Cell line - MAPRE3 - The Human Protein Atlas

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MAPRE3

SUMMARY

TISSUE

BRAIN

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MAPRE3
Gene descriptionⁱ Full gene name according to HGNC.	Microtubule associated protein RP/EB family member 3
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	OE19 - Mitochondria (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Cell line enhanced (OE19)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

MAPRE3 is part of cluster 21 OE19 - Mitochondria with confidenceⁱ 1
502 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
FAIM2	Fas apoptotic inhibitory molecule 2	0.6547	11
MAGEA12	MAGE family member A12	0.6407	21
TMEM63B	Transmembrane protein 63B	0.6320	21
CSAG1	Chondrosarcoma associated gene 1	0.6196	21
NEIL2	Nei like DNA glycosylase 2	0.6160	17
SYT5	Synaptotagmin 5	0.6093	21
TEF	TEF transcription factor, PAR bZIP family member	0.6030	21
MAGEA6	MAGE family member A6	0.5970	21
PPM1N	Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)	0.5935	21
PRDM16	PR/SET domain 16	0.5909	21
FAM47E-STBD1	FAM47E-STBD1 readthrough	0.5874	21
LRRC66	Leucine rich repeat containing 66	0.5864	21
LRFN3	Leucine rich repeat and fibronectin type III domain containing 3	0.5850	19
IFT27	Intraflagellar transport 27	0.5723	17
TNNI3	Troponin I3, cardiac type	0.5721	21

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.