Cell line - TTC39C - The Human Protein Atlas

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TTC39C

SUMMARY

TISSUE

BRAIN

SINGLE CELL

TISSUE CELL

PATHOLOGY

IMMUNE

BLOOD

SUBCELL

CELL LINE

METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TTC39C
Gene descriptionⁱ Full gene name according to HGNC.	Tetratricopeptide repeat domain 39C
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	HeLa - Mitochondria (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

TTC39C is part of cluster 20 HeLa - Mitochondria with confidenceⁱ 1
435 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
STAT6	Signal transducer and activator of transcription 6	0.6261	34
MT-ND4L	Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L	0.5957	20
KANK2	KN motif and ankyrin repeat domains 2	0.5903	34
MT-CYB	Mitochondrially encoded cytochrome b	0.5806	20
NPR3	Natriuretic peptide receptor 3	0.5698	20
GLT8D2	Glycosyltransferase 8 domain containing 2	0.5692	34
C1RL	Complement C1r subcomponent like	0.5650	34
IL11RA	Interleukin 11 receptor subunit alpha	0.5593	34
AP3S1	Adaptor related protein complex 3 subunit sigma 1	0.5565	34
MTRNR2L12	MT-RNR2 like 12	0.5462	20
MT-ND5	Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5	0.5453	20
VKORC1	Vitamin K epoxide reductase complex subunit 1	0.5354	34
CPM	Carboxypeptidase M	0.5354	34
MT-ND1	Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1	0.5320	20
MT-CO1	Mitochondrially encoded cytochrome c oxidase I	0.5296	20

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.