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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA050288
Most normal tissues displayed moderate nuclear positivity. Strong staining was observed in gastrointestinal tract, exocrine pancreas, renal tubules and urothelium. Bile ducts, breast and soft issues were negative
HPA051168
Normal tissues displayed weak to moderate nuclear positivity with additional cytoplasmic staining in several tissues. Strong nuclear staining was observed in exocrine pancreas and renal glomeruli while renal tubules showed strong cytoplasmic and nuclear staining. Parathyroid expressed strong cytoplasmic and membranous immunoreactivity. Cells in CNS and soft tissues were generally negative.
CAB072830
Most normal tissues displayed weak to moderate nuclear staining. Duodenum, rectum, thyroid and the neuronal cells of cerebral cortex gland showed strong staining. A subset of cells in hepatocytes, prostate, small intestine and cells in seminiferus ducts displayed moderate cytoplasmic positivity. The adrenal, bile duct cells, ovarian stromal cells along with the lymphoid and soft tissues were mostly negative.
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