.7 0.3 8.9 3.6 0.0 25.8 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.7 0.0 192.0 3.5 4.3 34.1 2.5 30.4 3.6 1.6 1.2 0.8 0.2 TNNT2 "CMD1D, CMH2, CMPD2" ENSG00000118194 "Troponin T2, cardiac type" P45379 1 201359008-201377764 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 205 "heart muscle: 10670.6" "Cell type enriched" "Detected in many" 32 "Cardiomyocytes: 12561.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "RH-30: 1077.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.8" "CAB015371, HPA015774, HPA017888" Enhanced Approved "Nucleoplasm,Nucleoli,Focal adhesion sites,Microtubules" No No 57000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli" "Focal adhesion sites, Microtubules" "CAB015371: AB_630390, HPA015774: AB_1858354, HPA017888: AB_1858355" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "unprognostic (2.33e-4)" "unprognostic (1.85e-1)" "unprognostic (7.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (8.63e-2)" "unprognostic (5.50e-3)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (9.98e-2)" 2.2 4.9 12.4 0.6 13.9 0.1 11.9 11.7 20.4 2.3 11.7 1.3 0.3 3.2 0.8 7.8 1.9 3.8 10670.6 16.8 11.6 51.9 2.3 22.0 2.7 11.6 11.6 1.3 5.0 0.0 4.5 10.3 11.6 6.1 0.1 0.4 3.6 0.7 16.5 21.7 1.6 0.1 11.6 0.7 2.0 1.7 11.6 2.1 2.0 9.4 0.5 19.3 5.0 15.8 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 2.0 0.4 0.0 0.5 0.0 0.0 6.7 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.5 0.0 44.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 1.1 0.0 0.0 2.2 3.3 0.0 0.0 1077.7 0.0 0.7 0.4 1.1 0.8 0.1 2.0 0.0 61.2 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 13.9 11.7 20.4 16.8 11.6 11.6 11.6 11.6 11.6 11.6 15.8 0.6 3.2 3.0 0.3 0.0 3.4 1.4 1.7 1.8 3.9 0.9 1.7 12561.8 0.0 1.1 1.8 0.0 3.5 0.0 2.3 0.0 0.4 11.6 1.2 0.2 93.3 0.0 0.0 9.4 0.4 1.2 385.3 1.1 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.5 1.7 0.0 0.0 0.8 19.3 0.6 0.3 0.0 1.9 2.6 0.0 0.0 0.5 0.7 1.2 1.4 1.2 0.0 2.1 0.8 0.9 0.7 0.6 0.0 8.7 145.8 0.5 0.2 2.5 7.2 4.2 0.1 0.8 3.2 1.5 TNPO1 "IPO2, KPNB2, MIP, MIP1, TRN" ENSG00000083312 "Transportin 1" Q92973 5 72816312-72916733 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016325 Approved Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA 130000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Cytosol, Cytoplasmic bodies" "CAB016325: AB_675691" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-3)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (6.55e-5)" "unprognostic (8.93e-3)" "unprognostic (9.03e-2)" "unprognostic (3.40e-3)" "unprognostic (2.09e-1)" "unprognostic (3.07e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "unprognostic (1.27e-2)" "unprognostic (2.49e-2)" 23.5 23.0 10.6 28.8 14.6 31.7 25.0 14.0 10.0 20.2 23.0 24.5 20.5 24.0 33.8 23.1 20.6 27.7 20.8 10.5 17.1 30.5 28.4 17.3 29.9 18.2 13.4 22.4 31.5 39.8 15.6 36.8 16.5 23.4 29.9 65.0 20.9 28.1 25.0 11.6 20.9 28.2 15.1 20.6 30.7 37.3 13.1 35.6 36.8 27.0 32.3 33.3 14.0 21.5 94.8 123.7 154.5 104.8 133.3 144.5 110.4 112.3 145.6 112.2 113.6 111.4 87.1 117.5 78.5 173.0 140.4 71.6 126.3 108.8 160.8 66.6 71.9 76.2 144.8 55.9 103.9 78.4 55.1 110.8 80.2 151.0 184.8 78.2 248.6 52.9 113.4 54.8 298.1 50.3 87.2 37.3 99.3 39.8 90.9 83.1 150.5 74.1 73.4 109.5 87.5 73.6 160.6 60.3 135.8 99.8 71.2 61.9 225.1 79.5 113.8 116.8 136.7 53.2 95.8 155.8 69.9 91.3 154.4 8.2 8.2 6.9 11.9 11.0 16.5 10.3 10.9 9.3 10.3 10.8 11.6 11.9 8.4 14.1 14.0 5.0 8.3 10.5 10.6 14.6 14.0 10.0 10.5 17.1 18.2 13.4 16.5 15.1 13.1 21.5 42.3 12.8 25.0 45.7 49.0 59.1 40.9 29.7 60.3 105.0 38.7 24.0 53.8 30.0 28.7 27.6 98.0 81.9 44.9 39.8 17.6 39.0 105.4 38.6 46.1 64.8 53.2 27.1 142.2 41.5 50.0 52.8 53.0 46.7 22.1 62.8 50.7 38.1 42.7 89.2 77.8 46.3 28.5 40.0 42.2 60.9 46.6 42.1 24.9 50.6 47.4 143.1 26.8 79.9 84.7 58.9 24.9 60.2 42.9 57.0 33.9 36.1 27.6 187.9 26.3 72.5 48.8 58.5 76.3 42.0 53.3 131.3 36.9 40.2 37.2 60.2 TNRC18 "CAGL79, KIAA1856, TNRC18A" ENSG00000182095 "Trinucleotide repeat containing 18" O15417 7 5306790-5425414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 20.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020730, HPA024251" Uncertain Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear membrane, Mitochondria" Cytosol "HPA020730: AB_2670506, HPA024251: AB_2671498" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (2.67e-3)" "unprognostic (4.44e-1)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "unprognostic (1.13e-2)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (2.11e-2)" "unprognostic (6.08e-2)" "unprognostic (1.36e-1)" "unprognostic (9.29e-3)" "unprognostic (2.14e-1)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (4.34e-2)" 30.4 18.3 10.8 29.0 8.9 51.8 30.1 16.2 14.2 40.8 2.2 56.3 25.3 57.6 16.4 26.0 43.5 22.4 22.1 10.3 0.5 22.9 19.8 32.0 16.1 6.2 1.7 46.0 29.5 35.0 22.2 30.6 1.6 36.1 22.6 12.2 28.8 34.3 24.0 33.2 29.0 36.4 1.3 25.2 33.8 22.6 5.1 17.2 32.6 11.1 14.6 40.8 31.9 3.2 72.8 63.4 51.5 43.4 42.9 50.6 133.8 50.4 47.3 27.4 29.0 26.3 62.4 49.3 48.3 74.7 60.8 79.7 30.2 60.5 23.0 21.6 19.2 31.4 56.6 43.1 37.1 104.3 111.2 51.2 70.0 54.8 63.2 39.5 31.3 43.6 45.4 27.2 35.3 120.0 24.6 127.2 4.5 47.5 48.0 27.0 25.7 37.3 22.3 91.3 22.3 53.4 38.8 102.5 37.0 23.1 106.9 106.1 78.7 78.3 109.6 47.0 36.7 38.6 44.1 46.2 44.1 72.6 94.1 14.2 3.8 3.6 1.7 1.5 1.2 2.2 1.2 1.0 1.4 2.3 0.9 1.7 20.8 3.2 2.1 5.4 1.9 0.2 10.8 8.9 16.2 14.2 10.3 0.5 6.2 1.7 1.6 1.3 5.1 3.2 25.6 9.6 29.0 59.7 7.4 9.3 3.7 9.8 13.6 51.7 15.8 25.9 7.5 14.3 12.4 14.7 2.1 14.5 20.4 33.6 1.9 5.0 14.4 22.2 29.7 17.3 31.3 9.7 40.9 6.6 3.8 17.8 19.4 36.2 14.0 48.3 29.6 25.4 11.2 50.5 45.6 30.4 8.2 41.8 12.4 18.8 18.3 22.8 5.4 71.2 25.9 31.0 11.3 32.6 20.3 9.0 10.6 19.9 12.1 6.5 7.4 5.4 11.1 4.0 19.7 18.4 21.2 0.4 2.1 12.5 8.8 10.0 12.3 18.6 25.1 3.8 TNRC6A "CAGH26, GW182, KIAA1460, TNRC6" ENSG00000090905 "Trinucleotide repeat containing adaptor 6A" Q8NDV7 16 24610209-24827632 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 289.3;Excitatory neurons: 283.8;Inhibitory neurons: 414.6;Oligodendrocyte precursor cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015305, HPA017869" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA015305: AB_1850454, HPA017869: AB_1850456" "unprognostic (2.64e-1)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (1.10e-3)" "unprognostic (1.62e-1)" "unprognostic (3.22e-3)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (7.44e-3)" "unprognostic (2.63e-3)" "unprognostic (1.78e-1)" "unprognostic (9.18e-2)" "unprognostic (5.77e-2)" "unprognostic (2.31e-1)" "unprognostic (3.35e-2)" 17.2 21.0 5.0 6.4 3.6 6.0 14.9 10.8 7.1 17.8 6.1 17.8 5.5 23.5 11.5 11.3 17.7 6.4 11.1 3.4 6.6 10.3 13.0 12.8 7.1 6.1 4.8 20.6 19.2 13.2 22.8 6.6 6.1 14.6 6.4 7.0 14.9 8.0 14.0 13.1 15.3 8.1 2.2 9.9 15.2 6.6 7.0 8.6 17.8 6.9 7.4 13.0 13.4 7.4 10.1 13.8 16.0 8.7 13.6 17.7 9.1 16.9 13.6 12.0 13.1 10.2 8.2 10.2 7.1 17.0 12.4 11.2 20.1 14.2 18.0 10.4 10.4 10.2 16.7 14.1 11.7 10.5 6.9 18.0 7.3 15.8 10.2 14.8 16.7 6.6 15.7 6.2 15.8 11.9 8.8 6.9 23.1 4.9 6.8 17.1 12.4 9.1 9.1 9.3 7.7 10.8 11.8 7.2 6.6 12.1 8.4 6.8 15.5 15.3 10.5 7.6 12.0 13.7 11.6 16.5 14.3 6.4 11.3 0.5 0.5 0.4 0.5 0.3 0.4 1.1 0.5 0.5 0.2 1.0 0.7 0.5 0.3 0.6 0.3 1.0 0.5 0.3 5.0 3.6 10.8 7.1 3.4 6.6 6.1 4.8 6.1 2.2 7.0 7.4 51.2 38.5 60.0 289.3 45.5 34.9 17.8 21.9 39.9 97.1 42.8 41.0 75.3 51.5 32.3 46.0 118.9 22.4 49.9 38.3 17.6 23.6 17.2 38.7 65.5 45.5 55.9 34.9 283.8 24.5 15.1 50.5 33.6 42.8 39.3 76.5 60.3 115.3 21.2 176.7 414.6 36.3 22.4 56.2 26.5 11.3 69.0 28.7 30.2 138.7 36.1 42.0 50.4 265.4 234.2 28.5 36.1 81.3 44.7 26.0 42.8 19.2 29.8 81.7 19.7 52.8 60.9 41.2 30.6 38.1 28.7 8.2 39.0 36.5 35.8 17.4 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 TOMM34 "HTOM34P, TOM34" ENSG00000025772 "Translocase of outer mitochondrial membrane 34" Q15785 20 44942130-44960397 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 119.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.3;monocytes: 176.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018845, HPA056875" Enhanced Supported Vesicles,Mitochondria,Cytosol NA NA 26000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "Vesicles, Mitochondria" "HPA018845: AB_1858184, HPA056875: AB_2683264" "unprognostic (4.96e-2)" "unprognostic (6.88e-2)" "unprognostic (5.05e-2)" "unprognostic (1.36e-3)" "unprognostic (4.91e-2)" "prognostic unfavorable (4.47e-5)" "prognostic unfavorable (8.71e-6)" "unprognostic (2.55e-1)" "unprognostic (5.04e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (2.11e-2)" "unprognostic (1.55e-2)" "unprognostic (3.04e-1)" "unprognostic (1.02e-1)" "prognostic favorable (5.45e-4)" "unprognostic (5.79e-3)" 13.4 46.0 31.4 13.6 40.3 20.1 14.6 24.3 51.7 14.5 28.3 14.6 11.8 14.8 49.0 19.5 49.1 13.6 16.0 54.6 32.6 28.6 18.8 14.0 15.2 29.0 26.1 26.4 18.0 24.4 26.6 29.6 28.0 18.8 18.4 9.0 15.7 16.9 18.0 14.6 13.7 15.4 24.7 14.9 15.8 119.4 33.6 18.3 16.5 15.2 22.0 26.2 12.7 35.7 133.6 46.0 40.1 85.6 36.3 35.6 90.2 75.6 109.6 92.8 67.1 187.4 48.6 90.9 63.5 59.6 94.2 82.1 98.8 164.0 107.3 16.1 46.2 71.7 58.2 133.7 46.2 47.5 42.3 38.7 45.2 129.8 230.8 80.9 95.8 36.6 82.6 36.4 89.3 88.2 50.2 65.4 47.1 70.7 172.8 43.1 42.2 98.9 76.1 73.7 68.3 40.4 103.5 71.0 91.8 30.7 53.5 40.8 57.2 121.5 80.0 58.9 114.8 31.2 40.1 75.4 110.9 55.8 48.2 15.9 16.9 15.3 14.8 17.5 15.4 25.4 15.3 15.7 39.7 28.6 17.1 13.7 4.6 14.8 18.8 21.1 19.3 17.3 31.4 40.3 24.3 51.7 54.6 32.6 29.0 26.1 28.0 24.7 33.6 35.7 7.3 6.4 11.5 3.6 15.0 13.8 84.6 17.2 14.8 3.1 14.1 11.2 10.3 5.7 15.5 12.9 4.2 128.3 8.7 7.7 31.3 38.4 18.5 17.5 7.2 13.0 12.0 17.2 6.8 30.7 38.0 14.8 16.8 14.8 9.5 28.2 6.4 9.1 22.7 3.3 4.8 9.3 8.2 5.9 47.2 32.9 6.8 10.3 7.2 5.6 176.9 17.4 7.2 3.5 2.7 46.2 9.5 6.4 16.9 69.1 6.9 22.5 44.3 4.2 0.0 5.6 13.6 43.0 56.2 15.7 11.1 56.5 8.8 24.0 13.6 55.9 TOX4 "C14orf92, KIAA0737, LCP1" ENSG00000092203 "TOX high mobility group box family member 4" O94842 14 21476597-21499175 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017880, HPA027551" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA017880: AB_1845573, HPA027551: AB_10601701" "unprognostic (9.56e-2)" "unprognostic (2.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.46e-2)" "unprognostic (9.30e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (3.46e-4)" "unprognostic (8.05e-3)" "unprognostic (2.58e-1)" "unprognostic (5.00e-2)" "unprognostic (3.23e-2)" "unprognostic (2.94e-1)" "prognostic favorable (8.38e-5)" "unprognostic (1.84e-1)" "unprognostic (2.48e-1)" "unprognostic (9.03e-2)" "unprognostic (2.48e-3)" 16.7 14.6 17.3 14.1 17.6 21.4 16.3 17.9 20.1 18.0 14.8 18.5 12.6 15.4 15.1 21.1 14.7 12.2 21.9 17.5 17.7 15.0 15.7 15.9 15.1 17.1 18.7 15.9 15.8 20.4 13.6 15.5 17.5 14.7 15.2 16.1 14.8 17.4 55.5 21.5 14.8 19.7 16.8 13.7 16.9 14.3 18.3 26.1 17.1 25.8 21.3 17.4 16.0 19.5 27.1 27.4 22.7 21.5 32.1 30.6 30.3 25.3 49.6 52.7 50.3 27.0 31.6 16.2 17.5 41.5 42.0 31.5 37.4 38.8 66.8 28.6 15.1 18.1 17.7 37.8 41.5 33.6 28.7 40.0 39.8 41.7 39.4 35.9 38.0 30.1 22.6 27.4 37.9 22.8 33.4 19.3 12.8 39.5 43.2 29.7 23.7 18.6 24.5 33.4 20.9 21.5 25.0 26.3 21.3 29.8 24.8 12.6 25.0 27.2 24.9 24.1 22.5 35.1 41.7 36.9 12.8 16.4 28.7 40.9 27.4 40.0 23.1 29.2 25.0 24.0 20.5 22.2 26.0 24.9 21.3 24.4 48.6 29.2 27.5 33.7 31.7 28.9 17.3 17.6 17.9 20.1 17.5 17.7 17.1 18.7 17.5 16.8 18.3 19.5 60.0 67.3 64.0 0.0 43.3 87.3 63.9 81.3 58.1 75.0 50.4 42.0 51.8 42.9 64.4 46.0 29.2 73.5 69.3 51.0 62.6 47.3 76.1 42.6 46.9 53.4 68.9 48.8 0.0 51.4 64.1 48.4 40.8 50.4 61.4 41.4 37.9 43.1 43.8 42.1 0.0 45.4 52.9 41.3 61.6 36.5 48.7 46.1 39.2 0.0 55.3 40.4 46.4 0.0 0.0 51.4 51.9 44.0 44.4 59.0 91.4 64.0 57.4 54.5 32.9 54.1 58.6 131.9 66.8 50.5 88.8 265.8 62.0 55.5 43.8 70.0 TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Mitochondria, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" 19.3 13.8 10.4 27.1 12.6 19.6 22.5 10.4 16.5 19.9 10.3 29.0 18.9 24.5 12.8 28.8 31.3 13.2 11.1 10.1 11.4 14.9 16.5 15.1 34.6 18.7 13.6 27.3 18.3 9.4 7.3 23.5 12.5 17.7 27.5 4.1 18.9 15.3 12.3 37.4 20.4 24.6 12.6 31.1 22.6 10.4 12.3 47.2 17.4 6.1 45.4 20.8 19.9 13.3 81.5 145.3 81.1 57.3 37.3 43.9 82.8 28.4 66.1 78.5 100.2 4.2 40.6 190.5 126.9 58.7 77.6 174.9 119.7 80.4 72.8 42.7 76.5 77.6 76.8 70.9 111.5 1.6 37.0 55.7 93.0 38.9 106.5 45.6 79.4 24.7 3.8 6.9 41.5 145.1 130.0 96.3 80.2 10.4 2.4 252.2 56.1 66.2 59.4 87.3 46.0 80.5 94.1 62.6 24.3 39.4 109.2 7.4 100.7 91.6 30.2 1.0 48.3 47.6 37.9 82.5 23.6 9.7 80.1 1.2 21.2 3.4 13.0 21.7 15.9 21.5 13.3 14.6 30.3 19.1 13.7 15.4 2.4 17.5 19.3 27.3 17.3 14.7 10.4 12.6 10.4 16.5 10.1 11.4 18.7 13.6 12.5 12.6 12.3 13.3 21.1 9.6 12.8 16.3 26.0 28.7 14.5 24.6 24.5 2.6 36.1 30.4 2.5 18.6 15.4 20.2 0.0 36.9 24.7 16.9 9.8 24.8 12.8 11.5 29.0 24.5 30.7 21.7 2.1 18.1 39.6 17.0 11.2 19.5 1.3 31.7 22.1 18.0 24.2 0.0 3.2 43.0 18.3 27.8 20.1 3.8 23.0 19.3 12.4 7.5 31.9 4.9 25.7 9.0 8.0 15.8 16.4 17.0 7.8 15.7 10.3 10.1 8.8 2.6 13.1 25.9 20.6 0.5 4.9 28.7 32.8 22.4 16.5 27.4 54.1 11.5 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Supported "Nucleoplasm,Nuclear bodies,Mitotic chromosome,Vesicles" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "Nucleoplasm, Mitotic chromosome, Vesicles" "CAB004083: AB_10694558, CAB079980: , HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 6.9 11.5 17.4 10.1 16.6 11.5 10.7 19.9 14.5 17.7 21.5 9.7 6.4 16.0 15.9 6.1 14.7 10.7 8.8 15.4 26.3 9.1 4.1 8.3 8.6 13.5 16.7 16.8 7.4 22.3 24.1 12.2 15.7 12.1 10.2 22.0 10.1 12.8 7.2 9.2 6.4 16.3 9.6 8.7 7.6 21.6 23.0 15.3 17.9 11.0 12.6 11.2 8.7 12.1 13.5 22.3 63.8 40.1 25.8 31.9 15.8 22.8 33.8 31.0 39.1 19.4 15.8 14.5 19.2 39.0 66.9 32.4 46.3 27.5 36.8 38.9 15.8 27.1 40.1 11.7 16.8 30.2 37.4 24.9 19.0 41.8 31.2 51.7 37.4 24.2 26.9 12.3 36.5 9.6 23.7 14.1 41.1 24.2 13.9 25.1 23.9 9.3 22.9 31.8 57.3 26.8 33.8 14.3 8.5 48.6 29.9 16.9 27.5 33.7 22.3 27.0 20.5 9.8 22.4 33.0 27.6 14.6 17.5 1.4 0.5 1.0 1.6 0.7 1.3 1.9 1.6 1.6 1.2 1.8 1.8 1.6 0.6 0.9 0.5 1.3 1.4 0.7 17.4 16.6 19.9 14.5 15.4 26.3 13.5 16.7 15.7 9.6 23.0 12.1 11.5 22.4 22.3 53.2 17.8 6.4 10.2 10.0 13.6 32.4 17.4 13.2 14.9 5.7 20.8 29.5 47.9 13.4 11.1 7.4 9.8 14.5 38.8 47.0 44.8 16.8 41.9 8.4 66.2 7.1 11.2 23.9 14.8 26.8 26.6 47.0 15.0 3.3 10.8 47.1 81.9 15.7 12.2 3.8 6.9 17.8 23.6 9.3 1.8 17.8 4.0 11.9 7.2 62.8 50.4 7.5 5.8 17.7 17.1 11.0 2.6 8.8 60.7 51.7 13.1 35.2 20.5 33.1 36.2 14.7 5.3 18.5 17.0 29.9 13.4 8.9 TP53TG5 "C20orf10, CLG01, dJ453C12.5" ENSG00000124251 "TP53 target 5" Q9Y2B4 20 45372557-45407889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 17.8" "Cell type enhanced" "Detected in some" "Early spermatids: 671.5;Late spermatids: 254.4;Oligodendrocytes: 157.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041979, HPA058510, HPA077455" Enhanced Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA041979: AB_2677778, HPA058510: , HPA077455: " "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.29e-3)" "unprognostic (3.10e-3)" "unprognostic (9.26e-2)" "unprognostic (3.56e-2)" "unprognostic (1.72e-5)" "unprognostic (2.09e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.72e-4)" "unprognostic (1.41e-1)" 0.1 0.1 1.1 0.2 1.8 0.7 0.1 0.9 2.6 0.1 1.4 0.3 0.1 0.2 0.4 0.1 0.2 0.2 0.2 1.1 1.5 0.1 0.1 0.2 0.4 1.8 1.5 0.1 0.1 0.0 0.2 0.1 2.0 0.1 0.0 0.8 0.2 0.0 0.2 0.2 0.2 0.0 0.7 0.2 0.2 17.8 1.7 0.0 0.2 0.0 0.0 0.2 0.1 3.5 0.3 0.7 0.4 1.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.1 0.3 0.3 0.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.3 0.4 1.0 0.6 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.1 0.0 0.5 0.4 0.3 0.1 0.3 0.3 0.0 0.2 0.2 0.0 0.4 0.4 0.3 1.0 0.4 0.2 0.1 1.1 0.1 0.6 1.4 0.4 0.9 0.2 0.3 0.4 0.0 0.7 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.8 0.9 2.6 1.1 1.5 1.8 1.5 2.0 0.7 1.7 3.5 0.1 0.0 0.0 2.9 0.0 0.1 0.4 0.0 0.0 0.8 0.5 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 671.5 0.5 0.2 0.3 0.0 0.0 7.6 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.8 0.5 0.0 0.0 1.1 254.4 4.7 0.1 0.0 1.9 0.0 0.1 0.0 2.5 157.5 0.0 1.2 4.5 0.0 0.2 0.2 0.1 0.3 1.0 0.0 0.4 1.2 2.1 1.8 0.0 1.1 0.0 0.1 0.0 0.3 0.9 TPD52L1 "D53, hD53, TPD53" ENSG00000111907 "TPD52 like 1" Q16890 6 125119049-125264407 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.3;salivary gland: 298.3" "Cell type enhanced" "Detected in many" "Astrocytes: 390.1;Squamous epithelial cells: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 269.1;hTCEpi: 234.3;MCF7: 365.5;RPTEC TERT1: 271.4;SK-BR-3: 189.4;T-47d: 162.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027915, HPA027916" Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions, Cytosol" "HPA027915: AB_10602074, HPA027916: AB_10601860" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (2.76e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (2.87e-2)" "unprognostic (1.38e-2)" "unprognostic (2.14e-1)" "unprognostic (7.85e-2)" "unprognostic (7.80e-2)" "unprognostic (9.42e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (5.34e-4)" 44.7 258.3 83.9 10.1 96.2 0.8 67.0 72.6 97.4 35.8 103.4 36.2 9.7 15.2 68.8 152.4 34.6 27.3 71.4 78.4 81.3 40.6 58.4 10.9 6.6 81.4 76.8 20.7 47.1 67.3 24.8 8.9 78.8 41.0 13.0 1.9 298.3 79.1 111.9 47.9 10.6 12.3 68.5 2.0 43.1 5.1 81.5 3.4 60.7 126.2 12.3 59.6 60.8 76.6 37.7 42.0 0.5 269.1 2.4 0.6 63.3 6.2 5.9 0.0 0.7 67.3 46.9 0.1 136.2 31.2 9.1 83.8 8.4 58.2 0.2 0.8 58.0 0.8 58.0 0.5 5.7 0.2 0.1 7.4 234.3 0.1 30.7 82.5 0.0 0.0 30.5 0.6 4.7 365.5 0.0 0.7 4.4 36.8 22.7 0.4 0.1 0.0 271.4 9.8 9.1 0.2 70.5 189.4 4.6 9.6 162.3 0.8 0.2 1.8 5.9 0.5 2.0 0.1 0.1 0.2 1.0 0.3 0.7 1.8 0.5 0.3 0.3 0.2 0.3 0.3 0.6 0.2 0.2 0.4 0.7 0.5 2.7 2.6 0.1 0.4 0.2 0.4 83.9 96.2 72.6 97.4 78.4 81.3 81.4 76.8 78.8 68.5 81.5 76.6 141.6 0.0 28.3 390.1 2.2 19.6 44.6 70.2 128.1 3.8 164.4 154.9 45.8 25.8 51.7 125.0 4.2 32.7 3.2 3.9 176.1 30.7 6.9 71.7 21.1 87.2 16.2 0.0 16.4 110.8 140.2 18.8 13.7 184.5 2.5 29.5 15.4 59.9 10.9 0.0 48.2 11.3 83.4 2.1 5.2 4.9 17.4 3.4 131.6 28.1 0.6 3.9 1.0 11.6 2.9 35.3 2.3 36.5 2.6 37.1 10.9 45.4 15.7 1.3 0.0 177.1 10.1 5.7 9.2 272.2 37.2 14.4 3.5 53.8 17.8 19.2 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRA2A "AWMS1, htra-2-alpha" ENSG00000164548 "Transformer 2 alpha homolog" Q13595 7 23504780-23532041 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054018 Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoli "Nucleoplasm, Vesicles" "HPA054018: AB_2682344" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.24e-1)" "unprognostic (6.77e-3)" "unprognostic (8.05e-2)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.28e-2)" "unprognostic (2.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.87e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (1.79e-6)" "unprognostic (1.46e-2)" "unprognostic (1.52e-2)" "unprognostic (8.74e-2)" "unprognostic (1.36e-3)" 35.1 39.1 55.7 37.0 58.2 113.4 32.1 57.4 75.7 47.1 57.9 38.7 26.4 42.8 43.9 47.3 42.7 21.3 30.4 55.3 57.8 45.9 34.9 33.5 47.6 57.2 56.5 53.1 32.6 25.6 40.4 32.9 57.6 41.3 39.2 42.0 33.2 22.1 23.1 42.8 36.8 41.0 56.6 52.8 33.0 30.9 56.8 46.1 35.9 21.3 53.6 37.9 42.9 64.9 57.2 61.2 94.1 148.4 49.1 30.9 60.4 71.4 33.6 70.5 57.4 51.2 76.4 107.4 39.9 53.7 82.3 92.1 115.6 66.9 88.4 64.6 65.7 65.9 67.9 81.8 52.0 78.0 59.2 37.1 44.9 53.1 66.1 62.7 80.9 46.7 129.5 51.0 79.7 55.6 96.5 128.7 84.5 69.5 62.5 106.1 74.8 64.3 81.8 81.0 80.7 65.8 66.0 75.8 49.8 69.1 59.6 85.5 73.8 55.4 79.0 51.0 83.4 56.6 76.1 86.9 47.7 103.8 75.3 16.8 17.1 23.6 24.6 28.8 21.6 17.6 23.3 23.1 20.6 16.1 19.6 23.7 25.4 19.1 27.0 30.0 25.2 10.2 55.7 58.2 57.4 75.7 55.3 57.8 57.2 56.5 57.6 56.6 56.8 64.9 110.6 60.9 72.2 112.3 141.9 104.4 95.6 61.7 94.4 54.5 118.5 74.8 42.5 60.1 60.8 88.3 52.1 83.2 153.3 84.9 25.4 54.8 62.1 155.7 137.1 74.8 118.5 77.5 113.1 43.9 84.6 91.5 89.2 166.7 86.7 62.5 84.6 71.4 54.8 37.0 115.4 100.3 48.8 89.5 125.4 23.7 65.0 88.9 56.9 107.7 71.5 48.1 70.0 203.1 245.1 59.2 92.0 67.7 125.4 97.7 59.7 41.8 71.3 101.8 72.3 119.2 88.2 99.8 65.0 138.6 113.1 117.9 130.4 49.1 112.6 92.1 TRAF4 "CART1, MLN62, RNF83" ENSG00000076604 "TNF receptor associated factor 4" Q9BUZ4 17 28744005-28750956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Urothelial cells: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 54.0" "Lineage enriched" "Detected in all" 6 "dendritic cells: 54.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009055, HPA021904, HPA052377" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB009055: AB_2209701, HPA021904: , HPA052377: AB_2681804" "unprognostic (1.77e-1)" "unprognostic (9.05e-2)" "unprognostic (1.31e-2)" "unprognostic (2.51e-3)" "unprognostic (1.76e-1)" "unprognostic (7.38e-3)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (7.55e-2)" "unprognostic (1.74e-3)" "unprognostic (6.98e-2)" "unprognostic (9.26e-2)" "unprognostic (2.77e-2)" "unprognostic (5.58e-3)" 10.7 19.4 16.1 11.2 17.8 31.2 19.3 15.6 19.1 10.9 18.4 28.4 47.1 9.1 4.1 28.6 14.4 20.3 5.2 15.5 15.5 45.0 60.1 22.7 18.8 18.6 17.7 12.2 32.1 4.0 14.5 16.4 17.0 31.4 22.2 3.6 46.8 6.9 1.8 15.4 38.7 5.1 15.6 19.0 35.9 15.1 16.3 13.6 29.1 0.8 20.1 36.7 11.8 23.9 41.2 62.7 85.3 41.6 12.0 13.9 131.2 27.3 22.8 28.2 37.2 50.2 50.0 62.5 38.8 29.9 19.0 61.0 39.1 61.5 11.6 20.3 58.5 22.5 111.7 58.3 45.9 10.9 25.0 26.5 59.2 33.2 39.7 25.5 22.2 29.1 60.1 5.4 26.1 67.3 34.6 22.7 65.9 80.2 14.4 52.1 38.8 30.6 80.8 115.7 53.2 61.3 42.0 181.7 84.3 73.4 69.5 17.2 15.0 17.8 37.4 20.3 39.2 8.2 21.3 80.1 14.0 17.8 81.9 5.7 0.5 1.9 1.0 1.1 2.6 9.7 1.8 1.9 2.9 9.3 1.3 1.3 0.2 1.8 0.9 54.0 1.0 1.8 16.1 17.8 15.6 19.1 15.5 15.5 18.6 17.7 17.0 15.6 16.3 23.9 9.3 22.4 28.3 28.4 59.2 137.5 185.0 58.2 122.3 3.4 134.8 100.1 0.4 44.3 66.7 20.2 6.2 107.9 88.3 121.3 43.0 78.5 53.4 102.8 22.8 20.7 84.1 4.8 0.9 109.2 136.8 20.4 83.1 133.7 7.0 10.1 8.9 38.1 13.9 8.4 1.6 81.6 61.1 2.2 71.9 12.1 3.7 16.0 39.2 3.7 7.3 23.0 5.2 37.7 19.8 128.0 125.7 1.5 36.6 219.0 155.7 33.8 68.7 2.3 0.0 9.8 34.9 5.8 22.6 57.7 78.6 124.4 31.5 14.5 93.5 346.4 TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.8;Erythroid cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: AB_1858238, HPA062163: AB_2684702" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.08e-2)" "unprognostic (2.24e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "prognostic favorable (7.42e-5)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "unprognostic (9.82e-3)" 24.1 20.3 53.2 16.4 63.7 52.2 14.8 61.2 60.9 16.1 55.6 22.4 13.4 14.3 13.0 16.7 13.9 18.7 70.9 47.3 54.0 23.7 14.1 20.7 17.3 92.9 67.6 9.7 15.4 26.6 12.4 23.7 86.8 12.8 22.8 20.1 26.4 15.2 14.8 8.1 16.1 20.4 99.9 18.1 12.2 7.8 69.7 12.4 34.9 26.8 13.6 15.7 9.0 102.2 11.6 15.5 9.4 34.3 61.6 87.4 10.6 39.2 32.8 27.4 31.9 24.4 9.8 7.1 16.3 50.6 26.4 11.2 20.0 12.9 43.5 21.4 13.0 15.5 25.6 15.9 33.8 12.3 18.4 48.4 10.8 28.8 22.2 27.5 40.4 11.0 12.4 26.9 55.8 16.6 9.6 6.9 10.6 11.3 32.7 12.1 24.9 10.6 21.9 15.6 18.6 24.0 21.0 15.5 63.6 13.6 12.4 12.4 50.2 44.2 16.6 31.0 25.7 16.2 30.2 8.3 37.2 18.2 24.4 2.6 5.5 6.2 7.8 7.0 7.3 9.3 10.1 6.7 4.3 14.2 6.9 7.3 3.4 11.1 6.5 2.3 12.6 6.0 53.2 63.7 61.2 60.9 47.3 54.0 92.9 67.6 86.8 99.9 69.7 102.2 34.0 16.0 29.8 37.5 17.8 8.3 3.4 6.3 11.4 45.4 14.4 8.8 157.8 22.8 13.4 9.2 73.0 10.3 9.3 27.9 7.9 13.9 1.9 12.7 20.9 21.0 29.5 181.0 92.3 14.7 4.8 16.9 10.7 25.7 19.6 10.3 15.0 14.3 10.6 77.4 75.6 20.6 10.2 12.9 7.7 3.8 8.1 13.2 26.6 22.5 14.2 5.1 12.3 47.7 57.0 10.7 14.5 12.8 16.8 5.7 21.7 8.9 14.9 22.1 13.1 23.2 23.3 9.4 12.8 16.2 4.1 5.6 16.6 18.7 24.5 7.2 TRAPPC2 "hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L" ENSG00000196459 "Trafficking protein particle complex 2" P0DI81 X 13712244-13734635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004665, HPA063308" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "CAB004665: AB_425678, HPA063308: AB_2684982" "unprognostic (1.97e-1)" "prognostic favorable (8.09e-4)" "unprognostic (2.13e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-3)" "unprognostic (1.76e-2)" "prognostic favorable (6.35e-4)" "unprognostic (3.50e-2)" "unprognostic (8.24e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (2.36e-1)" "prognostic favorable (7.89e-5)" 6.0 5.7 12.5 6.7 13.4 7.6 6.8 13.1 14.2 10.0 10.7 10.9 6.0 11.0 6.3 8.4 9.4 5.5 5.3 13.3 13.9 7.4 8.2 7.5 12.7 12.1 11.2 11.2 9.2 5.2 7.7 5.3 12.5 8.3 6.4 10.2 7.3 5.1 4.4 7.4 9.6 8.8 10.2 10.3 9.7 3.2 14.9 9.0 7.8 2.7 11.8 8.9 9.9 11.8 9.1 6.2 10.5 26.1 8.0 5.9 3.7 8.5 7.8 6.7 6.9 5.8 11.0 14.8 13.2 6.9 8.8 11.0 13.8 12.4 8.6 15.3 20.4 11.3 16.0 5.2 6.4 15.9 20.8 8.0 7.0 14.7 17.1 13.4 6.3 11.1 15.0 26.3 7.3 16.0 16.0 21.7 10.6 7.2 11.4 15.3 14.3 14.6 10.8 5.5 10.6 13.6 14.5 12.1 11.0 16.3 13.5 10.6 7.9 6.7 6.2 11.4 5.5 13.3 13.8 19.6 6.0 10.5 6.4 19.3 6.0 11.0 18.1 8.4 18.2 13.2 14.3 17.8 5.5 12.8 11.8 16.6 11.7 22.9 6.9 13.0 18.7 11.1 12.5 13.4 13.1 14.2 13.3 13.9 12.1 11.2 12.5 10.2 14.9 11.8 8.9 9.6 6.5 7.8 22.0 15.2 10.0 14.8 9.6 16.5 16.5 13.6 11.0 15.7 14.6 9.2 12.5 14.1 49.8 14.6 21.5 10.0 17.7 17.3 11.0 9.3 12.1 12.4 20.7 13.4 19.9 11.5 14.8 21.2 9.5 16.9 16.8 12.2 11.6 20.2 20.2 14.0 8.2 12.9 14.4 6.1 12.8 13.6 8.8 10.3 12.0 8.8 44.3 31.7 17.3 15.7 18.6 11.3 17.6 9.8 15.4 23.8 8.5 14.5 6.6 8.6 18.5 4.3 4.0 11.3 17.6 17.9 28.8 16.6 13.2 12.5 TRAPPC2B "MIP-2A, SEDLP, SEDLP1, TRAPPC2P1" ENSG00000256060 "Trafficking protein particle complex 2B" P0DI82 19 57363551-57365405 "Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063308 Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA063308: AB_2684982" "unprognostic (8.55e-2)" "unprognostic (1.07e-2)" "unprognostic (4.24e-1)" "unprognostic (5.27e-2)" "unprognostic (1.93e-1)" "unprognostic (6.69e-2)" "unprognostic (1.12e-1)" "unprognostic (4.47e-2)" "unprognostic (4.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.26e-1)" "unprognostic (4.49e-2)" "unprognostic (9.74e-2)" "unprognostic (1.39e-2)" 15.0 20.6 8.3 6.8 8.8 10.6 14.2 10.6 11.5 7.9 9.5 13.0 5.0 10.6 11.0 12.5 9.8 9.8 19.5 8.5 9.5 12.5 11.0 10.4 12.3 8.4 8.6 12.8 7.3 10.8 14.9 10.8 9.0 10.1 5.7 8.6 10.9 6.7 30.2 11.6 8.6 9.2 8.2 13.3 9.5 23.2 8.9 15.2 12.2 17.0 10.7 12.4 8.5 8.6 16.9 11.9 18.0 12.0 16.2 18.9 16.2 11.5 25.9 16.6 48.6 6.4 12.5 13.0 15.3 14.9 28.3 6.1 8.4 18.5 17.8 5.9 60.8 13.0 18.7 14.6 16.7 14.3 20.9 18.9 23.1 12.6 9.4 19.1 12.5 14.5 4.1 0.1 19.5 5.0 22.1 13.0 6.0 1.2 25.3 10.7 17.0 20.2 18.8 26.7 18.8 15.4 10.9 12.5 11.1 15.9 18.7 18.1 13.9 15.8 13.7 7.7 18.6 20.5 27.8 25.4 22.7 9.1 16.0 68.4 23.5 30.8 12.0 22.2 24.6 45.1 25.3 20.2 26.5 48.5 24.4 19.5 27.7 44.1 20.9 37.9 24.6 22.4 8.3 8.8 10.6 11.5 8.5 9.5 8.4 8.6 9.0 8.2 8.9 8.6 38.9 9.6 13.1 0.0 13.2 0.0 0.0 0.0 0.0 0.0 21.7 28.2 26.1 0.0 9.9 18.4 0.0 38.1 16.3 0.0 25.4 32.9 0.0 29.3 13.4 15.4 0.0 0.0 0.0 22.1 18.3 10.3 0.0 25.7 21.5 18.2 0.0 0.0 32.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 11.9 0.0 0.0 0.0 0.0 28.7 0.0 0.0 4.4 0.0 0.0 17.0 13.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 91.9 11.7 32.7 0.0 0.0 TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 89.5;Excitatory neurons: 121.8;Inhibitory neurons: 136.3;Late spermatids: 119.0;Microglial cells: 105.9;Oligodendrocyte precursor cells: 93.5;Oligodendrocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA026579: AB_1854459" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "prognostic favorable (5.11e-6)" "unprognostic (2.09e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.62e-1)" 8.6 13.4 10.3 6.9 11.0 11.1 8.9 10.7 12.7 10.3 12.5 11.1 8.0 11.3 5.1 12.3 12.2 5.8 15.0 10.8 10.3 13.8 11.6 9.5 8.0 13.1 14.1 10.5 11.9 27.4 20.7 7.2 13.9 11.7 6.0 14.2 11.6 8.3 33.5 11.4 10.9 7.2 10.2 11.3 12.5 9.0 11.9 11.3 12.9 17.6 6.8 11.1 10.8 13.0 9.6 16.6 7.4 20.8 15.5 9.0 4.9 6.0 9.9 3.1 5.0 6.2 11.2 11.6 14.0 11.9 4.7 12.2 10.0 9.4 3.4 16.8 6.1 18.6 9.8 6.2 11.2 4.7 14.5 8.9 9.3 2.5 7.9 11.1 12.9 13.1 6.7 10.1 5.1 27.0 29.2 6.2 2.3 31.3 14.0 12.2 2.7 19.4 11.6 11.6 19.1 10.6 9.8 4.7 10.6 7.6 15.3 6.8 7.7 4.6 7.9 10.8 4.9 14.1 10.9 7.8 9.6 10.1 7.4 15.4 3.5 2.9 4.2 3.3 4.6 2.7 2.9 3.3 3.5 4.4 2.8 3.6 5.0 4.9 3.4 4.2 2.1 3.5 10.3 11.0 10.7 12.7 10.8 10.3 13.1 14.1 13.9 10.2 11.9 13.0 5.1 3.2 8.3 89.5 9.6 2.3 4.7 3.1 5.7 14.2 5.5 4.1 13.9 5.7 5.3 11.0 20.9 10.9 5.4 15.2 9.8 6.5 47.9 8.4 3.7 6.5 30.5 3.4 121.8 6.2 4.4 5.3 29.6 10.2 8.8 7.9 4.6 9.2 7.5 28.6 136.3 14.4 10.2 10.5 3.7 119.0 5.9 10.3 10.6 105.9 5.3 13.6 11.3 93.5 170.6 5.1 6.6 7.9 11.0 3.7 13.4 19.9 15.7 13.7 6.6 9.0 5.3 3.6 6.6 8.7 3.0 14.6 10.5 8.6 12.0 5.4 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TREML1 "dJ238O23.3, TLT1" ENSG00000161911 "Triggering receptor expressed on myeloid cells like 1" Q86YW5 6 41149342-41154337 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;brain: 4.5;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 7 "Macrophages: 75.6;monocytes: 28.3" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 92.4" "Lineage enriched" "Detected in many" 49 "granulocytes: 92.4" "Cell line enriched" "Detected in single" 170 "HEL: 66.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016700, HPA017860" Enhanced Uncertain "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA 43000000 "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles, Cytosol" "Golgi apparatus, Plasma membrane" "HPA016700: AB_1858262, HPA017860: AB_1858261" "unprognostic (6.70e-2)" "unprognostic (3.50e-3)" "unprognostic (1.15e-3)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (4.53e-5)" "unprognostic (1.10e-2)" "unprognostic (2.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.12e-3)" "unprognostic (2.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.11e-4)" "unprognostic (1.36e-1)" "unprognostic (8.38e-2)" "unprognostic (7.51e-2)" "unprognostic (3.41e-2)" 0.9 1.0 1.7 2.7 2.1 8.7 0.5 2.2 4.5 0.3 1.3 0.3 0.0 0.1 0.4 0.1 0.4 0.9 0.3 1.9 2.5 0.2 0.3 2.1 5.4 3.3 2.4 0.1 0.4 0.2 0.4 0.5 2.8 0.2 0.9 0.2 0.4 0.3 0.1 0.3 0.4 0.2 2.5 7.3 0.2 0.1 3.6 4.1 0.3 0.5 4.8 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.4 1.7 2.8 0.2 1.8 0.4 0.2 0.1 0.0 0.7 0.3 0.5 0.0 10.7 0.0 0.3 0.9 0.0 110.6 1.7 2.1 2.2 4.5 1.9 2.5 3.3 2.4 2.8 2.5 3.6 3.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 3.9 0.0 0.0 0.0 0.0 1.6 2.7 0.0 0.0 75.6 0.0 6.5 28.3 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.9;Inhibitory neurons: 111.4;Microglial cells: 52.5;Oligodendrocyte precursor cells: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 144.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: AB_2672381, HPA051273: AB_2681416, HPA059943: AB_2684173" "unprognostic (5.85e-3)" "unprognostic (4.38e-2)" "unprognostic (2.39e-1)" "unprognostic (3.28e-3)" "unprognostic (6.64e-2)" "unprognostic (3.92e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-4)" "unprognostic (2.67e-1)" "unprognostic (1.16e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (8.60e-2)" "unprognostic (5.39e-2)" "unprognostic (6.05e-2)" "unprognostic (2.78e-2)" 3.4 5.7 1.3 5.8 2.2 13.9 2.6 1.1 3.8 7.7 0.0 3.7 3.2 6.0 2.9 8.8 5.1 3.9 1.8 0.8 0.6 2.9 1.0 2.9 7.7 0.3 0.7 7.1 1.6 3.9 3.5 2.6 0.0 5.4 3.4 2.0 2.3 3.6 1.1 6.4 4.7 3.9 0.2 7.2 4.2 6.0 1.6 10.3 2.0 1.2 5.0 7.0 8.0 0.8 13.7 9.4 10.3 13.2 4.7 10.4 14.5 10.2 16.2 11.4 9.4 0.1 7.1 12.7 2.2 15.5 15.6 16.2 13.2 12.6 9.1 144.3 1.0 13.7 8.0 0.0 3.2 25.4 42.1 4.3 17.3 10.2 4.1 10.3 0.0 8.5 0.1 4.1 5.0 3.0 6.6 42.9 11.3 10.1 9.6 11.8 0.8 4.7 6.7 16.7 8.3 4.4 6.1 0.2 1.0 5.6 5.9 34.1 4.5 6.5 7.5 10.7 2.9 1.7 9.5 13.7 4.4 22.7 0.1 1.1 0.6 4.6 1.5 0.2 1.4 0.2 1.1 1.3 0.7 0.0 0.9 1.0 2.0 1.5 0.1 0.6 1.2 0.7 1.3 2.2 1.1 3.8 0.8 0.6 0.3 0.7 0.0 0.2 1.6 0.8 2.7 3.2 1.3 37.9 3.6 8.3 2.9 3.2 6.2 9.9 4.1 2.5 1.9 1.5 5.9 5.5 0.0 3.4 20.9 8.4 0.0 1.8 2.7 3.3 16.2 5.4 3.0 0.4 96.9 1.0 0.9 11.8 11.2 1.7 12.0 14.7 6.4 0.3 2.6 8.4 111.4 2.1 4.1 4.7 10.4 3.2 14.0 8.0 3.6 52.5 7.9 4.2 12.3 80.4 3.8 1.2 2.5 22.2 7.2 1.6 1.0 0.2 8.5 0.5 26.3 4.4 7.9 10.0 7.4 23.5 7.4 1.2 18.0 4.2 3.8 4.3 TRIM22 "GPSTAF50, RNF94, STAF50" ENSG00000132274 "Tripartite motif containing 22" Q8IYM9 11 5689697-5737089 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 135.9;dendritic cells: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 174.6;BJ hTERT+ SV40 Large T+ RasG12V: 209.9;HSkMC: 190.6;TIME: 153.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003307, HPA003575" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA003307: AB_1080381, HPA003575: AB_1080378" "unprognostic (1.47e-2)" "unprognostic (5.27e-3)" "unprognostic (4.00e-2)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.86e-3)" "unprognostic (2.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" "unprognostic (1.15e-1)" "unprognostic (9.16e-2)" 54.0 21.3 13.1 101.3 18.8 90.3 50.7 16.3 23.7 42.7 25.5 36.0 25.2 50.6 70.2 37.1 49.3 78.6 22.6 14.7 16.5 21.2 72.5 83.4 139.0 17.9 16.7 60.3 17.2 8.0 12.6 21.5 16.7 43.3 53.4 11.0 65.4 52.6 13.4 18.1 53.4 52.1 17.7 143.1 39.5 15.4 12.8 101.2 21.7 40.6 120.7 61.6 22.6 29.3 2.8 1.2 13.9 2.4 88.6 174.6 5.0 53.3 93.9 89.8 209.9 1.7 8.6 111.9 13.0 80.2 20.6 10.5 34.0 56.4 10.7 2.0 0.0 6.4 5.6 1.4 107.8 18.2 11.4 190.6 54.3 18.7 9.6 124.5 128.7 1.0 2.3 4.7 111.6 1.5 54.1 16.9 40.3 0.5 4.9 62.6 3.4 2.3 51.1 14.9 1.4 2.7 4.5 4.5 2.1 56.8 4.5 17.9 153.6 56.4 29.8 2.5 2.4 4.9 4.4 11.2 67.7 28.9 7.2 108.7 118.5 79.6 109.0 143.3 145.9 149.4 118.4 117.2 138.7 158.2 106.5 102.7 103.1 61.3 181.1 177.0 197.9 181.9 13.1 18.8 16.3 23.7 14.7 16.5 17.9 16.7 16.7 17.7 12.8 29.3 54.4 67.3 57.7 2.0 135.9 12.6 17.0 42.5 56.3 0.5 17.7 14.0 6.0 7.2 60.5 29.5 0.0 1.5 113.9 4.7 5.9 11.2 0.3 16.1 27.0 40.5 4.2 16.8 4.9 8.0 4.7 36.2 20.9 23.8 17.7 5.4 33.5 4.3 18.7 1.7 0.3 9.0 30.5 87.1 46.6 2.0 36.1 67.8 5.4 52.5 59.0 6.4 83.4 1.0 0.5 5.4 6.3 30.1 18.8 9.9 4.4 3.3 52.5 1.0 13.1 35.1 24.4 0.6 0.3 14.1 8.7 2.3 89.3 13.0 5.0 18.8 TRIM25 "EFP, RNF147, ZNF147" ENSG00000121060 "Tripartite motif containing 25" Q14258 17 56836387-56914080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Ligase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 23.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 23.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005909 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA005909: AB_1078722" "unprognostic (8.73e-3)" "unprognostic (1.57e-2)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (2.69e-1)" "unprognostic (3.78e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (1.53e-1)" "unprognostic (4.23e-1)" "unprognostic (1.15e-1)" "prognostic favorable (3.36e-4)" "unprognostic (3.23e-1)" "unprognostic (3.11e-2)" "prognostic favorable (9.35e-4)" "unprognostic (5.21e-2)" "unprognostic (5.13e-2)" "unprognostic (7.39e-2)" 16.3 20.7 9.8 19.8 10.4 47.7 13.1 9.5 23.2 14.5 11.1 19.7 19.4 12.1 8.5 20.4 18.2 9.7 11.1 9.0 11.3 11.9 29.8 25.0 17.3 10.3 9.9 14.3 16.7 13.0 10.3 9.5 10.3 9.3 17.3 11.8 15.3 7.4 12.6 29.2 20.2 12.4 11.4 41.6 17.0 9.1 12.1 18.5 10.8 7.6 19.7 12.1 14.6 9.0 77.2 37.4 9.0 30.7 66.6 55.8 0.1 29.6 59.6 69.4 59.3 36.7 41.1 74.6 59.8 28.6 75.4 44.5 44.5 39.9 38.5 64.1 35.0 48.1 29.0 41.0 57.0 58.2 33.2 25.1 65.7 36.2 76.4 32.9 46.7 50.2 12.0 43.8 35.8 51.3 65.6 41.9 5.8 63.3 71.5 46.3 30.2 47.4 40.5 59.7 17.5 16.3 23.3 37.1 69.7 5.8 50.3 46.8 31.3 32.2 23.1 50.1 31.2 24.7 51.1 12.1 31.2 39.4 13.0 4.8 3.0 1.2 1.0 2.5 1.3 2.2 0.9 1.0 3.1 1.7 0.7 1.0 23.5 1.1 1.8 2.2 2.0 1.1 9.8 10.4 9.5 23.2 9.0 11.3 10.3 9.9 10.3 11.4 12.1 9.0 27.3 35.3 19.8 7.5 12.7 18.5 8.5 10.5 13.1 9.9 12.6 11.9 7.5 20.0 16.6 9.2 29.2 5.4 15.1 54.8 0.0 19.1 3.5 44.9 20.0 32.7 18.6 11.1 4.1 21.6 10.7 16.0 32.6 72.5 3.8 23.0 32.2 30.9 14.8 3.3 8.2 28.7 6.1 27.5 24.6 2.1 9.6 29.3 14.2 8.4 28.3 5.7 11.3 12.1 0.3 32.2 54.2 9.4 17.7 21.6 20.0 8.0 18.5 22.2 6.6 13.1 9.2 0.4 0.3 24.5 30.5 15.9 11.5 45.3 25.7 25.4 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991231 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favorable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favorable (8.20e-5)" "prognostic favorable (4.94e-9)" 7.1 6.0 1.8 10.8 1.8 13.0 6.1 1.6 2.4 7.3 3.4 5.8 6.6 7.3 9.6 7.8 7.4 6.6 3.7 1.7 1.9 9.9 5.6 9.3 13.6 3.0 2.1 4.6 3.2 2.9 2.0 6.3 2.7 7.0 7.3 0.4 6.1 6.2 7.6 5.2 8.9 6.1 2.4 14.3 5.8 2.1 2.7 7.7 5.5 3.0 14.6 7.0 7.0 2.7 4.8 2.6 0.4 5.6 13.0 17.3 4.6 5.9 11.7 11.2 18.5 2.0 5.0 10.5 9.4 7.3 10.8 7.3 3.6 5.8 6.6 10.7 2.3 4.8 4.6 2.0 17.2 5.7 9.4 17.4 4.2 6.9 2.5 9.2 9.8 5.0 3.2 5.7 13.5 2.3 5.5 6.4 1.8 0.0 3.5 8.3 5.4 11.2 13.3 9.3 0.1 0.1 4.4 9.1 16.2 0.6 1.3 7.3 10.1 2.0 3.4 3.5 4.0 6.5 5.1 11.7 5.4 6.9 12.6 12.1 10.2 4.7 6.9 12.5 6.6 13.1 5.8 6.2 9.8 15.1 5.4 6.0 11.4 6.5 11.7 9.0 7.9 7.1 1.8 1.8 1.6 2.4 1.7 1.9 3.0 2.1 2.7 2.4 2.7 2.7 37.6 25.6 47.1 0.3 120.2 14.9 56.9 16.1 24.5 0.6 20.1 12.8 6.0 18.6 32.4 46.0 0.0 23.5 88.5 48.3 17.6 28.5 1.1 48.4 28.1 39.9 18.1 10.3 0.1 14.9 23.5 25.5 24.5 69.4 35.5 52.4 35.0 17.5 32.6 0.0 0.1 33.3 16.2 94.0 32.7 2.8 19.9 81.3 10.6 34.7 113.2 0.2 107.1 0.0 0.2 20.4 47.4 18.8 34.3 39.7 48.3 69.5 22.7 1.1 6.6 23.1 28.2 0.3 0.5 42.7 9.2 21.2 53.1 23.0 25.6 94.7 TRIM60 "FLJ35882, RNF129, RNF33" ENSG00000176979 "Tripartite motif containing 60" Q495X7 4 165016458-165041749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 1.5;testis: 1.5" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 5.1;Early spermatids: 3.0;Extravillous trophoblasts: 10.6;Spermatocytes: 9.6;Spermatogonia: 8.2;Syncytiotrophoblasts: 5.6" "Cancer enriched" "Detected in single" 103 "testis cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BEWO: 14.2" "Not detected" "Not detected" "HPA035809, HPA035810, HPA061496" Uncertain Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA035809: AB_2674794, HPA035810: AB_10601827, HPA061496: AB_2684540" "unprognostic (1.10e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 0.2 0.3 0.2 0.3 0.0 0.4 0.5 0.9 0.7 0.0 0.1 0.0 0.0 5.1 0.6 0.0 0.0 0.0 3.0 0.8 0.9 0.7 0.0 0.0 0.2 0.0 10.6 0.3 0.0 1.5 0.0 0.2 0.0 1.1 0.5 0.0 0.3 0.0 0.0 1.3 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.4 0.7 0.3 0.0 0.1 0.8 0.5 0.0 0.0 0.3 9.6 8.2 0.0 0.3 5.6 0.7 0.2 0.0 0.1 TRIM65 ENSG00000141569 "Tripartite motif containing 65" Q6PJ69 17 75880335-75896951 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021575, HPA021578, HPA064820" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA021575: AB_1858314, HPA021578: AB_1858315, HPA064820: AB_2685359" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-1)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (4.74e-6)" "unprognostic (5.36e-2)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (5.82e-2)" "unprognostic (6.00e-3)" "prognostic unfavorable (1.82e-5)" "unprognostic (2.86e-3)" "unprognostic (7.18e-2)" "unprognostic (4.24e-3)" "unprognostic (7.50e-3)" 13.0 7.8 12.5 8.5 15.2 7.4 10.7 15.3 13.5 15.5 11.0 14.1 8.8 14.7 6.8 14.2 13.1 7.1 10.3 11.5 13.2 11.2 8.4 12.9 10.5 15.0 14.6 14.1 15.7 7.4 11.8 5.4 14.8 11.7 7.9 7.2 12.6 8.1 13.2 14.6 13.5 8.3 13.8 16.6 11.3 3.9 14.5 6.5 12.2 6.9 8.2 14.6 14.0 17.0 19.8 20.2 7.8 22.2 13.5 19.2 4.0 8.3 8.9 11.1 9.4 9.1 17.0 21.4 6.5 7.2 15.6 13.7 16.8 18.6 6.8 11.1 28.9 16.9 20.4 12.5 13.4 17.2 18.9 12.0 14.4 8.9 16.0 9.3 29.2 27.2 29.3 19.5 8.7 20.6 38.0 33.7 17.7 20.0 19.5 31.3 11.2 30.9 11.2 8.2 16.1 14.9 11.4 21.3 22.7 9.7 21.2 24.2 14.5 26.6 13.5 13.3 16.9 17.9 7.4 6.2 16.2 32.2 11.8 1.4 1.1 1.8 1.9 1.0 2.2 1.4 1.4 1.9 0.9 2.0 1.5 1.5 1.1 1.9 0.6 1.3 1.3 0.6 12.5 15.2 15.3 13.5 11.5 13.2 15.0 14.6 14.8 13.8 14.5 17.0 8.4 6.4 4.8 13.1 7.5 2.9 5.7 2.4 3.4 19.0 3.7 3.0 4.3 5.7 3.4 9.2 12.5 0.9 9.0 3.6 1.9 3.2 0.4 2.8 9.2 8.2 0.0 9.5 4.5 3.4 3.6 6.6 7.1 4.0 7.0 8.6 5.7 3.8 8.9 5.0 5.9 6.6 6.1 5.4 9.3 0.5 13.7 6.9 8.8 3.7 4.9 6.3 3.1 6.6 9.3 5.3 2.9 9.4 5.8 5.1 4.8 5.9 1.8 12.9 0.0 9.3 5.2 0.8 2.9 6.7 3.7 0.5 8.5 6.4 5.9 2.8 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 193.3;tongue: 51.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.8;Cardiomyocytes: 40.1;Squamous epithelial cells: 39.6;Suprabasal keratinocytes: 28.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 16.4;HDLM-2: 35.0;PC-3: 18.8;TIME: 16.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 2.1 1.5 1.2 0.4 1.0 0.4 2.1 10.5 3.0 5.5 0.4 1.9 0.3 1.3 3.1 27.0 2.2 0.2 8.5 0.9 1.7 3.9 0.6 2.6 0.4 3.1 2.9 1.5 4.8 2.7 5.5 0.3 2.8 2.8 0.5 1.6 7.3 0.6 193.3 28.7 1.3 0.6 1.3 1.4 2.2 1.3 2.0 0.4 6.3 51.0 2.1 2.2 9.5 1.3 9.0 4.4 0.1 0.5 0.7 0.8 0.2 1.9 0.0 0.7 1.8 0.4 12.0 0.6 6.1 2.6 3.7 16.4 4.8 13.8 0.2 35.0 1.8 0.9 12.2 0.2 2.2 0.0 2.0 0.1 10.5 0.4 6.7 2.7 3.9 1.6 0.5 2.0 0.4 1.3 0.5 0.3 0.0 14.5 18.8 0.4 6.0 1.4 4.9 0.0 0.4 1.1 4.2 0.2 6.5 0.2 1.0 0.4 16.0 0.2 3.4 0.6 6.3 2.8 0.4 1.0 0.5 0.7 1.5 0.0 1.7 0.0 0.4 0.7 0.7 0.1 0.4 0.4 0.3 0.2 0.7 0.5 0.0 0.1 0.5 0.2 0.9 0.3 1.2 1.0 10.5 3.0 0.9 1.7 3.1 2.9 2.8 1.3 2.0 1.3 7.3 0.0 1.1 0.0 1.0 17.8 4.3 11.1 12.0 6.2 0.8 1.5 40.1 0.0 6.3 3.7 0.0 0.1 0.8 5.9 5.9 0.7 0.9 0.2 0.3 4.6 0.0 0.0 1.3 2.4 0.7 4.8 11.2 0.7 0.0 0.1 5.7 0.4 1.1 0.0 3.9 3.3 2.0 6.0 2.8 0.0 0.9 2.9 1.8 0.0 5.7 0.6 1.0 2.0 0.1 5.0 6.5 1.5 0.1 2.5 0.0 1.5 2.9 2.9 13.1 17.3 5.8 1.5 0.4 39.6 28.4 0.0 1.4 0.1 3.4 5.3 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRIM8 "GERP, RNF27" ENSG00000171206 "Tripartite motif containing 8" Q9BZR9 10 102644479-102658318 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023560, HPA023561" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA023560: AB_10600414, HPA023561: AB_10601861" "unprognostic (4.32e-2)" "unprognostic (6.90e-2)" "unprognostic (3.02e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-1)" "unprognostic (5.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.03e-1)" "unprognostic (2.15e-3)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (1.52e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (8.34e-2)" "unprognostic (1.36e-2)" 80.1 47.6 67.2 21.5 68.1 26.0 58.4 62.9 55.0 63.0 35.8 50.9 17.8 53.5 9.3 42.0 55.6 22.0 67.8 55.0 56.5 77.9 62.2 70.3 18.3 72.4 72.7 45.2 80.4 36.6 43.5 21.3 64.7 55.5 9.5 18.1 69.1 21.9 80.8 48.3 43.8 17.1 60.4 42.8 61.9 20.1 84.4 18.7 67.4 38.8 11.8 62.9 49.9 54.2 96.4 18.7 16.3 28.7 17.2 40.6 21.1 34.4 59.3 32.1 24.6 30.7 93.0 30.7 102.9 57.5 11.4 32.7 12.2 40.4 21.3 34.4 23.4 78.3 12.9 67.4 55.8 15.5 28.3 47.0 21.9 64.8 32.9 83.4 40.6 13.6 17.3 33.4 24.3 45.5 27.8 57.7 12.7 25.6 38.0 18.6 49.2 16.6 37.4 48.0 12.3 26.2 18.8 17.2 42.6 16.9 58.4 28.2 94.8 40.9 22.4 23.3 68.8 49.0 28.5 16.3 65.5 39.2 9.7 14.0 5.2 2.7 6.8 4.6 6.5 8.9 7.3 5.4 4.5 7.4 6.4 5.7 17.9 6.0 5.7 12.4 7.5 4.5 67.2 68.1 62.9 55.0 55.0 56.5 72.4 72.7 64.7 60.4 84.4 54.2 46.0 57.7 71.2 33.6 29.5 31.5 12.6 21.2 21.6 33.4 53.9 45.3 38.0 38.6 33.6 88.3 8.4 13.0 52.8 15.4 41.1 63.2 1.1 91.5 61.7 30.1 21.6 2.5 8.9 44.9 2.6 38.9 20.4 81.6 8.8 32.2 31.8 33.3 25.4 28.6 13.6 32.8 18.3 40.5 24.1 1.7 31.1 43.5 17.8 13.1 58.1 26.1 24.7 18.1 17.6 65.0 16.4 34.3 18.6 30.5 32.0 53.0 38.5 15.1 13.1 35.7 38.4 2.4 5.1 19.8 22.9 10.9 26.6 38.9 21.4 30.1 TRIP6 "MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1" ENSG00000087077 "Thyroid hormone receptor interactor 6" Q15654 7 100867387-100873454 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046454, CAB046460, HPA052813" Approved Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 21000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "CAB046454: AB_10604048, CAB046460: AB_2303907, HPA052813: AB_2681961" "unprognostic (7.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.84e-3)" "unprognostic (3.52e-2)" "unprognostic (2.92e-2)" "unprognostic (3.18e-2)" "unprognostic (4.61e-3)" "unprognostic (8.48e-2)" "unprognostic (4.18e-2)" "unprognostic (5.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.25e-2)" "unprognostic (5.07e-2)" "unprognostic (9.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" 42.2 43.0 34.3 15.7 39.5 15.7 42.6 36.2 41.6 59.4 40.4 45.2 9.7 74.6 16.2 63.7 49.5 37.0 39.1 32.6 36.2 55.8 41.1 33.8 14.6 40.6 36.9 50.6 39.8 46.4 16.8 27.4 35.9 42.9 8.4 5.4 46.8 56.7 10.2 55.1 21.5 27.5 36.9 20.0 27.6 18.4 38.4 16.6 50.5 5.8 12.1 47.2 52.5 37.0 128.1 63.4 26.8 126.1 37.8 44.9 131.2 82.3 79.8 101.2 94.8 55.8 143.9 5.5 81.3 87.7 128.3 94.2 38.0 149.2 27.3 19.1 58.5 0.5 117.9 0.8 99.3 66.5 7.1 81.1 94.0 67.8 108.2 64.2 52.8 19.1 83.3 1.0 90.5 286.9 1.3 99.5 92.4 52.3 50.4 47.9 27.0 12.7 65.5 42.8 9.7 1.7 67.5 192.3 78.1 43.8 20.3 77.5 86.5 149.5 145.8 167.5 186.7 1.0 2.1 0.8 92.9 7.8 230.5 0.0 1.2 0.2 0.1 2.1 0.4 2.5 0.9 0.7 1.9 2.4 1.1 0.6 0.0 0.0 3.8 5.2 0.9 0.4 34.3 39.5 36.2 41.6 32.6 36.2 40.6 36.9 35.9 36.9 38.4 37.0 24.5 48.1 38.8 14.4 8.0 131.9 151.5 144.1 78.0 0.9 48.3 55.8 13.9 38.6 87.0 60.7 0.0 113.0 12.0 9.5 80.3 106.9 1.1 22.7 46.1 26.3 4.9 6.7 0.3 84.3 90.4 54.6 40.8 44.8 8.2 55.3 23.9 28.8 44.0 1.7 0.4 12.8 34.6 8.0 59.3 2.8 65.9 17.5 37.4 5.6 20.3 94.8 0.0 4.0 6.5 95.0 13.1 72.6 16.0 72.9 3.6 130.0 34.3 4.6 72.3 50.9 104.0 4.7 4.5 68.2 98.3 132.8 7.1 58.3 18.8 155.6 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavorable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 22.0 19.8 16.5 16.2 15.3 21.1 21.0 14.7 22.1 24.3 14.8 20.0 11.8 22.9 6.3 22.3 23.6 8.9 17.3 15.5 14.7 18.0 22.1 17.3 23.2 16.0 14.8 28.7 25.4 10.0 17.2 11.3 16.8 23.0 10.9 6.5 17.0 11.4 28.8 23.4 21.7 12.5 14.2 30.6 18.9 16.8 16.2 11.6 19.2 10.5 15.9 22.3 22.2 17.6 38.6 25.3 26.9 46.0 26.7 34.1 38.7 42.1 20.9 45.3 39.1 27.4 30.8 47.7 53.6 22.9 23.7 34.8 45.2 37.3 20.9 31.3 62.8 38.0 68.7 46.5 48.7 77.2 43.1 48.4 48.4 47.3 44.1 28.9 33.8 35.2 83.7 14.9 28.6 42.6 31.7 83.3 64.0 24.2 57.5 52.5 34.6 65.8 28.3 38.2 63.5 28.9 26.2 53.7 44.8 19.4 21.0 42.8 38.2 65.1 25.5 39.8 75.1 25.6 53.4 44.1 30.3 80.7 34.7 1.8 18.9 0.6 8.9 15.0 8.6 12.4 9.6 8.6 18.2 12.9 11.1 8.5 3.7 5.6 9.9 10.6 6.9 10.7 16.5 15.3 14.7 22.1 15.5 14.7 16.0 14.8 16.8 14.2 16.2 17.6 15.5 12.8 13.1 8.5 47.5 24.0 27.0 16.8 22.8 8.9 16.6 20.2 8.3 11.5 9.6 12.9 2.1 21.7 19.6 16.6 5.9 17.3 22.4 7.9 11.7 17.6 7.2 13.0 12.0 14.9 22.6 14.3 17.9 9.8 29.8 19.7 6.1 10.8 47.7 8.4 9.1 14.1 4.1 80.0 51.0 47.9 14.0 57.4 17.8 10.3 64.8 6.1 12.3 2.5 7.5 12.8 6.8 12.8 24.2 29.0 7.8 14.2 9.2 12.6 13.1 17.5 16.1 21.1 20.0 20.7 20.6 15.5 24.4 14.6 22.5 20.3 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 99.5;Spermatogonia: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: AB_2680099, HPA058241: AB_2683651" "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.68e-2)" 4.3 3.7 2.0 3.1 2.6 2.2 4.4 2.6 2.9 1.9 1.5 3.6 4.3 2.7 3.9 3.6 5.8 3.4 2.3 1.8 2.5 4.9 9.8 2.4 4.4 2.6 2.5 3.3 5.9 3.7 2.3 3.7 2.9 4.1 3.6 2.8 3.9 2.2 3.9 3.7 4.5 2.7 2.7 3.5 4.4 9.9 2.4 4.3 6.1 2.7 4.4 2.9 2.0 4.3 8.2 5.4 10.1 5.7 6.0 8.4 7.8 9.6 3.7 5.8 4.1 4.9 9.4 10.9 3.7 5.6 5.9 4.4 10.9 5.1 8.6 13.7 5.4 8.0 4.4 7.6 5.5 19.6 7.8 5.4 14.4 5.7 14.0 3.0 6.4 10.0 17.5 9.4 4.5 9.4 16.4 3.5 6.5 13.8 5.0 9.5 10.2 7.2 8.5 6.8 6.3 5.8 5.3 28.3 9.9 8.5 9.3 7.8 4.9 6.9 7.2 5.5 11.1 7.0 12.4 10.0 4.9 10.9 4.7 2.7 3.9 2.1 1.8 3.8 1.7 3.5 3.3 3.3 5.2 5.8 3.5 3.2 4.9 3.3 3.4 3.0 3.9 1.9 2.0 2.6 2.6 2.9 1.8 2.5 2.6 2.5 2.9 2.7 2.4 4.3 7.2 3.2 10.3 8.8 8.7 8.2 5.6 8.4 10.2 4.3 12.1 8.6 6.4 11.5 6.6 11.0 4.2 16.8 6.1 10.6 43.0 13.8 46.8 33.5 12.1 7.2 7.2 2.1 5.3 19.3 16.4 6.9 8.6 21.6 8.2 11.0 8.2 32.6 8.5 5.0 4.6 11.1 12.2 8.1 4.1 17.0 6.5 5.0 5.4 1.9 8.4 8.7 5.2 3.5 19.7 14.1 11.0 7.5 10.4 4.8 19.0 31.9 20.6 5.9 13.1 5.7 8.1 99.5 55.0 10.2 9.5 17.5 5.5 8.1 10.6 6.6 TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150498 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: AB_10601254" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (5.76e-2)" "unprognostic (2.37e-1)" "unprognostic (9.17e-3)" "unprognostic (4.97e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.16e-3)" "unprognostic (3.28e-2)" "unprognostic (8.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (6.89e-6)" "unprognostic (3.12e-2)" "unprognostic (7.71e-2)" "unprognostic (1.99e-2)" "unprognostic (1.70e-3)" 8.8 8.7 6.9 12.2 9.8 5.2 14.5 9.6 9.6 11.2 6.7 9.3 11.2 13.9 11.8 8.5 9.2 7.2 8.0 6.5 9.7 8.8 8.7 7.8 18.2 8.5 9.0 13.5 11.5 12.9 6.8 10.7 8.7 10.4 11.3 21.7 9.1 8.1 13.1 14.7 10.7 10.1 7.0 14.1 10.0 9.4 8.5 11.3 12.0 6.2 14.6 9.5 10.3 14.9 17.5 10.0 16.5 11.5 8.7 16.9 18.0 18.0 7.1 13.4 11.1 11.9 7.0 28.7 21.8 14.4 8.9 15.4 30.6 14.0 23.1 29.0 24.2 17.2 23.1 11.6 15.7 30.0 15.4 11.9 15.5 25.5 33.3 8.4 12.4 21.0 36.6 17.9 13.6 6.7 24.6 15.6 23.0 16.7 19.9 26.0 25.0 15.7 11.1 13.6 10.7 17.9 16.6 15.8 21.6 16.1 9.3 26.1 13.0 17.8 11.9 15.1 24.3 22.8 20.0 34.0 20.1 23.5 7.0 0.2 5.8 3.1 10.5 6.1 13.0 19.9 11.3 10.6 7.0 18.7 16.8 14.0 2.5 7.9 5.1 12.8 8.6 5.6 6.9 9.8 9.6 9.6 6.5 9.7 8.5 9.0 8.7 7.0 8.5 14.9 13.1 25.6 17.0 34.0 29.0 9.7 14.2 14.2 19.9 38.9 10.7 7.9 11.1 12.8 22.2 14.7 29.2 14.2 18.9 8.0 13.7 10.5 20.9 14.3 21.0 15.7 20.4 11.3 23.1 6.1 10.2 13.7 11.7 8.0 21.5 18.7 17.9 11.4 7.6 28.6 32.1 9.9 18.3 10.1 7.0 6.0 24.8 10.3 10.6 25.3 14.7 16.6 41.2 33.7 97.4 8.5 9.6 18.4 9.0 12.6 13.0 10.7 20.4 44.7 19.7 16.0 13.4 47.6 21.9 12.2 11.9 7.3 21.5 15.8 13.6 10.0 TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 9.4;Excitatory neurons: 14.6;Granulosa cells: 12.3;Inhibitory neurons: 20.0;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 9.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 37.1;SH-SY5Y: 33.8;SuSa: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071449 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA071449: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" 3.9 3.0 13.9 1.3 10.6 1.0 3.7 0.8 23.7 9.5 0.9 3.2 0.9 13.4 6.6 1.6 5.3 4.2 2.4 9.3 17.2 3.9 16.8 2.1 1.6 6.2 5.1 17.5 7.1 5.3 24.4 4.3 6.9 5.5 2.1 6.2 1.5 5.2 31.1 1.2 1.6 8.6 3.4 1.0 2.0 2.6 12.6 4.7 10.1 1.0 1.6 2.5 5.5 13.3 0.0 0.3 37.1 0.1 7.1 9.8 0.0 2.1 13.1 2.0 0.7 0.0 0.0 0.0 5.3 13.8 3.1 0.2 0.3 0.6 1.0 0.1 23.3 18.0 0.0 1.5 2.7 0.0 0.1 22.8 0.0 12.0 0.0 11.8 0.9 9.1 0.0 0.2 14.0 0.0 0.3 0.1 19.6 0.1 0.0 11.3 16.4 0.1 3.5 0.3 25.3 33.8 0.0 0.5 3.1 74.2 0.0 2.2 0.0 15.7 15.9 0.2 2.2 5.8 0.9 0.0 2.3 0.0 13.8 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.2 0.1 0.9 0.0 0.1 13.9 10.6 0.8 23.7 9.3 17.2 6.2 5.1 6.9 3.4 12.6 13.3 0.4 0.0 0.0 9.4 0.3 0.4 1.4 0.8 5.2 4.2 0.5 1.9 1.8 0.0 1.9 3.7 0.0 0.8 0.2 0.0 0.0 1.7 0.4 0.3 7.9 1.9 0.0 0.0 14.6 0.2 0.6 7.0 0.5 0.5 1.3 12.3 0.4 0.0 0.5 8.4 20.0 0.0 0.0 0.0 0.4 0.6 5.9 0.2 0.0 1.0 0.1 2.2 0.0 17.1 9.4 0.2 0.0 3.8 0.1 0.4 0.0 0.4 0.0 0.9 0.0 1.5 3.3 1.2 1.9 0.1 0.1 0.7 0.7 2.9 0.0 0.3 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 108.