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TMEM176A
BASAL GANGLIA - Expression summary
Protein expression
Caudatei
h
m
l
n
Glial cells: Medium
Neuronal cells: Not detected
RNA expressioni
Consensus:48.0 nTPM
HPA:48.0 nTPM
GTEx:34.5 nTPM
FANTOM5:48.5 Scaled Tags Per Million
Pig:29.0 nTPM
Mouse:31.2 nTPM
Allen mouse:1.0 Expression energy

CAUDATE - Antibody stainingi
Antibody HPA008770
Glial cells Medium
Neuronal cells Not detected



BASAL GANGLIA - HPA Brain RNA-seq
Max nTPM 48.0
Sample id Sample description nTPM
Caudate nucleus
nTPM: 44.1
2289 Male, age 61, right hemisphere 46.9
1857 Female, age 85, left hemisphere 46.5
2481 Female, age 94, left hemisphere 45.9
2290 Female, age 72, unknown 45.0
1854 Male, age 80, left hemisphere 44.5
1781 Male, age 74, unknown 43.2
2288 Male, age 75, left hemisphere 40.6
2846 Female, age 79, unknown 40.0
Claustrum
nTPM: 38.2
2196 Female, age 79, unknown 40.5
2198 Male, age 80, both hemispheres 40.2
2392 Female, age 94, both hemispheres 38.8
2491 Male, age 75, both hemispheres 38.8
1956 Male, age 74, unknown 37.7
2284 Female, age 91, both hemispheres 37.7
2292 Female, age 85, both hemispheres 37.4
2645 Female, age 72, unknown 37.1
2568 Male, age 61, both hemispheres 35.8
Globus pallidus, externus
nTPM: 48.0
1996 Male, age 80, right hemisphere 54.6
2646 Male, age 61, right hemisphere 50.5
2772 Female, age 79, unknown 49.0
2395 Male, age 75, both hemispheres 45.0
2567 Female, age 72, unknown 40.9
Globus pallidus, internus
nTPM: 45.9
2483 Female, age 94, right hemisphere 51.1
2037 Male, age 80, right hemisphere 50.1
1818 Male, age 74, unknown 48.7
2778 Female, age 91, both hemispheres 44.2
2287 Male, age 75, right hemisphere 42.8
2566 Female, age 72, unknown 42.8
2111 Female, age 85, right hemisphere 41.6
Nucleus accumbens
nTPM: 43.1
1806 Female, age 85, left hemisphere 47.6
2732 Male, age 80, right hemisphere 45.7
2698 Female, age 72, unknown 43.1
2286 Male, age 75, left hemisphere 42.9
1856 Female, age 91, right hemisphere 42.6
2391 Female, age 94, left hemisphere 41.9
1783 Male, age 74, unknown 41.6
2824 Male, age 61, right hemisphere 39.2
Nucleus basalis of Meynert
nTPM: 44.4
2569 Male, age 61, both hemispheres 52.1
2393 Male, age 80, right hemisphere 43.1
2484 Female, age 94, left hemisphere 42.5
2821 Male, age 75, both hemispheres 39.8
Nucleus of the diagonal band
nTPM: 40.6
1812 Female, age 91, both hemispheres 44.2
2775 Male, age 80, right hemisphere 41.3
2195 Female, age 85, both hemispheres 39.9
1979 Male, age 74, unknown 39.8
2029 Male, age 61, right hemisphere 37.9
Olfactory tubercle
nTPM: 40.6
1846 Male, age 80, right hemisphere 42.4
2856 Male, age 75, right hemisphere 40.7
2487 Female, age 94, left hemisphere 39.7
1998 Female, age 91, both hemispheres 39.4
Putamen
nTPM: 41.1
2482 Female, age 94, left hemisphere 46.9
1937 Female, age 91, right hemisphere 41.6
1829 Male, age 74, unknown 41.3
1838 Male, age 80, right hemisphere 40.6
2489 Female, age 72, unknown 40.1
2466 Female, age 79, unknown 38.5
2647 Male, age 75, left hemisphere 38.5
Septal nuclei
nTPM: 42.3
2394 Male, age 61, left hemisphere 45.3
2059 Female, age 85, both hemispheres 44.7
2199 Male, age 80, right hemisphere 44.6
2009 Female, age 91, both hemispheres 41.5
2629 Female, age 94, right hemisphere 40.8
2031 Female, age 72, unknown 40.2
1960 Male, age 74, unknown 39.2

