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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA007393
The majority of normal tissues showed moderate to strong cytoplasmic and nuclear positivity along with membranous staining. Cilia of respiratory epithelia and fallopian tube were distinctly stained. Most cells in CNS, lymphoid tissues, testis and heart muscle were weakly stained or negative.
CAB005076
Strong cytoplasmic and extracellular staining of many mesenchymal cells. Cytoplasmic and membranous staining was also found in most glandular and squamous epithelia. Distinct nuclear staining was also found in many cases. Microvilli stained distinctly. Membranous staining was mainly found towards lumen in gastro intestinal tract. Intra-lobular ducts in exocrine pancreas were strongly stained. CNS and lymphoid tissues were mainly negative.
CAB017560
A majority of normal tissues showed moderate cytoplasmic and/or membranous positivity. Strong staining was observed in bile ducts, exocrine pancreatic ducts, renal tubules and placental trophoblasts. Muscle cells, cells in CNS and lymphoid tissues were generally negative.
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