Immune cell - ZNF670 - The Human Protein Atlas

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ZNF670
Gene descriptionⁱ Full gene name according to HGNC.	Zinc finger protein 670
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular

IMMUNE CELL SECTION SUMMARY
Immune cell type expression clusterⁱ The RNA data is used to cluster genes according to their expression across immune cells. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	B-cells - Adaptive immune response (mainly)
Immune cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low immune cell specificity
Immune cell type distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Immune cell lineage specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: lineage enriched, group enriched, lineage enhanced, low lineage specificity and not detected. Lineages include B-cells, T-cells, NK-cells, monocytes, granulocytes and dendritic cells. Read more	Low lineage specificity
Immune cell lineage distributionⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	Detected in many

IMMUNE CELL TYPE EXPRESSION (RNA)ⁱ

HPA datasetⁱ

Lineage

Expression

Alphabetical

Immune cell type specificity: Low immune cell specificity

Monaco datasetⁱ

Lineage

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

ZNF670 is part of cluster 21 B-cells - Adaptive immune response with confidenceⁱ 1
241 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on immune cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
PRKCE	Protein kinase C epsilon	0.7010	37
QTRT2	Queuine tRNA-ribosyltransferase accessory subunit 2	0.6903	12
LZTFL1	Leucine zipper transcription factor like 1	0.6872	43
EHBP1	EH domain binding protein 1	0.6752	37
EPB41L5	Erythrocyte membrane protein band 4.1 like 5	0.6747	21
FCRL5	Fc receptor like 5	0.6730	21
DIP2C	Disco interacting protein 2 homolog C	0.6716	21
MARCHF3	Membrane associated ring-CH-type finger 3	0.6685	37
RADX	RPA1 related single stranded DNA binding protein, X-linked	0.6676	40
IGLV5-37	Immunoglobulin lambda variable 5-37	0.6614	21
TRMT13	TRNA methyltransferase 13 homolog	0.6583	21
RAB9B	RAB9B, member RAS oncogene family	0.6485	40
MAP2	Microtubule associated protein 2	0.6463	21
ZFP82	ZFP82 zinc finger protein	0.6458	37
C12orf42	Chromosome 12 open reading frame 42	0.6440	21