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SPAG16
BASAL GANGLIA - Expression summary
Protein expression
Caudatei
h
m
l
n
Glial cells: Low
Neuronal cells: Medium
RNA expressioni
Consensus:37.4 nTPM
HPA:37.4 nTPM
GTEx:40.8 nTPM
FANTOM5:90.9 Scaled Tags Per Million
Pig:15.7 nTPM
Mouse:5.1 nTPM
Allen mouse:0.2 Expression energy

CAUDATE - Antibody stainingi
Antibody HPA037542
Glial cells Low
Neuronal cells Medium



BASAL GANGLIA - HPA Brain RNA-seq
Max nTPM 37.4
Sample id Sample description nTPM
Caudate nucleus
nTPM: 34.7
2846 Female, age 79, unknown 37.6
1857 Female, age 85, left hemisphere 36.4
2481 Female, age 94, left hemisphere 35.9
1854 Male, age 80, left hemisphere 35.6
2290 Female, age 72, unknown 34.9
2288 Male, age 75, left hemisphere 33.4
2289 Male, age 61, right hemisphere 32.9
1781 Male, age 74, unknown 31.2
Claustrum
nTPM: 31.9
2491 Male, age 75, both hemispheres 35.0
2196 Female, age 79, unknown 34.2
2392 Female, age 94, both hemispheres 32.9
1956 Male, age 74, unknown 32.8
2198 Male, age 80, both hemispheres 31.4
2568 Male, age 61, both hemispheres 30.7
2292 Female, age 85, both hemispheres 30.3
2645 Female, age 72, unknown 30.2
2284 Female, age 91, both hemispheres 29.6
Globus pallidus, externus
nTPM: 37.4
1996 Male, age 80, right hemisphere 39.3
2772 Female, age 79, unknown 38.1
2567 Female, age 72, unknown 36.8
2646 Male, age 61, right hemisphere 36.8
2395 Male, age 75, both hemispheres 36.1
Globus pallidus, internus
nTPM: 37.3
2483 Female, age 94, right hemisphere 40.5
2287 Male, age 75, right hemisphere 39.9
1818 Male, age 74, unknown 36.7
2778 Female, age 91, both hemispheres 36.5
2037 Male, age 80, right hemisphere 36.2
2566 Female, age 72, unknown 35.6
2111 Female, age 85, right hemisphere 35.5
Nucleus accumbens
nTPM: 35.4
2732 Male, age 80, right hemisphere 36.8
2698 Female, age 72, unknown 36.3
2824 Male, age 61, right hemisphere 36.3
2391 Female, age 94, left hemisphere 35.6
1806 Female, age 85, left hemisphere 35.3
2286 Male, age 75, left hemisphere 35.2
1856 Female, age 91, right hemisphere 34.8
1783 Male, age 74, unknown 33.0
Nucleus basalis of Meynert
nTPM: 34.9
2569 Male, age 61, both hemispheres 38.5
2393 Male, age 80, right hemisphere 35.7
2484 Female, age 94, left hemisphere 33.1
2821 Male, age 75, both hemispheres 32.3
Nucleus of the diagonal band
nTPM: 32.7
1812 Female, age 91, both hemispheres 34.6
1979 Male, age 74, unknown 34.3
2775 Male, age 80, right hemisphere 33.2
2195 Female, age 85, both hemispheres 31.0
2029 Male, age 61, right hemisphere 30.4
Olfactory tubercle
nTPM: 31.3
1846 Male, age 80, right hemisphere 33.1
2856 Male, age 75, right hemisphere 32.6
1998 Female, age 91, both hemispheres 29.8
2487 Female, age 94, left hemisphere 29.8
Putamen
nTPM: 34.4
1838 Male, age 80, right hemisphere 36.4
1829 Male, age 74, unknown 35.3
2647 Male, age 75, left hemisphere 34.7
1937 Female, age 91, right hemisphere 34.4
2466 Female, age 79, unknown 33.6
2482 Female, age 94, left hemisphere 33.5
2489 Female, age 72, unknown 32.9
Septal nuclei
nTPM: 32.7
2199 Male, age 80, right hemisphere 35.1
2031 Female, age 72, unknown 33.3
2629 Female, age 94, right hemisphere 33.3
2009 Female, age 91, both hemispheres 33.2
1960 Male, age 74, unknown 31.6
2059 Female, age 85, both hemispheres 31.0
2394 Male, age 61, left hemisphere 31.0

BASAL GANGLIA - GTEx RNA-seqi
Max average nTPM 40.8
GTEx sample id Sample description nTPM
Brain - Caudate (basal ganglia)
Average nTPM: 37.2
Samples: 246

Max nTPM: 88.7
Min nTPM: 20.4
Std nTPM: 11.2
Median nTPM: 34.8
GTEX-12WSA-0011-R5b-SM-5GU5I 60-69 years, male 88.7
GTEX-17HG3-0011-R5a-SM-7DUEW 30-39 years, female 75.9
GTEX-ZDXO-0011-R5a-SM-4WKG5 60-69 years, male 72.7
GTEX-1H3VE-0011-R5a-SM-CKZOU 40-49 years, male 70.2
GTEX-1E1VI-0011-R5b-SM-9WG5V 50-59 years, male 69.6
GTEX-1J8JJ-0011-R5a-SM-D4P2G 60-69 years, female 68.8
GTEX-1IKK5-0011-R5b-SM-CL55B 60-69 years, male 68.1
GTEX-QDT8-0011-R5A-SM-32PKN 30-39 years, female 64.1
GTEX-1A8G6-0011-R5b-SM-7IGQG 60-69 years, male 64.0
GTEX-1CAV2-0011-R5b-SM-9QEH4 40-49 years, female 61.9
GTEX-139TU-0011-R5b-SM-5L3E1 60-69 years, male 61.7
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Brain - Nucleus accumbens (basal ganglia)
Average nTPM: 40.5
Samples: 246