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 122.2;Oligodendrocytes: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 11.5 9.6 4.3 13.3 6.5 21.4 13.6 15.4 6.7 10.3 29.3 13.8 14.4 12.7 14.6 8.6 9.4 11.1 15.5 4.8 3.5 22.9 25.3 11.6 16.6 4.9 3.9 16.4 12.2 108.9 5.3 13.3 5.9 10.9 14.4 10.5 10.9 10.6 7.8 16.6 13.1 11.4 3.2 12.2 13.6 9.9 6.4 15.5 17.3 9.1 14.4 11.4 8.1 10.4 21.4 21.0 17.2 19.1 48.5 36.2 20.9 26.4 36.7 16.5 21.6 29.1 11.6 46.4 12.7 30.8 42.5 35.1 23.3 19.5 23.4 26.0 13.7 37.1 31.5 15.4 44.0 38.8 27.6 33.9 22.4 18.8 35.0 24.0 13.5 28.8 42.6 34.5 30.4 33.7 25.1 18.8 13.0 29.4 12.8 27.2 23.7 22.7 23.0 49.9 14.2 18.1 18.2 28.7 35.8 30.1 18.0 41.6 20.7 26.1 12.4 122.4 30.8 23.3 54.9 44.0 28.4 77.5 24.8 1.8 1.3 1.6 2.5 1.3 2.9 2.2 1.8 1.7 1.5 2.3 1.6 1.9 1.7 2.4 1.4 1.9 2.0 0.8 4.3 6.5 15.4 6.7 4.8 3.5 4.9 3.9 5.9 3.2 6.4 10.4 23.9 19.2 31.3 73.1 36.4 31.6 17.2 11.0 44.9 21.9 18.8 11.9 25.9 21.5 8.2 12.9 12.5 23.0 38.4 17.0 3.9 11.7 33.3 21.6 27.1 19.7 18.5 29.6 122.2 12.7 9.4 26.1 37.8 23.1 17.7 26.0 14.6 43.9 14.6 21.9 92.7 19.5 6.1 22.4 19.8 26.0 26.4 26.5 19.6 66.5 24.2 8.5 29.9 80.9 109.1 15.5 13.9 20.3 33.2 24.9 23.4 11.0 19.3 22.6 13.1 30.0 22.0 23.1 23.6 25.7 24.2 16.3 34.5 22.2 20.4 11.1 TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.2;skin 1: 4.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.7;Plasma cells: 15.9;Proximal enterocytes: 26.1;Suprabasal keratinocytes: 24.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.3;BEWO: 5.0;CACO-2: 3.1;RH-30: 11.9;T-47d: 5.2;U-266/70: 3.1;U-266/84: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" 0.1 0.0 1.1 0.5 1.1 0.5 0.2 0.1 1.1 0.3 0.0 0.9 2.0 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.2 0.0 0.1 0.3 0.2 0.4 0.1 1.7 0.2 0.1 0.0 1.5 4.8 5.2 0.1 0.1 0.2 0.9 0.4 0.9 0.0 0.0 0.5 0.5 0.2 0.3 1.8 3.3 0.0 0.3 0.0 0.2 0.3 5.0 0.1 0.0 0.0 0.0 3.1 0.8 0.1 1.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.2 0.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 11.9 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 3.1 2.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 1.1 0.1 1.1 0.6 0.3 0.4 0.3 0.4 0.1 0.9 1.8 0.2 0.0 2.5 2.9 5.8 18.7 3.9 0.2 10.2 1.2 0.9 0.5 3.5 1.5 0.2 0.0 0.0 0.3 2.6 8.9 1.9 0.0 0.3 0.7 0.9 1.6 0.0 0.0 1.6 0.0 0.9 3.7 6.1 0.9 0.0 1.1 0.0 0.3 0.3 5.0 0.6 2.7 0.0 0.0 3.8 0.4 3.1 0.8 7.2 0.0 0.1 2.2 3.1 0.5 2.3 1.2 2.5 3.4 15.9 5.9 26.1 2.3 0.2 1.0 0.0 6.9 1.8 0.0 1.5 2.9 24.6 0.5 1.8 2.8 0.9 3.7 TSC22D3 "DIP, DSIPI, GILZ, hDIP, TSC-22R" ENSG00000157514 "TSC22 domain family member 3" Q99576 X 107713221-107777342 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1234.8;dendritic cells: 1146.4;Plasma cells: 2348.5;T-cells: 1479.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 380.5;ASC TERT1: 259.7;HHSteC: 628.0;hTCEpi: 572.7;Karpas-707: 364.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001916, CAB034364" Approved Approved "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Nuclear speckles, Golgi apparatus" "CAB034364: AB_2272198, HPA001916: AB_2666504" "unprognostic (3.67e-2)" "unprognostic (3.90e-3)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.49e-2)" "unprognostic (3.21e-2)" "unprognostic (3.73e-3)" "unprognostic (4.40e-2)" "unprognostic (9.42e-2)" "unprognostic (5.32e-2)" "unprognostic (3.25e-1)" "unprognostic (7.47e-2)" "unprognostic (6.38e-2)" "unprognostic (1.37e-3)" "unprognostic (6.41e-2)" "unprognostic (4.14e-1)" "unprognostic (9.64e-2)" 536.4 240.5 90.3 394.8 93.5 433.3 447.3 101.0 105.0 396.4 104.1 290.2 87.2 269.3 72.0 300.4 369.8 167.1 331.9 81.3 102.9 194.9 177.4 522.6 281.0 99.6 97.2 371.1 113.8 55.7 136.2 163.8 98.9 404.4 183.6 22.5 333.4 160.5 729.3 493.6 426.3 178.7 92.8 408.2 390.4 43.8 99.3 203.2 313.0 187.8 338.2 508.2 486.9 91.3 10.9 18.2 9.3 25.7 380.5 259.7 3.7 16.9 14.1 7.8 8.6 0.1 35.8 23.4 40.1 13.7 5.5 53.5 19.1 54.2 3.3 7.0 9.0 11.5 76.9 1.0 628.0 2.5 37.7 238.8 572.7 6.1 158.7 78.8 29.3 2.5 3.6 364.1 67.2 37.8 0.7 40.5 16.3 11.5 11.7 1.2 23.5 51.3 26.1 7.3 2.4 20.3 16.6 89.2 128.8 16.9 17.0 52.4 44.1 23.6 7.1 4.8 3.4 79.6 37.8 11.2 12.0 46.7 6.7 668.9 417.2 1653.1 649.7 524.1 484.2 584.0 740.6 641.5 399.5 559.6 686.3 643.0 2396.6 968.4 851.8 81.4 1080.9 1624.1 90.3 93.5 101.0 105.0 81.3 102.9 99.6 97.2 98.9 92.8 99.3 91.3 423.5 64.1 164.7 10.4 1234.8 110.0 82.8 129.7 435.4 52.0 97.0 47.5 31.8 70.1 106.9 47.8 0.0 3.2 1146.4 26.2 232.8 28.3 28.8 24.2 40.9 171.7 64.2 481.5 13.1 22.2 140.5 454.2 200.3 29.7 353.2 15.3 247.0 95.6 121.3 62.2 12.9 32.9 83.4 396.3 191.8 41.2 230.5 539.1 437.6 16.9 126.0 8.9 234.8 37.7 23.7 22.7 19.6 319.7 2348.5 106.5 58.6 48.6 61.0 19.1 433.9 245.4 248.3 24.1 15.3 182.6 79.1 9.9 1479.6 89.6 33.0 42.2 TSEN2 "MGC2776, SEN2, SEN2L" ENSG00000154743 "TRNA splicing endonuclease subunit 2" Q8NCE0 3 12484421-12541549 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 43.8;Excitatory neurons: 42.8;Inhibitory neurons: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027120, HPA027125, HPA027268" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA027120: AB_10600197, HPA027125: AB_10601896, HPA027268: AB_10601347" "unprognostic (5.58e-2)" "unprognostic (4.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.71e-2)" "unprognostic (9.59e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (1.42e-1)" "unprognostic (5.66e-2)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "unprognostic (6.15e-2)" "unprognostic (1.41e-2)" "unprognostic (6.99e-2)" "unprognostic (4.90e-2)" "unprognostic (6.06e-2)" "prognostic favorable (3.49e-4)" 8.9 9.4 3.4 1.1 3.9 0.3 8.9 4.4 4.8 11.5 3.7 11.5 1.4 10.9 2.6 8.6 12.0 1.8 15.5 3.5 3.7 10.2 8.5 6.0 2.2 3.6 3.5 14.2 12.1 3.2 10.9 0.9 3.6 10.0 2.3 3.4 6.7 3.2 15.9 8.3 6.9 3.2 3.3 6.6 9.7 6.7 3.9 2.6 9.0 3.8 2.2 11.5 9.7 3.8 6.2 11.8 5.5 7.4 6.3 7.7 7.6 5.8 4.3 6.6 5.1 4.2 5.2 5.5 3.3 4.0 5.8 5.8 7.8 9.4 5.4 5.5 9.8 5.1 9.1 5.7 5.4 9.3 2.1 4.9 11.2 10.1 9.7 3.3 4.7 8.8 10.7 3.4 6.5 11.9 9.6 6.1 6.5 10.5 13.5 4.6 2.3 13.5 9.9 4.8 1.5 4.5 6.7 5.0 4.8 3.1 10.1 5.1 4.5 4.2 3.9 4.7 9.7 3.1 8.6 6.2 5.6 11.8 5.4 0.6 1.9 0.0 2.7 1.6 4.4 3.7 4.6 3.8 2.3 3.2 6.2 5.1 0.4 2.5 1.7 3.4 1.6 2.6 3.4 3.9 4.4 4.8 3.5 3.7 3.6 3.5 3.6 3.3 3.9 3.8 5.5 3.2 3.3 26.1 8.9 2.9 11.2 5.6 13.1 28.1 3.7 4.3 7.0 10.0 3.8 11.0 43.8 8.8 2.6 9.2 1.9 6.2 1.6 7.1 7.4 6.2 4.2 8.4 42.8 4.2 4.3 5.7 13.7 3.7 5.1 17.7 3.6 5.0 4.6 10.1 46.4 5.2 4.1 3.5 1.7 2.8 9.0 3.6 3.6 16.9 2.4 8.0 6.2 19.1 31.8 4.5 5.0 10.1 3.8 6.2 2.3 6.9 11.1 34.1 6.6 7.9 6.3 14.0 23.0 7.1 4.8 1.9 4.6 15.3 8.4 8.0 TSG101 "TSG10, VPS23" ENSG00000074319 "Tumor susceptibility 101" Q99816 11 18468336-18526951 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004283, HPA006161" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoli, Plasma membrane" "CAB004283: AB_671392, HPA006161: AB_1080408" "unprognostic (1.42e-1)" "unprognostic (7.91e-2)" "unprognostic (2.11e-1)" "unprognostic (6.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.72e-3)" "prognostic unfavorable (3.74e-6)" "unprognostic (5.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-2)" "unprognostic (4.15e-3)" "unprognostic (4.27e-2)" "prognostic favorable (5.52e-6)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" 40.4 55.6 41.1 32.2 42.2 60.8 56.6 43.1 50.8 44.8 45.7 49.5 42.8 40.2 56.3 56.7 49.3 36.5 68.2 42.1 44.5 70.1 62.3 43.9 42.9 42.4 42.3 44.6 45.4 61.5 36.5 61.4 42.4 43.1 59.0 43.6 46.4 41.1 77.1 47.2 43.4 42.9 43.9 34.0 45.4 55.5 41.8 45.9 52.4 83.0 57.4 46.9 42.2 46.5 51.3 79.1 73.7 51.1 82.2 85.4 63.7 77.1 103.0 92.2 90.3 54.3 27.5 65.5 49.2 86.4 103.7 77.0 74.0 70.3 102.0 95.4 87.7 41.1 38.6 79.7 106.3 64.6 69.8 75.0 139.9 48.6 131.6 102.2 76.8 68.4 66.9 55.2 112.7 85.7 45.7 66.8 45.1 115.6 81.5 37.0 72.5 54.7 63.6 68.8 52.2 88.6 75.7 61.6 101.1 77.1 59.7 64.8 43.1 63.0 38.0 126.4 59.4 37.2 76.0 56.9 64.5 34.2 80.5 187.8 69.8 155.7 50.4 81.6 52.4 78.5 48.0 54.0 66.1 69.2 51.5 54.9 123.6 57.9 114.3 54.5 84.4 91.1 41.1 42.2 43.1 50.8 42.1 44.5 42.4 42.3 42.4 43.9 41.8 46.5 63.0 64.1 57.5 22.9 44.4 42.6 81.5 159.2 26.7 41.0 39.2 42.2 68.0 42.9 90.4 44.1 25.0 191.9 34.2 85.5 125.2 112.4 48.0 58.4 36.0 54.4 61.6 74.5 29.1 101.3 107.7 48.6 32.6 48.9 44.9 46.2 47.2 36.0 79.6 37.0 28.4 65.0 156.6 45.2 33.6 21.2 56.2 51.6 56.9 26.2 82.3 86.1 54.6 32.2 32.8 132.7 76.2 43.2 47.0 103.0 72.2 126.8 113.4 43.3 46.0 44.7 81.2 177.6 153.7 32.8 48.4 296.1 38.1 91.5 47.8 97.4 TSGA13 ENSG00000213265 "Testis specific 13" Q96PP4 7 130668643-130687432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 103 "testis: 14.0" "Group enriched" "Detected in some" 18 "Early spermatids: 86.4;Late spermatids: 224.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA022968 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA022968: AB_2671013" "unprognostic (1.49e-1)" "unprognostic (1.13e-2)" "unprognostic (1.86e-1)" "unprognostic (1.34e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 3.9 0.0 0.3 1.7 0.1 0.0 0.0 1.2 0.3 0.1 0.1 0.0 1.9 0.0 8.4 0.1 0.3 0.0 0.0 0.0 86.4 0.3 0.3 1.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.4 0.0 0.4 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.9 2.2 224.1 0.6 0.8 0.0 0.0 0.1 0.6 1.0 0.5 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.0 6.0 1.5 0.0 0.0 0.3 1.6 0.6 0.0 0.4 0.7 0.6 0.1 0.0 0.0 TSNAX "C3PO, TRAX" ENSG00000116918 "Translin associated factor X" Q99598 1 231528541-231566524 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 194.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024613, HPA031054, HPA031055, CAB034263" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 36000 "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Golgi apparatus, Cytosol" "CAB034263: AB_2272293, HPA024613: , HPA031054: AB_10600415, HPA031055: AB_10602314" "unprognostic (6.28e-3)" "unprognostic (5.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.12e-1)" "unprognostic (5.55e-2)" "unprognostic (2.27e-1)" "unprognostic (2.96e-2)" "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-3)" "unprognostic (4.51e-2)" "unprognostic (1.91e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-2)" "unprognostic (6.52e-3)" "unprognostic (2.70e-2)" 22.7 31.9 12.2 20.2 12.8 15.1 25.4 11.5 15.1 19.5 17.8 18.4 17.7 21.5 22.8 19.4 18.0 18.7 26.2 13.2 15.2 31.7 26.0 20.8 26.4 11.9 12.7 18.3 16.3 40.0 17.0 20.4 12.3 22.8 19.6 19.9 18.1 20.5 50.5 21.8 17.3 20.7 13.4 28.5 17.7 20.9 13.2 26.6 29.8 40.7 25.7 19.9 14.9 13.7 30.3 24.1 36.7 29.7 27.1 32.6 41.4 33.1 50.9 42.2 36.0 21.4 40.8 42.3 55.0 38.0 15.7 31.9 29.3 31.4 53.9 38.4 51.7 40.7 23.9 28.6 35.8 67.8 82.1 40.4 32.4 40.9 32.3 26.4 30.7 31.6 66.6 28.8 58.0 12.9 44.0 32.9 53.4 26.5 28.3 42.8 39.8 56.8 46.9 33.9 34.1 65.7 35.3 43.3 116.8 14.5 63.2 113.0 28.9 28.3 26.3 57.6 61.0 48.2 68.9 46.4 46.8 52.0 79.7 194.4 34.8 85.6 30.6 40.2 30.3 28.5 33.5 30.6 33.2 28.3 34.6 34.0 37.7 51.9 55.7 22.3 39.4 33.6 12.2 12.8 11.5 15.1 13.2 15.2 11.9 12.7 12.3 13.4 13.2 13.7 48.3 28.9 41.3 0.0 25.5 43.8 21.4 42.4 8.6 59.2 27.2 20.1 24.1 40.0 25.3 42.3 29.2 44.4 36.9 21.8 54.8 30.6 12.6 23.6 20.5 46.1 28.9 59.5 0.0 31.1 51.5 28.1 11.7 19.3 77.3 26.2 31.8 32.8 49.5 65.6 0.0 28.2 38.7 62.2 35.0 9.4 33.5 40.5 26.6 0.0 51.7 72.0 37.0 0.0 0.0 26.5 21.8 36.1 13.4 17.3 22.4 45.8 31.9 47.1 39.5 34.4 30.2 40.8 65.4 13.0 51.4 36.3 30.5 46.8 25.6 14.9 TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.8;Ductal cells: 125.2;Exocrine glandular cells: 189.3;Pancreatic endocrine cells: 193.4;Paneth cells: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 154.7;EFO-21: 211.3;MCF7: 168.0;OE19: 153.2;PC-3: 266.8;SK-BR-3: 134.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" 70.1 5.3 22.8 15.3 37.6 1.0 61.0 35.0 34.1 16.4 14.9 62.5 38.8 32.6 8.5 10.8 24.6 27.4 16.9 23.6 25.4 25.9 4.6 34.4 8.7 36.9 33.4 3.4 20.0 3.2 6.6 28.1 33.7 34.5 39.4 3.1 26.6 24.7 17.9 10.6 38.8 31.3 30.0 26.7 75.3 9.5 34.5 3.6 14.5 5.6 7.5 46.0 14.9 62.4 51.3 103.9 2.1 0.3 2.3 0.0 12.0 0.2 1.9 2.6 6.8 45.1 154.7 0.0 211.3 2.3 9.2 101.2 7.2 11.5 3.0 42.1 20.4 2.9 3.5 10.0 1.1 0.1 1.8 2.2 3.1 1.4 1.5 7.5 39.4 20.5 1.1 0.0 1.2 168.0 0.6 0.9 2.6 153.2 266.8 4.0 2.1 2.0 29.7 92.9 34.5 13.2 0.6 134.8 17.9 17.3 59.3 2.2 34.5 0.2 0.8 0.1 17.5 1.2 6.1 1.0 1.1 0.1 0.2 0.0 0.0 0.0 2.3 0.0 19.5 0.0 3.1 2.8 3.3 0.0 1.0 0.2 0.0 0.1 0.0 0.2 1.1 0.5 22.8 37.6 35.0 34.1 23.6 25.4 36.9 33.4 33.7 30.0 34.5 62.4 108.8 32.1 6.9 4.9 1.5 3.6 10.9 59.6 2.2 2.9 45.1 15.6 1.7 31.5 29.5 29.5 6.2 2.0 1.6 125.8 3.9 125.2 27.9 25.5 3.8 48.4 40.2 8.0 1.7 189.3 11.9 8.2 71.4 36.6 1.3 2.5 10.4 0.1 25.3 1.7 1.0 106.7 36.7 8.5 16.1 6.6 0.6 9.8 28.4 15.0 15.6 44.7 0.0 11.1 75.3 193.4 120.9 0.0 0.2 50.4 68.3 1.8 27.6 1.5 13.1 39.7 26.8 4.3 18.5 2.9 3.1 3.0 3.9 7.5 66.3 29.6 TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "glioma: 54.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: AB_2683447" "unprognostic (2.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (8.96e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (4.31e-3)" "unprognostic (1.19e-1)" "unprognostic (6.51e-3)" "unprognostic (5.31e-2)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "prognostic favorable (9.91e-5)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" 24.5 29.7 9.0 11.2 10.8 5.5 23.1 10.8 15.6 26.2 11.8 20.5 16.4 26.2 13.2 20.4 25.8 20.9 26.7 9.5 10.3 26.7 20.9 22.8 11.8 11.2 10.2 25.6 25.2 32.7 24.4 12.5 11.0 22.1 10.7 29.7 25.6 13.5 21.0 18.6 18.5 8.4 11.1 20.8 23.0 8.0 9.9 9.8 30.2 21.2 8.7 21.0 20.1 13.0 9.5 23.4 21.1 5.4 44.3 24.0 13.5 15.8 11.7 4.6 5.1 16.7 46.4 7.6 32.7 29.0 9.4 17.5 5.7 26.7 10.7 23.1 15.4 10.7 18.7 6.6 45.2 10.6 17.9 29.6 30.2 13.7 30.3 22.1 14.6 4.6 7.5 19.9 19.6 19.4 9.2 5.9 4.3 18.3 7.0 10.5 139.8 20.0 15.7 19.0 6.6 16.7 15.6 21.3 10.5 4.5 41.1 15.8 27.6 11.3 9.5 5.6 7.4 28.9 8.1 4.1 32.7 6.3 19.2 25.4 26.3 16.4 35.8 28.6 34.8 31.1 28.5 30.7 27.6 31.0 28.3 26.2 5.8 35.4 42.0 58.3 22.1 33.0 9.0 10.8 10.8 15.6 9.5 10.3 11.2 10.2 11.0 11.1 9.9 13.0 37.1 48.1 32.4 8.1 23.8 11.2 46.4 37.4 22.2 43.2 32.0 27.4 5.1 20.0 31.4 31.3 41.7 20.9 29.8 19.9 9.8 37.6 1.2 18.5 32.5 26.7 26.5 8.2 9.1 39.0 15.2 31.7 11.7 20.4 45.0 28.9 22.1 21.6 22.4 21.9 9.1 21.6 32.6 18.0 16.4 1.8 25.7 24.2 32.0 8.4 21.6 62.7 35.0 11.1 13.3 37.6 20.3 17.3 18.4 30.5 30.6 18.1 27.9 60.4 19.7 22.3 31.9 9.2 7.7 16.1 12.6 24.5 20.4 35.3 19.4 31.8 TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 422.5;Granulosa cells: 684.8;Late spermatids: 1708.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 6 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "NTERA-2: 121.7;RT4: 153.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: AB_1080301" "unprognostic (7.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.56e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-3)" "unprognostic (2.04e-3)" "unprognostic (8.76e-2)" "unprognostic (3.83e-3)" "unprognostic (4.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (9.54e-3)" 29.6 18.2 7.2 4.9 7.5 0.6 34.2 7.2 8.9 26.9 26.8 40.0 19.7 20.5 14.8 46.8 39.5 16.7 8.6 7.4 9.0 36.5 70.2 11.3 3.0 8.7 9.3 53.4 20.2 34.7 36.9 20.0 8.2 18.9 33.1 6.2 52.6 10.3 4.6 9.7 18.5 7.2 8.9 8.7 14.8 74.9 9.6 4.2 19.3 5.3 6.8 32.2 24.1 12.0 24.8 23.0 80.6 42.2 28.7 16.6 30.4 12.9 17.3 20.3 47.6 54.9 37.7 0.0 53.3 12.2 16.9 19.9 0.3 19.7 25.8 0.1 33.3 3.8 14.9 62.0 17.1 0.1 2.5 30.2 9.3 19.5 6.6 34.4 49.3 0.0 0.0 0.1 21.7 19.8 0.1 0.3 121.7 35.4 18.4 0.0 35.5 0.0 33.0 153.5 4.7 20.3 11.6 10.0 18.5 61.9 16.6 3.3 12.7 16.0 24.4 24.3 8.6 0.1 0.2 0.3 13.4 0.0 11.5 0.3 0.0 0.1 0.3 0.0 1.1 0.1 0.8 0.3 0.0 0.1 2.1 1.2 0.3 0.1 0.1 0.1 0.0 0.3 7.2 7.5 7.2 8.9 7.4 9.0 8.7 9.3 8.2 8.9 9.6 12.0 147.0 3.2 10.1 14.4 2.3 7.1 41.0 75.7 29.0 0.6 72.5 46.1 8.2 50.1 89.4 93.8 0.0 28.7 1.1 94.9 23.5 80.3 422.5 54.0 21.4 37.4 33.6 4.8 0.9 12.6 40.7 25.6 21.9 19.2 0.0 684.8 47.5 104.0 4.5 0.0 0.8 47.9 193.3 10.2 3.1 1708.3 32.9 3.1 10.6 1.0 1.0 48.2 0.0 9.5 0.4 18.7 55.5 35.7 0.3 33.0 43.5 43.8 193.9 1.9 19.7 17.1 43.1 20.9 32.4 23.3 5.4 13.5 2.5 49.4 94.3 89.7 TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 128.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 68.7;Extravillous trophoblasts: 105.1;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 96.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 213.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 58.1" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: AB_2304038" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-2)" "unprognostic (3.53e-2)" "unprognostic (3.11e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-2)" "unprognostic (1.89e-1)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" 25.4 12.9 11.0 7.1 12.1 0.6 25.0 96.6 13.5 29.6 9.7 18.0 7.9 32.3 11.5 15.4 23.2 35.2 128.8 6.9 12.6 45.8 54.8 35.8 5.4 12.3 13.0 35.3 13.1 28.1 8.6 58.7 14.5 27.6 6.2 14.8 18.0 24.4 16.8 27.9 12.3 23.6 8.6 20.6 13.4 5.1 17.1 19.1 18.4 12.4 7.1 18.4 22.3 7.6 1.5 12.7 20.1 16.1 19.2 15.5 48.3 26.7 82.3 20.1 26.1 30.6 11.6 0.8 23.9 14.6 19.7 3.1 9.5 9.6 11.8 5.0 9.3 36.3 8.5 20.6 42.2 0.2 3.0 17.7 7.4 40.4 16.9 50.4 55.7 1.1 1.0 1.1 17.6 16.7 0.0 0.8 25.5 7.8 7.4 9.9 213.0 3.1 61.7 7.4 36.8 22.6 18.8 36.6 16.4 45.9 13.7 0.2 27.2 8.5 28.8 14.8 25.7 0.2 0.6 0.3 20.3 0.5 10.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.2 11.0 12.1 96.6 13.5 6.9 12.6 12.3 13.0 14.5 8.6 17.1 7.6 60.1 0.0 4.1 10.4 0.8 19.2 13.3 22.4 13.1 68.7 19.8 9.0 50.1 11.5 6.5 12.9 2.1 53.1 0.2 1.7 5.9 21.1 3.0 2.3 24.9 43.1 6.0 5.3 16.8 9.1 105.1 22.2 2.0 5.7 0.0 13.0 41.0 36.7 6.2 33.7 45.5 2.3 2.0 3.2 3.5 4.1 17.4 7.1 12.4 30.9 0.8 4.0 0.0 9.0 2.0 9.9 0.6 17.3 1.4 13.8 2.4 22.4 2.5 4.7 19.7 1.4 20.9 1.3 3.4 9.7 11.9 80.7 1.5 6.4 2.5 10.5 TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS" ENSG00000100300 "Translocator protein" "B1AH88, P30536" 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 690.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1429.2;Pancreatic endocrine cells: 1442.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 516.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" 249.3 164.5 42.3 65.3 46.3 488.7 204.3 50.9 61.1 217.3 45.8 189.7 73.6 91.8 8.7 690.1 108.5 39.4 174.7 39.9 51.0 120.5 81.9 181.5 44.3 61.9 48.8 72.3 93.4 22.4 50.8 30.5 57.4 126.6 33.9 4.2 244.9 28.9 84.0 388.0 116.9 26.6 58.0 206.9 216.9 21.4 59.5 22.2 77.4 27.5 39.9 135.7 355.5 69.0 300.0 143.3 10.2 134.4 54.7 175.3 10.8 216.6 107.0 109.4 115.7 28.8 222.4 0.3 147.8 175.7 52.2 242.2 27.9 171.7 13.9 49.5 111.4 28.9 150.4 10.1 193.4 66.4 145.0 137.5 276.4 65.9 58.2 125.8 262.9 0.2 24.0 53.6 114.2 244.5 1.1 188.5 11.6 154.0 355.7 67.0 0.0 516.2 139.3 173.8 14.0 65.4 103.9 200.4 263.5 0.1 76.3 256.6 269.7 132.6 96.9 135.5 92.9 21.7 4.1 2.7 170.0 218.3 171.4 656.8 1678.5 931.0 314.7 1051.6 247.7 199.2 429.9 309.2 1170.2 266.9 325.9 264.3 1052.3 365.0 713.1 209.0 539.5 1585.6 42.3 46.3 50.9 61.1 39.9 51.0 61.9 48.8 57.4 58.0 59.5 69.0 225.5 160.3 140.0 3.6 88.9 366.8 392.3 1429.2 554.3 2.8 269.3 360.2 92.1 323.1 555.7 206.0 2.1 10.0 140.3 680.7 369.8 578.5 2.4 170.8 143.6 220.4 194.9 239.9 0.3 586.4 284.9 205.1 440.9 309.5 268.6 124.3 187.1 110.5 758.5 3.3 0.8 636.8 478.1 644.7 524.7 11.7 82.6 611.6 723.9 10.3 776.9 180.5 207.0 6.0 20.1 1442.1 705.9 157.6 76.3 526.2 471.9 180.7 283.2 19.4 105.2 108.2 197.8 2.8 4.5 1067.4 536.0 20.0 180.0 30.5 664.1 786.1 TSPYL6 ENSG00000178021 "TSPY like 6" Q8N831 2 54253178-54256229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 21.5" "Group enriched" "Detected in some" 6 "Spermatocytes: 33.9;Spermatogonia: 22.5" "Cancer enriched" "Detected in single" 27 "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 69 "K-562: 8.3" "HPA034699, HPA034700" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Cytosol" "HPA034699: AB_2674288, HPA034700: AB_10670159" "unprognostic (8.21e-2)" "unprognostic (4.25e-1)" "unprognostic (1.06e-2)" "unprognostic (1.00e-1)" "unprognostic (5.54e-6)" "unprognostic (4.50e-2)" "unprognostic (1.77e-1)" "unprognostic (5.73e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.7 0.1 0.3 0.3 0.0 0.4 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 33.9 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 12.7;testis: 34.0" "Group enriched" "Detected in some" 67 "Early spermatids: 335.4;Late spermatids: 1251.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: AB_2675517" "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 2.3 2.7 0.1 2.5 0.2 12.7 2.0 2.2 0.4 2.9 0.3 2.1 3.4 2.3 0.0 1.3 2.7 1.8 1.5 0.1 0.0 1.9 2.7 2.7 3.8 0.5 0.0 3.0 2.1 0.0 1.7 0.7 0.2 2.1 0.0 4.3 2.4 0.0 3.0 4.7 4.0 0.1 0.0 4.3 2.2 34.0 0.2 0.0 2.3 0.0 0.0 1.7 2.3 0.5 2.4 2.8 6.0 3.6 0.0 0.8 5.2 0.6 0.9 0.0 0.0 0.5 1.3 1.4 0.8 0.0 1.0 3.5 0.0 0.0 0.0 3.6 6.8 2.8 14.1 4.3 3.3 1.3 3.2 0.1 0.7 0.0 1.0 6.7 0.0 4.5 3.5 5.5 0.0 0.7 1.5 1.5 1.1 0.5 1.6 2.1 1.6 4.7 0.0 2.4 1.7 3.8 0.8 3.0 3.9 4.5 1.8 2.4 2.4 2.1 2.9 3.0 2.4 7.6 3.3 1.9 3.5 4.3 0.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 2.2 0.4 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.5 0.4 0.0 0.5 0.7 0.3 0.1 0.4 0.3 0.0 0.2 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.3 335.4 0.4 0.6 0.5 0.0 0.0 0.0 0.7 0.1 0.3 0.0 0.5 0.0 1.4 0.7 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 1251.0 9.3 0.3 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.3 0.1 9.4 0.0 0.2 0.7 0.8 0.8 1.2 6.6 0.2 0.2 11.7 3.7 0.0 0.0 0.3 0.2 0.5 0.3 0.3 TTC28 KIAA1043 ENSG00000100154 "Tetratricopeptide repeat domain 28" Q96AY4 22 27978014-28679865 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 291.5;Excitatory neurons: 169.6;Inhibitory neurons: 289.8;Microglial cells: 332.6;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001080 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge, Mitotic spindle" Cytosol "HPA001080: " "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-1)" "unprognostic (8.55e-3)" "unprognostic (4.83e-2)" "unprognostic (5.20e-2)" "unprognostic (2.25e-1)" "prognostic favorable (4.30e-4)" "unprognostic (3.91e-2)" "unprognostic (1.18e-2)" "unprognostic (5.40e-2)" "unprognostic (5.10e-2)" "prognostic favorable (5.65e-5)" "unprognostic (5.54e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (4.36e-1)" 7.2 4.6 4.3 2.9 3.0 0.8 6.3 0.4 3.4 8.8 2.6 6.9 3.1 10.2 9.8 5.2 8.7 6.4 4.9 3.9 1.8 4.9 3.5 7.2 2.0 2.4 2.0 16.8 5.0 3.8 3.8 8.8 1.4 5.1 2.9 3.4 6.8 6.9 5.4 3.0 3.8 8.5 1.8 3.5 4.8 8.1 2.1 2.7 6.8 5.1 1.4 6.3 5.0 2.1 0.0 6.8 17.1 7.4 10.0 14.8 0.3 5.1 9.4 7.1 6.1 0.5 0.0 0.1 6.9 14.9 2.3 1.0 11.1 0.3 3.8 0.7 7.5 1.1 8.6 6.5 4.5 0.2 6.8 14.9 0.3 4.6 3.2 4.8 13.0 4.5 4.5 0.6 1.6 2.5 0.1 0.6 3.1 0.0 4.3 7.0 4.3 0.1 3.3 0.2 4.8 10.6 7.1 0.2 4.5 4.7 3.5 0.6 12.2 8.4 4.0 5.5 3.8 2.2 0.2 0.1 3.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 4.3 3.0 0.4 3.4 3.9 1.8 2.4 2.0 1.4 1.8 2.1 2.1 29.4 3.2 12.5 291.5 3.2 6.0 5.8 1.7 11.4 34.1 8.7 8.0 9.7 8.6 1.6 12.9 18.8 6.0 2.3 2.1 0.0 6.2 10.8 7.9 28.9 30.9 9.0 7.0 169.6 6.0 1.5 27.3 4.1 12.4 1.3 32.3 36.8 15.3 3.7 28.6 289.8 5.8 0.0 9.4 7.2 9.1 31.4 4.3 10.6 332.6 0.7 11.5 5.2 318.7 116.3 3.9 4.4 45.5 3.1 5.0 4.8 18.6 1.9 24.9 13.1 27.2 19.7 23.8 11.6 6.7 3.8 2.5 3.2 27.4 6.9 4.0 TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: AB_2675049" "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" 45.8 29.3 28.1 27.1 25.0 26.4 43.1 36.3 35.3 59.3 45.7 34.6 24.7 38.9 58.6 27.9 34.9 35.4 28.0 38.9 15.5 37.7 31.7 24.4 29.4 10.0 11.1 60.6 42.9 39.1 35.6 29.0 11.8 51.2 36.3 63.0 50.0 41.4 27.7 30.7 30.3 34.6 6.7 27.3 40.9 27.4 15.3 38.0 64.8 30.6 29.2 30.6 9.4 21.4 72.9 25.4 115.3 22.2 108.9 156.8 40.0 77.5 96.0 34.2 46.1 34.0 35.8 62.3 26.6 130.9 32.1 23.3 35.3 47.9 48.2 66.3 25.0 125.6 38.0 44.1 39.6 70.9 39.1 81.9 28.8 35.0 31.0 68.8 51.6 54.1 77.3 71.1 65.2 56.0 69.4 18.8 33.3 48.0 42.6 91.6 55.3 33.2 39.4 55.3 87.7 67.6 97.2 55.2 49.1 26.5 62.2 27.3 68.3 49.2 19.5 61.2 30.4 71.1 55.1 60.6 80.7 69.9 37.9 4.8 6.2 6.8 11.5 6.4 17.1 13.0 13.3 15.8 10.8 15.1 23.2 14.4 1.0 12.8 8.6 17.3 10.0 4.8 28.1 25.0 36.3 35.3 38.9 15.5 10.0 11.1 11.8 6.7 15.3 21.4 78.3 125.0 142.7 161.3 144.8 65.9 94.8 102.7 86.0 347.7 175.8 140.1 134.7 68.6 118.2 75.4 227.2 50.1 129.5 67.8 166.3 91.1 192.7 115.0 217.4 78.9 190.2 65.4 424.5 75.3 93.5 171.0 131.5 132.0 64.6 256.8 99.6 94.4 61.4 329.7 396.0 163.1 99.7 95.2 83.7 192.4 210.0 86.8 211.7 111.5 87.4 196.5 93.7 321.7 261.9 73.3 96.5 261.1 167.6 121.4 72.8 96.1 108.6 233.9 52.6 245.8 127.9 400.0 258.4 91.7 62.8 52.7 109.7 204.1 148.1 103.9 TTC33 OSRF ENSG00000113638 "Tetratricopeptide repeat domain 33" Q6PID6 5 40512333-40755963 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038252, HPA038253" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Golgi apparatus, Vesicles" "HPA038252: AB_10674551, HPA038253: AB_10671739" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (3.41e-3)" "unprognostic (1.04e-3)" "unprognostic (3.01e-2)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.50e-2)" "unprognostic (1.29e-1)" "unprognostic (2.04e-2)" "unprognostic (4.28e-3)" 6.9 5.9 6.6 3.3 7.2 0.8 5.7 10.0 9.7 5.8 5.3 6.3 4.3 6.2 4.7 4.2 5.6 4.6 6.3 7.5 6.6 7.5 7.7 5.1 4.3 6.3 6.5 6.7 4.8 8.9 4.4 4.1 6.3 5.9 4.2 11.6 5.3 5.6 15.5 3.8 4.8 5.0 5.6 4.6 5.2 4.5 7.3 6.7 6.0 14.8 4.1 5.4 5.2 6.9 3.6 3.2 6.1 6.8 5.0 7.1 2.9 4.7 5.6 4.8 5.1 1.7 3.5 11.0 2.8 4.3 5.2 1.6 5.2 2.7 8.5 10.3 4.9 2.4 13.5 4.3 5.5 6.5 3.1 4.4 5.6 4.8 5.0 8.4 7.2 7.3 5.8 8.3 6.4 1.0 12.5 9.3 1.9 2.8 3.5 11.1 11.5 7.9 8.2 2.1 4.5 6.2 11.0 6.4 8.1 5.0 4.3 8.7 5.5 5.5 4.6 4.3 4.6 6.0 6.7 5.8 5.1 10.1 4.9 7.1 1.8 3.2 2.0 4.4 2.2 2.1 2.3 2.1 1.9 2.2 2.5 2.2 2.5 2.3 6.6 1.0 2.2 1.9 6.6 7.2 10.0 9.7 7.5 6.6 6.3 6.5 6.3 5.6 7.3 6.9 12.9 16.0 7.4 9.8 13.1 14.4 5.6 8.6 11.4 12.3 8.6 6.0 18.2 7.2 6.2 7.3 6.2 5.9 8.8 6.9 19.6 8.2 22.4 9.1 11.5 11.0 3.0 9.5 23.7 6.3 4.2 12.6 6.1 6.8 12.7 8.9 13.9 9.4 5.1 5.0 27.5 8.0 10.2 7.5 15.4 8.4 14.0 7.5 10.6 15.9 14.3 19.2 2.1 23.6 35.1 8.0 8.4 13.9 11.8 6.8 6.8 12.6 13.7 23.5 13.1 9.9 13.4 28.1 22.1 6.3 18.3 2.6 14.6 5.0 6.2 4.5 TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218399 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "brain: 110.8;choroid plexus: 32.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.1;Excitatory neurons: 39.3;Horizontal cells: 18.5;Inhibitory neurons: 19.7;Oligodendrocyte precursor cells: 27.2" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: AB_10795506" "unprognostic (2.31e-1)" "unprognostic (1.39e-4)" "unprognostic (5.09e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.54e-2)" "unprognostic (3.69e-1)" "unprognostic (8.75e-6)" "unprognostic (1.39e-1)" "unprognostic (8.23e-2)" "unprognostic (1.95e-1)" "unprognostic (5.24e-2)" 0.0 0.6 73.9 0.3 74.7 0.0 0.0 49.7 110.8 0.0 32.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.2 60.6 0.2 0.0 0.0 0.0 45.1 46.3 0.0 0.0 0.0 0.9 0.0 46.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.1 43.0 0.0 0.2 0.3 60.4 0.0 0.0 0.0 0.0 0.0 0.1 69.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 26.8 1.4 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 73.9 74.7 49.7 110.8 84.2 60.6 45.1 46.3 46.4 43.0 60.4 69.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 39.1 0.2 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.8 0.2 0.2 1.8 0.0 39.3 0.5 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 18.5 19.7 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 4.7 0.0 1.7 0.0 27.2 5.0 0.1 1.2 0.7 0.0 0.1 0.0 0.0 1.2 8.4 0.0 0.0 0.1 7.0 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 2296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 170000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB005417: AB_2241191, CAB012406: AB_2210370, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (1.01e-1)" "unprognostic (2.33e-1)" "unprognostic (2.17e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (2.18e-3)" "unprognostic (1.27e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.62e-8)" "unprognostic (8.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" 229.5 164.8 74.6 243.5 81.8 541.0 186.9 46.2 367.7 228.7 87.0 250.3 87.6 333.0 174.5 246.3 227.0 158.5 245.3 73.5 119.7 137.8 236.6 205.3 369.2 80.5 74.8 467.5 138.1 74.4 97.0 194.4 99.2 145.2 194.4 82.4 160.2 194.6 185.7 211.9 159.4 371.0 57.5 195.0 172.8 77.8 94.0 620.4 142.4 98.6 487.6 222.3 213.8 63.5 2281.7 1027.3 2650.0 1458.4 733.2 1265.2 568.2 396.9 469.5 943.3 863.5 1329.2 703.9 1494.1 1105.1 1408.1 1877.8 805.3 2160.6 1968.0 160.3 892.5 1321.1 461.4 207.3 1306.7 345.8 2550.0 1223.9 943.6 455.9 416.0 443.6 967.1 1493.3 2058.1 1270.4 294.1 1844.8 1398.2 2719.0 249.3 377.3 604.1 948.6 102.6 708.5 911.6 1564.5 1071.4 940.8 1516.7 969.0 911.2 354.7 1625.5 1148.3 422.4 880.6 2712.0 1526.0 614.5 917.7 835.3 1735.4 2101.3 538.8 2494.6 3548.7 119.8 115.6 122.8 187.3 182.5 218.8 166.1 152.3 188.8 111.7 113.0 143.2 163.3 46.8 165.1 222.4 227.7 180.8 342.5 74.6 81.8 46.2 367.7 73.5 119.7 80.5 74.8 99.2 57.5 94.0 63.5 215.8 131.4 47.3 21.5 214.9 576.2 358.4 698.6 434.2 72.7 234.2 312.8 114.9 244.5 238.7 171.0 39.6 811.9 198.7 133.4 311.0 1091.0 9.1 69.1 261.6 370.8 163.6 1322.1 28.2 1061.1 2296.1 471.5 95.3 140.2 207.3 643.6 298.4 267.8 955.2 109.4 25.0 185.3 376.4 454.5 689.6 24.4 402.6 295.8 321.9 30.9 774.0 192.6 246.1 20.1 23.0 1087.0 90.7 237.3 304.6 199.5 117.9 245.9 66.6 65.4 118.3 124.0 838.6 58.0 126.5 447.0 430.6 220.4 244.0 224.9 253.2 229.0 TUBB1 dJ543J19.4 ENSG00000101162 "Tubulin beta 1 class VI" Q9H4B7 20 59019429-59026654 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;lymphoid tissue: 4.3" "Cell type enriched" "Detected in some" 10 "Macrophages: 191.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "basophil: 63.5;neutrophil: 26.0" "Lineage enriched" "Detected in many" 24 "granulocytes: 63.5" "Cell line enriched" "Detected in some" 19 "HEL: 29.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004286, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 87000000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB004286: AB_2288090, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (3.76e-1)" "unprognostic (2.69e-1)" "unprognostic (6.10e-4)" "unprognostic (1.02e-1)" "unprognostic (5.00e-2)" "unprognostic (2.02e-1)" "unprognostic (5.86e-2)" "unprognostic (7.51e-4)" "unprognostic (1.90e-2)" "unprognostic (2.63e-1)" "unprognostic (6.80e-5)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "unprognostic (1.00e-1)" 0.2 0.2 0.2 0.3 0.2 8.5 0.1 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.3 2.4 0.2 0.3 0.2 0.1 0.1 0.0 0.3 1.1 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.1 4.3 0.1 0.9 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.3 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 29.5 0.8 1.5 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.4 0.0 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.2 0.6 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.1 0.2 0.4 63.5 2.4 1.9 0.5 0.6 0.4 0.9 0.2 0.0 1.1 0.5 0.4 0.0 26.0 0.2 0.3 2.6 0.5 281.6 0.2 0.2 0.5 0.5 0.1 0.2 0.3 0.2 0.2 0.1 0.2 0.3 0.1 0.0 1.1 0.3 1.4 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.1 0.0 0.6 0.0 4.2 0.0 3.1 0.0 0.0 0.0 16.0 0.3 0.2 1.5 0.0 19.0 0.2 0.0 0.1 0.1 0.0 0.7 1.3 0.0 3.6 0.2 0.3 0.0 0.2 0.0 0.0 2.8 0.0 5.9 0.3 191.2 0.0 0.0 13.8 0.2 13.4 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 1.0 0.1 0.1 0.1 TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 516.5;Suprabasal keratinocytes: 368.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in all" "AF22: 241.1;CACO-2: 247.6;SuSa: 365.5;WM-115: 280.1" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" 58.8 17.8 266.1 19.3 251.1 67.5 47.8 130.1 287.5 32.7 10.0 78.0 24.2 50.8 28.0 90.6 23.5 21.5 29.4 248.3 364.3 31.1 67.0 16.4 11.0 292.6 212.2 15.5 39.4 2.2 56.3 23.9 334.3 17.5 8.2 49.9 52.2 15.6 22.3 151.4 34.9 41.7 131.6 7.7 41.0 9.5 204.4 6.4 10.0 11.8 9.6 23.6 51.2 169.4 55.9 45.3 241.1 53.6 30.6 34.0 14.5 119.8 44.7 80.6 115.7 247.6 18.4 27.4 72.9 115.5 80.2 26.0 86.6 26.8 28.0 134.1 57.7 9.4 11.4 77.0 31.6 1.5 8.4 35.1 31.1 85.1 5.3 28.9 37.3 10.6 33.7 8.8 74.2 25.1 14.9 2.8 207.2 16.0 58.3 12.4 22.6 18.9 28.0 27.4 57.6 52.9 30.5 8.5 179.7 365.5 19.1 2.0 76.0 53.9 56.7 117.3 65.8 3.2 4.6 18.8 19.7 7.0 280.1 0.0 1.1 0.0 2.2 1.6 2.4 3.2 2.1 3.1 0.5 0.6 1.0 2.0 0.3 0.4 1.3 0.2 3.2 1.2 266.1 251.1 130.1 287.5 248.3 364.3 292.6 212.2 334.3 131.6 204.4 169.4 125.3 16.0 13.1 43.1 31.6 311.4 63.3 87.0 132.6 105.6 32.0 134.6 20.4 42.9 62.7 12.9 16.7 6.0 53.4 87.0 217.2 54.0 60.9 46.7 29.6 40.6 73.1 322.3 59.9 182.4 50.4 96.2 185.0 57.9 34.9 10.1 12.5 55.6 50.8 516.5 73.0 103.9 73.2 6.3 164.4 32.9 20.8 36.7 129.9 24.4 72.7 261.0 0.0 18.1 23.0 103.4 181.8 15.4 15.8 34.9 126.3 40.4 50.3 86.2 6.6 95.6 87.9 32.4 14.9 140.6 368.5 6.2 58.9 6.4 60.0 54.7 TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 387.9;choroid plexus: 154.0" "Group enriched" "Detected in many" 4 "Distal tubular cells: 414.8;Horizontal cells: 430.7;Muller glia cells: 847.3;Skeletal myocytes: 350.1" "Cancer enriched" "Detected in many" 9 "glioma: 216.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 541.9;CACO-2: 415.3;NTERA-2: 268.0;RPMI-8226: 277.7;SCLC-21H: 797.7;SH-SY5Y: 390.2;SuSa: 245.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (5.92e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.81e-2)" "unprognostic (3.26e-2)" "unprognostic (9.03e-3)" "unprognostic (8.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.78e-3)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "unprognostic (6.24e-3)" "unprognostic (6.04e-2)" "unprognostic (3.58e-4)" "unprognostic (2.30e-3)" 4.0 7.2 298.1 8.1 324.5 1.0 5.0 348.4 387.9 9.9 154.0 17.0 2.4 4.2 45.5 2.4 3.3 3.8 4.6 258.8 356.9 11.6 1.0 1.4 8.1 363.3 349.9 1.1 5.7 0.0 35.1 4.4 354.5 3.7 2.6 65.3 10.8 4.6 6.2 3.9 6.1 7.3 337.2 0.7 4.5 1.0 369.1 2.3 0.9 1.6 5.7 2.6 5.6 383.9 0.0 8.2 541.9 164.2 0.6 0.2 0.9 5.1 7.4 20.8 45.0 415.3 2.0 0.9 5.6 5.7 0.0 1.3 212.8 0.7 12.0 1.6 98.3 0.2 0.0 33.2 1.1 0.1 6.1 3.1 0.0 2.3 0.0 7.6 1.4 0.5 6.8 1.2 7.6 0.3 1.5 0.4 268.0 1.0 17.6 0.6 26.3 277.7 2.9 0.8 797.7 390.2 0.3 1.7 4.3 245.9 3.2 0.0 0.0 1.9 89.9 6.3 2.2 51.6 0.1 0.0 0.8 0.1 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.1 324.5 348.4 387.9 258.8 356.9 363.3 349.9 354.5 337.2 369.1 383.9 3.6 0.0 0.0 109.4 1.9 8.7 2.3 1.8 4.6 63.5 3.9 31.9 40.1 5.7 0.3 7.3 16.7 0.7 1.0 0.9 414.8 15.4 5.8 2.7 3.3 7.6 66.7 0.0 2.4 3.5 1.2 18.7 7.1 3.9 0.0 0.5 0.7 0.6 3.0 430.7 19.4 1.0 24.4 0.0 12.4 7.1 0.3 1.0 92.5 9.4 3.6 847.3 0.0 37.2 21.6 12.0 0.1 0.0 8.4 3.9 0.2 2.0 0.0 43.1 0.0 350.1 19.1 1.3 6.2 3.1 2.7 0.8 0.6 0.0 0.6 1.1 TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 313.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Ductal cells: 28.7;Excitatory neurons: 37.9;Exocrine glandular cells: 21.4;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 45.1;Pancreatic endocrine cells: 49.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Cell line enhanced" "Detected in many" "A549: 421.3;SCLC-21H: 424.9;SH-SY5Y: 433.8" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 89000000 "Cluster 24: B-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (7.08e-2)" "unprognostic (3.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (8.01e-2)" "unprognostic (3.12e-2)" "unprognostic (4.04e-3)" "unprognostic (1.12e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (7.57e-2)" "unprognostic (1.27e-3)" "unprognostic (3.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.91e-2)" 5.7 24.8 99.4 12.1 93.3 3.4 2.1 100.5 127.6 3.3 0.0 18.4 3.7 9.7 0.2 3.6 2.3 8.8 5.5 88.6 313.3 13.3 0.9 4.1 7.1 208.8 132.7 3.9 3.2 0.4 55.1 1.8 266.2 3.0 2.6 24.8 10.6 0.4 0.6 5.2 8.0 12.7 74.2 1.3 7.2 38.0 183.4 1.0 2.5 0.3 5.2 7.3 5.3 82.5 30.1 421.3 152.6 173.9 17.9 170.8 6.8 181.0 31.0 105.8 48.2 57.2 53.5 89.6 93.6 136.8 74.3 112.1 148.9 26.7 26.3 22.7 15.5 0.7 32.5 383.7 6.0 0.0 67.6 98.4 7.9 161.9 14.0 136.8 88.4 5.9 9.2 2.5 122.3 288.6 1.2 31.5 274.3 11.2 237.3 0.1 54.1 9.5 131.8 8.1 424.9 433.8 251.2 4.4 137.1 27.5 15.0 1.9 110.9 142.8 156.9 197.3 185.3 1.4 19.6 35.2 150.2 11.5 260.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 99.4 93.3 100.5 127.6 88.6 313.3 208.8 132.7 266.2 74.2 183.4 82.5 0.4 0.0 0.0 20.2 0.0 0.0 0.0 0.0 3.4 1.8 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.0 28.7 8.2 0.5 2.6 3.8 4.9 0.0 37.9 21.4 0.7 6.1 27.0 0.7 0.0 0.0 0.0 0.0 0.2 5.0 45.1 0.1 0.0 0.0 0.0 16.8 0.3 0.2 0.0 9.4 0.0 0.3 0.0 16.1 9.2 49.2 0.0 0.4 0.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 5.1 0.2 0.4 3.0 0.0 1.0 0.1 0.0 0.2 0.0 TUBB4A "beta-5, DYT4, TUBB4" ENSG00000104833 "Tubulin beta 4A class IVa" P04350 19 6494319-6502848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Dystonia, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 828.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 22.2;Muller glia cells: 33.0;Oligodendrocytes: 94.1;Theca cells: 81.7" "Group enriched" "Detected in many" 9 "glioma: 50.1;melanoma: 83.2;testis cancer: 49.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 13 "B-cells: 3.8;T-cells: 5.4" "Cell line enhanced" "Detected in many" "AN3-CA: 100.7;HAP1: 58.3;HEL: 91.7;PC-3: 49.6;REH: 43.4;SH-SY5Y: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010768, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 110000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010768: AB_261775, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (8.42e-7)" "unprognostic (3.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (8.08e-2)" "unprognostic (6.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (1.12e-3)" "unprognostic (1.36e-2)" "unprognostic (1.58e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" 0.9 203.4 209.7 1.7 404.6 0.2 0.6 452.3 388.7 0.6 0.0 6.3 1.1 0.6 0.3 0.7 0.9 0.6 2.5 249.2 229.1 2.2 1.2 0.6 1.1 425.9 254.4 1.5 3.0 0.6 4.0 0.7 440.0 0.8 0.8 22.6 1.2 0.4 4.4 5.2 3.0 0.8 221.4 9.5 2.1 76.0 373.5 0.3 0.6 1.0 0.7 0.6 1.8 828.2 0.2 28.3 0.1 100.7 0.2 0.0 0.2 0.7 0.0 0.1 0.0 1.4 0.4 0.1 30.3 0.0 3.5 0.7 58.3 0.0 0.6 0.0 10.7 91.7 1.9 0.9 0.0 0.0 5.5 0.0 0.0 2.3 0.0 1.0 0.0 17.1 8.6 0.8 0.0 3.0 18.1 4.1 7.5 0.0 49.6 43.4 0.1 20.3 10.9 0.1 0.2 36.6 0.3 0.2 30.9 2.7 0.8 1.9 0.0 0.2 12.2 0.1 0.4 2.4 1.7 11.7 1.1 0.1 0.5 0.0 0.0 0.0 5.4 0.0 3.3 3.8 0.7 5.0 0.0 1.1 1.6 3.8 0.1 0.3 0.0 0.0 0.0 1.4 209.7 404.6 452.3 388.7 249.2 229.1 425.9 254.4 440.0 221.4 373.5 828.2 0.1 0.0 0.0 6.8 3.2 1.9 0.7 0.3 0.0 2.8 0.1 0.1 9.8 1.5 0.0 0.0 0.0 0.2 1.6 0.1 5.9 1.6 2.9 0.1 0.2 1.2 0.0 2.1 22.2 0.0 0.2 1.8 0.0 0.1 0.0 16.3 1.4 0.3 0.4 10.1 15.0 0.0 0.0 0.0 1.2 9.4 5.3 0.3 14.2 13.1 0.0 33.0 1.0 8.5 94.1 0.1 0.0 0.4 0.9 0.2 0.0 1.8 0.5 2.3 6.6 0.4 4.6 1.9 1.1 0.0 1.6 0.1 3.8 81.7 0.0 0.2 TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2190.0;Late spermatids: 2907.1;Spermatocytes: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010880: AB_609915, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (9.98e-4)" "unprognostic (9.92e-3)" "unprognostic (2.90e-1)" "unprognostic (3.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.09e-2)" "unprognostic (2.47e-3)" "unprognostic (6.37e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.36e-6)" "unprognostic (1.69e-1)" 134.5 112.6 162.0 97.2 163.4 423.9 94.4 149.4 182.7 88.1 482.7 198.3 142.0 107.7 209.1 343.3 507.2 106.0 435.8 174.0 185.2 122.5 140.1 130.5 95.5 184.1 233.6 72.9 123.8 87.8 118.0 86.3 213.9 120.2 111.9 261.8 177.9 121.5 202.5 240.0 166.4 119.8 162.9 85.6 161.4 765.7 192.6 162.9 115.7 96.6 119.7 188.3 139.4 133.9 706.2 1032.5 431.7 314.2 213.2 223.6 600.5 643.7 536.0 872.4 598.6 1101.0 840.2 429.0 480.2 631.2 848.2 1305.1 539.5 1039.2 330.2 307.9 458.5 311.2 789.6 877.8 134.5 370.0 331.5 145.0 291.5 667.5 183.1 215.7 631.7 300.6 443.0 239.7 731.2 1936.4 337.4 504.2 457.8 1234.8 1778.1 423.5 822.2 394.2 666.8 647.8 301.5 323.6 853.9 485.8 173.2 244.2 699.0 397.6 495.6 618.1 685.0 710.0 863.6 92.4 274.9 475.1 503.6 286.9 549.8 95.7 30.0 43.2 40.5 30.1 38.2 32.6 31.3 34.4 34.9 30.8 19.7 26.7 56.4 24.4 30.5 36.3 44.7 32.6 162.0 163.4 149.4 182.7 174.0 185.2 184.1 233.6 213.9 162.9 192.6 133.9 478.5 221.2 146.3 21.5 315.8 326.2 945.7 458.7 327.2 508.1 286.9 389.5 91.9 143.0 284.1 143.5 300.3 346.6 640.9 744.1 221.1 348.6 2190.0 1191.6 224.8 203.9 391.5 419.9 30.1 446.8 545.5 247.8 274.7 415.0 189.2 200.9 142.5 139.2 265.9 244.0 24.3 503.6 323.5 59.9 214.9 2907.1 254.2 299.3 138.7 22.5 224.0 299.3 49.4 15.6 19.7 477.4 697.2 153.1 264.0 475.1 540.7 345.5 1558.7 763.3 111.7 261.8 416.0 1717.5 740.9 419.1 297.6 321.1 362.9 89.8 487.3 592.7 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TUBB8 bA631M21.2 ENSG00000261456 "Tubulin beta 8 class VIII" Q3ZCM7 10 46888-74163 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.4;Early spermatids: 11.7;Late spermatids: 3.4;Spermatocytes: 13.0;Spermatogonia: 15.9" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.3" "HPA043640, HPA046280" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 49: Eosinophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.75e-2)" "unprognostic (6.02e-2)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-1)" "unprognostic (1.80e-1)" "unprognostic (7.74e-2)" "unprognostic (8.33e-3)" "unprognostic (1.50e-1)" "unprognostic (4.15e-3)" "unprognostic (7.17e-2)" "unprognostic (3.30e-2)" "unprognostic (1.33e-3)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.19e-2)" "unprognostic (6.86e-3)" 0.1 0.1 0.4 0.1 0.4 0.0 0.2 0.3 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.3 0.3 0.7 0.0 0.1 0.1 0.3 0.3 0.4 0.3 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.3 0.1 2.4 0.3 0.0 0.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.1 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.4 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 13.0 15.9 0.0 0.0 0.0 0.0 0.4 0.0 0.6 TUBB8B TUBB8P12 ENSG00000173213 "Tubulin beta 8B" A6NNZ2 18 47390-49557 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 2.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.29e-1)" "unprognostic (6.73e-2)" "unprognostic (1.76e-1)" "unprognostic (6.91e-2)" "unprognostic (1.92e-1)" "unprognostic (4.36e-2)" "unprognostic (1.29e-1)" "unprognostic (2.09e-1)" "unprognostic (4.46e-2)" "unprognostic (7.42e-4)" "unprognostic (3.96e-2)" "unprognostic (5.98e-2)" "unprognostic (4.88e-2)" "unprognostic (3.21e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA015285: AB_1858460, HPA018496: AB_2669889" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.99e-4)" "unprognostic (2.45e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (7.52e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (3.19e-2)" 21.0 17.1 13.6 7.5 14.2 2.6 18.3 19.2 16.1 33.3 15.8 21.6 5.4 23.2 11.7 17.8 24.3 12.1 17.7 13.8 13.2 17.3 9.0 13.5 6.1 16.3 14.8 37.7 9.6 13.3 12.3 13.7 13.8 15.4 8.2 12.7 13.0 13.9 10.4 25.7 10.5 18.2 14.5 9.4 15.5 13.0 14.4 9.4 15.5 9.7 8.1 16.7 24.1 17.1 22.6 18.8 35.0 29.1 34.3 51.0 32.9 34.5 57.5 36.4 40.2 24.0 20.4 16.7 5.1 51.2 31.2 18.5 21.1 22.2 42.0 21.7 15.4 10.0 23.4 15.5 44.3 10.8 11.1 30.1 25.7 55.3 74.9 44.6 28.6 20.8 9.7 15.1 31.0 20.3 16.1 9.4 47.4 17.8 13.7 16.8 34.2 6.3 22.9 18.7 8.8 23.4 30.1 17.8 19.9 63.4 22.2 10.5 23.0 26.6 32.0 54.7 33.9 4.7 6.0 14.3 26.9 5.9 41.5 0.0 0.9 0.3 2.1 0.8 3.5 1.6 1.7 2.2 0.7 1.8 2.0 2.8 0.4 2.7 0.5 1.6 3.3 1.0 13.6 14.2 19.2 16.1 13.8 13.2 16.3 14.8 13.8 14.5 14.4 17.1 12.9 6.4 10.5 70.5 6.2 20.3 16.9 14.8 26.2 6.1 9.9 12.2 8.0 18.6 15.9 1.8 2.1 9.4 6.0 4.6 23.5 17.3 5.8 35.1 33.5 15.2 3.6 6.1 6.0 7.3 10.6 31.7 6.6 14.6 0.0 11.5 24.3 5.5 5.3 40.4 10.8 4.0 14.2 2.5 8.6 3.6 40.7 5.4 19.6 14.0 6.7 50.7 12.3 10.1 34.9 11.1 2.4 24.8 8.3 23.3 3.2 21.9 47.4 10.0 39.5 22.3 26.3 38.0 50.8 22.2 20.2 11.6 6.5 13.3 6.4 13.2 TXLNA DKFZp451J0118 ENSG00000084652 "Taxilin alpha" P40222 1 32179675-32198285 "Cancer-related genes, Predicted intracellular proteins" Exocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045383, HPA072477" Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Nucleoplasm, Centrosome" "HPA045383: AB_10967649, HPA072477: AB_2686525" "prognostic favorable (6.24e-4)" "unprognostic (1.19e-2)" "unprognostic (3.01e-1)" "unprognostic (1.99e-1)" "unprognostic (5.04e-2)" "prognostic favorable (5.53e-4)" "prognostic unfavorable (1.57e-6)" "unprognostic (3.67e-3)" "unprognostic (2.75e-1)" "unprognostic (5.25e-3)" "prognostic favorable (8.69e-5)" "unprognostic (5.06e-2)" "prognostic unfavorable (7.21e-7)" "unprognostic (3.94e-3)" "unprognostic (3.28e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" 26.1 35.8 20.6 20.7 22.0 16.5 20.3 20.6 21.3 30.7 27.5 32.2 16.9 35.4 22.7 30.7 30.5 18.7 22.2 20.4 22.8 30.0 45.6 23.1 22.0 25.3 23.6 29.0 29.2 32.5 31.7 16.7 22.1 30.1 17.9 12.6 23.2 21.7 21.8 31.3 24.4 27.8 21.5 28.5 26.5 29.4 23.9 19.3 27.0 14.5 27.0 28.6 24.3 22.7 45.1 37.7 38.5 43.5 48.8 63.8 31.1 62.7 49.6 59.3 56.6 42.4 47.4 51.1 24.9 61.2 19.5 49.5 53.0 41.2 53.7 58.8 41.0 80.8 57.6 55.8 51.7 59.4 61.4 64.3 54.2 62.8 29.6 43.6 47.6 60.8 33.5 51.3 49.2 25.0 43.8 38.1 56.1 32.0 34.3 50.8 58.3 45.1 40.6 56.4 40.1 41.3 65.1 40.8 68.5 46.9 37.8 35.6 49.9 62.3 53.5 83.3 81.1 75.8 63.0 45.7 64.5 79.5 58.9 11.0 8.8 4.6 12.9 9.8 11.0 6.8 8.8 9.7 6.9 7.4 7.6 8.3 1.4 14.2 13.3 14.3 7.0 10.6 20.6 22.0 20.6 21.3 20.4 22.8 25.3 23.6 22.1 21.5 23.9 22.7 26.2 22.4 21.4 13.4 13.4 8.8 11.3 14.1 17.1 16.0 26.4 24.6 9.5 11.5 16.8 14.7 39.6 10.8 18.9 15.0 1.9 17.4 14.4 26.9 44.7 23.6 26.3 12.4 9.7 16.4 14.3 27.7 23.9 27.4 13.3 20.2 16.1 32.2 18.2 26.9 9.6 18.1 12.2 11.0 10.0 16.8 23.9 15.9 5.4 7.5 20.9 13.3 10.3 9.5 12.9 22.4 7.2 20.7 19.8 12.4 8.3 12.7 24.1 26.1 13.1 33.6 25.8 34.3 23.8 21.2 12.1 6.8 15.5 23.2 14.7 7.7 TXNL4A "DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD" ENSG00000141759 "Thioredoxin like 4A" P83876 18 79970813-80033949 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, mRNA splicing" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 360.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041324 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" Cytosol "HPA041324: AB_2677410" "unprognostic (7.56e-2)" "unprognostic (1.06e-3)" "unprognostic (5.94e-2)" "unprognostic (2.67e-2)" "unprognostic (6.99e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.45e-1)" "unprognostic (9.39e-2)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (4.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" 61.1 79.1 88.1 39.9 92.5 59.6 52.1 96.0 98.7 37.2 94.9 53.5 32.8 35.7 50.3 69.4 38.1 24.1 88.6 95.0 98.4 87.7 97.1 48.2 53.4 89.4 95.8 32.6 86.0 42.2 95.5 31.6 94.1 53.9 33.2 36.5 55.0 25.3 88.5 59.3 48.0 25.6 93.1 67.8 60.5 88.0 91.6 52.4 51.1 61.3 45.6 46.1 45.5 99.3 98.5 129.3 113.0 108.1 90.3 94.7 99.8 104.3 83.5 138.7 124.9 121.2 68.0 118.8 37.8 100.3 94.1 81.4 137.1 121.5 91.2 139.7 173.7 85.6 196.1 288.7 115.4 247.6 134.1 88.6 105.5 98.7 125.6 87.9 132.4 145.0 76.2 168.0 97.8 177.1 177.0 166.3 88.6 74.3 276.9 106.2 75.7 245.4 137.7 152.7 172.1 125.0 51.6 151.8 200.5 96.9 74.6 145.0 62.9 121.3 149.5 55.7 129.4 74.0 302.3 198.6 113.4 185.7 113.9 10.6 10.3 9.0 14.7 12.7 9.9 15.8 11.8 11.6 14.5 17.6 11.7 14.0 8.2 15.6 13.1 31.3 17.3 6.1 88.1 92.5 96.0 98.7 95.0 98.4 89.4 95.8 94.1 93.1 91.6 99.3 81.0 19.2 42.6 14.0 89.2 87.2 76.9 73.6 64.3 35.7 131.9 139.7 80.3 65.8 62.3 66.2 35.5 107.8 104.8 53.6 360.0 123.4 259.3 98.5 66.0 65.2 56.3 94.1 25.3 125.2 156.9 69.8 71.4 88.1 11.4 84.1 47.2 97.4 126.0 45.4 22.5 88.4 59.0 66.4 76.9 245.5 42.0 89.5 94.3 14.0 87.2 81.5 60.8 21.1 34.8 144.5 54.9 45.1 177.9 177.2 48.6 271.8 41.9 51.3 46.0 61.2 100.8 84.6 74.2 147.6 109.8 96.7 78.7 112.6 71.1 119.4 TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530032 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 643.9;Hofbauer cells: 477.4;Macrophages: 561.7;monocytes: 2174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 135.8;eosinophil: 74.9;intermediate monocyte: 98.4;myeloid DC: 39.5;neutrophil: 114.1;non-classical monocyte: 77.1" "Group enriched" "Detected in all" 10 "dendritic cells: 39.5;granulocytes: 114.1;monocytes: 135.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.0;HHSteC: 95.2;Karpas-707: 68.6;U-266/70: 68.6" "Not detected" "Not detected" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 11000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nuclear bodies, Golgi apparatus" Cytosol "CAB002518: AB_563953, HPA000530: AB_2666017, HPA001072: AB_1080274" "unprognostic (7.02e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "prognostic favorable (4.34e-5)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-1)" "unprognostic (7.17e-2)" "unprognostic (4.64e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (3.50e-8)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" 46.8 19.5 6.1 77.7 6.0 22.0 37.9 7.1 7.9 32.2 12.7 20.4 26.1 7.8 0.5 58.5 30.0 7.2 26.7 6.4 8.6 38.2 82.0 63.4 31.5 22.1 18.3 4.0 13.8 4.5 8.8 15.4 15.9 21.0 3.6 0.0 40.0 5.6 10.7 24.5 32.5 9.1 10.9 86.1 31.2 3.0 18.0 15.6 25.4 1.6 15.3 22.9 27.0 12.2 27.0 2.5 0.4 0.8 1.8 2.2 5.1 3.7 0.5 6.1 17.4 0.1 40.0 1.8 4.1 5.8 1.3 21.0 0.2 1.0 0.0 9.0 16.5 1.8 3.9 3.5 95.2 1.3 26.9 4.7 4.6 5.4 0.0 0.1 0.1 0.5 2.8 68.6 0.9 1.9 1.5 9.9 0.6 1.9 9.1 5.7 0.4 35.1 0.3 1.2 0.7 5.6 22.9 17.3 6.5 0.2 4.2 13.8 6.7 0.8 4.7 1.5 1.5 68.6 15.9 5.7 1.9 1.5 1.6 19.5 135.8 74.9 2.0 98.4 1.2 6.7 2.9 1.2 39.5 6.9 1.6 1.3 114.1 9.5 77.1 9.3 3.1 10.1 6.1 6.0 7.1 7.9 6.4 8.6 22.1 18.3 15.9 10.9 18.0 12.2 122.6 12.8 29.0 0.3 122.9 58.5 57.4 169.9 53.5 3.4 101.5 90.8 3.2 50.1 88.6 33.1 4.2 17.2 65.8 154.8 29.4 340.2 2.2 55.7 56.0 55.7 16.8 19.6 0.3 643.9 300.8 81.9 38.7 59.2 53.4 3.0 38.2 93.0 477.4 0.0 0.4 50.2 24.4 371.8 409.4 8.7 5.0 561.7 113.8 4.7 2174.6 2.9 71.1 0.5 0.2 364.0 86.4 1.9 102.1 109.8 214.5 105.1 78.0 6.6 26.3 93.3 62.4 1.5 8.0 71.7 56.7 33.5 62.5 3.7 51.1 76.0 TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin like peroxisomal matrix peptidase 1" Q2T9J0 10 70137981-70146700 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 120.7;Late spermatids: 227.4;Spermatocytes: 124.