Cell line - STAM2 - The Human Protein Atlas

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STAM2

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GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	STAM2
Gene descriptionⁱ Full gene name according to HGNC.	Signal transducing adaptor molecule 2
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Epithelial cell lines - Translation (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

STAM2 is part of cluster 30 Epithelial cell lines - Translation with confidenceⁱ 1
739 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
CA5B	Carbonic anhydrase 5B	0.7206	30
TMEM167B	Transmembrane protein 167B	0.6664	30
RAD23A	RAD23 homolog A, nucleotide excision repair protein	0.6348	30
GTF2H1	General transcription factor IIH subunit 1	0.6324	30
SPRYD7	SPRY domain containing 7	0.6314	30
FOLR3	Folate receptor gamma	0.6223	30
DUSP7	Dual specificity phosphatase 7	0.6186	30
CSGALNACT2	Chondroitin sulfate N-acetylgalactosaminyltransferase 2	0.6095	30
KCNMA1	Potassium calcium-activated channel subfamily M alpha 1	0.6091	10
CLMP	CXADR like membrane protein	0.6051	10
ZFAND2B	Zinc finger AN1-type containing 2B	0.5974	30
NSMAF	Neutral sphingomyelinase activation associated factor	0.5929	30
MAP3K20	Mitogen-activated protein kinase kinase kinase 20	0.5905	10
SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	0.5757	30
SH3BGRL3	SH3 domain binding glutamate rich protein like 3	0.5725	11

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.