Cell line - TRBV2 - The Human Protein Atlas

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TRBV2

SUMMARY

TISSUE

BRAIN

SINGLE CELL

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PATHOLOGY

IMMUNE

BLOOD

SUBCELL

CELL LINE

METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TRBV2
Gene descriptionⁱ Full gene name according to HGNC.	T cell receptor beta variable 2
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	T-cell receptor genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	RPMI-8226 - Immune response (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Cell line enriched (RPMI-8226)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in single
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

TRBV2 is part of cluster 25 RPMI-8226 - Immune response with confidenceⁱ 1
313 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
CD8B	CD8b molecule	0.9897	25
CARNS1	Carnosine synthase 1	0.9893	25
IGKV1D-43	Immunoglobulin kappa variable 1D-43	0.9881	25
LILRA5	Leukocyte immunoglobulin like receptor A5	0.9879	25
IGLC3	Immunoglobulin lambda constant 3 (Kern-Oz+ marker)	0.9874	25
PVALB	Parvalbumin	0.9870	25
PLA2G4D	Phospholipase A2 group IVD	0.9844	25
CXCR3	C-X-C motif chemokine receptor 3	0.9844	25
PLA2G2D	Phospholipase A2 group IID	0.9842	25
CX3CR1	C-X3-C motif chemokine receptor 1	0.9840	25
CD177	CD177 molecule	0.9824	25
IGKV1D-42	Immunoglobulin kappa variable 1D-42 (non-functional)	0.9818	25
IGKV1D-8	Immunoglobulin kappa variable 1D-8	0.9816	25
LRRC26	Leucine rich repeat containing 26	0.9814	25
BSND	Barttin CLCNK type accessory subunit beta	0.9808	25

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.