Cell line - VAMP4 - The Human Protein Atlas

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VAMP4

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	VAMP4
Gene descriptionⁱ Full gene name according to HGNC.	Vesicle associated membrane protein 4
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	U-2197 - ECM organization (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

VAMP4 is part of cluster 18 U-2197 - ECM organization with confidenceⁱ 0.89
305 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D	0.6134	18
UBXN6	UBX domain protein 6	0.6022	18
F8A3	Coagulation factor VIII associated 3	0.5919	29
LMLN	Leishmanolysin like peptidase	0.5838	16
SH3BP5L	SH3 binding domain protein 5 like	0.5818	10
IDUA	Alpha-L-iduronidase	0.5806	29
FRMPD4	FERM and PDZ domain containing 4	0.5745	29
KDSR	3-ketodihydrosphingosine reductase	0.5735	29
BPNT2	3'(2'), 5'-bisphosphate nucleotidase 2	0.5723	10
GNPDA2	Glucosamine-6-phosphate deaminase 2	0.5721	11
FAM72C	Family with sequence similarity 72 member C	0.5692	16
ACBD3	Acyl-CoA binding domain containing 3	0.5690	18
PCOLCE2	Procollagen C-endopeptidase enhancer 2	0.5668	18
TNIP3	TNFAIP3 interacting protein 3	0.5589	11
MAGEC3	MAGE family member C3	0.5575	16

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.