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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA029215
Most normal tissues displayed moderate cytoplasmic positivity. Strong staining was observed trophoblastic cells, cells in seminiferous duct and neuronal cells. Most lymphoid cells, breast, squamous epithelium, stroma cells in ovary and endometrial were weakly stained.
HPA044301
Most of the normal tissues displayed weak to moderate cytoplasmic staining with additional nuclear or membranous positivity in rare cases. Respiratory epithelia, keratinocytes and smooth muscle cells were strongly stained. The liver, stomach, pancreatic islets and parathyroid gland were negative.
HPA049694
Most normal tissues showed weak to moderate cytoplasmic positivity. Neuronal cells, cells in seminiferous ducts, esophagus, thyroid and follicle cells in ovary displayed strong immunoreactivity. Respiratory epithelia, fallopian tube, gall bladder, prostate and salivary gland displayed additional membranous staining. Lymph node, adipocytes and chondrocytes were generally negative.
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