Cell line - RNPC3 - The Human Protein Atlas

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RNPC3

SUMMARY

TISSUE

BRAIN

SINGLE CELL

TISSUE CELL

PATHOLOGY

IMMUNE

BLOOD

SUBCELL

CELL LINE

METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RNPC3
Gene descriptionⁱ Full gene name according to HGNC.	RNA binding region (RNP1, RRM) containing 3
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	HeLa - Mitochondria (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

RNPC3 is part of cluster 20 HeLa - Mitochondria with confidenceⁱ 1
435 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
MT-ATP8	Mitochondrially encoded ATP synthase membrane subunit 8	0.7860	20
LUC7L3	LUC7 like 3 pre-mRNA splicing factor	0.7164	20
ARHGAP11B	Rho GTPase activating protein 11B	0.6848	20
MT-ATP6	Mitochondrially encoded ATP synthase membrane subunit 6	0.6806	20
TBXT	T-box transcription factor T	0.6662	20
MTRNR2L12	MT-RNR2 like 12	0.6623	20
MT-ND2	Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2	0.6601	20
SPDYE16	Speedy/RINGO cell cycle regulator family member E16	0.6538	20
IFNE	Interferon epsilon	0.6518	20
SAMD11	Sterile alpha motif domain containing 11	0.6504	20
MTRNR2L11	MT-RNR2 like 11	0.6457	20
FBXO46	F-box protein 46	0.6453	20
COL4A4	Collagen type IV alpha 4 chain	0.6433	20
PRSS36	Serine protease 36	0.6415	20
MTRNR2L8	MT-RNR2 like 8	0.6415	20

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.