Cell line - TRIM52 - The Human Protein Atlas

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TRIM52

SUMMARY

TISSUE

BRAIN

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METABOLIC

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TRIM52
Gene descriptionⁱ Full gene name according to HGNC.	Tripartite motif containing 52
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	HeLa - Mitochondria (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

TRIM52 is part of cluster 20 HeLa - Mitochondria with confidenceⁱ 1
435 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
ARL17A	ADP ribosylation factor like GTPase 17A	0.7196	20
FBXO46	F-box protein 46	0.6810	20
OTULIN	OTU deubiquitinase with linear linkage specificity	0.6785	20
ARHGAP11B	Rho GTPase activating protein 11B	0.6488	20
TEX52	Testis expressed 52	0.6482	20
OR2M3	Olfactory receptor family 2 subfamily M member 3	0.6462	20
OR5AS1	Olfactory receptor family 5 subfamily AS member 1	0.6433	20
SLC6A1	Solute carrier family 6 member 1	0.6356	20
PKD2L2	Polycystin 2 like 2, transient receptor potential cation channel	0.6350	20
AC097636.1	Novel protein	0.6326	20
SRRM5	Serine/arginine repetitive matrix 5	0.6279	20
ANKRD36	Ankyrin repeat domain 36	0.6192	20
MTCP1	Mature T cell proliferation 1	0.6152	20
ANKRD36B	Ankyrin repeat domain 36B	0.6083	20
TRIM66	Tripartite motif containing 66	0.6030	20

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.