CELF1 protein expression summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

Search result

Field

Cluster

Cluster

Pathway

HELP

NEWS

CELF1

SUMMARY

TISSUE

BRAIN

SINGLE CELL

TISSUE CELL

PATHOLOGY

IMMUNE

BLOOD

SUBCELL

CELL LINE

METABOLIC

HUMAN PROTEIN ATLAS SUMMARYⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Proteinⁱ Full gene name according to HGNC.	CUGBP Elav-like family member 1
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CELF1 (BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR)
Tissue specificityⁱ ??The RNA specificity category is based on mRNA expression levels in the consensus dataset which is calculated from the RNA expression levels in samples from HPA and GTEX. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Tissue expression clusterⁱ The RNA data was used to cluster genes according to their expression across tissues. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Mitochondria & Proteasome (mainly)
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Single cell type expression clusterⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Transcription (mainly)
Immune cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed blood cell samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low immune cell specificity
Brain specificityⁱ The regional specificity category is based on mRNA expression levels in the analysed brain samples, grouped into 13 main brain regions and calculated for the three different species. All brain expression profiles are based on data from HPA. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category Read more	Low human brain regional specificity
Cancer prognostic summary	Prognostic marker in liver cancer (unfavorable)
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Subcellular summaryⁱ Describes the main and potential additional location(s) of the encoded protein according to ICC-IF resukt in the Cell Atlas, as well as potential data regarding cell cycle depency (CCD) for the RNA and/or protein expression.	Located in Nucleoplasm
Protein function (UniProt)ⁱ Useful information about the protein provided by UniProt.	RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB. Promotes exclusion of exon 11 of the INSR pre-mRNA. Inhibits, together with HNRNPH1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Increases translation and controls the choice of translation initiation codon of CEBPB mRNA. Increases mRNA translation of CEBPB in aging liver (By similarity). Increases translation of CDKN1A mRNA by antagonizing the repressive effect of CALR3. Mediates rapid cytoplasmic mRNA deadenylation. Recruits the deadenylase PARN to the poly(A) tail of EDEN-containing mRNAs to promote their deadenylation. Required for completion of spermatogenesis (By similarity). Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK and to Bruno response elements (BREs). Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. Binds to AU-rich sequences (AREs or EDEN-like) localized in the 3'-UTR of JUN and FOS mRNAs. Binds to the IR RNA. Binds to the 5'-region of CDKN1A and CEBPB mRNAs. Binds with the 5'-region of CEBPB mRNA in aging liver. May be a specific regulator of miRNA biogenesis. Binds to primary microRNA pri-MIR140 and, with CELF2, negatively regulates the processing to mature miRNA 1.... show less
Molecular function (UniProt)ⁱ Keywords assigned by UniProt to proteins due to their particular molecular function.	Activator, RNA-binding
Biological process (UniProt)ⁱ Keywords assigned by UniProt to proteins because they are involved in a particular biological process.	mRNA processing, mRNA splicing
Gene summary (Entrez)ⁱ Useful information about the gene from Entrez	Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]... show less

TISSUEⁱ Summary of data presented in the Tissue section, with a representative image of protein expression (left) and an interactive chart showing the tissue-specific mRNA expression (right). The image and the chart are clickable and will redirect to more Tissue data. This section contains information regarding the expression profiles of protein-coding genes in normal human tissue, both on the mRNA and protein level. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more

Tissue expression clusterⁱ The RNA data was used to cluster genes according to their expression across tissues. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Mitochondria & Proteasome (mainly)
Tissue specificityⁱ The RNA specificity category is based on mRNA expression levels in the consensus dataset which is calculated from the RNA expression levels in samples from HPA and GTEX. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Tissue distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA and GTEX. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Protein expressionⁱ A summary of the overall protein expression pattern across the analyzed normal tissues. The summary is based on knowledge-based annotation. "Estimation of protein expression could not be performed. View primary data." is shown for genes analyzed with a knowledge-based approach where available RNA-seq and gene/protein characterization data has been evaluated as not sufficient in combination with immunohistochemistry data to yield a reliable estimation of the protein expression profile. Read more	Mainly nuclear expression in all tissues.

