Cell line - STX12 - The Human Protein Atlas

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STX12

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GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	STX12
Gene descriptionⁱ Full gene name according to HGNC.	Syntaxin 12
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	BJ & FHDF - ECM organization (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

STX12 is part of cluster 10 BJ & FHDF - ECM organization with confidenceⁱ 0.98
568 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
HIC1	HIC ZBTB transcriptional repressor 1	0.6913	10
ANPEP	Alanyl aminopeptidase, membrane	0.6419	34
ATP11C	ATPase phospholipid transporting 11C	0.6148	10
DNASE1L1	Deoxyribonuclease 1 like 1	0.6111	41
GABBR2	Gamma-aminobutyric acid type B receptor subunit 2	0.6049	41
INPP1	Inositol polyphosphate-1-phosphatase	0.6043	15
CDC42EP5	CDC42 effector protein 5	0.6040	38
RAD21L1	RAD21 cohesin complex component like 1	0.5998	10
YIPF5	Yip1 domain family member 5	0.5947	10
TWSG1	Twisted gastrulation BMP signaling modulator 1	0.5935	10
GRK5	G protein-coupled receptor kinase 5	0.5842	21
BGN	Biglycan	0.5840	10
TMEM50A	Transmembrane protein 50A	0.5828	10
UBXN4	UBX domain protein 4	0.5824	10
MMP10	Matrix metallopeptidase 10	0.5816	10

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.