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Gene name
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Reliability score tissue (IHC)
Brain region category (RNA)
Mouse brain category (RNA)
Pig brain category (RNA)
Reliability score mouse brain
Cell type category (RNA)
Single cell type expression cluster (RNA)
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Prognostic cancer
Cancer category (RNA)
Immune cell category (RNA)
Immune cell lineage category (RNA)
Immune cell expression cluster (RNA)
Secretome annotation
Subcellular location (ICC)
Subcellular location - cell line (ICC)
Subcellular Cell Cycle Peak Phase
Reliability score cells (ICC)
Cell line category (RNA)
Cell line expression cluster (RNA)
Metabolic pathway
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NeXtProt evidence
HPA evidence
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Immunocytochemistry (ICC)
With antibodies
Has protein data
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Term
Gene name
Class
Blood group antigen proteins
Cancer-related genes
Candidate cardiovascular disease genes
CD markers
Citric acid cycle related proteins
Disease related genes
Enzymes
FDA approved drug targets
G-protein coupled receptors
Human disease related genes
Immunoglobulin genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Nuclear receptors
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RAS pathway related proteins
Ribosomal proteins
RNA polymerase related proteins
T-cell receptor genes
Transcription factors
Transporters
Voltage-gated ion channels
Subclass
Class
Biological process
Molecular function
Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
MT
Unmapped
X
Y
External id
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Breast
Bronchus
Cartilage
Caudate
Cerebellum
Cerebral cortex
Cervix
Choroid plexus
Colon
Dorsal raphe
Duodenum
Endometrium
Epididymis
Esophagus
Eye
Fallopian tube
Gallbladder
Hair
Heart muscle
Hippocampus
Hypothalamus
Kidney
Lactating breast
Liver
Lung
Lymph node
Nasopharynx
Oral mucosa
Ovary
Pancreas
Parathyroid gland
Pituitary gland
Placenta
Prostate
Rectum
Retina
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Small intestine
Smooth muscle
Soft tissue
Sole of foot
Spleen
Stomach
Substantia nigra
Testis
Thymus
Thyroid gland
Tonsil
Urinary bladder
Vagina
Cell type
Expression
Patient ID
Tissue
Any
Adipose tissue
Adrenal gland
Bone marrow
Brain
Breast
Cervix
Choroid plexus
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Intestine
Kidney
Liver
Lung
Lymphoid tissue
Ovary
Pancreas
Parathyroid gland
Pituitary gland
Placenta
Prostate
Retina
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Smooth muscle
Stomach
Testis
Thyroid gland
Tongue
Urinary bladder
Vagina
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Cluster
82:Adipose tissue - ECM organization
17:Adrenal gland - Steroid metabolism
14:B-cells - Humoral immune response
75:Bone marrow - mRNA splicing & Cell cycle
65:Brain - Ion transport
70:Brain - Nervous system development
10:Brain - Neuronal signaling
73:Brain - Neuropeptide signaling
6:Brain - Smell perception
58:Brain - Synaptic function
76:Brain & Bone marrow - Chromatin organization
32:Brain & Lymphoid tissue - Unknown function
27:Brain & Skin - Unknown function
5:Breast - Unknown function
69:Cerebellum - Gene expression regulation
88:Choroid plexus - Transmembrane transport
42:Ciliated cells - Cilium & Cell projection
49:Ciliated cells - Cilium organization
30:Epididymis - Antimicrobial activity
68:Epididymis - Unknown function
84:Esophagus - Epithelial cell function
89:Fibroblasts - ECM organization
44:Heart - Cardiac muscle contraction
38:Heart - Muscle contraction
16:Immune cells - Immune response
45:Intestine - Brush border
56:Intestine - Transmembrane transport
37:Intestine - Unknown function