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 27.5;PC-3: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" Cytosol "HPA030304: AB_10670560" "unprognostic (4.75e-3)" "unprognostic (4.30e-2)" "unprognostic (2.44e-2)" "unprognostic (7.69e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.02e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.26e-3)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" 5.7 6.0 1.4 1.9 1.3 0.9 5.4 1.7 1.8 5.8 1.1 4.9 3.3 4.1 0.6 11.8 4.5 0.6 2.9 1.0 0.9 5.2 6.4 2.8 1.8 2.1 0.7 4.2 6.2 1.3 3.4 1.3 0.8 5.7 0.6 0.2 5.7 1.5 3.2 11.4 5.0 0.3 0.6 5.4 3.9 14.2 0.9 1.2 4.6 0.5 0.9 4.8 6.5 1.4 16.0 10.2 0.8 6.2 1.0 0.9 3.7 2.2 1.4 2.0 1.8 6.2 9.6 13.8 6.0 0.5 0.6 27.5 1.0 3.9 0.4 8.9 9.5 0.7 2.9 3.3 2.4 1.2 0.1 2.0 7.6 1.7 3.1 1.2 1.4 4.9 0.1 4.3 0.8 6.3 5.3 5.6 3.3 3.5 41.7 8.9 2.6 6.2 0.9 2.6 7.4 3.8 6.7 14.8 6.1 0.2 9.4 1.1 2.6 2.5 1.7 4.8 8.7 14.9 9.9 7.0 2.9 6.2 1.8 0.0 0.8 0.7 3.8 1.2 2.4 3.0 2.2 2.8 0.9 3.3 3.0 2.6 0.3 2.0 0.7 0.7 2.6 1.4 1.4 1.3 1.7 1.8 1.0 0.9 2.1 0.7 0.8 0.6 0.9 1.4 6.1 9.6 5.3 4.9 12.6 14.3 14.5 13.3 14.8 6.9 14.8 16.9 4.2 27.1 7.8 11.0 0.0 35.2 15.5 14.6 17.6 7.8 120.7 5.5 6.8 6.3 14.3 5.0 6.7 9.5 9.8 7.5 5.1 6.3 13.4 9.3 6.8 16.5 12.1 0.0 6.0 12.1 16.2 10.7 6.6 227.4 9.3 8.2 12.4 6.5 6.1 7.0 12.3 11.6 5.5 5.5 11.6 7.9 7.5 14.5 19.2 16.5 3.9 4.4 6.6 6.9 6.1 124.7 12.5 22.4 18.5 16.7 14.0 10.6 21.0 8.8 TYW1 "FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W" ENSG00000198874 "TRNA-yW synthesizing protein 1 homolog" Q9NV66 7 66995173-67239519 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.8;Oligodendrocytes: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: AB_2668852, HPA014118: AB_2668941, HPA015535: AB_1856487, HPA043136: AB_2678333, HPA047029: AB_2679909, HPA047052: AB_2679918, HPA052097: AB_2681723" "unprognostic (1.53e-1)" "unprognostic (5.49e-3)" "unprognostic (1.62e-1)" "unprognostic (3.05e-2)" "unprognostic (1.84e-2)" "unprognostic (2.20e-1)" "unprognostic (1.83e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.86e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-2)" "unprognostic (4.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.36e-2)" "unprognostic (1.79e-2)" 7.7 10.8 5.5 8.1 5.9 9.1 10.0 6.6 7.6 13.0 8.8 9.0 9.5 9.2 9.7 6.6 10.1 7.1 7.9 5.6 6.4 8.8 12.0 7.2 9.8 6.4 5.8 12.2 7.3 13.1 6.9 8.4 6.1 9.8 10.7 9.0 7.1 9.5 15.6 7.9 7.8 9.2 5.6 7.7 7.7 8.1 5.7 10.4 12.8 8.4 9.4 8.5 8.7 7.3 16.3 20.5 12.1 24.9 17.4 12.0 13.8 16.8 12.9 12.9 12.0 23.3 20.2 28.1 25.2 15.4 18.6 18.4 24.9 20.3 18.4 22.1 24.1 11.9 17.1 15.6 17.7 27.7 15.1 12.4 20.3 17.5 27.0 10.6 13.0 20.9 32.3 16.0 15.6 15.7 18.1 23.4 21.1 27.2 18.8 19.7 16.6 34.8 17.4 16.4 18.2 18.3 20.4 38.4 17.6 22.7 26.6 19.6 14.0 15.0 10.8 11.8 23.3 16.1 25.7 33.2 12.1 25.9 20.8 2.4 7.4 3.9 8.5 7.7 11.2 8.3 8.8 9.5 8.8 9.8 10.8 11.7 1.8 11.1 10.0 6.7 6.8 6.2 5.5 5.9 6.6 7.6 5.6 6.4 6.4 5.8 6.1 5.6 5.7 7.3 10.0 6.4 15.3 39.2 18.2 10.5 5.3 10.0 17.1 12.0 11.4 11.7 9.5 10.0 7.6 11.0 4.2 18.6 11.7 7.8 0.0 7.8 7.3 10.9 18.0 8.8 4.8 12.6 57.8 6.9 13.1 11.0 12.8 10.9 34.2 9.1 6.1 14.2 7.7 3.3 53.4 12.3 12.2 7.1 11.2 4.5 8.4 10.3 8.8 43.1 10.0 6.8 10.3 50.3 58.7 7.1 4.0 8.2 18.0 6.2 4.9 2.4 9.6 11.5 19.7 11.2 10.4 23.9 23.4 15.6 16.9 15.2 17.1 10.2 11.4 3.3 TYW1B "LINC00069, MGC87315, NCRNA00069, RSAFD2" ENSG00000277149 "TRNA-yW synthesizing protein 1 homolog B" Q6NUM6 7 72558744-72828200 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.9;Excitatory neurons: 47.4;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 37: B-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: AB_2668852, HPA014118: AB_2668941, HPA043136: AB_2678333, HPA047029: AB_2679909, HPA047052: AB_2679918, HPA052097: AB_2681723" "unprognostic (2.61e-1)" "unprognostic (3.54e-1)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (1.91e-2)" "unprognostic (6.22e-3)" "unprognostic (3.88e-2)" "unprognostic (1.64e-2)" "unprognostic (1.19e-2)" "unprognostic (8.96e-3)" "unprognostic (5.78e-2)" "unprognostic (2.90e-2)" "unprognostic (4.33e-4)" "unprognostic (1.02e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.90e-2)" 2.3 1.8 2.4 1.3 2.3 2.9 2.5 2.0 2.6 4.1 6.9 1.8 1.0 2.4 2.9 2.0 2.3 0.9 1.5 2.5 2.3 1.8 4.5 1.6 1.7 1.8 1.4 5.3 2.0 1.7 2.1 1.8 1.9 2.6 2.4 2.5 1.8 2.7 3.4 2.6 1.7 1.3 1.5 1.9 2.0 2.9 1.8 2.4 3.4 1.1 2.5 2.6 3.1 3.1 2.4 2.5 1.0 2.0 1.5 0.5 1.1 1.2 0.5 1.0 1.1 8.0 4.1 7.4 0.7 0.8 1.0 1.1 1.9 0.8 1.2 8.0 2.3 0.7 1.2 4.7 0.8 7.6 2.0 3.6 0.5 1.2 0.8 0.6 0.7 1.6 10.3 7.5 1.0 1.0 2.5 3.8 1.8 3.1 4.5 1.4 5.4 2.7 1.1 0.8 1.7 0.9 1.5 8.2 4.5 3.1 2.1 2.6 3.1 1.8 4.1 9.4 1.4 6.5 8.4 8.2 0.5 2.1 9.5 3.0 1.9 3.3 1.5 0.8 1.3 4.7 0.9 0.9 0.7 2.3 1.1 1.4 2.2 1.2 0.8 2.9 1.0 0.6 2.4 2.3 2.0 2.6 2.5 2.3 1.8 1.4 1.9 1.5 1.8 3.1 3.5 0.0 2.0 21.9 7.2 0.0 1.8 0.0 2.2 4.3 3.4 3.4 5.3 2.8 0.6 0.0 10.4 4.8 5.4 2.1 0.0 2.9 4.9 3.6 7.6 3.2 0.0 3.2 47.4 0.7 1.7 3.3 4.6 5.3 1.3 2.0 1.8 2.7 3.1 1.7 27.7 2.9 0.0 1.0 0.0 1.1 0.9 3.0 0.0 15.0 3.2 0.9 2.1 23.1 41.4 0.8 2.3 0.7 5.8 2.2 2.0 0.7 1.5 8.0 0.0 6.9 5.2 5.6 5.2 5.4 0.0 1.9 5.1 5.4 2.2 1.1 UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 678.4;U-251 MG: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" 96.0 43.7 12.2 33.7 13.2 51.5 58.8 13.5 14.9 37.1 16.1 65.6 43.9 18.6 29.1 33.9 33.1 39.8 45.1 13.4 13.6 27.0 172.6 36.0 14.1 11.5 16.9 39.9 68.6 12.0 28.9 22.3 11.8 33.3 66.3 20.4 76.6 31.2 41.2 25.0 56.0 24.6 11.6 13.8 55.8 90.9 13.9 11.8 24.4 45.2 22.2 77.9 37.4 11.0 204.6 14.6 39.2 31.5 185.7 147.8 26.8 292.4 107.1 220.7 178.5 38.6 93.5 8.0 64.3 225.8 79.6 35.0 44.7 85.5 359.9 32.4 66.6 36.0 43.8 75.6 87.1 61.8 23.5 69.0 39.8 242.4 678.4 100.6 137.5 62.6 206.1 81.3 298.9 37.4 36.0 40.0 29.2 207.6 64.4 31.9 76.2 99.8 34.8 23.7 41.9 43.4 128.0 78.4 70.4 45.6 38.9 70.0 235.2 110.6 102.5 281.2 463.5 135.0 51.0 67.0 63.4 28.5 71.3 1.4 2.2 11.7 16.7 2.1 20.4 10.7 10.0 17.3 4.6 11.1 9.4 12.0 2.2 8.6 1.2 7.7 5.5 7.2 12.2 13.2 13.5 14.9 13.4 13.6 11.5 16.9 11.8 11.6 13.9 11.0 58.1 6.4 30.2 15.0 42.5 134.7 163.0 47.2 47.8 11.8 59.1 42.7 30.0 27.1 57.4 16.5 8.4 27.2 82.9 94.8 72.4 27.1 78.2 28.6 58.0 35.7 54.9 13.9 12.4 64.7 63.9 195.8 45.9 40.7 33.7 21.3 22.5 98.4 14.5 6.7 12.4 139.4 40.7 10.1 82.2 20.1 50.7 24.6 85.4 3.7 18.2 16.6 41.2 8.0 6.1 73.0 74.5 41.3 152.8 94.6 88.4 26.9 56.0 13.9 19.7 59.4 88.6 212.0 125.9 43.2 81.8 97.7 50.5 18.8 70.4 141.7 UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 383.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: AB_10670578, HPA034874: AB_2674368, HPA065335: AB_2685473" "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (5.56e-3)" "unprognostic (9.26e-2)" "unprognostic (9.35e-3)" "unprognostic (5.53e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.08e-1)" "unprognostic (6.18e-2)" "unprognostic (1.60e-3)" "unprognostic (9.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-3)" "unprognostic (2.61e-3)" "unprognostic (9.24e-2)" "unprognostic (7.80e-3)" "unprognostic (2.52e-1)" 34.3 32.3 83.7 39.4 225.9 39.1 43.4 138.0 136.2 32.1 32.1 34.5 28.8 35.8 41.0 33.9 27.5 29.7 66.6 109.7 198.7 33.9 31.2 32.2 49.6 240.4 162.7 30.0 19.3 45.6 22.9 41.7 245.4 36.6 35.8 62.0 44.9 32.2 41.5 45.0 30.3 39.8 131.0 38.9 26.4 23.7 197.1 44.8 27.1 34.7 49.8 39.4 26.6 383.0 76.6 31.4 75.8 47.1 69.0 90.9 56.1 65.9 74.4 70.4 70.2 39.2 52.2 55.2 18.6 72.5 71.3 42.1 59.1 76.5 80.2 105.0 38.5 77.0 57.7 39.6 53.8 77.1 62.4 72.0 49.8 67.9 54.9 86.7 92.3 45.2 31.9 45.6 94.0 26.8 49.5 49.7 67.5 95.4 26.9 39.6 55.9 53.0 113.2 94.6 32.8 46.2 70.3 51.0 58.4 80.9 34.3 73.3 71.4 53.0 46.9 70.6 93.3 53.2 91.8 67.3 54.5 84.3 69.7 87.9 45.7 71.0 24.3 54.0 28.1 33.6 32.2 30.3 40.1 29.7 29.6 30.5 40.9 39.8 57.1 20.1 40.8 53.0 83.7 225.9 138.0 136.2 109.7 198.7 240.4 162.7 245.4 131.0 197.1 383.0 21.9 35.3 31.4 35.9 35.5 33.8 29.2 66.2 31.9 22.9 21.6 17.9 68.5 14.3 44.5 35.0 39.6 74.5 19.8 15.8 19.6 37.1 15.2 25.1 21.2 26.9 18.6 30.7 44.6 23.6 57.2 28.3 22.4 25.6 42.4 26.0 22.9 17.2 34.1 33.7 62.8 16.3 97.6 37.1 49.6 10.3 40.4 39.6 30.2 44.0 60.6 29.1 24.7 53.3 76.7 31.5 11.7 38.0 28.3 23.7 16.7 36.9 47.3 48.9 26.3 22.2 31.0 34.2 32.1 34.9 42.8 56.8 34.0 24.3 17.5 32.5 UBA52 "CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40" ENSG00000221983 "Ubiquitin A-52 residue ribosomal protein fusion product 1" P62987 19 18571730-18577550 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 11928.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041344, HPA049132, HPA056624" Supported Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Plasma membrane" "HPA041344: AB_2677422, HPA049132: AB_2680646, HPA056624: AB_2683196" "unprognostic (1.98e-2)" "unprognostic (9.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.72e-2)" "unprognostic (5.36e-3)" "unprognostic (9.35e-2)" "unprognostic (1.74e-3)" "unprognostic (4.00e-2)" "unprognostic (7.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.87e-1)" "unprognostic (5.61e-2)" "unprognostic (2.43e-1)" "unprognostic (2.23e-1)" 1161.5 955.0 823.8 793.2 845.7 2181.5 1115.4 815.0 1021.1 1262.7 808.6 984.4 531.1 938.2 966.2 1196.8 984.5 610.9 989.3 803.8 848.5 931.1 927.4 888.7 1469.5 861.9 825.6 1622.0 1664.8 844.0 758.0 720.8 858.2 917.0 789.6 235.6 1061.1 615.4 1629.9 1444.0 916.6 712.9 883.0 1239.2 989.5 755.3 853.4 1487.1 748.6 1196.7 1674.0 995.3 1107.5 875.5 1680.6 1304.1 961.2 1612.8 2437.7 2298.9 2376.3 1260.7 1738.5 2044.2 1618.9 2381.2 1521.6 2403.4 1268.0 2092.8 803.0 1103.3 1881.9 2242.7 1918.7 650.0 2938.0 1320.1 1942.1 2733.4 1770.8 2898.3 1616.2 2684.2 3008.4 1406.4 2024.7 1778.7 2083.2 1508.8 2131.5 3231.7 1769.8 2786.9 2336.4 2584.2 2162.6 3166.1 2800.9 1899.3 958.6 2769.6 2001.7 2497.0 1246.1 1505.9 914.3 2187.0 2300.9 1424.6 970.6 3681.4 1562.7 1017.6 850.0 2172.8 2271.9 1973.0 2863.7 2412.2 1386.0 3245.8 1412.8 962.6 2155.2 1163.1 1761.2 1764.2 2401.7 3126.7 2616.4 2119.8 2320.3 3025.4 2946.4 2445.0 1168.8 1864.5 1629.2 2469.2 2250.9 4829.5 823.8 845.7 815.0 1021.1 803.8 848.5 861.9 825.6 858.2 883.0 853.4 875.5 831.5 464.8 673.1 15.0 2198.0 1898.4 2027.9 1544.8 1365.8 117.9 1444.5 1279.9 332.3 1109.5 886.1 654.7 68.8 2020.5 1806.7 1264.6 1571.0 1437.7 3146.5 772.1 1337.9 1108.6 1106.6 2241.7 10.8 2271.5 2803.3 1060.1 672.2 1194.9 805.8 1061.9 1385.3 1919.9 2574.7 104.3 12.4 1812.7 710.1 3200.4 2894.6 11928.8 1875.2 2003.3 1250.4 8.4 3379.8 599.1 2276.1 11.1 23.1 1799.4 1853.6 1034.7 1202.4 2110.3 1645.1 2688.2 510.4 219.1 696.8 1483.1 2041.1 629.9 674.5 1939.2 2239.4 2282.9 1892.0 1285.6 1783.6 2426.6 UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805209-49813953 "Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 52.5;granulocytes: 83.0;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 56.7;HEL: 55.7;HMC-1: 103.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 370000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: AB_2683631" "prognostic favorable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.48e-4)" 21.6 21.4 10.1 32.7 10.6 40.2 20.7 10.4 12.1 25.6 10.4 29.0 43.4 22.5 15.6 18.7 23.8 27.7 17.9 9.8 10.5 25.6 23.0 35.4 51.2 13.7 11.1 32.8 17.2 2.9 14.1 19.4 12.1 34.8 26.1 1.2 42.3 22.4 9.1 20.5 48.6 20.6 12.3 65.6 27.5 5.8 12.2 39.8 31.8 10.3 33.6 23.1 23.3 13.8 11.6 0.1 0.9 0.3 30.2 31.7 3.5 6.1 27.0 42.7 56.7 0.0 23.9 0.4 4.8 22.4 18.3 6.2 0.1 10.9 3.7 29.9 0.1 55.7 0.6 3.5 22.3 5.3 103.7 49.0 0.7 16.9 1.0 29.6 21.7 2.0 0.1 3.4 10.0 0.3 11.6 13.7 0.1 0.0 1.2 14.6 1.0 1.9 8.8 22.3 0.0 0.9 7.4 10.7 3.8 0.6 1.1 36.8 9.7 8.3 1.1 3.7 2.4 0.1 0.2 0.3 23.2 19.8 2.0 20.7 22.5 38.5 16.4 32.9 14.3 17.1 15.0 14.5 21.3 18.1 13.4 12.4 6.8 17.1 27.6 7.6 15.9 22.0 10.1 10.6 10.4 12.1 9.8 10.5 13.7 11.1 12.1 12.3 12.2 13.8 17.3 32.1 20.3 11.4 28.0 3.8 6.3 10.5 6.8 0.2 9.2 9.1 6.9 17.2 16.6 12.9 0.0 5.2 15.5 28.7 0.0 9.5 6.9 5.8 3.0 13.5 9.5 8.0 0.2 7.8 3.5 11.8 52.5 6.5 83.0 13.2 16.1 7.6 21.6 0.0 0.1 21.7 8.2 20.1 6.4 34.1 11.1 32.5 0.0 15.0 16.8 2.4 19.6 1.0 0.1 5.2 21.7 11.3 14.1 4.4 51.8 5.6 12.8 1.2 6.6 5.8 8.1 0.9 0.3 7.3 4.7 2.9 17.7 6.9 20.2 6.6 UBAC1 "GBDR1, KPC2, UBADC1" ENSG00000130560 "UBA domain containing 1" Q9BSL1 9 135932969-135961373 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 301.3;tongue: 171.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 290.9;Late spermatids: 197.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 246.4;K-562: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005651 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 87000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA005651: AB_1858489" "unprognostic (8.41e-2)" "prognostic favorable (4.34e-6)" "unprognostic (2.10e-1)" "unprognostic (9.15e-2)" "unprognostic (4.11e-1)" "unprognostic (3.85e-2)" "unprognostic (7.68e-3)" "unprognostic (2.85e-1)" "unprognostic (4.37e-2)" "unprognostic (3.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.58e-7)" "unprognostic (1.95e-3)" "unprognostic (9.46e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" 23.1 20.7 42.2 14.7 44.8 82.5 20.7 43.0 43.0 23.8 41.4 38.6 24.3 22.0 12.9 37.4 22.8 12.0 72.0 40.4 42.2 23.5 24.9 19.8 15.7 43.2 42.7 20.9 17.1 27.1 23.5 22.8 41.8 24.7 18.4 15.2 27.8 20.6 301.3 53.2 23.3 16.3 43.7 21.0 23.0 43.1 44.0 17.7 18.0 171.0 16.5 28.3 27.0 41.0 37.4 42.7 29.7 43.4 22.0 25.6 55.7 32.0 27.1 38.9 31.2 59.7 46.3 44.8 30.1 26.4 46.1 124.4 41.9 37.0 17.5 246.4 39.6 37.4 79.0 33.8 22.9 49.2 34.4 24.2 47.7 24.6 23.8 26.0 32.8 41.4 316.6 35.5 31.2 76.9 40.4 50.5 70.5 87.4 71.8 45.1 55.8 59.3 28.0 23.7 46.0 50.6 46.3 41.4 33.5 26.3 34.9 52.5 26.8 22.0 33.0 26.5 40.2 20.5 41.1 53.9 40.7 43.9 30.6 6.5 17.6 8.7 4.8 28.4 5.1 4.9 5.4 3.2 15.6 2.8 2.8 3.3 3.7 4.0 33.4 1.6 4.5 7.0 42.2 44.8 43.0 43.0 40.4 42.2 43.2 42.7 41.8 43.7 44.0 41.0 42.8 16.0 10.0 18.6 14.5 40.7 38.8 41.8 43.3 38.3 29.6 36.2 85.7 11.5 24.5 27.6 31.3 148.6 20.7 45.5 93.9 16.3 101.6 82.9 33.7 27.5 16.8 290.9 17.3 22.9 32.7 22.5 21.9 21.3 7.0 28.6 20.3 32.7 75.2 13.5 23.6 37.4 28.5 34.3 30.3 197.4 19.6 41.8 35.6 9.4 46.0 60.7 13.4 9.0 14.1 22.6 42.3 22.6 24.6 23.1 47.9 35.6 96.0 44.1 19.7 42.8 27.4 57.7 54.9 73.2 64.8 60.5 16.5 25.7 55.6 39.4 UBALD1 FAM100A ENSG00000153443 "UBA like domain containing 1" Q8TB05 16 4608883-4615027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 110.3;Late spermatids: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066771 Approved Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA066771: AB_2685717" "unprognostic (7.09e-2)" "unprognostic (2.21e-2)" "unprognostic (1.55e-1)" "unprognostic (7.67e-3)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.54e-1)" "unprognostic (4.37e-3)" "unprognostic (2.63e-3)" "unprognostic (8.06e-2)" "unprognostic (1.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.99e-2)" "unprognostic (6.20e-2)" "unprognostic (1.35e-2)" 25.5 28.4 21.7 11.1 20.0 26.2 24.6 23.9 39.5 29.9 7.4 44.3 14.2 38.6 2.6 32.8 32.0 6.2 39.8 23.3 16.4 39.2 70.6 29.9 8.7 16.2 14.2 29.2 30.1 5.1 25.0 10.6 14.5 39.6 2.3 4.8 23.7 9.5 51.1 31.4 25.5 6.8 10.6 29.3 34.9 29.1 16.8 5.5 35.4 8.6 4.4 33.5 27.5 24.2 13.5 38.2 8.9 14.2 6.0 7.6 39.4 19.7 8.2 7.6 11.0 18.6 15.5 19.8 21.6 6.3 5.7 36.5 5.7 20.4 2.1 42.4 57.4 18.7 42.8 29.6 12.1 11.8 30.8 10.8 14.9 11.6 5.7 8.7 8.3 15.0 28.7 20.4 3.0 66.0 19.5 63.6 33.3 12.0 33.4 27.9 11.1 65.6 6.7 19.0 25.7 23.7 23.5 35.9 33.1 5.1 23.2 18.9 24.4 15.2 17.2 61.5 13.0 38.8 34.2 22.9 6.2 15.8 8.1 0.9 1.6 8.7 1.6 2.5 1.0 1.3 1.3 1.7 1.9 1.2 1.3 1.4 2.7 1.1 3.3 1.2 1.7 1.3 21.7 20.0 23.9 39.5 23.3 16.4 16.2 14.2 14.5 10.6 16.8 24.2 12.0 9.6 8.2 3.3 14.3 110.3 55.8 32.7 29.6 9.7 23.7 20.6 4.2 15.7 17.9 18.4 4.2 65.8 15.1 26.4 31.3 21.1 37.6 29.1 16.2 16.8 84.6 26.1 6.2 23.6 60.1 16.2 43.3 28.7 10.8 13.6 16.1 32.4 23.6 10.1 6.1 34.4 28.5 14.7 25.9 129.1 16.1 14.5 21.4 1.9 19.4 13.0 23.7 3.5 8.1 22.4 19.0 19.9 22.2 37.6 24.4 57.0 7.3 11.5 46.0 15.2 25.1 18.6 14.6 20.2 102.9 107.8 15.9 14.0 22.0 33.1 UBAP1 UBAP ENSG00000165006 "Ubiquitin associated protein 1" Q9NZ09 9 34179005-34252523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019804 Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Vesicles, Plasma membrane" "HPA019804: AB_1858494" "unprognostic (1.83e-1)" "unprognostic (4.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.54e-1)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-1)" "unprognostic (2.01e-2)" "unprognostic (6.53e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "prognostic favorable (7.49e-6)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" 40.7 55.5 46.4 24.5 47.1 131.5 35.8 48.0 53.4 45.0 46.4 38.5 22.3 34.0 25.5 69.7 33.9 30.4 38.2 45.6 48.2 34.8 53.1 42.5 23.8 48.5 48.5 40.9 28.0 34.4 25.6 29.3 49.4 30.4 24.8 44.8 29.6 30.6 110.0 39.5 26.3 35.2 46.3 28.2 33.6 47.8 49.9 31.6 25.6 71.7 32.7 38.0 45.8 48.2 56.7 31.7 35.2 38.4 63.6 39.3 29.8 44.4 61.6 48.4 65.6 34.3 23.0 39.3 19.5 66.5 41.1 28.3 49.2 69.5 46.4 57.1 22.3 35.1 65.4 35.5 57.8 39.3 44.8 48.7 113.0 57.5 75.0 73.4 54.4 37.9 27.4 38.0 45.7 23.7 36.5 55.0 38.2 38.8 45.9 32.6 24.8 22.8 104.2 36.9 19.9 28.1 49.0 50.2 22.5 31.1 24.6 38.5 39.2 24.7 38.0 37.4 41.5 18.9 25.3 41.0 49.5 31.5 74.2 26.8 50.9 66.6 38.0 45.2 65.8 26.8 38.1 40.0 47.1 23.2 36.3 29.8 120.2 50.1 41.0 26.7 52.9 55.0 46.4 47.1 48.0 53.4 45.6 48.2 48.5 48.5 49.4 46.3 49.9 48.2 21.6 67.3 26.0 44.4 22.4 46.9 66.3 20.4 45.5 15.8 27.9 23.1 13.1 20.0 33.5 7.3 25.0 33.2 21.6 25.8 19.6 34.8 77.5 56.9 37.2 21.4 16.1 50.7 33.1 40.1 35.4 31.2 44.4 90.0 25.9 15.4 17.5 25.3 22.0 6.7 42.9 18.5 30.5 21.4 39.8 62.9 29.2 38.2 24.9 26.2 23.1 26.0 13.4 38.7 35.4 44.3 23.0 42.5 25.0 47.9 22.5 21.0 22.5 10.9 19.7 44.0 32.5 51.0 22.9 54.6 59.0 89.6 28.6 20.8 18.8 70.9 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0;lymphoid tissue: 15.6;placenta: 13.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.9;Inhibitory neurons: 166.3;Langerhans cells: 51.2;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 122.2;HMC-1: 88.9;hTEC/SVTERT24-B: 72.9;REH: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 23000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: AB_10669648, HPA038606: , HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 3.4 0.7 1.1 4.8 1.5 6.7 1.1 15.0 1.9 3.0 0.1 1.2 1.3 1.0 0.2 1.1 0.5 1.9 0.9 1.2 5.5 1.7 1.3 4.6 5.7 10.3 7.1 0.2 0.6 0.4 0.3 13.8 10.2 0.7 1.4 1.9 0.7 0.7 1.1 3.4 1.7 1.9 1.2 15.6 1.4 1.2 2.8 15.1 2.3 0.3 3.2 4.4 0.5 1.4 13.1 31.5 5.6 7.5 2.4 4.4 29.1 45.6 25.1 18.1 13.9 12.5 6.8 5.3 3.5 24.3 17.2 6.4 0.1 16.3 28.7 0.2 0.9 122.2 1.0 10.8 6.7 15.0 88.9 3.9 1.0 72.9 26.9 19.7 12.4 5.3 0.1 0.1 17.8 0.5 18.5 9.6 2.5 13.3 7.4 73.3 3.3 0.7 28.6 10.9 12.7 0.2 12.1 0.9 10.1 11.7 0.2 4.0 32.3 23.4 12.6 13.9 19.1 1.0 0.0 15.1 12.4 20.6 43.4 0.0 1.3 9.9 1.8 6.3 1.9 0.3 2.3 1.7 1.7 1.1 2.6 1.4 2.7 6.4 11.1 0.2 4.7 1.8 1.1 1.5 15.0 1.9 1.2 5.5 10.3 7.1 10.2 1.2 2.8 1.4 2.2 0.0 4.7 9.1 4.6 7.1 4.2 3.4 2.8 1.8 1.2 1.3 1.1 0.0 2.0 3.7 0.0 32.5 10.0 0.6 0.0 8.4 2.4 0.6 4.0 4.5 0.0 1.7 24.8 9.7 54.9 4.9 2.0 1.5 12.7 11.5 5.0 0.6 35.7 11.8 166.3 0.5 4.1 26.0 51.2 3.9 0.0 26.5 1.8 30.0 9.1 0.2 17.5 26.2 2.7 26.3 0.3 0.4 11.4 4.7 0.2 0.6 2.5 1.1 0.0 3.8 3.4 0.1 0.8 2.4 6.0 47.6 16.8 0.1 0.4 3.1 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558954 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 1197.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No 49000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: AB_436983, HPA054551: AB_2682520, HPA057800: AB_2683531" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-3)" "unprognostic (3.90e-3)" "unprognostic (4.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (8.63e-3)" "unprognostic (1.76e-1)" "unprognostic (5.85e-2)" "unprognostic (8.42e-3)" 46.3 66.1 133.2 39.2 138.8 82.2 42.8 116.7 199.7 48.9 104.0 72.5 41.7 48.1 36.3 61.8 51.3 30.9 111.0 141.2 129.3 63.2 45.6 46.3 43.4 123.5 124.4 46.0 47.5 84.5 69.7 45.0 127.7 48.3 32.5 49.7 48.5 46.1 174.0 56.6 41.6 39.5 111.9 49.3 55.8 81.0 124.4 51.7 44.3 104.5 43.7 58.3 45.8 139.1 161.8 272.1 119.3 124.8 61.7 71.9 112.2 166.0 117.4 97.8 82.8 162.7 109.7 161.9 135.5 93.4 198.1 105.9 130.1 138.6 69.2 207.3 1197.4 235.5 163.7 113.7 154.4 197.3 192.9 82.1 107.1 145.9 167.3 102.6 117.8 146.3 119.6 179.4 127.3 158.2 177.2 223.7 87.1 155.1 306.5 171.7 106.7 204.5 111.6 166.8 239.5 205.5 133.1 149.7 163.3 41.6 94.4 188.4 105.2 333.4 80.5 110.6 281.3 262.3 411.9 169.6 206.0 177.6 220.5 6.7 3.6 4.2 3.0 2.6 2.2 2.8 3.2 3.2 2.8 3.8 3.3 2.2 10.1 1.7 2.7 6.7 2.9 1.9 133.2 138.8 116.7 199.7 141.2 129.3 123.5 124.4 127.7 111.9 124.4 139.1 75.1 6.4 13.0 14.7 32.7 40.4 36.3 15.9 6.2 100.0 74.5 81.3 38.5 20.0 11.6 18.4 20.9 21.0 72.9 63.9 7.9 17.3 25.7 89.6 68.0 40.1 41.2 39.8 22.9 30.6 22.4 38.9 21.9 63.3 19.7 103.3 28.5 38.0 35.4 109.4 20.8 43.8 20.3 27.0 33.5 34.0 17.4 42.5 35.6 15.9 21.1 142.3 14.4 8.5 17.9 41.8 21.4 13.9 35.4 59.1 37.9 33.9 18.6 81.1 26.3 41.5 55.4 27.1 7.9 17.0 56.8 52.5 41.0 156.1 41.6 56.2 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Centrosome, Cytosol" "HPA063368: AB_2684996" "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavorable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favorable (1.86e-5)" "unprognostic (1.04e-2)" 25.4 23.1 36.1 19.0 37.0 32.2 22.4 34.5 43.3 21.2 35.2 24.3 18.7 21.8 27.2 27.4 23.7 19.9 25.9 37.3 38.0 28.8 31.6 25.0 29.5 36.0 36.0 23.1 31.8 28.3 31.3 23.9 37.5 21.2 28.2 25.9 22.5 20.9 26.3 26.7 25.5 24.4 35.5 32.3 26.8 34.6 38.2 29.8 23.0 25.8 35.2 25.7 22.2 36.2 39.0 33.0 45.6 35.0 45.8 46.9 39.4 38.0 57.0 47.3 38.0 37.3 40.4 47.5 53.3 52.8 39.5 33.0 54.3 43.6 40.5 48.7 34.3 37.8 29.6 36.4 57.5 62.1 58.3 45.5 56.7 38.5 44.1 51.3 61.8 43.3 32.4 57.1 61.3 60.4 38.1 45.6 62.5 92.3 55.5 43.4 31.8 50.3 52.4 40.6 46.2 64.6 38.1 70.6 64.5 77.5 43.3 93.2 43.3 30.5 34.1 36.5 41.2 69.3 55.2 62.1 34.2 43.2 47.1 3.9 1.3 2.9 2.1 1.6 2.0 1.4 2.0 2.7 1.2 1.5 2.2 2.5 2.0 2.3 1.3 2.4 3.1 0.8 36.1 37.0 34.5 43.3 37.3 38.0 36.0 36.0 37.5 35.5 38.2 36.2 40.8 32.1 26.5 9.8 24.7 16.2 18.0 15.9 15.4 41.2 27.3 32.5 29.4 27.1 18.4 16.5 4.2 19.8 45.2 33.4 11.7 14.5 4.5 24.8 20.9 32.8 33.6 12.0 12.2 21.0 18.2 23.3 14.3 24.9 10.8 31.9 35.3 38.3 27.5 60.6 11.7 29.2 22.4 48.0 19.7 7.3 17.7 27.9 14.2 10.3 30.9 42.8 39.1 7.1 11.7 26.2 18.5 19.2 22.1 29.5 29.6 19.7 29.0 23.1 13.1 20.1 21.2 34.1 29.2 18.1 19.0 19.6 26.5 36.3 25.7 31.4 UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817160-33920399 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061000, HPA074334" Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA061000: AB_2684408, HPA074334: " "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.53e-1)" "unprognostic (6.55e-2)" "unprognostic (5.15e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.82e-3)" "unprognostic (4.61e-3)" "unprognostic (3.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.19e-1)" "unprognostic (2.01e-2)" "unprognostic (4.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.43e-1)" 32.0 20.6 25.4 20.2 27.3 15.4 27.1 24.8 28.0 30.8 20.8 31.4 28.0 28.5 16.3 29.2 23.9 18.6 32.4 24.8 24.6 22.1 33.3 28.2 21.7 27.2 25.8 30.1 53.4 14.5 15.0 23.9 26.7 20.9 19.6 25.0 21.5 18.4 63.1 34.5 24.8 25.9 24.5 23.1 22.1 44.8 25.0 30.1 18.3 44.8 25.4 26.6 28.7 30.2 41.2 42.0 78.7 35.0 42.0 68.2 25.1 34.7 46.5 38.7 38.3 34.0 28.7 33.9 14.4 47.2 28.3 17.8 41.5 38.5 41.8 58.3 22.7 28.7 43.7 43.3 60.1 34.6 31.0 58.4 55.6 31.8 59.2 61.5 65.8 39.8 28.0 35.0 38.7 22.6 68.0 91.4 46.2 33.1 34.7 63.2 24.0 17.6 41.1 28.9 37.6 45.4 40.1 35.2 27.0 49.5 31.3 41.9 50.3 37.8 35.4 26.8 32.9 23.5 23.0 46.5 36.0 19.7 83.5 22.6 10.9 6.3 2.8 11.1 1.7 4.6 2.6 2.2 6.1 4.8 2.5 2.3 31.7 7.4 18.7 3.7 3.3 4.0 25.4 27.3 24.8 28.0 24.8 24.6 27.2 25.8 26.7 24.5 25.0 30.2 73.7 22.4 30.7 39.8 38.6 105.5 46.3 26.1 32.5 65.8 57.8 60.8 134.8 57.2 26.8 22.0 14.6 69.5 46.4 64.7 15.6 49.7 311.1 65.7 84.9 74.9 72.0 36.6 67.8 69.4 82.0 57.4 25.5 81.8 13.3 99.2 84.9 88.3 76.6 60.6 67.0 55.4 32.6 123.5 112.2 257.4 67.1 110.6 35.6 40.3 116.4 124.3 42.2 45.2 127.8 84.7 49.1 76.0 24.0 83.9 79.1 59.8 25.0 31.2 59.2 48.3 55.6 94.4 64.6 41.8 120.5 82.8 34.9 68.0 48.7 121.2 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138916-157269370 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favorable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 25.7 17.4 12.0 21.5 13.2 16.2 21.7 17.5 14.1 18.4 18.8 22.3 20.0 19.4 13.4 28.3 18.5 19.1 28.5 13.2 14.1 20.3 22.9 19.0 20.9 14.6 13.4 20.0 22.4 36.2 11.1 17.5 14.9 19.9 23.2 20.2 22.7 22.7 65.6 20.8 20.8 29.2 12.7 18.0 20.9 26.2 14.8 18.6 17.3 58.5 22.8 28.1 17.0 15.0 68.8 53.3 33.5 67.3 58.8 61.3 37.1 74.0 63.4 61.1 61.3 48.3 55.7 36.8 64.0 82.1 79.6 42.4 52.6 68.3 72.0 67.6 48.3 37.6 35.6 35.0 58.4 56.9 52.8 54.8 61.6 68.0 55.9 46.4 72.2 30.3 55.7 39.9 87.6 59.8 56.2 35.9 53.3 61.1 63.6 31.9 37.7 75.9 63.2 74.1 53.5 55.2 72.8 61.9 54.5 37.2 32.0 39.3 65.3 76.6 16.5 190.0 93.3 39.7 42.9 37.0 87.7 83.0 89.5 0.3 1.8 1.1 2.2 2.3 3.0 1.1 2.4 2.4 2.0 1.2 2.2 2.7 0.6 2.1 2.5 1.8 2.8 1.5 12.0 13.2 17.5 14.1 13.2 14.1 14.6 13.4 14.9 12.7 14.8 15.0 23.8 22.4 19.7 52.2 14.2 27.5 17.3 19.0 17.6 34.7 22.4 16.9 33.7 22.8 14.2 25.8 66.7 14.9 25.3 27.3 9.8 20.3 11.6 21.6 27.4 23.4 24.5 14.9 98.9 17.7 17.4 19.6 27.0 24.5 9.5 23.0 23.6 48.3 15.4 32.0 100.7 21.8 12.2 27.6 15.2 10.1 15.5 20.6 5.4 52.5 22.0 9.9 26.8 81.4 96.2 27.5 13.4 25.6 17.5 31.5 20.6 19.1 19.8 39.9 0.0 23.1 21.4 26.6 27.3 37.5 33.2 15.1 20.9 22.3 26.2 28.1 UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263290-159286036 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA039615: AB_10674425" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "unprognostic (6.04e-3)" "unprognostic (3.45e-2)" "unprognostic (7.08e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (4.46e-5)" "unprognostic (4.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (2.51e-2)" 19.0 16.3 8.8 24.5 9.4 23.3 20.5 9.6 14.1 19.9 6.4 15.7 12.6 23.6 17.2 21.1 15.1 17.1 16.4 10.0 10.5 19.2 18.3 22.4 33.7 10.3 9.5 15.8 14.9 19.7 5.6 23.6 10.2 17.5 16.9 18.2 14.2 19.6 10.9 15.5 12.7 22.8 9.6 26.7 15.8 30.5 10.7 36.4 16.6 13.8 37.3 21.3 11.7 10.7 39.9 28.6 57.9 64.1 58.9 54.5 34.1 42.5 64.6 42.8 56.6 23.5 27.1 35.7 46.1 53.7 60.9 29.7 36.3 81.8 74.3 71.3 35.7 27.3 23.8 21.9 74.0 62.7 41.1 48.1 76.8 38.9 77.2 34.0 41.4 36.4 38.4 47.0 60.8 12.9 33.5 22.9 41.7 20.0 17.1 42.3 56.5 42.8 44.4 30.4 30.4 42.9 42.7 29.0 115.8 34.6 30.2 45.6 44.2 44.0 37.8 22.8 54.9 36.9 39.8 53.5 46.1 43.9 66.1 47.6 10.8 27.5 25.5 22.4 28.4 18.5 23.9 26.7 14.2 16.7 26.9 29.1 30.8 42.8 24.5 17.8 28.3 13.6 8.8 9.4 9.6 14.1 10.0 10.5 10.3 9.5 10.2 9.6 10.7 10.7 31.9 12.8 41.6 12.7 43.0 15.9 10.3 43.0 35.3 12.7 22.5 14.4 16.8 10.0 34.4 14.7 4.2 31.8 36.8 13.2 35.2 23.0 8.5 23.2 32.1 24.2 10.7 30.1 26.3 24.9 18.7 27.1 29.6 17.4 45.0 16.9 28.5 15.6 39.0 20.2 25.0 14.6 18.3 40.0 16.4 4.2 20.5 33.1 17.8 14.0 30.9 17.6 32.0 22.6 25.6 22.5 10.1 24.8 39.3 13.2 8.8 34.5 37.4 13.1 19.7 18.8 26.2 74.0 61.5 51.8 20.6 17.8 40.8 30.7 14.5 10.1 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.9;Inhibitory neurons: 108.8;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038838, HPA038839" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA038838: AB_10673120, HPA038839: " "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 9.1 7.9 12.5 8.8 29.4 24.9 9.3 11.7 17.4 9.9 4.8 8.6 7.8 10.7 7.4 5.8 8.0 8.6 13.7 11.6 31.5 9.2 7.1 8.6 10.9 24.2 18.3 7.7 9.5 14.3 6.6 10.5 21.6 10.0 8.0 14.3 6.3 10.5 12.0 5.6 7.8 9.6 8.5 9.5 7.2 10.1 21.2 13.3 12.6 14.0 8.7 9.1 5.8 48.6 7.4 10.2 11.6 9.6 17.1 14.7 10.7 17.6 19.4 15.9 19.2 13.3 5.5 8.6 10.1 18.4 18.9 12.4 17.1 15.5 18.1 18.0 8.4 33.1 20.4 6.3 12.3 23.0 14.4 15.3 8.4 18.8 14.8 14.6 17.0 16.7 19.6 12.3 18.7 4.5 12.7 6.8 6.5 18.9 10.6 16.4 15.7 6.4 14.9 16.6 12.0 10.3 22.7 12.0 7.7 13.1 10.9 12.2 24.3 17.9 11.1 16.7 18.0 14.6 26.4 23.6 12.2 14.6 16.6 3.7 1.5 2.5 2.4 1.8 2.9 1.9 2.6 2.9 1.4 2.3 2.6 3.2 2.9 3.2 1.7 2.2 1.9 0.9 12.5 29.4 11.7 17.4 11.6 31.5 24.2 18.3 21.6 8.5 21.2 48.6 46.4 48.1 30.7 73.1 28.9 10.6 11.6 9.3 17.1 27.5 15.4 10.8 28.0 12.8 19.1 9.2 27.1 14.7 35.8 12.8 0.0 10.8 16.8 13.4 27.4 24.5 14.4 23.8 108.9 14.4 7.7 25.6 20.9 18.2 28.5 22.8 17.2 9.9 8.1 32.0 108.8 10.9 14.2 16.4 10.6 16.9 16.1 17.1 8.8 73.1 15.6 13.5 23.7 102.1 127.6 10.3 8.2 20.7 33.2 7.7 12.3 9.2 15.7 38.8 13.1 34.7 36.5 27.0 17.8 8.6 7.2 36.9 31.4 16.5 10.6 9.8 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 271.0;Suprabasal keratinocytes: 252.9;Urothelial cells: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 56.2 62.8 48.2 23.0 46.0 79.8 49.8 38.7 48.4 57.4 47.6 69.6 20.9 61.7 35.7 55.4 52.3 29.6 58.7 45.8 46.0 74.7 82.7 71.9 25.7 51.5 46.4 75.3 53.5 35.5 70.7 27.5 54.9 67.2 22.7 44.6 48.0 27.0 129.1 161.9 59.7 26.0 35.2 62.8 70.6 105.3 45.9 34.6 56.5 45.0 25.7 90.0 59.2 44.7 61.4 60.7 53.5 39.7 97.6 50.0 46.2 46.5 48.8 49.5 44.7 97.2 51.3 36.6 42.3 61.7 43.3 40.8 42.3 46.3 46.0 30.6 37.5 83.8 63.3 64.1 68.6 51.9 53.4 45.0 57.9 100.8 96.3 48.1 54.9 63.7 58.5 32.9 47.6 43.6 24.7 62.9 43.5 124.3 33.6 34.0 41.7 31.0 44.7 35.2 37.7 37.4 55.0 31.1 39.9 48.6 21.7 40.4 85.9 57.4 36.1 69.0 52.8 38.8 25.2 41.5 39.3 79.3 50.3 39.8 28.7 4.7 4.9 5.9 4.2 7.4 4.4 2.9 14.2 4.0 3.9 3.7 15.4 4.4 2.1 6.5 3.4 8.3 48.2 46.0 38.7 48.4 45.8 46.0 51.5 46.4 54.9 35.2 45.9 44.7 28.1 35.3 37.6 85.5 30.3 271.0 124.6 28.9 28.5 57.5 22.1 23.9 19.1 37.1 30.4 31.3 152.2 24.7 34.2 31.6 13.7 41.3 21.4 39.8 32.0 30.8 17.5 48.4 58.9 40.9 17.0 32.2 44.9 50.4 19.6 32.9 31.1 94.1 63.2 79.1 61.8 29.2 12.2 43.0 48.7 28.7 30.7 46.4 49.8 34.7 64.4 28.8 21.6 51.8 44.5 61.0 16.7 35.7 26.4 59.1 57.9 135.6 39.1 48.5 19.7 28.3 30.1 44.8 21.0 28.0 252.9 33.9 32.7 34.5 20.1 236.5 UBTD1 FLJ11807 ENSG00000165886 "Ubiquitin domain containing 1" Q9HAC8 10 97498924-97571206 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.4;neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034825 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane, Cytosol" "HPA034825: AB_10602254" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (2.43e-1)" "unprognostic (1.78e-1)" "unprognostic (3.90e-2)" "unprognostic (3.63e-3)" "unprognostic (1.43e-2)" "unprognostic (1.66e-3)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "unprognostic (4.78e-1)" "unprognostic (6.62e-3)" "unprognostic (8.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-3)" "unprognostic (3.50e-3)" 18.8 11.1 14.9 5.7 15.2 8.8 14.7 16.8 17.0 16.5 12.6 10.3 1.8 13.5 4.0 9.5 13.6 7.0 35.1 13.5 15.8 29.2 18.6 29.8 3.1 17.7 17.1 8.7 9.6 3.6 15.9 3.8 16.2 13.4 0.6 6.0 11.2 7.5 34.2 49.5 5.5 3.6 16.1 11.0 9.4 60.3 18.9 1.6 14.6 11.2 1.1 12.4 16.3 14.6 18.1 17.7 4.6 23.0 18.9 17.8 5.4 20.3 29.4 21.3 16.3 12.0 15.4 2.2 24.1 13.8 13.4 21.4 4.6 27.2 3.0 5.6 9.1 2.2 5.5 15.2 27.2 2.0 5.9 24.6 9.0 23.3 5.7 32.8 34.3 4.7 1.2 3.3 13.9 8.6 0.9 18.5 7.5 3.4 32.1 1.8 8.1 2.1 16.7 6.7 1.5 4.8 9.2 5.6 27.1 4.0 20.8 13.6 37.5 26.9 16.4 28.4 26.8 4.2 5.1 0.9 22.7 12.3 14.3 1.0 2.6 6.4 0.1 0.7 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.6 0.0 0.7 0.9 0.3 0.5 14.9 15.2 16.8 17.0 13.5 15.8 17.7 17.1 16.2 16.1 18.9 14.6 5.0 41.7 28.6 13.1 1.1 26.0 8.8 32.2 19.4 3.8 10.0 4.8 15.5 8.6 21.2 7.3 4.2 3.5 0.6 1.5 11.7 18.9 53.5 8.2 8.7 23.8 0.0 0.4 5.6 12.8 12.8 11.6 2.6 4.0 0.0 0.8 7.9 7.0 25.8 6.7 5.9 0.2 10.2 10.1 18.9 33.8 12.8 10.3 10.6 12.2 8.4 16.5 2.1 2.0 14.5 22.1 0.1 9.4 3.0 14.0 0.0 10.4 19.1 18.6 13.1 8.5 10.3 7.5 7.9 8.2 29.7 2.9 1.9 1.5 0.4 7.6 UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 79.9" "Group enriched" "Detected in many" 5 "Early spermatids: 167.4;Granulosa cells: 191.2;Hepatocytes: 65.7;Late spermatids: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: AB_1847462, HPA077538: AB_2686844" "unprognostic (3.00e-2)" "unprognostic (2.30e-1)" "prognostic favorable (6.13e-4)" "unprognostic (7.71e-2)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (5.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" 10.2 17.3 17.0 7.1 12.0 8.8 14.1 12.2 16.1 10.4 0.0 12.5 13.1 10.4 49.9 10.7 13.2 13.5 4.9 13.3 5.4 22.1 44.1 8.7 8.1 10.3 4.2 79.9 33.0 20.5 2.8 15.6 10.6 16.3 16.3 11.6 8.5 18.6 3.7 16.9 12.1 10.8 1.7 11.1 12.4 37.1 9.2 14.3 25.9 5.4 9.7 10.4 3.3 12.7 16.4 17.0 11.7 12.2 17.9 25.2 14.3 29.5 17.2 15.2 19.6 27.6 6.1 26.8 23.2 24.5 25.9 14.8 3.1 16.8 24.6 23.9 27.2 77.0 14.0 33.0 27.3 18.1 41.8 20.2 17.4 25.6 12.7 13.6 14.1 12.8 71.9 21.8 35.5 16.1 18.6 14.6 22.9 52.2 12.9 21.4 10.9 18.3 27.7 22.4 6.4 17.7 8.3 26.0 52.1 14.1 16.8 30.4 17.3 17.0 7.8 8.2 28.3 8.8 29.2 19.7 15.0 29.0 25.5 0.0 4.6 0.6 6.2 4.9 5.4 4.7 3.3 5.8 5.2 1.9 3.0 5.5 0.8 2.8 2.4 6.5 3.2 2.7 17.0 12.0 12.2 16.1 13.3 5.4 10.3 4.2 10.6 1.7 9.2 12.7 20.5 3.2 8.2 5.5 5.2 0.0 5.4 0.0 8.0 2.5 7.5 7.6 4.3 17.2 3.1 14.7 20.9 23.8 10.7 7.5 7.9 9.7 167.4 9.1 18.6 12.4 8.5 12.8 5.4 5.3 20.2 22.8 9.7 11.3 14.0 191.2 21.4 65.7 22.0 11.8 7.8 9.7 0.0 16.7 0.0 180.4 14.3 8.9 0.0 6.5 11.6 8.1 12.3 4.5 16.3 3.1 6.0 9.8 6.7 4.9 6.9 25.4 0.7 2.2 6.6 8.7 10.4 16.1 24.2 13.0 0.0 15.2 6.6 27.1 11.8 4.4 UCHL5 "CGI-70, INO80R, UCH37" ENSG00000116750 "Ubiquitin C-terminal hydrolase L5" Q9Y5K5 1 193012250-193060080 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005908, HPA006069" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 18000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA005908: AB_1858585, HPA006069: " "unprognostic (3.66e-2)" "unprognostic (3.84e-3)" "unprognostic (5.17e-2)" "unprognostic (5.98e-2)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (7.41e-2)" "unprognostic (1.96e-2)" "unprognostic (1.04e-3)" "unprognostic (3.44e-3)" "unprognostic (6.92e-2)" "unprognostic (6.41e-3)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (4.33e-2)" 19.9 19.0 11.0 22.5 12.1 24.6 22.7 20.3 15.8 13.6 5.5 23.3 24.7 14.8 17.5 32.2 11.3 15.5 30.5 13.3 12.3 27.2 37.9 15.9 29.1 11.8 11.5 16.4 33.1 20.3 9.7 23.1 12.8 21.4 24.0 37.7 26.0 16.0 39.7 21.3 24.2 18.1 12.9 18.0 17.8 13.4 10.7 24.8 19.2 36.8 32.6 19.1 14.3 14.1 136.6 74.0 61.7 65.5 37.1 37.8 76.4 80.1 40.4 74.8 65.8 71.4 94.9 104.7 72.5 44.4 43.2 85.5 84.1 99.5 100.9 110.0 61.9 126.0 97.5 97.3 57.6 198.5 67.8 33.9 44.5 106.1 91.2 33.6 76.4 100.3 285.1 86.2 67.3 105.9 146.2 70.1 57.7 89.1 46.9 84.5 68.3 216.4 70.8 81.0 61.2 76.7 72.7 97.3 110.4 64.9 82.2 95.8 49.9 71.9 21.4 70.0 125.0 62.8 105.2 117.5 40.2 119.5 123.6 60.9 31.7 41.6 53.3 40.1 59.5 43.8 48.0 51.2 39.0 37.4 51.0 57.1 19.5 75.2 45.0 41.3 51.3 44.8 11.0 12.1 20.3 15.8 13.3 12.3 11.8 11.5 12.8 12.9 10.7 14.1 33.9 9.6 30.2 12.7 28.6 24.3 13.5 27.9 18.8 20.6 19.4 16.6 79.5 21.5 28.5 27.6 43.8 35.8 45.7 18.9 45.0 26.3 2.8 13.0 15.4 21.4 10.8 39.7 35.4 28.3 34.5 22.8 20.9 16.0 56.3 21.4 17.9 24.6 28.0 25.2 33.2 20.2 16.2 18.8 20.7 3.8 14.9 25.0 17.8 19.7 23.4 27.4 75.2 18.1 29.6 25.3 10.6 17.3 58.5 21.8 30.2 39.9 21.1 43.5 19.7 19.6 34.9 22.1 16.8 32.7 30.0 25.2 34.5 31.9 23.2 12.4 UCP3 SLC25A9 ENSG00000175564 "Uncoupling protein 3" P55916 11 74000277-74009085 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 80 "skeletal muscle: 393.2;tongue: 263.1" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Late spermatids: 14.0;NK-cells: 6.2;Skeletal myocytes: 6.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "HDLM-2: 15.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB010771, HPA072225" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB010771: AB_261839, HPA072225: AB_2686498" "unprognostic (3.76e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-1)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-2)" "unprognostic (3.95e-3)" "unprognostic (6.61e-2)" "unprognostic (1.25e-1)" "unprognostic (8.58e-2)" "unprognostic (2.13e-4)" "unprognostic (1.61e-2)" "unprognostic (3.25e-6)" "unprognostic (2.68e-1)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.50e-4)" 1.2 1.7 2.5 1.3 2.6 2.2 1.3 3.9 3.0 1.4 2.3 1.7 0.7 1.4 2.0 2.9 1.5 0.8 2.4 2.7 2.1 1.7 1.3 1.4 1.3 2.4 2.1 1.1 1.1 0.9 2.7 0.5 2.3 1.8 0.7 4.0 3.7 0.7 393.2 1.4 1.7 0.8 1.8 3.1 1.2 3.9 2.4 1.6 2.6 263.1 0.7 1.4 0.9 2.8 0.2 1.8 1.7 1.5 0.7 0.3 0.3 0.5 0.4 0.4 0.2 0.4 0.4 0.9 0.2 0.3 0.2 1.9 0.7 0.3 0.7 15.8 0.5 0.3 2.4 0.2 0.5 1.1 1.4 0.4 1.1 1.1 0.1 0.3 0.5 0.9 0.4 1.2 0.6 1.0 0.7 1.4 0.9 1.4 1.1 1.4 3.6 0.5 0.9 0.5 0.9 1.0 0.4 0.7 0.6 0.3 0.2 1.0 0.3 0.2 1.1 0.6 1.1 1.4 1.5 0.7 0.2 1.0 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.5 2.6 3.9 3.0 2.7 2.1 2.4 2.1 2.3 1.8 2.4 2.8 0.8 0.0 0.0 1.6 0.8 0.1 0.1 0.5 0.6 2.3 1.0 1.1 0.7 0.0 1.1 0.0 0.0 0.3 2.0 0.3 0.0 0.3 15.4 1.2 1.1 0.6 0.0 0.4 1.6 0.5 0.2 0.4 0.0 0.8 0.0 0.7 1.1 0.3 0.7 0.0 1.6 0.5 2.0 0.8 0.0 14.0 0.0 0.6 0.0 1.0 0.7 0.8 6.2 0.5 0.6 0.4 0.1 0.7 0.5 0.2 0.3 0.1 3.0 2.1 0.0 6.5 0.5 1.5 0.8 0.4 0.3 0.3 1.5 0.3 0.6 0.1 UFD1 UFD1L ENSG00000070010 "Ubiquitin recognition factor in ER associated degradation 1" Q92890 22 19449911-19479202 "Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 121.1;Ductal cells: 115.7;Exocrine glandular cells: 142.2;Extravillous trophoblasts: 107.3;Pancreatic endocrine cells: 149.9;Syncytiotrophoblasts: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 782.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030286, HPA030287" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" Nucleoli "HPA030286: , HPA030287: AB_10601830" "unprognostic (2.52e-1)" "unprognostic (5.41e-2)" "unprognostic (1.95e-3)" "unprognostic (7.61e-2)" "unprognostic (3.50e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-3)" "unprognostic (8.82e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (4.50e-8)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" 43.8 39.8 23.6 36.8 26.3 64.8 37.8 27.6 29.8 33.9 25.7 42.5 32.1 46.8 54.4 48.4 31.4 29.3 44.8 24.6 28.6 36.7 51.9 37.2 43.4 28.9 26.7 31.8 39.3 44.7 31.7 35.3 29.5 32.1 38.4 21.7 38.1 30.1 98.3 42.5 35.7 39.5 27.2 38.6 40.8 53.3 27.1 61.6 34.9 42.5 47.5 40.2 37.0 29.7 187.5 132.4 110.6 168.5 89.0 62.0 86.0 150.2 148.8 202.9 187.1 147.8 78.8 129.2 114.1 126.7 93.3 157.5 131.5 132.1 175.1 239.8 138.0 136.5 88.3 119.4 84.4 218.6 177.7 57.4 133.0 173.2 84.4 59.1 164.7 67.9 782.0 240.5 125.1 268.5 142.0 133.4 79.8 232.2 111.9 170.1 262.0 50.1 126.6 172.5 90.5 102.2 118.2 126.0 123.3 114.2 75.9 103.5 180.9 169.6 230.8 143.2 164.1 102.9 221.7 168.8 142.5 110.3 158.6 150.9 90.6 158.1 107.0 140.3 103.7 87.7 122.5 112.4 81.0 82.6 104.6 102.9 167.1 105.7 140.7 113.1 224.5 129.5 23.6 26.3 27.6 29.8 24.6 28.6 28.9 26.7 29.5 27.2 27.1 29.7 68.3 25.6 34.5 0.0 16.4 0.0 0.0 0.0 0.0 0.0 39.7 55.2 0.0 0.0 16.7 27.6 0.0 121.1 44.9 0.0 84.1 115.7 0.0 43.1 36.9 32.6 0.0 0.0 0.0 142.2 107.3 25.4 0.0 44.9 27.8 36.0 0.0 0.0 88.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 149.9 0.0 0.0 7.5 0.0 0.0 81.0 27.7 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.0 170.3 26.3 61.5 0.0 0.0 UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 858.6;tongue: 756.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 849.9;Hepatocytes: 559.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 417.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 13000000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 267.3 72.0 79.8 65.8 89.3 40.1 119.7 72.7 109.8 65.9 78.8 177.9 66.0 75.2 50.6 97.5 68.9 60.7 232.5 87.9 81.4 105.4 858.6 65.4 65.7 77.7 77.0 47.0 74.4 113.3 49.8 137.8 77.6 57.4 159.3 36.8 92.9 66.2 498.0 59.1 67.6 78.5 73.2 50.8 69.5 38.3 83.3 106.2 64.5 756.1 73.7 88.4 63.7 91.8 122.3 77.6 63.1 42.0 176.1 222.4 220.6 129.1 116.1 82.7 89.4 170.0 104.5 149.5 48.3 165.6 79.9 57.4 73.4 102.6 137.0 99.2 35.7 86.5 50.4 117.9 87.0 79.1 73.9 148.1 175.8 76.1 80.3 108.4 119.4 38.9 48.2 58.1 327.8 56.7 104.6 75.2 122.9 207.7 50.1 80.4 117.9 84.5 147.4 77.7 36.5 29.6 103.3 149.8 64.3 162.6 51.7 59.2 144.3 84.4 125.9 113.8 90.5 101.3 51.4 174.9 99.2 122.7 225.7 417.1 33.0 53.1 48.0 40.7 51.8 33.0 53.6 50.1 27.9 31.8 57.6 53.6 45.4 70.0 39.5 29.7 127.2 62.0 79.8 89.3 72.7 109.8 87.9 81.4 77.7 77.0 77.6 73.2 83.3 91.8 73.4 28.9 54.0 107.4 65.3 75.8 87.8 245.9 34.7 49.6 360.6 87.1 264.3 104.4 171.6 47.8 64.6 414.3 81.1 849.9 242.6 140.6 91.5 53.0 106.3 69.8 44.5 56.0 86.1 103.6 445.5 159.3 79.0 49.5 67.8 42.4 63.5 559.4 120.9 87.5 78.4 179.8 144.5 102.4 90.2 86.1 79.2 89.1 96.0 62.8 139.7 58.8 154.5 37.2 79.3 91.6 313.9 77.5 60.7 81.2 176.2 284.4 139.3 57.3 72.3 50.5 129.2 84.9 54.9 50.9 57.8 472.8 143.1 90.6 189.5 109.1 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 14.7;skin 1: 10.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 3.7;Early spermatids: 4.4;Late spermatids: 8.2;Proximal tubular cells: 3.8" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.8;JURKAT: 6.3;MOLT-4: 12.4;REH: 29.9;SuSa: 11.8;T-47d: 7.2;THP-1: 18.0" "Low region specificity" "Detected in many" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.0 0.8 0.0 0.0 0.0 6.5 1.1 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 2.6 0.6 0.0 0.0 1.0 1.1 0.0 0.0 0.1 0.9 0.2 1.2 0.4 0.0 0.1 0.1 0.0 0.1 10.3 0.0 0.0 0.1 1.2 0.1 2.9 0.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.3 0.4 0.0 1.3 0.0 0.5 6.8 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.4 0.0 5.3 0.0 0.0 29.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.2 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.0 1.1 1.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.7 0.0 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 1.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529631 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077624 Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA No "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA077624: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 26.8 23.3 21.2 23.3 24.6 40.3 19.3 18.1 21.2 15.1 16.6 19.2 19.1 11.7 14.1 13.3 14.4 13.7 11.6 26.0 28.3 31.2 38.1 17.5 30.8 24.9 28.5 11.9 11.0 27.8 7.8 17.1 28.3 16.2 19.6 10.5 13.5 18.5 25.8 11.9 23.4 10.8 19.8 25.4 20.0 12.2 26.1 24.6 19.4 25.9 28.9 18.1 10.5 19.4 61.9 28.4 14.6 35.8 40.7 31.9 32.7 79.7 43.2 63.9 45.7 18.6 37.8 50.2 67.8 60.0 31.2 34.9 28.2 44.1 102.4 69.1 20.4 49.8 34.3 16.9 31.3 73.4 55.5 33.0 45.8 63.2 59.9 44.6 37.4 34.2 44.1 67.7 111.4 26.0 39.3 19.4 19.4 46.1 37.8 24.9 64.9 41.9 42.6 62.8 26.4 24.3 70.5 64.6 52.2 19.9 56.0 81.0 58.5 72.7 41.0 50.8 112.6 69.2 103.5 58.0 60.5 35.3 67.3 3.6 2.0 2.4 4.8 5.3 4.9 3.2 3.5 4.0 2.3 3.6 3.5 4.0 1.3 3.7 6.1 2.6 3.1 2.6 21.2 24.6 18.1 21.2 26.0 28.3 24.9 28.5 28.3 19.8 26.1 19.4 37.6 19.2 41.2 20.9 75.6 29.4 33.7 38.5 34.7 24.4 39.4 20.2 35.1 40.0 53.8 53.3 12.5 26.2 81.0 53.9 56.7 27.6 55.6 35.1 35.7 33.4 33.5 51.6 37.0 23.2 38.1 25.5 43.3 44.4 45.7 23.3 31.1 85.1 30.0 23.5 27.4 34.1 48.8 73.5 47.5 58.4 21.5 60.0 28.4 33.7 58.0 14.6 74.2 20.6 29.5 40.4 33.0 19.5 47.2 59.9 60.8 62.2 50.9 23.0 0.0 29.2 27.8 25.1 29.6 45.2 24.6 22.4 69.4 31.4 39.3 58.3 UHRF1BP1 "C6orf107, dJ349A12.1, FLJ20302, ICBP90" ENSG00000065060 "UHRF1 binding protein 1" Q6BDS2 6 34792015-34883138 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032099, HPA032100" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" Cytosol "HPA032099: AB_10696057, HPA032100: AB_10671087" "unprognostic (2.30e-2)" "unprognostic (9.52e-2)" "unprognostic (4.58e-3)" "unprognostic (1.28e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.58e-2)" "unprognostic (4.39e-3)" "unprognostic (9.82e-2)" "unprognostic (4.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-1)" "unprognostic (1.90e-1)" "unprognostic (4.24e-2)" 4.3 4.4 2.8 4.3 2.8 14.2 3.6 7.1 3.2 2.7 4.6 3.1 3.2 3.3 2.4 3.2 2.8 2.5 6.8 2.4 3.4 3.7 3.9 4.2 4.9 3.5 3.7 3.3 8.0 8.5 3.0 5.3 3.9 3.6 3.9 7.5 5.9 2.9 14.3 3.1 3.6 3.9 3.5 4.4 4.0 12.0 3.5 5.8 6.0 7.5 4.2 3.5 2.4 3.8 12.9 9.1 7.9 25.9 4.1 3.0 14.3 7.4 5.0 7.1 10.0 18.2 3.4 19.4 7.9 7.7 12.3 9.6 29.2 4.2 9.6 10.0 9.4 17.2 8.7 15.2 16.7 15.7 10.3 6.8 12.0 5.7 12.0 6.6 9.1 16.6 29.3 7.5 3.1 12.3 12.2 10.2 3.6 9.3 6.3 7.3 12.7 11.8 9.6 11.8 9.5 9.7 18.7 9.7 24.7 8.1 18.5 20.3 5.6 3.5 12.7 5.5 8.2 11.1 18.6 12.0 1.9 21.5 8.8 0.1 0.3 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.2 0.1 0.4 1.3 0.1 0.1 0.2 2.8 2.8 7.1 3.2 2.4 3.4 3.5 3.7 3.9 3.5 3.5 3.8 5.1 16.0 6.3 16.0 5.0 1.0 3.0 3.9 5.7 10.1 5.2 2.9 16.8 4.3 9.1 0.0 20.9 6.9 3.7 3.0 1.9 5.4 10.0 5.8 4.9 6.3 9.5 6.7 20.8 5.8 3.8 4.9 10.2 11.5 1.3 14.3 15.0 6.0 15.6 5.0 39.3 4.9 10.2 19.0 6.0 18.2 5.6 11.9 0.0 22.5 9.4 4.6 4.1 25.6 14.1 7.2 3.3 2.6 11.4 9.9 4.1 3.9 5.1 10.8 13.1 7.5 5.4 16.4 10.8 8.3 2.8 4.9 3.9 4.0 3.8 8.5 UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142874 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" 8.7 10.9 6.2 10.2 7.7 32.9 8.8 11.0 11.5 7.2 9.9 8.3 8.4 7.5 7.0 7.0 6.3 8.9 7.9 13.2 6.2 12.3 24.6 7.7 9.2 4.9 5.4 7.5 3.8 13.6 5.2 9.0 4.8 9.0 7.9 14.6 6.4 8.0 19.8 5.9 7.1 8.8 4.6 9.2 6.0 14.0 3.7 8.4 10.9 14.6 7.0 10.1 5.2 9.2 18.6 19.7 10.8 11.2 16.4 23.1 21.6 28.3 28.4 22.4 16.3 14.8 6.2 16.0 7.2 29.1 13.1 6.9 20.4 9.7 21.5 42.7 10.0 10.7 14.1 17.3 15.1 20.4 16.8 13.1 8.0 27.0 18.6 20.7 16.0 11.0 8.6 16.2 22.1 10.3 13.1 17.5 18.7 6.3 17.7 14.7 19.2 15.7 11.4 32.2 18.3 11.4 21.4 24.5 8.5 9.2 21.9 23.0 12.7 24.6 13.2 21.5 20.1 19.1 35.2 22.3 12.4 15.1 15.2 21.6 11.4 7.8 3.6 12.3 5.3 5.5 4.0 4.1 12.8 4.5 3.4 4.2 33.9 5.9 10.9 7.6 5.2 5.4 6.2 7.7 11.0 11.5 13.2 6.2 4.9 5.4 4.8 4.6 3.7 9.2 10.6 28.9 8.7 27.1 18.2 12.7 17.2 5.0 19.9 11.9 9.3 7.5 15.7 1.5 12.6 9.2 4.2 4.7 15.0 10.9 5.9 6.0 35.1 15.7 23.7 8.6 5.4 9.4 75.2 5.9 8.9 24.7 7.7 9.9 24.1 6.3 5.3 18.5 11.2 15.2 54.2 2.1 4.1 23.3 21.4 5.3 7.2 29.5 10.6 45.0 25.7 8.3 8.2 37.2 29.5 5.9 7.4 7.9 12.5 18.5 8.9 14.9 21.8 12.0 0.0 23.3 15.1 24.1 19.1 14.9 11.6 10.9 15.7 8.3 5.7 11.9 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 352.3;Excitatory neurons: 108.6;Inhibitory neurons: 99.2;Late spermatids: 405.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 2.7 3.1 1.6 2.9 2.1 8.5 2.5 0.4 1.7 8.5 16.9 1.6 1.2 6.6 4.5 1.5 9.0 1.9 8.6 2.3 2.5 3.9 2.1 3.5 3.0 6.9 7.6 2.1 2.0 8.0 2.9 2.7 3.9 2.2 1.7 6.0 1.7 2.4 0.4 2.1 2.0 3.5 5.6 2.0 2.4 23.4 2.5 3.0 4.9 0.4 2.7 1.9 3.7 2.1 8.3 2.9 2.8 3.8 1.1 1.7 4.8 2.7 2.7 3.2 3.0 1.0 2.3 9.5 1.6 6.3 3.5 4.1 3.7 2.1 2.9 1.5 1.0 2.1 5.7 3.3 4.1 6.5 1.8 1.6 2.3 16.1 3.2 4.4 2.2 6.4 2.1 7.5 2.3 6.4 8.1 4.9 3.4 2.1 3.4 1.7 9.1 4.5 7.2 7.6 1.6 10.3 3.1 1.3 2.8 1.8 3.1 2.0 6.6 2.0 2.4 14.2 2.5 4.5 9.0 3.9 11.5 6.3 2.5 3.7 3.7 4.0 5.0 4.3 4.1 3.7 5.3 4.5 3.3 4.7 4.0 5.7 6.6 1.8 2.3 3.3 7.7 3.0 1.6 2.1 0.4 1.7 2.3 2.5 6.9 7.6 3.9 5.6 2.5 2.1 6.4 9.6 6.9 84.9 11.2 2.0 3.0 4.0 5.2 5.6 5.7 4.6 14.8 4.3 5.1 3.7 54.2 3.1 9.9 2.0 0.0 3.4 352.3 45.3 27.4 6.0 1.8 2.1 108.6 2.4 4.1 8.7 10.2 7.5 1.3 49.6 1.8 6.6 7.3 11.8 99.2 1.2 2.0 3.1 4.0 405.2 6.5 6.9 0.0 80.6 5.9 10.4 3.1 49.8 62.0 3.0 0.7 4.1 5.1 0.9 1.1 5.9 47.3 26.7 6.6 4.4 10.5 38.9 9.6 3.3 3.7 4.2 10.8 3.6 1.9 1.2 UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 80.7;Cone photoreceptor cells: 95.9;Excitatory neurons: 60.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: AB_1858618, HPA062300: AB_2684742" "unprognostic (9.73e-3)" "unprognostic (2.33e-1)" "prognostic favorable (4.96e-4)" "unprognostic (6.56e-2)" "unprognostic (9.93e-2)" "prognostic favorable (8.51e-5)" "unprognostic (7.64e-2)" "prognostic favorable (6.59e-5)" "unprognostic (3.80e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.71e-4)" "unprognostic (1.74e-1)" "prognostic favorable (4.34e-11)" "unprognostic (2.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" 12.6 12.8 10.5 5.6 13.3 1.0 10.3 6.6 14.5 12.5 15.7 22.2 11.6 10.1 7.7 17.5 10.4 11.5 13.6 11.4 7.2 21.8 12.8 38.9 1.8 8.3 9.5 7.3 21.3 15.0 11.5 6.0 7.8 22.6 25.0 41.2 17.8 23.3 24.2 12.3 13.4 11.9 7.3 4.7 17.9 15.6 10.6 3.0 12.2 10.4 5.0 10.2 12.7 9.0 9.8 12.8 13.9 22.6 26.3 14.6 11.8 15.7 7.1 11.4 15.3 10.7 4.5 0.0 7.0 20.6 20.1 4.7 35.4 18.2 14.5 0.0 11.3 5.9 36.6 13.9 12.7 2.2 6.4 11.6 14.0 18.0 18.5 18.2 37.3 15.8 13.5 8.1 13.5 7.5 2.1 0.2 12.6 30.2 13.3 0.1 8.6 3.4 15.5 12.6 14.9 15.7 11.0 6.8 11.4 23.0 11.6 7.5 34.5 7.8 7.2 12.3 12.2 12.7 16.2 0.0 8.5 18.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 13.3 6.6 14.5 11.4 7.2 8.3 9.5 7.8 7.3 10.6 9.0 6.7 57.7 80.7 28.7 0.8 3.1 1.1 2.1 3.4 42.3 7.3 4.4 11.4 18.6 16.7 9.2 95.9 3.7 0.1 24.4 3.9 6.0 6.9 8.2 5.1 8.5 24.6 1.7 60.4 12.2 2.1 4.8 16.3 13.9 2.5 8.7 5.7 12.5 4.9 6.7 17.7 31.9 0.0 2.4 3.0 12.3 2.1 3.7 7.2 73.1 0.1 5.7 0.0 42.3 36.7 7.8 11.9 3.0 4.2 11.7 10.5 7.8 10.0 40.8 6.6 8.4 6.5 8.7 7.5 14.3 7.4 2.9 1.0 5.7 19.5 5.7 UPF3A "HUPF3A, RENT3A, UPF3" ENSG00000169062 "UPF3A regulator of nonsense mediated mRNA decay" Q9H1J1 13 114281601-114305817 "Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 480.