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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA013568
Normal tissues showed weak to moderate cytoplasmic staining. Hepatocytes and trophoblastic cells displayed strong positivity. Pneumocytes, bile duct cells, islets of Langerhans, cells in glomeruli, prostate, smooth muscle and the CNS, lymphoid along with soft tissues were negative.
HPA015535
Normal tissues generally displayed weak to moderate cytoplasmic staining. Strong membranous staining was observed in adrenal gland. Nerve fibers showed strong staining while the cells in CNS generally were negative as well as squamous epithelia and cells in female genitalia.
HPA043136
Normal tissues displayed weak to moderate cytoplasmic positivity. Strong staining was observed in occasional neuronal cells, cells in red pulp of spleen, hematopoietic cells and cardiac myocytes. The liver, placenta, glandular cells in male genital tract, glial cells and soft tissues were negative.
HPA047029
Most normal tissues showed weak to moderate cytoplasmic positivity. Purkinje cells, exocrine glandular cells in pancreas and small intestine displayed strong immunoreactivity. Neuronal cells and cells in testis displayed additional nuclear staining. Lymphoid tissues, soft tissues, lung, breast, prostate, trophoblasts and smooth muscle cells were negative.
HPA047052
A subset of non germinal center cells of tonsil displayed strong cytoplasmic staining. Colon, duodenum, pancreas, rectum and stomach were moderately positive. Remaining normal tissues were weakly stained or negative.
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