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PHLPP1
BASAL GANGLIA - Expression summary
Protein expression
Caudatei
h
m
l
n
Glial cells: Low
Neuronal cells: Low
RNA expressioni
Consensus:74.3 nTPM
HPA:74.3 nTPM
GTEx:32.9 nTPM
FANTOM5:147.9 Scaled Tags Per Million
Pig:45.9 nTPM
Mouse:40.9 nTPM
Allen mouse:2.0 Expression energy

CAUDATE - Antibody stainingi
Antibody HPA020200
Glial cells Low
Neuronal cells Low


BASAL GANGLIA - HPA Brain RNA-seq
Max nTPM 74.3
Sample id Sample description nTPM
Caudate nucleus
nTPM: 42.2
2288 Male, age 75, left hemisphere 69.6
2481 Female, age 94, left hemisphere 48.1
2289 Male, age 61, right hemisphere 41.6
2290 Female, age 72, unknown 41.3
2846 Female, age 79, unknown 37.5
1854 Male, age 80, left hemisphere 34.2
1781 Male, age 74, unknown 33.3
1857 Female, age 85, left hemisphere 32.1
Claustrum
nTPM: 47.0
2292 Female, age 85, both hemispheres 77.4
1956 Male, age 74, unknown 59.6
2198 Male, age 80, both hemispheres 43.9
2196 Female, age 79, unknown 43.7
2568 Male, age 61, both hemispheres 43.3
2491 Male, age 75, both hemispheres 41.1
2392 Female, age 94, both hemispheres 40.3
2284 Female, age 91, both hemispheres 39.5
2645 Female, age 72, unknown 33.8
Globus pallidus, externus
nTPM: 70.6
2646 Male, age 61, right hemisphere 83.1
1996 Male, age 80, right hemisphere 79.6
2567 Female, age 72, unknown 76.2
2772 Female, age 79, unknown 61.7
2395 Male, age 75, both hemispheres 52.3
Globus pallidus, internus
nTPM: 74.3
2111 Female, age 85, right hemisphere 93.4
2778 Female, age 91, both hemispheres 81.2
2566 Female, age 72, unknown 80.8
2287 Male, age 75, right hemisphere 74.8
2037 Male, age 80, right hemisphere 72.6
1818 Male, age 74, unknown 62.3
2483 Female, age 94, right hemisphere 54.7
Nucleus accumbens
nTPM: 45.2
2286 Male, age 75, left hemisphere 60.2
2391 Female, age 94, left hemisphere 59.4
2732 Male, age 80, right hemisphere 54.0
2698 Female, age 72, unknown 47.8
1806 Female, age 85, left hemisphere 40.3
2824 Male, age 61, right hemisphere 39.0
1783 Male, age 74, unknown 38.0
1856 Female, age 91, right hemisphere 23.0
Nucleus basalis of Meynert
nTPM: 48.9
2569 Male, age 61, both hemispheres 82.3
2484 Female, age 94, left hemisphere 39.3
2821 Male, age 75, both hemispheres 39.1
2393 Male, age 80, right hemisphere 34.7
Nucleus of the diagonal band
nTPM: 24.1
1979 Male, age 74, unknown 29.7
2029 Male, age 61, right hemisphere 24.3
1812 Female, age 91, both hemispheres 23.5
2195 Female, age 85, both hemispheres 23.1
2775 Male, age 80, right hemisphere 19.9
Olfactory tubercle
nTPM: 26.2
2487 Female, age 94, left hemisphere 27.1
2856 Male, age 75, right hemisphere 26.9
1998 Female, age 91, both hemispheres 26.4
1846 Male, age 80, right hemisphere 24.6
Putamen
nTPM: 43.9
2647 Male, age 75, left hemisphere 55.7
2482 Female, age 94, left hemisphere 55.5
2489 Female, age 72, unknown 49.8
1829 Male, age 74, unknown 48.0
1937 Female, age 91, right hemisphere 37.1
2466 Female, age 79, unknown 36.3
1838 Male, age 80, right hemisphere 25.2
Septal nuclei
nTPM: 31.0
2394 Male, age 61, left hemisphere 46.0
2059 Female, age 85, both hemispheres 37.3
2199 Male, age 80, right hemisphere 32.3
2629 Female, age 94, right hemisphere 27.7
1960 Male, age 74, unknown 25.7
2031 Female, age 72, unknown 24.8
2009 Female, age 91, both hemispheres 23.5

BASAL GANGLIA - GTEx RNA-seqi
Max average nTPM 32.9
GTEx sample id Sample description nTPM
Brain - Caudate (basal ganglia)
Average nTPM: 29.6
Samples: 246

Max nTPM: 56.6
Min nTPM: 8.6
Std nTPM: 9.0
Median nTPM: 29.0
GTEX-14753-0011-R5a-SM-5S2VW 60-69 years, male 56.6
GTEX-1J8EW-0011-R5b-SM-ARU8B 60-69 years, female 55.1
GTEX-1EN7A-0011-R5a-SM-9QEH6 40-49 years, male 52.2
GTEX-13112-0011-R5b-SM-5DUV8 50-59 years, male 50.9
GTEX-17MF6-0011-R5a-SM-731BA 40-49 years, male 50.2
GTEX-13CF2-0011-R5a-SM-5LZWS 60-69 years, male 48.1
GTEX-X4XX-0011-R5A-SM-46MWN 60-69 years, male 47.1
GTEX-1C6VR-0011-R5a-SM-9QEH1 60-69 years, male 46.8
GTEX-1IL2U-0011-R5a-SM-CE6SN 60-69 years, male 46.6
GTEX-1HR98-0011-R5a-SM-A9G1V 60-69 years, male 46.3
GTEX-1IGQW-0011-R5b-SM-CJI44 60-69 years, male 46.2
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Brain - Nucleus accumbens (basal ganglia)
Average nTPM: 25.3
Samples: 246

