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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA035844
Most normal tissues displayed moderate cytoplasmic immunoreactivity often combined with nuclear and membranous positivity. Esophagus, gastrointestinal glands, renal tubules, cells in seminiferus ducts and skeletal muscle were strongly stained. Glial cells and spleen were generally negative.
HPA035845
Most normal tissues displayed weak to moderate cytoplasmic positivity with additional nuclear or membranous staining in a few cases. Placental trophoblastic cells, islets of Langerhans, stomach, large intestine, renal tubules, pancreatic ducts, bile ducts and seminal vesicle were strongly stained. Prostate, lymphoid tissues and endometrial glands were negative.
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The Human Protein Atlas project is funded