87:Intestine & Kidney - Transmembrane transport
41:Intestine & Liver - Lipid metabolism
7:Kidney - Transmembrane transport
81:Kidney & Liver - Metabolism
62:Liver - Hemostasis
60:Liver - Hemostasis & Lipid metabolism
85:Liver - Metabolism
86:Liver & Placenta - Transport via ER
19:Lung - Lung function
66:Lymphoid tissue - Immune response regulation
64:Macrophages - Immune response
67:Neutrophils - Humoral immune response
40:Neutrophils - Inflammatory response
57:Non-specific - Angiogenesis
53:Non-specific - Cell cycle regulation
54:Non-specific - Microtubule organization
39:Non-specific - Mitochondria
55:Non-specific - Mitochondria & Proteasome
52:Non-specific - Ribosome
72:Non-specific - Transcription
59:Non-specific - Translation
51:Non-specific - Unknown function
29:Non-specific - Vesicular transport
25:Pancreas - Digestion
48:Parathyroid gland - membrane proteins
26:Pituitary gland - Hormone signaling
28:Placenta - Pregnancy
79:Retina - Phototransduction
77:Retina - Visual perception
20:Retina & Lymphoid tissues - Unknown function
24:Salivary gland - Salivary secretion
61:Skin - Cornification
31:Skin - Epidermis development
12:Smooth muscle tissue - Mixed function
11:Squamous epithelial cells - Epithelial cell function
4:Stomach - Digestion
33:Striated muscle - Muscle contraction
80:Striated muscle - Unknown function
63:T-cells - Adaptive immune response
23:Testis - Cell cycle regulation
71:Testis - DNA repair
83:Testis - Spermatogenesis
43:Testis - Unknown function
1:Thyroid gland - Transcription
Reliability
Enhanced
Supported
Approved
Uncertain
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Hippocampal formation
Hypothalamus
Medulla oblongata
Midbrain
Pons
Spinal cord
Thalamus
White matter
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Hippocampal formation
Hypothalamus
Midbrain
Olfactory bulb
Pituitary gland
Pons and medulla
Retina
Thalamus
White matter
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Hippocampal formation
Hypothalamus
Medulla oblongata
Midbrain
Olfactory bulb
Pituitary gland
Pons
Retina
Spinal cord
Thalamus
White matter
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Reliability
Supported
Approved
Cell type
Any
Adipocytes
Alveolar cells type 1
Alveolar cells type 2
Astrocytes
B-cells
Basal keratinocytes
Basal prostatic cells
Basal respiratory cells
Basal squamous epithelial cells
Bipolar cells
Breast glandular cells
Breast myoepithelial cells
Cardiomyocytes
Cholangiocytes
Club cells
Collecting duct cells
Cone photoreceptor cells
Cytotrophoblasts
Dendritic cells
Distal enterocytes
Distal tubular cells
Ductal cells
Early spermatids
Endometrial ciliated cells
Endometrial stromal cells
Endothelial cells
Enteroendocrine cells
Erythroid cells
Excitatory neurons
Exocrine glandular cells
Extravillous trophoblasts
Fibroblasts
Gastric mucus-secreting cells
Glandular and luminal cells
Granulocytes
Granulosa cells
Hepatic stellate cells
Hepatocytes
Hofbauer cells
Horizontal cells
Inhibitory neurons
Intestinal goblet cells
Ionocytes
Kupffer cells
Langerhans cells
Late spermatids
Leydig cells
Macrophages
Melanocytes
Microglial cells
Monocytes
Muller glia cells
NK-cells
Oligodendrocyte precursor cells
Oligodendrocytes
Pancreatic endocrine cells
Paneth cells
Peritubular cells
Plasma cells
Prostatic glandular cells
Proximal enterocytes
Proximal tubular cells
Respiratory ciliated cells
Rod photoreceptor cells
Sertoli cells
Skeletal myocytes
Smooth muscle cells
Spermatocytes
Spermatogonia
Squamous epithelial cells
Suprabasal keratinocytes
Syncytiotrophoblasts
T-cells
Theca cells
Undifferentiated cells
Urothelial cells
Category
Cell type enriched
Group enriched
Cell type enhanced
Low cell type specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Cluster
14:Adipocytes & Endothelial cells - Angiogenesis