Max nTPM: 50.6
Min nTPM: 9.5
Std nTPM: 8.6
Median nTPM: 24.3
GTEX-1EN7A-0011-R6b-SM-9QEHW 40-49 years, male 50.6
GTEX-1LB8K-0011-R6a-SM-EXURT 50-59 years, male 50.2
GTEX-1RLM8-0011-R6a-SM-EYYXS 50-59 years, male 50.1
GTEX-1H4P4-0011-R6a-SM-ARZLR 50-59 years, male 48.7
GTEX-1GN2E-0011-R6b-SM-9QEII 60-69 years, male 47.0
GTEX-131XW-0011-R6b-SM-5K7XY 50-59 years, female 46.5
GTEX-12584-0011-R6a-SM-5NQ7C 40-49 years, male 46.3
GTEX-1IL2U-0011-R6a-SM-ARZLG 60-69 years, male 45.8
GTEX-1C64N-0011-R6a-SM-7IGO9 50-59 years, male 45.3
GTEX-1IKOH-0011-R6b-SM-A9G1W 60-69 years, female 44.4
GTEX-1HFI6-0011-R6b-SM-CM2SR 40-49 years, male 44.3
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Brain - Putamen (basal ganglia)
Average nTPM: 32.9
Samples: 205

Max nTPM: 64.4
Min nTPM: 12.8
Std nTPM: 9.2
Median nTPM: 31.8
GTEX-1I1CD-0011-R7a-SM-CMKHA 60-69 years, female 64.4
GTEX-1GZ2Q-0011-R7b-SM-9OSWN 40-49 years, male 55.8
GTEX-1EN7A-0011-R7b-SM-9QEHX 40-49 years, male 54.4
GTEX-13OVL-0011-R7a-SM-5P9GW 50-59 years, male 53.0
GTEX-13QJC-0011-R7b-SM-5PNUM 60-69 years, female 52.4
GTEX-1I1GV-0011-R7a-SM-ARU6R 60-69 years, male 52.4
GTEX-1GN2E-0011-R7b-SM-9QEIJ 60-69 years, male 50.7
GTEX-1GF9V-0011-R7a-SM-CJI2R 60-69 years, male 50.6
GTEX-1I1GS-0011-R7a-SM-CM2T6 60-69 years, male 49.9
GTEX-1C64N-0011-R7a-SM-7IGOI 50-59 years, male 49.7
GTEX-1EU9M-0011-R7b-SM-9OSVU 60-69 years, male 49.0
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BASAL GANGLIA - FANTOM5 CAGEi
Max Scaled Tags Per Million 147.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Caudate nucleus
Scaled Tags Per Million: 62.1
FF:10164-103B2 76 years, female 62.1
Globus pallidus
Scaled Tags Per Million: 147.9
FF:10161-103A8 76 years, female 176.7
FF:10175-103C4 60 years, female 119.1
Nucleus accumbens
Scaled Tags Per Million: 75.4
FF:10037-101F1 23-56 years, mixed 75.4
Putamen
Scaled Tags Per Million: 51.2
FF:10176-103C5 60 years, female 51.2

BASAL GANGLIA - Pig RNA-seqi
Average nTPM 45.9
Pig sample Sample description nTPM
Caudate
nTPM: 32.2
Samples: 4

Max nTPM: 34.7
Min nTPM: 29.8
Sample A Female 29.8
Sample B Female 32.6
Sample C Male 34.7
Sample D Male 31.7
Putamen
nTPM: 45.9
Samples: 4

Max nTPM: 59.9
Min nTPM: 34.0
Sample A Female 59.9
Sample B Female 34.0
Sample C Male 40.4
Sample D Male 49.1
Septum
nTPM: 34.7
Samples: 4

Max nTPM: 37.7
Min nTPM: 32.0
Sample A Female 36.3
Sample B Female 32.0
Sample C Male 32.6
Sample D Male 37.7
Ventral pallidum
nTPM: 45.1
Samples: 4

Max nTPM: 55.2
Min nTPM: 32.1
Sample A Female 32.1
Sample B Female 39.8
Sample C Male 55.2
Sample D Male 53.4

BASAL GANGLIA - Mouse RNA-seqi
Average nTPM 40.9
Mouse sample Sample description nTPM
Caudate putamen
nTPM: 40.9
Samples: 4

Max nTPM: 41.4
Min nTPM: 40.6
Sample A Male 40.6
Sample B Male 41.4
Sample C Female 40.7
Sample D Female 40.8
Septum
nTPM: 38.5
Samples: 4

Max nTPM: 42.7
Min nTPM: 35.0
Sample A Male 35.0
Sample B Male 36.9
Sample C Female 39.3
Sample D Female 42.7
Ventral forebrain
nTPM: 34.3
Samples: 4

Max nTPM: 35.8
Min nTPM: 31.8
Sample A Male 31.8
Sample B Male 35.8
Sample C Female 34.5
Sample D Female 34.9

BASAL GANGLIA - Allen Mouse ISHi
Max Expression energy 2.0
Allen experiment id Experiment description Expression energy
Striatum
Expression energy: 1.7
70546366 Antisense, RP_050623_04_B08, Mouse strain C57BL/6J (56 days, male) 1.7
Pallidum
Expression energy: 2.0
70546366 Antisense, RP_050623_04_B08, Mouse strain C57BL/6J (56 days, male) 2.0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.