Cell line - CDC42SE1 - The Human Protein Atlas

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CDC42SE1
Gene descriptionⁱ Full gene name according to HGNC.	CDC42 small effector 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	U-698-M & Daudi - Adaptive immune response (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Cell line enhanced (U-698)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

CDC42SE1 is part of cluster 27 U-698-M & Daudi - Adaptive immune response with confidenceⁱ 1
505 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
SETDB1	SET domain bifurcated histone lysine methyltransferase 1	0.8709	27
GOLPH3L	Golgi phosphoprotein 3 like	0.8686	27
MCL1	MCL1 apoptosis regulator, BCL2 family member	0.8660	27
ARNT	Aryl hydrocarbon receptor nuclear translocator	0.8557	27
CAMP	Cathelicidin antimicrobial peptide	0.8464	27
ENSA	Endosulfine alpha	0.8352	27
TBC1D22B	TBC1 domain family member 22B	0.8192	27
PLCG2	Phospholipase C gamma 2	0.8168	27
IGHG1	Immunoglobulin heavy constant gamma 1 (G1m marker)	0.8164	27
IGKJ5	Immunoglobulin kappa joining 5	0.8140	27
PYHIN1	Pyrin and HIN domain family member 1	0.8138	27
PRUNE1	Prune exopolyphosphatase 1	0.8111	27
TCL1B	TCL1 family AKT coactivator B	0.8107	27
SPATA48	Spermatogenesis associated 48	0.8099	27
NAPSA	Napsin A aspartic peptidase	0.8089	27