Cell line - TANGO6 - The Human Protein Atlas

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TANGO6

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GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TANGO6
Gene descriptionⁱ Full gene name according to HGNC.	Transport and golgi organization 6 homolog
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Cell cycle regulation (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

TANGO6 is part of cluster 26 Non-specific - Cell cycle regulation with confidenceⁱ 0.9
1622 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
ADAT1	Adenosine deaminase tRNA specific 1	0.6425	26
VPS4A	Vacuolar protein sorting 4 homolog A	0.6322	26
OGFOD1	2-oxoglutarate and iron dependent oxygenase domain containing 1	0.6168	26
COG4	Component of oligomeric golgi complex 4	0.5998	26
UTP4	UTP4 small subunit processome component	0.5962	26
DDX19A	DEAD-box helicase 19A	0.5887	26
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2	0.5870	10
RSPRY1	Ring finger and SPRY domain containing 1	0.5787	26
ABCF2-H2BE1	ABCF2-H2BE1 readthrough	0.5743	26
TERF2	Telomeric repeat binding factor 2	0.5725	26
AC026464.4	Novel protein	0.5721	26
CENPT	Centromere protein T	0.5692	10
MSL3	MSL complex subunit 3	0.5642	41
KARS1	Lysyl-tRNA synthetase 1	0.5636	26
NRG1	Neuregulin 1	0.5630	10

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.