Expression of MT-ND4L in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 2488.51

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

3212.9

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	11487.5
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	10041.0
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	9570.3
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	8824.1
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	8730.2
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	8575.7
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	8520.6
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	8422.4
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	8022.2
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	7375.8
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	7104.3
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	6524.7
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	6306.2
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	6291.2
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	6202.4
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	6181.3
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	6133.8
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	6093.4
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	5964.8
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	5820.4
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	5649.7
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	5574.1
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	5527.0
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	5448.0
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	5386.8
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	5313.5
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	5281.2
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	5241.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	5084.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	5027.3
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	5019.5
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	5000.9
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	5000.2
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	4940.3
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	4783.1
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	4700.9
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	4673.6
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	4658.5
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	4595.4
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	4575.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	4398.4
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	4348.8
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	4331.5
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	4331.4
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	4290.3
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	4119.7
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	4085.6
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	3998.0
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	3916.8
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	3881.1
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	3880.3
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	3861.1
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	3856.5
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	3748.1
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	3564.0
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	3525.3
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	3503.1
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	3468.5
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	3452.2
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	3448.6
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	3366.3
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	3332.0
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	3268.5
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	3261.4
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	3257.9
TCGA-CL-4957-01A	79 years, female, dead, 425 days	3183.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	3162.7
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	3149.7
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	3106.1
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	3077.3
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	2951.7
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	2895.6
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	2894.3
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	2850.8
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	2823.6
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	2821.0
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	2812.5
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	2761.3
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	2737.6
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	2720.7
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	2520.0
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	2500.1
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	2492.5
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	2484.5
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	2474.1
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	2470.8
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	2405.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	2366.8
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	2348.4
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	2319.4
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	2291.9
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	2252.4
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	2207.2
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	2167.4
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	2114.7
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	2110.3
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	2108.3
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	2018.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	2008.4
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	1945.1
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	1914.5
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1903.1
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1870.1
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1849.8
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1836.8
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	1827.6
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1778.9
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	1778.2
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1774.8
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1707.8
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1698.3
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	1667.7
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	1657.7
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1617.1
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	1596.0
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	1594.7
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1563.4
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	1542.3
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1526.1
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	1486.3
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	1466.4
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1433.2
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	1428.7
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	1422.0
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1415.4
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	1382.2
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1366.6
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	1353.4
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	1318.3
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1283.8
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1271.6
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	1234.4
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1223.6
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	1210.1
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	1200.0
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1161.8
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	1146.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	1097.4
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	1087.9
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1067.7
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1049.6
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	1005.2
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	951.8
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	942.4
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	904.9
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	839.5
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	825.5
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	802.8
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	722.8
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	721.7
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	716.4
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	691.8
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	684.1
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	674.1
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	558.1
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	388.8
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	385.9
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	354.6
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	148.1
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