The image of the month is a fluorescent antibody-based display of the glomerulus; the main filtrating unit within the kidney generated in the HPA group in Uppsala. The image is a result of a multiplex immunohistochemistry staining, where the podocyte protein podocin (gene: NPHS2) and five other proteins specific to different main structures within the kidney were stained and visualized through fluorescently tagged antibodies...Read more

The exploration of the human proteome has revealed many uncharacterized proteins with very interesting distributions in tissues and cells. Among them are many receptor proteins with unknown functions and predominant expression in the brain, including the orphan receptor GPR151...Read more

In this movie Professor Tomas Hökfelt (Karolinska Institutet) takes you on a journey to the areas of the brain affected by Alzheimer's disease...Read more

Cilia and flagella are fascinating organelles that can be seen as thin membrane-bound projections extending from the body of various cell types. Most well-known are the flagella of sperm cells and the motile cilia that are present in epithelial cells of the lungs and fallopian tubes, as well as ependymal cells of the brain ventricles. These types of cilia mediate movement. However, there is a third type of cilia, which are non-motile and present in most human cell types, referred to as primary cilia...Read more

Light-sheet microscopy has been used to visualize the 3-D anatomy of one of our smallest and most beautiful organs, the inner ear...Read more