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018325, HPA061316" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA018325: AB_1858638, HPA061316: AB_2684477" "unprognostic (9.08e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-1)" "unprognostic (3.43e-2)" "unprognostic (2.51e-2)" "unprognostic (1.16e-2)" "unprognostic (6.48e-2)" "unprognostic (1.98e-1)" "unprognostic (9.80e-3)" "unprognostic (1.44e-1)" "prognostic favorable (7.09e-5)" "unprognostic (1.39e-3)" "unprognostic (1.52e-2)" "unprognostic (2.34e-2)" "unprognostic (9.21e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.71e-4)" 17.5 20.0 13.7 15.1 14.6 18.0 16.4 19.6 19.7 17.6 10.2 17.4 18.1 18.7 8.3 13.3 18.4 11.7 12.9 12.9 16.9 14.5 10.3 12.1 17.0 16.4 14.6 15.5 19.7 13.7 17.1 11.2 17.3 16.4 11.1 11.6 16.5 14.5 23.8 15.6 15.9 11.3 13.2 16.3 16.7 46.3 14.3 17.9 30.2 7.5 10.8 15.4 14.3 17.5 55.9 15.9 35.3 31.7 16.4 28.1 22.3 42.0 30.0 26.4 29.1 24.4 19.4 54.0 11.9 19.6 17.8 29.3 17.2 14.1 32.6 39.8 33.7 47.0 50.9 27.1 28.3 81.7 20.3 19.1 28.1 17.8 20.5 27.7 21.2 14.0 29.0 24.7 26.6 16.7 33.8 22.1 46.7 36.8 15.9 43.2 19.8 31.7 23.4 17.5 39.1 43.3 33.6 51.3 31.3 23.6 37.6 72.7 27.5 27.8 46.0 15.5 26.6 53.4 39.3 74.5 51.7 46.7 23.3 3.0 5.6 4.8 6.8 4.7 5.2 13.2 7.0 7.2 6.5 9.7 7.1 6.7 0.9 11.9 6.1 16.9 10.8 4.3 13.7 14.6 19.6 19.7 12.9 16.9 16.4 14.6 17.3 13.2 14.3 17.5 104.8 67.3 61.5 88.5 64.2 68.7 57.8 57.2 76.8 85.3 80.6 84.3 22.8 52.9 60.8 58.8 83.4 65.0 75.3 32.1 103.7 54.3 205.8 148.7 101.2 78.1 57.5 51.9 84.7 71.2 45.2 69.7 42.8 65.4 55.6 57.7 63.9 72.6 45.7 79.1 114.7 50.5 79.3 44.9 46.1 96.8 100.6 53.8 55.2 59.0 51.1 74.2 83.4 188.5 130.9 52.6 34.0 87.6 81.1 59.1 36.0 69.8 96.0 72.3 85.5 77.5 56.4 480.3 172.4 82.4 71.9 40.5 64.3 111.8 62.2 46.7 UPF3B "HUPF3B, MRX62, MRX82, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X" ENSG00000125351 "UPF3B regulator of nonsense mediated mRNA decay" Q9BZI7 X 119805311-119852998 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 157.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001592, HPA001800, HPA001882" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 6: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "Nucleoplasm, Nucleoli" "HPA001592: AB_2666373, HPA001800: AB_1080476, HPA001882: AB_1080474" "unprognostic (1.79e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" "unprognostic (3.64e-3)" "unprognostic (8.58e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (6.61e-2)" "prognostic unfavorable (5.39e-4)" "unprognostic (5.74e-2)" "unprognostic (4.51e-2)" "unprognostic (8.63e-3)" "prognostic unfavorable (1.44e-7)" "unprognostic (8.67e-2)" "unprognostic (1.04e-1)" "unprognostic (2.34e-1)" "unprognostic (8.95e-2)" 9.9 8.1 17.0 10.2 17.2 13.6 9.5 21.1 30.0 11.9 16.3 11.8 11.8 11.7 10.5 12.7 9.9 6.9 7.5 16.5 20.0 11.4 12.4 9.0 15.4 17.5 17.3 13.3 8.1 11.3 12.9 8.8 17.4 10.8 10.5 22.0 8.8 9.0 12.9 15.5 10.0 9.3 16.0 11.3 8.6 15.7 17.8 14.7 11.5 10.9 15.6 10.5 11.7 18.6 29.2 17.3 35.1 28.8 15.7 10.3 22.5 27.4 15.3 20.9 18.3 32.7 20.4 51.9 22.6 11.5 29.9 27.1 45.9 16.6 26.5 29.9 33.9 48.3 57.9 17.2 17.9 52.7 23.0 8.7 12.4 35.8 43.3 19.0 19.7 30.5 47.4 41.8 17.6 35.9 36.8 65.6 67.7 37.1 46.8 35.9 40.2 38.2 17.3 14.5 46.7 32.1 55.6 22.4 42.4 36.2 11.9 30.4 17.3 21.6 16.6 34.9 58.6 23.1 27.5 69.5 17.5 76.1 25.7 8.1 4.4 6.5 5.9 4.8 4.8 12.5 5.6 4.8 3.3 13.7 6.3 6.4 4.9 7.7 5.6 8.7 7.4 2.2 17.0 17.2 21.1 30.0 16.5 20.0 17.5 17.3 17.4 16.0 17.8 18.6 26.3 32.1 25.7 31.6 47.4 37.7 31.1 31.6 47.8 50.7 26.4 28.2 19.0 17.2 38.7 25.8 56.3 39.0 46.1 33.5 5.9 31.6 157.3 26.1 23.5 31.1 27.6 52.2 30.6 26.4 48.2 25.5 23.0 33.8 58.9 32.8 23.2 22.9 28.5 28.6 39.5 35.5 26.4 19.1 43.3 31.7 30.4 28.2 24.9 27.2 44.9 32.6 56.7 33.7 45.4 21.5 33.6 32.7 32.5 33.8 30.4 16.5 35.2 99.0 13.1 34.4 42.0 65.8 41.4 38.8 38.1 64.3 39.9 28.1 37.6 25.0 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 45.8;liver: 23.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Distal tubular cells: 13.7;Excitatory neurons: 32.5;Inhibitory neurons: 20.8;Oligodendrocyte precursor cells: 27.6;Proximal tubular cells: 82.1" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 0.0 0.1 3.3 0.0 2.9 0.0 0.0 1.8 3.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 3.7 1.9 45.8 23.9 0.0 0.1 1.3 1.3 0.3 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.9 1.8 3.0 3.7 1.9 1.3 1.3 1.1 1.4 1.6 2.4 0.0 0.0 0.0 24.2 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 0.0 20.8 0.0 0.0 0.9 0.0 0.1 0.3 0.5 0.0 2.8 0.0 0.1 0.0 27.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 82.1 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.6;Inhibitory neurons: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" 19.4 30.0 22.0 13.8 24.3 4.6 16.5 21.9 27.7 20.1 20.9 26.0 18.9 18.6 22.9 18.8 20.6 12.6 55.3 22.4 23.0 28.6 27.1 15.8 17.9 24.1 23.5 19.8 15.9 37.2 23.9 14.9 26.6 19.7 25.8 29.5 18.7 18.4 106.8 16.3 19.3 18.5 19.9 19.7 23.0 17.6 22.9 21.2 22.3 105.7 21.9 20.1 18.0 22.8 20.2 28.6 33.5 32.2 34.1 38.4 4.8 38.5 43.3 70.7 48.1 97.7 39.4 66.6 68.5 26.1 60.7 53.5 60.0 70.0 52.6 19.0 24.2 89.2 41.3 80.3 22.7 54.2 25.6 37.6 72.3 37.9 48.8 51.2 24.6 53.5 39.9 23.9 50.0 26.8 58.6 29.2 25.4 42.0 61.5 31.4 50.0 37.9 67.6 26.2 46.4 28.7 32.9 148.9 34.0 28.1 23.9 34.6 23.5 46.2 28.8 25.9 34.6 30.1 37.2 26.5 79.7 31.1 36.8 28.6 10.2 14.2 14.8 14.3 18.3 12.3 13.7 14.7 16.0 15.7 16.7 14.7 0.3 22.3 10.2 14.4 14.2 12.6 22.0 24.3 21.9 27.7 22.4 23.0 24.1 23.5 26.6 19.9 22.9 22.8 7.0 0.0 7.8 51.6 7.0 6.4 9.3 18.1 6.8 20.7 7.8 5.8 44.0 10.0 11.8 16.5 8.4 22.9 5.3 13.9 60.7 18.2 15.1 10.5 8.5 10.5 12.0 5.2 64.6 13.1 15.7 9.2 7.7 6.9 8.2 17.5 6.1 14.2 11.6 18.5 68.9 9.1 18.3 6.6 3.9 8.6 10.5 5.8 14.2 33.7 13.2 16.7 10.3 44.2 50.3 19.1 6.6 12.0 5.0 8.4 10.9 19.4 14.8 22.8 6.6 9.6 11.9 24.6 18.2 6.2 5.3 17.4 6.2 19.7 13.2 9.6 UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 209.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Mitochondria" Cytosol "HPA046851: AB_2679839" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (3.42e-2)" "unprognostic (3.91e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (2.18e-1)" "unprognostic (1.67e-1)" "unprognostic (8.70e-3)" "unprognostic (7.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.07e-2)" "unprognostic (7.21e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" 7.5 12.2 7.4 3.7 7.5 5.7 7.5 8.2 9.7 7.6 9.3 9.9 8.1 6.5 1.7 12.3 6.1 1.2 10.2 7.1 7.1 10.7 11.9 4.7 4.2 7.6 7.3 6.5 9.0 3.5 6.7 2.2 7.7 9.4 1.9 3.9 11.5 3.3 15.7 9.0 8.3 1.5 7.0 7.4 9.6 3.4 7.4 2.4 6.3 5.0 1.6 6.3 8.1 8.1 26.9 52.9 7.7 12.0 4.7 4.6 6.5 10.4 3.5 7.7 7.6 31.4 22.8 17.4 21.1 3.6 10.4 26.1 7.4 12.3 2.4 8.8 27.4 9.8 28.7 20.3 6.3 16.0 7.6 4.4 10.3 6.8 7.6 4.8 6.0 8.1 21.3 12.2 4.3 82.4 15.7 39.2 8.6 10.6 29.8 17.9 11.7 31.1 6.1 13.2 15.5 15.7 11.5 41.7 16.2 2.4 39.7 14.9 7.9 16.8 19.7 17.6 23.6 18.7 11.0 18.3 13.8 13.7 12.3 14.6 25.0 20.1 21.3 19.1 20.4 30.8 21.1 19.0 20.0 29.9 19.2 15.3 11.0 19.6 17.2 26.7 25.8 20.0 7.4 7.5 8.2 9.7 7.1 7.1 7.6 7.3 7.7 7.0 7.4 8.1 49.0 44.8 25.0 3.6 32.3 0.0 42.2 0.0 47.3 21.8 77.5 86.4 35.8 70.1 16.1 64.4 16.7 53.1 22.9 65.2 140.8 56.6 1.7 50.3 40.6 32.9 35.2 32.2 2.4 78.4 53.1 32.4 54.6 41.1 5.1 28.0 44.6 125.4 54.8 18.5 4.2 75.2 0.0 39.7 0.0 3.7 48.4 29.2 0.0 7.5 47.2 59.7 66.9 5.0 5.2 67.4 66.9 36.1 38.4 85.1 209.3 170.6 12.4 37.0 39.5 28.3 31.8 4.2 32.0 91.0 0.0 29.0 25.3 35.1 79.0 57.0 USF3 KIAA2018 ENSG00000176542 "Upstream transcription factor family member 3" Q68DE3 3 113648385-113696646 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029243, HPA029245" Uncertain Uncertain Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli" Centrosome "HPA029243: AB_10611114, HPA029245: AB_10600443" "unprognostic (2.80e-2)" "unprognostic (2.80e-1)" "unprognostic (4.21e-2)" "unprognostic (7.80e-2)" "unprognostic (2.25e-2)" "unprognostic (1.96e-2)" "unprognostic (3.53e-1)" "unprognostic (2.62e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (8.74e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (3.28e-1)" "unprognostic (5.55e-2)" 7.1 4.9 5.6 3.0 5.9 10.2 6.7 8.8 8.0 5.5 7.5 7.5 2.8 5.3 7.8 6.8 6.2 2.4 7.0 6.2 5.3 8.2 16.4 5.9 5.3 5.4 5.4 5.8 8.5 6.0 6.7 2.8 5.6 5.9 3.9 5.6 6.4 2.7 18.7 7.4 8.3 2.4 5.2 8.7 7.5 4.8 5.3 6.7 6.2 8.5 4.6 6.0 6.1 6.8 4.6 3.4 4.1 3.9 9.8 3.7 2.8 1.8 2.9 1.7 1.6 3.2 1.9 8.0 3.2 4.6 2.8 2.8 4.5 3.6 3.3 2.7 1.9 5.7 2.2 5.3 2.9 10.5 6.2 5.5 6.4 3.2 3.6 2.6 4.2 5.9 2.7 4.1 3.7 6.4 5.9 5.8 3.0 6.1 3.4 2.5 3.2 3.2 6.3 6.3 1.9 3.0 4.3 2.4 5.5 2.8 3.3 7.7 5.7 2.7 6.0 1.5 2.6 4.8 2.9 9.2 3.1 4.3 2.0 2.2 1.0 1.7 1.3 1.3 1.0 1.0 0.9 1.0 0.8 2.3 1.1 1.2 3.2 1.2 1.8 2.3 0.5 0.7 5.6 5.9 8.8 8.0 6.2 5.3 5.4 5.4 5.6 5.2 5.3 6.8 27.1 22.4 15.1 0.0 30.1 0.0 11.2 0.0 15.9 19.5 19.7 12.6 0.0 14.3 6.2 25.8 14.6 8.1 42.7 13.1 25.4 8.4 6.7 28.3 18.6 15.6 6.1 17.0 0.0 11.8 4.2 13.3 18.3 22.8 5.1 6.7 20.3 46.3 7.8 13.5 0.0 10.2 0.0 22.6 0.0 10.9 13.1 17.0 0.0 0.0 16.4 12.4 29.9 0.0 0.0 12.5 12.4 13.9 17.5 18.4 23.6 29.2 12.4 18.8 6.6 27.6 13.8 13.1 6.0 15.8 0.0 14.5 20.0 12.2 10.9 19.5 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 176.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 297.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Nucleoplasm, Nuclear bodies" "HPA006237: AB_1080502, HPA006428: AB_2667588, HPA071014: AB_2686333" "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 29.0 21.6 4.5 29.4 4.8 176.2 22.9 12.3 6.7 17.6 10.2 18.0 13.8 14.6 9.2 19.7 17.8 13.7 19.8 5.2 5.5 14.9 27.2 31.5 33.3 6.0 5.4 26.7 19.7 14.9 13.9 18.4 5.7 14.3 16.7 45.8 19.7 8.3 35.5 29.9 24.6 12.6 4.6 44.3 18.8 30.2 5.5 26.5 17.1 14.8 24.9 18.1 19.4 8.0 18.3 16.5 14.2 17.7 25.7 25.1 27.0 29.0 21.2 22.3 16.1 19.6 21.6 15.5 16.6 17.8 10.1 18.5 18.4 23.1 27.6 18.5 15.0 25.2 15.1 14.1 18.8 35.6 61.8 15.0 19.2 27.2 20.7 20.7 26.1 16.3 80.8 36.0 20.0 23.5 26.4 19.3 25.4 16.5 24.0 17.2 19.1 32.3 17.9 22.8 17.9 8.9 30.9 21.6 17.3 17.4 34.7 18.8 37.2 21.2 22.2 32.0 18.2 16.4 24.0 21.9 25.7 26.7 23.5 163.4 60.0 64.3 13.5 31.1 14.9 28.5 19.6 14.0 23.7 20.5 23.5 13.8 297.9 14.7 26.8 26.6 58.8 26.1 4.5 4.8 12.3 6.7 5.2 5.5 6.0 5.4 5.7 4.6 5.5 8.0 57.1 38.5 36.4 68.6 130.3 58.8 40.8 26.2 40.5 54.9 32.3 28.1 74.9 21.5 48.9 23.9 110.5 31.7 142.5 50.2 11.7 36.4 172.2 26.3 46.5 45.4 42.0 248.3 124.8 41.5 43.3 52.5 57.6 38.9 88.6 53.5 21.0 45.3 46.2 42.1 104.2 33.2 12.2 101.3 97.6 172.0 61.8 120.6 53.4 135.9 195.8 25.6 90.6 100.0 108.8 55.1 47.6 29.3 94.3 36.0 30.9 25.9 31.9 151.5 39.5 66.1 60.5 83.7 43.3 49.3 77.0 65.8 130.0 27.0 29.5 60.8 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881828 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 95.9;K-562: 60.2;MOLT-4: 56.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (2.48e-4)" "prognostic favorable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favorable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favorable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 8.1 12.0 8.7 13.5 8.0 22.6 8.3 4.8 8.7 12.5 2.5 13.6 8.2 12.5 4.2 7.9 12.1 7.7 7.5 7.8 10.6 7.6 7.4 8.4 18.3 10.2 9.1 13.5 10.9 8.4 18.4 6.7 10.0 14.8 4.9 6.7 11.4 13.2 10.9 12.1 12.5 8.2 5.4 13.9 9.9 10.0 8.9 32.3 18.7 7.5 11.8 14.9 10.1 6.5 6.0 5.8 10.0 13.4 12.8 10.8 14.1 9.5 7.9 7.1 4.9 4.7 6.5 8.1 8.0 9.3 8.0 14.7 6.0 6.7 2.9 43.4 7.9 14.9 17.0 3.3 8.8 14.2 10.6 9.6 9.8 9.3 7.0 12.4 7.7 95.9 60.2 9.9 4.4 15.9 56.4 33.6 7.9 12.7 13.6 9.4 11.2 14.0 5.5 6.5 2.2 11.0 11.0 13.9 9.1 5.9 14.4 19.9 11.5 7.8 3.5 10.5 6.3 9.7 15.3 5.7 15.5 18.6 7.4 1.0 1.9 5.4 8.6 1.5 9.1 3.7 8.7 8.3 2.6 3.4 9.8 8.9 2.8 10.0 1.5 2.1 11.5 6.3 8.7 8.0 4.8 8.7 7.8 10.6 10.2 9.1 10.0 5.4 8.9 6.5 3.0 9.6 6.9 16.3 9.2 2.8 2.2 2.5 4.0 7.8 6.4 8.0 7.7 4.3 3.0 1.8 4.2 5.9 9.4 6.2 3.9 2.4 2.1 4.1 6.3 4.3 8.4 12.8 17.0 4.0 2.5 4.6 8.2 5.7 1.3 6.8 6.4 6.1 3.3 10.1 21.1 4.6 4.1 1.6 3.8 3.3 6.2 6.0 3.6 11.2 3.1 5.3 11.3 9.5 14.3 2.7 5.0 4.9 6.7 3.0 4.1 2.9 5.0 6.3 0.0 4.3 5.7 12.1 6.0 4.8 2.0 6.2 19.3 2.9 5.2 1.6 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favorable (3.35e-5)" 12.2 15.3 19.6 11.9 20.7 15.0 14.3 18.5 22.8 19.4 18.3 17.6 13.6 18.2 12.0 16.4 28.0 12.0 13.0 19.4 18.4 14.5 10.8 13.1 16.1 19.2 19.7 23.2 16.4 17.1 15.7 13.2 18.7 17.7 11.0 12.9 16.5 20.3 20.9 20.8 15.9 12.6 17.3 17.8 16.4 14.2 20.1 18.4 18.5 17.7 14.0 17.6 16.8 22.1 12.5 20.6 26.9 26.2 21.1 17.5 16.5 9.1 14.6 24.2 18.9 19.4 23.3 16.0 14.6 11.2 15.1 20.7 17.6 17.5 13.2 30.8 30.0 19.3 34.1 15.3 15.2 17.4 13.4 14.8 23.0 16.6 23.9 27.1 17.3 35.0 28.4 21.6 15.6 22.6 30.7 26.9 25.2 24.3 26.1 28.8 9.0 26.5 14.4 14.9 24.2 31.5 17.2 17.2 13.9 20.1 37.3 27.5 10.1 16.9 14.8 11.9 15.3 42.9 36.5 23.9 15.3 14.7 15.5 15.2 10.0 17.1 12.6 6.4 14.6 11.0 11.5 13.2 10.8 11.3 13.1 12.3 8.4 13.3 7.6 10.8 12.3 11.0 19.6 20.7 18.5 22.8 19.4 18.4 19.2 19.7 18.7 17.3 20.1 22.1 4.5 0.0 3.7 5.2 6.5 1.5 1.8 2.4 16.5 5.0 4.9 4.1 3.9 8.6 2.9 1.8 6.2 4.9 3.6 3.6 1.9 2.0 1.0 6.3 5.7 4.4 5.4 10.7 2.4 2.3 2.3 5.1 9.2 3.7 2.5 4.5 5.3 2.1 2.2 0.0 2.7 4.0 4.1 4.8 0.8 1.0 5.0 2.1 1.8 1.9 1.2 3.3 5.2 2.0 4.6 2.0 2.4 4.1 7.8 2.7 3.5 2.5 9.5 5.2 6.6 2.0 5.2 5.3 3.2 10.7 1.4 3.1 5.6 3.1 4.1 1.5 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: AB_2681974" "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 43.9 37.9 20.0 21.5 21.9 46.6 32.9 29.3 23.9 32.6 27.5 31.2 13.4 26.8 22.9 25.0 34.2 18.7 30.2 21.4 20.6 34.4 30.3 36.1 20.6 22.6 21.3 67.4 44.5 18.1 50.3 26.0 21.5 36.2 15.8 26.3 24.9 13.1 30.3 40.4 26.6 16.3 19.4 30.7 31.2 22.2 21.2 15.1 31.6 11.7 20.5 29.3 29.8 30.1 42.7 50.3 14.6 26.9 30.5 33.7 27.8 34.1 34.5 32.1 21.5 49.2 21.0 54.0 16.9 30.6 34.8 30.6 34.5 25.4 57.0 13.0 52.1 49.4 81.0 51.9 31.3 54.7 26.0 29.5 41.0 45.8 101.6 24.7 28.3 24.1 40.0 55.3 26.8 32.6 50.1 55.1 22.6 31.6 39.9 38.1 31.8 36.3 20.2 44.1 42.8 25.8 24.5 112.5 63.7 31.3 29.2 34.4 24.3 75.2 35.3 44.3 61.1 40.7 17.4 66.1 29.6 41.9 24.0 10.1 3.0 2.4 5.5 4.2 6.5 5.1 5.2 4.8 1.8 4.7 5.7 5.6 4.3 4.5 2.7 9.7 3.8 1.9 20.0 21.9 29.3 23.9 21.4 20.6 22.6 21.3 21.5 19.4 21.2 30.1 27.4 12.8 37.4 23.5 55.9 51.7 28.4 8.2 40.9 33.2 18.1 16.9 14.1 18.6 18.8 14.7 33.3 8.3 66.3 14.4 5.9 10.2 20.7 22.3 24.0 28.4 18.5 14.7 19.0 9.6 11.3 26.6 25.0 42.7 20.3 12.8 12.1 16.5 43.3 26.9 22.5 18.6 10.2 24.5 72.8 8.5 11.8 49.4 30.2 10.3 14.9 13.2 16.5 13.6 19.8 13.2 8.4 12.4 57.1 32.4 7.3 5.0 11.1 32.1 6.6 22.1 23.1 18.4 16.5 24.4 43.3 12.9 73.6 13.1 18.6 22.2 USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223874 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 36.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 65.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA036990: AB_2675419, HPA047948: AB_2680220" "unprognostic (5.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.04e-3)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.49e-2)" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (8.03e-2)" "unprognostic (7.72e-3)" "prognostic favorable (1.20e-4)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" 6.5 4.4 2.5 6.2 4.3 21.6 4.6 4.3 2.9 6.2 4.3 8.0 7.9 5.5 2.3 7.0 4.3 5.2 6.8 2.2 2.4 7.0 13.2 6.3 6.4 5.9 3.8 3.7 8.2 7.7 3.3 8.1 4.9 5.5 5.7 4.5 5.8 5.6 36.6 5.9 7.2 5.7 4.9 7.4 6.3 6.8 3.2 9.3 7.4 21.3 5.8 6.8 3.9 6.8 8.5 7.9 6.6 11.3 8.4 8.2 5.1 13.0 12.5 11.8 10.1 23.1 11.7 10.5 9.2 11.5 7.8 6.5 15.9 13.5 10.2 26.0 10.5 9.7 8.5 4.7 11.3 19.4 9.4 10.2 11.1 12.0 9.5 8.3 12.2 11.9 21.5 31.5 7.9 13.3 25.6 3.7 6.1 17.7 15.3 16.7 10.2 10.1 7.2 9.2 13.8 12.3 10.5 17.3 10.9 4.9 10.8 7.6 14.6 10.8 9.1 9.6 14.1 35.7 65.3 18.6 10.9 14.4 9.3 13.4 4.5 9.7 5.7 4.6 7.0 4.6 4.9 4.9 6.6 4.5 4.8 4.2 4.3 10.1 4.9 2.7 7.9 4.3 2.5 4.3 4.3 2.9 2.2 2.4 5.9 3.8 4.9 4.9 3.2 6.8 21.5 22.4 19.8 13.7 19.5 53.5 21.0 6.2 25.6 7.4 20.8 13.7 18.4 10.0 12.2 0.0 12.5 12.8 22.2 35.5 1.9 8.3 36.4 20.7 26.1 15.3 30.6 31.5 19.6 7.7 7.1 13.4 26.0 52.1 3.8 9.9 17.9 38.4 10.6 8.4 15.9 20.2 4.1 17.0 16.6 20.3 6.8 21.9 12.4 9.4 10.1 15.1 12.3 18.6 22.8 10.2 13.4 9.4 38.6 16.8 17.0 18.5 10.9 8.9 13.1 15.0 14.1 11.3 4.7 31.5 59.1 26.7 23.2 11.0 17.6 45.4 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 25.8 47.5 18.7 26.6 24.5 43.5 26.4 31.0 26.4 26.9 21.6 24.4 21.7 25.3 20.4 23.0 22.3 18.9 21.6 19.3 20.4 18.2 23.8 23.1 35.1 20.1 20.4 31.1 24.6 25.2 26.9 27.3 21.7 23.5 26.0 57.0 31.2 18.6 23.1 29.5 28.7 22.9 18.5 36.0 32.5 20.6 20.8 26.9 28.6 19.5 34.5 23.1 24.6 36.0 43.9 20.5 47.0 34.0 40.1 49.0 46.4 54.0 36.5 35.3 46.6 19.1 43.2 49.1 35.6 48.8 27.5 39.2 59.0 43.4 53.6 48.3 42.1 104.3 75.7 34.5 35.5 53.0 53.7 39.8 36.6 36.1 39.7 48.1 106.1 36.2 83.8 133.2 44.0 21.9 44.2 68.5 29.7 44.5 36.8 61.3 47.2 57.3 40.7 36.2 57.1 35.6 50.4 45.7 122.7 62.3 23.4 63.0 76.1 37.7 30.9 46.7 31.8 105.6 81.7 48.1 36.3 64.5 56.6 82.1 19.5 35.0 12.2 9.4 13.9 28.6 17.8 17.9 21.1 29.8 20.5 13.1 16.8 12.2 10.9 15.3 21.4 12.6 18.7 24.5 31.0 26.4 19.3 20.4 20.1 20.4 21.7 18.5 20.8 36.0 37.9 54.5 42.1 32.0 55.4 22.2 25.1 30.3 33.0 86.5 22.2 24.5 65.3 21.5 24.4 20.2 62.6 61.4 48.3 17.8 25.4 28.5 71.4 33.3 48.5 32.5 21.7 88.1 66.4 20.0 56.3 42.0 33.1 41.4 49.9 200.4 27.5 22.1 29.2 50.5 74.2 31.3 32.6 22.6 28.1 47.7 34.8 34.4 58.7 52.5 55.9 30.7 36.0 54.3 112.3 23.8 16.4 51.6 150.1 20.7 24.1 20.2 27.3 69.2 32.9 51.7 39.8 52.7 47.4 35.1 25.7 32.6 41.8 54.8 31.6 21.6 UTP18 "CGI-48, WDR50" ENSG00000011260 "UTP18 small subunit processome component" Q9Y5J1 17 51260546-51297936 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.6;Late spermatids: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052378 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear membrane" "HPA052378: AB_2681805" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.62e-2)" "unprognostic (2.55e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.47e-2)" "unprognostic (8.37e-3)" "unprognostic (1.10e-2)" "unprognostic (8.82e-2)" "unprognostic (2.75e-2)" "unprognostic (3.11e-3)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-3)" "unprognostic (1.93e-2)" 17.9 20.1 12.6 24.9 13.7 40.0 25.8 19.1 15.7 18.8 14.2 17.5 17.8 15.7 15.8 21.0 17.5 12.8 10.2 13.2 13.8 21.8 22.3 17.3 33.1 13.0 12.3 23.8 21.3 23.3 20.4 26.3 13.6 16.2 18.7 17.5 17.4 14.2 24.4 32.3 16.5 12.9 13.0 24.5 18.1 58.7 13.2 27.7 24.4 16.2 34.4 24.8 18.0 15.6 90.5 87.7 54.6 50.3 35.1 52.2 142.2 48.9 40.2 83.5 79.7 55.4 49.3 113.5 67.8 36.6 89.0 48.1 89.7 52.0 123.3 74.8 117.0 119.4 52.6 97.3 48.0 127.9 56.4 33.9 39.5 71.1 57.0 42.1 50.7 55.6 98.7 50.6 63.5 56.1 115.6 86.9 78.5 127.5 91.8 103.2 124.2 89.4 61.3 59.1 60.7 76.9 56.7 66.6 114.7 67.4 82.3 64.4 44.7 85.3 71.8 71.1 102.9 97.4 192.5 131.5 53.0 87.6 62.4 19.0 48.2 27.9 40.2 46.9 49.9 54.1 50.7 49.2 55.9 52.4 53.6 51.1 8.2 40.0 49.0 35.0 56.8 56.2 12.6 13.7 19.1 15.7 13.2 13.8 13.0 12.3 13.6 13.0 13.2 15.6 20.6 16.0 23.4 11.8 37.4 60.2 62.9 40.6 33.0 15.6 19.6 17.9 4.4 20.0 25.2 14.7 14.6 66.7 27.4 11.4 39.2 38.4 190.6 26.3 27.3 25.1 16.1 20.8 18.5 46.9 71.2 24.5 14.3 24.1 31.7 19.6 8.9 17.1 62.8 10.1 18.0 20.7 34.6 37.7 26.1 182.0 26.8 33.3 23.2 15.0 42.2 21.3 25.7 17.6 24.6 34.2 16.3 22.2 24.2 50.2 13.8 37.5 38.8 11.8 13.1 24.8 35.7 140.2 104.5 27.7 52.7 79.6 30.4 30.8 25.3 48.1 UTY "KDM6AL, KDM6C" ENSG00000183878 "Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked" O14607 Y 13248379-13480673 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Excitatory neurons: 66.7;Inhibitory neurons: 65.2;Oligodendrocytes: 65.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 20.6;SK-MEL-30: 14.9;U-266/84: 16.4;U-698: 20.2" "Low region specificity" "Detected in all" "HPA000568, HPA001165" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Nucleoli rim" "HPA000568: AB_1858705, HPA001165: AB_1080541" "unprognostic (7.52e-2)" "unprognostic (6.60e-2)" "unprognostic (4.04e-6)" "unprognostic (6.47e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.41e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-2)" 3.6 3.5 0.9 2.4 1.5 6.8 3.5 2.0 2.2 0.0 1.6 2.9 2.5 0.0 9.4 4.1 0.0 3.5 2.9 0.9 1.2 3.1 4.1 4.2 2.1 2.1 1.1 0.0 3.4 2.9 4.0 3.4 2.1 8.1 6.2 4.5 4.3 6.2 5.7 5.1 6.3 0.0 1.3 3.4 2.9 3.8 1.4 0.0 3.8 5.2 6.0 3.6 0.0 3.2 0.0 2.5 0.0 0.0 0.0 0.0 8.7 4.5 7.7 5.0 7.5 0.0 0.0 12.4 0.0 5.1 0.0 0.0 0.0 0.0 6.9 6.9 0.0 20.6 0.0 0.0 6.4 0.0 0.0 7.8 7.8 0.0 0.0 0.0 0.0 4.2 0.0 0.0 5.5 0.0 7.1 0.1 0.0 0.0 0.0 0.0 3.1 5.6 5.4 8.3 4.9 0.0 0.0 0.0 14.9 8.5 0.0 4.4 5.9 8.7 0.0 0.0 3.1 13.5 16.4 20.2 0.8 0.0 0.0 1.8 1.7 3.8 2.6 1.9 3.7 2.9 2.6 2.1 1.8 3.2 3.6 2.7 3.9 5.8 2.2 2.9 3.2 1.1 0.9 1.5 2.0 2.2 0.9 1.2 2.1 1.1 2.1 1.3 1.4 3.2 0.0 16.0 25.3 58.4 35.4 11.3 18.4 8.2 44.3 35.2 0.0 0.0 6.1 5.7 10.7 18.4 64.6 10.0 8.0 3.0 0.0 4.8 0.4 0.0 0.0 9.0 1.8 19.6 66.7 0.0 3.7 9.3 37.8 0.0 16.4 0.0 12.5 2.1 3.0 37.0 65.2 3.3 2.0 14.2 14.5 2.0 10.8 12.7 8.8 54.4 18.1 12.8 25.7 57.8 65.8 1.5 2.2 11.7 23.2 14.0 2.9 2.6 10.7 37.4 0.0 4.7 5.0 4.0 6.8 33.2 15.3 13.3 25.1 0.0 2.9 21.3 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 443.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Cell line enhanced" "Detected in all" "HMC-1: 270.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" 54.5 24.6 9.3 75.2 8.3 94.0 42.5 9.2 12.6 37.7 11.0 88.9 61.9 89.1 6.0 37.5 54.4 27.0 36.4 8.1 9.4 39.1 27.3 58.2 48.7 13.0 10.9 22.5 20.6 10.7 17.1 31.5 13.8 43.8 20.4 1.9 30.7 39.1 12.5 32.8 63.6 36.5 11.7 107.0 70.5 14.7 15.0 24.9 27.6 8.5 32.0 71.6 39.0 12.0 68.9 66.3 20.6 35.6 10.2 17.4 50.5 70.2 52.8 47.4 40.9 30.1 142.0 31.2 55.7 56.4 31.3 60.6 6.2 69.5 15.9 87.0 14.8 183.7 32.3 55.4 56.6 68.1 270.1 26.8 38.2 44.5 28.5 38.3 71.1 25.8 112.1 67.5 29.4 53.7 30.3 58.7 36.0 65.1 44.5 21.6 12.6 12.2 40.9 216.2 23.0 16.3 83.6 41.7 48.2 13.0 45.7 115.2 107.0 74.7 74.4 24.7 112.4 32.8 43.3 54.7 52.4 82.3 92.3 13.3 8.5 52.7 4.1 13.9 2.8 3.4 3.3 3.9 5.5 3.3 2.1 2.5 34.5 4.0 22.7 2.1 2.6 5.8 9.3 8.3 9.2 12.6 8.1 9.4 13.0 10.9 13.8 11.7 15.0 12.0 80.9 16.0 19.5 2.9 99.4 98.3 95.6 48.8 37.0 6.9 53.5 57.0 19.0 48.6 41.5 33.1 27.1 67.1 85.9 202.3 17.6 138.6 3.2 33.9 30.5 77.0 114.7 20.0 2.6 98.2 443.6 26.7 81.6 58.1 83.1 17.4 48.5 15.8 160.1 6.7 3.4 159.3 44.7 132.5 232.0 3.8 26.1 192.9 49.8 10.3 162.9 13.2 185.3 2.0 2.3 212.5 245.5 49.2 38.2 73.4 134.6 20.4 18.6 14.7 131.5 46.5 89.4 18.9 15.5 38.7 77.7 140.9 95.7 21.0 129.5 144.8 VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 235.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 141.7;Proximal enterocytes: 88.7;Undifferentiated cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.5;monocytes: 6.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 55.5;HDLM-2: 80.0;U-937: 85.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 4.3" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: AB_628040, HPA047740: AB_2680142, HPA072102: " "unprognostic (1.11e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.59e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (6.72e-2)" "prognostic favorable (4.89e-6)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (3.82e-2)" 3.6 13.7 0.2 13.3 0.2 8.2 11.3 0.2 0.4 5.0 0.9 40.4 56.0 1.6 0.4 13.6 1.8 8.5 1.2 0.2 0.7 21.0 1.1 7.7 5.3 0.7 0.4 0.5 2.1 235.9 11.1 2.9 0.6 1.9 35.3 0.2 6.1 1.8 2.8 22.1 55.0 3.8 0.1 2.6 7.4 1.0 1.4 1.5 2.2 0.6 7.2 10.4 7.6 0.3 15.0 2.6 0.1 0.1 12.0 16.4 0.2 17.7 8.6 15.0 12.9 10.6 12.1 3.5 17.4 13.6 10.7 27.1 0.5 55.5 6.4 80.0 4.0 6.3 3.1 0.9 8.1 12.2 20.3 23.6 30.5 16.4 26.0 22.3 1.2 1.3 1.8 3.9 7.0 9.2 0.3 6.0 0.2 34.8 19.1 0.3 0.0 9.9 13.3 13.5 6.2 0.2 14.7 42.6 5.9 0.1 47.6 6.7 1.0 28.8 7.3 8.2 10.2 2.2 0.1 3.0 8.6 85.3 7.7 0.1 3.5 1.9 0.0 6.5 0.1 0.5 0.3 0.0 5.1 0.0 0.1 0.0 6.5 0.2 6.7 0.4 0.7 1.5 0.2 0.2 0.2 0.4 0.2 0.7 0.7 0.4 0.6 0.1 1.4 0.3 0.4 12.8 20.1 0.3 1.4 36.1 9.0 8.5 24.5 0.5 21.2 13.7 1.7 0.0 9.2 7.3 0.0 0.2 0.9 141.7 7.9 3.5 0.2 11.9 0.5 1.3 21.7 0.0 0.4 10.9 0.1 5.3 14.3 4.7 7.0 0.2 0.0 0.3 3.4 0.0 0.3 32.8 2.0 7.3 43.4 0.0 0.0 21.2 8.8 1.0 10.4 0.2 0.0 0.5 0.1 22.4 43.3 0.4 10.9 8.3 88.7 32.0 9.0 0.2 0.0 1.1 2.2 0.7 0.3 23.4 40.6 0.3 2.8 0.0 72.4 11.6 VEPH1 "FLJ12604, KIAA1692" ENSG00000197415 "Ventricular zone expressed PH domain containing 1" Q14D04 3 157259742-157533619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 20.2;kidney: 27.0;lung: 29.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 266.0;Alveolar cells type 2: 175.9;Distal tubular cells: 46.9;Early spermatids: 64.5;Late spermatids: 84.7" "Cancer enhanced" "Detected in many" "melanoma: 4.3;renal cancer: 4.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 92.0;hTERT-RPE1: 96.7;HUVEC TERT2: 245.1;TIME: 147.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026645 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli, Cytosol" "HPA026645: AB_1858741" "unprognostic (4.35e-2)" "unprognostic (1.42e-2)" "unprognostic (2.44e-1)" "unprognostic (3.58e-1)" "unprognostic (5.17e-2)" "unprognostic (3.30e-3)" "unprognostic (2.87e-3)" "unprognostic (2.22e-1)" "unprognostic (3.52e-2)" "unprognostic (1.75e-3)" "unprognostic (3.57e-3)" "unprognostic (1.99e-2)" "prognostic favorable (7.75e-9)" "unprognostic (2.03e-1)" "unprognostic (2.57e-1)" "unprognostic (1.15e-4)" "unprognostic (7.49e-2)" 0.4 20.2 0.2 0.1 0.3 2.2 1.9 0.8 0.1 3.1 11.1 0.8 0.7 0.3 17.6 0.0 5.4 0.9 0.2 0.7 0.4 27.0 0.5 29.4 0.0 2.7 1.1 0.2 13.1 2.1 17.1 1.3 2.9 1.4 0.8 0.4 2.5 2.8 0.1 1.5 0.1 0.2 0.4 4.0 0.9 2.9 0.4 0.1 2.0 0.1 0.0 0.4 0.3 0.2 7.3 0.8 16.0 0.0 9.2 33.8 0.0 41.9 92.0 12.2 17.7 1.1 6.4 0.0 16.0 45.3 1.9 0.3 0.5 1.0 67.2 0.2 0.0 7.3 0.8 0.0 2.9 0.0 0.1 9.9 0.7 51.9 10.3 96.7 245.1 0.0 2.5 0.0 33.4 0.9 0.0 0.0 6.6 1.9 6.2 0.0 1.2 0.0 6.1 3.6 0.6 0.0 1.3 1.9 17.0 0.2 70.7 0.1 147.2 48.0 1.6 16.8 58.0 0.0 0.0 0.0 38.6 0.0 11.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.7 0.2 0.3 0.8 0.1 0.7 0.4 2.7 1.1 2.9 0.4 0.4 0.2 0.1 266.0 175.9 1.6 0.5 1.8 0.2 0.0 0.0 0.2 4.5 3.7 0.5 22.8 14.3 31.3 2.1 1.8 0.2 1.2 46.9 6.9 64.5 11.1 0.5 0.9 0.0 0.0 2.8 10.1 0.1 0.9 0.0 4.4 0.0 0.8 0.0 0.0 0.2 0.0 3.3 0.4 0.0 0.0 0.3 84.7 1.5 2.3 28.4 0.0 0.7 1.5 0.0 0.0 0.9 1.8 3.2 0.4 0.0 0.3 0.0 28.7 8.1 0.5 0.0 0.1 1.3 0.3 0.9 0.0 0.4 0.0 0.6 0.9 0.8 0.2 VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 61.9;stomach 1: 97.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 221.7;Gastric mucus-secreting cells: 192.7;Paneth cells: 139.0;Proximal enterocytes: 165.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.0;OE19: 78.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA035675, HPA035676" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA035675: AB_10671223, HPA035676: " "unprognostic (7.86e-3)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (1.35e-4)" "prognostic favorable (1.75e-4)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-3)" "unprognostic (5.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (7.43e-3)" 5.4 3.7 8.7 11.0 9.0 12.6 6.4 6.6 10.6 9.5 6.4 46.8 61.9 5.7 1.5 7.2 6.7 15.7 6.4 8.6 7.8 5.3 1.4 7.7 9.8 8.3 8.4 6.8 3.4 1.2 5.1 4.1 8.0 16.0 26.6 1.2 5.7 4.0 1.2 9.1 61.7 4.1 8.0 11.8 97.5 5.4 8.2 10.2 7.4 1.4 6.3 17.5 7.4 7.2 8.2 0.1 0.2 0.4 2.8 2.2 0.8 2.3 1.9 2.3 2.2 6.1 25.0 3.9 3.5 1.6 0.0 1.9 1.8 0.2 0.5 0.8 0.0 7.3 0.1 0.6 3.4 7.7 9.5 3.3 2.2 2.2 0.0 0.0 4.5 16.1 7.3 2.3 2.6 0.1 12.4 8.7 0.2 78.4 0.0 4.8 0.0 2.0 0.8 9.8 0.1 0.3 0.0 0.5 1.8 0.0 0.7 12.4 2.8 1.0 0.3 3.0 0.0 1.4 3.1 1.2 0.6 10.9 5.0 0.0 3.2 0.0 6.8 2.0 7.4 3.5 4.4 3.9 2.1 4.6 5.6 4.2 0.1 3.4 1.4 3.8 5.8 4.1 8.7 9.0 6.6 10.6 8.6 7.8 8.3 8.4 8.0 8.0 8.2 7.2 4.9 9.6 7.4 10.4 7.2 2.3 5.7 25.5 6.8 0.9 3.3 2.9 1.9 8.6 46.1 0.0 0.0 3.0 13.3 221.7 0.0 3.4 6.2 1.5 2.7 4.5 9.6 6.1 5.5 16.9 3.4 6.7 192.7 1.5 8.2 6.1 5.3 0.3 2.4 1.7 3.0 64.4 14.2 1.9 2.4 19.9 3.7 4.0 1.8 3.7 4.2 28.1 7.2 2.5 1.2 38.7 139.0 2.6 4.4 6.2 165.6 1.6 40.5 0.8 0.0 4.3 7.1 5.4 3.4 3.1 1.4 1.0 8.1 5.6 50.5 33.4 VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 77.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.1;Cone photoreceptor cells: 104.3;Oligodendrocytes: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 22.3;JURKAT: 20.5;THP-1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: AB_2216805, HPA051312: " "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (6.92e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.15e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.75e-2)" "unprognostic (1.48e-2)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (4.34e-2)" 15.7 16.3 2.7 2.2 6.4 0.8 8.5 5.3 4.2 10.3 6.4 6.6 0.5 9.6 3.2 19.2 13.8 2.9 43.7 3.2 5.3 10.6 3.1 10.7 0.7 7.7 5.6 77.5 27.4 19.5 6.5 5.9 5.9 6.6 2.0 12.3 11.6 2.0 26.2 5.3 1.9 6.8 4.0 5.5 9.0 6.0 4.9 0.8 11.6 11.7 1.7 12.5 10.4 9.8 0.1 0.8 14.3 0.4 1.5 0.5 22.3 7.0 2.2 1.7 4.3 3.6 0.3 0.0 6.4 2.8 0.6 0.3 3.4 5.6 4.5 9.7 2.4 0.1 1.6 1.8 1.9 9.2 1.7 1.5 3.3 0.7 0.1 7.6 0.7 20.5 0.0 17.4 1.1 0.9 1.1 1.1 9.9 1.5 0.9 0.1 0.4 0.0 6.4 0.4 2.5 2.4 0.6 0.6 10.4 7.5 0.3 33.3 0.3 2.8 4.5 0.1 3.3 14.1 6.1 2.6 14.7 8.2 0.6 0.0 0.0 6.3 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 2.7 6.4 5.3 4.2 3.2 5.3 7.7 5.6 5.9 4.0 4.9 9.8 4.2 16.0 8.8 1.0 0.1 2.7 1.2 18.7 4.6 23.8 4.3 3.9 78.1 1.5 9.7 5.5 104.3 13.2 1.6 9.8 1.9 11.3 5.7 8.6 6.1 3.6 10.9 0.0 8.3 10.3 29.0 17.2 3.1 19.3 0.0 5.7 2.2 2.8 2.3 11.8 10.9 1.4 24.4 1.0 1.1 2.8 7.8 0.6 10.6 2.8 1.0 3.9 0.0 8.0 39.1 8.6 4.3 10.9 0.5 5.1 0.0 8.0 11.9 32.5 0.0 2.7 9.4 8.2 6.4 5.0 2.0 3.4 1.7 15.9 1.3 6.0 VPS13D "FLJ10619, KIAA0453" ENSG00000048707 "Vacuolar protein sorting 13 homolog D" Q5THJ4 1 12230030-12512047 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.4;Inhibitory neurons: 149.2;Late spermatids: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027332, HPA051621" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" Cytosol "HPA027332: AB_2672223, HPA051621: AB_2681555" "unprognostic (2.97e-1)" "unprognostic (8.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.84e-2)" "unprognostic (9.74e-2)" "unprognostic (1.75e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-3)" "unprognostic (3.33e-1)" "unprognostic (2.00e-2)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "prognostic favorable (7.42e-12)" "unprognostic (5.13e-1)" "unprognostic (1.72e-1)" "unprognostic (4.04e-2)" "unprognostic (8.31e-2)" 10.9 6.9 14.3 4.4 17.2 5.0 10.3 14.5 17.9 13.7 18.1 12.2 3.8 8.1 8.7 12.6 8.9 5.3 21.9 15.8 14.5 10.5 10.4 8.8 6.4 14.6 16.5 8.9 10.9 13.4 7.7 5.3 14.3 17.4 6.4 14.1 10.8 9.3 18.1 24.7 8.7 6.0 13.4 9.3 11.1 6.1 17.8 6.6 15.5 15.3 6.2 9.6 10.6 16.6 9.3 5.2 5.8 4.4 15.1 11.9 2.7 4.4 7.7 7.4 7.0 3.5 6.4 8.7 5.4 12.6 6.2 8.3 10.1 8.7 10.3 4.7 3.4 7.4 8.1 2.8 6.3 10.8 3.7 10.1 11.9 9.5 9.3 9.2 12.0 8.2 15.5 4.3 6.9 4.3 6.4 4.2 2.3 5.0 6.5 5.5 6.9 2.6 5.3 5.4 2.8 3.8 12.9 9.4 9.0 5.4 8.1 3.6 13.1 4.6 4.7 12.0 3.7 3.8 3.3 13.4 5.2 7.5 7.1 3.2 0.7 0.5 1.1 0.7 1.2 0.9 1.2 0.8 0.6 1.6 1.1 0.9 0.9 0.7 0.5 1.5 0.6 0.3 14.3 17.2 14.5 17.9 15.8 14.5 14.6 16.5 14.3 13.4 17.8 16.6 28.9 19.2 23.4 111.0 19.8 21.7 45.1 23.2 19.9 38.1 18.8 12.8 68.0 14.3 35.7 18.4 73.0 8.4 20.3 24.7 3.9 9.1 83.1 20.6 23.5 23.0 14.4 9.4 181.4 14.4 7.2 19.4 28.1 48.1 12.6 26.3 17.9 21.2 11.5 47.1 149.2 15.1 18.3 17.3 15.5 208.7 23.0 17.5 12.4 79.6 16.7 23.0 17.5 78.4 107.4 17.0 11.2 21.8 11.8 32.0 18.2 9.8 32.0 34.1 46.0 23.4 46.5 18.8 12.3 38.2 31.4 14.8 21.4 20.3 15.5 37.3 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024705, HPA024781" Supported Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Centrosome, Cytosol" "HPA024705: AB_10601776, HPA024781: AB_10602100" "unprognostic (8.28e-2)" "unprognostic (1.84e-1)" "unprognostic (9.39e-3)" "unprognostic (3.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.31e-2)" "unprognostic (5.88e-3)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-1)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (2.18e-1)" 18.9 19.4 11.9 14.8 15.1 15.4 18.5 28.7 17.5 21.1 5.0 16.8 20.9 19.4 14.3 20.2 13.7 16.8 36.2 10.1 13.6 25.0 27.8 16.2 14.2 11.2 12.5 18.4 17.5 33.8 12.4 29.7 12.1 20.2 17.2 55.0 12.5 23.2 39.4 14.7 17.5 24.4 10.0 12.3 14.5 32.3 12.2 17.5 18.9 31.2 15.2 25.1 15.0 18.4 17.2 27.3 24.0 21.7 51.8 41.5 25.8 60.8 50.2 53.9 45.9 17.6 16.2 14.6 31.6 48.7 50.1 16.7 27.2 26.4 63.8 15.1 7.8 26.5 13.7 20.2 59.7 11.3 25.1 39.7 50.2 50.4 51.5 38.0 38.7 22.7 20.2 36.8 57.7 11.7 32.0 26.9 23.4 38.2 14.2 15.4 26.5 17.6 45.8 23.4 27.1 14.4 23.8 23.9 37.9 47.1 15.6 22.2 33.4 33.1 16.7 47.6 32.0 12.0 25.0 17.2 37.5 19.9 33.8 34.0 17.2 16.5 13.9 13.1 17.1 10.5 13.4 13.6 13.4 10.8 12.0 14.8 17.6 24.5 12.4 11.8 13.3 14.1 11.9 15.1 28.7 17.5 10.1 13.6 11.2 12.5 12.1 10.0 12.2 18.4 31.8 16.0 15.6 19.6 21.2 39.5 32.7 33.1 18.8 26.4 19.3 13.5 40.7 14.3 25.8 7.3 58.4 36.1 20.5 15.8 37.2 29.3 93.2 20.9 29.0 24.6 18.0 26.1 32.4 15.5 59.2 27.0 15.8 28.4 9.5 16.8 24.3 23.1 44.6 21.9 30.7 16.6 30.5 17.5 22.7 39.6 25.7 25.3 21.4 20.6 22.4 25.8 15.5 24.1 34.0 31.2 13.1 25.9 21.5 50.6 27.8 48.8 18.8 60.2 26.3 21.5 36.6 111.6 43.4 22.5 37.8 113.0 22.7 17.1 14.6 52.6 VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" Nucleoli "HPA039650: AB_10673147, HPA061447: AB_2684521" "unprognostic (2.36e-2)" "unprognostic (7.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.41e-9)" "unprognostic (7.77e-3)" "unprognostic (4.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.18e-1)" 48.5 37.8 19.0 34.9 23.1 60.9 46.6 22.0 30.7 45.6 20.4 55.4 52.9 54.4 7.3 42.5 46.1 20.3 45.3 22.5 15.5 33.7 36.2 34.2 48.6 18.5 18.6 83.8 120.3 37.4 28.6 22.2 20.2 38.1 25.1 20.3 65.5 27.7 84.2 71.2 49.7 22.7 14.3 40.9 70.3 28.4 17.2 46.7 39.7 42.9 32.5 45.2 38.1 21.5 71.8 74.5 35.7 44.4 15.5 38.5 72.1 27.5 53.2 52.6 38.8 55.2 88.7 118.0 76.1 51.4 27.3 60.0 37.9 59.3 19.2 69.6 62.1 72.5 72.6 55.1 51.3 77.1 65.0 66.8 39.9 39.0 32.1 41.6 58.4 55.0 73.6 82.9 21.7 95.1 105.8 83.0 59.8 30.7 61.5 67.5 17.5 150.7 36.2 76.2 61.5 87.8 20.7 110.9 71.8 21.0 93.7 39.1 48.1 35.2 32.0 45.4 39.7 115.7 92.2 68.9 39.9 28.0 26.3 10.6 15.0 15.4 17.9 15.8 21.2 22.4 25.2 27.1 22.1 21.2 23.3 20.7 8.0 30.6 16.0 19.1 17.7 18.3 19.0 23.1 22.0 30.7 22.5 15.5 18.5 18.6 20.2 14.3 17.2 21.5 49.8 19.2 47.7 18.9 77.3 49.1 66.3 46.0 58.6 64.7 76.5 67.8 5.8 44.3 27.8 31.3 29.2 78.4 73.7 156.5 62.6 49.2 77.5 25.6 35.0 46.5 95.8 50.5 21.8 120.5 79.4 38.8 45.9 34.4 37.5 47.3 55.3 52.5 45.5 67.3 24.1 110.0 32.6 54.0 30.6 222.4 53.4 36.1 49.8 15.9 71.3 65.9 89.6 21.6 28.0 51.2 144.4 54.5 66.4 45.1 158.7 75.9 16.1 52.5 26.3 49.3 44.4 40.3 31.4 52.3 54.8 115.3 64.0 61.5 170.5 51.0 VPS53 "FLJ10979, HCCS1" ENSG00000141252 "VPS53 subunit of GARP complex" Q5VIR6 17 508503-721717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 270.0;Late spermatids: 203.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022988, HPA024446" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Cytosol "HPA022988: AB_1848679, HPA024446: AB_1848680" "unprognostic (8.62e-3)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.39e-2)" "unprognostic (9.08e-3)" "unprognostic (3.12e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.53e-2)" "unprognostic (1.82e-2)" "unprognostic (1.89e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.31e-1)" 4.3 4.7 7.0 3.0 5.9 20.5 4.6 21.4 10.3 5.2 2.8 4.5 3.7 4.4 3.4 9.0 4.0 3.6 4.3 8.2 3.3 4.0 4.5 5.1 4.9 3.0 3.9 5.3 4.5 6.4 6.0 4.6 4.2 4.6 5.9 8.1 4.7 5.0 7.0 7.1 4.0 6.1 0.9 4.5 5.0 14.6 4.0 4.9 7.6 5.1 5.2 4.1 4.8 9.4 12.9 26.5 7.6 8.3 12.4 9.5 5.5 6.4 9.4 15.8 15.4 12.6 5.8 7.8 5.9 19.9 10.0 10.9 16.5 13.9 23.1 6.7 11.4 5.0 17.2 8.1 6.1 6.6 9.2 11.1 7.8 14.7 9.8 6.4 11.7 9.7 9.1 9.1 14.9 8.9 4.3 5.1 6.2 5.6 6.9 10.5 3.9 5.2 8.0 10.4 7.6 6.1 12.4 4.3 5.4 7.5 6.5 3.5 7.9 6.8 5.4 12.5 7.0 4.3 3.3 4.8 11.5 5.2 8.6 8.1 1.9 4.4 2.4 2.3 1.8 2.1 2.2 1.7 1.1 3.0 2.3 1.9 6.1 1.9 5.6 3.0 1.9 0.9 7.0 5.9 21.4 10.3 8.2 3.3 3.0 3.9 4.2 0.9 4.0 9.4 16.0 12.8 25.9 54.5 19.3 25.5 16.5 11.6 19.9 53.3 19.6 9.3 17.4 14.3 21.5 40.5 70.9 10.5 19.9 24.9 1.9 16.7 270.0 23.9 22.2 18.7 24.6 5.0 109.3 18.3 7.9 18.5 26.5 28.1 24.1 18.2 15.7 17.7 21.4 63.9 103.6 27.4 4.1 20.6 19.4 203.9 18.6 21.0 10.6 39.4 27.5 18.3 37.0 48.2 62.5 25.3 15.5 23.0 20.6 18.7 21.0 10.6 24.3 52.2 6.6 31.1 20.7 46.0 35.3 24.6 38.8 8.9 26.8 17.2 22.0 19.6 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VTA1 "C6orf55, HSPC228, My012" ENSG00000009844 "Vesicle trafficking 1" Q9NP79 6 142147162-142224685 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030968, HPA030969" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "HPA030968: AB_10602585, HPA030969: AB_2673679" "prognostic unfavorable (7.02e-4)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.17e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.83e-2)" "unprognostic (3.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.96e-1)" "unprognostic (3.24e-1)" 22.2 20.9 16.6 25.7 19.0 30.6 31.6 20.2 20.3 23.2 12.5 34.9 38.2 23.4 25.4 39.1 27.3 23.0 33.9 18.9 18.9 34.5 45.4 21.5 33.4 17.4 18.1 21.0 19.3 28.3 9.9 32.1 17.8 22.5 39.9 29.2 18.2 19.6 55.7 30.7 37.0 26.3 21.1 23.1 23.5 18.3 18.2 45.4 27.6 58.3 39.1 35.8 20.3 22.2 56.5 47.5 75.8 116.8 65.3 71.4 52.3 124.7 74.0 111.6 105.8 80.9 43.0 91.2 82.1 112.6 84.6 70.2 81.5 85.1 153.4 62.3 71.7 99.2 46.2 97.0 48.2 155.6 55.2 59.4 97.7 111.8 71.7 59.8 72.4 69.7 93.7 44.5 94.5 82.1 101.8 80.7 57.0 72.1 53.8 92.1 60.8 55.8 86.4 61.5 79.0 61.5 70.1 53.3 63.7 62.9 57.8 104.4 53.0 50.0 69.6 84.7 90.8 43.5 80.9 103.8 32.7 85.5 77.8 222.4 90.0 151.9 64.3 114.5 83.5 85.6 72.8 76.0 90.9 84.8 79.8 80.4 56.0 97.5 120.3 55.9 79.0 121.5 16.6 19.0 20.2 20.3 18.9 18.9 17.4 18.1 17.8 21.1 18.2 22.2 16.7 22.4 20.3 22.5 25.8 25.2 19.2 25.5 25.6 9.7 16.5 18.3 47.8 12.8 24.5 16.5 0.0 32.7 23.9 40.2 17.6 31.5 4.5 30.7 30.4 17.5 21.6 23.1 40.1 28.0 36.4 25.4 16.8 28.0 12.6 18.1 11.4 24.7 27.9 11.8 38.7 24.7 14.2 20.9 14.3 2.2 11.8 20.0 8.8 40.3 28.0 23.9 35.0 25.6 48.7 30.1 18.3 12.4 16.4 17.2 30.0 31.6 36.6 12.6 6.6 16.8 18.4 23.6 24.9 28.8 31.0 31.7 23.8 25.3 25.9 18.8 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Cone photoreceptor cells: 29.2;Hepatocytes: 16.4;Rod photoreceptor cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.2;Hep G2: 26.3;HSkMC: 13.4;REH: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" 2.8 1.1 0.6 0.1 0.9 1.6 1.5 0.3 1.6 2.9 0.0 0.6 0.3 1.3 0.6 0.9 3.5 0.6 0.8 0.7 0.7 0.5 14.3 0.3 0.2 0.5 1.2 7.9 0.3 0.1 0.6 2.4 0.4 1.0 0.4 0.8 0.9 0.5 0.7 0.7 0.4 0.4 0.0 0.4 0.4 1.8 0.5 2.5 0.8 0.4 0.1 0.6 1.2 0.2 0.0 0.1 1.5 0.2 0.2 1.8 0.6 0.2 2.0 0.0 0.3 7.2 0.0 0.5 0.0 0.4 0.1 0.0 2.3 0.0 0.1 0.4 0.0 0.8 0.0 26.3 1.2 0.0 0.3 13.4 0.6 0.7 0.0 0.1 2.3 3.3 0.2 0.3 0.3 0.1 5.5 0.0 2.2 0.0 0.0 14.0 0.2 0.0 0.1 0.1 0.6 1.0 0.0 0.1 0.7 2.4 0.9 0.0 0.8 0.3 0.3 0.5 0.2 0.2 0.6 1.2 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.3 1.6 0.7 0.7 0.5 1.2 0.4 0.0 0.5 0.2 2.1 3.2 1.7 19.2 0.3 1.8 1.8 3.8 3.4 3.6 1.7 0.5 1.0 1.5 2.3 0.0 29.2 1.0 0.5 0.2 0.0 0.1 0.5 2.9 1.0 5.5 1.8 6.1 7.5 0.5 5.0 2.6 0.0 1.8 3.8 6.5 2.5 16.4 1.2 0.0 5.8 0.1 2.0 3.5 2.4 0.8 6.8 2.6 1.8 2.8 2.3 2.3 1.0 2.5 1.4 0.0 0.0 1.9 0.4 1.1 0.1 0.3 5.4 21.1 0.0 0.9 1.1 1.1 3.4 1.3 2.3 4.4 0.9 7.7 0.3 0.7 WASHC2A "bA56A21.1, bA98I6.1, FAM21A, FAM21B, FLJ10824" ENSG00000099290 "WASH complex subunit 2A" Q641Q2 10 50067888-50133509 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 28.5;Endometrial ciliated cells: 45.7;Respiratory ciliated cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (2.46e-1)" "unprognostic (1.11e-3)" "unprognostic (8.82e-2)" "unprognostic (3.28e-1)" "unprognostic (2.75e-1)" "unprognostic (6.51e-3)" "prognostic unfavorable (6.75e-5)" "unprognostic (4.60e-2)" "unprognostic (2.85e-2)" "unprognostic (2.37e-2)" "unprognostic (9.04e-2)" "unprognostic (2.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.57e-1)" "unprognostic (2.95e-1)" "unprognostic (1.85e-2)" "unprognostic (4.40e-2)" 25.3 25.9 19.9 22.1 20.7 37.5 24.0 23.4 24.8 24.7 18.3 28.9 25.2 22.5 19.2 20.2 19.7 18.0 58.6 19.9 19.9 22.9 15.5 26.0 28.8 21.1 21.2 26.7 17.7 23.3 21.5 22.9 21.1 20.6 28.9 19.9 21.9 20.0 22.3 25.7 28.9 21.2 18.6 26.6 21.5 12.5 22.6 24.2 23.3 15.6 26.9 23.8 22.1 23.9 26.1 12.5 21.1 24.3 83.2 46.0 16.9 29.8 64.0 43.7 46.6 28.8 37.8 22.5 18.1 44.8 41.3 28.0 31.2 25.3 43.2 22.2 22.0 15.9 25.6 29.7 58.6 28.0 27.2 47.8 31.2 47.6 30.5 46.2 33.1 19.2 26.6 22.2 53.9 19.1 15.5 48.0 17.1 16.7 58.4 23.1 30.1 13.7 30.5 29.3 7.3 22.4 27.8 25.9 40.9 30.9 31.6 19.2 49.4 22.0 18.5 62.7 25.0 23.4 48.3 19.1 48.9 51.4 9.0 1.0 9.1 9.9 9.1 11.6 10.1 5.1 8.0 8.8 7.3 4.9 7.7 6.0 4.1 8.2 6.9 4.6 9.2 7.9 19.9 20.7 23.4 24.8 19.9 19.9 21.1 21.2 21.1 18.6 22.6 23.9 16.2 38.5 28.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 10.6 11.0 0.0 0.0 22.9 14.7 0.0 7.4 10.0 0.0 0.0 16.7 0.0 45.7 19.9 7.9 0.0 0.0 0.0 15.6 6.9 8.9 0.0 20.3 15.2 13.5 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 15.1 0.0 0.0 2.6 0.0 0.0 11.7 41.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.7 7.8 9.4 0.0 0.0 WASHC2C "Em:AC012044.3, FAM21C, KIAA0592" ENSG00000172661 "WASH complex subunit 2C" Q9Y4E1 10 45727200-45792964 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 35.2;Collecting duct cells: 23.9;granulocytes: 30.3;Respiratory ciliated cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (7.50e-2)" "unprognostic (2.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-2)" "unprognostic (5.98e-3)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.00e-3)" "unprognostic (1.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-2)" 19.4 15.7 10.9 17.3 11.8 42.5 17.5 14.8 14.9 19.1 13.5 20.3 15.2 16.8 12.4 13.5 14.9 16.5 22.0 11.3 11.4 18.0 15.9 17.7 20.2 12.5 12.2 21.6 11.6 21.4 13.9 13.7 12.7 15.6 22.0 14.2 15.3 14.6 17.1 17.6 19.7 19.0 9.6 19.3 15.0 12.9 14.1 21.2 17.1 9.8 18.7 17.7 14.6 14.0 24.5 25.9 20.7 23.5 52.1 45.8 12.4 28.4 45.8 32.4 30.8 16.0 23.3 20.1 18.8 41.7 30.8 21.6 23.2 13.0 32.6 18.9 19.2 20.9 32.3 12.3 55.0 21.4 24.6 43.4 30.4 35.4 26.1 31.6 33.7 16.5 33.9 15.7 40.1 12.8 14.0 35.9 14.8 14.7 3.9 17.4 30.5 10.5 23.8 38.2 10.0 22.3 32.8 16.1 39.4 21.0 22.1 20.6 58.1 16.8 18.0 44.7 19.1 21.5 36.3 19.6 23.5 49.4 9.2 14.1 17.1 11.7 12.2 17.9 11.8 9.9 10.1 12.7 11.7 9.2 10.0 8.9 16.8 12.5 22.8 8.1 10.4 13.3 10.9 11.8 14.8 14.9 11.3 11.4 12.5 12.2 12.7 9.6 14.1 14.0 16.2 35.3 35.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 11.3 8.8 0.0 0.0 11.8 23.9 0.0 6.8 11.8 0.0 3.9 13.5 0.0 11.3 17.9 6.1 0.0 0.0 0.0 14.0 6.4 7.9 0.0 13.9 30.3 13.7 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 10.3 0.0 0.0 0.0 0.0 11.9 0.0 0.0 3.8 0.0 0.0 12.8 24.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 7.8 7.0 12.1 0.0 0.0 WBP4 "FBP21, MGC117310" ENSG00000120688 "WW domain binding protein 4" O75554 13 41061509-41084006 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038965, HPA058738" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Plasma membrane" "HPA038965: AB_10672836, HPA058738: AB_2683803" "unprognostic (2.56e-1)" "unprognostic (3.69e-3)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (1.76e-3)" "unprognostic (1.54e-2)" "unprognostic (2.13e-2)" "unprognostic (1.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.71e-3)" "unprognostic (2.97e-1)" "unprognostic (2.66e-2)" "unprognostic (8.52e-2)" "unprognostic (7.65e-3)" "prognostic favorable (2.89e-4)" "unprognostic (2.52e-1)" 17.5 16.0 16.1 9.8 16.8 15.6 13.4 16.5 23.9 12.0 13.2 13.2 11.2 18.5 16.0 11.2 11.1 9.3 23.1 16.1 18.1 12.3 16.3 10.4 11.8 16.3 16.6 13.2 8.7 12.4 8.2 11.5 16.4 14.0 9.1 16.5 8.1 14.7 41.0 11.3 11.5 14.8 15.7 9.8 9.3 12.2 16.5 14.7 11.2 29.8 11.6 11.3 11.0 18.6 15.0 9.8 26.7 17.3 17.1 25.9 16.2 33.3 23.4 25.9 19.7 15.5 15.7 21.4 13.0 23.6 31.2 20.6 10.2 16.7 33.0 22.3 14.3 30.2 10.0 16.0 26.3 19.1 18.8 21.3 25.0 18.8 26.5 21.1 22.0 20.3 16.4 9.1 27.5 12.6 27.3 20.6 16.3 23.2 8.0 25.3 16.5 8.4 23.6 14.6 6.1 14.7 10.6 11.3 16.1 21.5 9.4 29.3 19.3 16.0 14.7 22.2 19.5 6.0 7.0 14.7 19.7 13.7 22.2 19.2 13.0 12.4 10.6 12.0 9.7 14.2 13.6 11.5 11.0 12.6 14.4 14.3 27.3 12.5 21.8 18.5 14.4 6.1 16.1 16.8 16.5 23.9 16.1 18.1 16.3 16.6 16.4 15.7 16.5 18.6 42.4 51.3 29.3 21.2 23.9 54.4 60.3 54.8 33.0 46.8 33.5 37.5 110.0 40.0 32.5 25.8 33.3 55.6 23.0 32.3 76.3 52.3 11.9 32.9 58.4 46.9 37.8 111.7 17.0 42.0 61.1 52.2 15.8 44.5 45.7 27.5 38.2 63.1 40.9 45.4 16.6 28.1 18.3 26.7 47.1 9.7 47.8 33.0 32.0 10.3 60.4 63.8 28.8 17.1 33.3 50.3 33.2 52.6 16.8 60.9 33.8 70.6 23.6 49.2 26.3 55.3 66.7 87.5 103.9 29.7 44.9 49.9 22.3 31.9 27.6 40.9 WDFY3 "ALFY, KIAA0993, ZFYVE25" ENSG00000163625 "WD repeat and FYVE domain containing 3" Q8IZQ1 4 84669597-84966690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Developmental protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.9" "Group enriched" "Detected in many" 5 "Astrocytes: 241.0;Excitatory neurons: 231.0;Inhibitory neurons: 248.7;Microglial cells: 209.9;Oligodendrocyte precursor cells: 262.9;Oligodendrocytes: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "TIME: 57.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042734, HPA048572" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nucleoli, Plasma membrane" "HPA042734: AB_2678135, HPA048572: AB_2680447" "unprognostic (7.14e-2)" "unprognostic (6.02e-2)" "unprognostic (7.68e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-2)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" "unprognostic (3.36e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "prognostic favorable (3.64e-5)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.79e-1)" "unprognostic (4.41e-2)" "unprognostic (4.95e-2)" 8.6 8.6 14.8 7.6 31.7 14.4 8.7 26.8 22.9 8.5 4.7 5.7 3.6 8.2 6.4 7.4 8.2 8.8 5.7 16.3 15.6 20.1 5.6 7.4 2.6 30.6 30.4 13.6 9.0 16.3 6.5 11.8 28.7 8.6 5.6 26.2 7.2 7.4 5.9 10.8 4.7 8.5 21.7 7.8 5.6 8.1 25.6 3.4 11.7 13.2 2.3 8.7 5.7 44.9 11.9 7.8 14.3 7.9 24.8 19.3 9.0 11.2 11.8 11.5 10.3 9.1 9.6 0.0 11.3 18.8 12.3 5.9 15.4 12.3 14.6 7.9 4.9 7.5 9.0 5.5 9.4 5.9 13.7 14.2 10.9 15.0 15.1 13.9 37.1 6.0 7.5 35.3 21.4 8.5 5.7 1.4 7.4 11.4 4.0 8.4 11.4 1.8 19.6 15.6 16.8 7.8 13.8 15.1 7.5 13.5 7.9 14.4 57.0 15.1 14.9 8.5 14.1 0.1 0.0 0.0 10.2 5.0 16.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.1 14.8 31.7 26.8 22.9 16.3 15.6 30.6 30.4 28.7 21.7 25.6 44.9 28.5 19.2 12.9 241.0 1.0 14.7 9.1 12.4 11.4 46.6 13.8 11.3 18.2 20.0 14.7 16.5 35.5 11.8 0.5 6.5 1.9 8.6 6.7 27.1 27.8 20.1 9.1 1.3 231.0 7.3 6.9 19.5 15.3 43.4 0.0 31.0 17.9 8.1 20.5 28.6 248.7 7.8 20.3 43.1 14.1 10.1 18.3 29.9 7.2 209.9 19.7 28.7 0.0 262.9 440.4 10.7 6.5 24.5 0.2 13.6 4.8 18.4 15.5 41.9 26.3 30.0 22.8 11.4 7.3 14.1 16.1 14.5 1.8 15.0 6.7 13.6 WDR12 "FLJ10881, YTM1" ENSG00000138442 "WD repeat domain 12" Q9GZL7 2 202874261-203014798 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036389 Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoli "HPA036389: AB_10670716" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "unprognostic (8.17e-2)" "unprognostic (3.59e-3)" "unprognostic (1.24e-2)" "unprognostic (9.40e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (1.52e-1)" "unprognostic (6.14e-2)" "unprognostic (4.78e-2)" "unprognostic (4.58e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.66e-1)" "unprognostic (9.69e-3)" "unprognostic (4.48e-2)" 2.6 3.6 2.1 2.7 2.3 3.6 3.6 2.3 3.2 2.5 1.4 3.0 4.1 3.2 3.2 3.2 3.1 2.3 4.0 2.2 2.9 5.2 4.2 1.7 3.3 2.5 2.1 3.2 2.2 3.5 1.9 2.7 2.7 2.2 4.0 2.6 1.9 2.3 4.8 3.6 2.9 3.4 1.5 2.1 2.3 3.5 2.8 3.2 3.2 6.0 3.7 4.1 2.3 2.5 5.3 5.8 6.4 12.5 12.3 10.4 11.4 7.6 6.6 10.1 9.8 14.8 7.5 10.2 7.2 6.6 8.5 6.6 18.2 13.3 16.0 4.6 11.1 17.0 9.0 17.7 8.0 22.1 9.9 9.5 9.4 12.0 23.6 6.4 10.8 10.2 26.7 5.9 11.3 6.5 14.8 13.3 14.9 7.3 14.3 11.1 9.7 16.1 11.2 6.5 11.4 9.8 6.5 8.2 9.8 11.0 4.7 14.1 8.3 8.3 6.9 7.4 8.4 8.0 12.8 16.3 8.7 15.3 8.8 1.3 1.6 0.6 1.4 1.7 2.0 1.9 1.3 1.4 2.1 1.9 1.7 1.7 0.6 1.3 1.7 2.4 1.6 1.1 2.1 2.3 2.3 3.2 2.2 2.9 2.5 2.1 2.7 1.5 2.8 2.5 10.1 9.6 16.9 12.1 13.6 20.5 21.4 24.4 13.1 10.2 8.4 9.1 27.9 7.2 19.1 5.5 2.1 25.3 7.9 7.8 15.6 18.0 14.3 14.7 25.3 12.6 5.4 22.1 19.2 10.6 34.9 16.5 9.7 13.3 15.2 15.8 8.2 15.0 18.0 15.2 20.3 10.6 24.4 7.2 6.0 8.9 17.1 9.2 1.8 12.2 13.7 6.4 5.2 10.6 9.9 14.2 6.6 15.4 9.3 17.3 13.9 38.1 15.7 8.3 13.1 20.1 41.9 43.0 32.3 18.2 17.3 21.5 10.7 21.0 19.2 17.0 WDR13 ENSG00000101940 "WD repeat domain 13" Q9H1Z4 X 48590042-48608869 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000913 Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA000913: AB_1858795" "unprognostic (5.03e-2)" "unprognostic (6.53e-3)" "unprognostic (3.65e-3)" "unprognostic (2.10e-3)" "unprognostic (3.50e-1)" "unprognostic (1.54e-3)" "unprognostic (3.54e-2)" "unprognostic (6.76e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-1)" "unprognostic (1.58e-2)" "unprognostic (1.33e-1)" "unprognostic (2.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (4.32e-2)" 67.2 76.7 84.2 27.7 81.1 34.6 63.8 68.2 95.2 71.6 85.0 71.6 43.8 71.5 73.7 54.6 67.1 33.4 150.3 85.7 70.4 91.9 106.3 60.8 23.4 73.0 70.2 93.1 189.2 36.9 80.1 29.5 70.5 67.5 26.3 28.2 75.7 45.3 105.2 56.9 54.4 37.5 69.4 58.6 76.6 22.9 74.5 18.7 64.8 83.0 19.6 59.5 56.3 78.5 41.6 59.4 29.3 90.8 39.3 57.4 22.4 28.1 50.7 31.9 29.0 35.5 64.8 28.7 26.3 57.8 25.7 35.0 14.6 61.6 11.3 34.2 26.2 19.7 72.2 65.3 89.3 17.1 51.4 54.7 86.4 45.3 82.7 55.6 44.4 16.3 19.8 35.5 44.9 59.4 23.7 29.9 21.2 18.0 46.6 22.4 31.0 52.3 56.7 32.6 33.9 41.9 31.8 65.2 66.9 20.4 41.9 32.6 74.0 33.0 48.8 52.8 27.5 41.0 16.6 11.0 48.9 25.3 46.5 75.5 42.4 24.7 20.9 47.4 16.7 32.7 21.8 19.9 39.1 25.0 17.4 19.6 29.9 33.0 57.2 24.6 27.0 31.1 84.2 81.1 68.2 95.2 85.7 70.4 73.0 70.2 70.5 69.4 74.5 78.5 61.1 44.8 41.7 19.9 22.3 35.1 72.8 69.1 37.5 45.5 39.2 35.8 79.7 68.6 49.9 20.2 54.2 44.2 19.9 75.5 103.7 89.0 6.1 75.9 36.1 54.0 50.4 31.2 7.8 119.2 34.5 50.5 62.2 53.0 30.4 46.2 65.3 50.2 42.6 33.7 6.6 58.3 50.8 35.4 30.6 20.8 51.6 34.9 58.7 15.0 42.1 68.9 22.6 7.1 14.0 96.8 75.0 43.2 28.3 48.3 90.2 140.7 74.3 55.6 46.0 51.2 59.6 11.2 21.0 29.7 29.8 70.7 21.4 56.2 59.8 65.8 WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.8;Inhibitory neurons: 82.5;Respiratory ciliated cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 45.3;ASC TERT1: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Centrosome, Cytosol" "HPA039616: AB_10796331, HPA058847: AB_2683834" "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favorable (2.70e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" 7.5 8.0 3.1 5.3 2.5 3.7 9.2 5.3 3.8 10.5 10.8 6.8 1.9 16.0 13.3 3.9 20.3 8.4 4.2 2.3 2.5 8.8 6.3 8.8 4.7 5.3 3.6 17.9 5.4 8.1 9.1 6.2 2.9 7.7 4.2 13.0 5.7 8.4 2.3 5.5 4.7 9.1 3.5 4.6 6.2 14.0 2.7 6.9 16.7 2.4 4.9 6.2 6.8 3.6 6.1 5.2 10.3 12.1 45.3 47.0 4.7 7.5 17.2 8.1 10.6 2.8 6.5 10.4 4.1 7.8 17.2 4.0 10.9 5.4 8.6 0.5 8.5 2.2 10.3 6.1 16.1 9.6 2.6 30.5 11.1 11.9 7.2 24.6 10.7 11.0 8.7 9.1 9.9 2.1 7.7 8.1 3.5 3.7 5.6 8.2 10.4 4.2 7.0 2.9 11.5 10.4 10.2 2.4 6.1 13.1 5.5 3.6 7.9 7.9 5.3 17.5 7.8 7.2 7.6 7.6 11.9 3.3 3.7 0.1 0.3 0.2 0.3 0.5 0.3 0.8 0.5 0.6 0.3 1.2 0.5 0.6 0.3 0.8 0.5 0.1 0.3 0.2 3.1 2.5 5.3 3.8 2.3 2.5 5.3 3.6 2.9 3.5 2.7 3.6 5.5 12.8 9.3 26.1 5.4 4.8 4.9 4.6 2.2 10.1 7.3 7.4 4.5 2.8 9.4 18.4 10.4 1.2 1.8 0.7 0.0 5.5 5.1 32.3 14.6 6.7 2.4 4.0 61.8 3.6 3.2 10.8 2.0 12.0 2.5 13.4 4.2 10.0 3.2 25.2 82.5 2.0 12.2 3.2 3.6 3.4 16.4 3.0 1.8 19.7 1.8 6.7 1.0 18.1 19.7 2.9 0.2 18.8 3.9 3.0 0.3 4.0 46.6 21.7 0.0 10.9 7.9 33.8 10.2 3.9 4.7 1.4 2.9 13.1 1.1 1.9 WDR26 "FLJ21016, GID7" ENSG00000162923 "WD repeat domain 26" Q9H7D7 1 224385146-224437033 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028538, HPA028539, HPA061094" Enhanced Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" Mitochondria "HPA028538: , HPA028539: AB_10669752, HPA061094: AB_2684427" "unprognostic (4.09e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-2)" "unprognostic (6.