11:Alveolar cells - Smell perception
64:Astrocytes - Nervous system maintenance
57:B-cells - Immune response
56:Bipolar cells - Visual perception
54:Cardiomyocytes - Muscle contraction
43:Cardiomyocytes - Nuclear processes
49:Ciliated cells - Cilium organization
47:Cytotrophoblasts - Unknown function
29:Early spermatids - Spermatogenesis
44:Endometrium - Transcription
45:Enterocytes - Digestion
22:Epithelial cell types - Mixed function
6:Erythroid cells - Oxygen transport
38:Extravillous trophoblasts - Unknown function
50:Fibroblasts - ECM organization
35:Glandular cells - Unknown function
60:Granulocytes - Receptor signaling
40:Granulosa cells - Unknown function
15:Hepatocytes - Hemostasis
2:Hepatocytes - Metabolism
62:Horizontal cells - Visual perception
17:Intestinal endocrine cells - Hormone signaling
53:Intestinal epithelial cells - Unknown function
28:Keratinocytes - Keratinization
41:Macrophages - Immune response
4:Macrophages - Innate immune response
30:Mammary glandular cells - Lactation
3:Monocytes - Immune response regulation
19:Monocytes & Neutrophils - Innate immune response
27:Mucus-secreting cells - Mucin production
5:Muller glia cells - Visual perception
51:Myeloid cells - Hemostasis
37:Myocytes - Muscle contraction
21:Neurons & Oligodendrocytes - Neuronal signaling
8:Neurons & Oligodendrocytes - Synaptic function
63:NK-cells & T-cells - Immune response
39:Non-specific - Basic cellular processes
12:Non-specific - Cell cycle regulation
7:Non-specific - Mitochondria
59:Non-specific - Transcription
24:Non-specific - Transcription regulation
32:Non-specific - Translation
10:Non-specific - Unknown function
68:Oligodendrocytes - Mixed function
42:Oligodendrocytes - Myelin sheath organization
1:Pancreatic cells - Digestion
16:Pancreatic endocrine cells - Mixed function
46:Photoreceptor cells - Phototransduction
55:Plasma cells - Humoral immune response
65:Plasmacytoid DCs - Unknown function
67:Proximal tubular cells - Tubular reabsorption
26:Respiratory epithelial cells - Mucosal defense
48:Smooth muscle cells - ECM organization
23:Spermatids - Flagellum & Golgi organization
31:Spermatids - Spermatogenesis
34:Spermatids - Unknown function
66:Spermatocytes - Spermatogenesis
13:Spermatocytes & Spermatogonia - Spermatogenesis
20:Spermatogonia & Spermatocytes - Spermatogenesis
61:Squamous epithelial cells - Keratinization
36:Stromal cells - Cell proliferation
18:Syncytiotrophoblasts - Pregnancy hormone signaling
58:T-cells - T-cell receptor
Tissue
Adipose subcutaneous
Adipose visceral
Breast
Colon
Heart muscle
Kidney
Liver
Lung
Pancreas
Prostate
Skeletal muscle
Skin
Stomach
Testis
Thyroid
Cell type
Enrichment
Very high
High
Moderate
Cancer
Breast cancer
Cervical cancer
Colorectal cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lung cancer
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Renal cancer
Renal cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Prognosis
Favorable
Unfavorable
Cancer
Any
Breast cancer
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Category
Cancer enriched
Group enriched
Cancer enhanced
Low cancer specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Cell type
Any
Basophil
Classical monocyte
Eosinophil
GdT-cell
Intermediate monocyte
MAIT T-cell
Memory B-cell
Memory CD4 T-cell
Memory CD8 T-cell
Myeloid DC
Naive B-cell
Naive CD4 T-cell
Naive CD8 T-cell
Neutrophil
NK-cell
Non-classical monocyte
Plasmacytoid DC
T-reg
Total PBMC
Category
Immune cell enriched
Group enriched
Immune cell enhanced
Low immune cell specificity
Not detected in immune cells
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Cell lineage
Any
B-cells
Dendritic cells
Granulocytes
Monocytes
NK-cells
T-cells
Category
Lineage enriched
Group enriched
Lineage enhanced
Low lineage specificity
Not detected
Detected in all
Detected in many
