Cell line expression cluster

Remove highlighting

IDⁱ The ID of each cluster.	Main specificityⁱ The annotated specificity of the cluster. This annotation aims to reflect which type of tissues or cell types the genes of the cluster show elevated expression in. Read more	Main functionⁱ The annotated function of the cluster, based on an overrepresentation of genes associated with the annotated function. Read more	# Genesⁱ Number of genes in the cluster.	Annotation reliabilityⁱ The annotation reliability is manually set for all clusters and indicates the level of reliability of the annotated specificity and function.
1	K-562	Erythropoiesis	349	High
2	Karpas-707	Immune response	442	High
3	HMC-1	Innate immune response	506	High
4	Mesenchymal cell lines	Antiviral immune response	344	Low
5	NTERA-2	Transcription	292	Medium
6	T47d	Mammary gland	293	Medium
7	SCLC-21H	Neuronal signaling	397	High
8	SK-BR-3	Unknown function	376	Low
9	U-2 OS	Unknown function	92	Low
10	BJ & FHDF	ECM organization	568	High
11	RPE1 & U-87MG	Synaptic function	308	High
12	NES	Nervous system development	420	High
13	SH-SY5Y	Nervous system development	375	High
14	REH	Unknown function	148	Low
15	RT4	Unknown function	240	Low
16	U-266	Nucleosome	321	Medium
17	WM-115	Nervous system development	223	Medium
18	U-2197	ECM organization	305	Low
19	HEK293 & PC-3	Transcription regulation	723	Medium
20	HeLa	Mitochondria	435	Medium
21	OE19	Mitochondria	502	Medium
22	JURKAT & MOLT-4	Adaptive immune response	459	High
23	AN3-CA	Transcription regulation	154	Medium
24	NB-4	Immune response	383	High
25	RPMI-8226	Immune response	313	Medium
26	Non-specific	Cell cycle regulation	1622	Low
27	U-698-M & Daudi	Adaptive immune response	505	High
28	BEWO	Transcription regulation	389	Medium
29	U-266	Adaptive immune response	377	High
30	Epithelial cell lines	Translation	739	Medium
31	RH-30 & LHCN-M2	Muscle contraction	274	High
32	U-937	Innate immune response	284	High
33	SK-MEL-30	Melanocyte processes	391	Medium
34	Mesenchymal cell lines	ECM organization	626	High
35	RPTEC-TERT1	Kidney processes	329	High
36	HEL	Hemostasis	262	Medium
37	Hep G2	Hepatocyte cell processes	456	High
38	EFO-21	Unknown function	146	Low
39	CACO-2	Unknown function	329	Low
40	Non-specific	Basic cellular processes	557	Low
41	TIME & HUVEC/TERT2	Endothelial cell function	476	High
42	Epithelial cell lines	Epithelial cell function	593	Medium
43	THP-1	Innate immune response	255	High
44	HDLM-2	Immune response	446	High

The interactive UMAP plot displays the 44 gene clusters resulting from Louvain clustering of gene expression across all cell lines. General information about the different clusters regarding annotation and number of included genes is shown upon mouse-over, while clicking on a specific cluster in the table will highlight the selected cluster in the plot and display the general information together with a heatmap of the RNA expression across all cell lines for corresponding genes and a Gene Ontology treemap showing the enrichment of GO-terms in the cluster, where applicable.