Cell line - RSRC2 - The Human Protein Atlas

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RSRC2

SUMMARY

TISSUE

BRAIN

SINGLE CELL

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PATHOLOGY

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RSRC2
Gene descriptionⁱ Full gene name according to HGNC.	Arginine and serine rich coiled-coil 2
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Cell cycle regulation (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

RSRC2 is part of cluster 26 Non-specific - Cell cycle regulation with confidenceⁱ 1
1622 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
UBE2K	Ubiquitin conjugating enzyme E2 K	0.7198	26
RNF34	Ring finger protein 34	0.6771	44
SUPT5H	SPT5 homolog, DSIF elongation factor subunit	0.6522	26
HNRNPM	Heterogeneous nuclear ribonucleoprotein M	0.6387	26
RAB35	RAB35, member RAS oncogene family	0.6269	26
MFAP1	Microfibril associated protein 1	0.6138	26
LARP4	La ribonucleoprotein 4	0.6105	26
PSMD9	Proteasome 26S subunit, non-ATPase 9	0.5951	40
SETD2	SET domain containing 2, histone lysine methyltransferase	0.5864	26
AC003006.1	Novel protein	0.5796	16
PRPF39	Pre-mRNA processing factor 39	0.5666	26
CCDC12	Coiled-coil domain containing 12	0.5648	16
AC006486.1	Novel protein	0.5636	15
GTF3C6	General transcription factor IIIC subunit 6	0.5609	26
RAP1B	RAP1B, member of RAS oncogene family	0.5601	36

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.