Detected in single
Is highest expressed
Cluster
23:Antigen presenting cells - Antigen presentation
21:B-cells - Adaptive immune response
43:B-cells - Humoral immune response
37:B-cells - Transcription
24:B-cells - Unknown function
41:Basophils - Cellular respiration
46:Basophils - DNA binding
38:Basophils - Unknown function
18:Basophils - Vesicular transport
45:Eosinophils - Innate immune response
52:Eosinophils - Transcription
49:Eosinophils - Unknown function
36:GdT-cells - Adaptive immune response
5:Granulocytes - Unknown function
16:MAIT-cells - Unknown function
25:Monocytes - Inflammatory response
51:Monocytes - Innate immune response
14:Monocytes - Unknown function
28:Myeloid DCs - Unknown function
50:Neutrophils - Cellular senescence
33:Neutrophils - Chromatin organization
8:Neutrophils - Inflammatory response
9:Neutrophils - Innate immune response
1:Neutrophils - Mixed function
15:NK-cells - Transcription
48:NK-cells - Unknown function
12:Non-specific - Basic cellular processes
27:Non-specific - Gene expression
31:Non-specific - Inflammatory response
26:Non-specific - Mitochondria
39:Non-specific - mRNA processing
44:Non-specific - Transcription
30:Non-specific - Translation
47:Plasmacytoid DCs - Protein folding
29:Plasmacytoid DCs - Unknown function
20:T-cells - T-cell receptor
32:T-cells - Unknown function
4:T-regs - Cell cycle regulation
35:T-regs - Unknown function
Annotation
Immunoglobulin genes
Intracellular and membrane
Secreted - unknown location
Secreted in brain
Secreted in female reproductive system
Secreted in male reproductive system
Secreted in other tissues
Secreted to blood
Secreted to digestive system
Secreted to extracellular matrix
Location
Actin filaments
Aggresome
Cell Junctions
Centriolar satellite
Centrosome
Cleavage furrow
Cytokinetic bridge
Cytoplasmic bodies
Cytosol
Endoplasmic reticulum
Endosomes
Focal adhesion sites
Golgi apparatus
Intermediate filaments
Kinetochore
Lipid droplets
Lysosomes
Microtubule ends
Microtubules
Midbody
Midbody ring
Mitochondria
Mitotic chromosome
Mitotic spindle
Nuclear bodies
Nuclear membrane
Nuclear speckles
Nucleoli
Nucleoli fibrillar center
Nucleoli rim
Nucleoplasm
Peroxisomes
Plasma membrane
Rods & Rings
Vesicles
Searches
Enhanced
Supported
Approved
Uncertain
Intensity variation
Spatial variation
CCD protein mitotic structure
CCD protein interphase
Cell cycle dependent protein
Cell cycle independent protein
Cell cycle dependent transcript
Cell cycle independent transcript
Multilocalizing
Localizing 1
Localizing 2
Localizing 3
Localizing 4
Localizing 5
Localizing 6
Main location
Additional location
Location
Any
Actin filaments
Aggresome
Cell Junctions
Centriolar satellite
Centrosome
Cleavage furrow
Cytokinetic bridge
Cytoplasmic bodies
Cytosol
Endoplasmic reticulum
Endosomes
Focal adhesion sites
Golgi apparatus
Intermediate filaments
Kinetochore
Lipid droplets
Lysosomes
Microtubule ends
Microtubules
Midbody
Midbody ring
Mitochondria
Mitotic chromosome
Mitotic spindle
Nuclear bodies
Nuclear membrane
Nuclear speckles
Nucleoli
Nucleoli fibrillar center
Nucleoli rim
Nucleoplasm
Peroxisomes
Plasma membrane
Rods & Rings
Vesicles
Cell line
Any
A-431
A549
AF22
ASC TERT1
BJ
CACO-2
EFO-21
FHDF/TERT166
GAMG
HaCaT
HAP1
HBEC3-KT
HBF TERT88
HDLM-2
HEK 293
HEL
HeLa
Hep G2
HTCEpi
HTEC/SVTERT24-B
HTERT-HME1
HTERT-RPE1
HUVEC TERT2
JURKAT
K-562
LHCN-M2
MCF7
NB-4
OE19
PC-3
REH
RH-30
RPTEC TERT1
RT4
SH-SY5Y
SiHa
SK-MEL-30
SuSa
THP-1
U-2 OS
U-251 MG
Type
Protein
Rna
Phase
G1
S
G2
Reliability
Enhanced
Supported
Approved
Uncertain
Cell line
Any
A-431
A549
AF22
AN3-CA
ASC diff
ASC TERT1
BEWO
BJ
BJ hTERT+
BJ hTERT+ SV40 Large T+
BJ hTERT+ SV40 Large T+ RasG12V
CACO-2
CAPAN-2
Daudi
EFO-21
FHDF/TERT166
GAMG
HaCaT
HAP1
HBEC3-KT
HBF TERT88
HDLM-2
HEK 293
HEL
HeLa
Hep G2
HHSteC
HL-60
HMC-1
HSkMC
HTCEpi
