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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA019511
Most of the normal cells showed weak to moderate cytoplasmic positivity with additional nuclear staining in a few cases. Strong staining was seen in exocrine pancreas, placental trophoblasts, red pulp of spleen and lymphoid cells outside reaction centra. Squamous epithelial, endometrial glands, glial cells of CNS, reaction center cells of lymphoid tissues and bile duct cells were weakly stained or negative.
HPA023088
Most normal tissues showed moderate to strong cytoplasmic positivity. Lymphoid tissues and most cells in CNS were generally weakly stained or negative.
CAB007590
Moderate to strong cytoplasmic positivity was observed in normal tissues. Strong nuclear immunoreactivity was observed in bone marrow. Most cells in lymphoid tissues were weakly stained.
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