Cell line - HSPB9 - The Human Protein Atlas

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HSPB9

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GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	HSPB9
Gene descriptionⁱ Full gene name according to HGNC.	Heat shock protein family B (small) member 9
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	BEWO - Transcription regulation (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Cell line enhanced (BEWO, HEK93)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in some
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

HSPB9 is part of cluster 28 BEWO - Transcription regulation with confidenceⁱ 1
389 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
PRDM6	PR/SET domain 6	0.7455	28
ANKRD6	Ankyrin repeat domain 6	0.7423	28
REEP1	Receptor accessory protein 1	0.7379	28
DDX4	DEAD-box helicase 4	0.7368	28
YJEFN3	YjeF N-terminal domain containing 3	0.7326	19
MSMB	Microseminoprotein beta	0.7310	24
GPD1L	Glycerol-3-phosphate dehydrogenase 1 like	0.7261	28
NKD2	NKD inhibitor of WNT signaling pathway 2	0.7239	24
ATP6V1C2	ATPase H+ transporting V1 subunit C2	0.7089	28
GRIN2C	Glutamate ionotropic receptor NMDA type subunit 2C	0.6988	28
DLX5	Distal-less homeobox 5	0.6962	28
OR5H1	Olfactory receptor family 5 subfamily H member 1	0.6931	28
CMTM8	CKLF like MARVEL transmembrane domain containing 8	0.6915	28
GRHL1	Grainyhead like transcription factor 1	0.6905	28
ISYNA1	Inositol-3-phosphate synthase 1	0.6870	28

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.