HTEC/SVTERT24-B
HTERT-HME1
HTERT-RPE1
HUVEC TERT2
JURKAT
K-562
Karpas-707
LHCN-M2
MCF7
MOLT-4
NB-4
NTERA-2
OE19
PC-3
REH
RH-30
RPMI-8226
RPTEC TERT1
RT4
SCLC-21H
SH-SY5Y
SiHa
SK-BR-3
SK-MEL-30
SuSa
T-47d
THP-1
TIME
U-138 MG
U-2 OS
U-2197
U-251 MG
U-266/70
U-266/84
U-698
U-87 MG
U-937
WM-115
Category
Cell line enriched
Group enriched
Cell line enhanced
Low cell line specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Cluster
23:AN3-CA - Transcription regulation
28:BEWO - Transcription regulation
10:BJ & FHDF - ECM organization
39:CACO-2 - Unknown function
38:EFO-21 - Unknown function
42:Epithelial cell lines - Epithelial cell function
30:Epithelial cell lines - Translation
44:HDLM-2 - Immune response
19:HEK293 & PC-3 - Transcription regulation
36:HEL - Hemostasis
20:HeLa - Mitochondria
37:Hep G2 - Hepatocyte cell processes
3:HMC-1 - Innate immune response
22:JURKAT & MOLT-4 - Adaptive immune response
1:K-562 - Erythropoiesis
2:Karpas-707 - Immune response
4:Mesenchymal cell lines - Antiviral immune response
34:Mesenchymal cell lines - ECM organization
24:NB-4 - Immune response
12:NES - Nervous system development
40:Non-specific - Basic cellular processes
26:Non-specific - Cell cycle regulation
5:NTERA-2 - Transcription
21:OE19 - Mitochondria
14:REH - Unknown function
31:RH-30 & LHCN-M2 - Muscle contraction
11:RPE1 & U-87MG - Synaptic function
25:RPMI-8226 - Immune response
35:RPTEC-TERT1 - Kidney processes
15:RT4 - Unknown function
7:SCLC-21H - Neuronal signaling
13:SH-SY5Y - Nervous system development
8:SK-BR-3 - Unknown function
33:SK-MEL-30 - Melanocyte processes
6:T47d - Mammary gland
43:THP-1 - Innate immune response
41:TIME & HUVEC/TERT2 - Endothelial cell function
9:U-2 OS - Unknown function
18:U-2197 - ECM organization
29:U-266 - Adaptive immune response
16:U-266 - Nucleosome
27:U-698-M & Daudi - Adaptive immune response
32:U-937 - Innate immune response
17:WM-115 - Nervous system development
Pathway
Acyl-CoA hydrolysis
Acylglycerides metabolism
Alanine; aspartate and glutamate metabolism
Amino sugar and nucleotide sugar metabolism
Aminoacyl-tRNA biosynthesis
Androgen metabolism
Arachidonic acid metabolism
Arginine and proline metabolism
Ascorbate and aldarate metabolism
Beta oxidation of branched-chain fatty acids (mitochondrial)
Beta oxidation of di-unsaturated fatty acids (n-6) (mitochondrial)
Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)
Beta oxidation of even-chain fatty acids (mitochondrial)
Beta oxidation of even-chain fatty acids (peroxisomal)
Beta oxidation of odd-chain fatty acids (mitochondrial)
Beta oxidation of phytanic acid (peroxisomal)
Beta oxidation of poly-unsaturated fatty acids (mitochondrial)
Beta oxidation of unsaturated fatty acids (n-7) (mitochondrial)
Beta oxidation of unsaturated fatty acids (n-7) (peroxisomal)
Beta oxidation of unsaturated fatty acids (n-9) (mitochondrial)
Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)
Beta-alanine metabolism
Bile acid biosynthesis
Bile acid recycling
Biopterin metabolism
Biotin metabolism
Blood group biosynthesis
Butanoate metabolism
C5-branched dibasic acid metabolism
Carnitine shuttle (cytosolic)
Carnitine shuttle (endoplasmic reticular)
Carnitine shuttle (mitochondrial)
Carnitine shuttle (peroxisomal)
Cholesterol biosynthesis 1 (Bloch pathway)
Cholesterol biosynthesis 2
Cholesterol biosynthesis 3 (Kandustch-Russell pathway)
Cholesterol metabolism
Chondroitin / heparan sulfate biosynthesis
Chondroitin sulfate degradation
CoA synthesis
Cysteine and methionine metabolism
Drug metabolism
Eicosanoid metabolism
Estrogen metabolism
Ether lipid metabolism
Fatty acid activation (cytosolic)
Fatty acid activation (endoplasmic reticular)
Fatty acid biosynthesis
Fatty acid biosynthesis (even-chain)
Fatty acid biosynthesis (odd-chain)
Fatty acid biosynthesis (unsaturated)