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (8.42e-2)" "unprognostic (6.32e-2)" "unprognostic (5.59e-2)" "unprognostic (4.18e-1)" "prognostic unfavorable (3.31e-6)" "unprognostic (8.40e-3)" "unprognostic (4.00e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" 33.7 28.3 21.9 32.1 21.3 88.9 26.7 20.0 22.0 28.9 27.5 28.9 21.2 26.5 20.8 52.1 22.7 27.1 28.0 23.4 22.8 23.7 35.4 35.1 33.8 21.5 22.0 24.3 24.4 26.4 20.6 35.6 20.2 26.1 25.4 31.5 28.7 25.0 57.1 40.9 26.5 28.6 18.8 38.2 26.7 37.4 22.1 36.0 26.0 45.0 33.2 32.6 31.5 21.9 49.7 28.0 54.6 29.7 76.8 74.6 47.6 58.4 86.4 51.7 48.0 39.0 46.8 51.9 74.4 86.3 21.7 40.6 40.2 47.2 76.1 55.3 53.6 36.2 31.5 31.0 74.7 40.3 68.6 70.8 58.4 55.0 52.1 72.6 80.8 31.7 52.7 51.4 62.4 24.8 42.4 34.7 65.7 41.5 32.0 42.6 66.1 44.2 55.1 48.3 29.5 56.0 64.8 94.9 74.9 55.5 117.5 67.0 88.7 47.7 28.7 41.5 71.3 66.8 33.6 35.2 53.3 26.1 66.8 2.1 1.0 2.1 1.4 1.4 0.8 0.8 0.8 1.0 0.9 0.6 0.7 1.0 4.8 1.5 2.4 1.0 1.1 0.8 21.9 21.3 20.0 22.0 23.4 22.8 21.5 22.0 20.2 18.8 22.1 21.9 32.6 105.8 54.2 55.2 34.4 111.4 29.6 30.9 43.3 24.6 54.1 30.5 49.2 40.0 48.2 35.0 31.3 30.4 54.3 34.8 5.9 22.2 243.3 60.6 35.2 44.2 35.4 53.7 63.4 23.8 15.7 37.9 26.5 71.0 48.1 34.1 41.4 44.2 53.4 38.7 61.3 44.4 40.7 133.4 96.4 102.1 37.0 74.5 46.2 67.5 45.7 16.3 32.0 63.3 70.0 34.2 26.2 28.2 33.0 49.0 19.2 22.8 55.4 24.2 19.7 35.2 41.4 37.1 25.8 63.9 122.3 68.3 45.1 37.9 25.0 63.7 WDR41 FLJ10904 ENSG00000164253 "WD repeat domain 41" Q9HAD4 5 77425970-77620611 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 178.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043124 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA043124: AB_10793990" "unprognostic (1.81e-1)" "unprognostic (9.42e-2)" "unprognostic (2.52e-3)" "unprognostic (9.69e-2)" "unprognostic (1.52e-1)" "unprognostic (4.56e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (1.28e-3)" "unprognostic (1.43e-1)" "unprognostic (1.68e-2)" "unprognostic (2.30e-3)" "unprognostic (1.49e-1)" "unprognostic (4.15e-3)" "unprognostic (6.11e-2)" "unprognostic (4.90e-1)" "unprognostic (1.85e-1)" "unprognostic (2.90e-3)" 16.3 9.4 13.5 13.7 15.1 19.3 15.7 13.3 18.3 13.4 8.5 12.8 8.9 10.9 12.3 19.6 16.6 11.7 17.1 13.8 13.7 12.9 14.8 14.0 15.2 15.0 13.6 7.6 21.0 13.8 6.9 11.4 14.8 11.3 13.1 20.6 12.1 10.9 21.4 12.1 8.8 19.1 12.4 11.8 11.3 27.6 14.0 11.7 22.4 21.0 17.2 14.8 10.8 17.0 17.7 29.8 42.6 62.1 41.9 60.1 32.2 55.5 59.6 26.3 47.5 28.1 28.7 54.1 24.6 53.1 44.4 22.3 31.6 77.8 27.6 65.5 37.1 21.6 32.0 24.7 63.7 46.1 50.0 38.5 96.1 30.1 63.1 28.3 42.0 29.6 21.7 56.8 42.2 39.1 24.7 29.7 15.4 17.8 11.7 58.1 56.1 38.7 27.9 14.8 23.5 29.7 48.2 31.0 47.9 49.9 29.4 57.8 38.2 34.3 28.0 19.1 41.3 51.3 44.8 96.7 48.1 20.7 59.4 25.4 28.5 50.1 11.3 33.8 10.9 19.0 6.5 10.2 51.0 13.3 4.4 8.0 13.7 31.8 38.5 23.2 5.8 16.5 13.5 15.1 13.3 18.3 13.8 13.7 15.0 13.6 14.8 12.4 14.0 17.0 10.2 38.5 12.3 63.3 12.6 12.0 25.2 31.0 14.2 34.8 11.6 12.3 17.3 12.8 16.5 18.4 20.9 8.8 16.4 4.4 37.2 22.7 178.8 17.7 25.6 11.3 6.0 13.5 41.3 20.9 25.5 23.7 9.2 8.3 15.8 11.7 8.9 11.5 26.3 23.5 46.7 8.5 14.2 20.2 29.5 87.5 9.6 23.9 17.8 36.5 16.4 14.9 15.5 56.8 78.9 15.2 7.4 8.2 25.6 26.8 5.0 18.7 17.0 19.2 6.6 12.7 22.3 56.4 44.5 23.9 14.2 6.3 11.4 35.5 10.9 28.0 WDR45B "WDR45L, WIPI3" ENSG00000141580 "WD repeat domain 45B" Q5MNZ6 17 82614562-82648553 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 462.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017886 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA017886: AB_1858810" "unprognostic (1.91e-1)" "unprognostic (7.77e-2)" "unprognostic (5.13e-2)" "unprognostic (3.78e-2)" "unprognostic (1.42e-1)" "unprognostic (3.88e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (1.22e-2)" "unprognostic (4.41e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-2)" "unprognostic (9.93e-3)" "unprognostic (8.89e-2)" "unprognostic (4.27e-2)" "unprognostic (1.02e-1)" 39.4 44.5 50.7 22.4 56.1 58.7 37.6 52.4 50.4 35.6 41.4 33.6 30.8 37.9 30.1 59.3 43.6 36.8 37.0 48.9 50.9 37.3 32.4 32.9 23.3 53.0 51.7 50.1 46.1 46.2 36.8 25.5 50.7 37.5 25.9 30.9 46.6 28.5 24.4 46.9 34.4 27.5 54.3 28.6 39.9 50.0 54.6 23.8 32.1 26.8 25.8 39.8 40.1 60.3 100.5 65.1 56.0 54.6 53.8 44.4 63.0 71.1 77.7 106.4 93.5 78.7 53.8 27.9 44.8 64.2 76.9 52.4 52.8 58.5 101.4 18.6 93.7 55.4 40.5 67.8 64.1 42.8 42.8 50.9 61.7 62.1 57.3 52.1 88.2 38.0 41.6 27.8 63.0 66.8 31.3 37.6 72.3 86.8 78.2 36.6 92.0 28.1 65.0 99.3 68.3 100.9 66.9 74.7 90.7 67.6 86.9 39.2 63.6 120.0 94.4 81.5 135.8 66.5 29.7 40.5 76.8 42.9 87.0 34.2 27.5 33.9 16.4 27.6 16.6 13.4 12.5 13.7 22.2 12.8 10.9 10.5 21.9 13.9 22.8 10.9 11.3 19.3 50.7 56.1 52.4 50.4 48.9 50.9 53.0 51.7 50.7 54.3 54.6 60.3 62.1 32.1 47.3 17.0 51.5 59.9 48.6 71.5 48.3 39.7 76.3 54.0 21.2 60.1 84.4 42.3 12.5 54.4 49.6 85.6 88.0 128.8 152.7 145.2 72.5 56.1 47.4 14.5 16.9 137.7 77.3 44.9 43.3 177.1 73.5 32.7 47.2 71.5 45.8 45.4 20.0 68.0 67.1 62.0 42.5 462.7 57.2 72.8 56.9 15.9 57.8 66.2 44.3 13.0 24.6 157.6 55.4 48.2 24.8 72.8 58.3 71.5 91.1 34.9 32.9 44.6 53.2 94.5 171.6 53.8 72.5 108.1 46.7 37.0 68.3 101.0 WDR49 FLJ33620 ENSG00000174776 "WD repeat domain 49" Q8IV35 3 167478684-167653983 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 31.3;choroid plexus: 29.3;fallopian tube: 10.0" "Group enriched" "Detected in some" 5 "Astrocytes: 79.0;Endometrial ciliated cells: 43.4;Respiratory ciliated cells: 47.7" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 2.7;myeloid DC: 2.2;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 24 "dendritic cells: 2.9;monocytes: 2.7" "Cell line enhanced" "Detected in some" "AF22: 2.7;NTERA-2: 3.0;THP-1: 14.5;U-937: 7.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 9.5" "HPA036225, HPA036226" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA036225: AB_10696652, HPA036226: AB_2675007" "unprognostic (1.68e-3)" "unprognostic (1.24e-3)" "unprognostic (2.48e-2)" "unprognostic (1.96e-1)" "unprognostic (5.67e-2)" "unprognostic (5.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.02e-2)" "unprognostic (9.28e-3)" "unprognostic (1.34e-1)" "unprognostic (4.60e-9)" "unprognostic (1.79e-4)" "unprognostic (3.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.07e-1)" 0.1 0.1 10.2 0.4 8.2 2.0 0.1 16.6 3.4 0.3 29.3 0.1 2.0 0.4 0.0 0.9 10.0 0.2 2.1 7.0 15.6 0.3 0.0 1.9 0.3 30.1 27.0 0.1 0.3 0.0 0.5 0.0 23.8 0.2 0.1 0.0 0.2 0.0 0.0 0.1 4.6 0.1 31.3 0.4 0.2 0.6 15.5 0.4 0.0 0.2 0.3 0.2 0.2 23.4 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 2.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.5 10.2 8.2 16.6 3.4 7.0 15.6 30.1 27.0 23.8 31.3 15.5 23.4 0.2 0.0 0.6 79.0 0.1 0.0 0.9 1.7 9.1 0.0 0.1 0.1 1.1 0.0 10.9 0.0 0.0 0.0 1.6 0.1 0.0 0.1 2.4 43.4 0.3 0.2 0.0 1.7 4.5 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 4.1 1.6 2.5 0.8 0.0 1.8 0.0 0.0 4.0 0.0 0.0 2.5 3.0 0.0 0.0 0.0 0.1 0.4 3.3 0.0 47.7 0.0 6.6 0.3 0.6 0.1 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.8 WDR77 "MEP50, p44" ENSG00000116455 "WD repeat domain 77" Q9BQA1 1 111439890-111449256 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 104.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026437, HPA026448, HPA027271" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 18000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA026437: AB_10600199, HPA026448: AB_10600993, HPA027271: AB_10602004" "unprognostic (1.84e-1)" "unprognostic (7.01e-2)" "unprognostic (6.26e-3)" "unprognostic (1.19e-3)" "unprognostic (1.12e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (5.14e-1)" "unprognostic (3.88e-3)" "prognostic favorable (7.88e-4)" "unprognostic (6.16e-2)" "unprognostic (1.72e-3)" "unprognostic (1.63e-2)" "unprognostic (8.13e-2)" "unprognostic (1.92e-1)" "unprognostic (6.17e-2)" "unprognostic (1.23e-2)" 16.5 23.5 13.5 18.2 13.6 10.3 14.1 13.0 13.5 14.2 13.3 17.0 14.9 20.1 17.7 27.3 104.9 12.4 29.6 15.1 14.6 19.5 22.7 13.8 28.4 14.1 15.2 12.6 17.5 18.2 14.2 18.5 14.2 17.4 24.1 11.4 19.4 14.7 42.2 13.6 16.3 19.2 13.4 22.5 21.2 14.1 15.1 20.5 13.6 32.9 36.2 24.6 16.7 14.1 70.0 58.6 56.0 46.2 32.5 19.6 76.6 51.8 27.6 76.4 50.1 86.0 25.5 118.8 48.6 44.0 49.1 49.4 101.2 96.9 91.1 46.9 80.0 70.9 67.4 125.2 36.9 71.7 114.6 23.8 68.6 75.4 47.6 20.5 51.7 51.9 96.3 30.1 74.5 86.0 94.0 38.8 109.7 64.5 99.4 92.2 88.2 44.9 68.9 118.7 45.6 33.4 45.5 54.7 42.3 70.6 45.1 50.5 38.7 42.3 86.4 82.6 111.1 25.4 34.1 106.3 54.6 81.1 126.5 17.6 24.6 6.6 27.5 38.2 31.2 53.6 30.0 31.5 54.5 42.3 31.2 29.4 3.6 58.5 35.6 34.1 27.8 27.1 13.5 13.6 13.0 13.5 15.1 14.6 14.1 15.2 14.2 13.4 15.1 14.1 11.1 12.8 11.4 8.1 29.6 20.8 27.9 34.8 10.8 11.5 13.2 11.7 22.2 10.0 17.7 18.4 25.0 56.1 19.4 7.0 25.4 30.6 4.8 42.1 18.2 15.3 15.7 18.1 6.0 13.6 57.0 12.9 26.5 40.9 15.8 21.2 8.2 15.6 47.4 8.4 7.2 14.4 20.3 20.3 8.0 4.1 7.5 18.9 5.4 7.5 16.0 9.7 13.4 7.1 5.8 22.1 7.8 9.1 20.1 28.2 8.8 29.3 34.2 9.2 13.1 10.6 18.3 22.3 24.8 26.1 18.5 45.6 15.3 36.0 22.5 23.5 WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" 17.7 16.2 4.5 4.6 5.4 4.9 16.9 4.6 6.3 18.2 6.6 11.5 4.8 18.9 2.4 9.9 17.4 1.6 10.9 4.3 4.4 11.9 32.8 13.7 5.6 5.9 5.1 21.4 11.0 2.4 13.1 3.9 5.3 16.0 1.7 0.8 11.0 5.9 18.2 18.4 17.8 5.1 4.7 24.3 11.0 7.5 6.1 6.6 10.5 2.1 4.2 15.4 13.7 6.4 0.7 12.3 1.7 9.1 12.4 7.0 9.2 0.9 0.2 0.6 0.0 1.8 4.4 4.9 6.5 5.4 6.2 12.2 6.3 8.4 0.4 9.5 12.8 0.3 8.8 5.9 22.1 4.1 7.6 17.8 8.8 5.9 4.1 1.9 5.0 3.7 1.0 6.3 7.6 6.8 1.3 7.6 3.9 4.2 9.4 6.4 2.9 6.8 3.7 2.0 2.2 5.0 4.3 3.4 15.4 0.1 6.0 6.1 6.8 4.8 5.4 7.9 6.7 0.5 1.3 3.1 7.7 5.9 2.4 0.0 1.4 2.8 1.1 2.3 1.3 1.3 1.2 1.2 1.8 1.0 0.8 1.1 0.3 2.1 2.3 3.3 1.2 1.1 4.5 5.4 4.6 6.3 4.3 4.4 5.9 5.1 5.3 4.7 6.1 6.4 6.3 12.8 10.3 6.5 4.2 2.5 2.9 4.4 8.6 4.5 4.8 5.3 3.6 4.3 3.8 0.0 4.2 2.5 9.9 6.8 1.9 3.1 0.7 2.1 6.2 5.4 1.2 14.3 5.3 4.5 1.9 8.2 6.6 2.9 4.5 6.2 4.6 27.7 23.8 5.0 5.3 4.6 10.2 22.3 4.5 1.2 16.4 15.3 0.0 9.4 7.5 2.5 9.2 5.0 7.6 4.8 4.8 15.1 5.3 2.9 8.7 20.1 6.4 1.8 19.7 5.9 4.5 0.7 2.0 3.4 1.7 2.3 4.7 5.8 4.4 1.7 WDR83 MORG1 ENSG00000123154 "WD repeat domain 83" Q9BRX9 19 12666802-12675832 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042629, HPA042838" Uncertain Approved "Nucleoplasm,Vesicles,Centriolar satellite" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Centriolar satellite" "HPA042629: AB_10794763, HPA042838: AB_10794173" "unprognostic (1.12e-2)" "unprognostic (3.15e-3)" "unprognostic (1.43e-3)" "unprognostic (1.34e-2)" "unprognostic (1.36e-1)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (3.60e-3)" "unprognostic (2.52e-1)" "unprognostic (1.56e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.30e-2)" "unprognostic (4.07e-2)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "prognostic favorable (3.12e-4)" 5.2 6.7 7.5 3.4 8.1 5.3 5.2 8.0 9.3 6.0 7.1 7.1 2.6 6.2 2.0 4.2 6.8 2.9 7.2 7.5 7.9 6.9 4.8 4.6 5.0 7.8 7.8 6.5 6.3 5.6 5.7 2.7 7.7 5.9 1.4 2.5 8.1 3.3 4.2 6.5 4.6 1.9 7.5 5.3 6.9 10.0 7.8 6.8 5.8 2.9 3.1 5.7 4.5 8.2 6.8 11.0 6.2 8.1 11.0 4.4 4.9 6.1 5.8 7.3 7.5 13.4 5.7 10.0 8.7 5.6 4.2 7.0 7.3 9.6 1.3 10.2 16.0 8.0 7.6 8.0 9.3 11.3 8.4 8.0 7.6 6.0 4.9 5.1 7.2 21.6 7.2 0.8 3.4 25.6 16.4 9.2 4.8 8.0 18.8 10.9 7.7 9.3 7.1 8.0 12.6 8.6 6.4 9.0 5.3 3.5 5.1 11.2 4.0 8.0 2.4 6.2 6.1 24.7 17.7 4.9 12.7 8.7 4.6 5.6 13.4 5.7 10.2 12.4 12.2 9.7 10.2 10.2 14.0 10.8 9.8 12.8 6.7 21.9 6.4 23.5 12.2 10.8 7.5 8.1 8.0 9.3 7.5 7.9 7.8 7.8 7.7 7.5 7.8 8.2 10.8 0.0 14.4 4.2 13.5 15.4 12.1 15.9 11.4 21.1 10.1 9.8 4.4 17.2 12.0 18.4 12.5 12.4 22.3 9.0 17.6 15.6 17.8 12.2 7.3 12.0 9.6 16.2 7.2 17.5 13.9 9.9 9.2 6.1 14.0 12.4 8.6 9.2 13.2 20.2 7.1 7.8 16.2 11.6 19.2 61.9 15.8 9.6 16.0 1.9 17.8 18.2 24.7 4.5 4.4 13.5 5.8 18.0 11.6 15.4 13.6 33.7 18.4 22.7 19.7 8.1 11.3 25.8 17.6 8.3 16.1 9.0 12.4 10.1 9.6 14.6 WDSUB1 "FLJ36175, UBOX6, WDSAM1" ENSG00000196151 "WD repeat, sterile alpha motif and U-box domain containing 1" Q8N9V3 2 159235798-159286703 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036840, HPA058172" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "Nucleoplasm, Cytosol" "HPA036840: AB_10670926, HPA058172: AB_2683628" "unprognostic (1.37e-2)" "prognostic favorable (3.35e-4)" "unprognostic (2.56e-1)" "unprognostic (7.33e-3)" "unprognostic (3.44e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.76e-3)" "unprognostic (4.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" "unprognostic (6.75e-2)" "unprognostic (3.46e-3)" "unprognostic (8.49e-2)" "unprognostic (1.72e-1)" "unprognostic (1.00e-2)" "unprognostic (2.87e-2)" 6.7 10.9 9.1 4.6 10.2 10.6 12.0 10.7 12.0 7.8 11.7 6.7 4.9 8.2 17.5 7.5 9.8 5.9 10.1 8.9 9.3 23.5 6.9 9.0 7.9 9.7 9.3 13.5 10.6 13.9 9.1 9.7 9.8 9.1 7.6 11.1 10.4 6.8 6.7 6.9 5.8 6.6 8.9 8.6 7.4 6.7 9.4 7.0 17.3 6.5 5.8 6.2 6.3 11.7 8.4 6.3 5.4 9.0 10.1 11.4 19.1 6.7 13.0 11.4 20.4 13.7 13.6 11.7 6.9 9.9 20.3 5.2 15.9 5.9 16.1 4.5 13.4 12.1 6.8 14.0 12.2 10.2 15.6 6.7 21.5 14.4 12.0 22.2 9.8 14.9 16.0 8.5 11.1 8.8 7.3 18.5 7.5 14.3 13.6 11.3 8.3 6.2 13.6 12.2 10.3 6.8 7.0 8.6 15.9 26.0 6.7 17.3 4.1 8.2 6.2 11.8 6.5 4.2 7.7 10.7 14.4 12.6 5.3 3.9 11.1 3.5 14.3 8.6 10.9 11.8 5.6 9.1 12.2 9.9 6.7 8.0 0.8 20.8 7.9 11.6 3.3 7.8 9.1 10.2 10.7 12.0 8.9 9.3 9.7 9.3 9.8 8.9 9.4 11.7 8.2 12.8 6.8 28.4 10.7 5.4 8.7 13.0 11.4 6.9 9.3 8.0 11.3 10.0 11.3 20.2 2.1 25.4 11.2 5.1 35.2 9.5 4.5 13.7 6.9 7.0 5.4 6.7 42.4 3.6 9.2 9.9 10.2 16.1 12.0 13.2 6.4 2.0 17.3 5.0 52.0 4.5 12.2 14.8 4.8 2.9 12.8 10.2 5.4 29.0 9.2 6.6 14.4 31.7 34.6 4.0 7.0 11.3 3.8 6.8 6.9 23.7 15.0 9.7 0.0 12.0 7.8 10.1 22.5 11.1 6.3 23.0 9.1 12.7 7.1 7.3 WIPI1 "ATG18, ATG18A, FLJ10055, WIPI49" ENSG00000070540 "WD repeat domain, phosphoinositide interacting 1" Q5MNZ9 17 68420948-68457513 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 127.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 165.7;Syncytiotrophoblasts: 125.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 114.1;eosinophil: 223.6" "Lineage enriched" "Detected in all" 9 "granulocytes: 223.6" "Cell line enhanced" "Detected in many" "ASC diff: 224.3;HHSteC: 216.7;HSkMC: 180.8;SK-MEL-30: 183.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007493, CAB037230" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB037230: AB_1841265, HPA007493: AB_1848642" "unprognostic (2.83e-2)" "unprognostic (7.85e-2)" "unprognostic (1.05e-3)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-2)" "unprognostic (3.97e-3)" "unprognostic (1.78e-2)" "prognostic favorable (3.11e-4)" "unprognostic (2.86e-1)" "unprognostic (1.79e-1)" "unprognostic (3.06e-1)" "unprognostic (6.32e-3)" "unprognostic (6.56e-2)" "unprognostic (4.99e-2)" "unprognostic (1.78e-1)" "unprognostic (1.89e-3)" 31.3 18.8 11.2 14.1 11.2 26.6 30.5 12.5 15.1 33.1 19.1 36.4 12.8 15.3 14.4 14.8 12.6 23.3 78.4 10.6 12.9 33.3 18.7 26.2 8.7 12.5 12.0 11.2 29.8 25.2 17.8 62.4 12.5 17.4 38.5 8.2 55.0 18.3 127.2 21.9 14.8 18.8 11.4 12.5 29.3 9.6 15.5 5.9 21.1 97.5 16.7 22.0 14.4 11.9 4.9 9.8 8.6 12.5 224.3 167.2 49.0 36.3 163.5 13.7 43.6 7.2 7.3 3.0 16.0 74.2 47.9 3.7 3.3 22.1 23.9 4.4 4.6 34.7 3.2 42.6 216.7 2.4 48.5 180.8 39.5 54.2 72.0 44.2 61.3 5.3 2.5 82.0 41.1 29.9 0.5 7.1 1.8 12.7 15.0 0.4 30.3 35.7 20.2 16.7 2.4 11.4 7.7 103.8 183.4 44.4 54.8 9.5 61.2 65.4 10.1 31.0 8.6 78.2 92.0 10.5 98.9 16.5 29.7 114.1 18.4 223.6 11.9 22.7 5.3 4.4 3.1 11.7 9.0 1.4 0.2 5.6 39.0 10.7 24.7 6.3 2.7 15.0 11.2 11.2 12.5 15.1 10.6 12.9 12.5 12.0 12.5 11.4 15.5 11.9 26.2 9.6 11.5 12.7 13.3 7.8 11.9 45.6 0.6 15.0 24.1 8.9 7.3 28.6 48.5 16.5 2.1 44.0 18.3 30.2 31.3 31.2 6.3 26.3 19.9 17.2 12.0 56.6 9.4 57.2 165.7 41.2 25.5 40.0 7.0 12.3 33.9 11.7 35.6 10.1 8.2 67.6 44.7 18.2 14.5 5.2 46.3 37.1 42.7 20.6 34.2 10.6 20.6 6.0 12.2 28.8 20.1 42.2 83.3 55.3 8.5 71.8 49.6 15.7 26.3 10.1 24.1 5.0 5.1 3.3 6.8 125.1 13.6 27.8 28.2 36.7 WRAP53 "FLJ10385, TCAB1, WDR79" ENSG00000141499 "WD repeat containing antisense to TP53" Q9BUR4 17 7686071-7703502 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Chaperone, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 29.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023026, HPA028130, HPA029928" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA023026: AB_10963931, HPA028130: AB_10961728, HPA029928: AB_2673257" "unprognostic (1.45e-1)" "unprognostic (3.50e-3)" "unprognostic (6.81e-2)" "unprognostic (2.53e-3)" "unprognostic (3.86e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (4.70e-4)" "unprognostic (8.69e-2)" "unprognostic (3.29e-1)" "unprognostic (1.41e-1)" "prognostic favorable (8.26e-4)" "unprognostic (2.68e-2)" "unprognostic (5.67e-2)" "unprognostic (7.23e-2)" "unprognostic (2.47e-1)" "unprognostic (2.93e-2)" "unprognostic (4.04e-1)" 4.1 3.7 3.4 4.5 3.5 7.6 4.0 3.4 3.5 4.3 5.0 4.2 2.7 4.5 2.3 4.5 14.5 3.0 4.2 3.4 3.5 4.0 3.6 4.1 6.9 3.9 5.0 3.3 4.5 3.1 4.1 3.4 3.8 3.0 3.5 3.4 3.6 3.0 6.2 4.4 4.7 3.9 4.0 6.9 4.3 5.2 3.5 8.0 3.5 4.5 6.5 3.8 3.6 4.0 22.7 40.6 28.9 29.5 9.2 8.0 16.5 14.3 14.9 45.6 42.1 24.2 13.2 23.3 15.0 13.1 18.7 24.0 33.8 24.5 35.2 14.4 41.4 12.0 22.6 20.5 7.9 8.1 14.7 6.8 9.3 39.9 8.9 6.8 28.8 27.4 12.0 7.7 18.7 21.1 27.0 22.2 15.4 16.7 20.5 35.0 19.3 14.0 17.2 7.7 13.3 19.4 23.1 11.9 12.1 14.0 16.7 10.3 10.1 17.4 19.0 0.1 36.6 5.3 15.9 13.1 16.8 15.2 21.4 29.4 5.8 5.0 5.3 6.3 6.1 3.0 4.2 6.2 5.3 4.2 3.8 4.2 2.5 5.0 2.8 7.4 8.9 3.8 3.4 3.5 3.4 3.5 3.4 3.5 3.9 5.0 3.8 4.0 3.5 4.0 4.6 3.2 3.4 2.3 7.0 3.8 5.2 12.9 2.8 5.6 4.1 4.6 3.6 2.8 7.0 11.0 6.2 12.3 9.2 4.5 3.9 10.1 3.9 22.4 3.4 5.8 3.0 10.8 2.0 10.4 17.0 4.4 4.1 4.1 1.3 7.3 5.3 4.6 7.7 1.7 2.1 5.6 18.3 7.2 3.1 1.9 2.5 5.4 3.6 1.0 8.7 7.2 12.3 5.0 2.8 6.9 3.7 2.2 8.8 2.2 5.2 6.5 51.0 6.3 0.0 6.4 6.3 13.3 6.7 3.5 4.5 4.1 5.7 5.8 7.2 2.9 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 171.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 33.6 22.1 16.3 25.8 21.5 18.2 40.6 19.6 16.3 23.6 24.3 26.9 26.3 23.0 24.6 33.1 18.5 45.3 50.8 14.3 20.7 40.9 111.7 27.2 39.0 18.3 19.0 24.7 28.0 116.3 9.8 36.9 19.7 33.4 33.1 43.2 25.9 25.6 171.4 40.8 28.1 24.6 18.1 45.7 34.3 29.5 19.5 22.7 32.6 122.2 30.6 33.7 15.8 23.1 59.8 27.1 18.3 13.1 23.0 22.4 16.3 21.0 22.5 16.5 19.5 18.9 35.3 24.9 14.0 36.5 22.9 49.3 26.4 34.1 28.5 31.6 21.0 28.7 24.4 44.7 16.8 11.7 14.0 20.5 42.5 18.2 33.3 25.3 74.1 29.0 14.3 28.7 28.4 29.6 27.7 8.1 11.2 82.6 30.0 18.0 21.4 22.5 37.3 44.5 5.5 12.9 21.2 104.7 23.0 39.8 31.3 10.8 84.4 23.9 28.7 26.3 10.7 33.9 22.0 25.7 29.9 1.6 19.0 6.2 2.1 3.9 5.2 1.9 4.6 2.7 6.4 5.3 1.5 2.4 7.5 4.7 1.3 2.4 2.2 1.9 6.5 2.0 16.3 21.5 19.6 16.3 14.3 20.7 18.3 19.0 19.7 18.1 19.5 23.1 51.2 25.6 22.6 29.0 13.0 35.8 26.9 15.4 26.7 28.8 41.7 23.5 82.7 44.3 19.2 29.5 58.4 28.3 19.5 23.7 43.0 20.5 42.1 22.6 20.1 32.3 23.6 3.0 55.3 37.6 3.3 27.6 35.2 35.5 3.8 18.0 62.4 88.8 55.9 40.4 134.6 25.3 14.2 95.2 28.1 12.7 32.3 43.0 30.2 61.8 18.6 23.3 18.6 60.3 103.8 45.1 16.0 36.5 18.5 45.1 15.8 45.7 17.2 52.6 6.6 18.8 16.6 12.4 21.2 28.8 39.5 23.0 32.0 25.1 19.7 38.3 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 XIAP "API3, BIRC4, hILP, ILP-1" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913976 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: AB_2677993" "prognostic unfavorable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 9.2 7.7 6.5 9.2 7.5 8.3 9.7 6.8 7.0 9.6 12.9 12.4 10.1 8.4 10.0 11.5 7.4 8.6 7.8 5.8 8.2 11.8 12.1 8.5 10.4 7.6 8.1 7.5 8.3 18.4 6.3 8.6 7.3 8.5 10.1 21.4 8.6 7.4 10.3 8.8 10.1 7.4 8.5 10.4 10.2 4.2 8.1 8.9 14.9 11.9 8.6 9.6 6.1 10.3 15.8 13.2 10.2 8.8 11.8 15.0 13.3 16.9 12.4 8.9 7.7 5.9 17.9 14.7 24.3 14.4 17.1 5.6 15.3 10.5 16.3 15.5 8.3 9.9 11.1 9.2 14.9 18.1 19.7 10.4 16.0 14.9 19.0 10.2 12.7 10.8 15.9 16.4 17.6 16.5 10.2 8.8 8.4 15.6 10.3 10.8 11.9 15.6 13.4 22.6 6.8 10.0 22.9 13.0 13.5 9.0 8.0 8.7 15.7 0.5 6.0 27.0 18.9 13.8 14.9 15.8 18.3 12.7 11.5 9.3 1.8 2.6 3.3 1.5 3.0 3.1 2.4 3.6 1.0 4.0 2.7 1.9 5.6 2.4 2.9 2.9 1.8 1.5 6.5 7.5 6.8 7.0 5.8 8.2 7.6 8.1 7.3 8.5 8.1 10.3 50.0 80.1 91.6 26.4 42.1 26.6 36.3 35.0 28.5 72.1 29.7 19.9 44.5 44.3 55.2 53.3 95.9 17.9 41.7 122.9 27.4 36.0 2.7 38.4 44.9 55.0 47.4 23.5 30.0 54.0 30.0 38.4 39.8 50.4 60.7 30.9 64.2 85.8 29.0 75.7 34.9 62.2 26.4 43.6 33.0 4.1 42.6 44.2 8.8 29.0 45.8 45.8 55.6 32.6 41.9 65.4 53.5 51.6 39.5 53.0 59.2 59.8 50.6 133.7 65.7 43.6 34.9 15.2 21.0 30.8 35.5 38.0 40.8 30.0 48.0 68.1 XIRP1 "CMYA1, DKFZp451D042, Xin" ENSG00000168334 "Xin actin binding repeat containing 1" Q702N8 3 39183210-39192596 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 682.0;skeletal muscle: 383.4" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 850.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Region enhanced" "Detected in some" "cerebellum: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 4.4;LHCN-M2: 1.1;RH-30: 3.0" "Not detected" "Not detected" "HPA016750, HPA018458, CAB026391" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" Nucleoplasm "CAB026391: , HPA016750: AB_1858884, HPA018458: AB_1858885" "unprognostic (2.19e-1)" "unprognostic (6.40e-2)" "unprognostic (1.13e-1)" "unprognostic (9.75e-2)" "unprognostic (2.76e-1)" "unprognostic (2.43e-2)" "unprognostic (4.94e-2)" "unprognostic (2.66e-3)" "unprognostic (1.66e-3)" "unprognostic (1.46e-1)" "unprognostic (5.30e-2)" "unprognostic (6.26e-2)" "unprognostic (1.02e-5)" "unprognostic (2.08e-2)" "unprognostic (2.78e-2)" "unprognostic (6.86e-4)" "unprognostic (4.12e-2)" 1.1 0.3 0.0 1.2 0.0 0.0 0.2 2.0 0.3 0.0 0.1 0.7 0.0 0.2 0.0 5.6 0.0 1.0 682.0 1.1 0.1 0.1 0.1 1.7 0.0 0.6 0.2 0.1 1.2 0.0 0.5 0.7 0.2 3.4 0.0 0.0 5.1 0.0 383.4 0.5 0.5 0.4 0.2 0.6 0.3 0.0 0.1 0.5 0.2 96.4 0.0 3.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 1.1 0.1 0.6 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 850.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;intestine: 12.2;stomach 1: 11.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 26.7;Erythroid cells: 63.5;Gastric mucus-secreting cells: 17.9;Proximal enterocytes: 21.5;Undifferentiated cells: 14.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 102 "granulocytes: 10.2" "Cell line enhanced" "Detected in many" "HEL: 44.4;HL-60: 23.2;K-562: 29.1;NB-4: 21.1;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: AB_1846286" "unprognostic (2.37e-2)" "unprognostic (7.13e-3)" "unprognostic (5.03e-2)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "unprognostic (4.56e-1)" "unprognostic (3.59e-2)" "unprognostic (4.00e-2)" "unprognostic (4.77e-3)" "unprognostic (5.07e-2)" "unprognostic (6.63e-2)" "unprognostic (5.90e-2)" "unprognostic (4.44e-8)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" 0.2 2.1 2.5 1.4 2.5 14.2 0.7 2.3 3.0 1.2 0.2 12.2 10.8 0.7 0.5 2.0 3.8 0.9 4.3 3.2 4.9 0.9 0.8 1.0 0.2 1.6 0.9 0.7 4.9 0.7 1.3 0.7 2.0 1.5 11.2 2.1 1.2 0.9 5.4 0.7 10.6 1.8 0.5 0.5 11.5 1.4 2.8 0.2 0.9 5.8 0.5 1.1 0.8 1.4 17.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 14.7 0.3 0.0 0.8 2.7 15.4 0.1 0.0 0.0 4.2 44.4 2.4 0.0 0.0 23.2 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 29.1 10.9 0.1 1.7 0.2 21.1 5.5 0.7 5.6 0.0 0.0 20.2 0.0 1.1 4.1 0.1 0.8 1.4 0.1 0.9 2.1 5.6 0.0 0.0 0.8 0.0 2.4 9.3 16.5 0.0 0.2 12.1 0.1 10.2 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 2.5 2.5 2.3 3.0 3.2 4.9 1.6 0.9 2.0 0.5 2.8 1.4 0.0 0.0 1.1 2.6 0.8 0.4 0.4 0.1 1.2 0.7 1.1 0.8 7.9 0.0 0.1 0.0 6.2 0.3 0.1 26.7 0.0 0.0 1.2 4.0 0.1 0.3 6.1 63.5 11.0 3.1 0.1 0.6 17.9 0.9 0.0 0.1 0.0 0.9 0.1 3.3 12.6 10.9 2.0 0.3 0.0 0.4 0.0 0.2 1.8 1.9 0.0 0.0 0.0 4.5 1.2 1.1 9.2 0.7 2.2 0.9 21.5 0.1 1.7 1.4 0.0 0.7 1.3 10.2 6.1 3.8 1.1 0.0 0.3 0.1 14.7 1.5 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 202.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 202.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" 48.0 48.3 70.0 55.9 73.7 92.0 39.9 61.7 87.0 43.7 63.9 47.0 21.8 42.3 18.8 57.0 44.8 24.5 36.2 72.2 72.0 47.2 62.1 70.9 62.9 76.1 69.2 36.6 43.2 26.9 56.6 25.7 73.6 48.6 27.4 35.2 44.9 20.1 29.9 52.9 63.0 26.8 67.8 160.6 42.8 100.3 72.9 51.1 50.5 13.7 44.9 44.9 46.0 77.8 82.9 63.3 54.8 58.8 37.2 58.8 57.9 97.0 98.0 124.8 124.8 89.1 61.7 59.8 78.6 99.8 63.3 53.8 131.6 83.9 151.5 115.3 72.1 67.6 90.0 101.6 87.9 95.4 70.8 46.3 61.2 111.1 108.9 53.5 73.1 63.4 118.0 31.0 86.0 101.1 116.2 116.1 88.1 43.6 55.4 101.0 64.3 101.2 46.8 45.2 103.3 55.0 52.9 88.3 47.8 60.8 62.7 63.3 75.4 104.1 64.4 87.2 84.8 63.0 83.8 89.8 78.7 98.4 89.1 21.1 9.9 32.9 14.2 11.4 15.4 20.7 16.5 15.8 7.3 15.7 18.1 22.6 202.1 10.7 17.6 9.5 14.7 8.4 70.0 73.7 61.7 87.0 72.2 72.0 76.1 69.2 73.6 67.8 72.9 77.8 9.6 9.6 14.2 27.4 20.2 18.6 11.4 12.6 5.2 20.8 15.0 14.6 8.0 5.7 12.6 23.9 31.3 11.5 30.2 28.5 7.9 14.1 39.2 12.7 21.5 11.6 23.5 10.3 51.2 19.2 17.3 13.3 12.2 32.8 2.5 34.6 9.3 16.7 23.4 21.9 55.4 20.6 10.2 27.9 15.8 44.8 10.8 22.6 7.2 43.1 28.6 8.3 23.7 59.3 90.3 23.4 13.5 8.6 16.5 22.4 13.3 7.1 10.3 28.1 6.6 13.5 12.2 31.6 26.5 18.0 21.3 8.3 27.0 9.5 21.2 15.4 YAP1 YAP65 ENSG00000137693 "Yes1 associated transcriptional regulator" P46937 11 102110447-102233424 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009370, HPA038884, HPA038885, CAB069915, HPA070359" Enhanced Supported "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli, Cell Junctions" "CAB009370: AB_2273277, CAB069915: AB_922796, HPA038884: , HPA038885: AB_2676255, HPA070359: AB_2732154" "unprognostic (9.56e-2)" "unprognostic (6.75e-2)" "unprognostic (2.08e-1)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.28e-1)" "unprognostic (2.66e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (9.26e-2)" "unprognostic (4.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-2)" 57.2 27.8 19.1 25.9 19.1 0.3 42.7 18.6 17.1 62.5 44.3 41.5 27.2 78.1 45.9 74.7 65.6 49.3 48.1 15.9 22.1 39.3 33.5 45.7 13.0 31.8 30.2 93.1 22.3 37.0 9.9 83.1 21.8 59.2 30.1 12.9 40.6 83.7 48.3 44.2 27.4 100.5 27.3 14.7 31.6 15.0 27.0 13.8 85.9 58.2 22.7 60.9 52.6 20.2 56.9 52.1 141.5 69.6 151.1 143.1 118.7 130.4 147.8 124.2 101.5 130.2 134.9 0.0 105.4 171.6 92.1 98.0 71.0 186.4 130.6 16.8 25.5 0.1 67.3 89.5 115.3 0.1 2.5 115.2 119.4 136.6 220.2 138.4 39.4 6.7 0.0 0.1 142.1 27.2 2.6 0.4 66.8 135.9 49.3 0.1 79.7 0.3 90.9 99.5 0.4 4.7 153.6 57.2 43.5 129.1 103.2 0.8 43.4 175.4 68.8 89.6 55.7 0.1 0.2 0.8 51.0 0.2 130.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 19.1 18.6 17.1 15.9 22.1 31.8 30.2 21.8 27.3 27.0 20.2 28.4 35.3 69.4 145.3 1.5 113.7 47.8 43.5 71.2 0.4 48.1 43.8 39.2 62.9 37.2 92.0 0.0 91.4 0.4 16.2 11.7 27.6 6.7 61.8 53.3 28.9 7.3 0.0 1.5 18.3 20.3 49.0 23.9 85.1 0.0 127.2 26.0 45.2 10.6 0.0 1.6 13.1 14.2 1.6 21.5 4.6 37.9 2.2 44.4 60.0 1.0 27.6 0.0 5.0 0.7 25.2 16.3 40.6 0.1 66.0 27.2 26.1 41.6 1.2 39.5 21.6 62.0 2.5 5.3 59.5 123.2 61.6 2.1 15.9 27.8 65.6 YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2038.9" "Cell type enhanced" "Detected in all" "Early spermatids: 8388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: AB_2219278, HPA040304: AB_10795364, HPA057159: AB_2683355" "unprognostic (8.59e-2)" "unprognostic (5.16e-2)" "unprognostic (9.27e-3)" "unprognostic (2.68e-3)" "unprognostic (7.76e-2)" "unprognostic (8.03e-3)" "prognostic unfavorable (9.87e-10)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (2.79e-3)" "unprognostic (7.51e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (3.59e-7)" "unprognostic (3.66e-2)" "unprognostic (2.44e-1)" "unprognostic (1.94e-2)" "unprognostic (3.25e-1)" 532.0 254.5 141.7 422.4 155.4 863.9 401.1 153.3 157.7 331.8 154.4 600.2 364.9 406.2 211.3 365.0 337.0 209.8 789.7 140.6 159.4 318.9 309.9 396.3 407.9 175.1 160.2 311.7 266.7 133.8 122.2 242.2 178.8 307.8 378.1 391.8 270.5 219.5 2038.9 295.0 366.1 338.9 152.7 367.1 405.0 783.5 180.8 353.4 282.0 1133.9 382.2 501.5 332.3 173.5 1552.8 761.5 1020.4 1232.7 991.0 908.1 1200.2 971.5 768.9 1116.6 875.8 1034.6 1253.7 1630.6 1157.5 825.2 495.5 870.2 1162.6 1230.5 1103.9 1087.8 1278.0 1596.4 1491.9 1343.8 786.7 2214.4 1320.7 812.6 1092.3 1094.5 1365.7 630.0 950.3 1271.9 1823.0 720.6 1104.0 837.7 2816.5 2464.6 2902.1 755.0 1006.4 1789.6 1972.5 1938.2 1176.7 933.8 1731.6 1298.5 893.7 1294.0 2038.3 1096.8 443.2 5002.2 862.6 945.4 1748.6 1371.1 2209.3 1213.7 1670.6 2004.8 910.4 1750.3 1049.9 15.3 48.4 69.9 42.9 107.1 52.9 69.4 51.8 43.3 77.4 61.2 44.0 45.9 9.0 35.1 124.2 58.6 69.7 34.1 141.7 155.4 153.3 157.7 140.6 159.4 175.1 160.2 178.8 152.7 180.8 173.5 701.7 173.1 230.9 16.3 818.3 1397.7 1265.9 419.7 747.3 247.8 569.7 564.5 1072.3 441.8 355.5 325.5 150.1 753.9 678.4 620.6 1457.6 1013.6 8388.7 363.5 695.5 755.1 587.8 2244.2 16.2 886.6 1998.9 687.6 461.3 427.0 383.1 489.1 483.3 480.1 1708.7 121.1 27.1 930.2 354.0 1656.0 2342.9 3743.4 751.2 1307.6 905.4 19.7 1171.0 463.8 744.6 23.6 32.7 858.2 975.1 806.1 981.0 1935.1 993.3 1169.8 196.2 602.4 466.8 754.8 1083.7 3245.2 425.5 1113.5 1302.5 481.5 635.6 811.4 1257.7 1697.8 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 129.1;choroid plexus: 65.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: AB_1853855" "unprognostic (5.61e-3)" "unprognostic (8.50e-2)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (7.64e-2)" "unprognostic (3.45e-2)" "unprognostic (3.61e-2)" "unprognostic (3.69e-1)" "unprognostic (8.70e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (6.11e-2)" 7.0 6.2 69.9 5.5 66.9 2.5 8.4 69.6 129.1 6.1 65.6 6.9 5.8 6.9 7.2 5.0 5.0 4.5 7.4 71.7 68.8 7.7 9.2 5.6 5.9 69.3 67.7 6.6 14.8 6.5 5.2 5.9 71.9 6.6 6.2 13.1 7.4 5.6 8.0 7.0 5.8 6.5 66.8 6.9 6.4 4.2 67.3 7.9 10.1 6.0 5.1 5.3 5.1 75.4 8.9 4.4 8.6 7.7 9.8 12.4 4.5 7.5 7.5 7.7 5.0 5.9 6.6 4.7 5.1 8.2 7.4 6.8 9.2 6.6 10.0 7.6 14.3 7.6 9.8 10.7 11.5 10.2 6.2 8.7 12.4 6.9 11.0 10.6 6.6 5.2 10.7 9.6 8.5 5.8 8.0 10.6 7.0 9.6 7.5 5.5 12.7 8.9 8.4 3.8 9.6 9.2 6.4 6.4 11.7 5.5 3.5 8.6 7.4 10.1 4.8 7.1 7.2 14.2 19.1 5.8 15.9 9.7 5.7 14.9 5.4 5.7 4.4 5.1 3.7 4.6 4.4 4.1 4.6 4.0 4.5 4.0 14.9 6.4 5.1 5.4 4.6 4.7 69.9 66.9 69.6 129.1 71.7 68.8 69.3 67.7 71.9 66.8 67.3 75.4 61.4 93.0 69.8 13.1 68.5 51.4 56.9 59.5 50.7 113.8 63.3 28.2 88.0 60.1 58.3 42.3 106.3 68.4 81.3 68.8 33.2 45.3 34.7 39.5 57.9 59.0 57.1 86.9 18.8 39.3 69.9 66.6 28.1 40.1 40.0 56.3 67.8 80.9 48.3 101.0 20.1 70.2 50.8 81.7 60.7 21.0 86.6 58.0 81.8 21.5 85.1 53.1 114.4 22.1 31.8 41.8 66.8 74.9 62.6 78.5 62.7 60.1 62.2 122.2 78.9 71.9 66.2 160.2 59.6 41.1 65.9 192.8 60.7 65.4 46.8 74.7 YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 236.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: AB_2677953, HPA073622: AB_2686618" "prognostic unfavorable (7.83e-5)" "unprognostic (1.13e-3)" "unprognostic (1.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.12e-5)" "prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.64e-2)" "unprognostic (1.20e-3)" "unprognostic (4.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (5.11e-2)" "unprognostic (6.49e-2)" 22.2 20.4 8.3 17.7 9.8 21.0 24.1 9.8 11.0 24.7 16.3 25.8 30.5 20.2 21.2 28.6 20.3 21.4 18.1 9.5 12.5 25.4 31.7 20.3 18.9 9.7 10.3 20.6 32.0 25.7 17.0 30.2 11.5 18.3 26.0 20.6 26.2 19.2 9.3 17.7 27.3 28.5 10.3 15.5 22.7 20.9 10.3 16.1 22.6 14.5 23.9 24.0 14.3 12.0 43.2 28.2 36.0 28.6 84.4 90.5 32.9 143.6 96.9 63.2 101.5 45.3 44.0 23.5 67.3 156.9 72.5 38.7 34.7 70.5 84.8 32.9 30.2 17.4 44.9 46.7 68.0 39.3 27.7 69.1 64.3 56.8 46.3 108.9 61.0 25.6 18.8 38.5 86.4 22.5 19.4 22.2 23.3 27.5 30.7 20.3 53.4 39.3 39.4 37.7 24.4 30.0 49.7 26.4 66.5 36.2 54.9 25.5 236.7 74.0 35.8 72.5 57.2 34.7 61.8 29.9 70.7 36.9 55.2 48.9 34.5 48.7 47.2 47.4 53.1 37.9 47.1 52.4 41.2 36.4 49.0 46.3 26.0 41.0 44.7 45.0 62.8 40.6 8.3 9.8 9.8 11.0 9.5 12.5 9.7 10.3 11.5 10.3 10.3 12.0 43.5 38.5 27.4 8.5 35.6 29.4 24.5 49.4 26.2 40.6 33.4 29.6 21.8 31.5 35.9 20.2 33.3 56.7 40.5 33.0 31.3 43.7 14.9 31.4 49.8 44.1 14.8 20.0 19.7 68.3 77.1 51.9 33.6 31.2 36.8 34.1 30.4 34.7 36.5 33.7 16.9 50.1 22.4 34.0 24.4 7.3 35.4 28.7 30.2 6.5 38.3 54.9 27.8 13.6 16.2 60.5 35.5 33.8 70.0 23.4 56.0 36.1 50.6 53.8 39.5 31.8 45.4 83.9 56.0 33.4 26.0 67.5 42.0 41.1 27.4 24.5 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.6" "Cell type enhanced" "Detected in all" "Erythroid cells: 70.9;Glandular and luminal cells: 118.8;Late spermatids: 103.3;Urothelial cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 86.3;K-562: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 3.0 4.5 3.5 4.3 3.8 58.6 5.4 3.7 5.5 5.2 3.9 3.9 4.2 3.7 2.9 24.6 2.6 2.8 4.4 4.0 3.4 4.7 5.4 8.5 4.7 5.5 3.6 2.9 3.2 1.6 2.7 5.7 4.4 3.0 3.9 7.6 6.6 2.7 4.8 15.6 4.8 2.5 3.6 5.7 8.8 3.8 5.0 9.9 5.3 4.1 7.6 4.6 10.9 9.9 11.8 6.1 9.5 5.7 3.3 4.4 18.5 7.6 5.9 5.7 5.7 11.7 11.9 6.1 3.0 4.7 2.7 12.6 0.1 9.3 6.4 4.9 10.3 86.3 27.6 5.6 3.1 11.5 29.2 3.1 7.1 4.6 17.7 6.7 5.0 12.5 61.1 0.0 5.0 0.1 10.1 6.3 9.1 4.9 13.5 5.1 0.4 4.5 5.7 13.0 5.0 11.0 12.5 14.4 16.7 8.4 5.1 8.1 2.4 4.8 12.6 4.0 10.0 9.5 0.6 9.0 5.7 0.0 3.3 1.0 0.3 0.5 0.2 0.3 0.3 0.0 0.3 0.2 0.3 0.1 0.3 0.4 0.7 0.3 0.2 0.1 0.2 0.2 3.5 3.8 3.7 5.5 4.0 3.4 5.5 3.6 4.4 3.6 5.0 9.9 6.8 41.7 12.2 20.5 3.3 31.6 29.4 8.1 21.1 8.0 6.2 3.8 7.0 2.8 10.0 1.8 4.2 2.7 8.2 39.4 1.9 4.1 35.4 50.5 19.0 6.7 8.9 70.9 8.5 10.5 3.2 5.5 36.2 118.8 8.2 6.1 2.9 8.6 2.8 11.8 6.4 5.0 12.2 10.0 12.5 103.3 1.5 8.3 14.2 6.5 5.2 4.9 6.2 6.0 16.4 24.4 67.8 2.2 4.8 38.2 7.8 7.0 21.6 17.9 6.6 3.6 6.0 10.9 4.6 33.9 40.2 1.8 6.9 9.0 7.5 86.5 YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513694-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.8;Inhibitory neurons: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: AB_10672788, HPA072678: AB_2686548" "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.82e-5)" "unprognostic (4.33e-3)" "unprognostic (1.45e-1)" "unprognostic (6.48e-3)" "unprognostic (1.96e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-2)" "unprognostic (8.56e-3)" "unprognostic (4.61e-2)" "unprognostic (2.03e-1)" "unprognostic (4.15e-2)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" 8.4 9.7 5.2 11.3 5.8 9.9 10.1 8.8 6.6 8.9 7.8 8.7 9.3 9.2 8.6 9.4 8.3 8.0 7.6 6.1 5.1 8.5 12.6 7.4 13.8 5.3 5.8 11.0 8.7 15.5 8.7 6.9 5.3 8.1 10.0 18.3 8.9 7.4 11.5 11.3 10.1 7.9 5.1 11.4 9.2 14.8 4.7 10.2 9.2 10.9 12.9 9.8 8.9 7.1 16.0 14.2 18.1 30.7 9.8 12.9 19.7 12.1 13.4 15.2 23.6 10.0 8.8 29.1 8.5 10.2 19.5 15.3 22.0 27.2 19.8 12.6 19.9 15.8 25.8 13.6 14.5 12.8 13.4 10.6 10.3 9.6 17.4 14.3 21.5 13.0 15.8 13.0 13.6 5.3 17.8 9.1 8.4 4.7 9.2 7.4 15.6 22.7 12.7 20.9 14.4 12.0 16.3 11.7 12.7 11.3 16.6 11.4 18.8 23.2 8.1 12.1 16.7 13.3 18.0 18.0 13.3 14.4 10.1 0.0 2.8 2.9 2.8 1.9 3.3 7.3 3.2 3.0 2.4 5.1 3.4 2.9 1.0 4.3 3.3 3.6 2.6 1.2 5.2 5.8 8.8 6.6 6.1 5.1 5.3 5.8 5.3 5.1 4.7 7.1 27.4 28.9 32.8 61.0 39.6 13.3 21.8 14.7 15.9 59.9 17.6 17.7 17.7 14.3 25.3 12.9 83.4 13.7 34.0 12.3 0.0 17.8 47.5 15.5 24.5 24.0 7.2 16.6 129.8 18.6 8.3 22.4 34.1 17.2 12.6 69.0 20.0 25.7 17.3 52.2 146.3 14.2 20.3 30.0 13.2 44.2 19.9 26.8 12.4 95.5 23.9 21.4 16.5 94.5 97.6 18.0 7.8 14.7 20.0 14.4 16.0 17.8 24.9 88.9 26.3 34.0 26.6 93.8 37.8 19.2 14.3 18.1 33.0 33.4 16.7 18.5 YY1 "DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1" ENSG00000100811 "YY1 transcription factor" P25490 14 100238298-100282788 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001119, CAB009392" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Vesicles" "CAB009392: AB_2218501, HPA001119: AB_1858930" "unprognostic (7.67e-2)" "unprognostic (8.08e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (6.75e-3)" "unprognostic (8.31e-3)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.09e-1)" "unprognostic (4.26e-2)" "unprognostic (7.68e-3)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.30e-1)" "unprognostic (4.30e-1)" 27.2 26.2 20.9 28.9 22.1 56.4 27.0 27.0 24.2 24.6 18.5 30.7 27.9 24.8 34.0 28.9 21.7 22.7 22.8 22.7 20.2 32.9 46.8 24.0 36.0 20.4 20.4 21.6 24.4 32.5 17.4 34.2 20.3 25.2 28.7 20.1 25.1 23.6 36.8 29.0 29.7 24.8 20.1 31.9 26.2 23.8 21.5 52.3 37.2 27.2 38.2 31.9 21.0 26.2 62.0 30.7 64.2 51.5 51.8 65.9 68.1 60.0 55.1 64.7 66.0 38.6 97.7 94.0 82.3 54.5 37.1 64.0 72.6 64.1 88.3 70.8 60.9 86.8 34.6 50.0 48.4 103.8 73.2 38.7 76.4 45.4 61.4 58.6 63.9 67.3 69.9 61.8 63.7 74.5 113.5 61.8 68.7 98.0 56.0 93.9 88.9 50.7 75.8 58.3 68.2 53.3 79.2 57.8 85.1 54.0 86.6 100.1 57.4 39.4 48.3 97.6 53.8 68.3 72.0 126.6 56.4 68.6 52.5 4.8 5.7 11.9 4.3 4.8 5.6 5.3 5.7 5.9 4.9 8.3 5.4 5.4 9.8 9.5 3.8 5.3 7.7 2.7 20.9 22.1 27.0 24.2 22.7 20.2 20.4 20.4 20.3 20.1 21.5 26.2 116.0 54.5 66.8 23.8 102.4 238.0 101.1 49.9 211.7 80.5 129.8 98.2 91.5 92.9 50.0 68.0 81.3 118.6 147.4 122.8 72.4 68.7 10.3 118.7 133.8 115.7 110.1 125.4 28.2 82.0 123.6 106.7 58.1 153.6 71.7 99.4 103.5 119.4 81.3 127.9 26.5 108.8 48.8 111.8 225.8 15.7 94.8 121.6 76.5 30.0 117.8 82.0 114.4 20.6 40.7 80.0 95.5 100.8 125.0 168.9 90.0 104.6 47.6 74.9 92.1 106.5 124.3 86.0 67.0 192.1 243.1 175.5 124.8 124.1 118.7 153.5 Z82206.1 ENSG00000225528 "Novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7" 22 39960397-39964718 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;lymphoid tissue: 4.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 7.9;granulocytes: 3.8;Proximal tubular cells: 3.2;T-cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "K-562: 12.5" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (8.48e-4)" "unprognostic (2.95e-6)" "unprognostic (3.67e-1)" "unprognostic (5.90e-2)" "unprognostic (4.27e-1)" "unprognostic (6.95e-3)" "unprognostic (3.74e-1)" "unprognostic (5.41e-4)" "unprognostic (2.33e-1)" "unprognostic (2.13e-2)" "unprognostic (1.18e-3)" "unprognostic (8.77e-2)" "unprognostic (6.53e-5)" "unprognostic (1.89e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (6.58e-3)" 0.1 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 1.1 0.1 0.1 0.0 4.3 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.4 12.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.1 2.7 2.9 1.3 2.5 2.3 3.5 3.2 1.6 2.0 3.6 4.4 2.4 1.3 1.2 1.7 2.6 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.9 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 ZADH2 MGC45594 ENSG00000180011 "Zinc binding alcohol dehydrogenase domain containing 2" Q8N4Q0 18 75195113-75209139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Golgi apparatus" "HPA021468: AB_1858932, HPA053646: AB_2682216" "unprognostic (3.22e-2)" "unprognostic (1.03e-2)" "unprognostic (7.14e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-1)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (1.49e-1)" "unprognostic (3.62e-3)" "unprognostic (1.42e-1)" "unprognostic (3.05e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.02e-6)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.23e-1)" 17.7 12.9 15.6 11.8 17.8 20.7 22.2 19.2 22.0 18.8 14.0 26.3 19.0 15.5 24.8 20.0 17.9 15.8 34.3 17.0 12.9 24.2 32.5 16.3 19.3 16.8 13.9 23.9 26.6 24.7 21.5 36.6 18.3 17.1 28.7 30.6 23.8 18.2 44.9 22.0 26.0 15.2 16.5 16.1 21.3 7.0 15.5 23.3 27.8 40.7 20.6 16.6 16.9 16.8 21.7 14.1 14.8 30.4 22.6 29.0 16.3 38.5 44.6 14.8 18.5 8.7 30.0 15.2 6.0 38.3 17.4 28.7 18.5 32.6 10.4 94.6 27.1 34.1 32.7 17.0 16.0 58.0 33.2 32.2 31.9 11.9 27.2 27.5 30.9 35.2 18.6 54.0 28.6 25.5 14.6 28.6 3.8 20.9 31.9 31.0 23.7 50.2 28.9 36.2 27.2 22.4 21.4 21.7 24.5 10.4 21.8 28.4 27.7 28.9 22.0 9.2 12.4 8.8 41.2 10.5 19.1 49.5 23.8 1.7 3.4 8.9 3.2 2.9 2.3 2.1 2.6 2.9 2.3 1.5 1.4 2.2 1.7 1.7 3.8 1.7 3.2 1.8 15.6 17.8 19.2 22.0 17.0 12.9 16.8 13.9 18.3 16.5 15.5 16.8 41.5 35.3 17.9 12.4 7.5 9.7 18.7 13.9 9.6 59.0 15.3 10.8 56.3 20.0 12.5 27.6 6.2 8.4 15.9 24.8 19.6 12.3 0.5 8.5 39.0 24.1 23.4 9.9 16.6 21.1 8.1 26.4 12.8 11.1 7.0 42.6 23.6 25.0 16.4 25.2 14.1 25.1 14.2 20.2 19.1 2.1 36.7 18.3 12.4 12.2 23.9 21.3 13.4 20.6 14.9 15.5 21.9 63.2 6.2 18.5 35.2 19.0 8.1 40.9 19.7 25.5 12.3 0.4 4.9 23.7 11.1 6.7 11.0 73.0 27.2 20.9 ZBED1 "ALTE, DREF, hDREF, KIAA0785, TRAMP" ENSG00000214717 "Zinc finger BED-type containing 1" O96006 X 2486414-2500976 "Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 91.0" "Low region specificity" "Detected in all" HPA077591 Approved Approved "Nucleoplasm,Nuclear membrane,Centrosome" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Centrosome" "Nuclear membrane" "HPA077591: AB_2686847" "unprognostic (7.66e-3)" "unprognostic (3.79e-2)" "unprognostic (2.39e-2)" "unprognostic (4.92e-3)" "unprognostic (4.86e-2)" "unprognostic (1.50e-2)" "unprognostic (1.62e-1)" "unprognostic (1.19e-1)" "unprognostic (1.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.53e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (3.95e-2)" "unprognostic (3.27e-1)" 20.4 35.8 16.4 11.8 17.7 7.2 16.8 20.0 16.1 16.9 11.3 16.4 18.9 18.0 5.3 12.2 13.0 12.9 32.5 14.4 17.1 13.9 32.5 12.2 12.5 25.1 21.7 13.1 21.4 11.3 10.4 9.9 22.8 15.4 11.5 8.1 16.8 10.5 70.9 22.3 20.4 9.3 21.3 15.5 14.7 7.8 20.9 11.3 12.1 37.4 9.3 13.1 12.9 16.2 11.6 28.3 20.2 22.4 12.6 13.3 91.0 16.1 17.5 9.3 10.7 36.4 10.0 22.8 18.1 21.5 25.5 5.4 19.5 16.7 6.9 27.0 26.0 17.0 23.4 31.3 16.5 10.6 34.1 19.7 12.8 9.8 7.3 13.8 22.1 15.2 21.9 7.3 18.2 8.2 17.7 8.5 49.9 7.4 16.6 14.0 20.0 10.8 15.6 22.2 24.0 23.6 13.7 36.2 25.6 22.6 10.0 22.3 30.7 19.9 10.5 11.0 17.7 8.7 0.1 37.4 8.1 14.8 11.5 2.2 11.8 10.3 10.6 11.7 9.3 8.4 6.1 5.9 13.3 11.2 5.7 4.9 12.5 5.5 9.8 9.7 6.4 11.7 16.4 17.7 20.0 16.1 14.4 17.1 25.1 21.7 22.8 21.3 20.9 16.2 12.9 12.8 11.7 0.0 20.7 15.2 17.6 14.1 29.6 55.5 12.9 12.4 27.8 40.0 9.2 25.8 14.6 15.9 18.7 23.3 11.7 22.8 0.4 23.0 18.2 17.5 15.5 7.6 0.0 23.4 18.0 22.6 8.2 28.5 14.7 37.1 18.5 37.3 18.0 10.1 0.0 19.4 10.2 22.2 24.9 1.3 19.9 19.5 8.8 0.0 23.0 20.5 34.0 0.0 0.0 22.7 17.3 23.0 8.8 19.7 25.5 18.1 15.8 23.5 6.6 23.7 19.2 0.7 2.6 15.8 11.2 38.0 14.4 29.5 23.2 12.9 ZBED2 MGC10796 ENSG00000177494 "Zinc finger BED-type containing 2" Q9BTP6 3 111592900-111595346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 47.6;thyroid gland: 71.0" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 1: 44.8" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 64.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "CAPAN-2: 54.8;EFO-21: 37.4;HaCaT: 53.1;HBEC3-KT: 119.3;RPTEC TERT1: 77.6" "Not detected" "Not detected" HPA029786 Approved "Nuclear bodies,Mitochondria,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Mitochondria, Cytosol" "Nuclear bodies" "HPA029786: AB_10601028" "unprognostic (7.31e-3)" "unprognostic (1.67e-1)" "unprognostic (1.98e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-3)" "unprognostic (3.49e-1)" "unprognostic (7.61e-2)" "unprognostic (1.47e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.83e-4)" "unprognostic (2.59e-1)" "unprognostic (1.47e-6)" "unprognostic (3.81e-2)" "unprognostic (4.34e-1)" "unprognostic (4.69e-2)" "unprognostic (3.29e-2)" 0.2 0.0 0.0 1.7 0.4 0.3 0.2 0.0 0.1 5.4 0.0 0.1 0.1 0.1 0.2 12.8 20.0 0.3 0.1 0.0 0.0 0.2 0.0 10.4 6.9 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.0 2.8 0.4 0.0 2.2 0.5 0.0 0.0 0.3 0.5 0.0 0.0 47.6 71.0 0.0 12.9 0.4 9.9 0.0 15.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 54.8 0.5 37.4 0.0 0.0 53.1 0.0 119.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 10.8 0.0 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.3 1.2 0.2 0.1 0.0 2.1 0.6 0.8 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 1.1 0.0 0.6 4.5 0.3 3.1 4.6 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.6 3.8 0.0 4.5 0.0 0.1 0.2 ZBED5 Buster1 ENSG00000236287 "Zinc finger BED-type containing 5" Q49AG3 11 10812074-10858796 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048472, HPA050994" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center" "HPA048472: AB_2680408, HPA050994: AB_2681300" "unprognostic (7.74e-2)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (4.72e-2)" "unprognostic (3.40e-1)" "unprognostic (9.05e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (5.69e-2)" "unprognostic (4.61e-2)" "unprognostic (2.23e-2)" "unprognostic (2.25e-2)" "unprognostic (3.27e-2)" "unprognostic (8.77e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic favorable (3.87e-4)" 26.4 22.0 16.9 36.6 22.5 34.1 32.7 35.3 20.0 39.4 23.3 33.1 25.6 45.6 35.7 26.4 38.5 25.8 32.5 16.8 18.0 33.1 15.7 31.5 57.1 20.1 18.5 45.1 28.8 35.0 30.5 27.9 21.1 36.3 29.9 50.8 29.6 21.9 33.3 51.4 36.5 28.9 19.5 42.9 28.5 21.3 18.7 49.7 40.1 29.1 45.4 30.7 31.7 32.7 46.8 36.7 63.1 41.2 33.8 52.0 32.7 37.4 38.2 24.8 24.5 27.0 99.6 50.7 27.5 28.0 34.5 56.8 39.8 39.3 33.1 49.8 35.5 13.4 89.3 15.6 27.5 42.3 17.1 36.0 55.3 18.8 41.0 44.3 31.0 25.3 35.0 56.0 36.0 23.6 41.9 46.2 34.1 33.3 47.8 62.8 34.3 27.4 29.2 64.6 30.9 54.4 38.4 49.1 30.6 35.3 46.8 23.1 31.1 53.2 38.4 35.9 26.6 27.9 36.8 39.8 46.0 29.5 41.2 1.1 8.7 8.0 11.0 9.6 14.3 20.6 13.1 14.1 12.2 21.2 17.0 17.2 7.3 17.8 11.6 15.8 12.3 8.5 16.9 22.5 35.3 20.0 16.8 18.0 20.1 18.5 21.1 19.5 18.7 32.7 17.1 57.7 33.0 32.0 44.6 34.7 46.1 25.0 34.7 32.8 15.9 11.8 38.8 20.0 39.4 22.0 29.2 17.1 13.6 12.3 23.5 22.2 6.9 13.9 29.4 22.7 27.6 8.8 18.1 16.2 8.5 27.3 15.3 14.0 8.8 25.8 20.7 6.2 12.1 28.6 22.3 15.6 26.4 15.7 19.8 7.9 27.4 19.3 16.0 16.9 18.1 21.6 14.4 25.6 40.9 18.3 13.1 27.4 26.6 25.3 12.5 14.5 42.7 35.8 19.7 41.2 25.2 43.4 22.2 25.9 35.7 12.4 22.6 18.7 16.7 28.5 ZBED9 "Buster4, FLJ31087, KIAA1925, SCAND3, ZFP38-L, ZNF305P2, ZNF452" ENSG00000232040 "Zinc finger BED-type containing 9" Q6R2W3 6 28570535-28616212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.7" "Group enriched" "Detected in many" 4 "Early spermatids: 27.2;Spermatocytes: 24.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.7;hTCEpi: 4.4;K-562: 8.3;U-266/84: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007246 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoli "Nucleoplasm, Golgi apparatus" "HPA007246: AB_1080727" "unprognostic (1.01e-1)" "unprognostic (5.16e-5)" "unprognostic (1.88e-1)" "unprognostic (1.27e-4)" "unprognostic (3.96e-2)" "unprognostic (9.46e-3)" "unprognostic (3.40e-1)" "unprognostic (2.73e-2)" "unprognostic (4.24e-2)" "unprognostic (2.34e-3)" "unprognostic (8.21e-3)" "unprognostic (4.31e-1)" "unprognostic (2.42e-2)" "unprognostic (1.14e-2)" "unprognostic (7.66e-3)" "unprognostic (3.92e-2)" "unprognostic (1.59e-1)" 0.1 0.5 0.8 0.1 0.6 0.1 0.9 1.6 0.8 0.8 0.1 0.4 0.2 0.6 3.1 0.2 1.2 0.2 0.3 0.6 0.6 0.8 1.2 0.5 0.1 0.2 0.3 1.6 0.8 0.9 0.7 0.6 0.3 1.4 0.5 1.5 0.7 1.9 0.0 0.2 0.2 0.3 0.1 0.0 0.3 8.7 0.4 0.4 1.7 0.0 0.1 0.2 0.3 0.4 1.1 1.2 1.2 0.0 0.0 0.0 1.3 0.2 0.0 0.2 0.7 0.0 0.7 0.0 4.7 0.1 2.4 0.6 0.0 1.3 0.2 0.0 3.0 0.2 0.8 1.1 0.7 0.0 0.0 0.6 4.4 0.1 2.1 0.7 0.0 0.0 8.3 0.0 0.0 0.9 0.0 0.0 1.1 0.0 0.6 0.4 0.5 0.0 1.3 1.3 1.2 2.8 0.0 1.2 0.0 1.6 0.0 0.3 0.0 0.0 1.3 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.6 1.6 0.8 0.6 0.6 0.2 0.3 0.3 0.1 0.4 0.4 0.0 0.0 3.2 0.3 0.2 0.0 0.9 0.0 2.2 1.6 1.5 0.8 1.9 2.8 0.6 0.0 2.1 2.8 0.0 1.0 1.9 1.7 27.2 1.1 0.3 0.3 1.2 0.0 5.2 1.3 1.5 0.3 0.0 1.1 0.0 1.7 0.0 1.9 0.4 0.0 5.7 1.4 0.0 0.0 0.0 5.4 2.5 0.1 0.0 0.0 0.1 1.1 0.0 1.0 0.2 0.4 0.8 0.0 0.0 0.9 0.5 0.6 0.7 1.5 0.0 0.2 0.2 24.9 3.5 1.3 0.0 1.0 0.0 0.2 1.2 0.6 ZBTB14 "ZFP161, ZNF478" ENSG00000198081 "Zinc finger and BTB domain containing 14" O43829 18 5289019-5297053 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050758, HPA070819" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nucleoli, Cytosol" "HPA050758: AB_2681226, HPA070819: AB_2686316" "unprognostic (5.28e-2)" "unprognostic (4.37e-2)" "unprognostic (4.25e-2)" "unprognostic (2.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-2)" "unprognostic (2.95e-2)" "unprognostic (8.64e-2)" "unprognostic (1.19e-3)" "unprognostic (4.72e-3)" "unprognostic (3.25e-2)" "unprognostic (1.49e-1)" "unprognostic (3.70e-2)" "unprognostic (2.03e-1)" "unprognostic (2.53e-1)" "unprognostic (3.73e-1)" "unprognostic (2.90e-2)" 10.3 8.6 9.3 14.7 10.5 9.6 12.5 11.4 12.2 9.6 7.4 10.4 8.7 9.9 16.4 12.4 10.6 12.0 8.6 8.7 9.6 11.2 13.4 11.1 24.7 9.5 10.3 15.6 14.4 12.0 4.8 9.1 9.6 9.8 10.0 7.3 12.2 12.1 8.5 14.0 9.3 8.7 10.2 16.2 11.9 5.9 9.5 21.8 15.5 8.4 21.8 9.6 5.2 11.4 9.0 11.8 15.1 11.2 11.0 14.5 10.0 8.8 13.0 12.0 10.5 11.3 11.5 31.2 7.6 10.7 13.9 8.2 11.2 13.2 12.2 6.0 6.0 12.4 11.1 10.5 7.8 15.8 14.4 11.6 10.9 8.5 7.9 13.0 19.2 22.3 8.1 10.1 12.4 9.9 23.8 10.5 13.4 11.1 6.0 14.0 9.7 9.2 10.0 10.8 13.3 13.0 13.4 8.8 14.3 15.0 10.5 17.9 10.7 15.6 12.8 12.2 13.3 6.4 6.9 19.9 16.4 13.3 14.0 9.8 5.5 14.1 8.7 7.8 8.6 7.5 11.0 10.0 8.2 10.4 11.6 11.1 1.2 7.6 7.5 6.1 7.6 7.3 9.3 10.5 11.4 12.2 8.7 9.6 9.5 10.3 9.6 10.2 9.5 11.4 8.8 6.4 6.7 5.9 8.5 2.4 1.6 2.9 5.2 7.4 5.6 4.3 3.6 1.5 2.2 5.5 0.0 5.3 6.3 5.5 5.9 4.9 0.8 4.3 5.5 7.4 1.2 9.1 2.9 3.3 5.5 4.6 0.5 3.7 15.9 6.0 11.7 6.9 7.1 5.0 3.1 5.1 8.2 7.5 4.5 2.8 5.9 6.3 1.8 1.0 7.8 10.8 6.2 2.5 6.6 3.5 4.0 5.7 2.2 2.4 5.7 5.5 2.5 5.9 0.0 6.0 5.7 1.0 9.3 4.2 3.0 2.2 8.8 5.1 5.2 1.5 ZBTB24 "BIF1, KIAA0441, PATZ2, ZNF450" ENSG00000112365 "Zinc finger and BTB domain containing 24" O43167 6 109462594-109483219 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017872, HPA049003" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Centrosome" Yes No "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Cytokinetic bridge, Centrosome" "HPA017872: AB_2669673, HPA049003: AB_2680596" "unprognostic (8.15e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" "unprognostic (4.80e-2)" "unprognostic (1.98e-2)" "prognostic unfavorable (3.15e-4)" "unprognostic (4.53e-2)" "unprognostic (5.09e-2)" "unprognostic (3.31e-2)" "unprognostic (1.22e-3)" "unprognostic (1.37e-1)" "unprognostic (1.75e-3)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.60e-1)" "unprognostic (6.77e-2)" 3.1 2.2 1.5 5.4 2.4 8.9 4.6 2.4 2.4 4.0 1.0 3.5 3.6 3.1 3.2 3.0 2.9 2.5 2.2 1.6 1.9 3.9 2.6 3.9 8.7 1.5 1.2 3.4 3.5 7.4 1.8 3.2 1.6 3.5 3.8 10.1 4.4 3.3 3.2 4.7 3.7 2.8 1.3 5.5 4.1 4.3 1.6 6.9 4.9 2.9 7.3 3.5 2.7 2.9 4.7 4.8 4.3 10.8 6.8 6.9 7.0 5.3 7.3 6.5 7.4 6.7 3.6 20.0 6.7 6.7 7.8 6.0 10.9 8.3 9.8 12.4 10.7 16.2 6.5 5.1 5.0 13.3 8.0 7.0 6.7 6.6 11.4 4.6 5.5 9.3 13.8 11.0 6.8 8.0 19.2 9.0 10.7 4.7 5.3 11.9 6.1 8.3 8.0 8.0 7.3 6.4 6.8 7.1 16.9 5.9 5.0 14.5 5.4 5.3 5.3 4.4 11.5 5.3 4.4 20.2 7.0 10.4 9.0 0.1 0.6 0.9 0.7 0.6 0.4 3.4 1.5 0.9 0.7 2.8 1.9 1.1 0.4 1.3 0.8 1.1 2.9 0.5 1.5 2.4 2.4 2.4 1.6 1.9 1.5 1.2 1.6 1.3 1.6 2.9 8.4 12.8 9.1 2.6 32.8 10.1 11.2 5.3 7.4 21.7 8.6 7.4 3.8 7.2 5.2 3.7 31.3 8.5 16.8 4.5 3.9 6.6 1.4 7.3 14.3 6.6 9.6 12.0 3.3 9.1 9.9 8.6 12.8 10.7 9.5 14.1 3.6 7.3 7.7 10.1 2.8 11.0 6.1 12.5 12.1 1.8 7.2 10.3 8.8 5.6 20.5 10.0 14.4 1.0 5.4 6.4 5.1 6.4 16.8 8.2 7.4 6.4 6.0 65.2 0.0 13.2 7.4 6.2 27.8 9.3 9.7 7.8 17.8 15.0 8.5 7.3 ZBTB33 "kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348" ENSG00000177485 "Zinc finger and BTB domain containing 33" Q86T24 X 120250752-120258398 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000755, CAB001980, HPA005732" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB001980: , HPA000755: AB_1079167, HPA005732: AB_1079166" "unprognostic (9.14e-3)" "unprognostic (1.