BASAL GANGLIA - GTEx RNA-seqi
Max average nTPM 34.5
GTEx sample id Sample description nTPM
Brain - Caudate (basal ganglia)
Average nTPM: 31.4
Samples: 246

Max nTPM: 100.4
Min nTPM: 5.7
Std nTPM: 16.3
Median nTPM: 28.6
GTEX-1RNSC-0011-R5a-SM-EZ6N5 60-69 years, male 100.4
GTEX-139T8-0011-R5b-SM-5J1MO 60-69 years, male 97.0
GTEX-1EH9U-0011-R5a-SM-CJI2K 60-69 years, male 96.1
GTEX-OXRO-0011-R5A-SM-2I5EG 60-69 years, female 85.1
GTEX-1I19N-0011-R5b-SM-ARU6X 70-79 years, male 69.8
GTEX-183WM-0011-R5a-SM-718A4 70-79 years, female 67.7
GTEX-1J8EW-0011-R5b-SM-ARU8B 60-69 years, female 67.1
GTEX-11TTK-0011-R5a-SM-DNZZV 60-69 years, female 65.2
GTEX-1C6VR-0011-R5a-SM-9QEH1 60-69 years, male 64.8
GTEX-1H2FU-0011-R5b-SM-CL552 60-69 years, female 62.6
GTEX-1A8G6-0011-R5b-SM-7IGQG 60-69 years, male 62.4
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Brain - Nucleus accumbens (basal ganglia)
Average nTPM: 34.5
Samples: 246

Max nTPM: 152.5
Min nTPM: 8.6
Std nTPM: 20.8
Median nTPM: 28.4
GTEX-1RLM8-0011-R6a-SM-EYYXS 50-59 years, male 152.5
GTEX-14753-0011-R6b-SM-5S2UD 60-69 years, male 146.9
GTEX-1R46S-0011-R6a-SM-EZ6N6 60-69 years, female 106.0
GTEX-1H3VE-0011-R6b-SM-A9G1M 40-49 years, male 103.5
GTEX-ZV68-0011-R6a-SM-51MSR 50-59 years, female 94.8
GTEX-1EH9U-0011-R6a-SM-CJI2C 60-69 years, male 89.0
GTEX-1CB4H-0011-R6b-SM-CKZNK 60-69 years, female 86.2
GTEX-X261-0011-R6B-SM-4E3J8 50-59 years, male 74.3
GTEX-1LB8K-0011-R6a-SM-EXURT 50-59 years, male 74.2
GTEX-15EO6-0011-R6a-SM-7KULK 50-59 years, male 73.6
GTEX-12584-0011-R6a-SM-5NQ7C 40-49 years, male 72.9
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Brain - Putamen (basal ganglia)
Average nTPM: 32.7
Samples: 205

