Cell line - ZNF318 - The Human Protein Atlas

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ZNF318

SUMMARY

TISSUE

BRAIN

SINGLE CELL

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PATHOLOGY

IMMUNE

BLOOD

SUBCELL

CELL LINE

METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ZNF318
Gene descriptionⁱ Full gene name according to HGNC.	Zinc finger protein 318
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	OE19 - Mitochondria (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

ZNF318 is part of cluster 21 OE19 - Mitochondria with confidenceⁱ 1
502 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
RPL7L1	Ribosomal protein L7 like 1	0.8087	21
CDC5L	Cell division cycle 5 like	0.7585	21
BICRAL	BRD4 interacting chromatin remodeling complex associated protein like	0.6751	21
INTS8	Integrator complex subunit 8	0.6694	21
SEH1L	SEH1 like nucleoporin	0.6587	21
HSP90AB1	Heat shock protein 90 alpha family class B member 1	0.6494	21
NFYA	Nuclear transcription factor Y subunit alpha	0.6492	21
XPO5	Exportin 5	0.6455	21
MRPS10	Mitochondrial ribosomal protein S10	0.6447	21
MED20	Mediator complex subunit 20	0.6330	21
DGCR6	DiGeorge syndrome critical region gene 6	0.6322	21
BNIP5	BCL2 interacting protein 5	0.6304	21
RALBP1	RalA binding protein 1	0.6170	21
RALYL	RALY RNA binding protein like	0.6142	21
RPL36A-HNRNPH2	RPL36A-HNRNPH2 readthrough	0.6055	32

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.