Fatty acid desaturation (even-chain)
Fatty acid desaturation (odd-chain)
Fatty acid elongation (even-chain)
Fatty acid elongation (odd-chain)
Fatty acid oxidation
Folate metabolism
Formation and hydrolysis of cholesterol esters
Fructose and mannose metabolism
Galactose metabolism
Glucocorticoid biosynthesis
Glutathione metabolism
Glycerolipid metabolism
Glycerophospholipid metabolism
Glycine; serine and threonine metabolism
Glycolysis / Gluconeogenesis
Glycosphingolipid biosynthesis-ganglio series
Glycosphingolipid biosynthesis-globo series
Glycosphingolipid biosynthesis-lacto and neolacto series
Glycosphingolipid metabolism
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Heme degradation
Heme synthesis
Heparan sulfate degradation
Histidine metabolism
Inositol phosphate metabolism
Isolated
Keratan sulfate biosynthesis
Keratan sulfate degradation
Leukotriene metabolism
Linoleate metabolism
Lipoic acid metabolism
Lysine metabolism
Metabolism of other amino acids
Miscellaneous
N-glycan metabolism
Nicotinate and nicotinamide metabolism
Nucleotide metabolism
O-glycan metabolism
Omega-3 fatty acid metabolism
Omega-6 fatty acid metabolism
Oxidative phosphorylation
Pantothenate and CoA biosynthesis
Pentose and glucuronate interconversions
Pentose phosphate pathway
Phenylalanine metabolism
Phenylalanine; tyrosine and tryptophan biosynthesis
Phosphatidylinositol phosphate metabolism
Pool reactions
Porphyrin metabolism
Propanoate metabolism
Prostaglandin biosynthesis
Protein assembly
Protein degradation
Protein modification
Purine metabolism
Pyrimidine metabolism
Pyruvate metabolism
Retinol metabolism
Riboflavin metabolism
ROS detoxification
Serotonin and melatonin biosynthesis
Sphingolipid metabolism
Starch and sucrose metabolism
Steroid metabolism
Sulfur metabolism
Terpenoid backbone biosynthesis
Thiamine metabolism
Transport reactions
Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolism
Tryptophan metabolism
Tyrosine metabolism
Ubiquinone synthesis
Urea cycle
Valine; leucine; and isoleucine metabolism
Vitamin A metabolism
Vitamin B12 metabolism
Vitamin B2 metabolism
Vitamin B6 metabolism
Vitamin C metabolism
Vitamin D metabolism
Vitamin E metabolism
Xenobiotics metabolism
Category
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Score
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Score
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Score
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Validation
Supported
Approved
Uncertain
Validation
Enhanced - Capture
Enhanced - Genetic
Enhanced - Independent
Enhanced - Orthogonal
Enhanced - Recombinant
Supported
Approved
Uncertain
Validation
Enhanced - Independent
Enhanced - Orthogonal
Supported
Approved
Uncertain
Validation
Enhanced - Genetic
Enhanced - Independent
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Antibodies
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Blood - conc. immunoassay
Blood - conc. mass spectrometry
Blood - detected pea
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LHX2
SUMMARY
TISSUE
BRAIN
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PATHOLOGY
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Brain proteome
MOUSE BRAIN TISSUE
Gene description
LIM homeobox 2
Mouse gene
ENSMUSG00000000247
(version 10)
Annotation summary
Broad general neuronal cytoplasmic immunoreactivity. In a subset of neurons the nucleus also positive. Choroid plexus cells are also immunoreactive.
Positive cells and structures
i
Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain.
Read more
Soma in neurons.
Choroid plexus of ependymal cells.
FRONT
BACK
Olfactory bulb
Cerebral cortex
Midbrain
Medulla
Hippocampus
Protein
Relative fluorescence intensity
i
Protein expression in
mouse brain
using immunofluorescence is reported as
mean fluorescence intensity
.