BRAINⁱ Summary of data presented in the Brain Atlas and a representative image of mRNA expression in the human brain. The image is clickable and will redirect to more Brain Atlas data. The Brain Atlas explores the protein expression in the mammalian brain by visualization and integration of data from three mammalian species (human, pig and mouse). Transcriptomics data combined with affinity-based protein in situ localization down to single cell level is available in a brain-centric sub atlas of the Human Protein Atlas. Read more

Human regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analysed brain samples, grouped into 13 main brain regions and calculated for the three different species. All brain expression profiles are based on data from HPA. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity
Pig regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analysed brain samples, grouped into 13 main brain regions and calculated for the three different species. All brain expression profiles are based on data from HPA. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity
Mouse regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analysed brain samples, grouped into 13 main brain regions and calculated for the three different species. All brain expression profiles are based on data from HPA. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity

SINGLE CELL TYPEⁱ Summary of data presented in the Single cell Type section, with an interactive chart showing the cell type-specific mRNA expression. The chart is clickable and will redirect to more Cell Type data. This section contains information about single cell type RNA expression based on scRNAseq of human tissues. The data also covers transcriptomics analysis of human blood and cultured cell lines. Read more

Single cell type expression clusterⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Transcription (mainly)
Cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity

TISSUE CELL TYPEⁱ

Classificationⁱ

No predicted cell type specificity

PATHOLOGYⁱ Summary of data presented in the Pathology section, with representative images of protein expression in cancer (left) and correlation between mRNA expression and patient survival (right). Images are clickable and redirect to pages with more Pathology data. This section contains mRNA and protein expression data from 17 different forms of human cancer, as well as correlation analysis of mRNA expression and patient survival. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more
	Liver cancer p<0.001
Prognostic summary	Prognostic marker in liver cancer (unfavorable)
Cancer specificityⁱ Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected. Read more	Low cancer specificity
Cancer distributionⁱ Distribution of RNA expression in 17 cancer types is categorized as either detected in single, detected in some, detected in many, detected in all, or not detected. Read more	Detected in all

IMMUNE CELLⁱ Summary of data presented in the Immune Cell section and a representative image of mRNA expression in immune cells in the blood. The image is clickable and will redirect to more immune cell related data. The Immune Cell section contains information regarding single cell type mRNA expression profiles of protein-coding genes in various immune cells in the blood, e.g. B-cells and granulocytes. Read more

Immune cell expression clusterⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Eosinophils - Innate immune response (mainly)
Immune cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low immune cell specificity

BLOOD PROTEINⁱ Summary of data presented in the Blood proteins section and a representative image of the concentration in plasma and related function for the protein in plasma. The image is clickable and will redirect to more data. The Blood proteins section contains plasma levels of proteins detected in human blood and an analysis of the human secretome (including annotation of the genes predicted to be actively secreted to human blood) is also presented. Read more
Detected in blood by immunoassayⁱ The blood-based immunoassay category applies to actively secreted proteins and is based on plasma or serum protein concentrations established with enzyme-linked immunosorbent assays, compiled from a literature search. The categories include: detected and not detected, where detection refers to a concentration found in the literature search. Read more	No (not applicable)
Detected in blood by mass spectrometryⁱ Detection or not of the gene in blood, based on spectral count estimations from a publicly available mass spectrometry-based plasma proteomics data set obtained from the PeptideAtlas.	No
Detected in blood by proximity extension assayⁱ Detection or not of the gene in blood, based on proximity extension assays (Olink) for a longitudinal wellness study covering 76 individuals with three visits during two years. Read more	No

SUBCELLULARⁱ Summary of data presented in the Cell Atlas and a representative image of subcellular localization. The Cell Atlas provides RNA expression data derived from RNA sequencing of a large panel of cell lines and protein localization data derived from antibody-based profiling by immunofluorescence confocal microscopy, using a subset of cell lines selected based on RNA expression. Read more

Main locationⁱ Main subcellular location(s) and reliability score(s) for the encoded protein(s) in human cells. The main location(s) may be characterized by presence in all tested cell lines and/or ihigher staining intensity compared to the potential additional location(s). If available, links to overrepresentation analyses in Reactome, a free, open-source, curated and peer reviewed biological pathway database, are provided. An analysis is done for the corresponding gene set of the proteome localizing to the main and additional locations of the protein on this page, respectively. Read more	Localized to the Nucleoplasm

