Cell line - ZNF428 - The Human Protein Atlas

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ZNF428

SUMMARY

TISSUE

BRAIN

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PATHOLOGY

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ZNF428
Gene descriptionⁱ Full gene name according to HGNC.	Zinc finger protein 428
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	REH - Unknown function (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

ZNF428 is part of cluster 14 REH - Unknown function with confidenceⁱ 1
148 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
CMTM1	CKLF like MARVEL transmembrane domain containing 1	0.6437	14
DUSP15	Dual specificity phosphatase 15	0.6366	14
ZNF764	Zinc finger protein 764	0.6221	14
CKLF-CMTM1	CKLF-CMTM1 readthrough	0.6083	14
C1QTNF4	C1q and TNF related 4	0.5937	14
LIG1	DNA ligase 1	0.5933	24
LCN6	Lipocalin 6	0.5909	14
MSI2	Musashi RNA binding protein 2	0.5879	14
ZC3H4	Zinc finger CCCH-type containing 4	0.5866	14
AC233755.1	Immunoglobulin heavy variable 4-38-2-like	0.5860	14
SMN1	Survival of motor neuron 1, telomeric	0.5830	17
C11orf95	Chromosome 11 open reading frame 95	0.5818	12
KLHL33	Kelch like family member 33	0.5800	14
SHANK1	SH3 and multiple ankyrin repeat domains 1	0.5767	9
DBN1	Drebrin 1	0.5755	12

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.