Cell line - MTFP1 - The Human Protein Atlas

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MTFP1

SUMMARY

TISSUE

BRAIN

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MTFP1
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial fission process 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Non-specific - Cell cycle regulation (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

MTFP1 is part of cluster 26 Non-specific - Cell cycle regulation with confidenceⁱ 0.84
1622 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
DCTPP1	DCTP pyrophosphatase 1	0.7235	40
GOT2	Glutamic-oxaloacetic transaminase 2	0.7160	26
IDH3G	Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma	0.6374	40
WRAP53	WD repeat containing antisense to TP53	0.6253	26
NAA10	N-alpha-acetyltransferase 10, NatA catalytic subunit	0.6140	19
FMC1	Formation of mitochondrial complex V assembly factor 1 homolog	0.6134	19
ERH	ERH mRNA splicing and mitosis factor	0.6117	40
GEMIN4	Gem nuclear organelle associated protein 4	0.6099	26
AAAS	Aladin WD repeat nucleoporin	0.6006	26
EIF5A	Eukaryotic translation initiation factor 5A	0.6002	26
MRPL23	Mitochondrial ribosomal protein L23	0.5968	19
AHSA1	Activator of HSP90 ATPase activity 1	0.5885	40
BOLA2B	BolA family member 2B	0.5812	40
CENPM	Centromere protein M	0.5567	40
HAUS7	HAUS augmin like complex subunit 7	0.5547	40

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.