CELL LINEⁱ Summary of data presented in the Cell Line section and a representative image of mRNA expression across different human cell lines. The image is clickable and will redirect to more cell line data. This section contains information regarding mRNA expression profiles of human protein-coding genes for a large variety of cell lines. Read more

Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	HeLa - Mitochondria (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell type distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all

METABOLIC

Metabolic info	Not available

GENE INFORMATIONⁱ Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	CELF1 (HGNC Symbol)
Synonyms	BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR
Description	CUGBP Elav-like family member 1 (HGNC Symbol)
Chromosome	11
Cytoband	p11.2
Chromosome location (bp)	47465933 - 47565569
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	15
Protein evidence	Evidence at protein level (all genes)
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Ensembl	ENSG00000149187 (version 103.38)
Entrez gene	10658
UniProt	Q92879 (UniProt - Evidence at protein level)
neXtProt	NX_Q92879
Antibodypedia	CELF1 antibodies

PROTEIN BROWSERⁱ

«

CELF1-201

CELF1-202

CELF1-203

CELF1-204

CELF1-205

CELF1-208

CELF1-209

CELF1-210

CELF1-211

CELF1-212

CELF1-213

CELF1-214

CELF1-215

CELF1-218

CELF1-221

»

PROTEIN INFORMATIONⁱ The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database. The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein. The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class. The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CELF1-201 ENSP00000308386 ENST00000310513	Q92879 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000900 [translation repressor activity, mRNA regulatory element binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0006397 [mRNA processing] GO:0007281 [germ cell development] GO:0008285 [negative regulation of cell population proliferation] GO:0008380 [RNA splicing] GO:0009792 [embryo development ending in birth or egg hatching] GO:0010494 [cytoplasmic stress granule] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016246 [RNA interference] GO:0016441 [posttranscriptional gene silencing] GO:0036002 [pre-mRNA binding] GO:0042835 [BRE binding] GO:0043484 [regulation of RNA splicing] GO:0050727 [regulation of inflammatory response] GO:0061157 [mRNA destabilization] GO:0097356 [perinucleolar compartment] GO:1990904 [ribonucleoprotein complex] Show all	482 aa 51.5 kDa	No	0
CELF1-202 ENSP00000351409 ENST00000358597	Q92879 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000900 [translation repressor activity, mRNA regulatory element binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0006397 [mRNA processing] GO:0007281 [germ cell development] GO:0008285 [negative regulation of cell population proliferation] GO:0008380 [RNA splicing] GO:0009792 [embryo development ending in birth or egg hatching] GO:0010494 [cytoplasmic stress granule] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016246 [RNA interference] GO:0016441 [posttranscriptional gene silencing] GO:0036002 [pre-mRNA binding] GO:0042835 [BRE binding] GO:0043484 [regulation of RNA splicing] GO:0050727 [regulation of inflammatory response] GO:0061157 [mRNA destabilization] GO:0097356 [perinucleolar compartment] GO:1990904 [ribonucleoprotein complex] Show all	486 aa 52.1 kDa	No	0
CELF1-203 ENSP00000354639 ENST00000361904	Q92879 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000900 [translation repressor activity, mRNA regulatory element binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0006397 [mRNA processing] GO:0007281 [germ cell development] GO:0008285 [negative regulation of cell population proliferation] GO:0008380 [RNA splicing] GO:0009792 [embryo development ending in birth or egg hatching] GO:0010494 [cytoplasmic stress granule] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016246 [RNA interference] GO:0016441 [posttranscriptional gene silencing] GO:0036002 [pre-mRNA binding] GO:0042835 [BRE binding] GO:0043484 [regulation of RNA splicing] GO:0050727 [regulation of inflammatory response] GO:0061157 [mRNA destabilization] GO:0097356 [perinucleolar compartment] GO:1990904 [ribonucleoprotein complex] Show all	483 aa 51.6 kDa	No	0
