In a recent publication in Nature Cell Biology, an integrated single-cell RNA sequencing and spatial transcriptomics strategy was used to clarify the origins and mechanisms behind cell heterogeneity in lung. The results were used to create a topographic atlas of early human lung development...Read more

The exploration of the human proteome has revealed many uncharacterized proteins with very interesting distributions in tissues and cells. Among them are many receptor proteins with unknown functions and predominant expression in the brain, including the orphan receptor GPR151...Read more

In this movie Professor Tomas Hökfelt (Karolinska Institutet) takes you on a journey to the areas of the brain affected by Alzheimer's disease...Read more

Cilia and flagella are fascinating organelles that can be seen as thin membrane-bound projections extending from the body of various cell types. Most well-known are the flagella of sperm cells and the motile cilia that are present in epithelial cells of the lungs and fallopian tubes, as well as ependymal cells of the brain ventricles. These types of cilia mediate movement. However, there is a third type of cilia, which are non-motile and present in most human cell types, referred to as primary cilia...Read more

In an Olink-sponsored Labroots webinar Professor Mathias Uhlen will describe a novel strategy based on plasma profiling and machine learning that explores the proteome signatures of 12 major cancer types and then uses the information to identify all the individual cancer types as a first step towards new diagnostic tools for cancer...Read more