Cell line - HMGN3 - The Human Protein Atlas

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HMGN3

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TISSUE

BRAIN

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PATHOLOGY

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	HMGN3
Gene descriptionⁱ Full gene name according to HGNC.	High mobility group nucleosomal binding domain 3
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	NB-4 - Immune response (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

HMGN3 is part of cluster 24 NB-4 - Immune response with confidenceⁱ 1
383 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
PET100	PET100 cytochrome c oxidase chaperone	0.6194	19
SNRPG	Small nuclear ribonucleoprotein polypeptide G	0.5840	26
LTK	Leukocyte receptor tyrosine kinase	0.5789	43
UBL5	Ubiquitin like 5	0.5599	24
LIN7A	Lin-7 homolog A, crumbs cell polarity complex component	0.5516	34
PIN1	Peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.5419	24
UTP14C	UTP14C small subunit processome component	0.5417	24
HDAC8	Histone deacetylase 8	0.5411	24
RYR3	Ryanodine receptor 3	0.5372	31
LUC7L	LUC7 like	0.5368	40
ANKRD18B	Ankyrin repeat domain 18B	0.5300	24
RAC3	Rac family small GTPase 3	0.5237	19
CFAP221	Cilia and flagella associated protein 221	0.5162	35
TNF	Tumor necrosis factor	0.5132	24
N4BP2L1	NEDD4 binding protein 2 like 1	0.5126	24

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.