CELF1-204 ENSP00000378705 ENST00000395290	Q92879 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000900 [translation repressor activity, mRNA regulatory element binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0006397 [mRNA processing] GO:0007281 [germ cell development] GO:0008285 [negative regulation of cell population proliferation] GO:0008380 [RNA splicing] GO:0009792 [embryo development ending in birth or egg hatching] GO:0010494 [cytoplasmic stress granule] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016246 [RNA interference] GO:0016441 [posttranscriptional gene silencing] GO:0036002 [pre-mRNA binding] GO:0042835 [BRE binding] GO:0043484 [regulation of RNA splicing] GO:0050727 [regulation of inflammatory response] GO:0061157 [mRNA destabilization] GO:0097356 [perinucleolar compartment] GO:1990904 [ribonucleoprotein complex] Show all	485 aa 52 kDa	No	0
CELF1-205 ENSP00000378706 ENST00000395292	Q92879 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000900 [translation repressor activity, mRNA regulatory element binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0006397 [mRNA processing] GO:0007281 [germ cell development] GO:0008285 [negative regulation of cell population proliferation] GO:0008380 [RNA splicing] GO:0009792 [embryo development ending in birth or egg hatching] GO:0010494 [cytoplasmic stress granule] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016246 [RNA interference] GO:0016441 [posttranscriptional gene silencing] GO:0036002 [pre-mRNA binding] GO:0042835 [BRE binding] GO:0043484 [regulation of RNA splicing] GO:0050727 [regulation of inflammatory response] GO:0061157 [mRNA destabilization] GO:0097356 [perinucleolar compartment] GO:1990904 [ribonucleoprotein complex] Show all	483 aa 51.6 kDa	No	0
CELF1-208 ENSP00000436191 ENST00000525841	E9PQK4 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	87 aa 9.9 kDa	No	0
CELF1-209 ENSP00000438862 ENST00000526277	F5H3J7 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all		37 aa 4.1 kDa	No	0
CELF1-210 ENSP00000435423 ENST00000526419	E9PKA1 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	56 aa 6.5 kDa	No	0
CELF1-211 ENSP00000435320 ENST00000528434	E9PKU1 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	114 aa 12.9 kDa	No	0
CELF1-212 ENSP00000442415 ENST00000528538	F5H7M7 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all		14 aa 1.6 kDa	No	0
CELF1-213 ENSP00000433986 ENST00000530151	E9PSH0 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005737 [cytoplasm] GO:1990904 [ribonucleoprotein complex] Show all	95 aa 10.9 kDa	No	0
CELF1-214 ENSP00000436864 ENST00000531165	G5EA30 [Direct mapping] CUG triplet repeat, RNA binding protein 1, isoform CRA_c; CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0007286 [spermatid development] GO:0008285 [negative regulation of cell population proliferation] GO:0010628 [positive regulation of gene expression] GO:0016441 [posttranscriptional gene silencing] GO:0021987 [cerebral cortex development] GO:0031369 [translation initiation factor binding] GO:0040018 [positive regulation of multicellular organism growth] GO:0061157 [mRNA destabilization] GO:0071158 [positive regulation of cell cycle arrest] Show all	514 aa 55.1 kDa	No	0
CELF1-215 ENSP00000435926 ENST00000532048	Q92879 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000900 [translation repressor activity, mRNA regulatory element binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006376 [mRNA splice site selection] GO:0006397 [mRNA processing] GO:0007281 [germ cell development] GO:0008285 [negative regulation of cell population proliferation] GO:0008380 [RNA splicing] GO:0009792 [embryo development ending in birth or egg hatching] GO:0010494 [cytoplasmic stress granule] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016246 [RNA interference] GO:0016441 [posttranscriptional gene silencing] GO:0036002 [pre-mRNA binding] GO:0042835 [BRE binding] GO:0043484 [regulation of RNA splicing] GO:0050727 [regulation of inflammatory response] GO:0061157 [mRNA destabilization] GO:0097356 [perinucleolar compartment] GO:1990904 [ribonucleoprotein complex] Show all	512 aa 55 kDa	No	0
CELF1-218 ENSP00000438044 ENST00000535982	F5H0D8 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	103 aa 11.8 kDa	No	0
CELF1-221 ENSP00000444825 ENST00000543178	F5H4Y5 [Direct mapping] CUGBP Elav-like family member 1 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	78 aa 8.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.