Cell line - TMEM161A - The Human Protein Atlas

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TMEM161A

SUMMARY

TISSUE

BRAIN

SINGLE CELL

TISSUE CELL

PATHOLOGY

IMMUNE

BLOOD

SUBCELL

CELL LINE

METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TMEM161A
Gene descriptionⁱ Full gene name according to HGNC.	Transmembrane protein 161A
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	RPMI-8226 - Immune response (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

TMEM161A is part of cluster 25 RPMI-8226 - Immune response with confidenceⁱ 0.81
313 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
FAM3A	FAM3 metabolism regulating signaling molecule A	0.6532	38
TMEM187	Transmembrane protein 187	0.5945	38
ABHD3	Abhydrolase domain containing 3, phospholipase	0.5840	25
IRAK1	Interleukin 1 receptor associated kinase 1	0.5603	40
SLC25A42	Solute carrier family 25 member 42	0.5583	1
SCAMP3	Secretory carrier membrane protein 3	0.5551	19
TSR3	TSR3 ribosome maturation factor	0.5538	19
GCDH	Glutaryl-CoA dehydrogenase	0.5512	25
NUDT8	Nudix hydrolase 8	0.5480	25
TTLL12	Tubulin tyrosine ligase like 12	0.5468	26
ADAP2	ArfGAP with dual PH domains 2	0.5460	25
TRPT1	TRNA phosphotransferase 1	0.5451	35
AIFM1	Apoptosis inducing factor mitochondria associated 1	0.5419	25
B3GAT3	Beta-1,3-glucuronyltransferase 3	0.5411	25
NAA10	N-alpha-acetyltransferase 10, NatA catalytic subunit	0.5401	19

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.