Immune cell - NBPF9 - The Human Protein Atlas

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NBPF9
Gene descriptionⁱ Full gene name according to HGNC.	NBPF member 9
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular

IMMUNE CELL SECTION SUMMARY
Immune cell type expression clusterⁱ The RNA data is used to cluster genes according to their expression across immune cells. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Basophils - Unknown function (mainly)
Immune cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Immune cell enhanced (basophil)
Immune cell type distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Immune cell lineage specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: lineage enriched, group enriched, lineage enhanced, low lineage specificity and not detected. Lineages include B-cells, T-cells, NK-cells, monocytes, granulocytes and dendritic cells. Read more	Group enriched (granulocytes, monocytes)
Immune cell lineage distributionⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Detected in all

IMMUNE CELL TYPE EXPRESSION (RNA)ⁱ

HPA datasetⁱ

Lineage

Expression

Alphabetical

Immune cell type specificity: Immune cell enhanced (basophil)

Monaco datasetⁱ

Lineage

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

NBPF9 is part of cluster 17 Basophils - Unknown function with confidenceⁱ 1
232 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on immune cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
DYDC1	DPY30 domain containing 1	0.8999	17
ABCA13	ATP binding cassette subfamily A member 13	0.8879	17
MAGEA10	MAGE family member A10	0.8483	17
MALL	Mal, T cell differentiation protein like	0.8465	17
MT-ND1	Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1	0.8443	41
NCCRP1	NCCRP1, F-box associated domain containing	0.8443	17
SLC15A1	Solute carrier family 15 member 1	0.8438	17
CDK12	Cyclin dependent kinase 12	0.8425	17
FKBPL	FKBP prolyl isomerase like	0.8380	17
RUSC2	RUN and SH3 domain containing 2	0.8345	41
INMT	Indolethylamine N-methyltransferase	0.8318	17
HAPLN4	Hyaluronan and proteoglycan link protein 4	0.8260	41
GJC1	Gap junction protein gamma 1	0.8260	17
SHISA9	Shisa family member 9	0.8251	17
PRELP	Proline and arginine rich end leucine rich repeat protein	0.8229	17