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.47e-2)" "unprognostic (6.13e-2)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.51e-2)" "unprognostic (5.08e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (6.44e-2)" "unprognostic (2.59e-2)" 6.4 7.0 6.4 8.5 7.0 19.5 15.4 7.1 9.0 6.8 4.7 6.8 7.7 6.2 9.4 9.9 8.2 7.3 4.9 6.4 9.2 6.4 19.0 8.7 13.2 7.3 8.7 9.7 8.4 13.7 4.8 8.8 8.5 7.4 6.5 5.7 10.4 6.0 5.4 18.8 6.4 4.8 8.4 11.5 8.6 5.7 9.3 16.2 10.2 7.7 12.8 8.0 4.8 9.7 13.6 12.9 19.6 18.1 15.9 17.8 23.4 10.3 13.5 11.7 14.5 9.0 11.7 19.5 18.8 10.4 15.7 20.7 31.9 15.7 15.3 22.0 21.6 20.3 20.3 12.7 11.6 21.2 22.7 12.7 19.9 11.2 17.6 17.1 20.9 18.7 13.5 23.2 14.6 15.6 19.2 14.1 24.3 20.9 15.3 21.9 14.9 32.0 12.5 22.2 35.6 15.2 20.9 21.3 25.3 14.9 11.5 29.6 19.6 9.5 6.9 14.3 18.5 12.7 13.1 24.7 12.6 29.4 11.9 11.5 4.2 5.6 2.9 6.4 5.0 2.4 3.8 3.9 6.2 2.2 4.6 3.4 0.9 4.0 4.2 6.7 3.5 3.6 6.4 7.0 7.1 9.0 6.4 9.2 7.3 8.7 8.5 8.4 9.3 9.7 15.7 16.0 7.0 3.9 7.9 12.7 7.8 5.1 12.5 4.5 11.5 13.1 5.2 8.6 11.9 1.8 0.0 7.7 21.7 5.3 1.9 5.5 0.1 12.9 8.7 8.5 8.4 10.3 3.4 6.7 8.7 7.9 7.1 10.3 0.0 16.0 7.9 16.6 7.6 3.3 4.6 7.0 6.1 12.8 10.3 0.4 4.4 8.2 3.6 3.7 14.6 7.0 14.4 5.0 4.6 6.9 5.7 2.6 5.4 9.5 6.8 4.0 15.3 1.6 6.6 6.9 4.1 5.0 10.0 12.7 13.1 9.3 8.7 11.2 6.0 11.9 ZBTB37 "MGC2629, ZNF908" ENSG00000185278 "Zinc finger and BTB domain containing 37" Q5TC79 1 173868082-173903549 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 12.7" "Cell type enhanced" "Detected in many" "Early spermatids: 60.2;Late spermatids: 67.0;Rod photoreceptor cells: 60.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023438 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA023438: AB_1858954" "unprognostic (1.18e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-2)" "unprognostic (2.51e-1)" "unprognostic (5.46e-2)" "unprognostic (2.66e-4)" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (9.86e-2)" "unprognostic (2.41e-1)" "unprognostic (3.72e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (4.03e-3)" "unprognostic (1.96e-2)" 3.0 1.6 4.6 2.6 7.5 5.7 2.6 6.3 4.6 2.8 2.1 1.9 1.8 2.1 2.3 1.4 2.1 1.6 2.0 4.4 4.6 2.2 2.1 2.7 3.8 8.6 6.3 3.3 2.0 1.8 2.6 2.1 9.2 2.3 1.6 10.8 2.0 1.4 1.8 3.2 2.3 1.8 4.4 3.8 2.3 9.3 6.4 3.2 2.7 2.2 3.0 2.0 2.3 12.7 1.7 2.5 3.8 1.6 2.3 1.8 4.2 1.5 1.1 2.7 1.9 3.2 2.1 4.6 3.1 2.4 1.4 2.1 3.2 1.7 2.2 2.6 2.0 6.4 3.0 1.6 1.3 3.8 3.9 1.7 1.1 4.0 2.6 1.6 1.4 3.2 5.7 3.0 2.8 1.2 2.6 0.9 3.6 1.3 0.6 1.7 3.3 1.5 1.5 4.2 2.8 3.5 2.1 2.9 2.8 4.0 4.2 3.9 2.5 3.5 3.7 1.7 2.4 5.3 4.2 7.3 2.3 2.1 2.1 0.1 0.4 1.4 1.1 0.4 0.4 0.2 0.5 0.7 0.2 0.6 0.2 0.6 2.3 0.9 0.4 0.9 0.4 0.3 4.6 7.5 6.3 4.6 4.4 4.6 8.6 6.3 9.2 4.4 6.4 12.7 8.5 6.4 6.3 2.0 9.7 2.9 3.7 3.6 4.0 27.2 5.7 2.8 9.2 12.8 4.2 11.0 33.3 8.3 11.9 4.6 7.9 3.6 60.2 9.1 8.8 6.8 3.5 5.7 1.6 3.8 3.9 7.4 5.1 7.6 2.5 16.9 11.0 4.7 5.0 18.5 2.1 3.9 0.0 15.4 5.5 67.0 8.7 10.0 10.6 2.8 10.6 10.3 18.6 3.5 5.3 2.8 2.7 13.2 5.7 4.3 4.7 5.4 10.6 60.1 6.6 9.5 10.8 23.2 13.2 3.2 5.8 9.2 9.3 11.6 3.6 3.4 ZBTB4 "KAISO-L1, KIAA1538, ZNF903" ENSG00000174282 "Zinc finger and BTB domain containing 4" Q9P1Z0 17 7459366-7484263 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008980, HPA064763" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB008980: , HPA064763: AB_2685347" "unprognostic (2.23e-1)" "unprognostic (3.95e-1)" "unprognostic (7.17e-2)" "unprognostic (2.92e-2)" "unprognostic (5.32e-2)" "unprognostic (7.62e-3)" "unprognostic (2.43e-1)" "unprognostic (1.67e-2)" "unprognostic (1.28e-1)" "unprognostic (1.63e-3)" "prognostic favorable (2.53e-4)" "unprognostic (1.73e-1)" "prognostic favorable (1.65e-9)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.88e-1)" "unprognostic (6.04e-3)" 34.8 36.1 22.1 7.4 20.6 3.0 31.4 19.9 23.1 41.9 11.7 47.2 6.3 40.3 16.2 26.4 40.5 9.6 38.8 21.2 21.0 24.1 7.8 30.0 8.3 27.1 21.7 48.4 23.1 36.1 28.6 10.8 27.0 33.1 6.6 23.1 28.0 21.4 32.4 27.2 23.0 16.4 19.7 22.1 27.3 15.9 23.3 9.5 43.9 14.8 9.0 42.3 33.9 21.5 10.7 14.4 3.6 6.9 37.1 19.1 6.5 14.7 21.0 13.0 12.9 4.8 5.1 1.1 11.4 28.0 9.5 16.7 3.6 20.6 9.5 17.0 6.2 5.3 12.3 3.4 10.4 1.0 12.2 13.4 21.1 12.5 15.9 30.6 11.5 4.0 1.8 3.4 14.5 7.1 3.7 2.2 1.5 4.3 6.8 6.8 6.2 1.6 15.9 8.9 2.1 5.3 6.5 4.6 6.9 6.3 8.6 2.4 16.1 14.6 5.7 13.9 12.3 6.1 4.5 0.7 15.7 3.3 7.7 0.4 0.3 0.5 1.0 0.5 1.0 0.5 0.8 0.8 0.2 0.5 1.0 1.0 0.2 0.6 1.7 0.4 0.4 0.6 22.1 20.6 19.9 23.1 21.2 21.0 27.1 21.7 27.0 19.7 23.3 21.5 27.4 51.3 53.1 33.6 14.6 30.7 16.3 18.4 18.8 86.6 23.6 20.6 92.6 20.0 24.8 20.2 68.8 10.3 24.5 4.6 3.9 14.4 40.8 21.1 25.2 26.1 17.4 9.5 36.9 14.4 2.2 24.8 7.1 26.0 13.9 25.7 23.9 8.1 13.5 74.0 37.3 10.1 14.2 30.0 34.6 57.0 51.9 18.6 17.8 15.9 12.0 27.0 24.7 21.6 26.7 19.0 5.3 70.0 9.5 16.2 8.2 11.2 32.2 39.9 32.9 37.8 27.4 7.3 4.3 17.3 23.4 5.2 21.1 16.3 9.0 14.7 ZBTB41 "DKFZp686C06120, FLJ36199, FRBZ1, ZNF924" ENSG00000177888 "Zinc finger and BTB domain containing 41" Q5SVQ8 1 197153682-197201293 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034841, HPA034842" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Cytosol" Nucleoplasm "HPA034841: AB_2674355, HPA034842: AB_10669995" "unprognostic (2.36e-1)" "unprognostic (5.58e-3)" "unprognostic (8.01e-3)" "unprognostic (6.07e-2)" "unprognostic (4.14e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.43e-1)" "unprognostic (1.81e-2)" "unprognostic (2.81e-1)" "unprognostic (7.51e-3)" "unprognostic (2.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (2.98e-2)" "unprognostic (1.58e-1)" 3.5 4.7 5.0 3.0 4.7 1.3 7.0 6.6 5.8 5.2 2.2 3.2 3.2 4.2 4.7 3.4 3.7 4.3 3.2 4.6 5.8 5.3 4.4 3.4 3.9 5.5 6.1 6.8 4.0 4.8 3.9 3.3 5.6 4.2 3.5 7.0 3.9 3.4 3.6 3.5 2.9 3.2 6.0 4.4 4.3 3.8 5.8 5.2 7.5 4.7 3.3 3.9 2.4 6.9 8.1 4.6 5.8 4.7 9.0 13.6 4.6 4.8 7.8 4.9 4.6 2.9 6.7 3.0 6.8 10.9 3.0 6.5 4.1 4.1 7.7 2.7 2.4 2.4 6.0 2.6 8.0 4.8 2.3 5.6 10.6 5.0 8.6 10.0 3.4 3.4 5.7 3.5 12.8 3.9 3.6 2.7 2.3 5.6 1.6 2.5 8.1 5.4 6.0 4.5 8.3 7.4 8.6 14.9 9.3 4.2 11.4 3.6 5.6 9.7 5.6 7.8 6.3 4.0 2.2 3.2 4.6 1.7 13.8 0.3 0.1 0.1 0.2 0.1 0.4 0.4 0.3 0.3 0.3 0.3 0.4 0.4 0.0 0.4 0.1 0.1 0.2 0.1 5.0 4.7 6.6 5.8 4.6 5.8 5.5 6.1 5.6 6.0 5.8 6.9 11.6 19.2 8.9 21.2 9.4 7.5 6.9 5.8 11.4 13.6 17.5 10.7 14.7 10.0 10.0 16.5 2.1 4.3 10.6 4.2 1.9 6.3 3.2 14.5 18.0 8.2 13.1 1.7 32.1 5.7 4.0 13.3 7.7 11.3 1.3 18.5 6.8 9.2 4.4 25.2 27.9 7.3 2.0 7.3 5.2 4.6 15.5 8.1 12.4 13.1 9.3 28.5 11.3 19.6 41.0 6.8 2.9 12.0 6.3 9.4 4.3 10.4 12.8 9.1 6.6 13.3 12.7 7.0 4.9 10.8 10.1 3.4 7.7 16.0 7.0 6.0 ZBTB49 "FLJ38559, ZNF509" ENSG00000168826 "Zinc finger and BTB domain containing 49" Q6ZSB9 4 4290251-4321786 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024450 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Microtubules, Cytosol" "HPA024450: AB_1859311" "unprognostic (4.30e-2)" "unprognostic (5.30e-3)" "unprognostic (1.30e-1)" "unprognostic (2.49e-2)" "unprognostic (2.54e-1)" "prognostic favorable (5.24e-4)" "unprognostic (3.56e-2)" "unprognostic (2.77e-2)" "unprognostic (4.74e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.76e-4)" "unprognostic (5.54e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "prognostic favorable (2.88e-5)" 2.3 1.8 0.8 2.2 0.7 5.1 2.4 1.0 1.6 2.4 1.1 2.1 1.6 2.2 2.4 1.8 1.9 1.9 2.3 0.8 0.8 1.8 1.9 2.4 3.0 0.9 0.7 3.7 2.9 2.1 3.1 2.0 1.2 2.8 1.6 3.4 2.2 2.2 2.9 2.2 1.9 2.3 0.4 3.5 1.7 4.0 1.0 2.0 2.9 2.1 3.0 2.4 2.1 2.3 1.4 2.2 2.7 4.6 3.6 3.7 3.2 1.6 3.2 3.6 2.8 1.9 2.6 4.9 1.7 1.9 4.4 2.3 4.8 2.8 3.7 1.6 1.9 5.7 1.5 2.8 2.8 3.5 2.0 2.4 2.3 3.3 2.1 2.0 3.6 5.2 3.0 2.6 3.4 2.2 6.9 6.7 4.7 2.0 3.0 4.1 3.6 3.1 1.4 2.4 3.3 3.2 3.7 1.4 3.7 3.6 2.0 3.3 3.6 3.2 1.4 2.0 3.7 3.1 3.3 4.3 2.3 2.9 3.2 2.9 2.0 9.8 4.6 2.1 3.8 1.6 2.6 4.5 1.5 2.4 2.9 3.4 4.6 2.8 1.8 0.3 2.6 1.5 0.8 0.7 1.0 1.6 0.8 0.8 0.9 0.7 1.2 0.4 1.0 2.3 3.1 0.0 1.1 3.9 5.3 2.5 1.9 1.8 2.2 2.9 2.2 3.4 1.9 1.5 2.1 1.8 4.2 2.0 5.8 0.8 0.0 1.9 2.7 1.2 2.7 3.1 1.2 3.6 11.5 2.6 1.5 3.1 2.0 1.3 1.3 5.4 3.9 2.2 1.8 1.7 12.5 1.8 2.0 3.1 2.4 0.7 1.5 2.7 3.6 4.7 4.5 1.7 9.2 11.6 10.0 1.1 2.9 2.2 6.6 2.1 1.8 0.9 1.3 8.2 0.0 2.2 2.1 9.7 5.5 1.7 2.6 1.5 6.3 4.6 1.6 1.2 ZBTB5 KIAA0354 ENSG00000168795 "Zinc finger and BTB domain containing 5" O15062 9 37438102-37465450 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021521 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA021521: AB_2670736" "unprognostic (2.36e-2)" "unprognostic (2.78e-2)" "unprognostic (5.22e-2)" "unprognostic (6.35e-2)" "unprognostic (1.55e-2)" "unprognostic (2.08e-2)" "unprognostic (4.96e-3)" "unprognostic (5.81e-2)" "unprognostic (3.95e-2)" "unprognostic (1.43e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" "unprognostic (1.27e-3)" "unprognostic (5.73e-3)" "unprognostic (2.30e-1)" "unprognostic (2.77e-3)" "unprognostic (1.80e-1)" 4.9 6.2 4.9 5.6 5.8 13.6 7.4 5.9 5.0 6.3 5.0 6.1 6.3 6.3 7.7 17.8 5.9 5.4 5.5 4.7 5.0 7.4 12.9 7.9 9.0 5.7 5.3 8.4 8.4 7.6 4.7 6.2 5.5 7.2 5.8 9.2 7.8 6.7 5.2 11.9 7.2 5.3 5.0 7.2 7.2 8.8 5.2 9.5 10.3 7.2 12.1 5.6 9.3 7.8 9.3 10.5 26.6 16.6 6.7 4.7 11.4 7.5 5.8 9.0 7.4 7.8 6.7 18.8 7.9 5.6 6.6 11.1 17.5 6.2 6.9 13.9 9.1 6.9 28.7 9.1 6.5 8.6 5.8 4.5 15.5 4.5 9.5 10.2 10.2 14.8 16.6 15.6 6.8 5.9 18.2 6.3 6.8 10.0 5.3 16.3 12.8 7.2 8.7 8.2 12.2 21.9 7.3 11.7 5.8 13.3 18.7 8.3 7.0 6.3 17.3 3.7 7.2 8.3 9.8 16.3 5.8 7.3 6.8 0.1 0.4 0.0 0.6 0.2 0.7 0.9 0.5 0.5 0.8 0.7 0.8 0.9 0.0 0.3 0.0 0.2 0.5 0.3 4.9 5.8 5.9 5.0 4.7 5.0 5.7 5.3 5.5 5.0 5.2 7.8 4.0 16.0 6.5 12.7 5.1 14.3 8.8 5.0 11.4 2.0 8.4 6.6 3.2 7.2 9.3 1.8 6.2 3.9 3.7 6.5 0.0 4.0 2.2 7.3 4.2 5.6 8.4 2.1 8.9 3.2 2.2 4.2 5.1 7.3 1.3 6.6 3.6 8.6 2.4 13.5 9.1 5.2 4.1 1.9 4.8 5.3 4.1 3.4 3.6 10.3 3.7 3.3 1.0 13.6 15.5 4.1 3.7 3.8 4.2 12.6 3.1 3.5 6.0 5.1 0.0 5.4 4.0 7.5 7.9 17.9 18.2 5.7 2.7 4.4 5.1 8.2 ZBTB9 "MGC23166, ZNF919" ENSG00000213588 "Zinc finger and BTB domain containing 9" Q96C00 6 33453970-33457544 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.5;Ionocytes: 6.1;Respiratory ciliated cells: 4.3;Suprabasal keratinocytes: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 11.6;BEWO: 11.3;GAMG: 16.5;HMC-1: 14.2;U-698: 12.0" "Low region specificity" "Detected in all" "HPA036767, HPA058171" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear membrane, Cytosol" "HPA036767: AB_10696787, HPA058171: " "unprognostic (1.79e-2)" "unprognostic (1.46e-1)" "unprognostic (6.86e-2)" "unprognostic (2.89e-1)" "unprognostic (2.18e-1)" "unprognostic (9.16e-2)" "unprognostic (1.85e-4)" "unprognostic (4.20e-1)" "unprognostic (2.73e-1)" "unprognostic (2.13e-1)" "unprognostic (1.70e-2)" "unprognostic (4.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-1)" "unprognostic (2.95e-1)" 2.8 3.9 0.9 1.5 1.0 1.7 2.3 0.8 1.6 2.5 8.6 2.4 2.3 2.6 1.7 3.8 2.5 0.6 3.0 1.9 0.7 4.4 3.2 2.4 1.9 1.2 0.9 3.0 2.9 0.6 10.0 0.5 0.6 2.4 1.4 1.9 2.9 0.1 1.8 3.8 2.7 0.8 0.2 3.5 2.7 7.4 0.4 0.2 2.2 1.0 3.3 2.5 2.2 0.9 1.0 0.3 11.6 2.9 2.1 0.1 11.3 0.6 0.2 0.2 0.1 3.0 0.8 2.7 1.8 0.3 16.5 1.2 4.8 2.4 1.3 3.1 2.0 9.0 2.3 0.0 0.0 2.3 14.2 0.5 0.9 3.3 2.6 0.6 0.1 1.5 3.2 1.8 2.6 1.6 0.6 0.9 4.3 0.5 0.7 5.6 3.0 2.7 2.2 2.3 1.8 1.1 3.3 0.3 1.1 1.1 1.6 0.4 1.9 0.9 1.3 1.3 1.2 0.7 3.5 12.0 0.9 2.9 0.3 5.2 1.1 0.4 2.8 0.8 1.2 0.4 1.2 2.6 1.5 0.8 2.5 1.9 0.8 1.3 1.7 0.3 2.2 0.6 0.9 1.0 0.8 1.6 1.9 0.7 1.2 0.9 0.6 0.2 0.4 0.9 0.1 0.0 0.0 1.3 2.1 4.5 0.0 1.9 1.8 0.0 0.2 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.3 0.4 0.1 0.6 1.8 1.3 1.2 1.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.7 6.1 0.0 1.2 1.1 0.0 0.2 1.8 1.0 0.0 0.0 0.0 0.0 0.6 1.0 0.1 0.0 0.6 0.0 0.2 0.1 4.3 0.0 0.0 0.0 0.7 0.1 0.1 0.8 3.7 0.0 0.7 0.1 1.0 0.0 ZC3H12B "CXorf32, MCPIP2" ENSG00000102053 "Zinc finger CCCH-type containing 12B" Q5HYM0 X 65366638-65507887 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 30 "Astrocytes: 90.4;Excitatory neurons: 232.1;Inhibitory neurons: 219.8;Microglial cells: 128.4;Oligodendrocyte precursor cells: 253.8;Oligodendrocytes: 258.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000836 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "Golgi apparatus, Vesicles" "HPA000836: AB_2217374" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (1.38e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-1)" "unprognostic (7.44e-3)" "unprognostic (7.86e-3)" "unprognostic (5.46e-2)" "unprognostic (3.32e-1)" "unprognostic (5.76e-2)" "unprognostic (1.12e-3)" "unprognostic (1.28e-1)" "unprognostic (2.61e-1)" "unprognostic (1.11e-2)" "unprognostic (5.08e-2)" "unprognostic (1.45e-2)" "unprognostic (1.71e-2)" 0.6 0.5 2.4 0.4 2.7 0.2 0.5 2.1 2.7 1.3 0.8 1.3 0.6 1.3 0.5 0.3 1.3 0.6 0.6 2.7 1.6 0.7 0.5 0.5 0.5 1.1 1.4 1.7 0.4 1.6 2.2 0.0 0.9 1.1 0.6 1.9 0.6 1.1 0.2 0.3 0.9 0.9 1.3 0.4 0.8 0.2 2.1 0.9 1.0 0.3 0.3 1.0 0.9 2.3 0.1 0.2 2.1 0.3 0.0 0.0 0.2 0.5 1.1 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.0 0.3 0.5 0.0 0.0 0.3 1.5 0.7 1.2 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.4 0.0 1.7 0.4 1.7 0.0 0.0 0.9 0.2 0.8 1.2 0.4 1.0 0.1 0.4 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.2 0.0 0.5 0.0 0.0 0.4 0.7 0.2 0.3 0.4 0.7 1.3 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.4 2.7 2.1 2.7 2.7 1.6 1.1 1.4 0.9 1.3 2.1 2.3 0.2 6.4 0.5 90.4 1.3 0.0 0.5 0.0 1.2 2.7 0.1 0.6 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.7 0.0 0.2 0.2 0.7 1.3 0.5 4.2 0.0 232.1 0.2 0.2 1.4 0.0 0.1 0.0 0.6 0.7 0.7 0.1 1.7 219.8 1.3 0.0 0.0 0.3 0.2 2.5 0.0 0.0 128.4 0.1 1.0 0.0 253.8 258.0 0.2 0.6 4.1 0.3 0.3 1.0 0.4 0.0 1.5 0.0 2.1 1.1 0.0 0.1 0.1 0.4 0.0 0.4 0.5 1.0 0.1 ZC3H14 "FLJ11806, NY-REN-37, UKp68" ENSG00000100722 "Zinc finger CCCH-type containing 14" Q6PJT7 14 88562970-88627596 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 173.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1282.6;Late spermatids: 460.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049798, HPA053510" Enhanced Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Nucleoli, Nucleoli rim" "HPA049798: AB_2680888, HPA053510: AB_2682174" "unprognostic (5.80e-3)" "unprognostic (2.25e-1)" "unprognostic (1.35e-2)" "unprognostic (7.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-1)" "unprognostic (6.47e-3)" "unprognostic (9.57e-2)" "unprognostic (7.21e-3)" "unprognostic (2.77e-3)" "unprognostic (4.83e-2)" "unprognostic (1.50e-2)" "prognostic favorable (7.08e-4)" "unprognostic (2.09e-1)" "unprognostic (8.23e-2)" "unprognostic (3.71e-1)" "unprognostic (4.25e-2)" 20.9 21.0 9.5 16.3 10.7 23.6 22.5 26.9 14.9 23.7 38.3 26.9 19.7 25.7 25.1 20.2 27.7 18.7 24.7 10.8 8.1 24.3 43.3 24.2 18.2 5.5 5.1 26.1 37.4 33.2 24.3 23.0 6.8 23.6 31.2 41.1 31.4 23.6 30.2 21.4 21.2 28.2 4.4 15.7 21.6 173.6 9.0 20.0 32.2 25.1 23.6 22.1 19.5 13.1 39.5 75.4 64.7 54.8 50.8 48.6 68.3 58.6 54.2 85.2 74.7 55.3 63.2 55.1 41.9 61.4 46.3 44.4 46.8 55.7 115.9 43.4 34.7 26.7 51.6 42.5 51.2 57.3 34.3 39.2 65.2 68.2 66.9 53.3 56.7 47.2 54.2 21.0 75.8 86.3 52.8 28.1 39.9 60.8 64.1 46.1 83.9 23.1 54.3 68.2 45.6 37.0 75.2 75.4 37.3 54.3 75.3 36.3 39.2 101.3 65.1 43.1 59.2 29.3 30.0 61.7 49.0 27.1 48.0 19.1 20.7 29.4 18.9 25.3 20.4 16.8 18.0 20.8 22.1 15.4 17.2 16.9 3.8 25.9 29.6 12.5 17.2 17.4 9.5 10.7 26.9 14.9 10.8 8.1 5.5 5.1 6.8 4.4 9.0 13.1 25.2 121.8 57.0 38.2 18.1 22.7 24.5 25.2 21.1 61.2 27.0 24.9 22.6 28.6 37.6 20.2 77.2 49.2 25.4 28.4 35.2 25.6 1282.6 53.0 46.6 28.7 31.8 17.1 88.8 23.0 27.4 30.5 20.9 34.3 45.6 51.8 24.3 38.1 20.3 65.6 65.5 31.4 34.6 14.9 16.3 460.1 39.4 19.6 5.4 34.7 20.0 33.6 18.6 64.3 62.9 22.0 16.4 47.4 18.6 26.0 27.4 32.4 53.0 78.9 13.1 46.6 35.4 217.9 81.5 23.0 19.7 40.6 20.1 39.2 32.8 16.3 ZCCHC2 "C18orf49, FLJ20222, FLJ20281, KIAA1744" ENSG00000141664 "Zinc finger CCHC-type containing 2" Q9C0B9 18 62523025-62587709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 143.8;Late spermatids: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040943 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA040943: AB_10795496" "unprognostic (9.32e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (4.07e-2)" "unprognostic (4.79e-2)" "unprognostic (2.60e-1)" "unprognostic (1.93e-1)" "unprognostic (8.25e-2)" "unprognostic (2.32e-2)" "unprognostic (1.30e-1)" "unprognostic (5.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.72e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 10.7 5.5 6.2 5.8 6.6 26.5 9.1 9.3 8.2 6.7 6.0 7.1 6.7 6.3 5.9 5.5 7.8 8.6 8.5 5.5 6.9 5.5 23.3 10.2 7.0 7.2 6.8 8.0 6.2 5.8 8.0 8.1 6.7 7.3 5.4 10.0 37.2 5.3 12.2 11.6 7.5 5.8 5.3 9.0 6.4 12.0 6.6 7.6 7.3 7.3 6.3 7.9 6.5 11.5 8.0 6.8 5.8 11.5 17.1 7.3 10.9 4.5 6.7 10.5 10.4 3.7 4.8 22.4 5.8 7.4 8.6 13.2 18.6 9.9 4.3 15.5 8.8 5.9 15.6 25.2 5.9 11.4 8.3 7.2 12.6 6.7 12.3 7.6 19.9 9.9 6.4 7.3 3.5 6.5 7.5 4.8 3.7 5.8 6.7 9.7 6.1 0.1 7.3 8.0 7.2 4.5 7.5 16.8 6.6 10.2 5.9 8.9 8.6 10.3 7.0 4.1 6.5 2.8 5.8 9.4 7.6 4.7 3.9 0.0 0.3 0.8 0.5 0.5 0.4 0.1 0.3 0.4 0.1 0.4 0.6 0.4 1.5 0.2 0.1 0.3 0.4 0.1 6.2 6.6 9.3 8.2 5.5 6.9 7.2 6.8 6.7 5.3 6.6 11.5 23.1 25.6 18.8 28.1 10.8 26.6 16.9 7.5 10.8 33.1 15.2 13.2 18.8 20.0 12.4 16.5 54.2 7.4 33.6 10.2 3.9 6.8 143.8 24.1 12.3 28.8 12.6 8.2 48.5 6.2 10.9 9.7 10.2 27.5 2.5 4.4 17.5 35.4 14.1 43.7 33.9 15.5 2.0 44.4 22.0 158.6 8.1 30.6 7.2 29.0 11.9 7.7 9.2 37.2 51.7 5.1 9.1 7.9 10.7 16.5 8.4 5.3 10.8 19.5 6.6 15.6 15.0 16.3 15.2 15.3 18.5 6.8 22.6 5.6 11.5 12.2 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 15.6 14.9 17.8 10.2 18.5 6.8 16.3 20.3 21.9 15.0 16.4 17.1 14.3 16.4 18.5 19.9 12.2 9.9 22.1 18.1 16.5 25.1 30.3 20.8 11.3 17.2 17.8 15.9 22.8 25.5 16.7 21.6 16.4 18.3 17.3 17.4 24.2 12.1 25.8 13.1 14.7 16.6 16.1 14.5 24.1 17.3 18.8 12.6 16.0 27.9 15.1 17.1 15.3 16.7 50.7 57.4 37.9 47.1 58.7 40.4 38.7 54.6 72.1 61.2 58.4 45.7 43.6 44.4 60.1 79.8 53.4 58.0 48.2 76.7 54.2 43.7 56.0 28.5 39.8 44.3 47.4 34.0 39.7 45.7 49.8 71.6 51.3 66.3 63.9 40.4 23.1 32.8 79.0 48.4 51.8 46.0 29.9 45.8 49.5 34.0 38.6 40.9 51.9 23.2 18.4 25.9 33.2 33.7 30.6 37.7 44.6 32.9 39.6 38.2 35.0 25.0 64.7 29.2 53.0 26.9 44.1 51.7 20.7 0.3 11.1 11.1 7.2 11.9 8.1 9.0 12.5 11.5 15.7 10.6 10.0 10.1 0.5 14.5 11.8 12.0 11.1 6.8 17.8 18.5 20.3 21.9 18.1 16.5 17.2 17.8 16.4 16.1 18.8 16.7 6.2 19.2 23.1 3.9 9.0 5.2 18.9 31.8 14.8 15.8 13.6 9.3 10.1 14.3 27.6 12.9 4.2 39.8 10.3 11.5 25.4 35.5 24.8 7.0 13.3 11.3 7.2 11.6 8.2 32.3 67.2 13.7 10.2 10.9 7.0 13.3 7.5 19.5 24.6 13.5 9.2 18.9 28.5 7.3 5.9 7.6 8.7 9.3 3.6 9.4 18.4 14.9 15.5 11.1 8.4 31.5 12.1 3.8 17.1 20.0 18.9 22.2 8.3 13.0 6.6 5.2 12.2 20.1 12.9 13.8 4.3 37.9 7.2 10.9 20.9 19.3 ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 66.0;Oligodendrocytes: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavorable (9.77e-5)" "prognostic unfavorable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 28.2 12.0 39.2 10.2 66.6 5.4 24.3 46.5 52.5 19.1 23.3 22.0 31.6 11.8 11.7 15.6 12.1 15.3 15.5 39.2 49.0 37.1 40.1 26.7 3.3 60.5 58.2 11.2 25.9 25.2 11.4 17.2 52.5 18.8 24.9 6.0 21.1 11.3 13.4 35.3 34.0 15.3 44.8 3.9 19.5 4.1 57.8 3.6 13.8 11.3 6.6 23.8 14.5 78.6 45.9 23.8 33.2 67.5 112.4 87.7 27.0 44.3 50.6 20.9 26.0 37.6 58.4 1.6 73.7 47.6 54.0 30.4 38.0 44.6 30.0 2.6 23.7 9.2 24.0 50.1 44.4 6.1 15.7 96.0 71.1 34.0 50.1 36.5 39.9 15.0 10.1 17.6 34.0 40.0 8.8 11.4 18.0 102.3 40.4 8.2 21.4 27.1 30.1 25.2 26.3 22.0 12.7 64.7 20.5 38.9 27.6 10.1 32.8 21.1 7.3 50.0 36.3 16.5 12.7 5.5 37.9 25.1 10.8 0.0 2.2 1.8 3.0 2.0 3.7 2.7 3.6 2.9 2.4 1.5 4.5 2.6 0.0 2.5 5.2 5.1 1.8 2.1 39.2 66.6 46.5 52.5 39.2 49.0 60.5 58.2 52.5 44.8 57.8 78.6 66.0 22.4 28.6 4.6 2.8 18.6 12.4 12.8 13.1 9.1 16.8 15.1 4.6 17.2 15.9 46.0 2.1 5.6 2.7 20.1 3.9 18.6 1.8 23.8 16.9 16.6 18.0 4.2 10.5 19.8 19.1 32.7 18.3 59.7 2.5 11.5 7.9 43.7 4.9 1.7 11.8 23.2 10.2 3.5 12.2 2.0 12.2 3.9 10.6 7.5 0.3 1.5 1.0 9.5 118.2 33.5 14.6 7.5 7.7 39.1 51.0 25.8 7.2 2.8 0.0 9.5 11.1 8.4 8.7 16.9 19.2 10.3 5.1 7.5 27.2 22.1 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 144.0;Proximal enterocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA035159: AB_2674499, HPA035160: AB_10670697" "unprognostic (3.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.77e-3)" "unprognostic (2.59e-1)" "unprognostic (2.97e-1)" "unprognostic (6.85e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (7.36e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.38e-4)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-3)" "unprognostic (1.32e-1)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" 28.5 26.6 33.2 20.7 34.3 38.2 28.3 34.4 43.7 38.2 27.4 41.6 41.5 29.7 18.1 48.8 28.5 20.0 28.1 33.3 34.0 44.1 64.5 32.3 28.4 37.2 33.3 29.0 40.7 26.8 36.2 17.4 34.3 31.3 25.0 10.8 27.7 17.6 34.3 42.5 45.4 15.9 33.1 45.9 37.4 15.6 34.3 37.9 49.8 15.5 23.3 33.0 35.5 37.5 23.0 14.4 17.2 23.7 17.6 18.5 23.5 22.8 26.3 32.1 31.7 34.8 18.9 16.5 23.0 39.2 26.0 15.5 15.4 28.9 25.5 27.8 25.2 41.8 25.6 30.3 36.3 22.9 45.3 15.3 62.2 31.9 75.0 17.7 21.2 40.0 25.0 38.9 31.9 40.0 37.9 47.9 8.9 31.7 17.5 22.4 8.3 31.6 29.6 17.7 33.7 16.3 10.9 17.3 24.8 19.3 15.4 47.3 22.5 32.2 29.5 37.2 33.3 20.2 6.6 34.1 31.5 44.2 25.6 30.8 34.8 48.6 49.1 46.0 42.5 43.6 44.2 48.0 26.7 53.0 39.9 48.9 58.3 53.5 38.3 33.5 51.6 44.3 33.2 34.3 34.4 43.7 33.3 34.0 37.2 33.3 34.3 33.1 34.3 37.5 30.4 22.4 21.2 17.6 43.5 27.1 26.3 34.0 19.9 14.9 37.1 33.7 12.7 44.3 24.5 20.2 14.6 26.9 52.4 144.0 56.7 44.1 4.9 14.6 17.7 26.4 40.2 15.2 17.8 66.0 24.3 19.6 42.3 20.7 32.4 11.6 23.6 39.4 34.9 8.4 16.1 67.5 36.7 32.4 31.3 7.8 32.0 35.6 35.6 5.6 24.4 21.5 44.3 6.0 15.3 60.3 101.1 29.7 39.5 25.1 170.6 79.5 13.8 17.2 26.3 15.9 28.7 6.2 22.9 27.6 36.1 51.3 46.7 27.8 54.4 28.8 ZFAND5 "ZA20D2, ZFAND5A, ZNF216" ENSG00000107372 "Zinc finger AN1-type containing 5" O76080 9 72351413-72365235 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 591.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 450.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018129, HPA077824" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nuclear bodies, Cytosol" "HPA018129: AB_1859012, HPA077824: " "unprognostic (1.97e-1)" "unprognostic (5.79e-2)" "unprognostic (1.91e-1)" "prognostic favorable (4.43e-4)" "unprognostic (1.53e-1)" "unprognostic (2.24e-1)" "unprognostic (3.39e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.39e-1)" "unprognostic (3.34e-1)" "unprognostic (2.47e-1)" "unprognostic (3.90e-2)" "unprognostic (6.85e-2)" "unprognostic (3.92e-2)" "unprognostic (3.86e-2)" "unprognostic (7.03e-2)" 312.2 187.7 99.9 55.3 112.7 145.7 150.0 105.5 136.0 97.6 70.9 88.1 39.4 91.0 115.7 99.8 120.6 87.3 117.7 103.9 107.8 114.9 204.7 108.5 46.9 93.9 113.3 250.4 73.6 69.1 138.8 79.2 105.6 76.8 49.2 50.7 69.8 121.4 591.1 75.4 69.0 94.9 100.5 60.4 95.5 88.5 105.9 52.3 79.2 273.9 59.1 108.9 87.1 110.8 115.9 113.0 138.8 59.4 156.5 77.3 104.3 131.9 178.9 71.1 55.1 14.5 112.6 60.4 81.3 194.5 105.2 122.4 305.1 50.4 103.4 450.1 43.1 53.5 57.7 70.1 120.4 74.7 71.1 99.0 87.6 72.7 79.2 156.3 122.1 60.4 49.8 82.1 82.6 31.3 96.3 38.8 178.9 107.2 74.3 74.1 72.4 70.5 218.4 109.3 101.2 86.4 85.2 91.2 117.2 142.1 42.1 64.3 97.1 57.4 71.7 104.7 90.9 113.9 110.3 38.1 77.2 49.1 146.3 39.0 35.9 37.3 11.2 52.1 12.0 17.0 14.6 14.1 33.6 15.1 13.2 12.2 27.7 19.2 81.6 6.2 11.2 23.9 99.9 112.7 105.5 136.0 103.9 107.8 93.9 113.3 105.6 100.5 105.9 110.8 370.7 176.3 192.1 102.8 125.8 339.2 573.2 130.6 376.7 93.9 267.0 207.1 322.6 92.9 132.6 132.4 75.0 145.1 118.6 213.3 148.7 145.8 91.8 257.1 291.9 195.3 136.7 155.6 45.7 142.6 164.8 270.8 145.2 527.6 109.2 116.1 97.5 308.3 198.0 40.4 38.6 119.8 126.1 290.6 320.1 44.5 118.4 470.1 208.1 31.9 268.8 84.2 53.5 38.7 67.2 185.9 221.3 93.3 149.3 329.9 87.2 127.1 109.2 70.6 85.5 674.9 285.2 148.7 116.4 298.1 291.2 226.3 165.5 102.9 109.4 528.2 ZFP41 "FLJ00028, FLJ38705, ZNF753" ENSG00000181638 "ZFP41 zinc finger protein" Q8N8Y5 8 143246821-143262705 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (4.92e-2)" "unprognostic (7.18e-2)" "unprognostic (3.53e-2)" "unprognostic (4.16e-3)" "unprognostic (2.98e-1)" "unprognostic (1.55e-2)" "unprognostic (6.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.44e-2)" "unprognostic (3.20e-1)" 2.9 3.5 5.4 2.3 6.6 1.5 2.8 2.8 6.9 3.6 0.0 3.8 3.4 4.2 1.4 2.9 4.1 1.9 3.1 4.9 6.6 3.9 3.4 2.2 2.6 7.8 5.6 5.3 3.5 4.0 5.3 1.1 5.7 3.7 1.5 2.4 4.8 2.6 3.2 4.9 3.6 2.0 2.4 3.2 3.6 6.3 8.2 2.4 4.1 1.8 2.1 3.4 3.0 9.7 6.7 10.5 4.5 6.0 5.1 3.9 5.3 4.0 2.1 7.6 5.2 5.2 5.5 3.7 5.8 5.2 7.7 5.4 4.9 5.2 3.7 5.9 6.0 4.7 5.6 4.1 7.1 1.8 2.8 4.1 7.2 4.9 7.2 5.2 3.6 2.6 10.1 3.5 3.6 12.0 5.0 2.0 6.7 8.2 10.3 2.6 3.7 1.3 3.3 6.0 5.7 7.8 11.2 3.0 5.9 3.8 7.7 3.6 3.8 5.7 10.2 4.5 6.4 5.6 4.6 1.7 5.1 4.5 7.7 0.0 0.1 0.0 0.3 0.2 0.5 0.1 0.2 0.2 0.1 0.2 0.4 0.3 0.0 0.1 0.0 0.9 0.2 0.2 5.4 6.6 2.8 6.9 4.9 6.6 7.8 5.6 5.7 2.4 8.2 9.7 1.6 0.0 2.0 2.9 2.3 1.1 0.7 0.8 0.6 2.5 2.3 1.9 3.2 5.7 1.1 3.7 6.2 0.3 0.8 3.7 1.9 1.9 1.5 1.8 2.3 1.6 3.0 0.8 2.2 0.9 1.1 1.6 2.6 1.2 0.0 2.7 2.5 3.9 1.2 6.7 3.4 2.4 2.0 2.2 0.5 2.6 1.2 1.5 1.8 1.0 0.9 2.5 2.1 1.5 4.4 1.6 4.1 2.2 1.6 0.5 3.4 1.4 3.2 2.0 0.0 1.6 1.9 7.9 3.7 1.8 0.3 0.3 0.9 1.6 3.4 0.4 ZFP82 "KIAA1948, MGC45380, ZNF545" ENSG00000181007 "ZFP82 zinc finger protein" Q8N141 19 36383120-36418644 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 33.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051669, HPA060470" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA051669: AB_2732568, HPA060470: AB_2684290" "unprognostic (1.52e-1)" "unprognostic (2.38e-2)" "unprognostic (6.03e-2)" "unprognostic (4.14e-4)" "unprognostic (9.63e-2)" "unprognostic (9.17e-4)" "unprognostic (1.91e-2)" "unprognostic (2.01e-1)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (2.61e-3)" "unprognostic (4.91e-1)" "unprognostic (3.69e-2)" "unprognostic (6.00e-2)" "unprognostic (3.21e-2)" "unprognostic (3.81e-2)" "unprognostic (3.05e-1)" 2.1 2.1 4.5 1.3 4.8 0.7 2.7 6.4 6.8 3.6 3.4 2.7 0.7 3.1 4.2 0.9 3.0 1.9 2.6 4.5 4.7 2.3 0.6 1.5 2.6 3.9 4.3 4.4 1.2 2.7 3.1 2.4 3.9 2.7 1.1 5.1 1.4 1.8 0.8 0.9 1.7 2.2 3.9 2.7 1.3 2.5 4.3 2.9 4.1 1.1 2.6 3.0 2.3 4.8 0.1 2.8 8.6 7.3 2.0 2.8 2.7 2.9 3.2 5.0 6.3 1.3 1.0 7.0 5.5 3.2 4.8 0.3 0.0 0.8 6.1 4.6 4.0 7.2 1.5 1.6 4.9 0.0 5.7 3.8 1.1 3.4 0.9 0.0 2.2 9.8 0.1 0.1 5.3 0.0 12.2 0.1 4.8 0.0 1.2 8.8 5.2 1.5 2.8 3.9 0.4 8.6 0.0 0.6 4.0 6.4 1.7 4.1 0.5 2.1 2.8 4.3 5.6 5.6 3.7 10.0 0.1 0.1 4.6 0.2 0.5 0.7 2.7 0.5 2.6 4.8 2.6 3.0 1.3 4.3 4.0 3.6 0.4 2.5 0.6 1.6 1.7 1.5 4.5 4.8 6.4 6.8 4.5 4.7 3.9 4.3 3.9 3.9 4.3 4.8 3.6 0.0 6.4 7.5 9.0 1.0 2.3 2.4 1.8 20.3 3.7 3.6 4.6 1.5 3.4 5.5 22.9 7.8 3.5 0.1 9.8 6.0 11.2 2.2 4.6 5.9 3.0 1.7 16.4 1.4 5.9 5.5 0.5 1.7 6.3 11.4 3.3 0.6 4.4 33.7 19.0 0.3 6.1 2.6 3.4 2.5 5.9 3.5 5.4 6.5 1.4 7.9 3.1 21.1 22.1 1.1 0.2 7.5 3.2 1.9 0.4 4.8 6.1 11.8 19.7 4.7 5.0 17.5 9.1 0.6 0.6 1.4 5.7 7.6 0.9 1.2 ZFP90 "KIAA1954, NK10, ZNF756" ENSG00000184939 "ZFP90 zinc finger protein" Q8TF47 16 68530090-68576072 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029017 Uncertain Supported "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Vesicles, Plasma membrane, Centrosome" "HPA029017: AB_10669653" "unprognostic (3.27e-1)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.68e-3)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (7.33e-2)" "unprognostic (1.35e-3)" "unprognostic (3.43e-1)" "prognostic favorable (1.78e-4)" "unprognostic (1.47e-2)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (9.60e-2)" 7.0 6.3 19.4 7.2 18.6 6.1 11.1 27.0 31.1 11.7 9.9 8.2 2.9 10.8 12.2 5.9 9.5 6.5 8.0 18.2 18.1 8.6 5.4 6.7 9.5 15.2 14.6 12.7 7.4 15.7 13.5 5.8 15.3 9.2 6.2 12.7 6.3 8.8 8.2 9.3 7.3 9.3 11.0 10.5 8.1 9.7 18.2 13.4 8.2 9.0 11.3 7.5 8.0 20.3 10.6 11.4 20.9 19.9 18.1 19.2 9.7 9.7 11.0 13.2 15.2 8.0 7.0 11.5 12.7 12.6 11.1 9.7 12.9 12.5 15.0 10.1 4.7 3.0 2.2 13.4 14.0 0.0 10.3 17.2 20.2 12.1 16.8 23.5 10.7 21.2 5.8 4.1 16.3 18.8 11.6 10.7 7.8 6.3 8.5 21.0 6.5 7.6 9.0 7.2 23.5 17.9 28.1 2.1 10.5 15.4 16.8 14.9 8.4 12.2 7.2 10.4 5.8 8.1 15.9 14.0 4.1 4.0 9.9 7.9 1.5 2.5 5.2 1.6 6.7 4.5 4.9 6.0 2.0 3.3 6.7 5.9 0.3 4.3 1.0 2.3 5.8 2.7 19.4 18.6 27.0 31.1 18.2 18.1 15.2 14.6 15.3 11.0 18.2 20.3 13.1 19.2 8.9 18.6 15.1 3.4 6.4 10.5 14.8 21.1 8.5 9.4 10.5 10.0 9.0 20.2 14.6 3.4 11.8 1.5 7.9 10.2 20.6 9.8 14.4 10.9 16.1 13.2 34.0 6.1 1.7 14.7 5.1 6.5 12.0 30.3 11.0 5.2 6.9 18.5 41.4 4.7 4.1 7.9 5.7 13.2 16.4 8.3 3.6 11.2 6.4 13.0 19.6 31.2 35.5 6.5 3.2 17.7 7.2 5.9 1.3 8.1 24.2 17.3 0.0 12.4 11.0 12.1 19.1 8.6 4.5 1.4 18.7 13.7 4.5 4.0 ZFPM1 "FOG, FOG1, ZC2HC11A, ZNF89A" ENSG00000179588 "Zinc finger protein, FOG family member 1" Q8IX07 16 88453280-88537031 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 35.3;Muller glia cells: 58.0;Theca cells: 37.4" "Cancer enhanced" "Detected in all" "stomach cancer: 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 19.3;K-562: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046603 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA046603: AB_2679718" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (3.08e-2)" "unprognostic (3.32e-2)" "unprognostic (1.13e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-1)" "unprognostic (7.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (5.58e-2)" "unprognostic (3.05e-2)" "unprognostic (2.49e-4)" "unprognostic (1.99e-2)" "unprognostic (3.32e-1)" "unprognostic (4.89e-2)" "prognostic favorable (4.24e-4)" 2.1 2.5 4.8 1.9 2.4 9.2 1.9 5.7 5.8 2.3 4.2 1.7 12.4 2.2 1.0 1.8 4.0 1.5 4.8 5.8 2.1 3.7 8.6 2.1 2.7 3.5 3.2 2.2 10.4 1.4 5.6 0.8 2.6 3.2 0.8 0.7 2.8 1.3 1.6 3.7 6.8 0.2 1.6 4.9 13.7 5.7 3.3 1.5 4.0 0.3 1.2 2.3 2.0 1.6 1.4 3.8 2.8 5.9 0.5 0.1 11.9 4.0 0.5 1.3 0.4 12.1 1.5 5.9 3.0 0.6 1.4 9.5 0.1 3.3 0.3 4.6 2.5 19.3 8.1 10.7 2.1 1.1 6.2 1.3 2.1 1.4 0.5 1.4 1.3 1.6 29.2 0.4 1.0 7.3 6.9 7.0 1.9 9.3 3.2 2.0 1.3 2.9 1.3 4.8 7.7 12.8 4.9 0.3 3.9 1.4 3.1 3.1 4.8 4.9 3.1 2.2 0.8 1.4 1.0 0.5 1.4 2.3 4.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 2.4 5.7 5.8 5.8 2.1 3.5 3.2 2.6 1.6 3.3 1.6 16.7 3.2 2.2 12.4 4.8 0.9 6.1 0.7 0.0 20.7 13.5 25.8 17.2 5.7 0.4 1.8 29.2 0.4 27.5 10.8 1.9 1.3 0.7 24.1 23.7 6.3 6.0 4.8 6.8 5.1 0.2 10.9 14.3 20.1 0.0 16.0 5.0 8.8 0.9 35.3 8.0 6.7 0.0 5.3 1.2 1.1 0.9 7.5 1.8 8.4 1.6 58.0 2.1 5.5 13.4 2.9 6.2 1.5 9.5 1.4 1.3 1.3 0.4 23.9 0.0 16.1 12.4 0.7 1.0 1.9 1.4 0.3 9.6 37.4 5.2 2.1 ZFYVE27 "FLJ32919, SPG33" ENSG00000155256 "Zinc finger FYVE-type containing 27" Q5T4F4 10 97737121-97760907 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037523, HPA069876" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" Cytosol "HPA037523: AB_10672351, HPA069876: AB_2686218" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.30e-2)" "unprognostic (2.48e-2)" "unprognostic (7.15e-2)" "unprognostic (2.05e-3)" "unprognostic (5.24e-2)" "unprognostic (3.38e-3)" "prognostic favorable (7.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.26e-2)" "prognostic favorable (7.80e-4)" 14.4 27.9 33.1 12.9 32.1 23.2 15.8 29.2 35.9 20.6 34.8 25.6 24.8 16.5 22.9 16.5 20.3 12.1 17.8 35.5 33.6 28.3 32.6 17.7 16.1 32.6 31.4 25.9 23.7 19.2 38.3 9.5 33.2 22.0 16.3 28.4 18.9 10.3 12.8 18.2 30.6 8.5 29.1 29.1 19.8 23.0 33.5 12.7 20.4 5.9 13.1 16.8 17.0 32.4 17.7 21.4 12.6 28.1 14.1 9.8 17.2 17.7 18.5 20.3 19.7 19.1 35.9 27.2 19.8 12.8 25.9 38.8 18.4 17.2 10.6 28.3 18.6 12.9 23.1 18.1 18.1 20.9 24.9 16.0 20.4 19.9 15.2 32.4 11.5 22.5 19.6 17.9 15.3 13.8 16.9 39.4 10.3 15.3 16.4 19.2 12.7 13.0 19.5 10.8 10.1 19.7 11.9 9.9 47.2 11.5 21.8 20.5 12.4 10.2 11.9 15.6 34.2 20.6 18.6 14.3 25.3 26.5 11.9 4.8 5.8 9.3 9.6 6.2 8.2 7.1 6.6 7.9 5.4 6.7 7.5 8.3 8.2 6.8 9.2 5.6 9.5 8.3 33.1 32.1 29.2 35.9 35.5 33.6 32.6 31.4 33.2 29.1 33.5 32.4 10.0 3.2 11.4 14.0 22.1 8.2 12.8 11.3 18.8 29.9 11.1 8.9 7.2 14.3 9.7 14.7 58.4 7.4 21.2 33.9 7.9 14.9 5.2 14.3 7.8 11.0 20.3 14.3 33.6 16.0 5.7 10.1 19.4 11.4 14.0 17.3 10.8 10.9 8.2 37.0 35.2 15.6 14.2 8.8 5.7 1.5 9.6 11.0 10.6 16.9 11.2 14.8 15.5 12.5 20.2 13.9 26.1 9.1 13.4 13.8 35.5 8.6 16.6 43.7 19.7 6.7 9.9 8.9 7.6 10.4 5.5 13.5 17.9 10.9 14.7 17.7 ZFYVE28 "KIAA1643, lst-2" ENSG00000159733 "Zinc finger FYVE-type containing 28" Q9HCC9 4 2269582-2418651 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 49.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.9;Inhibitory neurons: 93.2;NK-cells: 48.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.8;T-cells: 1.9" "Cell line enhanced" "Detected in many" "HMC-1: 12.6;NB-4: 14.2;U-266/70: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038175, HPA057587" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: NB-4 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA038175: AB_10697244, HPA057587: AB_2683477" "unprognostic (1.59e-1)" "unprognostic (4.60e-2)" "unprognostic (7.68e-2)" "unprognostic (3.08e-3)" "unprognostic (9.89e-3)" "unprognostic (3.79e-2)" "unprognostic (3.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.64e-2)" "prognostic favorable (1.35e-6)" "unprognostic (6.05e-2)" "unprognostic (5.27e-2)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" 5.5 8.7 4.6 3.1 7.5 2.1 5.4 49.9 18.0 5.5 0.5 8.0 6.1 4.8 1.6 4.7 5.4 3.4 3.9 7.3 0.3 8.7 6.5 6.2 4.0 9.4 6.9 4.5 5.0 4.3 10.8 1.0 7.4 4.0 2.8 4.0 5.5 2.8 2.9 5.4 8.8 1.5 1.0 6.7 7.2 8.1 5.0 2.6 7.7 1.8 2.0 4.8 4.6 6.2 0.9 1.2 0.2 4.2 2.4 0.8 0.2 2.1 3.5 1.1 0.3 0.1 7.6 0.0 2.2 3.7 2.9 4.4 1.4 0.3 0.7 11.7 1.5 0.3 5.3 0.3 4.8 0.8 12.6 3.3 0.7 1.3 0.1 7.7 3.5 1.1 2.2 9.2 1.0 2.6 0.1 14.2 0.2 2.4 9.3 0.0 0.0 4.7 1.7 0.6 6.6 0.5 2.1 0.1 1.2 0.1 2.8 0.3 0.6 2.0 0.1 6.2 0.2 14.8 11.7 0.2 6.0 2.8 2.0 0.4 0.2 0.0 1.9 0.0 0.8 0.4 1.0 1.3 0.3 1.8 1.3 1.4 0.0 0.2 0.1 0.1 1.9 0.5 4.6 7.5 49.9 18.0 7.3 0.3 9.4 6.9 7.4 1.0 5.0 6.2 12.2 0.0 1.7 41.4 3.7 5.9 3.4 2.1 5.7 12.2 7.6 6.2 3.4 7.2 2.9 11.0 18.8 0.3 25.4 32.3 7.9 3.4 29.1 5.1 4.8 8.0 2.4 1.3 133.9 2.3 0.3 3.6 11.7 6.3 8.9 2.6 5.3 3.7 1.9 8.4 93.2 7.8 2.0 2.2 33.0 8.9 1.5 5.1 7.2 32.8 4.0 1.6 48.4 23.6 36.4 2.6 16.8 2.2 9.8 1.7 18.1 4.2 3.0 17.8 0.0 2.3 3.0 3.1 8.0 6.2 4.8 0.3 31.6 8.2 6.6 5.4 ZKSCAN1 "KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33" ENSG00000106261 "Zinc finger with KRAB and SCAN domains 1" P17029 7 100015572-100041689 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006672 Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 15: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Mitochondria" "HPA006672: AB_1080707" "unprognostic (2.58e-1)" "unprognostic (1.59e-2)" "unprognostic (3.57e-2)" "unprognostic (4.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.24e-2)" "unprognostic (1.47e-2)" "unprognostic (4.76e-3)" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.34e-3)" "unprognostic (8.59e-2)" "unprognostic (1.27e-3)" "unprognostic (7.75e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "unprognostic (9.09e-3)" 12.0 18.4 20.2 11.6 29.1 8.7 22.7 17.2 22.1 16.4 7.4 21.5 18.2 15.5 17.1 18.8 21.7 13.9 10.1 14.4 23.8 13.3 52.8 10.9 11.7 21.3 23.2 19.0 26.1 16.5 10.9 11.0 23.4 23.0 23.5 15.8 25.3 10.8 10.4 32.6 16.9 13.7 13.9 13.5 32.6 11.1 24.1 14.2 11.9 8.8 11.9 12.2 17.4 37.5 17.0 12.3 31.8 34.6 32.0 38.7 12.0 18.6 22.5 10.9 11.0 7.4 15.7 19.1 23.0 20.9 19.1 13.7 18.4 16.1 20.6 18.4 11.3 15.5 15.8 19.3 18.0 29.9 17.7 26.1 25.1 14.7 49.0 29.5 24.4 22.2 36.2 16.3 21.7 22.4 28.4 17.6 12.8 31.6 15.2 16.7 16.2 17.3 18.2 26.4 36.8 44.0 28.9 37.4 32.4 17.8 19.1 19.6 36.8 23.7 23.0 27.9 18.9 18.7 35.3 19.5 16.2 20.8 31.7 16.0 4.0 4.1 5.0 3.1 4.9 3.8 3.9 4.9 5.8 4.8 5.3 3.9 4.2 8.8 9.0 3.9 3.5 3.8 20.2 29.1 17.2 22.1 14.4 23.8 21.3 23.2 23.4 13.9 24.1 37.5 45.3 25.6 55.4 57.5 37.0 15.0 45.7 43.4 71.7 93.9 77.6 38.7 42.8 140.2 61.4 46.0 150.1 41.1 40.1 84.8 15.6 55.9 46.5 89.2 90.9 52.2 220.9 24.6 70.1 43.8 15.3 47.9 103.5 68.0 35.4 120.5 44.6 140.8 19.8 89.2 77.7 99.2 77.3 32.7 18.6 18.4 51.3 31.2 40.9 62.8 45.8 61.2 34.0 102.1 272.5 46.6 81.3 53.4 27.1 93.1 70.4 32.4 153.6 70.1 19.7 87.4 43.9 32.8 16.7 62.9 21.5 65.9 32.3 74.0 114.4 62.0 ZKSCAN2 "FLJ23199, ZNF694, ZSCAN34" ENSG00000155592 "Zinc finger with KRAB and SCAN domains 2" Q63HK3 16 25236001-25257845 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Cone photoreceptor cells: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049141 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus" "HPA049141: AB_2680652" "unprognostic (2.71e-1)" "unprognostic (4.99e-2)" "unprognostic (2.47e-1)" "unprognostic (6.57e-2)" "unprognostic (3.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.26e-1)" "unprognostic (5.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.14e-2)" "unprognostic (8.28e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.70e-6)" "unprognostic (2.33e-1)" "unprognostic (2.29e-1)" "unprognostic (1.97e-1)" "unprognostic (4.03e-2)" 1.2 1.3 2.2 0.9 2.0 1.9 1.7 2.0 1.9 2.1 0.7 1.3 0.6 2.3 1.2 0.6 1.7 1.0 1.9 2.1 2.6 1.5 1.6 1.2 1.2 2.0 2.2 3.8 1.1 2.9 1.6 1.6 2.3 1.6 1.0 4.1 1.2 1.7 3.2 0.6 1.0 1.9 1.8 1.1 1.1 4.2 3.0 2.4 2.1 4.6 1.1 1.2 0.9 2.4 2.0 1.9 8.6 5.4 3.4 3.2 3.5 2.1 3.2 3.1 3.0 5.0 1.4 6.5 2.2 2.5 3.4 1.4 5.8 2.8 3.7 3.6 3.9 3.8 3.4 7.7 4.5 3.1 1.9 4.3 3.3 2.9 4.9 3.2 2.4 4.6 7.0 3.1 2.9 2.0 7.7 3.3 4.7 0.7 1.8 9.0 6.3 1.4 2.5 2.8 6.8 6.8 2.6 2.3 2.3 4.1 2.8 5.0 2.4 5.0 3.3 2.0 3.3 4.1 3.6 7.5 1.7 2.5 3.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.4 0.0 0.2 0.0 0.1 2.2 2.0 2.0 1.9 2.1 2.6 2.0 2.2 2.3 1.8 3.0 2.4 1.2 16.0 2.3 4.2 2.4 0.8 2.7 1.3 0.6 7.4 2.0 1.9 3.8 0.0 0.6 1.8 14.6 3.4 1.5 1.1 0.0 1.6 4.4 2.4 3.9 2.1 4.9 0.4 3.3 0.9 2.1 2.5 0.5 2.9 1.3 7.2 0.7 3.2 1.6 6.7 4.9 1.7 2.0 2.4 1.5 2.1 5.0 1.3 1.8 2.8 1.7 4.1 2.1 1.5 4.1 2.2 0.8 3.8 4.1 2.5 1.1 1.4 2.3 8.9 0.0 3.6 1.9 11.4 8.2 1.0 0.6 4.1 1.5 3.9 1.3 1.4 ZMYM4 "KIAA0425, MYM, ZNF198L3, ZNF262" ENSG00000146463 "Zinc finger MYM-type containing 4" Q5VZL5 1 35268709-35422058 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 127.9;Inhibitory neurons: 136.5;Oligodendrocyte precursor cells: 174.4;Oligodendrocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051301, HPA054802" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "HPA051301: AB_2681431, HPA054802: AB_2682605" "unprognostic (8.95e-2)" "unprognostic (6.80e-2)" "unprognostic (1.51e-2)" "unprognostic (1.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (9.75e-9)" "unprognostic (9.76e-2)" "unprognostic (4.35e-3)" "unprognostic (4.44e-2)" "unprognostic (6.70e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.18e-1)" "unprognostic (2.04e-1)" "unprognostic (9.18e-2)" "unprognostic (2.21e-1)" 12.1 11.4 13.3 12.5 14.3 13.6 17.2 23.9 15.2 17.2 12.0 11.8 8.9 16.3 15.5 12.7 14.8 13.5 11.2 11.8 14.9 13.3 12.8 12.1 14.4 12.8 13.3 21.7 13.9 18.1 9.3 17.2 14.0 15.0 11.5 24.6 12.2 13.6 14.9 10.9 9.2 13.7 13.8 14.8 13.7 34.2 14.0 20.9 18.4 15.3 17.0 14.6 9.9 16.0 28.1 22.6 67.7 35.0 19.2 41.4 24.9 32.7 49.1 39.1 50.7 24.6 27.6 52.0 19.6 41.3 19.1 17.8 47.3 24.4 56.2 29.5 27.8 63.5 25.0 21.4 35.5 54.7 28.1 31.3 21.1 38.3 35.9 32.4 44.0 28.5 70.0 14.1 47.9 17.4 47.4 32.0 56.3 15.0 19.9 52.4 43.4 26.1 28.7 37.2 39.1 37.5 39.1 29.4 45.7 42.3 23.2 41.4 53.7 36.4 37.8 16.3 35.9 15.3 29.9 40.0 26.2 41.4 35.7 1.8 3.6 2.7 3.1 5.1 2.9 3.2 2.8 2.7 3.5 2.4 2.7 2.6 0.7 6.6 7.1 7.0 2.4 1.9 13.3 14.3 23.9 15.2 11.8 14.9 12.8 13.3 14.0 13.8 14.0 16.0 33.6 12.8 21.9 94.3 17.4 11.5 16.6 14.4 17.1 30.7 31.8 29.1 32.0 25.8 20.8 27.6 31.3 14.7 20.6 6.6 5.9 22.7 59.8 25.0 45.1 22.8 22.3 22.5 127.9 23.7 12.5 27.0 21.9 33.7 14.5 49.1 18.5 16.1 13.1 23.5 136.5 14.7 14.2 23.1 12.5 91.9 26.4 21.4 5.4 109.6 27.5 22.5 26.8 174.4 132.6 19.9 8.1 23.0 13.9 22.7 5.5 11.8 21.6 33.0 19.7 33.4 29.0 34.4 13.3 13.8 11.4 14.1 13.9 45.5 14.0 22.7 ZNF10 KOX1 ENSG00000256223 "Zinc finger protein 10" P21506 12 133130575-133159465 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 45.5;Excitatory neurons: 46.0;Inhibitory neurons: 48.4;Oligodendrocyte precursor cells: 54.3;Oligodendrocytes: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003204 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Plasma membrane" Nucleoplasm "HPA003204: AB_1080663" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (4.32e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (6.39e-3)" "unprognostic (4.02e-3)" "unprognostic (2.13e-1)" "unprognostic (3.35e-3)" "unprognostic (2.50e-2)" "unprognostic (3.94e-2)" "unprognostic (3.41e-1)" "unprognostic (1.52e-1)" "unprognostic (4.36e-2)" "unprognostic (5.13e-3)" 6.7 14.3 4.9 3.7 5.6 8.6 12.3 8.8 7.6 14.4 6.2 10.9 3.7 15.0 23.4 6.0 12.1 10.3 8.3 5.8 8.0 10.9 10.6 7.6 5.9 4.7 6.8 22.4 13.2 17.3 45.3 5.2 5.6 15.1 6.2 13.1 8.0 12.7 4.9 8.8 7.1 8.6 5.4 6.0 10.5 15.3 7.8 7.7 21.2 6.3 5.8 10.7 8.8 7.1 3.8 2.2 10.8 0.0 11.5 4.8 6.5 4.4 3.9 5.3 3.6 3.9 2.4 0.0 6.0 4.4 2.9 1.7 6.8 3.6 3.9 0.0 6.6 8.0 10.5 4.4 3.5 5.0 2.6 5.0 3.3 5.7 6.3 7.9 4.4 6.3 6.0 0.0 6.3 1.2 12.0 10.6 11.1 2.1 4.4 9.9 6.8 5.4 4.2 7.9 10.7 7.0 8.7 1.4 3.7 4.9 6.6 5.0 4.3 3.9 3.6 3.7 3.7 0.2 0.0 12.8 1.2 1.7 3.7 0.9 0.5 1.4 2.9 0.6 3.2 3.1 3.4 4.1 1.4 3.0 6.5 3.3 0.5 6.3 0.4 3.4 0.9 1.8 4.9 5.6 8.8 7.6 5.8 8.0 4.7 6.8 5.6 5.4 7.8 7.1 6.8 0.0 9.0 39.2 39.6 3.8 5.3 3.9 45.5 15.9 9.9 9.4 7.7 4.3 7.1 0.0 31.3 4.5 9.1 1.8 1.9 2.3 24.6 11.9 7.6 5.0 12.6 5.0 46.0 1.4 2.0 15.5 21.4 11.7 10.8 5.0 1.4 4.9 2.5 5.0 48.4 3.9 6.1 3.8 4.6 6.3 2.8 9.0 3.6 21.5 1.5 9.1 2.1 54.3 45.4 1.0 2.1 6.8 16.3 2.6 2.2 2.5 2.7 16.2 0.0 6.3 14.3 20.4 15.4 21.4 3.8 3.8 21.9 6.0 3.3 1.6 ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491141 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 392.5;tongue: 465.5" "Cell type enriched" "Detected in all" 9 "Cardiomyocytes: 1836.4" "Cancer enhanced" "Detected in all" "melanoma: 29.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 161.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoli "Nucleoplasm, Cytosol" "HPA054267: AB_2682431" "unprognostic (2.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.10e-2)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" "unprognostic (2.49e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-3)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-1)" "unprognostic (4.09e-3)" 32.4 11.2 20.8 14.3 29.8 24.4 17.9 19.0 28.1 18.0 109.2 19.7 10.0 15.9 17.3 18.5 12.7 17.2 175.6 23.3 22.6 16.5 8.7 20.9 17.5 23.6 29.1 15.9 10.3 17.8 10.3 12.9 22.5 20.9 13.9 22.0 12.9 14.7 392.5 11.7 13.3 23.0 20.8 17.1 12.8 14.3 27.4 15.6 13.2 465.5 18.6 14.6 9.1 27.7 27.2 15.1 29.0 33.5 86.8 68.5 16.1 21.7 22.2 19.6 20.5 33.9 7.8 17.8 19.0 27.7 22.8 31.8 28.3 23.4 29.5 29.0 13.1 34.7 37.9 13.6 23.2 43.1 20.2 55.4 17.8 28.0 32.6 19.5 32.3 23.2 43.0 2.7 36.9 11.9 16.2 13.3 11.0 26.1 15.1 15.2 54.3 10.8 12.1 31.5 16.5 10.2 45.0 22.8 28.7 23.4 20.0 30.0 42.2 20.8 32.5 26.1 32.3 14.8 32.2 76.5 18.4 33.6 37.6 86.8 63.8 27.1 15.6 52.3 13.5 21.8 13.0 13.3 35.6 26.8 11.3 10.6 161.0 12.5 66.8 36.0 13.0 18.0 20.8 29.8 19.0 28.1 23.3 22.6 23.6 29.1 22.5 20.8 27.4 27.7 58.0 134.6 107.7 46.0 49.6 38.5 57.9 41.9 44.3 58.5 50.9 46.0 1836.4 62.9 57.0 29.5 95.9 37.9 67.2 31.7 41.1 43.2 197.2 75.2 67.1 69.9 40.2 50.5 73.3 42.4 39.3 141.7 31.1 37.5 44.9 49.5 62.8 40.1 53.5 35.3 62.9 32.6 32.6 132.7 43.4 105.2 37.6 89.8 65.8 47.8 124.3 53.6 66.9 31.2 34.2 65.7 26.9 92.6 50.7 74.8 39.7 41.5 161.1 79.9 46.0 151.2 70.0 62.3 38.1 49.8 29.8 30.6 46.0 85.9 36.6 68.2 ZNF121 "D19S204, ZHC32, ZNF20" ENSG00000197961 "Zinc finger protein 121" P58317 19 9560329-9584504 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 68.2;RT4: 72.3" "Low region specificity" "Detected in all" HPA054961 Uncertain Approved Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 24: NB-4 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" Nucleoli "HPA054961: AB_2682651" "unprognostic (3.06e-1)" "unprognostic (9.38e-3)" "unprognostic (9.51e-2)" "unprognostic (7.49e-2)" "unprognostic (3.07e-2)" "unprognostic (3.91e-3)" "unprognostic (3.68e-2)" "unprognostic (1.76e-1)" "unprognostic (6.80e-3)" "prognostic favorable (6.59e-5)" "unprognostic (9.36e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.75e-3)" "unprognostic (2.83e-1)" "unprognostic (1.06e-1)" "prognostic favorable (5.75e-5)" 7.0 4.8 5.5 5.2 5.9 14.3 7.2 8.8 6.4 5.3 8.2 5.5 3.6 4.7 5.6 9.3 5.4 4.0 6.1 5.7 6.7 8.0 8.5 7.5 6.2 6.0 5.1 4.6 6.3 8.7 6.7 4.2 6.3 7.1 5.8 7.2 6.7 3.5 4.4 10.8 6.4 4.8 5.3 7.4 5.7 3.6 6.3 6.0 5.6 3.2 6.8 5.3 7.0 9.5 14.9 8.7 10.3 23.7 4.6 5.4 16.4 5.3 5.3 7.3 10.0 17.7 6.6 16.1 13.3 4.6 4.1 13.6 18.8 15.0 9.2 8.4 32.4 43.2 29.2 15.7 6.1 26.0 25.6 7.2 11.2 7.2 16.3 6.1 5.4 17.4 16.9 27.7 5.4 11.8 17.9 68.2 27.1 5.2 13.9 10.9 13.0 11.8 8.0 72.3 19.6 10.2 7.6 10.6 6.2 20.7 7.8 8.2 6.1 21.7 12.0 7.6 12.1 26.6 17.6 18.4 6.0 14.4 9.1 1.6 1.5 0.9 2.1 1.9 2.8 1.5 2.0 1.9 1.6 2.3 2.3 2.6 1.2 3.1 2.0 2.0 2.0 0.9 5.5 5.9 8.8 6.4 5.7 6.7 6.0 5.1 6.3 5.3 6.3 9.5 16.0 6.4 10.5 3.9 14.7 22.6 36.9 15.6 10.8 7.3 12.7 11.7 11.2 5.7 15.7 9.2 12.5 12.3 25.8 5.6 7.9 11.4 1.5 12.3 16.9 11.8 13.7 11.6 6.2 5.3 11.3 11.7 11.7 18.3 15.2 16.7 10.8 9.9 5.3 6.7 5.3 10.2 8.2 10.4 13.8 0.6 6.2 9.7 8.8 1.0 6.9 3.1 12.3 7.5 6.7 11.4 5.6 8.2 12.6 26.2 4.1 5.3 11.0 7.8 6.6 17.0 10.3 11.0 12.5 21.3 31.7 10.5 14.5 11.9 14.6 35.9 ZNF143 "pHZ-1, SBF, STAF" ENSG00000166478 "Zinc finger protein 143" P52747 11 9460319-9528524 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003263, HPA003264, HPA074818" Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus, Vesicles" "HPA003263: AB_1080672, HPA003264: , HPA074818: AB_2686715" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (5.51e-2)" "unprognostic (9.72e-2)" "unprognostic (5.09e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.76e-5)" "unprognostic (4.87e-3)" "unprognostic (2.57e-3)" "unprognostic (9.56e-2)" "unprognostic (1.26e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.20e-3)" "unprognostic (1.92e-2)" "unprognostic (1.06e-2)" "unprognostic (7.55e-2)" 9.0 6.1 8.6 11.4 10.1 18.6 9.6 17.3 9.9 10.0 10.8 9.7 9.5 10.5 14.4 9.8 10.1 8.4 9.3 7.9 9.3 8.6 9.6 9.1 15.7 9.9 8.8 13.7 7.7 7.9 7.1 10.4 11.2 8.7 9.9 16.1 8.9 8.0 17.3 10.2 8.2 9.5 9.8 11.1 7.7 16.9 9.0 18.9 14.6 11.5 14.1 11.2 8.4 14.9 20.0 18.8 23.4 15.2 18.9 17.4 21.5 21.8 17.3 16.4 17.9 26.7 24.3 19.6 9.7 17.7 14.0 22.5 23.1 17.3 24.5 20.0 27.7 18.5 27.7 18.7 15.6 25.9 17.8 15.3 20.4 22.2 19.4 21.4 16.3 17.9 20.5 23.3 18.3 17.1 24.1 10.6 26.3 23.0 19.9 21.4 21.2 12.3 14.7 24.0 16.1 15.8 24.0 16.0 14.3 20.6 14.9 14.6 15.6 21.4 15.3 15.1 19.6 11.5 21.6 33.4 13.8 14.8 12.5 39.1 24.6 57.3 28.0 24.9 25.0 23.0 24.6 22.9 20.9 18.2 22.8 19.6 45.1 19.4 28.2 10.1 29.7 19.6 8.6 10.1 17.3 9.9 7.9 9.3 9.9 8.8 11.2 9.8 9.0 14.9 17.9 6.4 12.1 6.2 14.7 26.6 34.1 12.1 17.6 9.3 8.7 13.2 15.5 7.2 10.3 5.5 8.4 10.0 17.1 10.1 3.9 12.5 20.3 18.7 14.9 13.0 6.6 25.4 8.1 11.5 16.2 14.5 9.7 16.3 14.0 7.7 6.8 7.6 9.9 5.0 7.4 6.9 14.2 8.3 22.0 10.0 11.8 15.8 10.6 12.2 16.3 15.5 17.5 7.5 9.8 14.1 7.7 6.8 15.4 20.1 6.3 7.7 15.0 14.3 59.2 18.3 16.7 50.5 21.3 12.8 23.4 18.3 18.1 7.3 7.9 26.9 ZNF169 MGC51961 ENSG00000175787 "Zinc finger protein 169" Q14929 9 94259298-94301829 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.4;Inhibitory neurons: 16.7;NK-cells: 15.5;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041769, HPA061185" Uncertain Approved "Nucleoplasm,Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Vesicles, Cytosol" "HPA041769: AB_2677662, HPA061185: " "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (3.27e-2)" "unprognostic (9.08e-3)" "unprognostic (1.18e-3)" "unprognostic (7.33e-2)" "unprognostic (2.27e-1)" "unprognostic (7.45e-2)" "unprognostic (6.79e-2)" "unprognostic (1.69e-2)" "unprognostic (1.49e-4)" "unprognostic (6.