Max nTPM: 96.8
Min nTPM: 18.8
Std nTPM: 12.4
Median nTPM: 38.3
GTEX-14753-0011-R6b-SM-5S2UD 60-69 years, male 96.8
GTEX-147F4-0011-R6b-SM-5S2UP 50-59 years, male 92.7
GTEX-ZV68-0011-R6a-SM-51MSR 50-59 years, female 92.0
GTEX-P44H-0011-R6A-SM-2XCF3 40-49 years, male 85.0
GTEX-11DYG-0011-R6a-SM-DO936 60-69 years, male 83.2
GTEX-1HFI6-0011-R6b-SM-CM2SR 40-49 years, male 75.5
GTEX-1H3O1-0011-R6b-SM-CL54U 60-69 years, male 74.6
GTEX-YJ89-0011-R6a-SM-4V6GN 60-69 years, male 70.7
GTEX-1EKGG-0011-R6a-SM-CL538 60-69 years, male 69.1
GTEX-131XW-0011-R6b-SM-5K7XY 50-59 years, female 69.0
GTEX-1IGQW-0011-R6a-SM-CM2TC 60-69 years, male 64.4
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Brain - Putamen (basal ganglia)
Average nTPM: 40.8
Samples: 205

Max nTPM: 115.6
Min nTPM: 21.6
Std nTPM: 13.8
Median nTPM: 37.9
GTEX-ZE7O-0011-R7a-SM-57WCU 50-59 years, female 115.6
GTEX-13CF2-0011-R7b-SM-5K7UV 60-69 years, male 114.4
GTEX-1LVA9-0011-R7a-SM-EYYWG 50-59 years, male 92.4
GTEX-14E7W-0011-R7b-SM-5ZZV4 70-79 years, male 88.4
GTEX-12WSE-0011-R7a-SM-5PNWF 20-29 years, male 83.0
GTEX-ZV68-0011-R7a-SM-51MT4 50-59 years, female 79.1
GTEX-17MF6-0011-R7b-SM-7LG6J 40-49 years, male 77.2
GTEX-ZVZQ-0011-R7b-SM-57WBB 60-69 years, female 75.8
GTEX-12WSA-0011-R7b-SM-5GU5U 60-69 years, male 69.9
GTEX-1MA7X-0011-R7b-SM-EYYWS 60-69 years, male 67.7
GTEX-QMR6-0011-R7A-SM-32PKL 50-59 years, male 67.3
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BASAL GANGLIA - FANTOM5 CAGEi
Max Scaled Tags Per Million 90.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Caudate nucleus
Scaled Tags Per Million: 70.0
FF:10164-103B2 76 years, female 70.0
Globus pallidus
Scaled Tags Per Million: 64.5
FF:10175-103C4 60 years, female 78.9
FF:10161-103A8 76 years, female 50.2
Nucleus accumbens
Scaled Tags Per Million: 64.5
FF:10037-101F1 23-56 years, mixed 64.5
Putamen
Scaled Tags Per Million: 90.9
FF:10176-103C5 60 years, female 90.9

BASAL GANGLIA - Pig RNA-seqi
Average nTPM 15.7
Pig sample Sample description nTPM
Caudate
nTPM: 13.2
Samples: 4

Max nTPM: 15.6
Min nTPM: 11.9
Sample A Female 15.6
Sample B Female 12.5
Sample C Male 12.8
Sample D Male 11.9
Putamen
nTPM: 8.3
Samples: 4

Max nTPM: 10.4
Min nTPM: 7.3
Sample A Female 10.4
Sample B Female 7.3
Sample C Male 7.4
Sample D Male 8.1
Septum
nTPM: 15.7
Samples: 4

Max nTPM: 22.2
Min nTPM: 11.2
Sample A Female 11.2
Sample B Female 11.6
Sample C Male 17.8
Sample D Male 22.2
Ventral pallidum
nTPM: 9.3
Samples: 4

Max nTPM: 10.0
Min nTPM: 8.5
Sample A Female 9.3
Sample B Female 8.5
Sample C Male 9.5
Sample D Male 10.0

BASAL GANGLIA - Mouse RNA-seqi
Average nTPM 5.1
Mouse sample Sample description nTPM
Caudate putamen
nTPM: 1.6
Samples: 4

Max nTPM: 2.7
Min nTPM: 1.1
Sample A Male 2.7
Sample B Male 1.1
Sample C Female 1.3
Sample D Female 1.3
Septum
nTPM: 5.1
Samples: 4

Max nTPM: 5.7
Min nTPM: 3.9
Sample A Male 3.9
Sample B Male 5.7
Sample C Female 5.6
Sample D Female 5.2
Ventral forebrain
nTPM: 0.2
Samples: 4

Max nTPM: 0.3
Min nTPM: 0.1
Sample A Male 0.1
Sample B Male 0.3
Sample C Female 0.1
Sample D Female 0.2

BASAL GANGLIA - Allen Mouse ISHi
Max Expression energy 0.2
Allen experiment id Experiment description Expression energy
Striatum
Expression energy: 0.2
75080199 Antisense, RP_060412_06_H02, Mouse strain C57BL/6J (56 days, male) 0.2
71891856 Antisense, RP_051005_04_F12, Mouse strain C57BL/6J (56 days, male) 0.1
Pallidum
Expression energy: 0.1
75080199 Antisense, RP_060412_06_H02, Mouse strain C57BL/6J (56 days, male) 0.1
71891856 Antisense, RP_051005_04_F12, Mouse strain C57BL/6J (56 days, male) 0.0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.