Explore the expression profiles of human cancers
This section contains Pathology information based on mRNA and protein expression data from 17 different forms of human cancer, together with millions of in-house generated immunohistochemically stained tissue sections images and Kaplan-Meier plots showing the correlation between mRNA expression of each human protein gene and cancer patient survival. More information about the specific content and the generation and analysis of the data in the section can be found in the Methods Summary.
Cancer statistics from relevant international and Swedish databases are summarized here, and hallmarks of cancer are described here.
Learn about:
- if the mRNA expression of a gene is prognostic for patient survival in each of the cancer types
- if a gene is enriched in a particular cancer type (specificity)
- the catalogue of genes elevated in each of the cancer types
CORRELATION ANALYSIS AND PROGNOSTIC GENESi
Each bar, number and cancer type name is clickable and they redirects to a list of genes belonging to the selected category. A gene is considered prognostic if correlation analysis of gene expression and clinical outcome resulted in Kaplan-Meier plots with high significance (p<0.001). A gene may be prognostic in more than one cancer type.
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Correlation analysis resulted in more than 10000 prognostic genes. The number of prognostic genes with regard to cancer type and association with the favorable or unfavorable clinical outcome are summarized in the interactive table below.
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