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (2.15e-4)" 3.0 2.7 3.8 4.4 4.4 3.2 3.9 4.3 4.8 5.4 3.4 4.3 2.9 3.9 4.2 2.6 4.8 1.7 2.6 3.8 2.4 3.7 2.1 3.2 6.0 3.7 2.6 5.4 3.3 2.3 2.7 2.1 3.8 4.2 5.5 4.2 3.9 2.6 4.6 5.2 5.7 2.8 1.8 6.1 4.1 2.6 3.5 3.8 4.8 1.8 5.1 4.0 4.1 5.7 3.0 2.6 2.8 4.9 1.5 3.4 3.1 1.1 2.0 2.2 2.3 1.8 4.3 7.3 1.4 1.7 2.2 5.8 5.7 2.7 2.9 4.0 6.3 5.1 6.5 3.3 1.8 7.8 5.0 3.0 2.9 1.8 2.8 2.8 2.7 6.8 4.6 2.1 2.8 2.9 3.7 4.4 4.6 6.2 3.2 3.1 2.0 2.3 1.9 2.5 2.9 3.5 1.9 3.5 1.4 2.7 2.2 3.2 3.1 2.0 2.6 2.6 2.2 3.9 1.5 1.4 1.9 5.2 1.9 2.2 3.0 3.2 2.4 3.4 3.1 3.0 2.9 1.7 2.1 4.0 3.0 4.1 2.5 3.3 2.6 2.0 3.1 1.7 3.8 4.4 4.3 4.8 3.8 2.4 3.7 2.6 3.8 1.8 3.5 5.7 2.0 3.2 0.5 10.4 8.0 0.3 2.2 1.3 1.2 4.8 1.0 1.3 1.2 1.5 2.6 1.8 4.2 0.5 3.9 2.5 0.0 1.1 1.0 0.6 1.4 2.3 1.2 3.8 18.4 0.9 0.8 1.8 2.6 0.5 0.0 6.3 2.5 0.8 0.7 5.0 16.7 4.1 0.0 4.4 1.6 1.0 5.9 4.1 0.0 7.5 7.8 2.3 15.5 14.1 19.9 1.2 3.1 3.4 2.6 2.6 4.3 1.0 2.4 4.5 0.0 2.9 1.7 5.2 3.6 0.7 0.4 0.4 4.7 3.7 2.1 2.4 ZNF18 "HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38" ENSG00000154957 "Zinc finger protein 18" P17022 17 11977439-11997475 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.0;Late spermatids: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006144 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA006144: AB_1080683" "unprognostic (2.99e-3)" "prognostic favorable (6.32e-4)" "unprognostic (2.32e-1)" "unprognostic (2.50e-2)" "unprognostic (4.91e-2)" "unprognostic (2.72e-3)" "unprognostic (2.28e-2)" "unprognostic (5.93e-3)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "prognostic favorable (5.12e-6)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (1.52e-2)" "unprognostic (9.31e-2)" "unprognostic (3.34e-2)" "unprognostic (3.53e-3)" 7.2 5.7 7.9 5.8 8.6 13.7 6.1 7.7 11.2 6.7 7.4 6.0 5.0 5.3 6.3 7.5 5.7 5.5 5.9 7.9 8.3 5.8 12.4 5.1 8.8 8.4 8.0 5.7 6.0 4.3 7.7 4.0 8.8 8.4 6.7 4.9 5.2 5.1 7.3 9.7 6.6 5.8 7.6 10.2 5.3 14.1 8.1 8.5 6.2 4.6 8.0 6.3 6.6 9.8 3.0 6.1 6.4 9.7 11.9 10.5 3.4 4.3 7.5 5.5 5.9 2.9 5.0 10.3 6.3 4.7 4.8 6.1 5.4 6.8 5.9 7.8 4.5 6.1 6.9 4.0 8.4 3.4 7.8 8.7 10.8 4.2 7.6 6.3 8.4 12.0 3.6 4.7 7.6 3.1 11.5 6.9 4.8 10.9 2.8 9.4 6.5 4.6 8.0 3.6 2.5 5.4 7.3 3.6 5.9 37.2 5.1 3.2 6.7 6.5 3.2 2.9 3.3 5.2 4.1 5.1 7.5 7.9 7.8 10.5 5.9 6.9 10.3 5.9 9.6 9.0 9.3 9.7 5.8 7.2 10.0 10.3 19.1 7.7 8.2 8.6 11.1 6.1 7.9 8.6 7.7 11.2 7.9 8.3 8.4 8.0 8.8 7.6 8.1 9.8 2.5 0.0 2.0 10.1 3.8 2.0 1.7 4.2 4.6 2.0 2.0 1.4 1.6 2.8 2.1 1.8 2.1 2.4 3.5 2.5 1.9 3.1 23.0 1.8 2.8 1.9 1.2 5.2 7.4 0.9 2.2 2.7 2.0 1.8 2.5 5.1 2.5 3.7 4.3 1.7 8.4 4.2 6.1 3.8 1.8 27.3 3.4 3.2 1.8 8.4 3.4 2.0 5.2 7.5 9.3 2.1 5.0 3.4 2.3 1.6 3.9 3.1 2.5 1.2 0.0 2.5 2.3 9.6 4.9 5.0 2.3 1.5 4.7 2.8 3.1 1.1 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF2 "A1-5, Zfp661, ZNF661" ENSG00000275111 "Zinc finger protein 2" Q9BSG1 2 95165432-95184317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041358 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA041358: AB_10795539" "unprognostic (1.18e-1)" "unprognostic (6.41e-3)" "unprognostic (5.81e-2)" "unprognostic (9.29e-2)" "unprognostic (4.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.13e-3)" "prognostic favorable (4.69e-5)" "unprognostic (1.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.37e-2)" "unprognostic (2.63e-2)" "unprognostic (2.66e-3)" "unprognostic (2.57e-2)" "unprognostic (6.78e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" 2.1 2.6 2.3 2.3 2.5 0.7 2.5 2.7 2.9 3.2 2.0 2.4 2.1 2.4 3.2 2.3 2.9 1.5 3.1 2.2 2.2 2.7 1.9 2.4 3.1 2.3 2.3 3.9 2.1 3.8 1.9 2.2 2.4 2.6 1.7 3.0 2.3 3.2 3.4 2.9 1.8 2.6 2.1 2.9 2.5 3.0 2.3 3.2 3.1 3.6 3.2 2.3 1.8 3.0 4.1 3.7 4.5 7.6 6.2 5.1 2.8 4.0 5.7 6.1 7.7 3.9 2.5 2.2 3.0 4.1 4.3 3.0 5.1 3.2 6.1 5.8 4.0 5.8 2.9 4.9 5.1 2.8 3.4 4.4 4.3 5.5 7.8 6.3 5.1 4.6 3.9 1.9 5.9 3.1 4.2 4.1 1.8 3.3 4.9 4.1 7.4 3.3 3.4 2.3 4.0 5.2 4.1 5.7 4.9 3.8 3.6 4.4 4.0 7.0 4.2 5.4 3.6 3.4 3.3 3.0 4.4 3.7 5.2 5.6 3.4 12.9 6.3 4.8 4.4 5.4 4.9 5.5 4.0 5.1 6.3 6.2 2.6 3.5 4.0 3.1 6.2 4.0 2.3 2.5 2.7 2.9 2.2 2.2 2.3 2.3 2.4 2.1 2.3 3.0 2.1 0.0 1.7 3.3 2.0 1.0 0.7 1.1 1.8 3.3 2.3 1.5 2.6 5.7 2.1 1.8 0.0 1.8 2.9 0.8 5.9 1.8 2.7 1.3 2.0 1.9 0.0 1.3 7.7 2.0 1.4 2.1 1.5 1.2 1.3 4.7 2.5 1.6 2.5 1.7 6.2 0.7 0.0 2.5 1.2 0.8 2.1 2.2 0.0 3.7 0.5 4.2 4.1 7.1 5.7 0.9 0.5 3.0 1.4 0.9 1.5 2.8 2.5 2.7 6.6 1.6 2.0 5.5 7.5 0.9 1.1 1.6 1.6 2.8 1.1 0.7 ZNF202 "ZKSCAN10, ZSCAN42" ENSG00000166261 "Zinc finger protein 202" O95125 11 123723914-123741675 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 14.7;Spermatogonia: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059229 Approved "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Nuclear bodies" "HPA059229: " "unprognostic (3.12e-2)" "unprognostic (7.75e-2)" "unprognostic (2.20e-2)" "unprognostic (4.49e-2)" "unprognostic (2.10e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.23e-1)" "unprognostic (1.74e-3)" "unprognostic (2.80e-1)" "unprognostic (9.48e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (9.93e-7)" "unprognostic (2.61e-2)" "unprognostic (2.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" 5.7 4.7 5.9 6.7 5.9 5.2 7.6 5.9 6.5 8.1 5.7 6.3 4.4 9.7 9.3 6.0 6.8 4.6 4.5 5.7 5.9 6.2 5.1 5.1 8.9 5.4 5.8 10.4 9.7 5.2 5.9 6.2 5.4 7.2 7.9 6.1 6.0 5.3 6.2 8.4 6.5 7.3 4.8 9.9 6.2 9.8 5.8 6.7 6.9 3.9 8.7 6.9 6.4 6.8 6.0 9.3 15.3 18.5 6.6 10.1 11.9 9.3 7.4 8.5 7.6 10.5 15.7 17.7 8.6 7.2 13.7 14.3 15.9 10.6 11.7 7.3 8.9 31.5 6.6 10.2 9.0 18.5 8.9 7.2 21.0 9.7 28.7 7.3 10.0 14.8 17.1 11.8 11.2 6.3 16.0 25.3 25.2 21.0 12.8 19.2 9.5 6.5 8.3 11.4 11.3 12.6 7.8 9.4 6.2 12.5 17.8 12.8 8.7 16.3 10.5 11.8 9.5 7.6 5.9 12.1 4.3 20.2 10.8 0.0 1.2 0.0 1.7 1.8 1.6 1.6 2.3 2.5 1.9 1.9 2.6 2.4 0.0 1.6 0.7 1.2 2.2 1.7 5.9 5.9 5.9 6.5 5.7 5.9 5.4 5.8 5.4 4.8 5.8 6.8 3.1 6.4 0.5 7.8 3.8 2.9 3.8 1.9 0.6 3.1 3.4 3.2 3.1 2.8 9.7 3.7 0.0 2.2 2.1 1.5 1.9 2.2 5.1 1.4 3.3 3.1 3.0 1.7 8.9 3.5 1.7 2.8 4.6 2.0 3.8 6.0 2.2 1.9 1.8 6.7 8.3 3.9 0.0 2.0 2.0 5.0 1.8 3.1 0.0 3.7 1.6 2.4 1.0 6.6 11.0 3.2 2.4 1.2 3.6 2.5 1.0 1.4 1.3 3.1 6.6 5.0 2.2 14.7 14.5 3.6 3.0 0.8 3.0 3.1 3.2 2.9 ZNF213 "CR53, ZKSCAN21, ZSCAN53" ENSG00000085644 "Zinc finger protein 213" O14771 16 3129777-3142804 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.7;Late spermatids: 58.3;Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035000, HPA056750" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA035000: AB_10669997, HPA056750: AB_2683225" "unprognostic (1.94e-1)" "unprognostic (1.62e-2)" "unprognostic (3.25e-1)" "unprognostic (1.87e-2)" "unprognostic (1.31e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (6.74e-4)" "unprognostic (4.72e-2)" "unprognostic (1.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-1)" "unprognostic (4.73e-1)" "unprognostic (7.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.57e-1)" 4.3 6.7 5.0 3.6 4.9 3.9 4.6 5.7 6.2 5.1 0.9 5.7 5.5 6.5 1.7 6.9 5.1 3.2 5.6 4.9 3.3 4.6 2.5 3.5 5.7 7.1 4.6 6.5 7.2 4.9 6.7 2.1 4.7 5.7 1.2 4.3 10.4 3.0 11.5 10.0 6.8 2.3 3.4 4.9 5.7 17.9 5.1 2.5 5.2 1.2 0.9 5.7 5.2 5.4 3.6 11.1 4.9 11.3 4.7 3.8 6.0 6.4 2.6 3.3 3.9 3.6 7.2 4.3 6.2 4.2 4.9 8.4 2.2 7.1 1.3 9.2 8.3 2.4 13.4 7.0 8.8 7.5 7.8 3.7 8.7 4.4 1.8 2.5 2.5 8.2 8.0 9.4 2.2 15.1 7.0 9.1 8.3 3.8 8.4 9.4 5.7 8.1 2.6 2.4 10.0 8.5 9.7 5.7 4.7 3.1 7.5 12.8 6.3 6.8 6.2 7.7 4.5 5.2 5.4 6.4 2.7 9.9 5.3 0.0 0.5 1.3 1.2 0.9 1.1 0.9 1.2 0.8 0.5 1.5 1.5 1.1 1.3 1.6 0.7 1.2 0.7 0.8 5.0 4.9 5.7 6.2 4.9 3.3 7.1 4.6 4.7 3.4 5.1 5.4 4.1 0.0 1.1 3.6 1.9 1.9 1.5 2.1 2.8 5.3 4.8 4.2 4.4 1.5 1.7 0.0 2.1 1.8 3.4 10.2 1.9 4.0 22.7 3.0 3.1 3.4 2.4 2.1 3.2 4.9 2.0 3.9 4.6 4.4 4.5 4.8 4.6 1.4 3.2 8.4 3.5 6.0 0.0 5.1 1.7 58.3 6.5 3.6 0.0 1.0 4.4 5.6 5.2 0.5 4.6 5.2 4.2 7.2 1.3 2.1 14.6 2.5 1.5 5.2 19.7 3.9 4.1 9.5 4.5 4.8 2.0 1.4 2.3 3.5 6.6 1.8 ZNF232 ZSCAN11 ENSG00000167840 "Zinc finger protein 232" Q9UNY5 17 5105541-5123116 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 18.1;Spermatogonia: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027309, HPA028611" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA027309: AB_10603464, HPA028611: AB_2672700" "unprognostic (4.20e-2)" "unprognostic (2.06e-3)" "unprognostic (3.69e-1)" "unprognostic (5.59e-3)" "unprognostic (5.21e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (3.12e-2)" "unprognostic (5.46e-3)" "unprognostic (2.49e-2)" "prognostic favorable (6.55e-4)" "unprognostic (3.28e-2)" "unprognostic (3.49e-3)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (1.11e-1)" "unprognostic (8.61e-3)" 1.8 1.2 3.0 1.1 3.5 0.4 1.9 3.4 4.3 2.7 3.1 2.7 1.0 2.4 2.4 1.6 2.3 1.3 2.0 3.1 3.5 2.3 2.1 1.5 1.9 3.6 3.1 3.4 2.8 1.9 1.6 1.5 3.5 2.1 1.3 2.3 1.9 1.3 2.0 1.4 1.8 1.9 3.1 1.9 2.2 2.6 3.5 1.6 2.4 1.8 1.4 1.8 1.8 4.2 5.8 4.3 6.9 7.0 2.4 1.0 3.7 2.8 1.4 2.7 3.7 6.7 1.4 11.5 3.4 1.0 4.0 3.9 4.9 2.8 1.6 4.6 7.4 2.0 10.0 6.0 3.5 0.0 3.4 1.9 3.0 2.9 2.5 1.9 2.0 13.7 10.0 4.1 3.3 2.8 10.1 4.0 13.5 4.9 4.6 8.5 4.4 7.8 2.2 0.8 7.2 4.7 5.4 2.1 4.6 5.2 1.1 2.8 3.2 2.7 4.6 2.1 5.5 5.5 9.3 3.0 6.9 0.3 4.6 1.3 1.9 1.9 4.2 2.0 5.2 12.5 4.7 5.8 3.9 11.4 7.0 6.5 0.1 5.7 1.2 7.4 4.3 3.5 3.0 3.5 3.4 4.3 3.1 3.5 3.6 3.1 3.5 3.1 3.5 4.2 4.2 0.0 2.6 2.0 5.2 4.2 2.9 4.0 5.7 5.7 3.8 6.6 5.6 0.0 3.9 5.5 0.0 3.9 3.5 3.1 3.9 7.0 8.6 5.5 6.8 5.2 1.2 2.1 3.4 4.0 5.0 3.4 1.5 2.2 0.0 4.0 3.6 3.9 6.1 0.0 3.3 2.4 0.0 3.8 1.3 6.9 3.7 2.9 0.0 3.7 1.8 4.2 0.0 3.0 8.1 3.7 7.6 5.3 1.4 4.1 2.6 3.2 6.5 3.9 0.0 4.4 4.4 18.1 21.7 3.3 4.7 2.1 3.2 3.4 3.8 1.8 ZNF236 ENSG00000130856 "Zinc finger protein 236" Q9UL36 18 76822557-76972901 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008600 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cell Junctions" Cytosol "HPA008600: AB_1080696" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "unprognostic (3.13e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (9.88e-3)" "unprognostic (5.51e-2)" "unprognostic (1.77e-1)" "unprognostic (2.83e-3)" "unprognostic (2.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "unprognostic (2.95e-2)" "unprognostic (9.40e-2)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" 2.5 2.2 3.2 2.2 5.3 4.9 2.4 9.2 4.4 3.0 0.0 2.8 1.9 3.2 2.8 2.5 2.9 2.0 2.3 3.4 4.3 2.0 2.1 2.1 2.6 2.3 3.5 4.3 2.8 3.1 3.6 2.2 2.6 2.6 1.5 2.4 2.7 2.3 2.5 4.1 2.5 2.1 1.4 2.3 2.8 6.8 3.5 4.1 2.6 3.1 2.4 2.6 2.9 5.7 2.5 2.4 4.7 3.4 3.7 3.4 1.9 1.8 2.6 2.9 2.4 2.3 2.3 3.6 0.9 2.5 3.2 4.6 3.0 2.8 2.5 3.8 3.1 3.4 3.9 2.8 2.1 5.7 3.7 3.4 3.1 2.8 4.4 3.4 3.0 5.5 3.3 2.9 3.1 2.2 6.9 3.2 2.5 0.6 2.6 4.3 4.9 2.4 2.4 3.8 2.6 2.8 3.6 2.2 2.5 2.2 2.5 3.9 3.2 5.3 2.0 1.3 2.9 2.0 3.0 4.4 3.6 3.0 3.9 0.7 2.0 3.9 3.1 1.9 3.0 5.9 2.3 2.1 1.4 4.4 2.6 2.7 2.1 1.9 1.8 2.8 2.7 0.9 3.2 5.3 9.2 4.4 3.4 4.3 2.3 3.5 2.6 1.4 3.5 5.7 9.3 9.6 7.9 39.5 11.9 7.1 8.5 5.4 10.8 15.3 8.0 7.6 9.5 12.8 6.7 7.3 10.4 8.4 12.9 5.6 1.9 5.4 6.9 10.8 12.6 9.3 6.0 12.8 37.7 3.9 7.2 8.8 9.2 10.5 1.3 15.8 10.0 6.8 6.0 25.2 25.3 5.0 6.1 7.2 7.2 6.0 10.5 8.7 7.2 16.9 8.4 9.7 9.2 41.7 39.7 4.7 3.1 7.2 9.1 6.8 5.9 3.0 10.9 15.9 6.6 14.2 10.4 26.7 26.2 8.8 8.4 6.0 12.4 7.8 5.7 6.3 ZNF263 "FPM315, ZKSCAN12, ZSCAN44" ENSG00000006194 "Zinc finger protein 263" O14978 16 3263800-3301401 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035085, HPA035086" Approved Supported "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "Nucleoplasm, Mitotic spindle" "HPA035085: AB_10671099, HPA035086: AB_10603244" "unprognostic (2.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (3.33e-1)" "unprognostic (2.25e-1)" "unprognostic (6.42e-2)" "unprognostic (7.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (6.39e-2)" "unprognostic (2.30e-3)" "unprognostic (2.98e-3)" "unprognostic (5.10e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (2.66e-1)" 20.8 18.3 18.3 16.8 18.1 19.1 24.1 20.4 22.5 20.2 20.3 20.1 14.5 22.9 23.2 15.4 24.5 16.7 15.1 19.1 17.7 20.4 17.6 19.4 22.6 20.1 17.6 29.2 21.5 30.7 23.4 20.4 17.2 21.4 17.0 24.6 20.2 20.2 17.3 24.0 19.3 18.7 16.6 23.2 22.0 18.1 18.2 22.3 20.0 13.7 21.5 19.5 17.5 20.5 19.7 25.1 27.6 40.8 22.7 28.8 36.6 26.1 38.6 30.0 32.2 27.5 30.3 74.2 26.5 33.6 28.6 25.7 38.6 26.4 29.9 41.6 41.3 31.4 35.6 25.6 25.7 48.8 38.5 34.0 53.3 27.6 40.0 33.5 26.2 44.5 37.9 47.4 24.8 25.5 43.9 37.2 55.7 23.2 19.2 70.4 29.8 57.6 20.7 18.4 40.6 43.8 27.9 30.0 30.9 32.5 32.8 57.7 30.1 31.4 30.9 23.3 25.4 50.8 60.8 88.0 12.9 23.6 23.8 1.4 2.5 6.4 3.5 2.4 4.0 2.5 4.2 4.7 3.5 4.4 5.4 3.8 3.0 4.5 3.4 2.9 3.1 1.9 18.3 18.1 20.4 22.5 19.1 17.7 20.1 17.6 17.2 16.6 18.2 20.5 15.9 0.0 11.5 8.8 16.6 17.5 17.1 3.7 16.5 12.5 13.9 12.8 4.6 15.7 5.0 1.8 0.0 11.5 16.1 8.7 7.9 10.2 60.9 10.5 8.8 12.8 13.2 6.3 7.9 10.0 11.1 11.9 11.2 13.5 7.0 14.3 10.0 7.1 9.1 3.3 6.7 12.1 10.2 9.4 14.3 35.1 8.1 9.5 16.0 7.5 8.4 9.8 19.6 8.0 7.8 10.3 6.0 7.9 11.8 16.3 7.5 6.3 5.7 9.0 13.1 17.5 17.3 13.0 11.1 14.3 20.6 11.1 15.0 15.2 12.3 13.6 ZNF266 HZF1 ENSG00000174652 "Zinc finger protein 266" Q14584 19 9412461-9435571 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 74.2" "Low region specificity" "Detected in all" "HPA026836, HPA054110" Uncertain Supported "Nucleoplasm,Vesicles,Rods & Rings" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Rods & Rings" "HPA026836: AB_2672018, HPA054110: AB_2682383" "unprognostic (2.50e-2)" "prognostic favorable (1.41e-4)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "unprognostic (7.60e-2)" "prognostic favorable (3.94e-6)" "unprognostic (1.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (4.59e-2)" "unprognostic (9.00e-3)" "prognostic favorable (3.03e-5)" "unprognostic (2.92e-3)" "prognostic unfavorable (1.82e-4)" "unprognostic (7.76e-2)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" "prognostic favorable (9.15e-5)" 21.0 17.6 8.7 12.7 9.1 17.5 22.8 10.5 10.7 26.3 10.1 22.8 10.2 20.6 53.3 17.5 21.7 9.7 15.3 8.4 8.9 16.3 15.4 21.8 23.8 8.9 8.9 24.2 15.1 15.7 20.1 15.0 9.0 31.5 15.9 12.6 19.0 14.6 11.4 25.1 29.4 14.0 8.8 44.1 19.4 16.7 9.1 27.6 26.3 8.6 27.9 20.0 20.3 9.9 21.5 5.4 13.0 26.6 10.8 15.3 10.3 19.4 18.9 19.1 27.5 10.1 7.1 22.5 12.6 10.7 7.4 6.3 19.3 10.8 22.1 6.8 29.6 27.1 21.8 13.9 9.2 16.9 17.3 16.4 16.0 9.6 14.3 15.5 14.2 25.7 18.0 0.0 16.7 2.1 25.8 74.2 16.6 9.9 16.5 9.6 16.4 16.9 13.6 22.2 13.0 19.5 10.5 11.0 14.0 14.0 8.8 14.2 13.7 16.6 6.9 23.1 11.8 32.1 55.6 28.0 4.5 14.8 11.3 4.0 3.5 4.9 9.6 4.1 6.8 4.8 5.7 7.4 2.9 5.3 7.5 8.1 2.0 11.1 5.4 2.7 7.5 4.8 8.7 9.1 10.5 10.7 8.4 8.9 8.9 8.9 9.0 8.8 9.1 9.9 8.8 0.0 14.3 10.4 15.3 4.0 5.9 5.3 11.4 8.0 9.0 8.8 5.5 4.3 8.7 3.7 12.5 4.8 22.4 7.2 3.9 5.5 0.7 5.0 5.4 7.5 9.5 14.3 12.5 3.7 3.3 6.6 11.2 6.5 12.0 12.9 10.8 3.1 4.8 8.4 12.0 7.1 6.1 11.4 7.2 1.4 6.2 9.1 5.4 14.0 11.3 4.2 20.6 14.1 15.1 4.7 5.2 4.5 10.5 5.6 7.6 1.4 6.6 9.5 6.6 7.2 6.2 5.5 8.7 6.4 4.7 4.7 17.1 6.5 7.4 6.4 ZNF276 "CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477" ENSG00000158805 "Zinc finger protein 276" Q8N554 16 89720400-89740925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 63.5;NK-cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021309, HPA022255" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA021309: AB_1859024, HPA022255: AB_1859025" "unprognostic (1.45e-2)" "unprognostic (7.05e-2)" "unprognostic (1.17e-2)" "unprognostic (8.25e-3)" "unprognostic (1.17e-1)" "unprognostic (2.95e-3)" "unprognostic (1.27e-1)" "unprognostic (3.70e-2)" "unprognostic (1.92e-1)" "unprognostic (7.85e-2)" "unprognostic (1.59e-2)" "unprognostic (1.36e-3)" "prognostic unfavorable (3.37e-4)" "unprognostic (2.65e-2)" "unprognostic (4.14e-1)" "unprognostic (1.26e-1)" "unprognostic (1.62e-3)" 9.9 12.5 13.3 11.0 14.2 21.0 10.4 13.5 15.9 12.5 9.3 13.0 10.7 10.0 3.5 19.1 14.5 5.3 10.0 12.4 11.8 13.5 14.3 12.0 16.9 15.2 13.2 16.0 13.6 4.4 14.6 4.8 14.0 13.4 5.7 3.8 11.7 4.2 10.6 17.6 19.6 4.5 11.0 26.8 12.0 9.3 14.4 8.1 12.8 4.6 10.6 10.8 14.4 19.7 6.6 5.5 4.8 11.8 3.7 5.4 7.9 5.2 3.0 4.6 1.7 7.4 7.4 8.4 4.6 5.2 2.1 12.1 6.0 5.6 3.1 5.4 25.8 7.9 12.0 3.1 6.8 7.7 9.7 7.3 7.2 6.2 4.7 4.5 5.9 7.7 13.9 7.8 1.9 9.9 9.1 19.3 3.2 7.1 10.6 14.4 5.5 6.0 5.5 3.9 11.5 10.0 9.4 8.8 6.0 2.8 11.8 11.0 7.6 6.3 9.1 5.2 4.3 24.4 8.5 4.7 6.2 14.5 7.2 3.8 1.2 1.5 6.6 1.1 3.3 1.2 3.7 5.4 0.7 1.7 3.7 4.9 3.1 3.8 1.0 1.2 2.7 2.0 13.3 14.2 13.5 15.9 12.4 11.8 15.2 13.2 14.0 11.0 14.4 19.7 17.1 9.6 13.3 15.7 20.8 11.5 8.3 11.2 14.8 15.8 13.9 11.7 2.6 12.8 10.7 11.0 20.9 4.6 63.5 16.8 1.9 7.6 1.9 11.5 14.7 13.6 7.2 13.5 17.6 6.6 3.9 9.5 15.8 14.4 12.6 14.3 20.0 11.5 9.0 6.7 14.6 14.5 2.0 9.8 9.8 2.3 11.5 19.7 8.8 18.7 13.5 9.7 89.6 25.1 30.6 9.2 13.2 10.5 25.4 12.9 19.8 3.4 10.1 21.6 13.1 12.3 8.7 17.0 9.7 15.5 16.1 4.0 39.0 24.0 15.7 11.0 ZNF280D "FLJ20086, SUHW4, ZNF634" ENSG00000137871 "Zinc finger protein 280D" Q6N043 15 56630176-56734086 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 176.6;Oligodendrocyte precursor cells: 200.1;Oligodendrocytes: 293.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA030233 Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Golgi apparatus, Centrosome" "HPA030233: AB_10602590" "unprognostic (1.57e-1)" "unprognostic (2.17e-1)" "unprognostic (3.55e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.70e-2)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.15e-2)" "unprognostic (3.63e-1)" "unprognostic (7.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-2)" "unprognostic (1.98e-1)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "unprognostic (7.72e-2)" 11.3 11.4 3.4 8.7 3.9 23.1 15.4 9.0 4.6 18.0 4.8 10.2 7.5 20.1 8.1 8.4 12.4 9.6 9.2 3.6 3.8 10.3 13.2 10.1 10.0 3.1 3.0 23.7 13.7 11.1 4.5 11.5 3.6 10.6 11.5 12.4 10.5 9.9 12.6 6.6 9.5 15.1 4.0 10.3 10.3 7.8 3.5 35.9 11.5 11.6 9.9 10.9 8.5 9.8 13.4 7.4 13.6 20.9 13.3 18.7 9.9 20.2 14.3 8.2 9.3 5.4 13.6 22.7 8.4 14.5 7.9 10.0 6.7 5.3 9.9 11.6 4.1 2.4 12.5 8.2 13.3 20.4 6.6 12.8 7.6 5.6 8.0 20.6 18.3 23.0 11.9 25.7 13.0 9.6 14.4 2.3 0.0 15.6 5.8 4.3 22.2 16.1 10.1 15.4 11.2 20.0 16.9 10.5 6.7 0.7 11.4 19.9 16.2 12.1 18.2 11.3 16.1 13.2 21.6 0.0 13.7 31.0 13.2 7.8 2.6 3.5 2.1 2.2 2.0 3.4 1.9 1.7 3.6 3.2 2.0 2.4 0.4 1.8 2.0 3.6 1.9 1.0 3.4 3.9 9.0 4.6 3.6 3.8 3.1 3.0 3.6 4.0 3.5 9.8 32.4 9.6 18.9 176.6 31.1 11.1 18.3 12.9 42.7 79.8 20.5 20.7 37.9 22.8 14.6 3.7 83.4 23.0 25.5 12.2 7.9 12.0 18.3 14.3 33.0 36.5 32.3 27.5 107.2 14.0 21.5 37.5 26.0 14.2 17.7 37.8 34.2 31.1 36.6 69.0 151.3 25.7 16.2 35.6 18.1 49.5 33.2 22.9 16.0 91.8 27.0 24.9 28.8 200.1 293.3 10.5 10.4 21.1 41.4 21.1 26.8 14.2 12.8 84.5 6.6 47.4 30.8 49.4 33.8 26.8 13.9 13.3 21.4 27.7 22.2 16.3 ZNF300 ENSG00000145908 "Zinc finger protein 300" Q96RE9 5 150894392-150904983 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 13.3;Granulosa cells: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 36.1" "Low region specificity" "Detected in all" "HPA028975, HPA051777" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Nuclear bodies" "HPA028975: AB_2672851, HPA051777: AB_2681606" "unprognostic (5.06e-2)" "unprognostic (1.05e-2)" "unprognostic (8.41e-2)" "unprognostic (2.31e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (1.15e-1)" "unprognostic (6.23e-3)" "unprognostic (4.21e-2)" "unprognostic (3.23e-1)" "unprognostic (8.62e-2)" "unprognostic (6.85e-3)" "prognostic unfavorable (3.21e-6)" "unprognostic (3.62e-3)" "unprognostic (2.99e-1)" "unprognostic (3.46e-1)" "unprognostic (1.50e-2)" 3.6 1.0 2.3 2.6 3.2 2.7 4.5 3.8 2.8 6.5 2.3 3.6 2.7 7.4 2.3 5.1 4.4 3.3 3.2 2.3 2.9 7.4 1.2 2.4 3.0 3.0 3.1 10.2 5.5 0.8 2.4 1.5 3.1 5.4 2.7 9.1 2.8 2.3 0.9 4.4 3.8 4.0 2.6 3.9 4.7 6.4 2.9 2.8 6.9 1.5 2.9 4.5 4.9 3.5 2.1 4.7 28.2 0.0 2.4 5.8 0.0 7.1 5.6 6.1 8.7 2.4 3.5 0.0 6.1 5.9 18.3 4.2 0.0 16.2 9.5 0.0 9.3 0.0 36.1 3.9 5.0 0.2 0.1 8.9 5.0 12.7 14.7 8.6 10.4 0.1 0.0 15.1 6.1 0.0 0.0 1.5 27.2 0.0 0.0 0.0 4.1 8.5 4.4 5.3 15.9 26.2 16.7 14.3 9.8 17.1 9.4 0.0 4.6 8.1 3.4 5.9 12.9 0.5 0.2 0.0 0.8 0.1 17.1 0.0 0.1 0.3 0.1 0.4 0.0 0.2 0.2 0.0 0.3 1.3 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 2.3 3.2 3.8 2.8 2.3 2.9 3.0 3.1 3.1 2.6 2.9 3.5 2.0 0.0 0.5 0.3 1.8 1.5 3.1 2.3 7.4 4.0 2.3 1.7 0.6 1.5 2.7 7.3 0.0 0.7 1.9 0.3 1.9 2.5 3.2 1.8 5.3 2.3 3.0 4.0 0.8 1.6 2.2 3.8 13.3 1.9 0.0 11.5 1.8 0.2 0.5 0.0 1.9 1.4 2.0 1.0 1.2 0.9 2.5 0.8 0.0 5.6 1.5 3.3 3.1 5.5 6.7 1.8 0.1 1.2 0.3 2.0 0.6 1.8 0.8 4.3 6.6 4.1 2.8 7.2 3.7 5.9 2.3 0.8 1.2 2.7 1.8 3.0 ZNF322 "bA457M11.2, bA457M11.3, HCG12, ZNF322A, ZNF388, ZNF489" ENSG00000181315 "Zinc finger protein 322" Q6U7Q0 6 26634383-26659752 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043161, HPA046692" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA043161: AB_2678346, HPA046692: AB_2679755" "unprognostic (1.01e-2)" "unprognostic (2.81e-1)" "unprognostic (5.20e-2)" "unprognostic (3.39e-3)" "prognostic favorable (1.28e-4)" "unprognostic (1.21e-1)" "unprognostic (9.35e-2)" "prognostic favorable (8.57e-4)" "unprognostic (5.24e-2)" "unprognostic (3.52e-2)" "unprognostic (2.53e-1)" "unprognostic (2.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (3.55e-1)" "unprognostic (3.24e-2)" "unprognostic (5.71e-2)" 7.8 12.0 11.0 7.8 11.9 1.3 12.8 12.1 12.4 15.4 10.9 8.8 9.3 15.5 13.3 8.6 11.4 9.8 7.7 10.2 12.0 11.8 9.3 9.9 9.9 11.8 11.5 17.9 8.2 17.7 7.1 11.2 12.4 14.9 10.9 14.3 8.7 13.9 6.6 6.0 8.1 10.5 12.0 11.7 9.1 11.1 11.6 10.1 15.3 12.8 9.7 10.8 7.4 15.0 9.3 6.8 26.2 31.0 17.3 22.5 9.7 12.3 16.1 16.6 20.1 13.3 5.5 11.0 28.5 10.6 20.8 11.5 19.7 7.4 20.8 17.3 18.0 19.5 8.7 13.2 19.5 0.0 17.3 14.1 27.0 10.7 12.3 20.8 14.4 13.5 23.3 11.7 18.3 5.2 14.1 16.9 7.8 8.5 8.4 15.4 18.6 16.0 10.1 14.5 21.3 22.7 14.5 13.6 25.9 12.8 12.5 12.8 14.4 27.8 11.0 11.4 12.4 12.2 25.8 10.8 5.8 2.9 28.4 3.3 8.4 10.8 10.5 7.2 7.6 11.2 5.3 6.9 6.9 9.0 6.1 9.1 8.0 17.8 11.9 7.8 4.5 5.1 11.0 11.9 12.1 12.4 10.2 12.0 11.8 11.5 12.4 12.0 11.6 15.0 24.8 6.4 10.5 3.9 18.0 4.0 17.3 4.8 14.8 32.1 23.9 31.2 5.8 12.8 11.1 9.2 8.4 12.5 16.1 9.9 35.2 17.7 4.1 14.2 32.6 20.1 19.7 7.2 5.3 10.2 11.3 21.9 10.2 15.7 13.3 30.0 18.2 7.6 13.3 47.1 7.0 14.1 8.2 8.9 5.3 3.7 30.1 11.7 8.8 6.5 12.7 26.7 10.3 11.1 10.3 16.1 12.8 26.4 11.8 26.4 10.2 13.3 8.1 13.9 32.9 20.6 22.2 26.0 15.7 12.0 6.5 9.6 9.1 37.7 10.0 24.9 ZNF324 "ZF5128, ZNF324A" ENSG00000083812 "Zinc finger protein 324" O75467 19 58467045-58475436 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 37.0;Horizontal cells: 33.7;Rod photoreceptor cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 54.2" HPA039774 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear membrane, Cytosol" "HPA039774: AB_10673149" "unprognostic (8.60e-2)" "unprognostic (7.42e-3)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (5.12e-3)" "unprognostic (3.69e-3)" "unprognostic (2.36e-2)" "unprognostic (5.09e-3)" "unprognostic (2.84e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.74e-5)" "unprognostic (6.39e-2)" "prognostic favorable (1.34e-7)" "unprognostic (1.19e-1)" "unprognostic (8.27e-2)" "prognostic unfavorable (6.99e-4)" "unprognostic (3.56e-1)" 3.4 3.9 4.8 3.4 4.9 6.7 3.7 6.3 6.0 4.6 2.8 4.1 4.3 5.0 3.2 5.9 5.2 2.9 3.4 5.1 4.2 3.1 5.7 3.2 3.1 4.7 3.9 5.8 7.0 4.4 6.6 2.9 3.8 4.6 2.2 3.0 4.7 4.2 3.0 6.6 3.9 3.3 2.9 3.9 4.4 4.4 3.4 6.8 4.8 2.6 2.9 4.4 3.8 4.8 7.8 8.9 5.0 10.1 5.3 5.0 7.2 6.3 6.4 5.6 5.0 8.5 4.2 11.2 5.9 4.3 7.6 9.3 6.4 6.6 2.1 10.5 54.2 6.9 6.7 3.6 4.5 12.3 9.2 3.9 8.5 7.1 3.3 5.1 3.7 7.9 11.4 7.1 6.0 6.0 12.5 6.6 5.4 6.4 12.9 13.9 6.5 7.3 3.8 15.5 11.8 9.5 6.5 10.8 3.8 3.6 4.9 10.1 6.4 17.6 3.9 6.4 11.2 10.4 12.0 5.8 9.5 6.7 6.5 2.3 5.3 8.9 10.5 5.9 11.5 5.8 8.0 11.6 3.8 6.2 12.1 9.7 15.6 7.3 4.5 7.0 8.8 4.2 4.8 4.9 6.3 6.0 5.1 4.2 4.7 3.9 3.8 2.9 3.4 4.8 4.8 0.0 1.7 5.2 8.4 9.1 5.5 3.1 2.2 37.0 10.3 7.5 7.5 2.8 3.8 0.0 25.0 4.8 6.9 9.9 0.0 4.9 1.2 6.3 6.3 5.5 7.8 6.5 5.6 4.1 3.8 6.0 6.6 3.6 1.3 11.3 7.5 3.6 2.9 33.7 6.3 7.9 6.1 2.4 3.7 1.6 12.8 3.2 3.6 7.5 4.1 15.8 7.2 4.5 6.7 4.2 12.4 14.7 5.6 8.0 9.0 2.3 5.8 57.2 6.6 11.7 8.5 19.4 15.8 4.8 13.4 6.7 7.6 11.2 6.3 3.8 ZNF326 "FLJ20403, ZAN75, Zfp326, ZIRD" ENSG00000162664 "Zinc finger protein 326" Q5BKZ1 1 89995110-90035533 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 52.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 373.2;Rod photoreceptor cells: 458.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028450, HPA028461, HPA028466" Supported Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 79: Retina - Phototransduction" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Golgi apparatus, Vesicles" "HPA028450: AB_2672616, HPA028461: AB_10601777, HPA028466: AB_10601677" "prognostic favorable (9.46e-4)" "unprognostic (2.45e-1)" "unprognostic (7.25e-3)" "unprognostic (1.09e-1)" "unprognostic (5.28e-3)" "unprognostic (1.67e-2)" "unprognostic (8.61e-3)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (3.17e-2)" "unprognostic (3.66e-2)" "unprognostic (1.33e-2)" "unprognostic (2.62e-2)" "unprognostic (8.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.29e-1)" "prognostic favorable (2.84e-4)" 11.0 9.5 5.9 5.5 7.2 21.0 11.1 8.9 6.7 13.5 6.8 12.8 8.8 12.5 7.4 15.3 11.0 5.3 10.4 7.1 5.2 12.2 12.8 8.5 6.9 7.3 6.5 17.2 17.0 4.5 10.3 6.2 7.3 9.3 8.5 52.6 13.4 3.9 9.8 10.2 12.6 5.0 6.7 8.0 10.3 6.9 5.8 5.3 10.9 2.4 6.0 9.6 12.4 10.2 9.2 6.9 17.9 7.1 6.1 4.3 16.4 11.1 4.5 6.6 5.0 7.2 8.1 13.3 5.7 5.6 6.3 9.5 10.8 7.2 8.8 5.9 7.2 10.6 14.3 7.0 2.4 12.6 6.1 4.3 4.3 6.8 5.7 8.5 4.6 7.8 11.7 5.8 7.1 4.0 13.3 9.6 11.2 6.1 8.0 11.1 11.1 3.0 6.2 15.5 11.3 10.9 10.1 10.6 5.0 10.2 7.8 4.2 8.0 9.3 7.7 8.3 8.4 7.2 3.8 8.8 2.7 10.1 5.3 1.0 1.1 1.2 0.9 1.4 0.8 0.9 0.8 0.9 0.7 1.5 0.8 1.0 0.8 2.0 1.5 1.7 0.6 0.4 5.9 7.2 8.9 6.7 7.1 5.2 7.3 6.5 7.3 6.7 5.8 10.2 43.0 22.4 50.9 48.0 40.5 65.1 61.5 43.3 37.0 140.8 35.3 39.0 39.2 28.6 43.4 23.9 373.2 46.4 46.7 81.6 19.6 54.2 5.1 45.0 50.3 43.5 70.3 66.9 29.1 54.8 85.3 35.6 35.2 48.9 51.8 68.4 29.6 35.1 26.1 69.0 35.1 47.8 38.7 19.4 38.2 7.3 43.2 34.0 39.2 28.1 40.9 57.0 28.8 58.8 61.3 47.7 70.6 33.8 33.0 53.8 61.0 19.6 44.6 458.4 26.3 45.0 53.6 58.5 35.8 53.2 45.3 49.4 31.6 71.0 50.0 82.0 ZNF33A "FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK" ENSG00000189180 "Zinc finger protein 33A" Q06730 10 38010650-38065088 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: AB_2683199" "unprognostic (1.85e-2)" "unprognostic (1.19e-1)" "unprognostic (7.68e-3)" "unprognostic (1.48e-1)" "unprognostic (3.42e-2)" "unprognostic (1.69e-3)" "unprognostic (7.96e-3)" "unprognostic (4.89e-3)" "unprognostic (6.73e-2)" "unprognostic (9.06e-2)" "unprognostic (2.29e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (6.83e-2)" "unprognostic (7.39e-3)" 9.2 12.6 5.8 12.2 7.0 12.2 17.9 17.1 7.6 14.5 9.6 12.2 13.4 15.1 10.9 9.3 14.9 11.8 9.0 5.0 7.8 15.3 16.3 10.1 14.8 9.5 7.1 14.8 16.9 17.1 14.0 11.4 9.9 15.1 15.8 20.6 14.9 14.3 13.9 13.9 13.7 10.3 6.7 14.2 16.7 4.3 6.8 14.0 15.7 15.8 16.2 11.0 10.3 8.4 16.3 9.1 16.2 14.1 7.8 9.8 12.8 7.3 7.1 9.1 10.2 9.7 14.5 31.5 7.7 9.8 5.2 10.6 19.3 12.6 8.5 18.9 22.0 25.2 18.6 13.2 7.9 36.0 20.2 8.6 22.5 6.9 10.1 17.0 7.5 17.7 13.5 16.5 9.3 10.6 15.0 8.2 16.4 8.2 10.5 12.9 11.2 14.8 12.8 15.0 12.6 19.8 11.3 12.3 6.4 11.2 14.8 9.5 7.3 8.0 11.7 9.0 5.8 13.0 17.1 18.5 7.4 19.7 3.7 12.7 3.6 6.1 5.4 5.0 4.7 6.4 4.7 3.6 3.4 6.2 5.8 4.6 15.9 4.7 6.6 6.3 3.6 3.1 5.8 7.0 17.1 7.6 5.0 7.8 9.5 7.1 9.9 6.7 6.8 8.4 28.4 60.9 73.0 39.8 47.5 11.9 33.0 25.6 19.4 38.2 33.4 28.6 70.6 31.5 49.0 27.6 33.3 28.4 43.1 27.1 25.4 34.9 4.6 62.8 19.3 31.6 34.1 30.3 47.4 29.2 20.0 23.5 25.5 37.7 33.6 47.6 21.4 39.6 19.4 30.3 63.9 28.2 18.3 22.8 16.8 6.7 23.9 26.1 10.6 58.1 46.9 21.1 38.1 56.3 81.5 32.0 29.6 24.0 32.1 38.9 22.0 39.3 80.8 31.8 26.3 32.7 22.7 15.3 18.9 18.7 12.8 35.6 34.6 33.2 27.5 38.4 ZNF33B "KOX2, KOX31, ZNF11B" ENSG00000196693 "Zinc finger protein 33B" Q06732 10 42574185-42638570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: AB_2683199" "unprognostic (3.01e-3)" "unprognostic (2.20e-1)" "unprognostic (2.93e-2)" "unprognostic (8.34e-2)" "unprognostic (5.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.43e-2)" "unprognostic (1.18e-1)" "unprognostic (3.73e-1)" "unprognostic (3.79e-2)" "unprognostic (2.90e-3)" "unprognostic (3.71e-1)" "unprognostic (1.27e-1)" "unprognostic (5.60e-2)" "unprognostic (1.61e-2)" 4.7 9.8 3.9 5.9 4.9 3.1 20.6 9.8 5.1 9.5 9.5 9.1 8.9 11.7 7.6 7.4 18.6 8.6 5.3 4.8 6.6 18.5 10.3 8.9 9.4 4.9 4.0 23.5 34.1 15.2 10.0 7.2 5.1 12.6 10.4 10.4 18.6 10.4 3.9 12.2 9.7 5.2 2.5 10.3 14.3 4.7 5.3 8.0 18.3 4.9 8.9 9.0 9.0 3.7 13.2 3.3 8.5 8.8 3.1 0.4 10.6 8.1 6.2 5.1 7.1 7.3 14.9 19.9 4.8 3.1 7.7 10.9 16.5 5.6 5.7 11.8 12.4 7.9 12.7 11.9 3.6 18.8 6.2 5.1 20.1 3.1 17.0 13.4 4.4 10.8 10.9 14.7 3.1 5.7 7.5 4.5 9.3 6.5 7.7 8.0 8.5 8.5 13.4 17.2 15.3 14.9 5.1 10.5 5.1 7.7 13.4 5.7 5.3 2.6 12.3 4.5 8.6 9.5 15.5 6.1 1.8 13.9 2.4 19.4 7.5 7.1 10.7 6.7 15.1 20.1 15.4 10.8 6.7 15.4 19.5 13.7 2.4 8.3 5.5 11.1 13.4 9.0 3.9 4.9 9.8 5.1 4.8 6.6 4.9 4.0 5.1 2.5 5.3 3.7 10.0 80.1 37.8 14.0 17.7 4.8 18.0 5.5 18.2 15.4 26.0 27.8 31.5 34.3 30.0 20.2 10.4 18.6 13.4 9.7 21.5 27.0 2.4 37.2 6.0 14.1 25.3 17.1 25.6 36.1 16.8 10.0 14.8 14.5 8.2 23.8 16.4 10.8 8.4 10.1 48.2 17.6 4.1 13.6 3.6 3.8 20.5 9.3 7.2 36.5 17.9 10.2 21.6 30.7 14.1 25.8 21.4 11.7 15.2 13.0 21.2 27.0 47.6 9.6 0.0 9.0 8.5 9.0 11.3 11.8 4.0 11.5 17.0 22.6 18.5 12.8 ZNF341 dJ553F4.3 ENSG00000131061 "Zinc finger protein 341" Q9BYN7 20 33731657-33792269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023240, HPA024607, HPA067108" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA023240: AB_1859207, HPA024607: AB_1859208, HPA067108: AB_2685780" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (3.73e-1)" "unprognostic (2.10e-1)" "unprognostic (9.31e-2)" "prognostic favorable (3.93e-4)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.44e-1)" "unprognostic (1.70e-1)" "unprognostic (1.80e-1)" "unprognostic (7.38e-2)" "unprognostic (9.31e-2)" "unprognostic (8.17e-5)" "unprognostic (4.84e-2)" "unprognostic (2.90e-1)" "unprognostic (8.67e-3)" "unprognostic (3.68e-2)" 1.2 0.9 1.0 1.9 1.1 2.4 0.9 0.8 2.2 1.1 0.0 1.5 1.4 1.3 1.0 1.3 1.3 0.9 1.0 1.6 0.2 0.6 0.6 1.1 1.9 0.3 0.1 1.3 1.6 0.9 0.6 1.4 0.4 1.3 1.1 0.7 1.5 1.0 3.3 2.1 1.0 1.2 0.2 1.9 1.4 1.5 0.5 1.8 0.9 3.3 1.2 1.2 1.1 1.3 2.4 6.4 2.2 4.7 2.1 1.7 9.5 2.3 1.2 1.9 1.2 4.6 5.4 3.7 3.8 1.7 2.2 3.7 2.4 4.1 0.8 3.3 2.2 3.6 3.6 3.7 1.2 2.1 4.3 1.4 3.0 1.6 1.0 1.7 2.3 3.4 1.9 1.7 2.0 2.9 1.9 1.6 3.0 3.5 3.1 2.4 1.4 2.1 1.3 5.2 1.9 2.1 6.1 5.6 1.4 1.7 5.0 1.7 2.9 3.4 1.4 2.5 2.2 1.3 1.9 3.4 3.3 1.7 2.4 2.6 1.3 2.9 1.1 1.8 1.0 2.2 0.8 0.7 1.0 1.2 0.5 1.5 2.5 1.3 1.2 0.7 0.6 0.9 1.0 1.1 0.8 2.2 1.6 0.2 0.3 0.1 0.4 0.2 0.5 1.3 1.8 3.2 5.1 5.5 2.9 0.4 1.0 1.5 0.6 2.2 1.9 1.4 2.7 2.8 4.7 1.8 2.1 2.6 0.9 7.0 0.0 1.5 0.6 1.6 1.4 1.4 1.2 0.8 11.3 1.4 3.3 1.6 6.6 2.1 2.5 1.8 1.4 1.0 1.4 1.7 8.0 2.0 2.0 1.6 2.0 0.1 0.6 2.4 0.0 3.7 1.2 0.6 2.1 6.0 7.7 1.7 2.5 0.4 2.6 2.5 4.2 0.4 4.6 2.3 0.0 1.9 1.1 1.6 2.4 1.6 1.0 2.1 1.9 1.5 2.4 2.5 ZNF354A "EZNF, HKL1, KID-1, KID1, TCF17" ENSG00000169131 "Zinc finger protein 354A" O60765 5 178711512-178730659 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 49.6" "Low region specificity" "Detected in all" HPA052043 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" Cytosol "HPA052043: AB_2681706" "unprognostic (2.79e-1)" "unprognostic (3.44e-2)" "unprognostic (7.06e-3)" "unprognostic (1.78e-3)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (3.25e-2)" "unprognostic (1.41e-1)" "unprognostic (7.66e-3)" "prognostic favorable (8.28e-4)" "unprognostic (4.06e-2)" "unprognostic (4.55e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (8.71e-2)" "unprognostic (4.13e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" 8.3 5.3 7.8 7.7 7.6 9.4 8.3 7.4 9.3 9.5 6.8 12.4 4.3 8.6 7.6 6.9 8.8 5.8 7.7 7.8 6.9 11.7 4.8 8.1 8.4 7.1 7.3 7.6 11.1 8.1 6.5 8.5 7.3 9.7 5.8 8.5 6.3 8.4 7.5 7.5 8.2 8.0 6.7 12.6 7.9 10.5 7.7 8.4 10.8 8.1 8.8 9.9 8.3 7.9 7.6 5.8 12.0 31.9 20.4 16.4 49.6 8.6 11.4 11.7 12.5 8.7 12.5 10.1 11.1 7.9 21.5 14.9 4.5 37.6 17.8 13.7 13.8 3.1 8.0 1.1 15.4 0.0 8.3 12.9 22.9 10.3 20.8 15.1 11.3 13.5 2.5 0.0 17.2 15.4 15.5 10.2 10.5 7.0 15.0 11.6 2.1 6.5 10.9 7.6 13.1 14.3 10.9 12.3 17.0 15.7 10.1 14.9 8.8 13.2 8.6 7.5 7.4 3.3 7.2 6.3 0.5 2.3 16.9 4.5 6.0 15.6 4.9 4.0 6.1 5.4 4.3 5.5 5.4 3.5 4.8 3.6 15.8 6.1 4.1 2.0 4.4 3.6 7.8 7.6 7.4 9.3 7.8 6.9 7.1 7.3 7.3 6.7 7.7 7.9 10.7 12.8 7.4 8.8 7.5 5.0 11.7 14.1 4.0 9.0 8.2 9.3 6.6 4.3 11.3 7.3 14.6 12.8 12.6 3.7 13.7 11.3 18.8 5.9 9.0 9.0 4.8 7.8 18.6 7.6 14.6 9.5 3.6 5.7 6.3 14.3 4.6 1.5 8.9 6.7 10.9 2.7 8.2 7.7 8.2 4.7 6.8 8.2 10.6 10.3 7.6 9.2 16.5 12.5 13.3 7.2 1.4 10.5 3.2 10.7 4.1 17.0 9.5 10.5 6.6 10.1 9.4 36.2 12.0 4.8 5.5 12.2 9.2 10.9 4.3 7.7 ZNF397 "MGC13250, ZNF47, ZSCAN15" ENSG00000186812 "Zinc finger protein 397" Q8NF99 18 35241030-35267133 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026087 Uncertain Approved "Nucleoli,Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli, Plasma membrane, Cytosol" Microtubules "HPA026087: AB_1859243" "unprognostic (1.97e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "unprognostic (3.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.15e-2)" "unprognostic (1.74e-3)" "unprognostic (1.45e-2)" "unprognostic (1.48e-2)" "unprognostic (3.28e-2)" "prognostic favorable (9.44e-4)" "unprognostic (2.46e-2)" "unprognostic (2.17e-3)" "unprognostic (3.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.09e-3)" 12.9 13.4 17.6 14.4 23.4 5.0 16.1 19.1 20.0 13.5 14.9 12.8 10.6 15.7 12.4 9.8 11.7 10.1 10.5 16.4 20.7 11.3 10.6 10.4 16.2 20.5 20.9 17.8 12.4 14.8 12.0 11.9 20.1 13.9 13.9 25.0 12.4 12.1 11.7 13.6 12.6 11.5 15.4 16.1 13.3 9.9 20.3 13.1 15.7 11.0 15.8 11.9 11.8 34.4 4.2 7.9 18.7 17.1 20.3 17.0 8.9 8.4 8.3 4.1 5.4 3.0 5.7 21.2 7.4 6.7 5.6 11.1 12.2 9.2 5.7 13.5 7.5 0.9 11.7 8.6 6.7 10.3 7.4 7.7 12.1 4.9 14.1 14.6 2.6 16.1 12.7 14.4 10.7 9.1 17.4 7.8 16.1 3.2 3.2 18.2 5.4 15.1 8.4 11.0 20.2 17.4 13.7 7.2 8.2 16.2 12.5 7.6 4.2 13.6 7.6 4.6 3.8 23.2 9.3 11.9 12.0 7.1 13.1 10.1 4.6 8.3 5.7 7.5 4.1 10.6 5.3 4.7 3.3 11.3 7.8 5.4 11.0 4.7 9.4 7.5 3.0 2.2 17.6 23.4 19.1 20.0 16.4 20.7 20.5 20.9 20.1 15.4 20.3 34.4 15.5 35.3 21.0 24.5 35.3 4.1 19.4 8.0 10.2 51.0 11.8 10.4 16.4 15.7 17.3 14.7 35.5 22.6 15.8 14.1 13.7 18.7 66.0 10.8 20.4 17.6 31.0 20.4 17.4 10.9 13.4 18.4 12.8 8.9 11.4 31.7 31.1 12.6 10.8 33.7 19.5 11.5 12.2 20.5 5.4 49.6 18.6 11.8 8.8 23.4 20.3 24.6 15.5 30.2 94.1 10.7 18.3 22.6 6.1 15.8 24.3 11.4 16.4 46.1 32.9 25.3 16.6 29.7 23.4 7.8 4.5 14.6 13.9 22.1 16.1 11.1 ZNF404 ENSG00000176222 "Zinc finger protein 404" Q494X3 19 43872365-43901385 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Oligodendrocytes: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2 OS: 43.7" "Low region specificity" "Detected in all" "HPA032014, HPA063607" Uncertain Supported "Nucleoli,Nucleoli rim,Intermediate filaments" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 9: U-2 OS - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Nucleoli rim" "Intermediate filaments" "HPA032014: AB_10602591, HPA063607: AB_2732705" "unprognostic (3.76e-3)" "unprognostic (3.41e-1)" "unprognostic (1.11e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-2)" "unprognostic (2.82e-1)" "unprognostic (1.64e-2)" "unprognostic (2.68e-2)" "unprognostic (7.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.03e-5)" "unprognostic (1.46e-2)" "unprognostic (3.79e-3)" "unprognostic (2.89e-2)" "unprognostic (1.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.80e-3)" 2.4 3.2 9.2 1.1 10.3 0.6 2.7 9.7 11.3 3.8 8.3 5.8 0.6 2.4 9.6 2.0 6.4 2.4 9.1 8.8 9.3 3.9 2.3 2.1 3.6 9.9 9.7 6.8 2.4 2.5 14.3 2.9 9.9 6.1 1.8 18.0 2.8 2.3 2.6 3.1 2.7 2.0 9.7 5.4 3.2 4.6 10.3 2.3 4.2 1.9 1.6 4.6 2.9 12.0 3.4 0.5 3.4 0.4 8.4 11.8 2.0 4.6 2.2 2.9 4.0 0.3 1.2 0.0 4.7 2.2 0.1 0.4 0.6 2.3 3.9 0.5 3.3 1.2 0.1 1.3 3.0 0.3 0.9 7.1 5.5 2.1 2.0 9.8 2.5 0.0 0.1 0.0 2.7 0.3 0.0 0.1 2.8 0.1 0.7 0.0 1.8 0.7 2.8 2.2 1.8 1.4 1.9 0.8 2.4 6.1 0.1 1.3 1.1 4.1 43.7 3.7 2.7 5.8 8.1 0.0 5.8 0.0 2.4 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.3 0.3 0.0 0.5 0.0 0.2 0.3 0.1 9.2 10.3 9.7 11.3 8.8 9.3 9.9 9.7 9.9 9.7 10.3 12.0 1.3 0.0 3.2 21.5 1.5 0.0 0.7 1.1 0.6 3.6 1.3 1.9 7.0 0.0 0.9 0.0 0.0 1.5 0.3 0.2 0.0 0.7 1.5 1.6 3.2 1.5 2.4 0.4 6.9 0.2 1.1 1.6 0.5 1.1 7.0 2.9 1.1 0.5 0.7 5.0 6.9 0.6 4.1 0.3 0.3 0.3 0.9 0.7 0.0 1.9 0.4 3.8 2.1 3.0 19.4 0.2 0.5 3.4 0.1 0.8 0.7 0.4 1.9 3.3 0.0 0.4 1.3 1.7 3.2 0.4 0.0 1.0 1.5 0.5 0.9 0.5 ZNF44 "KOX7, ZNF504, ZNF55, ZNF58" ENSG00000197857 "Zinc finger protein 44" P15621 19 12224686-12294883 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 95.9;Early spermatids: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA003146 Supported Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Microtubules, Cytosol" "HPA003146: AB_1080723" "unprognostic (1.51e-1)" "unprognostic (2.47e-3)" "unprognostic (7.07e-2)" "unprognostic (4.60e-2)" "unprognostic (9.63e-2)" "prognostic favorable (8.74e-4)" "unprognostic (8.39e-2)" "prognostic favorable (7.54e-4)" "unprognostic (5.65e-3)" "unprognostic (9.17e-2)" "unprognostic (1.75e-3)" "unprognostic (3.56e-3)" "unprognostic (7.30e-3)" "unprognostic (2.75e-1)" "unprognostic (2.09e-1)" "unprognostic (5.69e-2)" "prognostic favorable (9.21e-6)" 6.9 5.7 2.5 2.7 2.7 9.6 6.8 3.8 3.1 7.5 3.8 6.9 3.3 5.4 5.2 6.8 6.3 2.1 5.2 2.5 2.7 12.1 11.0 6.1 4.4 2.8 2.7 9.4 6.8 4.0 7.1 2.7 2.8 7.4 4.9 5.0 5.7 3.1 3.5 7.9 7.4 2.6 2.3 9.4 5.0 9.7 2.8 3.2 6.7 2.4 4.2 7.0 6.9 3.4 3.0 0.9 1.8 4.3 2.1 1.9 9.6 4.2 1.7 6.5 5.9 4.2 1.7 3.0 5.0 3.4 1.9 3.2 3.0 2.6 5.6 0.0 2.7 2.9 4.4 11.3 2.9 0.0 7.4 2.5 3.9 4.1 4.9 2.6 2.6 3.8 1.9 0.6 4.2 3.2 4.6 5.7 1.8 3.0 5.2 3.2 4.7 3.8 3.7 7.1 2.6 2.9 5.4 2.2 1.4 6.2 4.5 4.6 2.8 8.3 2.3 8.3 3.7 6.5 7.5 2.8 0.2 2.7 2.4 11.9 1.7 15.8 7.3 3.2 8.5 4.2 7.9 7.9 1.3 3.4 8.4 8.4 5.6 11.5 3.2 3.2 6.1 3.4 2.5 2.7 3.8 3.1 2.5 2.7 2.8 2.7 2.8 2.3 2.8 3.4 14.6 28.9 19.9 16.6 16.1 9.1 6.6 8.2 8.0 16.1 10.6 8.3 16.9 17.2 13.9 64.4 37.5 17.2 21.5 17.9 95.9 9.9 113.1 21.1 11.6 11.8 15.6 6.5 13.8 9.3 6.8 8.3 6.1 25.1 24.1 14.4 11.0 12.4 8.5 16.8 16.1 12.9 10.2 11.1 8.7 34.1 14.0 10.9 10.6 25.3 8.8 9.8 27.8 17.6 21.7 9.6 13.0 6.0 13.7 6.2 17.1 13.6 24.8 36.7 19.7 11.6 9.8 36.5 24.8 16.4 11.6 8.6 19.2 8.4 12.9 9.6 ZNF445 "ZKSCAN15, ZNF168, ZSCAN47" ENSG00000185219 "Zinc finger protein 445" P59923 3 44431705-44477670 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006678 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 72: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Mitochondria, Cytosol" "HPA006678: AB_10603329" "unprognostic (7.72e-2)" "unprognostic (2.55e-1)" "unprognostic (1.12e-2)" "unprognostic (1.42e-1)" "unprognostic (7.14e-2)" "unprognostic (1.67e-2)" "unprognostic (1.79e-2)" "unprognostic (2.72e-2)" "unprognostic (1.60e-2)" "unprognostic (1.62e-1)" "unprognostic (1.03e-2)" "unprognostic (4.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.76e-1)" "unprognostic (2.48e-1)" "unprognostic (4.40e-3)" "unprognostic (1.05e-1)" 4.2 3.0 2.3 1.8 2.5 1.3 3.9 4.3 2.4 6.0 1.1 4.7 1.4 5.1 2.0 2.7 5.0 1.6 3.6 2.4 2.4 3.3 4.9 4.1 1.9 2.1 2.1 7.0 4.4 2.8 5.0 2.0 2.2 4.4 1.7 4.2 3.6 2.1 4.4 3.7 3.5 2.2 1.7 3.9 3.9 3.1 2.2 3.3 3.8 2.7 2.1 4.1 4.4 2.9 1.9 2.1 6.4 5.1 3.5 3.6 2.9 2.5 2.1 3.7 3.7 3.2 1.6 3.3 1.5 2.6 2.3 1.5 4.4 1.7 4.5 3.6 1.6 6.1 4.7 3.2 2.2 7.8 4.9 2.5 2.1 4.2 2.6 3.1 2.6 4.6 4.8 2.4 3.0 1.2 7.5 5.2 4.4 1.2 1.9 3.3 4.0 1.6 2.0 3.8 3.2 3.9 3.9 2.0 1.0 4.7 3.7 3.4 3.2 5.2 4.6 3.2 3.2 1.9 1.5 2.7 1.9 3.8 3.2 1.0 0.3 0.6 0.3 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.3 0.2 1.0 0.5 0.8 0.3 0.1 0.1 2.3 2.5 4.3 2.4 2.4 2.4 2.1 2.1 2.2 1.7 2.2 2.9 11.7 12.8 17.4 19.2 8.4 4.1 4.4 2.9 9.6 36.0 4.8 4.4 11.1 5.7 7.6 11.0 37.5 4.1 15.7 3.8 1.9 5.8 2.5 6.3 14.1 9.7 7.2 10.3 21.7 8.4 1.7 9.0 7.1 6.8 11.4 26.6 13.2 10.1 5.7 28.6 24.3 6.3 2.0 16.4 4.7 2.2 9.3 10.5 0.0 9.4 11.6 10.1 22.6 11.6 19.5 4.9 6.0 9.8 9.5 5.6 4.3 2.8 9.6 28.4 13.1 14.5 10.6 6.7 6.9 5.6 2.6 1.4 9.8 9.3 7.2 3.8 ZNF461 "GIOT-1, MGC33911" ENSG00000197808 "Zinc finger protein 461" Q8TAF7 19 36636618-36666853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Alveolar cells type 2: 23.8;Early spermatids: 43.5;granulocytes: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021139 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA021139: AB_10961418" "unprognostic (8.37e-3)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.08e-2)" "unprognostic (6.32e-2)" "unprognostic (5.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-3)" "unprognostic (2.11e-1)" "unprognostic (7.01e-3)" "unprognostic (2.43e-2)" "unprognostic (1.51e-1)" "unprognostic (4.21e-2)" "unprognostic (4.54e-2)" "unprognostic (5.86e-2)" "unprognostic (5.11e-3)" 2.2 3.6 3.5 2.0 3.4 3.0 3.0 6.2 5.2 2.0 1.7 2.2 0.5 3.3 2.5 2.1 3.0 2.0 2.3 3.5 3.4 2.7 2.0 2.0 3.2 2.3 2.6 4.4 1.3 3.2 3.0 3.4 2.6 2.8 1.9 6.6 1.6 2.2 2.2 3.0 1.9 3.2 2.4 3.5 2.5 3.7 3.5 2.5 4.1 2.1 3.2 2.0 2.0 3.7 2.9 4.7 3.5 4.8 2.6 4.9 2.4 2.9 3.0 4.2 5.8 0.8 1.4 0.4 6.2 3.8 4.2 0.6 2.5 3.0 4.6 5.6 3.4 4.9 0.7 1.9 4.1 3.7 5.5 3.5 5.6 1.5 4.3 5.6 2.6 2.4 0.2 0.5 4.3 2.7 6.1 1.7 2.3 0.4 2.1 0.4 3.6 1.0 1.8 6.3 4.6 6.1 0.3 2.1 3.8 3.5 2.2 1.5 3.2 2.5 3.4 2.1 3.7 7.6 12.2 1.6 0.0 0.8 3.6 0.8 0.5 0.5 1.3 1.1 1.7 1.5 2.1 2.8 1.2 2.0 1.6 1.3 0.1 1.4 0.2 0.5 2.0 0.9 3.5 3.4 6.2 5.2 3.5 3.4 2.3 2.6 2.6 2.4 3.5 3.7 2.3 28.9 23.8 8.1 4.1 3.3 2.0 2.3 4.6 5.4 4.7 2.5 2.2 7.2 12.9 3.7 0.0 2.5 2.6 0.9 1.9 1.7 43.5 4.6 2.9 5.2 3.0 0.8 16.3 0.9 2.9 6.2 1.5 4.6 33.5 3.1 2.9 1.2 1.7 3.3 14.0 1.1 0.0 2.5 3.2 8.3 0.9 3.2 0.0 4.7 0.9 1.6 1.0 9.0 12.4 0.8 0.5 1.9 1.2 2.3 0.8 1.8 9.9 3.6 0.0 4.9 3.9 10.2 4.0 3.1 3.4 2.9 6.1 1.9 1.3 1.8 ZNF484 "BA526D8.4, FLJ33884" ENSG00000127081 "Zinc finger protein 484" Q5JVG2 9 92844182-92878038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.7;Inhibitory neurons: 22.6;Oligodendrocyte precursor cells: 27.2;Oligodendrocytes: 19.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028973 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028973: AB_10610703" "unprognostic (5.52e-2)" "unprognostic (3.05e-2)" "unprognostic (1.72e-1)" "unprognostic (6.05e-2)" "unprognostic (5.69e-2)" "unprognostic (3.86e-1)" "unprognostic (6.45e-2)" "unprognostic (1.91e-1)" "unprognostic (6.04e-2)" "unprognostic (9.84e-2)" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (4.03e-2)" "unprognostic (3.74e-1)" "unprognostic (4.77e-1)" "unprognostic (6.49e-2)" "unprognostic (1.51e-1)" 2.0 2.2 1.9 2.0 2.7 4.1 2.2 9.7 3.3 2.5 0.0 1.6 1.2 2.4 1.7 1.3 2.1 1.6 1.6 1.8 3.4 2.4 1.9 2.0 2.4 2.8 2.8 3.1 1.3 3.6 2.1 2.8 3.1 2.3 1.8 5.3 1.5 2.0 1.1 1.3 1.5 2.1 2.7 2.9 2.1 1.7 3.5 2.6 3.1 2.3 2.8 2.1 1.8 4.0 3.1 3.6 4.7 3.0 2.4 3.0 0.0 2.4 3.8 4.2 4.4 1.2 2.2 2.5 2.1 1.9 2.9 5.0 3.5 3.7 4.4 4.2 1.5 2.2 3.1 2.4 3.7 1.9 3.7 3.3 2.7 4.7 4.9 3.2 3.9 2.8 2.4 10.6 4.5 2.9 2.7 0.8 4.0 3.4 1.7 2.2 5.8 1.9 2.3 3.4 3.2 3.0 4.3 1.2 2.4 3.5 0.2 1.5 3.7 3.7 3.7 2.0 1.8 3.9 2.1 1.5 2.4 1.5 3.1 0.6 1.2 2.8 2.4 1.8 3.1 1.8 2.6 2.1 1.1 2.6 3.4 3.2 0.7 2.4 1.6 1.3 2.2 1.5 1.9 2.7 9.7 3.3 1.8 3.4 2.8 2.8 3.1 2.7 3.5 4.0 6.2 0.0 1.5 9.8 13.2 0.1 0.7 1.1 6.8 5.0 1.6 0.9 2.2 0.0 4.7 1.8 0.0 1.2 6.3 0.9 1.9 1.3 0.7 1.3 4.4 4.9 0.0 3.4 17.7 0.4 1.2 4.3 5.6 1.3 2.5 3.6 0.7 0.6 0.8 5.0 22.6 1.4 4.1 0.6 0.4 0.9 0.6 2.7 0.0 12.2 1.2 3.1 5.2 27.2 19.1 0.7 1.6 1.5 5.8 0.6 0.9 1.5 4.1 3.8 0.0 3.7 4.8 0.8 0.7 3.9 0.1 0.7 9.3 3.3 0.7 0.6 ZNF487 "KRBO1, ZNF487P" ENSG00000243660 "Zinc finger protein 487" 10 43436841-43483181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.2" "Cell type enhanced" "Detected in many" "Early spermatids: 191.2;Endometrial ciliated cells: 65.7;Late spermatids: 289.9;Respiratory ciliated cells: 73.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA037820 Approved "Nucleoplasm,Nuclear membrane,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA037820: AB_10697083" "unprognostic (1.97e-1)" "unprognostic (1.69e-3)" "unprognostic (1.49e-1)" "unprognostic (3.42e-3)" "unprognostic (7.40e-2)" "unprognostic (1.42e-2)" "unprognostic (7.10e-2)" "unprognostic (4.84e-1)" "unprognostic (4.00e-2)" "unprognostic (1.05e-2)" "unprognostic (6.97e-4)" "unprognostic (5.85e-2)" "unprognostic (3.97e-4)" "unprognostic (2.91e-1)" "unprognostic (4.42e-2)" "unprognostic (2.52e-2)" "unprognostic (5.92e-2)" 2.9 2.1 2.1 2.0 2.1 4.3 2.8 2.0 6.3 3.2 4.5 2.6 2.4 3.8 2.1 2.1 6.0 3.7 2.1 2.3 1.9 2.3 2.2 3.0 2.4 7.5 6.0 4.2 1.6 3.6 2.4 1.9 5.0 2.3 1.9 8.9 1.5 2.7 1.2 2.1 2.5 3.0 4.7 2.4 2.3 28.2 2.2 3.6 3.3 1.6 2.2 3.3 2.1 3.8 1.7 1.6 2.0 2.1 2.4 4.8 0.6 2.7 4.7 2.5 2.7 2.6 4.7 4.3 0.4 3.4 2.4 2.7 0.6 1.0 2.4 0.5 0.9 1.4 0.4 1.5 3.1 1.4 1.7 5.0 2.3 4.2 3.0 5.2 0.9 0.9 0.7 0.6 1.9 3.0 2.9 1.1 0.4 0.8 0.9 1.5 0.7 1.8 5.7 1.9 1.7 1.3 2.4 1.3 1.1 1.2 2.2 1.6 1.5 2.4 1.5 1.4 0.7 0.3 1.1 4.7 5.6 2.0 0.9 1.8 3.0 4.5 3.3 2.2 2.6 1.9 2.4 2.9 3.9 2.5 1.9 2.3 10.4 2.9 1.2 2.9 1.6 2.1 2.1 2.1 2.0 6.3 2.3 1.9 7.5 6.0 5.0 4.7 2.2 3.8 4.0 22.4 4.8 11.8 6.2 1.8 6.3 6.6 3.4 5.4 6.6 7.7 3.3 7.2 8.3 5.5 8.4 1.4 9.8 6.1 11.7 4.5 191.2 65.7 6.5 5.3 7.8 1.3 19.4 2.1 4.0 5.4 5.6 6.3 0.0 3.4 3.3 2.7 3.3 6.7 21.1 4.4 10.2 5.6 3.1 289.9 4.7 6.3 1.8 0.0 7.3 12.6 2.1 6.0 7.1 2.1 3.9 6.8 3.6 3.2 13.0 12.7 73.5 18.7 0.0 6.3 5.1 16.7 7.5 1.9 2.8 1.6 5.6 3.8 3.5 6.1 ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 255.0;Squamous epithelial cells: 189.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 115.1;PC-3: 149.2;U-87 MG: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" 14.5 39.9 6.1 3.1 10.1 2.0 9.2 3.8 5.2 34.5 1.0 17.7 8.1 44.1 10.3 20.1 23.8 2.4 9.0 7.4 5.5 25.6 7.1 14.2 1.5 12.0 9.2 46.3 25.4 4.6 4.8 3.3 7.6 17.5 1.8 1.4 9.5 17.6 3.6 5.3 8.5 7.7 10.0 8.0 16.3 2.4 8.1 1.1 7.8 2.1 1.0 13.8 18.2 6.5 5.2 4.9 1.1 6.3 10.6 7.1 1.6 4.6 2.8 1.9 1.7 7.5 20.4 0.0 13.4 4.6 1.1 9.4 0.7 4.9 1.4 0.0 115.1 0.0 12.4 24.8 8.5 6.1 12.9 19.1 4.8 3.5 2.0 16.6 0.5 0.5 0.1 0.2 2.6 2.7 0.2 18.8 0.1 3.8 149.2 0.0 5.6 0.1 2.8 4.1 4.1 5.2 8.5 0.6 27.1 1.0 1.0 4.2 3.9 14.6 16.3 30.7 13.0 0.0 0.0 0.0 44.9 27.2 11.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 10.1 3.8 5.2 7.4 5.5 12.0 9.2 7.6 10.0 8.1 6.5 27.2 38.5 11.6 2.3 1.7 27.1 35.6 15.0 255.0 23.7 7.7 42.3 20.4 10.0 10.1 40.5 20.9 0.5 2.1 0.8 58.7 45.9 0.1 53.2 72.2 41.0 3.6 5.3 12.6 34.7 0.3 60.1 18.3 48.1 6.3 2.7 44.6 10.3 13.5 6.7 3.2 6.7 10.2 27.4 30.5 2.0 59.7 30.7 24.9 13.1 8.2 7.7 0.0 4.0 0.7 33.2 1.5 49.2 3.9 19.7 13.4 32.5 1.7 26.3 39.5 10.2 78.1 0.2 6.0 189.3 13.9 0.3 4.0 24.5 9.7 14.3 ZNF511 "MGC30006, Zfp511" ENSG00000198546 "Zinc finger protein 511" Q8NB15 10 133308914-133313162 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035360 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931" "unprognostic (3.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (8.84e-2)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-1)" "unprognostic (1.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.94e-2)" "unprognostic (3.91e-2)" "unprognostic (2.55e-1)" "unprognostic (4.52e-2)" 12.7 11.6 15.9 8.7 16.2 17.1 11.3 15.5 17.2 15.8 17.5 19.7 16.1 15.7 10.7 10.8 15.4 9.4 21.2 15.4 15.4 10.4 21.3 11.4 12.6 16.7 15.9 20.4 15.5 14.7 12.7 8.7 15.7 16.1 12.8 5.8 16.7 10.7 49.1 7.9 13.2 11.1 16.4 12.5 12.5 9.6 16.8 11.4 10.9 31.9 9.7 13.6 12.5 16.5 54.1 54.0 30.3 43.8 25.6 21.6 32.6 25.2 39.3 53.3 44.4 88.0 50.9 48.2 24.4 29.5 33.9 48.8 41.9 36.0 23.2 38.8 92.1 29.1 22.1 53.4 21.0 57.5 52.1 22.0 19.2 43.7 26.5 30.6 24.3 22.7 40.0 22.4 18.6 71.2 27.5 76.1 37.3 50.2 74.6 37.1 37.1 12.4 28.3 18.6 16.9 37.0 16.8 30.0 38.2 18.7 23.2 33.1 23.3 23.1 35.4 26.5 68.5 31.3 36.4 66.1 37.5 26.8 12.9 40.2 61.1 68.6 45.4 52.6 35.6 66.6 37.0 46.6 61.0 51.8 41.6 40.8 8.5 41.0 51.1 65.9 36.2 47.3 15.9 16.2 15.5 17.2 15.4 15.4 16.7 15.9 15.7 16.4 16.8 16.5 16.3 16.0 14.5 7.5 33.6 29.6 45.6 40.7 39.3 19.5 37.3 52.6 23.6 25.8 21.9 22.0 8.4 61.2 36.7 33.3 70.5 39.5 29.5 18.5 22.4 20.9 53.4 40.2 10.7 41.2 62.9 34.0 20.4 15.2 78.1 40.6 20.3 54.4 47.4 21.9 7.6 128.8 22.4 33.9 38.0 8.8 41.7 39.9 16.0 5.6 64.3 27.4 41.2 3.5 12.3 38.6 44.0 30.5 40.4 43.0 60.8 72.1 23.2 23.6 26.3 27.3 34.5 58.1 48.0 36.3 35.9 28.2 33.0 38.6 65.9 41.5 ZNF511-PRAP1 ENSG00000283496 "ZNF511-PRAP1 readthrough" 10 133309410-133352529 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 9.2;kidney: 8.4;liver: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.3;RPMI-8226: 1.0" "HPA035360, HPA038713, HPA052451" Supported Uncertain "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931, HPA038713: AB_10673117, HPA052451: AB_2681839" 0.2 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 6.2 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 30.4 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 9.2 0.0 0.1 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.3 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.1 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF526 "KIAA1951, MGC4267" ENSG00000167625 "Zinc finger protein 526" Q8TF50 19 42220312-42228201 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.3;granulocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023070, HPA056609" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA023070: AB_2671057, HPA056609: AB_2683189" "unprognostic (2.04e-1)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (9.09e-3)" "unprognostic (1.79e-1)" "unprognostic (8.84e-2)" "unprognostic (8.62e-3)" "unprognostic (1.28e-2)" "unprognostic (2.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (2.30e-1)" 3.4 2.5 2.1 2.8 2.3 3.8 3.1 4.3 2.6 3.9 2.0 3.3 3.3 3.6 2.3 3.1 3.5 1.9 2.8 2.0 2.1 2.3 2.8 2.6 4.0 2.4 2.2 4.5 3.5 3.9 3.0 3.0 2.3 3.3 2.1 2.0 4.6 3.3 5.1 5.2 3.1 2.4 1.6 3.6 3.1 3.5 2.4 4.2 2.8 4.0 3.6 3.5 3.4 3.4 7.8 24.8 7.1 6.4 8.0 7.7 6.2 8.9 8.2 9.2 10.1 13.0 5.5 12.6 6.3 9.5 4.2 5.7 7.7 9.7 5.7 7.5 9.2 12.6 12.0 12.5 7.5 8.1 7.8 7.6 7.7 9.2 9.6 5.7 5.8 6.7 12.3 7.8 5.9 10.8 8.2 5.2 4.7 6.8 8.7 9.4 8.7 5.7 4.2 14.0 7.3 6.4 10.2 10.1 7.2 5.4 4.1 14.4 7.8 11.3 7.7 4.8 11.2 9.3 5.9 8.5 7.5 7.8 9.5 1.8 3.6 1.4 4.5 3.6 6.9 4.7 3.5 4.1 2.8 4.4 4.2 5.3 0.7 3.4 5.3 4.2 3.9 3.3 2.1 2.3 4.3 2.6 2.0 2.1 2.4 2.2 2.3 1.6 2.4 3.4 3.0 22.4 33.3 2.0 6.9 5.5 4.4 2.8 4.0 7.4 3.1 2.4 3.2 0.0 17.1 3.7 14.6 8.0 3.2 5.7 3.9 4.1 5.8 1.7 4.0 7.1 13.8 9.5 1.4 3.0 8.3 7.4 4.6 2.3 25.2 4.9 3.6 2.6 4.6 6.7 1.5 4.2 2.0 6.8 1.8 6.3 7.2 7.0 0.0 1.9 5.8 4.1 11.3 1.0 1.4 2.9 2.8 3.0 6.1 4.6 7.8 2.8 9.2 9.6 0.0 5.7 3.6 9.9 10.1 1.9 5.1 10.3 6.7 3.7 5.7 2.6 ZNF540 DKFZp547B0714 ENSG00000171817 "Zinc finger protein 540" Q8NDQ6 19 37551406-37614179 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Excitatory neurons: 47.7;Inhibitory neurons: 56.5;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 27.7;Rod photoreceptor cells: 22.