Max nTPM: 111.6
Min nTPM: 5.0
Std nTPM: 18.5
Median nTPM: 29.2
GTEX-1R46S-0011-R7b-SM-EXUTH 60-69 years, female 111.6
GTEX-132Q8-0011-R7b-SM-5N9F1 60-69 years, male 106.9
GTEX-1EH9U-0011-R7a-SM-9QEGU 60-69 years, male 104.5
GTEX-ZV68-0011-R7a-SM-51MT4 50-59 years, female 89.7
GTEX-1IKOH-0011-R7b-SM-CKZPH 60-69 years, female 84.6
GTEX-1LVA9-0011-R7a-SM-EYYWG 50-59 years, male 82.9
GTEX-1H3VE-0011-R7b-SM-CE6S9 40-49 years, male 72.2
GTEX-1HCU6-0011-R7b-SM-ARL77 60-69 years, female 71.9
GTEX-WWYW-0011-R7A-SM-3NB3H 50-59 years, female 71.3
GTEX-ZE7O-0011-R7a-SM-57WCU 50-59 years, female 71.3
GTEX-X261-0011-R7A-SM-4E3JJ 50-59 years, male 70.9
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BASAL GANGLIA - FANTOM5 CAGEi
Max Scaled Tags Per Million 48.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Caudate nucleus
Scaled Tags Per Million: 48.5
FF:10164-103B2 76 years, female 48.5
Globus pallidus
Scaled Tags Per Million: 41.7
FF:10161-103A8 76 years, female 54.3
FF:10175-103C4 60 years, female 29.2
Nucleus accumbens
Scaled Tags Per Million: 25.8
FF:10037-101F1 23-56 years, mixed 25.8
Putamen
Scaled Tags Per Million: 24.6
FF:10176-103C5 60 years, female 24.6

BASAL GANGLIA - Pig RNA-seqi
Average nTPM 29.0
Pig sample Sample description nTPM
Caudate
nTPM: 13.0
Samples: 4

Max nTPM: 15.5
Min nTPM: 9.8
Sample A Female 12.8
Sample B Female 13.9
Sample C Male 15.5
Sample D Male 9.8
Putamen
nTPM: 14.0
Samples: 4

Max nTPM: 16.2
Min nTPM: 11.1
Sample A Female 14.4
Sample B Female 11.1
Sample C Male 14.1
Sample D Male 16.2
Septum
nTPM: 29.0
Samples: 4

Max nTPM: 56.3
Min nTPM: 18.4
Sample A Female 19.3
Sample B Female 18.4
Sample C Male 56.3
Sample D Male 22.0
Ventral pallidum
nTPM: 17.1
Samples: 4

Max nTPM: 26.0
Min nTPM: 13.7
Sample A Female 13.7
Sample B Female 14.2
Sample C Male 26.0
Sample D Male 14.5

BASAL GANGLIA - Mouse RNA-seqi
Average nTPM 31.2
Mouse sample Sample description nTPM
Caudate putamen
nTPM: 21.8
Samples: 4

Max nTPM: 24.8
Min nTPM: 20.0
Sample A Male 24.8
Sample B Male 20.0
Sample C Female 20.0
Sample D Female 22.4
Septum
nTPM: 31.2
Samples: 4

Max nTPM: 36.4
Min nTPM: 24.0
Sample A Male 32.9
Sample B Male 24.0
Sample C Female 36.4
Sample D Female 31.3
Ventral forebrain
nTPM: 29.7
Samples: 4

Max nTPM: 41.3
Min nTPM: 20.4
Sample A Male 26.5
Sample B Male 30.4
Sample C Female 41.3
Sample D Female 20.4

BASAL GANGLIA - Allen Mouse ISHi
Max Expression energy 1.0
Allen experiment id Experiment description Expression energy
Striatum
Expression energy: 0.5
75650863 Antisense, RP_060518_02_E04, Mouse strain C57BL/6J (56 days, male) 0.5
68341358 Antisense, RP_041207_01_D09, Mouse strain C57BL/6J (56 days, male) 0.5
70813929 Antisense, RP_050725_02_F07, Mouse strain C57BL/6J (56 days, male) 0.4
Pallidum
Expression energy: 1.0
68341358 Antisense, RP_041207_01_D09, Mouse strain C57BL/6J (56 days, male) 1.6
75650863 Antisense, RP_060518_02_E04, Mouse strain C57BL/6J (56 days, male) 0.8
70813929 Antisense, RP_050725_02_F07, Mouse strain C57BL/6J (56 days, male) 0.7

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.