Cell line - IGHJ5 - The Human Protein Atlas

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IGHJ5

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GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	IGHJ5
Gene descriptionⁱ Full gene name according to HGNC.	Immunoglobulin heavy joining 5
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Immunoglobulin genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Cell line expression clusterⁱ The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Read more	RH-30 & LHCN-M2 - Muscle contraction (mainly)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines. Read more	Group enriched (HL-60, REH, RH-30)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines. Read more	Detected in some
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at transcript level

CELL LINESⁱ

Organ

Expression

Alphabetical

EXPRESSION CLUSTERING & CORRELATIONⁱ

IGHJ5 is part of cluster 31 RH-30 & LHCN-M2 - Muscle contraction with confidenceⁱ 1
274 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on cell line RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data. Read more	Clusterⁱ ID of the expression cluster of the neighboring gene. Read more
SCN4A	Sodium voltage-gated channel alpha subunit 4	0.8901	31
AC007846.2	Novel protein	0.7435	31
FGF8	Fibroblast growth factor 8	0.7374	31
MARCHF9	Membrane associated ring-CH-type finger 9	0.7338	31
MYMX	Myomixer, myoblast fusion factor	0.7328	31
UGT2B4	UDP glucuronosyltransferase family 2 member B4	0.7308	31
MRLN	Myoregulin	0.7308	31
CHRND	Cholinergic receptor nicotinic delta subunit	0.7302	31
TSFM	Ts translation elongation factor, mitochondrial	0.7291	31
STAC3	SH3 and cysteine rich domain 3	0.7271	31
ADGRA1	Adhesion G protein-coupled receptor A1	0.7269	31
METTL1	Methyltransferase like 1	0.7245	31
MYOD1	Myogenic differentiation 1	0.7225	31
CYP2A6	Cytochrome P450 family 2 subfamily A member 6	0.7225	31
TNNI1	Troponin I1, slow skeletal type	0.7219	31

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.