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 3.0" HPA003444 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA003444: AB_1080732" "unprognostic (2.51e-2)" "unprognostic (2.30e-4)" "unprognostic (4.92e-2)" "unprognostic (1.12e-1)" "unprognostic (2.80e-4)" "unprognostic (4.24e-4)" "unprognostic (3.44e-3)" "unprognostic (8.88e-4)" "unprognostic (2.65e-1)" "unprognostic (3.17e-1)" "unprognostic (3.38e-5)" "unprognostic (1.50e-1)" "unprognostic (1.09e-6)" "unprognostic (2.74e-1)" "unprognostic (4.75e-2)" "unprognostic (8.08e-2)" "unprognostic (8.33e-5)" 1.6 4.9 10.5 2.3 10.2 0.6 3.1 14.4 11.2 5.0 6.8 4.4 2.1 3.3 4.8 1.6 3.9 1.8 5.3 9.4 12.3 5.0 2.2 2.6 3.8 8.2 8.9 8.5 2.5 5.3 14.7 1.1 8.6 5.5 1.8 25.8 3.5 4.6 2.0 3.2 4.2 1.8 7.9 4.7 3.2 2.9 11.4 2.1 7.9 1.6 3.4 3.6 3.4 9.1 0.1 0.0 1.1 1.3 3.0 1.8 0.1 0.4 0.4 0.5 0.9 0.1 0.0 0.5 0.1 1.1 0.3 0.4 0.8 0.4 0.4 1.7 1.2 0.4 0.8 0.0 0.8 0.5 0.9 0.9 1.1 0.3 0.0 0.2 0.0 2.4 0.2 0.0 0.7 0.0 0.8 0.3 0.4 0.1 0.2 0.7 0.7 0.4 0.2 0.1 1.2 1.4 0.4 0.1 0.1 0.8 0.6 0.5 0.0 0.4 1.4 0.5 0.4 1.6 1.0 1.3 0.0 0.2 0.2 0.0 0.0 0.8 2.7 0.0 2.6 1.9 2.7 3.0 0.1 2.2 4.4 4.8 0.1 2.4 0.0 0.2 3.1 1.2 10.5 10.2 14.4 11.2 9.4 12.3 8.2 8.9 8.6 7.9 11.4 9.1 2.3 3.2 2.6 15.3 6.3 1.7 1.3 0.8 3.4 23.3 2.4 2.2 10.4 0.0 1.7 1.8 6.2 0.3 3.3 0.2 7.9 0.3 18.6 1.1 1.0 2.2 0.0 0.0 47.7 0.4 0.4 2.8 1.5 0.6 3.8 1.7 2.2 1.1 0.8 18.5 56.5 0.3 0.0 0.8 1.0 5.5 2.5 1.0 3.6 11.2 0.5 5.5 8.2 23.1 27.7 0.2 1.1 5.7 2.5 0.4 2.3 2.7 0.4 22.3 6.6 3.1 2.9 5.7 3.3 1.8 1.3 0.1 3.9 1.2 0.3 0.2 ZNF569 "FLJ32053, ZAP1, Zfp74" ENSG00000196437 "Zinc finger protein 569" Q5MCW4 19 37411155-37469275 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 137.7;Late spermatids: 41.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052994 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA052994: AB_2682007" "unprognostic (1.40e-1)" "unprognostic (3.37e-1)" "unprognostic (4.95e-2)" "unprognostic (2.18e-2)" "unprognostic (5.44e-2)" "unprognostic (4.79e-2)" "unprognostic (2.95e-2)" "unprognostic (4.00e-1)" "unprognostic (5.08e-2)" "unprognostic (6.50e-3)" "unprognostic (4.01e-3)" "unprognostic (9.41e-2)" "unprognostic (9.70e-2)" "unprognostic (3.04e-2)" "unprognostic (5.77e-2)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" 3.3 4.1 4.0 2.8 4.1 4.6 3.5 7.2 4.5 3.3 4.0 2.2 1.7 3.8 4.7 2.2 3.3 2.3 4.3 3.3 5.9 3.5 3.3 2.5 4.0 3.6 4.8 5.6 1.8 4.5 3.3 3.0 4.2 2.9 1.8 13.7 2.3 2.8 4.4 3.2 1.8 3.4 3.6 3.4 2.3 10.9 5.8 5.1 5.6 4.7 3.2 2.2 1.8 6.5 3.3 6.2 7.6 12.2 6.0 5.5 3.7 5.9 3.4 6.1 6.5 2.3 1.5 4.0 8.4 4.5 6.0 1.2 8.4 2.0 6.6 9.0 5.1 10.3 1.8 3.8 3.6 1.9 4.0 3.8 1.4 6.3 0.2 6.3 5.2 11.7 3.3 0.8 8.7 2.0 12.0 4.1 8.0 0.2 4.4 8.1 9.6 4.1 4.4 3.3 6.4 9.8 0.2 1.3 3.4 7.1 5.3 8.1 5.3 4.9 10.1 3.9 9.6 10.2 18.6 15.0 0.2 4.2 7.8 3.7 1.8 5.9 6.4 2.6 5.5 4.6 5.7 6.1 2.2 5.4 8.0 6.5 1.8 4.8 3.3 2.4 6.1 2.4 4.0 4.1 7.2 4.5 3.3 5.9 3.6 4.8 4.2 3.6 5.8 6.5 5.1 0.0 1.7 14.0 7.8 1.7 1.7 2.0 2.8 16.1 3.5 4.2 16.3 0.0 5.2 1.8 31.3 3.2 8.1 0.5 1.9 1.5 137.7 5.1 3.9 6.5 0.0 2.1 14.5 2.0 4.0 4.0 1.5 2.3 2.5 5.3 5.3 2.5 2.9 3.3 17.4 0.4 0.0 3.8 3.9 41.8 4.7 4.0 0.0 8.4 3.0 9.3 8.2 20.6 23.4 1.6 0.4 7.5 2.4 0.9 1.0 4.7 5.3 30.2 0.0 6.9 6.3 32.3 13.1 3.4 2.0 0.8 9.1 4.2 0.7 0.9 ZNF571 HSPC059 ENSG00000180479 "Zinc finger protein 571" Q7Z3V5 19 37554782-37594792 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 77.4" "Cell type enhanced" "Detected in many" "Early spermatids: 20.9;Oligodendrocytes: 23.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA054762 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA054762: " "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (3.92e-2)" "unprognostic (1.19e-1)" "unprognostic (5.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.19e-1)" "unprognostic (9.03e-4)" "unprognostic (5.77e-2)" "unprognostic (9.82e-2)" "unprognostic (1.22e-3)" "unprognostic (3.90e-2)" "unprognostic (2.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.62e-1)" "unprognostic (4.89e-2)" "unprognostic (2.71e-4)" 4.1 7.5 8.9 3.6 8.4 8.5 14.5 9.4 11.1 6.4 8.1 3.4 2.2 6.1 9.9 4.1 6.7 5.0 4.2 7.2 9.0 7.4 3.5 3.9 5.5 7.2 8.1 8.3 3.2 12.0 8.9 5.5 7.1 8.0 3.5 28.9 3.3 4.6 4.1 8.5 2.9 4.8 4.5 5.5 3.9 10.6 7.0 6.2 77.4 3.9 6.0 4.5 4.0 9.9 2.5 1.4 8.6 12.5 6.3 6.4 2.8 3.8 6.0 8.9 11.0 2.7 2.4 13.6 11.6 3.9 6.3 3.3 2.8 4.1 14.8 3.0 10.9 7.3 4.4 1.6 7.2 2.7 7.9 3.5 7.2 8.6 7.8 6.3 1.8 12.1 3.5 1.1 7.3 2.4 13.8 3.0 21.7 4.0 4.8 6.8 4.1 7.2 12.4 16.3 18.5 12.9 8.9 2.9 4.5 17.1 13.3 1.9 1.1 4.1 5.2 4.5 9.8 10.5 23.4 18.5 0.6 1.2 9.1 1.6 0.7 4.4 5.2 1.2 4.8 7.6 5.0 5.3 2.3 7.7 6.0 6.6 1.2 3.2 1.1 3.5 3.8 2.7 8.9 8.4 9.4 11.1 7.2 9.0 7.2 8.1 7.1 4.5 7.0 9.9 5.5 0.0 2.0 5.2 6.6 1.8 1.2 1.9 5.2 9.5 3.5 3.2 1.6 1.5 4.6 5.5 10.4 2.4 11.9 0.8 3.9 2.3 20.9 3.1 3.1 6.0 1.2 4.8 8.6 1.6 1.8 3.1 2.0 2.4 15.2 5.1 4.6 0.8 1.7 13.5 9.7 1.9 6.1 1.3 2.1 4.3 4.4 1.7 5.4 5.6 0.6 4.9 5.2 17.1 23.9 1.0 1.0 2.6 3.5 1.9 1.1 2.8 4.0 16.0 13.1 4.9 4.2 10.3 6.2 2.9 2.6 1.2 8.7 4.1 1.7 0.5 ZNF575 FLJ32567 ENSG00000176472 "Zinc finger protein 575" Q86XF7 19 43525497-43536130 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 18.9;Paneth cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 7.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051865 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA051865: AB_2681643" "unprognostic (1.77e-3)" "unprognostic (2.73e-2)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (8.56e-2)" "unprognostic (6.53e-4)" "unprognostic (1.23e-1)" "unprognostic (2.37e-1)" "unprognostic (2.36e-2)" "unprognostic (2.21e-1)" "unprognostic (3.87e-5)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (7.83e-2)" "unprognostic (2.75e-1)" 2.8 1.6 1.5 1.1 2.2 0.6 2.1 2.5 4.4 3.0 0.0 4.5 1.6 2.9 1.0 1.6 2.3 0.7 2.3 2.1 0.0 2.1 2.1 1.6 1.1 0.9 0.2 3.1 1.5 0.5 3.2 0.4 0.9 2.1 2.0 0.6 1.7 1.0 4.6 2.0 2.2 0.8 0.0 2.1 1.5 0.8 1.1 1.1 2.1 0.5 0.6 2.2 2.3 1.5 1.9 1.7 0.4 0.5 2.4 2.0 0.1 1.2 0.8 0.4 0.6 0.4 0.7 0.4 0.8 0.9 0.2 1.0 0.0 0.2 0.2 2.7 0.3 1.4 0.7 0.3 0.5 0.6 1.7 1.2 0.7 0.6 0.1 1.3 0.3 2.6 0.5 2.6 0.7 1.3 7.7 0.2 0.1 1.3 0.8 4.1 0.0 1.0 0.4 1.1 0.3 0.6 0.9 1.2 1.3 0.3 0.3 0.7 1.3 2.3 1.5 0.5 0.9 1.3 2.2 1.2 1.4 1.7 2.4 0.0 0.4 0.3 1.4 0.2 0.5 0.7 1.3 1.4 0.6 1.8 2.1 1.5 0.4 3.3 0.2 0.9 1.4 0.7 1.5 2.2 2.5 4.4 2.1 0.0 0.9 0.2 0.9 0.0 1.1 1.5 1.5 6.4 1.1 1.6 1.3 0.1 0.6 1.2 1.8 1.2 1.1 1.9 2.0 0.0 0.9 0.0 4.2 1.3 1.9 18.9 3.9 0.4 0.1 0.5 1.6 1.8 1.2 1.3 0.9 0.6 0.9 3.5 1.1 1.1 0.0 1.5 2.5 2.3 1.6 0.0 1.1 2.3 0.0 2.7 1.0 0.4 2.5 1.8 1.8 0.0 0.8 0.8 4.1 0.0 1.3 0.2 8.7 3.4 2.6 0.3 2.0 2.5 0.2 0.1 0.0 2.0 2.6 0.1 1.1 2.6 1.7 0.3 3.1 0.7 2.7 0.5 ZNF599 FLJ30663 ENSG00000153896 "Zinc finger protein 599" Q96NL3 19 34758073-34773229 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 33.2;Early spermatids: 81.4;Late spermatids: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014701 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA014701: AB_1859371" "unprognostic (3.52e-3)" "unprognostic (1.42e-3)" "unprognostic (1.99e-2)" "unprognostic (9.35e-3)" "unprognostic (9.20e-2)" "unprognostic (5.16e-3)" "unprognostic (3.95e-3)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (7.35e-3)" "unprognostic (1.77e-3)" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-2)" "unprognostic (8.12e-3)" 4.4 5.9 5.8 2.3 6.7 1.2 5.6 6.8 6.0 8.1 8.1 6.3 2.5 7.6 11.9 3.9 8.6 2.4 4.7 5.5 6.4 9.5 4.7 4.7 3.3 6.4 6.6 7.4 4.8 9.8 11.0 3.1 6.3 9.5 2.8 4.7 5.9 4.8 3.6 4.4 4.3 3.6 6.2 5.0 4.8 14.0 6.6 4.2 11.1 5.0 2.7 6.0 6.1 7.3 4.8 2.4 4.6 3.4 5.2 6.9 2.6 1.7 4.5 4.1 4.7 2.0 3.1 0.5 4.3 3.1 3.8 2.3 3.4 2.3 4.9 0.5 4.2 3.6 4.9 5.7 4.1 0.8 3.5 6.5 3.1 1.9 2.0 6.7 4.7 8.3 6.2 0.4 6.0 1.9 9.1 3.8 2.0 6.5 0.1 4.6 4.5 3.0 5.1 1.1 5.8 8.4 5.6 1.0 3.2 3.0 2.8 0.4 2.6 3.2 4.4 3.0 1.9 5.1 5.6 0.4 2.5 0.1 3.8 1.9 0.6 3.5 3.4 1.4 2.3 1.0 3.5 1.9 1.0 2.2 3.5 3.2 0.3 3.5 3.2 2.2 2.8 1.6 5.8 6.7 6.8 6.0 5.5 6.4 6.4 6.6 6.3 6.2 6.6 7.3 5.8 0.0 3.7 5.2 2.5 3.1 7.6 5.5 6.8 4.2 10.2 11.2 4.4 1.5 8.3 18.4 2.1 7.9 5.2 1.1 33.2 4.6 81.4 25.4 6.4 5.3 1.2 3.8 0.7 2.3 4.5 8.3 1.5 4.1 0.0 6.6 5.0 4.0 3.8 0.0 3.5 3.3 4.1 1.0 1.9 30.8 10.2 1.2 5.4 0.0 0.9 14.4 4.1 9.5 8.1 3.1 0.9 4.9 4.8 5.5 2.9 15.3 22.7 2.7 6.6 5.7 5.7 26.2 7.5 4.8 1.6 1.9 3.9 7.2 3.2 6.0 ZNF614 FLJ21941 ENSG00000142556 "Zinc finger protein 614" Q8N883 19 52012765-52030240 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Late spermatids: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021197 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA021197: AB_1859380" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (7.67e-3)" "unprognostic (2.68e-1)" "unprognostic (4.74e-3)" "unprognostic (5.07e-3)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.74e-2)" "unprognostic (1.66e-2)" "unprognostic (3.06e-2)" "unprognostic (1.57e-1)" "unprognostic (2.30e-1)" "unprognostic (7.15e-3)" 4.1 3.6 4.0 3.3 4.6 6.3 5.6 8.2 5.3 4.2 2.4 3.0 2.5 5.3 3.9 3.4 4.2 3.3 4.0 3.7 4.8 3.8 2.3 3.5 4.3 4.5 4.6 7.5 1.8 5.0 3.3 6.9 4.3 8.9 3.0 8.7 3.0 4.7 4.0 4.3 2.9 4.9 4.1 4.5 3.2 6.9 5.2 5.9 8.0 5.0 4.4 3.9 2.1 6.4 4.8 3.5 8.8 11.5 6.2 6.9 1.1 6.4 4.5 5.8 7.0 4.4 2.7 12.1 3.4 5.5 5.4 2.0 13.3 8.5 8.6 3.2 18.8 18.2 6.6 9.0 5.1 3.8 8.8 5.4 4.6 5.9 8.2 5.8 6.9 10.5 9.9 2.6 7.9 1.9 16.0 7.6 10.2 0.7 6.3 10.5 17.0 10.0 6.0 12.0 11.6 7.1 3.8 4.7 3.9 10.8 6.3 9.6 7.1 5.7 7.9 3.2 7.6 5.2 8.7 18.3 5.5 5.2 7.6 2.3 2.4 1.6 3.2 3.2 3.9 3.0 2.9 3.1 3.0 2.8 4.1 2.6 1.7 5.7 2.8 1.7 3.2 1.8 4.0 4.6 8.2 5.3 3.7 4.8 4.5 4.6 4.3 4.1 5.2 6.4 5.2 0.0 2.2 3.6 4.8 3.2 5.3 2.4 4.6 6.8 4.2 4.2 5.8 4.3 4.9 5.5 4.2 6.1 6.5 1.7 0.0 2.9 47.9 2.8 6.1 5.8 5.4 7.4 6.6 0.9 7.1 3.7 5.6 3.7 7.0 5.0 8.2 1.6 2.3 16.8 6.7 2.4 2.0 4.1 2.3 34.9 4.1 3.2 1.8 4.7 2.2 5.1 10.3 6.0 9.2 1.4 0.7 7.2 5.4 4.6 1.8 2.0 0.9 5.6 0.0 7.1 5.7 2.2 5.0 4.4 2.7 14.4 4.1 2.7 2.2 5.1 ZNF622 "MGC17552, MGC2485, ZPR9" ENSG00000173545 "Zinc finger protein 622" Q969S3 5 16451519-16465800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036514, HPA036515" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA036514: AB_2675167, HPA036515: AB_10672224" "unprognostic (6.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.00e-2)" "unprognostic (6.53e-2)" "unprognostic (8.24e-3)" "unprognostic (4.71e-3)" "unprognostic (1.06e-1)" "unprognostic (1.71e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (8.69e-2)" "unprognostic (5.93e-2)" "unprognostic (2.19e-1)" "unprognostic (7.42e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" 19.5 13.5 20.3 13.8 21.4 36.0 18.4 17.2 21.8 16.7 14.4 21.5 16.9 17.8 17.2 17.9 15.3 12.1 56.9 18.1 19.6 14.6 22.0 16.6 17.8 18.7 20.7 15.6 54.3 15.6 15.1 16.9 20.3 15.5 20.7 10.8 18.3 12.7 41.7 25.6 20.3 12.5 19.1 15.5 22.4 20.5 19.4 16.0 15.5 25.2 15.7 17.5 17.0 22.1 25.7 55.2 16.9 35.2 40.4 34.3 61.4 45.2 33.9 36.0 45.6 66.0 23.2 30.0 59.6 36.0 48.4 33.3 27.5 35.3 28.9 40.6 37.3 27.4 92.8 47.7 58.1 53.8 31.5 53.3 43.7 33.6 31.5 28.0 25.6 17.6 37.6 28.9 40.1 43.2 28.4 52.3 30.0 24.2 53.8 22.1 20.6 25.8 33.6 38.0 23.4 26.2 63.1 46.8 78.2 29.4 26.0 41.1 35.3 40.0 30.5 39.3 29.1 41.3 39.7 41.9 34.9 45.8 28.5 89.3 65.6 88.6 73.8 71.3 77.8 85.4 73.7 82.0 73.3 81.9 84.2 70.3 87.9 67.9 79.6 59.2 85.0 82.6 20.3 21.4 17.2 21.8 18.1 19.6 18.7 20.7 20.3 19.1 19.4 22.1 14.8 22.4 24.2 2.9 33.2 60.7 43.1 48.6 34.1 22.8 19.8 16.4 73.8 24.3 34.4 14.7 10.4 64.0 39.5 77.5 27.4 55.2 111.5 35.0 36.8 22.3 98.7 20.0 7.6 66.7 57.2 34.1 31.1 71.3 52.0 13.3 15.0 25.1 50.0 16.8 7.9 60.6 48.8 19.3 35.1 62.8 18.0 29.7 33.8 4.7 43.3 22.6 37.0 6.6 9.0 51.2 127.1 19.9 26.6 28.3 84.5 39.2 29.7 19.3 19.7 31.7 46.9 63.2 37.8 21.8 43.2 40.6 41.6 20.5 55.5 33.5 ZNF626 ENSG00000188171 "Zinc finger protein 626" Q68DY1 19 20619939-20661596 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/84: 19.8" HPA045631 Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Vesicles" Nucleoplasm "HPA045631: AB_2679397" "unprognostic (1.75e-1)" "unprognostic (4.38e-2)" "unprognostic (3.58e-2)" "unprognostic (1.04e-1)" "unprognostic (2.53e-2)" "unprognostic (2.18e-2)" "unprognostic (6.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-2)" "unprognostic (6.51e-3)" "unprognostic (1.92e-1)" "unprognostic (2.49e-1)" "unprognostic (5.10e-2)" "unprognostic (1.73e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (2.31e-1)" 7.4 8.9 3.0 5.4 4.7 3.8 16.1 4.8 4.5 8.4 4.8 3.7 1.6 11.2 7.8 6.3 12.2 9.3 10.0 3.0 3.8 11.0 5.7 5.2 12.2 2.5 3.4 25.9 7.2 21.4 3.6 7.3 2.7 11.0 3.2 7.5 7.0 9.7 4.6 9.3 2.4 9.4 3.1 7.0 8.0 5.0 3.8 8.6 23.7 5.9 9.7 14.8 4.1 5.8 0.1 0.0 5.9 0.4 6.8 8.7 0.3 6.5 0.6 9.1 7.9 0.1 0.1 0.5 3.0 8.3 10.7 1.1 0.0 0.2 11.6 0.1 0.2 0.0 0.2 2.3 12.1 0.1 0.0 16.6 2.6 5.5 2.8 0.1 4.3 0.1 4.1 0.6 9.6 0.1 0.4 1.1 12.0 0.0 2.9 5.7 4.1 2.1 8.4 6.4 1.6 10.6 0.1 0.7 6.0 10.6 13.7 0.1 0.1 4.2 0.2 16.4 0.5 9.0 19.8 8.6 0.1 0.1 0.5 0.9 1.1 6.3 7.2 1.1 6.8 8.4 7.6 8.2 3.2 10.5 7.0 6.3 11.2 9.8 4.8 4.2 3.8 3.8 3.0 4.7 4.8 4.5 3.0 3.8 2.5 3.4 2.7 3.1 3.8 5.8 14.0 3.2 8.2 26.4 18.5 9.4 13.7 4.2 10.2 11.1 18.2 18.8 9.8 12.8 6.7 27.6 10.4 17.5 11.1 1.4 31.3 8.7 1.3 19.3 15.0 11.6 2.4 1.7 29.3 9.5 24.9 13.9 6.1 20.8 7.0 19.7 17.2 7.4 11.0 13.5 27.6 1.3 6.1 4.7 9.8 1.7 18.6 5.1 5.4 15.9 2.9 16.2 19.6 37.7 43.0 9.1 0.4 15.4 3.9 17.2 0.1 30.8 12.3 9.5 13.1 11.4 11.9 10.1 16.2 6.1 12.6 43.4 12.3 39.8 0.8 15.5 ZNF646 KIAA0296 ENSG00000167395 "Zinc finger protein 646" O15015 16 31074422-31084196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.7" "Cell type enhanced" "Detected in many" "Early spermatids: 24.8;Spermatocytes: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042364, HPA066468" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA042364: AB_10794796, HPA066468: AB_2732746" "unprognostic (1.61e-2)" "unprognostic (2.18e-1)" "unprognostic (8.08e-2)" "unprognostic (1.18e-2)" "unprognostic (4.66e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.28e-6)" "unprognostic (3.23e-2)" "unprognostic (4.21e-2)" "unprognostic (6.96e-2)" "unprognostic (1.16e-2)" "unprognostic (9.83e-2)" "unprognostic (2.07e-2)" "unprognostic (2.65e-1)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.16e-1)" 5.6 4.1 4.4 6.7 4.9 9.2 5.0 6.9 5.9 5.8 1.6 5.0 6.4 6.5 2.5 5.2 5.5 3.5 4.8 3.7 2.9 4.9 4.3 4.7 7.1 6.2 4.7 6.2 5.6 4.4 5.0 4.0 4.9 5.4 2.8 1.6 6.2 4.0 7.9 8.0 6.4 3.2 3.5 8.0 5.5 25.7 5.8 8.6 5.1 3.7 5.1 5.4 4.9 6.3 7.8 15.8 10.2 8.0 7.1 5.5 13.7 8.3 8.8 9.8 9.0 11.6 7.1 15.0 13.0 7.1 6.5 10.2 8.5 9.2 3.7 17.2 8.1 11.1 15.6 9.7 7.4 14.4 16.7 7.1 8.1 10.6 6.0 7.6 5.9 12.5 18.2 8.5 7.5 12.2 16.0 9.9 13.8 3.5 8.1 25.5 20.2 15.3 3.1 7.3 14.7 14.9 9.5 10.0 4.9 4.4 8.4 12.5 12.1 12.3 7.0 8.2 7.8 14.2 14.1 14.9 11.2 15.5 9.8 9.8 4.5 13.2 5.1 4.2 2.6 3.9 2.4 2.1 4.6 4.4 2.7 3.0 25.1 4.8 2.8 6.6 2.6 2.1 4.4 4.9 6.9 5.9 3.7 2.9 6.2 4.7 4.9 3.5 5.8 6.3 4.7 3.2 1.3 3.6 4.2 3.3 1.0 2.6 2.8 3.6 3.4 3.4 1.7 1.5 2.2 1.8 4.2 1.9 6.6 6.6 1.9 4.1 24.8 3.0 3.7 3.4 6.0 2.1 2.2 3.5 2.1 2.5 5.6 4.9 1.3 5.1 1.8 1.9 4.9 1.7 2.1 3.4 4.1 4.7 2.8 6.6 2.8 6.4 0.0 7.5 3.7 3.6 4.1 2.0 3.1 4.4 7.6 4.5 2.3 2.4 5.8 2.2 2.7 1.1 0.0 3.5 2.3 16.2 7.0 2.9 4.0 2.5 4.9 2.8 3.7 1.9 ZNF654 "FLJ10997, FLJ21142" ENSG00000175105 "Zinc finger protein 654" 3 88059255-88144660 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036172, HPA036173, HPA049262, HPA077939" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA036172: AB_10672081, HPA036173: AB_2674987, HPA049262: , HPA077939: AB_2732364" "unprognostic (2.54e-2)" "unprognostic (2.28e-1)" "unprognostic (6.89e-3)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.29e-2)" "unprognostic (5.74e-2)" "unprognostic (3.45e-2)" "unprognostic (7.65e-2)" "unprognostic (2.02e-1)" "unprognostic (5.72e-3)" "prognostic unfavorable (9.97e-6)" "unprognostic (1.29e-2)" "unprognostic (2.92e-1)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (2.50e-2)" 5.0 3.7 2.6 4.1 2.7 8.1 5.5 4.9 3.3 5.1 1.8 4.4 4.5 4.6 4.7 5.6 3.4 4.8 3.4 2.4 3.2 4.8 7.0 4.5 6.1 2.8 3.1 6.4 4.1 4.3 1.2 5.0 3.3 5.5 4.2 11.7 4.6 4.1 3.0 6.5 4.8 4.1 3.2 4.9 4.7 6.0 2.7 7.6 5.9 4.9 5.7 5.1 2.3 3.9 7.2 3.0 5.0 6.9 9.9 8.6 4.6 9.3 8.4 6.1 8.4 4.4 4.3 11.3 6.2 7.4 4.4 4.7 5.3 8.6 11.8 7.0 3.0 7.0 3.9 3.2 7.5 8.0 7.6 8.4 7.4 6.7 7.8 12.1 8.1 6.6 4.9 9.0 13.6 5.3 8.0 6.5 2.7 5.7 4.8 5.7 3.4 5.4 5.4 9.0 3.7 3.3 6.8 5.2 17.0 6.0 7.3 5.7 9.5 13.6 8.7 51.8 6.6 10.1 7.6 7.9 10.8 7.5 8.6 9.7 1.2 1.8 1.7 1.2 2.0 1.1 1.8 2.4 1.5 1.7 2.2 1.5 1.7 4.0 1.0 0.7 1.4 1.0 2.6 2.7 4.9 3.3 2.4 3.2 2.8 3.1 3.3 3.2 2.7 3.9 18.2 9.6 13.1 10.1 12.8 22.4 10.1 7.9 9.1 14.0 17.4 10.2 11.8 5.7 10.8 5.5 12.5 4.8 14.5 11.9 1.9 7.6 1.4 9.4 16.0 12.4 5.3 5.2 11.7 5.3 4.2 11.7 5.1 12.2 15.8 14.5 8.9 14.0 6.3 16.8 11.3 7.1 10.2 12.3 19.5 1.5 7.5 14.8 8.8 7.5 10.9 9.9 9.2 9.0 13.3 8.4 8.2 12.4 9.2 12.0 9.0 6.0 10.7 14.3 6.6 13.9 11.5 12.1 10.4 11.4 18.6 8.2 14.0 9.0 7.8 14.4 ZNF668 FLJ13479 ENSG00000167394 "Zinc finger protein 668" Q96K58 16 31060843-31074240 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043048 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA043048: AB_10962503" "unprognostic (2.71e-2)" "unprognostic (4.95e-2)" "unprognostic (6.42e-2)" "unprognostic (1.48e-1)" "unprognostic (3.27e-1)" "unprognostic (7.20e-3)" "unprognostic (6.73e-5)" "unprognostic (4.03e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-1)" "unprognostic (7.71e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (1.72e-3)" "unprognostic (2.00e-1)" "unprognostic (2.23e-1)" "unprognostic (4.83e-3)" "unprognostic (7.25e-2)" 5.6 6.6 4.4 3.4 4.1 7.9 4.7 4.7 6.6 5.5 1.7 5.6 4.4 6.9 0.7 6.4 4.6 2.3 5.7 4.5 3.2 4.4 4.8 4.4 2.6 5.1 3.6 3.8 3.9 2.3 4.9 3.6 4.8 6.3 1.3 0.8 4.6 2.4 6.1 7.3 4.8 3.4 3.2 6.0 4.8 7.5 4.0 3.0 4.1 1.7 1.6 6.2 5.2 4.0 5.2 17.2 3.8 9.4 3.9 4.1 13.0 14.6 10.3 7.1 5.9 8.0 7.0 8.3 11.2 8.4 4.5 9.2 2.6 7.8 1.8 10.6 11.1 5.1 11.4 12.8 4.8 8.2 12.3 5.1 3.2 12.1 2.4 2.3 5.1 8.9 9.7 4.9 12.8 17.2 17.3 17.2 13.6 3.6 14.4 22.4 28.5 12.0 3.7 11.2 13.3 15.7 9.3 12.5 4.7 1.5 9.6 11.5 8.9 17.5 7.2 13.4 6.2 8.4 15.1 12.1 11.7 8.3 11.4 8.7 4.2 7.9 11.1 3.9 7.3 4.3 3.2 6.7 6.2 3.0 3.4 4.4 1.5 7.8 3.4 3.3 3.5 5.1 4.4 4.1 4.7 6.6 4.5 3.2 5.1 3.6 4.8 3.2 4.0 4.0 3.4 0.0 3.6 3.6 4.6 8.4 2.4 5.3 7.4 3.5 4.5 3.7 0.6 4.3 3.8 0.0 0.0 6.5 5.9 6.3 7.9 8.9 44.7 3.8 4.7 4.3 4.8 4.6 3.7 4.8 11.4 6.4 4.1 8.1 4.5 4.7 3.6 2.8 6.8 11.8 3.7 3.7 4.1 3.8 7.1 15.3 6.2 9.3 3.6 2.8 5.5 5.1 12.3 1.0 4.2 7.5 4.9 15.1 4.5 4.0 7.5 5.8 1.7 2.1 0.0 9.0 5.5 5.9 12.8 8.8 8.8 7.0 7.4 5.0 4.6 2.2 ZNF678 MGC42493 ENSG00000181450 "Zinc finger protein 678" Q5SXM1 1 227563543-227677443 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 38.2;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028507 Uncertain Approved Nucleoli,Mitochondria,Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli, Mitochondria, Cytosol" "HPA028507: AB_10603567" "unprognostic (1.76e-2)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (4.42e-3)" "unprognostic (3.92e-2)" "unprognostic (4.64e-2)" "unprognostic (1.59e-2)" "unprognostic (2.19e-2)" "unprognostic (2.50e-1)" "unprognostic (1.64e-1)" "unprognostic (3.54e-6)" "unprognostic (1.39e-1)" "unprognostic (4.18e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-4)" 2.5 3.1 2.2 3.0 3.3 3.4 3.7 3.6 2.8 3.6 1.1 2.9 2.3 3.8 2.4 2.1 3.1 3.1 1.9 2.3 4.3 2.6 2.2 3.2 4.4 3.1 2.8 4.0 3.3 2.3 1.5 4.2 2.8 4.0 4.1 5.7 2.7 2.4 1.5 1.4 2.1 2.4 2.3 3.6 3.3 3.9 3.4 4.4 5.4 2.7 4.0 2.1 2.3 5.6 2.5 4.0 13.6 15.5 1.6 3.7 8.3 3.3 3.2 4.8 4.9 3.3 2.9 9.7 8.3 1.5 2.5 4.6 8.3 2.2 7.6 4.2 15.8 4.5 2.9 2.0 3.0 8.0 12.0 3.3 3.8 2.8 6.0 3.5 4.5 10.9 12.4 15.1 5.2 2.0 11.3 2.8 12.1 3.6 6.3 8.4 8.9 3.9 3.4 7.7 5.8 11.2 4.8 5.6 2.3 6.6 7.9 9.2 3.3 5.9 5.5 5.2 6.6 4.8 11.8 10.5 2.3 1.4 6.2 5.4 0.6 0.8 1.3 0.1 1.6 3.7 1.3 0.8 1.2 2.6 1.2 1.7 0.1 1.4 0.4 1.8 1.7 0.8 2.2 3.3 3.6 2.8 2.3 4.3 3.1 2.8 2.8 2.3 3.4 5.6 10.9 3.2 7.3 21.2 7.8 2.3 4.0 2.9 2.2 12.2 5.5 2.9 4.2 4.3 4.5 3.7 4.2 2.1 8.2 6.8 1.9 4.0 0.9 4.6 6.0 6.5 9.6 10.3 11.7 5.2 2.4 6.5 7.1 4.8 3.8 9.4 5.3 3.0 1.8 1.7 17.2 4.8 4.1 3.1 3.7 0.6 7.5 3.3 0.0 17.8 3.3 4.7 5.2 38.2 44.7 3.3 7.3 2.6 5.8 5.4 1.3 1.4 5.5 7.3 0.0 12.3 4.9 7.6 10.5 3.1 0.6 1.4 5.8 4.2 3.8 3.8 ZNF688 ENSG00000229809 "Zinc finger protein 688" P0C7X2 16 30569672-30572734 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 180.3;Late spermatids: 576.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048922 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA048922: AB_2680557" "prognostic favorable (5.90e-4)" "prognostic favorable (7.74e-4)" "unprognostic (1.68e-1)" "prognostic favorable (4.58e-5)" "unprognostic (1.37e-1)" "unprognostic (1.76e-2)" "unprognostic (4.01e-1)" "prognostic favorable (3.24e-4)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "prognostic favorable (6.61e-4)" "unprognostic (7.75e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-2)" "unprognostic (2.48e-1)" "unprognostic (4.12e-2)" "unprognostic (4.03e-2)" 8.7 8.4 17.6 9.8 17.5 11.4 5.1 20.5 19.1 6.7 16.4 9.7 14.6 7.8 5.6 5.6 10.4 4.2 7.0 16.5 15.8 8.2 8.3 7.5 9.5 17.5 16.9 9.1 12.3 9.7 8.4 3.3 17.2 7.5 6.4 5.6 10.1 6.9 25.6 9.0 11.6 5.8 16.2 12.0 10.1 13.6 18.1 8.2 5.1 9.7 5.4 6.6 5.7 20.2 10.4 9.5 7.3 8.1 13.3 5.2 3.1 6.7 8.2 5.0 4.0 2.5 15.1 6.2 12.8 6.9 6.0 8.6 2.2 3.6 4.7 16.7 6.4 3.8 3.7 2.7 6.3 4.3 17.9 8.7 8.2 5.3 6.0 7.7 4.7 7.7 3.9 12.0 5.3 13.5 14.9 9.9 3.3 8.6 4.9 13.3 3.8 9.2 8.2 3.2 12.1 13.2 2.4 14.1 15.3 2.0 15.6 7.8 5.4 5.5 4.0 5.2 4.7 20.5 13.2 5.7 12.2 4.3 9.7 12.0 4.6 11.0 6.2 4.2 5.4 6.5 6.6 6.8 4.2 7.6 5.7 5.0 5.3 20.4 6.5 7.4 11.2 3.3 17.6 17.5 20.5 19.1 16.5 15.8 17.5 16.9 17.2 16.2 18.1 20.2 16.3 6.4 3.1 5.9 22.8 6.4 10.5 12.6 16.5 19.8 20.3 22.7 11.2 22.8 10.2 16.5 18.8 7.5 26.0 38.6 49.0 24.8 180.3 25.4 9.5 14.0 20.4 11.2 5.1 31.2 9.6 15.6 17.9 9.0 5.1 12.1 20.7 22.6 24.4 21.9 5.1 27.7 12.2 33.1 12.0 576.6 19.9 17.4 17.8 1.9 28.3 31.2 30.9 9.0 10.3 21.8 37.2 19.9 16.7 10.1 59.2 54.1 38.4 27.4 6.6 17.2 20.2 34.5 8.5 11.2 7.1 4.7 23.2 15.1 23.6 8.5 ZNF691 Zfp691 ENSG00000164011 "Zinc finger protein 691" Q5VV52 1 42846573-42852477 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062527 Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Vesicles" "HPA062527: AB_2684791" "unprognostic (4.34e-2)" "unprognostic (4.05e-2)" "unprognostic (1.09e-1)" "unprognostic (4.32e-2)" "unprognostic (4.86e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (7.33e-6)" "unprognostic (1.40e-3)" "unprognostic (2.65e-3)" "unprognostic (5.12e-2)" "prognostic favorable (6.25e-5)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" 5.9 9.8 11.0 8.8 11.9 2.3 11.2 11.4 14.4 11.1 11.7 9.7 6.5 9.9 15.1 6.1 9.9 6.1 9.1 10.6 11.7 11.6 18.2 7.3 13.0 12.3 11.5 13.0 8.9 13.6 9.2 9.3 12.1 10.5 7.2 11.3 9.8 11.0 8.0 9.5 7.5 9.5 11.1 12.1 7.7 6.7 12.3 15.5 12.1 9.9 12.7 9.0 7.0 12.6 6.6 9.1 18.1 15.0 16.0 12.2 2.3 7.7 9.3 12.4 12.3 6.5 9.5 16.2 11.8 7.3 6.2 11.5 17.6 10.3 10.6 29.3 17.8 17.0 27.2 11.7 11.9 6.6 3.5 10.6 12.3 15.6 12.7 15.1 12.8 15.8 16.8 6.9 12.3 5.3 19.8 8.7 27.1 7.2 6.8 13.2 22.8 11.2 11.6 6.2 13.0 12.9 7.9 14.2 13.3 26.9 7.8 22.2 6.7 12.3 12.8 7.0 8.6 16.5 14.0 4.7 8.6 7.8 10.6 24.5 12.7 19.2 12.9 11.5 17.0 17.2 17.4 17.8 12.7 23.4 16.8 16.6 6.9 21.3 12.4 14.1 23.1 14.8 11.0 11.9 11.4 14.4 10.6 11.7 12.3 11.5 12.1 11.1 12.3 12.6 3.6 6.4 2.7 2.6 4.1 1.8 2.7 4.1 2.8 2.5 4.5 5.6 6.5 10.0 2.7 5.5 4.2 6.5 1.4 1.4 7.9 5.5 6.8 1.2 3.3 5.1 3.0 3.0 2.0 3.8 5.3 4.3 3.1 1.2 5.1 5.3 5.0 7.6 6.8 1.7 2.3 2.8 6.1 4.1 1.2 3.2 7.2 3.0 1.8 3.7 3.1 6.4 5.2 5.0 4.1 2.3 3.2 7.2 2.3 3.2 3.5 9.6 3.2 4.2 0.0 2.3 3.2 10.4 7.4 3.1 0.9 3.3 3.3 5.3 2.4 1.2 ZNF717 "X17, ZNF838" ENSG00000227124 "Zinc finger protein 717" 3 75678660-75785583 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 35.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 47.7" HPA044549 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA044549: AB_10964630" "unprognostic (2.49e-1)" "unprognostic (4.44e-2)" "unprognostic (1.52e-1)" "unprognostic (2.49e-2)" "unprognostic (2.61e-1)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (3.80e-2)" "unprognostic (3.20e-1)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" "unprognostic (1.45e-2)" "unprognostic (3.60e-6)" "unprognostic (3.88e-2)" "unprognostic (2.08e-2)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" 5.1 5.7 7.6 3.3 9.6 2.8 7.3 7.7 9.5 5.7 4.4 5.1 5.7 5.9 15.4 5.4 7.2 4.5 5.9 7.2 8.1 9.9 7.9 4.6 4.8 9.0 8.5 7.9 8.9 8.3 9.3 5.0 9.2 6.7 6.6 7.8 7.2 4.7 4.2 9.9 5.2 4.2 8.5 7.1 7.4 8.2 8.7 4.7 9.3 4.4 7.1 5.8 5.4 12.3 11.4 5.8 5.2 3.6 6.1 8.5 3.9 3.5 5.2 5.1 5.9 9.4 9.8 5.2 4.6 6.0 5.0 6.3 6.8 4.5 4.2 0.5 7.0 8.6 9.4 0.9 15.9 0.5 8.6 10.4 4.8 12.8 17.4 4.3 0.7 0.5 47.7 11.6 5.7 1.8 0.6 17.1 5.2 8.9 6.3 7.7 4.5 27.0 7.6 3.8 4.2 17.4 3.5 6.6 14.6 5.1 16.8 4.6 1.6 9.3 10.9 6.4 1.4 12.0 19.9 5.2 4.7 1.3 6.0 1.3 2.6 5.1 2.1 3.8 1.2 5.1 3.3 2.0 2.7 6.1 6.3 3.7 0.7 3.0 3.8 4.1 1.1 2.0 7.6 9.6 7.7 9.5 7.2 8.1 9.0 8.5 9.2 8.5 8.7 12.3 6.6 3.2 3.1 28.1 6.0 3.2 4.2 3.4 5.2 8.5 9.1 8.3 5.6 8.6 4.2 7.3 2.1 5.2 5.8 2.2 11.7 4.6 5.0 3.4 4.8 5.1 5.3 7.4 21.7 4.4 1.8 5.7 4.6 2.6 8.9 11.4 7.9 8.2 7.3 10.1 27.2 7.0 4.1 5.7 4.1 2.1 2.5 4.5 1.8 16.9 5.0 5.2 5.2 25.6 35.4 3.9 2.0 3.0 0.7 5.1 6.3 17.5 6.3 8.1 0.0 5.1 5.3 11.1 8.6 7.0 4.4 3.4 3.1 7.9 5.0 3.9 ZNF720 ENSG00000197302 "Zinc finger protein 720" Q7Z2F6 16 31713229-31794869 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA041570 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Nucleoplasm, Plasma membrane" "HPA041570: AB_10795126" "unprognostic (5.52e-2)" "unprognostic (2.30e-1)" "unprognostic (1.84e-1)" "unprognostic (8.30e-2)" "unprognostic (2.58e-1)" "unprognostic (2.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.82e-3)" "unprognostic (8.72e-2)" "unprognostic (5.94e-2)" "unprognostic (1.54e-1)" "unprognostic (8.91e-3)" "unprognostic (5.47e-3)" "unprognostic (3.70e-2)" "unprognostic (9.62e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-2)" 6.0 6.9 5.9 6.8 5.7 6.5 7.2 10.8 6.4 5.1 5.9 7.3 4.1 6.2 9.4 7.8 7.0 5.9 4.6 5.7 6.3 8.7 6.7 6.1 11.0 6.8 7.3 4.4 7.2 7.2 7.3 9.2 7.7 7.9 7.9 6.1 5.8 7.0 6.3 10.0 5.3 6.1 6.6 8.2 8.3 8.2 6.5 7.4 7.7 4.4 10.8 6.2 5.7 6.3 15.1 10.5 12.6 10.7 10.9 16.5 12.4 15.9 10.1 7.6 10.1 7.9 15.8 7.3 27.2 5.3 11.2 10.2 12.7 6.2 11.3 32.7 6.6 4.1 5.7 21.8 16.4 8.8 21.6 11.1 16.7 5.3 7.3 15.1 14.3 17.4 13.8 9.4 8.3 24.5 8.9 11.6 12.5 10.4 8.2 17.0 5.7 11.5 8.5 9.4 5.6 8.6 15.9 6.8 15.4 19.9 13.5 17.3 9.5 5.5 4.3 11.1 4.9 15.5 18.3 21.0 4.9 13.3 8.8 21.2 6.7 33.7 18.6 7.6 14.3 19.9 13.0 17.2 7.4 20.3 12.2 15.1 8.8 20.2 8.5 12.9 18.1 6.8 5.9 5.7 10.8 6.4 5.7 6.3 6.8 7.3 7.7 6.6 6.5 6.3 19.4 16.0 21.0 25.8 19.8 9.1 16.9 23.4 6.8 25.6 15.0 18.4 12.2 5.7 19.4 5.5 6.2 35.4 24.5 10.3 23.5 16.9 7.3 20.6 19.2 21.5 17.4 9.9 32.0 13.5 12.3 16.4 15.3 20.1 21.5 25.8 15.7 10.6 16.8 23.5 28.7 13.5 22.4 9.5 14.5 4.1 13.4 13.0 10.6 24.4 14.5 18.1 40.2 40.2 31.0 19.0 10.8 18.4 13.9 28.4 7.2 15.7 19.5 9.8 32.9 21.3 15.3 28.2 19.3 9.4 11.5 71.0 20.9 25.7 10.6 24.3 ZNF786 DKFZp762I137 ENSG00000197362 "Zinc finger protein 786" Q8N393 7 149069641-149090782 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.8;Horizontal cells: 18.5;Inhibitory neurons: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021518, HPA053459" Uncertain Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA021518: AB_2670734, HPA053459: AB_2682159" "unprognostic (3.13e-2)" "unprognostic (2.72e-1)" "unprognostic (5.61e-2)" "unprognostic (5.39e-2)" "unprognostic (1.87e-1)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.62e-2)" "unprognostic (1.09e-3)" "unprognostic (8.85e-2)" "prognostic favorable (2.01e-4)" "unprognostic (3.97e-2)" "unprognostic (1.39e-2)" "unprognostic (8.86e-3)" "unprognostic (1.31e-1)" "unprognostic (3.44e-1)" "unprognostic (1.47e-2)" 2.0 2.2 2.9 2.8 2.6 1.5 2.6 3.9 4.3 3.5 1.1 3.1 2.0 3.3 2.4 3.8 3.1 2.0 2.0 2.8 2.6 2.9 3.1 1.9 3.8 1.6 1.7 3.2 2.6 2.3 3.8 1.6 1.5 3.7 1.4 1.9 3.0 2.2 2.0 5.6 3.1 1.9 0.9 3.9 2.3 1.6 2.8 3.5 2.9 2.3 2.8 3.3 3.5 2.8 4.5 8.1 6.1 10.4 3.7 1.5 8.7 2.7 2.8 2.9 2.3 4.3 4.0 6.3 6.3 1.9 5.1 5.0 3.8 3.6 1.9 6.9 5.9 3.2 5.1 5.4 3.1 6.3 4.1 2.2 4.0 3.6 2.6 3.0 2.7 4.5 5.6 3.5 2.7 13.9 10.7 10.5 11.4 4.1 6.0 7.7 3.0 4.1 2.4 6.1 7.3 11.5 6.6 6.1 5.0 3.8 3.9 3.0 3.6 3.4 2.0 6.0 3.9 12.7 10.0 3.5 5.7 3.9 3.8 1.8 3.4 2.9 10.4 4.7 8.8 6.4 7.5 9.4 4.3 5.9 9.7 8.3 1.1 8.5 4.0 3.7 5.0 5.0 2.9 2.6 3.9 4.3 2.8 2.6 1.6 1.7 1.5 0.9 2.8 2.8 2.4 0.0 1.1 3.6 3.5 2.7 2.6 4.2 2.8 10.1 2.3 1.3 2.7 1.5 1.6 3.7 2.1 2.4 5.9 2.0 3.9 4.1 0.4 0.9 2.1 3.1 4.8 0.8 18.8 1.5 2.5 2.6 6.6 1.1 4.5 4.5 1.8 2.4 2.2 18.5 15.8 1.6 2.0 1.9 2.6 0.4 3.1 2.1 0.0 3.7 3.6 2.8 13.4 7.1 5.4 1.8 3.3 4.1 2.9 1.4 1.7 2.5 2.3 6.0 0.0 3.3 2.5 4.9 8.3 2.3 1.7 1.9 6.0 1.8 2.7 1.7 ZNF787 ENSG00000142409 "Zinc finger protein 787" Q6DD87 19 56087366-56121295 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 110.5;Endometrial ciliated cells: 87.6;Rod photoreceptor cells: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 102.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035140 Supported Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli, Mitochondria" "HPA035140: AB_10602358" "unprognostic (1.97e-2)" "unprognostic (5.86e-2)" "unprognostic (8.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.26e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-2)" "unprognostic (1.86e-1)" "unprognostic (1.10e-1)" "unprognostic (1.96e-3)" 18.3 24.4 13.4 10.2 13.9 27.0 16.6 12.7 15.4 18.2 11.1 24.0 15.7 19.9 3.9 20.8 22.3 3.0 26.9 12.1 11.4 17.6 43.9 17.9 7.3 15.2 13.1 16.1 34.1 5.9 15.9 4.4 12.6 21.2 4.7 7.6 19.0 7.7 42.2 18.0 19.9 4.0 11.9 27.7 23.2 16.1 15.4 5.6 16.5 9.7 4.4 20.8 16.6 13.8 29.2 28.1 9.0 18.9 2.5 5.6 23.3 14.7 5.7 9.8 11.1 16.7 17.6 20.7 1.0 6.2 8.8 22.7 5.7 11.9 4.4 27.5 102.6 32.9 14.6 25.6 14.1 31.8 27.8 7.4 11.6 8.2 14.2 6.1 7.4 11.6 39.9 22.5 5.8 18.2 19.8 40.0 28.4 26.7 52.3 24.6 13.1 26.7 10.2 19.1 34.2 33.3 15.6 30.2 29.4 5.0 18.6 44.5 16.0 36.8 26.6 15.7 41.2 47.4 37.4 20.3 21.4 21.0 17.6 0.6 0.8 1.1 0.4 0.6 0.6 1.0 0.3 0.3 0.8 1.4 0.5 0.2 1.8 0.5 0.6 2.2 0.5 0.3 13.4 13.9 12.7 15.4 12.1 11.4 15.2 13.1 12.6 11.9 15.4 13.8 29.5 12.8 2.7 5.5 11.2 6.1 11.5 5.0 7.4 52.1 19.2 16.9 12.0 11.5 5.5 11.0 110.5 3.3 20.0 29.7 1.9 6.6 2.0 87.6 17.2 16.2 9.1 4.0 5.1 16.7 4.6 10.1 8.6 48.2 5.7 23.2 11.7 33.4 8.9 35.3 4.2 19.8 8.2 11.0 7.8 3.4 5.0 16.4 1.8 6.5 8.9 44.5 7.2 4.5 6.1 13.1 19.5 4.5 7.1 11.3 12.8 5.8 4.0 71.3 6.6 16.0 13.0 3.8 12.1 4.8 7.2 1.9 9.2 55.8 20.6 12.4 ZNF79 pT7 ENSG00000196152 "Zinc finger protein 79" Q15937 9 127424374-127445372 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 5.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028977 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA028977: AB_10602359" "unprognostic (4.56e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "prognostic favorable (6.83e-5)" "unprognostic (2.84e-2)" "unprognostic (2.45e-2)" "unprognostic (2.11e-1)" "prognostic favorable (5.96e-4)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "prognostic favorable (5.42e-5)" "unprognostic (4.53e-3)" "prognostic favorable (6.04e-7)" "unprognostic (6.09e-3)" "unprognostic (5.01e-1)" "unprognostic (5.23e-2)" "unprognostic (1.32e-1)" 2.6 3.6 2.1 3.3 2.7 3.4 3.6 5.6 2.5 3.1 2.6 3.6 2.6 3.5 4.4 2.9 4.0 2.0 3.2 2.0 2.7 2.9 3.3 2.9 4.1 2.8 2.3 3.8 2.9 4.9 2.6 3.0 2.2 3.5 3.5 3.1 3.4 3.4 4.7 3.6 2.8 3.7 1.6 3.7 3.0 6.2 2.4 5.5 3.8 5.2 4.7 4.3 2.2 2.9 2.5 5.0 6.5 3.9 7.1 4.2 18.2 6.1 7.4 7.2 8.2 5.3 2.3 5.4 2.4 4.6 9.5 7.7 4.9 7.5 5.7 5.4 3.2 3.7 8.4 6.0 8.4 8.9 5.7 4.2 8.3 8.9 7.2 4.6 7.5 6.1 6.4 7.9 6.9 5.5 7.0 3.3 5.2 6.2 6.4 5.7 9.0 7.7 3.1 3.6 7.4 5.0 11.7 5.9 3.5 5.6 7.9 5.0 5.3 4.6 4.2 4.6 4.8 10.5 24.1 6.8 5.9 2.7 7.8 2.2 3.3 5.1 6.0 4.1 6.7 5.1 3.9 7.6 4.7 5.8 5.2 5.7 4.5 7.2 2.8 4.9 5.5 3.6 2.1 2.7 5.6 2.5 2.0 2.7 2.8 2.3 2.2 1.6 2.4 2.9 0.8 0.0 0.5 2.6 2.4 1.5 1.2 0.8 1.8 0.8 1.0 0.9 2.5 2.8 1.7 0.0 0.0 2.0 0.9 0.9 1.9 2.0 4.5 0.4 1.9 1.1 0.0 4.8 3.1 0.6 0.6 1.2 2.6 0.5 0.0 1.1 1.1 1.2 2.1 1.7 3.2 0.5 0.0 0.8 1.2 4.7 0.6 0.6 0.0 1.0 0.1 0.9 2.1 4.0 2.9 0.5 0.3 1.9 3.0 0.7 0.9 1.0 0.7 1.2 0.0 0.4 1.3 5.8 1.6 2.3 1.0 2.6 1.5 1.3 1.1 0.9 ZNF793 ENSG00000188227 "Zinc finger protein 793" Q6ZN11 19 37506939-37548762 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 31.3;Early spermatids: 39.6;Horizontal cells: 48.8;Rod photoreceptor cells: 33.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 11.6;RT4: 10.0;U-266/70: 18.4;U-266/84: 12.7" "Low region specificity" "Detected in all" HPA034781 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA034781: AB_10602784" "unprognostic (4.80e-2)" "unprognostic (4.70e-2)" "unprognostic (3.26e-1)" "unprognostic (7.13e-2)" "unprognostic (4.08e-2)" "unprognostic (5.72e-2)" "unprognostic (1.05e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-1)" "unprognostic (2.69e-3)" "unprognostic (4.16e-3)" "unprognostic (1.03e-4)" "unprognostic (4.94e-3)" "unprognostic (1.38e-1)" "unprognostic (4.62e-1)" "unprognostic (1.24e-2)" "unprognostic (8.12e-3)" 1.8 4.4 6.1 2.4 5.7 1.2 3.6 10.0 5.9 4.9 4.3 3.7 1.8 5.3 3.8 3.3 4.6 2.5 4.2 5.5 5.5 5.3 0.8 2.1 3.7 4.4 4.4 8.1 2.5 6.0 9.2 2.7 4.2 4.6 3.3 14.7 2.8 3.2 2.4 6.4 2.5 3.3 3.2 3.6 3.0 9.0 5.3 2.8 6.5 2.3 2.8 3.7 4.5 6.0 0.1 0.2 4.5 11.6 0.9 0.9 0.3 3.7 0.2 0.7 0.4 0.2 1.5 3.4 5.6 1.9 1.0 0.5 0.3 2.9 0.3 0.8 4.2 0.4 0.4 0.3 2.4 0.2 2.9 3.5 2.2 0.7 0.1 0.3 0.1 0.4 0.1 0.5 0.5 3.2 0.4 0.4 7.3 0.0 0.2 0.1 0.1 0.8 3.3 10.0 3.4 6.8 0.1 0.1 0.0 8.2 6.7 0.3 0.4 0.1 1.8 0.2 3.5 18.4 12.7 0.2 0.0 0.2 0.6 4.0 0.6 0.5 0.6 0.2 0.9 0.9 1.1 1.0 0.4 1.4 0.7 0.9 1.6 1.6 0.2 0.9 1.0 0.7 6.1 5.7 10.0 5.9 5.5 5.5 4.4 4.4 4.2 3.2 5.3 6.0 6.5 3.2 5.8 24.2 4.0 3.3 3.8 2.6 6.2 29.1 5.0 5.8 9.7 7.2 5.0 12.9 31.3 5.5 2.9 1.7 3.9 3.6 39.6 5.0 8.7 7.0 9.0 2.1 14.9 1.5 4.1 4.6 1.1 3.9 2.5 21.5 6.4 0.5 0.9 48.8 16.3 2.9 0.0 0.3 3.4 11.2 5.0 0.9 0.0 2.8 1.5 13.6 8.2 19.6 16.7 2.0 1.0 10.1 1.1 2.8 1.0 2.7 5.7 33.6 0.0 8.7 5.3 6.0 6.9 4.0 3.3 1.9 4.0 12.7 3.7 1.9 ZNF80 pT17 ENSG00000174255 "Zinc finger protein 80" P51504 3 114234631-114237578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 3.1" "Cell type enhanced" "Detected in some" "dendritic cells: 3.2;granulocytes: 1.3;NK-cells: 2.1;Plasma cells: 1.4;T-cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Not detected" "Not detected" HPA065484 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA065484: AB_2685496" "unprognostic (6.27e-3)" "unprognostic (3.00e-2)" "unprognostic (4.42e-2)" "unprognostic (1.26e-1)" "unprognostic (4.52e-2)" "unprognostic (9.68e-5)" "unprognostic (5.36e-1)" "unprognostic (6.52e-3)" "unprognostic (2.80e-2)" "unprognostic (1.27e-2)" "unprognostic (6.25e-2)" "unprognostic (1.49e-1)" "unprognostic (6.69e-12)" "unprognostic (1.85e-1)" "unprognostic (3.10e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-2)" 0.1 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.7 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.7 0.0 0.4 0.0 5.2 0.1 0.1 0.0 ZNF800 ENSG00000048405 "Zinc finger protein 800" Q2TB10 7 127346790-127431924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 74.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023090, HPA052194" Approved Supported "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoli, Nucleoli rim" Cytosol "HPA023090: AB_1859457, HPA052194: AB_2681757" "unprognostic (2.93e-2)" "unprognostic (1.10e-1)" "unprognostic (2.27e-1)" "unprognostic (3.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-2)" "unprognostic (6.19e-2)" "unprognostic (2.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (8.99e-2)" "unprognostic (7.04e-2)" "unprognostic (1.32e-1)" "unprognostic (1.08e-1)" "unprognostic (2.53e-2)" "unprognostic (8.96e-3)" 10.7 7.2 5.7 11.6 7.3 74.6 12.0 20.2 5.0 8.4 1.4 10.8 10.4 9.6 7.9 12.5 7.8 11.3 6.0 2.9 4.4 8.2 14.7 10.2 16.6 5.4 6.3 10.3 12.5 11.3 3.5 9.2 5.9 9.3 10.1 9.9 8.2 7.7 5.7 10.6 10.7 9.5 5.9 13.2 11.4 20.6 6.3 13.2 11.0 7.2 14.3 10.5 5.5 7.9 16.0 8.4 9.5 16.5 13.5 17.3 9.2 14.9 17.5 15.1 14.6 7.8 15.0 27.1 9.0 14.6 16.3 11.1 15.7 15.6 20.9 23.9 9.5 17.7 8.5 7.1 16.9 24.2 32.3 15.4 14.9 16.2 22.0 12.5 16.5 16.3 22.3 27.0 16.9 12.4 26.5 17.2 7.9 14.5 10.8 16.7 13.3 18.0 11.0 19.8 13.6 13.9 14.8 58.7 19.8 12.9 7.0 16.3 18.0 25.0 8.0 17.2 18.1 31.7 15.2 39.0 18.8 21.5 21.8 22.1 8.7 13.6 16.1 8.0 16.3 15.4 11.8 16.5 9.0 17.3 19.2 21.0 7.5 25.0 9.0 15.3 18.6 8.0 5.7 7.3 20.2 5.0 2.9 4.4 5.4 6.3 5.9 5.9 6.3 7.9 49.0 38.5 23.5 27.7 65.1 44.7 51.7 14.7 52.3 29.0 28.3 20.6 16.8 11.5 20.1 12.9 22.9 12.0 70.5 30.2 11.7 24.1 44.8 22.2 30.8 37.2 16.2 52.0 46.4 19.2 14.0 32.0 40.2 26.3 29.2 26.3 26.7 17.5 14.4 77.4 35.5 29.3 8.2 25.3 34.1 11.3 27.1 41.7 28.4 45.9 37.9 17.5 79.3 41.7 71.8 24.5 22.0 31.6 57.8 48.3 26.8 13.3 18.3 27.9 26.3 54.9 30.1 111.9 39.9 44.4 47.9 22.0 65.5 30.1 25.5 68.5 ZNF860 ENSG00000197385 "Zinc finger protein 860" A6NHJ4 3 31981750-31991723 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "B-cells: 14.0;Extravillous trophoblasts: 3.8;Respiratory ciliated cells: 4.3;Syncytiotrophoblasts: 4.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 7.0;naive B-cell: 5.2" "Lineage enriched" "Detected in single" 56 "B-cells: 7.0" "Cell line enriched" "Detected in many" 4 "BEWO: 44.8" HPA063386 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063386: AB_2684999" "unprognostic (1.19e-1)" "unprognostic (2.46e-2)" "unprognostic (2.88e-1)" "unprognostic (1.64e-2)" "unprognostic (1.51e-1)" "unprognostic (8.01e-2)" "unprognostic (1.23e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (1.51e-2)" "unprognostic (6.38e-2)" "unprognostic (1.30e-4)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.74e-2)" "unprognostic (3.75e-3)" 0.3 0.2 0.2 1.4 0.2 0.1 1.4 0.0 0.2 1.5 0.5 0.6 0.2 0.9 2.3 1.7 1.0 0.6 0.2 0.4 0.3 1.0 0.0 0.7 3.1 0.1 0.6 0.6 0.1 0.0 1.4 1.3 0.3 2.8 0.8 0.7 1.4 1.2 0.1 1.2 1.2 0.7 0.0 1.6 0.6 1.0 0.3 0.4 0.9 0.2 4.2 1.1 0.8 0.1 3.0 0.9 0.0 2.3 0.0 0.1 44.8 0.2 0.1 0.2 0.3 3.0 3.5 3.3 3.3 0.0 1.4 2.8 1.0 4.5 0.3 0.0 0.4 0.0 4.4 1.5 0.0 0.0 0.0 0.2 2.0 0.3 8.6 0.3 0.8 0.0 0.0 0.0 0.4 2.6 0.0 0.0 1.2 8.1 4.7 0.0 0.0 0.1 10.2 1.2 0.2 0.0 0.6 5.3 0.0 2.1 4.0 0.0 1.7 0.3 3.5 0.0 0.3 0.0 0.0 5.2 0.4 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.3 0.1 0.6 0.3 0.0 0.3 0.1 0.5 0.0 0.0 0.0 14.0 0.9 0.5 0.7 0.6 0.6 1.9 0.8 0.6 0.0 3.1 0.0 0.0 1.7 0.1 0.2 0.0 0.1 0.1 1.2 0.7 1.1 3.5 0.0 1.6 0.5 3.8 0.7 1.5 1.6 0.0 0.0 0.4 0.0 0.3 0.0 1.7 0.5 2.0 0.0 0.5 0.3 0.6 0.3 0.0 1.0 0.0 3.0 0.0 0.0 0.0 0.3 0.2 0.4 0.7 0.8 0.5 1.2 4.3 0.0 0.0 0.2 0.7 0.1 0.2 2.4 0.3 4.2 0.4 0.0 0.5 0.6 ZNF880 ENSG00000221923 "Zinc finger protein 880" Q6PDB4 19 52369917-52385795 "Predicted intracellular proteins, Transcription factors" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 38.9" HPA077316 Approved "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "HPA077316: AB_2686833" "unprognostic (2.66e-3)" "unprognostic (2.19e-2)" "unprognostic (2.55e-1)" "unprognostic (3.99e-2)" "unprognostic (7.72e-2)" "unprognostic (1.54e-2)" "unprognostic (7.61e-2)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (3.94e-2)" "unprognostic (2.52e-1)" "prognostic favorable (4.33e-8)" "unprognostic (4.14e-2)" "unprognostic (4.99e-1)" "unprognostic (1.77e-1)" "unprognostic (5.60e-3)" 12.5 11.0 8.6 10.9 10.4 17.7 13.5 23.7 10.6 11.9 7.0 11.6 5.7 13.1 11.2 6.3 12.1 10.7 17.5 8.7 9.2 15.1 3.6 11.2 14.7 11.2 11.2 18.4 7.2 5.3 10.4 10.0 12.0 17.1 8.8 16.0 10.8 13.0 7.1 11.2 10.0 11.9 9.4 14.4 9.5 9.9 11.4 15.3 18.1 7.9 14.3 13.5 8.8 12.7 0.3 1.6 19.1 16.0 10.8 29.1 21.9 13.5 13.9 9.2 17.7 0.4 9.1 0.3 4.8 22.2 19.1 3.2 0.1 12.5 14.5 0.3 24.2 0.6 1.0 0.0 12.7 0.5 16.7 23.1 15.6 16.7 0.0 1.1 14.7 1.7 1.7 0.7 18.4 1.3 2.0 1.2 27.6 0.0 3.3 1.4 38.9 1.4 25.8 20.8 14.9 18.8 0.1 4.0 5.9 35.2 0.7 4.3 11.8 0.6 0.4 4.2 12.7 0.8 8.0 0.6 0.4 0.4 26.8 80.3 12.9 31.9 25.1 12.9 32.4 50.3 31.8 27.2 20.9 53.4 37.9 33.0 5.2 26.2 15.2 41.2 37.2 17.5 8.6 10.4 23.7 10.6 8.7 9.2 11.2 11.2 12.0 9.4 11.4 12.7 13.3 12.8 3.9 4.2 15.2 5.9 22.6 22.6 10.8 15.9 7.2 9.7 13.1 4.3 20.4 20.2 12.5 9.9 12.4 2.2 29.4 18.8 12.8 19.2 10.6 10.8 0.0 5.9 3.5 14.8 14.8 11.9 5.6 13.5 10.1 6.0 9.3 1.5 7.0 23.5 4.2 6.2 18.3 4.9 9.8 5.3 13.7 8.2 8.8 1.9 13.9 12.1 32.0 4.5 5.8 20.8 7.9 6.4 2.8 23.3 2.3 8.4 11.3 16.7 19.7 12.3 14.0 4.6 10.1 4.3 7.1 14.4 13.5 5.2 4.0 23.5 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284597-30367689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved Uncertain "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center" "HPA072244: AB_2732197" "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favorable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favorable (8.71e-4)" "unprognostic (8.67e-2)" 7.4 6.5 4.8 11.5 5.3 13.0 9.6 5.5 4.2 5.1 14.5 18.9 13.2 8.4 10.7 10.4 4.4 9.4 5.1 4.3 4.0 22.0 21.5 7.4 15.3 7.4 6.6 3.7 10.3 9.1 5.0 9.3 6.0 5.7 16.2 4.7 9.2 5.3 5.7 10.0 15.2 9.5 7.5 10.8 15.0 24.0 7.9 8.9 11.7 6.2 13.2 11.2 4.2 8.4 13.2 4.7 3.8 3.4 4.4 3.0 19.8 4.9 5.1 5.4 7.2 2.4 21.5 13.8 12.6 4.1 14.0 12.5 12.7 8.5 5.7 13.4 11.5 8.6 9.7 6.4 2.3 6.7 15.6 4.6 14.0 3.7 9.1 5.6 4.6 10.5 10.7 26.6 5.9 5.1 13.6 17.5 8.9 13.2 5.9 11.7 8.2 23.8 16.4 28.0 13.0 12.3 9.9 41.2 8.5 22.2 11.1 26.5 5.1 5.2 8.9 5.0 10.5 44.9 41.5 18.1 5.7 14.3 7.8 0.2 0.3 0.4 0.3 0.3 0.5 0.4 0.4 0.5 0.3 0.2 0.2 0.4 0.5 0.3 0.4 2.2 1.0 0.2 4.8 5.3 5.5 4.2 4.3 4.0 7.4 6.6 6.0 7.5 7.9 8.4 11.3 9.6 8.4 19.9 13.9 15.9 7.4 4.8 8.6 11.3 26.5 10.4 3.6 14.3 5.0 16.5 41.7 10.1 40.8 60.0 7.9 4.9 5.2 32.7 7.6 6.6 31.3 6.1 54.4 10.3 11.4 5.1 14.3 43.7 3.8 4.7 8.2 41.6 10.7 1.7 32.3 14.0 0.0 23.3 16.2 10.1 2.8 23.1 12.4 119.9 13.1 5.1 4.1 41.7 39.7 7.4 19.5 2.2 11.5 8.5 22.6 32.3 5.8 5.8 6.6 7.7 9.8 18.3 7.0 7.9 18.9 11.5 17.6 7.6 23.4 14.3 ZSCAN12 "dJ29K1.2, KIAA0426, ZFP96, ZNF29K1, ZNF305, ZNF96" ENSG00000158691 "Zinc finger and SCAN domain containing 12" O43309 6 28378955-28399734 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006637, HPA007018" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA006637: AB_1080646, HPA007018: " "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (8.35e-4)" "unprognostic (1.51e-2)" "unprognostic (9.99e-2)" "unprognostic (1.00e-3)" "unprognostic (4.73e-2)" "unprognostic (9.96e-2)" "unprognostic (1.91e-2)" "unprognostic (2.35e-1)" "unprognostic (4.44e-2)" "unprognostic (1.71e-1)" "unprognostic (6.25e-3)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" 2.4 2.3 1.8 2.6 2.0 2.2 5.6 3.6 2.5 3.6 1.6 2.9 2.5 4.3 3.6 1.8 3.0 2.3 2.4 1.8 2.2 2.9 1.6 2.9 4.7 1.7 2.1 5.5 3.2 4.0 2.0 3.6 1.6 4.3 2.9 6.8 3.1 3.7 0.9 1.8 2.7 3.6 1.6 3.9 2.9 4.1 2.2 5.1 5.1 1.7 4.1 3.1 2.9 2.0 5.5 1.8 8.1 0.1 4.1 3.2 5.7 3.7 5.1 5.5 7.6 1.2 2.0 5.3 6.8 2.6 2.8 2.4 0.0 4.6 5.6 0.0 6.6 7.6 5.6 3.8 3.8 2.7 1.8 4.2 4.3 5.5 9.9 6.0 1.5 0.0 11.4 1.1 3.5 0.6 0.0 6.1 5.1 0.5 0.9 9.2 7.3 1.4 4.1 3.5 9.8 10.0 1.9 4.3 6.4 8.0 1.7 6.7 1.5 2.2 4.6 1.7 3.0 3.1 3.4 1.0 1.9 0.7 3.4 2.4 0.7 1.5 1.5 0.4 1.4 1.8 1.1 1.8 1.0 2.7 1.8 1.6 0.2 1.8 0.8 0.9 0.9 0.8 1.8 2.0 3.6 2.5 1.8 2.2 1.7 2.1 1.6 1.6 2.2 2.0 2.1 6.4 5.1 4.6 4.0 0.4 1.1 0.9 0.6 6.1 2.6 2.5 3.2 1.5 6.5 0.0 4.2 1.5 3.6 0.3 1.9 1.7 31.8 0.6 2.4 1.9 1.2 2.1 6.9 2.6 1.0 2.7 1.5 0.9 1.3 5.5 3.3 1.0 1.0 6.7 7.0 1.2 0.0 1.3 1.1 9.7 1.8 1.1 1.8 1.0 1.8 4.9 2.1 10.1 6.2 1.3 0.3 3.4 2.4 1.5 1.5 1.2 0.6 6.0 6.6 1.7 2.4 12.6 3.9 1.2 0.3 0.5 1.5 4.2 2.1 0.7 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4 ZSCAN29 "FLJ35867, Zfp690, ZNF690" ENSG00000140265 "Zinc finger and SCAN domain containing 29" Q8IWY8 15 43358172-43371025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007241, HPA011109" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Actin filaments" "HPA007241: AB_10600420, HPA011109: AB_10611525" "unprognostic (3.90e-2)" "unprognostic (2.70e-1)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-1)" "unprognostic (2.12e-2)" "unprognostic (4.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.44e-3)" "unprognostic (9.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (8.33e-2)" "unprognostic (3.43e-2)" 6.3 5.6 7.9 8.6 10.1 5.6 6.8 8.1 7.4 7.2 8.1 7.6 8.8 8.9 5.2 7.2 6.4 6.0 5.5 6.6 7.4 5.7 6.9 6.9 10.7 9.3 9.7 7.4 11.4 7.7 5.5 8.1 8.9 6.8 7.6 13.6 8.5 6.5 9.7 5.8 9.9 6.4 7.7 9.0 8.8 17.3 8.5 10.7 7.2 8.5 10.4 6.6 6.0 10.3 11.7 12.5 28.9 17.9 10.0 10.5 15.6 9.0 13.9 15.6 16.2 19.7 8.1 11.4 14.7 11.1 12.6 33.7 21.5 11.0 13.9 29.6 11.8 25.1 20.5 15.5 11.1 17.3 21.2 9.3 19.0 10.6 14.9 11.0 8.0 17.3 23.7 13.5 12.7 7.4 16.7 14.2 14.5 17.1 9.6 25.7 16.1 14.0 9.1 13.9 20.6 22.2 13.9 22.5 10.4 14.5 15.8 26.6 9.1 18.3 14.4 14.0 16.4 25.8 38.4 21.6 10.7 16.9 14.1 0.4 0.3 3.1 0.4 0.4 0.3 0.8 0.4 0.3 0.4 0.5 0.2 0.6 0.7 1.0 0.3 0.3 0.8 0.3 7.9 10.1 8.1 7.4 6.6 7.4 9.3 9.7 8.9 7.7 8.5 10.3 3.5 6.4 7.9 6.8 5.8 3.6 2.6 3.7 4.6 10.8 4.8 4.8 7.8 4.3 7.8 7.3 27.1 5.1 7.1 11.0 0.0 5.4 81.7 5.0 8.2 4.9 6.1 1.3 6.4 7.1 4.4 5.8 9.7 7.8 0.0 6.5 3.9 7.2 5.8 13.5 5.2 8.1 4.1 10.6 3.7 20.7 6.8 4.8 5.4 9.4 6.7 5.5 10.3 10.1 10.2 8.7 5.0 6.0 3.3 3.9 7.7 2.6 5.2 18.0 0.0 4.9 3.8 12.0 6.7 4.4 3.1 3.8 4.2 2.8 7.0 2.4 ZSWIM3 "C20orf164, dJ337O18.7, PPP1R174" ENSG00000132801 "Zinc finger SWIM-type containing 3" Q96MP5 20 45857614-45879122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.6;Inhibitory neurons: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055692, HPA060508" Uncertain Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Vesicles "Nucleoli fibrillar center, Cytosol" "HPA055692: AB_2682887, HPA060508: AB_2684297" "prognostic unfavorable (9.32e-5)" "unprognostic (8.53e-2)" "unprognostic (3.55e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (4.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.77e-3)" "unprognostic (4.49e-2)" "unprognostic (2.20e-1)" "unprognostic (1.36e-2)" "unprognostic (2.72e-3)" "unprognostic (9.28e-2)" "unprognostic (4.74e-2)" "unprognostic (5.55e-2)" "unprognostic (1.76e-1)" "unprognostic (4.69e-2)" "unprognostic (4.13e-2)" 1.3 2.9 2.3 2.0 2.2 0.7 1.8 2.8 2.5 1.8 1.4 2.3 2.4 1.9 2.8 1.8 2.1 1.5 2.0 2.1 2.3 1.8 2.3 1.9 3.4 2.0 2.1 2.7 1.5 2.2 1.9 1.7 2.1 1.9 2.3 3.3 1.8 1.6 1.4 2.2 2.4 1.7 2.0 3.2 1.8 3.2 2.2 3.5 1.9 2.4 3.9 1.6 1.4 2.1 1.7 1.4 4.1 2.4 4.9 3.5 2.4 2.6 3.1 4.7 4.6 5.9 2.6 5.3 8.8 2.2 2.3 2.8 5.9 2.8 3.5 3.3 2.5 5.1 2.6 3.8 5.9 2.9 6.7 3.2 3.1 3.6 2.2 5.0 4.1 4.6 4.8 2.5 3.6 8.5 4.0 5.8 1.6 3.9 5.6 3.9 3.8 4.0 1.3 1.0 5.4 2.7 4.2 4.8 3.3 3.1 2.3 7.6 4.1 4.7 1.5 1.8 1.6 5.4 3.0 3.4 4.0 3.4 1.5 1.0 1.1 1.6 1.3 1.5 2.8 2.1 1.5 2.0 1.9 1.8 1.4 1.9 0.8 1.7 4.8 1.1 2.4 1.1 2.3 2.2 2.8 2.5 2.1 2.3 2.0 2.1 2.1 2.0 2.2 2.1 1.6 3.2 1.1 4.6 4.1 0.4 0.3 0.7 0.6 4.4 1.1 1.0 1.3 0.0 0.5 1.8 0.0 1.3 1.4 2.8 0.0 1.2 0.5 0.6 1.2 1.8 2.4 0.8 7.6 1.4 0.6 1.4 1.5 1.0 0.0 5.2 2.2 0.8 1.0 0.0 9.2 1.1 0.0 1.3 1.4 0.7 0.3 1.1 0.0 6.5 0.6 2.8 0.0 7.1 7.0 0.6 0.3 1.2 2.6 0.2 2.0 1.2 0.5 4.3 0.0 1.3 1.2 2.4 4.3 1.3 0.3 0.8 3.1 4.7 0.9 0.4 ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 43.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 133.0;Extravillous trophoblasts: 108.6;Late spermatids: 208.8;Spermatocytes: 121.0;Spermatogonia: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (5.59e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (9.38e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.77e-8)" "unprognostic (6.36e-3)" "unprognostic (5.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-3)" "unprognostic (1.86e-2)" "prognostic unfavorable (3.72e-12)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (5.47e-2)" "unprognostic (3.46e-1)" 2.6 2.5 1.2 15.7 1.3 41.6 6.5 1.1 1.8 3.9 1.0 18.8 13.7 3.2 1.7 12.4 2.8 2.4 1.5 1.5 1.2 4.4 4.8 2.9 26.5 1.2 1.3 1.5 2.4 5.4 0.8 10.8 1.2 2.5 22.4 0.5 3.3 1.4 0.3 10.8 14.8 6.8 1.2 5.0 12.5 26.1 1.6 43.5 3.9 0.7 33.0 5.0 4.3 1.4 199.8 154.8 107.9 120.9 7.5 10.8 88.1 143.1 108.0 169.6 153.4 275.4 116.1 102.0 53.2 49.6 79.1 99.9 153.2 108.3 156.7 259.9 80.2 101.6 120.8 129.4 0.7 169.6 131.0 5.1 6.8 157.7 64.9 20.8 86.8 134.2 140.2 121.4 151.1 160.1 150.7 108.3 77.0 135.9 188.7 151.7 209.5 54.0 53.5 87.5 99.8 61.2 135.2 304.2 35.3 62.2 197.3 163.4 47.4 73.6 189.4 76.9 223.2 105.8 55.3 176.0 103.8 210.0 94.7 0.0 0.8 0.7 2.4 3.0 0.3 1.6 5.3 3.6 1.4 0.3 6.3 3.6 0.0 3.5 2.3 1.1 17.0 3.1 1.2 1.3 1.1 1.8 1.5 1.2 1.2 1.3 1.2 1.2 1.6 1.4 0.9 3.2 1.7 0.3 11.1 18.4 6.0 20.2 4.6 2.0 9.4 5.5 1.4 2.8 7.3 5.5 0.0 73.7 3.3 17.9 0.0 9.7 74.0 7.0 4.3 5.7 0.0 133.0 1.3 13.3 108.6 10.3 16.8 8.0 0.0 27.6 7.9 3.5 49.4 0.0 0.3 22.8 14.2 8.5 8.8 208.8 5.0 9.2 7.2 0.0 2.6 1.3 0.0 0.0 0.6 8.6 16.4 2.6 42.4 1.9 8.7 6.0 2.5 0.9 0.0 1.4 10.6 121.0 100.3 24.5 8.2 23.1 7.9 6.5 39.4 8.4 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4 ZZZ3 "ATAC1, DKFZP564I052" ENSG00000036549 "Zinc finger ZZ-type containing 3" Q8IYH5 1 77562416-77683419 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 73.8;Excitatory neurons: 102.1;Inhibitory neurons: 100.7;Microglial cells: 77.8;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 280.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053663, HPA054913, HPA066197" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA053663: AB_2682222, HPA054913: AB_2682640, HPA066197: AB_2685635" "unprognostic (1.30e-1)" "unprognostic (4.78e-2)" "unprognostic (2.73e-2)" "unprognostic (2.13e-3)" "unprognostic (5.38e-3)" "unprognostic (8.77e-2)" "prognostic unfavorable (6.96e-5)" "unprognostic (2.91e-1)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "unprognostic (2.83e-1)" "unprognostic (1.91e-1)" "unprognostic (1.71e-1)" "unprognostic (3.96e-1)" "unprognostic (1.95e-1)" "unprognostic (3.05e-2)" "unprognostic (1.43e-1)" 8.9 12.2 6.3 10.2 10.8 9.7 17.1 5.6 6.9 13.0 2.6 9.6 9.0 13.0 9.2 9.8 11.2 8.6 11.1 5.3 7.5 14.5 16.7 8.2 12.8 5.7 7.2 16.9 9.7 13.9 6.0 10.5 8.0 11.9 9.5 11.3 10.4 12.2 8.7 10.8 8.1 12.0 7.1 9.8 10.4 6.5 7.9 14.3 19.8 10.2 12.4 10.4 6.5 16.0 27.9 12.4 22.4 17.9 21.3 30.3 26.0 32.6 27.9 27.7 31.3 15.5 12.9 34.8 29.3 27.2 32.3 24.3 29.3 22.2 44.4 25.9 26.9 41.1 26.9 19.8 33.2 45.5 12.0 26.0 34.2 31.0 63.4 30.1 31.2 24.2 41.4 24.0 27.3 13.1 22.0 13.7 35.1 15.9 29.5 25.9 40.3 17.1 22.5 26.1 30.0 26.5 19.2 23.0 60.6 16.4 13.0 25.7 24.9 23.7 29.9 40.2 44.6 20.3 30.8 36.7 27.2 39.2 19.3 0.1 4.3 5.3 6.1 4.5 9.6 7.3 7.6 7.7 7.4 9.0 9.5 8.6 0.8 7.8 5.0 4.9 10.4 5.1 6.3 10.8 5.6 6.9 5.3 7.5 5.7 7.2 8.0 7.1 7.9 16.0 11.3 0.0 0.0 73.8 22.2 17.2 13.6 10.9 27.9 18.1 0.0 0.0 0.0 15.7 5.6 0.0 8.4 13.3 14.3 6.9 0.0 0.0 5.1 0.0 0.0 10.5 19.8 17.4 102.1 0.0 12.3 11.0 16.3 0.0 0.0 0.0 15.0 15.1 14.1 16.8 100.7 14.1 6.1 13.2 11.8 3.9 16.8 8.2 12.4 77.8 7.5 16.1 17.5 141.8 280.3 0.0 14.0 19.5 14.9 18.7 10.1 0.0 4.2 19.7 6.6 29.6 11.4 7.8 9.7 28.1 19.6 8.5 14.2 0.0 14.2 14.2