Read more
Mouse brain region
255
0
Cerebral cortex
Frontal association cortex (fra)
Motor cortex (m)
Cingulate cortex (cg)
Piriform cortex, L1 (pirl1)
Piriform cortex, L2 (pirl2)
Piriform cortex, L3 (pirl3)
Insular cortex (i)
Somatosensory cortex (s)
Retrosplenial granular cortex (rsg)
Parietal association cortex (p)
Entorhinal cortex (ent)
Visual cortex (v)
Olfactory bulb
Anterior olfactory nucleus (aon)
Granule cell layer (gro)
Internal plexiform layer (ipl)
Mitral cell layer (mi)
Glomerular layer (gl)
Rostral migratory stream (rms)
External plexiform layer (epl)
External plexiform layer of the accessory OB (epla)
N/A
Granule cell layer of the accessory OB (gra)
Glomerular layer of the accessory OB (gla)
Hippocampus
Polymorph layer of the dentate gyrus (podg)
Molecular layer of the dentate gyrus (modg)
Granular dentate gyrus (grdg)
CA1 - oriens layer (ca1or)
CA1 - pyramidal layer (ca1py)
CA1 - radiatum layer (ca1ra)
CA2 - oriens layer (ca2or)
CA2 - pyramidal layer (ca2py)
CA2 - radiatum layer (ca2ra)
CA3 - oriens layer (ca3or)
CA3 - pyramidal layer (ca3py)
CA3 - radiatum layer (ca3ra)
Stratum lucidum (slu)
Lacunosum moleculare (lmol)
Subiculum (sub)
Amygdala
Nucleus of the lateral olfactory tract (lot)
N/A
Basal medial amygdaloid nucleus (bma)
Basal lateral amygdala* (*bla)
N/A
Basal lateral amygdaloid nucleus (bla)
Cortical amygdala (aco)
Central amygdala (ce)
Medial amygdaloid nucleus (mea)
N/A
Thalamus
Medial geniculate nucleus (mg)
N/A
Parafascicular thalamic nucleus (pf)
Pregeniculate nucleus (pg)
N/A
Stria terminalis (st)
N/A
Zona incerta (zi)
Anterodorsal thalamic nucleus (ad)
Reticular thalamic nucleus (rt)
Vental anterior thalamic nucleus (va)
Medial habenular nucleus (mhb)
Laterodorsal thalamic area (ld)
Paraventricular thalamic nucleus (pv)
Central medial thalamic area (cm)
Ventral lateral thalamic area (vl)
Ventral medial thalamic area (vm)
Lateral habenulal nucleus (lhb)
Ventral posterior thalamus (vpt)
N/A
Anterior pretactal nucleus (apt)
Retromammillary nucleus (rm)
Hypothalamus
Dorsal tuberomammillary nucleus (dtm)
N/A
Mammillary nucleus (mn)
Periventricular hypothalamic nucleus (pe)
Supraoptic nucleus (so)
Tuberal nucleus (tu)
Ventral tuberomammillary nucleus (vtm)
N/A
Lateral preoptic area (lpo)
Medial preoptic area (mpo)
N/A
Suprachiasmatic nucleus (sch)
N/A
Paraventricular hypothalamic nucleus (pa)
Anterior hypothalamic area, central (ahc)
Ventral medial hypothalamic nucleus (vmh)
Ventral medial hypothalamic nucleus* (*vmh)
N/A
Arcuate nucleus (arc)
Arcuate nucleus* (*arc)
N/A
Peduncular part of lateral hypothalmus (plh)
Dorsal medial hypothalamic nucleus (dm)
Stria terminalis* (*st)
N/A
Cerebellum
Vestibulocerebellar nucleus (vecb)
N/A
Moleuclar layer of the cerebellum (cemol)
Purkinje layer of the cerebellum (cepur)
Granular layer of the cerebellum (cegr)
Pons
Barrington's nucleus (bar)
N/A
Koelliker-fuse nucleus (kf)
N/A
Motor tregiminal nucleus (5n)
N/A
Parabrachial nucleus (pbp)
Principle sensory trigeminal nucleus (pr5)
Locus coeruleus (lc)
Pontine nucleus (pn)
N/A
Vestibular nucleus (ve)
Pontine reticular nucleus, oral (pno)
Lateral lemniscus (ll)
Superior paraolivary nucleus (spo)
Circumventricular organs
Subcommissural organ (sco)
N/A
Subfornical organ (sfo)
N/A
Median eminence (me)
Medulla (ap)
N/A
Antibodies in assay
i
The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.
HPA000838