Brain tissue expression of GABRA1 - Mouse brain

MOUSE BRAIN TISSUE

Gene description	Gamma-aminobutyric acid type A receptor subunit alpha1
Mouse gene	ENSMUSG00000010803 (version 10)
Annotation summary	Gamma aminobutyric acid receptor subunit alpha 1 is highly enriched in the human nervous system. In the mouse, moderate/strong-intensity diffuse/synaptic-type immunolabeling of synaptic fields is observed in multiple forebrain regions. The staining is particularly strong in the entire olfactory bulb, neocortex, amygdala nuclei, hippocampus, hypothalamus, lateral septum and some thalamic nuclei. The staining is usually weak or missing in the brainstem, with the exception of the moderate-intensity labelling of the substantia nigra, periaqueductal gray matter as well as the dorsal gray matter around the fourth venricle, including the parabrachial-locus coeruleus regions.
Positive cells and structuresⁱ Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain. Read more	Synapse in neurons.

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Human cerebellum

Olfactory bulb

Hippocampus

Cerebellum

Cerebral cortex

	Protein
	Relative fluorescence intensityⁱ Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity . Read more
Mouse brain region	255 0
Cerebral cortex
Frontal association cortex (fra)
Motor cortex (m)
Cingulate cortex (cg)
Piriform cortex, L1 (pirl1)
Piriform cortex, L2 (pirl2)
Piriform cortex, L3 (pirl3)
Insular cortex (i)
Somatosensory cortex (s)
Retrosplenial granular cortex (rsg)
Parietal association cortex (p)
Entorhinal cortex (ent)
Visual cortex (v)
Olfactory bulb
Anterior olfactory nucleus (aon)
Granule cell layer (gro)
Internal plexiform layer (ipl)
Mitral cell layer (mi)
Glomerular layer (gl)
Rostral migratory stream (rms)
External plexiform layer (epl)
External plexiform layer of the accessory OB (epla)
Granule cell layer of the accessory OB (gra)
Glomerular layer of the accessory OB (gla)
Hippocampus
Polymorph layer of the dentate gyrus (podg)
Molecular layer of the dentate gyrus (modg)
Granular dentate gyrus (grdg)
CA1 - oriens layer (ca1or)
CA1 - pyramidal layer (ca1py)
CA1 - radiatum layer (ca1ra)
CA2 - oriens layer (ca2or)
CA2 - pyramidal layer (ca2py)
CA2 - radiatum layer (ca2ra)
CA3 - oriens layer (ca3or)
CA3 - pyramidal layer (ca3py)
CA3 - radiatum layer (ca3ra)
Stratum lucidum (slu)
Lacunosum moleculare (lmol)
Subiculum (sub)
Amygdala
Nucleus of the lateral olfactory tract (lot)
Basal medial amygdaloid nucleus (bma)
Basal lateral amygdala* (*bla)	N/A
Basal lateral amygdaloid nucleus (bla)
Cortical amygdala (aco)
Central amygdala (ce)
Medial amygdaloid nucleus (mea)
Thalamus
Medial geniculate nucleus (mg)
Parafascicular thalamic nucleus (pf)
Pregeniculate nucleus (pg)
Stria terminalis (st)
Zona incerta (zi)
Anterodorsal thalamic nucleus (ad)
Reticular thalamic nucleus (rt)
Vental anterior thalamic nucleus (va)
Medial habenular nucleus (mhb)
Laterodorsal thalamic area (ld)
Paraventricular thalamic nucleus (pv)
Central medial thalamic area (cm)
Ventral lateral thalamic area (vl)	N/A
Ventral medial thalamic area (vm)
Lateral habenulal nucleus (lhb)
Ventral posterior thalamus (vpt)
Anterior pretactal nucleus (apt)
Retromammillary nucleus (rm)	N/A
Hypothalamus
Dorsal tuberomammillary nucleus (dtm)
Mammillary nucleus (mn)	N/A
Periventricular hypothalamic nucleus (pe)
Supraoptic nucleus (so)
Tuberal nucleus (tu)
Ventral tuberomammillary nucleus (vtm)
Lateral preoptic area (lpo)
Medial preoptic area (mpo)
Suprachiasmatic nucleus (sch)
Paraventricular hypothalamic nucleus (pa)
Anterior hypothalamic area, central (ahc)
Ventral medial hypothalamic nucleus (vmh)
Ventral medial hypothalamic nucleus* (*vmh)	N/A
Arcuate nucleus (arc)
Arcuate nucleus* (*arc)	N/A
Peduncular part of lateral hypothalmus (plh)
Dorsal medial hypothalamic nucleus (dm)
Stria terminalis* (*st)	N/A
Cerebellum
Vestibulocerebellar nucleus (vecb)	N/A
Moleuclar layer of the cerebellum (cemol)
Purkinje layer of the cerebellum (cepur)
Granular layer of the cerebellum (cegr)
Pons
Barrington's nucleus (bar)	N/A
Koelliker-fuse nucleus (kf)	N/A
Motor tregiminal nucleus (5n)
Parabrachial nucleus (pbp)
Principle sensory trigeminal nucleus (pr5)
Locus coeruleus (lc)
Pontine nucleus (pn)	N/A
Vestibular nucleus (ve)
Pontine reticular nucleus, oral (pno)
Lateral lemniscus (ll)
Superior paraolivary nucleus (spo)
Circumventricular organs
Subcommissural organ (sco)
Subfornical organ (sfo)
Median eminence (me)
Medulla (ap)

Antibodies in assayⁱ The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.
HPA055746