News ArticlesA multi-omics strategy to discover and validate missing proteins in the ovaryIn a publication in Journal of Proteome Research transcriptomics and spatial proteomics were used to investigate and validate the expression of so-called missing proteins in the human ovary...Read more Image of the month - PF4 in plateletsPlatelet factor 4 (gene: PF4) is a chemokine expressed by platelets (thrombocytes) - blood cell fragments that play a key role during blood clotting. Although its normal physiological role is not completely understood, PF4 is implicated in antimicrobial activity and life-threatening thrombosis caused by adenovirus vector covid-19 vaccines...Read more Image of the month - RBP2 in the intestinesThis month we turn the spotlight to retinol binding protein 2 (gene: RBP2), which plays an important role in the uptake of vitamin A in the intestines. Now that winter has arrived, we increasingly need good night vision and a strong immune system - two physiological processes that we have vitamin A to thank for...Read more The in situ expression of missing proteins in spermatogenesisSpermatogenesis is the process where sperm are made, and it involves thousands of genes and proteins that are activated and repressed. The function of a large proportion of these genes and proteins remains unknown and testis harbors many "missing proteins" (MPs)...Read more GATA-1, KLF-1 and IKZF1 - Transcription Factors in HematopoiesisThroughout life, blood cells are continuously formed in the bone marrow, a process known as hematopoiesis. Hematopoiesis relies on several different mediators, and defects in this system may cause severe pathological conditions...Read more |